PMID
stringlengths 10
13
| sentence
stringlengths 1
1.35k
| embedding
sequencelengths 384
384
|
|---|---|---|
PMID:26093789 | A comprehensive SAR analysis has been done on the results that can be used for designing new Piperine analogs with higher efficacy. | [
-0.04194829985499382,
-0.0911514014005661,
-0.08450883626937866,
-0.07652346044778824,
-0.013710474595427513,
0.022802652791142464,
-0.007304815575480461,
0.0971280187368393,
-0.0554099902510643,
-0.023821214213967323,
-0.12478040903806686,
0.024471553042531013,
-0.018547825515270233,
0.03739470988512039,
-0.09709383547306061,
0.016371114179491997,
-0.0544966422021389,
0.01675182394683361,
0.021256931126117706,
-0.055002931505441666,
-0.016441339626908302,
0.04552224278450012,
0.07565153390169144,
0.026224834844470024,
-0.09992595762014389,
0.1153719574213028,
-0.033617857843637466,
0.03288234397768974,
-0.03905290365219116,
-0.016556978225708008,
0.05639205127954483,
0.057153090834617615,
-0.011030985973775387,
-0.10666554421186447,
-0.06454640626907349,
-0.05763963237404823,
0.028183454647660255,
0.07739388942718506,
0.038826145231723785,
0.03973818197846413,
-0.004392113070935011,
0.07651814073324203,
0.049109071493148804,
0.0022900074254721403,
-0.011924183927476406,
-0.06916392594575882,
0.053730789572000504,
-0.11324860900640488,
0.016826266422867775,
-0.018398607149720192,
0.023648705333471298,
0.05405135825276375,
0.008984138257801533,
0.10501904040575027,
0.011014658957719803,
0.027131076902151108,
-0.1314018815755844,
0.0083117401227355,
-0.026682132855057716,
-0.03404266759753227,
-0.028724990785121918,
0.05924544483423233,
0.021529670804739,
0.01119596604257822,
0.016048545017838478,
0.07251615077257156,
-0.038841888308525085,
-0.03900796175003052,
0.08553431928157806,
-0.016453273594379425,
-0.04868887737393379,
-0.009274916723370552,
0.021180514246225357,
0.05806104838848114,
-0.04972485080361366,
0.06718629598617554,
0.038372259587049484,
0.047703031450510025,
0.06836609542369843,
0.015819208696484566,
-0.05754829943180084,
-0.05229059234261513,
-0.06274374574422836,
0.039114076644182205,
0.0023223916068673134,
0.1125771626830101,
0.04294638708233833,
-0.01589004322886467,
0.05590140074491501,
-0.030065402388572693,
0.05305511876940727,
0.02063625119626522,
-0.037162065505981445,
0.03784537687897682,
-0.02371729165315628,
-0.08670274168252945,
0.11123721301555634,
0.0759921595454216,
0.002835438586771488,
0.05084683746099472,
0.0017398367635905743,
-0.019648412242531776,
-0.15334384143352509,
0.0011561798164620996,
-0.05956580862402916,
-0.01656395010650158,
0.07247232645750046,
0.01926988549530506,
-0.0533103346824646,
-0.02964344248175621,
0.0008508911123499274,
0.05136367306113243,
-0.048478636890649796,
-0.02164437249302864,
0.036126647144556046,
-0.015844861045479774,
-0.0398729145526886,
-0.08995551615953445,
-0.05892935395240784,
-0.018008936196565628,
-0.06249735876917839,
-0.07977154105901718,
-0.08307070285081863,
0.07044826447963715,
0.03454658016562462,
0.03639141470193863,
-0.04969219118356705,
-5.949647107251926e-34,
0.03446046635508537,
0.05466284602880478,
0.056191857904195786,
-0.033853255212306976,
-0.0447399728000164,
0.004333831835538149,
-0.024892570450901985,
0.029157206416130066,
0.04844469577074051,
0.034199975430965424,
0.05749392881989479,
0.07389240711927414,
-0.05840406194329262,
0.0224795863032341,
-0.007207577582448721,
0.031680721789598465,
-0.041995394974946976,
-0.01968260295689106,
-0.023538118228316307,
-0.05554874241352081,
0.024286676198244095,
0.03747974708676338,
-0.05652031674981117,
0.06633219867944717,
0.00009563764615450054,
-0.007719296496361494,
-0.004205432720482349,
0.0328451506793499,
-0.007202087435871363,
0.006237339694052935,
0.03971592336893082,
-0.03022165410220623,
-0.056842606514692307,
-0.03568772226572037,
-0.07945168018341064,
-0.028606902807950974,
-0.057548053562641144,
0.05199141427874565,
0.04313340038061142,
0.10448118299245834,
0.08325260877609253,
0.02955077961087227,
0.0009714153711684048,
0.01730915531516075,
0.059893764555454254,
-0.053627852350473404,
-0.08420756459236145,
0.029938505962491035,
0.03877345472574234,
0.05898967757821083,
0.01113525778055191,
-0.05110708996653557,
0.019256683066487312,
0.10043124109506607,
0.06591317802667618,
-0.005369806662201881,
-0.04559778422117233,
-0.047833044081926346,
0.07718875259160995,
0.06692122668027878,
-0.08498679101467133,
-0.1005760058760643,
-0.014993042685091496,
-0.026337536051869392,
-0.010113690048456192,
0.03521699085831642,
-0.043933719396591187,
-0.03478260710835457,
0.00123220169916749,
0.05020458251237869,
-0.0106985317543149,
-0.0379209965467453,
-0.010326272808015347,
-0.016529494896531105,
0.01965469866991043,
0.005896331276744604,
0.001071437494829297,
0.0502605214715004,
0.08384880423545837,
0.005519759841263294,
0.0035542326513677835,
-0.00017099226533900946,
-0.007528127171099186,
0.0862656980752945,
-0.05766831338405609,
-0.029447507113218307,
0.03955214470624924,
-0.006784127093851566,
-0.05439421162009239,
0.06279175728559494,
0.024154625833034515,
0.04379808157682419,
-0.012996398843824863,
-0.05114341899752617,
-0.01013114396482706,
-7.5432859208258175e-34,
-0.015018905512988567,
0.043469902127981186,
-0.03653256967663765,
-0.005609778221696615,
-0.07854817807674408,
0.027592135593295097,
0.03679151460528374,
-0.03638720512390137,
0.05276844650506973,
-0.06774473190307617,
-0.0015304561238735914,
0.050254806876182556,
0.02277969941496849,
0.007576434873044491,
-0.06442640721797943,
0.0038175194058567286,
0.026266559958457947,
-0.09461832046508789,
0.0636812150478363,
0.009880387224256992,
0.08571179956197739,
0.048975829035043716,
-0.0371931791305542,
-0.05151140317320824,
-0.04969784617424011,
-0.02077459916472435,
0.005211716052144766,
0.01597047597169876,
0.0287766233086586,
-0.03687482699751854,
0.036299314349889755,
0.030959278345108032,
0.055856045335531235,
0.013779601082205772,
-0.03617040812969208,
0.06837233155965805,
0.11229001730680466,
-0.03000202216207981,
-0.026083145290613174,
-0.09890171140432358,
0.03137097880244255,
-0.021200591698288918,
-0.007030132692307234,
0.004985117819160223,
-0.0331227108836174,
0.05810290202498436,
0.027782319113612175,
-0.0012024652678519487,
0.052714958786964417,
0.013146521523594856,
0.013767599128186703,
-0.10126693546772003,
-0.05763201415538788,
-0.028959846124053,
0.000792697595898062,
-0.020440882071852684,
-0.04644181206822395,
-0.07818645983934402,
-0.043310414999723434,
0.01864164136350155,
0.05112336948513985,
-0.000625214132014662,
-0.029714928939938545,
-0.14542752504348755,
-0.062086157500743866,
-0.0019882041960954666,
0.022190432995557785,
0.026410294696688652,
0.08183511346578598,
-0.0012501210439950228,
0.0405554436147213,
-0.01495089940726757,
0.1188880205154419,
0.025667261332273483,
-0.0029767220839858055,
-0.10631290078163147,
0.006455916445702314,
-0.016311779618263245,
0.012106724083423615,
0.07108256220817566,
-0.02603248320519924,
0.05144771933555603,
-0.03992525488138199,
-0.09161141514778137,
0.04641881585121155,
0.11290643364191055,
-0.03367089852690697,
0.02882079780101776,
0.006815381348133087,
0.017019251361489296,
0.03470626845955849,
0.02937730960547924,
-0.049321673810482025,
0.020554427057504654,
0.02571464702486992,
-2.830731204994663e-8,
0.08247338980436325,
-0.0056918915361166,
-0.01942814141511917,
0.10130558162927628,
-0.07714488357305527,
0.021175501868128777,
-0.017945503816008568,
-0.004278169013559818,
-0.011263024993240833,
-0.0793364942073822,
0.11330106109380722,
0.0006539099267683923,
0.02381685934960842,
0.08299946039915085,
0.02554146945476532,
0.00020122808928135782,
-0.052492376416921616,
-0.0676853135228157,
-0.041159048676490784,
0.0021312758326530457,
-0.09015065431594849,
0.059936270117759705,
0.004007754381746054,
-0.0831822007894516,
-0.0010559014044702053,
0.009535386227071285,
0.02037770301103592,
-0.05812212452292442,
-0.021511757746338844,
0.03712049499154091,
-0.007334657944738865,
-0.025045737624168396,
0.05209660530090332,
0.0059455386362969875,
0.10252607613801956,
-0.01103578694164753,
-0.014257661066949368,
0.0738949179649353,
-0.015914013609290123,
-0.008929131552577019,
-0.001404901733621955,
-0.01991785690188408,
-0.0762939453125,
0.02184714935719967,
-0.02266307733952999,
-0.018265800550580025,
-0.014680375345051289,
-0.0012030631769448519,
-0.0018108877120539546,
-0.0469512902200222,
0.09241801500320435,
0.010924975387752056,
0.026728743687272072,
-0.08725421130657196,
-0.06187620013952255,
0.09193126112222672,
-0.03965993598103523,
-0.033671412616968155,
0.028356382623314857,
-0.06540688127279282,
-0.055413369089365005,
-0.044270675629377365,
-0.06563257426023483,
-0.0018435866804793477
] |
PMID:26093789 | Molecular docking computations also show that the studied compounds can bind to BIR domain of Survivin in the same binding site as that of Smac/DIABLO with a suitable binding energy. | [
-0.1073356568813324,
-0.11698771268129349,
-0.0700070708990097,
-0.015787767246365547,
-0.024423403665423393,
-0.11368577182292938,
-0.015614100731909275,
0.04809608682990074,
0.08290974050760269,
-0.003864908590912819,
-0.036270029842853546,
-0.02079574577510357,
0.011036367155611515,
0.06802161782979965,
0.0006418523262254894,
0.03625199571251869,
-0.05206778272986412,
0.0723038911819458,
0.042054612189531326,
0.0768313854932785,
0.03672923520207405,
-0.009881447069346905,
-0.011022908613085747,
-0.0844733938574791,
-0.01584452949464321,
0.05084193870425224,
0.01308441162109375,
0.07696708291769028,
0.031815335154533386,
-0.05151097849011421,
0.0799526646733284,
0.07494539767503738,
-0.0000453385291621089,
-0.05755462870001793,
0.010697701014578342,
0.025039788335561752,
-0.06187966465950012,
-0.02046951837837696,
-0.025692254304885864,
-0.050537109375,
-0.003645476186648011,
-0.005654060747474432,
0.03580360487103462,
-0.06327154487371445,
0.00902878399938345,
-0.13185884058475494,
-0.07454105466604233,
-0.005793663207441568,
0.006951954681426287,
0.07575840502977371,
-0.007693701423704624,
-0.052580125629901886,
-0.021350886672735214,
0.008327309042215347,
0.0015153571730479598,
0.06191185116767883,
-0.07457815110683441,
0.024680854752659798,
0.09862302988767624,
-0.03192676603794098,
0.0452476367354393,
-0.019171660766005516,
-0.005667743738740683,
-0.0043317778035998344,
-0.024206683039665222,
-0.04881236329674721,
0.09408043324947357,
0.05876576527953148,
-0.040752582252025604,
0.023262696340680122,
-0.022947711870074272,
-0.023127594962716103,
0.019517574459314346,
-0.05434184521436691,
0.0699412152171135,
0.09280414134263992,
-0.012668122537434101,
-0.040534619241952896,
-0.03272176533937454,
-0.004630176350474358,
-0.010086196474730968,
0.03104472905397415,
0.04669315740466118,
0.07798338681459427,
0.02068803831934929,
0.07382657378911972,
0.017536720260977745,
-0.05045066401362419,
-0.011969280429184437,
0.0013569160364568233,
0.05016566440463066,
-0.05718492716550827,
-0.04579193517565727,
-0.04959327355027199,
-0.016672713682055473,
0.006751442328095436,
-0.01508321613073349,
0.06243129447102547,
-0.01068978849798441,
-0.01626744493842125,
0.024806607514619827,
0.05340549722313881,
-0.03288095444440842,
-0.0709502100944519,
0.0013399707386270165,
0.002347010187804699,
0.11876603215932846,
0.03802516683936119,
-0.04022500663995743,
0.008379246108233929,
0.041878193616867065,
-0.00928539875894785,
0.028111470863223076,
-0.08668005466461182,
-0.05302159860730171,
0.05636818706989288,
0.0068453592248260975,
0.00690519018098712,
-0.017085717990994453,
-0.02217942290008068,
-0.04544690251350403,
0.032847948372364044,
0.047642793506383896,
-0.030627496540546417,
0.0067724427208304405,
0.029335634782910347,
-0.062220845371484756,
-1.0437396175233484e-33,
0.019189462065696716,
0.006939270533621311,
0.04177044704556465,
-0.0073189581744372845,
0.049641646444797516,
-0.13323870301246643,
-0.018431387841701508,
0.008632916025817394,
-0.13300658762454987,
-0.04050467535853386,
-0.07269664853811264,
-0.006221957039088011,
0.14166273176670074,
-0.023106317967176437,
0.03006504476070404,
-0.014842570759356022,
0.03929050639271736,
-0.011183157563209534,
0.006063125096261501,
-0.07597658038139343,
0.019147338345646858,
0.053548041731119156,
0.03252686932682991,
0.0031832410022616386,
0.09348364174365997,
0.02070925384759903,
-0.04619542881846428,
0.05763786658644676,
0.03000076301395893,
-0.0028713373467326164,
0.029867729172110558,
0.065892294049263,
-0.03543626144528389,
0.005900883115828037,
0.100376196205616,
0.07393674552440643,
0.006258203648030758,
0.012195596471428871,
-0.0427393801510334,
-0.003344245720654726,
0.06234298646450043,
-0.012366842478513718,
-0.02867112308740616,
0.05241828039288521,
-0.017985906451940536,
-0.04692554846405983,
0.02846628613770008,
0.04172741249203682,
-0.04137292131781578,
0.04443037137389183,
-0.02355431579053402,
-0.018571462482213974,
-0.05415685474872589,
0.07966385036706924,
-0.04499085247516632,
0.041897013783454895,
-0.026884671300649643,
-0.06759022921323776,
0.01717376336455345,
0.09450680017471313,
-0.06617928296327591,
0.020304232835769653,
-0.020699070766568184,
-0.020233487710356712,
-0.017617352306842804,
0.07419654726982117,
-0.07392772287130356,
-0.022082313895225525,
0.032032500952482224,
0.004063058644533157,
0.006591447629034519,
0.09197688847780228,
0.039049457758665085,
0.0069967410527169704,
0.13333284854888916,
0.03997376933693886,
-0.08223547041416168,
-0.044792816042900085,
0.06610161811113358,
0.002659832127392292,
0.02290153130888939,
-0.0504000298678875,
-0.013194936327636242,
0.012132336385548115,
-0.1434343308210373,
-0.09922467172145844,
-0.01539650559425354,
-0.007608148269355297,
-0.026567690074443817,
-0.008193280547857285,
0.08885030448436737,
-0.086368627846241,
-0.00924866646528244,
-0.13186867535114288,
-0.07309535145759583,
-1.566335018540167e-33,
0.005746583919972181,
-0.03287288174033165,
0.03382561355829239,
0.04600440710783005,
-0.06811948120594025,
0.016026847064495087,
0.01622992381453514,
-0.13428717851638794,
-0.060723524540662766,
-0.07758632302284241,
0.09271831810474396,
0.05080975219607353,
0.018660742789506912,
0.00030740140937268734,
-0.012164122425019741,
0.016489164903759956,
-0.006594086531549692,
-0.0289516132324934,
0.020684119313955307,
-0.018859948962926865,
0.028299489989876747,
-0.0256038885563612,
0.06149008497595787,
0.040391236543655396,
-0.07148021459579468,
0.003358719637617469,
0.12871572375297546,
-0.08368118107318878,
0.03739346191287041,
0.09370773285627365,
-0.012602611444890499,
0.0077665881253778934,
-0.04589245468378067,
-0.010594277642667294,
-0.010186463594436646,
0.004634950775653124,
-0.021038291975855827,
0.02662145346403122,
-0.005759967025369406,
-0.11084860563278198,
0.04790123552083969,
0.027884535491466522,
-0.03021899238228798,
0.052447326481342316,
0.09805146604776382,
-0.020112428814172745,
0.031587667763233185,
0.12450353801250458,
-0.005126293748617172,
-0.10690195113420486,
0.012812373228371143,
-0.06296985596418381,
0.042129404842853546,
-0.04305225610733032,
0.013439136557281017,
-0.0007362422766163945,
-0.03085765615105629,
-0.06544426828622818,
0.038820862770080566,
-0.03151289373636246,
0.0072352271527051926,
-0.07877123355865479,
0.05346403270959854,
0.052907444536685944,
0.025998903438448906,
-0.018116610124707222,
0.007350502535700798,
0.07399338483810425,
0.010796278715133667,
-0.13703764975070953,
-0.00004076972254551947,
-0.043588344007730484,
0.06822923570871353,
0.02023523673415184,
-0.005714524071663618,
-0.03294075280427933,
0.05842067301273346,
-0.09865719079971313,
0.012221268378198147,
-0.056890081614255905,
-0.014492512680590153,
-0.017928430810570717,
-0.00805707648396492,
-0.11288721114397049,
0.0033645681105554104,
0.04870697483420372,
0.04333772882819176,
-0.06574209034442902,
0.018454477190971375,
-0.06916289031505585,
-0.046411704272031784,
0.033119071274995804,
-0.001332647050730884,
0.03545263782143593,
0.007391700521111488,
-2.323464975972911e-8,
0.07355902343988419,
0.035801127552986145,
0.026784623041749,
0.02211303450167179,
-0.033896468579769135,
0.058581553399562836,
0.018908115103840828,
-0.04854002222418785,
0.018283668905496597,
0.14212842285633087,
0.014143843203783035,
0.05290495976805687,
-0.07439672201871872,
-0.02391628734767437,
0.06705041974782944,
0.05752185732126236,
-0.004906945861876011,
0.0045576635748147964,
-0.0351400263607502,
-0.04935992509126663,
-0.048052843660116196,
0.02529383823275566,
-0.01633535884320736,
-0.022218072786927223,
0.04918806999921799,
-0.09920419007539749,
-0.027381571009755135,
-0.0334005206823349,
0.01250099390745163,
-0.0531051866710186,
0.031724605709314346,
0.007631139364093542,
0.001116704079322517,
0.027630148455500603,
0.016352465376257896,
-0.07805167138576508,
-0.020543161779642105,
-0.02202700823545456,
0.029334163293242455,
0.0724029466509819,
0.033816996961832047,
-0.01644228585064411,
-0.024049442261457443,
-0.02008824422955513,
-0.09126576036214828,
0.03596837446093559,
0.045312538743019104,
0.05765170231461525,
-0.030311431735754013,
0.05252295359969139,
0.011689522303640842,
-0.013413820415735245,
0.03260006010532379,
-0.028341082856059074,
-0.02190009504556656,
-0.004539297893643379,
-0.043011050671339035,
0.0217463206499815,
0.033085595816373825,
0.009590108878910542,
-0.009569221176207066,
-0.023831598460674286,
-0.027702463790774345,
0.06192420423030853
] |
PMID:26093789 | This binding may result in the segregation of Smac/DIABLO in the cytosol and subsequently free Smac/DIABLO molecules could be available for binding with inhibitors of apoptosis to initiate caspase mediated apoptosis. | [
-0.10826022177934647,
-0.018503805622458458,
-0.07011382281780243,
0.03517384082078934,
0.0027109866496175528,
-0.022505009546875954,
0.028984107077121735,
0.01929267682135105,
0.08913344144821167,
0.058867305517196655,
-0.008363584987819195,
0.03229422867298126,
0.01091314759105444,
0.0268611628562212,
-0.018998650833964348,
0.08304356783628464,
-0.05091803893446922,
0.11495538055896759,
-0.008593051694333553,
0.006361318752169609,
0.002516817534342408,
-0.022301606833934784,
-0.04406895861029625,
-0.05884665623307228,
-0.009945308789610863,
0.060628555715084076,
-0.05564301460981369,
0.06323796510696411,
-0.04654549062252045,
-0.02705233544111252,
-0.042725034058094025,
-0.020848847925662994,
0.020248528569936752,
-0.0028662639670073986,
-0.007767123635858297,
0.018383748829364777,
-0.07264935225248337,
-0.026492467150092125,
-0.04864198714494705,
-0.1305837780237198,
0.03849668800830841,
0.0188368521630764,
-0.014763714745640755,
0.02123471349477768,
0.027797996997833252,
-0.08328955620527267,
-0.07752000540494919,
-0.01542927697300911,
0.015209301374852657,
0.06595325469970703,
-0.034627702087163925,
-0.09260720014572144,
0.03160075843334198,
-0.00912564154714346,
-0.0660906508564949,
0.011950907297432423,
-0.06213502585887909,
0.032811954617500305,
0.03588768467307091,
-0.014661255292594433,
-0.06384552270174026,
0.0030726406257599592,
-0.045181550085544586,
0.06856363266706467,
-0.008200721815228462,
-0.05275244265794754,
0.09342730045318604,
0.015734726563096046,
-0.10582517832517624,
0.048866502940654755,
-0.037513986229896545,
-0.046652644872665405,
0.05616549775004387,
0.04420527070760727,
0.0972658023238182,
0.06619188189506531,
0.027533629909157753,
-0.1297522485256195,
-0.030658135190606117,
0.06153419613838196,
0.07232657074928284,
0.05968175828456879,
0.03468191623687744,
0.12936362624168396,
0.02445165626704693,
0.10833247750997543,
-0.035079456865787506,
-0.03898514434695244,
0.005178087390959263,
0.0533854216337204,
-0.009208833798766136,
-0.012631600722670555,
-0.018871398642659187,
0.026977216824889183,
-0.000843913177959621,
0.06363262981176376,
-0.07013457268476486,
0.016207341104745865,
-0.08351361006498337,
0.026328401640057564,
-0.02214384451508522,
-0.020071182399988174,
-0.05677521973848343,
-0.08388709276914597,
0.013188116252422333,
0.005729984492063522,
0.03551577031612396,
-0.005260144360363483,
-0.0338016040623188,
0.0009308054577559233,
-0.014934420585632324,
-0.03031894937157631,
-0.010322659276425838,
-0.059646639972925186,
-0.014464329928159714,
0.11945398151874542,
0.004271059297025204,
0.019387725740671158,
0.05278560146689415,
-0.04379269853234291,
-0.016503119841217995,
-0.024559879675507545,
-0.0038847830146551132,
0.02625310607254505,
-0.03234777972102165,
0.06163732707500458,
0.003159643616527319,
1.5443001932630107e-33,
0.00008350744610652328,
-0.040014754980802536,
0.03109031356871128,
0.06141659617424011,
0.06926313787698746,
-0.09864778816699982,
-0.005076598841696978,
-0.053290046751499176,
-0.07004809379577637,
0.027835186570882797,
-0.052527353167533875,
-0.03137711063027382,
0.08213184028863907,
0.02204536646604538,
-0.007316060364246368,
-0.028077494353055954,
0.03933941200375557,
-0.013360573910176754,
0.006917827297002077,
-0.09026120603084564,
0.004098611883819103,
-0.015585772693157196,
0.06744575500488281,
-0.01420910656452179,
0.0351765938103199,
0.0439525805413723,
-0.054945848882198334,
0.08217582106590271,
0.021790415048599243,
0.02655208110809326,
-0.03135562315583229,
0.07629671692848206,
0.015988396480679512,
-0.006997358985245228,
0.02061104029417038,
0.04461633414030075,
-0.10466048121452332,
-0.0015921435551717877,
-0.003943785093724728,
0.05658399313688278,
-0.003101151203736663,
0.03791426122188568,
-0.0858798623085022,
-0.007082474417984486,
0.04558635503053665,
-0.08952948451042175,
-0.004960047081112862,
0.05971936881542206,
-0.06727380305528641,
0.07523642480373383,
0.024211548268795013,
-0.06134079769253731,
0.04309682548046112,
0.09807968139648438,
-0.04339482635259628,
0.06586531549692154,
-0.058515824377536774,
-0.058312445878982544,
0.02555880881845951,
0.01594414934515953,
-0.051223255693912506,
0.02109074778854847,
-0.030319619923830032,
0.07219358533620834,
-0.05981268733739853,
0.038316551595926285,
-0.05184331163764,
-0.0823454037308693,
-0.009033109061419964,
-0.010733905248343945,
0.04125465452671051,
-0.0002034215722233057,
-0.042002275586128235,
-0.003329329891130328,
0.07147921621799469,
-0.04794720560312271,
0.014317495748400688,
0.08190423250198364,
-0.021949874237179756,
0.041783496737480164,
0.07115287333726883,
-0.09148918837308884,
-0.027593234553933144,
0.0341714471578598,
-0.025377372279763222,
-0.010280687361955643,
0.0017497213557362556,
-0.019834240898489952,
-0.04224534332752228,
-0.07960069179534912,
0.05111239105463028,
-0.052885957062244415,
-0.057562727481126785,
-0.005055674817413092,
-0.0011705569922924042,
-4.133698618379531e-33,
0.028194312006235123,
-0.07019384950399399,
0.0946182981133461,
-0.03868046775460243,
-0.09166310727596283,
0.003570979693904519,
0.027654992416501045,
-0.08983830362558365,
0.04319349303841591,
0.031757939606904984,
0.04108933359384537,
0.045317184180021286,
0.0004971727612428367,
-0.03978928551077843,
0.02777414210140705,
-0.062416281551122665,
0.008032732643187046,
0.007282053120434284,
0.028604568913578987,
0.07915891706943512,
-0.03599361330270767,
0.04973186179995537,
0.04043694585561752,
0.06682068854570389,
0.04167231544852257,
-0.09799128025770187,
0.005914315115660429,
0.04759379103779793,
0.024554546922445297,
0.043411560356616974,
-0.02753998525440693,
0.03298504650592804,
0.01963735558092594,
-0.06606737524271011,
0.0030048545449972153,
-0.06963253766298294,
-0.003422326873987913,
-0.013505733571946621,
0.008050116710364819,
-0.09092303365468979,
0.04198131337761879,
0.02994382195174694,
0.007628427818417549,
0.05374251678586006,
0.0692058876156807,
0.10269730538129807,
0.006995847914367914,
0.07130119949579239,
0.04205261915922165,
-0.03791864588856697,
0.0009752276237122715,
0.006356754805892706,
-0.015139349736273289,
0.040033552795648575,
0.03535543382167816,
0.010376880876719952,
-0.02136453241109848,
-0.02316010370850563,
0.034061331301927567,
-0.04893046244978905,
-0.0469118170440197,
-0.007216747850179672,
0.03858202323317528,
0.0721839889883995,
0.13875402510166168,
0.07041939347982407,
0.04493948817253113,
0.04039613902568817,
-0.037673741579055786,
-0.08286771923303604,
0.02693428285419941,
0.030264900997281075,
-0.10591540485620499,
-0.04176796227693558,
-0.03917546942830086,
-0.04085472226142883,
-0.06989630311727524,
-0.009865384548902512,
0.010572483763098717,
-0.003566177561879158,
-0.00900306273251772,
0.0037998235784471035,
-0.016448717564344406,
-0.018719105049967766,
0.013744528405368328,
0.0006179270567372441,
-0.014937207102775574,
0.014236551709473133,
-0.012510312721133232,
0.037629932165145874,
-0.04406958818435669,
-0.022462869063019753,
0.06900089234113693,
0.02461017668247223,
-0.07315919548273087,
-3.086708133537286e-8,
0.10846234858036041,
0.007679959759116173,
0.008345214650034904,
-0.07110947370529175,
-0.13736119866371155,
-0.01174067985266447,
-0.0036088854540139437,
0.025016188621520996,
0.07029347866773605,
0.08661721646785736,
-0.042063914239406586,
0.1697111278772354,
0.001931655453518033,
0.03395842760801315,
-0.025157056748867035,
0.043121859431266785,
-0.04737578332424164,
0.014604632742702961,
-0.009968281723558903,
-0.006050084251910448,
-0.05217277631163597,
-0.027801934629678726,
0.017673863098025322,
0.0422150120139122,
0.06434270739555359,
-0.08153801411390305,
0.04094570502638817,
-0.03892698511481285,
-0.010707007721066475,
-0.12406903505325317,
-0.025739477947354317,
-0.050714585930109024,
0.06067913398146629,
-0.023049281910061836,
-0.08616751432418823,
0.0477740578353405,
-0.03578244149684906,
-0.0789833515882492,
0.02940666489303112,
0.032098062336444855,
-0.01853553205728531,
-0.044978946447372437,
0.04400911182165146,
-0.054746367037296295,
-0.09719198942184448,
0.005584986414760351,
0.0615006759762764,
-0.020960364490747452,
-0.018421465530991554,
-0.006862111389636993,
-0.01027387473732233,
0.0003372395585756749,
-0.05535975843667984,
-0.0744968056678772,
-0.02719757705926895,
-0.06270875781774521,
0.07637479901313782,
-0.022809842601418495,
0.11503931879997253,
-0.05421236902475357,
0.05898989737033844,
-0.02969544194638729,
0.015088407322764397,
-0.0076993354596197605
] |
PMID:17623656 | Matrix metalloproteinase-13 (MMP13) is a Zn(2+)-dependent protease that catalyzes the cleavage of type II collagen, the main structural protein in articular cartilage. | [
-0.10589026659727097,
-0.05728532373905182,
-0.04727538302540779,
0.009261631406843662,
0.03164706006646156,
-0.011643312871456146,
-0.01879439316689968,
0.08327016979455948,
-0.023715822026133537,
0.013652976602315903,
0.052415188401937485,
0.08636178076267242,
-0.05897445231676102,
0.07696651667356491,
-0.11230642348527908,
0.03154755383729935,
-0.05743192508816719,
0.040639445185661316,
-0.0011763883521780372,
0.04658202454447746,
-0.0014335628366097808,
0.0053749484941363335,
0.03949659690260887,
-0.08676712214946747,
0.008441788144409657,
0.01923186518251896,
0.06645255535840988,
0.018956609070301056,
-0.02678546868264675,
0.043949779123067856,
-0.03491771221160889,
0.014174449257552624,
0.037666868418455124,
-0.042389366775751114,
0.09880686551332474,
0.0005030908505432308,
0.00021580523753073066,
-0.029490888118743896,
-0.028488345444202423,
-0.016280144453048706,
0.07120224833488464,
0.013557392172515392,
0.056001774966716766,
-0.014111107215285301,
0.09940136969089508,
-0.03164559602737427,
0.010484118014574051,
-0.021724073216319084,
-0.030698273330926895,
0.17774684727191925,
-0.009561623446643353,
-0.04854005202651024,
0.06412731856107712,
0.08777119964361191,
-0.015261185355484486,
-0.0896683856844902,
-0.1415027230978012,
-0.00916577409952879,
0.03780006989836693,
0.029103180393576622,
0.03604152798652649,
0.0154059287160635,
-0.04597022756934166,
-0.011593678966164589,
0.08534577488899231,
-0.05426812916994095,
0.01824050396680832,
-0.010139100253582,
-0.11262042075395584,
0.028993884101510048,
-0.05690062791109085,
-0.026289351284503937,
-0.03984570875763893,
0.02358713373541832,
-0.008037157356739044,
0.06281951814889908,
0.007172728423029184,
-0.09255293756723404,
0.06508108973503113,
0.06075914949178696,
0.04672696441411972,
0.032924260944128036,
-0.01970214955508709,
0.07277171313762665,
0.022672757506370544,
-0.010587979108095169,
0.053577784448862076,
0.04425544664263725,
-0.06001977249979973,
-0.026666678488254547,
-0.035667307674884796,
-0.017703209072351456,
-0.07243496924638748,
0.005205112975090742,
-0.047165244817733765,
0.034562382847070694,
-0.036646321415901184,
0.046293631196022034,
0.0008830616134218872,
0.03982778266072273,
-0.023453248664736748,
0.033842913806438446,
0.08818067610263824,
-0.09566298872232437,
-0.05236976221203804,
-0.02470543049275875,
-0.022954583168029785,
0.08054105192422867,
0.07152450084686279,
0.06068466976284981,
0.013081389479339123,
-0.01065579429268837,
-0.04344852268695831,
-0.04446584731340408,
0.038292620331048965,
0.09374378621578217,
-0.023289034143090248,
0.0017025952693074942,
0.033752262592315674,
0.028083179146051407,
-0.026325242593884468,
-0.03556438535451889,
0.014754987321794033,
0.04192036762833595,
-0.06673257797956467,
0.008822906762361526,
-0.10258094221353531,
1.1466482704660855e-33,
0.0002771242870949209,
-0.03409438952803612,
0.0614367239177227,
0.023778053000569344,
-0.013435238040983677,
-0.037324078381061554,
-0.03210592642426491,
-0.06767920404672623,
-0.04817182570695877,
-0.041130322962999344,
-0.0020170260686427355,
-0.0023442315869033337,
0.09760446846485138,
-0.06815528869628906,
-0.02421005442738533,
-0.006556555163115263,
0.02535098046064377,
-0.04982000216841698,
0.09421893954277039,
-0.05775129422545433,
0.051399629563093185,
0.06300792098045349,
0.0013390366220846772,
-0.059946492314338684,
0.034076619893312454,
0.016301369294524193,
-0.01811446063220501,
0.016315540298819542,
0.05503968149423599,
-0.013769381679594517,
0.0262388177216053,
0.0010255792876705527,
-0.038004398345947266,
0.007707952056080103,
0.051374923437833786,
-0.059923384338617325,
-0.006409012712538242,
-0.10999415069818497,
0.0319250263273716,
-0.08311308175325394,
0.013527310453355312,
-0.08597522228956223,
0.006101503036916256,
-0.016591375693678856,
0.05978222191333771,
-0.05371154099702835,
-0.05180533975362778,
-0.013715396635234356,
-0.04033297300338745,
-0.04027340188622475,
0.10229168087244034,
0.05839799344539642,
0.008058984763920307,
-0.002530319383367896,
-0.05588114634156227,
0.011023511178791523,
-0.09012966603040695,
0.006835632491856813,
0.03494037687778473,
0.06140623241662979,
0.01827543042600155,
-0.08523295074701309,
-0.005837141070514917,
0.10235029458999634,
-0.019006779417395592,
-0.046216465532779694,
-0.03425893932580948,
0.018543487414717674,
-0.013139773160219193,
0.0871259868144989,
-0.0000811903883004561,
0.01961323246359825,
0.07396743446588516,
0.011696670204401016,
-0.025079503655433655,
0.05378757789731026,
0.05561060458421707,
0.1468292772769928,
0.011544621549546719,
0.036712896078825,
-0.0614568367600441,
0.0260202344506979,
-0.09424254298210144,
-0.023269115015864372,
-0.053694989532232285,
-0.02189563401043415,
-0.10156399756669998,
-0.06944946944713593,
0.02261452190577984,
-0.005121023394167423,
0.05333181098103523,
-0.03030402958393097,
-0.12652617692947388,
0.11076044291257858,
-0.047891587018966675,
-2.2003854674431774e-33,
0.03749619051814079,
-0.004044020548462868,
0.013866237364709377,
-0.06529746204614639,
-0.05114690586924553,
-0.08406483381986618,
0.07563825696706772,
0.006682789418846369,
0.015902196988463402,
0.02562796324491501,
0.07977806031703949,
-0.06962470710277557,
-0.016938280314207077,
-0.0856613889336586,
0.05215137451887131,
0.023334845900535583,
0.012224084697663784,
-0.0017911186441779137,
0.009703538380563259,
0.008572488091886044,
0.058633286505937576,
0.09012769907712936,
0.0149578507989645,
0.038520798087120056,
-0.05618464946746826,
0.03097887523472309,
-0.005761393345892429,
0.029859347268939018,
-0.0032282427418977022,
0.11440709233283997,
-0.008959266357123852,
-0.04061681404709816,
0.011561584658920765,
-0.056503184139728546,
-0.042641084641218185,
0.0418609119951725,
-0.004688382614403963,
-0.07044404000043869,
0.038049958646297455,
0.03348205238580704,
0.020713716745376587,
-0.037043504416942596,
-0.05567161738872528,
0.05672908201813698,
0.038091059774160385,
0.045216403901576996,
0.045616619288921356,
0.0030363851692527533,
0.04380007088184357,
-0.05815728008747101,
-0.006245406344532967,
0.008536647073924541,
0.004995020572096109,
-0.05202575773000717,
0.05238419026136398,
0.06467573344707489,
0.059395257383584976,
-0.009260972961783409,
0.007802536245435476,
0.07598168402910233,
0.009620615281164646,
0.03854913264513016,
0.0691404640674591,
-0.03785415366292,
0.002820938592776656,
0.10800941288471222,
-0.0350964218378067,
-0.0339154377579689,
-0.03175561502575874,
0.08460363000631332,
0.0066111525520682335,
0.0401148796081543,
-0.01866907626390457,
0.03041149117052555,
-0.011802507564425468,
-0.06903357058763504,
0.048454027622938156,
0.028571177273988724,
-0.015684574842453003,
-0.07987172901630402,
-0.05501660704612732,
-0.05967947840690613,
-0.01981332339346409,
-0.001850960310548544,
0.00843663327395916,
0.004341165069490671,
0.01631430722773075,
0.06862974911928177,
-0.008523652330040932,
0.04621890187263489,
0.008589296601712704,
-0.014652347192168236,
-0.027138007804751396,
0.10146387666463852,
-0.042208340018987656,
-2.732170401031908e-8,
-0.050072651356458664,
-0.04855227470397949,
0.020116247236728668,
-0.10235004872083664,
-0.01197452750056982,
0.00782159436494112,
0.005279812961816788,
0.03460697457194328,
0.015329052694141865,
0.027122624218463898,
0.051093172281980515,
0.012399802915751934,
-0.03607502952218056,
-0.10042087733745575,
0.007853182964026928,
0.026735767722129822,
0.017780199646949768,
-0.05651646479964256,
-0.029179872944951057,
-0.104404516518116,
0.022336916998028755,
-0.030443895608186722,
0.04977373033761978,
0.055710677057504654,
-0.08500558137893677,
-0.0501699298620224,
-0.0889953076839447,
0.09326928853988647,
-0.11232001334428787,
-0.016401080414652824,
-0.0007274399977177382,
0.041108388453722,
0.00225786748342216,
-0.040834177285432816,
-0.08039967715740204,
0.08886652439832687,
0.05673931539058685,
-0.1104571595788002,
-0.030820799991488457,
0.014195052906870842,
-0.014854311011731625,
0.020374508574604988,
0.011356350034475327,
-0.004825666081160307,
-0.038492217659950256,
0.029140425845980644,
0.00942444708198309,
0.029429467394948006,
0.03128986060619354,
0.018243107944726944,
-0.03886343538761139,
-0.043323226273059845,
-0.07043124735355377,
-0.045559175312519073,
-0.009121410548686981,
-0.0013878275640308857,
-0.008993745781481266,
-0.000654087052680552,
-0.009740530513226986,
0.045403558760881424,
-0.01621920056641102,
-0.06166981905698776,
0.09771747887134552,
-0.005389055702835321
] |
PMID:17623656 | Excess MMP13 activity causes cartilage degradation in osteoarthritis, making this protease an attractive therapeutic target. | [
-0.04752245172858238,
-0.09266339987516403,
0.034947630017995834,
0.016520291566848755,
0.02414114959537983,
0.007795833516865969,
-0.050730593502521515,
0.11321514844894409,
-0.007360642775893211,
0.03709177300333977,
-0.004352993331849575,
0.09392648935317993,
-0.02983507141470909,
0.013389911502599716,
-0.02755150757730007,
0.05905592441558838,
0.021558957174420357,
0.07484731078147888,
-0.013369453139603138,
0.027037279680371284,
0.015817569568753242,
-0.030041787773370743,
0.0833602249622345,
-0.013390136882662773,
-0.03034246154129505,
0.006824817508459091,
0.03521035239100456,
0.0137336989864707,
-0.010416705161333084,
0.026003191247582436,
-0.020631352439522743,
0.06930913776159286,
0.029089827090501785,
-0.058729685842990875,
0.07903491705656052,
0.02726530283689499,
-0.0569794699549675,
-0.03422774001955986,
-0.06430664658546448,
-0.06043753772974014,
0.03719876706600189,
-0.030365100130438805,
0.030607111752033234,
-0.04854516685009003,
0.04732975736260414,
-0.04795276001095772,
-0.042385201901197433,
0.0003323457494843751,
-0.01775505207479,
0.16519460082054138,
0.06579247862100601,
-0.0032392595894634724,
0.027808967977762222,
0.07725037634372711,
-0.040303491055965424,
-0.058207232505083084,
-0.13026440143585205,
0.054831091314554214,
0.01433869544416666,
0.06444556266069412,
0.0015307336580008268,
0.049288310110569,
-0.025786513462662697,
-0.016596443951129913,
0.05641074478626251,
-0.043307844549417496,
-0.016687190160155296,
-0.004630483686923981,
-0.11486849188804626,
0.06277210265398026,
-0.0646028220653534,
-0.02326316386461258,
-0.031199611723423004,
0.030068254098296165,
0.01992134377360344,
0.068412646651268,
-0.007368965074419975,
-0.06830919533967972,
0.029248997569084167,
0.06241176277399063,
0.028765210881829262,
0.06531377881765366,
-0.03712896257638931,
0.08272051066160202,
0.0576314814388752,
-0.014986427500844002,
0.04000423848628998,
0.005204708781093359,
-0.027979211881756783,
-0.017218811437487602,
-0.051490575075149536,
-0.025257518514990807,
-0.06567913293838501,
0.03373859450221062,
-0.011004968546330929,
0.004490090999752283,
-0.08051381260156631,
0.04870443046092987,
-0.0683048889040947,
0.017254192382097244,
-0.06953290104866028,
0.0630122572183609,
0.07582578808069229,
-0.12110470235347748,
-0.010049015283584595,
-0.03691317141056061,
-0.023401079699397087,
0.026298271492123604,
0.09278105199337006,
0.05258197337388992,
0.052794285118579865,
-0.04228520020842552,
-0.0038377856835722923,
0.011121142655611038,
0.0645972341299057,
0.09528625011444092,
-0.045313384383916855,
0.02966216951608658,
-0.01819705404341221,
0.006573222577571869,
-0.011271338909864426,
-0.05667534098029137,
-0.028135739266872406,
-0.015049494802951813,
-0.061372507363557816,
0.018081847578287125,
-0.006486379075795412,
1.4035600913489814e-33,
-0.0009257661295123398,
-0.09895098954439163,
0.04862433299422264,
0.0021233370061963797,
0.019698338583111763,
0.002515156753361225,
-0.033945679664611816,
-0.08073914796113968,
-0.028301384299993515,
-0.002707964275032282,
0.03539220243692398,
-0.0037574758753180504,
0.054384294897317886,
-0.03308873623609543,
-0.01996934786438942,
0.0021803630515933037,
0.017280491068959236,
0.006114003248512745,
0.07732304185628891,
-0.04332898557186127,
0.06587918847799301,
0.015527217648923397,
0.03158040717244148,
-0.03380729258060455,
-0.013957727700471878,
0.0003051286330446601,
-0.005852384492754936,
0.07549664378166199,
0.03293030709028244,
-0.01711021177470684,
-0.01983228512108326,
-0.015565781854093075,
-0.047994501888751984,
-0.052184972912073135,
-0.020312806591391563,
-0.04533844813704491,
-0.004815835040062666,
-0.09604041278362274,
-0.00995987094938755,
-0.04257709160447121,
-0.0038422108627855778,
-0.031085766851902008,
-0.017178239300847054,
-0.0399513840675354,
0.09366293996572495,
-0.050541989505290985,
0.014844265766441822,
0.002063827123492956,
-0.0418156236410141,
0.015363582409918308,
0.0755472406744957,
0.050726260989904404,
0.021532123908400536,
0.03929885849356651,
-0.04485699534416199,
0.03436138480901718,
-0.0662110447883606,
-0.015259111300110817,
0.04691082239151001,
0.0190686397254467,
0.002091492060571909,
-0.0900699719786644,
0.0003899739822372794,
0.10465209186077118,
0.03177088126540184,
-0.0483289510011673,
0.03818007931113243,
0.042572952806949615,
-0.07305727154016495,
0.09763482213020325,
0.06139417365193367,
0.005164490081369877,
0.04725215584039688,
0.056178946048021317,
-0.024479974061250687,
0.02188398502767086,
0.07788977026939392,
0.18714873492717743,
0.04374868795275688,
0.022055495530366898,
-0.03927652910351753,
-0.03851129487156868,
-0.11915770918130875,
0.04047660902142525,
-0.01282564364373684,
-0.029226599261164665,
-0.09833686798810959,
-0.05774170905351639,
0.03798247128725052,
-0.06253901869058609,
0.08195077627897263,
-0.038148898631334305,
-0.09689055383205414,
0.08571971952915192,
-0.07480381429195404,
-2.042605472888025e-33,
0.026999136433005333,
0.07605902850627899,
0.0311623252928257,
-0.06678714603185654,
-0.03238794207572937,
-0.006394593045115471,
-0.01186930201947689,
-0.021280871704220772,
0.012019619345664978,
-0.013910950161516666,
0.02093767374753952,
-0.0900191143155098,
-0.026020744815468788,
-0.08773724734783173,
0.02767978049814701,
-0.0007888228865340352,
0.026688799262046814,
0.026816174387931824,
-0.061885371804237366,
0.02933059260249138,
0.110249824821949,
0.10530710965394974,
-0.04380946606397629,
0.03995801880955696,
-0.010163006372749805,
0.042971447110176086,
0.010773099027574062,
0.03668459877371788,
-0.025626936927437782,
0.06664656102657318,
0.03447752445936203,
0.0029635177925229073,
-0.027875401079654694,
-0.1178429052233696,
-0.0032477497588843107,
0.03940746560692787,
0.04262317717075348,
-0.054145656526088715,
0.005867918021976948,
-0.00570415984839201,
0.046590570360422134,
-0.006192760542035103,
-0.04845338314771652,
-0.025445494800806046,
0.009485634975135326,
0.035017259418964386,
-0.007612733170390129,
-0.017477478832006454,
0.07808154076337814,
-0.06199400871992111,
0.01590205356478691,
0.01203133910894394,
-0.0015997893642634153,
-0.05505288019776344,
0.050112128257751465,
0.0326724536716938,
0.04016413912177086,
-0.05679735913872719,
0.011022096499800682,
0.05839769169688225,
0.01849396899342537,
0.05468904227018356,
0.05619090795516968,
-0.057018183171749115,
-0.0500044971704483,
0.1264018714427948,
-0.009697357192635536,
-0.07103776186704636,
-0.0603637658059597,
0.08267633616924286,
-0.05407606437802315,
0.017397630959749222,
-0.038543298840522766,
0.028899280354380608,
-0.01845795102417469,
-0.014468666166067123,
0.05348211154341698,
-0.02942047454416752,
-0.02475746162235737,
-0.09096876531839371,
-0.037278708070516586,
-0.10594972223043442,
-0.06938508152961731,
-0.06857389211654663,
-0.006619459483772516,
0.010576697997748852,
-0.027197645977139473,
0.07905025035142899,
0.005601666867733002,
0.11989334225654602,
0.002760868286713958,
-0.022343963384628296,
-0.054540060460567474,
0.06506840139627457,
0.01852133870124817,
-2.2066478422289038e-8,
0.015340275131165981,
-0.00992101151496172,
0.03970402479171753,
-0.03629300743341446,
-0.029140328988432884,
0.008866497315466404,
-0.00864643044769764,
0.07441262900829315,
-0.0165428277105093,
0.029145807027816772,
0.041377730667591095,
0.014435095712542534,
0.005205732770264149,
-0.05767473205924034,
0.058957651257514954,
0.017212947830557823,
0.05882231146097183,
-0.04227912425994873,
-0.05565768480300903,
-0.08378506451845169,
-0.012290985323488712,
-0.03423994407057762,
0.09083980321884155,
-0.017201093956828117,
-0.03784540295600891,
-0.05639893561601639,
-0.03672832250595093,
0.07261472940444946,
-0.07975080609321594,
-0.035505663603544235,
0.04071379080414772,
0.03920259699225426,
-0.03478168323636055,
-0.048260945826768875,
-0.057765986770391464,
0.07733787596225739,
0.06648984551429749,
-0.07119414955377579,
-0.040027864277362823,
0.10544004291296005,
-0.08958059549331665,
0.03263949975371361,
-0.030341632664203644,
-0.016056112945079803,
-0.07336726039648056,
0.03000192902982235,
0.010194319300353527,
0.011015426367521286,
-0.05968496948480606,
0.013938027434051037,
-0.04276953265070915,
-0.054563961923122406,
-0.025196054950356483,
-0.06255879998207092,
-0.055676668882369995,
0.06757999211549759,
-0.0036493625957518816,
0.02334357611835003,
-0.011095493100583553,
-0.0011653498513624072,
-0.03966213017702103,
-0.09632762521505356,
0.07090888917446136,
-0.0013189817545935512
] |
PMID:17623656 | However, clinically tested MMP inhibitors have been associated with a painful, joint-stiffening musculoskeletal side effect that may be due to their lack of selectivity. | [
-0.019732888787984848,
-0.046866752207279205,
0.09386042505502701,
0.09811750799417496,
-0.0214154701679945,
-0.040899842977523804,
-0.07594268769025803,
0.11551636457443237,
-0.016669003292918205,
0.02301117777824402,
-0.03191670402884483,
0.07563311606645584,
0.021907532587647438,
0.03393535315990448,
-0.04196059703826904,
0.05421546474099159,
0.06372544914484024,
0.0677185133099556,
0.07153305411338806,
0.12701551616191864,
-0.0966205820441246,
-0.012407532893121243,
-0.01671893149614334,
-0.00888121873140335,
-0.01450656820088625,
0.01817517727613449,
-0.0007986635901033878,
0.06219572201371193,
-0.002985196653753519,
0.018443472683429718,
-0.05733431875705719,
0.06846917420625687,
-0.02806806191802025,
-0.018297364935278893,
0.07984169572591782,
0.0021478363778442144,
-0.06736842542886734,
0.01443447358906269,
-0.12638691067695618,
-0.04343973472714424,
0.04781027510762215,
-0.10583826899528503,
0.03289246931672096,
-0.08473722636699677,
0.05842261016368866,
-0.025132305920124054,
-0.0625452771782875,
0.061216019093990326,
-0.050413962453603745,
0.13602033257484436,
-0.003348401514813304,
-0.005247554276138544,
0.041733115911483765,
0.012744517996907234,
-0.04599975049495697,
-0.08529895544052124,
-0.07206152379512787,
0.06073293089866638,
-0.0184281375259161,
0.025926612317562103,
-0.002291906625032425,
-0.03924867510795593,
0.038838546723127365,
0.020591096952557564,
0.08165901154279709,
0.04230888932943344,
0.008539178408682346,
-0.05044807121157646,
0.023239746689796448,
0.04544328153133392,
-0.03404342755675316,
-0.06777583807706833,
-0.03795015811920166,
0.007296212948858738,
0.005380593240261078,
-0.00551292859017849,
-0.0034148364793509245,
0.024755483493208885,
0.10518096387386322,
0.0096964780241251,
0.024626975879073143,
0.02356790378689766,
-0.05236489698290825,
0.005376151762902737,
0.009079230017960072,
0.03730851411819458,
0.006223106291145086,
0.042145587503910065,
0.004656666424125433,
-0.031072154641151428,
0.014896309934556484,
0.00765991909429431,
-0.07435630261898041,
0.007196024060249329,
0.02797864004969597,
0.014110378921031952,
-0.12977923452854156,
0.059426020830869675,
-0.1418633759021759,
-0.02755141817033291,
0.022805949673056602,
0.017212476581335068,
0.016874024644494057,
0.004147175699472427,
-0.019718296825885773,
-0.08380679041147232,
0.05599859356880188,
-0.13147497177124023,
-0.020822959020733833,
-0.007504730485379696,
0.007024030201137066,
0.027077708393335342,
-0.010354542173445225,
0.009915083646774292,
0.007524295710027218,
0.061199385672807693,
0.03900083154439926,
0.02333027869462967,
0.018191032111644745,
-0.019812917336821556,
-0.01140689942985773,
-0.09142519533634186,
-0.03226905316114426,
-0.0635036826133728,
-0.004924062639474869,
0.07600264996290207,
-0.0415048748254776,
-1.4322198374834788e-33,
-0.02934393100440502,
-0.07774510234594345,
0.01457824558019638,
0.0021277284249663353,
0.01716463267803192,
-0.02799786813557148,
-0.0619659423828125,
-0.05195651948451996,
-0.055533330887556076,
-0.03801058605313301,
-0.018205612897872925,
0.04572388157248497,
0.1115826815366745,
-0.008297665975987911,
0.016521336510777473,
0.020767759531736374,
-0.0060006543062627316,
0.035876158624887466,
0.0664491131901741,
-0.06367051601409912,
0.049314044415950775,
0.04039871320128441,
-0.004445177502930164,
0.0344979502260685,
-0.007936612702906132,
0.0784272775053978,
-0.027944039553403854,
0.04002373293042183,
0.025248246267437935,
-0.03199504315853119,
-0.08818772435188293,
-0.03204958140850067,
-0.0250559002161026,
-0.06856319308280945,
-0.05983166769146919,
0.021524136886000633,
-0.07105488330125809,
-0.057251326739788055,
-0.001060277340002358,
0.003196266945451498,
-0.02125522680580616,
0.036186911165714264,
0.03304199501872063,
-0.037420853972435,
0.07551993429660797,
-0.00939246267080307,
-0.06663861870765686,
-0.038736555725336075,
-0.036342866718769073,
0.010182385332882404,
0.026617638766765594,
0.07034143060445786,
0.024080200120806694,
0.014872796833515167,
-0.040304917842149734,
0.05716506019234657,
-0.04330822452902794,
-0.039296239614486694,
-0.020709102973341942,
0.05211437866091728,
-0.011538284830749035,
-0.045838527381420135,
-0.008651116862893105,
-0.016018187627196312,
0.005570489447563887,
0.00929925125092268,
-0.04236850142478943,
0.016425395384430885,
-0.07702500373125076,
0.02847936749458313,
0.023988664150238037,
-0.039959926158189774,
0.07666875422000885,
0.1071709617972374,
-0.01941206119954586,
-0.0399097204208374,
0.011637824587523937,
0.11753866076469421,
0.005836911499500275,
0.012094518169760704,
0.016753189265727997,
-0.09503243118524551,
-0.013809219934046268,
0.05453217402100563,
0.04739517346024513,
-0.02807224914431572,
-0.07248270511627197,
-0.12156512588262558,
0.034803785383701324,
-0.02135157212615013,
0.09582141041755676,
0.018679682165384293,
-0.08422518521547318,
0.08541202545166016,
-0.026325462386012077,
-1.5362813932449834e-33,
0.023889364674687386,
0.01646934449672699,
0.04197011888027191,
0.01748095266520977,
-0.031747590750455856,
0.0038867476396262646,
-0.01293041743338108,
-0.026974791660904884,
0.041522521525621414,
-0.009978367947041988,
0.10503086447715759,
-0.055562280118465424,
-0.11767008155584335,
-0.0547250360250473,
0.0877295583486557,
0.003275188384577632,
-0.019382933154702187,
0.04145905002951622,
0.013065789826214314,
0.05407296493649483,
0.11479867994785309,
0.05927054211497307,
0.07792659103870392,
0.03470119833946228,
0.03359592705965042,
0.010136622004210949,
0.027895526960492134,
-0.09870398789644241,
-0.0776628702878952,
0.06200511381030083,
-0.004426651168614626,
0.04684924706816673,
-0.07591812312602997,
-0.11130237579345703,
0.08448523283004761,
-0.004233100917190313,
-0.06153248995542526,
0.015465006232261658,
0.016983017325401306,
0.007403907366096973,
0.04774300009012222,
0.039535004645586014,
-0.04027434065937996,
0.04132784903049469,
0.03101128712296486,
-0.01716156117618084,
-0.03566182032227516,
-0.034574300050735474,
0.022131627425551414,
-0.02505424991250038,
-0.01860783062875271,
0.08720012754201889,
0.01781105063855648,
-0.02380606345832348,
0.036039818078279495,
-0.027100853621959686,
-0.021490752696990967,
-0.02238626778125763,
-0.011250913143157959,
0.08655741810798645,
-0.04882676899433136,
0.06638449430465698,
-0.015249191783368587,
-0.0633266344666481,
0.05106612294912338,
0.16755864024162292,
0.008712779730558395,
-0.05970778316259384,
-0.017533596605062485,
-0.004312206991016865,
-0.10148421674966812,
-0.07068289071321487,
-0.017412632703781128,
0.07817502319812775,
0.005262679886072874,
0.06071057915687561,
0.06055980175733566,
-0.022512542083859444,
-0.021315453574061394,
-0.06937410682439804,
0.011634614318609238,
-0.002509967191144824,
0.021594518795609474,
-0.05605970323085785,
-0.12633194029331207,
-0.01825825311243534,
-0.05618050694465637,
0.04938987269997597,
-0.010150224901735783,
0.05421748012304306,
0.05172896757721901,
0.019324909895658493,
-0.02992432191967964,
0.012656798586249352,
0.013744207099080086,
-3.103302859130963e-8,
-0.03944360837340355,
-0.04112617298960686,
0.02329591102898121,
-0.09387653321027756,
-0.0823955312371254,
-0.010856407694518566,
-0.09349256753921509,
0.027958611026406288,
0.0005023073172196746,
0.03976276144385338,
0.015786394476890564,
0.06341233849525452,
-0.00536931399255991,
-0.01641382835805416,
0.03370204567909241,
0.006083056330680847,
-0.014506631530821323,
0.023571183905005455,
-0.05834111571311951,
-0.022725820541381836,
-0.04327547922730446,
-0.02172483690083027,
0.08397211879491806,
0.002893467666581273,
0.030986109748482704,
-0.011127777397632599,
-0.04663383215665817,
0.014942706562578678,
-0.009801427833735943,
0.02690470591187477,
0.031757108867168427,
0.03839569166302681,
0.011769650503993034,
0.029701873660087585,
-0.04557467997074127,
0.03987469524145126,
0.0016994709149003029,
-0.014321910217404366,
-0.061489127576351166,
0.08997390419244766,
-0.0615503154695034,
0.06046310439705849,
0.012931696139276028,
-0.000026872216039919294,
-0.032747987657785416,
-0.05781937390565872,
0.01844375766813755,
-0.007283997256308794,
0.01815183274447918,
-0.04189079999923706,
-0.03877945616841316,
0.015083467587828636,
0.017221255227923393,
-0.10491017252206802,
-0.08037973195314407,
0.013447987847030163,
-0.022741448134183884,
-0.00965399295091629,
0.01414406206458807,
-0.06049805507063866,
0.015348926186561584,
-0.1292772740125656,
-0.016742104664444923,
0.031431231647729874
] |
PMID:17623656 | In our efforts to develop a disease-modifying osteoarthritis drug, we have discovered MMP13 inhibitors that differ greatly from previous MMP inhibitors; they do not bind to the catalytic zinc ion, they are noncompetitive with respect to substrate binding, and they show extreme selectivity for inhibiting MMP13. | [
-0.09888871759176254,
-0.051182858645915985,
0.001603114535100758,
-0.005437220446765423,
0.011729981750249863,
0.017932938411831856,
-0.09952376782894135,
0.10143952071666718,
0.006389759946614504,
0.013196757063269615,
-0.007294931448996067,
0.06850387901067734,
0.0065838941372931,
0.013715940527617931,
-0.08155707269906998,
0.060495950281620026,
0.030901361256837845,
0.08899068087339401,
0.03948146104812622,
0.08252521604299545,
-0.035599928349256516,
0.012286582961678505,
0.09246371686458588,
-0.05046690255403519,
-0.04431816190481186,
0.03919915109872818,
0.0023926550056785345,
0.0646744892001152,
0.0034435580018907785,
0.056224387139081955,
-0.027682390064001083,
0.06610208004713058,
0.04472727328538895,
-0.04115587845444679,
0.04861878231167793,
0.018568698316812515,
-0.09482267498970032,
-0.04139629006385803,
-0.08062224835157394,
-0.04740244150161743,
0.03934340551495552,
-0.0390302948653698,
0.017568137496709824,
-0.08162710070610046,
0.039502665400505066,
-0.10323301702737808,
-0.07100195437669754,
0.00724969943985343,
-0.07017119228839874,
0.1314736008644104,
0.01358032412827015,
-0.028679700568318367,
-0.005212561227381229,
0.0967785194516182,
-0.016472123563289642,
-0.04867805168032646,
-0.15048162639141083,
0.09302553534507751,
0.013010451570153236,
0.03773289918899536,
0.06062415614724159,
0.03716661036014557,
-0.036016739904880524,
-0.00198550196364522,
0.08912413567304611,
0.008589273318648338,
-0.03572851046919823,
-0.028286321088671684,
-0.06080678850412369,
0.01004725694656372,
-0.07784882932901382,
-0.04104955866932869,
-0.008306053467094898,
0.00024317018687725067,
-0.00015815079677850008,
0.04385820031166077,
0.01272929273545742,
-0.03955598175525665,
0.021036570891737938,
-0.009950496256351471,
0.03369256854057312,
0.04613780230283737,
-0.01688317209482193,
0.12547296285629272,
0.07434927672147751,
0.02788778953254223,
-0.02697843499481678,
0.06766936928033829,
-0.013851266354322433,
0.013401970267295837,
0.011509262956678867,
0.015371997840702534,
-0.0627354085445404,
0.006114312447607517,
-0.033538009971380234,
0.01966237463057041,
-0.060431282967329025,
0.08958393335342407,
-0.08357557654380798,
0.01908891461789608,
0.01864313706755638,
0.06680374592542648,
0.029216237366199493,
-0.07650487869977951,
0.0074421996250748634,
-0.030753320083022118,
0.03170835226774216,
-0.02093137986958027,
-0.002751899417489767,
0.026000268757343292,
0.04643482342362404,
-0.007300451397895813,
0.001349310390651226,
-0.010654590092599392,
0.029283912852406502,
0.05364164710044861,
0.04205968603491783,
-0.00919453427195549,
-0.01734309270977974,
-0.015095854178071022,
-0.008299550972878933,
-0.05706004798412323,
-0.01826605759561062,
-0.025051727890968323,
0.007546599023044109,
0.05075890198349953,
-0.07006275653839111,
1.714253166504897e-33,
-0.0031905919313430786,
-0.044174231588840485,
0.06165982037782669,
-0.005056963302195072,
0.038222990930080414,
-0.009513174183666706,
-0.008433850482106209,
-0.0863763615489006,
-0.05833864584565163,
-0.01953996904194355,
-0.013687553815543652,
0.0025163779500871897,
0.06057518348097801,
-0.03316668048501015,
-0.024794582277536392,
-0.025024527683854103,
0.06409680098295212,
-0.009443704970180988,
0.0879083052277565,
-0.062366727739572525,
0.10947191715240479,
0.01050371490418911,
-0.002020592335611582,
-0.015690039843320847,
-0.015041734091937542,
0.024266447871923447,
-0.028985708951950073,
0.032386694103479385,
0.06283432245254517,
-0.033822935074567795,
-0.022800706326961517,
-0.021522633731365204,
-0.05315094813704491,
-0.037454672157764435,
-0.018475765362381935,
-0.03288701921701431,
-0.033140312880277634,
-0.1022733598947525,
0.00430131983011961,
-0.09153372049331665,
-0.010009297169744968,
-0.007591237314045429,
-0.0014636493287980556,
-0.028917761519551277,
0.07616577297449112,
-0.023604778572916985,
-0.031369321048259735,
0.030300626531243324,
-0.015405925922095776,
-0.027856193482875824,
0.052926044911146164,
0.02659720741212368,
-0.02117164433002472,
0.02013952098786831,
-0.05638928711414337,
0.06887663900852203,
-0.07546991109848022,
0.019629912450909615,
0.052605751901865005,
0.0845469981431961,
-0.027059301733970642,
-0.05733131617307663,
0.0031786132603883743,
0.1267470419406891,
0.02363492175936699,
-0.0233648419380188,
-0.018153691664338112,
-0.02037104032933712,
-0.10387693345546722,
0.11874088644981384,
0.035684842616319656,
-0.02779591828584671,
0.08309771865606308,
0.08467460423707962,
0.0006979440804570913,
-0.004787092562764883,
0.025958633050322533,
0.12604601681232452,
0.04371986910700798,
0.004889760632067919,
-0.006332846824079752,
-0.06068943068385124,
-0.07221108675003052,
0.049977511167526245,
-0.05659199133515358,
-0.07459913939237595,
-0.06810135394334793,
-0.06071776524186134,
0.022326163947582245,
-0.057466644793748856,
0.08647072315216064,
-0.0318438746035099,
-0.09075719118118286,
0.04813391715288162,
-0.0693325474858284,
-3.1002234542617615e-33,
0.02823040261864662,
0.08008113503456116,
0.06043435260653496,
-0.07730937749147415,
-0.05432448908686638,
-0.016515139490365982,
-0.004439656622707844,
-0.08518606424331665,
0.07275974005460739,
-0.015060394071042538,
0.12671959400177002,
-0.05101283639669418,
0.012871084734797478,
-0.10160289704799652,
0.022007020190358162,
0.021749485284090042,
0.022923840209841728,
0.03357063606381416,
-0.02221316285431385,
0.010758833028376102,
0.07725704461336136,
0.04413167014718056,
-0.03533422574400902,
0.051933761686086655,
-0.027361411601305008,
0.01196876261383295,
0.06775469332933426,
0.03162603825330734,
-0.06353812664747238,
0.06190362572669983,
-0.015294637531042099,
0.04298914223909378,
-0.08981338143348694,
-0.1593170315027237,
-0.012973945587873459,
0.01343055721372366,
-0.017505137249827385,
-0.06916453689336777,
-0.03681161627173424,
-0.01632395200431347,
0.05328468233346939,
-0.016493912786245346,
-0.056104645133018494,
0.008712089620530605,
0.05247248709201813,
0.027370715513825417,
-0.015871213749051094,
-0.017533428966999054,
0.08232246339321136,
-0.10218790918588638,
0.0013284031301736832,
0.03745235130190849,
0.04350584000349045,
-0.03523501381278038,
0.08054515719413757,
0.0467405691742897,
0.050074804574251175,
-0.06681422889232635,
0.05613112822175026,
0.00772755965590477,
0.0026122932322323322,
0.06024271249771118,
0.04536335915327072,
-0.07721755653619766,
-0.04054161533713341,
0.08720309287309647,
0.009567463770508766,
-0.03023258037865162,
-0.024232182651758194,
0.006973886862397194,
-0.05047290027141571,
0.0042541977018117905,
0.01902678795158863,
0.03951238468289375,
-0.0315789096057415,
0.012800760567188263,
0.09079904109239578,
-0.003643318312242627,
-0.0403146930038929,
-0.10445135086774826,
0.020829280838370323,
-0.043021541088819504,
-0.010822807438671589,
-0.047057945281267166,
-0.06855885684490204,
0.011028584092855453,
0.013914341107010841,
0.035936519503593445,
-0.010122453793883324,
0.07300923764705658,
-0.0101795494556427,
-0.013413116335868835,
-0.01638088747859001,
0.06533712893724442,
-0.011443285271525383,
-3.217152766410436e-8,
0.023922020569443703,
-0.03537382557988167,
0.01945236325263977,
-0.06773199886083603,
-0.05712922289967537,
0.06084920093417168,
-0.015147121623158455,
0.07314663380384445,
0.0075667863711714745,
0.06561868637800217,
0.05555060878396034,
0.0016438448801636696,
-0.007800323888659477,
-0.037066489458084106,
0.017392171546816826,
-0.0013068413827568293,
-0.0016904736403375864,
-0.04779679700732231,
-0.06514351069927216,
-0.07723888009786606,
-0.008942428044974804,
0.017814766615629196,
0.07204078882932663,
-0.023036237806081772,
0.05816119536757469,
-0.05750018730759621,
-0.07387082278728485,
0.0010339816799387336,
-0.033248547464609146,
-0.0177895650267601,
0.017000893130898476,
0.025219596922397614,
0.04390670359134674,
-0.039245717227458954,
-0.04287084937095642,
0.01762881688773632,
0.06636550277471542,
-0.07037898898124695,
-0.034186918288469315,
0.0796482264995575,
-0.07097863405942917,
0.027013016864657402,
-0.04275892674922943,
-0.01905304379761219,
-0.06355692446231842,
0.000990151660516858,
0.01598096825182438,
0.037605464458465576,
0.0025423045735806227,
0.03431801125407219,
-0.0015494035324081779,
-0.006962097715586424,
-0.0066048577427864075,
-0.13851572573184967,
-0.01699628308415413,
0.0504264272749424,
0.00839119404554367,
0.004770366474986076,
-0.008301324211061,
-0.04037661850452423,
-0.03587355464696884,
-0.12589813768863678,
0.03968643769621849,
0.020766399800777435
] |
PMID:17623656 | By structure-based drug design, we generated an orally active MMP13 inhibitor that effectively reduces cartilage damage in vivo and does not induce joint fibroplasias in a rat model of musculoskeletal syndrome side effects. | [
-0.016177590936422348,
-0.05838928371667862,
0.038495320826768875,
0.02200387232005596,
-0.05297623202204704,
-0.03733215481042862,
-0.06775720417499542,
0.14025811851024628,
-0.0006303155678324401,
0.07038465142250061,
-0.0062645734287798405,
0.10598606616258621,
-0.026129599660634995,
0.03857481852173805,
-0.05400136113166809,
0.021004674956202507,
-0.026492562144994736,
0.13515719771385193,
0.03914270177483559,
0.10530512034893036,
-0.014789157547056675,
0.012534413486719131,
0.034654323011636734,
-0.03936728462576866,
-0.053189460188150406,
0.02297358214855194,
0.05637872591614723,
0.043245743960142136,
-0.02530129998922348,
0.01342262513935566,
-0.0032573204953223467,
0.09988605231046677,
0.0574055016040802,
-0.08000962436199188,
0.019348347559571266,
-0.04521763324737549,
-0.038825105875730515,
-0.025780806317925453,
-0.045798204839229584,
-0.08011926710605621,
-0.02518460713326931,
-0.09114143252372742,
0.07658392190933228,
0.012629271484911442,
0.09926852583885193,
-0.09728647023439407,
-0.05973532795906067,
0.01873687095940113,
0.005165298469364643,
0.20177362859249115,
0.012449165806174278,
0.017841346561908722,
0.08576633781194687,
0.04195651784539223,
-0.03177211433649063,
-0.04234723746776581,
-0.14296813309192657,
0.025957290083169937,
-0.03324766457080841,
0.03232714161276817,
0.013636182062327862,
-0.0121363066136837,
0.007524359505623579,
-0.01506059244275093,
0.04764847829937935,
0.05114541947841644,
0.014490101486444473,
-0.030481461435556412,
-0.06758946925401688,
0.05054814741015434,
-0.04316141828894615,
-0.05248764157295227,
-0.026328016072511673,
0.022381577640771866,
-0.01858859695494175,
0.011005798354744911,
-0.00869659148156643,
0.018746644258499146,
0.05744272843003273,
0.0508439838886261,
0.05816713720560074,
0.03004615381360054,
-0.05493825674057007,
0.06772678345441818,
0.01166777964681387,
0.06941244751214981,
0.027170786634087563,
0.05095876380801201,
-0.048746343702077866,
-0.03109014965593815,
-0.04834318533539772,
0.01634424738585949,
-0.06126423180103302,
-0.002478688256815076,
-0.027127670124173164,
0.016746407374739647,
-0.06057979166507721,
0.0861317366361618,
-0.06190028786659241,
-0.01786632277071476,
0.05410510674118996,
0.030732404440641403,
0.06319133937358856,
-0.033848799765110016,
0.008065728470683098,
-0.06482906639575958,
0.03776828199625015,
-0.04784427583217621,
0.04869457706809044,
-0.009058254770934582,
-0.005407241173088551,
0.014551385305821896,
-0.03425400331616402,
-0.016359832137823105,
0.01576612889766693,
0.05255061760544777,
0.04324711859226227,
0.005419317167252302,
0.015249288640916348,
0.014113031327724457,
0.009436273947358131,
-0.0031859748996794224,
-0.01990359090268612,
-0.028234094381332397,
-0.0769287496805191,
-0.028663385659456253,
-0.023753879591822624,
3.2429646057193253e-34,
-0.047043245285749435,
-0.036624521017074585,
-0.025098776444792747,
0.039217498153448105,
0.03463680297136307,
-0.04880820959806442,
-0.019274264574050903,
-0.06671880930662155,
-0.08547607064247131,
-0.03216070681810379,
-0.002164326375350356,
-0.03262115269899368,
0.07557350397109985,
0.012538864277303219,
0.0318836010992527,
0.05276108905673027,
0.03473425284028053,
-0.025785161182284355,
0.1318187713623047,
-0.09975512325763702,
0.05374867469072342,
0.0322435237467289,
0.026577439159154892,
0.01815095730125904,
-0.0285321231931448,
0.06285282224416733,
-0.02910446561872959,
0.06082531064748764,
0.004285501781851053,
-0.019429504871368408,
-0.03237959370017052,
-0.009484335780143738,
-0.013577703386545181,
-0.0708150640130043,
-0.020281430333852768,
-0.0720297247171402,
-0.08193349838256836,
-0.07378639280796051,
0.009813288226723671,
-0.025437748059630394,
0.015070521272718906,
-0.030676307156682014,
-0.022032586857676506,
-0.0006951560499146581,
0.04938479885458946,
0.003660398768261075,
-0.048121992498636246,
0.012243612669408321,
-0.03680286929011345,
-0.0004322334425523877,
0.0641835555434227,
0.034959349781274796,
0.028313323855400085,
0.07428845763206482,
-0.02506004087626934,
0.010213456116616726,
-0.09620639681816101,
-0.07215230166912079,
-0.02954757958650589,
0.051840584725141525,
-0.02892770990729332,
-0.08515430986881256,
0.009839184582233429,
0.06354855000972748,
-0.026119207963347435,
-0.0032415660098195076,
-0.0023553159553557634,
0.0008021806715987623,
-0.10913518071174622,
0.05850893631577492,
0.054805394262075424,
-0.030646147206425667,
-0.0010271519422531128,
0.07864522188901901,
-0.033322662115097046,
0.0013012518174946308,
0.06715544313192368,
0.1780916005373001,
-0.025958087295293808,
0.04453551024198532,
-0.0003785347507800907,
0.012835327535867691,
-0.06319519132375717,
0.02141779661178589,
0.008597997948527336,
-0.03985395282506943,
-0.07700666785240173,
-0.07366763055324554,
0.02463967353105545,
-0.09477277845144272,
0.0870586559176445,
-0.07088460773229599,
-0.08220626413822174,
0.049475040286779404,
-0.0024182170163840055,
-1.8762585122382785e-33,
0.016216421499848366,
0.09537642449140549,
0.021983308717608452,
-0.0655641257762909,
-0.08638057112693787,
-0.023472044616937637,
0.020524756982922554,
-0.027260327711701393,
0.0702594444155693,
-0.020674709230661392,
0.05142723768949509,
-0.03284437581896782,
-0.052178096026182175,
-0.14374402165412903,
0.08518930524587631,
0.042893484234809875,
0.054739538580179214,
-0.07297073304653168,
-0.05263790860772133,
-0.009366204030811787,
0.10711449384689331,
0.05651908367872238,
-0.001975624356418848,
0.057055555284023285,
0.030966930091381073,
0.016219275072216988,
-0.0214485302567482,
-0.06489262729883194,
-0.009547126479446888,
0.06105067580938339,
-0.029910676181316376,
0.014136083424091339,
-0.00074355787364766,
-0.018134016543626785,
0.04961634427309036,
-0.01010415144264698,
-0.017686430364847183,
-0.040727220475673676,
-0.011848509311676025,
-0.03200283646583557,
0.07260489463806152,
0.04326656833291054,
-0.06800797581672668,
0.001452664379030466,
0.033643364906311035,
-0.014577068388462067,
-0.01036328449845314,
-0.029645323753356934,
0.013320875354111195,
-0.06791194528341293,
-0.052544500678777695,
0.038074955344200134,
0.04184914752840996,
-0.07915539294481277,
0.11125723272562027,
0.009661252610385418,
0.06690890341997147,
-0.06127390265464783,
0.028223199769854546,
0.04295540973544121,
-0.01150124054402113,
0.04306759685277939,
0.03933527320623398,
-0.05117696523666382,
-0.047458626329898834,
0.09504488855600357,
-0.022579608485102654,
-0.019387396052479744,
-0.02671208046376705,
0.025626059621572495,
-0.08640445023775101,
0.019752193242311478,
-0.004609030671417713,
0.07241657376289368,
-0.03755733743309975,
0.05626554414629936,
0.04714665934443474,
-0.012390241958200932,
-0.070745550096035,
-0.09051142632961273,
0.01685361936688423,
-0.07187838107347488,
0.0001383093767799437,
-0.049051765352487564,
-0.02060309797525406,
-0.012284197844564915,
-0.05417468398809433,
0.040837980806827545,
0.030241023749113083,
0.08123115450143814,
0.04575051739811897,
0.0349545031785965,
-0.030308034271001816,
0.08223284780979156,
0.013326105661690235,
-2.8314287803254956e-8,
-0.047085367143154144,
-0.012717299163341522,
-0.011676028370857239,
-0.06828533858060837,
-0.06859169155359268,
0.028006264939904213,
-0.01818523183465004,
0.06104085594415665,
-0.01222725585103035,
0.04105956107378006,
-0.03524816781282425,
0.06215615198016167,
-0.01628970541059971,
0.008783821016550064,
0.0058784871362149715,
0.03954226151108742,
0.03666834905743599,
-0.003970351070165634,
-0.03092130273580551,
-0.033718232065439224,
-0.04906633868813515,
-0.0016836049035191536,
0.047350574284791946,
0.02221434935927391,
0.031752027571201324,
-0.07955779880285263,
-0.03555801883339882,
0.028130272403359413,
-0.042823728173971176,
0.02654217556118965,
0.03904712200164795,
0.022849489003419876,
-0.03881106898188591,
0.0406651645898819,
-0.03934057429432869,
0.028721511363983154,
0.027232317253947258,
-0.0440196767449379,
-0.0771852657198906,
0.10255195945501328,
-0.044475533068180084,
0.08510401099920273,
-0.000055787710152799264,
-0.012867310084402561,
-0.03312723711133003,
0.0030392894987016916,
-0.004704378545284271,
0.017073234543204308,
0.016993248835206032,
-0.0005254640127532184,
-0.042374759912490845,
0.015596305951476097,
-0.031170504167675972,
-0.1005638837814331,
-0.08205161988735199,
0.027394017204642296,
-0.0018915593391284347,
0.02218744158744812,
0.06205916404724121,
-0.07990953326225281,
-0.03613053262233734,
-0.08908817917108536,
0.05052048712968826,
0.022045569494366646
] |
PMID:17623656 | Thus, highly selective inhibition of MMP13 in patients may overcome the major safety and efficacy challenges that have limited previously tested non-selective MMP inhibitors. | [
-0.05268018692731857,
-0.0536932572722435,
0.04616404324769974,
-0.02785954251885414,
-0.0010470536071807146,
0.014456553384661674,
-0.0885486900806427,
0.10451416671276093,
0.009947197511792183,
0.01853855885565281,
0.00875179935246706,
0.019183913245797157,
-0.07936958223581314,
0.009934713132679462,
-0.024271981790661812,
0.08986228704452515,
0.09247534722089767,
0.07412010431289673,
0.08233410120010376,
0.034775156527757645,
-0.06864774227142334,
-0.03153839707374573,
0.04718364030122757,
0.027389822527766228,
0.017010290175676346,
0.06125699728727341,
-0.04311438277363777,
0.052520982921123505,
0.0018974238773807883,
0.02135007455945015,
0.005519163329154253,
0.01697213016450405,
0.012947888113558292,
-0.015442085452377796,
0.04263467341661453,
0.013927383348345757,
-0.09797303378582001,
0.023561356589198112,
-0.0827886238694191,
-0.05516311898827553,
0.04178959131240845,
-0.03890019655227661,
-0.035868268460035324,
-0.06981018930673599,
0.04768839851021767,
-0.1432313472032547,
-0.10635320842266083,
0.009377782233059406,
-0.047731418162584305,
0.13353848457336426,
-0.004327515140175819,
-0.022647090256214142,
-0.030870838090777397,
0.05667310953140259,
0.033078934997320175,
-0.10477592796087265,
-0.06643498688936234,
0.13255256414413452,
0.03986850753426552,
0.05311489477753639,
-0.04014452546834946,
-0.026329271495342255,
-0.005949560087174177,
-0.019421657547354698,
0.11003924161195755,
0.019617704674601555,
-0.05194174498319626,
-0.027707679197192192,
0.02550607919692993,
0.030223749577999115,
-0.05231397598981857,
-0.07055127620697021,
0.010355678386986256,
-0.0033537475392222404,
-0.0005798018537461758,
0.002058908110484481,
-0.015839995816349983,
-0.0005152021767571568,
0.007890081033110619,
0.07045895606279373,
0.03215455263853073,
0.038346391171216965,
0.04004891961812973,
0.014101863838732243,
0.03790765628218651,
-0.013762415386736393,
-0.060952406376600266,
0.05608087405562401,
-0.019764365628361702,
0.020313777029514313,
0.009594852104783058,
0.036234792321920395,
-0.019649747759103775,
0.04473607987165451,
0.02566870115697384,
-0.004424402955919504,
-0.12191450595855713,
0.02989891543984413,
-0.0631042942404747,
-0.019181454554200172,
0.053262315690517426,
0.047046151012182236,
-0.07189087569713593,
-0.038090579211711884,
-0.0167964119464159,
-0.010491236113011837,
0.034907400608062744,
-0.08389417827129364,
0.0016153269680216908,
-0.04264036566019058,
0.04449416697025299,
-0.008782008662819862,
-0.0038874612655490637,
0.006137647666037083,
0.04203231632709503,
0.03683556243777275,
0.01891101524233818,
-0.01865449734032154,
0.06841887533664703,
0.060963962227106094,
0.008671031333506107,
-0.11018072813749313,
0.05862988159060478,
-0.0550113283097744,
0.036198683083057404,
0.10533399879932404,
0.008045247755944729,
-2.6045283690262975e-34,
0.032473791390657425,
-0.05137799680233002,
0.07481782138347626,
0.038771964609622955,
-0.00028109128470532596,
0.00965141411870718,
0.009131252765655518,
-0.07548833638429642,
-0.009705801494419575,
-0.03618285804986954,
0.03356176242232323,
-0.08787893503904343,
0.0425962395966053,
0.03709457814693451,
-0.011702033691108227,
-0.03440931439399719,
0.053648941218853,
0.002545533236116171,
0.11777178943157196,
-0.08419972658157349,
0.07030261307954788,
-0.01766945607960224,
-0.011423260904848576,
-0.036688003689050674,
-0.060743022710084915,
0.07210937142372131,
-0.03658765181899071,
0.11568597704172134,
0.05159388482570648,
0.006665688473731279,
-0.06454549729824066,
0.0024414784274995327,
-0.0331069678068161,
-0.013833942823112011,
-0.0889529213309288,
0.038311105221509933,
-0.03178255259990692,
-0.12378235906362534,
0.04442550241947174,
-0.02393573522567749,
-0.021625809371471405,
0.015331249684095383,
0.024831922724843025,
-0.005680782720446587,
0.05423653498291969,
-0.02994302287697792,
-0.06224525719881058,
-0.060531821101903915,
-0.10326366871595383,
0.017961889505386353,
0.030031325295567513,
-0.05050655081868172,
0.0005473041674122214,
0.06141451373696327,
-0.005341253709048033,
0.07907384634017944,
-0.06904951483011246,
0.036611076444387436,
0.024272026494145393,
0.04005527123808861,
0.01833312027156353,
-0.057026639580726624,
-0.019170990213751793,
0.1104283481836319,
0.024685539305210114,
-0.029380198568105698,
0.0016763083403930068,
-0.014934631064534187,
-0.13976091146469116,
0.05370534956455231,
0.004623457323759794,
-0.026807663962244987,
0.0862334743142128,
0.050221025943756104,
0.005211129784584045,
-0.01876210793852806,
0.03836233168840408,
0.1276063621044159,
-0.0012758265947923064,
0.028000017628073692,
0.023082252591848373,
-0.030421728268265724,
-0.10302942246198654,
0.00037046964280307293,
-0.031648486852645874,
-0.04840433597564697,
-0.05922141671180725,
-0.06434354931116104,
0.0030407949816435575,
-0.043120112270116806,
0.10588530451059341,
-0.009846845641732216,
-0.042852479964494705,
0.1199667751789093,
-0.048131924122571945,
-8.668030139761276e-34,
0.027102457359433174,
0.04216546565294266,
0.07071109861135483,
-0.062129274010658264,
-0.07878566533327103,
0.026800990104675293,
0.03344741836190224,
-0.07473679631948471,
0.1008465364575386,
-0.0053979200311005116,
0.08941561728715897,
-0.06339915841817856,
0.008274347521364689,
-0.08340241014957428,
-0.013524495996534824,
0.001593859982676804,
-0.011656664311885834,
0.014553387649357319,
0.010199442505836487,
0.006853618659079075,
0.07861610502004623,
-0.012823821045458317,
-0.043033666908741,
0.07545826584100723,
-0.06722286343574524,
0.0003493251570034772,
-0.010212142020463943,
-0.03817369416356087,
-0.012983160093426704,
0.037972915917634964,
-0.01802249066531658,
0.06734612584114075,
-0.0671529695391655,
-0.12682324647903442,
0.05352025106549263,
-0.027493825182318687,
-0.006376182194799185,
-0.04282781481742859,
-0.04180242866277695,
-0.04218512773513794,
0.040569156408309937,
0.047306448221206665,
-0.050246745347976685,
-0.03868786618113518,
-0.002304623369127512,
0.03125852346420288,
0.10512953251600266,
-0.029261305928230286,
0.05893801525235176,
-0.00456901453435421,
-0.0925295501947403,
-0.011541806161403656,
-0.0007332603563554585,
0.010992517694830894,
0.02646886371076107,
-0.0046045249328017235,
0.03099309466779232,
-0.032951243221759796,
0.03228425979614258,
0.0707680955529213,
-0.010622975416481495,
0.03465956449508667,
0.006202695891261101,
-0.03087216429412365,
0.017230741679668427,
0.16628290712833405,
0.0077166929841041565,
0.025218117982149124,
0.038071177899837494,
-0.013354883529245853,
-0.06057049706578255,
0.004203618969768286,
-0.04183331876993179,
0.032611023634672165,
-0.058435194194316864,
-0.02057219110429287,
0.02472865767776966,
-0.03277372196316719,
-0.012841914780437946,
-0.12100641429424286,
0.011282219551503658,
-0.03418227657675743,
-0.08888569474220276,
-0.07163012027740479,
0.01362187322229147,
-0.0040255882777273655,
-0.001555988215841353,
-0.006842539645731449,
-0.019802816212177277,
0.005026138853281736,
-0.012914353050291538,
-0.04401713237166405,
-0.006911400705575943,
0.028927680104970932,
-0.05262608453631401,
-2.4192098990738486e-8,
0.019089937210083008,
-0.031340062618255615,
0.048470497131347656,
-0.02759457565844059,
-0.009942872449755669,
0.013569026254117489,
-0.04737507924437523,
0.06488844752311707,
-0.03427395969629288,
0.07449522614479065,
0.05781257152557373,
-0.0021099054720252752,
-0.03600858524441719,
-0.06602544337511063,
0.04146309942007065,
0.011172584258019924,
0.020105862990021706,
0.007209321949630976,
-0.005095058586448431,
-0.034320831298828125,
0.0024776128120720387,
0.000525116513017565,
0.09782276302576065,
-0.024936171248555183,
0.02677259035408497,
-0.016807597130537033,
-0.0022919101174920797,
0.08537040650844574,
0.06228785216808319,
-0.07162515074014664,
0.007809618022292852,
-0.0030047004111111164,
0.04259685426950455,
0.014777068980038166,
-0.055271293967962265,
0.06811165064573288,
0.06919606775045395,
-0.013750925660133362,
-0.006187158636748791,
0.07183635979890823,
-0.050083864480257034,
0.007966781966388226,
-0.02907441556453705,
-0.03215309605002403,
-0.09325126558542252,
0.037479300051927567,
0.015258085913956165,
0.007018158212304115,
-0.01666124351322651,
-0.00613444484770298,
-0.01688273809850216,
0.007098196540027857,
0.003422046545892954,
-0.032918691635131836,
-0.02287820354104042,
0.05187172070145607,
0.05288289487361908,
0.027110973373055458,
0.044703301042318344,
-0.08407410979270935,
-0.015695257112383842,
-0.10951243340969086,
-0.0031388569623231888,
-0.00011259024176979437
] |
PMID:17623656 | MMP13 inhibitors such as the ones described here will help further define the role of this protease in arthritis and other diseases and may soon lead to drugs that safely halt cartilage damage in patients. | [
-0.05414293333888054,
-0.06601841002702713,
0.0056893122382462025,
-0.010019343346357346,
0.010081721469759941,
0.014014828950166702,
-0.05734453350305557,
0.14502373337745667,
0.006564313545823097,
0.0465918704867363,
0.014398135244846344,
0.1360274702310562,
-0.05023295059800148,
0.005432133097201586,
-0.10824735462665558,
0.06296303868293762,
0.013675431720912457,
0.08506526798009872,
-0.01923108659684658,
0.033146318048238754,
-0.03023657761514187,
0.012950897216796875,
0.08382289111614227,
-0.014216391369700432,
-0.05271795392036438,
0.04451596364378929,
0.010632909834384918,
0.04774438589811325,
0.004997428506612778,
0.007264160085469484,
-0.01657210849225521,
0.057887669652700424,
0.03288908302783966,
-0.04891796037554741,
0.046404894441366196,
0.013821564614772797,
-0.08015742897987366,
-0.02524290606379509,
-0.07646501809358597,
-0.05793715640902519,
0.03991769999265671,
-0.09087207168340683,
0.024870114400982857,
-0.05090102553367615,
0.05664115026593208,
-0.0726822093129158,
-0.07509177923202515,
0.02987004444003105,
0.002575934398919344,
0.1540767103433609,
0.04226042702794075,
0.002025151625275612,
0.05087575316429138,
0.07237417995929718,
-0.022364195436239243,
-0.07549551874399185,
-0.1136961579322815,
0.04247122257947922,
0.027516769245266914,
0.043664004653692245,
0.013200259767472744,
0.04210442304611206,
-0.034051597118377686,
-0.017303606495261192,
0.06285999715328217,
-0.03519858419895172,
0.034556519240140915,
-0.03989322483539581,
-0.06486746668815613,
0.07157451659440994,
-0.040079083293676376,
-0.0692749097943306,
-0.012303953990340233,
0.031245756894350052,
0.004061925690621138,
0.05617788806557655,
-0.03604254126548767,
-0.08321575075387955,
0.04029323533177376,
0.029706597328186035,
0.06134512647986412,
0.03839188069105148,
-0.0009328020387329161,
0.0604320727288723,
0.03723415359854698,
0.021757546812295914,
0.007289363536983728,
0.023494096472859383,
-0.018283164128661156,
-0.04798033460974693,
-0.03123418428003788,
-0.0185238029807806,
-0.06918177008628845,
0.019773036241531372,
-0.024889735504984856,
0.00738161988556385,
-0.08522602915763855,
0.035191137343645096,
-0.06242469325661659,
-0.012429873459041119,
-0.024564001709222794,
0.022315531969070435,
0.041356246918439865,
-0.10632062703371048,
-0.05171483755111694,
-0.06174967437982559,
0.01973825879395008,
-0.031206408515572548,
0.04911467432975769,
0.021956173703074455,
0.031002890318632126,
-0.009322662837803364,
-0.012156425043940544,
-0.017318766564130783,
0.011280905455350876,
0.09663178771734238,
0.007665663957595825,
0.014118175022304058,
-0.015547911636531353,
0.008596369065344334,
-0.005098642781376839,
-0.05327926203608513,
-0.01613062620162964,
-0.03182925283908844,
-0.027272488921880722,
0.013371728360652924,
-0.05351684242486954,
-6.990885883502774e-35,
-0.0014506032457575202,
-0.0601470060646534,
0.02626851573586464,
0.017172863706946373,
0.02185581624507904,
-0.02854240871965885,
-0.05034473165869713,
-0.11318492144346237,
-0.029649853706359863,
-0.03133545443415642,
0.003387246048077941,
-0.02306712046265602,
0.0954131931066513,
-0.02166476845741272,
-0.040493194013834,
-0.009938121773302555,
0.04670010879635811,
-0.03043830208480358,
0.07599683851003647,
-0.05034888535737991,
0.08371109515428543,
0.011677530594170094,
0.01643608696758747,
-0.0048627364449203014,
-0.025952035561203957,
0.06040680408477783,
-0.010737466625869274,
0.07132361084222794,
0.08058447390794754,
-0.015989914536476135,
-0.01460263691842556,
0.012577109970152378,
-0.08169353753328323,
-0.04034406319260597,
-0.033834174275398254,
-0.015561698004603386,
-0.08961756527423859,
-0.1066865399479866,
-0.02735414355993271,
-0.015734272077679634,
-0.03850496560335159,
-0.03514419496059418,
-0.03121965378522873,
-0.04059561342000961,
0.10590479522943497,
-0.060886088758707047,
-0.03618165850639343,
-0.004310084506869316,
-0.026065712794661522,
0.028200684115290642,
0.07386861741542816,
0.01838248036801815,
-0.013183321803808212,
0.04040418565273285,
-0.009127612225711346,
0.03410078585147858,
-0.05104668065905571,
-0.005566369276493788,
0.026944385841488838,
0.019338425248861313,
-0.012935073114931583,
-0.08496593683958054,
-0.009769530035555363,
0.06083238869905472,
-0.0018060861621052027,
-0.030424587428569794,
0.00689329206943512,
-0.005249223206192255,
-0.09155340492725372,
0.048191942274570465,
0.0006888751522637904,
-0.014573181048035622,
0.057677026838064194,
0.10603900998830795,
-0.029213089495897293,
0.0353243313729763,
0.06595126539468765,
0.17269833385944366,
0.019252903759479523,
0.02335485816001892,
-0.03960185870528221,
-0.057666387408971786,
-0.06684263050556183,
0.0623331181704998,
-0.03155180811882019,
-0.046317655593156815,
-0.08804919570684433,
-0.08244950324296951,
-0.01054706797003746,
-0.07376987487077713,
0.08869529515504837,
-0.048051316291093826,
-0.11956620216369629,
0.08851360529661179,
-0.0498502142727375,
-2.590212454954465e-33,
0.03600796312093735,
0.06263156980276108,
0.011286847293376923,
-0.05238818749785423,
-0.04178069531917572,
0.005160108674317598,
0.00242790998890996,
-0.03185800462961197,
0.06761155277490616,
-0.05115216597914696,
0.05615520849823952,
-0.06767561286687851,
-0.02884347178041935,
-0.0779459998011589,
0.032665204256772995,
0.011243456043303013,
0.03844017535448074,
-0.003748017828911543,
-0.059735413640737534,
0.0422021746635437,
0.07317410409450531,
0.11497572809457779,
-0.011522946879267693,
0.06042510271072388,
-0.019926248118281364,
0.02538399025797844,
0.022384226322174072,
-0.03539935499429703,
-0.058988433331251144,
0.07873820513486862,
0.026496605947613716,
-0.0035764039494097233,
-0.02463384158909321,
-0.10081440955400467,
0.002349341521039605,
0.006027041003108025,
0.022476810961961746,
-0.057683322578668594,
-0.02233772724866867,
-0.030228765681385994,
0.07295592129230499,
0.02502852864563465,
-0.016368692740797997,
0.009090475738048553,
0.032083798199892044,
0.0022979944478720427,
-0.016442252323031425,
-0.02525404840707779,
0.04716794937849045,
-0.05526683107018471,
-0.010027533397078514,
0.04791921749711037,
0.042375966906547546,
-0.051138557493686676,
0.09567811340093613,
0.005672889295965433,
0.04736951366066933,
-0.09669981151819229,
0.0314878448843956,
0.06599066406488419,
0.0026652789674699306,
0.08487904816865921,
0.06529722362756729,
-0.024871762841939926,
-0.02243996411561966,
0.1390347182750702,
-0.010905302129685879,
-0.036663249135017395,
0.01873900555074215,
0.023201532661914825,
-0.03653709217905998,
-0.017410973086953163,
-0.02819567546248436,
0.0804285928606987,
-0.039830684661865234,
-0.02866050973534584,
0.057220663875341415,
-0.01217725221067667,
-0.02260529063642025,
-0.11679686605930328,
-0.019607307389378548,
-0.07310547679662704,
-0.04561777412891388,
-0.03038100153207779,
-0.024081062525510788,
-0.020876601338386536,
-0.04176188260316849,
0.055422455072402954,
0.031388092786073685,
0.06636994332075119,
-0.003222057595849037,
0.026693493127822876,
-0.038712382316589355,
0.08964792639017105,
0.019919751212000847,
-2.7899032417622038e-8,
0.01594374142587185,
-0.0637488067150116,
0.046208981424570084,
-0.06007219851016998,
-0.04926352947950363,
0.01617022044956684,
-0.011896928772330284,
0.1004858911037445,
-0.0236720759421587,
0.05816660448908806,
0.03661435842514038,
0.06695511192083359,
-0.01319893915206194,
-0.06027128919959068,
0.04627474397420883,
0.059917252510786057,
0.04165663942694664,
-0.02046528458595276,
-0.06533382087945938,
-0.10515588521957397,
-0.020718565210700035,
-0.028416911140084267,
0.08931540697813034,
-0.002042088657617569,
-0.001635081833228469,
-0.03644053265452385,
-0.016430078074336052,
0.05063692480325699,
-0.07014916092157364,
-0.021111471578478813,
0.013070307672023773,
0.046745944768190384,
0.010316184721887112,
-0.023712441325187683,
-0.04452566057443619,
0.10204791277647018,
0.06599531322717667,
-0.061442166566848755,
-0.040973175317049026,
0.06556820869445801,
-0.05450090765953064,
0.048440564423799515,
-0.017459634691476822,
-0.0030863992869853973,
-0.047142643481492996,
-0.008331541903316975,
0.01488927286118269,
0.04647894948720932,
-0.01933404803276062,
0.005473030731081963,
-0.06170981377363205,
0.009362439624965191,
-0.008382802829146385,
-0.06446468830108643,
-0.08208668231964111,
0.05735379830002785,
0.015434470027685165,
0.0063764541409909725,
0.05492245405912399,
-0.039560217410326004,
-0.03718707337975502,
-0.09862886369228363,
0.07444849610328674,
0.00817682035267353
] |
PMID:16420030 | The synthesis and matrix metalloproteinase (MMP) inhibitory activity of a series of gamma-keto carboxylic acids are described. | [
-0.009584726765751839,
-0.059299666434526443,
-0.006848655175417662,
0.030357031151652336,
-0.031563445925712585,
0.12608584761619568,
-0.0466373972594738,
-0.004639595281332731,
0.04191332310438156,
-0.0003701628011185676,
0.023030182346701622,
-0.03987736999988556,
0.012155355885624886,
0.014199825935065746,
-0.0755295604467392,
0.059975579380989075,
0.03180363401770592,
0.05457605794072151,
0.0416991263628006,
0.01670040376484394,
-0.057614706456661224,
-0.03882277384400368,
-0.03149709850549698,
-0.03331423178315163,
-0.022026199847459793,
0.10334257781505585,
0.0538894347846508,
-0.017808087170124054,
-0.1333586424589157,
-0.024164706468582153,
-0.029198601841926575,
-0.05393781140446663,
0.05419561266899109,
-0.025573788210749626,
0.06967528909444809,
-0.005597921088337898,
-0.11506646871566772,
-0.027898374944925308,
-0.048852160573005676,
-0.042447078973054886,
0.05202661454677582,
-0.05402066931128502,
0.015822816640138626,
-0.09095562994480133,
0.01836557313799858,
-0.06112531200051308,
-0.009000210091471672,
-0.03143974766135216,
0.02126505598425865,
0.03340793773531914,
-0.024426717311143875,
-0.050220172852277756,
0.0024896045215427876,
0.012371977791190147,
-0.06667719036340714,
-0.0915951281785965,
-0.0904683843255043,
0.04813535511493683,
0.05045836418867111,
0.04980028048157692,
0.02238483354449272,
0.03356349840760231,
0.020663000643253326,
-0.011267856694757938,
0.024291861802339554,
-0.04630197957158089,
0.00029173798975534737,
-0.023088684305548668,
0.0032183912117034197,
0.004601639695465565,
-0.07942145317792892,
-0.07009280472993851,
-0.02057858370244503,
0.028267258778214455,
-0.05660690739750862,
-0.013576364144682884,
-0.01844293251633644,
-0.03262065723538399,
0.1078839972615242,
-0.013214962556958199,
0.07543881237506866,
0.04779035598039627,
0.016772225499153137,
0.01808864250779152,
0.03292044252157211,
0.04432555288076401,
0.06240455061197281,
0.10835886746644974,
0.03241999074816704,
-0.012450072914361954,
0.014035049825906754,
-0.028033532202243805,
-0.006349546369165182,
-0.0028250005561858416,
-0.025602491572499275,
-0.005041639786213636,
-0.05617218837141991,
0.03695645183324814,
-0.0210602805018425,
-0.011745315976440907,
0.017133213579654694,
0.0002272562705911696,
-0.037959009408950806,
-0.027053503319621086,
-0.07960307598114014,
-0.0011148962657898664,
-0.032348498702049255,
0.012047921307384968,
0.03913137689232826,
-0.002585317473858595,
0.031163427978754044,
-0.011272890493273735,
-0.05804797261953354,
0.009818279184401035,
0.019657406955957413,
0.046900298446416855,
0.0970543771982193,
-0.08406449854373932,
0.011365201324224472,
-0.0016816933639347553,
0.011706700548529625,
-0.056295957416296005,
0.03634835034608841,
0.02477625384926796,
0.011211481876671314,
0.051659733057022095,
-0.05876357853412628,
-1.708835606915545e-33,
0.04218100383877754,
0.01983872428536415,
0.0993678942322731,
-0.00378278736025095,
0.044484760612249374,
-0.023571722209453583,
-0.017401713877916336,
-0.025621524080634117,
0.0528782419860363,
-0.04028167575597763,
-0.07057695090770721,
-0.015234224498271942,
0.06715619564056396,
-0.05599940940737724,
0.028438156470656395,
0.028002062812447548,
0.008463616482913494,
-0.03939095884561539,
0.0885176956653595,
-0.08109575510025024,
-0.031970519572496414,
0.04711177200078964,
0.00952277984470129,
0.018512383103370667,
-0.016947677358984947,
0.047867301851511,
-0.0850054994225502,
-0.04635927453637123,
0.09848365932703018,
-0.007625090889632702,
-0.019309721887111664,
0.012833944521844387,
-0.06356531381607056,
0.08436977118253708,
0.030647441744804382,
-0.03573072701692581,
-0.007139032240957022,
-0.06377790123224258,
0.06659761816263199,
0.025774948298931122,
-0.03816419094800949,
-0.04322835057973862,
-0.05435531958937645,
-0.05921132117509842,
-0.05366148054599762,
-0.0193948931992054,
-0.0586373396217823,
0.023241834715008736,
-0.03223525732755661,
-0.002318466315045953,
0.08566956222057343,
-0.003984397742897272,
0.024415744468569756,
-0.02759302407503128,
-0.016530746594071388,
0.1481785923242569,
-0.09071895480155945,
0.02404812164604664,
0.04248987138271332,
0.04728046432137489,
-0.06421872228384018,
0.000661310856230557,
0.0024338257499039173,
0.04057084769010544,
-0.03665239363908768,
-0.04722616821527481,
-0.07046887278556824,
-0.03506060689687729,
-0.02419949136674404,
0.04678645357489586,
0.010597259737551212,
-0.005952865816652775,
0.15393516421318054,
0.04034892097115517,
0.018754232674837112,
0.03413483500480652,
-0.0034782560542225838,
0.06247015669941902,
-0.01567978970706463,
0.11921799182891846,
0.040396906435489655,
0.011734028346836567,
0.02770826779305935,
-0.07082370668649673,
0.008768359199166298,
0.0007860903861001134,
-0.03861824423074722,
-0.028739245608448982,
0.05335695296525955,
-0.011450822465121746,
0.0003372603969182819,
0.008575981482863426,
-0.041375454515218735,
0.10354311764240265,
-0.033242106437683105,
-1.6369107810085754e-33,
0.17917367815971375,
-0.09380325675010681,
0.09716082364320755,
-0.0314868800342083,
0.016767671331763268,
-0.0013106121914461255,
-0.007979664951562881,
-0.07992138713598251,
0.09938954561948776,
0.04367478936910629,
0.09667950123548508,
-0.012337910011410713,
0.04723784327507019,
-0.009071912616491318,
0.0289972722530365,
-0.07982217520475388,
0.001039727940224111,
0.08095645159482956,
-0.029397331178188324,
-0.047393616288900375,
-0.0010383392218500376,
0.021600399166345596,
-0.0199186522513628,
0.04599669575691223,
-0.02456372231245041,
-0.025734465569257736,
-0.06743226945400238,
-0.001451142132282257,
0.08184211701154709,
0.09060437977313995,
0.0379943884909153,
0.015351258218288422,
-0.024776779115200043,
-0.08143803477287292,
0.07422614097595215,
0.04083770886063576,
0.005223819985985756,
0.011796548031270504,
0.010262641124427319,
0.10933032631874084,
-0.06335077434778214,
0.034216031432151794,
-0.025034058839082718,
-0.009350289590656757,
0.04930049926042557,
0.10520290583372116,
0.059350479394197464,
-0.023621341213583946,
-0.009928585961461067,
-0.11926280707120895,
-0.02787761390209198,
-0.024849798530340195,
-0.10625919699668884,
-0.03128145635128021,
-0.03417219966650009,
0.1009279116988182,
0.02118910662829876,
-0.00880196038633585,
0.028651541098952293,
0.0410069040954113,
-0.06820303946733475,
-0.06910032033920288,
0.07816455513238907,
-0.10484949499368668,
-0.050710633397102356,
0.09955532848834991,
0.04490870237350464,
0.018803671002388,
0.048492543399333954,
-0.06503267586231232,
0.011669965460896492,
-0.03188711777329445,
-0.007672464940696955,
0.0700664222240448,
0.03134750574827194,
-0.04454052075743675,
-0.023335890844464302,
-0.006953344214707613,
0.04109477624297142,
-0.10415937006473541,
0.040423449128866196,
-0.006887695286422968,
-0.045193541795015335,
-0.05115140601992607,
-0.011833665892481804,
0.0005576326511800289,
-0.018719512969255447,
0.048837970942258835,
-0.015215776860713959,
-0.010276165790855885,
-0.031440507620573044,
-0.03899262472987175,
0.0021346553694456816,
0.13542033731937408,
0.006165774539113045,
-2.6160945409969827e-8,
0.025777483358979225,
-0.016502855345606804,
0.0023667768109589815,
-0.07200761139392853,
0.005640588700771332,
0.03183945268392563,
-0.01673414185643196,
0.03387721627950668,
0.10378658771514893,
-0.06331612169742584,
0.020864689722657204,
-0.012531504034996033,
-0.04886217042803764,
0.015185479074716568,
-0.08322319388389587,
0.012463740073144436,
-0.03009936772286892,
-0.012175630778074265,
0.014157690107822418,
0.030184298753738403,
0.02787471003830433,
-0.011803223751485348,
0.035220667719841,
-0.017115743830800056,
-0.060274895280599594,
-0.09236246347427368,
0.013182446360588074,
0.06846350431442261,
-0.07766277343034744,
-0.03542749211192131,
-0.07188640534877777,
0.07630228996276855,
0.05571754276752472,
0.008677604608237743,
-0.0421610064804554,
-0.04816048964858055,
0.0328291580080986,
0.010173140093684196,
-0.002488757949322462,
0.03347259759902954,
0.01491980068385601,
-0.0642586201429367,
0.0013954034075140953,
-0.032693784683942795,
-0.05575890839099884,
0.05342420935630798,
-0.00823591835796833,
0.021695075556635857,
-0.05345628410577774,
-0.017100928351283073,
-0.01779334619641304,
0.06171761825680733,
-0.08728139102458954,
-0.030668197199702263,
0.029243728145956993,
0.0008514502551406622,
0.047459445893764496,
-0.07936707139015198,
-0.03635753318667412,
-0.10094768553972244,
-0.05651303753256798,
-0.05959807336330414,
0.10089291632175446,
-0.02606312185525894
] |
PMID:16420030 | Among nine MMP isozymes tested, compound 1j displays selective inhibition of MMP-2, -9, and -12 with IC(50) values between 0.20 and 1.51 microuM, and in male golden Syrian hamsters, it shows protection against PPE-induced emphysema. | [
0.025532729923725128,
0.04923078790307045,
0.07808587700128555,
-0.01096288301050663,
0.05021422728896141,
0.04998963698744774,
0.055746037513017654,
0.11438172310590744,
-0.014533977955579758,
0.07749263942241669,
0.045269519090652466,
0.04052632674574852,
0.004212454427033663,
0.08243492990732193,
-0.03799320384860039,
0.0654182955622673,
0.0036573512479662895,
0.07236107438802719,
0.007081133779138327,
0.0061356560327112675,
-0.010016905143857002,
-0.0037727090530097485,
0.017712168395519257,
-0.10907719284296036,
0.053202882409095764,
0.010903882794082165,
0.04752510413527489,
0.04315951094031334,
-0.022851239889860153,
0.012197132222354412,
0.027609365060925484,
-0.025134628638625145,
0.060010213404893875,
-0.02237880788743496,
0.0015277790371328592,
-0.023822808638215065,
-0.014236683957278728,
0.05921509116888046,
-0.0685281977057457,
0.05396611616015434,
0.06235402077436447,
-0.032275035977363586,
-0.029814422130584717,
-0.04725446179509163,
-0.011586633510887623,
-0.04522087052464485,
-0.022037090733647346,
0.017863500863313675,
-0.05960926413536072,
0.07400070130825043,
0.03561067581176758,
-0.04020105302333832,
-0.06594648212194443,
0.08604133874177933,
0.016727721318602562,
-0.10650045424699783,
-0.10232124477624893,
0.05779566615819931,
-0.06668287515640259,
-0.06397322565317154,
-0.06166832521557808,
-0.004719720222055912,
-0.04067164286971092,
0.004263045731931925,
0.04682157561182976,
-0.051597438752651215,
0.06869161874055862,
0.01459593791514635,
0.0401143878698349,
-0.017354097217321396,
0.007505147252231836,
-0.04621541127562523,
-0.017057720571756363,
-0.02534126304090023,
-0.08788828551769257,
0.056078266352415085,
-0.128082275390625,
-0.07932346314191818,
0.09371708333492279,
-0.0017534297658130527,
0.03432102128863335,
0.012457315810024738,
0.08370606601238251,
-0.0025666626170277596,
0.0713372528553009,
0.004945020657032728,
-0.028140563517808914,
0.08563441783189774,
-0.03495103493332863,
-0.023097919300198555,
0.0167002584785223,
-0.017129315063357353,
-0.014750881120562553,
0.03750850260257721,
0.022013472393155098,
-0.01031433790922165,
-0.010963124223053455,
0.06299901753664017,
-0.03961097076535225,
0.024781031534075737,
0.03691596910357475,
0.04165065288543701,
-0.0509890578687191,
-0.03425679728388786,
-0.049589406698942184,
-0.006881995592266321,
0.02593255415558815,
-0.02914470247924328,
0.012190528213977814,
0.0032334032002836466,
-0.018731623888015747,
0.007465537637472153,
-0.01803482696413994,
0.008874909020960331,
0.04279007390141487,
0.05781874060630798,
0.0682641938328743,
0.017457526177167892,
0.048268772661685944,
-0.05512549355626106,
-0.04990452900528908,
-0.013157428242266178,
0.004900273401290178,
0.018020518124103546,
-0.018724903464317322,
0.07092329114675522,
-0.002778253285214305,
-1.7154072861439886e-34,
0.0003972634149249643,
-0.010512138716876507,
0.0545416884124279,
0.016345925629138947,
0.0215581227093935,
0.03243241086602211,
-0.03964586183428764,
-0.056063856929540634,
0.026170972734689713,
-0.016042985022068024,
-0.09594414383172989,
-0.07735884189605713,
0.028624141588807106,
-0.022680874913930893,
-0.006079030688852072,
0.003944102209061384,
0.01731346733868122,
-0.00464825052767992,
0.10094112157821655,
-0.06838366389274597,
-0.09033378958702087,
-0.01695982553064823,
-0.007747423369437456,
-0.037662409245967865,
0.02916833758354187,
0.049679387360811234,
0.038622453808784485,
0.05673046410083771,
0.018351390957832336,
-0.01436441857367754,
-0.036911167204380035,
0.002295426558703184,
-0.1403501033782959,
-0.02296372875571251,
-0.0360092855989933,
0.031938474625349045,
-0.029074758291244507,
-0.02815316803753376,
-0.03277973830699921,
-0.04970647394657135,
-0.019568398594856262,
-0.039360664784908295,
0.0009279117221012712,
-0.0595426931977272,
0.07134146243333817,
-0.08394753187894821,
-0.1536025106906891,
-0.033765602856874466,
0.010574555024504662,
0.03202645853161812,
0.04973712936043739,
0.0024366790894418955,
0.028956562280654907,
0.007022400386631489,
-0.04717890918254852,
0.02074342593550682,
-0.017866967245936394,
0.0740714967250824,
-0.029751673340797424,
0.0921890065073967,
0.022536998614668846,
0.005568226799368858,
0.0006614077719859779,
0.02497839368879795,
0.01668771542608738,
0.036983173340559006,
-0.12983837723731995,
-0.07233017683029175,
-0.06005748361349106,
0.11528056114912033,
0.02431108057498932,
-0.06333586573600769,
0.06988030672073364,
-0.08338834345340729,
-0.007318422198295593,
-0.023860516026616096,
0.03298214450478554,
0.18199265003204346,
0.01646355725824833,
0.028200501576066017,
0.019845888018608093,
0.013792366720736027,
-0.05415220931172371,
0.01639441028237343,
-0.11978679895401001,
-0.04958365857601166,
0.001381228561513126,
0.050161514431238174,
0.04199698939919472,
-0.029676295816898346,
0.18062472343444824,
0.015061607584357262,
-0.0926487073302269,
0.07979344576597214,
0.007866444997489452,
-1.3837423586200715e-33,
0.010567840188741684,
-0.025202849879860878,
0.05118817463517189,
-0.04012727737426758,
-0.05394892394542694,
0.15174421668052673,
0.019669637084007263,
-0.04350421577692032,
0.026044251397252083,
-0.018972035497426987,
0.08076544851064682,
-0.005686817225068808,
0.027565252035856247,
-0.046303488314151764,
0.01772681437432766,
-0.04630883038043976,
-0.0022415511775761843,
0.09253979474306107,
0.004872355610132217,
0.030788516625761986,
-0.0018193104770034552,
0.020242782309651375,
0.028806842863559723,
0.13502998650074005,
-0.021083680912852287,
-0.041739802807569504,
0.03618689253926277,
-0.021351508796215057,
0.003504742868244648,
0.03420637547969818,
0.04012215882539749,
0.02679607830941677,
-0.07401517778635025,
-0.017788134515285492,
0.045513853430747986,
-0.0901322066783905,
0.009595604613423347,
0.049653973430395126,
-0.06368615478277206,
0.024140937253832817,
-0.018210403621196747,
-0.0035145902074873447,
-0.02842049114406109,
0.04621446505188942,
0.024787919595837593,
0.07308932393789291,
0.03542834520339966,
-0.0855376124382019,
0.01559115294367075,
-0.08590447902679443,
-0.035252269357442856,
0.005747759714722633,
-0.04783494025468826,
-0.05597496032714844,
0.042280666530132294,
0.012794768437743187,
-0.06164630502462387,
0.0008994126110337675,
0.035276543349027634,
0.04236750304698944,
-0.023580027744174004,
0.007476992905139923,
-0.01907210238277912,
-0.04740524664521217,
-0.02667992375791073,
0.040337614715099335,
-0.027386799454689026,
0.012670391239225864,
0.029499834403395653,
-0.04243575036525726,
0.04583548381924629,
0.0024251455906778574,
-0.03219098970293999,
-0.012845131568610668,
-0.021238116547465324,
-0.06911896169185638,
0.030734563246369362,
0.025220906361937523,
0.012634595856070518,
-0.05704553797841072,
0.048005610704422,
-0.046952132135629654,
-0.11066608875989914,
-0.023981161415576935,
-0.02137031964957714,
-0.04460684582591057,
0.03037334606051445,
0.0591466948390007,
-0.034806519746780396,
-0.00619871960952878,
-0.00752193434163928,
0.048984345048666,
-0.11623168736696243,
0.042584795504808426,
0.023390261456370354,
-3.2827621510023164e-8,
0.04077436029911041,
-0.0945957824587822,
0.021050982177257538,
-0.043919239193201065,
-0.07880302518606186,
0.06269372254610062,
-0.049100253731012344,
0.04870765283703804,
0.033440493047237396,
0.03721901401877403,
0.042235977947711945,
0.02201039344072342,
0.007084165699779987,
0.06663545966148376,
0.036403197795152664,
-0.04229362681508064,
-0.011256758123636246,
0.02709224447607994,
0.007191103417426348,
0.02060679905116558,
-0.021220818161964417,
0.029816891998052597,
0.028362203389406204,
-0.019099736586213112,
-0.007257270161062479,
-0.01654607430100441,
0.022684037685394287,
0.1077098548412323,
0.059999190270900726,
-0.034148577600717545,
0.014261243864893913,
0.02814844809472561,
-0.03806238994002342,
0.009709524922072887,
-0.046260904520750046,
0.03890276700258255,
0.10829296708106995,
0.006685322150588036,
0.010044312104582787,
0.01824984699487686,
-0.06255601346492767,
-0.0730363056063652,
-0.03514421358704567,
-0.028612369671463966,
-0.005525047890841961,
0.0340406596660614,
0.02766222134232521,
0.001900712144561112,
-0.10937804728746414,
-0.06777387857437134,
-0.011879829689860344,
0.054192498326301575,
-0.01315914187580347,
-0.11605963855981827,
-0.12414592504501343,
-0.02984202280640602,
-0.05508679524064064,
-0.043488554656505585,
0.006251828745007515,
-0.09587199240922928,
0.03449830785393715,
-0.1027269959449768,
-0.01891360804438591,
-0.01957523450255394
] |
PMID:9548812 | The membrane-type 1 matrix metalloproteinase (MT1-MMP) has been reported to mediate the activation of pro-gelatinase A (proMMP-2), which is associated with tumor proliferation and metastasis. | [
-0.05538122355937958,
-0.051207710057497025,
-0.03139492869377136,
0.030233509838581085,
-0.019226882606744766,
0.0019754525274038315,
0.04784105345606804,
0.07685702294111252,
-0.004994484130293131,
0.0011672192486003041,
-0.006886376067996025,
0.03625097498297691,
0.030097007751464844,
0.030248552560806274,
-0.03729446232318878,
0.03899860382080078,
0.007440396584570408,
-0.013036186806857586,
0.03458591178059578,
0.006181151140481234,
0.0014223537873476744,
-0.06748512387275696,
0.0004910560674034059,
-0.06662481278181076,
0.01658826693892479,
0.0018258282216265798,
0.010440734215080738,
0.02958672307431698,
-0.07853325456380844,
0.02350207045674324,
-0.03150030970573425,
-0.050685517489910126,
0.046678997576236725,
-0.022616170346736908,
0.05882019177079201,
0.012570424936711788,
-0.018449123948812485,
0.07150593400001526,
-0.10301242023706436,
-0.003140061628073454,
0.14754055440425873,
-0.004494926892220974,
-0.01596885733306408,
-0.015948127955198288,
0.047230739146471024,
-0.06467783451080322,
0.024620017036795616,
0.020453812554478645,
-0.016279367730021477,
0.13289710879325867,
-0.029690148308873177,
0.003914939239621162,
-0.029958250001072884,
0.013731877319514751,
-0.05250219255685806,
-0.10637200623750687,
-0.05619391053915024,
0.050727471709251404,
0.01670469529926777,
-0.02383904904127121,
-0.04482271149754524,
-0.053690701723098755,
0.03323061764240265,
0.0022697290405631065,
0.12933897972106934,
-0.09004959464073181,
0.008392180316150188,
0.01823466829955578,
-0.015169095247983932,
0.00912607554346323,
-0.003211942035704851,
-0.0011760762427002192,
0.012426776811480522,
0.008798503316938877,
-0.03160275146365166,
0.020802482962608337,
-0.0017787880497053266,
0.006345345638692379,
0.04288044944405556,
0.03615393489599228,
0.06296591460704803,
0.010494920425117016,
0.05295039340853691,
-0.04292285814881325,
-0.009724392555654049,
0.03471912816166878,
0.059399597346782684,
0.062306277453899384,
0.00044017532491125166,
-0.023651201277971268,
0.02316688373684883,
0.0008005106938071549,
-0.04705456644296646,
0.08134056627750397,
-0.061853669583797455,
-0.028579045087099075,
-0.07325464487075806,
-0.007601382676512003,
-0.025842711329460144,
0.004222703166306019,
-0.0413304828107357,
-0.009590006433427334,
0.023987600579857826,
-0.04693323001265526,
0.05344107747077942,
0.003272946458309889,
-0.06158578023314476,
0.09136422723531723,
-0.0490620918571949,
0.030646534636616707,
0.07983727753162384,
-0.034749943763017654,
0.021577952429652214,
0.022313322871923447,
0.10593661665916443,
0.10479027777910233,
0.010905088856816292,
0.01398013997823,
0.023780936375260353,
-0.006132334005087614,
-0.050700753927230835,
-0.02226918935775757,
0.007034667767584324,
0.00993749313056469,
-0.021723179146647453,
0.10241279751062393,
-0.07494577765464783,
-7.650696257954723e-34,
-0.03017076849937439,
-0.010815970599651337,
0.010036668740212917,
0.06486430764198303,
-0.0416475385427475,
-0.019300058484077454,
-0.013328482396900654,
-0.028340261429548264,
-0.011994670145213604,
-0.06001437082886696,
0.04605955630540848,
-0.028557967394590378,
0.07831055670976639,
-0.022040171548724174,
-0.06880494952201843,
-0.04163908213376999,
0.06755762547254562,
0.013260617852210999,
0.06312838941812515,
-0.15062229335308075,
-0.04741760715842247,
0.022952796891331673,
-0.004177923779934645,
-0.0690859779715538,
0.004810854326933622,
0.007021237630397081,
0.020570743829011917,
-0.012068785727024078,
0.12084395438432693,
-0.0027447007596492767,
-0.021993353962898254,
-0.08134893327951431,
-0.04301127418875694,
0.019987503066658974,
-0.0020269628148525953,
0.00020206243789289147,
-0.0025390947703272104,
-0.059494808316230774,
0.06426563113927841,
-0.061366818845272064,
-0.11586348712444305,
-0.05487819015979767,
-0.015800846740603447,
-0.04968728497624397,
0.0064959595911204815,
-0.12306270003318787,
-0.09511694312095642,
0.05053948238492012,
-0.04980643466114998,
-0.04929566755890846,
0.06065909191966057,
-0.013031508773565292,
0.013974791392683983,
-0.013228577561676502,
-0.019835691899061203,
0.026676790788769722,
-0.05418035760521889,
0.03260648623108864,
0.07181074470281601,
0.03211928531527519,
0.02923193760216236,
0.0009035893017426133,
-0.07358361035585403,
0.05256490781903267,
0.0013186875730752945,
0.026131724938750267,
-0.05913371220231056,
0.0010765555780380964,
-0.011118724942207336,
0.08478167653083801,
0.006047502625733614,
-0.015474939718842506,
0.1416502743959427,
0.035271644592285156,
-0.0744846761226654,
0.013965384103357792,
0.07045292854309082,
-0.01842997595667839,
-0.030201135203242302,
0.09289633482694626,
-0.02562548965215683,
0.03669621795415878,
-0.09991446137428284,
0.026061510667204857,
-0.045204486697912216,
-0.021980872377753258,
0.016119636595249176,
-0.07752349227666855,
0.05712699517607689,
0.004518995527178049,
0.13383705914020538,
0.08780601620674133,
-0.08076179772615433,
0.09072070568799973,
-0.028625421226024628,
-7.341604610180811e-34,
0.04550124704837799,
-0.04096432030200958,
0.07645010948181152,
-0.045956701040267944,
-0.02902263030409813,
-0.04695163667201996,
0.01799829676747322,
-0.06317625194787979,
0.01818581484258175,
0.026833904907107353,
0.046025972813367844,
-0.015315868891775608,
-0.02918330952525139,
-0.0619761124253273,
0.017344539985060692,
-0.051285117864608765,
0.03157326579093933,
0.0031623959075659513,
0.03563842922449112,
-0.038860585540533066,
-0.022361362352967262,
0.06413983553647995,
-0.04363487288355827,
0.11372766643762589,
-0.12654827535152435,
-0.02848411165177822,
0.00918519590049982,
0.0439833402633667,
0.06355376541614532,
0.06499502807855606,
-0.044515691697597504,
0.029294760897755623,
-0.02227908931672573,
0.006394727621227503,
0.028983401134610176,
0.06754013150930405,
0.03320476785302162,
-0.0306111928075552,
0.003585334401577711,
0.08474305272102356,
-0.05461005121469498,
-0.0046006725169718266,
-0.0039054513908922672,
0.019928647205233574,
0.010380644351243973,
0.07267074286937714,
0.12592081725597382,
0.026017095893621445,
0.026927076280117035,
-0.11200649291276932,
-0.04529654234647751,
-0.010812819935381413,
-0.053846653550863266,
-0.03044213354587555,
-0.013668707571923733,
0.04804416373372078,
0.016930226236581802,
0.00643186317756772,
-0.04729484021663666,
0.021703368052840233,
0.04726073890924454,
-0.060425810515880585,
0.03312220051884651,
-0.04747629910707474,
0.052430760115385056,
0.0842948704957962,
0.014688639901578426,
-0.05162522569298744,
-0.006815378088504076,
0.0822833925485611,
0.11301840096712112,
0.0563696026802063,
-0.058995749801397324,
-0.03386414051055908,
0.039328642189502716,
0.001621104427613318,
-0.046987663954496384,
0.006110554561018944,
-0.03431878983974457,
-0.08791357278823853,
-0.015722688287496567,
0.03765347599983215,
0.008142100647091866,
-0.043633509427309036,
0.03933795541524887,
0.0341300405561924,
-0.02680010348558426,
0.06984035670757294,
-0.07868365198373795,
0.027518171817064285,
0.004650910850614309,
-0.12342382967472076,
-0.07787264138460159,
0.08917499333620071,
-0.04717697948217392,
-2.8309017352512456e-8,
-0.08153409510850906,
0.04779086634516716,
0.0620558075606823,
-0.12256714701652527,
-0.046582967042922974,
0.009483982808887959,
-0.01207968220114708,
-0.011696112342178822,
0.10108790546655655,
0.03383464738726616,
-0.06306614726781845,
0.017909064888954163,
-0.037573330104351044,
-0.05999968573451042,
0.012258652597665787,
0.07021994888782501,
-0.002862564055249095,
0.01156620867550373,
-0.017655929550528526,
-0.10899671912193298,
0.024981394410133362,
-0.020783159881830215,
0.012224161997437477,
-0.03052276000380516,
-0.07503913342952728,
-0.010461129248142242,
-0.04658045619726181,
0.08683139085769653,
0.012777519412338734,
-0.0372534915804863,
-0.04149280861020088,
0.006745439954102039,
0.06626249104738235,
-0.03152920678257942,
0.03410723805427551,
0.03479786962270737,
0.05120168626308441,
0.024033701047301292,
-0.025314800441265106,
0.022406689822673798,
0.042829129844903946,
-0.01698850281536579,
0.001075132517144084,
0.011354717426002026,
-0.056284498423337936,
0.08417372405529022,
0.04020332172513008,
0.04128905013203621,
-0.10007309913635254,
-0.05328311771154404,
0.015227751806378365,
-0.023681389167904854,
-0.05416065454483032,
-0.03753776475787163,
-0.050777606666088104,
0.06077982485294342,
-0.05988897755742073,
-0.007206776645034552,
0.0029323245398700237,
0.01548395399004221,
-0.02391560934484005,
0.034284647554159164,
0.07527236640453339,
-0.044977474957704544
] |
PMID:9548812 | MT1-MMP can also digest extracellular matrix (ECM) such as interstitial collagens, gelatin, and proteoglycan and thus may play an important role in pathophysiological digestion of ECM. | [
-0.02003481425344944,
-0.06251250207424164,
0.04396554455161095,
0.02250143326818943,
0.02325700968503952,
-0.06830223649740219,
-0.02357035130262375,
0.04795556515455246,
-0.030032344162464142,
-0.014872961677610874,
0.011363519355654716,
0.049680814146995544,
0.02178761176764965,
0.02217361144721508,
-0.07529010623693466,
-0.00007160770474001765,
0.011320787481963634,
0.03322438895702362,
0.06492581963539124,
0.044637106359004974,
0.027935145422816277,
-0.0060493662022054195,
-0.016805453225970268,
-0.05774885416030884,
-0.007329968735575676,
-0.03911856934428215,
0.04492912068963051,
0.07096855342388153,
-0.018984278663992882,
-0.07275180518627167,
0.030550014227628708,
0.0028091950807720423,
0.03668248653411865,
-0.015650063753128052,
0.006968142930418253,
0.053154002875089645,
-0.00032877226476557553,
0.00525137921795249,
-0.0813061073422432,
0.0061182305216789246,
0.13175491988658905,
0.01445506140589714,
0.04460304602980614,
-0.08963948488235474,
0.03328237682580948,
-0.11604710668325424,
-0.028202172368764877,
-0.023817844688892365,
-0.02527429908514023,
0.07781049609184265,
-0.04878762364387512,
-0.01121105719357729,
-0.04541974142193794,
0.023368708789348602,
-0.02991369739174843,
-0.0899563580751419,
-0.12201210856437683,
0.011249587871134281,
-0.012073793448507786,
-0.06584905833005905,
-0.059118255972862244,
-0.05489711835980415,
0.03523409366607666,
0.005265262443572283,
0.14129124581813812,
-0.07463553547859192,
0.01872105523943901,
0.03617890924215317,
-0.027149388566613197,
0.07091366499662399,
-0.0544038787484169,
-0.07132935523986816,
-0.0025725695304572582,
0.04041419178247452,
-0.021069083362817764,
0.05998293682932854,
-0.06460616737604141,
-0.03415612131357193,
0.007625469006597996,
0.09981662780046463,
0.02298586256802082,
0.0648457482457161,
0.0348951630294323,
-0.02821035496890545,
0.003907626960426569,
0.05434262752532959,
0.054538749158382416,
0.09179772436618805,
-0.07634066790342331,
-0.04690060019493103,
-0.00511810090392828,
-0.06691417098045349,
-0.015853527933359146,
0.08002817630767822,
-0.0058070882223546505,
-0.06179049238562584,
-0.03351316601037979,
0.06067769601941109,
0.01596502773463726,
-0.0462590754032135,
-0.04904324933886528,
0.10254513472318649,
-0.017969388514757156,
0.010900950990617275,
0.024059105664491653,
0.00808028969913721,
-0.008839908055961132,
0.10648578405380249,
0.054218363016843796,
0.0021306511480361223,
0.07696481049060822,
-0.005951242055743933,
-0.02553124912083149,
0.005570659879595041,
0.06709892302751541,
0.08913126587867737,
0.06040571630001068,
-0.04338840767741203,
0.02991342730820179,
0.04424286633729935,
-0.0704755038022995,
-0.08823734521865845,
0.024556586518883705,
-0.06348298490047455,
-0.017453046515583992,
0.04208013787865639,
-0.02116062492132187,
2.6224467141059198e-33,
-0.050039466470479965,
-0.04215221852064133,
0.0363982729613781,
0.015292606316506863,
0.010199346579611301,
-0.011542970314621925,
-0.02805432118475437,
-0.012937752529978752,
0.02194640412926674,
-0.07307925075292587,
-0.04612855613231659,
0.029320353642106056,
0.07336392998695374,
0.030084114521741867,
-0.12018182873725891,
-0.020462751388549805,
-0.07443075627088547,
-0.03663938492536545,
0.08069732040166855,
-0.0938711166381836,
-0.018527328968048096,
-0.034070923924446106,
0.03294409438967705,
-0.05583503842353821,
0.03166121244430542,
-0.0034886309877038,
-0.002070480491966009,
-0.005663472227752209,
0.04606764018535614,
-0.009560734033584595,
-0.01569610834121704,
-0.0619826503098011,
-0.07567475736141205,
0.025002485141158104,
-0.020789746195077896,
0.06745979189872742,
-0.0344470851123333,
-0.03207525238394737,
0.0308410432189703,
-0.01691310480237007,
-0.027584772557020187,
-0.043216802179813385,
0.01677166298031807,
-0.019276848062872887,
-0.05914059653878212,
-0.09474184364080429,
-0.08288338780403137,
0.04286114498972893,
-0.010815990157425404,
-0.03484578803181648,
0.12714962661266327,
-0.008445654064416885,
0.04265260696411133,
-0.07368651032447815,
-0.04730558395385742,
0.01777583733201027,
-0.05098261684179306,
-0.04020559415221214,
-0.018436146900057793,
0.043369464576244354,
0.004343710839748383,
-0.02807624451816082,
0.03457975015044212,
0.0781497210264206,
0.00006063402906875126,
0.05502183362841606,
-0.10400304198265076,
-0.0047881812788546085,
0.0025226036086678505,
0.04077628627419472,
-0.030424941331148148,
-0.08788290619850159,
0.1181151270866394,
-0.013854892924427986,
0.016160229220986366,
-0.0012085832422599196,
0.05195597931742668,
0.0571090392768383,
-0.06129555404186249,
0.10440821945667267,
0.002208404941484332,
-0.051561981439590454,
-0.05037688463926315,
0.014582687988877296,
-0.05274977907538414,
0.024060314521193504,
0.038736212998628616,
-0.1017458438873291,
0.10636061429977417,
0.048696018755435944,
0.08321501314640045,
0.05779702588915825,
-0.06985680013895035,
0.09228406846523285,
-0.056909456849098206,
-3.224793529354276e-33,
0.08040136098861694,
-0.046386923640966415,
0.04799354076385498,
0.018739603459835052,
-0.03843003138899803,
-0.022027458995580673,
0.05845707654953003,
0.018378905951976776,
0.007535890676081181,
0.03373011201620102,
0.11041303724050522,
0.00632061343640089,
-0.017736976966261864,
-0.05237441137433052,
0.06338828057050705,
0.015026876702904701,
-0.003934148233383894,
-0.01349671371281147,
0.01142555009573698,
-0.038188643753528595,
-0.01853293925523758,
0.08581168949604034,
-0.0007090491708368063,
0.028604326769709587,
-0.012924873270094395,
0.10023142397403717,
-0.018981432542204857,
-0.06238460913300514,
0.015473227947950363,
0.03365409001708031,
-0.04057012498378754,
0.06316559761762619,
-0.03287374600768089,
-0.016849130392074585,
0.011029261164367199,
0.05966904014348984,
-0.03941421955823898,
0.010136840865015984,
0.005966870114207268,
0.03313625603914261,
-0.026399243623018265,
0.05237453803420067,
-0.02932046353816986,
0.039172396063804626,
0.017764287069439888,
-0.009617529809474945,
0.10837110877037048,
0.036303769797086716,
-0.013871485367417336,
-0.02504410408437252,
-0.04151579737663269,
0.04604437202215195,
-0.025319799780845642,
0.01575157418847084,
0.02890060655772686,
0.10505280643701553,
0.009994445368647575,
0.023147890344262123,
-0.00681200111284852,
-0.003941946197301149,
-0.03499983623623848,
-0.012782531790435314,
0.014361705631017685,
-0.07996118813753128,
0.08252701908349991,
0.060953397303819656,
-0.011492311954498291,
-0.039193570613861084,
-0.07313798367977142,
0.09824839234352112,
0.07898049056529999,
0.022107059136033058,
0.0012357892701402307,
0.01295729260891676,
0.06028144061565399,
0.07246630638837814,
-0.09632810950279236,
-0.02692067250609398,
-0.07963957637548447,
-0.09922902286052704,
-0.06485151499509811,
0.013066446408629417,
-0.03444463387131691,
-0.02639208920300007,
0.04308083653450012,
-0.015187380835413933,
-0.039930764585733414,
0.01773565448820591,
-0.06742759048938751,
-0.032903388142585754,
0.02878689393401146,
-0.08556368201971054,
-0.039366960525512695,
0.009125831536948681,
0.014005142264068127,
-3.0632545389153165e-8,
-0.03089192882180214,
-0.0518190972507,
-0.03656955435872078,
-0.04475795477628708,
-0.014980288222432137,
-0.0532200001180172,
-0.05771550163626671,
0.043208204209804535,
0.11819519102573395,
0.06459815800189972,
0.02023225463926792,
0.04055497422814369,
-0.019878873601555824,
-0.055854614824056625,
0.02937469072639942,
0.01032042596489191,
-0.048835352063179016,
-0.013653753325343132,
-0.048136286437511444,
-0.07619091868400574,
-0.05830560624599457,
-0.033393245190382004,
-0.010822470299899578,
0.08805681765079498,
0.04167412966489792,
-0.006584948860108852,
0.0037111889105290174,
0.1321917325258255,
0.016443563625216484,
-0.06878442317247391,
-0.02340460568666458,
0.02346799708902836,
0.027588631957769394,
0.034888774156570435,
-0.0031795131508260965,
0.06180619075894356,
0.06874702870845795,
0.017229584977030754,
-0.06981749087572098,
-0.0024245050735771656,
-0.009982150048017502,
-0.10486235469579697,
0.03692692890763283,
-0.012192806228995323,
-0.07702112942934036,
0.02576359547674656,
-0.007798325270414352,
0.07594258338212967,
-0.04467577487230301,
-0.061476223170757294,
-0.04326712712645531,
-0.01920549012720585,
-0.0022734280209988356,
-0.026794126257300377,
-0.028682779520750046,
0.004399885423481464,
-0.008404800668358803,
0.01447876077145338,
0.08326190710067749,
0.01444656029343605,
-0.004819865338504314,
0.026623660698533058,
0.10240329056978226,
-0.08289577811956406
] |
PMID:9548812 | We studied the inhibitory effect of various hydroxamate MMP inhibitors, including known inhibitors such as BB-94, BB-2516, GM6001, and Ro31-9790, on a deletion mutant of MT1-MMP lacking the transmembrane domain (DeltaMT1) to further characterize the enzyme and develop a selective inhibitor for MT1-MMP. | [
-0.06078719347715378,
-0.095488041639328,
0.029528671875596046,
0.0024098290596157312,
0.008013791404664516,
-0.02601502649486065,
-0.055122312158346176,
0.06050734221935272,
-0.013064468279480934,
-0.04507487639784813,
-0.03257043659687042,
-0.0054647065699100494,
0.029475323855876923,
0.02902546338737011,
-0.02585914544761181,
0.08615692704916,
0.015096313320100307,
0.04914961755275726,
0.07054269313812256,
0.0682302713394165,
-0.004211036022752523,
-0.021365799009799957,
-0.014869410544633865,
-0.010103602893650532,
0.0095834881067276,
0.074378103017807,
0.056044626981019974,
0.04503902047872543,
-0.007346506230533123,
-0.06242905557155609,
0.0170596931129694,
0.058451276272535324,
0.0418533980846405,
-0.06906194984912872,
0.031126834452152252,
0.05731964856386185,
-0.05257880687713623,
-0.0020556824747473,
-0.08621177077293396,
-0.06019359081983566,
0.10189888626337051,
-0.05385061725974083,
0.0641627237200737,
-0.0951300635933876,
0.023841898888349533,
-0.11716962605714798,
-0.054963842034339905,
0.03694489970803261,
-0.031197892501950264,
0.11978361755609512,
-0.007454191334545612,
-0.06249616667628288,
-0.07143572717905045,
0.06712324917316437,
-0.015685109421610832,
-0.09189976751804352,
-0.06711531430482864,
0.10501733422279358,
0.02817363850772381,
0.02405872754752636,
-0.001037831068970263,
0.052343953400850296,
0.02810753881931305,
0.010947360657155514,
0.09353355318307877,
-0.022656532004475594,
-0.007248885929584503,
-0.026391681283712387,
0.034248270094394684,
0.005198574624955654,
-0.05936383455991745,
-0.07124879211187363,
-0.011265436187386513,
-0.00200678501278162,
-0.02573425881564617,
0.016248971223831177,
-0.011927313171327114,
0.019922861829400063,
0.047738783061504364,
0.034542664885520935,
-0.0000028719944111799123,
-0.028270578011870384,
0.0811932161450386,
0.03587837889790535,
0.009306186810135841,
0.0503971204161644,
0.011794543825089931,
0.0487947016954422,
0.03822536766529083,
-0.01662200503051281,
0.00992613285779953,
0.027436668053269386,
-0.0504886768758297,
0.05395165830850601,
-0.027708491310477257,
0.004593595862388611,
-0.07973157614469528,
0.06000813841819763,
-0.05410612374544144,
-0.02256939746439457,
0.024013424292206764,
0.07459979504346848,
-0.04560922831296921,
0.007992483675479889,
0.04885683208703995,
-0.03641221299767494,
0.037978626787662506,
0.06466919183731079,
-0.043793827295303345,
-0.07287675887346268,
-0.002239191671833396,
-0.00286104972474277,
0.03655274957418442,
0.019816435873508453,
0.0691986158490181,
-0.004996966104954481,
0.030689124017953873,
-0.043436527252197266,
0.0026135758962482214,
0.01669556088745594,
-0.027382103726267815,
-0.0674695149064064,
-0.03889204561710358,
-0.027093347162008286,
0.00767436483874917,
0.10236937552690506,
-0.04206393286585808,
1.0733023820915673e-33,
0.0024312331806868315,
-0.033472295850515366,
0.04697376489639282,
0.02257254533469677,
0.014137458056211472,
-0.03844084590673447,
-0.016734447330236435,
-0.03277427330613136,
-0.07660941779613495,
-0.02409321255981922,
-0.04663877934217453,
-0.04443449154496193,
0.04819083958864212,
0.038461148738861084,
-0.014776808209717274,
-0.03642536699771881,
0.10447055101394653,
-0.04885183647274971,
0.10900159180164337,
-0.09178142994642258,
0.012967403046786785,
0.04464591667056084,
-0.016160978004336357,
0.006007752846926451,
-0.028375590220093727,
0.053037259727716446,
-0.03103189915418625,
0.02500610053539276,
0.04346470907330513,
-0.01046947855502367,
-0.08051521331071854,
-0.04384195804595947,
-0.12172017991542816,
0.02228907123208046,
-0.053523678332567215,
0.022587090730667114,
-0.034429725259542465,
-0.10777004808187485,
-0.003694774815812707,
-0.02075839228928089,
-0.060331083834171295,
-0.023305563256144524,
-0.0643189549446106,
-0.07601985335350037,
0.0340288020670414,
-0.03650437667965889,
-0.04205562546849251,
0.011938623152673244,
-0.025693729519844055,
0.013033571653068066,
0.06525421142578125,
0.0060861483216285706,
0.0065946695394814014,
0.036689430475234985,
-0.031133314594626427,
0.00903098750859499,
-0.07894711196422577,
0.04723956063389778,
0.0011952281929552555,
0.03355182334780693,
0.016885291785001755,
0.005711745470762253,
-0.03616316244006157,
0.08347014337778091,
0.06650716811418533,
0.00805195327848196,
0.04580710083246231,
-0.06042573228478432,
-0.02876129560172558,
0.033140022307634354,
-0.04578208550810814,
-0.03413938358426094,
0.10682134330272675,
0.06957222521305084,
0.04343119636178017,
-0.019987260922789574,
0.06071428209543228,
0.02834918722510338,
0.05870380252599716,
0.06130358576774597,
0.061703287065029144,
-0.014391537755727768,
0.012171216309070587,
-0.005050108768045902,
-0.05429717153310776,
-0.05577346310019493,
0.021196141839027405,
-0.0922020673751831,
0.0000659805373288691,
0.011249251663684845,
0.10552166402339935,
-0.015660081058740616,
-0.05998630076646805,
0.10727350413799286,
-0.005783772096037865,
-2.6718591701557116e-33,
0.07793411612510681,
-0.04143422842025757,
0.07885526120662689,
-0.05991746857762337,
-0.1151546835899353,
-0.004864927846938372,
0.048334069550037384,
-0.07121558487415314,
0.1029433161020279,
-0.0413060188293457,
0.1345556527376175,
-0.015506455674767494,
-0.00419284962117672,
-0.12125195562839508,
-0.005233946722000837,
-0.05678549408912659,
0.05813055485486984,
-0.04661479592323303,
-0.004920528270304203,
-0.027444198727607727,
-0.0005492005730047822,
0.07734719663858414,
-0.03449359908699989,
0.09613608568906784,
-0.07111907005310059,
0.02284688875079155,
0.02338583581149578,
-0.007980041205883026,
-0.0010008069220930338,
0.08347563445568085,
-0.011650723405182362,
0.10002146661281586,
-0.06017298996448517,
-0.05413282290101051,
0.0029453281313180923,
0.004832512699067593,
-0.05568351596593857,
0.03817915916442871,
0.023993544280529022,
-0.011246803216636181,
0.027092326432466507,
0.027965225279331207,
-0.051629070192575455,
-0.05401650816202164,
0.049196165055036545,
0.02962886542081833,
-0.0050850315019488335,
-0.02576826885342598,
0.021894587203860283,
-0.08208179473876953,
-0.06460091471672058,
0.03820823132991791,
-0.003938554786145687,
-0.026335950940847397,
0.036242853850126266,
0.01032300665974617,
0.04161757975816727,
-0.010468637570738792,
0.08698377758264542,
-0.014298970811069012,
-0.026322955265641212,
0.023696737363934517,
0.01906653866171837,
0.006356061901897192,
0.009881390258669853,
0.17468899488449097,
0.057232145220041275,
0.008824183605611324,
0.03356541320681572,
0.004786098375916481,
0.02065926417708397,
0.06041516363620758,
0.003419669112190604,
0.048625215888023376,
-0.0029518676456063986,
0.045647695660591125,
-0.04018976911902428,
-0.019544733688235283,
-0.06704127788543701,
-0.10783006995916367,
0.07912929356098175,
0.034390855580568314,
-0.03493288904428482,
-0.08328008651733398,
-0.023677950724959373,
-0.013461243361234665,
-0.02544056996703148,
0.04282192513346672,
0.03279656544327736,
-0.0420595221221447,
0.02074313536286354,
-0.11364699900150299,
-0.07192873954772949,
0.0030184690840542316,
0.010896047577261925,
-3.938032477890374e-8,
-0.01768706925213337,
-0.015266051515936852,
0.0019743151497095823,
-0.07757285237312317,
-0.048216670751571655,
0.08407790213823318,
-0.03793411701917648,
0.02776981145143509,
0.06558933854103088,
0.06399590522050858,
-0.018502408638596535,
0.02788505330681801,
-0.028154801577329636,
-0.016254408285021782,
0.011886462569236755,
0.001232147216796875,
-0.0201727282255888,
-0.011777729727327824,
-0.017289239913225174,
-0.05680679529905319,
-0.023673787713050842,
0.005978992208838463,
-0.00448321457952261,
0.035507019609212875,
0.08013192564249039,
-0.07762213051319122,
-0.026987947523593903,
0.056919436901807785,
0.07769963890314102,
-0.019310537725687027,
0.017346329987049103,
0.02550596557557583,
0.053531959652900696,
0.03379620984196663,
0.0049922047182917595,
0.017580779269337654,
0.03168661519885063,
0.009115798398852348,
-0.03331678360700607,
0.07630862295627594,
0.032644834369421005,
-0.03248462453484535,
-0.019498001784086227,
-0.07289561629295349,
-0.05330084264278412,
0.044668763875961304,
0.058761294931173325,
0.011458837427198887,
-0.07464084774255753,
-0.05203839763998985,
0.034387584775686264,
0.03622637316584587,
-0.08735093474388123,
-0.08847604691982269,
-0.04497933387756348,
0.024616478011012077,
0.0018854797817766666,
-0.026823611930012703,
-0.02620518207550049,
-0.1303597390651703,
-0.05830135941505432,
-0.1271798014640808,
0.05030105635523796,
-0.08984004706144333
] |
PMID:9548812 | The evaluation of the inhibitory activities of various hydroxamates reveals general structural profiles affecting selectivities toward MMPs. | [
-0.026543302461504936,
-0.09539362043142319,
0.048159487545490265,
0.01922185719013214,
0.007276224438101053,
0.03768701106309891,
-0.039737518876791,
0.04054959490895271,
0.01590251736342907,
-0.01958428882062435,
-0.014371245168149471,
-0.02138928323984146,
-0.010712157003581524,
0.048286281526088715,
-0.039051637053489685,
0.06629188358783722,
0.04932756349444389,
0.041519954800605774,
0.05297401547431946,
0.08480866253376007,
-0.02041567489504814,
-0.08587494492530823,
-0.02531062811613083,
-0.00003314607238280587,
-0.014667232520878315,
0.1442396342754364,
0.020681990310549736,
0.07173961400985718,
-0.0074980896897614,
-0.10004342347383499,
0.011440909467637539,
0.07125204801559448,
0.11273102462291718,
-0.13479621708393097,
0.03169256076216698,
0.023468736559152603,
-0.04235561564564705,
-0.04362080246210098,
-0.049586400389671326,
-0.04330431669950485,
0.07876503467559814,
-0.05290945619344711,
0.014064892195165157,
-0.08030254393815994,
0.04272718355059624,
-0.10282249748706818,
-0.029923316091299057,
-0.013788675889372826,
-0.06411927938461304,
0.11298032104969025,
-0.0003189444832969457,
-0.0834307074546814,
-0.011521371081471443,
0.06911014020442963,
-0.03464025631546974,
-0.019995970651507378,
-0.0806296244263649,
0.08959218114614487,
0.040759533643722534,
-0.009790231473743916,
0.010947098955512047,
0.04763936996459961,
-0.0008517469395883381,
0.03697379305958748,
0.056440867483615875,
0.03931315243244171,
-0.024515768513083458,
-0.04115642234683037,
-0.006597267463803291,
-0.020637625828385353,
-0.08605939149856567,
-0.05049547553062439,
0.058312512934207916,
0.015961341559886932,
-0.003923955839127302,
0.03363313525915146,
0.007705177646130323,
-0.022061539813876152,
0.07558778673410416,
0.0403653085231781,
-0.04438403993844986,
0.016488926485180855,
0.08317935466766357,
0.06249057129025459,
0.057023920118808746,
0.04432113841176033,
0.05469803512096405,
0.04318320378661156,
0.026131728664040565,
-0.034212060272693634,
-0.061433855444192886,
0.032350774854421616,
-0.03672073408961296,
0.05732137709856033,
0.07373320311307907,
0.09285896271467209,
-0.07799191027879715,
0.05626541003584862,
0.005102234426885843,
-0.043687187135219574,
0.03793184086680412,
0.030558111146092415,
-0.06481464952230453,
-0.012645500712096691,
0.011955143883824348,
-0.03450436890125275,
0.017694009467959404,
0.06816933304071426,
0.009997732937335968,
-0.041382450610399246,
-0.03985404968261719,
-0.00927011203020811,
0.021975800395011902,
0.0085546700283885,
-0.01126191858202219,
-0.0037654689513146877,
0.05580038204789162,
-0.04611435532569885,
0.006328445393592119,
-0.08097852021455765,
-0.012700547464191914,
-0.07174647599458694,
0.018175888806581497,
-0.02993324026465416,
0.02967890352010727,
0.09934572130441666,
-0.008149405010044575,
-2.3014467575452004e-33,
0.0021345324348658323,
-0.032240428030490875,
0.053432051092386246,
-0.03620500490069389,
-0.025604525581002235,
-0.058396223932504654,
-0.01025485247373581,
-0.03530590608716011,
-0.04074987769126892,
-0.009334779344499111,
-0.09557730704545975,
0.016553450375795364,
-0.008652622811496258,
0.0461832731962204,
-0.0016321992734447122,
-0.05778718367218971,
0.06367214769124985,
-0.00924949161708355,
0.08449243009090424,
-0.07641521841287613,
0.010067063383758068,
0.0378650464117527,
-0.07311148196458817,
-0.010079901665449142,
-0.02227494865655899,
0.023394133895635605,
-0.0516299232840538,
-0.029674923047423363,
-0.009299568831920624,
-0.01803286001086235,
-0.02668476291000843,
-0.01804681308567524,
-0.08227317035198212,
0.049602754414081573,
-0.03458219766616821,
0.06020782142877579,
-0.08846410363912582,
-0.08414404094219208,
0.01038807351142168,
-0.012804140336811543,
0.0021284082904458046,
0.03577973321080208,
-0.01308008935302496,
-0.049758054316043854,
0.000339222839102149,
-0.01559610664844513,
-0.06690863519906998,
-0.06188465654850006,
-0.01948647014796734,
-0.017930245026946068,
0.06999494135379791,
0.055907826870679855,
0.01004005130380392,
0.05373724550008774,
-0.07374410331249237,
0.06372753530740738,
-0.06300663948059082,
0.03315391391515732,
-0.01000179536640644,
0.07576540112495422,
-0.09563495963811874,
-0.0037855573464185,
-0.057989366352558136,
0.0242904145270586,
0.04101043567061424,
0.04655639827251434,
-0.006868262775242329,
0.009581312537193298,
-0.020000742748379707,
0.03186740353703499,
-0.01053368579596281,
-0.03306717053055763,
0.11998632550239563,
0.047305960208177567,
0.03331657126545906,
-0.026090271770954132,
0.03336051106452942,
0.05901235714554787,
0.04558698087930679,
0.1100965365767479,
0.05301838740706444,
-0.02462778054177761,
-0.058724191039800644,
-0.0017125618178397417,
-0.10091794282197952,
-0.012943941168487072,
0.01795816980302334,
-0.03328600153326988,
0.04695477336645126,
0.03929930925369263,
0.10467130690813065,
-0.06365072727203369,
-0.0871705636382103,
0.059767697006464005,
0.004565270617604256,
-5.245755579849771e-34,
0.09379559010267258,
-0.04734816029667854,
0.05843872204422951,
-0.014143561944365501,
-0.04730943590402603,
0.010008232668042183,
0.03334944695234299,
-0.10678061097860336,
0.1157420426607132,
-0.021489471197128296,
0.12344451248645782,
0.05925469845533371,
-0.022776542231440544,
-0.082000732421875,
-0.05817224085330963,
0.042180124670267105,
0.02887663058936596,
-0.02253725193440914,
0.03639565035700798,
-0.09962563216686249,
0.02475680410861969,
-0.002371852518990636,
-0.007425164803862572,
0.0528564527630806,
0.031171264126896858,
0.026938673108816147,
0.018339239060878754,
-0.06436001509428024,
0.024272365495562553,
0.06151299923658371,
-0.014712976291775703,
0.0653679370880127,
-0.0486011803150177,
-0.040756698697805405,
0.06336283683776855,
-0.004558198619633913,
-0.10166062414646149,
0.033023085445165634,
-0.001875950489193201,
-0.0281636044383049,
-0.04368225857615471,
-0.02179841510951519,
-0.014220074750483036,
0.006799307186156511,
0.05880722030997276,
0.0880608931183815,
0.0391751267015934,
-0.0704963430762291,
0.01956033520400524,
0.017314651980996132,
-0.03939266875386238,
0.0483681820333004,
-0.0788944810628891,
-0.003583283629268408,
0.018215350806713104,
0.01651100255548954,
0.021004734560847282,
-0.03984617069363594,
-0.0019169283332303166,
-0.02778434380888939,
-0.008638165891170502,
0.08604834973812103,
0.02486291714012623,
-0.029794270172715187,
-0.0609222911298275,
0.1417914628982544,
0.0009599149343557656,
0.02234773337841034,
0.011107980273663998,
-0.0315961018204689,
-0.019076285883784294,
-0.020159132778644562,
0.07991617172956467,
0.025421258062124252,
-0.012288158759474754,
-0.0493403859436512,
-0.01795637607574463,
-0.028516525402665138,
-0.044143736362457275,
-0.07358971238136292,
0.07850846648216248,
0.05889014154672623,
-0.04359940066933632,
-0.06127496808767319,
-0.0396292582154274,
0.017725849524140358,
0.0015424854354932904,
0.018044471740722656,
0.0175767969340086,
-0.02312481217086315,
0.05259813740849495,
-0.04159178584814072,
-0.02136014960706234,
0.05669368430972099,
0.04095203056931496,
-2.554543776511764e-8,
-0.025916051119565964,
-0.018931185826659203,
-0.0026351455599069595,
-0.08096355199813843,
-0.0403156578540802,
0.10097526758909225,
-0.04557201266288757,
0.0644078329205513,
0.04427315294742584,
-0.005324648693203926,
0.06487584859132767,
-0.007808039430528879,
-0.03514756262302399,
-0.020345916971564293,
0.014365669339895248,
-0.051166415214538574,
-0.024912742897868156,
-0.052431609481573105,
-0.029327021911740303,
-0.07270757108926773,
-0.07673541456460953,
0.026265421882271767,
-0.012222131714224815,
0.05286215618252754,
-0.01596638187766075,
-0.03050732985138893,
0.004325616639107466,
-0.03087039850652218,
0.043602198362350464,
0.017770785838365555,
0.021658621728420258,
0.06659283488988876,
-0.008922101929783821,
0.032560184597969055,
-0.0005199851002544165,
0.06217971444129944,
0.0322333388030529,
-0.004575482103973627,
-0.05613009259104729,
0.059824440628290176,
0.013882880099117756,
-0.06988495588302612,
0.000007223448392323917,
-0.07220660895109177,
-0.02810327149927616,
0.09117164462804794,
-0.08271341770887375,
0.00907137431204319,
-0.0566219761967659,
-0.019520262256264687,
0.04300050437450409,
-0.01671941578388214,
-0.058933015912771225,
-0.0404805913567543,
-0.0406428799033165,
0.028400050476193428,
-0.018603947013616562,
-0.08372309803962708,
-0.02072567492723465,
-0.14317357540130615,
-0.04235594719648361,
-0.11890383064746857,
0.10971824079751968,
-0.01783105917274952
] |
PMID:9548812 | In particular, a longer side chain at the P1' position is preferable for the binding to MMP-2, -3, and -9 and MT1-MMP. | [
-0.11946800351142883,
-0.049552593380212784,
0.028220830485224724,
-0.06302621215581894,
-0.0688026174902916,
0.0013955819886177778,
-0.07028267532587051,
0.11009480059146881,
-0.0019476049346849322,
-0.015903625637292862,
0.08210407942533493,
0.04611329361796379,
-0.02753511629998684,
0.012934128753840923,
-0.006356528960168362,
0.058205850422382355,
-0.003031762083992362,
0.046790096908807755,
0.1560087949037552,
0.06900659948587418,
-0.0057633258402347565,
-0.03748432919383049,
-0.028040215373039246,
-0.011381015181541443,
-0.006905072368681431,
0.02821335382759571,
0.012471498921513557,
0.1108141615986824,
0.06728561967611313,
-0.09333616495132446,
-0.03373049572110176,
0.0078444117680192,
0.0017856914782896638,
-0.04081445932388306,
-0.019311729818582535,
0.06930676102638245,
-0.0069592902436852455,
0.04073883593082428,
-0.04554808884859085,
0.016759289428591728,
0.1228196769952774,
0.00020759210747200996,
0.09909714013338089,
-0.04180542379617691,
-0.07116209715604782,
-0.04346364736557007,
-0.04065735265612602,
0.06062604486942291,
-0.02724708430469036,
0.05565962195396423,
0.043173931539058685,
-0.023999584838747978,
-0.09884011745452881,
0.06954417377710342,
0.02087133564054966,
-0.00009239108476322144,
-0.10646242648363113,
0.0395999513566494,
0.008670308627188206,
-0.05030207708477974,
-0.019979333505034447,
0.07742385566234589,
-0.08782851696014404,
0.000406676932470873,
0.10260835289955139,
-0.006954723037779331,
0.05503300577402115,
-0.037249382585287094,
-0.05692524462938309,
0.12997090816497803,
-0.04914063215255737,
-0.03169628232717514,
-0.07635106146335602,
-0.029584454372525215,
0.027340222150087357,
0.09768995642662048,
-0.024998920038342476,
-0.036469198763370514,
-0.026720188558101654,
-0.012112662196159363,
0.0029147688765078783,
0.04744476452469826,
0.011882644146680832,
0.027086568996310234,
0.03371910750865936,
0.00895115826278925,
-0.04117116704583168,
-0.0005593655514530838,
0.002786232391372323,
-0.07322272658348083,
0.05105539411306381,
-0.03588426485657692,
-0.02198188379406929,
0.050889454782009125,
-0.03120892122387886,
0.024858001619577408,
-0.053159404546022415,
0.1035478413105011,
-0.03068080171942711,
0.006056864280253649,
0.0480174645781517,
0.04681704565882683,
-0.06360223889350891,
0.022793704643845558,
-0.011892409063875675,
-0.023314421996474266,
-0.046319473534822464,
-0.05899982899427414,
-0.03529788553714752,
-0.010904609225690365,
-0.006915980949997902,
0.01576179638504982,
-0.012261385098099709,
-0.08561964333057404,
0.0041108932346105576,
-0.007831663824617863,
-0.0038143093697726727,
0.09061943739652634,
0.046860288828611374,
-0.0005532269133254886,
-0.039417434483766556,
-0.055239275097846985,
-0.09792950004339218,
0.022662166506052017,
-0.004331199452280998,
0.022607479244470596,
-0.04665565490722656,
1.0151954922785138e-33,
0.007062224671244621,
-0.010565982200205326,
0.08905211836099625,
0.0219622403383255,
0.027498554438352585,
0.014194376766681671,
-0.020901428535580635,
-0.09030043333768845,
-0.127515971660614,
0.021511279046535492,
-0.020588336512446404,
-0.052356380969285965,
0.024275295436382294,
-0.003750158241018653,
-0.01650284230709076,
-0.07371662557125092,
0.025346029549837112,
0.025881433859467506,
0.0013592798495665193,
-0.04263170808553696,
0.01830950938165188,
-0.01747099868953228,
-0.01772906258702278,
-0.01943305879831314,
0.07335085421800613,
0.05404859781265259,
0.04631071537733078,
0.059885408729314804,
-0.02927057072520256,
-0.009113886393606663,
-0.02211029827594757,
-0.03403015434741974,
-0.09096008539199829,
-0.0316711962223053,
-0.02264028787612915,
-0.001292955013923347,
-0.003058795351535082,
-0.06669625639915466,
-0.0068910191766917706,
-0.0925111323595047,
-0.025956498458981514,
0.03403010591864586,
-0.023806793615221977,
-0.046114157885313034,
0.005278632510453463,
-0.05412831902503967,
0.0169278122484684,
0.025402802973985672,
-0.027224738150835037,
0.007394230924546719,
0.05427410826086998,
0.011569127440452576,
0.013298502191901207,
0.018476301804184914,
-0.00015077511488925666,
-0.047676991671323776,
-0.029584847390651703,
0.04075779765844345,
-0.03152333199977875,
0.08147065341472626,
0.0370355099439621,
0.018762918189167976,
0.059692736715078354,
0.025629479438066483,
0.011876991018652916,
0.08623908460140228,
-0.09229280054569244,
-0.09917815029621124,
0.08359356969594955,
0.017230097204446793,
-0.0167592391371727,
-0.01544867642223835,
0.09910447895526886,
0.09207433462142944,
0.021906130015850067,
0.03555968403816223,
-0.03206338360905647,
0.02209683321416378,
0.08329351991415024,
-0.011662918142974377,
-0.036399535834789276,
0.02224062755703926,
-0.05979681760072708,
0.06504936516284943,
-0.05862553045153618,
-0.11969737708568573,
0.012611068785190582,
-0.07615743577480316,
0.019947348162531853,
0.0377657487988472,
0.008285227231681347,
0.011628258042037487,
0.060255855321884155,
0.06836996227502823,
-0.037122875452041626,
-1.5824732702800106e-33,
-0.014716332778334618,
-0.04188153147697449,
0.0860915407538414,
0.007162428926676512,
-0.11828939616680145,
0.005540074780583382,
0.11080450564622879,
-0.0727396160364151,
0.0013160363305360079,
0.06574146449565887,
0.11850481480360031,
0.04005584120750427,
-0.11019231379032135,
-0.09349219501018524,
0.07777877897024155,
0.025597337633371353,
-0.014671100303530693,
0.011338083073496819,
0.08482639491558075,
-0.050969213247299194,
0.0901031419634819,
0.05902789905667305,
-0.0644935891032219,
0.11095073819160461,
-0.02843063697218895,
0.0018019829876720905,
0.047980159521102905,
-0.007245718501508236,
-0.019185494631528854,
0.031071839854121208,
-0.09138945490121841,
0.08440802246332169,
-0.008671286515891552,
-0.03651627153158188,
-0.10189282894134521,
0.00455711642280221,
-0.07137008011341095,
0.08631355315446854,
0.04894768446683884,
0.045500028878450394,
0.035645611584186554,
0.056249476969242096,
0.0408005453646183,
0.026637664064764977,
-0.02051256038248539,
-0.008805153891444206,
0.10567574203014374,
0.02326962538063526,
0.04813021048903465,
-0.023321062326431274,
-0.11778570711612701,
0.02744233049452305,
-0.01200941577553749,
-0.043341703712940216,
0.011599868535995483,
0.05060479789972305,
-0.04895886033773422,
0.00644721882417798,
0.060118358582258224,
0.046707458794116974,
-0.04196027293801308,
0.03750156983733177,
0.004029429517686367,
-0.06041745841503143,
0.025854121893644333,
0.07714949548244476,
0.07517942786216736,
-0.062493033707141876,
0.012740548700094223,
-0.023194458335638046,
0.022089842706918716,
0.060025837272405624,
0.09115003794431686,
0.0250944085419178,
0.03367650881409645,
-0.0597815103828907,
0.046979621052742004,
0.03414858132600784,
0.004177112132310867,
-0.008575323037803173,
-0.021526578813791275,
-0.052783336490392685,
-0.09233833104372025,
0.031226392835378647,
-0.016621533781290054,
-0.018160970881581306,
0.028362443670630455,
0.04159024730324745,
0.009510851465165615,
-0.044824499636888504,
0.01834205351769924,
0.025399023666977882,
0.025777088478207588,
0.013574294745922089,
0.024783898144960403,
-3.027633610486191e-8,
0.005382210481911898,
-0.04659559205174446,
0.038815174251794815,
-0.04974459484219551,
-0.09418351948261261,
0.04142586141824722,
-0.009245848283171654,
0.016553685069084167,
0.029929112643003464,
0.04999268054962158,
0.0639103576540947,
0.02210327424108982,
-0.04663300886750221,
-0.01895579881966114,
0.05581308901309967,
0.012823137454688549,
-0.030163558200001717,
-0.05597103759646416,
-0.07310236245393753,
-0.0380953773856163,
-0.06106947362422943,
-0.0010166480205953121,
0.03597719222307205,
-0.003133170073851943,
-0.03256019949913025,
-0.018704362213611603,
-0.027138350531458855,
0.09225098043680191,
0.02286568097770214,
0.018451539799571037,
0.04149201884865761,
0.05696222931146622,
-0.023752301931381226,
0.013928698375821114,
-0.004144311882555485,
-0.03279047831892967,
-0.06429441273212433,
0.05886933207511902,
0.02598581835627556,
0.06529796868562698,
0.004765079356729984,
-0.059188880026340485,
0.01951410062611103,
0.025877023115754128,
-0.015935933217406273,
0.05912955105304718,
-0.006235694047063589,
0.023567700758576393,
-0.0876884013414383,
-0.013573736883699894,
-0.00019392087415326387,
-0.015172068029642105,
0.002630420960485935,
-0.08497993648052216,
-0.02722388319671154,
-0.0165267214179039,
-0.021526915952563286,
-0.007369435392320156,
-0.06519750505685806,
-0.024286018684506416,
-0.059010058641433716,
-0.06456991285085678,
-0.04456716775894165,
-0.02424108050763607
] |
PMID:9548812 | For the P2' position, an alpha-branched alkyl group is critical for the binding toward DeltaMT1, while the introduction of a bulky group at the alpha-position of hydroxamic acid seems to diminish the activity against DeltaMT1. | [
-0.04866526648402214,
-0.10824888199567795,
0.004548365715891123,
-0.022579709067940712,
-0.006706365384161472,
0.025067193433642387,
-0.007777665741741657,
0.04008231312036514,
0.061800163239240646,
-0.019191032275557518,
0.09442997723817825,
0.03026467189192772,
-0.06049029529094696,
-0.022968370467424393,
0.04790768772363663,
0.04527232423424721,
-0.021458184346556664,
-0.010968673974275589,
0.034588731825351715,
-0.0007274471572600305,
0.01781604066491127,
-0.046045850962400436,
0.05253776162862778,
0.00864182785153389,
-0.06538651883602142,
0.08815061300992966,
0.02247980237007141,
0.10345659404993057,
0.12986129522323608,
-0.14691750705242157,
0.055066294968128204,
0.06942852586507797,
0.022378651425242424,
0.004364406690001488,
-0.041654832661151886,
0.04870843142271042,
-0.0722787156701088,
-0.055953238159418106,
-0.01120276004076004,
0.002963720355182886,
0.1431017518043518,
-0.008038711734116077,
0.057534653693437576,
-0.0017777109751477838,
-0.0037071965634822845,
-0.03741650655865669,
0.040071405470371246,
-0.028825340792536736,
-0.010318120941519737,
0.04282033070921898,
0.050190672278404236,
-0.057308442890644073,
0.00437561422586441,
0.020175175741314888,
-0.05855151265859604,
0.05666959285736084,
-0.036128804087638855,
0.1185186356306076,
0.008678194135427475,
-0.010358001105487347,
0.04867806285619736,
0.0863034799695015,
-0.03964162617921829,
0.04032852128148079,
0.01577609032392502,
-0.014041404239833355,
0.06989207118749619,
-0.07937245070934296,
0.0012951348908245564,
0.0377328135073185,
-0.09228330850601196,
0.02315637283027172,
-0.023491613566875458,
0.007182398810982704,
0.005786734167486429,
0.019902942702174187,
-0.020010149106383324,
-0.07834204286336899,
-0.00563431391492486,
-0.051554180681705475,
0.02717909961938858,
-0.04460400342941284,
0.03466390073299408,
0.06494143605232239,
-0.04951022192835808,
0.0034314338117837906,
-0.03519540652632713,
0.021789416670799255,
-0.010528012178838253,
-0.057576872408390045,
0.063959039747715,
0.07441604137420654,
0.010196259245276451,
0.042023640125989914,
-0.007438719272613525,
0.09445880353450775,
0.01768152415752411,
-0.0036943145096302032,
0.018139824271202087,
0.013120206072926521,
0.045379359275102615,
0.1028733104467392,
-0.0944332554936409,
-0.06407547742128372,
-0.03314472734928131,
-0.016455285251140594,
-0.02814660407602787,
-0.06888880580663681,
-0.019029228016734123,
0.027212675660848618,
-0.007921268232166767,
-0.055296141654253006,
0.02082683891057968,
0.02611054666340351,
-0.04170012101531029,
-0.01782912015914917,
0.06996063888072968,
0.028468841686844826,
-0.01600794494152069,
-0.07390832901000977,
-0.02757120691239834,
-0.08316247910261154,
-0.023337390273809433,
0.0029827875550836325,
-0.06147191300988197,
0.03614607825875282,
-0.10664019733667374,
-2.8942435880686505e-35,
0.078617163002491,
0.01064571924507618,
0.01637110859155655,
0.027970336377620697,
-0.011274601332843304,
-0.05236532539129257,
-0.022424161434173584,
-0.12757137417793274,
-0.12050902098417282,
0.007934417575597763,
-0.021118013188242912,
-0.023163069039583206,
0.015666617080569267,
0.05689893290400505,
-0.0036688544787466526,
-0.047220274806022644,
-0.00872881431132555,
-0.013347967527806759,
0.016516467556357384,
-0.02154167927801609,
0.012770415283739567,
0.09140694886445999,
-0.047443535178899765,
-0.0693918913602829,
0.032358162105083466,
0.06495706737041473,
-0.006667746230959892,
0.024155275896191597,
-0.0539851114153862,
0.003830232657492161,
-0.05980726331472397,
0.001384994713589549,
-0.15632353723049164,
0.038265276700258255,
0.02328578196465969,
0.006288144737482071,
-0.050250906497240067,
-0.027098508551716805,
0.04257170483469963,
-0.07943586260080338,
0.002334499964490533,
0.01643112488090992,
0.015952525660395622,
-0.01627839170396328,
0.050619274377822876,
-0.02232416532933712,
-0.034045588225126266,
0.049789171665906906,
0.02917688712477684,
-0.007674254942685366,
0.003226424101740122,
-0.003945379052311182,
0.0010737847769632936,
0.021004555746912956,
-0.009599391371011734,
-0.03773605450987816,
-0.04434746876358986,
0.034302718937397,
-0.044402096420526505,
0.06747088581323624,
0.04127971827983856,
0.023672064766287804,
-0.0321393683552742,
0.0425572395324707,
-0.03831036016345024,
0.06065521389245987,
-0.015098103322088718,
-0.024930495768785477,
0.02079465426504612,
0.006368566770106554,
0.0034059796016663313,
-0.02228127233684063,
0.10412924736738205,
-0.009337853640317917,
0.03309844434261322,
0.04044511541724205,
0.02743588201701641,
0.004946191795170307,
0.02191268466413021,
0.07930964976549149,
-0.02503839135169983,
-0.08312581479549408,
0.03876788169145584,
0.01120215654373169,
-0.12188609689474106,
-0.0976497158408165,
0.042829982936382294,
-0.036067765206098557,
-0.03554106131196022,
0.04572341591119766,
0.02241816371679306,
-0.0577896423637867,
0.02742696739733219,
0.08234252035617828,
0.02543449029326439,
-2.4832395302937596e-33,
0.016582388430833817,
-0.02582242526113987,
0.06019286438822746,
-0.06339772045612335,
-0.04613650217652321,
-0.03197268396615982,
0.0713675394654274,
-0.08080971986055374,
-0.0011915838113054633,
0.015301291830837727,
0.11140584945678711,
0.07452940195798874,
-0.08078659325838089,
-0.06511104851961136,
0.014240470714867115,
-0.058041974902153015,
0.042753297835588455,
0.03217257931828499,
-0.018027955666184425,
-0.053251445293426514,
0.041764285415410995,
0.05271878093481064,
-0.0036218599416315556,
0.12249574065208435,
0.01033379603177309,
0.021580619737505913,
0.09165835380554199,
0.0007483155350200832,
-0.016079427674412727,
0.06459774076938629,
-0.026744341477751732,
0.04848943650722504,
-0.025625137612223625,
-0.03232180327177048,
-0.040004514157772064,
-0.01535873208194971,
-0.06167233735322952,
0.049757398664951324,
-0.04288392886519432,
-0.01224149577319622,
0.02814285084605217,
0.07223279774188995,
0.03024151176214218,
-0.02520316280424595,
0.09782686829566956,
0.07810169458389282,
0.06472328305244446,
-0.07242085784673691,
-0.06376007199287415,
-0.0029028640128672123,
-0.07350217550992966,
0.03779315575957298,
0.00820896029472351,
0.06629929691553116,
0.03492783382534981,
0.0853823646903038,
-0.05891769006848335,
-0.006394395604729652,
0.02152221091091633,
-0.05624973773956299,
-0.044519130140542984,
-0.012656177394092083,
0.016527505591511726,
-0.005687741097062826,
-0.055815547704696655,
-0.0225585475564003,
0.06570769101381302,
0.06000911816954613,
0.08984532207250595,
0.012580359354615211,
0.02278456650674343,
0.06469856202602386,
0.03680761158466339,
0.07329773902893066,
-0.025043709203600883,
0.0358392596244812,
-0.07799609750509262,
-0.08760784566402435,
-0.03313613310456276,
-0.0630970373749733,
-0.022251686081290245,
0.04868637025356293,
-0.08619857579469681,
-0.03395780175924301,
0.02976364456117153,
-0.030080454424023628,
0.020014092326164246,
0.09299539029598236,
-0.01992582529783249,
-0.060028865933418274,
0.03766322508454323,
-0.06298162788152695,
-0.049818336963653564,
0.059764400124549866,
0.052058957517147064,
-3.563825856645053e-8,
-0.02875739522278309,
-0.03725981339812279,
0.04788608103990555,
-0.03416047245264053,
-0.07863829284906387,
0.04504122957587242,
-0.04118870198726654,
0.06587699055671692,
0.04843835160136223,
-0.0032539782114326954,
-0.01274418830871582,
0.047246452420949936,
0.060427337884902954,
0.03706680238246918,
0.00598096800968051,
0.0826239287853241,
-0.05360369011759758,
-0.06245959550142288,
-0.040948741137981415,
-0.07751733809709549,
-0.05215946212410927,
-0.06800312548875809,
-0.0046509746462106705,
-0.009664659388363361,
-0.017894327640533447,
-0.05296368524432182,
-0.12082958221435547,
0.0761578232049942,
-0.03420241177082062,
-0.05830274522304535,
0.004640690982341766,
0.004856931511312723,
-0.017938870936632156,
0.020263997837901115,
0.0608200766146183,
0.06846794486045837,
0.01909632794559002,
-0.04184844717383385,
0.008993434719741344,
0.022668758407235146,
0.02716635726392269,
-0.10388505458831787,
0.020543666556477547,
0.04848223924636841,
0.006091018673032522,
0.017300058156251907,
0.03437158837914467,
0.005085386335849762,
-0.007936247624456882,
-0.07667192816734314,
0.039462875574827194,
-0.0028962171636521816,
-0.07050054520368576,
-0.08954648673534393,
-0.08666901290416718,
0.023843854665756226,
-0.11014974117279053,
0.037243664264678955,
0.00526942266151309,
-0.05880476534366608,
0.01510818675160408,
-0.032867155969142914,
-0.012785078026354313,
-0.06355553865432739
] |
PMID:9548812 | Summation of the data on the sensitivity of DeltaMT1 to various hydroxamate inhibitors indicates that (1) the volume of the S1' subsite of DeltaMT1 is similar to that of MMP-2, -3, and -9, which is bigger than that of MMP-1, and (2) the S1 and S2' subsites are narrower than those in other MMPs. | [
0.0002669241512194276,
-0.10994644463062286,
0.026308659464120865,
-0.04288515821099281,
0.016692714765667915,
-0.03367457911372185,
-0.03611280024051666,
0.17274592816829681,
-0.015732092782855034,
-0.057324789464473724,
0.0025050893891602755,
-0.01784440502524376,
0.031502895057201385,
0.022925930097699165,
-0.07272861897945404,
0.02389833889901638,
0.11321014165878296,
0.012471132911741734,
0.00876303855329752,
0.06790763139724731,
0.0010955295292660594,
-0.05021389573812485,
-0.015702975913882256,
0.042509812861680984,
-0.006969695445150137,
0.08670991659164429,
-0.06666173785924911,
0.1075681820511818,
0.04768208786845207,
-0.08598816394805908,
0.04200790077447891,
0.09616947919130325,
0.0819404274225235,
-0.06571000814437866,
0.03313571959733963,
-0.026878174394369125,
-0.053115833550691605,
0.029506327584385872,
-0.028011763468384743,
0.024524951353669167,
0.07293267548084259,
-0.021939443424344063,
0.06522515416145325,
-0.06064493581652641,
-0.025050021708011627,
-0.10327467322349548,
-0.055604010820388794,
0.006333166733384132,
-0.07761310786008835,
0.08592218905687332,
0.02583078108727932,
-0.09100645035505295,
-0.060253024101257324,
0.057664405554533005,
-0.04426293820142746,
-0.058180585503578186,
-0.06776348501443863,
0.11279618740081787,
-0.010180479846894741,
-0.015487723983824253,
-0.015259828418493271,
0.08478707820177078,
-0.004502014722675085,
0.0012277233181521297,
0.10314325243234634,
0.0012523283949121833,
0.016696255654096603,
-0.10821044445037842,
-0.005267770495265722,
0.03668631613254547,
-0.04482389986515045,
-0.00993844773620367,
-0.04522010311484337,
0.019263969734311104,
-0.058505475521087646,
-0.027733366936445236,
-0.03600365296006203,
0.028398098424077034,
0.024956775829195976,
-0.03169488534331322,
0.011515028774738312,
-0.005850822664797306,
0.030275223776698112,
0.01411721296608448,
-0.003238117787986994,
0.010241026990115643,
0.01056640688329935,
0.07747684419155121,
0.0634843036532402,
-0.06878168135881424,
0.04197124019265175,
0.04506824165582657,
-0.03405047580599785,
0.04692871868610382,
-0.011718872003257275,
0.019261570647358894,
-0.09644021838903427,
0.06242573633790016,
0.03110245242714882,
-0.027392810210585594,
0.04724086821079254,
0.04850839823484421,
-0.1419498175382614,
0.0010327636264264584,
0.037916626781225204,
-0.001599260256625712,
0.03638717159628868,
0.016218215227127075,
-0.009384093806147575,
-0.0072593363001942635,
-0.029131339862942696,
-0.012914486229419708,
0.03667519614100456,
0.07512025535106659,
0.033298954367637634,
0.0060680340975522995,
0.09040510654449463,
0.0010856385342776775,
0.03700333088636398,
-0.063613161444664,
0.017754361033439636,
-0.09355062991380692,
-0.03769129887223244,
-0.0598333440721035,
0.062297891825437546,
0.06790269166231155,
-0.061218101531267166,
2.4757068155568966e-33,
0.026900721713900566,
-0.025248562917113304,
0.03856569528579712,
0.012712044641375542,
0.0028521802742034197,
-0.006847341079264879,
0.017074519768357277,
-0.06527440249919891,
-0.08147569000720978,
0.016087990254163742,
-0.12306170165538788,
0.0388297438621521,
-0.005153707228600979,
0.04373161867260933,
-0.034221991896629333,
-0.0320199579000473,
0.06395627558231354,
-0.017556538805365562,
0.030385887250304222,
-0.13471008837223053,
0.027630804106593132,
0.02727862074971199,
-0.0590360127389431,
0.0031255793292075396,
0.01130614336580038,
0.04446907341480255,
-0.009305791929364204,
0.08321979641914368,
-0.0031982241198420525,
-0.020565373823046684,
-0.07698393613100052,
-0.0237688310444355,
-0.07407527416944504,
0.03678399696946144,
-0.03938337787985802,
0.04254684969782829,
-0.001186210778541863,
-0.040967993438243866,
0.027320649474859238,
-0.0326312780380249,
-0.024326007813215256,
0.040640104562044144,
0.014098522253334522,
-0.09498851001262665,
0.0686502456665039,
-0.01596667431294918,
-0.1068873181939125,
-0.05552518367767334,
0.0064777228981256485,
0.006133540999144316,
0.02017299272119999,
0.004475014749914408,
0.014167052693665028,
0.023511527106165886,
-0.03159644827246666,
0.02355196140706539,
-0.06290486454963684,
0.04880412295460701,
-0.005122290458530188,
0.07769685238599777,
-0.0321364589035511,
-0.013871295377612114,
-0.012311344034969807,
0.019469093531370163,
0.0394628681242466,
0.07706744968891144,
-0.009153767488896847,
-0.0451025515794754,
0.0066628349013626575,
0.018521521240472794,
-0.06352134048938751,
-0.012937759980559349,
0.09591703116893768,
0.046341169625520706,
0.04568176344037056,
-0.0439518541097641,
0.05867050588130951,
0.05377528443932533,
0.036747291684150696,
0.06294369697570801,
-0.04274587705731392,
-0.047422654926776886,
-0.012661810033023357,
0.025386106222867966,
-0.13054104149341583,
-0.07248548418283463,
0.024830901995301247,
-0.052977412939071655,
-0.047937583178281784,
0.011953833512961864,
0.08327953517436981,
-0.07241910696029663,
-0.047542400658130646,
0.04253605753183365,
0.023746168240904808,
-4.6349253688083236e-33,
-0.02048637345433235,
0.019258534535765648,
0.04502264782786369,
0.0005672948900610209,
-0.06541077792644501,
0.038881298154592514,
0.10097604990005493,
-0.014437836594879627,
0.05754881724715233,
0.006941752973943949,
0.10273427516222,
0.05066933482885361,
-0.05572080612182617,
-0.12742328643798828,
-0.007367119193077087,
-0.0004609776951838285,
0.060011543333530426,
-0.02423701621592045,
0.007941244170069695,
-0.055998269468545914,
-0.004062475170940161,
0.08837273716926575,
-0.027126271277666092,
0.08315511792898178,
-0.009164436720311642,
0.011692259460687637,
0.03192109987139702,
-0.009054419584572315,
-0.010945437476038933,
0.02114296890795231,
-0.02618238888680935,
0.04603824019432068,
-0.03970615193247795,
-0.040943823754787445,
-0.01750025898218155,
-0.07178770005702972,
-0.07505489140748978,
0.026758737862110138,
-0.05001523345708847,
-0.0433414988219738,
-0.014013675972819328,
0.010184766724705696,
0.013007225468754768,
-0.0359661765396595,
0.08298201858997345,
0.07956477999687195,
0.030990106984972954,
-0.100364089012146,
0.03693648800253868,
-0.049738526344299316,
-0.0667305588722229,
0.0029493493493646383,
0.009567318484187126,
0.04053673520684242,
0.09769963473081589,
0.0020622441079467535,
0.036611199378967285,
-0.005547644104808569,
-0.007042214274406433,
0.012622258625924587,
-0.006234845146536827,
0.059161726385354996,
-0.036786194890737534,
0.0007376421708613634,
-0.02622084692120552,
0.13176468014717102,
-0.013247157447040081,
-0.004732847213745117,
0.08765445649623871,
0.02759920246899128,
0.02978384867310524,
0.022915950044989586,
0.07672253251075745,
0.018976932391524315,
-0.041736505925655365,
-0.03724987059831619,
-0.030434880405664444,
0.0018048286437988281,
-0.032455187290906906,
-0.09624158591032028,
0.026597343385219574,
0.06570565700531006,
-0.02824336476624012,
-0.0685819759964943,
-0.05083579570055008,
-0.021910179406404495,
-0.004208394326269627,
0.0745263546705246,
0.032845452427864075,
-0.018566029146313667,
0.0024739974178373814,
-0.04768825322389603,
-0.03643574193120003,
-0.015302383340895176,
0.05333936959505081,
-4.544321896560177e-8,
0.020814567804336548,
-0.08244359493255615,
-0.006457151845097542,
-0.030050380155444145,
-0.07069909572601318,
0.08067735284566879,
-0.07603850960731506,
0.07350519299507141,
0.04866898059844971,
0.06443516165018082,
0.028244495391845703,
0.041589174419641495,
-0.02290268801152706,
-0.00850007962435484,
-0.0061015114188194275,
-0.016686785966157913,
-0.03140026703476906,
-0.02675093524158001,
-0.008572973310947418,
-0.07609659433364868,
-0.04609546437859535,
-0.002603992586955428,
0.008937506936490536,
-0.04801333323121071,
0.0883045420050621,
0.005355475004762411,
-0.09053216129541397,
0.055430710315704346,
0.042993009090423584,
-0.023481348529458046,
0.04083235561847687,
0.01595299504697323,
0.0408782884478569,
0.04643809050321579,
0.023369187489151955,
0.003963231109082699,
-0.009847140870988369,
0.030795160681009293,
0.0019333120435476303,
0.03773588314652443,
0.017562447115778923,
-0.1121847927570343,
-0.017865996807813644,
-0.037388671189546585,
0.010598608292639256,
0.0202060267329216,
0.02103562094271183,
-0.005447587929666042,
-0.004077146295458078,
-0.09224224090576172,
0.024913262575864792,
0.03188387304544449,
-0.08892927318811417,
-0.09747980535030365,
-0.025228211656212807,
-0.00015004137821961194,
-0.0701821818947792,
-0.0499253049492836,
-0.03415549919009209,
-0.10379667580127716,
-0.028015127405524254,
-0.08475387096405029,
0.0019845208153128624,
-0.014459291473031044
] |
PMID:9548812 | On the basis of these results, the hydroxamates with a P1' phenylpropyl and P2' alpha-branched alkyl group were synthesized and evaluated for inhibitory activity. | [
-0.01942768320441246,
-0.1278112530708313,
-0.026278642937541008,
0.010837260633707047,
0.02507953718304634,
0.0660879909992218,
-0.049463458359241486,
-0.016032906249165535,
0.0585767887532711,
-0.012820795178413391,
0.02067108266055584,
0.051944196224212646,
-0.0074128261767327785,
0.0698549896478653,
-0.031343135982751846,
0.09965945780277252,
-0.05146876722574234,
0.04014621675014496,
0.044795528054237366,
0.05491767078638077,
-0.025575213134288788,
-0.0038763736374676228,
0.06179935485124588,
0.07072845846414566,
-0.058247145265340805,
0.07552988082170486,
0.031714506447315216,
0.0720546767115593,
0.04134119674563408,
-0.07959364354610443,
0.11881473660469055,
0.009908732026815414,
0.06405135989189148,
-0.06710954010486603,
-0.07515052706003189,
0.016325777396559715,
-0.05289767310023308,
-0.05553104728460312,
-0.004279639106243849,
0.019435938447713852,
0.1076684296131134,
-0.06217010319232941,
-0.023048117756843567,
-0.05775747075676918,
-0.0008269859827123582,
-0.07745454460382462,
-0.03335091099143028,
-0.038070198148489,
0.015574808232486248,
0.0897870659828186,
0.01359820831567049,
-0.0596480630338192,
-0.010183243080973625,
0.04124360531568527,
-0.041862912476062775,
0.01782306656241417,
-0.06062052398920059,
0.09235746413469315,
0.038258906453847885,
0.011720008216798306,
0.036749452352523804,
0.09065590053796768,
0.03191319480538368,
-0.002951410599052906,
-0.11880379170179367,
0.011982313357293606,
-0.06015923246741295,
-0.028159305453300476,
0.04516797885298729,
0.02952679805457592,
-0.10062896460294724,
-0.07467152923345566,
0.08725948631763458,
0.007354978006333113,
-0.056170504540205,
-0.00610014796257019,
0.03416333347558975,
-0.0567338801920414,
-0.008705365471541882,
-0.041947346180677414,
-0.006490394007414579,
-0.09919968992471695,
0.03874797001481056,
0.11111973971128464,
0.04562399908900261,
0.023524370044469833,
0.02992047742009163,
-0.005550425965338945,
0.044126760214567184,
-0.07795928418636322,
0.03200581669807434,
0.07115828990936279,
0.0019467181991785765,
0.013185986317694187,
0.07108978182077408,
0.056820668280124664,
-0.027770189568400383,
-0.012173369526863098,
-0.01447552815079689,
0.012505284510552883,
0.0071210479363799095,
-0.020839614793658257,
-0.01833663135766983,
-0.09069116413593292,
0.017364535480737686,
0.006398365832865238,
0.008573622442781925,
-0.03517577424645424,
-0.004079125355929136,
-0.04848872870206833,
-0.05773172155022621,
-0.07435309886932373,
0.008281141519546509,
0.0310378260910511,
-0.03480679541826248,
0.018867280334234238,
0.021941017359495163,
-0.021292444318532944,
-0.004757042974233627,
-0.07287056744098663,
0.013018541038036346,
-0.03787427023053169,
0.08765473961830139,
0.043249815702438354,
-0.030450785532593727,
-0.013791762292385101,
-0.03994892165064812,
-5.328029164147792e-34,
0.008348912931978703,
0.009293151088058949,
-0.017197493463754654,
0.02858688496053219,
0.0030201307963579893,
-0.044093843549489975,
-0.06732762604951859,
-0.03259587287902832,
-0.04219953715801239,
-0.06555958092212677,
-0.033535923808813095,
0.014879130758345127,
0.0056718322448432446,
0.05166425183415413,
0.025128882378339767,
-0.06627760082483292,
0.08322640508413315,
-0.0005732744466513395,
0.03997030481696129,
-0.07505014538764954,
0.04886528104543686,
0.01188890915364027,
-0.0626850500702858,
0.0517130121588707,
-0.032851241528987885,
-0.05670841410756111,
-0.022184250876307487,
-0.033179156482219696,
0.05805441364645958,
-0.03718109056353569,
-0.01946084573864937,
-0.02555573545396328,
-0.0761614590883255,
0.040806397795677185,
-0.053978513926267624,
0.003202535677701235,
-0.07763450592756271,
-0.0670141652226448,
0.03836945444345474,
-0.007139505818486214,
-0.019164886325597763,
-0.004910796880722046,
0.031120628118515015,
-0.09088699519634247,
0.027095407247543335,
0.02495126612484455,
-0.04276873916387558,
0.047160983085632324,
0.01908387616276741,
-0.007563950959593058,
0.07565202564001083,
0.008998401463031769,
-0.040364474058151245,
0.0962720587849617,
-0.10503611713647842,
0.009021086618304253,
-0.07568645477294922,
0.025124164298176765,
0.04841850697994232,
0.04586810618638992,
-0.024353167042136192,
0.005078365560621023,
-0.027917619794607162,
-0.024383747950196266,
-0.03832971677184105,
0.03855836018919945,
0.0671631246805191,
0.009825028479099274,
-0.03790312632918358,
-0.01563873328268528,
-0.013686171732842922,
0.036396272480487823,
0.09890791028738022,
0.06640727818012238,
0.046238817274570465,
-0.0007556378259323537,
0.025718331336975098,
0.001925971475429833,
0.0423247329890728,
0.12822678685188293,
0.009545505046844482,
-0.023612676188349724,
-0.03545206040143967,
0.06617990136146545,
-0.03866543620824814,
0.005928273778408766,
0.0009530014940537512,
0.03276151418685913,
-0.008485761471092701,
0.05448640137910843,
0.05761713907122612,
-0.08564271777868271,
-0.016196854412555695,
0.0368489995598793,
0.029919439926743507,
-1.5756216075826552e-33,
0.05964997410774231,
-0.080387644469738,
0.04339498281478882,
-0.030958712100982666,
0.009855400770902634,
-0.01158357597887516,
0.06819920241832733,
-0.1215670257806778,
0.08170264214277267,
0.011756871826946735,
0.1066618263721466,
0.0048001729883253574,
-0.01322451513260603,
-0.07584525644779205,
-0.030368896201252937,
0.01698504388332367,
0.0185121800750494,
-0.02958369068801403,
0.0007469846168532968,
-0.05908436328172684,
0.06853721290826797,
-0.019231554120779037,
0.03702933341264725,
0.03662967309355736,
0.013859601691365242,
0.020733147859573364,
0.08625484257936478,
-0.05435316264629364,
0.03732798248529434,
0.12430232763290405,
-0.027515685185790062,
0.06857872009277344,
-0.06785111129283905,
-0.06898102909326553,
0.03422422334551811,
0.0552242286503315,
-0.10612199455499649,
-0.0016853166744112968,
-0.07185199111700058,
-0.060338448733091354,
0.018873482942581177,
0.0028811395168304443,
-0.018846049904823303,
-0.010317723266780376,
0.05654716491699219,
0.0875648632645607,
0.028355484828352928,
-0.039001964032649994,
-0.04057694226503372,
-0.023440996184945107,
-0.0364939384162426,
0.14179714024066925,
-0.0387931689620018,
-0.009347341023385525,
0.020856404677033424,
0.01807074435055256,
0.021066855639219284,
-0.03182714059948921,
0.016999710351228714,
-0.047705695033073425,
-0.046664055436849594,
0.015061885118484497,
0.05677715688943863,
-0.03409908711910248,
-0.09105145931243896,
0.0741758644580841,
-0.011406990699470043,
0.1221318319439888,
0.07308541238307953,
-0.04683045670390129,
0.06373366713523865,
0.014625978656113148,
0.0797441303730011,
0.08478355407714844,
-0.016624201089143753,
0.013636873103678226,
0.02048276551067829,
-0.07060031592845917,
-0.04943288117647171,
-0.059585049748420715,
0.044392164796590805,
0.03919172286987305,
-0.019075928255915642,
-0.056587040424346924,
-0.08270710706710815,
0.034290969371795654,
0.016375213861465454,
0.051690950989723206,
-0.01812436245381832,
-0.02778407372534275,
0.067794069647789,
-0.045651569962501526,
-0.016256988048553467,
0.06414353102445602,
0.038725174963474274,
-3.2895531631993435e-8,
-0.07582812756299973,
-0.008498379960656166,
0.059766706079244614,
-0.07604815065860748,
-0.03197101876139641,
0.026285773143172264,
-0.023461103439331055,
0.04562046378850937,
-0.03715307638049126,
-0.08590234071016312,
-0.02092588320374489,
-0.0005022040568292141,
0.014477109536528587,
0.023567944765090942,
-0.054286181926727295,
0.05093406140804291,
-0.0362338088452816,
-0.014461219310760498,
0.011513780802488327,
-0.07272262871265411,
-0.04256045073270798,
0.0206832904368639,
-0.07457900047302246,
0.03917105868458748,
-0.02032448910176754,
-0.02696835622191429,
-0.012398643419146538,
-0.021806584671139717,
-0.015705440193414688,
-0.06351232528686523,
0.014030109159648418,
0.05548485741019249,
-0.06246424466371536,
0.03805995732545853,
0.10481902211904526,
0.06603067368268967,
-0.0005690543330274522,
-0.0021840124391019344,
-0.0922136977314949,
0.02988571487367153,
0.016658896580338478,
-0.05478353798389435,
0.06356694549322128,
-0.026127170771360397,
0.020764682441949844,
0.023489290848374367,
-0.017650749534368515,
-0.023706402629613876,
0.026027509942650795,
-0.04853557050228119,
0.056183721870183945,
0.019681012257933617,
-0.025415385141968727,
-0.04659917950630188,
-0.060587357729673386,
0.039278920739889145,
-0.056810103356838226,
-0.10663150995969772,
-0.06645884364843369,
-0.10925063490867615,
-0.050240691751241684,
-0.08353840559720993,
0.08101669698953629,
-0.0077664777636528015
] |
PMID:9548812 | These inhibitors (1h,i) showed strong activity against DeltaMT1 over MMP-1, but no selectivity between DeltaMT1 and MMP-9. | [
-0.04603953659534454,
-0.07259254157543182,
0.042635221034288406,
-0.02662906050682068,
0.017387088388204575,
0.015704182907938957,
-0.03283710405230522,
0.09237246960401535,
-0.04841817542910576,
-0.025088738650083542,
0.029489513486623764,
-0.017272312194108963,
-0.024486880749464035,
0.031237851828336716,
0.019368276000022888,
0.08014557510614395,
0.03945879265666008,
-0.018021587282419205,
0.05490850284695625,
0.02858329564332962,
-0.06741438060998917,
-0.016536537557840347,
0.011177231557667255,
0.008177658542990685,
0.042537130415439606,
0.06351392716169357,
-0.03195401281118393,
0.06917120516300201,
0.040648989379405975,
-0.06525782495737076,
0.02016722969710827,
0.048121657222509384,
0.021686645224690437,
0.028156591579318047,
0.014623519033193588,
-0.003673003753647208,
-0.07432340085506439,
0.022915849462151527,
-0.09255018085241318,
-0.03519896790385246,
0.08307661861181259,
-0.037566106766462326,
0.05364587530493736,
-0.07948414236307144,
-0.026265116408467293,
-0.10910812020301819,
-0.044548965990543365,
0.05085998773574829,
-0.061580315232276917,
0.1014050766825676,
-0.0008919318206608295,
0.0037737474776804447,
-0.05313673987984657,
0.06863328069448471,
0.012013731524348259,
-0.07593460381031036,
-0.11686069518327713,
0.14826516807079315,
-0.014140503481030464,
-0.02116611786186695,
-0.01367430854588747,
0.08410024642944336,
-0.017549358308315277,
-0.012681622989475727,
0.05251581221818924,
0.036227885633707047,
0.027538074180483818,
-0.05176771432161331,
0.027442961931228638,
0.04598991200327873,
0.0012320410460233688,
-0.04931651055812836,
-0.0385257713496685,
0.009376399219036102,
-0.04378286004066467,
0.04152638837695122,
-0.011066903360188007,
-0.0006711500464007258,
-0.0006143226637504995,
-0.03538118675351143,
-0.003156326711177826,
-0.013489645905792713,
0.08110108226537704,
0.005687754135578871,
-0.00578338885679841,
0.028099799528717995,
-0.04468202218413353,
0.14093782007694244,
0.05887027829885483,
-0.06500866264104843,
0.09447187185287476,
0.0675407350063324,
-0.040760572999715805,
0.004525083117187023,
-0.00145826768130064,
0.0005676123546436429,
-0.09648735821247101,
0.07176591455936432,
-0.01931023597717285,
-0.0008646586211398244,
0.036319978535175323,
0.04313741251826286,
-0.1413944661617279,
0.031078433617949486,
-0.021536435931921005,
-0.006661378312855959,
0.07024659961462021,
-0.06684807687997818,
-0.03863615542650223,
-0.026763619855046272,
0.037792664021253586,
-0.048331912606954575,
0.017543397843837738,
0.037577055394649506,
-0.015175899490714073,
-0.021247945725917816,
0.04932372272014618,
0.019491715356707573,
0.017675843089818954,
-0.018989380449056625,
0.0014373792801052332,
-0.08834286034107208,
0.029162121936678886,
-0.05674589425325394,
-0.04449325427412987,
0.10153046995401382,
-0.05434698611497879,
2.0193147053654124e-33,
0.009411918930709362,
-0.04148656502366066,
0.021304644644260406,
0.004033199045807123,
0.031246669590473175,
-0.022867105901241302,
-0.013080987147986889,
-0.08267555385828018,
-0.07601495087146759,
-0.03018249198794365,
-0.07379506528377533,
-0.024834156036376953,
0.012523552402853966,
0.01726670190691948,
-0.020923614501953125,
-0.009539829567074776,
0.022420767694711685,
-0.043706074357032776,
0.083545982837677,
-0.11013413965702057,
0.029567934572696686,
0.07989711314439774,
-0.06025451794266701,
-0.05476944521069527,
-0.000006920303349033929,
0.06980130076408386,
0.005588561296463013,
0.10898196697235107,
-0.017387647181749344,
-0.013591674156486988,
-0.0870361253619194,
-0.016072850674390793,
-0.10977616906166077,
-0.018444446846842766,
-0.03230779245495796,
0.07802402228116989,
-0.033554814755916595,
-0.055997200310230255,
0.005649528931826353,
-0.049931738525629044,
-0.03491247072815895,
0.027527378872036934,
-0.033605434000492096,
-0.0928700715303421,
0.035615529865026474,
-0.06953217834234238,
-0.09945834428071976,
-0.024846412241458893,
-0.011911534704267979,
0.010437843389809132,
0.02522154152393341,
-0.022595666348934174,
-0.008818874135613441,
0.03140769153833389,
-0.018375005573034286,
0.022287460044026375,
-0.02112978883087635,
0.08036395907402039,
0.0003955366264563054,
0.09015260636806488,
0.0009188539697788656,
-0.02566775120794773,
-0.02628660388290882,
-0.005939789116382599,
0.023118600249290466,
0.037194009870290756,
-0.023127224296331406,
0.004439325071871281,
-0.02138904295861721,
0.024162521585822105,
-0.027189813554286957,
-0.050700753927230835,
0.09488030523061752,
-0.004866679199039936,
0.07547461986541748,
0.03021056018769741,
0.06831318885087967,
0.0679575726389885,
0.004546619486063719,
0.05196861922740936,
0.02590564265847206,
-0.09705304354429245,
-0.012385443784296513,
0.015380571596324444,
-0.07223347574472427,
-0.060173362493515015,
0.0016020021867007017,
-0.06839559972286224,
0.00009922379831550643,
-0.0027319027576595545,
0.09352511912584305,
0.028571147471666336,
-0.0035669030621647835,
0.07671422511339188,
-0.02845017798244953,
-3.6819208745280014e-33,
-0.020283767953515053,
0.024078307673335075,
0.10007534921169281,
-0.023738209158182144,
-0.10912828892469406,
0.04288744553923607,
0.04274861887097359,
-0.09959567338228226,
0.0687004029750824,
0.004788519348949194,
0.10542600601911545,
-0.012256198562681675,
-0.05336429178714752,
-0.1299571841955185,
-0.032797038555145264,
-0.047609005123376846,
0.07058422267436981,
0.02666003443300724,
0.01039485540241003,
0.03871454671025276,
-0.025095786899328232,
0.10513081401586533,
-0.052552029490470886,
0.08052640408277512,
-0.05427975580096245,
0.014470688067376614,
0.07699362188577652,
0.032221719622612,
0.021575985476374626,
0.044069886207580566,
0.004959207959473133,
0.040064699947834015,
-0.050788890570402145,
-0.09651349484920502,
0.012051700614392757,
-0.04706971347332001,
-0.020552154630422592,
0.026265239343047142,
-0.03676723688840866,
-0.024429621174931526,
0.03426232188940048,
0.05908830836415291,
-0.021273445338010788,
-0.010195489041507244,
0.033572424203157425,
0.0315181240439415,
0.02543915994465351,
-0.04123009741306305,
-0.04814561828970909,
-0.06573852151632309,
-0.05690940096974373,
0.026463698595762253,
0.007496203295886517,
-0.011063135229051113,
0.05968494713306427,
0.013650698587298393,
0.07615121454000473,
0.008997353725135326,
0.04397043585777283,
0.020563317462801933,
-0.036978624761104584,
0.035644806921482086,
-0.020602796226739883,
0.010177585296332836,
0.06011053919792175,
0.10103436559438705,
0.08862249553203583,
0.041122548282146454,
0.05052752047777176,
-0.03904576599597931,
0.005665165837854147,
0.05631708726286888,
0.060928795486688614,
0.042432986199855804,
-0.014334381558001041,
0.035346172749996185,
-0.044028520584106445,
-0.04696037992835045,
0.019597910344600677,
-0.09129932522773743,
0.05344528332352638,
-0.0058699375949800014,
-0.06427454203367233,
-0.07909771054983139,
0.002936444478109479,
0.027560079470276833,
-0.002641259226948023,
0.06439719349145889,
0.06901922821998596,
-0.0021008746698498726,
0.02179013192653656,
-0.047517865896224976,
-0.03876812383532524,
0.025708777830004692,
-0.008178099058568478,
-2.7600677299233212e-8,
0.054887380450963974,
-0.09637882560491562,
0.036252859979867935,
-0.05199897289276123,
-0.10116444528102875,
0.006711443420499563,
-0.048863109201192856,
0.030376214534044266,
0.03444317355751991,
0.050834886729717255,
0.028460504487156868,
0.026925161480903625,
-0.02970306947827339,
-0.013400686904788017,
0.05367101728916168,
-0.030871745198965073,
-0.023558441549539566,
-0.028077423572540283,
-0.031578920781612396,
-0.020649952813982964,
-0.0678301751613617,
-0.01734897308051586,
0.0753520205616951,
-0.056899938732385635,
0.042470451444387436,
-0.015195665881037712,
-0.09188511222600937,
0.06196191534399986,
0.07596264779567719,
-0.03402116522192955,
0.00032416346948593855,
0.029583992436528206,
0.04271929711103439,
-0.012906432151794434,
0.01641944982111454,
0.020531466230750084,
0.05979664996266365,
-0.006590810604393482,
0.017003577202558517,
0.058591991662979126,
0.01115356758236885,
-0.03891585394740105,
-0.012755095958709717,
-0.023849179968237877,
-0.043700091540813446,
0.008343865163624287,
0.046572450548410416,
-0.02114991843700409,
-0.06617462635040283,
-0.08995429426431656,
0.01042176689952612,
0.048044316470623016,
-0.05135435238480568,
-0.12538577616214752,
-0.09858537465333939,
-0.04162595421075821,
-0.03205325827002525,
0.04969983547925949,
0.042620278894901276,
-0.09400191158056259,
-0.00833652913570404,
-0.11611020565032959,
-0.020271632820367813,
-0.0245639868080616
] |
PMID:9548812 | These results are explained using molecular modeling studies conducted on MT1-MMP. | [
-0.11030513048171997,
-0.10270426422357559,
0.11012253910303116,
0.04094311222434044,
0.011129404418170452,
-0.04704951122403145,
-0.059640172868967056,
0.10010597109794617,
-0.010483765043318272,
0.009764823131263256,
0.012150485068559647,
-0.0250378530472517,
0.052331797778606415,
0.020239362493157387,
-0.023038167506456375,
0.031100546941161156,
-0.014099557884037495,
0.005609698593616486,
0.08606304228305817,
0.060876183211803436,
0.06655039638280869,
0.006792036350816488,
-0.06519799679517746,
-0.04332713410258293,
0.01977415569126606,
0.044496193528175354,
-0.017652874812483788,
0.1005069836974144,
0.01619642600417137,
-0.023208407685160637,
0.0364241898059845,
0.04255715012550354,
0.0077697173692286015,
-0.04495830833911896,
0.04757379740476608,
0.058379724621772766,
-0.05905377119779587,
-0.010263272561132908,
-0.10495390743017197,
-0.02316814288496971,
0.07554652541875839,
0.008549290709197521,
0.1025010496377945,
-0.05581045523285866,
0.06274042278528214,
-0.11708251386880875,
-0.01664232276380062,
0.04273353889584541,
-0.06750059127807617,
0.08039313554763794,
0.03102313168346882,
0.0012727316934615374,
-0.056117188185453415,
0.02766036055982113,
-0.03354417160153389,
-0.09127966314554214,
-0.1239977777004242,
0.011274886317551136,
0.02698208950459957,
-0.003383243689313531,
-0.05874033272266388,
0.04193365201354027,
-0.049911241978406906,
-0.016039086505770683,
0.149145245552063,
0.002665614942088723,
0.0385357141494751,
-0.03260120376944542,
0.02549951709806919,
-0.00033452024217695,
-0.11437442153692245,
0.012646413408219814,
-0.04716290906071663,
0.027849923819303513,
-0.006768085528165102,
0.057183705270290375,
-0.020443076267838478,
-0.01576969400048256,
0.023751545697450638,
0.014717255719006062,
-0.04847085103392601,
0.03202182054519653,
0.037141352891922,
-0.062105968594551086,
0.0031629486475139856,
0.019534122198820114,
0.0438828207552433,
0.09008200466632843,
-0.05443582683801651,
-0.06374409794807434,
0.006646965630352497,
0.018338976427912712,
-0.05859995633363724,
0.07803983986377716,
-0.09433893859386444,
0.053450774401426315,
0.004208121914416552,
0.07373254001140594,
0.018432267010211945,
-0.009515447542071342,
0.033244501799345016,
0.0731540098786354,
-0.055045273154973984,
0.009763075970113277,
-0.009829443879425526,
-0.026203420013189316,
0.061483584344387054,
0.05219903215765953,
-0.03571563959121704,
0.012569848448038101,
0.06717884540557861,
0.07268986850976944,
-0.019301660358905792,
-0.027209462597966194,
0.060651745647192,
-0.034637387841939926,
-0.0043925936333835125,
0.01673593558371067,
0.00003785224907915108,
0.02007290907204151,
-0.05146156623959541,
-0.08417659252882004,
-0.026540648192167282,
-0.0377458781003952,
0.015479062683880329,
0.0310193058103323,
-0.019705692306160927,
-8.726128029695706e-34,
0.03437192365527153,
-0.031827639788389206,
0.06444139778614044,
0.021567337214946747,
0.04046620428562164,
-0.08795161545276642,
-0.02003655768930912,
-0.05643412098288536,
-0.07754191011190414,
-0.021408073604106903,
-0.05575726926326752,
-0.013900808058679104,
0.00954375695437193,
-0.00462948577478528,
-0.08362268656492233,
0.006369662005454302,
0.018270548433065414,
0.0049429237842559814,
0.12456674128770828,
-0.0565955676138401,
-0.027124227955937386,
0.04151215776801109,
0.04462723806500435,
0.01563650369644165,
0.00551745668053627,
0.038472436368465424,
-0.039843663573265076,
-0.01149276364594698,
-0.04717486724257469,
0.01296994835138321,
-0.03295176103711128,
-0.04740242287516594,
-0.1303994059562683,
-0.03229893371462822,
0.0017686624778434634,
0.0194109994918108,
-0.018695726990699768,
-0.07372131198644638,
0.044251665472984314,
-0.03138943016529083,
-0.07928627729415894,
-0.017851093783974648,
-0.019805900752544403,
-0.02260051853954792,
-0.06781665235757828,
-0.02865738980472088,
-0.03893252834677696,
-0.044535256922245026,
-0.009039286524057388,
0.006083460059016943,
0.021392671391367912,
0.03099812939763069,
0.00885611679404974,
0.018645426258444786,
-0.05574014410376549,
0.03099064715206623,
-0.03544987738132477,
-0.030407309532165527,
-0.03619612008333206,
0.09790794551372528,
0.04410967975854874,
0.02434707060456276,
0.0197796318680048,
0.02216673456132412,
0.08431399613618851,
0.006033711135387421,
-0.038371384143829346,
-0.004540732596069574,
0.049189697951078415,
0.04919157922267914,
0.027085190638899803,
-0.05087226629257202,
0.10242416709661484,
0.02733416110277176,
0.07061588019132614,
0.008453644812107086,
0.04703345522284508,
0.026645079255104065,
0.03766554966568947,
0.060951922088861465,
-0.03429845720529556,
-0.01993427239358425,
-0.041419804096221924,
-0.1418142318725586,
-0.1281398981809616,
-0.026213495060801506,
0.052012115716934204,
-0.12441031634807587,
0.010698437690734863,
0.011029073037207127,
0.13912813365459442,
0.05904453992843628,
0.024856191128492355,
0.016436411067843437,
-0.06405997276306152,
-2.0419692365706426e-33,
0.013403361663222313,
-0.00024049545754678547,
0.08966699987649918,
-0.012221847660839558,
-0.11568207293748856,
-0.022721748799085617,
0.004337149206548929,
-0.016397841274738312,
0.053350791335105896,
0.042747873812913895,
0.16495178639888763,
0.028650233522057533,
-0.02836393564939499,
-0.09150390326976776,
0.01106953714042902,
-0.040903713554143906,
0.051580529659986496,
0.006376937497407198,
0.07396449893712997,
0.017352376133203506,
0.005107829812914133,
0.06708984076976776,
-0.06227773800492287,
0.033076196908950806,
-0.058970723301172256,
-0.005902242846786976,
-0.02691967599093914,
-0.043420664966106415,
0.05467357486486435,
0.024762088432908058,
0.0027773757465183735,
0.09290128201246262,
-0.008639546111226082,
-0.028142651543021202,
0.017956670373678207,
0.01076069101691246,
-0.02384822443127632,
-0.012447637505829334,
0.06730910390615463,
0.019230857491493225,
0.058406710624694824,
0.07200533896684647,
-0.06402461975812912,
-0.09798362851142883,
0.057127173990011215,
-0.005739699117839336,
0.055103279650211334,
-0.016592634841799736,
0.08778376877307892,
-0.14309437572956085,
-0.013690094463527203,
0.03305123373866081,
-0.009146238677203655,
-0.059338126331567764,
0.015731416642665863,
0.025672804564237595,
-0.0019832546822726727,
-0.02147025056183338,
-0.0004984445404261351,
0.0011546268360689282,
-0.02080627903342247,
-0.04586752876639366,
-0.017927397042512894,
-0.025448709726333618,
-0.020640401169657707,
0.08957351744174957,
0.05016684532165527,
-0.012848927639424801,
0.006050508935004473,
0.009829587303102016,
0.0017016582423821092,
0.0237350445240736,
0.08829861134290695,
0.034061890095472336,
0.03231014311313629,
-0.025920340791344643,
-0.02986130118370056,
0.02010674774646759,
-0.04821568727493286,
-0.10821375995874405,
0.01860988140106201,
0.04063307121396065,
-0.07779446989297867,
-0.08416181057691574,
-0.02858809567987919,
-0.055701687932014465,
0.0391928106546402,
0.01849651336669922,
-0.05488823726773262,
-0.04141395911574364,
-0.03133493289351463,
-0.02472689375281334,
-0.04097940772771835,
0.0680166482925415,
-0.007803571876138449,
-2.326873627112036e-8,
0.0471884161233902,
-0.03889208287000656,
0.01775408163666725,
-0.026589887216687202,
-0.04153742268681526,
0.07925619184970856,
-0.04299594461917877,
-0.0011309616966173053,
0.08146266639232635,
0.0782637670636177,
0.0318681038916111,
0.00584584753960371,
-0.003786924062296748,
-0.03593761473894119,
0.03793281689286232,
0.026841552928090096,
-0.025434618815779686,
-0.02791573666036129,
-0.038069263100624084,
-0.02685992233455181,
0.029389312490820885,
0.02223086543381214,
0.021040726453065872,
0.009076917544007301,
0.03712868317961693,
-0.0013907768297940493,
-0.03515662997961044,
0.07421714067459106,
0.012169398367404938,
-0.01647433638572693,
-0.005788211245089769,
-0.01711830496788025,
0.01082524098455906,
0.036884572356939316,
0.03902009502053261,
0.02294904738664627,
0.05623463913798332,
0.030875282362103462,
0.005382551345974207,
0.08957003802061081,
-0.03479618579149246,
-0.008290279656648636,
-0.03564341738820076,
-0.01575295254588127,
-0.03175520524382591,
0.07316640019416809,
-0.004644865170121193,
0.04321913421154022,
-0.1336900293827057,
-0.04547622427344322,
-0.031061703339219093,
0.03773273527622223,
-0.08675704896450043,
-0.08052073419094086,
-0.029503487050533295,
0.020720424130558968,
-0.02766687609255314,
0.01660706102848053,
0.031153345480561256,
-0.10955639183521271,
-0.020834682509303093,
-0.06921841204166412,
-0.026662763208150864,
-0.039090871810913086
] |
PMID:27038494 | Novel Ilomastat analogs with substituted benzamide groups, instead of hydroxamic acid groups, were designed, synthesized and evaluated against MMP-2 and MMP-9. | [
-0.105397067964077,
-0.05770685523748398,
0.02396225556731224,
-0.0778060108423233,
0.001404905691742897,
0.01260873582214117,
-0.0022627210710197687,
0.15136803686618805,
0.061612196266651154,
0.011675970628857613,
0.02235739678144455,
-0.005640137940645218,
-0.07281268388032913,
-0.012471242807805538,
-0.04643223062157631,
0.10116611421108246,
0.09511037170886993,
0.08259381353855133,
0.09858974814414978,
0.023645984008908272,
-0.05726401135325432,
-0.05261969938874245,
0.011968882754445076,
-0.04086857661604881,
0.023590076714754105,
0.1217447891831398,
0.0902334600687027,
0.013513435609638691,
-0.07040134817361832,
-0.008239050395786762,
-0.0033960200380533934,
-0.07404473423957825,
-0.015292389318346977,
-0.11083890497684479,
-0.033734820783138275,
-0.00865632202476263,
-0.07627300918102264,
-0.03901614993810654,
-0.0019590831361711025,
0.024998530745506287,
0.05991600081324577,
0.0014551039785146713,
0.059428129345178604,
-0.05644733086228371,
-0.01653389073908329,
-0.07124718278646469,
-0.028946492820978165,
0.004904825706034899,
-0.06655878573656082,
0.10003850609064102,
-0.0036604241468012333,
-0.0019183759577572346,
0.009155427105724812,
-0.004746612627059221,
-0.09841925650835037,
-0.13004165887832642,
-0.1211601048707962,
0.0838552787899971,
-0.03183354437351227,
0.01750371791422367,
0.015054444782435894,
0.07998204976320267,
0.03407001867890358,
0.031038573011755943,
-0.06235763058066368,
0.05315779894590378,
-0.0598897784948349,
-0.031080765649676323,
0.013677340932190418,
0.007555519230663776,
-0.0768008604645729,
-0.007562743034213781,
0.025128860026597977,
-0.007037120871245861,
-0.011367534287273884,
0.05343683809041977,
0.02796449512243271,
-0.046460315585136414,
0.057850852608680725,
0.06749339401721954,
0.03221515566110611,
0.07146751135587692,
0.051289454102516174,
0.04342824965715408,
0.033778347074985504,
0.07788340747356415,
0.009268099442124367,
0.08283337950706482,
0.03145063295960426,
-0.033243924379348755,
0.04145250841975212,
0.0825626403093338,
0.0012075008125975728,
0.027990132570266724,
0.0027600391767919064,
-0.009451421909034252,
0.008853898383677006,
0.0859588086605072,
0.005292264278978109,
0.015492985025048256,
-0.005412548314779997,
0.09519719332456589,
-0.11192335188388824,
-0.06798159331083298,
-0.07607562094926834,
-0.03007858619093895,
0.020774193108081818,
-0.03653842210769653,
-0.00391142163425684,
-0.025782782584428787,
-0.01850540190935135,
-0.026438705623149872,
-0.06278824806213379,
-0.08008644729852676,
0.026151400059461594,
0.016600610688328743,
0.03163807466626167,
-0.02304360456764698,
0.04449370130896568,
-0.03517106547951698,
-0.027384594082832336,
-0.11347974091768265,
-0.003982586786150932,
0.019374171271920204,
0.052901238203048706,
0.10965162515640259,
-0.020827949047088623,
-3.940081658158646e-34,
-0.00989867839962244,
0.00952744297683239,
0.07023970782756805,
0.004769470077008009,
-0.053892627358436584,
-0.0025185728445649147,
-0.039656974375247955,
-0.10048570483922958,
-0.05830732360482216,
-0.05657801404595375,
-0.0920005738735199,
-0.07379097491502762,
-0.012332454323768616,
-0.0013326638145372272,
0.014435837976634502,
-0.011487942188978195,
0.05440177023410797,
-0.0005517277168110013,
0.09163051098585129,
-0.12012869119644165,
0.0676519125699997,
0.07859712839126587,
-0.01914253458380699,
0.014436083845794201,
-0.006679491605609655,
0.059713445603847504,
0.03660545125603676,
0.06337570399045944,
-0.022201325744390488,
-0.011713564395904541,
-0.1158989667892456,
0.03196409344673157,
-0.08833484351634979,
-0.0556679368019104,
-0.09475161880254745,
0.01697968877851963,
-0.10970661044120789,
-0.09349208325147629,
0.0506763830780983,
-0.03784891590476036,
-0.061978232115507126,
0.023644592612981796,
0.025637654587626457,
-0.04960189014673233,
0.049700092524290085,
0.003767888993024826,
-0.06160927563905716,
0.018799953162670135,
0.006558725144714117,
-0.08031418174505234,
0.009634843096137047,
0.04522103816270828,
0.007913642562925816,
0.11829143762588501,
0.0274386964738369,
0.013111155480146408,
-0.08153147250413895,
0.03420228883624077,
0.024559523910284042,
0.07393714785575867,
0.01982073299586773,
-0.04799208790063858,
0.0271163173019886,
-0.00353539502248168,
-0.00014867493882775307,
0.03865355998277664,
0.017958233132958412,
0.014561571180820465,
-0.0005100425914861262,
0.056217677891254425,
0.12629354000091553,
-0.06744595617055893,
0.0585377998650074,
0.05190746858716011,
0.005204933229833841,
0.010546602308750153,
0.058614835143089294,
0.07391034811735153,
0.045484431087970734,
0.02707909606397152,
0.08267244696617126,
-0.062102094292640686,
-0.02644365467131138,
-0.009400313720107079,
0.054768968373537064,
-0.02611587382853031,
-0.04484555497765541,
0.04866255074739456,
0.06387245655059814,
0.027911808341741562,
0.0016866882797330618,
0.009736226871609688,
-0.05337623506784439,
0.07822773605585098,
-0.05040615424513817,
-1.2856467121954785e-33,
0.04773738235235214,
-0.012192967347800732,
-0.021294187754392624,
-0.019745726138353348,
-0.07525116205215454,
-0.05283799022436142,
0.02387816272675991,
-0.06399044394493103,
-0.0038202523719519377,
0.05019982159137726,
0.06775832176208496,
0.018463347107172012,
0.016186410561203957,
-0.05991159379482269,
-0.050420042127370834,
-0.02528960071504116,
0.0454697459936142,
-0.023064246401190758,
0.03422728180885315,
-0.03322968631982803,
0.01122177392244339,
0.04249265044927597,
-0.00413035973906517,
-0.01994866319000721,
-0.008008316159248352,
-0.016854964196681976,
0.013155201449990273,
-0.02389967069029808,
0.0007126498967409134,
0.051193755120038986,
-0.02067309245467186,
0.07409761101007462,
-0.014543223194777966,
-0.08583451807498932,
0.07575724273920059,
0.023264756426215172,
0.01789908856153488,
-0.009539414197206497,
-0.05384710058569908,
0.00200031790882349,
-0.0373244546353817,
-0.04193738102912903,
0.018808456137776375,
-0.005118454806506634,
0.022712482139468193,
0.01611911505460739,
0.03127601370215416,
-0.03341969475150108,
0.02440803125500679,
-0.0485461950302124,
-0.09249767661094666,
-0.050923120230436325,
0.049745529890060425,
0.005551720503717661,
0.018139101564884186,
0.08126402646303177,
0.0007157514919526875,
-0.04615534469485283,
-0.0028287498280406,
0.006938411388546228,
-0.0016952021978795528,
-0.005321325268596411,
0.04652474448084831,
-0.11650338023900986,
-0.025826042518019676,
0.11329741030931473,
0.017619267106056213,
0.010423386469483376,
-0.001592907472513616,
-0.05005433037877083,
-0.019113363698124886,
-0.0077589419670403,
0.06321258842945099,
0.043393492698669434,
0.01638077013194561,
-0.034794874489307404,
0.038771819323301315,
0.05330487713217735,
-0.008628379553556442,
-0.02425185963511467,
0.08738379925489426,
-0.06837733834981918,
0.015123296529054642,
-0.055918291211128235,
-0.04087609425187111,
0.03584032133221626,
0.003528486005961895,
0.004509754478931427,
-0.07034768909215927,
0.05518430098891258,
0.05072417110204697,
0.0713866725564003,
0.03733814135193825,
0.12028110772371292,
-0.007507589180022478,
-2.6968557165218954e-8,
-0.02315206080675125,
0.014899122528731823,
0.03683541715145111,
-0.08168400824069977,
-0.10291580855846405,
-0.06837809085845947,
-0.08373837918043137,
-0.008870192803442478,
0.016281791031360626,
0.0044230567291378975,
-0.04343255236744881,
0.024657169356942177,
0.012480557896196842,
0.08345319330692291,
0.005031298380345106,
-0.06532255560159683,
-0.001529067289084196,
-0.03658830747008324,
-0.01565774716436863,
0.025241192430257797,
-0.08798205852508545,
0.009869646281003952,
0.025301232933998108,
-0.05986635014414787,
-0.03220100328326225,
0.004563264548778534,
-0.0019187743309885263,
-0.018673531711101532,
0.05713338777422905,
0.01680855266749859,
-0.03667128458619118,
0.08860495686531067,
0.057948093861341476,
0.0057418071664869785,
0.03420823812484741,
0.0253737885504961,
-0.009044613689184189,
-0.047002676874399185,
-0.015662575140595436,
-0.03989506512880325,
-0.007307660765945911,
-0.06468270719051361,
0.01813790760934353,
0.026612941175699234,
-0.005925808567553759,
0.02367948181927204,
-0.01663406938314438,
0.045029282569885254,
-0.060778986662626266,
-0.007751200348138809,
-0.057132553309202194,
-0.004458192735910416,
-0.021673528477549553,
-0.05720486491918564,
0.05011213198304176,
-0.028534743934869766,
0.009429126977920532,
0.041230227798223495,
0.013248169794678688,
-0.06274334341287613,
-0.012359578162431717,
-0.09198354929685593,
0.05011480301618576,
0.008869849145412445
] |
PMID:27038494 | Among these analogs, the most potent compound 10a exhibited potent inhibitory activity against MMP-2 with IC50 value of 0.19 nM, which is 5 times more potent than that of Ilomastat (IC50=0.94 nM). | [
-0.04336757957935333,
-0.029861697927117348,
0.018798353150486946,
-0.032458506524562836,
-0.004940441343933344,
-0.007198456209152937,
0.016941968351602554,
0.16510331630706787,
0.03130593150854111,
0.05376654118299484,
0.012411200441420078,
0.0037644102703779936,
-0.05261857062578201,
0.016121413558721542,
-0.06331861764192581,
0.12344884127378464,
0.11542388796806335,
0.08489236980676651,
0.08175010979175568,
0.05108429864048958,
-0.036044467240571976,
-0.06532204896211624,
0.04616296663880348,
-0.015604150481522083,
-0.020260125398635864,
0.13680727779865265,
-0.011775122955441475,
0.03489776700735092,
-0.04390901327133179,
-0.03506546840071678,
-0.008042248897254467,
0.017934152856469154,
-0.0054992265067994595,
-0.07167896628379822,
-0.05301104858517647,
-0.07029105722904205,
-0.0912572592496872,
0.03974316269159317,
-0.03870203346014023,
0.007038946263492107,
0.06295571476221085,
-0.05619390681385994,
0.027473336085677147,
-0.051303375512361526,
0.012037092819809914,
-0.11569420993328094,
-0.12012233585119247,
0.033549051731824875,
-0.03586634621024132,
0.12111404538154602,
-0.031741395592689514,
0.021671073511242867,
-0.06602168083190918,
0.03770878538489342,
-0.008527535945177078,
-0.062152083963155746,
-0.08979777246713638,
0.13098588585853577,
0.029766574501991272,
-0.0018895616522058845,
0.024591052904725075,
0.07154382020235062,
0.00555950915440917,
0.05414620041847229,
-0.006520140916109085,
0.0248271431773901,
-0.042576760053634644,
-0.033815253525972366,
0.0321086123585701,
0.04337072744965553,
0.004617311060428619,
-0.02165529690682888,
-0.03166748955845833,
-0.015329761430621147,
0.019204536452889442,
0.03809790685772896,
0.008175987750291824,
-0.027513330802321434,
0.04988386482000351,
-0.01901445910334587,
0.04295511916279793,
0.05503881722688675,
0.0713777169585228,
-0.0211756844073534,
-0.022475315257906914,
0.0638006329536438,
0.011758502572774887,
0.0711134523153305,
0.006964678410440683,
-0.034285638481378555,
0.05463803559541702,
0.08169932663440704,
-0.04052254185080528,
-0.0077753085643053055,
0.04269985109567642,
0.020175857469439507,
-0.036735571920871735,
0.09290008246898651,
-0.07737434655427933,
0.03765622153878212,
0.060006868094205856,
0.059430208057165146,
-0.17343489825725555,
-0.07544232904911041,
-0.030391154810786247,
-0.013757346197962761,
0.08632762730121613,
-0.09667108952999115,
-0.01833823323249817,
0.01277482695877552,
0.011232603341341019,
-0.005622786935418844,
-0.08548709750175476,
-0.011295321397483349,
0.07188758999109268,
0.03124263323843479,
0.09042252600193024,
0.018911851570010185,
0.04336356744170189,
-0.04850876331329346,
-0.02591327764093876,
-0.14591199159622192,
-0.02766965515911579,
0.00288090156391263,
-0.025657813996076584,
0.07967645674943924,
0.016616659238934517,
2.4317510410178203e-33,
-0.016809388995170593,
-0.000301000865874812,
0.06373635679483414,
0.011105762794613838,
0.009912223555147648,
-0.05539317429065704,
-0.007568816188722849,
-0.06443643569946289,
-0.03099384717643261,
-0.03305927664041519,
-0.06840178370475769,
-0.08506778627634048,
-0.008722366765141487,
0.04464166611433029,
0.023211050778627396,
-0.06691046059131622,
0.061970122158527374,
0.0024459653068333864,
0.06771411001682281,
-0.08701471984386444,
0.06572769582271576,
0.02241193689405918,
-0.056729525327682495,
0.026484206318855286,
0.017172817140817642,
0.062286488711833954,
-0.0521964430809021,
0.10025474429130554,
-0.002309669740498066,
-0.007272039540112019,
-0.028981497511267662,
0.00911200325936079,
-0.05942727252840996,
-0.015689875930547714,
-0.07043098658323288,
-0.03493351489305496,
0.0032655526883900166,
-0.07910463958978653,
0.045091960579156876,
-0.06817089021205902,
-0.0962042286992073,
-0.0000922223916859366,
0.01593617908656597,
-0.03707190230488777,
0.042035363614559174,
-0.05339045077562332,
-0.07493815571069717,
-0.007519313599914312,
0.0003710799210239202,
-0.011315805837512016,
0.006164113059639931,
0.02794773131608963,
-0.02341410331428051,
0.11163698136806488,
-0.011739649809896946,
0.011784729547798634,
-0.041102949529886246,
0.01680390164256096,
0.05498766899108887,
0.09394935518503189,
0.03474043309688568,
-0.055929213762283325,
-0.028285879641771317,
0.037014007568359375,
-0.02424219809472561,
0.10599630326032639,
-0.03393223509192467,
-0.05333710461854935,
-0.020663682371377945,
0.10373206436634064,
0.03385866805911064,
-0.043571531772613525,
0.06102853640913963,
-0.00887531228363514,
0.057072412222623825,
0.015405888669192791,
0.06989717483520508,
0.02951362170279026,
0.01188109815120697,
0.07557997852563858,
0.009136189706623554,
-0.056212324649095535,
-0.057263050228357315,
0.022443575784564018,
-0.031877242028713226,
-0.06387931108474731,
-0.050590917468070984,
-0.048725876957178116,
0.03898566588759422,
0.0224929116666317,
0.0658370777964592,
0.00001691119177849032,
-0.08262419700622559,
0.034731559455394745,
-0.04809887707233429,
-3.983019344387315e-33,
0.044784314930438995,
-0.03337106853723526,
0.04378269240260124,
0.04974778741598129,
-0.11723513156175613,
0.05568131059408188,
0.05225401744246483,
-0.08572538197040558,
0.05722910538315773,
0.017774038016796112,
0.11704082787036896,
0.013847094029188156,
0.01702851802110672,
-0.09293592721223831,
-0.019770972430706024,
-0.021610939875245094,
0.03531176224350929,
0.03630794584751129,
0.053868889808654785,
0.022695887833833694,
0.06447958946228027,
0.06547839194536209,
0.0022578102070838213,
0.013543210923671722,
-0.0012405491434037685,
-0.011229929514229298,
-0.020972035825252533,
-0.02608461119234562,
0.00829229410737753,
0.02906779758632183,
-0.016666363924741745,
0.06215154007077217,
-0.023679116740822792,
-0.07215546071529388,
0.023650066927075386,
-0.020031210035085678,
0.042921461164951324,
-0.03931794315576553,
-0.12409691512584686,
0.0169915072619915,
-0.0076559437438845634,
0.008069003000855446,
-0.034917593002319336,
0.03471849486231804,
0.02493163011968136,
0.013262355700135231,
0.01113620214164257,
0.011768086813390255,
0.04239468276500702,
-0.07156495004892349,
-0.05241599306464195,
-0.023986434563994408,
0.014882748015224934,
0.04693612456321716,
0.013114332221448421,
0.03521479666233063,
-0.006193928886204958,
-0.011655138805508614,
-0.003760726423934102,
0.025372320786118507,
-0.013837026432156563,
0.003159408690407872,
-0.01833278127014637,
-0.08510367572307587,
0.02601400762796402,
0.11489611119031906,
-0.009630913846194744,
0.09390311688184738,
0.025555336847901344,
-0.05721415579319,
0.004730683285742998,
0.004533989820629358,
0.060754287987947464,
0.015056781470775604,
-0.05068795755505562,
-0.026816004887223244,
0.05743324011564255,
-0.046940699219703674,
0.03291194140911102,
-0.05057412013411522,
0.038969580084085464,
0.000993823749013245,
-0.03890019282698631,
-0.08993977308273315,
-0.08478032052516937,
0.027578802779316902,
-0.003463550005108118,
0.017685459926724434,
-0.07771862298250198,
0.04490062594413757,
0.03823845088481903,
0.0014340945053845644,
-0.038967378437519073,
0.05753566324710846,
-0.006173274014145136,
-3.5442887735825934e-8,
-0.0031254428904503584,
0.01584819331765175,
0.08669595420360565,
-0.07949154078960419,
-0.04708045348525047,
-0.007539591286331415,
-0.0682806521654129,
0.04557208716869354,
0.015422657132148743,
0.03884325921535492,
0.004355220589786768,
0.014172363094985485,
-0.0217972993850708,
0.029704438522458076,
0.028421206399798393,
-0.036821842193603516,
0.022045088931918144,
-0.022922201082110405,
-0.020200062543153763,
-0.02404862642288208,
-0.04179363325238228,
0.01976502686738968,
0.00840301625430584,
-0.11641748994588852,
-0.041512906551361084,
-0.02285771816968918,
0.03387165069580078,
0.005796847864985466,
0.03769442439079285,
-0.0061369542963802814,
-0.048005618155002594,
0.010792202316224575,
0.012139493599534035,
0.012769936583936214,
0.02102002687752247,
0.06418409943580627,
-0.014997411519289017,
-0.038301099091768265,
-0.022673867642879486,
-0.019678723067045212,
-0.047072067856788635,
-0.07866853475570679,
0.00895402766764164,
0.011656410060822964,
-0.037117667496204376,
0.00974319502711296,
0.008334924466907978,
0.007794115226715803,
-0.0543951652944088,
-0.08224575221538544,
-0.05782612785696983,
0.05726363882422447,
-0.059974994510412216,
-0.10822424292564392,
-0.016880031675100327,
0.005832542199641466,
-0.03550437092781067,
-0.002487852005288005,
-0.012078458443284035,
-0.08735007792711258,
0.029835287481546402,
-0.08501323312520981,
0.02905968762934208,
-0.017955027520656586
] |
PMID:27038494 | Importantly, 10a exhibited more than 8300 fold selectivity for MMP-2 versus MMP-9 (IC50=1.58 μM). | [
-0.11048433929681778,
-0.02639582008123398,
0.04279434680938721,
0.023726370185613632,
0.013977681286633015,
0.02355111390352249,
0.04442336782813072,
0.16394105553627014,
-0.06438350677490234,
0.06975007802248001,
0.02044626697897911,
-0.04276606813073158,
-0.07114896178245544,
0.05502208322286606,
-0.022399457171559334,
0.07751491665840149,
0.037025533616542816,
0.016075463965535164,
0.02640913799405098,
0.068028025329113,
0.014512971043586731,
-0.08650953322649002,
0.03235718235373497,
-0.06333746761083603,
0.03064737841486931,
0.07395573705434799,
0.025890540331602097,
-0.0035480710212141275,
0.004520622082054615,
-0.007827981375157833,
-0.003176750848069787,
0.02131723240017891,
0.009278450161218643,
-0.042481087148189545,
0.04950661584734917,
-0.034855712205171585,
-0.045058462768793106,
0.001685582217760384,
-0.04807213321328163,
-0.013979921117424965,
0.06360875815153122,
-0.010046412236988544,
0.08263767510652542,
-0.06063314154744148,
-0.010030824691057205,
-0.05917412042617798,
-0.008034735918045044,
0.012646084651350975,
-0.10789558291435242,
0.058345016092061996,
0.011746532283723354,
0.04752355441451073,
-0.055820729583501816,
0.005962332710623741,
0.0007806073990650475,
-0.03934183344244957,
-0.0515371635556221,
0.04585100710391998,
-0.040222760289907455,
0.015712466090917587,
-0.003818834200501442,
0.0376521572470665,
-0.04416147992014885,
0.011785697191953659,
0.07570789009332657,
0.06888621300458908,
0.0010887670796364546,
-0.09692691266536713,
-0.02839495800435543,
-0.010382234118878841,
0.026175914332270622,
-0.009369086474180222,
-0.015247340314090252,
-0.05718950182199478,
0.07268155366182327,
0.01780611462891102,
0.04095980525016785,
-0.03239937126636505,
0.022754458710551262,
0.0657578855752945,
-0.005028238985687494,
0.02872483991086483,
0.011926467530429363,
-0.03822450339794159,
0.0016880285693332553,
-0.03316672518849373,
0.027401141822338104,
0.04379461333155632,
-0.04914802312850952,
-0.09999603033065796,
-0.022978410124778748,
0.022991525009274483,
-0.05033724009990692,
0.022082358598709106,
0.01801237277686596,
0.03649767488241196,
-0.05579593405127525,
0.08053013682365417,
-0.00970500148832798,
-0.014049045741558075,
0.06019105017185211,
0.0722552165389061,
-0.08632691204547882,
0.015543755143880844,
-0.08222034573554993,
-0.02255120873451233,
0.11081074178218842,
-0.01698501594364643,
-0.029044125229120255,
0.023545878008008003,
0.07130007445812225,
0.028928576037287712,
-0.04582925885915756,
-0.03766648471355438,
0.06487352401018143,
-0.006121848244220018,
0.024139869958162308,
0.05387815460562706,
0.08898851275444031,
0.012276549823582172,
-0.09596094489097595,
-0.10383494943380356,
0.006738238502293825,
0.019071480259299278,
0.0015636845491826534,
0.1153615415096283,
-0.007217648904770613,
1.7879195607610067e-33,
-0.00916510820388794,
-0.01421895157545805,
0.0485975481569767,
-0.032829660922288895,
-0.024254344403743744,
-0.09475847333669662,
-0.08119668811559677,
-0.06416662037372589,
-0.020487051457166672,
-0.008584309369325638,
-0.01704067923128605,
-0.028454480692744255,
0.004646914545446634,
0.012719456106424332,
-0.009562942199409008,
-0.05588699132204056,
0.0009811758063733578,
0.07813848555088043,
0.035585202276706696,
-0.06845378875732422,
-0.04314655438065529,
0.033296674489974976,
0.010508994571864605,
0.03619516268372536,
0.06594869494438171,
0.04707343131303787,
-0.041601285338401794,
0.05335028097033501,
-0.012731284834444523,
-0.020957686007022858,
-0.0158687736839056,
0.0009541866020299494,
-0.08402407169342041,
-0.05766218900680542,
-0.04714248701930046,
0.10121504217386246,
-0.07263117283582687,
-0.010198846459388733,
0.030591046437621117,
-0.025772569701075554,
-0.04551259055733681,
0.01593470759689808,
0.0776449665427208,
0.005698708817362785,
0.030406992882490158,
-0.09264051169157028,
-0.07745897769927979,
-0.06636657565832138,
-0.01886289194226265,
-0.03541751205921173,
-0.0028155259788036346,
0.01165539026260376,
-0.04055819660425186,
0.10959271341562271,
0.09011255949735641,
-0.0012833243235945702,
0.07932180166244507,
0.05302029848098755,
0.06315840780735016,
0.1044473797082901,
0.04678506404161453,
-0.01563282310962677,
-0.014181154780089855,
0.00024809406022541225,
0.0272390004247427,
0.10276882350444794,
-0.002610676223412156,
0.007308564148843288,
0.04158161208033562,
0.0399739034473896,
0.011893730610609055,
-0.007420002017170191,
0.058372266590595245,
-0.01835380680859089,
0.07173176109790802,
0.029425648972392082,
0.10455630719661713,
-0.00042759167263284326,
0.10394919663667679,
0.014968941919505596,
0.021476903930306435,
-0.0069176503457129,
-0.06913084536790848,
-0.09887531399726868,
-0.09004256129264832,
-0.031081829220056534,
-0.044950760900974274,
-0.05204828456044197,
0.023140378296375275,
-0.004816476721316576,
0.06894612312316895,
0.03582804650068283,
-0.004806074779480696,
-0.038238774985075,
-0.08835361897945404,
-2.1010146851544307e-33,
0.014592491090297699,
-0.04996033012866974,
-0.01414640061557293,
0.04755605384707451,
-0.10034901648759842,
-0.014459787867963314,
0.0686110258102417,
-0.051089175045490265,
0.003537515178322792,
0.011742428876459599,
0.11564239859580994,
0.0408337339758873,
0.04807179793715477,
-0.10358801484107971,
-0.019523197785019875,
0.025831948965787888,
0.02336321957409382,
0.028460843488574028,
0.12319932132959366,
0.012891200371086597,
0.13183754682540894,
0.08137950301170349,
0.01108497753739357,
0.0020683591719716787,
-0.05363111197948456,
-0.007100356742739677,
-0.020522527396678925,
-0.03266289457678795,
0.08916305005550385,
-0.028146738186478615,
-0.03081584721803665,
0.00948119442909956,
-0.039916202425956726,
0.014106029644608498,
0.0179572906345129,
-0.07696198672056198,
-0.022608092054724693,
-0.0059843058697879314,
-0.09002479165792465,
0.051901742815971375,
-0.026196148246526718,
0.04229031875729561,
-0.03221429884433746,
0.00685295183211565,
-0.03245904669165611,
0.04167881980538368,
0.023545706644654274,
-0.0175790898501873,
0.013871549628674984,
-0.05560256913304329,
-0.03617275878787041,
-0.05003729462623596,
-0.007660612463951111,
0.03334223851561546,
-0.058924343436956406,
0.05600348114967346,
0.023030422627925873,
0.05245804041624069,
-0.006675090175122023,
0.035977717489004135,
0.022239921614527702,
0.04207191616296768,
-0.0015533332480117679,
-0.07959911227226257,
-0.0224925484508276,
0.09837833791971207,
0.07274746149778366,
0.024640250951051712,
-0.04411580041050911,
-0.03773828223347664,
-0.017517058178782463,
-0.04045180231332779,
0.12180270999670029,
-0.016809364780783653,
0.002976365387439728,
-0.02546875737607479,
0.044758204370737076,
0.06707248091697693,
0.09405998140573502,
-0.023026635870337486,
0.009717714972794056,
-0.03664213418960571,
-0.09020622819662094,
-0.019513383507728577,
0.001572340028360486,
-0.020447006449103355,
-0.0156191261485219,
-0.04421553015708923,
0.03182269632816315,
0.02642212249338627,
0.05059882998466492,
-0.008480554446578026,
0.049604855477809906,
-0.01094441395252943,
0.004274553153663874,
-2.9510713872582528e-8,
0.032547544687986374,
-0.03716043755412102,
0.05475546419620514,
-0.04765891656279564,
-0.00819873996078968,
-0.053807612508535385,
-0.0312068872153759,
0.022467734292149544,
0.017193106934428215,
0.03897002339363098,
0.06377182900905609,
-0.05859481543302536,
-0.10846374183893204,
0.039414435625076294,
0.12263299524784088,
-0.09199133515357971,
-0.033653222024440765,
0.008363405242562294,
-0.014584008604288101,
-0.018399406224489212,
-0.058223988860845566,
0.010577978566288948,
0.12087462842464447,
-0.09338682144880295,
-0.05783696472644806,
0.06509148329496384,
-0.07779842615127563,
0.018694613128900528,
0.014496215619146824,
0.014021762646734715,
-0.018009411171078682,
0.04371161013841629,
-0.01479865051805973,
-0.03317490592598915,
0.006877964828163385,
0.03191003203392029,
0.021716130897402763,
-0.011117121204733849,
-0.014311169274151325,
0.051963984966278076,
0.0005413545877672732,
-0.08062227815389633,
-0.030685171484947205,
0.017062734812498093,
-0.06199313700199127,
0.04677221179008484,
-0.006866226438432932,
0.00986005924642086,
-0.0950048640370369,
-0.016011323779821396,
-0.03942875936627388,
-0.018009193241596222,
-0.05821213871240616,
-0.08914569765329361,
-0.12561333179473877,
-0.0124404551461339,
-0.031656354665756226,
0.018621033057570457,
-0.022133443504571915,
-0.02288857102394104,
0.031066739931702614,
-0.08979048579931259,
-0.08481143414974213,
-0.00490229669958353
] |
PMID:27038494 | Molecular docking studies showed that 10a bond to the catalytic active pocket of MMP-2 by a non-zinc-chelating mechanism which was different from that of Ilomastat. | [
-0.10459475964307785,
0.009216822683811188,
-0.0063421353697776794,
-0.010477089323103428,
0.06732409447431564,
-0.054432135075330734,
0.022930514067411423,
0.11414314806461334,
0.04428285360336304,
0.03446666896343231,
0.014042525552213192,
0.014243349432945251,
-0.052840281277894974,
-0.01600050739943981,
-0.03739677742123604,
0.0855465829372406,
0.023290522396564484,
0.0441245511174202,
0.08555197715759277,
0.06607101112604141,
-0.009071404114365578,
-0.10777417570352554,
0.05794248729944229,
-0.12750042974948883,
0.033206477761268616,
0.11693869531154633,
0.06993216276168823,
-0.007699036505073309,
-0.02976091019809246,
-0.00019461223564576358,
-0.02875213883817196,
-0.006735377945005894,
-0.007999191991984844,
-0.03525871783494949,
0.05876773223280907,
-0.02151045948266983,
-0.06444098800420761,
0.03159784898161888,
-0.061715878546237946,
-0.03846977278590202,
0.07911427319049835,
0.03899187967181206,
0.036486949771642685,
-0.09609577059745789,
0.00606427202001214,
-0.0663255900144577,
-0.07130139321088791,
0.0010255397064611316,
-0.08438793569803238,
0.07801990211009979,
-0.05697501823306084,
0.037124473601579666,
-0.052061423659324646,
-0.031308844685554504,
-0.02593458630144596,
-0.025356648489832878,
-0.07498741149902344,
0.1348767876625061,
-0.012618869543075562,
-0.0210020300000906,
0.09908690303564072,
-0.0011214525438845158,
-0.04247543215751648,
0.02793128788471222,
0.041294172406196594,
0.02023237943649292,
-0.01696615479886532,
-0.017840294167399406,
0.0006226664991118014,
0.01808295026421547,
-0.029930705204606056,
-0.008501969277858734,
-0.034323129802942276,
-0.07616428285837173,
0.031100338324904442,
0.026631345972418785,
0.005360533017665148,
-0.04080208018422127,
0.051580410450696945,
0.039309997111558914,
0.0036355366464704275,
0.09788454324007034,
0.10281624644994736,
0.008265630342066288,
-0.005924778524786234,
0.06510715186595917,
-0.020736485719680786,
0.08795727044343948,
-0.05345337837934494,
-0.028091877698898315,
0.027095599099993706,
0.07777155935764313,
-0.029702523723244667,
0.04251761734485626,
-0.025558216497302055,
0.02816847525537014,
0.055705808103084564,
0.11505386978387833,
-0.000418364186771214,
0.00401603477075696,
0.04176046699285507,
0.12154219299554825,
-0.09837108105421066,
-0.10669500380754471,
-0.03198770061135292,
0.008152038790285587,
0.026600319892168045,
-0.025365466251969337,
0.019982516765594482,
0.007419348694384098,
0.04751535877585411,
-0.011642441153526306,
0.005086573772132397,
-0.028756286948919296,
0.014044816605746746,
0.07936752587556839,
0.009843524545431137,
-0.027129890397191048,
0.0251722764223814,
-0.018763074651360512,
-0.025373276323080063,
-0.05998456850647926,
-0.028819778934121132,
-0.020812779664993286,
-0.04919978603720665,
0.07811330258846283,
-0.042185407131910324,
-2.1571663972542806e-33,
-0.043202683329582214,
0.0005887362058274448,
0.07500122487545013,
0.01674661599099636,
-0.02308991551399231,
-0.028453266248106956,
-0.025509677827358246,
-0.09674204885959625,
-0.09557457268238068,
0.0030263469088822603,
-0.027187000960111618,
-0.12508083879947662,
0.054119132459163666,
-0.043038371950387955,
-0.04763651266694069,
-0.07312928140163422,
0.06797318905591965,
0.020188380032777786,
0.07200901955366135,
-0.04853706434369087,
0.03649693354964256,
0.06004577502608299,
-0.01967748813331127,
-0.018457138910889626,
0.055640678852796555,
0.0666668638586998,
-0.0008920262334868312,
0.009978982619941235,
0.013174274004995823,
-0.005277044605463743,
-0.041912905871868134,
0.036549538373947144,
-0.12099365890026093,
0.014904133975505829,
0.008371485397219658,
-0.0007090591825544834,
-0.03710146248340607,
-0.05704015493392944,
0.024751141667366028,
-0.09315628558397293,
-0.03728436306118965,
-0.009015355259180069,
0.026902910321950912,
0.025159694254398346,
-0.00481224013492465,
-0.07337731868028641,
-0.00889115035533905,
0.002581484615802765,
0.031984396278858185,
-0.04596184194087982,
0.008285227231681347,
0.013350820168852806,
-0.007092070300132036,
0.08632082492113113,
-0.045833930373191833,
0.025383539497852325,
-0.025007840245962143,
0.011105811223387718,
0.014152070507407188,
0.0771382674574852,
-0.005358296912163496,
-0.04065115004777908,
-0.015657206997275352,
0.045673247426748276,
0.000027894659069716,
0.10185741633176804,
-0.05487009510397911,
0.011795266531407833,
0.005084649659693241,
0.16540712118148804,
0.05226544290781021,
0.0007021558121778071,
0.1131705567240715,
0.03018808364868164,
0.058270376175642014,
0.02835303731262684,
0.05250241607427597,
0.026033932343125343,
0.03623916581273079,
0.0521882101893425,
0.019702965393662453,
-0.06475098431110382,
-0.03339967131614685,
-0.02809755504131317,
-0.04385552182793617,
-0.10684982687234879,
-0.09319423139095306,
-0.006729362066835165,
0.06264762580394745,
0.07961522042751312,
0.044134996831417084,
-0.0366930291056633,
-0.11089447140693665,
0.026883406564593315,
-0.048381198197603226,
-7.54829233289887e-34,
0.06677526980638504,
-0.03904293105006218,
-0.002265911316499114,
-0.06674116104841232,
-0.12485156208276749,
0.0040588462725281715,
-0.002712828805670142,
-0.1268189698457718,
-0.0054267155937850475,
0.040932685136795044,
0.12596403062343597,
0.025201179087162018,
0.07358872890472412,
-0.013499315828084946,
-0.021928977221250534,
-0.00690262857824564,
0.033485013991594315,
0.05439088121056557,
0.11434963345527649,
0.003759054932743311,
0.09372889250516891,
-0.013707977719604969,
0.01387596596032381,
0.03438027203083038,
-0.030913688242435455,
-0.014559897594153881,
0.035715971142053604,
-0.06240290030837059,
0.049058012664318085,
0.07463777810335159,
0.02777111902832985,
0.08413425087928772,
-0.06398218870162964,
-0.057404857128858566,
0.013284619897603989,
-0.01380841713398695,
-0.006489400751888752,
-0.007724106777459383,
-0.06475002318620682,
0.01011055987328291,
-0.029298704117536545,
-0.03601614758372307,
-0.02728402055799961,
0.03562651202082634,
0.06135997176170349,
-0.01847907342016697,
0.016453510150313377,
0.010356247425079346,
-0.021147925406694412,
-0.0887322649359703,
-0.02885102853178978,
-0.007337148301303387,
0.0076095531694591045,
-0.02456771582365036,
0.005734207108616829,
0.0901552140712738,
-0.0016695279628038406,
-0.024385368451476097,
0.013481033965945244,
-0.02598540298640728,
0.03886513039469719,
-0.03986821696162224,
0.02116786316037178,
-0.08696865290403366,
-0.000552477256860584,
0.06711835414171219,
-0.007345542777329683,
0.029062628746032715,
-0.0012313007609918714,
-0.02127227373421192,
-0.0059408643282949924,
0.02342924103140831,
0.017938952893018723,
0.02007090300321579,
0.005867969710379839,
0.018998082727193832,
0.05405214801430702,
-0.039694759994745255,
0.07718508690595627,
-0.06913425028324127,
0.03941623866558075,
-0.005856925621628761,
0.0720904991030693,
-0.07573620975017548,
-0.04216492548584938,
-0.037666115909814835,
0.008234167471528053,
0.06022154539823532,
-0.09175466746091843,
0.013363305479288101,
0.009465628303587437,
-0.029459305107593536,
-0.03129381313920021,
0.10093087702989578,
-0.023716997355222702,
-2.742012661371973e-8,
-0.07495707273483276,
0.0074740988202393055,
0.07408139854669571,
-0.06147455796599388,
-0.09366995841264725,
0.004320330452173948,
-0.06140327453613281,
0.0050369431264698505,
0.03845610097050667,
0.023070041090250015,
-0.03126470372080803,
-0.021928729489445686,
-0.02926313690841198,
-0.011729467660188675,
0.05789417028427124,
-0.017944853752851486,
0.013465591706335545,
-0.09344540536403656,
-0.040510132908821106,
-0.0008908541058190167,
-0.03504658862948418,
0.01499571930617094,
-0.018558982759714127,
-0.034712910652160645,
-0.035476334393024445,
-0.060963116586208344,
0.02054431661963463,
0.04801847040653229,
0.03223949298262596,
-0.03659592568874359,
-0.04842890799045563,
0.000595282472204417,
-0.018453441560268402,
-0.001417317776940763,
-0.0010837510926648974,
-0.02766975201666355,
-0.013286297209560871,
-0.13326537609100342,
0.019994815811514854,
-0.03065524250268936,
-0.022493036463856697,
-0.04185754805803299,
0.012393705546855927,
0.013891911134123802,
-0.10493924468755722,
0.04858335480093956,
0.02366829849779606,
0.006551499478518963,
-0.04546590521931648,
-0.013816590420901775,
-0.02624434418976307,
-0.03288393095135689,
-0.03151232749223709,
-0.08387157320976257,
0.001927569624967873,
0.02614525519311428,
-0.0167332012206316,
0.058459579944610596,
0.05724342167377472,
-0.07131172716617584,
0.007272929418832064,
-0.013579624705016613,
0.05129183828830719,
-0.022750873118638992
] |
PMID:27038494 | Furthermore, the invasion assay showed that 10a was effective in reducing HEY cells invasion at 84.6% in 50 μM concentration. | [
-0.03627607226371765,
0.07304515689611435,
0.003380783833563328,
-0.08026235550642014,
0.0385153591632843,
-0.01404112484306097,
0.05221908912062645,
0.11101481318473816,
-0.037180520594120026,
0.06646732240915298,
0.05930555611848831,
0.02747253142297268,
-0.024941276758909225,
0.0989551991224289,
0.001981752924621105,
0.06159204989671707,
0.04229670390486717,
0.044263217598199844,
-0.11788206547498703,
-0.008247042074799538,
0.013077742420136929,
0.012292154133319855,
0.10490718483924866,
-0.04906387999653816,
-0.02653021737933159,
-0.07378694415092468,
0.0028268119785934687,
0.045904774218797684,
-0.02570926398038864,
-0.01961028017103672,
-0.002660500817000866,
0.06636835634708405,
0.03560321778059006,
-0.007148178294301033,
-0.036726173013448715,
-0.03939635679125786,
-0.0072890412993729115,
-0.05323126167058945,
-0.02757536992430687,
0.0382423996925354,
0.0764026939868927,
-0.014619182795286179,
0.03192866966128349,
-0.017976954579353333,
-0.010968171060085297,
-0.06693535298109055,
-0.05732114985585213,
-0.010585593059659004,
0.04256802052259445,
0.04733319208025932,
-0.00024357414804399014,
-0.015127346850931644,
-0.056136973202228546,
0.034905046224594116,
-0.021434292197227478,
0.01725192554295063,
-0.0737699642777443,
0.0024336385540664196,
0.061793792992830276,
-0.013487461023032665,
-0.06789837032556534,
0.014714660122990608,
0.04262915998697281,
-0.0041677216067910194,
-0.023485299199819565,
-0.03646310046315193,
-0.004201589617878199,
-0.01644989103078842,
-0.07119222730398178,
0.019124913960695267,
0.06367211043834686,
-0.06319291889667511,
-0.0363977774977684,
-0.07981569319963455,
-0.03811151906847954,
0.028403757140040398,
-0.008316727355122566,
0.007359582930803299,
0.034925173968076706,
-0.025580141693353653,
0.05975218862295151,
0.0002430718595860526,
0.053739193826913834,
0.0234061349183321,
-0.04545361548662186,
0.01791476272046566,
0.06657592207193375,
-0.016436701640486717,
-0.02833469770848751,
0.03278527408838272,
0.020507393404841423,
0.0019395546987652779,
0.020540433004498482,
0.006413415540009737,
-0.03817126899957657,
0.02259758487343788,
-0.006319196429103613,
0.05158738046884537,
-0.0657416507601738,
-0.006680770311504602,
0.04421519860625267,
-0.00884636677801609,
-0.0674690306186676,
-0.05696868523955345,
-0.020766261965036392,
-0.0021897947881370783,
0.09876188635826111,
0.030207710340619087,
-0.014231895096600056,
0.008042333647608757,
0.08063003420829773,
-0.018731802701950073,
-0.00426494562998414,
0.03588365390896797,
0.05432911217212677,
-0.00437534786760807,
0.08457519859075546,
-0.05224117264151573,
-0.04349043220281601,
-0.04090051352977753,
0.009133048355579376,
-0.13217030465602875,
0.057270072400569916,
-0.02587752975523472,
0.02113948203623295,
0.05679567903280258,
-0.04840493202209473,
-2.6272211497156776e-34,
0.03169616311788559,
-0.023762278258800507,
-0.02915416657924652,
0.018793027848005295,
-0.027955763041973114,
-0.05633826181292534,
-0.03717561438679695,
-0.0025465749204158783,
-0.018332401290535927,
-0.08084046095609665,
-0.10804754495620728,
-0.013867312110960484,
-0.0015181502094492316,
-0.006748907268047333,
-0.06861931830644608,
0.0017609200440347195,
-0.024911176413297653,
0.041109517216682434,
-0.03054817020893097,
-0.03805083781480789,
-0.07915888726711273,
-0.02866264060139656,
-0.015621556900441647,
0.02615184336900711,
0.021434985101222992,
0.043994270265102386,
-0.12926575541496277,
0.01564333401620388,
0.062022630125284195,
-0.026316745206713676,
0.07518596947193146,
-0.04301358759403229,
-0.034045882523059845,
0.02496357262134552,
0.0012265566037967801,
0.05347582325339317,
0.059725694358348846,
0.006618816405534744,
0.01927284151315689,
-0.040806226432323456,
-0.05321168527007103,
0.061581019312143326,
0.01575121469795704,
-0.06586254388093948,
0.09619808942079544,
-0.03717712685465813,
-0.09289262443780899,
0.009116968140006065,
0.06323407590389252,
-0.019972052425146103,
-0.01694319397211075,
0.02682940475642681,
0.034489937126636505,
0.022934570908546448,
-0.04884013533592224,
-0.009639205411076546,
0.010212118737399578,
0.05267222225666046,
0.011780214495956898,
0.0719008669257164,
0.04749244451522827,
-0.02116513065993786,
-0.019541746005415916,
0.11845070123672485,
0.003162508364766836,
0.039908383041620255,
-0.05009612441062927,
-0.011885987594723701,
0.002647467190399766,
0.028249040246009827,
0.01767907664179802,
-0.03609712794423103,
-0.0013370063388720155,
-0.018830539658665657,
0.03561294078826904,
0.006171135231852531,
0.14401154220104218,
0.07069334387779236,
0.02946971170604229,
-0.032438378781080246,
0.10453101992607117,
-0.0050242929719388485,
-0.04642016068100929,
0.023976856842637062,
-0.056345369666814804,
-0.001796316122636199,
-0.07478467375040054,
-0.054360322654247284,
-0.03585648164153099,
0.02363329939544201,
0.0798991322517395,
-0.03973149135708809,
-0.047593049705028534,
-0.07372388988733292,
-0.07119002938270569,
-5.8643245844814595e-34,
0.0766708105802536,
-0.003810123773291707,
-0.03228163719177246,
-0.03469385206699371,
-0.005481937900185585,
0.14562126994132996,
0.08047891408205032,
0.06676094233989716,
0.010532939806580544,
-0.02008315548300743,
0.08323153853416443,
0.0578535795211792,
0.031110180541872978,
-0.11136886477470398,
-0.034424517303705215,
-0.08114627748727798,
0.028692832216620445,
0.03865141049027443,
-0.06270625442266464,
0.017291877418756485,
-0.01037151925265789,
0.04566285386681557,
0.07188932597637177,
-0.04646895080804825,
0.026219185441732407,
0.04974837973713875,
-0.0718969777226448,
0.07563325017690659,
0.04797078296542168,
-0.03161529079079628,
-0.049521785229444504,
-0.004258546978235245,
-0.08555163443088531,
0.02910192683339119,
-0.012041513808071613,
-0.03145727887749672,
0.13385920226573944,
-0.049405261874198914,
-0.02259523794054985,
-0.06177200749516487,
-0.01761488802731037,
-0.06529655307531357,
-0.03602539747953415,
0.03466799110174179,
-0.01080950628966093,
0.11993296444416046,
0.005216754041612148,
0.028509391471743584,
-0.07987228035926819,
-0.004635698162019253,
0.03016681596636772,
0.005455727688968182,
-0.029578331857919693,
0.02301536686718464,
-0.0486302487552166,
0.04444993659853935,
0.09256771206855774,
-0.017006615176796913,
-0.029553577303886414,
-0.03522483631968498,
-0.030848247930407524,
0.025519907474517822,
-0.014880024828016758,
-0.0433688685297966,
-0.055103614926338196,
0.07936999946832657,
0.029240703210234642,
0.17180030047893524,
0.011857794597744942,
-0.08670768141746521,
0.005696225445717573,
0.08425477892160416,
0.024668902158737183,
-0.040548209100961685,
-0.09188524633646011,
0.007388153579086065,
-0.013229995034635067,
-0.12375455349683762,
0.09695781767368317,
0.0019869597163051367,
-0.07838400453329086,
-0.0367097407579422,
-0.06682021170854568,
-0.08608149737119675,
0.09923288226127625,
-0.024366313591599464,
-0.004571849945932627,
0.021593820303678513,
0.01407840009778738,
0.0503196194767952,
0.01814374513924122,
-0.10506737977266312,
-0.036473438143730164,
0.0444510318338871,
-0.018646858632564545,
-2.496880391333889e-8,
0.052912432700395584,
-0.047719914466142654,
0.0574401430785656,
-0.024677913635969162,
0.014588047750294209,
-0.031207598745822906,
-0.018493976444005966,
0.1194317489862442,
0.02890944294631481,
0.027729084715247154,
-0.0009036484989337623,
0.06063220277428627,
-0.06779186427593231,
0.017469095066189766,
0.030854741111397743,
-0.0908193588256836,
0.004893145523965359,
-0.03833019733428955,
-0.057307880371809006,
-0.04361788555979729,
-0.08364766091108322,
0.04850658029317856,
0.011823387816548347,
0.04229264706373215,
0.01092749647796154,
0.016648756340146065,
-0.036619871854782104,
-0.00462490227073431,
0.007059638388454914,
-0.07586183398962021,
0.017003262415528297,
-0.007297865115106106,
-0.05618349835276604,
-0.0019066928653046489,
-0.028394876047968864,
0.06187586113810539,
0.0716002956032753,
-0.015002810396254063,
0.07349314540624619,
0.012748589739203453,
-0.050666917115449905,
-0.05456859990954399,
-0.021513236686587334,
0.027700915932655334,
-0.035420406609773636,
-0.023332180455327034,
-0.01789024844765663,
-0.03509492054581642,
-0.04092034697532654,
-0.07118786871433258,
0.05471840500831604,
0.018705181777477264,
-0.06554856896400452,
-0.055879272520542145,
-0.15791738033294678,
-0.0012477516429498792,
0.050532590597867966,
-0.05241021886467934,
0.027788938954472542,
0.05518122762441635,
0.0536799281835556,
0.04664412885904312,
0.04765181988477707,
-0.002386532723903656
] |
PMID:27038494 | For 10a, the pharmacokinetic properties had been improved and especially the more desirable t1/2z was achieved compared with these of the lead compound Ilomastat. | [
-0.0730729028582573,
-0.01732739806175232,
-0.03401118889451027,
-0.04858071357011795,
-0.02605382166802883,
-0.00867055170238018,
0.027197271585464478,
0.24987460672855377,
-0.0004997284850105643,
0.040830012410879135,
-0.013977139256894588,
0.0360066294670105,
-0.02923334203660488,
0.020006293430924416,
-0.008833157829940319,
-0.024384988471865654,
0.11426671594381332,
0.024527734145522118,
0.02314838208258152,
-0.04165686294436455,
-0.053590357303619385,
0.0065009985119104385,
0.07600696384906769,
0.00009267206769436598,
-0.04838573932647705,
0.02145029418170452,
-0.020666969940066338,
0.025549674406647682,
-0.02498449757695198,
-0.02355092391371727,
-0.033844396471977234,
-0.03344731032848358,
0.0440293624997139,
-0.04951486364006996,
-0.13171128928661346,
-0.0558675117790699,
-0.05942869186401367,
-0.021766288205981255,
-0.06646870076656342,
0.05915199592709541,
0.12013538926839828,
0.004217249806970358,
0.025692354887723923,
-0.013231046497821808,
0.012647532857954502,
-0.0848112478852272,
-0.03314371407032013,
-0.029390864074230194,
-0.020755227655172348,
0.16572028398513794,
-0.035958416759967804,
-0.013542606495320797,
-0.051316339522600174,
0.011913804337382317,
-0.028747040778398514,
-0.015707768499851227,
-0.09653834998607635,
0.1253713220357895,
-0.019533008337020874,
0.008719095960259438,
0.004679889418184757,
0.04399222880601883,
0.02491259016096592,
0.03216817229986191,
0.015458505600690842,
0.045480646193027496,
-0.01574116386473179,
-0.09779420495033264,
-0.008259247057139874,
-0.005447455681860447,
-0.013536760583519936,
0.013832096010446548,
-0.03216129168868065,
-0.04921189323067665,
-0.093653105199337,
0.01766848936676979,
-0.01194760948419571,
-0.06435185670852661,
-0.031092433258891106,
0.039133377373218536,
0.02249448001384735,
0.04454764351248741,
0.02336880937218666,
0.05360923707485199,
-0.035130180418491364,
0.09076981991529465,
-0.01257199328392744,
0.08161929994821548,
-0.027220971882343292,
0.09405382722616196,
0.14079970121383667,
0.11904890090227127,
-0.006899995729327202,
0.008158144541084766,
0.0021185625810176134,
0.034934382885694504,
-0.021474631503224373,
0.02600776217877865,
0.0020299081224948168,
0.0072318632155656815,
0.04478172957897186,
0.031942784786224365,
-0.05504891648888588,
-0.009779457002878189,
-0.022096702829003334,
0.009860650636255741,
0.0844971314072609,
-0.14617229998111725,
-0.04908042401075363,
0.029288049787282944,
-0.023030532523989677,
-0.021067272871732712,
-0.04689624533057213,
-0.02766645886003971,
0.05312831699848175,
0.02620246447622776,
0.01962689869105816,
0.03885596618056297,
0.06420749425888062,
-0.06994086503982544,
0.03778359666466713,
-0.1075403094291687,
0.012645511887967587,
-0.051448527723550797,
0.04652036353945732,
0.009559583850204945,
0.025282379239797592,
8.119559169346982e-34,
-0.022472426295280457,
0.03964383155107498,
0.03759272024035454,
0.0587373748421669,
-0.026270419359207153,
0.042376551777124405,
-0.019563129171729088,
0.0034050848335027695,
-0.03331052511930466,
0.020385360345244408,
-0.1034572422504425,
-0.03578195720911026,
-0.009329070337116718,
0.041737690567970276,
-0.03960563987493515,
-0.05547742545604706,
0.06523503363132477,
0.018901685252785683,
0.026494361460208893,
-0.07049593329429626,
0.05334277078509331,
0.04571953043341637,
-0.05842486023902893,
0.018346883356571198,
0.01348946988582611,
0.048859693109989166,
-0.01254486758261919,
0.04413672536611557,
-0.0376608781516552,
-0.003065544879063964,
-0.04113598167896271,
0.01372510101646185,
-0.10971445590257645,
-0.004772869870066643,
-0.025660254061222076,
-0.03035387396812439,
0.001529479632154107,
0.00019309244817122817,
0.08187923580408096,
-0.055289916694164276,
0.0030355509370565414,
0.03775380924344063,
-0.027913318946957588,
0.009693874977529049,
0.05821472406387329,
-0.014383316971361637,
-0.09584692865610123,
0.037630897015333176,
0.016230616718530655,
-0.025544781237840652,
-0.032286010682582855,
0.011692842468619347,
0.020963191986083984,
0.060846854001283646,
-0.05262133851647377,
0.046271923929452896,
-0.01816950924694538,
0.06371985375881195,
0.04520169273018837,
0.07123519480228424,
0.05786796286702156,
0.018504127860069275,
0.006305604241788387,
0.054836563766002655,
-0.030982423573732376,
0.07899750024080276,
-0.06119376793503761,
-0.06998062133789062,
-0.026487203314900398,
0.029714791104197502,
0.051798686385154724,
-0.06762387603521347,
-0.013796709477901459,
0.007445140741765499,
0.10563778877258301,
0.05355558916926384,
0.0700049176812172,
0.019660428166389465,
0.05545809864997864,
-0.03464026004076004,
-0.04442887008190155,
-0.07458442449569702,
-0.03917950764298439,
0.039637427777051926,
-0.038945626467466354,
-0.018061399459838867,
-0.044155340641736984,
-0.040659349411726,
0.0479908362030983,
0.04789465293288231,
0.0339752733707428,
-0.02895325794816017,
-0.11876188218593597,
0.026512429118156433,
-0.02554301917552948,
-2.3033892619599343e-33,
-0.0034525408409535885,
-0.011135896667838097,
-0.009202682413160801,
0.019627757370471954,
-0.02494610659778118,
0.061380982398986816,
0.02101694792509079,
-0.06085949391126633,
0.10288102179765701,
0.06821859627962112,
0.16839151084423065,
0.06373866647481918,
-0.017565837129950523,
-0.0937291756272316,
-0.001392632839269936,
-0.014242147095501423,
0.005325814709067345,
0.022360146045684814,
-0.008909101597964764,
-0.019197052344679832,
0.0173525158315897,
0.007791082374751568,
-0.03693306818604469,
-0.012572985142469406,
-0.009562715888023376,
0.005311713088303804,
-0.007559160701930523,
-0.008930280804634094,
0.001087286858819425,
0.04310888051986694,
-0.06307902187108994,
-0.011695205233991146,
-0.057569511234760284,
-0.01070812065154314,
-0.06180860474705696,
0.0051345559768378735,
0.05920635536313057,
-0.0586751326918602,
-0.10997683554887772,
0.022281229496002197,
-0.010539948008954525,
-0.05440252274274826,
0.08422234654426575,
0.0011999260168522596,
-0.00634890329092741,
0.03776415437459946,
-0.022220460698008537,
-0.035527702420949936,
0.008677988313138485,
0.001187682501040399,
0.038390278816223145,
0.055174387991428375,
0.03768009692430496,
0.0317658893764019,
0.03597265109419823,
0.03937242925167084,
0.03215029090642929,
-0.04491473361849785,
-0.045523010194301605,
-0.012517220340669155,
0.03189308941364288,
0.07721099257469177,
-0.019272053614258766,
-0.059875525534152985,
0.016532501205801964,
-0.03498227894306183,
0.0011003634426742792,
0.05974264442920685,
0.04118690639734268,
-0.06738144159317017,
0.07569647580385208,
0.023358583450317383,
0.08005408197641373,
-0.04328563064336777,
-0.052502166479825974,
-0.036356598138809204,
0.008183455094695091,
-0.1023939996957779,
0.01698162406682968,
-0.044701460748910904,
0.024011734873056412,
0.006876248866319656,
-0.032972756773233414,
-0.05807840824127197,
-0.049276407808065414,
0.02983037196099758,
0.07146955281496048,
0.005092655774205923,
-0.07324688881635666,
0.03641475737094879,
-0.0004542784590739757,
0.013634912669658661,
-0.05266541615128517,
0.12217271327972412,
-0.04378718137741089,
-3.138125492796462e-8,
-0.06233898922801018,
-0.010460549034178257,
0.0565214529633522,
0.006435834337025881,
-0.07652260363101959,
-0.03585955873131752,
-0.032789263874292374,
0.08726641535758972,
0.021768981590867043,
0.05507061257958412,
-0.03649131953716278,
0.013900703750550747,
0.030026176944375038,
0.05002136528491974,
-0.015519965440034866,
-0.06354129314422607,
-0.018284574151039124,
-0.06589023768901825,
-0.010941018350422382,
-0.034115150570869446,
-0.04625818505883217,
-0.024854429066181183,
0.03925488516688347,
-0.13588130474090576,
-0.016804581508040428,
-0.011540831066668034,
-0.01329165417701006,
0.02540699392557144,
0.04166529327630997,
-0.010862523689866066,
-0.016947563737630844,
-0.0004947283305227757,
0.04776763543486595,
0.014421358704566956,
0.029146239161491394,
0.04498711973428726,
-0.012788212858140469,
-0.016097351908683777,
0.0071660843677818775,
-0.028037702664732933,
-0.05690672993659973,
-0.09433260560035706,
-0.004566860385239124,
0.06641709059476852,
-0.09496132284402847,
-0.06424706429243088,
0.008982589468359947,
0.038534071296453476,
-0.027989566326141357,
-0.0897732600569725,
-0.022246070206165314,
0.11184585094451904,
-0.09707911312580109,
-0.0639670267701149,
0.023187341168522835,
0.06203148886561394,
0.007071974221616983,
0.0258175116032362,
-0.03627375140786171,
-0.03413908928632736,
0.008065701462328434,
-0.05005853995680809,
0.003261208301410079,
-0.04544641822576523
] |
PMID:18782669 | Hydrazide derivatives of Ilomastat, carrying either aryl groups or distinct alkyl and arylsulfonyl moieties were synthesized and evaluated for their MMP inhibitory activity. | [
-0.06892402470111847,
-0.008592513389885426,
-0.025617633014917374,
-0.02447470836341381,
0.04494589939713478,
0.0038294487167149782,
0.040492113679647446,
0.059762317687273026,
0.09263287484645844,
0.03983844816684723,
-0.004347918089479208,
0.014979562722146511,
-0.047480616718530655,
-0.0031648240983486176,
-0.05958668515086174,
0.10355313122272491,
0.03732772544026375,
0.06638792902231216,
0.07134179770946503,
0.06736014038324356,
-0.038327328860759735,
-0.08088855445384979,
0.05669314041733742,
-0.017802100628614426,
0.03603608161211014,
0.13758495450019836,
0.08401038497686386,
0.020141588523983955,
-0.028990551829338074,
-0.03897016495466232,
-0.00300283869728446,
-0.02225189283490181,
0.03353586047887802,
-0.09859398752450943,
-0.05045033618807793,
0.05885518342256546,
-0.05400830879807472,
-0.013752073980867863,
-0.022589534521102905,
0.022609271109104156,
0.07538764178752899,
-0.04448823630809784,
0.021268153563141823,
-0.027776166796684265,
-0.008752154186367989,
-0.07565585523843765,
-0.0766649916768074,
0.051883649080991745,
-0.042547807097435,
0.14250712096691132,
-0.011166307143867016,
-0.018612926825881004,
-0.021098842844367027,
0.005830102134495974,
-0.03468013554811478,
-0.06290128827095032,
-0.08795443177223206,
0.07409422844648361,
-0.04465404525399208,
-0.017668062821030617,
0.07192129641771317,
0.05069933459162712,
-0.03860337659716606,
0.015502654016017914,
-0.057440970093011856,
0.05149812251329422,
-0.012967952527105808,
-0.026717107743024826,
0.08037303388118744,
0.004770629107952118,
-0.08935514837503433,
-0.013586966320872307,
-0.012182467617094517,
0.06841457635164261,
-0.04134158417582512,
0.03393730893731117,
0.054531097412109375,
-0.03937264159321785,
0.06276298314332962,
0.008452634327113628,
0.01373921986669302,
0.02911641076207161,
0.14113329350948334,
0.055081967264413834,
0.02335490845143795,
0.08039794862270355,
0.0022099348716437817,
0.08214951306581497,
0.057273369282484055,
-0.04037852957844734,
0.03768729418516159,
0.08638881891965866,
-0.02265593409538269,
-0.008296542800962925,
0.03085741028189659,
0.015449490398168564,
0.0264850202947855,
0.07017245888710022,
-0.01922035403549671,
-0.00495001720264554,
0.016501713544130325,
0.02267060987651348,
-0.1133025512099266,
-0.042280759662389755,
-0.0212449561804533,
0.0022224015556275845,
0.018631644546985626,
-0.03239748626947403,
-0.0320516973733902,
-0.02516971342265606,
-0.08504853397607803,
-0.040562842041254044,
0.0029756140429526567,
-0.023243218660354614,
-0.04447107017040253,
0.04155457019805908,
0.00004953352618031204,
-0.03020797111093998,
-0.0016086456598713994,
-0.037123605608940125,
-0.037654630839824677,
-0.0390402115881443,
0.028559066355228424,
-0.018434949219226837,
0.022409962490200996,
0.07721087336540222,
-0.02268994227051735,
1.5368213859623924e-33,
0.017581209540367126,
0.011754751205444336,
0.0070084272883832455,
0.04080705717206001,
-0.032001346349716187,
0.018550189211964607,
0.004261822905391455,
-0.06844150274991989,
-0.09074728935956955,
-0.04394618049263954,
-0.05467599630355835,
-0.09149623662233353,
-0.008679055608808994,
-0.02951895073056221,
0.05973608046770096,
0.035499390214681625,
0.10080530494451523,
-0.026950586587190628,
0.04729294404387474,
-0.07779516279697418,
0.04948091134428978,
0.10014927387237549,
-0.05351753160357475,
-0.00005227568908594549,
-0.06449314951896667,
0.03887631744146347,
0.04501641169190407,
0.025066323578357697,
-0.0018431964563205838,
-0.0139964884147048,
-0.02220004051923752,
0.0016178871737793088,
-0.09295102208852768,
-0.0021905701141804457,
-0.04762168601155281,
0.016851259395480156,
-0.1131945475935936,
-0.08570580184459686,
0.06893567740917206,
-0.004627563524991274,
-0.089886374771595,
-0.010219177231192589,
-0.005537375807762146,
-0.04297282546758652,
-0.03013754077255726,
-0.0023013674654066563,
-0.05684392899274826,
0.02186628431081772,
0.05854377895593643,
-0.08759145438671112,
0.00942067801952362,
0.058187007904052734,
-0.01029626838862896,
0.0992385596036911,
-0.06756501644849777,
0.04039163514971733,
-0.09503807872533798,
-0.011580415070056915,
0.003744180779904127,
0.016947224736213684,
0.0004473098961170763,
-0.06239130347967148,
0.040835607796907425,
0.03522340953350067,
0.017559640109539032,
0.023878416046500206,
-0.013744151219725609,
-0.007561500184237957,
0.003219065023586154,
0.0677136480808258,
0.054007284343242645,
-0.0428464449942112,
0.09697344899177551,
0.061050739139318466,
0.05731850489974022,
0.019555769860744476,
0.05921219661831856,
0.007345156744122505,
0.025079848244786263,
0.06380052864551544,
0.0041757854633033276,
-0.04401803016662598,
0.05723191797733307,
0.025703497231006622,
0.02350817434489727,
-0.046327922493219376,
-0.03325609490275383,
0.011468526907265186,
0.049473583698272705,
0.014678792096674442,
-0.03336365520954132,
-0.009298346005380154,
-0.11335939913988113,
0.013057506643235683,
-0.01686798967421055,
-2.4383630130702033e-33,
0.11597973108291626,
-0.046883054077625275,
-0.02279640920460224,
-0.028909867629408836,
-0.10083667188882828,
0.025995437055826187,
-0.000977554009296,
-0.0901511013507843,
0.06177721545100212,
0.058807652443647385,
0.12048077583312988,
0.017741335555911064,
-0.00906097237020731,
-0.09667672961950302,
-0.029823847115039825,
0.019552672281861305,
0.046991635113954544,
-0.06529074162244797,
0.007375421933829784,
-0.03917689248919487,
-0.03284187614917755,
0.00451223598793149,
0.013659793883562088,
-0.00047649588668718934,
-0.023855973035097122,
-0.03617154061794281,
0.051018621772527695,
-0.09750664234161377,
-0.003146753180772066,
0.05935652181506157,
0.0015169266844168305,
0.04560863971710205,
-0.03873836621642113,
-0.03876641020178795,
0.07131429761648178,
0.022661563009023666,
-0.014809256419539452,
-0.009757766500115395,
-0.10268469899892807,
0.033075105398893356,
-0.006555868778377771,
-0.09229812026023865,
0.0073114377446472645,
-0.0604468397796154,
0.05866070091724396,
-0.0012991209514439106,
-0.05168267339468002,
-0.02624363824725151,
-0.03674938157200813,
-0.0887821689248085,
-0.03787248954176903,
-0.011184386909008026,
0.005162794608622789,
0.026551920920610428,
0.028174959123134613,
0.07787390053272247,
0.020128680393099785,
-0.06654635816812515,
0.06020279601216316,
0.004096467047929764,
0.01995415985584259,
0.05060840770602226,
0.05074663460254669,
-0.10608424991369247,
-0.028073269873857498,
0.11544329673051834,
-0.04102211445569992,
0.0403108149766922,
0.056444428861141205,
-0.0636703297495842,
0.02448359690606594,
-0.0327085517346859,
0.029199909418821335,
0.09267767518758774,
0.018235065042972565,
-0.028533708304166794,
0.04476911202073097,
0.00877841841429472,
-0.008308649994432926,
-0.07038601487874985,
0.1063976138830185,
0.0009222434600815177,
0.019957803189754486,
-0.0534210205078125,
-0.11820720881223679,
0.018741676583886147,
0.05547131970524788,
0.06499670445919037,
-0.06869860738515854,
0.0315483883023262,
0.05747090280056,
-0.004040924366563559,
-0.03731342777609825,
0.12098982185125351,
0.04149176552891731,
-2.6525080798478484e-8,
-0.05150672793388367,
0.017936253920197487,
-0.01984887383878231,
-0.03069205768406391,
-0.1285688430070877,
0.01758846454322338,
-0.06882345676422119,
0.028002876788377762,
0.0023794416338205338,
-0.006970799993723631,
-0.016010962426662445,
-0.02860925905406475,
0.0511183962225914,
0.04984913766384125,
-0.003167850896716118,
-0.03782336786389351,
0.050540562719106674,
-0.017345555126667023,
-0.041427131742239,
-0.030875960364937782,
-0.05465532839298248,
0.05220527574419975,
0.023358579725027084,
-0.03153812140226364,
-0.0042955344542860985,
-0.00840301439166069,
-0.005808579735457897,
-0.05799445882439613,
0.05950837582349777,
-0.00031736327218823135,
-0.06445840001106262,
0.042674627155065536,
0.01406974159181118,
0.03166859224438667,
0.05337623506784439,
0.11177923530340195,
-0.00390879949554801,
-0.08094022423028946,
0.019243860617280006,
0.02968544326722622,
0.00320407934486866,
-0.042078226804733276,
0.054895661771297455,
0.033775847405195236,
0.0039884173311293125,
-0.0007909805863164365,
0.02209196239709854,
-0.012822444550693035,
-0.03669067099690437,
0.006789463106542826,
-0.03340424597263336,
0.035332754254341125,
-0.027693243697285652,
-0.06247430667281151,
0.021701226010918617,
0.0122893787920475,
-0.0367329977452755,
-0.05206846073269844,
-0.018443645909428596,
-0.10305710136890411,
0.003754114732146263,
-0.1248435229063034,
0.05325314402580261,
-0.03518589958548546
] |
PMID:18782669 | Potent and selective MMP-9 inhibition (IC(50)=3 nM) was observed for compound 3m (arylsulfonyl group: 4-(4-Br-C6H4)-C6H4-SO(2)-). | [
0.029360836371779442,
-0.07229002565145493,
-0.05259668454527855,
-0.022942446172237396,
0.06523982435464859,
0.1058441773056984,
-0.00793179776519537,
0.043327219784259796,
0.01940014399588108,
0.031081128865480423,
0.05680786818265915,
0.018653040751814842,
-0.10389038175344467,
0.021686740219593048,
-0.01820317842066288,
0.09912530332803726,
0.0254555381834507,
0.06136704236268997,
0.06484862416982651,
0.03596441447734833,
-0.00824722833931446,
-0.052227865904569626,
0.050253286957740784,
0.013988588005304337,
0.029747972264885902,
0.1121264398097992,
0.004251859616488218,
0.01591956429183483,
-0.023161111399531364,
-0.043464332818984985,
0.029052918776869774,
0.06434011459350586,
0.03704147785902023,
-0.053078144788742065,
-0.04530470445752144,
-0.0017301333136856556,
-0.09090431034564972,
-0.00031606556149199605,
-0.03633284941315651,
0.047349657863378525,
-0.007207727525383234,
-0.08533298969268799,
-0.015757031738758087,
-0.04259654879570007,
0.04497317597270012,
-0.06354175508022308,
-0.06289709359407425,
0.044208161532878876,
-0.04435794800519943,
0.06544774770736694,
0.03230427950620651,
0.01901664398610592,
-0.03627653047442436,
0.06436725705862045,
-0.03865758329629898,
-0.08136157691478729,
-0.09748733788728714,
0.09054205566644669,
0.004974572919309139,
0.006779729854315519,
0.018044987693428993,
0.040930572897195816,
0.041885796934366226,
0.0190815981477499,
0.02697603590786457,
0.05175016075372696,
0.020594138652086258,
-0.03495365381240845,
0.06725005060434341,
0.08153755962848663,
-0.004474585875868797,
-0.06147818639874458,
-0.009341832250356674,
-0.020558174699544907,
0.021153343841433525,
0.04901539161801338,
0.010571153834462166,
0.008216761983931065,
0.03356392681598663,
-0.003957164939492941,
0.08877011388540268,
0.05662151426076889,
0.12228018790483475,
0.07996975630521774,
0.04510354995727539,
0.02295747399330139,
0.01989564672112465,
0.08837144821882248,
-0.0012511424720287323,
-0.019203323870897293,
0.03287215903401375,
0.04474836587905884,
-0.07684056460857391,
0.0023369353730231524,
-0.031354133039712906,
0.006208448205143213,
-0.005538532510399818,
0.01559292059391737,
-0.030470354482531548,
0.004753531888127327,
0.04788918048143387,
0.029801446944475174,
-0.1281598061323166,
-0.047449517995119095,
0.05077226087450981,
0.04133477807044983,
0.035228874534368515,
-0.0334332175552845,
0.01605585776269436,
-0.04485759884119034,
-0.023016180843114853,
-0.02636309154331684,
-0.08382020145654678,
-0.04222039878368378,
0.0017562427092343569,
0.00979433860629797,
0.08100026845932007,
-0.015427409671247005,
0.03113461099565029,
0.014727337285876274,
-0.023883314803242683,
-0.007600785233080387,
-0.00015304534463211894,
-0.0014337864704430103,
-0.028348170220851898,
0.07228435575962067,
-0.03239089995622635,
4.19629580477723e-34,
-0.011790395714342594,
0.04663485661149025,
0.04739571362733841,
-0.023885920643806458,
-0.005070152226835489,
-0.10013154149055481,
-0.06293758004903793,
0.005988973658531904,
-0.04047028720378876,
-0.014193381182849407,
-0.08310715109109879,
-0.15380418300628662,
0.04954565316438675,
0.009562898427248001,
0.09481395781040192,
-0.023247698321938515,
0.018994946032762527,
0.0004365782660897821,
0.13485781848430634,
-0.15903769433498383,
-0.01604238711297512,
0.0438554510474205,
-0.06845082342624664,
0.01072334311902523,
-0.013532241806387901,
0.029836630448698997,
-0.0067884912714362144,
0.05353206768631935,
0.028516752645373344,
-0.046070050448179245,
0.03540896996855736,
0.00610993942245841,
-0.08946559578180313,
-0.06664974987506866,
-0.04543277621269226,
-0.030147045850753784,
-0.07252617925405502,
-0.10308396816253662,
0.02186589129269123,
-0.036289867013692856,
-0.0815323069691658,
0.014367759227752686,
0.008419753052294254,
-0.03689265996217728,
0.017864108085632324,
-0.08077686280012131,
-0.11341052502393723,
-0.022324685007333755,
0.05805182084441185,
0.006946914363652468,
0.07994739711284637,
0.010723189450800419,
0.032310355454683304,
0.11498702317476273,
-0.028316251933574677,
0.029369480907917023,
-0.06350664049386978,
0.05761149525642395,
0.03616685792803764,
0.049202270805835724,
0.012859191745519638,
-0.08770696818828583,
0.006380138453096151,
0.04015175625681877,
0.04706048220396042,
0.02338264323771,
-0.003941007424145937,
-0.013857543468475342,
-0.05334637314081192,
0.011755583807826042,
0.013446521945297718,
-0.06309083849191666,
0.08717719465494156,
-0.005122869275510311,
0.01028485782444477,
0.0841328501701355,
0.04670409485697746,
0.05443170294165611,
0.05897851288318634,
0.04086572304368019,
0.03127562999725342,
-0.04270046576857567,
-0.034592706710100174,
0.03780844807624817,
-0.04601594805717468,
-0.020632537081837654,
-0.013525187969207764,
-0.04532632976770401,
0.020289240404963493,
0.042325980961322784,
0.06119946390390396,
-0.05198981985449791,
-0.04695327952504158,
0.021304534748196602,
-0.06810890138149261,
-9.383919056381511e-34,
0.09189613908529282,
-0.011899531818926334,
0.011103770695626736,
-0.03337014466524124,
-0.09951092302799225,
0.04497653990983963,
0.041717205196619034,
-0.0979386419057846,
0.000515851890668273,
0.04763190820813179,
0.0873090848326683,
-0.02674155682325363,
0.04394245147705078,
-0.08995133638381958,
0.001512737711891532,
0.008529591374099255,
0.040649522095918655,
0.0012766014551743865,
0.05933450162410736,
0.028769249096512794,
0.03532334789633751,
0.0024908294435590506,
0.00594031298533082,
0.061633385717868805,
-0.0774812176823616,
-0.012227160856127739,
0.06768179684877396,
-0.0676310583949089,
0.02682451345026493,
0.07192396372556686,
0.03433303162455559,
-0.009449779987335205,
-0.07806558161973953,
-0.02065175026655197,
0.06816742569208145,
0.006471107713878155,
0.027301570400595665,
0.03510947898030281,
-0.08624571561813354,
0.005246493499726057,
-0.009954887442290783,
-0.005037303082644939,
-0.06833849847316742,
0.002138450974598527,
0.06428670138120651,
0.020046645775437355,
0.013208501972258091,
0.03697416931390762,
0.014322448521852493,
-0.06347764283418655,
-0.080668143928051,
-0.009359654039144516,
-0.015796363353729248,
-0.05397333577275276,
0.024239908903837204,
0.02457226626574993,
0.025061506778001785,
-0.1482113003730774,
0.006656546611338854,
0.001957634696736932,
-0.004675691481679678,
0.05895885080099106,
0.006120591890066862,
-0.098834328353405,
0.0119993407279253,
0.10948177427053452,
-0.02512224018573761,
0.057676348835229874,
0.023585934191942215,
-0.1317553073167801,
-0.006016320548951626,
-0.0069441297091543674,
0.04723406583070755,
0.06943535804748535,
-0.032855283468961716,
-0.07763142138719559,
0.10106969624757767,
-0.006389561574906111,
0.025932831689715385,
-0.025383178144693375,
0.06277105212211609,
-0.05030173435807228,
-0.02076064981520176,
-0.06676308065652847,
-0.06573612242937088,
-0.04014639928936958,
0.058763500303030014,
0.04177860543131828,
0.002639635233208537,
-0.016178343445062637,
0.082220658659935,
0.03751014545559883,
-0.005738752894103527,
0.015601182356476784,
0.015667449682950974,
-3.2556105367120836e-8,
0.06902172416448593,
-0.027554063126444817,
0.09943430870771408,
-0.09142650663852692,
-0.048559583723545074,
-0.005467117298394442,
0.01642853394150734,
0.02484443411231041,
-0.049219705164432526,
-0.0016052176943048835,
0.04695013910531998,
-0.022821111604571342,
-0.038797423243522644,
-0.0072213574312627316,
0.08997522294521332,
-0.08139528334140778,
-0.03392808139324188,
0.002073807641863823,
-0.01580602303147316,
-0.07396925985813141,
-0.06584399938583374,
-0.01631815731525421,
0.031040485948324203,
-0.05674947798252106,
0.043045658618211746,
0.009359132498502731,
0.07074742019176483,
0.015439500100910664,
0.03122863918542862,
-0.02778848260641098,
0.0282086543738842,
0.026527946814894676,
-0.02480052411556244,
0.06760279834270477,
0.041930533945560455,
-0.004809673875570297,
0.002872990909963846,
-0.00028992295847274363,
-0.01815984584391117,
0.04985247924923897,
-0.10460593551397324,
-0.03998073935508728,
0.009453877806663513,
0.021209105849266052,
-0.03235827386379242,
0.028199821710586548,
0.0060250782407820225,
0.054652247577905655,
-0.02469986118376255,
-0.04987668618559837,
-0.007821770384907722,
0.0029207535553723574,
-0.048433128744363785,
-0.0372575968503952,
-0.07542484253644943,
-0.02583417296409607,
-0.004172048531472683,
-0.03550068289041519,
-0.0028612660244107246,
-0.10776732116937637,
-0.006891213357448578,
-0.09286555647850037,
0.01885812170803547,
-0.027989594265818596
] |
PMID:18782669 | Interaction with the S2 enzyme subsite is mainly responsible for the inhibitory properties of this derivative as confirmed by molecular docking computation. | [
-0.01693549193441868,
-0.08370349556207657,
-0.04067927971482277,
0.013112487271428108,
0.09136742353439331,
-0.021028168499469757,
-0.09050722420215607,
0.05149497091770172,
0.047639716416597366,
0.025553053244948387,
0.004434047732502222,
0.02604534849524498,
0.01249813474714756,
0.0560075044631958,
-0.04386237636208534,
0.050705183297395706,
0.00367338745854795,
0.040762368589639664,
0.054055508226156235,
0.009769370779395103,
0.0008155229734256864,
0.007169242948293686,
0.012679137289524078,
-0.010655784048140049,
-0.011026984080672264,
0.021063514053821564,
-0.0023105116561055183,
-0.0033585592173039913,
-0.0021545314230024815,
-0.062162864953279495,
0.010182557627558708,
0.04931538924574852,
0.05435539036989212,
-0.07997502386569977,
0.012082606554031372,
-0.02717817761003971,
0.025595571845769882,
-0.01121913269162178,
-0.0014557928079739213,
-0.018972156569361687,
0.08924023807048798,
-0.005677171051502228,
0.015336643904447556,
-0.06794020533561707,
0.01024633552879095,
-0.06927888095378876,
-0.023591745644807816,
-0.025287004187703133,
-0.012647975236177444,
0.08439356833696365,
-0.0001810447865864262,
-0.051241684705019,
-0.06842488795518875,
-0.03057803586125374,
-0.024284491315484047,
0.10036195069551468,
-0.03209220618009567,
0.05677485466003418,
0.007624308578670025,
-0.052144452929496765,
0.06685509532690048,
-0.05898404121398926,
0.03481888398528099,
-0.01590820401906967,
0.11845996230840683,
-0.04664638638496399,
0.06284371763467789,
-0.030336696654558182,
0.024552009999752045,
0.036398258060216904,
-0.056608472019433975,
-0.026653973385691643,
-0.0506889708340168,
0.01995045132935047,
0.030230917036533356,
0.00033435746445320547,
0.0015129637904465199,
0.04685007035732269,
0.07514945417642593,
-0.03353201597929001,
0.02975606545805931,
-0.036280129104852676,
0.023759016767144203,
0.06145481765270233,
-0.009463039226830006,
0.025011658668518066,
0.01797993667423725,
0.017519330605864525,
0.03117588721215725,
-0.037195585668087006,
0.07605277001857758,
-0.07496210932731628,
-0.08112191408872604,
-0.05723356083035469,
-0.04205532371997833,
0.02090338245034218,
-0.03787687048316002,
0.04106567054986954,
0.0032110048923641443,
-0.05331429839134216,
0.050143636763095856,
0.04535755515098572,
-0.07538196444511414,
-0.09119754284620285,
0.03114553540945053,
0.016365470364689827,
0.010525312274694443,
0.026180775836110115,
-0.0062083033844828606,
-0.042331039905548096,
0.04009699076414108,
0.006834108382463455,
0.08271238952875137,
0.04843281954526901,
-0.04482404142618179,
0.0751304179430008,
0.1001884937286377,
-0.03544468432664871,
0.024200638756155968,
-0.017120834439992905,
0.0634135976433754,
-0.0012615792220458388,
0.057328805327415466,
-0.004062434192746878,
-0.03898865357041359,
0.017177877947688103,
-0.11627787351608276,
-2.2973902000089097e-33,
0.023237571120262146,
-0.023879405111074448,
0.03247450664639473,
0.011322741396725178,
0.06257714331150055,
-0.08035824447870255,
-0.06756149977445602,
0.012550113722682,
-0.07898619025945663,
0.04959268867969513,
-0.13442672789096832,
-0.0537615530192852,
0.08568482846021652,
-0.05206780508160591,
-0.01704976335167885,
-0.01850391924381256,
0.08461682498455048,
-0.00590151222422719,
-0.0012250252766534686,
-0.03579782322049141,
0.05704300105571747,
0.04734688252210617,
-0.01888618990778923,
0.02491338551044464,
0.05972284451127052,
0.050165675580501556,
-0.017075765877962112,
0.033844105899333954,
0.12516309320926666,
-0.003224841319024563,
-0.004695033188909292,
-0.036815542727708817,
-0.07860904932022095,
0.07472880184650421,
0.08019829541444778,
0.0026869862340390682,
0.04902234673500061,
-0.03782776743173599,
0.021109450608491898,
0.025467736646533012,
0.014294002205133438,
-0.02855280414223671,
0.02851266600191593,
-0.01729450188577175,
-0.0004029750998597592,
-0.06339891999959946,
0.003554822411388159,
0.02334987185895443,
-0.018314309418201447,
0.023226067423820496,
-0.012753323651850224,
-0.06056533008813858,
0.03229811415076256,
0.03848867863416672,
-0.0674700140953064,
0.0063244011253118515,
-0.04604058712720871,
-0.013111917302012444,
0.0002103839215124026,
0.05926740914583206,
-0.10283727943897247,
-0.010609357617795467,
-0.0403672456741333,
-0.004586603958159685,
-0.02842012606561184,
0.0704616978764534,
-0.028097862377762794,
-0.0243136715143919,
-0.036113567650318146,
0.0939478650689125,
0.006716345902532339,
0.07797887176275253,
0.05747240036725998,
0.059044573456048965,
0.03090566024184227,
-0.06570687144994736,
-0.050318166613578796,
-0.0042046429589390755,
0.10846155136823654,
0.047378890216350555,
-0.04718298465013504,
-0.02449270524084568,
-0.05994364991784096,
0.061485979706048965,
-0.10275048017501831,
-0.16675692796707153,
-0.05199814960360527,
-0.0466182567179203,
-0.04520004615187645,
0.016327641904354095,
0.05069130286574364,
0.004141812678426504,
-0.014316956512629986,
-0.02199288085103035,
0.014619412831962109,
-9.803790944815847e-34,
0.026139037683606148,
-0.08476974815130234,
0.02225140482187271,
-0.05382645130157471,
-0.09842789173126221,
0.0772785022854805,
0.04927080124616623,
-0.08265809714794159,
0.06057655066251755,
-0.023491695523262024,
0.07510601729154587,
0.0431329645216465,
-0.021415693685412407,
-0.05804784595966339,
-0.026493724435567856,
0.04971318691968918,
-0.05636070668697357,
-0.031263209879398346,
0.012395028956234455,
-0.0443744920194149,
-0.017573563382029533,
0.04195919260382652,
0.0857774168252945,
0.10828935354948044,
-0.009684581309556961,
-0.04442945867776871,
0.050105784088373184,
0.015180970542132854,
0.04062153771519661,
0.08990062028169632,
-0.04080625995993614,
-0.02013254351913929,
-0.07853012531995773,
0.004329686984419823,
-0.06431727111339569,
0.04893212392926216,
-0.05092253535985947,
0.02966778725385666,
-0.04329345375299454,
-0.045155785977840424,
0.048960600048303604,
0.04909813404083252,
-0.013221470639109612,
0.0728033035993576,
0.1261277198791504,
-0.0011098086833953857,
-0.08185804635286331,
0.07462100684642792,
-0.02974294126033783,
-0.11157623678445816,
-0.044277966022491455,
-0.08482161164283752,
0.008543174713850021,
-0.019279135391116142,
-0.008611750788986683,
0.02502470463514328,
-0.013300670310854912,
-0.034489016979932785,
-0.03160446509718895,
-0.014417710714042187,
-0.014228002168238163,
-0.05144758149981499,
-0.03373309224843979,
0.0428934283554554,
-0.043419357389211655,
0.04554549977183342,
-0.06436149775981903,
0.08373938500881195,
0.054327595978975296,
-0.05984919145703316,
0.026859773322939873,
-0.06276191025972366,
0.028343604877591133,
0.06819771230220795,
-0.012036111205816269,
-0.026180444285273552,
-0.002444181125611067,
-0.049274854362010956,
0.09566712379455566,
-0.11220323294401169,
0.00819032359868288,
0.08342849463224411,
0.0478774830698967,
-0.1130453422665596,
-0.03653319552540779,
-0.04011249169707298,
-0.009224671870470047,
0.14762544631958008,
0.027186308056116104,
-0.04315940663218498,
-0.026622751727700233,
-0.019514767453074455,
-0.06638947874307632,
0.06599259376525879,
0.013199547305703163,
-2.3696495432545817e-8,
0.028806714341044426,
-0.03100016713142395,
0.06679514795541763,
-0.012943906709551811,
-0.03548466041684151,
0.057688530534505844,
-0.00018347128934692591,
0.04632944613695145,
0.030056757852435112,
0.0053437319584190845,
-0.08909294754266739,
0.01591268740594387,
-0.05091582238674164,
-0.028901798650622368,
0.04566080495715141,
0.12796886265277863,
-0.010640048421919346,
0.05791305750608444,
-0.07140658050775528,
-0.027057094499468803,
-0.03382563591003418,
0.01691352389752865,
-0.028603585436940193,
-0.017015915364027023,
0.050179094076156616,
-0.06951609998941422,
-0.04808473587036133,
0.020541593432426453,
-0.03203386068344116,
-0.09001532942056656,
0.027209950610995293,
-0.020754799246788025,
-0.03009689785540104,
0.07932782173156738,
-0.009972202591598034,
0.013254741206765175,
-0.02668450027704239,
-0.07471932470798492,
0.0389191135764122,
0.07598955184221268,
-0.02687145583331585,
-0.009987191297113895,
-0.035796232521533966,
-0.0605115070939064,
-0.039140138775110245,
0.03235716372728348,
0.06572938710451126,
0.04198018088936806,
0.013145621865987778,
0.027828067541122437,
0.012327654287219048,
-0.02077336236834526,
-0.06172287091612816,
-0.08977693319320679,
-0.02090153656899929,
0.00412842258810997,
-0.04219980910420418,
-0.05174623429775238,
0.041666071861982346,
-0.06202072650194168,
0.019960718229413033,
0.04294312745332718,
0.0761926919221878,
-0.04052925109863281
] |
PMID:14684295 | The synthesis and MMP inhibitory activity of a series of tetrahydroisoquinoline based sulfonamide hydroxamates are described. | [
-0.004564287606626749,
-0.08492721617221832,
0.008656454272568226,
-0.024129630997776985,
-0.04376635327935219,
0.051354214549064636,
-0.07539355754852295,
0.050195641815662384,
0.04013185575604439,
-0.03950098901987076,
0.0184852983802557,
0.014024303294718266,
-0.02134726196527481,
-0.007550953421741724,
-0.04527895897626877,
0.12272656708955765,
-0.029855310916900635,
0.04588022083044052,
0.0903422012925148,
0.035832323133945465,
-0.086958147585392,
-0.04770604521036148,
-0.04183607175946236,
0.02367272600531578,
0.02068025805056095,
0.17388339340686798,
-0.01862558163702488,
0.06779433786869049,
-0.06360483169555664,
0.04414504021406174,
0.08978342264890671,
0.052266404032707214,
0.011926226317882538,
-0.10442947596311569,
-0.028861641883850098,
0.04533735662698746,
-0.11311003565788269,
0.0001598363451194018,
-0.07040558755397797,
-0.05140959098935127,
0.01002163253724575,
-0.06574047356843948,
-0.0456402413547039,
-0.08339979499578476,
0.02668914571404457,
-0.08756031095981598,
-0.019860299304127693,
0.06145578622817993,
0.006629949901252985,
0.05414982885122299,
-0.06815166026353836,
-0.0445965901017189,
-0.08176949620246887,
0.10413745790719986,
0.02157003991305828,
-0.029260290786623955,
0.01053026132285595,
0.12152498960494995,
0.031889647245407104,
-0.007651739753782749,
-0.006125453859567642,
0.08008313179016113,
0.010858438909053802,
0.003966532181948423,
-0.01566942036151886,
0.049198031425476074,
-0.004371213261038065,
-0.043551571667194366,
0.08669564127922058,
0.018922656774520874,
-0.09731962531805038,
-0.03339938446879387,
0.04437079280614853,
0.013791664503514767,
-0.05073261260986328,
0.0569961816072464,
0.010780079290270805,
-0.023383203893899918,
0.14641700685024261,
-0.0038401323836296797,
-0.0030401137191802263,
-0.054481156170368195,
0.030338598415255547,
0.08503048121929169,
0.023866912350058556,
-0.005544749554246664,
0.0440337099134922,
-0.030554523691534996,
0.11276306211948395,
-0.005733397789299488,
-0.04658224433660507,
0.036370791494846344,
-0.039050329476594925,
0.004107536282390356,
0.04150938615202904,
0.03816806897521019,
-0.06124826893210411,
0.12773366272449493,
-0.009641616605222225,
-0.022334963083267212,
0.051538582891225815,
-0.020914804190397263,
-0.11217208951711655,
-0.07024311274290085,
-0.01409774087369442,
0.020479043945670128,
0.04827124997973442,
-0.018820879980921745,
-0.01553537230938673,
-0.022381898015737534,
-0.03503367677330971,
-0.034967001527547836,
-0.006506206467747688,
-0.05913538485765457,
-0.030799219384789467,
0.05648503452539444,
0.06815849989652634,
0.0025979098863899708,
-0.059172261506319046,
-0.02445080503821373,
-0.020096277818083763,
0.016680682078003883,
0.0036788652651011944,
-0.036669228225946426,
0.023343941196799278,
0.014713260345160961,
0.029901692643761635,
3.5896351663295326e-35,
0.07959543168544769,
0.06258759647607803,
0.05928543582558632,
0.024854568764567375,
-0.03348981589078903,
-0.017376136034727097,
-0.059454966336488724,
0.0371091403067112,
-0.04125411435961723,
-0.03520428389310837,
-0.02748166397213936,
-0.0008672231342643499,
-0.004161667078733444,
-0.009994539432227612,
-0.01562773808836937,
-0.04675304889678955,
0.04868033900856972,
-0.042573053389787674,
0.11063046753406525,
-0.07717899978160858,
-0.029834706336259842,
0.033023569732904434,
-0.022243686020374298,
-0.013249688781797886,
-0.06706290692090988,
0.025013841688632965,
-0.044643793255090714,
0.011871138587594032,
0.009635711088776588,
0.0018880699062719941,
-0.0032827111426740885,
-0.05525541305541992,
-0.13395124673843384,
-0.04296775162220001,
0.02073611505329609,
0.006511729210615158,
-0.12459000200033188,
-0.054138023406267166,
0.0041445218957960606,
0.030953744426369667,
-0.01589549519121647,
0.03211533650755882,
0.024984611198306084,
-0.05417121946811676,
-0.024813538417220116,
0.0049742115661501884,
-0.05821717157959938,
-0.005155108403414488,
0.07447835803031921,
-0.024358326569199562,
0.046290501952171326,
-0.012513549998402596,
-0.00020240890444256365,
0.046143416315317154,
-0.04800773039460182,
0.007595536299049854,
-0.015142400749027729,
0.04172235354781151,
0.004122214857488871,
0.001124981907196343,
-0.05410091578960419,
0.007397383917123079,
0.017704905942082405,
-0.014241427183151245,
-0.016304967924952507,
-0.027821097522974014,
0.055872730910778046,
0.0724906325340271,
0.004126532468944788,
-0.044470030814409256,
0.010847018100321293,
0.018839366734027863,
0.09346716850996017,
0.03534102439880371,
0.012266602367162704,
0.020994868129491806,
0.07997685670852661,
-0.031587883830070496,
0.06349031627178192,
0.03278734162449837,
-0.032255154103040695,
-0.07238563895225525,
0.0017857624916359782,
-0.00667297700420022,
-0.07953480631113052,
0.003922258969396353,
-0.02956487238407135,
0.06058298796415329,
-0.015771308913826942,
0.02076706662774086,
0.01767759397625923,
-0.019402842968702316,
-0.034997548907995224,
0.03401369974017143,
0.03317301720380783,
-1.9646602791949224e-33,
0.028774676844477654,
-0.034821897745132446,
0.02733157016336918,
-0.07267624884843826,
-0.0641370639204979,
-0.00008118538971757516,
0.03625814616680145,
-0.04845234379172325,
0.05355144292116165,
0.052231565117836,
0.0783524140715599,
-0.0400746688246727,
0.041446421295404434,
-0.07784086465835571,
-0.030787253752350807,
0.00017362112703267485,
0.0768335685133934,
-0.015981312841176987,
0.0591881237924099,
-0.060196779668331146,
0.06192556768655777,
0.040373142808675766,
-0.020709766075015068,
0.0876569002866745,
-0.049232836812734604,
0.047758106142282486,
0.09109767526388168,
-0.10967157781124115,
0.07923061400651932,
0.1036570742726326,
0.04517904669046402,
0.030457403510808945,
-0.012179745361208916,
-0.03977392613887787,
0.06935423612594604,
0.05494849383831024,
-0.014982986263930798,
0.02690727263689041,
-0.010331940837204456,
-0.007245207205414772,
0.031882889568805695,
-0.02032793127000332,
-0.02020752616226673,
-0.008207214064896107,
0.019649967551231384,
0.04655136540532112,
0.01435018889605999,
-0.0018784984713420272,
-0.029921485111117363,
0.008472410030663013,
0.04289357364177704,
0.0009047947824001312,
-0.09431780129671097,
-0.03357309103012085,
0.005560480058193207,
0.03383317589759827,
-0.01838551089167595,
-0.09095817059278488,
0.03838455304503441,
-0.0661831647157669,
-0.02445385418832302,
-0.011528444476425648,
0.005393218714743853,
-0.09535985440015793,
-0.09140267223119736,
0.19267494976520538,
-0.00521714985370636,
0.006927380803972483,
0.007908852770924568,
-0.100213922560215,
-0.013917729258537292,
-0.009390491060912609,
0.03961402550339699,
0.012415224686264992,
-0.018669525161385536,
-0.03947281464934349,
0.07077861577272415,
0.04229508712887764,
0.0047381860204041,
-0.06820060312747955,
0.1264229118824005,
0.03984421491622925,
0.027340320870280266,
-0.07891008257865906,
-0.017716314643621445,
-0.03363035246729851,
-0.0655292198061943,
0.046923570334911346,
-0.028866663575172424,
0.03102915920317173,
0.013503840193152428,
0.05637584999203682,
-0.007122496142983437,
0.03216368705034256,
0.03024906851351261,
-2.477323413074828e-8,
-0.01935235969722271,
-0.007632220163941383,
0.04072697088122368,
0.0056069521233439445,
-0.04354365915060043,
0.050314050167798996,
-0.01655295118689537,
0.0015246851835399866,
0.016881173476576805,
0.0033288781996816397,
0.043436720967292786,
0.02116142399609089,
0.01722269132733345,
0.02371271327137947,
0.015138101764023304,
0.0006337594240903854,
-0.045810721814632416,
-0.06633341312408447,
-0.04427434131503105,
-0.04117627441883087,
-0.021869665011763573,
0.021986601874232292,
-0.046707794070243835,
-0.02085307240486145,
0.029545988887548447,
-0.06278310716152191,
0.021480491384863853,
-0.06305668503046036,
-0.03291681408882141,
-0.01667691022157669,
0.020231077447533607,
0.06136241927742958,
-0.0848030298948288,
0.0033491458743810654,
0.016959061846137047,
0.04268192499876022,
0.019602784886956215,
-0.04896620288491249,
-0.04404405504465103,
0.02013653889298439,
-0.05922587588429451,
-0.0005320008494891226,
-0.03732621297240257,
-0.009802721440792084,
0.013432623818516731,
-0.0047189025208354,
0.005896664224565029,
0.0602966733276844,
-0.07559839636087418,
0.029679546132683754,
0.03127695247530937,
0.018486561253666878,
0.006351932417601347,
-0.06296221911907196,
-0.04695519432425499,
0.031114725396037102,
0.03219782933592796,
-0.04179355129599571,
-0.051758237183094025,
-0.17312484979629517,
-0.045951128005981445,
-0.15938468277454376,
0.10251468420028687,
-0.03980836272239685
] |
PMID:14684295 | In nine MMPs tested, most of the compounds display potent inhibition activity except for MMP-7. | [
-0.006659928243607283,
-0.0727682039141655,
0.021541178226470947,
0.040128372609615326,
0.02602677047252655,
0.06425792723894119,
0.006281591020524502,
0.10007062554359436,
0.006423196755349636,
0.06488066911697388,
-0.0022519375197589397,
0.012507593259215355,
-0.07251660525798798,
0.061296865344047546,
-0.0779930129647255,
0.05950501188635826,
0.07682077586650848,
0.03738635778427124,
0.08955416828393936,
0.06069691851735115,
-0.00650753453373909,
-0.013977143913507462,
0.03787141293287277,
0.03370072320103645,
0.02689267136156559,
0.137550488114357,
-0.043206587433815,
0.08100055903196335,
0.003672939958050847,
-0.04630819335579872,
-0.030627010390162468,
0.039513055235147476,
0.0851147398352623,
-0.04636237397789955,
-0.010330847464501858,
-0.022232715040445328,
-0.04879937320947647,
0.053410887718200684,
-0.029067611321806908,
0.026587843894958496,
0.031050724908709526,
-0.1029183566570282,
0.022593675181269646,
-0.08643528819084167,
0.011392546817660332,
-0.08948174864053726,
-0.045515913516283035,
-0.014676474034786224,
-0.08083552122116089,
0.029695041477680206,
-0.0017430172301828861,
-0.04635082185268402,
-0.045849643647670746,
0.1067114993929863,
0.026568174362182617,
-0.13009335100650787,
-0.06787467747926712,
0.09367692470550537,
0.023576317355036736,
0.015519222244620323,
-0.0727139487862587,
0.03896953910589218,
-0.015860440209507942,
0.03278020769357681,
0.05073099210858345,
0.046873871237039566,
-0.010830109007656574,
-0.018831178545951843,
0.05125000700354576,
0.003780440194532275,
-0.024362877011299133,
-0.06042444333434105,
0.010623888112604618,
-0.008674333803355694,
0.049878448247909546,
0.05682880058884621,
-0.017154207453131676,
-0.034864988178014755,
0.028597772121429443,
-0.04063316807150841,
0.05337211862206459,
0.007535033393651247,
0.04770838841795921,
0.02172151207923889,
0.05960432440042496,
-0.0038833855651319027,
-0.003737586783245206,
0.05889122933149338,
-0.008188971318304539,
-0.039996612817049026,
0.0009355046786367893,
0.053830455988645554,
-0.027130577713251114,
-0.03302205353975296,
-0.022947030141949654,
0.009991658851504326,
-0.11162937432527542,
0.058491647243499756,
-0.0773610770702362,
0.008919249288737774,
0.08022511005401611,
0.053023576736450195,
-0.1380639672279358,
-0.014676284044981003,
-0.03721076250076294,
-0.007054252550005913,
0.09567803144454956,
-0.035064391791820526,
-0.02605195716023445,
-0.043964069336652756,
0.009176081977784634,
0.005107976496219635,
-0.02396664023399353,
0.00190003274474293,
0.02734013833105564,
-0.034009724855422974,
0.03443855047225952,
0.006404852494597435,
0.04700535535812378,
0.02975376881659031,
-0.023906903341412544,
-0.06626423448324203,
0.053362924605607986,
-0.038736265152692795,
-0.011481736786663532,
0.07933685928583145,
0.02131464146077633,
-5.41542762830891e-34,
0.004777940455824137,
-0.04914960265159607,
0.05760842189192772,
-0.002308920491486788,
0.013482864014804363,
-0.04315945878624916,
-0.04537930712103844,
-0.059207309037446976,
0.08131203800439835,
-0.020748525857925415,
-0.07400372624397278,
-0.05490303784608841,
0.009239854291081429,
0.023997215554118156,
0.08886917680501938,
0.01858140528202057,
0.03462546691298485,
0.005956515669822693,
0.10833020508289337,
-0.09679750353097916,
0.0366375669836998,
-0.048866599798202515,
-0.08201000094413757,
0.014743035659193993,
0.006371149327605963,
0.10309402644634247,
-0.06596695631742477,
0.11404593288898468,
-0.013318394310772419,
-0.016311796382069588,
-0.06354875862598419,
0.0273987278342247,
-0.06496881693601608,
-0.02336469292640686,
-0.04255155101418495,
0.00357269961386919,
-0.04864171892404556,
-0.07619405537843704,
0.03526138514280319,
-0.046878501772880554,
-0.04012977331876755,
0.0151596087962389,
0.012876860797405243,
-0.02790469489991665,
0.04170695319771767,
-0.03333594277501106,
-0.12458574026823044,
-0.035571105778217316,
-0.007415493950247765,
0.06055985763669014,
0.08107688277959824,
-0.02381288632750511,
0.010794545523822308,
0.02307935245335102,
-0.02156740613281727,
0.0812174528837204,
-0.02265106700360775,
0.014810389839112759,
0.027965981513261795,
0.09114392101764679,
0.003118676133453846,
-0.029392290860414505,
-0.04180673882365227,
-0.01881716400384903,
0.022201646119356155,
0.06047876924276352,
-0.05827018618583679,
-0.04102511703968048,
-0.03802942857146263,
0.05387481302022934,
-0.007746800780296326,
-0.019982123747467995,
0.1036045253276825,
0.000299996929243207,
0.04930833354592323,
0.01239968091249466,
0.020542843267321587,
0.08283974230289459,
0.029252614825963974,
0.03164965286850929,
0.04020942375063896,
-0.10917504131793976,
-0.12513695657253265,
0.004367353394627571,
-0.07121540606021881,
-0.03431239724159241,
-0.0032452745363116264,
-0.0886407345533371,
0.0033325424883514643,
-0.031529899686574936,
0.11809413880109787,
-0.0027769010048359632,
-0.07157968729734421,
0.04576118290424347,
-0.05878780409693718,
-5.312321620884929e-34,
0.02934092842042446,
-0.025632912293076515,
0.04831799864768982,
0.03944240137934685,
-0.06623057276010513,
0.051659248769283295,
0.01682305335998535,
-0.11199933290481567,
0.03311459347605705,
0.0029714833945035934,
0.13368074595928192,
-0.030328745022416115,
-0.008967067115008831,
-0.05103551968932152,
-0.020962605252861977,
0.020976504310965538,
0.018261590972542763,
0.051349904388189316,
0.05895615369081497,
-0.03901198133826256,
0.03315560892224312,
0.04499911516904831,
-0.015532453544437885,
0.0904022753238678,
-0.00447632372379303,
-0.020179269835352898,
-0.02855890616774559,
-0.06280574202537537,
0.04295187070965767,
0.0848705917596817,
0.019147925078868866,
0.05345233529806137,
-0.06957606226205826,
-0.05564677715301514,
0.037391819059848785,
-0.062016308307647705,
-0.004970395006239414,
0.02233751490712166,
-0.08870502561330795,
-0.0024193786084651947,
0.04751748964190483,
0.058279525488615036,
-0.02907370775938034,
-0.007088711950927973,
0.01893683336675167,
0.03868044912815094,
0.07209298759698868,
-0.0346449576318264,
0.007350605446845293,
-0.02985227480530739,
-0.020134015008807182,
0.0234442837536335,
-0.04733618348836899,
-0.04163360595703125,
-0.02522132731974125,
0.0543537363409996,
0.019744543358683586,
-0.054699160158634186,
0.052069149911403656,
0.034512244164943695,
-0.0021485367324203253,
0.04382314905524254,
-0.05213113874197006,
-0.05225127935409546,
0.006284233182668686,
0.13059653341770172,
0.0109703429043293,
0.10404159873723984,
0.06940087676048279,
-0.08848734945058823,
0.030579611659049988,
0.008433518931269646,
0.062358684837818146,
-0.013003419153392315,
-0.04316737502813339,
-0.05413751304149628,
0.043006766587495804,
-0.023252729326486588,
0.018711723387241364,
-0.08127054572105408,
0.013491311110556126,
-0.031626950949430466,
-0.08460813015699387,
-0.07111276686191559,
-0.06230207532644272,
-0.006818847265094519,
-0.001703317859210074,
-0.020797112956643105,
0.007610926404595375,
0.024982577189803123,
0.03574240580201149,
0.01803871989250183,
-0.008466237224638462,
0.007924506440758705,
0.021742483600974083,
-2.2161257717812077e-8,
0.023694036528468132,
-0.058172959834337234,
0.07078149169683456,
-0.049584101885557175,
-0.023569080978631973,
0.007364010438323021,
-0.035559289157390594,
0.03373730927705765,
0.0035001873038709164,
0.03078978694975376,
0.07734973728656769,
-0.010133985430002213,
-0.05645273998379707,
0.02398240938782692,
0.0759957879781723,
-0.005461154505610466,
-0.004980599042028189,
0.01564311608672142,
-0.04521274194121361,
-0.0343974269926548,
-0.03451813384890556,
-0.013724353164434433,
0.010926623828709126,
-0.005239157471805811,
-0.027249323204159737,
-0.042073365300893784,
0.0005038779927417636,
0.051612451672554016,
0.030377188697457314,
-0.07405007630586624,
0.08239268511533737,
0.02757403627038002,
0.002767732832580805,
0.004199219401925802,
-0.017330721020698547,
0.05493239313364029,
0.05365320295095444,
-0.02530263550579548,
-0.04177606850862503,
0.09974727779626846,
-0.10904332995414734,
-0.1049657091498375,
-0.043221574276685715,
0.012252002954483032,
-0.05979808792471886,
0.05292817950248718,
-0.015768110752105713,
0.018759381026029587,
-0.0550357811152935,
-0.013669881038367748,
0.021127671003341675,
0.047211501747369766,
-0.01396885234862566,
-0.08658120036125183,
-0.032630760222673416,
-0.007417718879878521,
0.0644485279917717,
-0.011209500022232533,
-0.01595151796936989,
-0.125472754240036,
0.028903977945446968,
-0.09035424143075943,
0.04953065514564514,
-0.016195885837078094
] |
PMID:14684295 | Some subtle isozyme selectivity is observed by varying the substituents at the 6- and 7-positions and aromatic ring of arylsulfonyl groups. | [
-0.030169807374477386,
-0.1529039442539215,
-0.02163456566631794,
0.007490961346775293,
0.03492572903633118,
0.0763426125049591,
0.062477972358465195,
-0.05521265044808388,
0.04253627359867096,
-0.07294382154941559,
0.08186261355876923,
0.011941996403038502,
-0.07649951428174973,
-0.05258651822805405,
-0.03648725524544716,
0.04313739761710167,
-0.012791585177183151,
0.013821801170706749,
-0.025619369000196457,
-0.012706573121249676,
-0.018340880051255226,
-0.06175428628921509,
0.047879334539175034,
-0.04763692989945412,
0.0807226374745369,
-0.03607109189033508,
0.055911585688591,
0.09871188551187515,
0.025755343958735466,
-0.10607454925775528,
-0.015626778826117516,
0.052890844643116,
0.029575888067483902,
-0.017871880903840065,
-0.006179824937134981,
0.04739104211330414,
0.0011586861219257116,
-0.03014245443046093,
0.0723911002278328,
0.03769194707274437,
-0.01891343854367733,
-0.04649299755692482,
-0.04684797301888466,
-0.047804445028305054,
-0.09843409061431885,
-0.015328058041632175,
0.00424594059586525,
0.03651615232229233,
-0.005805922206491232,
-0.042881112545728683,
0.03830987215042114,
-0.015086452476680279,
0.006901201792061329,
0.08250422775745392,
-0.06107178330421448,
0.0010083395754918456,
-0.045960258692502975,
-0.004614474251866341,
-0.07879763841629028,
0.022810272872447968,
0.03455501049757004,
0.01399132702499628,
-0.048586156219244,
-0.020452814176678658,
-0.043399665504693985,
0.05132564529776573,
0.12140210717916489,
-0.018838360905647278,
0.08876153826713562,
-0.010816667228937149,
-0.007428035140037537,
-0.016912871971726418,
-0.08353821188211441,
0.004735815338790417,
-0.03507125750184059,
0.06972027570009232,
-0.07123325765132904,
-0.061430010944604874,
-0.0006664454122073948,
-0.12295906990766525,
-0.0020997889805585146,
0.03403889015316963,
0.08615411072969437,
0.08481419831514359,
0.03896893560886383,
-0.03419060632586479,
-0.0072586978785693645,
0.058530453592538834,
-0.017492368817329407,
0.011224491521716118,
0.06592743843793869,
0.01073556300252676,
-0.029366903007030487,
-0.009827808476984501,
0.014267311431467533,
0.03151882812380791,
0.08855707943439484,
0.029815763235092163,
-0.020336149260401726,
0.007519787643104792,
0.07278206199407578,
-0.03714188560843468,
-0.076384998857975,
-0.013658836483955383,
-0.011350740678608418,
0.011190216057002544,
-0.022483831271529198,
-0.03695220127701759,
-0.03668384253978729,
-0.06320645660161972,
-0.10999823361635208,
0.028258096426725388,
0.024628261104226112,
-0.06239013746380806,
-0.0989660918712616,
0.0058271377347409725,
0.04826178029179573,
0.007091652136296034,
-0.006617661565542221,
-0.010176350362598896,
-0.04996206611394882,
0.051195595413446426,
0.05100112780928612,
0.053923964500427246,
-0.014223682694137096,
0.04464509338140488,
-0.06599778681993484,
7.308650475533847e-36,
0.06001653894782066,
0.03956659138202667,
0.05883651599287987,
0.033156223595142365,
-0.05462665483355522,
-0.02311193011701107,
-0.08563699573278427,
-0.0025375026743859053,
-0.039318520575761795,
-0.00042322761146351695,
-0.06368623673915863,
-0.05830777809023857,
0.02880673296749592,
-0.03535402938723564,
0.06367696076631546,
0.02653472125530243,
0.016588173806667328,
0.04515879228711128,
0.017957670614123344,
-0.05158163607120514,
-0.04619502276182175,
0.1270529180765152,
-0.0615827739238739,
-0.009760265238583088,
-0.02329111658036709,
-0.015013675205409527,
-0.01600123941898346,
0.0293363519012928,
-0.09124363958835602,
0.017039790749549866,
-0.015465217642486095,
-0.006799112539738417,
-0.06512463092803955,
0.02452602982521057,
0.013729644939303398,
0.041933897882699966,
-0.022679781541228294,
-0.00504973204806447,
0.017818517982959747,
-0.017373766750097275,
0.060641318559646606,
-0.004664982669055462,
0.0023676741402596235,
-0.024365877732634544,
0.0372045561671257,
0.06617534160614014,
-0.08319151401519775,
0.03575810045003891,
0.03136678785085678,
0.05007234588265419,
0.013075458817183971,
-0.017086919397115707,
0.08514805883169174,
-0.025278950110077858,
-0.009831307455897331,
0.028437815606594086,
0.0062621766701340675,
0.05898614600300789,
0.08259637653827667,
0.0400332510471344,
-0.03568539768457413,
0.008680946193635464,
0.029135044664144516,
-0.060300007462501526,
-0.015562858432531357,
0.05499648302793503,
-0.08436357229948044,
-0.052410051226615906,
-0.004461879841983318,
0.11192501336336136,
-0.018062649294734,
0.06699727475643158,
0.051840126514434814,
0.06847069412469864,
0.06694117188453674,
0.03516291081905365,
-0.015620702877640724,
-0.08376281708478928,
0.07463593780994415,
0.03922927752137184,
-0.06915169209241867,
-0.008948495611548424,
0.018643369898200035,
-0.07030168175697327,
-0.11299514025449753,
-0.02418251894414425,
0.01926238089799881,
-0.007103771902620792,
0.03896309807896614,
0.05164942890405655,
0.050060518085956573,
-0.020345274358987808,
-0.04448362812399864,
0.02207888849079609,
0.0113094886764884,
-2.0588192134057108e-33,
0.10443145781755447,
-0.048804596066474915,
0.01468148548156023,
-0.052349258214235306,
-0.06288555264472961,
0.04504600539803505,
0.03866398334503174,
0.028468824923038483,
-0.04733424633741379,
0.07448296248912811,
0.08568178862333298,
0.05879933014512062,
-0.056097038090229034,
-0.04020612686872482,
-0.01389460451900959,
0.02446279302239418,
-0.007424483075737953,
0.018945064395666122,
0.12195011973381042,
0.0446384996175766,
-0.10678475350141525,
-0.01919870637357235,
0.005515764933079481,
0.07965850085020065,
-0.019020678475499153,
0.015445117838680744,
-0.0038876719772815704,
-0.030264826491475105,
0.02023432031273842,
0.03200055658817291,
0.03407488018274307,
-0.034365441650152206,
-0.011532599106431007,
0.06586300581693649,
0.028717782348394394,
0.040148284286260605,
-0.059144578874111176,
0.10098914802074432,
-0.05942359194159508,
0.07262241095304489,
-0.12755651772022247,
-0.012459277175366879,
0.001804192434065044,
-0.028313839808106422,
0.07491295784711838,
-0.055892493575811386,
0.010454115457832813,
-0.03495820611715317,
-0.06449593603610992,
-0.09386379271745682,
0.04288674518465996,
0.04200033098459244,
0.023951957002282143,
0.034058164805173874,
0.008498129434883595,
0.10150675475597382,
-0.07183171063661575,
-0.03969947248697281,
0.027670996263623238,
-0.0010698687983676791,
-0.007167476695030928,
-0.01862468384206295,
0.00783778727054596,
-0.03208456188440323,
-0.00017502839909866452,
-0.01444940734654665,
-0.07051324099302292,
0.022519709542393684,
0.012844747863709927,
-0.08819284290075302,
-0.008360404521226883,
-0.09975341707468033,
0.05306176841259003,
0.02644224651157856,
0.0675080418586731,
-0.09571829438209534,
0.04617990180850029,
-0.011745328083634377,
-0.047833070158958435,
-0.04076912999153137,
0.02843143418431282,
-0.01963917165994644,
-0.10942065715789795,
-0.03836565464735031,
-0.12398599088191986,
0.00034972463618032634,
0.058916401118040085,
-0.008552457205951214,
0.05420522391796112,
-0.06573914736509323,
0.06053760275244713,
0.06259243935346603,
-0.03465071693062782,
0.03628619387745857,
0.10900303721427917,
-2.917789032608198e-8,
0.0806243047118187,
-0.05599716678261757,
0.08136260509490967,
-0.05494518205523491,
0.0037711362820118666,
-0.04874776303768158,
-0.02058427222073078,
0.07304049283266068,
0.0070190271362662315,
0.021960606798529625,
-0.0030894484370946884,
0.03733725845813751,
0.040955688804388046,
0.043139081448316574,
0.012315981090068817,
-0.036819592118263245,
-0.08047568798065186,
0.020788738504052162,
-0.010873078368604183,
0.02137869782745838,
0.01772196590900421,
0.03279310464859009,
-0.0279429629445076,
-0.055361680686473846,
0.027767932042479515,
-0.03080303780734539,
-0.005914025008678436,
-0.013552308082580566,
-0.026414215564727783,
0.06046157702803612,
0.0951872318983078,
0.010300235822796822,
-0.025683647021651268,
0.026212038472294807,
0.023558925837278366,
0.10920754075050354,
-0.06408048421144485,
-0.07069956511259079,
-0.04882277920842171,
0.054761145263910294,
-0.03342941775918007,
-0.12318836152553558,
-0.04518282786011696,
0.01582871936261654,
0.007545296102762222,
-0.07374493032693863,
0.033573925495147705,
0.02677430957555771,
0.04811511188745499,
0.05100380256772041,
0.029129590839147568,
-0.03301433101296425,
-0.011117001995444298,
-0.037397291511297226,
-0.030399641022086143,
-0.017444390803575516,
-0.06933695077896118,
0.0007053955923765898,
0.02790394052863121,
-0.11652819067239761,
-0.006948678754270077,
-0.020358126610517502,
0.010285714641213417,
-0.014837383292615414
] |
PMID:21548582 | The design, synthesis, docking, and biological evaluation of novel potent HDAC3 and HDAC8 isoxazole- and pyrazole-based diazide probes suitable for binding ensemble profiling with photoaffinity labeling (BEProFL) experiments in cells is described. | [
-0.019670840352773666,
-0.09350725263357162,
-0.09490160644054413,
0.008716624230146408,
-0.005777799524366856,
-0.005233722738921642,
0.0536908395588398,
0.028829550370573997,
-0.0014084690483286977,
0.047741666436195374,
-0.003642800496891141,
-0.022101087495684624,
0.058724284172058105,
0.1381540149450302,
-0.08910322934389114,
0.07308588176965714,
-0.03211047127842903,
-0.017401747405529022,
0.023912617936730385,
0.03204556182026863,
-0.06100192293524742,
0.001451461692340672,
0.017879856750369072,
0.01664418913424015,
-0.054115477949380875,
0.027471330016851425,
-0.030028466135263443,
0.011914747767150402,
-0.06464521586894989,
-0.028559133410453796,
0.015405656769871712,
-0.005265714135020971,
0.00965699553489685,
-0.043622806668281555,
0.019156431779265404,
-0.022709418088197708,
-0.0663505494594574,
-0.10715949535369873,
-0.014101671986281872,
-0.016100293025374413,
0.004671919625252485,
0.0011153450468555093,
-0.016109619289636612,
-0.002490764716640115,
0.08032958209514618,
-0.10414595901966095,
0.05684636905789375,
-0.02553447149693966,
0.08367562294006348,
-0.019344927743077278,
0.011038616299629211,
0.025597842410206795,
-0.005086502525955439,
0.0423877015709877,
-0.023157669231295586,
0.09227675199508667,
-0.030072081834077835,
-0.022653833031654358,
0.025606222450733185,
-0.0026754415594041348,
-0.041563116014003754,
0.031128685921430588,
-0.006096190772950649,
-0.013740463182330132,
0.04158026725053787,
0.04493341222405434,
-0.04093450307846069,
0.022194860503077507,
0.007578943390399218,
0.01130759995430708,
-0.15375925600528717,
-0.02123415842652321,
0.06760869920253754,
-0.0040053753182291985,
0.10309360176324844,
0.03492513671517372,
0.05095464736223221,
0.043678611516952515,
-0.038830824196338654,
-0.0663309246301651,
0.013481192290782928,
-0.04226546734571457,
0.00024381045659538358,
0.08620291203260422,
0.06656485795974731,
0.10108703374862671,
0.053528741002082825,
0.028340734541416168,
-0.005230458453297615,
-0.10213039815425873,
-0.013958446681499481,
0.06112205982208252,
-0.04299992322921753,
-0.007832542061805725,
-0.07693631201982498,
0.010208262130618095,
0.021589482203125954,
0.0459216944873333,
0.03547774627804756,
0.010601518675684929,
0.06309035420417786,
-0.02930772304534912,
-0.11828058212995529,
-0.03083709627389908,
0.007455240003764629,
-0.00443563936278224,
0.06945623457431793,
0.00511913700029254,
-0.031789038330316544,
-0.053437214344739914,
0.03373175859451294,
-0.002200489630922675,
0.045375559478998184,
0.05400844290852547,
0.002613226417452097,
0.04461067169904709,
0.009058582596480846,
-0.05910205468535423,
-0.0005332946311682463,
-0.014096829108893871,
-0.00880146212875843,
-0.01807594858109951,
0.02413918823003769,
-0.11259789764881134,
0.04405929148197174,
0.03253656253218651,
-0.07204766571521759,
8.715878269969512e-34,
0.05406584218144417,
0.0745004266500473,
0.015854887664318085,
0.06515476107597351,
0.04771995544433594,
-0.030200649052858353,
-0.05229770764708519,
-0.10023072361946106,
-0.09014946967363358,
0.0027303332462906837,
-0.051619116216897964,
0.0639168918132782,
0.05979432165622711,
0.030842052772641182,
0.003078378736972809,
-0.010225992649793625,
-0.04704459011554718,
0.07532954216003418,
-0.023117700591683388,
-0.060964327305555344,
-0.034958820790052414,
0.0048322719521820545,
-0.03975902870297432,
-0.0708542987704277,
0.024312734603881836,
0.04796938970685005,
-0.05881698429584503,
0.07530184090137482,
0.023728029802441597,
-0.027314500883221626,
-0.03132957965135574,
0.03764516860246658,
-0.04876983165740967,
-0.009819809347391129,
0.06222584843635559,
-0.049189627170562744,
0.03548663109540939,
0.009985330514609814,
-0.050441764295101166,
-0.012959521263837814,
0.036280494183301926,
0.05995834991335869,
0.02389042265713215,
0.02461470477283001,
-0.006725717335939407,
-0.024181032553315163,
-0.06433659791946411,
0.10794403403997421,
-0.0008781636715866625,
0.00021686106629204005,
-0.01639055460691452,
-0.12564174830913544,
0.06876518577337265,
0.029994836077094078,
-0.07054658979177475,
0.05949708819389343,
-0.07402445375919342,
-0.015518350526690483,
0.1098095178604126,
-0.0019320063292980194,
-0.062066975980997086,
-0.026321154087781906,
-0.04808921366930008,
0.08075365424156189,
0.032038021832704544,
0.07975905388593674,
-0.07425481826066971,
0.03677670285105705,
0.029050016775727272,
0.09015099704265594,
0.028643183410167694,
0.0394146554172039,
0.036289945244789124,
0.03627625107765198,
0.12340705096721649,
0.025396084412932396,
-0.050703804939985275,
0.026646962389349937,
0.03743452578783035,
0.04805260896682739,
0.04642589017748833,
-0.06115921586751938,
-0.019484316930174828,
0.028306400403380394,
-0.10402658581733704,
-0.08247102797031403,
0.07757474482059479,
-0.0054768407717347145,
-0.035069651901721954,
0.05663132667541504,
0.02605571784079075,
-0.04859213903546333,
0.004289892967790365,
-0.11705947667360306,
-0.05182400718331337,
-1.0704656754507431e-33,
0.09667841345071793,
-0.0014834385365247726,
-0.004148304928094149,
-0.047295473515987396,
0.08247970789670944,
-0.018393583595752716,
0.047568000853061676,
-0.06147349998354912,
0.05940694361925125,
-0.03390171006321907,
0.14762072265148163,
0.037310827523469925,
0.009236384183168411,
-0.01748403161764145,
-0.07111024856567383,
0.02602461539208889,
-0.022288642823696136,
-0.09493225812911987,
0.015264727175235748,
0.0035648802295327187,
-0.05213569849729538,
-0.09177906066179276,
0.04422727972269058,
0.044193439185619354,
-0.044561609625816345,
0.010202188044786453,
0.08088819682598114,
-0.0027070457581430674,
-0.01342557929456234,
0.024400966241955757,
-0.025506895035505295,
0.00032610251219011843,
-0.049186136573553085,
-0.059547267854213715,
0.025862684473395348,
0.05243619158864021,
0.019379734992980957,
-0.06495007872581482,
0.011845583096146584,
-0.020598553121089935,
-0.008961308747529984,
-0.03102266974747181,
-0.08999206870794296,
-0.0018267275299876928,
0.03257478028535843,
0.09049379825592041,
-0.07319027930498123,
0.022301366552710533,
-0.015661494806408882,
-0.009420657530426979,
-0.011354459449648857,
-0.012650365941226482,
-0.022403322160243988,
0.0436711311340332,
0.00947109516710043,
-0.003917001187801361,
0.06457601487636566,
-0.0021098246797919273,
0.06182163953781128,
0.043429963290691376,
0.012312802486121655,
0.011772384867072105,
0.010760611854493618,
-0.02661876566708088,
-0.03359270095825195,
-0.012298298999667168,
0.014185648411512375,
0.03046175092458725,
0.06983544677495956,
0.025809599086642265,
0.07581620663404465,
-0.04844598472118378,
0.10216125100851059,
0.11617466062307358,
-0.011745116673409939,
-0.002279696287587285,
-0.04930427297949791,
-0.03519674018025398,
0.046876952052116394,
0.04022367671132088,
0.09984889626502991,
-0.07303337752819061,
-0.029285486787557602,
0.0193743035197258,
0.01959749311208725,
0.019372178241610527,
0.020734073594212532,
0.001885546138510108,
-0.027821090072393417,
-0.04627377167344093,
0.08644024282693863,
-0.04109175130724907,
-0.005725597031414509,
0.02801675535738468,
0.02581200562417507,
-3.03063529827341e-8,
0.047217052429914474,
-0.0967651829123497,
0.004636912606656551,
-0.05904148519039154,
-0.1231980100274086,
0.03606649860739708,
-0.0073113515973091125,
0.014822232536971569,
0.05907054618000984,
-0.02608611062169075,
0.10237082839012146,
-0.046524085104465485,
-0.03975733369588852,
0.006661009043455124,
-0.025131860747933388,
0.05266782268881798,
0.0384274423122406,
-0.01649174466729164,
-0.05249416083097458,
0.0031362702138721943,
-0.13667680323123932,
0.03844393417239189,
-0.03727554902434349,
-0.07770222425460815,
0.09576302021741867,
-0.04650243744254112,
-0.013526201248168945,
-0.0562688447535038,
0.021482286974787712,
-0.07215116918087006,
0.06488699465990067,
0.001216157921589911,
0.025974130257964134,
0.006664311047643423,
-0.00889802910387516,
0.03738188371062279,
-0.07229262590408325,
-0.010502535849809647,
-0.010293965227901936,
0.09467753767967224,
-0.013761329464614391,
0.0020819194614887238,
-0.11533135175704956,
-0.09043198078870773,
-0.04024507477879524,
-0.027699803933501244,
-0.0064740595407783985,
0.054804056882858276,
-0.02405640482902527,
-0.02011188305914402,
-0.03172425553202629,
-0.03557523339986801,
0.02519472874701023,
-0.09970927983522415,
-0.025744285434484482,
-0.016867652535438538,
0.03363519906997681,
0.011111916974186897,
0.0366654247045517,
-0.006805917248129845,
-0.0006034414400346577,
-0.008590231649577618,
-0.000992773100733757,
0.021313726902008057
] |
PMID:21548582 | Both the isoxazole- and pyrazole-based probes exhibit low nanomolar inhibitory activity against HDAC3 and HDAC8, respectively. | [
0.0368209108710289,
-0.10105344653129578,
-0.03451942652463913,
0.010207396931946278,
0.0567794106900692,
-0.05585331469774246,
0.0005373708554543555,
-0.018796691671013832,
-0.029785988852381706,
0.06451252847909927,
0.02149697206914425,
0.048864394426345825,
-0.03662639483809471,
0.0869990661740303,
-0.0010956339538097382,
0.07842914760112762,
-0.006303069181740284,
0.020960094407200813,
0.04808199405670166,
0.0680483728647232,
-0.007047742605209351,
-0.03266808018088341,
0.05850692465901375,
0.08133025467395782,
-0.09534136950969696,
0.007800857070833445,
0.01886422373354435,
0.045051295310258865,
-0.08042200654745102,
-0.028243962675333023,
-0.0528973825275898,
-0.019545406103134155,
0.04322807490825653,
-0.01412837766110897,
0.0150496456772089,
-0.02142270654439926,
-0.09922326356172562,
0.012969177216291428,
-0.07789339870214462,
-0.08563420176506042,
0.04879303649067879,
-0.05737276002764702,
0.004881500732153654,
-0.005818805191665888,
0.04657274857163429,
-0.18023334443569183,
0.03803778812289238,
-0.09467867016792297,
0.12884065508842468,
0.06865955144166946,
-0.02859962172806263,
0.011506997048854828,
-0.0008339714258909225,
-0.0036245081573724747,
-0.020492548123002052,
0.032379474490880966,
0.012620567344129086,
0.014474327675998211,
0.0813792273402214,
-0.05888528749346733,
-0.041665684431791306,
-0.0003279554075561464,
0.01110733114182949,
0.0038129547610878944,
-0.021294280886650085,
0.003287737024948001,
0.012267320416867733,
-0.00885045062750578,
0.0061560338363051414,
0.051444683223962784,
-0.09091459959745407,
-0.061757031828165054,
-0.02429165504872799,
0.056655168533325195,
0.08087333291769028,
0.0021133983973413706,
0.05508093163371086,
-0.03262285515666008,
0.016652347519993782,
0.00885083433240652,
-0.026852669194340706,
-0.03538969159126282,
0.01261923462152481,
0.15496839582920074,
-0.03867696598172188,
0.11018726229667664,
0.05115767940878868,
-0.03162069618701935,
0.04284469038248062,
-0.09548044204711914,
0.008915890008211136,
0.08186709880828857,
-0.029698651283979416,
0.020499009639024734,
-0.02914721518754959,
0.000991698238067329,
0.023628856986761093,
0.06422486156225204,
-0.022284138947725296,
0.0010260030394420028,
0.12367578595876694,
-0.027576453983783722,
-0.17027071118354797,
-0.013595246709883213,
-0.04920761659741402,
0.03185364603996277,
0.02328995056450367,
-0.03456580266356468,
-0.046503838151693344,
0.01172214187681675,
-0.08177526295185089,
0.008490245789289474,
0.02066187933087349,
0.029102327302098274,
-0.0914841741323471,
-0.030201418325304985,
0.0835120752453804,
-0.027417844161391258,
-0.04555724933743477,
-0.005693539511412382,
0.007175460923463106,
-0.04652102664113045,
0.07153584063053131,
-0.10612927377223969,
0.05688442289829254,
0.005246199667453766,
-0.036425549536943436,
-6.792419618783888e-34,
-0.027994992211461067,
0.04312426596879959,
-0.010286660864949226,
-0.01105792447924614,
0.03489202260971069,
-0.08032286912202835,
-0.020725471898913383,
0.00909637100994587,
-0.03358203172683716,
0.011453515850007534,
-0.0460304394364357,
0.0499744713306427,
0.05385932698845863,
0.02023318037390709,
-0.02381746657192707,
0.025215519592165947,
0.060148078948259354,
-0.0014113358920440078,
0.0005131084471940994,
-0.05434747412800789,
-0.010558350011706352,
0.01353906374424696,
-0.014758368954062462,
-0.05165977030992508,
-0.0100576626136899,
-0.025945251807570457,
-0.04771888256072998,
0.09691959619522095,
0.015106326900422573,
-0.023072924464941025,
-0.05857716128230095,
0.021263355389237404,
-0.054402776062488556,
-0.03297201916575432,
0.13051992654800415,
-0.0002969335182569921,
-0.047916099429130554,
0.0037347706966102123,
-0.01317245326936245,
-0.01015566848218441,
-0.0034292861819267273,
0.043309688568115234,
0.02004333958029747,
-0.02685430459678173,
0.04930974543094635,
-0.05072791501879692,
-0.09180165082216263,
0.06933829933404922,
-0.03601924329996109,
0.03126305714249611,
0.0434330552816391,
-0.07990755140781403,
0.042705245316028595,
0.04422128573060036,
0.027588795870542526,
0.03662508353590965,
-0.034492556005716324,
-0.05537720397114754,
0.07581289857625961,
0.01174111757427454,
-0.03889869898557663,
-0.03552069514989853,
-0.017967531457543373,
0.0793277844786644,
-0.02049964852631092,
0.06890247762203217,
-0.02926502376794815,
0.0032151772174984217,
-0.006968789733946323,
-0.0026715253479778767,
0.030328981578350067,
0.03062460571527481,
-0.0006338323000818491,
0.05347383767366409,
0.036795079708099365,
0.017852850258350372,
-0.07445578277111053,
0.03338884189724922,
0.10867730528116226,
0.014273148030042648,
0.039299044758081436,
-0.07441675662994385,
0.06348686665296555,
0.026545941829681396,
-0.09464042633771896,
-0.04963763430714607,
-0.01606917567551136,
0.014126982539892197,
-0.010646386072039604,
-0.0281582772731781,
0.07680383324623108,
-0.07177241891622543,
-0.026726454496383667,
-0.062406137585639954,
-0.0012129133101552725,
-8.82424323708098e-34,
0.058450330048799515,
-0.001964837545529008,
0.03985080495476723,
-0.06703644245862961,
0.08009913563728333,
-0.041892558336257935,
0.05137082189321518,
-0.05844579264521599,
0.035633284598588943,
-0.030968880280852318,
0.1399620920419693,
-0.01683833636343479,
0.006310027092695236,
-0.061147864907979965,
0.00777457794174552,
0.05656231939792633,
-0.00008430277375737205,
-0.0799383670091629,
-0.010214530862867832,
-0.005497410893440247,
-0.042714349925518036,
0.008227634243667126,
0.04637822136282921,
0.028788484632968903,
-0.043445151299238205,
-0.040928538888692856,
0.045328427106142044,
0.04271109029650688,
0.04066184163093567,
0.04821434244513512,
-0.03140535578131676,
0.0724584311246872,
-0.023232638835906982,
-0.05176815018057823,
0.07894603908061981,
0.030736884102225304,
0.021618518978357315,
-0.03450677543878555,
-0.035047657787799835,
-0.030524617061018944,
0.026794850826263428,
0.03299850970506668,
-0.016972271725535393,
-0.008602595888078213,
-0.0030101779848337173,
0.15020427107810974,
-0.036499615758657455,
0.02609092928469181,
-0.07772041857242584,
-0.01688130386173725,
0.04074807092547417,
-0.006491132080554962,
0.01545332558453083,
0.0028559600468724966,
0.06659822911024094,
0.02464475855231285,
0.010417790152132511,
0.05547191575169563,
0.054746903479099274,
0.005760901141911745,
-0.021629763767123222,
0.016575803980231285,
-0.0196586512029171,
0.03384726867079735,
-0.04651571065187454,
0.027559680864214897,
-0.032096631824970245,
0.03189026191830635,
0.023093970492482185,
-0.05091487243771553,
0.0762413889169693,
0.021726135164499283,
0.04883279278874397,
0.05751313269138336,
-0.07524112612009048,
0.04384835809469223,
-0.03706783801317215,
-0.04050377756357193,
0.02523338422179222,
0.04606575891375542,
0.08853642642498016,
0.026979079470038414,
0.027452178299427032,
0.052845679223537445,
-0.047703828662633896,
0.00010413871495984495,
-0.05410004034638405,
-0.04126887768507004,
-0.09480736404657364,
0.025231510400772095,
0.055709172040224075,
-0.0610833503305912,
0.009732355363667011,
0.07364609837532043,
0.02223675698041916,
-2.493861472885328e-8,
0.016925431787967682,
-0.040220052003860474,
-0.022748081013560295,
-0.1346530169248581,
-0.08196799457073212,
-0.004169393330812454,
-0.0761118084192276,
0.056498926132917404,
0.06168172508478165,
-0.020502528175711632,
0.05312344431877136,
0.041875019669532776,
0.014033191837370396,
0.033804167062044144,
-0.04460766166448593,
0.011276591569185257,
0.05058567598462105,
0.000786007207352668,
-0.029699712991714478,
-0.05769294872879982,
-0.06272216141223907,
0.09549302607774734,
-0.08428442478179932,
-0.03211939334869385,
0.08622794598340988,
-0.01680055633187294,
0.00006932544783921912,
-0.05019145458936691,
-0.030254030600190163,
-0.10651195049285889,
0.0020663125906139612,
-0.025903038680553436,
0.022510919719934464,
0.025053612887859344,
-0.00909655261784792,
0.10344664007425308,
-0.004973734263330698,
-0.04905242845416069,
-0.0025963967200368643,
0.021273313090205193,
0.018902547657489777,
-0.033502187579870224,
-0.06624927371740341,
-0.07185763120651245,
-0.08752309530973434,
-0.06480103731155396,
-0.018428975716233253,
0.05398205667734146,
-0.05007439851760864,
-0.05730336159467697,
0.04114801436662674,
-0.011407379992306232,
-0.0066725206561386585,
-0.1411120891571045,
-0.015202601440250874,
-0.04999130219221115,
0.019200412556529045,
-0.0008622999303042889,
-0.019493823871016502,
0.025184528902173042,
0.0679144635796547,
-0.062210872769355774,
0.03309696912765503,
-0.005714049097150564
] |
PMID:21548582 | The pyrazole-based probe 3f appears to be one of the most active HDAC8 inhibitors reported in the literature with an IC(50) of 17 nM. | [
0.022584307938814163,
-0.07220710813999176,
-0.060226354748010635,
-0.011464577168226242,
0.050898998975753784,
-0.051826681941747665,
-0.014683658257126808,
0.018614692613482475,
-0.041365258395671844,
0.06289610266685486,
-0.023970231413841248,
0.027692612260580063,
-0.04552711173892021,
0.11316857486963272,
-0.01985914073884487,
0.05600724369287491,
-0.03057027794420719,
-0.04053889214992523,
0.017079489305615425,
0.02982456609606743,
-0.030256647616624832,
0.00023550467449240386,
0.07463426142930984,
0.07342685014009476,
-0.10222559422254562,
0.012249056249856949,
0.023602640256285667,
0.047050654888153076,
-0.11604524403810501,
-0.011153405532240868,
-0.03470027446746826,
0.025980249047279358,
0.01194698829203844,
-0.021545113995671272,
-0.011373911052942276,
-0.017411556094884872,
-0.12853701412677765,
-0.033156104385852814,
-0.06500314176082611,
-0.046290189027786255,
0.04646310955286026,
-0.06494729965925217,
0.0200389064848423,
-0.027758745476603508,
0.070761539041996,
-0.12679609656333923,
-0.0028411278035491705,
-0.06932912021875381,
0.16898781061172485,
0.0792207419872284,
-0.021646663546562195,
-0.0021212485153228045,
-0.02421276830136776,
0.04377969726920128,
-0.024986151605844498,
0.04687729477882385,
-0.00804075226187706,
0.015458845533430576,
0.06569679826498032,
-0.023420019075274467,
-0.03499559685587883,
0.010495892725884914,
0.018301814794540405,
0.009256716817617416,
0.04622765630483627,
0.020249653607606888,
0.01020288746803999,
-0.08323898911476135,
-0.012728231959044933,
0.05806736648082733,
-0.07010926306247711,
-0.043163493275642395,
-0.04329982399940491,
0.027999335899949074,
0.11447052657604218,
-0.004208109807223082,
0.06266921758651733,
-0.018422020599246025,
0.008822401985526085,
-0.05665217712521553,
0.02570977434515953,
-0.020802762359380722,
0.03989935293793678,
0.1261056661605835,
-0.024168426170945168,
0.047019112855196,
0.0062292711809277534,
-0.009423933923244476,
0.041752368211746216,
-0.07230670005083084,
0.023131487891077995,
0.0774884819984436,
-0.06556102633476257,
0.016451450064778328,
-0.01718529313802719,
0.016337258741259575,
0.00629728427156806,
0.0460057333111763,
-0.05003086104989052,
0.020562253892421722,
0.08115701377391815,
-0.03999299556016922,
-0.14300066232681274,
0.014085975475609303,
-0.06921295076608658,
0.06106122210621834,
0.03823830187320709,
0.010236505419015884,
-0.09874215722084045,
-0.022507039830088615,
-0.05705510824918747,
0.0029781716875731945,
0.0302595105022192,
0.0033199514728039503,
-0.012305248528718948,
-0.010712570510804653,
0.044193752110004425,
-0.028046593070030212,
0.013279665261507034,
-0.007266077678650618,
0.012795710936188698,
-0.031616032123565674,
0.07979051023721695,
-0.09687415510416031,
0.011919677257537842,
0.023862916976213455,
-0.07374307513237,
-1.1753916787375829e-33,
-0.004011393990367651,
0.08316226303577423,
0.007839473895728588,
-0.003562891623005271,
0.046359699219465256,
-0.08795332163572311,
-0.03495166450738907,
-0.03914129361510277,
-0.019106557592749596,
0.027294287458062172,
-0.015475536696612835,
0.02744506113231182,
0.06800907105207443,
-0.0038451242726296186,
-0.056012365967035294,
-0.002217778703197837,
0.05379630997776985,
0.04840134456753731,
-0.027886109426617622,
-0.059548091143369675,
0.033149346709251404,
0.034867171198129654,
-0.008479381911456585,
-0.056125424802303314,
0.03065524250268936,
0.02198708988726139,
-0.03134435787796974,
0.12151558697223663,
0.052086956799030304,
-0.021478867158293724,
-0.02854016050696373,
-0.0015943121397867799,
-0.09066669642925262,
-0.047332532703876495,
0.06995198875665665,
-0.04341161251068115,
-0.07100233435630798,
-0.031339336186647415,
-0.02925966866314411,
0.035919662564992905,
0.047620177268981934,
0.035855431109666824,
0.026226656511425972,
-0.004699249751865864,
0.04705185815691948,
-0.019214993342757225,
-0.11908367276191711,
0.043080683797597885,
-0.005636575166136026,
0.06647299230098724,
0.06661399453878403,
-0.08545497059822083,
0.02319980412721634,
0.07424890249967575,
-0.0047785211354494095,
0.011403892189264297,
-0.04327511787414551,
-0.0312526635825634,
0.10851629078388214,
0.011057570576667786,
0.0044945175759494305,
-0.05351622402667999,
-0.034437395632267,
0.04813477769494057,
-0.02272139862179756,
0.06151778995990753,
-0.025462228804826736,
-0.04192974418401718,
0.0007822446641512215,
-0.007833951152861118,
0.014163612388074398,
0.013094866648316383,
0.015055176801979542,
0.03631362318992615,
0.08799087256193161,
-0.011973850429058075,
-0.06890836358070374,
0.029141666367650032,
0.05481499806046486,
-0.00898385513573885,
0.007391408551484346,
-0.06413809955120087,
0.04939648509025574,
0.07030073553323746,
-0.08147270977497101,
-0.06811567395925522,
-0.0047136591747403145,
-0.028179559856653214,
-0.029635850340127945,
-0.04859622195363045,
0.044527724385261536,
-0.06095201522111893,
-0.017570409923791885,
-0.05040392652153969,
0.01725941337645054,
1.6849996350111161e-34,
0.041475459933280945,
-0.007580831181257963,
0.050039567053318024,
-0.05552962049841881,
0.08417771756649017,
-0.029305770993232727,
0.06647384911775589,
-0.06747258454561234,
0.07886437326669693,
-0.03362143039703369,
0.16724619269371033,
-0.029469190165400505,
0.0008892532787285745,
-0.11563592404127121,
0.04684078320860863,
0.053567495197057724,
0.007092244457453489,
-0.08262553811073303,
0.005781751591712236,
0.012771525420248508,
0.018332816660404205,
-0.005681679118424654,
0.039475005120038986,
0.060820743441581726,
-0.02636234275996685,
-0.0692223533987999,
0.06737761199474335,
0.015731021761894226,
0.0645977035164833,
0.053107310086488724,
-0.031758200377225876,
0.05439171940088272,
-0.03671567514538765,
-0.003513085190206766,
0.048202306032180786,
0.018171465024352074,
0.04121548682451248,
-0.0468420647084713,
-0.021054718643426895,
-0.027827076613903046,
0.029033005237579346,
0.035922806710004807,
-0.013707215897738934,
0.03575803339481354,
-0.025125740095973015,
0.16942483186721802,
-0.009644736535847187,
0.048964954912662506,
-0.016098568215966225,
0.005484868306666613,
0.01798381097614765,
-0.03388708829879761,
0.021629653871059418,
-0.012118917889893055,
0.07096882164478302,
0.021325938403606415,
0.03950735554099083,
0.023889640346169472,
0.053516846150159836,
-0.0016669788165017962,
0.020344922319054604,
0.032446663826704025,
-0.005411098711192608,
0.010083060711622238,
0.002822465030476451,
0.06762946397066116,
-0.041022539138793945,
0.03392855450510979,
0.04128212481737137,
-0.04162301495671272,
0.0834536924958229,
-0.040102895349264145,
0.035175442695617676,
0.0932839885354042,
-0.03580489382147789,
-0.01667945459485054,
-0.022395392879843712,
-0.03347638621926308,
0.05352729558944702,
0.07088488340377808,
0.07401116192340851,
-0.016193047165870667,
0.023077217862010002,
0.032975614070892334,
-0.015203519724309444,
-0.07942026108503342,
0.010886193253099918,
-0.03786412253975868,
-0.08744026720523834,
-0.01578296720981598,
0.05656632408499718,
-0.0712999701499939,
-0.028685133904218674,
0.0810001939535141,
0.03180364891886711,
-2.6032962452404718e-8,
0.06501919776201248,
-0.05919857695698738,
-0.029427317902445793,
-0.10735224932432175,
-0.050166793167591095,
-0.03520916774868965,
-0.05195418745279312,
0.058464307337999344,
0.04823267087340355,
-0.02660282514989376,
0.059242814779281616,
0.02458120696246624,
0.030396718531847,
0.021605342626571655,
-0.04145209863781929,
-0.02731930837035179,
0.05907433107495308,
0.02836615778505802,
-0.03393939509987831,
-0.0480586402118206,
-0.03999627009034157,
0.08314516395330429,
-0.061331287026405334,
-0.10154347121715546,
0.0697249248623848,
0.02448027953505516,
-0.04974546656012535,
-0.03153841570019722,
-0.04336719214916229,
-0.0941937193274498,
0.007850990630686283,
-0.02190738171339035,
0.05448636785149574,
0.016324222087860107,
0.007311565801501274,
0.09054367244243622,
-0.037911392748355865,
-0.033125922083854675,
0.010482456535100937,
0.04519245773553848,
0.008624915033578873,
-0.03371186926960945,
-0.02679396979510784,
-0.06754492968320847,
-0.08110000938177109,
-0.042981576174497604,
-0.028960801661014557,
0.036294758319854736,
-0.04713016375899315,
-0.08874296396970749,
0.033931147307157516,
0.03388815000653267,
-0.006208142731338739,
-0.126638725399971,
-0.05697576701641083,
-0.03481180965900421,
0.007850105874240398,
-0.006437345873564482,
-0.0038797082379460335,
-0.017816996201872826,
0.06894902884960175,
-0.07360322773456573,
0.012591575272381306,
-0.03471044450998306
] |
PMID:21548582 | Our docking studies suggest that unlike the isoxazole-based ligands the pyrazole-based ligands are flexible enough to occupy the second binding site of HDAC8. | [
-0.02932353876531124,
-0.0712534487247467,
-0.07391089200973511,
-0.015508093871176243,
-0.01697808876633644,
-0.0349617600440979,
0.009271068498492241,
0.05903107672929764,
-0.017942503094673157,
0.016349008306860924,
-0.004926652181893587,
0.056789226830005646,
-0.03850678354501724,
0.09423568844795227,
0.00643668370321393,
0.05379091203212738,
-0.05256362631917,
-0.014639312401413918,
-0.0014512483030557632,
0.12154050916433334,
-0.008204523473978043,
-0.03729015216231346,
0.010343178175389767,
0.042274896055459976,
-0.08739854395389557,
0.055197544395923615,
0.055857207626104355,
0.06912937015295029,
-0.03421283885836601,
-0.08783488720655441,
-0.023897800594568253,
0.012507636100053787,
-0.002819300629198551,
-0.03716680034995079,
-0.024490362033247948,
0.0003044585173483938,
-0.03350412845611572,
-0.017366208136081696,
-0.04783939570188522,
-0.07820453494787216,
0.07690361887216568,
-0.024159301072359085,
0.05526082217693329,
-0.0007896120660007,
0.02348385378718376,
-0.17458076775074005,
0.030889423564076424,
-0.037749942392110825,
0.095106340944767,
0.07269090414047241,
-0.010682972148060799,
-0.014459344558417797,
-0.006688018329441547,
0.027675922960042953,
-0.033944182097911835,
0.08486732840538025,
0.01965569704771042,
0.014524565078318119,
0.06932763010263443,
-0.04365042969584465,
0.031330738216638565,
-0.011298935860395432,
0.01840180531144142,
0.03605792298913002,
-0.006509342230856419,
-0.023135341703891754,
0.04550716280937195,
-0.03366934135556221,
-0.02589893899857998,
0.04370797052979469,
-0.09313000738620758,
-0.037707868963479996,
-0.10545557737350464,
0.006755088921636343,
0.10715272277593613,
0.018235020339488983,
0.0067819030955433846,
-0.0446024015545845,
-0.004849858116358519,
-0.015269273892045021,
0.0028825656045228243,
0.054954059422016144,
0.01861199177801609,
0.09096841514110565,
-0.031043624505400658,
0.027227623388171196,
-0.0011819630162790418,
0.029458703473210335,
0.019518384709954262,
-0.13342398405075073,
0.0735320970416069,
0.06323948502540588,
-0.041794586926698685,
-0.012550375424325466,
-0.03978739678859711,
-0.012563265860080719,
0.03444785624742508,
0.10635311901569366,
-0.025820141658186913,
-0.009636888280510902,
0.08077066391706467,
-0.01470041275024414,
-0.14200785756111145,
0.008091933093965054,
-0.004031656309962273,
0.019882483407855034,
0.010161417536437511,
-0.029084373265504837,
-0.09713573753833771,
-0.04521232843399048,
-0.08245916664600372,
-0.01483894046396017,
0.10098041594028473,
0.02806275524199009,
-0.060155585408210754,
0.04663438722491264,
-0.014629561454057693,
-0.02803664468228817,
0.0040689692832529545,
-0.022744232788681984,
-0.02623630128800869,
0.0032757832668721676,
0.09281222522258759,
-0.07549180090427399,
0.04217701032757759,
-0.008154645562171936,
-0.12442880123853683,
-7.128688489318946e-35,
0.0038653474766761065,
0.04411596059799194,
0.01928037777543068,
0.017496382817626,
0.07412958890199661,
-0.12198829650878906,
-0.031353387981653214,
-0.059182435274124146,
-0.07800319045782089,
0.032273367047309875,
-0.029413092881441116,
0.06248508766293526,
0.06374771893024445,
-0.022616254165768623,
-0.04842047020792961,
0.008127433247864246,
0.04600132629275322,
0.09416831284761429,
-0.0307381059974432,
-0.03671251982450485,
-0.026385752484202385,
0.07320694625377655,
0.005903735291212797,
-0.06593629717826843,
0.042072080075740814,
0.05996811017394066,
0.009530392475426197,
0.1027129739522934,
0.02620472013950348,
-0.013606468215584755,
-0.012615642510354519,
0.01746785081923008,
-0.10198128968477249,
-0.02051101252436638,
0.12737269699573517,
-0.015127868391573429,
-0.031880803406238556,
0.003762876382097602,
-0.04677979648113251,
-0.03640410676598549,
0.027285022661089897,
0.033852752298116684,
0.004419454839080572,
0.029092857614159584,
0.04678906872868538,
-0.043246522545814514,
-0.04036600515246391,
0.06422482430934906,
-0.03391561657190323,
0.01134549081325531,
0.02111562341451645,
-0.055465515702962875,
-0.010380526073276997,
0.05489087477326393,
-0.03411521762609482,
0.0116066113114357,
-0.06329736113548279,
-0.04242762178182602,
0.04386216402053833,
0.030441639944911003,
-0.030626021325588226,
-0.02156328782439232,
-0.04481371119618416,
0.01760895922780037,
0.01877283677458763,
0.08421047776937485,
-0.03388780727982521,
-0.03383861109614372,
0.04283546656370163,
0.030486734583973885,
0.07275720685720444,
0.0265668835490942,
0.016224563121795654,
0.05659671500325203,
0.0627334713935852,
-0.0076665375381708145,
-0.05960801616311073,
-0.05303395539522171,
0.07932081818580627,
0.01605246216058731,
-0.035100057721138,
-0.05033927038311958,
-0.0004180351388640702,
0.04415786266326904,
-0.07631520926952362,
-0.1294502466917038,
0.0564495325088501,
0.00756782665848732,
-0.0594116635620594,
-0.040191665291786194,
0.00906994566321373,
-0.0698239728808403,
0.015257928520441055,
-0.12131807208061218,
0.008317667059600353,
-1.456442000608126e-33,
0.03816274181008339,
-0.025244858115911484,
0.04160312935709953,
-0.06216864287853241,
0.08055062592029572,
-0.0251177828758955,
0.04673635959625244,
-0.0779637023806572,
0.023542897775769234,
-0.035180315375328064,
0.1543450504541397,
0.03284798562526703,
0.008666850626468658,
-0.020650891587138176,
0.018351146951317787,
0.04222423955798149,
-0.022930501028895378,
-0.05081288516521454,
0.007961987517774105,
-0.024792779237031937,
0.03468320891261101,
-0.046107858419418335,
0.0073645394295454025,
0.09124147891998291,
-0.027076411992311478,
-0.07145067304372787,
0.09756000339984894,
0.013821233995258808,
0.06702936440706253,
0.08525583148002625,
-0.043094467371702194,
0.047531526535749435,
-0.10687299072742462,
-0.02867788076400757,
0.030792003497481346,
0.011669342406094074,
-0.054751206189394,
-0.01725221797823906,
0.0028875325806438923,
-0.07114008069038391,
0.004325120244175196,
0.007712044287472963,
-0.04357700049877167,
0.013335295021533966,
0.026699351146817207,
0.0765334889292717,
-0.03966865688562393,
0.0798787772655487,
-0.08123887330293655,
-0.041987575590610504,
0.025734249502420425,
-0.04144053906202316,
0.05353933200240135,
-0.027056289836764336,
0.060262393206357956,
0.051064640283584595,
0.031536661088466644,
0.013908186927437782,
0.0352657325565815,
-0.01469396147876978,
0.00020476846839301288,
0.041562654078006744,
-0.01669725775718689,
0.026192890480160713,
-0.020841166377067566,
0.020279718562960625,
-0.02070699632167816,
-0.05215098336338997,
-0.03439834341406822,
-0.022154800593852997,
0.10962560027837753,
-0.06483463197946548,
0.05368759483098984,
0.12217085808515549,
-0.002916002878919244,
0.014413959346711636,
0.016196386888623238,
-0.04776296019554138,
0.07066110521554947,
0.031126854941248894,
0.016229551285505295,
-0.03089466504752636,
0.06896450370550156,
-0.017109178006649017,
-0.013627691194415092,
-0.0034221934620290995,
0.020268240943551064,
-0.017480261623859406,
-0.03016236051917076,
0.03973308950662613,
0.04194403067231178,
-0.031113428995013237,
-0.004669851623475552,
0.10540105402469635,
0.04272456839680672,
-2.484508598854518e-8,
0.06644228845834732,
-0.04116050899028778,
0.006022715475410223,
-0.09184481203556061,
-0.09680494666099548,
0.022033674642443657,
-0.05975721403956413,
0.027269216254353523,
0.06115579232573509,
0.005281296093016863,
0.046421341598033905,
0.00109951407648623,
-0.001514545874670148,
0.05564200133085251,
-0.022440917789936066,
0.0766553059220314,
0.024792876094579697,
-0.013630255125463009,
-0.048810023814439774,
-0.048134662210941315,
-0.06861317902803421,
0.07284080237150192,
-0.022243918851017952,
-0.06506115198135376,
0.0522925890982151,
-0.03279011324048042,
-0.0662192553281784,
-0.016742056235671043,
-0.03124232590198517,
-0.06069130077958107,
0.05925378575921059,
-0.0012006870238110423,
-0.006956661120057106,
0.02624420076608658,
0.020094864070415497,
0.021040940657258034,
-0.029560767114162445,
-0.04200267791748047,
0.03246931731700897,
0.022727642208337784,
0.037130311131477356,
-0.10638163983821869,
-0.03932560607790947,
-0.0812545120716095,
-0.006869095377624035,
0.02011389099061489,
0.009885533712804317,
0.07472095638513565,
-0.028920693323016167,
0.009763737209141254,
0.004357393365353346,
-0.010287703014910221,
-0.018110420554876328,
-0.1493987888097763,
0.010856096632778645,
0.010696370154619217,
-0.0061246128752827644,
0.0487084835767746,
0.013059942051768303,
0.008333546109497547,
0.01261865347623825,
-0.020186875015497208,
0.0425100140273571,
-0.03386354818940163
] |
PMID:21548582 | Probes/inhibitors 2b, 3a, 3c, and 3f exerted the antiproliferative and neuroprotective activities at micromolar concentrations through inhibition of nuclear HDACs, indicating that they are cell permeable and the presence of an azide or a diazide group does not interfere with the neuroprotection properties, or enhance cellular cytotoxicity, or affect cell permeability. | [
-0.01585300825536251,
-0.09926071763038635,
-0.09722684323787689,
0.020785432308912277,
0.06353352963924408,
0.05065406486392021,
0.05047404766082764,
0.04458236321806908,
0.02166261337697506,
0.08586376905441284,
-0.010733536444604397,
-0.011565071530640125,
0.054387107491493225,
0.07240943610668182,
-0.0824199840426445,
0.06022335961461067,
-0.05125245451927185,
0.03127046674489975,
-0.005500836297869682,
0.04022274538874626,
-0.034110669046640396,
0.017852799966931343,
0.04271519556641579,
0.06672585755586624,
-0.09377307444810867,
0.0114933205768466,
-0.018504099920392036,
0.023687977343797684,
-0.04261200875043869,
0.0016411738470196724,
0.004741481505334377,
-0.01450592651963234,
0.02337878942489624,
-0.040252987295389175,
0.08589661866426468,
-0.042884789407253265,
-0.15766490995883942,
-0.07131719589233398,
-0.0956193059682846,
-0.006030806340277195,
0.04965430870652199,
-0.022881528362631798,
-0.039890676736831665,
0.03032786212861538,
0.05010123550891876,
-0.07619425654411316,
-0.0066229538060724735,
-0.06750231236219406,
0.04722131788730621,
0.01759580336511135,
0.021073127165436745,
-0.020249320194125175,
-0.026689672842621803,
0.09480148553848267,
0.0020798195619136095,
0.037420738488435745,
-0.08156556636095047,
0.0578065849840641,
-0.02981552481651306,
0.09465359896421432,
-0.019260751083493233,
0.014897036366164684,
0.04435199499130249,
-0.032115090638399124,
0.10750354081392288,
0.07691560685634613,
-0.09282597154378891,
-0.045373305678367615,
-0.016590291634202003,
0.027000579982995987,
-0.016649477183818817,
-0.06967698037624359,
-0.0008731085690669715,
-0.04969730228185654,
0.08007360994815826,
-0.05991262570023537,
0.010318480432033539,
0.0014016160275787115,
-0.033704329282045364,
-0.10678655654191971,
0.00719293300062418,
-0.0623897984623909,
0.07066193968057632,
0.1565229892730713,
0.046461090445518494,
0.11294466257095337,
0.007686557248234749,
-0.054318737238645554,
0.04198519513010979,
0.06469456106424332,
0.0037842898163944483,
-0.021295594051480293,
-0.0231429822742939,
0.011035474017262459,
-0.0245415810495615,
-0.06939525902271271,
-0.04280745983123779,
-0.010609685443341732,
0.00587861891835928,
0.0033893513027578592,
0.11619450151920319,
-0.004429762717336416,
-0.09889248013496399,
-0.045033048838377,
-0.04899262636899948,
0.036410603672266006,
0.04115094244480133,
-0.04573636129498482,
-0.07884050160646439,
0.03590812161564827,
0.02084125578403473,
0.03989700600504875,
0.021822625771164894,
-0.015078553929924965,
-0.06386113166809082,
0.026448896154761314,
0.11555111408233643,
-0.007819496095180511,
0.06692656874656677,
-0.03901753947138786,
0.02006794698536396,
-0.026436157524585724,
0.039843473583459854,
-0.07562286406755447,
0.027972087264060974,
-0.009532579220831394,
-0.04921523854136467,
4.996061477951916e-33,
-0.02019149251282215,
0.03643352910876274,
-0.06859130412340164,
0.058177411556243896,
-0.023266945034265518,
-0.0012342754052951932,
-0.018756840378046036,
-0.10439451038837433,
0.04845434054732323,
-0.023334641009569168,
-0.06264585256576538,
0.010637922212481499,
0.08028782159090042,
0.031189003959298134,
-0.015510768629610538,
-0.00807193573564291,
-0.028116246685385704,
-0.040428128093481064,
-0.0015554327983409166,
-0.09655459970235825,
0.006154433824121952,
-0.023927411064505577,
-0.040688320994377136,
-0.044058334082365036,
0.012103458866477013,
0.011595075018703938,
-0.048966873437166214,
0.04026608541607857,
0.04114420339465141,
-0.009154831059277058,
-0.057373277842998505,
-0.006608632858842611,
-0.059441763907670975,
0.015381543897092342,
0.008063510991632938,
0.07021219283342361,
-0.030669214203953743,
-0.04100246727466583,
-0.01660669408738613,
0.06619609147310257,
0.04405348002910614,
0.0174116101115942,
0.013660380616784096,
-0.0028560617938637733,
0.03991391509771347,
-0.027538251131772995,
-0.09471013396978378,
0.10244190692901611,
-0.022098558023571968,
-0.045418862253427505,
-0.0011949180625379086,
-0.1064685732126236,
0.06525298207998276,
0.008771749213337898,
-0.020145684480667114,
0.0037183784879744053,
-0.021392837166786194,
0.012528199702501297,
0.07325821369886398,
0.06969711184501648,
0.005654092878103256,
-0.029830574989318848,
-0.021254805848002434,
0.1212831512093544,
0.015828004106879234,
0.039445191621780396,
-0.09739653021097183,
-0.015718957409262657,
0.030017312616109848,
0.007729784585535526,
-0.015268913470208645,
-0.016290299594402313,
0.12630875408649445,
0.01256848406046629,
0.02723643369972706,
-0.034144606441259384,
-0.0479765459895134,
0.11713947355747223,
0.021125078201293945,
0.05404648557305336,
0.037643518298864365,
-0.10828740149736404,
0.042023491114377975,
0.07273580133914948,
-0.10498742759227753,
0.0053478567861020565,
0.042922936379909515,
-0.07440248876810074,
0.004009794443845749,
0.002613130258396268,
0.08581971377134323,
-0.024630118161439896,
0.02452273666858673,
-0.03327608108520508,
-0.03760626167058945,
-4.491812972357541e-33,
0.0024634795263409615,
-0.010470034554600716,
0.04010926932096481,
-0.02189001627266407,
0.041356027126312256,
0.006120579782873392,
-0.011461537331342697,
-0.042194295674562454,
0.061338040977716446,
-0.02542887255549431,
0.1224619522690773,
0.04060376062989235,
-0.02622542902827263,
-0.14092940092086792,
-0.0038078762590885162,
-0.02817549929022789,
-0.002347443951293826,
0.004497536923736334,
-0.002129499800503254,
0.005682781338691711,
-0.04410030320286751,
0.012660068459808826,
-0.018400175496935844,
0.0628676787018776,
-0.021867923438549042,
-0.022365128621459007,
-0.01875249855220318,
-0.009772032499313354,
0.05944232642650604,
0.05411408096551895,
-0.0373658649623394,
0.03804901987314224,
-0.08316706866025925,
-0.019861239939928055,
0.01450484711676836,
0.02889709174633026,
0.08332575112581253,
-0.03994135186076164,
-0.09078355133533478,
-0.038394808769226074,
-0.0006211864529177547,
0.03893684223294258,
-0.004272559192031622,
0.05618477612733841,
0.020792299881577492,
0.10100553184747696,
-0.04423723742365837,
-0.014886198565363884,
-0.03631631284952164,
0.027192169800400734,
-0.005732371937483549,
-0.07557209581136703,
-0.0212142001837492,
0.002797168679535389,
0.03965671733021736,
-0.0026900828815996647,
0.06307394802570343,
-0.061403948813676834,
0.0508720725774765,
0.029108526185154915,
-0.000481467810459435,
0.02605709247291088,
-0.011665639467537403,
-0.013586005195975304,
-0.007718035951256752,
0.00015119407908059657,
-0.026463376358151436,
0.09336947649717331,
0.11235256493091583,
-0.030370451509952545,
0.044700223952531815,
0.0362972617149353,
0.034044135361909866,
-0.0034956990275532007,
-0.09425699710845947,
0.027088677510619164,
-0.04458000138401985,
0.007308135274797678,
0.054970283061265945,
-0.007160816807299852,
0.028475390747189522,
-0.0027751114685088396,
-0.09613528102636337,
0.0490877740085125,
0.03483390063047409,
0.008504259400069714,
-0.03815427049994469,
0.03219525143504143,
-0.0968356803059578,
-0.09105234593153,
0.00927024520933628,
-0.05935746058821678,
-0.030603760853409767,
0.07161272317171097,
-0.046097468584775925,
-3.9461912848537395e-8,
0.10541699826717377,
-0.09480918943881989,
-0.07100652158260345,
-0.05884239077568054,
-0.07180511206388474,
-0.031248891726136208,
-0.01481776125729084,
0.07005041837692261,
0.029495345428586006,
0.04245518147945404,
0.03780939429998398,
0.05857662856578827,
0.04378795251250267,
-0.029955381527543068,
-0.030558843165636063,
0.06261920183897018,
0.058010999113321304,
0.01876245252788067,
-0.02161503955721855,
-0.031441617757081985,
-0.04464041441679001,
0.06321742385625839,
-0.03299985080957413,
-0.023474983870983124,
0.03876213729381561,
-0.012184514664113522,
-0.04928809031844139,
-0.01261155866086483,
-0.010506385006010532,
-0.07327141612768173,
0.04359595477581024,
-0.0031629791483283043,
0.04447725787758827,
0.023725640028715134,
-0.0012802969431504607,
0.08537426590919495,
0.02750072255730629,
-0.043965794146060944,
-0.014368219301104546,
0.09656918048858643,
-0.028542034327983856,
-0.01141879241913557,
-0.01606421358883381,
0.011648379266262054,
-0.09521757811307907,
-0.079408660531044,
-0.058110371232032776,
-0.0003694860206451267,
-0.042606107890605927,
-0.05212762951850891,
0.01851465180516243,
0.018955975770950317,
0.029875533655285835,
-0.03267855942249298,
-0.06611698120832443,
-0.026617523282766342,
0.045389022678136826,
-0.0076811593025922775,
0.037914760410785675,
-0.004884089808911085,
0.011937597766518593,
0.0018484542379155755,
0.03615724295377731,
-0.004853401333093643
] |
PMID:9457244 | Modifications around the dipeptide-mimetic core of a hydroxamic acid based matrix metalloproteinase inhibitor were studied. | [
-0.013745066709816456,
-0.14476972818374634,
-0.05807074159383774,
0.009444373659789562,
0.0395771861076355,
0.01898076944053173,
-0.0720677301287651,
0.10045849531888962,
0.04843852296471596,
-0.03818513825535774,
0.01054431963711977,
0.015779871493577957,
0.04485880583524704,
0.051092859357595444,
-0.04897268861532211,
0.07262548804283142,
0.0026479847729206085,
0.023929910734295845,
0.05730828642845154,
0.004079492297023535,
-0.018341556191444397,
-0.04435509070754051,
-0.05247015506029129,
-0.0016763934399932623,
-0.08608419448137283,
0.0801544040441513,
-0.0058264778926968575,
0.027512921020388603,
-0.07723034173250198,
0.0077637722715735435,
0.00723769748583436,
-0.00040677233482711017,
0.08965183049440384,
-0.059618473052978516,
0.041998378932476044,
-0.014681525528430939,
-0.07819437980651855,
0.014335324987769127,
-0.024762975051999092,
0.027798287570476532,
0.13077616691589355,
0.0066722603514790535,
0.028830688446760178,
-0.07950031012296677,
0.05980544537305832,
-0.030967267230153084,
0.06299028545618057,
-0.05145720764994621,
0.023724544793367386,
0.1915624439716339,
-0.09037382155656815,
-0.053586285561323166,
0.008803085424005985,
0.023040950298309326,
-0.06658067554235458,
-0.12593430280685425,
-0.05382966622710228,
0.07898493856191635,
0.05660642310976982,
-0.01638934202492237,
0.01295294240117073,
-0.0004908593255095184,
0.0907810628414154,
-0.005880274344235659,
0.004399825818836689,
-0.06327994912862778,
0.040835075080394745,
-0.056923869997262955,
-0.012358477339148521,
-0.07468284666538239,
-0.03951707482337952,
-0.05354239046573639,
0.02756555750966072,
-0.03287471830844879,
-0.024112151935696602,
-0.005527043249458075,
0.01387050561606884,
-0.003883992787450552,
0.04397469013929367,
0.019298074766993523,
0.09131330251693726,
0.05249578505754471,
-0.006886664777994156,
0.02618836611509323,
-0.004487570840865374,
0.0896691158413887,
0.046676792204380035,
-0.030645322054624557,
-0.007677980232983828,
-0.05226318538188934,
0.05083455517888069,
-0.03408198803663254,
-0.04896945133805275,
-0.04507621005177498,
-0.0037055290304124355,
0.032919399440288544,
-0.08974862098693848,
0.023311473429203033,
-0.08909694105386734,
-0.02016097865998745,
0.012674772180616856,
0.01580173149704933,
-0.1085917130112648,
-0.02969341352581978,
-0.0013459823094308376,
-0.014866539277136326,
0.04208729416131973,
0.06235277280211449,
-0.01685655489563942,
-0.03623953089118004,
0.004390559624880552,
0.036336418241262436,
-0.017678627744317055,
0.023612720891833305,
0.026213403791189194,
0.0033528590574860573,
0.09904568642377853,
-0.028634820133447647,
-0.019875170662999153,
0.008869990706443787,
0.0591217465698719,
-0.015144421719014645,
0.03522679582238197,
0.057415466755628586,
0.0009584857616573572,
0.06006670743227005,
-0.052160777151584625,
1.606871757557281e-33,
0.057951293885707855,
0.018109003081917763,
0.10323941707611084,
-0.009240825660526752,
-0.07257412374019623,
-0.099788136780262,
-0.00839999783784151,
-0.02336963452398777,
0.04784783720970154,
0.042890340089797974,
-0.05042743682861328,
-0.00935022160410881,
0.09700579196214676,
0.002102992497384548,
-0.008429285138845444,
-0.037517279386520386,
0.060267556458711624,
-0.08090493828058243,
0.048573993146419525,
-0.08203301578760147,
-0.002794684376567602,
0.059752095490694046,
-0.028544288128614426,
0.006427037063986063,
-0.032545819878578186,
0.05521811917424202,
-0.056276850402355194,
-0.07365106791257858,
0.09576281905174255,
-0.0369173027575016,
-0.0663791224360466,
-0.030303359031677246,
-0.06862292438745499,
0.06625766307115555,
0.06206381320953369,
-0.08438523858785629,
0.029990654438734055,
-0.07675434648990631,
0.05192805081605911,
-0.03202323615550995,
-0.0904088094830513,
0.000755462737288326,
0.00236139795742929,
-0.07850445061922073,
0.0805896446108818,
-0.05557681620121002,
-0.0704956203699112,
0.003550840774551034,
-0.011482058092951775,
-0.006410478614270687,
0.075330950319767,
-0.008582398295402527,
0.08761271089315414,
0.010272129438817501,
-0.058473244309425354,
0.0537472628057003,
-0.07364542037248611,
0.04776698723435402,
0.03464438021183014,
0.05400572717189789,
-0.07120920717716217,
-0.043238863348960876,
-0.062496479600667953,
-0.004250265192240477,
-0.04676790535449982,
0.039938610047101974,
-0.026154888793826103,
0.010845469310879707,
0.028030920773744583,
0.0690966248512268,
-0.03310852125287056,
0.06745851039886475,
0.05602189525961876,
0.0640883520245552,
-0.026387928053736687,
-0.031774889677762985,
-0.01296178251504898,
-0.0008306184899993241,
0.054467737674713135,
0.056172627955675125,
0.10577253997325897,
0.08511386811733246,
-0.02082005888223648,
0.016643885523080826,
-0.06842552125453949,
0.0030314428731799126,
0.05701392889022827,
-0.027184581384062767,
-0.0019729805644601583,
0.0075074792839586735,
0.029147673398256302,
-0.006150479428470135,
0.01372466143220663,
0.04135071486234665,
-0.009702889248728752,
-3.364365483757176e-33,
0.06605876982212067,
-0.16477049887180328,
0.052461303770542145,
-0.09366925805807114,
-0.005888584069907665,
-0.051001038402318954,
0.04603056609630585,
-0.031228082254529,
0.062160246074199677,
-0.026690524071455002,
0.10968604683876038,
-0.03455168753862381,
-0.012599986977875233,
-0.012212632223963737,
-0.033946700394153595,
0.03175963833928108,
-0.08782508969306946,
0.018506871536374092,
0.009360956959426403,
-0.06926441192626953,
-0.00839988049119711,
0.001274747308343649,
0.12342476099729538,
0.002064606174826622,
0.03239896148443222,
-0.017064029350876808,
-0.04189183935523033,
0.01458643190562725,
0.11677096039056778,
0.09446871280670166,
-0.05391072854399681,
0.05487360432744026,
-0.025054829195141792,
-0.04114314541220665,
0.011637985706329346,
0.02933427318930626,
-0.0739031508564949,
-0.007875614799559116,
0.00047084823017939925,
0.002253215294331312,
-0.03443840518593788,
-0.03340119495987892,
0.030672656372189522,
0.034150153398513794,
0.07454434037208557,
0.10842082649469376,
-0.030250495299696922,
0.011535021476447582,
-0.01647406443953514,
-0.039775729179382324,
-0.06697004288434982,
-0.012729772366583347,
-0.03186354413628578,
-0.014476810581982136,
0.04901617392897606,
0.030547460541129112,
0.07442311942577362,
-0.046997085213661194,
-0.0017661168240010738,
-0.007532855495810509,
-0.00821948517113924,
-0.027234412729740143,
0.009117592126131058,
-0.029921814799308777,
-0.011661588214337826,
0.13971461355686188,
0.11662213504314423,
0.05466599389910698,
0.019946184009313583,
-0.026536501944065094,
0.060102105140686035,
-0.020103849470615387,
0.034695643931627274,
-0.013017491437494755,
0.027496518567204475,
-0.03689455986022949,
-0.03756101429462433,
-0.018500033766031265,
-0.0018891881918534636,
-0.032407037913799286,
0.014599841088056564,
0.03958924859762192,
-0.06394653767347336,
-0.09238442778587341,
0.025102021172642708,
-0.009641002863645554,
-0.04237202927470207,
0.04803503677248955,
-0.018629303202033043,
-0.027810102328658104,
-0.008829261176288128,
-0.07525140047073364,
0.05764611437916756,
0.056544918566942215,
-0.0016235914081335068,
-2.7626994025808926e-8,
-0.020871425047516823,
-0.01889941841363907,
0.014431319199502468,
-0.0868300050497055,
-0.029281165450811386,
0.05817971006035805,
-0.03880756348371506,
-0.05790415778756142,
0.004123011603951454,
-0.021531032398343086,
0.023008354008197784,
-0.038741208612918854,
-0.06009206175804138,
-0.05535858869552612,
-0.02386339008808136,
-0.002848347881808877,
-0.04327623173594475,
-0.0016463790088891983,
0.045014481991529465,
0.004026505164802074,
-0.01886865869164467,
0.02594766579568386,
-0.0701185017824173,
-0.051151398569345474,
-0.036296602338552475,
-0.010417109355330467,
0.023220140486955643,
0.0037115884479135275,
-0.05480518937110901,
-0.015299041755497456,
-0.037673402577638626,
0.03331534564495087,
0.05629695951938629,
0.04856474697589874,
-0.021326957270503044,
0.018146062269806862,
0.00298673240467906,
0.06452424824237823,
-0.046951282769441605,
0.0128866508603096,
-0.005485194269567728,
-0.04812063276767731,
-0.054433729499578476,
-0.06909070163965225,
-0.0020380381029099226,
0.04433366283774376,
0.031338371336460114,
0.05458739027380943,
0.03421007841825485,
-0.029530690982937813,
0.0012308490695431828,
0.018933994695544243,
-0.054946284741163254,
-0.02107648365199566,
-0.013659896329045296,
0.014524404890835285,
0.00687911082059145,
-0.09030929207801819,
0.03118213266134262,
-0.09512684494256973,
-0.03193478286266327,
-0.07985135912895203,
0.06880038231611252,
0.030841389670968056
] |
PMID:9457244 | These variations incorporated a variety of natural, unnatural, and synthetic amino acids in addition to modifications of the P1' and P3' substituents. | [
-0.015831002965569496,
-0.12660422921180725,
0.00023221212904900312,
-0.05412514507770538,
0.02307399921119213,
0.06900760531425476,
-0.0125690046697855,
0.037400905042886734,
0.027841705828905106,
0.025274062529206276,
0.03154183179140091,
0.04139912128448486,
-0.11157476156949997,
-0.015934335067868233,
0.04523076117038727,
0.009985857643187046,
-0.05392182245850563,
0.08090363442897797,
0.011000423692166805,
-0.016983838751912117,
0.05649520456790924,
0.048101820051670074,
0.029148917645215988,
0.05456717684864998,
0.0035727866925299168,
0.06492840498685837,
0.0828210860490799,
0.05551452562212944,
0.09079480171203613,
-0.05142071470618248,
-0.004180225543677807,
-0.02030978724360466,
0.06676018238067627,
-0.09545275568962097,
0.02397051639854908,
0.0006776638911105692,
-0.1364193558692932,
0.0072837043553590775,
0.018590549007058144,
0.025384556502103806,
0.07982243597507477,
-0.016001634299755096,
0.01977909728884697,
-0.05253506451845169,
-0.04674573242664337,
-0.03067091666162014,
-0.03557572513818741,
-0.026532107964158058,
0.009582441300153732,
0.0008471803739666939,
0.020925775170326233,
-0.05919024348258972,
-0.11626528948545456,
0.00021324283443391323,
0.0351470410823822,
-0.030699728056788445,
-0.07910847663879395,
0.05528701841831207,
-0.007223957218229771,
-0.017166433855891228,
0.01841471716761589,
0.022109031677246094,
0.006237252149730921,
-0.04955659061670303,
0.022368203848600388,
0.022054776549339294,
0.03813091292977333,
-0.08459579199552536,
0.07187195122241974,
0.013612208887934685,
-0.052954357117414474,
0.007353684399276972,
-0.015817692503333092,
0.03117263689637184,
-0.02719850279390812,
0.033657051622867584,
0.031444910913705826,
0.020265519618988037,
-0.05637366697192192,
-0.07295537739992142,
0.00887411180883646,
0.03724440932273865,
-0.03213951364159584,
0.12249385565519333,
0.0517297200858593,
0.02315412275493145,
-0.053587719798088074,
-0.005272719543427229,
-0.006239873357117176,
-0.016647547483444214,
0.07314005494117737,
-0.02299378626048565,
-0.00980606209486723,
-0.02147895283997059,
-0.03182153403759003,
0.029952513054013252,
-0.0028032956179231405,
-0.008059093728661537,
0.11822478473186493,
0.0028292646165937185,
0.04098191857337952,
0.08109516650438309,
-0.03165425360202789,
-0.058334656059741974,
-0.05810150131583214,
0.025174133479595184,
-0.07171351462602615,
-0.044454578310251236,
-0.03350061550736427,
0.05282954126596451,
-0.05887686088681221,
-0.014492299407720566,
-0.006216311827301979,
-0.10462610423564911,
-0.06939605623483658,
0.016141915693879128,
0.048451103270053864,
-0.0033497277181595564,
0.017230115830898285,
0.010218502953648567,
0.03245438262820244,
-0.031145794317126274,
0.08801598101854324,
0.06634114682674408,
-0.08809150755405426,
-0.022348595783114433,
-0.08227740228176117,
-2.5379013033039422e-33,
0.04121691361069679,
0.010125601664185524,
0.0377415232360363,
0.06704094260931015,
0.07486787438392639,
-0.00604157755151391,
-0.042993731796741486,
-0.09198629856109619,
-0.006310021970421076,
-0.021652767434716225,
-0.06816109269857407,
-0.020533740520477295,
0.027566205710172653,
0.03082183562219143,
-0.00513731874525547,
-0.044193536043167114,
-0.0686720758676529,
0.01280798576772213,
0.06396371871232986,
-0.008204178884625435,
-0.013998480513691902,
0.08244993537664413,
0.029520444571971893,
0.015921834856271744,
-0.006107528228312731,
-0.014972764998674393,
0.024005336686968803,
0.03811216354370117,
0.000009846145076153334,
-0.05323216691613197,
-0.0050605046562850475,
-0.017584925517439842,
-0.10284450650215149,
-0.03953535482287407,
-0.017276303842663765,
-0.0047087050043046474,
-0.029598496854305267,
-0.08792170882225037,
0.030122101306915283,
0.10258034616708755,
0.060621507465839386,
-0.005354271270334721,
0.011440804228186607,
-0.02838384173810482,
0.07622850686311722,
0.048525370657444,
-0.028777986764907837,
0.12293510138988495,
-0.05500340089201927,
0.003554864786565304,
0.050277989357709885,
0.021707072854042053,
0.030547190457582474,
0.03163021802902222,
-0.04290160536766052,
-0.04443224146962166,
-0.06330808252096176,
-0.012995210476219654,
0.03623822703957558,
0.019233426079154015,
0.03900989890098572,
0.023787032812833786,
0.05782086029648781,
0.017287425696849823,
-0.02604379691183567,
0.04260644316673279,
-0.06111692637205124,
-0.010042722336947918,
0.008140289224684238,
0.059660471975803375,
-0.0824926421046257,
-0.04711645469069481,
-0.012417069636285305,
0.04684828966856003,
0.032928138971328735,
-0.06253314763307571,
-0.090279720723629,
0.06680721789598465,
0.02873985841870308,
0.02396978810429573,
-0.0307609923183918,
0.02396453358232975,
-0.0437784306704998,
0.0953570008277893,
-0.1169610321521759,
-0.05566590651869774,
0.03710508346557617,
-0.06284907460212708,
0.06707435101270676,
-0.0010039247572422028,
0.04487098380923271,
-0.09955255687236786,
-0.005354450549930334,
0.006293997634202242,
-0.007359471637755632,
7.46123549678346e-34,
-0.008101717568933964,
-0.06958670914173126,
-0.02525385655462742,
0.00719083845615387,
-0.04922919720411301,
-0.010633960366249084,
0.034551192075014114,
-0.04403577372431755,
0.003917986992746592,
-0.0034049961250275373,
0.07902926951646805,
-0.0028847763314843178,
-0.014190291054546833,
-0.13861136138439178,
-0.053190626204013824,
0.017094599083065987,
-0.0489681102335453,
0.11739549040794373,
0.004546399228274822,
-0.011353577487170696,
0.06681206822395325,
0.047094471752643585,
-0.01460607722401619,
-0.02520463988184929,
0.016752716153860092,
0.058981992304325104,
-0.03984186425805092,
0.09128917753696442,
0.07170847058296204,
0.051059771329164505,
-0.04834799841046333,
0.036656953394412994,
-0.06945370137691498,
-0.028814254328608513,
-0.01580600067973137,
0.03243362531065941,
-0.022038733586668968,
0.028065109625458717,
0.025105345994234085,
-0.010853412561118603,
-0.022150635719299316,
0.1183529645204544,
0.14048820734024048,
0.051393020898103714,
0.07506908476352692,
0.04722657427191734,
0.020548177883028984,
-0.0740598663687706,
-0.056604016572237015,
-0.06018313020467758,
0.03514418378472328,
-0.04469501972198486,
-0.02806313894689083,
-0.01217060536146164,
0.049438826739788055,
-0.024569053202867508,
0.0036231132689863443,
0.012487700209021568,
0.05101281404495239,
0.012631765566766262,
-0.09513674676418304,
-0.06277189403772354,
0.05774085596203804,
-0.04806892201304436,
-0.061143722385168076,
0.010148774832487106,
-0.030339080840349197,
-0.039680298417806625,
0.03685126453638077,
-0.03299529105424881,
0.030207911506295204,
-0.03465957194566727,
0.10630082339048386,
0.027309885248541832,
0.07020638883113861,
-0.02262912504374981,
0.002927421359345317,
0.032869018614292145,
-0.011820108629763126,
-0.023597341030836105,
-0.04816143959760666,
-0.04672502353787422,
-0.05329541489481926,
-0.0026473908219486475,
-0.010619421489536762,
0.030708767473697662,
-0.018631543964147568,
0.09318318217992783,
-0.005533954594284296,
-0.003425589529797435,
-0.042759351432323456,
0.028565118089318275,
-0.0062836636789143085,
0.13928477466106415,
0.08433248847723007,
-2.916770114325118e-8,
0.055843535810709,
-0.036298081278800964,
-0.008817444555461407,
0.043292999267578125,
0.006225359160453081,
0.03392462804913521,
-0.0651213750243187,
0.024778513237833977,
-0.04201764240860939,
-0.08417151123285294,
-0.03430987894535065,
0.07692299038171768,
0.05449427291750908,
0.045221779495477676,
-0.0008007715805433691,
0.10587693750858307,
-0.1321115791797638,
-0.006224087905138731,
-0.034812476485967636,
-0.021118897944688797,
-0.07435370236635208,
0.09678938239812851,
-0.07145026326179504,
-0.03294478729367256,
0.027867255732417107,
-0.013901062309741974,
-0.041483234614133835,
-0.02457052282989025,
-0.017141450196504593,
-0.008334620855748653,
0.0648861676454544,
0.02683337964117527,
0.039933521300554276,
-0.04093140363693237,
0.0011388490675017238,
0.0699315220117569,
-0.019046520814299583,
-0.026250893250107765,
-0.032957594841718674,
-0.03581911325454712,
-0.012075633741915226,
-0.11902878433465958,
-0.07876411080360413,
0.00988144800066948,
0.03498073294758797,
-0.05486267805099487,
-0.07459460943937302,
0.07178885489702225,
-0.1026754304766655,
0.029675381258130074,
0.05460438132286072,
0.044135160744190216,
0.00819331593811512,
-0.06321432441473007,
-0.04148702323436737,
0.0010946543188765645,
-0.008354473859071732,
-0.047565657645463943,
0.013508657924830914,
-0.04065076634287834,
-0.057194825261831284,
-0.019704710692167282,
0.09346066415309906,
0.016189584508538246
] |
PMID:9457244 | The results of this study indicate the following structural requirements: (1) Two key hydrogen bonds must be present between the enzyme and potent substrates. | [
-0.04231410473585129,
-0.09518340229988098,
-0.0904797837138176,
-0.05706555023789406,
-0.000030247492759372108,
0.012778552249073982,
-0.08839596062898636,
0.04912760853767395,
-0.01231271680444479,
-0.07927558571100235,
0.02545567788183689,
-0.03208719938993454,
-0.059683725237846375,
0.06663911044597626,
-0.006563722155988216,
-0.050931669771671295,
-0.0460926853120327,
-0.040101855993270874,
0.03257910907268524,
0.024349626153707504,
0.08325155079364777,
-0.09521765261888504,
0.04653472825884819,
-0.042714402079582214,
-0.008030624128878117,
0.0690380409359932,
0.10418861359357834,
-0.017724428325891495,
-0.021277643740177155,
-0.0788574293255806,
0.05255206674337387,
-0.07574082911014557,
0.07162324339151382,
-0.045282553881406784,
0.0067129372619092464,
0.07879561185836792,
-0.03352447226643562,
-0.10105787962675095,
-0.005684817675501108,
-0.006471488159149885,
0.04420316219329834,
-0.015208357013761997,
0.036412373185157776,
-0.03324653208255768,
0.014794033952057362,
-0.062213294208049774,
0.02611321024596691,
-0.032343052327632904,
-0.03135070949792862,
-0.0017191433580592275,
-0.030524203553795815,
-0.04920649155974388,
0.020952189341187477,
-0.025681525468826294,
-0.05850933864712715,
0.07050719857215881,
-0.05051563307642937,
0.0878729596734047,
-0.06078639253973961,
0.007015565410256386,
0.05367531254887581,
0.0418800488114357,
0.001389558776281774,
-0.044419366866350174,
0.023662814870476723,
-0.049086518585681915,
0.059566207230091095,
-0.054241281002759933,
-0.002884300658479333,
0.011947656981647015,
-0.08612831681966782,
-0.0820549726486206,
-0.06488804519176483,
-0.0420701801776886,
0.026779741048812866,
0.0008182491292245686,
-0.026777738705277443,
-0.021542610600590706,
0.0386836938560009,
-0.04072526469826698,
0.008225602097809315,
0.013920783065259457,
0.006024103611707687,
0.11368502676486969,
0.04328446462750435,
0.02216082438826561,
0.03290595859289169,
-0.02792837657034397,
-0.006628996692597866,
-0.02505042962729931,
0.04918958246707916,
-0.003818830009549856,
-0.07841630280017853,
-0.006780858617275953,
-0.008046379312872887,
0.07872180640697479,
0.02571692131459713,
0.027554122731089592,
0.03141811862587929,
-0.036112237721681595,
0.034767527133226395,
0.0639304518699646,
-0.0295966025441885,
-0.016736915335059166,
-0.02955389954149723,
0.026917845010757446,
-0.01208429504185915,
0.08719997107982635,
0.07245049625635147,
0.015975961461663246,
0.016412774100899696,
-0.00003376500171725638,
0.027972964569926262,
-0.0304922666400671,
-0.0213327519595623,
0.0337664969265461,
-0.05071346089243889,
-0.028344959020614624,
-0.02919449657201767,
-0.005581236910074949,
0.007550404407083988,
-0.015063895843923092,
0.03845231980085373,
0.01191909983754158,
-0.036426253616809845,
-0.041919950395822525,
-0.11100839823484421,
-2.1885572392090205e-33,
0.053482476621866226,
0.012150847353041172,
-0.015270472504198551,
-0.05044546350836754,
-0.0371251255273819,
-0.023071208968758583,
-0.10664629936218262,
0.0279752928763628,
-0.06710683554410934,
-0.07355963438749313,
-0.06609221547842026,
-0.11148723214864731,
0.04852050542831421,
-0.01737861894071102,
-0.03802059590816498,
-0.0066831642761826515,
0.059959106147289276,
0.06065165624022484,
0.057946350425481796,
0.07664738595485687,
-0.04316483065485954,
0.004409154411405325,
-0.036636240780353546,
0.014891277067363262,
0.02624756470322609,
-0.007869253866374493,
0.019576840102672577,
-0.031616952270269394,
-0.0048199123702943325,
-0.01458000298589468,
-0.0014543547295033932,
-0.07852184772491455,
-0.04815392568707466,
0.026673270389437675,
0.059419699013233185,
0.034807439893484116,
-0.04283427819609642,
0.029953762888908386,
-0.014341582544147968,
-0.06605896353721619,
0.042224109172821045,
0.05867224559187889,
0.05188906937837601,
-0.006964831613004208,
0.07303600758314133,
0.015904873609542847,
0.03029668517410755,
0.06905427575111389,
0.006950343493372202,
0.04179833456873894,
0.01625981554389,
-0.02446041628718376,
0.10215162485837936,
0.006487607955932617,
-0.025682659819722176,
0.08300302177667618,
-0.0456375889480114,
0.034825097769498825,
0.03138135001063347,
0.049221061170101166,
-0.07749535888433456,
0.08628048002719879,
-0.09293927252292633,
0.05650964006781578,
-0.0030437451787292957,
0.09395944327116013,
-0.09482081234455109,
-0.044850125908851624,
0.025194549933075905,
0.13834303617477417,
-0.037345077842473984,
-0.01664675585925579,
-0.019358497112989426,
0.04052500054240227,
-0.01780948042869568,
-0.012606481090188026,
-0.017126096412539482,
-0.022088076919317245,
0.09352406859397888,
0.07619122415781021,
-0.009196378290653229,
-0.017329907044768333,
0.05590597912669182,
-0.042936060577631,
-0.11724893748760223,
-0.060767851769924164,
0.01564858667552471,
-0.03399268165230751,
-0.004167621955275536,
0.1265956163406372,
0.055931903421878815,
-0.08149151504039764,
0.04287654533982277,
-0.019544512033462524,
0.0111036766320467,
-3.5031706117671565e-34,
0.08684944361448288,
-0.05091778561472893,
0.018358102068305016,
-0.08528132736682892,
0.015529930591583252,
0.07343850284814835,
0.010692931711673737,
-0.11628330498933792,
0.04441780969500542,
-0.017657477408647537,
0.10156366229057312,
-0.040502164512872696,
-0.029838059097528458,
-0.060659412294626236,
-0.0358753427863121,
0.0911993533372879,
-0.0767526626586914,
0.06411038339138031,
0.07878818362951279,
0.04065234959125519,
0.02222435176372528,
0.08003749698400497,
0.01606224849820137,
0.08149648457765579,
0.06432969868183136,
-0.03667408972978592,
-0.019175292924046516,
-0.0010354053229093552,
0.0326206237077713,
0.013893668539822102,
-0.02557547390460968,
-0.04489654675126076,
-0.019749058410525322,
0.007027416490018368,
0.009604280814528465,
0.05191611498594284,
-0.026012349873781204,
-0.01806657575070858,
0.010783208534121513,
0.020777467638254166,
0.027225060388445854,
0.015083069913089275,
-0.02340363711118698,
0.0026857296470552683,
0.02225789800286293,
0.07276925444602966,
-0.04933641105890274,
0.03599794954061508,
-0.040496356785297394,
-0.04412699118256569,
0.0034256724175065756,
-0.024731401354074478,
-0.02296910248696804,
-0.05140409991145134,
0.0065936255268752575,
0.023755483329296112,
0.0033291124273091555,
0.02959499880671501,
0.013187907636165619,
-0.03046361356973648,
-0.01761188544332981,
-0.00021584457135759294,
0.029339587315917015,
0.016568953171372414,
-0.04104732722043991,
-0.04515384882688522,
0.014741859398782253,
0.04171086475253105,
-0.005858903285115957,
-0.05152508243918419,
0.02226720191538334,
0.004591798409819603,
0.10996397584676743,
0.11315326392650604,
-0.004634997807443142,
-0.06715850532054901,
-0.06642916053533554,
-0.06402572989463806,
0.020673591643571854,
-0.008543003350496292,
0.02688990719616413,
0.09101495891809464,
-0.055000919848680496,
-0.03787853941321373,
0.04645957797765732,
-0.01915203593671322,
0.04506254196166992,
0.055237602442502975,
-0.005497890058904886,
0.0065046874806284904,
0.046757154166698456,
0.017781740054488182,
-0.06920962780714035,
0.08236061036586761,
0.08748310804367065,
-3.2373595360013496e-8,
0.06021253019571304,
-0.10549241304397583,
0.035290203988552094,
-0.068720743060112,
-0.0038593404460698366,
0.11387661844491959,
0.02529757283627987,
-0.06122998893260956,
0.022232741117477417,
-0.0050501697696745396,
-0.007122189272195101,
0.0634315013885498,
-0.06699132919311523,
0.055148981511592865,
-0.04263938218355179,
-0.04095108434557915,
-0.04444262012839317,
0.0006816613604314625,
-0.052779633551836014,
0.003472565906122327,
-0.04050413891673088,
0.01701762154698372,
-0.14534293115139008,
0.001325864577665925,
0.04109785705804825,
-0.09393671154975891,
-0.00455652317032218,
0.04875611513853073,
-0.05184169486165047,
-0.021879859268665314,
0.04015754535794258,
0.04693141207098961,
-0.009569571353495121,
0.013211647048592567,
-0.004192884545773268,
-0.004701326601207256,
-0.005736415274441242,
0.05381501838564873,
-0.06786598265171051,
0.061263926327228546,
0.039640191942453384,
-0.04175548255443573,
-0.04096980765461922,
-0.006281966343522072,
0.030590103939175606,
0.04853761941194534,
-0.03230312839150429,
0.08078774064779282,
-0.025957033038139343,
0.032524485141038895,
0.012534210458397865,
-0.014802778139710426,
-0.018610693514347076,
-0.08993837237358093,
-0.04700981453061104,
0.038334861397743225,
-0.01213553361594677,
-0.027385810390114784,
-0.004974070470780134,
-0.15282034873962402,
0.11950569599866867,
0.037933606654405594,
0.12273310124874115,
-0.06433164328336716
] |
PMID:9457244 | (2) Potent inhibitors must possess strong zinc-binding functionalities. | [
-0.027519024908542633,
-0.027093879878520966,
-0.03253588825464249,
0.029801098629832268,
0.02239708974957466,
-0.005626261234283447,
-0.034234434366226196,
0.033919356763362885,
0.033018626272678375,
0.014264789409935474,
-0.03964713588356972,
0.03791624307632446,
0.0630582869052887,
0.03943657502532005,
0.006930068600922823,
0.05069372430443764,
0.029344651848077774,
0.06011942774057388,
-0.013800596818327904,
0.06864821165800095,
-0.013221671804785728,
0.05441264435648918,
0.0409754179418087,
-0.022424103692173958,
-0.05606723949313164,
0.06563787907361984,
-0.04696386680006981,
0.07833630591630936,
0.027804553508758545,
0.009116500616073608,
-0.027401983737945557,
0.02683371677994728,
0.018078656867146492,
0.019995909184217453,
-0.07796669006347656,
-0.019630517810583115,
-0.018814291805028915,
0.019224660471081734,
-0.0364290215075016,
-0.008707436732947826,
0.09102082252502441,
0.04706374555826187,
-0.007992725819349289,
-0.041709061712026596,
0.026380721479654312,
-0.09759505838155746,
-0.003307008882984519,
-0.03481413051486015,
-0.03611236438155174,
0.076097771525383,
-0.06265139579772949,
-0.02478484809398651,
-0.004191018175333738,
0.06121181696653366,
-0.004058100748807192,
0.059289008378982544,
-0.12587201595306396,
0.12455127388238907,
0.028583820909261703,
0.0016245513688772917,
0.013815391808748245,
-0.034042052924633026,
0.009054375812411308,
0.014570827595889568,
0.09822716563940048,
-0.0031872594263404608,
-0.03669816255569458,
0.013930754736065865,
-0.03884807229042053,
0.0045330761931836605,
-0.031120074912905693,
-0.020786423236131668,
-0.0007270406349562109,
-0.00037729015457443893,
-0.03540157899260521,
0.05767383053898811,
0.022563805803656578,
-0.07012875378131866,
-0.02816915512084961,
-0.05177511274814606,
0.0427352599799633,
0.03673563897609711,
0.05686135217547417,
0.12993958592414856,
0.04151972755789757,
0.08704724162817001,
-0.03676356375217438,
0.009680281393229961,
-0.012337701395154,
0.032950568944215775,
0.10499107837677002,
0.01886509731411934,
-0.00019628273730631918,
0.008308155462145805,
-0.05992725491523743,
0.014583496376872063,
-0.04448685795068741,
0.023042120039463043,
-0.07574018836021423,
0.0121688861399889,
0.08167567849159241,
0.05399612709879875,
-0.019565299153327942,
-0.079066701233387,
0.036359552294015884,
0.011515573598444462,
0.06515216082334518,
-0.021823246031999588,
-0.0659666657447815,
0.030167169868946075,
0.032927628606557846,
-0.06830129772424698,
0.018653130158782005,
0.01824965886771679,
-0.020850738510489464,
0.025100035592913628,
0.04209013283252716,
0.031529903411865234,
-0.04715728014707565,
-0.05804372578859329,
0.0036545905750244856,
-0.0007614819915033877,
-0.0308113731443882,
-0.05989934504032135,
-0.02513100393116474,
0.030506985262036324,
-0.07705465704202652,
-2.0609407970379527e-33,
-0.03690756484866142,
0.020239172503352165,
0.006623833905905485,
0.07322612404823303,
0.07917685806751251,
-0.01107343565672636,
-0.02019926719367504,
-0.015416176058351994,
-0.04917189106345177,
0.023321932181715965,
-0.07353058457374573,
-0.037746310234069824,
0.04948693513870239,
0.030787751078605652,
-0.00106795784085989,
-0.03524782881140709,
0.08518102765083313,
-0.04047097638249397,
0.0747300311923027,
-0.011895185336470604,
0.10422348976135254,
0.0012217789189890027,
-0.05061354115605354,
-0.0064580366015434265,
-0.015060711652040482,
0.020332781597971916,
-0.024794772267341614,
0.03210717812180519,
-0.00616249768063426,
-0.04722531512379646,
0.024903222918510437,
0.005986216012388468,
-0.04088091850280762,
-0.01601574569940567,
0.1293477863073349,
-0.0804963931441307,
-0.00862677302211523,
-0.0245994720607996,
0.010707496665418148,
-0.1035112589597702,
-0.05827999860048294,
-0.000270870397798717,
-0.11234796792268753,
0.06906010210514069,
0.048646245151758194,
-0.06283725053071976,
-0.06077592074871063,
0.06612826138734818,
-0.011795338243246078,
-0.00782661885023117,
0.057729270309209824,
-0.017328787595033646,
0.002781163901090622,
0.05653893202543259,
-0.13448616862297058,
0.04087692126631737,
-0.05813091993331909,
0.004268364515155554,
0.05492263659834862,
0.04662802815437317,
-0.055915672332048416,
0.040800340473651886,
-0.0945437029004097,
0.07094547152519226,
-0.0027045963797718287,
0.026315180584788322,
-0.08399943262338638,
-0.06378678977489471,
-0.06948403269052505,
0.05375218763947487,
0.02454567328095436,
-0.05160537362098694,
0.04161682352423668,
0.03235718980431557,
0.054656732827425,
-0.03078600950539112,
-0.04014850780367851,
-0.04678499326109886,
0.11388105154037476,
0.05655140429735184,
-0.03279809281229973,
-0.10056580603122711,
-0.04945370927453041,
0.10835439711809158,
-0.10272719711065292,
-0.11143819242715836,
0.033876683562994,
-0.06804430484771729,
0.014401229098439217,
-0.029574114829301834,
0.08659590035676956,
-0.039617184549570084,
-0.04090941697359085,
-0.05477434769272804,
0.005535178817808628,
-2.5470854957682144e-34,
0.04806307703256607,
0.058328691869974136,
0.04809834808111191,
-0.017334751784801483,
0.0001890335261123255,
-0.019151268526911736,
-0.022553298622369766,
-0.17975421249866486,
0.06852889060974121,
-0.08038260787725449,
0.1367332488298416,
0.007913966663181782,
0.026784317567944527,
-0.008440072648227215,
-0.005410047713667154,
0.023975245654582977,
-0.06153537333011627,
-0.008702307008206844,
0.021769188344478607,
-0.05229782313108444,
0.02194049395620823,
-0.028483621776103973,
0.02445276826620102,
0.08235397189855576,
0.005589783191680908,
-0.018982822075486183,
0.05566089227795601,
-0.01080156210809946,
0.024272829294204712,
0.1411837339401245,
-0.012198670767247677,
0.08281763643026352,
-0.06623483449220657,
-0.11116158962249756,
-0.029485411942005157,
0.008593604899942875,
-0.010037433356046677,
-0.03976859524846077,
-0.08139045536518097,
-0.08739539235830307,
-0.015390102751553059,
-0.024538468569517136,
0.01591758243739605,
0.057506248354911804,
0.07313762605190277,
0.05614302679896355,
-0.012020002119243145,
0.04101378098130226,
-0.057608094066381454,
-0.02786906249821186,
0.034167032688856125,
0.07332703471183777,
-0.022077234461903572,
0.00008284534851554781,
0.09729313850402832,
-0.005359969567507505,
0.02181299217045307,
-0.08454751968383789,
0.08153446763753891,
-0.03916092589497566,
-0.03843533620238304,
0.026461884379386902,
-0.029996251687407494,
0.010374912060797215,
-0.022984640672802925,
-0.03368304669857025,
0.08000411838293076,
0.09717576950788498,
0.0904047042131424,
-0.07112258672714233,
0.05058319494128227,
0.04742429405450821,
0.10102479159832001,
0.01308863703161478,
-0.05505049228668213,
0.0391094796359539,
0.03553246706724167,
-0.07160038501024246,
-0.03816096484661102,
0.006349427625536919,
0.025435587391257286,
0.055183932185173035,
-0.00417458638548851,
-0.01695527508854866,
-0.047719042748212814,
0.04523817077279091,
-0.00944603979587555,
0.04401729628443718,
-0.05140836909413338,
0.0223523136228323,
-0.026575133204460144,
-0.06824248284101486,
-0.028763512149453163,
0.05616750195622444,
-0.053991518914699554,
-2.1064696653638748e-8,
-0.04107397049665451,
-0.028770137578248978,
0.03503450006246567,
-0.12911944091320038,
-0.07315584272146225,
0.016882775351405144,
-0.026484675705432892,
0.03470119461417198,
-0.0074834092520177364,
0.027883436530828476,
0.05306949466466904,
0.027199165895581245,
0.0007729337667115033,
0.0008671436808072031,
0.020565783604979515,
0.04360032454133034,
0.007255566772073507,
0.024587135761976242,
-0.05603136122226715,
0.024833209812641144,
-0.036524590104818344,
0.0188494473695755,
-0.07975313812494278,
-0.012888088822364807,
0.09620222449302673,
-0.09906160086393356,
-0.05823875591158867,
-0.0037980321794748306,
-0.02916112169623375,
-0.019102830439805984,
0.03858162462711334,
-0.02311290055513382,
0.08446617424488068,
0.012766733765602112,
-0.0018512674141675234,
-0.0311470627784729,
-0.014835209585726261,
-0.04867338016629219,
-0.03679391369223595,
-0.02199026383459568,
-0.04506911337375641,
-0.008135433308780193,
0.01300486084073782,
-0.009916454553604126,
-0.040438730269670486,
-0.10096871107816696,
0.0396067351102829,
0.044944923371076584,
0.032168351113796234,
-0.015819787979125977,
-0.023288769647479057,
0.018682381138205528,
0.004155084025114775,
-0.07635554671287537,
0.025402560830116272,
0.005479025654494762,
-0.014445342123508453,
-0.02077333629131317,
-0.02018631063401699,
-0.0405573844909668,
-0.014305666089057922,
-0.058046288788318634,
0.04410315304994583,
-0.044125497341156006
] |
PMID:9457244 | (3) The potential importance of the hydrophobic group at position R3 as illustrated by its ability to impart greater relative potency against stromelysin when larger hydrophobic groups are used. | [
-0.05191529169678688,
-0.11282595247030258,
-0.025608235970139503,
-0.018616901710629463,
0.08001487702131271,
0.06911972910165787,
-0.021375957876443863,
0.0890614464879036,
0.025145556777715683,
-0.07413849979639053,
0.0004250424390193075,
0.016413221135735512,
-0.07842202484607697,
0.09426634758710861,
0.005463453941047192,
0.00608754251152277,
-0.040934644639492035,
0.10346397012472153,
-0.057708874344825745,
-0.04318124055862427,
0.019565926864743233,
-0.039873864501714706,
0.019306082278490067,
0.044320523738861084,
-0.05008622631430626,
0.0850013718008995,
-0.05663474649190903,
0.0436653308570385,
0.1274738311767578,
-0.05047863721847534,
-0.022921638563275337,
-0.00048033686471171677,
0.13244789838790894,
-0.11705303192138672,
-0.06997020542621613,
0.05930905044078827,
-0.06769156455993652,
-0.07983508706092834,
-0.005844349041581154,
0.047183528542518616,
-0.017637552693486214,
0.050016071647405624,
0.020965201780200005,
-0.014982843771576881,
-0.0064680129289627075,
-0.04972635582089424,
0.053874459117650986,
0.037659209221601486,
-0.03953438252210617,
0.02288862131536007,
0.028126701712608337,
-0.04383980482816696,
-0.07293649762868881,
0.014941995032131672,
-0.07898932695388794,
0.025836406275629997,
-0.1078212633728981,
-0.006392342504113913,
-0.018763115629553795,
0.00605727406218648,
0.050531428307294846,
0.04695890098810196,
0.05402418226003647,
0.0006279860972426832,
0.03049919568002224,
-0.04558460786938667,
0.029063256457448006,
-0.031132755801081657,
0.07874532788991928,
0.1017611101269722,
0.022883854806423187,
0.03215732425451279,
-0.025163989514112473,
0.019144201651215553,
0.008984480984508991,
0.07305596023797989,
-0.00029545274446718395,
-0.0028552960138767958,
-0.02780883200466633,
0.004382350016385317,
0.029497185721993446,
-0.011085419915616512,
0.02901299297809601,
0.16013121604919434,
0.026750126853585243,
-0.05042393505573273,
-0.0795845165848732,
-0.07190407067537308,
-0.03814488276839256,
-0.0248970128595829,
0.10456530749797821,
0.0234516728669405,
-0.07301580905914307,
0.020533202216029167,
-0.01001239474862814,
0.022375570610165596,
-0.017228107899427414,
-0.042412169277668,
-0.02924140729010105,
0.03622059151530266,
-0.025156989693641663,
-0.013787886127829552,
-0.017318185418844223,
0.034024130553007126,
0.06541147083044052,
-0.033058762550354004,
-0.02076995186507702,
-0.01518139149993658,
-0.0012415291275829077,
-0.010205398313701153,
-0.012365572154521942,
-0.025299200788140297,
0.012111332267522812,
0.04638015851378441,
-0.11934402585029602,
-0.029504088684916496,
0.007430065423250198,
-0.03166896849870682,
0.03548448532819748,
0.006728760432451963,
0.011268455535173416,
-0.0005232651601545513,
0.027213802561163902,
-0.04163603484630585,
0.012020437978208065,
-0.017740687355399132,
-0.044280700385570526,
1.2808010122407021e-33,
0.007502170279622078,
-0.003388206474483013,
-0.00007200031541287899,
-0.03061954490840435,
-0.012648455798625946,
-0.0627443715929985,
-0.05675714462995529,
-0.009402244351804256,
-0.004350373987108469,
0.01379172783344984,
-0.0325896292924881,
0.022746212780475616,
0.05531385913491249,
0.06996945291757584,
-0.0405074879527092,
-0.0009082253673113883,
-0.01681113988161087,
-0.011324227787554264,
0.02497735247015953,
-0.01621151715517044,
0.05286003649234772,
0.03194001689553261,
-0.05426730215549469,
-0.015079744160175323,
-0.02701643854379654,
-0.040550921112298965,
-0.04582015424966812,
0.029292525723576546,
0.029037712141871452,
0.028349634259939194,
0.0043755085207521915,
-0.033354684710502625,
-0.0916302353143692,
0.05344652011990547,
0.043504077941179276,
0.06010622903704643,
-0.05947302654385567,
-0.10328059643507004,
0.06334530562162399,
0.011321444064378738,
0.013748387806117535,
0.040942251682281494,
-0.0034049982205033302,
-0.0060508656315505505,
0.07999736815690994,
-0.012590336613357067,
0.002390103880316019,
0.0030539100989699364,
-0.07506116479635239,
0.020853199064731598,
0.021188996732234955,
0.026293421164155006,
0.025090491399168968,
0.029528770595788956,
0.01171860285103321,
-0.09310212731361389,
-0.021953081712126732,
0.07724897563457489,
-0.03131929412484169,
0.031327877193689346,
-0.06847023963928223,
0.03929063305258751,
-0.02071852795779705,
-0.001600746065378189,
0.016610056161880493,
0.06824936717748642,
-0.06625381857156754,
0.0010324011091142893,
0.04714275524020195,
-0.033518340438604355,
-0.0347692146897316,
0.0007570507004857063,
0.03562610596418381,
0.04696004092693329,
-0.03685915842652321,
-0.011957196518778801,
-0.02035350352525711,
0.04478874057531357,
0.06189124286174774,
0.014371042139828205,
-0.027163846418261528,
0.004347992595285177,
-0.05882006883621216,
0.005737113766372204,
-0.1684475690126419,
0.00890094693750143,
0.11554093658924103,
-0.04465401545166969,
0.03891157731413841,
0.013520446605980396,
0.1008877381682396,
-0.07467536628246307,
0.02358057349920273,
0.0003396466199774295,
0.0059423502534627914,
-3.719444123574187e-33,
-0.044063713401556015,
-0.05677644535899162,
0.01332567073404789,
0.0018076302949339151,
-0.04028487205505371,
0.025511030107736588,
0.07700905203819275,
-0.0683649331331253,
0.057445477694272995,
-0.026411933824419975,
0.06667795777320862,
0.09147324413061142,
-0.0701291486620903,
-0.042631298303604126,
-0.04332248866558075,
0.06648467481136322,
-0.04356871545314789,
-0.03516017273068428,
-0.059011057019233704,
-0.030319923534989357,
0.059198878705501556,
0.021979648619890213,
0.01003551296889782,
0.12523698806762695,
-0.014591434970498085,
0.0021999727468937635,
0.011365409009158611,
-0.1141962856054306,
0.009750946424901485,
0.07905347645282745,
-0.004028939642012119,
-0.040163554251194,
-0.09459302574396133,
-0.03385907784104347,
0.03931190446019173,
0.014630656689405441,
-0.028995182365179062,
0.05338674411177635,
0.011971864849328995,
-0.0534716360270977,
0.0684761330485344,
0.0036290884017944336,
0.04597743973135948,
0.010758519172668457,
0.10812879353761673,
0.1757889986038208,
0.005909656174480915,
0.0025623070541769266,
0.029412344098091125,
0.011171599850058556,
-0.04781518504023552,
0.017850179225206375,
0.008697913959622383,
0.024505818262696266,
0.035589709877967834,
-0.019681628793478012,
0.005219286307692528,
-0.08420049399137497,
-0.04207872226834297,
0.06936712563037872,
-0.044221825897693634,
-0.015200747177004814,
-0.046329595148563385,
-0.04508432373404503,
-0.07871391624212265,
-0.061158306896686554,
-0.0579865463078022,
0.09981473535299301,
0.13346506655216217,
-0.0550483800470829,
-0.021923892199993134,
-0.009129648096859455,
0.12914475798606873,
-0.029486581683158875,
-0.022516870871186256,
0.019970117136836052,
-0.009543652646243572,
-0.05969657376408577,
-0.08318261802196503,
-0.03724824637174606,
-0.011921584606170654,
0.053606417030096054,
-0.053737822920084,
0.008427388966083527,
0.03879779949784279,
-0.011932878755033016,
0.01982589066028595,
0.013152067549526691,
-0.008832111023366451,
-0.05459548905491829,
0.027180355042219162,
-0.057067785412073135,
-0.06422045081853867,
0.011091123335063457,
0.1311669647693634,
-3.174715956788532e-8,
0.048668477684259415,
-0.0489758662879467,
0.04252803325653076,
-0.05199157074093819,
-0.02451588585972786,
0.0725921019911766,
-0.06200633943080902,
0.0246565043926239,
-0.02012532390654087,
0.04105357080698013,
0.052255257964134216,
0.03692962974309921,
-0.025451015681028366,
-0.056482840329408646,
0.028983259573578835,
0.0459800623357296,
-0.0724184587597847,
-0.04742167890071869,
-0.018034135922789574,
-0.10208283364772797,
-0.039001237601041794,
-0.04376199096441269,
-0.03432655707001686,
0.011130024679005146,
0.012646200135350227,
0.024266013875603676,
0.02012435533106327,
-0.04100284352898598,
-0.08598729968070984,
-0.02099810168147087,
0.08333907276391983,
0.01944561116397381,
-0.031113388016819954,
0.11619999259710312,
0.09507843852043152,
0.06218305602669716,
-0.012464596889913082,
0.03507925942540169,
-0.05398618429899216,
-0.011918865144252777,
-0.02884683758020401,
-0.02744963765144348,
-0.04598775878548622,
0.0005280408659018576,
0.00669839046895504,
0.010036494582891464,
-0.013687935657799244,
0.07413540780544281,
-0.07891866564750671,
-0.01288744155317545,
0.018816573545336723,
-0.061088304966688156,
-0.06231142207980156,
0.05204871669411659,
-0.01117984764277935,
-0.02649647742509842,
-0.045140236616134644,
-0.05582941696047783,
-0.07351411134004593,
-0.01804056391119957,
-0.021461661905050278,
0.02030550129711628,
0.05525445565581322,
-0.04118310660123825
] |
PMID:9457244 | (4) Requirements surrounding the nature of the amino acid appear to be more restrictive for stromelysin than for neutrophil collagenase, 72 kDa gelatinase, and 92 kDa gelatinase. | [
-0.010738135315477848,
-0.09801691770553589,
-0.08756782114505768,
-0.07387036830186844,
-0.10848916321992874,
0.07122934609651566,
-0.11419677734375,
0.15461984276771545,
-0.0015902577433735132,
-0.018913354724645615,
0.0033011804334819317,
0.029418786987662315,
-0.0539708249270916,
0.12171664834022522,
-0.06534677743911743,
-0.0900791585445404,
0.022730685770511627,
0.024000944569706917,
-0.05551426112651825,
-0.07004093378782272,
0.021129004657268524,
0.022593403235077858,
-0.03258877992630005,
-0.07279950380325317,
0.019245950505137444,
-0.059948768466711044,
-0.04037357494235039,
-0.11055656522512436,
0.026897648349404335,
0.014775440096855164,
-0.012373130768537521,
-0.05111207067966461,
0.08642750233411789,
-0.03605733439326286,
0.10286172479391098,
-0.04834485426545143,
-0.0555560402572155,
-0.04723610356450081,
-0.018026338890194893,
0.07013292610645294,
0.014672383666038513,
0.0315995067358017,
-0.0023346482776105404,
0.033602070063352585,
-0.015770303085446358,
-0.0363088995218277,
0.060833126306533813,
0.0061472454108297825,
-0.015384706668555737,
0.051431622356176376,
-0.06797827780246735,
-0.044949449598789215,
-0.10057830810546875,
0.006320626009255648,
-0.04323595017194748,
0.010891854763031006,
-0.13253571093082428,
-0.02914617583155632,
0.025093959644436836,
0.06782201677560806,
-0.0023244020994752645,
-0.0028946262318640947,
0.05336040258407593,
-0.030226169154047966,
0.032355520874261856,
-0.04230838641524315,
0.07861737161874771,
-0.016924628987908363,
-0.007660274859517813,
0.058136824518442154,
0.048579927533864975,
0.02844647504389286,
-0.04318314790725708,
0.09296593070030212,
-0.01883666217327118,
0.005545047577470541,
-0.04372551292181015,
-0.004428963642567396,
0.0012973324628546834,
-0.021533487364649773,
0.04989759996533394,
-0.015411922708153725,
-0.01702692173421383,
0.06359423696994781,
0.06395381689071655,
0.023655708879232407,
-0.025293387472629547,
0.04134064540266991,
0.01672768034040928,
-0.00032771058613434434,
0.06229231879115105,
-0.08224105089902878,
-0.008329510688781738,
-0.024855146184563637,
0.01107092760503292,
-0.012495534494519234,
-0.02909422293305397,
0.0663827508687973,
-0.02504540979862213,
-0.014399968087673187,
-0.03730065003037453,
0.020713232457637787,
0.07683837413787842,
0.025853769853711128,
0.006128605455160141,
-0.020596858114004135,
-0.035743921995162964,
0.002300544176250696,
0.011125339195132256,
0.015887955203652382,
0.03130178898572922,
0.010294148698449135,
0.00945838913321495,
-0.03560983017086983,
0.024291308596730232,
0.03320946916937828,
0.09764687716960907,
-0.04748974367976189,
-0.016325751319527626,
0.07638391107320786,
-0.03553846478462219,
0.008789807558059692,
0.10436281561851501,
0.03477289900183678,
-0.020884063094854355,
0.022092312574386597,
-0.04281912371516228,
2.1148291314994927e-33,
-0.027323177084326744,
0.048241931945085526,
0.0494907945394516,
-0.024882791563868523,
-0.056878965348005295,
-0.00426078075543046,
-0.11992283910512924,
0.017698273062705994,
0.007501917891204357,
-0.008256442844867706,
-0.01856909692287445,
0.022096388041973114,
0.07826029509305954,
0.015550249256193638,
0.0008766415994614363,
0.08266919106245041,
0.0416092574596405,
-0.018959755077958107,
0.02349146269261837,
-0.025568528100848198,
0.06184663251042366,
0.033186912536621094,
-0.023668555542826653,
0.01915482059121132,
-0.0017448387807235122,
-0.029660962522029877,
-0.01933889277279377,
0.05046272277832031,
0.08051256835460663,
0.0033265664242208004,
-0.01933962292969227,
-0.07596371322870255,
-0.027172258123755455,
0.01352139376103878,
0.08137491345405579,
0.04934239014983177,
-0.12805098295211792,
-0.046478696167469025,
0.052413057535886765,
0.004510626196861267,
-0.037307724356651306,
0.006593972444534302,
-0.011983130127191544,
0.011026457883417606,
0.10095400363206863,
-0.005124123767018318,
0.021521572023630142,
0.023600930348038673,
-0.09526825696229935,
-0.015477948822081089,
0.031030826270580292,
0.029002584517002106,
0.024270247668027878,
0.011453503742814064,
0.03066725842654705,
-0.01419958658516407,
0.007851827889680862,
0.010865732096135616,
0.02177906222641468,
0.07785549759864807,
-0.01834719069302082,
-0.02088550478219986,
-0.020321713760495186,
-0.021084841340780258,
-0.042630694806575775,
0.012092696502804756,
-0.1171475350856781,
0.02534855157136917,
-0.050756752490997314,
0.007345867808908224,
-0.03899070620536804,
-0.05903492867946625,
-0.019134528934955597,
-0.00019527223776094615,
-0.012716754339635372,
-0.05672217532992363,
0.007817584089934826,
0.03851381316781044,
-0.00868804007768631,
-0.036531686782836914,
0.027570106089115143,
-0.012486997991800308,
-0.1275872439146042,
0.010088465176522732,
-0.09051093459129333,
-0.02721557393670082,
0.08147366344928741,
-0.004128807689994574,
0.044772226363420486,
0.04896300286054611,
0.11366789042949677,
-0.06247878447175026,
-0.09422659128904343,
0.06469128280878067,
0.08131428062915802,
-3.212465165008043e-33,
0.024313775822520256,
-0.07871396839618683,
-0.006402133032679558,
-0.04815606400370598,
0.026778724044561386,
0.010096938349306583,
0.1310887187719345,
-0.018814601004123688,
0.029379336163401604,
-0.040793098509311676,
0.13625872135162354,
0.003563743783161044,
-0.11612600088119507,
-0.03736063465476036,
-0.04529425501823425,
0.07183796167373657,
-0.015955200418829918,
0.04191124811768532,
0.012423486448824406,
-0.02969457395374775,
-0.04964855685830116,
0.0793832316994667,
-0.006748870015144348,
0.09332180768251419,
0.058235086500644684,
0.06783799082040787,
-0.08834705501794815,
0.004249271005392075,
0.006532256957143545,
0.04566079378128052,
-0.015190862119197845,
-0.06814564764499664,
-0.03540158271789551,
0.014514749869704247,
-0.06693565100431442,
0.016981085762381554,
0.0004761206218972802,
0.029155537486076355,
0.064954973757267,
-0.06143006682395935,
0.058456677943468094,
0.09391763061285019,
0.02093151956796646,
0.10129861533641815,
0.055682506412267685,
0.1066550463438034,
0.029556775465607643,
0.024290548637509346,
0.01645292527973652,
-0.05921030044555664,
0.004413829650729895,
-0.015467781573534012,
0.04028954356908798,
-0.015350395813584328,
0.025234220549464226,
-0.006131114903837442,
0.042729105800390244,
0.00477446336299181,
-0.06827545911073685,
-0.0017545390874147415,
-0.014890934340655804,
-0.0835181325674057,
0.012160181999206543,
-0.020958006381988525,
-0.008982175029814243,
-0.06676767766475677,
-0.05568650737404823,
0.0845593810081482,
-0.008557836525142193,
0.004217003006488085,
-0.10232739895582199,
-0.025733591988682747,
0.055815376341342926,
-0.03201350197196007,
-0.028520449995994568,
-0.05599113553762436,
-0.04403402656316757,
-0.0291169174015522,
-0.00445973128080368,
-0.11663837730884552,
-0.1448194980621338,
-0.03407582268118858,
0.023320384323596954,
0.044225867837667465,
0.045871663838624954,
-0.007964915595948696,
0.049801215529441833,
0.011577384546399117,
0.06971099972724915,
0.023496337234973907,
-0.02616177313029766,
-0.02860821969807148,
-0.053058236837387085,
0.06201295927166939,
0.07066886872053146,
-3.158235273303944e-8,
0.06263096630573273,
-0.004414718132466078,
-0.03541957587003708,
-0.0717855840921402,
0.032584741711616516,
-0.010142100043594837,
-0.07653675228357315,
-0.023749230429530144,
0.03755709528923035,
0.06501857936382294,
0.011261519975960255,
0.07431115955114365,
-0.06978797912597656,
0.017036795616149902,
-0.06377247720956802,
0.03394649177789688,
-0.07993894815444946,
-0.04419485852122307,
0.048955053091049194,
-0.04459046572446823,
-0.021295813843607903,
0.01605588011443615,
-0.04946214705705643,
0.06994006037712097,
-0.07108467817306519,
0.0030188069213181734,
0.008427181281149387,
0.06458090245723724,
-0.05608834698796272,
-0.008488651365041733,
0.038333065807819366,
-0.006433679722249508,
-0.035940058529376984,
-0.032186735421419144,
-0.004649600945413113,
-0.0010576802305877209,
0.04980406537652016,
-0.012804425321519375,
0.004684163257479668,
-0.01983611099421978,
0.06735390424728394,
-0.018012050539255142,
-0.02841774933040142,
0.04572494700551033,
0.04068246856331825,
0.01079841423779726,
0.09537003189325333,
0.01430206187069416,
-0.003753125201910734,
-0.015435772016644478,
-0.004913336597383022,
-0.007884098216891289,
-0.05651358142495155,
0.013914060778915882,
-0.03897961601614952,
0.011403550393879414,
-0.06720922142267227,
-0.04901936650276184,
-0.07667811214923859,
-0.010899857617914677,
-0.00890048872679472,
-0.04427366703748703,
0.12117230147123337,
-0.013433866202831268
] |
PMID:9457244 | These requirements may involve planar fused-ring aryl systems and possibly hydrogen-bonding capabilities. | [
-0.094183549284935,
-0.03798210248351097,
-0.09910061210393906,
-0.013701343908905983,
-0.09745641052722931,
-0.0680573433637619,
-0.043245021253824234,
0.056763168424367905,
-0.06576424092054367,
-0.08506643772125244,
0.0031274461653083563,
0.02734076976776123,
-0.06307365745306015,
0.007889511063694954,
0.06338995695114136,
0.001931933336891234,
-0.009736821986734867,
0.01957700587809086,
0.02571331150829792,
0.04834376648068428,
0.03967895358800888,
-0.011018325574696064,
-0.047822803258895874,
-0.039607807993888855,
-0.05637485533952713,
0.05809508636593819,
0.07102765887975693,
0.005030909087508917,
-0.05221427604556084,
-0.06804179400205612,
0.12456365674734116,
0.009580245241522789,
-0.04837195947766304,
-0.045199859887361526,
0.03843298181891441,
-0.010768609121441841,
-0.041395075619220734,
-0.03191128745675087,
0.00206926790997386,
-0.03152541443705559,
-0.027211306616663933,
-0.05600520223379135,
0.08624938875436783,
-0.006923781707882881,
-0.03366319462656975,
-0.02837943471968174,
0.011767955496907234,
0.002829708158969879,
-0.06572020798921585,
-0.09363917261362076,
0.0073343864642083645,
0.022554928436875343,
0.003668701509013772,
-0.02646554820239544,
-0.013582558371126652,
0.04728694632649422,
-0.10473857074975967,
-0.008581181988120079,
-0.05948903039097786,
-0.021106833592057228,
0.045175131410360336,
0.0039796228520572186,
-0.04711439460515976,
-0.02090085856616497,
-0.08979598432779312,
-0.0025596863124519587,
0.07336650788784027,
0.004120672587305307,
0.032491810619831085,
0.04822656884789467,
-0.021773776039481163,
-0.05809085816144943,
-0.08475492149591446,
-0.04697411507368088,
0.019277341663837433,
0.016564911231398582,
0.08150867372751236,
-0.05912729352712631,
0.06237819045782089,
0.035637132823467255,
-0.10702569782733917,
0.04218461364507675,
0.02110082283616066,
0.011524173431098461,
0.03735365718603134,
0.04094219207763672,
-0.05697081238031387,
-0.02195269800722599,
-0.13381357491016388,
-0.1189839094877243,
0.028508029878139496,
-0.01680678129196167,
0.006608276627957821,
-0.04804772883653641,
0.01634872704744339,
0.09862640500068665,
-0.0017535421065986156,
-0.08472451567649841,
0.010081283748149872,
0.0044890232384204865,
0.006495166569948196,
-0.026980508118867874,
-0.03732764348387718,
0.007059761323034763,
-0.048929378390312195,
0.02490897849202156,
-0.007501521147787571,
0.08287495374679565,
-0.00659958366304636,
-0.011959978379309177,
-0.021643606945872307,
-0.05616939812898636,
0.043289560824632645,
-0.08026374876499176,
-0.04495959356427193,
-0.039117053151130676,
-0.014470107853412628,
0.02255583554506302,
0.15120916068553925,
0.034105874598026276,
-0.022978881374001503,
0.04418511688709259,
-0.03593125194311142,
0.01031418051570654,
0.005098032299429178,
0.017590921372175217,
-0.07771503180265427,
3.7657184229670163e-34,
0.019861537963151932,
0.09045910835266113,
0.02450554631650448,
-0.01099714171141386,
-0.06553160399198532,
-0.016654735431075096,
-0.07164575904607773,
-0.04452306404709816,
0.04715295135974884,
-0.029095692560076714,
-0.015704702585935593,
-0.03348222374916077,
0.04486025497317314,
0.0637933760881424,
0.032025016844272614,
-0.03226214274764061,
0.03551473468542099,
0.061128295958042145,
0.009140659123659134,
0.0013249723706394434,
-0.08555147796869278,
0.024766895920038223,
0.05107908323407173,
0.05687927454710007,
0.04241117462515831,
0.005993242841213942,
0.10861773788928986,
-0.11275850236415863,
-0.013658900745213032,
-0.005488558206707239,
-0.015189112164080143,
0.045865003019571304,
0.01161518320441246,
0.0837133526802063,
0.016176417469978333,
0.11516046524047852,
-0.09873626381158829,
-0.042325519025325775,
0.011773276142776012,
-0.06257686018943787,
0.06310166418552399,
0.04487686976790428,
-0.03529063239693642,
-0.025206809863448143,
0.024562351405620575,
0.00029618016560561955,
0.008985205553472042,
0.10832405090332031,
-0.03902895003557205,
-0.0028136863838881254,
0.0349462665617466,
0.02953483723104,
0.014779639430344105,
0.07359270006418228,
0.11489059031009674,
0.010136265307664871,
-0.005080642644315958,
-0.039464738219976425,
0.08890239894390106,
0.0549943707883358,
-0.15999124944210052,
0.016090165823698044,
-0.045710619539022446,
0.009554160758852959,
0.01817166432738304,
0.0790449008345604,
-0.01201332826167345,
-0.06327078491449356,
-0.049717165529727936,
0.023114951327443123,
-0.024398837238550186,
0.008185635320842266,
0.048828162252902985,
0.028251277282834053,
-0.008780524134635925,
0.04149266704916954,
0.005230826325714588,
-0.0870731770992279,
0.09296709299087524,
0.07296359539031982,
-0.0631662905216217,
-0.008986731991171837,
0.043728411197662354,
-0.06889834254980087,
-0.01862422004342079,
-0.052253060042858124,
0.019388601183891296,
0.0513911135494709,
-0.0018072699895128608,
0.03701641410589218,
0.07523369789123535,
-0.09045560657978058,
0.010206200182437897,
-0.03887556120753288,
0.02113787643611431,
-1.4381352372975035e-33,
0.05255960300564766,
-0.05661572143435478,
-0.020796559751033783,
0.011303326115012169,
0.10483913123607635,
0.023874431848526,
0.025182954967021942,
-0.1213642805814743,
0.010504313744604588,
-0.03999490290880203,
0.04168682172894478,
0.017255155369639397,
0.06467495113611221,
-0.023481065407395363,
-0.013759874738752842,
-0.00607930077239871,
-0.03349629417061806,
-0.04174937680363655,
0.12680374085903168,
0.012178932316601276,
0.08093448728322983,
0.02569400519132614,
-0.02442803420126438,
0.046913325786590576,
-0.001891565159894526,
-0.047172367572784424,
-0.07375229895114899,
-0.10080260038375854,
0.0015101747121661901,
0.069655641913414,
0.018423957750201225,
-0.08615520596504211,
0.026280047371983528,
0.04041539505124092,
0.018110305070877075,
0.023784181103110313,
-0.0074984608218073845,
0.052309438586235046,
-0.03363708779215813,
-0.07133795320987701,
0.017598120495676994,
-0.04287141188979149,
-0.0017824576934799552,
0.04327636584639549,
0.012849465012550354,
0.005902495235204697,
-0.02460957132279873,
-0.0385541133582592,
-0.02218586951494217,
-0.06835564225912094,
-0.0335807204246521,
-0.05553128570318222,
0.005508527159690857,
-0.09206792712211609,
0.021147936582565308,
-0.03481195494532585,
0.06647475063800812,
-0.026724517345428467,
0.05178443342447281,
0.03166279196739197,
0.04189133271574974,
-0.03555051609873772,
0.11293265223503113,
-0.0489332489669323,
0.01614784449338913,
-0.02676461450755596,
0.03554490581154823,
-0.04533201456069946,
0.010051550343632698,
-0.03623829782009125,
0.09217601269483566,
0.05074126645922661,
0.1129668578505516,
0.08204293996095657,
0.03258711099624634,
-0.09141591191291809,
0.026013771072030067,
-0.07431121170520782,
0.06551652401685715,
0.043457064777612686,
-0.047866396605968475,
0.02525702305138111,
-0.0075353654101490974,
0.034746650606393814,
0.07744408398866653,
-0.06168759614229202,
-0.04349854588508606,
0.0070780422538518906,
0.050870493054389954,
0.030155640095472336,
0.05466940626502037,
0.05927029624581337,
0.09662327170372009,
0.07610537111759186,
-0.010082065127789974,
-2.397906939677341e-8,
0.08606822788715363,
-0.017689483240246773,
-0.04644057899713516,
-0.04073993116617203,
-0.0701540932059288,
0.03549908846616745,
0.06868407875299454,
-0.03796945884823799,
0.06738554686307907,
-0.05225098878145218,
0.03237064927816391,
0.002452433342114091,
0.015155486762523651,
0.046976327896118164,
0.0503702238202095,
-0.02558567188680172,
0.03881873935461044,
-0.028339808806777,
-0.04217527061700821,
-0.04497963935136795,
-0.026442741975188255,
0.031298357993364334,
-0.022189341485500336,
0.019344259053468704,
-0.0146351782605052,
-0.011271139606833458,
0.06782015413045883,
0.03477940708398819,
0.00913100503385067,
0.04130220040678978,
-0.01763766258955002,
-0.022477678954601288,
0.03455672040581703,
0.06385447084903717,
0.013122139498591423,
-0.01706170104444027,
-0.028853749856352806,
0.022187763825058937,
0.018220076337456703,
-0.023567182943224907,
-0.021397670730948448,
0.03127765655517578,
-0.03738541156053543,
0.004899919498711824,
0.061430126428604126,
0.0009427792392671108,
-0.07385877519845963,
-0.04878721386194229,
-0.08247856795787811,
0.026117639616131783,
0.0026541962288320065,
0.0584682822227478,
0.04144152253866196,
-0.010206366889178753,
-0.039059557020664215,
0.0855729803442955,
0.0025734659284353256,
0.026277795433998108,
0.04723067209124565,
-0.06419903039932251,
0.038870688527822495,
-0.007412854116410017,
0.04001529514789581,
0.05452066287398338
] |
PMID:19967559 | Breast cancer resistance protein (BCRP/ABCG2), an ATP-binding cassette half transporter, confers multidrug resistance (MDR) to a series of antitumor agents such as mitoxantrone, daunorubicin, SN-38, and topotecan, and often limits the efficacy of chemotherapy. | [
-0.05518166720867157,
-0.013314267620444298,
-0.048441216349601746,
-0.05455166473984718,
0.005978592671453953,
-0.002254594350233674,
-0.03218289092183113,
0.12248922139406204,
0.02347169630229473,
-0.06071322783827782,
-0.028703918680548668,
-0.06832610070705414,
0.05766510218381882,
0.018146440386772156,
-0.001143293920904398,
0.031242772936820984,
-0.05669170990586281,
0.02591562271118164,
0.050407249480485916,
0.014502255246043205,
-0.05509726330637932,
0.08711550384759903,
0.017273414880037308,
0.19541488587856293,
-0.01851421222090721,
-0.006744964048266411,
-0.034612931311130524,
0.06534034758806229,
-0.07104098051786423,
-0.031147995963692665,
0.02542007528245449,
-0.033811911940574646,
-0.04944240674376488,
0.0867384821176529,
-0.045615263283252716,
0.018936024978756905,
-0.014286170713603497,
0.063107930123806,
0.017754817381501198,
-0.02322216145694256,
0.024879010394215584,
-0.019817540422081947,
0.05272658169269562,
0.09700525552034378,
0.005421953741461039,
0.0017454802291467786,
-0.015827251598238945,
-0.01755129173398018,
0.06256692856550217,
0.10790032148361206,
-0.013289748691022396,
-0.00023539687390439212,
-0.051875125616788864,
0.08539985120296478,
0.1018226221203804,
-0.04877002537250519,
-0.061219170689582825,
0.04828832298517227,
0.025316867977380753,
-0.03964861109852791,
-0.03307291120290756,
-0.07929380238056183,
0.10759610682725906,
0.08719181269407272,
0.023321479558944702,
-0.014447321183979511,
-0.0790368989109993,
0.005331381689757109,
0.019206970930099487,
0.025988122448325157,
-0.05808933451771736,
-0.07601256668567657,
-0.022431300953030586,
0.026381012052297592,
0.021772941574454308,
-0.038000501692295074,
0.014162442646920681,
0.017420081421732903,
0.0017170434584841132,
0.019045352935791016,
-0.01638755202293396,
-0.027583880349993706,
0.033390823751688004,
0.11708460003137589,
0.0011187754571437836,
-0.08082789927721024,
0.031198663637042046,
-0.01256540883332491,
-0.024005917832255363,
-0.025949178263545036,
0.06061138957738876,
0.07952011376619339,
-0.009273745119571686,
0.039582036435604095,
-0.1174628883600235,
-0.02131897583603859,
-0.06813850998878479,
0.027776772156357765,
-0.08089424669742584,
0.012874440290033817,
0.03461091220378876,
0.022502508014440536,
-0.017809994518756866,
-0.07699642330408096,
-0.009701856411993504,
-0.07759732007980347,
0.054236557334661484,
-0.04507504031062126,
-0.02756168320775032,
0.01595339924097061,
0.07406056672334671,
0.022374343127012253,
0.046042561531066895,
0.02524295449256897,
0.010181008838117123,
0.0218040831387043,
-0.014680617488920689,
-0.049876920878887177,
-0.019168611615896225,
-0.029051268473267555,
-0.06981349736452103,
-0.10781866312026978,
0.04877302050590515,
-0.06812781095504761,
0.02846619114279747,
-0.007508709095418453,
-0.01152485515922308,
2.339486489421779e-33,
-0.005167808849364519,
-0.041142117232084274,
0.10862704366445541,
0.03656540811061859,
0.004336933605372906,
-0.0433373861014843,
0.010134666226804256,
-0.028611479327082634,
-0.02803844027221203,
-0.07209982722997665,
-0.07711538672447205,
-0.023600365966558456,
-0.02133280783891678,
0.03581209108233452,
-0.001917512621730566,
-0.085618756711483,
-0.06016581505537033,
-0.006921245250850916,
0.03508515655994415,
-0.0894731804728508,
0.02105827070772648,
0.01871129311621189,
-0.03293704614043236,
-0.01903267577290535,
0.04251343011856079,
0.0965193659067154,
-0.0720178559422493,
0.03745633363723755,
0.05334381386637688,
0.006524793803691864,
-0.043364353477954865,
0.004207223188132048,
-0.03675517439842224,
0.049345288425683975,
-0.032993994653224945,
-0.06316759437322617,
-0.04460680112242699,
-0.011770235374569893,
0.03702961280941963,
0.08886238187551498,
-0.10147988051176071,
-0.04225301370024681,
0.03174886107444763,
-0.022671448066830635,
0.06217823177576065,
-0.04548512026667595,
-0.03347253054380417,
-0.017718542367219925,
-0.05349981039762497,
0.007672138512134552,
0.05292387679219246,
-0.17038285732269287,
-0.014741399325430393,
0.03505605459213257,
0.03295968100428581,
-0.04477958008646965,
-0.1000857949256897,
0.051525842398405075,
-0.024049410596489906,
0.06969166547060013,
0.0259383711963892,
0.03718176111578941,
-0.03348538652062416,
0.03214697912335396,
-0.006098760291934013,
-0.029631588608026505,
-0.015455115586519241,
-0.06989436596632004,
-0.0129085099324584,
0.04325257986783981,
0.03703897446393967,
-0.004233782645314932,
0.07084882259368896,
0.026869408786296844,
0.02820436656475067,
0.07875344902276993,
-0.008740469813346863,
0.04160456359386444,
0.07153784483671188,
0.0983489528298378,
-0.0679812878370285,
-0.0876084640622139,
-0.07713194191455841,
0.03251917287707329,
-0.048797931522130966,
-0.054083943367004395,
0.06416104733943939,
-0.10987911373376846,
0.01602931320667267,
-0.018551133573055267,
0.032868970185518265,
-0.05065666884183884,
-0.027424857020378113,
0.014775009825825691,
0.007256748620420694,
-2.8890381799548602e-33,
0.08918170630931854,
-0.03973759710788727,
0.17600615322589874,
-0.03250288590788841,
-0.02894565649330616,
-0.01715925522148609,
0.012273121625185013,
-0.05510581657290459,
0.08435297012329102,
-0.00011816552432719618,
0.06360012292861938,
-0.021493863314390182,
0.02044510655105114,
-0.004256058484315872,
-0.003354444866999984,
-0.046305011957883835,
0.02268529124557972,
-0.050302907824516296,
-0.06313470751047134,
-0.03591061383485794,
0.011490192264318466,
0.07963817566633224,
-0.04988902434706688,
0.03397343307733536,
-0.09287375211715698,
0.05190249904990196,
0.030525662004947662,
0.028836147859692574,
0.10225722938776016,
0.049429986625909805,
-0.04005485028028488,
0.08171695470809937,
-0.03899553045630455,
-0.06042734161019325,
-0.045172207057476044,
0.0432373471558094,
-0.03685993701219559,
0.026092806831002235,
-0.018822448328137398,
-0.03505595773458481,
0.018259117379784584,
0.04382253810763359,
-0.04872554540634155,
0.01595868170261383,
0.034559499472379684,
0.029249485582113266,
0.01066559087485075,
0.043775733560323715,
0.04063025489449501,
-0.03579220548272133,
0.014112772420048714,
-0.022835033014416695,
0.03796147182583809,
0.04736984521150589,
0.07103151082992554,
0.024443665519356728,
-0.03580087050795555,
-0.04678100720047951,
0.03406834974884987,
-0.014487515203654766,
-0.033546555787324905,
-0.02993999794125557,
-0.028944190591573715,
-0.07784957438707352,
-0.007532049901783466,
0.09562104195356369,
-0.06897635757923126,
-0.041297975927591324,
0.07749643921852112,
0.0693766176700592,
0.10224268585443497,
0.03294402360916138,
0.033023182302713394,
0.014598540961742401,
-0.04248109459877014,
0.04898308217525482,
-0.018416868522763252,
-0.021812589839100838,
0.013498865999281406,
0.001880593248642981,
-0.0327688567340374,
0.04156654328107834,
0.014296266250312328,
-0.03690516576170921,
0.0037773004733026028,
0.012330583296716213,
-0.022445885464549065,
-0.030891969799995422,
-0.05103597790002823,
0.0015169816324487329,
-0.055907681584358215,
0.026351187378168106,
0.03899222984910011,
0.09827978909015656,
-0.09786723554134369,
-3.322196562294266e-8,
-0.00962483137845993,
-0.08580039441585541,
0.07069678604602814,
-0.11249161511659622,
0.004463993012905121,
0.06161677464842796,
-0.02994682639837265,
-0.009704099036753178,
0.021855559200048447,
0.029618598520755768,
0.031283698976039886,
0.09248422831296921,
0.01865548826754093,
-0.041202835738658905,
0.0034700948745012283,
0.06165383756160736,
0.06202806159853935,
-0.013940044678747654,
-0.019679132848978043,
-0.060239266604185104,
-0.05521383136510849,
-0.04992453381419182,
-0.00786504801362753,
0.010596989654004574,
-0.015002667903900146,
0.0039893994107842445,
0.03641604259610176,
0.04540760815143585,
0.030436471104621887,
-0.05453484132885933,
0.036925703287124634,
-0.04724087193608284,
0.017037315294146538,
0.04482274502515793,
-0.0027064017485827208,
0.042629580944776535,
-0.013810688629746437,
-0.05195976793766022,
0.042225953191518784,
0.059801243245601654,
0.022535013034939766,
-0.10513773560523987,
-0.01598556526005268,
0.008580691181123257,
-0.03865282982587814,
0.008351216092705727,
-0.0024992467369884253,
0.048765622079372406,
-0.09083177149295807,
-0.08203450590372086,
0.02387305162847042,
-0.03846360743045807,
0.016017217189073563,
-0.0022886954247951508,
-0.018022295087575912,
0.03045068122446537,
-0.019301550462841988,
0.03236314281821251,
0.03648398816585541,
-0.008033208549022675,
-0.053856123238801956,
-0.04488487169146538,
0.12456221133470535,
0.012585747055709362
] |
PMID:19967559 | Recent studies have indicated that a putative estrogen response element (ERE) is located in the promoter region of the BCRP gene. | [
-0.08354640007019043,
-0.008680467493832111,
-0.03905882686376572,
0.026496646925807,
0.02360619232058525,
0.03545982390642166,
0.06040153652429581,
0.06101918965578079,
0.03234102576971054,
-0.03435651585459709,
0.024304358288645744,
-0.10223714262247086,
-0.05566190183162689,
-0.06476752460002899,
0.096900574862957,
0.057558368891477585,
-0.04528338834643364,
-0.002834114246070385,
0.027254508808255196,
-0.012056218460202217,
0.028753994032740593,
0.08473346382379532,
-0.006077744998037815,
0.05850280076265335,
-0.03484732657670975,
-0.044466935098171234,
0.062420476227998734,
0.05143768712878227,
-0.011751268059015274,
-0.09035339206457138,
-0.007732813246548176,
-0.05858467519283295,
0.04954857751727104,
0.03588692098855972,
0.013145935721695423,
0.005537407007068396,
-0.019244307652115822,
-0.0556621178984642,
0.03335181251168251,
0.046627797186374664,
0.030477464199066162,
-0.00033819000236690044,
0.02066868543624878,
0.0031970564741641283,
0.038900528103113174,
0.0653863474726677,
0.037852562963962555,
-0.01726808212697506,
-0.021207574754953384,
0.0052000232972204685,
0.04978116601705551,
-0.09151319414377213,
0.028670456260442734,
0.05036161094903946,
-0.013299555517733097,
-0.01621876284480095,
0.04664164036512375,
-0.05227774381637573,
0.06990278512239456,
0.0070135341957211494,
0.03445231914520264,
-0.018805744126439095,
0.016210908070206642,
0.02455104887485504,
0.020419543609023094,
0.038737475872039795,
0.023252300918102264,
-0.07086516916751862,
-0.030164314433932304,
-0.10914087295532227,
-0.028119254857301712,
-0.08194157481193542,
-0.12346318364143372,
0.10994657129049301,
0.05053294450044632,
0.07803215086460114,
0.013010959140956402,
0.007528907153755426,
0.014529665000736713,
0.010180403478443623,
0.017238739877939224,
0.025748655200004578,
0.09254707396030426,
0.07962588220834732,
-0.02336311712861061,
-0.03598366677761078,
-0.02341410331428051,
-0.015438199043273926,
-0.02313440479338169,
0.06824997812509537,
0.0039117527194321156,
-0.06372001022100449,
-0.017089882865548134,
0.022302672266960144,
-0.0035707273054867983,
0.04232633858919144,
-0.0645698830485344,
-0.02946617640554905,
-0.0012500188313424587,
-0.023231878876686096,
-0.029730964452028275,
0.08642242103815079,
-0.10574408620595932,
0.021444277837872505,
-0.1068553626537323,
-0.01767089031636715,
0.07363033294677734,
0.0034950736444443464,
-0.012567547149956226,
-0.019458163529634476,
-0.017806658521294594,
-0.02857605554163456,
0.04226601868867874,
0.043477680534124374,
0.00004941138831782155,
-0.05005868151783943,
0.0034704552963376045,
0.060939252376556396,
0.0207777451723814,
-0.1289430409669876,
-0.0005197214195504785,
-0.010347273200750351,
0.03689919039607048,
0.0030259054619818926,
-0.0052942936308681965,
-0.05309438705444336,
-0.10766229033470154,
-1.0364327262715378e-33,
0.04333964362740517,
0.03469253331422806,
-0.0018405730370432138,
0.013891279697418213,
-0.07492197304964066,
0.12729616463184357,
0.0048896498046815395,
-0.061029788106679916,
-0.010357298888266087,
-0.12658359110355377,
-0.05804845318198204,
-0.022470714524388313,
-0.04122067615389824,
-0.03287757560610771,
-0.028849054127931595,
-0.02988341823220253,
0.0003522150800563395,
0.1083565503358841,
-0.0186120867729187,
-0.072764553129673,
-0.005191665142774582,
0.037979740649461746,
-0.026031646877527237,
-0.10059468448162079,
0.01825091242790222,
0.011561384424567223,
-0.029344668611884117,
0.0021346197463572025,
-0.04181818291544914,
-0.03035900928080082,
-0.06682030111551285,
-0.013458242639899254,
0.016531439498066902,
0.058498088270425797,
0.08816273510456085,
-0.03951135277748108,
0.04017239063978195,
-0.0007639784016646445,
-0.0013140063965693116,
0.09803558140993118,
0.007289936766028404,
0.049485381692647934,
0.0029613161459565163,
0.013873254880309105,
-0.007841958664357662,
-0.09069642424583435,
-0.06371307373046875,
0.004257381893694401,
0.08921767771244049,
0.0191030353307724,
-0.07499206066131592,
0.018814992159605026,
0.07785645872354507,
-0.021750638261437416,
-0.0032654330134391785,
0.017766447737812996,
-0.060833889991045,
0.036872878670692444,
-0.022415488958358765,
-0.04078945145010948,
0.03825514391064644,
0.11353448778390884,
0.018211906775832176,
-0.03838752955198288,
-0.008651153184473515,
0.012044931761920452,
-0.0008587957127019763,
-0.01880715787410736,
-0.03124810755252838,
0.05238155648112297,
0.05643906071782112,
-0.01362108439207077,
0.13619138300418854,
0.015775147825479507,
-0.04154682904481888,
-0.019027769565582275,
-0.09788301587104797,
0.10022780299186707,
-0.025325961410999298,
-0.008068781346082687,
-0.04025334492325783,
-0.08058314770460129,
-0.13113874197006226,
0.060530729591846466,
0.07756591588258743,
-0.017614170908927917,
0.055830806493759155,
-0.025336410850286484,
-0.024643123149871826,
-0.01076952088624239,
0.03682079166173935,
-0.03862447291612625,
-0.06536953151226044,
0.0445086695253849,
0.0064613958820700645,
2.8197377370215977e-34,
0.044731505215168,
-0.053077325224876404,
0.0640348345041275,
-0.06774691492319107,
-0.002366633154451847,
-0.024046584963798523,
0.13688331842422485,
-0.00654855789616704,
0.05976150929927826,
0.04430633783340454,
0.08541776239871979,
-0.010335853323340416,
-0.03421707823872566,
0.023032955825328827,
0.03376856446266174,
-0.02728489227592945,
-0.03881625086069107,
0.047260574996471405,
-0.030300874263048172,
-0.09705149382352829,
-0.030833330005407333,
-0.029785897582769394,
0.0272974893450737,
0.05562799423933029,
0.027149170637130737,
0.03359988331794739,
0.01805134303867817,
0.05476076155900955,
-0.008662707172334194,
-0.005363818258047104,
-0.1049751341342926,
0.07522889226675034,
-0.05200175195932388,
-0.03681274130940437,
0.0010396672878414392,
0.028928913176059723,
-0.04446657374501228,
-0.010526604019105434,
0.006686059292405844,
-0.09018049389123917,
-0.005628381390124559,
0.080488421022892,
-0.06809410452842712,
0.014812150970101357,
0.08008360862731934,
0.09883084148168564,
0.08912200480699539,
0.058039385825395584,
0.046625252813100815,
0.027872662991285324,
-0.0335565060377121,
-0.03251445293426514,
0.029332930222153664,
-0.029520448297262192,
-0.05389941483736038,
-0.05173589661717415,
0.032856740057468414,
0.031051523983478546,
-0.04117729887366295,
-0.02691914699971676,
-0.012012052349746227,
0.059359628707170486,
0.04326261952519417,
0.007841657847166061,
-0.022993337363004684,
0.053522005677223206,
0.0076436931267380714,
-0.029750840738415718,
0.01790579780936241,
0.014034261927008629,
0.09557373821735382,
-0.04596826434135437,
0.0004208744503557682,
0.0547499880194664,
-0.0382278747856617,
-0.025789424777030945,
-0.019450662657618523,
-0.029424693435430527,
0.03959212452173233,
-0.0011974454391747713,
-0.051331546157598495,
0.04214650020003319,
-0.027693381533026695,
0.0011191627709195018,
0.0678524374961853,
-0.02078627608716488,
-0.059021297842264175,
0.028436431661248207,
0.03442752733826637,
-0.0008268785895779729,
-0.07660683244466782,
0.011283498257398605,
-0.0029421383515000343,
0.06258735060691833,
-0.03289731964468956,
-2.524229358868979e-8,
-0.00977180153131485,
-0.053793761879205704,
0.06603263318538666,
-0.05142173543572426,
0.06575783342123032,
-0.03470519557595253,
-0.0034127358812838793,
-0.014698776416480541,
0.0083339037373662,
-0.09640076756477356,
-0.028459757566452026,
0.04911297932267189,
-0.010095442645251751,
-0.058645159006118774,
0.10944917052984238,
0.0029181414283812046,
-0.002738828770816326,
0.051056649535894394,
-0.004351113457232714,
-0.07325240224599838,
0.0611976757645607,
-0.06103184074163437,
0.031082361936569214,
-0.0020865865517407656,
0.0027066818438470364,
0.03239743784070015,
0.06749396026134491,
0.05571703612804413,
0.00043887601350434124,
-0.07949831336736679,
0.13139823079109192,
-0.080707848072052,
0.032693345099687576,
0.025722529739141464,
0.028234554454684258,
0.07832982391119003,
-0.020229395478963852,
-0.0031652410980314016,
-0.02304668538272381,
0.0031795150134712458,
-0.06290382891893387,
-0.10069721192121506,
0.049583494663238525,
0.015342673286795616,
-0.011265480890870094,
0.0638665109872818,
-0.013324545696377754,
0.08159441500902176,
0.014135454781353474,
-0.08901975303888321,
-0.055985864251852036,
-0.08765576779842377,
-0.004434430040419102,
0.013723719865083694,
-0.07978755980730057,
-0.019539156928658485,
0.006698882207274437,
-0.05358843877911568,
0.08193281292915344,
0.034934353083372116,
0.009625274688005447,
0.021039707586169243,
0.13066251575946808,
-0.02701212279498577
] |
PMID:19967559 | However, whether and how BCRP is regulated transcriptionally by toremifene (TOR) remains unknown. | [
-0.12581852078437805,
-0.01118174847215414,
-0.11155140399932861,
-0.0568917840719223,
-0.017331911250948906,
0.025333836674690247,
-0.04521091282367706,
0.0804639607667923,
-0.017388105392456055,
-0.00006297372601693496,
0.0080906692892313,
-0.040759045630693436,
0.027691638097167015,
0.050857674330472946,
-0.02186434343457222,
0.02424306981265545,
-0.07166584581136703,
0.08585336804389954,
-0.02624390460550785,
-0.04593462869524956,
0.03867557644844055,
0.09590218961238861,
-0.004602754954248667,
0.07285868376493454,
-0.0029933422338217497,
-0.00961292628198862,
0.019511280581355095,
0.043195225298404694,
0.0020157480612397194,
-0.05227082222700119,
-0.019407672807574272,
0.0012421184219419956,
-0.03443276882171631,
0.01731036603450775,
0.08409108966588974,
0.03566907346248627,
-0.061692070215940475,
0.0016216278309002519,
0.03231658786535263,
0.0009747282019816339,
0.06464183330535889,
-0.043267399072647095,
-0.025605078786611557,
0.005574984475970268,
0.05150448530912399,
0.03719532489776611,
0.010604588314890862,
0.08275225013494492,
-0.05369033291935921,
0.008447851985692978,
-0.03584560751914978,
0.01581374742090702,
-0.005442481487989426,
0.12825383245944977,
-0.04245898872613907,
-0.05270855873823166,
-0.04331999272108078,
0.026173844933509827,
0.03793118894100189,
0.009668209590017796,
-0.02679901197552681,
-0.018240023404359818,
-0.017437944188714027,
0.03863157704472542,
0.04402166232466698,
0.05670703575015068,
0.009209142997860909,
-0.033462729305028915,
0.08758243918418884,
-0.10536742955446243,
-0.006174798589199781,
-0.06295609474182129,
-0.006331717129796743,
0.07254239916801453,
0.06866209208965302,
0.05085601657629013,
0.010755916126072407,
0.016620628535747528,
-0.035336486995220184,
-0.0573764406144619,
0.02472781017422676,
-0.04175807908177376,
0.09236014634370804,
0.1028454452753067,
-0.0060615455731749535,
0.011590573936700821,
0.024664998054504395,
-0.016513878479599953,
-0.0455806590616703,
0.08337634056806564,
0.10533607006072998,
-0.03452010825276375,
0.010188131593167782,
-0.019816456362605095,
-0.03939805552363396,
0.05973510444164276,
-0.027937838807702065,
0.042240552604198456,
-0.03377307578921318,
-0.00688079372048378,
-0.09464962035417557,
-0.08142970502376556,
-0.16081847250461578,
-0.035850152373313904,
-0.04087810963392258,
-0.07219146192073822,
0.07551933079957962,
0.059026893228292465,
0.07506746053695679,
0.028623931109905243,
0.03464658558368683,
0.005166609771549702,
0.07350333780050278,
0.026170825585722923,
-0.003610612591728568,
-0.015252874232828617,
0.009045569226145744,
0.028172144666314125,
-0.001268516993150115,
-0.0005903675919398665,
0.00006384774314938113,
-0.015644175931811333,
-0.03619830310344696,
-0.05515221878886223,
-0.06702207028865814,
0.03838766738772392,
-0.018165672197937965,
-1.0329732831312663e-33,
0.08997625857591629,
0.06322930753231049,
0.048406727612018585,
0.03700338304042816,
-0.13578829169273376,
0.07465968281030655,
-0.05391855165362358,
-0.05195655673742294,
-0.022736813873052597,
-0.06465799361467361,
-0.0877605751156807,
-0.03543264791369438,
-0.024889321997761726,
0.019870998337864876,
-0.06576617807149887,
-0.030842797830700874,
-0.04990249127149582,
0.04190834239125252,
0.040470827370882034,
-0.06899955123662949,
0.07894445955753326,
0.054998576641082764,
-0.003918628208339214,
-0.16311442852020264,
0.003512812778353691,
0.0064992355182766914,
0.00454489141702652,
-0.04219082370400429,
0.042805008590221405,
0.02614128403365612,
-0.05191861838102341,
0.03753989562392235,
-0.08658182621002197,
0.04597422108054161,
0.09222739934921265,
-0.03828135132789612,
0.03745143115520477,
-0.07013901323080063,
-0.04515914246439934,
0.06356298178434372,
0.003553609596565366,
0.01425436045974493,
0.007903773337602615,
-0.07471712678670883,
0.04812231287360191,
-0.12438739091157913,
-0.03430643305182457,
-0.048019178211688995,
-0.024361345916986465,
0.04602745175361633,
0.05071968212723732,
0.020481878891587257,
0.07247036695480347,
-0.0652766302227974,
0.04981489107012749,
0.010173455812036991,
-0.0652008056640625,
-0.08807498961687088,
0.028477223590016365,
0.038646165281534195,
0.03379526734352112,
0.08018076419830322,
-0.008143694140017033,
-0.03831469267606735,
0.04233400896191597,
0.015740955248475075,
-0.04656671732664108,
-0.03874901682138443,
-0.04267758131027222,
-0.04163014888763428,
-0.012635127641260624,
-0.024319076910614967,
0.07185068726539612,
-0.02323552779853344,
-0.03427834436297417,
-0.027811473235487938,
-0.05432599037885666,
0.11714842170476913,
0.05220310389995575,
-0.04317943751811981,
-0.005243751686066389,
-0.11210867762565613,
-0.00576636241748929,
0.09453712403774261,
0.024539481848478317,
-0.03110695257782936,
0.0108786690980196,
-0.06497309356927872,
-0.04855313152074814,
-0.00024538690922781825,
0.028976190835237503,
-0.027177171781659126,
-0.10580133646726608,
0.04069485142827034,
-0.020524300634860992,
3.7224570166143906e-34,
-0.023395415395498276,
-0.023582858964800835,
0.06266587972640991,
-0.02566961757838726,
-0.10678855329751968,
-0.040977854281663895,
-0.01414454821497202,
-0.020792923867702484,
0.08179827034473419,
0.006766456179320812,
0.10490608960390091,
0.013633823953568935,
-0.027327019721269608,
-0.01645519770681858,
-0.0167431328445673,
0.0009209146373905241,
0.008534527383744717,
0.037122514098882675,
-0.031642038375139236,
-0.00752727035433054,
-0.05290617048740387,
-0.03538081422448158,
-0.10445228964090347,
0.0911390483379364,
0.05470721796154976,
0.02126113884150982,
0.03008227050304413,
0.1005363017320633,
0.08885150402784348,
0.004425821825861931,
0.024475548416376114,
0.0442274808883667,
-0.07766430824995041,
-0.03660307452082634,
-0.02097659558057785,
0.041821252554655075,
0.012833289802074432,
0.029213400557637215,
0.009800138883292675,
-0.09890441596508026,
0.026835205033421516,
0.0370948500931263,
-0.08771122246980667,
-0.022338053211569786,
0.07635199278593063,
0.020818227902054787,
0.03397737815976143,
0.06810001283884048,
0.05136860907077789,
0.07099425047636032,
0.10991960018873215,
0.008946370333433151,
0.04547370970249176,
-0.017624016851186752,
0.00047212070785462856,
-0.042049840092659,
-0.002998270792886615,
-0.01059003546833992,
-0.04657778516411781,
-0.08442199975252151,
0.032219406217336655,
0.013346035964787006,
0.013252822682261467,
-0.03517390042543411,
0.06993597000837326,
0.07254023849964142,
-0.041969090700149536,
-0.026252105832099915,
0.04102899879217148,
-0.018889138475060463,
0.09256055951118469,
-0.06295117735862732,
0.03771130368113518,
-0.10263027250766754,
-0.002445115242153406,
-0.020342890173196793,
-0.0584627240896225,
-0.07727334648370743,
-0.014241191558539867,
0.015431642532348633,
0.0012860898859798908,
-0.01468317024409771,
0.045273762196302414,
-0.04651941731572151,
0.061480410397052765,
0.01821935549378395,
-0.020311087369918823,
-0.02574983797967434,
0.02491643838584423,
-0.0022380813024938107,
-0.06326061487197876,
0.0010579508962109685,
-0.010696202516555786,
0.060888711363077164,
0.016664164140820503,
-2.0553118318389352e-8,
0.08915407210588455,
0.0045615597628057,
0.007227621041238308,
-0.015939362347126007,
0.0038140560500323772,
0.017992915585637093,
0.03527344763278961,
-0.0286434143781662,
0.02822655253112316,
-0.009505619294941425,
0.013243000954389572,
-0.010105079039931297,
0.011895710602402687,
0.004090297035872936,
0.08978038281202316,
0.0597076453268528,
-0.003894528839737177,
-0.024301443248987198,
-0.02581877075135708,
0.006063569337129593,
-0.017800703644752502,
-0.052187882363796234,
-0.003069582162424922,
0.07382361590862274,
0.0008494104840792716,
-0.05230218172073364,
0.08310141414403915,
-0.018495889380574226,
0.040614426136016846,
-0.0036320677027106285,
0.07976280897855759,
-0.07947036623954773,
0.02996799349784851,
0.024242224171757698,
-0.07624208927154541,
0.06785625219345093,
-0.04009145870804787,
-0.028530601412057877,
-0.012393375858664513,
0.06120029836893082,
-0.009647776372730732,
-0.030794667080044746,
-0.02736521326005459,
0.043987005949020386,
0.043923527002334595,
-0.03557557985186577,
0.03603006899356842,
0.06781882792711258,
-0.07427859306335449,
-0.06335160881280899,
0.06062614917755127,
0.0023052741307765245,
0.02694174461066723,
-0.020349668338894844,
-0.0057001118548214436,
0.05458603426814079,
0.03768590837717056,
-0.030208580195903778,
0.05526461824774742,
0.002488532802090049,
-0.03788365051150322,
-0.011112975887954235,
0.10864720493555069,
-0.034055717289447784
] |
PMID:19967559 | In the present study, two plasmid vectors have been designed to express the wild-type full-length BCRP cDNA enforced driven by its endogenous promoter containing a functional ERE and a constitutive cytomegalovirus (CMV) promoter as control, respectively, which were transfected into estrogen-responsive MCF-7 and estrogen-independent MDA-MB-231 human breast adenocarcinoma cell lines. | [
-0.05122996121644974,
-0.061863016337156296,
-0.000123635443742387,
-0.05308040603995323,
-0.014206957072019577,
0.02739373780786991,
-0.03049042820930481,
0.03883948549628258,
-0.03886815160512924,
0.03801528364419937,
-0.05836360901594162,
-0.05530822277069092,
0.008632883429527283,
-0.000980973243713379,
0.03824286162853241,
0.0902346596121788,
-0.11043713986873627,
0.05561639741063118,
0.0660175085067749,
0.05568872392177582,
0.039492011070251465,
0.061195872724056244,
0.029877910390496254,
0.08264128118753433,
-0.05776125192642212,
-0.018950168043375015,
0.07769033312797546,
0.055437441915273666,
0.012081021443009377,
-0.03942779824137688,
-0.02525469847023487,
-0.046833738684654236,
0.025227436795830727,
0.041246283799409866,
-0.015629781410098076,
-0.004701743368059397,
-0.04630078375339508,
0.02205212228000164,
-0.06705155968666077,
0.027992187067866325,
0.05499470978975296,
0.051505349576473236,
-0.012666511349380016,
0.061685413122177124,
0.03392888233065605,
-0.026285827159881592,
0.02651061862707138,
-0.007103137671947479,
-0.027898190543055534,
-0.001503257779404521,
0.09877584874629974,
-0.035273708403110504,
-0.07683399319648743,
0.017907053232192993,
0.021263062953948975,
-0.06600315868854523,
-0.06097889319062233,
-0.05594431981444359,
0.10211940109729767,
-0.003942566458135843,
0.020041458308696747,
-0.005117872264236212,
0.06156124919652939,
0.02535577490925789,
0.001463379361666739,
-0.06217354163527489,
-0.05868012085556984,
0.018708664923906326,
-0.024231666699051857,
-0.018038645386695862,
-0.021057218313217163,
-0.059904079884290695,
-0.11795561760663986,
0.042445212602615356,
0.0653299018740654,
0.09825092554092407,
0.10604792088270187,
0.0037724552676081657,
0.03732379153370857,
0.010488053783774376,
-0.01847105287015438,
-0.010184640996158123,
0.09511061757802963,
-0.022115280851721764,
-0.016782188788056374,
-0.04083836451172829,
-0.03866681084036827,
0.019242649897933006,
0.004933226853609085,
0.05584697052836418,
0.08167190849781036,
0.004423358011990786,
0.08683203905820847,
-0.007223221007734537,
0.0029159511905163527,
0.01839708723127842,
-0.07140219956636429,
-0.02879202924668789,
0.020888451486825943,
-0.019338363781571388,
-0.05118134617805481,
0.01772073656320572,
-0.06370007991790771,
-0.0012612856226041913,
-0.03756467625498772,
-0.04687328264117241,
0.08124871551990509,
0.02569117769598961,
-0.050447605550289154,
0.0014717912999913096,
0.024760693311691284,
0.03182464838027954,
-0.0046507506631314754,
0.00004297893610782921,
-0.034222330898046494,
0.010911419056355953,
-0.06605243682861328,
0.021107284352183342,
0.08765775710344315,
-0.11599655449390411,
-0.04142102226614952,
-0.09286278486251831,
0.01640862040221691,
0.016249023377895355,
-0.01848573051393032,
0.0011858115904033184,
-0.01968447118997574,
4.367462567771836e-33,
-0.003966659773141146,
-0.04437390714883804,
0.056106921285390854,
0.04075118899345398,
-0.06616934388875961,
0.11175000667572021,
0.06129138544201851,
-0.05509846284985542,
-0.03525282070040703,
-0.040051303803920746,
-0.041510146111249924,
0.006628404837101698,
-0.030275888741016388,
0.08161918818950653,
-0.03369814157485962,
-0.05144786089658737,
-0.014754971489310265,
0.03906591609120369,
-0.023781217634677887,
-0.0231261495500803,
0.07410559058189392,
0.05780954658985138,
0.010167575441300869,
-0.06846795231103897,
0.07260775566101074,
0.01261255145072937,
-0.06491976976394653,
0.07828118652105331,
0.06908264011144638,
-0.024846157059073448,
-0.09900972247123718,
-0.033147335052490234,
0.040450625121593475,
0.003086411627009511,
0.00025067757815122604,
-0.03377690538764,
0.010918831452727318,
-0.030220581218600273,
0.028274668380618095,
0.08050671219825745,
-0.069379061460495,
-0.042036086320877075,
-0.020705359056591988,
-0.03198951482772827,
-0.0285964235663414,
-0.02295880764722824,
-0.04351884499192238,
0.005727179814130068,
-0.10084076970815659,
0.0228439774364233,
-0.02170959860086441,
0.02204890549182892,
0.034589983522892,
0.0053079077042639256,
0.02067442238330841,
-0.008919957093894482,
-0.07098465412855148,
0.01001704577356577,
-0.0019919737242162228,
-0.07224127650260925,
-0.006629960145801306,
0.01960086263716221,
0.04429018497467041,
0.01699056848883629,
0.016076425090432167,
0.014775188639760017,
0.038132693618535995,
-0.008141408674418926,
-0.04848036170005798,
0.0933137983083725,
0.06790489703416824,
0.04208013787865639,
-0.03689371049404144,
-0.069913849234581,
-0.0005727460375055671,
-0.04590723291039467,
-0.04293379187583923,
0.07166501879692078,
0.009516021236777306,
0.08145640045404434,
-0.04660552740097046,
-0.004374152515083551,
-0.11530689895153046,
0.07672102749347687,
0.11204878240823746,
-0.06575462222099304,
-0.022547170519828796,
-0.04035329818725586,
0.019741665571928024,
0.044396016746759415,
0.03374237194657326,
0.0005843579419888556,
0.02550562657415867,
0.08054133504629135,
0.027658794075250626,
-3.3761468758882924e-33,
-0.01969938538968563,
-0.04576781392097473,
0.07400966435670853,
-0.027019254863262177,
-0.01652098260819912,
-0.006950981914997101,
0.0689152330160141,
-0.007542576175183058,
0.012113277800381184,
-0.0467393696308136,
0.020683184266090393,
-0.055047113448381424,
-0.08236473053693771,
0.018843967467546463,
-0.03828220069408417,
-0.015208055265247822,
-0.01865229196846485,
0.03026522323489189,
-0.07643412798643112,
0.0003953467239625752,
-0.006867050658911467,
-0.006250254809856415,
-0.0023386147804558277,
0.04572054371237755,
0.0069458200596272945,
-0.017908964306116104,
-0.023444889113307,
0.10873070359230042,
-0.030970856547355652,
-0.004901539999991655,
-0.05359186977148056,
0.06350862234830856,
-0.04049718752503395,
0.003824093844741583,
-0.030724626034498215,
-0.018595675006508827,
0.011824600398540497,
0.028736742213368416,
0.09507308155298233,
-0.031030308455228806,
-0.03459145501255989,
0.09348589926958084,
-0.05303589627146721,
0.04358718544244766,
0.04179944097995758,
0.09477313607931137,
0.10039425641298294,
0.06721754372119904,
0.09903590381145477,
0.05931798741221428,
-0.0880315750837326,
-0.07110869139432907,
0.011534987948834896,
-0.01962577924132347,
-0.03710506483912468,
-0.08522500842809677,
0.055571895092725754,
0.03490765765309334,
0.0643252283334732,
-0.0504385307431221,
0.021985698491334915,
-0.07738899439573288,
-0.029436573386192322,
-0.07124297320842743,
0.024994898587465286,
0.10961845517158508,
0.09797322005033493,
0.015768669545650482,
-0.026392195373773575,
-0.05423402041196823,
0.05755222588777542,
-0.04316264018416405,
-0.051243484020233154,
0.06813885271549225,
-0.011171030811965466,
-0.012662353925406933,
0.016826651990413666,
-0.07686348259449005,
0.06864312291145325,
0.013317235745489597,
0.035982124507427216,
-0.03671741485595703,
0.006389062386006117,
-0.0003835622046608478,
0.10408298671245575,
0.049880895763635635,
0.031586043536663055,
0.0026251061353832483,
-0.03356856852769852,
0.09319252520799637,
-0.08947679400444031,
-0.00512290233746171,
0.09878934919834137,
0.0900040939450264,
-0.07107050716876984,
-3.9590634770547695e-8,
-0.031493887305259705,
-0.0983971431851387,
-0.006947245914489031,
-0.14154629409313202,
0.02861323207616806,
0.013790152035653591,
-0.07826630026102066,
-0.09130823612213135,
0.07537175714969635,
-0.0950598195195198,
0.0014477052027359605,
0.008161705918610096,
-0.002693215385079384,
0.012526747770607471,
0.12154626101255417,
0.007846464402973652,
-0.05403786897659302,
0.062212780117988586,
0.008471409790217876,
-0.04896831884980202,
-0.028818150982260704,
-0.01860583759844303,
-0.05792633816599846,
0.08483194559812546,
-0.04763354733586311,
0.04066365584731102,
0.06798053532838821,
0.08966685086488724,
0.038701221346855164,
-0.06687652319669724,
0.06123114004731178,
-0.010617687366902828,
0.028567567467689514,
0.05455686151981354,
-0.034316591918468475,
0.028044620528817177,
0.048198215663433075,
-0.0035275041591376066,
0.02786988578736782,
0.012534914538264275,
-0.025196745991706848,
-0.04366723820567131,
0.0614241324365139,
-0.04787391424179077,
-0.08605709671974182,
0.0006520246970467269,
-0.05338048189878464,
0.04924199730157852,
0.0007133775507099926,
-0.010571089573204517,
0.0030038421973586082,
-0.049512989819049835,
0.030042044818401337,
-0.02898181602358818,
-0.012974736280739307,
-0.030141469091176987,
0.016909483820199966,
-0.02285338193178177,
0.051969416439533234,
0.013028545305132866,
-0.01707150787115097,
-0.04039803892374039,
0.10537208616733551,
-0.04066368192434311
] |
PMID:19967559 | We showed that toremifene alone significantly downregulated BCRP mRNA and protein levels in estrogen receptor α (ERα)-positive MCF-7 cells in a dose-dependent manner, and the inhibitory effect was partially reversed by estrone (E(1)). | [
-0.04270601272583008,
-0.09527666866779327,
-0.024640100076794624,
0.026292426511645317,
0.01336269173771143,
0.05842280387878418,
0.016489306464791298,
0.1253388524055481,
0.01904527097940445,
0.05947547405958176,
-0.020538168027997017,
-0.040791917592287064,
-0.01363806426525116,
0.0357288159430027,
0.0892377495765686,
0.08536142855882645,
-0.022343045100569725,
0.06078909710049629,
0.02293230965733528,
0.031062917783856392,
-0.04217686876654625,
0.013636711984872818,
-0.03481598570942879,
0.1047842800617218,
-0.035546544939279556,
-0.025778086856007576,
0.07606887072324753,
0.10547535866498947,
-0.10484689474105835,
-0.055484358221292496,
-0.0366029366850853,
0.004143065772950649,
0.044967472553253174,
0.06766843050718307,
0.0295274555683136,
0.024538278579711914,
-0.10415041446685791,
-0.07071879506111145,
-0.01475012581795454,
0.021218329668045044,
-0.004777594935148954,
-0.04953986406326294,
-0.019562771543860435,
0.000059182202676311135,
0.06736183911561966,
-0.018439805135130882,
0.0013936596224084496,
0.07390444725751877,
0.06851634383201599,
0.03600066155195236,
0.04688969627022743,
0.00486745685338974,
-0.05951860174536705,
0.05765489116311073,
0.01257004588842392,
-0.0976739153265953,
-0.059495311230421066,
0.023436948657035828,
0.027287689968943596,
0.055510349571704865,
-0.01954045332968235,
-0.020195772871375084,
-0.0023407479748129845,
0.015206247568130493,
0.01836954616010189,
0.0393502414226532,
-0.04364211484789848,
0.01271447166800499,
0.03277207165956497,
0.005348503589630127,
0.055468589067459106,
-0.03699387609958649,
-0.04253917932510376,
0.023660046979784966,
0.04288165271282196,
0.010131402872502804,
0.01950659044086933,
-0.010336453095078468,
0.008171427994966507,
-0.0776013433933258,
0.020457563921809196,
-0.04478556662797928,
0.09317600727081299,
0.08011160045862198,
0.015017056837677956,
-0.04634880647063255,
0.011997634544968605,
-0.02213902585208416,
-0.024251747876405716,
0.11062487214803696,
0.10988645255565643,
0.026039205491542816,
0.06782415509223938,
0.058924030512571335,
0.004719695542007685,
0.020995628088712692,
-0.11275419592857361,
0.02548658475279808,
-0.10552642494440079,
0.03304523229598999,
-0.10052049905061722,
0.0722389817237854,
-0.16025830805301666,
-0.013284769840538502,
-0.026439376175403595,
-0.026923054829239845,
0.11454381048679352,
-0.013993755914270878,
-0.04162878915667534,
0.03216993063688278,
0.026153847575187683,
-0.05531296879053116,
0.00267206784337759,
0.033789437264204025,
-0.020101487636566162,
-0.03386557847261429,
0.048006244003772736,
0.011737484484910965,
0.023499198257923126,
-0.09415477514266968,
-0.001088657882064581,
-0.018712401390075684,
0.01804402470588684,
0.010312377475202084,
-0.04727821424603462,
0.05069674551486969,
0.01024036668241024,
1.0144345433573487e-33,
0.04537694901227951,
-0.00046782800927758217,
0.06231158226728439,
0.00594283128157258,
-0.08607833087444305,
0.08244434744119644,
0.0026382559444755316,
-0.05870715156197548,
0.01622127741575241,
-0.1261707842350006,
-0.09699830412864685,
-0.022300198674201965,
-0.022991878911852837,
0.011908475309610367,
0.037706248462200165,
-0.10970776528120041,
0.03440140560269356,
0.043364908546209335,
0.015691498294472694,
-0.023179776966571808,
0.05482715368270874,
0.04090459644794464,
-0.022467929869890213,
-0.135265052318573,
-0.025096524506807327,
0.042094480246305466,
-0.024552656337618828,
0.06399434059858322,
-0.014567585662007332,
0.007280193269252777,
-0.11388345062732697,
-0.05388379096984863,
0.0015912912786006927,
0.06029214709997177,
0.05026814714074135,
-0.10037560760974884,
-0.004569428041577339,
-0.004724497441202402,
-0.013438296504318714,
0.05094991251826286,
-0.040969762951135635,
-0.003546015126630664,
0.0028563649393618107,
-0.06441204249858856,
-0.024866260588169098,
-0.1136808842420578,
-0.036505796015262604,
-0.008251599036157131,
-0.007534474600106478,
0.022327970713377,
-0.0008664275519549847,
-0.01872759312391281,
0.04660452529788017,
0.040550436824560165,
-0.03597989305853844,
0.004379237536340952,
-0.055954206734895706,
-0.07177291065454483,
0.04038476571440697,
0.0000997562165139243,
0.012712097726762295,
0.04845021292567253,
0.08170714229345322,
-0.04047873616218567,
0.013782781548798084,
0.032617177814245224,
-0.031394895166158676,
-0.020606476813554764,
-0.07362708449363708,
-0.002364610554650426,
-0.02692492865025997,
-0.019962139427661896,
0.09662039577960968,
-0.03082265518605709,
-0.041174910962581635,
0.052491363137960434,
-0.02798999473452568,
0.12472447007894516,
0.034673403948545456,
-0.04632185027003288,
-0.05740844085812569,
-0.13925951719284058,
-0.07121950387954712,
0.11568302661180496,
0.0695498138666153,
0.016899943351745605,
-0.0030809177551418543,
-0.09026477485895157,
-0.01675935462117195,
-0.01114062312990427,
0.047612350434064865,
-0.05422809720039368,
-0.05987487733364105,
0.05448995903134346,
0.0013977674534544349,
-1.4172368762853026e-33,
-0.007629322353750467,
-0.028789980337023735,
0.016309380531311035,
-0.039390917867422104,
-0.08075674623250961,
-0.006784289143979549,
0.028414394706487656,
-0.04362979903817177,
0.04332839697599411,
0.015708541497588158,
0.0744490772485733,
-0.007789631839841604,
-0.045330364257097244,
-0.04501485452055931,
-0.026226507499814034,
-0.04460529983043671,
0.04334300011396408,
0.037791598588228226,
-0.06527930498123169,
-0.0950731411576271,
-0.05308297649025917,
-0.007723053451627493,
-0.011596852913498878,
0.03145016357302666,
0.03793860599398613,
0.03476112335920334,
0.054733626544475555,
0.03481634706258774,
0.07459989935159683,
0.021460112184286118,
-0.021051209419965744,
0.04766619950532913,
-0.0677267462015152,
-0.04025960713624954,
0.06437454372644424,
0.05520280823111534,
0.03688230365514755,
0.01046798937022686,
0.027829544618725777,
-0.07359784841537476,
-0.023825665935873985,
0.05820867419242859,
-0.05637045577168465,
-0.01014851313084364,
0.09298521280288696,
0.08752484619617462,
0.055656157433986664,
0.07047754526138306,
0.05020170286297798,
0.04909922555088997,
-0.008252831175923347,
-0.044869210571050644,
0.04662745073437691,
-0.020596003159880638,
-0.0788050964474678,
-0.10669500380754471,
0.0460997000336647,
-0.017211051657795906,
-0.02065218798816204,
0.03245162591338158,
-0.015298516489565372,
-0.02811608649790287,
0.007151840254664421,
-0.0534353107213974,
0.022436024621129036,
0.012755525298416615,
-0.04620346426963806,
-0.05000367388129234,
0.014673952013254166,
-0.01737845130264759,
0.039082612842321396,
-0.060548458248376846,
0.017185809090733528,
0.02463311329483986,
-0.03633835166692734,
-0.06576832383871078,
-0.026213599368929863,
-0.0495186485350132,
0.05938884988427162,
0.020583216100931168,
-0.011499130167067051,
-0.043479304760694504,
-0.04436081647872925,
-0.02833738923072815,
-0.004190734587609768,
-0.00965938437730074,
-0.017065204679965973,
0.0026907618157565594,
0.026444684714078903,
0.029062476009130478,
-0.03286989405751228,
-0.0449492447078228,
0.015774289146065712,
0.07838979363441467,
-0.07941218465566635,
-3.1253883037152264e-8,
0.030169067904353142,
-0.011026566848158836,
0.041408248245716095,
-0.07126980274915695,
0.0588814914226532,
-0.040540363639593124,
-0.03985859826207161,
-0.007172391749918461,
0.03943684697151184,
-0.04759475216269493,
0.05094759538769722,
0.02062164805829525,
-0.014013905078172684,
0.01007494330406189,
0.013162716291844845,
0.022673431783914566,
0.05513102561235428,
0.0486256442964077,
0.019987398758530617,
-0.017606474459171295,
0.026647178456187248,
-0.12049344182014465,
-0.014852035790681839,
-0.028981048613786697,
0.022856881842017174,
-0.033889975398778915,
0.03863734006881714,
0.03666470944881439,
0.010270286351442337,
-0.03245677426457405,
0.12199447304010391,
-0.04475788772106171,
0.05135437846183777,
0.04986124485731125,
-0.03404289111495018,
0.09201207011938095,
0.023619461804628372,
0.00401562824845314,
0.012421557679772377,
0.04711209610104561,
-0.05225281044840813,
-0.04321825131773949,
0.011396903544664383,
0.02048422023653984,
-0.005220773629844189,
0.0225064679980278,
0.09154795855283737,
0.059948306530714035,
-0.01788461022078991,
-0.044599391520023346,
0.020733891054987907,
0.04923507571220398,
0.025128435343503952,
-0.04391723498702049,
-0.011423511430621147,
0.019093574956059456,
0.034627221524715424,
-0.02358550764620304,
0.15997539460659027,
-0.024573229253292084,
-0.02539021521806717,
-0.07064361125230789,
0.05681191384792328,
-0.0014142628060653806
] |
PMID:19967559 | Furthermore, gel shift assays demonstrated that specific binding of ERα to the ERE in the BCRP promoter is essential for transcriptional inhibition of BCRP by toremifene. | [
-0.12632066011428833,
-0.04086340218782425,
-0.059348151087760925,
-0.025718912482261658,
0.010145976208150387,
0.04621119797229767,
0.0188697949051857,
0.12752051651477814,
0.012061573565006256,
0.0027292021550238132,
-0.04046403989195824,
-0.0736515149474144,
-0.01038664486259222,
0.03744963929057121,
0.08025503158569336,
0.06946071982383728,
-0.05924663320183754,
0.07537517696619034,
-0.03338557109236717,
-0.06012609228491783,
-0.00855354592204094,
0.04777301102876663,
0.003425807459279895,
0.07285063713788986,
-0.013087175786495209,
-0.027139777317643166,
0.08760301023721695,
0.029900413006544113,
-0.053499191999435425,
-0.09486560523509979,
0.0029103560373187065,
-0.027601860463619232,
0.05998905748128891,
0.011600038036704063,
0.037549134343862534,
0.00939992442727089,
-0.0641963854432106,
-0.05136493965983391,
0.01365586742758751,
-0.011603264138102531,
0.07444757223129272,
-0.02315668947994709,
-0.029560085386037827,
-0.006981377024203539,
0.03996550664305687,
0.010372123681008816,
0.021499279886484146,
0.083647720515728,
0.024466536939144135,
0.06285934895277023,
0.014785140752792358,
0.026288846507668495,
-0.033076927065849304,
0.0429086834192276,
-0.03225228935480118,
-0.016407759860157967,
0.003874972928315401,
0.03720279410481453,
0.07075802981853485,
0.008196414448320866,
0.0042317272163927555,
-0.04978824034333229,
0.03816099464893341,
0.00048259078175760806,
-0.03820658475160599,
0.02631399966776371,
0.0014053081395104527,
-0.011548890732228756,
0.012099080719053745,
-0.05073191225528717,
-0.054100338369607925,
-0.06547248363494873,
-0.044952478259801865,
0.06317057460546494,
0.05773131176829338,
0.032856233417987823,
0.04457114264369011,
0.06083786115050316,
-0.034182026982307434,
-0.07376715540885925,
0.05702904239296913,
-0.02724699303507805,
0.10512439906597137,
0.12333010882139206,
0.013478606939315796,
0.04773007333278656,
0.005994547624140978,
-0.06493493914604187,
-0.007892492227256298,
0.09632503986358643,
0.18495316803455353,
-0.06747070699930191,
0.04384000971913338,
0.0341557040810585,
-0.001655430649407208,
0.01946955733001232,
-0.06957095116376877,
-0.029317736625671387,
-0.03451097384095192,
0.0033373329788446426,
-0.09297606348991394,
0.009796025231480598,
-0.09842164069414139,
-0.026035260409116745,
-0.013089744374155998,
-0.07062768191099167,
0.025807585567235947,
-0.001490191207267344,
0.051501840353012085,
0.020301735028624535,
0.05700830742716789,
-0.0470956452190876,
0.06934425979852676,
0.030141491442918777,
-0.0316503569483757,
-0.0317906029522419,
0.005308298859745264,
0.024049656465649605,
-0.012414415366947651,
-0.05978494510054588,
0.030762353911995888,
-0.006757375318557024,
-0.03286585584282875,
0.01441865786910057,
-0.07682570815086365,
-0.0041324975900352,
-0.027532964944839478,
1.606700759863435e-33,
0.04840189963579178,
0.04635535925626755,
-0.04171847924590111,
0.013096400536596775,
-0.1206122562289238,
0.05359313637018204,
-0.06864561140537262,
-0.01374909933656454,
-0.005392151884734631,
-0.06685838103294373,
-0.09494314342737198,
-0.06237911060452461,
0.03723602369427681,
0.022630376741290092,
-0.04373299330472946,
-0.016556736081838608,
-0.002702549798414111,
0.016253752633929253,
0.00473250774666667,
-0.052791282534599304,
0.05231131613254547,
0.021964844316244125,
-0.009895768016576767,
-0.13703571259975433,
-0.05149020254611969,
0.0346895270049572,
-0.03167632967233658,
-0.012818653136491776,
0.08263461291790009,
-0.02191539667546749,
-0.05263310298323631,
-0.06709190458059311,
-0.00846029818058014,
0.04896942153573036,
0.08325585722923279,
-0.02766820602118969,
0.005977075081318617,
-0.061686381697654724,
0.0049578957259655,
0.010413896292448044,
-0.047402042895555496,
0.055308979004621506,
-0.04645038768649101,
-0.03923799842596054,
0.046775758266448975,
-0.12547534704208374,
-0.02201671339571476,
0.003568637417629361,
0.02097928896546364,
0.006650566589087248,
0.0011395597830414772,
0.008177518844604492,
0.12730112671852112,
0.018437765538692474,
0.0011882346589118242,
-0.005666650366038084,
-0.04698443412780762,
-0.057578325271606445,
0.04700634628534317,
-0.05375783517956734,
0.02302977442741394,
0.054077617824077606,
0.042176105082035065,
-0.006247405894100666,
-0.006142943166196346,
0.02491467259824276,
-0.028605947270989418,
0.0010813004337251186,
-0.071138896048069,
-0.001371766091324389,
0.020485106855630875,
-0.017850704491138458,
0.11395208537578583,
-0.04805470630526543,
-0.11444336920976639,
-0.045868881046772,
-0.06270245462656021,
0.12067686021327972,
0.011443846859037876,
0.008022468537092209,
-0.030041193589568138,
-0.1013571098446846,
-0.05698307976126671,
0.08309506624937057,
0.0733942836523056,
-0.03747520223259926,
0.029758209362626076,
-0.046229004859924316,
-0.06889235973358154,
-0.0034581704530864954,
0.07997752726078033,
-0.055679403245449066,
-0.09184608608484268,
0.10712989419698715,
0.03909963741898537,
-1.8110395142607656e-33,
0.03790723904967308,
-0.04933418333530426,
0.06277478486299515,
-0.04711887240409851,
-0.03389442339539528,
-0.046060219407081604,
0.07399402558803558,
-0.01995995081961155,
0.01676926575601101,
0.021521609276533127,
0.10685230791568756,
0.014828422106802464,
-0.065544493496418,
-0.03536554053425789,
-0.03866857662796974,
-0.05150992423295975,
0.04193131998181343,
0.05729878693819046,
-0.057938359677791595,
-0.05972298979759216,
-0.037800174206495285,
-0.012296817265450954,
-0.038658976554870605,
0.06556284427642822,
0.008717045187950134,
0.013364224694669247,
0.05314067751169205,
0.062003664672374725,
-0.013390690088272095,
0.010071512311697006,
-0.010129987262189388,
0.04442717507481575,
-0.049136288464069366,
-0.06268371641635895,
0.02349691279232502,
0.08201165497303009,
0.020759478211402893,
0.04398300498723984,
-0.022695831954479218,
-0.12601584196090698,
0.0003248397260904312,
0.02583405002951622,
-0.04443308711051941,
0.020510708913207054,
0.1374615877866745,
0.13078178465366364,
0.032931141555309296,
0.08380298316478729,
-0.004521813243627548,
0.0477231964468956,
0.06028171628713608,
-0.004625784698873758,
0.04394857585430145,
-0.025370663031935692,
-0.0415961779654026,
-0.07201312482357025,
0.01555789913982153,
-0.012868871912360191,
-0.09314905852079391,
0.007483238819986582,
-0.04060076177120209,
0.009308170527219772,
0.08387742191553116,
-0.0053186360746622086,
0.012157789431512356,
0.05611052364110947,
-0.029977761209011078,
-0.004754462279379368,
0.049575649201869965,
-0.05163488909602165,
0.052603598684072495,
-0.029540421441197395,
0.04121094569563866,
-0.0018049172358587384,
-0.05188945680856705,
-0.025332743301987648,
-0.024437908083200455,
-0.07457801699638367,
0.05648494511842728,
-0.026269489899277687,
-0.032022666186094284,
-0.04666655883193016,
-0.010903535410761833,
0.0069743008352816105,
-0.0014815726317465305,
0.018799254670739174,
-0.03244315832853317,
-0.008864026516675949,
-0.015355505980551243,
-0.011771433986723423,
-0.01977011375129223,
-0.05625070258975029,
0.03801485151052475,
0.0685952752828598,
0.01010461337864399,
-2.6097167094008e-8,
0.05352130904793739,
-0.0034014086704701185,
0.022636989131569862,
-0.07869791239500046,
0.02949516847729683,
-0.030755676329135895,
-0.019419189542531967,
0.008218119852244854,
-0.00859876535832882,
-0.026014886796474457,
-0.022363854572176933,
-0.006359983701258898,
-0.027918720617890358,
0.036740273237228394,
0.09674288332462311,
0.028268683701753616,
0.02444406785070896,
0.003964989446103573,
-0.018346339464187622,
-0.01663384400308132,
0.03395766764879227,
-0.04730778932571411,
0.010924126021564007,
-0.0009452039375901222,
0.02172474004328251,
-0.08993224799633026,
0.05207982286810875,
-0.018042901530861855,
0.04839157685637474,
-0.06458655744791031,
0.11740797013044357,
-0.06359940022230148,
0.0342879593372345,
0.03734597936272621,
-0.007833674550056458,
0.06629641354084015,
-0.022926410660147667,
-0.022616153582930565,
0.02334376610815525,
0.0769876018166542,
-0.008824143558740616,
-0.05501348897814751,
0.01128927432000637,
-0.017476659268140793,
-0.024132635444402695,
0.03040793165564537,
0.05852223560214043,
0.05603723227977753,
-0.03583398833870888,
-0.08991244435310364,
0.027591075748205185,
-0.03216619789600372,
0.029551146551966667,
-0.052909258753061295,
-0.07934030890464783,
-0.0104209054261446,
0.018072722479701042,
-0.01109149307012558,
0.1567305028438568,
0.019931232556700706,
-0.011020406149327755,
-0.03490946441888809,
0.049567848443984985,
-0.02586369775235653
] |
PMID:19967559 | Interestingly, toremifene alone increased the cellular accumulation of mitoxantrone in BCRP-transfected cells, suggesting that TOR indeed inhibits BCRP-mediated drug efflux and overcome drug resistance. | [
-0.06042579934000969,
-0.0021995739080011845,
-0.04440997913479805,
-0.030114488676190376,
-0.00955197773873806,
0.041837871074676514,
-0.07125164568424225,
0.17890740931034088,
-0.02029062807559967,
-0.0054642874747514725,
0.011714152991771698,
-0.01845586486160755,
0.12799932062625885,
0.04214873164892197,
0.015150492079555988,
0.07600268721580505,
-0.0328703299164772,
0.08542225509881973,
0.0011883164988830686,
0.009240389801561832,
-0.0638352558016777,
0.017339235171675682,
0.042963702231645584,
0.07812457531690598,
-0.03640712797641754,
0.03756403550505638,
0.026985909789800644,
0.08095499873161316,
-0.04306790232658386,
-0.053620412945747375,
0.01016256120055914,
0.030039604753255844,
-0.07769889384508133,
0.04975632205605507,
0.02998942695558071,
0.0006219380884431303,
-0.119998037815094,
0.031547099351882935,
-0.006211246829479933,
-0.011377180926501751,
-0.0032889407593756914,
-0.027520639821887016,
-0.054942697286605835,
0.027637651190161705,
0.058669138699769974,
-0.07515933364629745,
-0.002091344678774476,
0.04118463397026062,
0.031711362302303314,
0.04887969791889191,
-0.00665387324988842,
0.07138333469629288,
-0.02795802243053913,
0.09945324063301086,
-0.011420675553381443,
-0.05132494494318962,
-0.05286983400583267,
0.08939962089061737,
0.039671555161476135,
0.012060741893947124,
-0.033094923943281174,
0.014906700700521469,
0.055702850222587585,
0.03249173238873482,
-0.017366420477628708,
0.04171321541070938,
-0.043215878307819366,
-0.012210151180624962,
0.049874015152454376,
-0.0037014081608504057,
0.028453242033720016,
-0.06139137223362923,
0.031561993062496185,
0.024058053269982338,
0.009790826588869095,
-0.03585752099752426,
-0.021261734887957573,
-0.00034676483483053744,
-0.06699302792549133,
-0.0013571029994636774,
0.024153169244527817,
-0.024588895961642265,
0.084389328956604,
0.12538036704063416,
0.028706973418593407,
-0.007784821093082428,
0.05171007663011551,
-0.035014957189559937,
-0.024108566343784332,
0.05761832371354103,
0.13756443560123444,
0.04797643795609474,
-0.02085905894637108,
0.026953749358654022,
-0.03378428891301155,
-0.036233656108379364,
-0.05638592317700386,
0.035885971039533615,
-0.11712804436683655,
-0.003776919562369585,
-0.03050221875309944,
-0.009230773895978928,
-0.16720174252986908,
-0.03910510241985321,
0.040441643446683884,
-0.038796864449977875,
0.12366852909326553,
-0.03630907088518143,
-0.011601690202951431,
0.031553007662296295,
0.059939634054899216,
-0.029651107266545296,
0.03542313352227211,
0.026842132210731506,
-0.04208323732018471,
0.015758007764816284,
0.02930515632033348,
0.015375363640487194,
0.007095933426171541,
0.012342558242380619,
0.0655810758471489,
0.006679584737867117,
-0.046658892184495926,
-0.05338827893137932,
-0.05280201882123947,
0.020424911752343178,
0.02036857232451439,
2.828429691226463e-33,
0.004322781227529049,
0.023918582126498222,
0.0276109017431736,
0.04329229146242142,
-0.04616573452949524,
0.005207355134189129,
-0.021392779424786568,
-0.039379168301820755,
0.010438641533255577,
-0.0857900008559227,
-0.19458052515983582,
-0.011022195219993591,
-0.017472686246037483,
0.06447913497686386,
-0.07232077419757843,
-0.060880374163389206,
-0.05982700362801552,
-0.0053338645957410336,
0.05570961907505989,
-0.05248130112886429,
0.046241309493780136,
0.0007207698072306812,
-0.0029494035989046097,
-0.12560971081256866,
-0.09593907743692398,
0.05772499367594719,
-0.0010095889447256923,
0.046032171696424484,
0.0347178690135479,
-0.000586618494708091,
-0.03706928715109825,
-0.03191074728965759,
-0.08104245364665985,
0.03548813983798027,
0.02125619910657406,
-0.0042115990072488785,
-0.011592467315495014,
-0.07136180996894836,
-0.04614103212952614,
0.054375506937503815,
-0.1009935587644577,
0.037128996104002,
-0.05019371584057808,
-0.07361559569835663,
0.024345040321350098,
-0.09460242837667465,
-0.07464485615491867,
-0.000660677847918123,
-0.038866933435201645,
0.012381736189126968,
0.09926722198724747,
-0.02729889564216137,
0.08535286784172058,
0.012539636343717575,
0.011982502415776253,
-0.00899652298539877,
-0.05627225339412689,
-0.05716262012720108,
0.04740139842033386,
0.0212386641651392,
0.016140053048729897,
0.049370914697647095,
0.008886936120688915,
-0.025862444192171097,
0.026663435623049736,
0.02497129887342453,
-0.005190318915992975,
0.0054865810088813305,
-0.0855683982372284,
-0.040079664438962936,
-0.0659107193350792,
-0.030003992840647697,
0.04217845946550369,
0.03442037105560303,
-0.008635535836219788,
-0.0010096951154991984,
-0.022195998579263687,
0.0618906244635582,
0.04269293695688248,
-0.05209767818450928,
-0.04169653728604317,
-0.15514330565929413,
0.01593005657196045,
0.05391429364681244,
0.04064765200018883,
0.009047050029039383,
-0.018659109249711037,
-0.05744997411966324,
-0.019355541095137596,
-0.01769331470131874,
0.08743230998516083,
-0.0616135336458683,
-0.058780230581760406,
0.07059827446937561,
-0.035110410302877426,
-3.1337500225151516e-33,
-0.033999908715486526,
-0.02783706784248352,
0.04030987247824669,
-0.07772910594940186,
-0.0385301373898983,
0.036363180726766586,
-0.038226574659347534,
-0.06141326576471329,
0.07025151699781418,
0.02771398238837719,
0.06300009042024612,
0.03353387489914894,
-0.020270496606826782,
-0.013560242019593716,
-0.004436223767697811,
-0.03170527145266533,
0.05695794150233269,
-0.02871002070605755,
-0.04868065193295479,
-0.01943374238908291,
-0.03232252597808838,
0.013400936499238014,
-0.09577144682407379,
0.06574126332998276,
-0.014270276762545109,
0.030711974948644638,
0.08055057376623154,
0.020556505769491196,
0.09484690427780151,
0.008942839689552784,
0.058229632675647736,
0.013951078988611698,
-0.07700464129447937,
-0.016691092401742935,
0.06477157771587372,
0.12156663835048676,
0.007814283482730389,
-0.02024691179394722,
0.01748061552643776,
-0.09052246809005737,
-0.011264647357165813,
-0.03278764337301254,
-0.03676662594079971,
0.025137625634670258,
0.08767709881067276,
0.04092340171337128,
-0.02963307872414589,
0.002136698691174388,
0.012652738019824028,
0.020089875906705856,
0.04047076404094696,
0.04942133277654648,
0.041557494550943375,
-0.020847102627158165,
0.03207729384303093,
-0.03401420637965202,
-0.036384522914886475,
-0.09231110662221909,
-0.020482385531067848,
-0.03000098280608654,
-0.00829689484089613,
-0.005096389912068844,
-0.00609574792906642,
-0.06378450244665146,
0.031835366040468216,
0.06835349649190903,
-0.06993589550256729,
-0.019597947597503662,
0.013015354983508587,
-0.011450573801994324,
0.06303904205560684,
-0.011911400593817234,
0.015539059415459633,
-0.07035145908594131,
-0.06569292396306992,
0.02176753059029579,
0.03062034212052822,
-0.046492237597703934,
0.03211408853530884,
-0.013359815813601017,
0.03399045392870903,
0.03989848122000694,
0.024291088804602623,
-0.09705766290426254,
-0.04362838342785835,
-0.004353038966655731,
-0.02196013182401657,
-0.0155852772295475,
-0.0032435611356049776,
-0.030367536470294,
0.03415898606181145,
-0.046153172850608826,
-0.018319694325327873,
0.05872734636068344,
0.022799313068389893,
-2.8222004289091274e-8,
0.0887111946940422,
0.038978829979896545,
0.037864070385694504,
-0.017861418426036835,
-0.06181732192635536,
-0.037600383162498474,
0.06860504299402237,
0.026821307837963104,
-0.0013812214601784945,
-0.0025420114398002625,
0.03062320686876774,
0.060523878782987595,
0.0450228750705719,
0.035606540739536285,
0.02722063846886158,
0.10734637826681137,
-0.010674909688532352,
0.027899138629436493,
0.004088747780770063,
0.013009767979383469,
-0.030904363840818405,
-0.04935668781399727,
0.011072644963860512,
0.02452828548848629,
0.03477400168776512,
-0.08154372870922089,
0.061439938843250275,
-0.04068576544523239,
0.04072434827685356,
-0.026977214962244034,
0.05484339967370033,
-0.06983162462711334,
0.011105779558420181,
0.04151994362473488,
-0.05079978331923485,
0.07170172035694122,
-0.017358852550387383,
0.007534310687333345,
0.06783541291952133,
0.035461243242025375,
-0.01867944933474064,
-0.08578522503376007,
0.004495702218264341,
-0.003606602782383561,
0.02189435064792633,
0.011473762802779675,
0.06066522374749184,
0.0683298408985138,
-0.06105997413396835,
-0.056364547461271286,
0.03154006600379944,
0.02298244647681713,
0.03005635179579258,
-0.08556196838617325,
-0.03299504891037941,
0.06689578294754028,
0.021800091490149498,
-0.03223104774951935,
0.10282929986715317,
-0.09798330068588257,
-0.08590054512023926,
-0.0265362486243248,
0.0896942988038063,
0.0367182157933712
] |
PMID:19967559 | To the best of our knowledge, this is the first report describing a direct effect of toremifene on BCRP. | [
-0.09694448858499527,
0.0024059333372861147,
-0.01532072015106678,
0.031307026743888855,
-0.02119271084666252,
0.025768514722585678,
-0.03898828104138374,
0.2193620204925537,
-0.058104388415813446,
0.014455894008278847,
-0.0267567690461874,
-0.051002368330955505,
0.055910419672727585,
0.0994601771235466,
-0.025177428498864174,
0.056983582675457,
0.03340074419975281,
0.014936051331460476,
-0.0015067221829667687,
0.02326841652393341,
-0.005178456194698811,
0.07111284881830215,
-0.0074971686117351055,
0.10485073924064636,
-0.04647774621844292,
0.016725772991776466,
-0.005222392734140158,
0.07088229060173035,
-0.05427290126681328,
-0.03164646774530411,
-0.03279786929488182,
0.00861867144703865,
-0.006531920749694109,
0.031046247109770775,
0.06586973369121552,
0.023608658462762833,
-0.06281481683254242,
0.03071986883878708,
-0.00531784538179636,
-0.00899326242506504,
0.03218468651175499,
-0.053546201437711716,
-0.008245487697422504,
-0.03090110793709755,
0.05917680263519287,
-0.014787442050874233,
-0.01564825139939785,
0.09164215624332428,
0.03273013234138489,
0.036771010607481,
-0.02219982072710991,
0.02767149917781353,
0.014758648350834846,
0.0804317444562912,
-0.00032961234683170915,
-0.09390121698379517,
-0.08310818672180176,
0.019343949854373932,
0.010653139092028141,
0.007631121668964624,
-0.08131033927202225,
0.0028688970487564802,
-0.0011069773463532329,
0.03655737265944481,
0.04358956962823868,
0.04364366456866264,
-0.0025413960684090853,
-0.03245843946933746,
0.0726931020617485,
-0.030953196808695793,
0.007105128839612007,
-0.07208742946386337,
0.025777114555239677,
-0.005464795511215925,
0.028970792889595032,
0.027020925655961037,
-0.011981560848653316,
0.03114658035337925,
-0.02722158655524254,
-0.12831474840641022,
0.04353268817067146,
-0.02725289575755596,
0.03998822346329689,
0.10161362588405609,
0.008830501697957516,
0.004934257362037897,
0.05571877583861351,
-0.10216642916202545,
-0.029635313898324966,
0.05967680737376213,
0.14235107600688934,
0.03667781502008438,
0.029363423585891724,
0.040341567248106,
-0.04855331778526306,
0.022542331367731094,
-0.07249102741479874,
-0.04400837421417236,
-0.04763849824666977,
0.024810010567307472,
-0.08429192006587982,
-0.033215973526239395,
-0.1163134053349495,
0.024711648002266884,
-0.03187793865799904,
-0.06997499614953995,
0.058085013180971146,
0.017789334058761597,
0.008991355076432228,
0.026943989098072052,
0.02863612025976181,
0.028837179765105247,
0.0003792167117353529,
-0.008937024511396885,
-0.04757026955485344,
-0.00272475928068161,
0.005759121384471655,
0.01104763150215149,
0.009755805134773254,
-0.054576195776462555,
0.04976997524499893,
-0.05329621955752373,
-0.08289927244186401,
-0.04902597889304161,
-0.01577281951904297,
0.05448581650853157,
0.016355661675333977,
-4.476517586801435e-33,
0.05801833048462868,
0.019927609711885452,
0.043037090450525284,
0.023555688560009003,
-0.0857602134346962,
0.01603509671986103,
-0.06074437126517296,
0.02259877324104309,
0.01623130775988102,
-0.11294298619031906,
-0.09062515199184418,
-0.02819518744945526,
0.058087073266506195,
0.04969002678990364,
-0.08221696317195892,
-0.03840973600745201,
-0.0787518322467804,
0.054442815482616425,
-0.015919087454676628,
-0.019330741837620735,
0.023844370618462563,
0.03559047356247902,
0.0025759267155081034,
-0.10030956566333771,
-0.026278337463736534,
0.03983190655708313,
-0.010257761925458908,
-0.011799398809671402,
-0.008544737473130226,
0.02513899840414524,
-0.06206061691045761,
0.04716413840651512,
-0.06650593131780624,
0.00575731135904789,
0.001508345827460289,
0.015642991289496422,
-0.004786857403814793,
-0.05932595208287239,
-0.0356033593416214,
0.04547598585486412,
-0.07503270357847214,
0.08189652115106583,
-0.019752170890569687,
-0.06552494317293167,
0.04072731360793114,
-0.1162734180688858,
-0.09922970831394196,
0.010313748382031918,
0.030234502628445625,
0.008310423232614994,
0.03185713291168213,
0.06578598916530609,
0.0814816802740097,
0.0028580003418028355,
0.027880968526005745,
0.01030634343624115,
0.0015457110712304711,
-0.10141351819038391,
0.04923134669661522,
0.011955228634178638,
0.07062132656574249,
0.0862777903676033,
0.0017772268038243055,
-0.09541212022304535,
-0.01067973393946886,
-0.0007473785663023591,
-0.024064164608716965,
-0.007865139283239841,
-0.08260183781385422,
-0.10078184306621552,
-0.05411793664097786,
0.022438379004597664,
0.0694354772567749,
-0.029538286849856377,
-0.04150872677564621,
-0.00935230404138565,
-0.01439305767416954,
0.0935591533780098,
0.02989339828491211,
-0.07660101354122162,
-0.018072642385959625,
-0.16161787509918213,
0.0765952616930008,
0.05893704667687416,
0.014756607823073864,
0.03649365156888962,
0.003556017531082034,
-0.07394776493310928,
-0.10684477537870407,
-0.04070058465003967,
0.058540429919958115,
-0.032206397503614426,
-0.024322034791111946,
0.07696442306041718,
-0.018194573000073433,
2.899838585316017e-33,
-0.07018369436264038,
-0.012737497687339783,
0.039651621133089066,
-0.0006381393177434802,
-0.05805586650967598,
-0.039796024560928345,
-0.06277122348546982,
0.03370857983827591,
0.06798537075519562,
0.048084091395139694,
0.10443055629730225,
0.018340718001127243,
-0.016881480813026428,
-0.0327310711145401,
-0.03476974368095398,
0.0320344939827919,
0.04060602933168411,
-0.04890968278050423,
-0.09095683693885803,
0.0015654502203688025,
0.039580266922712326,
0.04664665088057518,
-0.016109401360154152,
0.007285462226718664,
0.009678099304437637,
0.02688763476908207,
0.09971558302640915,
-0.009740830399096012,
0.06096022576093674,
-0.01827068440616131,
0.05782432109117508,
0.03138228878378868,
-0.07109284400939941,
-0.04261999577283859,
0.03507595136761665,
0.09061793237924576,
0.06033666431903839,
-0.05683039873838425,
0.0009630269487388432,
-0.09660477191209793,
0.050670064985752106,
0.0032997909002006054,
-0.018111003562808037,
-0.0023113838396966457,
0.06335891783237457,
0.043075062334537506,
0.01380749512463808,
0.011077720671892166,
0.02698800526559353,
0.05612668767571449,
0.05150304362177849,
0.0424935482442379,
0.03495534136891365,
-0.005014878697693348,
-0.015247209928929806,
-0.09552094340324402,
0.013271177187561989,
-0.06499499827623367,
-0.08716511726379395,
-0.02059318870306015,
0.00036967499181628227,
0.05489659681916237,
-0.06744566559791565,
-0.07129725068807602,
0.04785846173763275,
0.012830435298383236,
-0.07208769023418427,
-0.02087477780878544,
0.07667940109968185,
-0.06776145100593567,
0.04573255404829979,
-0.06108303368091583,
-0.013935797847807407,
-0.09294870495796204,
-0.02848702482879162,
0.01142171397805214,
0.0235885139554739,
-0.07044278830289841,
-0.013915443792939186,
0.06792622059583664,
0.0036892383359372616,
-0.01437130756676197,
0.03538564220070839,
-0.015843817964196205,
0.013952120207250118,
-0.024922166019678116,
-0.01987694948911667,
-0.05757075920701027,
-0.030478082597255707,
0.023236053064465523,
-0.10434088855981827,
-0.049546413123607635,
0.02282571792602539,
0.05937616154551506,
0.04731344059109688,
-2.5129144987090513e-8,
0.09432980418205261,
0.015103490091860294,
0.006184489466249943,
0.04713255539536476,
0.015513102523982525,
-0.020974503830075264,
-0.02632940001785755,
0.020242417231202126,
-0.049455173313617706,
-0.004304374568164349,
-0.0005130223580636084,
0.11104053258895874,
0.020615391433238983,
0.017469290643930435,
0.018038388341665268,
0.008510037325322628,
-0.005381893366575241,
-0.019792702049016953,
-0.04399898275732994,
-0.03279174491763115,
-0.021104037761688232,
-0.04928061366081238,
0.055864572525024414,
-0.03797544911503792,
0.02758108824491501,
-0.036589473485946655,
0.06482448428869247,
-0.029297348111867905,
0.025068974122405052,
-0.009830241091549397,
-0.008998367935419083,
-0.028034891933202744,
0.016477392986416817,
0.001215812866576016,
-0.0022165770642459393,
0.09439554810523987,
-0.012684431858360767,
0.0569097176194191,
0.04618089646100998,
0.04091950133442879,
0.0020586359314620495,
-0.03933946043252945,
0.002373799681663513,
0.07454564422369003,
0.029139552265405655,
0.011397447437047958,
-0.018329009413719177,
0.05384466424584389,
-0.04842859134078026,
-0.08227743953466415,
0.055727601051330566,
0.006599636282771826,
0.04394390061497688,
-0.0018200427293777466,
-0.02241317555308342,
0.07333960384130478,
0.0179997980594635,
-0.08157815039157867,
0.11345040053129196,
-0.03325144201517105,
0.009233479388058186,
-0.008625650778412819,
0.02552410587668419,
0.09101512283086777
] |
PMID:19967559 | Our results thus indicate that toremifene by itself downregulates BCRP expression to reverse BCRP-mediated atypical multidrug resistance via a novel transcriptionally mechanism, which might be involved in TOR-ER complexes binding to the ERE of BCRP promoter to repress transcription of BCRP gene. | [
-0.1536884754896164,
-0.01300005242228508,
-0.028366852551698685,
-0.007274207193404436,
0.005683524068444967,
0.04851018637418747,
-0.016708727926015854,
0.1238287091255188,
0.007826377637684345,
0.0073600769974291325,
-0.0049380287528038025,
-0.10060034692287445,
0.08451661467552185,
0.04510249197483063,
0.043600089848041534,
0.038555122911930084,
-0.08589160442352295,
0.09612546861171722,
-0.017728112637996674,
-0.028377842158079147,
-0.03296506032347679,
0.0978243425488472,
0.02972702868282795,
0.09787890315055847,
-0.054316196590662,
-0.024658169597387314,
0.058953460305929184,
0.0626513734459877,
-0.057000454515218735,
-0.10686046630144119,
0.01611003652215004,
0.0003117415471933782,
-0.034162890166044235,
0.05104871839284897,
0.03528709337115288,
0.014640595763921738,
-0.07100622355937958,
-0.008310784585773945,
0.0576503612101078,
-0.019242895767092705,
0.0813969150185585,
-0.011888827197253704,
0.003118914319202304,
-0.024453235790133476,
0.07217483967542648,
0.01590462028980255,
0.025517506524920464,
0.061737556010484695,
0.05470671132206917,
-0.00038266630144789815,
0.014789498411118984,
0.049307677894830704,
0.012364587746560574,
0.07958055287599564,
0.010727972723543644,
-0.027628807350993156,
-0.04957832023501396,
0.06008651852607727,
0.04271256923675537,
0.007555356714874506,
0.0057172090746462345,
-0.019553551450371742,
0.03491989150643349,
0.012957273982465267,
-0.0013206274015828967,
0.04055903106927872,
0.007866599597036839,
-0.010582013055682182,
0.07067284733057022,
-0.02235240302979946,
-0.045024335384368896,
-0.06857648491859436,
-0.019735518842935562,
0.05426079034805298,
0.08931440860033035,
0.04145566746592522,
-0.041799504309892654,
0.050196465104818344,
-0.07735900580883026,
-0.05130499601364136,
0.026972945779561996,
-0.016654087230563164,
0.09289681911468506,
0.12645269930362701,
0.020546095445752144,
-0.041541945189237595,
0.025647716596722603,
-0.05972081795334816,
-0.027803461998701096,
0.060858022421598434,
0.11474775522947311,
-0.02753416821360588,
0.043211814016103745,
0.05073342099785805,
-0.05896160006523132,
0.015910739079117775,
-0.040952783077955246,
-0.012802500277757645,
-0.0675911083817482,
-0.012375435791909695,
-0.0815315917134285,
-0.047460246831178665,
-0.0927920788526535,
-0.06021904572844505,
0.035670313984155655,
-0.088237464427948,
0.0632697343826294,
-0.047750093042850494,
0.038550976663827896,
0.03401467576622963,
0.09580111503601074,
-0.012615709565579891,
0.06397989392280579,
0.049685921519994736,
-0.06307219713926315,
0.0029766445513814688,
-0.01758575439453125,
0.038150034844875336,
0.011672739870846272,
-0.012602057307958603,
0.019884595647454262,
-0.033687129616737366,
-0.07987494021654129,
-0.041808754205703735,
-0.0786539763212204,
-0.005642564967274666,
-0.011474493891000748,
4.204338482024258e-33,
0.045491646975278854,
0.03784840181469917,
-0.005387498997151852,
0.027267057448625565,
-0.09516794234514236,
0.000697843381203711,
-0.0767662301659584,
-0.020662561058998108,
-0.01675107143819332,
-0.020013876259326935,
-0.13322857022285461,
-0.049033742398023605,
-0.01017728727310896,
0.07817929983139038,
-0.10633314400911331,
-0.0367216058075428,
-0.0516432486474514,
0.015578573569655418,
0.01346994936466217,
-0.09044552594423294,
0.028770655393600464,
0.06975224614143372,
-0.015198398381471634,
-0.1474900096654892,
-0.0007334743277169764,
0.056204572319984436,
0.0020426930859684944,
-0.021633053198456764,
0.0679132342338562,
0.002726375823840499,
-0.026965590193867683,
-0.0020745517686009407,
-0.02077757753431797,
0.0630345344543457,
0.06306662410497665,
-0.036075059324502945,
0.033068060874938965,
-0.053565360605716705,
-0.02460012026131153,
0.072104312479496,
-0.12460481375455856,
0.04470353201031685,
-0.07558104395866394,
-0.06777222454547882,
0.07427525520324707,
-0.08113714307546616,
-0.014089935459196568,
-0.04694283381104469,
-0.011588320136070251,
0.010925651527941227,
0.024817051365971565,
-0.03866918385028839,
0.09691829234361649,
0.02976514957845211,
-0.0005041724652983248,
-0.04611596092581749,
-0.06161070242524147,
-0.055849552154541016,
0.05016576498746872,
0.039637017995119095,
0.021810639649629593,
0.07765987515449524,
-0.03327585756778717,
-0.03848041221499443,
-0.024070121347904205,
0.00596503634005785,
-0.0009865793399512768,
0.007398014888167381,
-0.044319234788417816,
-0.03158240765333176,
-0.009587063454091549,
-0.021809449419379234,
0.059093933552503586,
-0.05928843095898628,
-0.029312897473573685,
-0.014080308377742767,
-0.031228773295879364,
0.09465335309505463,
0.07075919955968857,
0.01150832511484623,
-0.06702512502670288,
-0.12373706698417664,
0.027358368039131165,
0.0522669292986393,
0.06812652200460434,
-0.005946336779743433,
0.04306735843420029,
-0.09438228607177734,
-0.09004782885313034,
-0.06441552191972733,
0.062246836721897125,
-0.0202200748026371,
-0.05982546880841255,
0.04297463968396187,
0.022796783596277237,
-4.893682899493003e-33,
0.004791288170963526,
-0.03271079063415527,
0.07034999877214432,
-0.04811451956629753,
-0.05538543686270714,
-0.018771912902593613,
-0.0077401092275977135,
-0.03953198343515396,
0.03780703619122505,
0.005662177689373493,
0.0957128182053566,
-0.004617449827492237,
-0.015353750437498093,
0.0014851544983685017,
0.028473351150751114,
-0.040002238005399704,
0.009174741804599762,
0.026702575385570526,
-0.06961619853973389,
-0.0415165014564991,
-0.011096645146608353,
-0.03282219171524048,
-0.05153464525938034,
0.05317552387714386,
-0.004717301577329636,
0.00806870125234127,
0.05422362685203552,
0.08543665707111359,
0.059930603951215744,
0.04954678192734718,
0.016668854281306267,
0.02729078382253647,
-0.09111975878477097,
-0.02863937057554722,
0.009504865854978561,
0.10763003677129745,
-0.0025965094100683928,
0.03723884001374245,
-0.04167377948760986,
-0.11780902743339539,
0.027983305975794792,
-0.005692668724805117,
-0.04521792754530907,
-0.0029735395219177008,
0.1100124791264534,
0.0370914563536644,
-0.02976231276988983,
0.03014373406767845,
0.03050152212381363,
0.0313308909535408,
0.06410787254571915,
0.01079941913485527,
0.05690477043390274,
-0.005813680123537779,
-0.0214996300637722,
-0.0764244943857193,
0.01076311245560646,
-0.02009747549891472,
-0.10123913735151291,
-0.03412450850009918,
-0.05732744559645653,
-0.03745419532060623,
0.04485325515270233,
-0.03852244094014168,
0.03145253285765648,
0.04726368561387062,
-0.01748790219426155,
-0.050984740257263184,
0.06427318602800369,
-0.020959753543138504,
0.07207880914211273,
0.004180636256933212,
0.04431288689374924,
-0.08682861179113388,
-0.051469676196575165,
0.004807619843631983,
-0.059728145599365234,
-0.04778364300727844,
0.03641029819846153,
0.004689944442361593,
0.04511731117963791,
-0.012821067124605179,
0.005485242232680321,
-0.04508203640580177,
0.01990085281431675,
0.011392775923013687,
-0.03173147886991501,
0.029625628143548965,
0.0331600122153759,
0.026791008189320564,
-0.00462872302159667,
-0.011494506150484085,
0.02825905568897724,
0.07265747338533401,
0.020928554236888885,
-3.23056390527654e-8,
0.07844113558530807,
0.018058856949210167,
0.004421486519277096,
-0.003146482165902853,
0.03319248557090759,
0.010291468352079391,
-0.014723062515258789,
-0.02887134440243244,
-0.03863592818379402,
-0.013572813011705875,
0.04477037489414215,
0.005696021020412445,
0.011046333238482475,
0.04580925777554512,
0.0934034138917923,
0.053483787924051285,
-0.010525033809244633,
0.0049337116070091724,
-0.006967725232243538,
-0.009659022092819214,
-0.008164556697010994,
-0.06009691581130028,
0.0007891685818322003,
0.023563163354992867,
0.038248807191848755,
-0.06524094194173813,
0.06983985751867294,
-0.05455315485596657,
0.0036112258676439524,
-0.039400454610586166,
0.0823129266500473,
-0.09595439583063126,
-0.06316470354795456,
0.07204873114824295,
-0.08073465526103973,
0.050254788249731064,
-0.01475839875638485,
-0.004948325455188751,
0.039088279008865356,
0.05560803785920143,
-0.0179277416318655,
-0.08469077944755554,
-0.013963076286017895,
0.014762296341359615,
0.015592982061207294,
0.03014162927865982,
0.03866651654243469,
0.0669373944401741,
-0.08024251461029053,
-0.047404058277606964,
0.012787188403308392,
-0.016618860885500908,
0.029397539794445038,
-0.028710270300507545,
-0.04527830705046654,
0.06386435776948929,
-0.019468050450086594,
0.008377890102565289,
0.10584013164043427,
-0.002120137447491288,
-0.058860257267951965,
-0.07324440032243729,
0.04898177459836006,
-0.028340483084321022
] |
PMID:34232196 | Gastric cancer (GC) is a common cancerous tumor, and is the third leading cause of cancer mortality worldwide. | [
0.022614212706685066,
-0.07205887883901596,
-0.08187979459762573,
-0.01960240676999092,
-0.0002981835277751088,
-0.01781429722905159,
0.05832492187619209,
0.0028112202417105436,
0.040452372282743454,
-0.03516438230872154,
-0.00653236685320735,
0.061631858348846436,
-0.08175259083509445,
-0.035258181393146515,
-0.03394586965441704,
-0.00536013999953866,
0.022567223757505417,
-0.08446326851844788,
-0.029449673369526863,
-0.03885883092880249,
-0.057753536850214005,
0.04722203314304352,
0.12068740278482437,
0.07322511821985245,
-0.015783952549099922,
-0.09292388707399368,
0.01592586189508438,
0.004076501354575157,
-0.052684251219034195,
0.05756140872836113,
-0.004088110756129026,
-0.0709020271897316,
0.017492741346359253,
0.0562005452811718,
0.017407216131687164,
-0.05608789622783661,
-0.019612696021795273,
-0.008308247663080692,
-0.013775990344583988,
0.0451144278049469,
-0.038769952952861786,
-0.061927102506160736,
-0.032384566962718964,
0.012487935833632946,
0.0005623706383630633,
0.015048726461827755,
-0.09386872500181198,
-0.03934134542942047,
-0.030026638880372047,
0.08170440047979355,
0.03284655511379242,
-0.03648004308342934,
-0.144871786236763,
0.041893329471349716,
0.07929088175296783,
-0.03370250388979912,
-0.11882270872592926,
-0.03335367143154144,
0.03472238406538963,
-0.04532909765839577,
-0.0015026851324364543,
0.0037088454701006413,
0.00425146147608757,
0.04078030586242676,
0.026872409507632256,
-0.05389423668384552,
0.057422518730163574,
-0.029861778020858765,
0.015910953283309937,
0.0330326221883297,
0.053463760763406754,
-0.0605134442448616,
-0.008676501922309399,
0.04275035113096237,
-0.08307885378599167,
0.0410257950425148,
-0.01857062056660652,
0.012666676193475723,
0.056495677679777145,
0.07307593524456024,
0.1105378046631813,
0.08973043411970139,
0.0936240702867508,
0.012904846109449863,
-0.06601861864328384,
-0.029818562790751457,
0.00811214093118906,
0.07396312057971954,
0.0029647841583937407,
-0.025967730209231377,
0.007668816950172186,
0.013453876599669456,
0.0594460666179657,
0.016447458416223526,
-0.020272271707654,
-0.08284522593021393,
-0.0017920911777764559,
-0.09900884330272675,
0.02433968521654606,
-0.06154939532279968,
-0.04484421759843826,
-0.06857391446828842,
0.09727873653173447,
0.061625659465789795,
-0.07332062721252441,
0.01665664277970791,
-0.01656026393175125,
0.0839775800704956,
-0.020009450614452362,
-0.0493655651807785,
-0.0745958462357521,
0.11584850400686264,
-0.01415850780904293,
-0.03593069314956665,
-0.07353825867176056,
0.061937835067510605,
-0.0010484934318810701,
-0.05167770013213158,
-0.040261127054691315,
0.056135911494493484,
-0.06311091035604477,
-0.04825878143310547,
0.01781495474278927,
0.07610282301902771,
-0.0037843440659344196,
-0.03573417291045189,
-0.061009731143713,
-1.9732533265704257e-33,
0.026196299120783806,
-0.06536035239696503,
0.12645013630390167,
-0.013528223149478436,
0.0029677371494472027,
0.07589869201183319,
-0.017158502712845802,
-0.09706853330135345,
-0.004547095857560635,
-0.00953572615981102,
0.031228477135300636,
-0.041322238743305206,
0.060132406651973724,
0.007606930565088987,
-0.08911363035440445,
0.07784473150968552,
-0.06844144314527512,
0.030631190165877342,
-0.05379456281661987,
-0.011910063214600086,
-0.03479747101664543,
0.030737856402993202,
0.06641965359449387,
-0.08561939746141434,
-0.01232148613780737,
0.038442086428403854,
-0.10595488548278809,
0.011402647942304611,
0.06883928924798965,
-0.01576831005513668,
0.010028177872300148,
-0.0031121440697461367,
0.0902433693408966,
0.021691225469112396,
-0.03796432539820671,
0.01653221808373928,
-0.02973758615553379,
-0.06935788691043854,
0.0846020057797432,
0.03345377743244171,
-0.04783638194203377,
-0.07072282582521439,
0.01343531720340252,
-0.019671807065606117,
0.016423547640442848,
-0.04803498461842537,
-0.048505596816539764,
0.06570515036582947,
-0.06514711678028107,
0.04106021672487259,
0.0329585000872612,
-0.06002000346779823,
-0.07068254053592682,
0.07368496060371399,
0.03614640608429909,
-0.005200142506510019,
-0.055900972336530685,
0.034216172993183136,
-0.029056480154395103,
0.03972309082746506,
0.030563581734895706,
0.04311655834317207,
-0.026123108342289925,
0.04176885262131691,
0.009066556580364704,
-0.01281264703720808,
-0.0886683464050293,
-0.03216201066970825,
0.03353848308324814,
0.03678576648235321,
0.008974325843155384,
-0.03006022982299328,
0.05347876995801926,
0.03988289460539818,
0.020852921530604362,
-0.0835137888789177,
0.03214143216609955,
0.03605237230658531,
-0.04763444885611534,
0.08301208168268204,
-0.03722166642546654,
-0.042189646512269974,
0.021397653967142105,
0.04266105592250824,
-0.08328738063573837,
0.015760108828544617,
-0.05677931383252144,
-0.08217509835958481,
-0.013267462141811848,
0.14136432111263275,
-0.08105868846178055,
0.003458119463175535,
0.02305210940539837,
0.0855211466550827,
0.018823526799678802,
-5.505455342725031e-35,
0.03323753923177719,
0.013631153851747513,
-0.004023453686386347,
0.030805451795458794,
0.08467874675989151,
-0.024998638778924942,
-0.0035566010046750307,
-0.13669486343860626,
-0.03388235345482826,
0.03476305305957794,
0.05496196821331978,
0.15345923602581024,
0.02285175397992134,
-0.000811051984783262,
0.038866400718688965,
-0.03552134707570076,
0.025278309360146523,
-0.051050782203674316,
-0.03227315470576286,
-0.003500844817608595,
0.0216531939804554,
-0.03429749608039856,
-0.05211750417947769,
-0.0700940266251564,
-0.09804221987724304,
0.017729638144373894,
0.014639209024608135,
0.010244354605674744,
-0.0355626679956913,
-0.04243334010243416,
0.00507286237552762,
0.07751355320215225,
-0.039511967450380325,
-0.006878115236759186,
0.10456818342208862,
-0.053596314042806625,
0.0097820358350873,
-0.03374028950929642,
-0.004044670611619949,
-0.06365547329187393,
-0.021244194358587265,
0.058337341994047165,
-0.008012798614799976,
-0.02552092634141445,
0.013552101328969002,
0.04120827838778496,
0.14477254450321198,
0.0296544898301363,
0.11287393420934677,
-0.028244569897651672,
-0.03479260951280594,
-0.01645672135055065,
-0.0537884347140789,
0.02939835749566555,
0.05303819477558136,
0.10682250559329987,
-0.030924977734684944,
-0.055278629064559937,
0.014971647411584854,
0.017061905935406685,
0.027066197246313095,
0.00743824103847146,
0.0531921312212944,
-0.001793742529116571,
0.06506272405385971,
0.0119343725964427,
0.07503566890954971,
0.02569320797920227,
0.04095401242375374,
0.050591759383678436,
0.007940038107335567,
-0.01348295621573925,
-0.06182511895895004,
0.04604201763868332,
-0.06517220288515091,
-0.025484709069132805,
0.04774695634841919,
0.03952318802475929,
0.040954943746328354,
-0.027514824643731117,
0.052005864679813385,
-0.03762098029255867,
0.022140223532915115,
-0.05040714889764786,
0.049632009118795395,
0.05219646915793419,
-0.06366471946239471,
0.06480226665735245,
0.006317697465419769,
0.021997570991516113,
-0.07759701460599899,
-0.02938883937895298,
0.02243855409324169,
-0.030949126929044724,
0.007434835657477379,
-2.4415038879510575e-8,
-0.01999962516129017,
-0.0357515923678875,
-0.04002327844500542,
-0.06138576939702034,
0.009615961462259293,
0.009196228347718716,
0.008004462346434593,
0.0482574962079525,
0.039061546325683594,
0.019844695925712585,
0.005767012480646372,
0.05985245853662491,
-0.014764642342925072,
-0.06561759859323502,
-0.03486097231507301,
0.012279856018722057,
-0.04915895313024521,
-0.00540793826803565,
0.012806071899831295,
0.008394068107008934,
-0.07073844969272614,
-0.03456723690032959,
0.05462529510259628,
-0.02166846953332424,
-0.07515662908554077,
-0.047097112983465195,
0.08713524043560028,
0.14537256956100464,
-0.039842505007982254,
-0.005737996194511652,
0.061254922300577164,
-0.020555688068270683,
0.03674817830324173,
-0.017798565328121185,
0.006556345149874687,
-0.002381428610533476,
0.017428811639547348,
0.028987132012844086,
0.01411113515496254,
0.016367679461836815,
-0.0011292516719549894,
0.10306163132190704,
0.025549892336130142,
-0.0005763162625953555,
-0.04454302787780762,
0.013257957994937897,
-0.05344323068857193,
0.021244358271360397,
-0.036116547882556915,
0.06882651150226593,
-0.022677727043628693,
-0.033191975206136703,
-0.033657852560281754,
0.012537253089249134,
0.03160594031214714,
-0.01701945997774601,
0.00785815715789795,
0.020709075033664703,
0.05070345103740692,
-0.023746386170387268,
-0.06104336306452751,
-0.05627492442727089,
0.049472369253635406,
0.03478609025478363
] |
PMID:34232196 | Although comprehensive therapies of GC have been widely used in clinical set ups, advanced gastric cancer carries is characterized by poor prognosis, probably due to lack of effective prognostic biomarkers. | [
0.003671554382890463,
-0.07776479423046112,
-0.07097259163856506,
-0.004417234566062689,
0.014053563587367535,
-0.06275616586208344,
-0.005324978847056627,
0.0356825552880764,
0.03153132647275925,
-0.06509874761104584,
-0.0013939744094386697,
0.07334557175636292,
-0.07913199067115784,
-0.016003305092453957,
-0.016529373824596405,
0.028300540521740913,
0.054662302136421204,
-0.05375001206994057,
-0.030744407325983047,
-0.11061975359916687,
-0.0911124125123024,
0.012967193499207497,
0.1340062916278839,
0.0911594033241272,
-0.0016977455234155059,
-0.10341516137123108,
-0.018536191433668137,
0.005810726899653673,
-0.04170786589384079,
0.06997469812631607,
-0.020381690934300423,
-0.06378226727247238,
-0.010324902832508087,
0.05679888650774956,
-0.021386481821537018,
-0.06055835634469986,
-0.021009771153330803,
-0.006147043779492378,
-0.006627938244491816,
0.033596232533454895,
0.029817990958690643,
-0.045673567801713943,
-0.06824270635843277,
-0.012586647644639015,
0.005596761126071215,
-0.05226818099617958,
-0.05777807906270027,
-0.007429835852235556,
-0.0499282069504261,
0.07582008838653564,
-0.006271002348512411,
-0.04390254244208336,
-0.07567444443702698,
-0.011337293311953545,
0.023635201156139374,
0.027529962360858917,
-0.08816101402044296,
-0.03002581186592579,
0.0499582402408123,
-0.08827539533376694,
-0.003315485082566738,
-0.03245704993605614,
0.007680550683289766,
0.013302067294716835,
0.04632028937339783,
-0.0783933475613594,
0.0676204115152359,
-0.030143048614263535,
0.003727346658706665,
0.031502529978752136,
0.015855377539992332,
-0.01738886348903179,
-0.012295537628233433,
0.06694342195987701,
-0.06821252405643463,
0.03492606803774834,
-0.02493993006646633,
0.025805655866861343,
0.009281344711780548,
0.07876334339380264,
0.09500972926616669,
0.023832350969314575,
0.09390343725681305,
0.0025268099270761013,
-0.025680802762508392,
-0.020635614171624184,
0.017496224492788315,
0.09660559892654419,
-0.02579655312001705,
-0.03765270486474037,
0.043587785214185715,
-0.029780620709061623,
0.037605904042720795,
0.020368725061416626,
-0.005246741231530905,
-0.0894203782081604,
-0.009993864223361015,
-0.0657191202044487,
-0.010902591049671173,
-0.07072876393795013,
-0.06444523483514786,
-0.05736272782087326,
0.05372222140431404,
0.010693666525185108,
-0.059340208768844604,
0.0061076488345861435,
0.009781727567315102,
0.07013418525457382,
0.006743549834936857,
-0.04350635036826134,
0.005052828695625067,
0.05663435161113739,
0.012623684480786324,
0.0009910105727612972,
-0.08779317885637283,
0.08725834637880325,
-0.06874760240316391,
-0.034472379833459854,
-0.028577299788594246,
0.046621933579444885,
-0.053548622876405716,
-0.04387733340263367,
0.057394713163375854,
0.05421432852745056,
0.008587167598307133,
0.044779058545827866,
-0.02843513898551464,
3.5544142676103386e-33,
0.026231730356812477,
-0.06002839282155037,
0.08603236824274063,
0.032210975885391235,
0.0032912830356508493,
0.06307408958673477,
-0.016175050288438797,
-0.10850796103477478,
0.04529808089137077,
-0.01343207061290741,
0.02303566038608551,
0.017773881554603577,
0.051546309143304825,
0.02325741946697235,
-0.10187242180109024,
0.05572343245148659,
-0.009457463398575783,
0.0006446656188927591,
-0.07928522676229477,
0.0040016137063503265,
0.00599150825291872,
0.016250282526016235,
0.06622576713562012,
-0.15440605580806732,
0.02397790737450123,
0.03301471844315529,
-0.04433343932032585,
0.07230944186449051,
0.0029358856845647097,
-0.01623716950416565,
-0.028423026204109192,
-0.015837078914046288,
0.13441817462444305,
0.015832513570785522,
-0.03448960930109024,
-0.010375745594501495,
-0.008667154237627983,
-0.07543919235467911,
0.1325894296169281,
0.05588816478848457,
-0.034865621477365494,
-0.004166231025010347,
0.003123765578493476,
-0.07171571254730225,
0.008018869906663895,
-0.05650709569454193,
-0.03000553324818611,
0.025880297645926476,
-0.07202589511871338,
0.05226709693670273,
0.07274247705936432,
-0.054716337472200394,
-0.11440559476613998,
0.05435029789805412,
-0.015913542360067368,
-0.010023397393524647,
-0.07425916194915771,
0.01716463454067707,
0.020090242847800255,
0.008501293137669563,
0.022958548739552498,
0.01615097187459469,
-0.056536827236413956,
0.017322316765785217,
-0.022199004888534546,
0.05510568991303444,
-0.09622447192668915,
0.00328847486525774,
-0.025562727823853493,
0.06608273088932037,
-0.005717135034501553,
-0.03972131758928299,
0.08555140346288681,
0.018158605322241783,
0.06755015254020691,
-0.10625836998224258,
0.027946973219513893,
0.04829961434006691,
-0.03255961835384369,
0.09928127378225327,
-0.013094563968479633,
-0.035850752145051956,
-0.015838736668229103,
0.14336442947387695,
-0.05366397276520729,
-0.027767319232225418,
-0.05959229916334152,
-0.017712561413645744,
-0.02553538605570793,
0.10784570127725601,
-0.06957393884658813,
0.013484287075698376,
0.010720301419496536,
0.07937288284301758,
0.035318225622177124,
-4.738428381082195e-33,
-0.006205153185874224,
0.03091544471681118,
-0.019740253686904907,
0.035532087087631226,
0.07528340816497803,
-0.004506275989115238,
-0.010473445057868958,
-0.16412585973739624,
0.00623693922534585,
-0.057950783520936966,
0.05661648511886597,
0.11662528663873672,
0.01643534004688263,
-0.005232203286141157,
0.007863075472414494,
-0.02300185151398182,
-0.04550508037209511,
-0.048430003225803375,
-0.012258611619472504,
0.018635733053088188,
0.04730009287595749,
-0.04350036755204201,
-0.06135993450880051,
-0.05716034024953842,
-0.08294540643692017,
0.027226924896240234,
0.06337475031614304,
0.030902797356247902,
-0.004171829205006361,
-0.0943375825881958,
0.008611693978309631,
0.046684782952070236,
-0.05699504166841507,
-0.0283818319439888,
0.08955632150173187,
-0.04004378616809845,
0.03599747270345688,
-0.03985029458999634,
-0.013491246849298477,
-0.03578302264213562,
-0.05408499017357826,
0.06047181040048599,
-0.0417555496096611,
-0.05419902130961418,
-0.0034619183279573917,
0.0404876247048378,
0.10726679861545563,
-0.04045204818248749,
0.09505410492420197,
-0.03253953158855438,
0.01351846382021904,
-0.030341772362589836,
-0.04920283332467079,
0.019982365891337395,
0.04607405886054039,
0.06021755188703537,
-0.04526785761117935,
-0.04751820117235184,
-0.011405342258512974,
0.03414240479469299,
-0.04978420212864876,
-0.0021285340189933777,
0.1369154453277588,
0.03282417729496956,
0.027802636846899986,
0.03951888531446457,
0.07901022583246231,
0.03539546951651573,
0.021280359476804733,
0.07429984956979752,
-0.004280828405171633,
-0.024880576878786087,
-0.07128700613975525,
0.0454256571829319,
0.0006106987711973488,
0.026987837627530098,
-0.007067088503390551,
0.024240238592028618,
0.04565945267677307,
-0.03308527544140816,
0.02266448363661766,
-0.03820040449500084,
-0.026627423241734505,
-0.07542595267295837,
0.11801112443208694,
0.11498186737298965,
-0.08177604526281357,
0.03005388006567955,
0.03459177538752556,
0.0021086556371301413,
-0.03275390714406967,
-0.060524214059114456,
0.050265099853277206,
-0.02204984240233898,
0.006917779333889484,
-3.248401014843694e-8,
-0.004131790716201067,
-0.03313323110342026,
-0.015106040984392166,
-0.057574234902858734,
0.014190679416060448,
0.011592980474233627,
-0.04021922126412392,
0.04516872391104698,
0.023484546691179276,
0.01011498924344778,
0.045653294771909714,
-0.005393432453274727,
-0.019779738038778305,
-0.05188845470547676,
-0.022042931988835335,
0.011135206557810307,
-0.04205644503235817,
0.055479906499385834,
0.0031897928565740585,
0.05846862867474556,
-0.07522492110729218,
-0.017653288319706917,
0.0440489761531353,
-0.06441499292850494,
-0.0323476605117321,
-0.03385919705033302,
0.054425157606601715,
0.09576559066772461,
-0.03202676773071289,
-0.0077860355377197266,
0.005866572726517916,
-0.02200305461883545,
0.0922330841422081,
0.01959802582859993,
0.0496431365609169,
-0.01263488084077835,
0.05108985677361488,
0.08457692712545395,
-0.014498108066618443,
0.05471425503492355,
-0.008545898832380772,
0.04492341727018356,
0.024710141122341156,
0.0027236556634306908,
-0.033734988421201706,
-0.02100784331560135,
-0.03480450063943863,
0.031854234635829926,
-0.04079108685255051,
0.03126893937587738,
-0.029456548392772675,
-0.030744845047593117,
-0.0158231221139431,
0.01964661106467247,
0.057127662003040314,
0.014482258819043636,
-0.025987567380070686,
-0.003061424009501934,
0.031037071719765663,
-0.046408895403146744,
-0.06424859166145325,
-0.07534905523061752,
-0.016557196155190468,
0.017545703798532486
] |
PMID:34232196 | Mammalian histone deacetylase family, histone deacetylases (HDACs), play significant roles in initiation and progression of tumors. | [
-0.05241279676556587,
-0.017815951257944107,
-0.029894739389419556,
-0.03199430927634239,
-0.08657782524824142,
-0.017947832122445107,
0.009352422319352627,
-0.06941729784011841,
-0.08364817500114441,
0.0005900339456275105,
-0.013678818941116333,
0.00699709914624691,
0.016896937042474747,
0.04217193275690079,
0.010904592461884022,
0.03411242365837097,
-0.09819915890693665,
-0.06251318752765656,
-0.04318176954984665,
-0.01943252794444561,
-0.05526302382349968,
0.00726959016174078,
0.05823370814323425,
0.02360004000365734,
0.007583875674754381,
-0.051740724593400955,
0.06773629039525986,
0.06171762943267822,
-0.060172587633132935,
-0.06571479886770248,
-0.013090022839605808,
-0.12659791111946106,
0.047172002494335175,
0.023509444668889046,
0.07759137451648712,
0.005891387350857258,
-0.04195886477828026,
0.06681282818317413,
-0.004482481628656387,
-0.01576177403330803,
0.08412144333124161,
-0.021002361550927162,
-0.015963729470968246,
0.057241056114435196,
-0.026191242039203644,
-0.09811902791261673,
-0.10655803233385086,
-0.08548881113529205,
0.03197372704744339,
0.10048886388540268,
-0.015580592676997185,
0.06264510005712509,
0.025965705513954163,
0.006956261117011309,
0.04101158678531647,
0.06192774325609207,
0.0026622761506587267,
-0.01882677897810936,
0.030522545799613,
-0.07364436239004135,
-0.019752539694309235,
-0.09442414343357086,
-0.04667947441339493,
-0.009432473219931126,
0.05513983592391014,
-0.017466118559241295,
0.11818183213472366,
-0.033911917358636856,
-0.004740622825920582,
0.005256681237369776,
-0.0022859848104417324,
-0.04664454981684685,
0.016451168805360794,
0.12157092988491058,
0.023775378242135048,
-0.06557558476924896,
0.03907741233706474,
0.011374578811228275,
-0.03766799345612526,
-0.0569562092423439,
0.011991467326879501,
-0.013745984062552452,
0.09749273955821991,
0.07846769690513611,
-0.022421320900321007,
0.0130072683095932,
-0.027643466368317604,
-0.05887962505221367,
0.013550182804465294,
0.03179454430937767,
-0.01144300028681755,
-0.06476404517889023,
-0.01769803650677204,
0.009611368179321289,
0.017825933173298836,
0.00011899944365723059,
0.07271721959114075,
0.042930103838443756,
-0.03707866743206978,
-0.026517556980252266,
0.03113924153149128,
-0.0527152456343174,
-0.08468609303236008,
-0.055510420352220535,
0.0059417192824184895,
0.07818420231342316,
-0.03539687395095825,
0.026543965563178062,
-0.04810650646686554,
-0.0011813478777185082,
0.018298445269465446,
0.0039480458945035934,
0.00833812914788723,
0.0542537197470665,
-0.007092547602951527,
0.09036547690629959,
0.002251596422865987,
-0.014829438179731369,
0.04224085807800293,
-0.10549334436655045,
0.015396044589579105,
0.02693091332912445,
0.059908319264650345,
0.010401133447885513,
-0.0728180930018425,
-0.02977079711854458,
-0.11173737794160843,
-6.300060136522127e-34,
-0.02290397882461548,
0.02539788745343685,
-0.06374248117208481,
0.02508074790239334,
-0.003490642411634326,
-0.03665840998291969,
-0.07363928109407425,
0.0684310644865036,
-0.025082502514123917,
-0.10817223787307739,
0.01977303810417652,
0.06485703587532043,
0.01140674576163292,
-0.004720898345112801,
-0.09083695709705353,
-0.029693758115172386,
0.03718649223446846,
0.05942995846271515,
-0.017118146643042564,
-0.046831779181957245,
-0.11731397360563278,
0.07984176278114319,
-0.00019035582954529673,
-0.03831174597144127,
-0.0012197501491755247,
-0.0012977763544768095,
-0.05554617568850517,
0.0825662687420845,
0.031423911452293396,
0.018557803705334663,
-0.028535854071378708,
0.02193281799554825,
0.016498658806085587,
0.04030327871441841,
0.027122190222144127,
0.04846519976854324,
0.01286446861922741,
-0.029944835230708122,
0.10418503731489182,
0.0747048556804657,
0.03948049247264862,
-0.044105492532253265,
-0.021717658266425133,
-0.08493101596832275,
-0.019387569278478622,
-0.06187785044312477,
-0.06158112734556198,
-0.0016153231263160706,
-0.0686771497130394,
0.02960650809109211,
0.0065499646589159966,
-0.028601722791790962,
0.054030515253543854,
0.04778865724802017,
-0.008921023458242416,
-0.017910828813910484,
-0.03251674026250839,
-0.03219933807849884,
0.077354796230793,
0.04205981269478798,
-0.002006657188758254,
-0.02080586925148964,
0.02147582918405533,
0.09192422777414322,
0.02351457253098488,
-0.0589892715215683,
-0.09609944373369217,
0.0008136245305649936,
-0.07593847811222076,
-0.0008232553373090923,
0.05026308447122574,
0.03307364881038666,
0.09004601091146469,
-0.07034876942634583,
0.0068574571050703526,
-0.016962360590696335,
-0.0568583644926548,
0.09996982663869858,
-0.09527235478162766,
0.13357482850551605,
0.06644073873758316,
-0.03434053063392639,
-0.07738988846540451,
-0.00400469871237874,
-0.027309928089380264,
-0.01306888647377491,
0.0790301263332367,
-0.0609450526535511,
-0.04466898739337921,
0.01363272313028574,
-0.04210014268755913,
-0.025425605475902557,
0.03636632859706879,
-0.038573067635297775,
0.08542390912771225,
-2.5784898375408896e-33,
0.09619984775781631,
0.032858990132808685,
0.08471326529979706,
0.009696416556835175,
0.012932553887367249,
0.009992027655243874,
0.12290902435779572,
0.007966004312038422,
0.007939702831208706,
0.02897421270608902,
0.07230660319328308,
0.02134571596980095,
-0.024583155289292336,
-0.12624621391296387,
-0.001127913361415267,
0.015950733795762062,
0.025357665494084358,
0.04408804699778557,
-0.01630270481109619,
-0.04952395334839821,
-0.005654489155858755,
0.06400029361248016,
-0.11279609799385071,
0.07804575562477112,
0.017874279990792274,
-0.029048820957541466,
-0.06764432042837143,
0.08391255885362625,
0.00004750960215460509,
0.0071464343927800655,
-0.05740033835172653,
0.057956162840127945,
0.019268831238150597,
-0.027688298374414444,
0.037189871072769165,
0.031211504712700844,
-0.0344233512878418,
-0.023033376783132553,
-0.09452370554208755,
-0.05096570402383804,
-0.058689117431640625,
0.034587562084198,
-0.02847464755177498,
0.06516183912754059,
0.016503529623150826,
0.11728529632091522,
0.04762905091047287,
0.11757947504520416,
-0.008517904207110405,
-0.0007172793848440051,
0.07135224342346191,
-0.013566815294325352,
0.007399975787848234,
0.025945279747247696,
-0.015416649170219898,
0.016408007591962814,
0.08081503957509995,
0.04370088502764702,
-0.017008552327752113,
0.02794066071510315,
-0.05125661939382553,
0.024548206478357315,
-0.002821847330778837,
0.05790342018008232,
-0.019524825736880302,
0.017863035202026367,
-0.0862424373626709,
-0.037531740963459015,
0.02119026891887188,
0.06776617467403412,
-0.012545781210064888,
-0.01407310739159584,
0.013469472527503967,
0.021620040759444237,
-0.03607458993792534,
0.08355909585952759,
-0.03566272184252739,
-0.03598637506365776,
0.01882557012140751,
-0.021981779485940933,
0.005916432477533817,
-0.018467027693986893,
0.03444874286651611,
0.008202465251088142,
-0.02491736225783825,
-0.0563976876437664,
-0.03038588911294937,
-0.006373682525008917,
-0.07867667078971863,
0.021508943289518356,
0.01065574586391449,
-0.08670931309461594,
-0.06565524637699127,
0.032293595373630524,
-0.009745541028678417,
-2.542169497132818e-8,
0.05655449256300926,
-0.09124191105365753,
0.039673324674367905,
-0.07479072362184525,
0.008978314697742462,
-0.00572368735447526,
0.034722741693258286,
0.07907639443874359,
0.08119690418243408,
-0.05461809039115906,
-0.015179308131337166,
0.0107202660292387,
0.014029010199010372,
-0.013426988385617733,
-0.06495541334152222,
-0.045953862369060516,
0.051214080303907394,
0.06985799968242645,
-0.02339586615562439,
-0.026075342670083046,
-0.026569364592432976,
-0.016001015901565552,
-0.014896140433847904,
0.023312054574489594,
-0.0362812839448452,
0.008378998376429081,
-0.02716713584959507,
0.05124090239405632,
0.02134520374238491,
-0.08343906700611115,
0.05775768309831619,
-0.06402672827243805,
0.043688904494047165,
-0.04441600292921066,
0.02472524344921112,
0.029113447293639183,
0.05997764319181442,
-0.06965566426515579,
0.024159325286746025,
0.003034873167052865,
0.05237732455134392,
0.05492834746837616,
-0.06031117960810661,
-0.021586105227470398,
-0.0720074400305748,
-0.040152642875909805,
-0.034903548657894135,
0.04020337387919426,
-0.014805275946855545,
-0.041578929871320724,
-0.05861872062087059,
0.026028640568256378,
-0.03674883022904396,
-0.0951385423541069,
-0.03957050293684006,
0.02203589491546154,
-0.04656160995364189,
0.038731154054403305,
-0.028706703335046768,
0.044076815247535706,
0.0834287703037262,
0.04935059696435928,
0.10545410215854645,
-0.04679970070719719
] |
PMID:34232196 | Aberrant expression of HDACs is reported in many cancer types including gastric cancer, and may serve as candidate biomarkers or therapeutic targets for GC patients.Gene Expression Profiling Interactive Analysis was used to explore mRNA levels of HDACs in GC. | [
-0.036472465842962265,
-0.09085244685411453,
-0.0479973666369915,
-0.025775188580155373,
0.027520248666405678,
-0.009972812607884407,
0.02513861283659935,
-0.020136965438723564,
-0.0018486703047528863,
-0.03643091022968292,
-0.04599250853061676,
-0.01655580848455429,
-0.032663971185684204,
-0.015420214273035526,
0.006437099073082209,
0.018318582326173782,
-0.09431689977645874,
-0.025263849645853043,
-0.02105138823390007,
-0.06164177507162094,
0.0036858106032013893,
0.04298747330904007,
0.07041725516319275,
0.10634269565343857,
0.038050148636102676,
-0.07254361361265182,
0.09504266083240509,
0.029372477903962135,
-0.051016151905059814,
0.06723335385322571,
-0.01524300780147314,
-0.09210114181041718,
0.09085080772638321,
0.06182391941547394,
0.05864786356687546,
-0.026813911274075508,
-0.057394325733184814,
0.010273858904838562,
-0.007864991202950478,
-0.03470659255981445,
0.0638882964849472,
-0.05716289207339287,
0.007195471785962582,
0.03005802258849144,
0.0636652410030365,
-0.08585996925830841,
-0.0401625856757164,
-0.03685198351740837,
0.009012587368488312,
0.157778799533844,
0.03786933049559593,
0.008764025755226612,
-0.03925728425383568,
-0.026028281077742577,
0.027067823335528374,
0.0457003228366375,
-0.027827274054288864,
-0.06289806216955185,
0.09670888632535934,
-0.059912580996751785,
0.0038931427989155054,
-0.07244104892015457,
0.01734246499836445,
-0.014505717903375626,
0.060546644032001495,
-0.056871190667152405,
0.059582408517599106,
-0.010750697925686836,
-0.0326496958732605,
-0.03907162323594093,
-0.044323720037937164,
-0.049374792724847794,
-0.02763313241302967,
0.11240388453006744,
0.05737128481268883,
-0.04233567789196968,
0.007081667892634869,
-0.04920487850904465,
0.03851683437824249,
-0.022736890241503716,
0.07345347106456757,
-0.015425926074385643,
0.07216941565275192,
0.10283173620700836,
-0.050632182508707047,
0.07206062972545624,
0.01865820586681366,
0.019523294642567635,
0.005960344802588224,
0.005543780513107777,
0.04727479815483093,
-0.0572756826877594,
0.06471923738718033,
-0.0396592915058136,
-0.006608408410102129,
-0.05864051729440689,
0.010315660387277603,
-0.006443424616008997,
0.06259345263242722,
-0.09151732921600342,
0.015517587773501873,
-0.02725699543952942,
-0.03248593583703041,
-0.07213768362998962,
-0.08024854212999344,
0.043899476528167725,
0.018409106880426407,
0.07066985964775085,
-0.053811799734830856,
-0.01221715658903122,
0.0013340759323909879,
0.03607071191072464,
0.02785579487681389,
-0.015236658044159412,
-0.03362471982836723,
0.027326077222824097,
0.028577981516718864,
-0.11160992830991745,
-0.08877119421958923,
-0.04834454879164696,
-0.04372687637805939,
-0.07261068373918533,
0.07668710500001907,
-0.01594945415854454,
0.011491580866277218,
0.011399677023291588,
-0.08791705220937729,
2.76332805901304e-33,
0.037484776228666306,
-0.025194918736815453,
-0.012517949566245079,
0.03135298565030098,
0.0027937039267271757,
-0.04106372222304344,
-0.026170678436756134,
-0.061230167746543884,
-0.021439790725708008,
0.01719585992395878,
-0.007916321977972984,
0.019510542973876,
0.01250843983143568,
-0.01507321186363697,
-0.10626385360956192,
0.007792177144438028,
0.02688446268439293,
0.007478408981114626,
-0.08707946538925171,
-0.039856091141700745,
-0.06207409128546715,
0.06669774651527405,
0.03923308104276657,
-0.15623807907104492,
0.026504606008529663,
-0.015764407813549042,
-0.07026156038045883,
0.049808356910943985,
0.05418085306882858,
0.0013632364571094513,
-0.06548400223255157,
-0.009962075389921665,
0.09207722544670105,
0.010974652133882046,
0.07023540139198303,
0.023723453283309937,
0.019261976704001427,
-0.05493714660406113,
0.10285378992557526,
0.07332804799079895,
-0.0038717780262231827,
-0.016526799649000168,
0.0014178786659613252,
-0.061659909784793854,
0.005539190489798784,
0.00025126853142865,
-0.03972126916050911,
0.084476038813591,
-0.08873841166496277,
0.06983949989080429,
0.01980203203856945,
-0.05043046176433563,
0.038044221699237823,
0.042568717151880264,
0.019923798739910126,
0.016151655465364456,
-0.08452367782592773,
-0.05482272431254387,
0.04751051962375641,
0.10204792022705078,
-0.023944532498717308,
0.05931750312447548,
-0.034549884498119354,
0.03638659417629242,
-0.00038655969547107816,
-0.030083784833550453,
-0.09126622974872589,
-0.009646995924413204,
0.019203409552574158,
0.09662686288356781,
0.06459686905145645,
0.0035919833462685347,
0.07164714485406876,
-0.02652592398226261,
0.0291697196662426,
-0.06281329691410065,
-0.020591668784618378,
0.14974215626716614,
-0.0642135739326477,
0.0847494900226593,
0.010239626280963421,
-0.07042121887207031,
0.04167328029870987,
0.1095496416091919,
-0.027020970359444618,
-0.045810766518116,
0.03253598138689995,
-0.06734015792608261,
-0.10548011213541031,
0.06322575360536575,
-0.017974765971302986,
-0.009133925661444664,
0.030997969210147858,
-0.01631585694849491,
0.037300098687410355,
-3.403310713625872e-33,
-0.014708305709064007,
0.040646933019161224,
-0.0037591613363474607,
-0.02607019990682602,
0.0289032980799675,
-0.0113650131970644,
0.008414271287620068,
-0.11804968118667603,
0.010060491040349007,
-0.02130056545138359,
0.15559791028499603,
0.055320288985967636,
0.026325926184654236,
-0.10975181311368942,
0.027737285941839218,
0.026858270168304443,
-0.011028649285435677,
0.01134494598954916,
-0.07065010815858841,
0.026404621079564095,
0.009146343916654587,
-0.026958296075463295,
-0.028321510180830956,
0.004926722031086683,
-0.06730227172374725,
-0.011040396988391876,
0.07903320342302322,
0.09747254103422165,
0.01668613590300083,
-0.036064717918634415,
-0.05714038386940956,
0.06801886111497879,
-0.04244925081729889,
-0.03459900617599487,
0.022552473470568657,
-0.07496463507413864,
0.05347982794046402,
-0.044170185923576355,
-0.022725887596607208,
-0.04257616773247719,
-0.06628219783306122,
0.05958639830350876,
-0.059689152985811234,
0.004425788298249245,
0.007652174215763807,
0.07235316187143326,
0.05554211512207985,
0.01496791560202837,
0.04847969114780426,
-0.03480314463376999,
0.03854933753609657,
-0.05449661239981651,
0.02684471197426319,
0.04741142690181732,
0.014859750866889954,
0.0010349077638238668,
0.026974299922585487,
0.04988608881831169,
0.007902291603386402,
0.0027931458316743374,
-0.062392961233854294,
0.008057141676545143,
0.019699878990650177,
0.04483834654092789,
0.06649141758680344,
-0.032320085912942886,
-0.0023808300029486418,
-0.07893326878547668,
-0.008044746704399586,
-0.030897753313183784,
0.054529234766960144,
-0.035446301102638245,
0.009801069274544716,
0.03506083786487579,
-0.062184516340494156,
-0.0009347728919237852,
-0.052245549857616425,
-0.006329500116407871,
0.06928253918886185,
0.04038907587528229,
0.022999122738838196,
-0.013819387182593346,
0.010768554173409939,
0.005843938793987036,
0.0483568049967289,
0.041775353252887726,
-0.08270884305238724,
0.03996025770902634,
-0.03320077806711197,
0.0003636455221567303,
-0.031447917222976685,
-0.015493529848754406,
-0.022441504523158073,
-0.0025007750373333693,
-0.04171358048915863,
-2.842087631904633e-8,
-0.04302951321005821,
-0.09398163855075836,
-0.020703960210084915,
-0.10136652737855911,
-0.016454389318823814,
0.07253970950841904,
-0.057955168187618256,
0.0738234594464302,
0.07269737124443054,
0.013364791870117188,
0.06629232317209244,
0.003823429113253951,
-0.06549765169620514,
-0.0674213171005249,
-0.0004316869017202407,
0.010975987650454044,
-0.013963557779788971,
0.0600915253162384,
-0.022500842809677124,
0.011195328086614609,
-0.06313270330429077,
0.049142129719257355,
-0.008731523528695107,
0.029340390115976334,
-0.020165354013442993,
-0.04185759648680687,
0.017102055251598358,
0.031863223761320114,
0.02666570618748665,
-0.06289605051279068,
0.021791979670524597,
-0.07312371581792831,
0.07145442068576813,
-0.03562347963452339,
0.021941736340522766,
0.027349768206477165,
0.015829574316740036,
-0.01679769717156887,
-0.01686975732445717,
0.14244778454303741,
0.029574040323495865,
0.04877758398652077,
-0.04410768672823906,
-0.026143955066800117,
-0.059486571699380875,
-0.018810702487826347,
-0.004404539708048105,
0.010999631136655807,
-0.014165430329740047,
-0.03332282230257988,
-0.01980360969901085,
-0.05178381875157356,
0.0064061954617500305,
-0.056281134486198425,
0.07291316241025925,
-0.027505042031407356,
-0.018710995092988014,
0.050202880054712296,
0.08660168200731277,
0.06467071920633316,
0.01307697407901287,
0.05714501813054085,
0.03320405259728432,
0.02157161943614483
] |
PMID:34232196 | Kaplan-Meier plotter was used to determine the prognostic value of HDACs mRNA expression in GC. | [
-0.09023173898458481,
-0.11167208850383759,
-0.060626063495874405,
-0.032358285039663315,
0.00033889253973029554,
0.018016723915934563,
-0.0385594479739666,
0.09258272498846054,
-0.001305344165302813,
0.05213547125458717,
-0.0009833461372181773,
-0.0015041808364912868,
0.008529916405677795,
-0.011258035898208618,
-0.04703652113676071,
-0.02060031332075596,
-0.10350064188241959,
-0.07603726536035538,
-0.027688998728990555,
-0.06283540278673172,
-0.0007267229375429451,
0.03965793550014496,
-0.010336322709918022,
0.08035547286272049,
0.021799754351377487,
-0.036265235394239426,
0.02916201949119568,
-0.02381458319723606,
-0.02845887467265129,
0.029587967321276665,
-0.017027126625180244,
-0.024203486740589142,
0.10815051198005676,
0.040603574365377426,
0.03789817541837692,
0.026703134179115295,
-0.08177399635314941,
-0.05174214020371437,
0.01918272115290165,
-0.05547511205077171,
0.09439163655042648,
-0.020497605204582214,
0.013947021216154099,
0.03266868740320206,
0.030816618353128433,
-0.0583711601793766,
-0.025055503472685814,
-0.042786650359630585,
0.030959658324718475,
0.11501211673021317,
0.022851280868053436,
-0.0031028320081532,
-0.044314175844192505,
-0.034943703562021255,
0.05900029093027115,
0.06496380269527435,
-0.04926362633705139,
-0.10092197358608246,
0.12186086922883987,
0.014649526216089725,
-0.10732867568731308,
-0.07527320832014084,
0.020967740565538406,
-0.039963606745004654,
0.09878429025411606,
-0.016254207119345665,
0.09829475730657578,
0.029707301408052444,
-0.02523752674460411,
-0.0011319791665300727,
-0.033115316182374954,
-0.024550780653953552,
-0.04571257904171944,
0.06777205318212509,
0.019486108794808388,
-0.002703289268538356,
-0.021245216950774193,
-0.04546481743454933,
0.024858105927705765,
-0.03452713415026665,
-0.0008006494026631117,
0.03230801969766617,
0.07702890038490295,
0.06742431223392487,
-0.030418390408158302,
0.1030196025967598,
0.04698202386498451,
-0.009950533509254456,
0.006071330048143864,
0.03377729654312134,
0.07651270180940628,
-0.04466311261057854,
0.016477961093187332,
-0.010974092409014702,
-0.042591024190187454,
0.0199271310120821,
0.009817635640501976,
0.060748156160116196,
0.05426900461316109,
-0.0900467187166214,
0.028648434206843376,
-0.031939513981342316,
-0.005504587199538946,
-0.08580826222896576,
-0.05915430188179016,
-0.00712572829797864,
0.019197732210159302,
0.0644480288028717,
-0.039095524698495865,
0.052815213799476624,
-0.021018877625465393,
0.0017680323217064142,
0.05292012169957161,
-0.013373468071222305,
-0.005794816184788942,
0.03184306621551514,
0.05837584659457207,
-0.058991387486457825,
0.004205002915114164,
-0.05951608717441559,
0.04710308089852333,
-0.06724554300308228,
0.08740582317113876,
-0.04551709443330765,
0.019947605207562447,
0.029382620006799698,
-0.019228436052799225,
-1.0514434217895538e-33,
0.046190980821847916,
-0.04813956469297409,
-0.03487025201320648,
0.04695061966776848,
-0.041898638010025024,
-0.033125244081020355,
-0.06053636595606804,
-0.07711496949195862,
0.023898044601082802,
-0.03262487053871155,
0.0027100995648652315,
0.03473176062107086,
0.027235710993409157,
-0.0734298974275589,
-0.1182718575000763,
0.03211987018585205,
0.0055675990879535675,
-0.02548292838037014,
-0.11767097562551498,
-0.057699840515851974,
-0.028750590980052948,
0.01739742048084736,
0.04936666041612625,
-0.11417388170957565,
0.030660482123494148,
0.02179841138422489,
-0.04281530901789665,
0.039403125643730164,
0.041440699249506,
-0.008902953006327152,
-0.030081041157245636,
-0.007090479135513306,
0.03853701055049896,
0.004129250533878803,
0.08317331969738007,
0.023808280006051064,
-0.006697301287204027,
-0.004253515508025885,
0.06386647373437881,
0.05286765471100807,
-0.031175393611192703,
-0.0052841100841760635,
0.00017153444059658796,
-0.0638149157166481,
0.10143592953681946,
-0.04171067848801613,
-0.02772129885852337,
0.042536184191703796,
-0.08309481292963028,
0.018318165093660355,
0.04049811139702797,
-0.08873794972896576,
0.04962249472737312,
0.039837196469306946,
0.006736602634191513,
0.07215379178524017,
-0.03140968084335327,
-0.11492878943681717,
-0.00021640726481564343,
0.10207271575927734,
0.010340061970055103,
0.03554470092058182,
0.0034110769629478455,
0.03013642318546772,
0.014534608460962772,
0.02142076939344406,
-0.16955743730068207,
-0.05527414381504059,
-0.030109019950032234,
0.10211407393217087,
0.12763896584510803,
-0.00656057009473443,
0.08939270675182343,
-0.016692141070961952,
-0.0031151387374848127,
0.008584038354456425,
-0.04719988629221916,
0.1263200342655182,
-0.08016040921211243,
0.02531176432967186,
0.008672204799950123,
-0.017660612240433693,
-0.03354979306459427,
0.1104297861456871,
0.04942590370774269,
-0.052260298281908035,
0.06995285302400589,
-0.01755274459719658,
-0.14931917190551758,
0.05727187544107437,
0.025253329426050186,
0.01663103513419628,
0.027182230725884438,
-0.04136105254292488,
-0.006446118000894785,
-2.9165316612058993e-34,
0.011761716566979885,
0.02580253966152668,
0.038292158395051956,
0.030046679079532623,
0.005161267705261707,
-0.009815228171646595,
0.08944407850503922,
-0.02073781006038189,
0.046330951154232025,
-0.04415996000170708,
0.11926048994064331,
0.05264166742563248,
-0.015108518302440643,
-0.05390561744570732,
0.019454723224043846,
0.02386225201189518,
-0.03224566951394081,
0.016147736459970474,
-0.08809302747249603,
0.0269735436886549,
0.019974874332547188,
-0.04290969297289848,
-0.018085895106196404,
0.025960084050893784,
0.030732018873095512,
-0.031057769432663918,
0.04143604263663292,
0.07585947215557098,
0.02747456356883049,
-0.053488489240407944,
-0.02357890084385872,
0.020054848864674568,
-0.04249824956059456,
-0.02537751942873001,
0.011389468796551228,
-0.030247094109654427,
0.05315606668591499,
-0.03528125584125519,
-0.04374900460243225,
-0.06700698286294937,
-0.044119637459516525,
0.07770274579524994,
-0.02355164848268032,
-0.03535151854157448,
0.04337164759635925,
0.06783677637577057,
0.08427317440509796,
0.05495401471853256,
0.028024716302752495,
-0.017536835744976997,
0.03821565955877304,
-0.07285328209400177,
0.03881176933646202,
0.059031981974840164,
-0.04369200021028519,
-0.05785822868347168,
0.026462582871317863,
0.03626079112291336,
-0.05153992399573326,
-0.030173417180776596,
-0.061300233006477356,
-0.03183048591017723,
-0.014891978353261948,
-0.004691359121352434,
0.006253380794078112,
-0.04168985038995743,
0.06039945408701897,
-0.055500295013189316,
-0.028149951249361038,
-0.03788623586297035,
0.11801907420158386,
-0.01623009890317917,
0.02410927601158619,
-0.014617228880524635,
0.009212307631969452,
-0.0329318605363369,
-0.1170830950140953,
0.012358307838439941,
0.0769079327583313,
-0.0026770178228616714,
-0.017643863335251808,
0.023635683581233025,
-0.013473954983055592,
0.04179581254720688,
0.05991695076227188,
-0.026114191859960556,
0.00453711673617363,
0.0290918480604887,
0.030971350148320198,
-0.0212874673306942,
-0.07119840383529663,
-0.03076898120343685,
-0.03397473692893982,
0.026418207213282585,
-0.03614496812224388,
-2.28138041791226e-8,
-0.006376505363732576,
-0.06068835034966469,
-0.05627277493476868,
-0.1110437735915184,
0.02364654652774334,
0.05155886709690094,
-0.057390373200178146,
0.03990531340241432,
0.0582662858068943,
0.03802802041172981,
0.09907328337430954,
0.002528388286009431,
-0.054695893079042435,
-0.06947933882474899,
-0.0061901952140033245,
0.0033182413317263126,
0.049686383455991745,
0.06174294650554657,
-0.0035729974042624235,
-0.01666252501308918,
-0.018626345321536064,
-0.007554518524557352,
0.0012195376912131906,
0.0052765896543860435,
-0.053450584411621094,
-0.003882315242663026,
0.020609479397535324,
0.02386597916483879,
-0.04327133297920227,
-0.07379461824893951,
0.020485354587435722,
-0.03955011069774628,
0.0902792364358902,
-0.02285299077630043,
-0.0032865891698747873,
0.031212106347084045,
0.08810941129922867,
0.027687279507517815,
0.06381772458553314,
0.15251566469669342,
-0.0007905258098617196,
0.0525900237262249,
-0.04015321657061577,
-0.02916169911623001,
-0.03487367928028107,
-0.024550046771764755,
0.009761638939380646,
0.011990753933787346,
-0.010234410874545574,
-0.030549630522727966,
-0.017807768657803535,
-0.028249619528651237,
-0.02842443622648716,
-0.04695745185017586,
0.022844327613711357,
-0.08839619904756546,
0.004402067977935076,
0.05052390322089195,
0.023050734773278236,
0.06224850192666054,
0.00039070783532224596,
0.028795184567570686,
-0.024106958881020546,
0.004932832438498735
] |
PMID:34232196 | Genomic profiles including mutations of HDACs were retrieved from cBioPortal webserver. | [
-0.05578113719820976,
-0.05327802523970604,
-0.0761684700846672,
-0.022877922281622887,
0.005793251097202301,
-0.047936104238033295,
-0.05186418816447258,
-0.011180349625647068,
-0.0768878161907196,
-0.030557427555322647,
0.06719391793012619,
-0.04159880056977272,
0.04805195704102516,
-0.02267090231180191,
-0.043277397751808167,
0.001508047804236412,
-0.09508926421403885,
-0.014552254229784012,
0.002006120514124632,
0.01847919449210167,
-0.049696095287799835,
0.07447590678930283,
-0.0248198714107275,
0.007240511942654848,
-0.030639834702014923,
-0.004443236161023378,
0.05743900313973427,
0.03162514418363571,
0.005477102007716894,
-0.06539882719516754,
-0.0016026869416236877,
0.021807819604873657,
0.050542186945676804,
0.00951707735657692,
0.0902264267206192,
-0.006119605153799057,
-0.026493871584534645,
-0.0060324701480567455,
0.0588441826403141,
-0.04940732195973396,
0.06781594455242157,
0.00887864176183939,
-0.013327067717909813,
0.11198119819164276,
0.01649758778512478,
-0.07947900891304016,
-0.05512107163667679,
-0.030637359246611595,
0.02701796032488346,
0.041039325296878815,
-0.05566108226776123,
-0.04348190128803253,
0.004557044245302677,
0.08636936545372009,
0.005344841163605452,
-0.035340435802936554,
-0.04365061596035957,
-0.018291492015123367,
0.11813691258430481,
0.052858393639326096,
-0.006635724566876888,
-0.01701071672141552,
0.020197216421365738,
-0.046107880771160126,
0.04072617366909981,
0.03372794762253761,
0.09103787690401077,
-0.10939820110797882,
0.06038433313369751,
-0.12032954394817352,
-0.07424337416887283,
-0.028460977599024773,
-0.037938687950372696,
0.15518152713775635,
0.06810957938432693,
0.025818536058068275,
-0.0021371571347117424,
0.010406645946204662,
-0.0047289724461734295,
-0.02582966908812523,
-0.03601134940981865,
-0.04101315885782242,
0.051552534103393555,
0.12504246830940247,
-0.02516869828104973,
0.037975408136844635,
0.05225662142038345,
-0.013080847449600697,
-0.02041027694940567,
0.024406161159276962,
0.013754301704466343,
-0.03389868140220642,
0.07486379891633987,
-0.06371379643678665,
-0.11079449206590652,
0.030020732432603836,
0.0759182944893837,
0.04411205276846886,
0.07310779392719269,
-0.0346321202814579,
0.03934928774833679,
-0.02992008440196514,
0.03151113912463188,
-0.026923852041363716,
-0.1124163419008255,
-0.04981604591012001,
0.037568215280771255,
0.0632951408624649,
-0.004262174479663372,
-0.06627465784549713,
0.00831097736954689,
0.07463624328374863,
0.005131645128130913,
-0.000902665255125612,
-0.06144222244620323,
-0.05390075594186783,
-0.005605251062661409,
-0.060452837496995926,
-0.03347969427704811,
-0.01262807659804821,
-0.007176644634455442,
-0.003085880307480693,
0.058835338801145554,
-0.04426787421107292,
0.0012573102721944451,
-0.04760570079088211,
-0.03180691599845886,
8.279173853444378e-34,
-0.01301127765327692,
0.054205603897571564,
-0.02131638303399086,
0.01911923848092556,
0.028878996148705482,
-0.12106838822364807,
0.0198383629322052,
-0.0008621187298558652,
-0.03606294468045235,
-0.05363136902451515,
-0.06176729127764702,
0.013570052571594715,
-0.010242121294140816,
-0.05073850601911545,
-0.06009599566459656,
0.02664444036781788,
-0.09006781131029129,
0.010410136543214321,
-0.020496444776654243,
0.018787972629070282,
-0.05398920550942421,
0.06173306703567505,
0.026866091415286064,
-0.11404360085725784,
0.02573971636593342,
0.014171232469379902,
-0.04374121502041817,
0.02607816644012928,
0.04230540618300438,
0.009415365755558014,
0.031421177089214325,
-0.013409382663667202,
-0.05027591809630394,
0.062122657895088196,
0.029398607090115547,
0.02775893732905388,
0.06965607404708862,
-0.0710173174738884,
-0.028919342905282974,
0.04157450422644615,
-0.04461224004626274,
0.03894714638590813,
-0.04885059595108032,
-0.026375295594334602,
0.027649089694023132,
-0.048699431121349335,
-0.03946257755160332,
-0.013645036146044731,
-0.019834784790873528,
-0.01534894946962595,
-0.07248840481042862,
-0.03152613714337349,
0.06519953906536102,
0.02080749161541462,
-0.0016357178101316094,
0.019618473947048187,
-0.016894938424229622,
-0.03873960301280022,
0.02797856740653515,
0.08077915757894516,
0.08827589452266693,
0.05785183236002922,
-0.043816301971673965,
-0.009276680648326874,
-0.03062090277671814,
-0.03988755866885185,
-0.040996551513671875,
0.010274725034832954,
0.006767428480088711,
0.0874558761715889,
0.100419782102108,
-0.04522905498743057,
0.06135253235697746,
-0.023327920585870743,
-0.022553786635398865,
-0.013354604132473469,
-0.06081122159957886,
0.07283275574445724,
-0.016223151236772537,
0.025301843881607056,
0.05360492691397667,
0.003950126469135284,
0.019871605560183525,
0.053025584667921066,
-0.0669003427028656,
-0.017768068239092827,
0.07149507850408554,
0.012071915902197361,
-0.1050250455737114,
0.019806042313575745,
0.08910726755857468,
-0.030602693557739258,
0.029860269278287888,
-0.04816267639398575,
0.0024659184273332357,
-2.113344702539595e-33,
-0.02761051245033741,
-0.0642145648598671,
0.03416157513856888,
-0.01717018149793148,
-0.03904428705573082,
-0.05954127386212349,
0.0012535175774246454,
0.058110110461711884,
0.002566385082900524,
-0.05684090778231621,
0.16270135343074799,
0.030084922909736633,
-0.037190165370702744,
-0.09405986219644547,
-0.008091356605291367,
0.07949130237102509,
-0.029516959562897682,
-0.06400441378355026,
-0.05878061056137085,
-0.007486610673367977,
0.040230534970760345,
0.031052270904183388,
-0.028713932260870934,
0.03050173632800579,
0.00944461952894926,
0.004650590941309929,
0.0742262750864029,
0.15200185775756836,
0.04572680592536926,
-0.01833338849246502,
-0.03892648220062256,
0.08009526878595352,
-0.021227525547146797,
-0.024670902639627457,
0.04444689676165581,
0.011645758524537086,
0.023278316482901573,
0.04344278573989868,
0.01607854664325714,
-0.04869375005364418,
-0.05055926740169525,
0.06998833268880844,
-0.0780763179063797,
0.03384477645158768,
0.04431550204753876,
0.0580790638923645,
-0.07799892872571945,
0.00992738176137209,
0.08173195272684097,
0.013030804693698883,
0.12228371202945709,
0.026399798691272736,
0.004325788002461195,
-0.051083218306303024,
-0.03963739797472954,
0.018562596291303635,
0.04421554133296013,
0.030176552012562752,
-0.008856131695210934,
-0.00928504578769207,
-0.05079229176044464,
-0.02718275785446167,
-0.0797688439488411,
0.05223659425973892,
0.00763931917026639,
0.008106114342808723,
-0.07858608663082123,
-0.025377927348017693,
-0.03218187019228935,
-0.043168701231479645,
0.06045933812856674,
-0.047581955790519714,
0.08305546641349792,
-0.028409816324710846,
0.009079941548407078,
-0.029868558049201965,
-0.0568850040435791,
0.028060205280780792,
0.044732190668582916,
0.06263798475265503,
0.03668035939335823,
0.05197286233305931,
0.021148065105080605,
0.0544050894677639,
0.013540240004658699,
-0.026566339656710625,
-0.030447473749518394,
-0.04650463908910751,
-0.043421413749456406,
-0.04431059956550598,
-0.058988578617572784,
-0.024832764640450478,
-0.11762706190347672,
0.05418284609913826,
0.035937048494815826,
-1.975236685325399e-8,
0.005639120936393738,
-0.05265730619430542,
-0.03865772858262062,
0.001666803378611803,
0.043785396963357925,
0.06213263049721718,
-0.09523683041334152,
0.08028917759656906,
0.07482676208019257,
0.0239524245262146,
0.04930886998772621,
0.05203760415315628,
-0.038515157997608185,
0.04107310622930527,
0.0017789185512810946,
-0.00038753970875404775,
0.016993531957268715,
0.025941787287592888,
0.010051185265183449,
-0.007765969727188349,
-0.03806636109948158,
0.03242439031600952,
0.050534989684820175,
0.0035546552389860153,
0.06562831252813339,
-0.05112038180232048,
0.02842283621430397,
-0.01085334550589323,
0.008458266034722328,
-0.10824480652809143,
-0.0276348777115345,
-0.060483887791633606,
-0.02084917388856411,
-0.0019018229795619845,
0.017870554700493813,
0.019328024238348007,
-0.10900421440601349,
-0.05302821472287178,
-0.03681984543800354,
0.09129021316766739,
0.10707783699035645,
0.003396059852093458,
-0.08684946596622467,
-0.0061941291205585,
-0.011898281052708626,
-0.06675668805837631,
-0.02012668550014496,
0.0783698707818985,
0.0526123046875,
-0.06774003803730011,
0.02691289223730564,
-0.11195655167102814,
0.04699768126010895,
-0.04988846927881241,
-0.015499243512749672,
-0.02328306809067726,
0.034502074122428894,
0.04430004581809044,
0.04653644561767578,
0.06431999057531357,
0.025297293439507484,
0.07720237225294113,
0.07965357601642609,
0.0019292631186544895
] |
PMID:34232196 | A protein-protein interaction network was constructed using STRING database. | [
-0.016471359878778458,
-0.08155155181884766,
-0.039528556168079376,
-0.04219995439052582,
-0.07200371474027634,
0.02114773727953434,
0.017620602622628212,
0.0883500725030899,
0.00853483472019434,
-0.047647152096033096,
0.022470256313681602,
0.017795952036976814,
0.0647810623049736,
0.03733489289879799,
-0.05843449383974075,
0.12143849581480026,
-0.04172335937619209,
-0.012389306910336018,
-0.010795834474265575,
-0.04920909181237221,
-0.03061479888856411,
-0.004246733151376247,
0.008869488723576069,
-0.01689666323363781,
-0.009163305163383484,
0.03323909640312195,
0.022117262706160545,
0.05856194347143173,
0.005590091459453106,
-0.012104896828532219,
0.016542263329029083,
-0.04053217172622681,
0.056104905903339386,
0.013101087883114815,
-0.035411275923252106,
0.028123486787080765,
0.014983604662120342,
-0.07279117405414581,
-0.02211887016892433,
-0.04308764636516571,
0.06303087621927261,
0.03858620673418045,
0.04076876491308212,
0.008726525120437145,
0.03258553147315979,
0.050680361688137054,
-0.12867556512355804,
0.0436038114130497,
0.06332746893167496,
0.024047760292887688,
-0.0520164892077446,
-0.04565396532416344,
-0.009096366353332996,
0.03721538186073303,
0.06700462847948074,
0.08183731138706207,
-0.08640694618225098,
0.02387418784201145,
-0.014746280387043953,
0.006874313578009605,
0.02407248318195343,
-0.026711441576480865,
0.019709793850779533,
0.013441009446978569,
0.0933690145611763,
0.01905926689505577,
0.029711628332734108,
0.08811859786510468,
0.03859749808907509,
-0.10180269926786423,
-0.04566626995801926,
0.03238498419523239,
-0.13591840863227844,
0.08228994905948639,
-0.014516006223857403,
0.09765036404132843,
-0.025397570803761482,
0.013083054684102535,
0.05027087405323982,
-0.01941373571753502,
-0.007213111501187086,
-0.004955122712999582,
0.03884829953312874,
0.022528130561113358,
-0.0005385002586990595,
-0.049026645720005035,
0.02118995413184166,
0.06167477369308472,
0.0045095887035131454,
0.04287820681929588,
0.006119702942669392,
-0.06927324831485748,
0.07412485778331757,
-0.040045809000730515,
-0.047041185200214386,
0.03287571296095848,
-0.01770043559372425,
-0.048950403928756714,
0.017361922189593315,
0.031389087438583374,
-0.07876156270503998,
-0.018382050096988678,
0.055701844394207,
-0.0614667572081089,
-0.05599650368094444,
0.031094172969460487,
-0.006125907879322767,
0.01865731179714203,
0.06639038026332855,
-0.0348961278796196,
-0.03002185747027397,
-0.018923319876194,
0.0023496311623603106,
-0.035728711634874344,
-0.016009308397769928,
0.02034692093729973,
0.002462086733430624,
-0.048438910394907,
0.04819850996136665,
0.01033317856490612,
-0.035142019391059875,
-0.014843573793768883,
-0.021000375971198082,
-0.015624050982296467,
-0.06964603811502457,
-0.0002536999818403274,
-0.13782565295696259,
-4.7092632642123404e-33,
0.031234577298164368,
-0.0034761575516313314,
0.046419013291597366,
-0.025175949558615685,
-0.007182870991528034,
-0.07290530204772949,
-0.06366714090108871,
0.012246969155967236,
0.011556882411241531,
-0.0664648711681366,
-0.09419916570186615,
0.04800025001168251,
0.08177205175161362,
-0.0388757549226284,
0.04002241790294647,
0.007422877941280603,
0.10813980549573898,
0.06515445560216904,
-0.03646126389503479,
0.015915321186184883,
-0.03561156988143921,
0.0145316356793046,
0.05113040283322334,
-0.010162296704947948,
0.06774213910102844,
0.024007514119148254,
-0.023629961535334587,
-0.01708126813173294,
0.03640175610780716,
-0.03526271507143974,
-0.05135215446352959,
-0.1012025848031044,
-0.05372477322816849,
0.03166908770799637,
0.10309308022260666,
-0.01912687160074711,
0.09738477319478989,
-0.07380244880914688,
-0.004741375334560871,
0.0011782492510974407,
-0.005405250005424023,
-0.052555717527866364,
-0.007544414140284061,
-0.0250699482858181,
0.00022510932467412204,
0.026249533519148827,
-0.010782860219478607,
0.035548027604818344,
-0.03836211934685707,
-0.012717668898403645,
0.06308072805404663,
-0.009542006067931652,
0.013342740945518017,
0.017244793474674225,
-0.03748679533600807,
0.0655541643500328,
-0.006140393670648336,
0.007862022146582603,
0.05756441131234169,
0.1363925039768219,
-0.06890369206666946,
0.020576942712068558,
-0.0025463132187724113,
0.014555343426764011,
0.07933877408504486,
0.026272745802998543,
-0.09298191964626312,
-0.0492401160299778,
0.07003745436668396,
0.10615550726652145,
-0.06989152729511261,
0.03418625146150589,
-0.02827618643641472,
-0.04154657945036888,
-0.011810585856437683,
-0.0010056992759928107,
-0.13020561635494232,
-0.0993378683924675,
-0.054940592497587204,
0.12233847379684448,
-0.023413194343447685,
-0.054759226739406586,
-0.06877487152814865,
0.017666958272457123,
-0.09444528818130493,
-0.04250086843967438,
0.06080036982893944,
-0.07639196515083313,
-0.015210116282105446,
-0.023135166615247726,
0.025321386754512787,
-0.007255280390381813,
0.0037411267403513193,
0.04932279512286186,
0.06400658935308456,
2.026888929746539e-33,
0.043168649077415466,
-0.01105477660894394,
0.029256949201226234,
-0.020556675270199776,
0.02458932250738144,
0.005611133761703968,
0.05053601786494255,
-0.030623087659478188,
0.02419215440750122,
0.032726675271987915,
0.10226123780012131,
-0.047667309641838074,
0.010330040007829666,
-0.07579001784324646,
0.061441801488399506,
0.039801158010959625,
-0.11526414752006531,
-0.00020251530804671347,
0.06297847628593445,
0.03395034372806549,
-0.026458464562892914,
0.054624032229185104,
-0.040491510182619095,
0.01831658184528351,
-0.015372546389698982,
0.015273320488631725,
0.03466661274433136,
-0.0008585770847275853,
-0.004189383704215288,
0.07296685874462128,
-0.09717521071434021,
-0.036478932946920395,
-0.0004141448880545795,
-0.01564824767410755,
-0.07684263586997986,
0.04839209467172623,
0.060892362147569656,
0.0007223339634947479,
0.08642902225255966,
-0.11131478101015091,
0.04047539085149765,
0.09605491161346436,
-0.12706007063388824,
0.029087448492646217,
0.0072131832130253315,
0.017356840893626213,
-0.11104181408882141,
0.04625639691948891,
-0.03585139662027359,
-0.01532696932554245,
0.05173411965370178,
-0.02295829728245735,
0.04884668439626694,
-0.06715211272239685,
-0.04036179557442665,
-0.009122536517679691,
-0.025856463238596916,
0.05394836142659187,
-0.015631703659892082,
-0.011152614839375019,
-0.0630413368344307,
-0.08858393877744675,
0.04920714348554611,
0.0848764032125473,
0.030346430838108063,
0.05000939592719078,
-0.016889920458197594,
-0.013862724415957928,
0.010170436464250088,
-0.09364861249923706,
0.014334323816001415,
0.05331791937351227,
0.0795740857720375,
0.1197948083281517,
0.05360157787799835,
-0.06757597625255585,
-0.09741687029600143,
0.005857634358108044,
0.02219201624393463,
0.04517615586519241,
-0.05110013112425804,
0.05958980321884155,
0.041143596172332764,
0.005295213777571917,
0.056455790996551514,
0.054398342967033386,
-0.0224271472543478,
0.09877432137727737,
0.03246624395251274,
0.06791932880878448,
-0.020966682583093643,
0.06631053239107132,
-0.057844020426273346,
0.09749441593885422,
-0.013179244473576546,
-1.68248597276488e-8,
0.017568903043866158,
-0.013330132700502872,
0.010005076415836811,
0.016437603160738945,
0.05683785304427147,
0.060185011476278305,
-0.04228900745511055,
0.03274587541818619,
-0.02237042784690857,
0.0867084413766861,
0.0323462076485157,
0.006538074929267168,
-0.10208456218242645,
-0.02648972161114216,
-0.025803033262491226,
0.007130937185138464,
0.012468651868402958,
-0.07975099235773087,
-0.03110167570412159,
0.03800750896334648,
0.03829917311668396,
0.03937660530209541,
-0.052696142345666885,
0.05715496093034744,
0.05005495622754097,
-0.054236650466918945,
-0.06434984505176544,
0.07673291116952896,
-0.034266844391822815,
-0.0076194447465240955,
0.010496212169528008,
-0.014740929007530212,
-0.03123561665415764,
-0.0803963914513588,
-0.05250938609242439,
0.02712254785001278,
0.01462822686880827,
-0.06899390369653702,
-0.013809765689074993,
0.007133114151656628,
0.011518577113747597,
0.02695559896528721,
-0.04880865290760994,
-0.037659648805856705,
0.021199332550168037,
-0.014921266585588455,
0.07222810387611389,
-0.020851073786616325,
0.01877327263355255,
-0.03269984945654869,
-0.03460428863763809,
0.006219185423105955,
-0.036147985607385635,
-0.04381391033530235,
-0.07892542332410812,
-0.0037272435147315264,
-0.06202693283557892,
-0.06086311861872673,
0.046399593353271484,
-0.05070807784795761,
0.014759923331439495,
-0.07492613792419434,
0.06976527720689774,
-0.01819036155939102
] |
PMID:34232196 | GeneMANIA was used to retrieve additional genes or proteins related to HDACs. | [
-0.054262466728687286,
-0.008769866079092026,
-0.05692625418305397,
-0.05666416510939598,
0.017673883587121964,
0.019182831048965454,
-0.038643576204776764,
0.045552246272563934,
-0.04758502542972565,
0.06396256387233734,
0.08243365585803986,
0.07788614928722382,
-0.00935905147343874,
-0.019077913835644722,
-0.031011145561933517,
0.02467559464275837,
-0.04650858789682388,
0.03775100037455559,
-0.010070361196994781,
-0.019932886585593224,
0.034804824739694595,
0.06997137516736984,
0.05234559252858162,
0.012195175513625145,
-0.08945494145154953,
0.05157838389277458,
0.05330899730324745,
0.034163396805524826,
-0.0077790794894099236,
-0.015787068754434586,
-0.0434473492205143,
-0.0033897897228598595,
0.027881475165486336,
-0.001262408564798534,
-0.024699782952666283,
0.04481564834713936,
-0.05539143830537796,
0.040365301072597504,
0.026587044820189476,
-0.058426350355148315,
0.09199807792901993,
-0.007971083745360374,
0.012795865535736084,
0.03446683660149574,
-0.0482424832880497,
-0.10511117428541183,
-0.01504420954734087,
-0.0020323714707046747,
0.11127711832523346,
0.027728918939828873,
-0.0163732897490263,
-0.012675969861447811,
0.0320470966398716,
0.006824403535574675,
-0.006281260401010513,
0.014516044408082962,
-0.016113903373479843,
-0.06657737493515015,
0.02321290783584118,
-0.011907677166163921,
-0.04984179511666298,
-0.030502138659358025,
-0.04533997178077698,
-0.06762576848268509,
0.07552669942378998,
-0.1127416267991066,
0.010601348243653774,
0.02605913206934929,
-0.009930714964866638,
-0.0076836710795760155,
-0.012284712865948677,
-0.029240556061267853,
-0.012776972725987434,
0.11604438722133636,
0.02082042023539543,
0.011099954135715961,
0.025198739022016525,
-0.015493018552660942,
0.006743593141436577,
-0.031458042562007904,
0.008202958852052689,
0.05628788098692894,
0.06359520554542542,
0.08721134811639786,
-0.010987701825797558,
0.04795592650771141,
0.007036223541945219,
0.0351402685046196,
0.04466068372130394,
0.003985774703323841,
0.026329170912504196,
-0.12414728850126266,
0.07776050269603729,
-0.0301715899258852,
-0.08854816108942032,
-0.016183577477931976,
0.05097968876361847,
0.021995186805725098,
0.09609702229499817,
-0.052127644419670105,
0.06436970084905624,
-0.0681159645318985,
-0.04892897605895996,
-0.03391766548156738,
-0.048309020698070526,
0.03244074806571007,
-0.053852006793022156,
0.07328826934099197,
-0.0036500999704003334,
-0.01768464408814907,
-0.058660250157117844,
0.06590128690004349,
0.027018899098038673,
0.02749144285917282,
-0.04215966537594795,
-0.00037165230605751276,
0.023918595165014267,
-0.04946361854672432,
-0.03815723583102226,
-0.060385048389434814,
-0.02811686135828495,
-0.06133639067411423,
0.08926093578338623,
-0.04938957467675209,
0.03629572317004204,
0.007794622797518969,
-0.10457522422075272,
-3.621243692848478e-33,
-0.024591175839304924,
-0.020351115614175797,
-0.008965699002146721,
0.07584921270608902,
-0.042181000113487244,
-0.01278754323720932,
-0.0006495881825685501,
0.019368883222341537,
-0.04379266873002052,
-0.0801948830485344,
-0.09707393497228622,
0.017554091289639473,
0.019089264795184135,
-0.004428798332810402,
-0.07521075755357742,
0.028920436277985573,
-0.02533714845776558,
0.00013976721675135195,
-0.011062678880989552,
0.05380195006728172,
-0.09675725549459457,
0.07530713826417923,
0.0226399227976799,
-0.048100344836711884,
0.03085828758776188,
-0.013702718541026115,
-0.004597371444106102,
-0.06328132003545761,
-0.0015644755912944674,
0.005544866435229778,
-0.03350372239947319,
-0.02004992961883545,
-0.058792781084775925,
0.05077757313847542,
0.0822877511382103,
0.11906398087739944,
0.08560986816883087,
-0.07710158079862595,
-0.0274642426520586,
-0.03822891041636467,
-0.05076751857995987,
0.028960570693016052,
-0.021963438019156456,
-0.07050768285989761,
0.033649396151304245,
-0.03367212042212486,
-0.020029617473483086,
0.006754702888429165,
-0.08922846615314484,
0.0562758706510067,
0.06015228480100632,
0.017330290749669075,
0.09423454850912094,
-0.036060597747564316,
-0.0849752426147461,
0.05006144940853119,
-0.012153808027505875,
0.014509325847029686,
0.06114582344889641,
0.09423234313726425,
-0.000597997335717082,
0.0642910823225975,
-0.023745492100715637,
0.06472837924957275,
0.020219724625349045,
0.01062069833278656,
-0.02006775513291359,
-0.03190106153488159,
0.040841635316610336,
0.06677139550447464,
0.06498364359140396,
-0.018326539546251297,
0.014475037343800068,
-0.0340944267809391,
0.00694902241230011,
0.008414722047746181,
-0.05568907782435417,
0.034089796245098114,
-0.03073018603026867,
0.014519094489514828,
0.03547276556491852,
-0.04068661481142044,
0.028570281341671944,
0.05283728614449501,
-0.04301045089960098,
0.0990835502743721,
0.019913068041205406,
-0.03225388750433922,
-0.08629779517650604,
-0.02920527756214142,
0.09149089455604553,
-0.079676553606987,
-0.02954154834151268,
-0.04461924359202385,
-0.042656928300857544,
7.752269530947827e-34,
0.023808350786566734,
-0.03650888428092003,
0.003389068879187107,
-0.03240874037146568,
0.004237039480358362,
0.003839444601908326,
-0.002481456845998764,
0.01737329363822937,
-0.07260075956583023,
-0.041137322783470154,
0.1355242282152176,
-0.041211504489183426,
0.005685943644493818,
-0.08406506478786469,
0.05052283778786659,
0.06000322848558426,
-0.08735961467027664,
-0.08788270503282547,
-0.020821189507842064,
0.011439565569162369,
-0.053586337715387344,
0.03308751434087753,
0.02297043614089489,
0.05796300992369652,
-0.05664430931210518,
-0.0316324420273304,
-0.022481637075543404,
0.1562921404838562,
-0.02268468216061592,
-0.010509535670280457,
-0.031737297773361206,
-0.008225798606872559,
-0.024671494960784912,
-0.06686022132635117,
0.050280045717954636,
0.022564170882105827,
0.05177238956093788,
0.030538219958543777,
-0.0004775786946993321,
-0.008034794591367245,
-0.05843271687626839,
0.08571777492761612,
-0.02031809091567993,
0.03996830806136131,
0.01265054289251566,
0.08795471489429474,
-0.051305826753377914,
0.049477800726890564,
0.031810253858566284,
-0.027956297621130943,
0.10236910730600357,
-0.0282389298081398,
0.05716059356927872,
0.003845528233796358,
-0.009941492229700089,
-0.020482011139392853,
0.025343209505081177,
0.02534491755068302,
0.02210213616490364,
0.041749581694602966,
-0.035646334290504456,
-0.05026969313621521,
-0.10583489388227463,
0.05106791853904724,
0.04592441767454147,
-0.0365852527320385,
-0.05331756919622421,
-0.05157313123345375,
-0.0686248391866684,
-0.006613221950829029,
0.06891253590583801,
-0.007690632250159979,
0.09496373683214188,
0.04563681036233902,
0.04188332334160805,
0.015516932122409344,
-0.10593520104885101,
0.012056466192007065,
0.03398338332772255,
0.07360437512397766,
-0.027293778955936432,
-0.03503317013382912,
0.0813232809305191,
0.0544649139046669,
0.050888948142528534,
-0.022544795647263527,
0.010877855122089386,
-0.001881629228591919,
-0.08492763340473175,
-0.010267673060297966,
0.03166785091161728,
-0.056286461651325226,
-0.050955723971128464,
0.07984898239374161,
-0.01200800109654665,
-1.816692218881144e-8,
0.09751025587320328,
-0.08984385430812836,
0.009153587743639946,
-0.0948847159743309,
-0.004032527096569538,
-0.022081108763813972,
-0.09631812572479248,
0.12574312090873718,
0.065757155418396,
0.019056666642427444,
-0.02427254058420658,
0.05087871477007866,
-0.03222861513495445,
0.07107793539762497,
0.004985892679542303,
0.013592259027063847,
0.057296838611364365,
0.04996290057897568,
-0.02937769889831543,
-0.03278929367661476,
-0.048674553632736206,
0.011312155053019524,
-0.05153830349445343,
0.07345369458198547,
0.032381560653448105,
0.016534021124243736,
0.01416618563234806,
-0.022493841126561165,
0.07128077745437622,
-0.12631067633628845,
-0.09825756400823593,
-0.045663367956876755,
-0.0017063936684280634,
-0.016769587993621826,
-0.04003738984465599,
0.04576697573065758,
0.005789124872535467,
-0.0799812451004982,
0.04474760964512825,
0.038699280470609665,
0.07297685742378235,
0.030520960688591003,
-0.05295984819531441,
-0.0024648078251630068,
0.019844787195324898,
-0.028186174109578133,
0.019734632223844528,
0.05415427312254906,
0.005004114005714655,
-0.09940662235021591,
-0.017670001834630966,
0.005546304862946272,
-0.0014558263355866075,
-0.09120083600282669,
-0.06782232969999313,
-0.07992297410964966,
-0.02344941534101963,
-0.02291368506848812,
0.02154976688325405,
-0.028743404895067215,
0.0380951389670372,
0.10899889469146729,
0.05855702608823776,
0.02445034310221672
] |
PMID:34232196 | R software was used for functional enrichment analyses.Analysis of mRNA levels of HDAC1/2/4/8/9 showed that they were upregulated in GC tissues, whereas HDAC6/10 was downregulated in GC tissues. | [
-0.009364685043692589,
-0.0939205214381218,
-0.04524980112910271,
-0.015914026647806168,
-0.015273133292794228,
0.009322723373770714,
-0.017234964296221733,
0.06784729659557343,
-0.09231463819742203,
0.0033300258219242096,
-0.027906062081456184,
0.028790052980184555,
-0.04704596474766731,
0.035860393196344376,
-0.005470640491694212,
-0.005025957711040974,
-0.06665783375501633,
-0.024146830663084984,
-0.07834387570619583,
-0.024139631539583206,
-0.025313690304756165,
0.06742580980062485,
0.0497620515525341,
0.04564233869314194,
0.05976147949695587,
-0.06959361582994461,
0.029331060126423836,
0.00833088904619217,
-0.019869331270456314,
0.007599169854074717,
0.0072518279775977135,
-0.04632066562771797,
0.11508411169052124,
0.045224811881780624,
0.004784221760928631,
0.010357581079006195,
-0.09001363813877106,
-0.028454231098294258,
0.01578456163406372,
-0.016990208998322487,
0.010689068585634232,
-0.005067313089966774,
0.008079731836915016,
-0.001012124354019761,
0.042207490652799606,
-0.10358487069606781,
-0.053729720413684845,
-0.008534783497452736,
0.04951119422912598,
0.09683806449174881,
0.03542548418045044,
-0.004614232107996941,
-0.05055505409836769,
0.02656881883740425,
0.042191099375486374,
0.03115648403763771,
-0.041555870324373245,
-0.05440542474389076,
0.03478804603219032,
0.012460648082196712,
-0.10003681480884552,
-0.05835618078708649,
0.0025071853306144476,
-0.027714183554053307,
0.09826210141181946,
-0.026371680200099945,
0.06248703598976135,
-0.012859471142292023,
-0.016025561839342117,
-0.029353491961956024,
-0.019760271534323692,
-0.055290576070547104,
-0.007608453743159771,
0.017553891986608505,
0.018512975424528122,
0.018266471102833748,
-0.07382947206497192,
-0.02915188856422901,
0.05468512699007988,
-0.03618333116173744,
0.05319560691714287,
0.020412232726812363,
0.04403417930006981,
0.09293240308761597,
-0.04155208170413971,
0.06712289899587631,
0.012665916234254837,
0.048621173948049545,
-0.07404425740242004,
0.0711381807923317,
0.12192943692207336,
-0.007918750867247581,
0.08008047938346863,
-0.04504143446683884,
-0.015529492869973183,
-0.025504762306809425,
0.045371271669864655,
0.02077677473425865,
0.0676165223121643,
-0.07149051129817963,
0.040588222444057465,
-0.0034710492473095655,
-0.05317007377743721,
-0.06002097204327583,
-0.06606794893741608,
0.03799258545041084,
0.018652528524398804,
0.08289113640785217,
-0.03432583808898926,
0.01364243682473898,
-0.006834338419139385,
0.0152909429743886,
-0.03178773820400238,
-0.006416631396859884,
-0.01829061657190323,
-0.006944436579942703,
0.053099390119314194,
-0.08710996061563492,
-0.06997331976890564,
-0.035076484084129333,
0.016119183972477913,
-0.11084051430225372,
0.11654137820005417,
-0.039407625794410706,
0.025625236332416534,
-0.028304200619459152,
-0.035134099423885345,
9.772061780893261e-34,
0.02769208885729313,
-0.07452130317687988,
-0.045664336532354355,
0.03998759761452675,
-0.018929757177829742,
-0.010566432029008865,
-0.08974821865558624,
-0.02591327577829361,
-0.014357914216816425,
-0.050790172070264816,
-0.05720507353544235,
0.056903474032878876,
0.0050687710754573345,
-0.02385934814810753,
-0.05488383397459984,
0.034110620617866516,
-0.015317566692829132,
0.022620979696512222,
-0.033284131437540054,
-0.065529003739357,
-0.005961738061159849,
0.03503074124455452,
0.0803193673491478,
-0.07537996023893356,
0.014943226240575314,
0.005664291325956583,
-0.07031357288360596,
0.04870282858610153,
-0.018682993948459625,
-0.026925330981612206,
-0.07380710542201996,
-0.037865716964006424,
0.03638802841305733,
0.035893041640520096,
0.07877548784017563,
0.03379702568054199,
0.022476648911833763,
-0.021635377779603004,
0.028329530730843544,
0.056617382913827896,
0.0660882368683815,
-0.00464110029861331,
0.017805619165301323,
-0.06507778912782669,
0.11522319912910461,
-0.008641081862151623,
-0.03498000651597977,
0.041573308408260345,
-0.07956552505493164,
0.08313445001840591,
0.02689310908317566,
-0.040277156978845596,
0.07871674001216888,
0.0014291186816990376,
-0.004668896552175283,
0.04433157294988632,
-0.04666849970817566,
-0.027873365208506584,
0.05438949167728424,
0.13358701765537262,
0.027741486206650734,
0.056620024144649506,
0.022776946425437927,
0.04727732017636299,
0.014870240353047848,
-0.022084878757596016,
-0.1518702507019043,
-0.058867957442998886,
-0.03625932335853577,
0.142809197306633,
0.10591311752796173,
-0.06789582967758179,
0.08555308729410172,
0.012147283181548119,
0.022346405312418938,
0.015531949698925018,
-0.05330311879515648,
0.0880587175488472,
-0.04984632506966591,
0.015345307067036629,
-0.004772630054503679,
-0.02836015075445175,
-0.05428420007228851,
0.06211255118250847,
-0.006732664071023464,
-0.0003537928860168904,
0.049278922379016876,
-0.07148443907499313,
-0.07313423603773117,
0.025366388261318207,
0.07065288722515106,
-0.033097587525844574,
0.003788612550124526,
-0.09611494839191437,
0.03252293914556503,
-1.9782794832751525e-33,
0.014791496098041534,
-0.015643352642655373,
-0.007438879460096359,
-0.023374835029244423,
-0.008275712840259075,
0.03118315525352955,
0.08153591305017471,
-0.09065017104148865,
0.011131217703223228,
0.021051663905382156,
0.10481563210487366,
0.03366250917315483,
0.013980120420455933,
-0.0737832561135292,
0.01246323436498642,
-0.026743881404399872,
-0.029122453182935715,
0.015621968545019627,
-0.07347965240478516,
0.045189980417490005,
0.01601024903357029,
-0.053404971957206726,
0.01757816970348358,
0.039949074387550354,
0.029708055779337883,
-0.004831796977669001,
0.02979639731347561,
0.07471691817045212,
0.056332480162382126,
-0.0153473149985075,
-0.059168096631765366,
0.08267686516046524,
-0.06854976713657379,
-0.033861517906188965,
0.026994062587618828,
-0.05555424839258194,
0.05800102651119232,
-0.014292552135884762,
-0.03012927621603012,
-0.04899726063013077,
-0.047428615391254425,
0.07004831731319427,
-0.0617109052836895,
-0.023737972602248192,
0.023601332679390907,
-0.009008771739900112,
-0.022446103394031525,
0.019846860319375992,
-0.027975942939519882,
-0.008343754336237907,
0.04738445207476616,
-0.057673558592796326,
0.05478840321302414,
0.03207311034202576,
0.010799719020724297,
-0.04785923287272453,
0.07900721579790115,
0.04364440590143204,
-0.024140235036611557,
0.015487991273403168,
-0.10007314383983612,
0.008915893733501434,
-0.052985284477472305,
-0.02198200672864914,
0.028582235798239708,
-0.03769565373659134,
0.053713608533144,
-0.045701853930950165,
-0.04991789162158966,
-0.02207523211836815,
0.07824020832777023,
-0.0457480363547802,
0.07985720783472061,
-0.01233484037220478,
-0.00890900008380413,
-0.006647284608334303,
-0.11129862815141678,
-0.010876383632421494,
0.061051394790410995,
0.0035426404792815447,
-0.013736293651163578,
-0.022621458396315575,
-0.021141700446605682,
0.08053983747959137,
-0.0016764863394200802,
0.0030258754268288612,
-0.03525957092642784,
0.045881569385528564,
0.030472269281744957,
0.004240134265273809,
-0.03134844824671745,
-0.03300604224205017,
-0.06856218725442886,
0.01746409200131893,
-0.03296166658401489,
-3.136429072014835e-8,
0.0017171903746202588,
-0.10650256276130676,
-0.03745245188474655,
-0.07359867542982101,
0.03858218714594841,
-0.00701686879619956,
-0.0936942920088768,
0.06282181292772293,
0.02929542027413845,
0.04702393338084221,
0.08573654294013977,
-0.007992037571966648,
-0.07792413234710693,
-0.05345518887042999,
-0.0010331810917705297,
0.00936801452189684,
0.015575782395899296,
0.03965585678815842,
-0.015014615841209888,
-0.04381132870912552,
-0.03468159958720207,
0.02370316907763481,
-0.006722196005284786,
0.030886348336935043,
-0.03578846529126167,
-0.05353216826915741,
-0.014231299981474876,
0.0834963396191597,
0.006799962837249041,
-0.12378589063882828,
0.09297291189432144,
-0.03487095981836319,
0.04973502457141876,
-0.08780202269554138,
0.021290596574544907,
0.022649558261036873,
0.11100170016288757,
0.010127674788236618,
-0.03784264996647835,
0.175608292222023,
-0.0035495224874466658,
0.02001432701945305,
-0.037068843841552734,
-0.036787014454603195,
-0.06978272646665573,
-0.019035901874303818,
-0.024040911346673965,
0.05184224992990494,
0.030751174315810204,
-0.050938721746206284,
0.006175672169774771,
-0.02345450408756733,
-0.06633458286523819,
-0.0660250261425972,
0.0007743591559119523,
-0.06593739986419678,
0.005634710192680359,
0.044067833572626114,
0.024670280516147614,
0.06119628995656967,
0.018756220117211342,
0.10640376061201096,
0.0326235331594944,
-0.04952695593237877
] |
PMID:34232196 | Aberrant expression of HDAC1/3/4/5/6/7/8/10/11 was all correlated with prognosis in GC. | [
-0.11432148516178131,
-0.10085619986057281,
0.0064254458993673325,
-0.010523787699639797,
0.025292253121733665,
-0.0035343077033758163,
-0.013760131783783436,
0.06657077372074127,
-0.027892280369997025,
0.033190175890922546,
-0.0002778322377707809,
0.047065217047929764,
-0.02144363336265087,
-0.023693576455116272,
-0.08389289677143097,
-0.01771732047200203,
-0.09496738761663437,
-0.021617842838168144,
-0.0574600026011467,
0.0005102073773741722,
-0.04890308901667595,
0.0566801093518734,
0.029438793659210205,
0.09052838385105133,
0.03150906413793564,
-0.06929968297481537,
0.06566409021615982,
0.030960451811552048,
-0.05692625045776367,
0.011886884458363056,
-0.024328675121068954,
-0.02350659668445587,
0.032854095101356506,
0.021543174982070923,
0.059967394918203354,
0.036065101623535156,
-0.060714006423950195,
-0.04825618863105774,
-0.00562524888664484,
-0.06378059834241867,
0.05690833181142807,
-0.05254704877734184,
-0.03716306388378143,
0.00607843603938818,
0.008961036801338196,
-0.05185922980308533,
-0.021530887112021446,
0.003442236687988043,
0.016482846811413765,
0.09865744411945343,
0.024912532418966293,
-0.014050113968551159,
-0.05677990987896919,
0.0036139311268925667,
0.06339334696531296,
-0.004781326279044151,
-0.08178618550300598,
-0.06400864571332932,
0.12674371898174286,
0.015312131494283676,
-0.0661427453160286,
-0.04442970082163811,
0.013044754043221474,
-0.016118619590997696,
0.06859445571899414,
0.011809523217380047,
0.07270652055740356,
-0.0613216832280159,
-0.05833236128091812,
0.02474280074238777,
0.01814792864024639,
-0.04880642890930176,
0.006834383122622967,
0.05158383771777153,
0.01666967198252678,
0.04288685694336891,
-0.045670051127672195,
-0.06611819565296173,
0.03576988726854324,
-0.014537601731717587,
0.009618068113923073,
0.05288301780819893,
0.06481922417879105,
0.08949314802885056,
-0.012365070171654224,
0.0034638673532754183,
0.027453316375613213,
-0.012666000984609127,
-0.022321386262774467,
-0.012735485099256039,
0.07060561329126358,
-0.030236246064305305,
0.05393306538462639,
-0.06722082942724228,
-0.0016294644447043538,
-0.0010735756950452924,
0.0415370799601078,
0.014309232123196125,
0.07405488938093185,
-0.05347713083028793,
0.015247013419866562,
0.004761676304042339,
-0.0260258037596941,
-0.036549437791109085,
-0.04686232656240463,
0.023093419149518013,
-0.014735215343534946,
0.06721323728561401,
-0.0706799328327179,
-0.025148212909698486,
-0.022487308830022812,
-0.00007979822112247348,
0.012812013737857342,
-0.005174728576093912,
-0.05590289458632469,
0.02103588730096817,
0.05516153201460838,
-0.0663255974650383,
-0.06618543714284897,
-0.019625600427389145,
0.0008402534876950085,
-0.0973789319396019,
0.09354377537965775,
-0.014623154886066914,
0.012320651672780514,
0.01782427355647087,
-0.015583554282784462,
-2.052291730009793e-33,
0.0698322206735611,
-0.08724059909582138,
-0.023495083674788475,
0.05672208219766617,
0.00529193039983511,
0.003691805526614189,
-0.047809310257434845,
-0.05027727037668228,
0.04089147970080376,
-0.006964713800698519,
0.011357246898114681,
0.05044756829738617,
0.06692696362733841,
-0.09242338687181473,
-0.17017967998981476,
0.06088453531265259,
0.026977766305208206,
0.006052234210073948,
-0.10306417942047119,
-0.04692307114601135,
-0.06472168862819672,
0.0824461579322815,
0.0569356270134449,
-0.12294474244117737,
-0.005383414216339588,
0.004992482252418995,
-0.050417810678482056,
0.09486997127532959,
0.09092932194471359,
-0.0091316569596529,
-0.037936385720968246,
0.0059544919058680534,
0.053781408816576004,
-0.017085080966353416,
0.029584985226392746,
0.04380982741713524,
0.02746606431901455,
-0.04013754799962044,
0.11589797586202621,
0.051961202174425125,
-0.014722464606165886,
0.018611812964081764,
-0.02642834186553955,
-0.09011287242174149,
0.07530950009822845,
-0.07792320102453232,
0.007789663039147854,
0.01949995942413807,
-0.12574952840805054,
0.047015924006700516,
-0.006734134629368782,
-0.03657408058643341,
0.04736066982150078,
0.020716343075037003,
-0.016138620674610138,
0.01788422465324402,
-0.03907643258571625,
-0.06233583018183708,
0.027383361011743546,
0.09849654883146286,
0.0834861770272255,
0.06070033088326454,
-0.029503995552659035,
0.050938621163368225,
-0.02602921985089779,
-0.02018161490559578,
-0.05456378310918808,
0.0008760060300119221,
-0.04026123136281967,
0.06961780786514282,
0.13437630236148834,
-0.05247456952929497,
0.05027290806174278,
0.004325438290834427,
0.05266941338777542,
-0.019611060619354248,
-0.022009065374732018,
0.07488467544317245,
-0.08635573834180832,
0.005283439066261053,
-0.03292516618967056,
-0.012128226459026337,
0.0037835955154150724,
0.10988220572471619,
-0.06725797057151794,
-0.017894331365823746,
0.03386308252811432,
-0.04182573780417442,
-0.17163515090942383,
0.05028632655739784,
0.07634206116199493,
-0.01921553909778595,
0.03569826856255531,
-0.005878743249922991,
0.03811369463801384,
-4.100172509303622e-34,
-0.01455143466591835,
-0.005765814334154129,
0.05788001790642738,
-0.1045953705906868,
-0.0002532654907554388,
0.002216142136603594,
0.058471713215112686,
-0.040230244398117065,
-0.007471079472452402,
-0.022011393681168556,
0.14529696106910706,
0.038406264036893845,
-0.031524013727903366,
-0.07409637421369553,
-0.029928818345069885,
0.0330173633992672,
-0.033039454370737076,
0.014324446208775043,
-0.07383445650339127,
0.022641798481345177,
0.09299981594085693,
-0.015167353674769402,
-0.0034627027343958616,
0.04809963330626488,
0.0010529401479288936,
0.020234104245901108,
0.05340996012091637,
0.10746704787015915,
0.04423850029706955,
0.024676265195012093,
-0.07820586860179901,
0.07352396100759506,
-0.011160199530422688,
-0.012267465703189373,
0.03212892636656761,
-0.034913018345832825,
0.011035225354135036,
-0.04381747171282768,
-0.055070001631975174,
-0.07128863781690598,
-0.01985781639814377,
0.033330272883176804,
0.006181634496897459,
-0.015531790442764759,
0.02564600110054016,
0.050566162914037704,
0.08497413247823715,
0.08238823711872101,
0.06563472002744675,
-0.007717708125710487,
0.005727445241063833,
-0.033653851598501205,
-0.019712403416633606,
0.04851742833852768,
-0.05348467081785202,
0.039735909551382065,
0.03869602829217911,
0.042707089334726334,
-0.08000240474939346,
0.01398793701082468,
-0.052768200635910034,
0.03018314205110073,
-0.012866867706179619,
-0.009940308518707752,
0.07690658420324326,
-0.009803913533687592,
0.06164786219596863,
-0.04782583937048912,
0.05694657564163208,
-0.009085592813789845,
0.05740102007985115,
-0.039349254220724106,
-0.030884629115462303,
-0.036886245012283325,
-0.018657511100172997,
-0.009401923045516014,
-0.08742355555295944,
0.000052783583669224754,
0.08488895744085312,
0.035876285284757614,
-0.007960373535752296,
0.024501439183950424,
-0.004920178093016148,
0.03447442874312401,
-0.010731943883001804,
-0.01908666267991066,
0.03066723421216011,
-0.0018064776668325067,
0.022898005321621895,
-0.019439823925495148,
-0.03462250530719757,
-0.043142467737197876,
-0.06838055700063705,
-0.0003937949950341135,
-0.0904925987124443,
-2.5866903285987064e-8,
0.02948877215385437,
-0.07947909832000732,
-0.012931223958730698,
-0.09173830598592758,
0.0027547397185117006,
-0.028175504878163338,
-0.06859821826219559,
0.06559377908706665,
0.07636437565088272,
0.07099597901105881,
0.05544518306851387,
0.05110769346356392,
-0.0303586907684803,
-0.11629614979028702,
-0.030849143862724304,
-0.016713693737983704,
-0.04536989703774452,
0.053668420761823654,
-0.030189933255314827,
-0.034335944801568985,
-0.042874760925769806,
-0.030158400535583496,
0.031467363238334656,
-0.013051951304078102,
-0.033880747854709625,
-0.021165363490581512,
-0.016476137563586235,
0.05700577050447464,
-0.05728359520435333,
-0.07336725294589996,
0.03928285092115402,
-0.05853940173983574,
0.057216789573431015,
-0.0496152862906456,
0.017582742497324944,
0.06429142504930496,
0.07540933042764664,
-0.021212462335824966,
0.014263298362493515,
0.10102935880422592,
0.0057002645917236805,
0.05763090029358864,
-0.029742449522018433,
0.0019414821872487664,
-0.05333109200000763,
-0.04537235200405121,
-0.015759628266096115,
-0.004701234400272369,
0.005157273728400469,
-0.033659014850854874,
-0.0023741787299513817,
-0.011380077339708805,
-0.027396857738494873,
-0.0648224726319313,
-0.03417535498738289,
-0.0646221861243248,
0.0008433244656771421,
0.0593915618956089,
0.0038043013773858547,
0.08314714580774307,
0.005885545630007982,
0.054535724222660065,
-0.011713763698935509,
-0.0021283836103975773
] |
PMID:34232196 | In addition, expression levels of HDACs were correlated with different Lauren classifications, and clinical stages, lymph node status, treatment, and human epidermal growth factor receptor 2 status in GC.The findings of this study showed that HDAC members are potential biomarkers for diagnosis or prognosis of gastric cancer. | [
0.025459889322519302,
-0.09016448259353638,
-0.05652397871017456,
-0.014580748043954372,
0.049045562744140625,
0.0028758107218891382,
0.04309912770986557,
0.012281977571547031,
-0.049204710870981216,
-0.024881044402718544,
-0.002715549897402525,
-0.03498184680938721,
0.007735381368547678,
-0.02195839397609234,
0.025704825296998024,
0.022937465459108353,
-0.08690792322158813,
-0.021674981340765953,
-0.057396408170461655,
-0.0554313063621521,
-0.016570575535297394,
0.00966409407556057,
0.08099860697984695,
0.12223254889249802,
-0.003451230237260461,
-0.0820586159825325,
0.0608995147049427,
0.015574177727103233,
-0.04507443681359291,
0.04596852511167526,
-0.029121462255716324,
-0.040198035538196564,
0.0602041631937027,
0.04360811039805412,
0.03050564043223858,
-0.07872097194194794,
-0.005233868025243282,
0.019746480509638786,
-0.047241706401109695,
-0.01803956925868988,
0.05757542699575424,
-0.07250981032848358,
-0.02977832406759262,
0.00841980054974556,
0.062415122985839844,
-0.08428686857223511,
-0.011599992401897907,
0.010362029075622559,
-0.05704791843891144,
0.14264178276062012,
0.024439750239253044,
-0.009838809259235859,
-0.02234886959195137,
0.021531257778406143,
0.032398514449596405,
0.00892662350088358,
-0.10406569391489029,
-0.037862926721572876,
0.0640001967549324,
-0.053414806723594666,
-0.028071964159607887,
-0.04791659861803055,
0.03347507119178772,
-0.009618368931114674,
0.06958424299955368,
-0.016747022047638893,
0.04859292507171631,
-0.09330499172210693,
-0.03875894844532013,
-0.059820033609867096,
-0.027215326204895973,
-0.0834878608584404,
0.009745661169290543,
0.15176355838775635,
0.072317935526371,
-0.06649700552225113,
-0.0032907428685575724,
-0.006537646986544132,
0.00008242136391345412,
0.017299342900514603,
0.03335515409708023,
0.03995487466454506,
-0.00543746305629611,
0.1025557592511177,
-0.07244990766048431,
0.06864972412586212,
-0.000517048581968993,
0.005508474539965391,
-0.05239120498299599,
-0.012795028276741505,
0.06677740812301636,
-0.03694546967744827,
0.026570269837975502,
-0.024233503267169,
-0.05266185849905014,
-0.07817492634057999,
-0.025471197441220284,
-0.01666302978992462,
0.057724013924598694,
-0.05788601562380791,
-0.05069446191191673,
-0.0416475385427475,
-0.046075038611888885,
-0.012265532277524471,
-0.07851098477840424,
0.014726757071912289,
0.0005507185123860836,
0.06719457358121872,
-0.04484720528125763,
-0.03456956520676613,
0.05640881508588791,
0.03820819407701492,
0.02345157414674759,
-0.023465795442461967,
-0.04813176020979881,
0.030648864805698395,
0.0011836884077638388,
-0.0863141193985939,
-0.07281462848186493,
-0.07324614375829697,
-0.04260902851819992,
-0.06087217852473259,
0.09000266343355179,
-0.0514666810631752,
0.02282712794840336,
0.026662226766347885,
-0.04272669926285744,
2.677564542190023e-33,
0.023730073124170303,
-0.00047133577754721045,
0.018785331398248672,
0.01673995889723301,
0.009989378973841667,
0.004217490088194609,
0.012229484505951405,
-0.08678453415632248,
-0.02513698861002922,
-0.025512095540761948,
0.0011761581990867853,
0.04189304634928703,
0.036735985428094864,
-0.0014477395452558994,
-0.07410524040460587,
0.053069230169057846,
0.029832473024725914,
-0.014896287582814693,
-0.09903319925069809,
-0.02630593627691269,
-0.050727494060993195,
0.06437581032514572,
0.016392389312386513,
-0.14800825715065002,
0.010233104228973389,
0.004451854154467583,
-0.05747678875923157,
0.07327458262443542,
0.037473101168870926,
0.006344221532344818,
-0.019473621621727943,
0.004645482636988163,
0.10450544953346252,
0.026254579424858093,
0.019537832587957382,
-0.008211464621126652,
0.001494780764915049,
-0.00791504792869091,
0.1329568326473236,
0.012554868124425411,
0.03647784888744354,
0.023284366354346275,
-0.014535456895828247,
-0.04536335542798042,
0.0033852411434054375,
-0.06844650954008102,
0.007819889113307,
0.06450062990188599,
-0.05926220864057541,
0.04786286875605583,
0.016709843650460243,
-0.05239216983318329,
0.057474177330732346,
0.05055895820260048,
0.029869118705391884,
0.05516383796930313,
-0.062236882746219635,
-0.03383105620741844,
0.01567375846207142,
0.08213846385478973,
-0.020070064812898636,
0.08126077800989151,
-0.013468852266669273,
0.06370758265256882,
-0.015390977263450623,
0.007715709041804075,
-0.07860738039016724,
-0.0464041493833065,
0.0051751937717199326,
0.02771025337278843,
0.07000147551298141,
0.018521711230278015,
0.0744488462805748,
-0.0065474375151097775,
0.026474809274077415,
-0.0847238153219223,
-0.042237669229507446,
0.12821440398693085,
-0.05195435509085655,
0.0654626190662384,
0.01724587380886078,
-0.06627240031957626,
0.06358339637517929,
0.13008244335651398,
-0.0589994415640831,
-0.039820607751607895,
-0.015751037746667862,
-0.054782915860414505,
-0.0642162412405014,
0.05454740673303604,
-0.023871073499321938,
0.017305590212345123,
0.06187192350625992,
0.008295535109937191,
0.026925120502710342,
-3.483004455165823e-33,
0.0019936917815357447,
0.03179190680384636,
0.007821859791874886,
-0.010373475030064583,
0.04418184235692024,
-0.03143869712948799,
0.03078245185315609,
-0.07718589156866074,
0.006773758213967085,
-0.01709916815161705,
0.17989273369312286,
0.08096670359373093,
-0.029277147725224495,
-0.0896366611123085,
0.06046188250184059,
0.030675379559397697,
0.028749199584126472,
-0.004433877766132355,
-0.04928126558661461,
-0.022827135398983955,
-0.016172319650650024,
-0.03919178992509842,
-0.047924477607011795,
-0.012763000093400478,
-0.0639725774526596,
-0.0034961430355906487,
0.09221593290567398,
0.08092990517616272,
0.026769164949655533,
-0.04163959622383118,
-0.02629164233803749,
0.043823886662721634,
-0.0570463091135025,
-0.05104784294962883,
0.06718485802412033,
-0.13815923035144806,
0.012700076214969158,
-0.07893802225589752,
-0.03913060948252678,
-0.026577116921544075,
-0.06773895770311356,
0.017589934170246124,
-0.011708050034940243,
-0.024192387238144875,
0.035799384117126465,
0.05814623832702637,
0.11477938294410706,
-0.01516475435346365,
0.0405585952103138,
-0.018862709403038025,
0.030197614803910255,
-0.028773993253707886,
0.03919338807463646,
0.03811781108379364,
0.022599568590521812,
0.05039212852716446,
-0.0036280842032283545,
0.022413361817598343,
0.02079647220671177,
-0.01139003410935402,
-0.02205946110188961,
-0.017133738845586777,
0.043470099568367004,
0.05237210914492607,
0.009833474643528461,
-0.02986772172152996,
0.005432380363345146,
-0.10498595237731934,
0.03320430591702461,
0.017261065542697906,
0.027318762615323067,
-0.05517028272151947,
0.010885684750974178,
0.04412782937288284,
-0.09398292005062103,
-0.006785130128264427,
-0.07893922179937363,
0.009696823544800282,
0.05305805429816246,
0.03797796741127968,
-0.04358527809381485,
-0.00902861263602972,
-0.0013909320114180446,
-0.011029411107301712,
0.034858327358961105,
0.03394851088523865,
-0.114425890147686,
-0.01152395736426115,
-0.045583102852106094,
0.011534849181771278,
-0.0695248395204544,
-0.02292528934776783,
-0.042145539075136185,
-0.02280363067984581,
-0.012533043511211872,
-3.52008342474619e-8,
-0.04685477167367935,
-0.1168985515832901,
-0.040094465017318726,
-0.07520689070224762,
-0.03391797095537186,
0.08529362827539444,
-0.03332924097776413,
0.07067679613828659,
0.08918553590774536,
0.035363879054784775,
0.06994049996137619,
0.016639074310660362,
-0.05117476359009743,
-0.0642988532781601,
-0.02410992793738842,
-0.0006375541561283171,
0.05581646040081978,
0.036268796771764755,
-0.02370910532772541,
-0.0016194842755794525,
-0.012048049829900265,
0.003474985482171178,
0.034813545644283295,
-0.02382875606417656,
-0.018469497561454773,
-0.048179060220718384,
0.011733409017324448,
0.06916428357362747,
-0.04103504493832588,
-0.0395195446908474,
0.04409482702612877,
-0.09249759465456009,
0.06910958886146545,
0.0343235544860363,
0.06269722431898117,
-0.0017732020933181047,
-0.016189882531762123,
0.006335615646094084,
-0.006864896509796381,
0.14034762978553772,
0.06636422872543335,
0.04414544999599457,
-0.04042229801416397,
0.018215514719486237,
-0.018980052322149277,
-0.019032316282391548,
-0.0067511554807424545,
0.03596596047282219,
-0.01237738411873579,
-0.04130818694829941,
0.011027741245925426,
-0.08871237188577652,
-0.013818765059113503,
-0.04521632567048073,
0.02883906103670597,
0.0025010870303958654,
0.021569857373833656,
0.05555480346083641,
0.08190508931875229,
0.07496282458305359,
0.030874043703079224,
0.033595744520425797,
-0.007571530062705278,
0.03774988278746605
] |
PMID:34232196 | However, further studies should be conducted to validate these findings. | [
0.0028610234148800373,
0.015454933978617191,
0.03585857152938843,
0.03846486657857895,
0.03694482147693634,
0.051550816744565964,
-0.08706744760274887,
0.04564026743173599,
-0.01356724463403225,
0.002667612163349986,
0.038988057523965836,
0.014442670159041882,
-0.03464329242706299,
0.11681483685970306,
0.016992123797535896,
-0.0066433013416826725,
0.04162390157580376,
0.04595864564180374,
-0.007631754036992788,
-0.02443179301917553,
-0.0035083710681647062,
-0.042630720883607864,
0.08645448833703995,
-0.009179290384054184,
-0.06842415779829025,
0.0032298786100000143,
-0.05399307608604431,
0.015093088150024414,
-0.0181321632117033,
0.04315447434782982,
0.043309926986694336,
0.10361449420452118,
-0.04287751019001007,
-0.02274220995604992,
0.050633326172828674,
0.04022514820098877,
-0.0031672148033976555,
0.08098610490560532,
-0.008513824082911015,
0.012595973908901215,
0.019280292093753815,
-0.100143663585186,
0.06080740690231323,
0.01888335309922695,
-0.01912529580295086,
-0.0779724046587944,
-0.06950754672288895,
-0.053567517548799515,
-0.08055147528648376,
0.03799404203891754,
-0.060273412615060806,
-0.023633921518921852,
0.03988197073340416,
0.010902001522481441,
-0.05781670659780502,
-0.06876546889543533,
-0.04108424857258797,
-0.03961538150906563,
0.04463517665863037,
0.0012236994225531816,
0.023230338469147682,
0.016370415687561035,
-0.12881530821323395,
0.017471998929977417,
0.0940583348274231,
0.07063082605600357,
-0.04572584852576256,
-0.10429466515779495,
-0.04257570207118988,
0.07532442361116409,
0.04749152064323425,
-0.0011660924647003412,
-0.03679337725043297,
0.0862874910235405,
-0.01802789233624935,
-0.015503978356719017,
-0.03831581771373749,
0.0014913619961589575,
0.055335745215415955,
-0.10078196972608566,
0.009044190868735313,
0.05448969826102257,
0.02038715034723282,
-0.05012182146310806,
0.017364226281642914,
0.01577714830636978,
-0.04936143755912781,
-0.09500736743211746,
-0.2122088521718979,
0.03229434788227081,
0.1086837649345398,
-0.03532135486602783,
-0.018272673711180687,
0.07070949673652649,
0.039538998156785965,
0.02640334889292717,
-0.04920326918363571,
-0.07529063522815704,
0.08172464370727539,
-0.02047894336283207,
-0.06055273860692978,
-0.0067627583630383015,
-0.024736890569329262,
0.01173903327435255,
-0.0017278380692005157,
-0.03581041470170021,
0.010374498553574085,
-0.0932309702038765,
0.06393236666917801,
0.04034534841775894,
0.050508346408605576,
0.03186862915754318,
-0.02569510042667389,
0.04924793541431427,
0.06276610493659973,
-0.007120331283658743,
-0.014812531881034374,
0.06789659708738327,
0.005878533702343702,
0.03375421091914177,
0.012380690313875675,
-0.010187643580138683,
0.1206052154302597,
-0.08183196187019348,
0.08407603204250336,
-0.11045345664024353,
-0.10029712319374084,
-3.171157191494194e-33,
-0.011424572207033634,
-0.034648507833480835,
-0.003362483810633421,
0.09532679617404938,
-0.02380519174039364,
0.0679529458284378,
-0.051499899476766586,
-0.007554222363978624,
0.019093792885541916,
-0.06442230194807053,
-0.021279549226164818,
0.060588937252759933,
0.039667438715696335,
-0.005795961711555719,
-0.027840256690979004,
0.05778665095567703,
0.0043032062239944935,
0.10889119654893875,
-0.08162441849708557,
0.03587471693754196,
-0.007708679884672165,
-0.07322194427251816,
0.033687230199575424,
0.0038283325266093016,
-0.023474471643567085,
-0.0643019899725914,
0.011244296096265316,
0.022890284657478333,
-0.019430682063102722,
0.006305025424808264,
0.022139260545372963,
-0.02655942365527153,
-0.04868662357330322,
0.002724140416830778,
-0.03845110535621643,
0.16828317940235138,
0.03135978430509567,
0.017514975741505623,
-0.007799385581165552,
0.012042462825775146,
-0.006360779982060194,
0.01718202233314514,
-0.018100034445524216,
0.015730498358607292,
0.06568676978349686,
-0.005972146522253752,
0.010536069050431252,
-0.033472977578639984,
-0.047702815383672714,
0.017930231988430023,
-0.02230871468782425,
0.03901742771267891,
-0.0000690049200784415,
-0.057353436946868896,
-0.016604240983724594,
0.09157273918390274,
-0.04169046878814697,
-0.005210220348089933,
0.01913120225071907,
-0.011997677385807037,
0.09293770045042038,
-0.01605099067091942,
-0.11438742280006409,
-0.02272062748670578,
-0.01992436870932579,
0.08947522938251495,
-0.010385692119598389,
-0.06320173293352127,
-0.016736427322030067,
0.008801320567727089,
-0.07445589452981949,
-0.02584853768348694,
0.03777075931429863,
0.05026489868760109,
-0.029030391946434975,
-0.10303295403718948,
-0.042178962379693985,
0.08350764960050583,
-0.003522554412484169,
-0.0403415746986866,
0.07633954286575317,
-0.06959202140569687,
-0.005647134035825729,
0.05013084411621094,
-0.006672263145446777,
0.03796924650669098,
0.01906939409673214,
-0.014031671918928623,
-0.0026022749952971935,
0.05457130819559097,
0.017308257520198822,
-0.013394635170698166,
-0.023129703477025032,
-0.014236400835216045,
-0.005882818717509508,
1.1012288217892432e-33,
-0.06671777367591858,
0.018029917031526566,
-0.0661250501871109,
0.038388825953006744,
0.029972830787301064,
0.0029236753471195698,
0.0208667553961277,
-0.07489500939846039,
0.0203102920204401,
0.02125086635351181,
0.06982485204935074,
-0.0004593588237185031,
0.01094017457216978,
-0.04826069995760918,
-0.10494216531515121,
-0.010386401787400246,
-0.0178134236484766,
-0.04503105953335762,
0.016313662752509117,
0.026021497324109077,
0.060166969895362854,
0.04417263716459274,
-0.01043807901442051,
0.05024047940969467,
-0.006124166306108236,
0.07878168672323227,
0.0007556034834124148,
-0.0705769956111908,
-0.0939977690577507,
-0.003097307635471225,
0.05622938647866249,
0.0021933603566139936,
-0.06155754625797272,
0.01949995569884777,
0.02077120542526245,
0.013827397488057613,
0.08643332123756409,
-0.07478681206703186,
-0.0057216184213757515,
0.036497075110673904,
0.06739158183336258,
0.06977169215679169,
-0.014495914801955223,
-0.02635989896953106,
-0.007221979089081287,
-0.003377266926690936,
0.03644951060414314,
-0.00523377163335681,
-0.05836428329348564,
-0.012508050538599491,
0.021684914827346802,
0.021893378347158432,
-0.10031758248806,
-0.03902855142951012,
0.008059902116656303,
-0.035151924937963486,
0.0343279093503952,
-0.07651146501302719,
-0.049975451081991196,
0.023711828514933586,
-0.05220533907413483,
0.10114379972219467,
-0.06610880047082901,
0.02194119244813919,
0.03784065693616867,
-0.01931142620742321,
-0.01773054338991642,
-0.023349637165665627,
0.11597450077533722,
-0.028830310329794884,
-0.026335712522268295,
-0.04707401990890503,
-0.05782083794474602,
-0.018769128248095512,
-0.026158612221479416,
-0.020506134256720543,
0.020427774637937546,
-0.035581886768341064,
-0.002928640227764845,
0.023452982306480408,
-0.05555585026741028,
-0.06848514080047607,
0.06590189039707184,
0.018749648705124855,
-0.012286764569580555,
0.025783946737647057,
-0.02932724729180336,
-0.08345718681812286,
-0.043330565094947815,
0.01789289340376854,
-0.05981392413377762,
-0.03265431895852089,
0.003411312587559223,
-0.09219574928283691,
0.022581003606319427,
-2.0937681810551112e-8,
0.023778162896633148,
-0.05520153045654297,
0.06641785055398941,
0.03157665207982063,
-0.015246990136802197,
-0.0020254459232091904,
-0.046495307236909866,
-0.0009634789312258363,
-0.013692743144929409,
-0.021861521527171135,
0.00233286595903337,
0.023544101044535637,
-0.0038141105324029922,
0.05785449594259262,
0.028505608439445496,
-0.04425499588251114,
0.12704871594905853,
-0.006799780298024416,
-0.06691480427980423,
0.020049747079610825,
0.015621519647538662,
0.09302244335412979,
0.04271690547466278,
-0.011696100234985352,
0.006097759585827589,
0.05830153450369835,
0.015498757362365723,
0.08279367536306381,
-0.102895088493824,
0.011837578378617764,
0.031542740762233734,
0.011356278322637081,
-0.014192628674209118,
-0.0638461783528328,
0.04000719264149666,
-0.05157633498311043,
0.07083600759506226,
0.05714409798383713,
0.0389443077147007,
0.07625698298215866,
-0.039271365851163864,
-0.005685719195753336,
0.016802022233605385,
0.12129806727170944,
0.013742657378315926,
-0.09564263373613358,
-0.042685043066740036,
0.055779311805963516,
-0.028297796845436096,
-0.006900283508002758,
-0.01127701997756958,
-0.029770290479063988,
0.05906728282570839,
-0.0011811681324616075,
-0.02387140318751335,
0.07803165912628174,
-0.002641822211444378,
0.019623493775725365,
-0.041634730994701385,
-0.01944584585726261,
0.13126082718372345,
-0.024812184274196625,
0.10124988853931427,
-0.017012527212500572
] |
PMID:30135434 | Increasing evidence indicates that human cytomegalovirus (HCMV) populations under the influence of host environment, can either be stable or rapidly differentiating, leading to tissue compartment colonization. | [
0.02447221614420414,
0.006265273783355951,
0.007223939057439566,
0.008629598654806614,
0.026187023147940636,
0.007606559433043003,
-0.0031695838551968336,
0.032729536294937134,
-0.07272070646286011,
0.03241686150431633,
-0.003496550489217043,
0.001954801846295595,
0.06897568702697754,
0.11602068692445755,
-0.04302075132727623,
-0.017896097153425217,
0.005912016145884991,
-0.02744114212691784,
0.02876349166035652,
0.03410293534398079,
-0.08075761049985886,
0.014915484935045242,
0.045251451432704926,
-0.007588193751871586,
-0.06325294077396393,
0.006312885787338018,
-0.004787886515259743,
0.11917223781347275,
0.03468692675232887,
0.012283818796277046,
-0.05994216725230217,
-0.015413220971822739,
0.04403390735387802,
0.034668032079935074,
-0.009951653890311718,
0.08032079041004181,
-0.09116516262292862,
-0.03035544604063034,
-0.024598827585577965,
0.011280741542577744,
0.011050138622522354,
0.020465601235628128,
-0.007620648015290499,
0.0797923356294632,
0.04549466446042061,
0.039801012724637985,
-0.05007386580109596,
0.015193343162536621,
0.0013147006975486875,
-0.048328056931495667,
0.06593645364046097,
0.09433174878358841,
0.0035392807330936193,
0.043485015630722046,
-0.08940675109624863,
0.01889844238758087,
-0.05695800855755806,
-0.03202386572957039,
0.009468555450439453,
-0.06543296575546265,
-0.020006408914923668,
0.09723867475986481,
0.0016249220352619886,
0.02514549531042576,
0.02961719036102295,
-0.11516965180635452,
0.008419407531619072,
0.07803801447153091,
0.04460202902555466,
0.039741646498441696,
0.0030128778889775276,
0.014820846728980541,
-0.11742015928030014,
0.010607979260385036,
-0.025310255587100983,
0.03723515197634697,
0.041657671332359314,
-0.031378258019685745,
0.035357873886823654,
0.0269455723464489,
0.01586325094103813,
0.003693543840199709,
0.09202525019645691,
-0.010705393739044666,
-0.1204945296049118,
-0.053351715207099915,
-0.02369319275021553,
0.003486412111669779,
-0.08551651239395142,
0.06406231224536896,
0.041319191455841064,
0.0057789916172623634,
0.06662316620349884,
0.040683094412088394,
-0.10315492749214172,
0.02357180044054985,
0.0495474599301815,
0.034405551850795746,
0.06661831587553024,
0.005857214331626892,
-0.07849377393722534,
-0.08135373145341873,
0.0044740731827914715,
-0.006524397525936365,
0.08847951889038086,
-0.01268021110445261,
0.022544074803590775,
0.04265629127621651,
0.03698407858610153,
0.03706495836377144,
0.0213950015604496,
0.09132726490497589,
-0.024213964119553566,
0.022092320024967194,
0.08779643476009369,
0.06764980405569077,
-0.013654571957886219,
-0.05087023600935936,
0.031592391431331635,
0.0009371544001623988,
-0.0064224558882415295,
-0.07561851292848587,
0.02863289974629879,
-0.012241857126355171,
-0.009690468199551105,
-0.007889986038208008,
0.005759518127888441,
3.5572444998486837e-34,
0.02456912025809288,
-0.10881952196359634,
0.0858602449297905,
0.06425856053829193,
-0.05450586974620819,
0.011379379779100418,
0.0816803127527237,
0.01756277307868004,
-0.0230423491448164,
-0.05515353009104729,
-0.017180101945996284,
-0.033901166170835495,
0.04352235049009323,
0.07392292469739914,
-0.08385603874921799,
0.031476475298404694,
-0.07897473126649857,
0.009508557617664337,
-0.0671754777431488,
0.034426964819431305,
0.019815955311059952,
-0.07073014229536057,
0.0467502661049366,
0.02402285858988762,
0.08359253406524658,
-0.02594059891998768,
-0.0753559097647667,
0.04450133070349693,
0.07468117773532867,
-0.02555936388671398,
-0.06334337592124939,
-0.0003974342253059149,
-0.03766585513949394,
0.0005203230539336801,
-0.0009026494226418436,
0.08157642185688019,
-0.0026765200309455395,
-0.04465921223163605,
-0.02509613148868084,
0.003031427739188075,
-0.032996173948049545,
0.006963353604078293,
0.05360310152173042,
-0.10731024295091629,
0.07610401511192322,
-0.031244879588484764,
-0.06361692398786545,
-0.04968583956360817,
-0.15758447349071503,
-0.02583128772675991,
0.020154710859060287,
0.07317744195461273,
0.018046902492642403,
-0.05360068753361702,
-0.010685834102332592,
-0.030997250229120255,
0.06602705270051956,
0.049592889845371246,
-0.044454146176576614,
-0.07953549921512604,
0.06216292455792427,
0.05557139590382576,
0.026462409645318985,
0.0780320093035698,
0.08006421476602554,
-0.028704499825835228,
0.06108517572283745,
-0.005969459190964699,
-0.11522114276885986,
0.0916827842593193,
-0.020953886210918427,
0.01722542941570282,
-0.05671902373433113,
-0.07617860287427902,
0.02341730333864689,
-0.08269309997558594,
-0.04873758181929588,
-0.061601266264915466,
-0.03688214719295502,
-0.01711081713438034,
-0.04755886644124985,
-0.05998498201370239,
0.025803251191973686,
0.013455059379339218,
0.01825535297393799,
-0.017260925844311714,
0.024996032938361168,
-0.0543077252805233,
0.013721379451453686,
0.05575791746377945,
0.009198841638863087,
0.026919635012745857,
-0.01370372623205185,
0.02075934037566185,
-0.05744791403412819,
-2.764935180195805e-33,
-0.03292930871248245,
0.006741839926689863,
-0.02308601140975952,
0.01708267442882061,
-0.02280055545270443,
0.08345939964056015,
-0.017355745658278465,
0.05046206712722778,
-0.02203153260052204,
-0.01971505768597126,
-0.013947988860309124,
0.03723660111427307,
0.008527352474629879,
0.062464404851198196,
-0.03397220000624657,
-0.04813998192548752,
0.011624799109995365,
0.0905667319893837,
-0.044246166944503784,
0.11343642324209213,
-0.07236962020397186,
-0.0064675831235945225,
-0.004669432993978262,
-0.03346233814954758,
-0.03284898027777672,
-0.06679506599903107,
-0.05780750513076782,
0.06221695616841316,
-0.04108733683824539,
0.03618856519460678,
-0.00579351419582963,
0.05498524010181427,
-0.04097532480955124,
-0.008088292554020882,
0.04390432685613632,
0.06683745980262756,
-0.019832639023661613,
-0.0604875348508358,
0.07609293609857559,
0.039164867252111435,
-0.009340050630271435,
-0.009279800578951836,
-0.004250028170645237,
0.004981142934411764,
0.026290107518434525,
0.14384278655052185,
0.027671609073877335,
0.0494760200381279,
0.05218600854277611,
0.055159617215394974,
-0.01149019319564104,
-0.03706785663962364,
-0.028465857729315758,
0.00678236735984683,
-0.05386503413319588,
0.00041898226481862366,
-0.006097456440329552,
-0.040411848574876785,
0.07945162802934647,
-0.012872149236500263,
-0.0005568443448282778,
-0.02511276863515377,
-0.037065859884023666,
-0.027754493057727814,
-0.04113662242889404,
0.09306076914072037,
0.04984010010957718,
0.08389320224523544,
-0.050521332770586014,
-0.04148953780531883,
0.031712088733911514,
-0.06589556485414505,
-0.00039021301199682057,
-0.008172586560249329,
-0.020240727812051773,
-0.031397294253110886,
0.0152109544724226,
0.005978558678179979,
0.01866036280989647,
-0.022153310477733612,
0.09561289101839066,
-0.05267518758773804,
0.06304715573787689,
-0.01985943876206875,
0.06296038627624512,
-0.04075933247804642,
-0.020278505980968475,
-0.02766827493906021,
-0.11605703830718994,
0.03970031440258026,
-0.039742011576890945,
-0.06919855624437332,
-0.006377294193953276,
-0.15136602520942688,
-0.06878495961427689,
-3.015870575495683e-8,
0.06583398580551147,
-0.03447934240102768,
-0.015983572229743004,
-0.03913486748933792,
-0.042554039508104324,
0.02345125935971737,
-0.028444532305002213,
-0.051023244857788086,
0.065401092171669,
0.12337471544742584,
0.007622185163199902,
0.029698075726628304,
-0.012304561212658882,
0.01784748211503029,
0.006883109454065561,
0.02649025432765484,
-0.10748133063316345,
0.02344386838376522,
-0.06623714417219162,
0.006004934199154377,
-0.06557376682758331,
-0.0014756674645468593,
0.0047336663119494915,
0.09089354425668716,
0.055020228028297424,
0.00550420256331563,
0.02317970059812069,
-0.026542961597442627,
0.07145106047391891,
-0.0939493402838707,
0.02174995467066765,
0.054368238896131516,
-0.02729734592139721,
0.07646061480045319,
-0.016368871554732323,
0.0029088056180626154,
0.014217277057468891,
-0.003032200736925006,
0.10640374571084976,
-0.06502007693052292,
-0.029651837423443794,
-0.06914177536964417,
-0.037913814187049866,
-0.03079848550260067,
-0.027908680960536003,
-0.05248824506998062,
-0.02407907322049141,
-0.002363088307902217,
-0.022488249465823174,
-0.09369892627000809,
-0.02351308986544609,
-0.06633943319320679,
-0.03059639036655426,
-0.015117625705897808,
0.03231851011514664,
0.0238027460873127,
0.03569380193948746,
-0.06532055884599686,
0.08845227211713791,
-0.08726444095373154,
-0.0772392749786377,
0.006092715077102184,
0.003261314705014229,
-0.05175790563225746
] |
PMID:30135434 | We isolated previously from a 30-years old pregnant woman, a clinical isolate of HCMV, that we refered to as the HCMV-DB strain (accession number KT959235). | [
-0.06398925930261612,
-0.02694728784263134,
-0.06682240962982178,
0.00020747759845107794,
0.033842675387859344,
0.07142376899719238,
-0.04900581017136574,
0.0990147516131401,
-0.05390562117099762,
-0.03629684820771217,
0.0006743362755514681,
-0.053856153041124344,
-0.00434537697583437,
0.012849378399550915,
-0.05020200088620186,
-0.0009267093846574426,
-0.027364211156964302,
-0.08653778582811356,
0.0519435852766037,
0.03453805670142174,
-0.12173514068126678,
0.04532326012849808,
0.026721127331256866,
0.021586362272500992,
0.015806695446372032,
0.043572381138801575,
0.01708885096013546,
0.07485035806894302,
0.013903056271374226,
-0.044746607542037964,
-0.03315979242324829,
0.020397327840328217,
0.06109587475657463,
-0.0009185909293591976,
-0.036070287227630615,
0.06307078897953033,
-0.07099910825490952,
0.027602069079875946,
0.00960826687514782,
0.011994147673249245,
0.013607493601739407,
-0.00013806302740704268,
-0.034579161554574966,
-0.023578032851219177,
0.027311215177178383,
0.045166634023189545,
-0.07407134026288986,
0.02965875342488289,
0.020879073068499565,
0.05165783688426018,
0.022991107776761055,
0.00519862724468112,
-0.0013800348388031125,
0.08987988531589508,
-0.043004438281059265,
-0.08047876507043839,
-0.03470074012875557,
0.017042389139533043,
0.020984863862395287,
0.06162446737289429,
-0.00024413567734882236,
0.08420350402593613,
0.03296704962849617,
0.009934783913195133,
0.02011820115149021,
-0.023265140131115913,
0.10832303762435913,
0.00992901436984539,
0.10080451518297195,
-0.09134491533041,
0.009405761957168579,
-0.012703405693173409,
-0.028831979259848595,
0.07560503482818604,
-0.043057095259428024,
0.03790849447250366,
0.005524773616343737,
-0.023364806547760963,
0.02963224984705448,
0.007885156199336052,
-0.07269451022148132,
0.05889341980218887,
0.021568724885582924,
0.018494561314582825,
-0.0923018530011177,
0.0021800582762807608,
-0.04373821243643761,
0.026366742327809334,
0.00863576214760542,
0.05694274976849556,
-0.03657462075352669,
-0.009768875315785408,
0.08883003890514374,
0.023087119683623314,
0.01566503755748272,
0.0049340929836034775,
0.031264085322618484,
0.026501329615712166,
0.08319980651140213,
0.014988177455961704,
-0.0020620147697627544,
0.03559843450784683,
-0.0117925014346838,
0.02270340546965599,
0.021442804485559464,
-0.042673803865909576,
-0.02708733268082142,
0.010533100925385952,
0.010842511430382729,
-0.004837850574404001,
0.03705370053648949,
0.041346475481987,
-0.013341732323169708,
-0.1143295168876648,
0.050262030214071274,
0.028180349618196487,
0.10026099532842636,
-0.05876915156841278,
-0.0019088052213191986,
0.010285379365086555,
-0.0062253461219370365,
-0.02636510506272316,
0.06403040140867233,
-0.057708095759153366,
-0.06597579270601273,
-0.04401686415076256,
-0.010966919362545013,
-1.4289106372149218e-33,
-0.037599578499794006,
-0.07390031218528748,
0.09590179473161697,
0.014571831561625004,
-0.02368844486773014,
0.07505758106708527,
0.024092916399240494,
0.025491178035736084,
-0.030155016109347343,
-0.07811128348112106,
-0.03798540309071541,
-0.0591152049601078,
0.011174604296684265,
-0.051954466849565506,
-0.04939857870340347,
0.02591128647327423,
-0.010167324915528297,
0.007816897705197334,
-0.07083562761545181,
0.04891904816031456,
-0.0024523672182112932,
0.04736781120300293,
0.054382793605327606,
-0.0007477662875317037,
0.06373754888772964,
-0.03482649102807045,
-0.013822945766150951,
-0.0056848530657589436,
0.04020513594150543,
-0.005765403620898724,
-0.05815349146723747,
-0.041591159999370575,
0.01437107753008604,
-0.060489535331726074,
-0.03367098420858383,
0.042976707220077515,
-0.10224036127328873,
-0.06444892287254333,
-0.01927473396062851,
0.08762598782777786,
0.020582333207130432,
0.007201508618891239,
0.07083430141210556,
-0.0753658339381218,
0.03421396017074585,
0.0065707978792488575,
-0.05436102673411369,
-0.033647824078798294,
-0.07360834628343582,
-0.07740474492311478,
-0.04295115917921066,
0.009512171149253845,
-0.04166995733976364,
-0.022197289392352104,
-0.015337204560637474,
0.014841482043266296,
0.033343829214572906,
0.01122901402413845,
0.0064752185717225075,
-0.004733233712613583,
0.09832298010587692,
0.08208276331424713,
-0.004661001265048981,
0.048232607543468475,
-0.020097361877560616,
-0.14843134582042694,
-0.040316566824913025,
0.032275453209877014,
-0.05613168701529503,
0.0034436213318258524,
-0.0440400131046772,
0.011783287860453129,
0.00654442235827446,
-0.062243953347206116,
0.05005526542663574,
-0.03784646838903427,
-0.0029890157748013735,
-0.06442050635814667,
0.010134592652320862,
-0.09057280421257019,
-0.06449880450963974,
0.01522450428456068,
0.08596032112836838,
0.06985747814178467,
-0.100075364112854,
0.0221401359885931,
0.013589771464467049,
-0.002341917250305414,
-0.07117920368909836,
0.008534730412065983,
-0.022965142503380775,
0.03637891262769699,
-0.023193342611193657,
-0.027730228379368782,
0.010873952880501747,
-1.7850364771946227e-33,
0.01922794245183468,
0.013165588490664959,
0.006125336512923241,
-0.052884526550769806,
0.004199566785246134,
0.044602666050195694,
0.0032754819840192795,
0.09279453009366989,
-0.06097651645541191,
0.033923424780368805,
0.08473271876573563,
-0.06259816884994507,
0.054700564593076706,
-0.005691486410796642,
-0.01167889591306448,
0.02202834002673626,
0.0029875661712139845,
0.100811667740345,
-0.047204986214637756,
0.10420962423086166,
-0.011184623464941978,
-0.03155718743801117,
0.010363694280385971,
-0.06756460666656494,
0.07405205816030502,
-0.05347114056348801,
0.04839860275387764,
0.0024040094576776028,
0.023740675300359726,
0.07680296897888184,
-0.07573757320642471,
0.050180334597826004,
-0.01893281191587448,
-0.019752953201532364,
0.026379307731986046,
-0.045833662152290344,
-0.029091402888298035,
-0.06369516998529434,
0.04892055690288544,
-0.08002367615699768,
-0.03384961187839508,
0.08064399659633636,
-0.05338994413614273,
-0.011929363943636417,
-0.019493645057082176,
0.15754790604114532,
0.07807207107543945,
0.08166302740573883,
0.05798471346497536,
-0.027519145980477333,
0.0265643447637558,
-0.03557508438825607,
-0.047844622284173965,
0.056323856115341187,
-0.017119569703936577,
-0.039143629372119904,
0.012719420716166496,
0.06276635080575943,
0.02411654405295849,
-0.020184878259897232,
-0.009901696816086769,
0.022609395906329155,
-0.07146492600440979,
-0.0423162505030632,
-0.016692034900188446,
0.02266271412372589,
-0.015220407396554947,
0.009894654154777527,
-0.02653161622583866,
-0.1136794239282608,
0.010919341817498207,
-0.012944807298481464,
0.05282273516058922,
-0.028870847076177597,
-0.0038851809222251177,
-0.08414692431688309,
-0.07488707453012466,
-0.05011730641126633,
0.02548934333026409,
-0.01540409866720438,
0.10137668997049332,
-0.08906601369380951,
0.07752786576747894,
-0.029301848262548447,
0.10427694022655487,
-0.05446084216237068,
-0.0035162330605089664,
-0.048772815614938736,
-0.07198618352413177,
0.0378095917403698,
-0.057308629155159,
0.01658795401453972,
-0.1443071812391281,
-0.037262603640556335,
0.009503531269729137,
-3.3077117933544287e-8,
0.1287967562675476,
-0.08405698090791702,
-0.025996675714850426,
-0.051724907010793686,
0.0469605028629303,
-0.0025742300786077976,
-0.07664567977190018,
-0.05800546333193779,
0.05137436464428902,
0.06612008810043335,
-0.0015775265637785196,
-0.03655209392309189,
-0.03920838609337807,
0.023997334763407707,
-0.007599950768053532,
0.04275194928050041,
-0.04310453683137894,
0.1055263802409172,
-0.018697232007980347,
0.06707794964313507,
-0.05607733875513077,
-0.019642921164631844,
0.03987621143460274,
0.028881413862109184,
0.026239853352308273,
0.030537141487002373,
0.005562363192439079,
0.0024224850349128246,
0.06914111971855164,
-0.1389896720647812,
0.024734029546380043,
0.0755736455321312,
-0.005605736747384071,
-0.014060325920581818,
-0.03377772495150566,
0.06681601703166962,
-0.02959287539124489,
0.05042671412229538,
0.0031399307772517204,
0.05322270840406418,
-0.006762503646314144,
-0.1265323907136917,
-0.022733913734555244,
-0.006830298341810703,
-0.0026538281235843897,
-0.04397363215684891,
-0.024828990921378136,
0.020317085087299347,
-0.04252784699201584,
-0.0968293696641922,
-0.0029538231901824474,
-0.041430436074733734,
0.06663999706506729,
-0.005463658832013607,
0.06118175387382507,
0.062458839267492294,
0.03976327180862427,
-0.11155640333890915,
-0.018036939203739166,
-0.039531100541353226,
-0.013111840933561325,
-0.04818892106413841,
0.12623289227485657,
0.008389187976717949
] |
PMID:30135434 | The HCMV-DB clinical isolate demonstrated its ability to infect primary macrophages and to upregulate the proto-oncogene Bcl-3. | [
-0.0955667644739151,
-0.012072598561644554,
-0.03156512230634689,
-0.03782785311341286,
-0.014666150324046612,
0.07959961146116257,
-0.0649472177028656,
0.07003103941679001,
-0.004124072380363941,
0.01688212715089321,
-0.09168854355812073,
-0.0732618197798729,
0.09576672315597534,
0.006303986068814993,
-0.015974218025803566,
0.002028270624577999,
0.019300078973174095,
0.02069595642387867,
-0.002287948504090309,
0.02201223373413086,
-0.10308898240327835,
0.00164108257740736,
0.04260473698377609,
0.049882352352142334,
-0.02649284340441227,
-0.009070769883692265,
0.04740193486213684,
0.04751577228307724,
0.020889492705464363,
-0.02732633613049984,
-0.01605326496064663,
0.018540436401963234,
0.06891965866088867,
0.014847160317003727,
-0.021177204325795174,
-0.002086452441290021,
-0.04759547859430313,
0.0413549542427063,
-0.04439399391412735,
-0.018151691183447838,
0.0076668099500238895,
0.014594237320125103,
-0.04963485896587372,
-0.014384043402969837,
0.0505717471241951,
0.050102222710847855,
-0.019797081127762794,
0.04340437054634094,
0.07792846858501434,
-0.015976432710886,
0.008192275650799274,
0.02123505435883999,
-0.021976053714752197,
0.11572463065385818,
-0.0933847650885582,
0.053570281714200974,
-0.05686564743518829,
0.011830303817987442,
0.08985568583011627,
0.002864291425794363,
-0.06495438516139984,
-0.016448309645056725,
0.06968982517719269,
0.03771679475903511,
-0.023787688463926315,
-0.02097463607788086,
0.011604269966483116,
0.009832153096795082,
-0.06409870833158493,
0.001936530345119536,
-0.07019409537315369,
-0.030913036316633224,
-0.023943480104207993,
0.08894987404346466,
-0.046440303325653076,
0.035094548016786575,
0.07054775953292847,
-0.07417464256286621,
0.032569415867328644,
0.04787539690732956,
-0.03645554929971695,
-0.006642547901719809,
-0.002648774068802595,
0.06539996713399887,
-0.009209812618792057,
-0.031768180429935455,
-0.0652458444237709,
-0.03356410935521126,
-0.01612187922000885,
0.09894970059394836,
-0.02322153002023697,
0.013305185362696648,
0.12310786545276642,
0.04733062908053398,
0.010240627452731133,
0.013049391098320484,
0.0972234308719635,
0.04243787005543709,
0.153559148311615,
-0.018388452008366585,
-0.07240914553403854,
-0.026362629607319832,
0.013730296865105629,
0.001739127328619361,
0.003037034533917904,
0.03034326806664467,
-0.017657553777098656,
-0.04425416886806488,
0.07014340907335281,
0.0008090105256997049,
0.10963751375675201,
-0.014977059327065945,
0.03227038308978081,
-0.07910820841789246,
0.03029964305460453,
0.07930455356836319,
0.0811518058180809,
-0.08801541477441788,
0.017979344353079796,
-0.06572990864515305,
0.034701038151979446,
-0.12147998809814453,
0.006931531708687544,
-0.10062656551599503,
-0.04468977078795433,
-0.022021599113941193,
0.054751165211200714,
-1.3529246619968536e-33,
-0.027727913111448288,
-0.06779108941555023,
0.03248134255409241,
0.08388885110616684,
-0.016941528767347336,
0.06344549357891083,
0.07426165044307709,
0.05029933154582977,
-0.031074240803718567,
-0.10571426898241043,
0.01507589966058731,
-0.053312595933675766,
0.04273541271686554,
0.058330267667770386,
-0.07434496283531189,
0.006707304157316685,
-0.009041937068104744,
-0.05398619547486305,
-0.07831691950559616,
-0.011307491920888424,
0.008143147453665733,
-0.030153973028063774,
0.05353605002164841,
-0.040487419813871384,
0.046492453664541245,
0.02107096277177334,
-0.0552680529654026,
0.004427584819495678,
0.07826334238052368,
-0.012500951066613197,
-0.011288444511592388,
0.03817889839410782,
-0.04602573439478874,
0.0004416145966388285,
-0.07664145529270172,
0.05410880595445633,
-0.0921102836728096,
-0.027558792382478714,
-0.013093852438032627,
0.06830296665430069,
-0.016158146783709526,
-0.03368830680847168,
-0.038239847868680954,
-0.07391981035470963,
-0.0027415850199759007,
0.005878121592104435,
-0.07681865245103836,
0.004982886370271444,
-0.034444235265254974,
-0.04994862899184227,
0.08255459368228912,
-0.006792077794671059,
-0.034365370869636536,
-0.060206975787878036,
0.04298766329884529,
0.026571961119771004,
-0.06753860414028168,
0.03523067384958267,
0.018036430701613426,
-0.010457932017743587,
0.07700157165527344,
0.07319177687168121,
0.01812824234366417,
0.1377786546945572,
0.057697225362062454,
-0.07830623537302017,
-0.04913732782006264,
0.03648104891180992,
-0.0976579412817955,
-0.01057757344096899,
0.07436485588550568,
0.08101149648427963,
0.018428442999720573,
-0.0750831589102745,
0.01845237798988819,
-0.01629151776432991,
-0.0007443394861184061,
-0.029498932883143425,
0.010487482883036137,
0.02247759886085987,
-0.00005407291973824613,
-0.007137654814869165,
0.06263844668865204,
0.09211806952953339,
-0.06649784743785858,
-0.040177684277296066,
0.021784136071801186,
-0.018199851736426353,
-0.07673382759094238,
-0.032616596668958664,
0.03494882583618164,
-0.03138848394155502,
-0.014262974262237549,
0.06749583035707474,
-0.09285929054021835,
-5.244439577189827e-34,
0.03612840175628662,
-0.014810523949563503,
0.011322957463562489,
-0.007157796528190374,
-0.046416617929935455,
0.09857861697673798,
0.07878363132476807,
-0.01761542819440365,
-0.04266505315899849,
0.004654184449464083,
0.04244522750377655,
-0.014718911610543728,
-0.030632803216576576,
0.057662829756736755,
-0.023829542100429535,
-0.07019007205963135,
-0.04362662136554718,
-0.013440374284982681,
-0.1115194708108902,
0.05783034861087799,
0.05020945146679878,
-0.030806846916675568,
-0.024012623354792595,
0.014111769385635853,
-0.006254096049815416,
-0.02207707054913044,
-0.08379150927066803,
0.027816154062747955,
-0.06756345927715302,
0.1558501124382019,
0.008951365947723389,
0.10178516060113907,
0.0315910242497921,
-0.0663769394159317,
0.01889055408537388,
0.033108945935964584,
-0.01893746852874756,
-0.06029042229056358,
0.06993632763624191,
-0.030754929408431053,
-0.05389667674899101,
-0.005460775922983885,
-0.07361476123332977,
-0.0621490404009819,
0.03004295378923416,
0.13966059684753418,
0.057600852102041245,
0.09020490199327469,
0.08662362396717072,
-0.002264892915263772,
0.005254534538835287,
0.02076074853539467,
-0.0034028710797429085,
0.05416885390877724,
-0.022100694477558136,
-0.03235790878534317,
0.029032733291387558,
-0.041521698236465454,
0.07072127610445023,
-0.0896516963839531,
-0.02280922420322895,
-0.017095057293772697,
0.029435306787490845,
-0.01567092351615429,
-0.0029085385613143444,
0.13254877924919128,
-0.005932665430009365,
0.033991504460573196,
0.03103114292025566,
-0.06395435333251953,
-0.04132689908146858,
-0.025738807395100594,
0.006576345767825842,
-0.07634374499320984,
-0.0482478067278862,
-0.015408772975206375,
-0.015232904814183712,
-0.03686533495783806,
-0.00013319689605850726,
0.047196563333272934,
0.052024081349372864,
-0.06231082230806351,
0.03641819208860397,
-0.01213878858834505,
0.04108418896794319,
-0.026496265083551407,
-0.053660858422517776,
-0.0536847747862339,
-0.04122048616409302,
0.046202659606933594,
-0.1056051254272461,
-0.016305770725011826,
-0.05863240361213684,
0.032963238656520844,
-0.015275825746357441,
-2.6945372155751102e-8,
0.11133699864149094,
-0.024001730605959892,
-0.004154645837843418,
-0.06104719638824463,
0.01350252702832222,
-0.007158452179282904,
-0.07869331538677216,
-0.03045235201716423,
0.06728823482990265,
0.04565899819135666,
0.006526951212435961,
-0.0489649698138237,
0.013019267469644547,
0.03033146634697914,
0.08922134339809418,
0.021607426926493645,
-0.04671161621809006,
-0.025170860812067986,
-0.008287540636956692,
-0.005609509535133839,
-0.02005848102271557,
0.024392947554588318,
0.01914491504430771,
-0.005911022424697876,
0.11941711604595184,
-0.04296742007136345,
-0.03971888870000839,
0.019182071089744568,
0.032098475843667984,
-0.06255006790161133,
-0.04949278384447098,
0.03755967319011688,
-0.03356200456619263,
0.006542375311255455,
0.009612868539988995,
-0.02222524955868721,
0.006337753962725401,
-0.012703986838459969,
0.025329962372779846,
0.009179271757602692,
0.033658839762210846,
-0.0053154705092310905,
-0.0248868428170681,
-0.03969476372003555,
-0.0859593078494072,
-0.03676706925034523,
-0.054310981184244156,
-0.02753041684627533,
-0.03443996608257294,
-0.08136539161205292,
-0.002373083960264921,
0.0019912493880838156,
0.02734929509460926,
0.060999684035778046,
0.012334171682596207,
0.01882248930633068,
0.015069583430886269,
-0.05906219035387039,
0.010171954520046711,
-0.05306488275527954,
-0.047683920711278915,
-0.0005839045625180006,
0.055336348712444305,
0.008163278922438622
] |
PMID:30135434 | We observed in this study that the genome of HCMV-DB strain is close to the genomes of other primary clinical isolates including the Toledo and the JP strains with the later having been isolated from a glandular tissue, the prostate. | [
-0.06313249468803406,
-0.0312701053917408,
-0.10782953351736069,
-0.042636215686798096,
0.004222954157739878,
0.017229128628969193,
-0.08329132199287415,
0.0417870469391346,
-0.08324630558490753,
-0.016156526282429695,
0.03450712934136391,
-0.015098805539309978,
0.0075892857275903225,
0.05015793815255165,
-0.0016557086491957307,
-0.04750323295593262,
-0.08856796473264694,
-0.06989704817533493,
0.0842069536447525,
0.00982413999736309,
-0.08704771846532822,
0.08093651384115219,
0.060472726821899414,
0.02237722836434841,
-0.04265563189983368,
-0.013415835797786713,
0.07444553077220917,
0.11762969195842743,
-0.01873098313808441,
-0.057589367032051086,
0.003276263363659382,
-0.010025032795965672,
0.08933495730161667,
0.01019245944917202,
-0.0005878458032384515,
0.00230911816470325,
-0.06508835405111313,
0.03135658800601959,
0.004382899962365627,
0.01280542928725481,
0.025871440768241882,
-0.019721949473023415,
-0.012797546572983265,
0.037064675241708755,
0.07119680196046829,
0.07387154549360275,
-0.07571504265069962,
0.021305711939930916,
0.041424572467803955,
0.06648995727300644,
-0.051808249205350876,
0.009075154550373554,
0.03825559839606285,
0.07919870316982269,
-0.059566326439380646,
-0.0840098112821579,
-0.010435180738568306,
0.029923904687166214,
0.03630449250340462,
0.05393355339765549,
0.004763551522046328,
0.02307610772550106,
-0.008904949761927128,
-0.010938683524727821,
0.015067039988934994,
-0.03538919985294342,
0.09167569130659103,
-0.0007535592885687947,
0.02053978107869625,
-0.04836125299334526,
0.043877340853214264,
-0.0410604290664196,
-0.049743764102458954,
0.07170002907514572,
-0.10111423581838608,
0.02666669897735119,
-0.029546627774834633,
0.01955355703830719,
0.010722637176513672,
-0.027614392340183258,
-0.07394377887248993,
-0.0010073048761114478,
0.03969413414597511,
-0.005545390769839287,
-0.1112721711397171,
-0.014173699542880058,
0.010385461151599884,
0.04229504242539406,
-0.07316629588603973,
0.08275092393159866,
-0.05054706335067749,
-0.04219768941402435,
0.08065763860940933,
-0.011240691877901554,
0.010269423015415668,
0.04132844880223274,
0.07623165100812912,
0.023279843851923943,
0.07494029402732849,
-0.01746734045445919,
-0.02198904938995838,
-0.01853741519153118,
0.006174899637699127,
0.00198135687969625,
0.03069688007235527,
-0.016765041276812553,
-0.028454817831516266,
0.01999291591346264,
-0.007043426390737295,
0.03621726855635643,
0.10054309666156769,
0.06860985606908798,
-0.027812596410512924,
-0.09680479764938354,
0.03030109778046608,
-0.0310982633382082,
0.040520865470170975,
-0.03705865517258644,
-0.05343169718980789,
0.007604467216879129,
-0.01640232279896736,
-0.007943871431052685,
0.08257944881916046,
-0.005944032687693834,
-0.04184938222169876,
-0.0007046237587928772,
-0.026930110529065132,
-3.6571565146340375e-33,
0.002875053556635976,
-0.09177318960428238,
0.056555453687906265,
-0.0061362022534012794,
0.0100972605869174,
0.02800774946808815,
0.061233121901750565,
0.02699780836701393,
-0.05935579538345337,
-0.10522159188985825,
-0.020837200805544853,
-0.016560420393943787,
0.06322584301233292,
-0.0012520685559138656,
-0.087362140417099,
0.005971232894808054,
0.006920729298144579,
0.06150323525071144,
-0.11854631453752518,
0.02856856770813465,
0.00914621539413929,
0.07047449052333832,
0.06519245356321335,
-0.010622667148709297,
0.019437512382864952,
0.025235895067453384,
-0.06204995512962341,
-0.03671704977750778,
0.035574477165937424,
-0.005757531616836786,
-0.06176798418164253,
0.0015815504593774676,
0.029627738520503044,
0.017343202605843544,
0.05649411305785179,
0.06777666509151459,
-0.05076111853122711,
-0.09745628386735916,
0.006302687805145979,
0.06061098724603653,
0.04080824553966522,
-0.009509524330496788,
0.0925213024020195,
-0.06302908807992935,
0.026616763323545456,
-0.027103103697299957,
-0.03829078748822212,
-0.0778060108423233,
-0.10277258604764938,
-0.06160968169569969,
-0.06721926480531693,
0.010517328046262264,
-0.04256618022918701,
-0.041826605796813965,
-0.0323767215013504,
-0.01735127530992031,
-0.016087012365460396,
0.04155738279223442,
0.04674094542860985,
0.03301842510700226,
0.03645527362823486,
0.08405479043722153,
-0.026585981249809265,
0.026307031512260437,
0.004005771595984697,
-0.11601263284683228,
-0.09865205734968185,
0.04334953799843788,
-0.04296659678220749,
0.07972603291273117,
0.03436332941055298,
-0.014348385855555534,
0.05473712459206581,
-0.10173531621694565,
0.05262843146920204,
0.00934502761811018,
-0.006084310822188854,
-0.04142318665981293,
-0.052792567759752274,
-0.03498510643839836,
-0.07612759619951248,
0.03428719937801361,
0.009630762971937656,
0.03275512158870697,
-0.0680883526802063,
0.00996305886656046,
0.04446890205144882,
0.006768530234694481,
-0.08709702640771866,
0.009178436361253262,
-0.019570311531424522,
0.04591269791126251,
-0.023712441325187683,
-0.025393027812242508,
0.0020674013067036867,
-5.756773739043432e-34,
0.027541384100914,
0.023177754133939743,
0.05765364319086075,
-0.01029584277421236,
-0.06869106739759445,
0.05683428421616554,
0.0067030382342636585,
0.018162759020924568,
-0.08555230498313904,
0.01131365541368723,
0.052647076547145844,
-0.05669783428311348,
0.034181345254182816,
-0.03303026035428047,
-0.05620408058166504,
0.01846271939575672,
0.01471306849271059,
0.07080371677875519,
-0.07399635761976242,
0.07914505153894424,
0.011951222084462643,
0.056155212223529816,
0.05039111152291298,
0.015479962341487408,
-0.007270364090800285,
-0.06902056187391281,
-0.012456129305064678,
0.014532702043652534,
-0.020366396754980087,
0.087492935359478,
-0.05058589577674866,
0.07093656808137894,
-0.03913695365190506,
-0.0788954421877861,
0.0007970593287609518,
-0.029746918007731438,
-0.025093743577599525,
0.00579577824100852,
0.05233854055404663,
-0.023972194641828537,
-0.013266335241496563,
0.025386331602931023,
-0.10900694131851196,
-0.021077901124954224,
0.014997473917901516,
0.09058204293251038,
0.02397165820002556,
0.1418885886669159,
0.047258321195840836,
-0.020223362371325493,
0.023321812972426414,
-0.007866502739489079,
-0.02665392868220806,
0.02961084060370922,
-0.03660627827048302,
-0.10681848227977753,
-0.04285656288266182,
0.047621600329875946,
-0.012731103226542473,
-0.021293722093105316,
-0.018854044377803802,
0.019976120442152023,
0.0373498797416687,
0.01073662843555212,
0.006074465811252594,
0.01860712096095085,
-0.025022832676768303,
0.0067314039915800095,
0.018042773008346558,
-0.06312356144189835,
-0.022297611460089684,
-0.05142177268862724,
0.053840409964323044,
-0.013322054408490658,
0.009848044253885746,
-0.03273993358016014,
-0.0717768445611,
-0.08368013054132462,
0.0006244869437068701,
0.033506352454423904,
0.12066423892974854,
-0.061940841376781464,
0.03375057876110077,
0.020268654450774193,
0.0951794907450676,
-0.027714768424630165,
0.006841685157269239,
-0.03926413133740425,
-0.056527137756347656,
0.04360458254814148,
-0.07212065905332565,
0.04060109332203865,
-0.07575620710849762,
-0.04719441756606102,
-0.005871517583727837,
-3.310462659555924e-8,
0.08217345923185349,
-0.058759644627571106,
0.03632810339331627,
-0.006907327566295862,
0.024030759930610657,
0.0037190932780504227,
-0.11106227338314056,
0.03506416827440262,
0.12285483628511429,
0.08937786519527435,
0.07561630010604858,
-0.06576050072908401,
-0.05811353772878647,
0.044665075838565826,
0.022309208288788795,
0.05605432018637657,
-0.014992799609899521,
0.08175525814294815,
-0.009000452235341072,
0.07521053403615952,
-0.08618966490030289,
-0.04309222474694252,
-0.009404590353369713,
0.04145832732319832,
0.06219889596104622,
0.030916651710867882,
0.00531579228118062,
-0.040967803448438644,
0.05541791021823883,
-0.11147569119930267,
0.025410426780581474,
-0.011474484577775002,
-0.07543614506721497,
0.010014012455940247,
-0.006610817275941372,
-0.007994799874722958,
0.005445387214422226,
0.01911364309489727,
-0.02372780442237854,
0.009979314170777798,
0.03311070054769516,
-0.08463447540998459,
-0.07929380238056183,
0.009807266294956207,
-0.04127005860209465,
-0.02718178555369377,
-0.017569303512573242,
0.03307889401912689,
-0.06427634507417679,
-0.07509240508079529,
-0.012996508739888668,
-0.0010710373753681779,
0.055550284683704376,
-0.031125957146286964,
0.07259376347064972,
0.045622412115335464,
0.07155955582857132,
-0.1031884104013443,
0.03142949193716049,
-0.015301876701414585,
0.05536471679806709,
-0.0008799377828836441,
0.13920657336711884,
0.004534399136900902
] |
PMID:30135434 | Using a phylogenetic analysis to compare the genes involved in virus entry, we observed that the HCMV-DB strain is close to the HCMV strain Merlin, the prototype HCMV strain. | [
-0.04422894865274429,
-0.0010020326590165496,
-0.03245474398136139,
-0.07218237221240997,
0.028796542435884476,
0.02959456294775009,
-0.05885540321469307,
-0.02578093484044075,
-0.02228466048836708,
-0.009705091826617718,
-0.0190325528383255,
-0.05431012436747551,
0.03396596014499664,
0.04501846060156822,
-0.02271321415901184,
-0.0890342965722084,
-0.06536451727151871,
-0.09971516579389572,
0.040477290749549866,
0.027307454496622086,
-0.06226677820086479,
0.037530992180109024,
0.05412480607628822,
0.037183456122875214,
-0.07582934945821762,
0.05128002539277077,
0.03476895019412041,
0.13051648437976837,
0.018258973956108093,
-0.06885164976119995,
-0.057387225329875946,
-0.010465654544532299,
0.03873243182897568,
0.014817764982581139,
-0.0859452486038208,
0.055184319615364075,
-0.059058625251054764,
0.003360370174050331,
0.004222663585096598,
-0.020849402993917465,
0.03101765364408493,
0.03694732487201691,
0.037628334015607834,
0.05752991884946823,
0.04991420730948448,
0.035218168050050735,
-0.04461228474974632,
-0.004785351920872927,
0.0629829689860344,
-0.00001724434878269676,
-0.04684107005596161,
0.05081508681178093,
-0.0037598037160933018,
0.051939841359853745,
-0.0825612023472786,
0.049216799437999725,
-0.039151664823293686,
-0.047267425805330276,
0.04143563285470009,
-0.002312330063432455,
-0.006243763491511345,
0.09882815927267075,
0.02438395284116268,
0.020159175619482994,
-0.03266577050089836,
-0.05239589884877205,
0.10943230986595154,
0.060547277331352234,
0.011595881544053555,
-0.0298157949000597,
-0.017597856000065804,
-0.025319963693618774,
-0.11314249783754349,
0.03592329099774361,
-0.06037619337439537,
0.05121806263923645,
0.015993330627679825,
-0.03738626092672348,
0.008892575278878212,
0.00288974167779088,
-0.043643590062856674,
0.035045623779296875,
0.053519949316978455,
0.06627138704061508,
-0.08993932604789734,
-0.00621434859931469,
-0.01561967097222805,
-0.024672873318195343,
0.004141024313867092,
0.07090357691049576,
-0.03284240514039993,
-0.07675709575414658,
0.05880676954984665,
0.036976225674152374,
-0.019553938880562782,
0.048588622361421585,
0.11834218353033066,
0.050895240157842636,
0.08791284263134003,
-0.01275019720196724,
-0.014172310009598732,
-0.07417802512645721,
-0.01939360983669758,
0.023210858926177025,
0.059258271008729935,
-0.003541391808539629,
-0.04891586676239967,
0.05342273414134979,
0.050958484411239624,
-0.02528613992035389,
0.04836307093501091,
0.05521199479699135,
0.01609022170305252,
-0.08690374344587326,
0.02327040396630764,
0.06443604081869125,
-0.021582743152976036,
-0.03071977198123932,
-0.04158100113272667,
0.020480044186115265,
-0.0015827663009986281,
-0.014049454592168331,
0.09507675468921661,
-0.035615090280771255,
-0.07349273562431335,
-0.07583506405353546,
-0.05517847090959549,
-1.7791307201076946e-33,
-0.0010887449607253075,
-0.06780122220516205,
0.04077460616827011,
0.0037306153681129217,
0.020209450274705887,
-0.013882223516702652,
0.009749189019203186,
0.11895751953125,
-0.07544700056314468,
-0.07762883603572845,
-0.07560469955205917,
-0.044698283076286316,
0.0208933986723423,
-0.00695369578897953,
-0.04770879074931145,
0.00848486926406622,
-0.06147707253694534,
-0.005630206782370806,
-0.1473349779844284,
0.022314080968499184,
-0.008633898571133614,
0.006195791531354189,
0.09162421524524689,
0.0039815036579966545,
0.08981595188379288,
-0.037881456315517426,
-0.05973026528954506,
-0.07478389889001846,
0.016759196296334267,
0.0016691428609192371,
-0.0004511296283453703,
0.010891323909163475,
-0.03379461169242859,
0.006075614597648382,
-0.0001831343543017283,
0.03293146565556526,
-0.08227014541625977,
-0.10288946330547333,
0.020256316289305687,
-0.0024249551352113485,
0.04076984152197838,
0.02517358399927616,
0.023477984592318535,
-0.06855635344982147,
-0.028835872188210487,
-0.01625172793865204,
-0.004818360321223736,
-0.017310593277215958,
-0.08173786103725433,
-0.023735662922263145,
0.0074824076145887375,
0.05028431490063667,
0.02951362542808056,
-0.05195482447743416,
-0.06933760643005371,
0.011753902770578861,
0.04001091793179512,
0.01859366148710251,
-0.001656971639022231,
0.04133610799908638,
0.04917348176240921,
0.07530251890420914,
0.016658009961247444,
0.07506269961595535,
0.030119119212031364,
-0.09612476825714111,
0.002009793883189559,
0.0518837608397007,
-0.020184431225061417,
0.07587612420320511,
-0.002534489380195737,
0.03471345081925392,
-0.02288411557674408,
-0.06493036448955536,
0.08910156041383743,
-0.05112890526652336,
-0.06443341076374054,
-0.10086867213249207,
0.01931091398000717,
-0.057558875530958176,
-0.009566638618707657,
0.009606829844415188,
0.11814257502555847,
-0.04482106864452362,
-0.07396865636110306,
-0.03159095719456673,
0.04581068083643913,
-0.05494896322488785,
-0.018571848049759865,
0.052987825125455856,
-0.025907600298523903,
0.04824043810367584,
0.04631686583161354,
-0.0658598393201828,
0.006744899787008762,
-1.1999145112766513e-33,
-0.008356649428606033,
-0.024587096646428108,
0.02008499577641487,
0.0067869932390749454,
-0.04866402968764305,
0.05443580076098442,
0.04336465522646904,
0.049960047006607056,
-0.028934014961123466,
0.0066369641572237015,
0.09022188931703568,
0.04659924656152725,
0.04038269445300102,
-0.01421540416777134,
-0.002008034847676754,
-0.019013147801160812,
0.009472949430346489,
0.08367110788822174,
-0.02324128895998001,
0.021160118281841278,
0.04754824936389923,
-0.02038571983575821,
-0.029933102428913116,
-0.06915368139743805,
0.04131330922245979,
-0.06309876590967178,
0.01889171451330185,
0.07393725216388702,
-0.006681963335722685,
0.0844033882021904,
-0.05342196300625801,
0.07067972421646118,
0.003277367213740945,
0.029833000153303146,
-0.006286511663347483,
0.00686905812472105,
0.026912488043308258,
-0.024472128599882126,
0.03788776323199272,
-0.022536752745509148,
0.03696298599243164,
0.03764600679278374,
-0.04992726072669029,
-0.016552140936255455,
-0.02389170229434967,
0.1054835394024849,
-0.013060315512120724,
0.109916090965271,
0.09132224321365356,
-0.022083384916186333,
0.047177594155073166,
0.0023737861774861813,
0.0009586561936885118,
0.04645359143614769,
-0.044614166021347046,
-0.025746461004018784,
-0.020238833501935005,
0.025327853858470917,
0.07130296528339386,
-0.00878551322966814,
-0.023977644741535187,
0.012296628206968307,
-0.002249227836728096,
-0.03580823540687561,
0.0024901877623051405,
0.0002778980997391045,
-0.0037186939734965563,
0.041700880974531174,
0.010952219367027283,
-0.139120951294899,
0.03977733850479126,
-0.012045089155435562,
0.06893516331911087,
-0.04813374578952789,
-0.012881356291472912,
-0.03853416442871094,
-0.02330884523689747,
-0.08466736227273941,
0.011764460243284702,
-0.04887140169739723,
0.1206018477678299,
-0.04138227924704552,
0.06974298506975174,
-0.026199128478765488,
0.04960613325238228,
-0.004660952836275101,
0.0014767165994271636,
-0.033716894686222076,
-0.09919454902410507,
0.048757705837488174,
-0.04307316988706589,
-0.010642367415130138,
-0.01279074139893055,
-0.08694487065076828,
-0.0076529476791620255,
-2.704042501022741e-8,
0.08553030341863632,
-0.0262130219489336,
0.0666985958814621,
0.0046422481536865234,
0.06358431279659271,
0.08569785207509995,
-0.07435468584299088,
0.004726886749267578,
0.0902273878455162,
0.06518151611089706,
0.07289110124111176,
-0.04903142526745796,
-0.020260745659470558,
0.006224905606359243,
-0.008922516368329525,
0.032005392014980316,
-0.09721697121858597,
0.07025281339883804,
-0.039347756654024124,
0.07481516152620316,
-0.03869252651929855,
0.011162449605762959,
-0.02147589437663555,
0.0439143069088459,
0.03944022208452225,
-0.02460755966603756,
-0.023536676540970802,
-0.03893033787608147,
0.06718865036964417,
-0.1292259693145752,
-0.0803004577755928,
0.03017636388540268,
-0.008149576373398304,
-0.027655871585011482,
-0.04538089409470558,
0.0076189544051885605,
-0.020455969497561455,
0.005973393097519875,
0.029011212289333344,
-0.004070996772497892,
0.060119710862636566,
-0.13208100199699402,
-0.03840533643960953,
-0.02148522436618805,
-0.006327784154564142,
-0.00250140018761158,
-0.023964595049619675,
-0.020751507952809334,
-0.056510668247938156,
-0.08166654407978058,
0.05656157806515694,
0.003877556649968028,
0.08781643956899643,
-0.041967377066612244,
-0.01949666254222393,
0.011422764509916306,
0.01750965043902397,
-0.10850512236356735,
0.03565632551908493,
-0.052195191383361816,
0.015875576063990593,
-0.03361999988555908,
0.15067610144615173,
-0.015656298026442528
] |
PMID:30135434 | HCMV-DB infects human mammary epithelial cells (HMECs) which in turn display a ER-/PR-/HER2- phenotype, commonly refered to as triple negative. | [
-0.01101556047797203,
-0.021868553012609482,
-0.06955860555171967,
-0.048112329095602036,
-0.0032883610110729933,
-0.003180960426107049,
0.037498053163290024,
0.056747276335954666,
0.04909096285700798,
0.016463596373796463,
0.02305503562092781,
-0.029303941875696182,
0.016159171238541603,
0.020747248083353043,
-0.01647810824215412,
0.08053004741668701,
-0.014973181299865246,
-0.013582604937255383,
0.006636787671595812,
0.0668969601392746,
-0.0361105352640152,
0.0076994383707642555,
0.05420224741101265,
0.05730116739869118,
-0.0566837303340435,
-0.029093312099575996,
-0.02442161552608013,
0.07630143314599991,
-0.012298965826630592,
-0.043748270720243454,
-0.022410936653614044,
-0.02461935207247734,
0.12026697397232056,
0.08812594413757324,
-0.038389839231967926,
-0.0028559300117194653,
-0.0024843704886734486,
0.014891582541167736,
-0.12758466601371765,
0.004456049297004938,
0.04912548139691353,
-0.05674494430422783,
-0.049911823123693466,
0.031684260815382004,
0.03715386614203453,
0.053547147661447525,
-0.08499159663915634,
-0.00323765492066741,
-0.009337657131254673,
0.03634016960859299,
0.07101591676473618,
-0.03922559320926666,
-0.024396279826760292,
0.07271292805671692,
-0.05348688364028931,
0.02260226011276245,
-0.05681328848004341,
0.03308439999818802,
0.01907414197921753,
-0.029783131554722786,
0.00012319641245994717,
0.030723202973604202,
0.04317499324679375,
0.020001204684376717,
0.090945765376091,
-0.0032690721563994884,
0.016696924343705177,
-0.013076487928628922,
0.0004802019102498889,
0.00008359086496056989,
-0.017069857567548752,
-0.08218036592006683,
-0.05065331235527992,
-0.0012653712183237076,
0.01399841159582138,
0.09140396118164062,
0.026005985215306282,
-0.043063655495643616,
0.015648137778043747,
0.013758813962340355,
0.013011567294597626,
0.03319314867258072,
0.012600269168615341,
0.0687689483165741,
0.013646198436617851,
-0.039559412747621536,
-0.06459856033325195,
-0.04815693944692612,
-0.04174179583787918,
0.00859909225255251,
-0.057623036205768585,
-0.06362801045179367,
-0.005980159621685743,
0.09873294085264206,
-0.02860248275101185,
0.03034190647304058,
-0.001505700871348381,
0.031575195491313934,
0.05065762251615524,
0.0007482419023290277,
-0.05104729160666466,
0.010386739857494831,
-0.10902108997106552,
-0.042262524366378784,
0.061239637434482574,
-0.03650585189461708,
0.012062904424965382,
-0.0027104769833385944,
-0.0047662099823355675,
-0.028482332825660706,
0.02982999011874199,
0.027465587481856346,
-0.0013073270674794912,
-0.07413715869188309,
0.05829271301627159,
0.05916866287589073,
-0.015711572021245956,
-0.017877129837870598,
-0.012022439390420914,
-0.1283920556306839,
-0.07940716296434402,
-0.0606716126203537,
0.040344417095184326,
-0.0776592418551445,
-0.06719018518924713,
-0.029130645096302032,
-0.02805987186729908,
-1.0200488145794714e-33,
-0.014191707596182823,
-0.04587214067578316,
0.1274253875017166,
-0.007779019419103861,
0.01030225120484829,
0.03564419597387314,
-0.030084094032645226,
-0.02290799468755722,
0.041587382555007935,
-0.06678454577922821,
-0.028225339949131012,
-0.040695544332265854,
0.036684706807136536,
0.034637268632650375,
-0.026027189567685127,
0.007849359884858131,
-0.06802095472812653,
-0.00532440934330225,
-0.0421200655400753,
0.04036654159426689,
0.026948601007461548,
0.028409181162714958,
0.03448408842086792,
-0.03645557165145874,
0.06457430124282837,
0.050543904304504395,
-0.052830278873443604,
0.001605861121788621,
0.07754503190517426,
0.014920352958142757,
-0.05373281240463257,
-0.022938959300518036,
-0.03501357510685921,
-0.010892900638282299,
-0.07187160849571228,
0.059007998555898666,
-0.09659972041845322,
-0.03287151828408241,
0.0007989034056663513,
0.06113962084054947,
-0.09598986059427261,
-0.03313812240958214,
0.047062914818525314,
-0.058248795568943024,
-0.0011598489945754409,
-0.045024361461400986,
-0.016412323340773582,
-0.02873809263110161,
-0.16609886288642883,
-0.06785173714160919,
-0.013788674026727676,
-0.003617358859628439,
-0.044539231806993484,
-0.03967577964067459,
-0.03463175892829895,
-0.008411729708313942,
-0.008161264471709728,
0.07053302228450775,
-0.008009555749595165,
0.02470887452363968,
0.025177372619509697,
0.03204989433288574,
0.016795633360743523,
0.036633480340242386,
-0.01258186623454094,
-0.034043386578559875,
-0.0606892853975296,
-0.04825694486498833,
-0.011699235066771507,
0.07531019300222397,
0.04725407436490059,
0.03741223365068436,
0.07037569582462311,
-0.040242258459329605,
0.03343959525227547,
-0.02922867052257061,
-0.015870384871959686,
0.01765459217131138,
0.04001433029770851,
-0.004012231715023518,
-0.026950601488351822,
-0.025411762297153473,
-0.0030727980192750692,
0.015604990534484386,
-0.012437624856829643,
-0.060347530990839005,
-0.0014819517964497209,
-0.060977306216955185,
-0.055886030197143555,
0.030626092106103897,
0.024816282093524933,
0.077939972281456,
0.022867968305945396,
-0.030241647735238075,
-0.00005922904165345244,
-2.6176582276652498e-33,
-0.01778123341500759,
0.010457126423716545,
-0.06048787757754326,
-0.03325454518198967,
0.030988456681370735,
0.04747887700796127,
0.021456006914377213,
0.04050728678703308,
-0.02510123699903488,
0.013012843206524849,
0.11770705133676529,
-0.04869538173079491,
-0.004881652072072029,
0.017135675996541977,
0.03325784206390381,
-0.032009802758693695,
0.004953477066010237,
0.012963835150003433,
0.005183412227779627,
0.04427257180213928,
0.058455921709537506,
0.0631142258644104,
0.0503971092402935,
0.06183766946196556,
0.0023041367530822754,
-0.04246516525745392,
-0.021230019629001617,
-0.003293303307145834,
-0.01291581429541111,
0.09460851550102234,
-0.04577434062957764,
0.14751151204109192,
-0.03319234773516655,
0.02713671326637268,
0.0053578815422952175,
-0.10488848388195038,
-0.022363439202308655,
-0.07691676169633865,
0.03696059435606003,
-0.07419583201408386,
0.006344178691506386,
0.0369836688041687,
-0.06764992326498032,
0.026369767263531685,
-0.0090415570884943,
0.16260956227779388,
0.005926202051341534,
0.11860952526330948,
0.12660051882266998,
-0.05336170271039009,
-0.05310089886188507,
0.012216132134199142,
-0.006226478144526482,
0.08375420421361923,
0.01982276327908039,
-0.03843909129500389,
-0.043439339846372604,
-0.04537877067923546,
0.04090014845132828,
0.019137106835842133,
-0.053012385964393616,
-0.03638383373618126,
-0.02598107047379017,
-0.044543106108903885,
-0.030863024294376373,
0.08205912262201309,
0.03633415699005127,
0.008669381961226463,
0.013476114720106125,
-0.04669295623898506,
0.08382058143615723,
0.06738454103469849,
-0.04664264991879463,
-0.06828318536281586,
-0.059243470430374146,
-0.10911480337381363,
-0.07919994741678238,
-0.04171682149171829,
0.054432883858680725,
-0.009739663451910019,
-0.03128884732723236,
-0.02168060652911663,
0.07945039868354797,
-0.004169021267443895,
0.09693357348442078,
-0.10811855643987656,
-0.062176886945962906,
0.05359344184398651,
-0.07360126823186874,
0.0811617523431778,
-0.0748036578297615,
0.022461827844381332,
-0.07238958775997162,
0.022510837763547897,
-0.05354819819331169,
-3.149083838138722e-8,
0.04142818599939346,
-0.06585804373025894,
0.05867772921919823,
-0.11342550069093704,
-0.011181987822055817,
-0.029943279922008514,
-0.16231314837932587,
0.05554208159446716,
0.1227661594748497,
0.050084348767995834,
0.008490738458931446,
0.0261242613196373,
-0.02717800997197628,
-0.057119086384773254,
0.053666893392801285,
0.0277545303106308,
0.041217200458049774,
0.06610983610153198,
-0.004681318998336792,
-0.030901722609996796,
-0.035601451992988586,
0.005344642326235771,
-0.02269674465060234,
0.007243165280669928,
0.07942566275596619,
0.05030316486954689,
0.03652563691139221,
-0.004281938541680574,
0.01686711795628071,
-0.09662146866321564,
0.0640895813703537,
0.0241906326264143,
0.018656747415661812,
0.03851290047168732,
-0.02543427050113678,
0.03912799432873726,
0.025743858888745308,
0.010725383646786213,
0.00007313738024095073,
-0.032362110912799835,
-0.05953831225633621,
-0.09254028648138046,
0.0005292802816256881,
0.008275815285742283,
-0.03981392830610275,
0.010200928896665573,
0.03337627649307251,
-0.009050058200955391,
-0.06064372882246971,
-0.04189661517739296,
-0.020938172936439514,
-0.031597286462783813,
0.10028861463069916,
0.019690455868840218,
-0.015964115038514137,
0.08293666690587997,
0.03976790979504585,
-0.1161573976278305,
0.06123913452029228,
-0.017927035689353943,
0.03654737025499344,
-0.02661430835723877,
0.1363142877817154,
0.0019993879832327366
] |
PMID:30135434 | The transcriptome of HCMV-DB-infected HMECs presents the characteristics of a pro-oncogenic cellular environment with upregulated expression of numerous oncogenes, enhanced activation of pro-survival genes, and upregulated markers of cell proliferation, stemcellness and epithelial mesenchymal transition (EMT) that was confirmed by enhanced cellular proliferation and tumorsphere formation in vitro. | [
-0.06130826845765114,
-0.040805745869874954,
-0.06587870419025421,
-0.07268879562616348,
0.11203153431415558,
0.009978161193430424,
0.0481521412730217,
0.07140407711267471,
0.03667145594954491,
0.04677040874958038,
-0.015921538695693016,
-0.0012716281926259398,
0.04723241925239563,
-0.008935180492699146,
-0.06974354386329651,
0.10527615249156952,
-0.06912065297365189,
0.051277317106723785,
0.006960752885788679,
-0.01591234654188156,
-0.03223561495542526,
0.011865477077662945,
0.08216720819473267,
0.005385615397244692,
0.0073277452029287815,
-0.030795780941843987,
0.027684738859534264,
0.10619308799505234,
0.006029621697962284,
-0.025367219001054764,
-0.01836702786386013,
-0.05323590338230133,
0.04792516306042671,
0.06168723851442337,
-0.03893918916583061,
0.0384640209376812,
0.008331614546477795,
0.043775878846645355,
-0.0785277932882309,
-0.005681548733264208,
0.048896756023168564,
-0.044739287346601486,
-0.03385644406080246,
0.024350639432668686,
0.03995009511709213,
-0.03406795114278793,
-0.025900984182953835,
-0.021890081465244293,
-0.017387203872203827,
0.0900164470076561,
0.059904590249061584,
-0.0016834863927215338,
-0.038717903196811676,
-0.004749680403620005,
-0.09362105280160904,
0.012830490246415138,
-0.04871136322617531,
0.0631163939833641,
0.08194319903850555,
-0.0630815252661705,
-0.020108293741941452,
-0.025609426200389862,
0.08951131254434586,
0.006627391558140516,
-0.05025899037718773,
-0.06719942390918732,
0.024031739681959152,
0.0590214841067791,
-0.07358340173959732,
-0.039696164429187775,
-0.034603431820869446,
-0.04828600212931633,
-0.04163305461406708,
0.021896351128816605,
-0.0415494479238987,
0.040279731154441833,
0.07805634289979935,
-0.01757708564400673,
0.026987997815012932,
0.0981280729174614,
-0.034585293382406235,
0.020732684060931206,
0.06430844962596893,
0.020428426563739777,
-0.05101292207837105,
0.005046205595135689,
-0.051008958369493484,
0.038094308227300644,
-0.007897960022091866,
0.05889374017715454,
-0.044529449194669724,
-0.050321850925683975,
0.03179951012134552,
0.0849202573299408,
0.039540186524391174,
0.02432350628077984,
0.07009457051753998,
0.01836305670440197,
0.08952657878398895,
-0.031022068113088608,
-0.10533666610717773,
-0.03797050192952156,
-0.07049015164375305,
-0.036013104021549225,
0.04029131680727005,
-0.06825848668813705,
-0.06129006668925285,
0.027778832241892815,
0.057263657450675964,
-0.015996843576431274,
0.05338577181100845,
-0.01126173697412014,
0.011372937820851803,
-0.025608522817492485,
0.03229419142007828,
0.09251856058835983,
-0.0359283909201622,
-0.05451611801981926,
0.00560953002423048,
-0.055544305592775345,
-0.006252245046198368,
-0.02399715781211853,
0.010244952514767647,
-0.007660117466002703,
-0.11760913580656052,
-0.01811300776898861,
0.05546913668513298,
1.995012278017123e-33,
-0.030819974839687347,
-0.06598862260580063,
0.030627310276031494,
0.04886757582426071,
-0.018724732100963593,
0.00904668029397726,
0.057573482394218445,
0.037218138575553894,
-0.04346618056297302,
-0.10144905000925064,
-0.026331156492233276,
-0.03661339730024338,
0.014045857824385166,
0.015025118365883827,
-0.045158978551626205,
-0.01062128134071827,
-0.032657917588949203,
-0.07244541496038437,
-0.10479249805212021,
0.004644796717911959,
-0.029936721548438072,
-0.008778881281614304,
0.058396562933921814,
-0.02694283053278923,
-0.01013099867850542,
-0.052801698446273804,
-0.03325643017888069,
0.02699858695268631,
0.04370652884244919,
-0.01620367355644703,
-0.06602893769741058,
-0.00752491457387805,
0.04984574019908905,
-0.03896353021264076,
-0.04894560948014259,
0.11421898752450943,
-0.08930587023496628,
-0.010523230768740177,
0.031675588339567184,
0.016150351613759995,
-0.0003457510028965771,
-0.010518963448703289,
-0.02054769918322563,
-0.07839535921812057,
0.04008389636874199,
-0.05736067146062851,
-0.04454910382628441,
0.011422183364629745,
-0.08253788203001022,
-0.026749959215521812,
0.012716760858893394,
0.03150365874171257,
-0.03421682491898537,
-0.04532494768500328,
-0.02900116518139839,
-0.022436290979385376,
-0.11433883011341095,
0.0477580688893795,
-0.06047094613313675,
0.0009652089793235064,
-0.02316778339445591,
-0.027274323627352715,
0.026343999430537224,
0.14220716059207916,
-0.007618669420480728,
-0.07601474970579147,
-0.048999834805727005,
0.010334279388189316,
-0.06797777861356735,
0.1054486408829689,
0.08372030407190323,
0.053333282470703125,
0.03899169713258743,
-0.07545667141675949,
-0.005453555379062891,
-0.022582171484827995,
-0.022618237882852554,
0.04774554818868637,
-0.014880716800689697,
0.08757133781909943,
0.04805842041969299,
0.08781711012125015,
-0.013489632867276669,
-0.01485628355294466,
0.0442543663084507,
-0.06144681200385094,
0.011118660680949688,
-0.010879677720367908,
-0.05210200697183609,
0.0406922772526741,
-0.0024351764004677534,
0.006852453574538231,
-0.015636609867215157,
-0.025768930092453957,
-0.012530511245131493,
-4.459982789389181e-33,
-0.005490120034664869,
-0.012164153158664703,
0.01773528754711151,
-0.008873502723872662,
-0.032101720571517944,
0.11396060138940811,
0.041480064392089844,
0.05327793210744858,
-0.09032370895147324,
-0.010489339008927345,
0.03940749913454056,
-0.005328012630343437,
-0.03469083458185196,
-0.044855549931526184,
-0.028409387916326523,
-0.12927241623401642,
-0.047671299427747726,
0.05847178027033806,
-0.021326905116438866,
0.09645911306142807,
0.053395844995975494,
0.0268240999430418,
-0.034996699541807175,
0.00575552973896265,
-0.06514373421669006,
-0.047362182289361954,
-0.04992999508976936,
0.04615152254700661,
-0.06137710064649582,
0.09635919332504272,
0.016244856640696526,
0.10551346093416214,
-0.019407181069254875,
0.029146376997232437,
0.02998398058116436,
-0.0031998970080167055,
0.05539718642830849,
-0.06639707833528519,
0.04261169582605362,
-0.011380186304450035,
0.013408088125288486,
-0.0239156112074852,
-0.08509582281112671,
-0.005898674950003624,
0.0039446246810257435,
0.16995437443256378,
-0.029031023383140564,
0.15072068572044373,
0.08427457511425018,
-0.04436192661523819,
-0.03743548318743706,
0.0036902406718581915,
-0.006684014108031988,
0.004454562906175852,
0.0020699207670986652,
0.006533545907586813,
-0.04259881749749184,
-0.00962372962385416,
-0.016187872737646103,
-0.04372036084532738,
-0.04473716393113136,
-0.03609412908554077,
0.005432596895843744,
0.007713634055107832,
0.028824226930737495,
0.05442525073885918,
0.021798068657517433,
0.024003891274333,
-0.0056655933149158955,
-0.026714669540524483,
0.006184379104524851,
0.014302083291113377,
-0.08114543557167053,
-0.09625773876905441,
-0.027311239391565323,
-0.09501424431800842,
-0.016434043645858765,
-0.0260623749345541,
0.04841954633593559,
0.01555187813937664,
-0.01830766350030899,
-0.023768603801727295,
0.029241612181067467,
-0.05544780194759369,
0.13444502651691437,
-0.00230079866014421,
-0.05821226164698601,
0.053279146552085876,
-0.04063921794295311,
0.08161996304988861,
-0.06376476585865021,
-0.020674489438533783,
-0.06483574956655502,
-0.023842211812734604,
-0.07339664548635483,
-4.027960542885012e-8,
0.06717050820589066,
-0.04737720265984535,
0.021794816479086876,
-0.04913740232586861,
0.003316605230793357,
0.035004872828722,
-0.08233578503131866,
0.020184671506285667,
0.12569785118103027,
0.05485915020108223,
0.04958656057715416,
-0.007886023260653019,
-0.008796432055532932,
-0.04392986372113228,
0.037987351417541504,
0.034618690609931946,
-0.016107594594359398,
0.06658186763525009,
0.01077633909881115,
0.04486621916294098,
-0.07397402822971344,
0.0277007594704628,
0.024754449725151062,
0.056532688438892365,
0.0730016753077507,
-0.03002488613128662,
0.022465258836746216,
0.03903351351618767,
0.03377138450741768,
-0.06257733702659607,
0.010693604126572609,
-0.01972990296781063,
0.012411832809448242,
-0.01407031249254942,
-0.06649470329284668,
-0.015243679285049438,
0.04945475980639458,
-0.026487817987799644,
0.09187990427017212,
0.02567809633910656,
0.03898707032203674,
-0.051974501460790634,
-0.006772191263735294,
-0.03375113010406494,
-0.0754234567284584,
0.04882623255252838,
-0.05820311978459358,
0.011993937194347382,
-0.048786528408527374,
-0.04660112038254738,
-0.04846401512622833,
-0.03655296191573143,
0.05564454570412636,
-0.03731502965092659,
-0.003331488464027643,
0.05298034846782684,
0.07355580478906631,
-0.044472239911556244,
0.08410796523094177,
-0.038026612251996994,
-0.02857593633234501,
0.018126843497157097,
0.1138959527015686,
-0.010821308009326458
] |
PMID:30135434 | Taken together our data indicate that some clinical isolates could be well adapted to the mammary tissue environment, as it is the case for the HCMV-DB strain. | [
-0.008052744902670383,
-0.05011949688196182,
-0.03163168951869011,
0.010452480986714363,
0.0585157684981823,
0.017481278628110886,
-0.07360634207725525,
0.04413305222988129,
-0.05709017813205719,
-0.008545203134417534,
-0.015817299485206604,
-0.0055871508084237576,
0.014528656378388405,
0.12272873520851135,
-0.0023531154729425907,
0.022269397974014282,
-0.004894932731986046,
-0.029291508719325066,
0.08724388480186462,
0.09238854795694351,
-0.057739656418561935,
0.06036694347858429,
0.011368011124432087,
0.05744311213493347,
-0.040093280375003815,
-0.020234214141964912,
-0.026279345154762268,
0.08492286503314972,
-0.03300292789936066,
-0.049081142991781235,
-0.05088694766163826,
-0.05209890753030777,
0.08014523237943649,
0.025616582483053207,
-0.03542137145996094,
-0.008067488670349121,
-0.008748792111873627,
0.036821555346250534,
-0.09120269864797592,
0.02219487354159355,
0.053601883351802826,
0.02516791597008705,
0.024205632507801056,
-0.0033397069200873375,
0.07417751103639603,
0.052892304956912994,
-0.05492621287703514,
0.0027597432490438223,
0.011328679509460926,
0.061900243163108826,
-0.019565965980291367,
-0.06021769344806671,
-0.0062185414135456085,
0.07441556453704834,
-0.034308839589357376,
-0.017840560525655746,
-0.03713582456111908,
-0.03241664171218872,
-0.0018073428655043244,
-0.034966614097356796,
0.05061735957860947,
0.04939335212111473,
0.06843835860490799,
0.059756938368082047,
0.024061400443315506,
-0.05373355746269226,
0.045963313430547714,
0.0931510403752327,
0.053191959857940674,
0.01394402515143156,
-0.0053995088674128056,
-0.0080474354326725,
-0.017432551831007004,
0.019037727266550064,
-0.04395807534456253,
0.048537418246269226,
0.034118399024009705,
-0.054562896490097046,
0.09151220321655273,
0.0710948184132576,
-0.055724527686834335,
0.01235862635076046,
-0.005046178121119738,
-0.01869397982954979,
-0.06423771381378174,
-0.05368831381201744,
0.00010792319517349824,
-0.01762363128364086,
-0.06279682368040085,
-0.03302605077624321,
0.01618269458413124,
-0.02063378505408764,
0.008238479495048523,
0.05550845339894295,
0.026108520105481148,
0.04991530254483223,
0.006394346710294485,
-0.005662007723003626,
0.08034636825323105,
-0.04481115564703941,
-0.07328685373067856,
-0.038439229130744934,
-0.0452897772192955,
-0.01238448079675436,
0.04193433001637459,
-0.06381770968437195,
-0.0016604546690359712,
-0.03454577922821045,
0.007116842083632946,
0.05257291719317436,
0.02953697368502617,
0.09330295771360397,
0.004261489026248455,
-0.08383242040872574,
0.06821142882108688,
0.004165830090641975,
0.030043883249163628,
-0.09536966681480408,
-0.06334082782268524,
-0.001976441126316786,
-0.03349969908595085,
-0.08964712917804718,
0.11298473179340363,
-0.09177921712398529,
0.04386698827147484,
-0.027257265523076057,
0.007793290540575981,
-2.0677292769139514e-33,
0.011841107159852982,
-0.07040723413228989,
0.11398441344499588,
0.01976715214550495,
0.07358040660619736,
0.028673205524683,
-0.026652667671442032,
-0.05070851743221283,
-0.00574878603219986,
-0.074386365711689,
-0.0272376611828804,
-0.009807893075048923,
0.009936257265508175,
-0.022439749911427498,
0.016144637018442154,
0.021709153428673744,
-0.026977170258760452,
0.019861256703734398,
-0.08385657519102097,
0.032953932881355286,
-0.027183694764971733,
-0.018339239060878754,
0.04617120325565338,
0.030243225395679474,
0.0318116620182991,
0.00885352399200201,
-0.046232931315898895,
-0.023840254172682762,
0.03131750226020813,
-0.0015097439754754305,
-0.05661286786198616,
-0.07999689131975174,
-0.019787419587373734,
-0.0030394792556762695,
-0.0284673273563385,
0.06737068295478821,
-0.09430652856826782,
-0.042858850210905075,
0.009432689286768436,
0.043897245079278946,
0.010985608212649822,
-0.03322076052427292,
0.1433776319026947,
-0.05016464740037918,
0.030270438641309738,
0.026511788368225098,
-0.07237324118614197,
-0.014119614847004414,
-0.10414136946201324,
-0.11142154037952423,
0.017378415912389755,
0.0046740323305130005,
-0.0515127070248127,
-0.14845715463161469,
-0.009259594604372978,
0.0010792979737743735,
-0.03842098265886307,
0.019545279443264008,
0.022036168724298477,
0.037906844168901443,
0.021214811131358147,
-0.037647027522325516,
0.06706029921770096,
0.04057734087109566,
-0.015209595672786236,
-0.0592196062207222,
-0.083114393055439,
-0.03138982504606247,
-0.04549054428935051,
0.07625395059585571,
-0.006651975680142641,
-0.032675646245479584,
-0.02159249782562256,
-0.06270557641983032,
0.03629134222865105,
0.028609594330191612,
0.005140447523444891,
0.006908383220434189,
0.010372464545071125,
-0.06271952390670776,
-0.05337173864245415,
0.0030722804367542267,
-0.044572047889232635,
0.10691183805465698,
-0.02377508021891117,
-0.01615309901535511,
-0.027434177696704865,
-0.004953461233526468,
0.02898990549147129,
0.010784026235342026,
0.02121433988213539,
0.05970090255141258,
0.03414350375533104,
-0.06525959074497223,
0.021472806110978127,
-1.8679854197313897e-33,
-0.010196319781243801,
0.000349135953001678,
-0.003383746137842536,
-0.0359325110912323,
0.041515592485666275,
0.07692179083824158,
0.00887240283191204,
0.11704207211732864,
-0.0035405403468757868,
0.010985669679939747,
-0.00637571606785059,
-0.060365691781044006,
-0.04729125276207924,
-0.0035100835375487804,
-0.05847180634737015,
0.07566840946674347,
-0.007830656133592129,
0.02727045863866806,
-0.021785086020827293,
0.051965177059173584,
0.02016213908791542,
0.04489382728934288,
0.03348661586642265,
-0.04107083007693291,
0.017269590869545937,
0.009467477910220623,
-0.10764608532190323,
-0.004695327021181583,
-0.030052613466978073,
0.06072951480746269,
-0.05201083421707153,
0.024219920858740807,
-0.04755628481507301,
-0.015509801916778088,
-0.0031944718211889267,
-0.01265686098486185,
-0.020691098645329475,
-0.049208447337150574,
0.061655767261981964,
-0.04592201113700867,
0.0597367137670517,
0.0370648056268692,
-0.08324944227933884,
-0.0341174341738224,
0.004570427816361189,
0.1372302770614624,
0.058128535747528076,
0.009115919470787048,
0.07434873282909393,
-0.020352721214294434,
-0.019546639174222946,
-0.04206233099102974,
-0.011630013585090637,
0.02295644022524357,
-0.03037414886057377,
-0.03993396461009979,
0.0031563525553792715,
0.00981754157692194,
-0.01770223118364811,
-0.0065611288882792,
-0.07463879138231277,
0.014876015484333038,
-0.08607872575521469,
-0.057655591517686844,
-0.03702722489833832,
0.06642003357410431,
-0.00810889434069395,
-0.004237697459757328,
-0.05766885355114937,
-0.07469416409730911,
0.006442075129598379,
-0.003408371703699231,
0.013259613886475563,
0.03503681719303131,
-0.008370398543775082,
-0.052736736834049225,
-0.046586934477090836,
-0.10327303409576416,
-0.01723415218293667,
0.029422737658023834,
0.04913269728422165,
-0.0671565979719162,
0.054325781762599945,
-0.019082695245742798,
0.12040236592292786,
-0.046275656670331955,
0.004044597037136555,
-0.0896352231502533,
-0.053787145763635635,
0.02923399582505226,
-0.09597233682870865,
0.01171165518462658,
-0.06816460937261581,
-0.018748948350548744,
-0.03528020158410072,
-3.218159605467008e-8,
0.02931300364434719,
-0.04518973082304001,
0.02248682640492916,
-0.11107246577739716,
0.007487346883863211,
-0.035156916826963425,
-0.146508127450943,
-0.010407724417746067,
0.13889358937740326,
0.09358017891645432,
-0.01321395207196474,
-0.020116375759243965,
-0.003476114943623543,
0.03387832269072533,
0.02022594027221203,
0.034951478242874146,
-0.024928364902734756,
0.055109187960624695,
-0.05976627767086029,
0.009681296534836292,
-0.06620415300130844,
0.009107166901230812,
-0.03805330768227577,
0.11600378155708313,
0.07144853472709656,
0.06388814747333527,
0.0031668643932789564,
-0.005916912574321032,
0.03148918226361275,
-0.04016141593456268,
0.05075788497924805,
0.04857918620109558,
-0.023476557806134224,
0.10552097856998444,
-0.0503280907869339,
0.03227533400058746,
0.03581901267170906,
-0.029931699857115746,
-0.04116859659552574,
0.03643922135233879,
-0.012413355521857738,
-0.13500088453292847,
0.0008977637626230717,
0.008639984764158726,
-0.03948953002691269,
-0.06670740991830826,
-0.022914355620741844,
-0.01667976938188076,
-0.031456951051950455,
0.01343591883778572,
0.010688756592571735,
-0.07109857350587845,
0.06045102700591087,
0.05459566041827202,
0.05748780816793442,
0.05645511671900749,
0.0663132295012474,
-0.10306565463542938,
0.0507732629776001,
0.006310438271611929,
0.018877148628234863,
-0.03843674808740616,
0.18258321285247803,
0.020543713122606277
] |
PMID:30135434 | This could influence the viral fitness, ultimately leading to breast cancer development. | [
0.009222965687513351,
-0.04711416736245155,
-0.08174031227827072,
0.03638600930571556,
0.05167493596673012,
-0.007881343364715576,
-0.018291041254997253,
-0.009487009607255459,
-0.05332779884338379,
-0.005471123848110437,
-0.04510152339935303,
0.06774335354566574,
0.011025262996554375,
0.02992938458919525,
0.014912637881934643,
0.04859068617224693,
-0.06973840296268463,
0.049213957041502,
-0.040863100439310074,
0.030226876959204674,
-0.018122034147381783,
-0.028297122567892075,
0.0974700003862381,
0.07432308048009872,
-0.05471491441130638,
-0.03595577925443649,
-0.02079921029508114,
0.08417587727308273,
-0.005603499244898558,
-0.019823500886559486,
0.0162370465695858,
-0.02990168146789074,
0.023047009482979774,
0.04721973091363907,
-0.11537078022956848,
0.0031380753498524427,
0.05275339633226395,
0.053416259586811066,
-0.08432300388813019,
0.024756111204624176,
0.012935126200318336,
-0.039020199328660965,
-0.003833252936601639,
0.08068341016769409,
0.06659696996212006,
-0.03879473730921745,
-0.04490097612142563,
0.012593326158821583,
0.0028849889058619738,
0.028853490948677063,
-0.033601026982069016,
-0.09030016511678696,
-0.04186528921127319,
-0.023519324138760567,
0.06336184591054916,
0.019049758091568947,
-0.05967967212200165,
-0.01026940904557705,
0.013333919458091259,
0.005664864555001259,
0.033778116106987,
-0.023896854370832443,
0.03006911277770996,
0.02117067575454712,
0.10307863354682922,
-0.016683237627148628,
0.004546019248664379,
0.09831845760345459,
-0.02836315520107746,
0.060514260083436966,
0.051868047565221786,
-0.014707337133586407,
-0.0917675644159317,
0.09281063824892044,
0.0318194255232811,
0.0810183510184288,
0.08899928629398346,
0.01235168520361185,
0.06644336879253387,
0.08392668515443802,
-0.06629454344511032,
-0.010624630376696587,
0.057065676897764206,
0.0685369223356247,
-0.09325908869504929,
-0.04667619988322258,
0.022273315116763115,
-0.12394236773252487,
-0.028615375980734825,
0.07215585559606552,
-0.01781933382153511,
0.01484684832394123,
-0.06967524439096451,
0.03729896619915962,
-0.07727904617786407,
0.07173806428909302,
-0.06438282132148743,
-0.05243588984012604,
-0.01745782606303692,
-0.030580058693885803,
-0.030951647087931633,
-0.05351203307509422,
0.0036052654031664133,
0.06182852014899254,
0.039059702306985855,
-0.0478123277425766,
0.030070295557379723,
-0.030858319252729416,
-0.01722775027155876,
0.05312420427799225,
0.03840319439768791,
0.026346774771809578,
0.020917566493153572,
0.007898956537246704,
0.04447496682405472,
0.08504698425531387,
-0.04747318848967552,
-0.08740195631980896,
-0.05623537302017212,
-0.026662342250347137,
-0.03426623344421387,
-0.060374267399311066,
0.0447767898440361,
-0.05274005979299545,
-0.026568064466118813,
-0.03950740769505501,
-0.020442651584744453,
-3.9889115098208115e-33,
0.02933868207037449,
-0.0547047033905983,
0.12075886875391006,
0.1437668800354004,
0.06786772608757019,
-0.007313092704862356,
-0.006265670992434025,
-0.07214038074016571,
-0.02641925774514675,
-0.07500895857810974,
-0.04245978593826294,
-0.009230323135852814,
0.05493198707699776,
0.042395833879709244,
0.01661710813641548,
-0.01585000939667225,
-0.02646910399198532,
0.04874160513281822,
-0.0872611477971077,
0.02640296332538128,
0.0511731281876564,
-0.049132056534290314,
-0.009990059770643711,
0.014702401123940945,
0.005449479445815086,
0.023465769365429878,
-0.060186177492141724,
0.046119797974824905,
0.002498963614925742,
-0.00721432501450181,
-0.0656716376543045,
-0.01117226667702198,
-0.03394904360175133,
0.0018666904652491212,
-0.04045906290411949,
0.042587585747241974,
0.038201481103897095,
-0.02313823252916336,
0.0720839723944664,
0.047657545655965805,
0.10438799858093262,
-0.054153017699718475,
0.054196394979953766,
-0.05139853432774544,
0.031550824642181396,
0.02255278266966343,
0.001426680013537407,
-0.06947620213031769,
-0.06895296275615692,
-0.028195485472679138,
0.03053811565041542,
-0.00338418735191226,
-0.03313163295388222,
-0.0018199015175923705,
-0.01948573626577854,
0.02001200057566166,
-0.07746892422437668,
0.0421111099421978,
-0.05031212419271469,
-0.03833691403269768,
0.034408606588840485,
-0.041460901498794556,
0.011627438478171825,
0.07254082709550858,
0.007178476545959711,
-0.012032423168420792,
0.03016100637614727,
-0.08312813937664032,
-0.01081544253975153,
0.118658646941185,
0.04830193147063255,
-0.09177814424037933,
-0.049509529024362564,
-0.09618686139583588,
0.04452972859144211,
0.04481780156493187,
-0.056711938232183456,
-0.02031690999865532,
0.03603869676589966,
0.06774748116731644,
-0.0491173192858696,
-0.014459215104579926,
-0.05549430474638939,
0.07345135509967804,
-0.011093360371887684,
-0.06468837708234787,
0.027683477848768234,
-0.0883120596408844,
0.03717125207185745,
-0.011536913923919201,
0.029481379315257072,
0.0033718086779117584,
0.03192916512489319,
-0.0009433927480131388,
-0.04479021951556206,
1.081314386282879e-33,
-0.04340755194425583,
-0.051709841936826706,
0.036432500928640366,
-0.03424181044101715,
0.08687606453895569,
0.048527687788009644,
0.046810589730739594,
-0.06310798972845078,
0.02932550385594368,
0.027735155075788498,
0.03270472213625908,
-0.06938967853784561,
-0.0900922641158104,
-0.02281465381383896,
-0.021305248141288757,
-0.016449205577373505,
0.05859052389860153,
0.025596901774406433,
-0.023626111447811127,
-0.003947779536247253,
0.03367585316300392,
0.05256670340895653,
0.0055868919007480145,
-0.01198522001504898,
-0.01829591952264309,
0.01997298002243042,
-0.0056714629754424095,
0.03001178801059723,
-0.010481550358235836,
0.04394552484154701,
-0.005457128398120403,
0.08222024887800217,
-0.05177735164761543,
0.05153844505548477,
0.009164786897599697,
0.045112721621990204,
0.004647678229957819,
-0.04429532587528229,
0.04417312517762184,
-0.09151779860258102,
0.02978258766233921,
0.08334880322217941,
-0.027009181678295135,
-0.03088173270225525,
0.026646114885807037,
0.011830929666757584,
0.09426720440387726,
0.07542579621076584,
0.03724062070250511,
0.01751064881682396,
0.05690170079469681,
-0.020524803549051285,
-0.004278811626136303,
0.03489658981561661,
-0.05541931092739105,
0.0018107236828655005,
0.009246882051229477,
0.0013734985841438174,
0.08842533826828003,
0.0480571873486042,
-0.1079416573047638,
-0.0223785862326622,
-0.09626121819019318,
-0.06230231374502182,
-0.03124159201979637,
0.08230032026767731,
0.00805485900491476,
0.01569719985127449,
0.013037359341979027,
-0.0894698053598404,
0.0680050253868103,
0.02475496381521225,
-0.039868518710136414,
0.042471472173929214,
-0.14543619751930237,
-0.0378619059920311,
0.016576075926423073,
-0.03013761341571808,
-0.01478121243417263,
-0.014075354672968388,
-0.12172868102788925,
-0.02302013896405697,
0.014153590425848961,
-0.09525119513273239,
0.035165321081876755,
-0.01893063448369503,
-0.05389877408742905,
0.02771914191544056,
-0.043562643229961395,
0.04237600788474083,
-0.08689400553703308,
-0.07030541449785233,
-0.05811644718050957,
-0.010813476517796516,
-0.06951648741960526,
-1.9674072149200583e-8,
0.008346442133188248,
-0.012856454588472843,
0.002326828194782138,
-0.022047484293580055,
0.04408516362309456,
0.07094601541757584,
-0.04946209862828255,
0.037817299365997314,
0.11700347065925598,
0.026767389848828316,
0.011887989938259125,
0.08313687890768051,
0.061319079250097275,
0.029439566656947136,
0.04477258026599884,
0.012824677862226963,
-0.016318989917635918,
0.022594524547457695,
-0.07124749571084976,
-0.044376082718372345,
0.0036082540173083544,
-0.024245688691735268,
-0.07134868949651718,
0.08793645352125168,
-0.07130897045135498,
-0.02579149231314659,
-0.04513542354106903,
0.050662893801927567,
0.05908055976033211,
-0.06935292482376099,
0.0541703961789608,
0.002480623545125127,
0.07852166891098022,
0.05043039098381996,
-0.022285496816039085,
0.048682183027267456,
0.017026469111442566,
-0.07860542088747025,
0.01953386515378952,
0.04786000773310661,
-0.006065061315894127,
-0.06286023557186127,
0.05277762562036514,
0.042768437415361404,
-0.10553151369094849,
-0.050108570605516434,
-0.03272769972681999,
0.020703166723251343,
0.02766985446214676,
-0.052692022174596786,
0.015059471130371094,
-0.028262242674827576,
0.0019281016429886222,
-0.035787612199783325,
-0.041655294597148895,
0.075420081615448,
-0.040761686861515045,
-0.02488744631409645,
0.057790447026491165,
0.0281333290040493,
0.02172795496881008,
-0.07044901698827744,
0.12485290318727493,
-0.01910119690001011
] |
PMID:33085037 | Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors (NETs). | [
-0.014005238190293312,
-0.038343384861946106,
-0.11242226511240005,
0.031100690364837646,
0.014325656928122044,
0.11014970391988754,
0.015446383506059647,
0.0851115733385086,
0.0470757782459259,
-0.08303552120923996,
0.022506536915898323,
0.03234555572271347,
-0.025197505950927734,
0.013090969994664192,
0.007634845096617937,
-0.03353220969438553,
-0.02579367905855179,
0.021532589569687843,
0.12494491785764694,
-0.018052807077765465,
-0.04396192729473114,
0.017773719504475594,
0.03406687080860138,
0.04076074808835983,
0.016927888616919518,
-0.006401080638170242,
-0.013353109359741211,
-0.02293093502521515,
-0.09207869321107864,
0.007643269840627909,
-0.010940461419522762,
-0.0462404303252697,
-0.11021753400564194,
0.0196684617549181,
-0.031627312302589417,
-0.025444665923714638,
-0.043748609721660614,
-0.044860485941171646,
-0.07350250333547592,
0.019958069548010826,
0.02725365199148655,
-0.03455366939306259,
-0.033582158386707306,
0.024736113846302032,
0.03782742843031883,
-0.04760356619954109,
-0.08965446799993515,
-0.09065736830234528,
-0.018564607948064804,
0.07045258581638336,
0.008662180975079536,
-0.005351612810045481,
-0.019931836053729057,
0.09208164364099503,
0.05113402009010315,
0.029924772679805756,
-0.025857148692011833,
0.019203830510377884,
-0.013590767979621887,
-0.014309912919998169,
-0.018577832728624344,
-0.06044847518205643,
0.04596560448408127,
-0.046984679996967316,
0.15064652264118195,
0.047107283025979996,
-0.005933847278356552,
-0.01458031591027975,
-0.0445469506084919,
0.01863975264132023,
0.01677124761044979,
0.021592147648334503,
-0.005614106543362141,
0.126241996884346,
0.019653242081403732,
-0.04809201881289482,
-0.054474037140607834,
0.06212068349123001,
0.017309483140707016,
-0.000805425108410418,
0.07577382028102875,
0.061939120292663574,
0.015375145711004734,
0.08765750378370285,
-0.029513899236917496,
-0.002887389389798045,
-0.017703479155898094,
0.05806927755475044,
-0.015565620735287666,
0.11592736840248108,
0.03711811080574989,
-0.013039624318480492,
-0.0663110539317131,
-0.07262037694454193,
-0.06413103640079498,
-0.08277279883623123,
-0.05442234128713608,
0.035304151475429535,
-0.02455988898873329,
-0.10203409940004349,
-0.01670076511800289,
-0.007669616024941206,
-0.04567430540919304,
0.009669115766882896,
0.04553848132491112,
0.0389358215034008,
-0.04634469747543335,
-0.056409988552331924,
0.03150204196572304,
-0.04670532047748566,
-0.06379029154777527,
-0.0882062166929245,
0.03432706743478775,
0.006132465321570635,
-0.0059210448525846004,
0.08336460590362549,
-0.04555051028728485,
0.06998437643051147,
0.022294923663139343,
-0.04014913737773895,
-0.002165664918720722,
-0.008145543746650219,
-0.014818686060607433,
0.07001068443059921,
0.04032960906624794,
0.02181423082947731,
-0.1355244666337967,
7.572463435487654e-34,
0.10907819122076035,
-0.00582949398085475,
0.012747449800372124,
0.013228981755673885,
-0.05841716751456261,
0.004983578342944384,
0.05411558598279953,
-0.04371270909905434,
0.012799733318388462,
-0.024198906496167183,
-0.06898186355829239,
-0.0635671615600586,
0.0005986416945233941,
0.05592736974358559,
0.008868388831615448,
-0.07686060667037964,
-0.03409291058778763,
0.0031883292831480503,
0.04748008772730827,
-0.13530664145946503,
-0.005964451935142279,
0.12897872924804688,
0.006878770422190428,
-0.018493352457880974,
0.020388303324580193,
-0.03314076364040375,
-0.06266790628433228,
0.1067626103758812,
0.009211813099682331,
-0.0023786481469869614,
-0.020695555955171585,
0.025549527257680893,
-0.0007705693715251982,
0.04599342122673988,
0.0843503549695015,
-0.05647963285446167,
0.04516102373600006,
-0.055272284895181656,
0.0515751987695694,
0.020680643618106842,
0.10655377060174942,
-0.015124700032174587,
-0.039963219314813614,
0.016559697687625885,
0.033047210425138474,
-0.04648715630173683,
-0.015972420573234558,
0.023815706372261047,
0.034251850098371506,
0.05517839640378952,
-0.0004357736324891448,
-0.007607598323374987,
-0.035506471991539,
0.025709107518196106,
-0.042908284813165665,
0.042298443615436554,
-0.07568904757499695,
-0.0027527378406375647,
-0.03481823951005936,
0.05036497116088867,
-0.05315421149134636,
-0.09860356152057648,
0.0380403958261013,
-0.01716076023876667,
0.026796890422701836,
0.04934857785701752,
-0.06196042150259018,
-0.09277050197124481,
-0.04653993621468544,
0.0016635371139273047,
-0.006591444835066795,
-0.002101774560287595,
0.07840412110090256,
-0.014280839823186398,
-0.030565360561013222,
0.046754542738199234,
-0.03821394592523575,
0.11251141130924225,
-0.041449397802352905,
0.014232369139790535,
-0.04011773690581322,
-0.022800758481025696,
-0.11656924337148666,
0.012268060818314552,
0.004293006844818592,
-0.043378736823797226,
0.05967976525425911,
-0.10545066744089127,
-0.03269065171480179,
0.011512302793562412,
0.010413933545351028,
-0.04793088138103485,
-0.0031821546144783497,
0.007858816534280777,
-0.008395140990614891,
-2.954832619151299e-33,
-0.011147159151732922,
-0.01194005273282528,
0.04931746795773506,
0.009212968870997429,
-0.07040024548768997,
0.05241144075989723,
0.027841780334711075,
-0.03683033213019371,
0.030519811436533928,
0.0939011499285698,
0.050586480647325516,
0.045462142676115036,
-0.026323147118091583,
-0.06738875061273575,
-0.006383769679814577,
-0.023991994559764862,
-0.02110130712389946,
0.0036614476703107357,
0.014978611841797829,
-0.05898066982626915,
-0.0059803747572004795,
0.013287251815199852,
-0.0750928446650505,
0.10128017514944077,
0.0069443718530237675,
0.05524579435586929,
0.041481003165245056,
0.0021859421394765377,
-0.045145608484745026,
0.040021345019340515,
-0.025228170678019524,
0.020461635664105415,
-0.0600251778960228,
-0.029447216540575027,
0.02323211543262005,
-0.03619614616036415,
0.056745849549770355,
0.026561910286545753,
-0.09098991006612778,
-0.07576735317707062,
-0.02702508680522442,
0.016071489080786705,
0.0036362537648528814,
0.08695422112941742,
0.07329925894737244,
-0.005394064821302891,
0.03138317912817001,
0.056019291281700134,
0.06918874382972717,
0.05461718887090683,
-0.021965717896819115,
-0.04685364291071892,
0.04196666181087494,
-0.054852381348609924,
-0.07991982251405716,
-0.0430583693087101,
-0.04617347568273544,
-0.00044598287786357105,
-0.023753201588988304,
-0.01624116860330105,
0.06893114000558853,
-0.004815882537513971,
0.03026946261525154,
-0.008826768957078457,
0.02674933150410652,
0.005418998189270496,
0.057446639984846115,
-0.09121216833591461,
0.10779071599245071,
-0.033100858330726624,
-0.001960204681381583,
-0.024605071172118187,
0.06347989290952682,
0.02767535299062729,
-0.006782755721360445,
-0.07450876384973526,
-0.029449082911014557,
0.038496918976306915,
0.020161934196949005,
0.028175123035907745,
-0.05499028414487839,
0.039460837841033936,
0.030269579961895943,
-0.09644024819135666,
0.07863661646842957,
0.09676864743232727,
0.007818701677024364,
0.10841996222734451,
0.02433801256120205,
0.05008159950375557,
-0.06611797213554382,
-0.002377129392698407,
-0.0022053809370845556,
0.007258294615894556,
-0.04679177328944206,
-3.098081791108598e-8,
0.03470294177532196,
-0.05637295916676521,
0.013461071997880936,
-0.0833357721567154,
-0.010570256970822811,
-0.07210525870323181,
0.021290600299835205,
-0.0048179361037909985,
-0.021336225792765617,
-0.004144561477005482,
-0.010431148111820221,
0.039888378232717514,
-0.07205221056938171,
-0.08356699347496033,
0.0641825869679451,
-0.04775737226009369,
-0.03271527215838432,
0.024461785331368446,
-0.0170479454100132,
-0.048020511865615845,
0.0009326272993348539,
-0.0822487324476242,
0.011656729504466057,
0.02787681110203266,
0.047928713262081146,
0.029082143679261208,
0.010996006429195404,
0.12274262309074402,
0.01692425273358822,
0.010092777200043201,
0.08085385710000992,
-0.12215723842382431,
0.03387897089123726,
-0.04472525045275688,
0.029939020052552223,
-0.002142511075362563,
0.05029556155204773,
-0.014486496336758137,
0.10644245147705078,
0.036954980343580246,
-0.046238332986831665,
0.026121681556105614,
-0.007810073904693127,
0.034616511315107346,
-0.05472670495510101,
-0.006753940135240555,
0.05378604307770729,
0.08825106173753738,
0.0017715925350785255,
-0.014052503742277622,
-0.07694565504789352,
-0.07760946452617645,
-0.0872316062450409,
-0.016577547416090965,
-0.050464287400245667,
0.0006147967069409788,
0.027438487857580185,
0.043471675366163254,
0.0460977777838707,
0.04819566011428833,
-0.040179647505283356,
0.015806978568434715,
0.10570602864027023,
0.022173134610056877
] |
PMID:33085037 | NETs are frequently characterized by high SSTRs expression levels. | [
-0.030308939516544342,
-0.07626430690288544,
-0.018285585567355156,
0.038397978991270065,
-0.00962208304554224,
0.03708060458302498,
0.002209725556895137,
0.05971610173583031,
0.04326688125729561,
-0.06573222577571869,
-0.012445823289453983,
0.0015727936988696456,
0.01271027885377407,
0.016640815883874893,
0.011487191542983055,
-0.001990433083847165,
-0.02575056441128254,
0.010158145800232887,
0.006421074736863375,
-0.06874074041843414,
0.04104284569621086,
0.05270408093929291,
-0.08848078548908234,
-0.020235082134604454,
0.03612441569566727,
-0.04814984276890755,
-0.020519951358437538,
-0.028765646740794182,
0.03344756364822388,
0.007906690239906311,
-0.07444265484809875,
0.06819528341293335,
-0.00528612919151783,
0.031037094071507454,
-0.013789935037493706,
-0.007204181514680386,
-0.045051563531160355,
0.02369718626141548,
-0.051287293434143066,
0.0013003669446334243,
0.03380924090743065,
-0.04688693955540657,
-0.0038087181746959686,
-0.020504586398601532,
-0.023579934611916542,
-0.0064950427040457726,
-0.054764844477176666,
-0.054936524480581284,
-0.058430127799510956,
-0.04941674694418907,
-0.060037512332201004,
0.01886666752398014,
0.010020313784480095,
0.09991001337766647,
0.11895214021205902,
0.02766231633722782,
-0.03629583865404129,
-0.05141215771436691,
-0.011275731958448887,
0.04726698249578476,
-0.039989955723285675,
-0.05949496477842331,
-0.023622697219252586,
-0.03720485419034958,
0.12204157561063766,
0.07979020476341248,
0.014921605587005615,
0.03188721090555191,
0.04658716544508934,
0.055324915796518326,
-0.060917213559150696,
0.038632914423942566,
-0.1260579228401184,
0.14170505106449127,
0.1051521897315979,
0.03950284793972969,
-0.0271757822483778,
-0.04979541525244713,
0.0862772986292839,
-0.051165591925382614,
-0.007462349254637957,
0.03671541064977646,
-0.02211347594857216,
0.07964057475328445,
0.051728636026382446,
0.022903012111783028,
-0.0671079158782959,
-0.07724921405315399,
-0.04314310476183891,
0.10442239791154861,
0.015039452351629734,
-0.06308060139417648,
0.00019456137670204043,
-0.037149637937545776,
0.036081504076719284,
0.020797887817025185,
-0.05591148883104324,
-0.08199085295200348,
0.012259140610694885,
-0.038712888956069946,
0.011514140293002129,
0.039619430899620056,
-0.056058406829833984,
-0.016589775681495667,
-0.04158377647399902,
0.05375371500849724,
0.06978471577167511,
0.03169926628470421,
0.00022975174942985177,
-0.06796018779277802,
-0.02863183245062828,
-0.04076218977570534,
0.03935350477695465,
-0.08665340393781662,
-0.0464414618909359,
-0.03361126780509949,
0.0020017814822494984,
0.024617210030555725,
0.06274273991584778,
0.022755231708288193,
-0.07999169826507568,
0.012989522889256477,
-0.05161111056804657,
0.016642939299345016,
-0.004456446971744299,
0.0015865553868934512,
-0.15057039260864258,
-7.726920178943337e-34,
0.08144637197256088,
0.06855618208646774,
-0.03468814864754677,
0.04255079850554466,
-0.01657983846962452,
-0.02699006348848343,
-0.06813236325979233,
-0.0661201924085617,
0.01971389912068844,
0.11808329820632935,
-0.12019236385822296,
0.022719308733940125,
-0.07960513979196548,
0.014799301512539387,
0.06924699246883392,
-0.07692300528287888,
-0.012887919321656227,
0.07772833108901978,
-0.02979120798408985,
-0.06807149201631546,
-0.0008344436646439135,
-0.03231043741106987,
0.003888428211212158,
-0.06466080993413925,
0.0775400772690773,
-0.034059200435876846,
-0.03168265521526337,
0.001044273842126131,
0.005054341163486242,
0.027299465611577034,
-0.03943776339292526,
0.03388587012887001,
-0.001244192710146308,
0.017012394964694977,
0.07522525638341904,
-0.0084530059248209,
0.0635925829410553,
-0.008088042959570885,
0.0642533078789711,
0.003453963901847601,
0.04044421389698982,
0.030654311180114746,
-0.06931166350841522,
0.048781830817461014,
0.008149873465299606,
-0.003352321218699217,
-0.07583101093769073,
0.040905918926000595,
-0.030130112543702126,
0.07351302355527878,
-0.017915034666657448,
0.03863542154431343,
0.036992426961660385,
-0.012503991834819317,
-0.004290314391255379,
0.007525373250246048,
0.017190057784318924,
0.037740085273981094,
0.009231088683009148,
0.11811996251344681,
-0.05871027335524559,
0.018046827986836433,
-0.08598363399505615,
0.021143855527043343,
0.002185392426326871,
0.07402276247739792,
-0.03438875079154968,
0.0021297531202435493,
0.017840800806879997,
0.012331037782132626,
-0.009050814434885979,
0.04962053894996643,
0.06008784472942352,
-0.028349619358778,
0.017940765246748924,
-0.054587144404649734,
-0.026127854362130165,
0.08314282447099686,
-0.016801219433546066,
0.019820570945739746,
-0.028606364503502846,
0.04519343003630638,
-0.0903029814362526,
0.0028026048094034195,
0.003915878478437662,
-0.05184222385287285,
-0.010892095975577831,
-0.14694249629974365,
-0.08882332593202591,
0.013391431421041489,
0.06671633571386337,
-0.052692826837301254,
0.06278254091739655,
0.05938325077295303,
-0.07866454869508743,
-3.457044856289363e-34,
-0.10599949210882187,
-0.009377698414027691,
0.002297665225341916,
-0.042444031685590744,
-0.07697375863790512,
-0.024821916595101357,
0.04606969282031059,
-0.025893934071063995,
0.04540735110640526,
0.03585098683834076,
0.07758935540914536,
0.04915856942534447,
-0.007321980316191912,
-0.06820272654294968,
0.06069883331656456,
-0.030421754345297813,
-0.01168171875178814,
0.01420179195702076,
0.04935465380549431,
-0.022412307560443878,
0.024446986615657806,
0.058581799268722534,
-0.049192916601896286,
0.06552982330322266,
0.02654089219868183,
0.039029210805892944,
-0.10274504125118256,
0.08158432692289352,
0.00207600649446249,
0.05769363045692444,
-0.018091488629579544,
0.028679946437478065,
-0.02153903618454933,
0.020604977384209633,
-0.057038795202970505,
-0.022897038608789444,
0.03888767957687378,
-0.01248108223080635,
0.01603279449045658,
-0.058928657323122025,
0.051199037581682205,
0.007010291796177626,
-0.023927738890051842,
0.034243617206811905,
0.047325193881988525,
0.007255816366523504,
-0.004674541298300028,
-0.048238907009363174,
0.03624793142080307,
-0.003986767493188381,
0.011742723174393177,
0.0034130215644836426,
-0.004268629010766745,
0.03982119634747505,
-0.06668882817029953,
-0.015181821770966053,
-0.04364900290966034,
0.0028109608683735132,
-0.00764246704056859,
-0.03720729053020477,
0.023174677044153214,
-0.030596239492297173,
-0.0485120564699173,
0.04634629189968109,
0.0508282445371151,
-0.007100669667124748,
0.07935157418251038,
-0.05420687794685364,
0.04293803870677948,
-0.0908779576420784,
0.058700475841760635,
-0.0053382390178740025,
-0.0047728922218084335,
-0.045010652393102646,
-0.06961050629615784,
-0.09808065742254257,
-0.0508769266307354,
0.030265677720308304,
-0.03393293172121048,
0.08904500305652618,
-0.07549238950014114,
0.08045551925897598,
-0.006811667233705521,
-0.04604174941778183,
0.08283375203609467,
0.04987029358744621,
-0.03449348360300064,
0.12820865213871002,
0.05386737734079361,
0.024845601990818977,
-0.08276353776454926,
0.00230220053344965,
-0.0878569632768631,
0.06883113086223602,
-0.04739831015467644,
-1.8652981381706013e-8,
-0.030899975448846817,
0.02963007055222988,
-0.027873743325471878,
-0.027488525956869125,
0.09761166572570801,
0.01046865712851286,
-0.03980022296309471,
0.08203502744436264,
0.01876184344291687,
-0.020002353936433792,
-0.014599582180380821,
0.0003708361473400146,
-0.07799560576677322,
-0.11773213744163513,
0.15581689774990082,
-0.04910179227590561,
-0.03401999920606613,
0.00006957891309866682,
-0.003195221535861492,
-0.05197504907846451,
0.03676609322428703,
0.002476559719070792,
0.07407758384943008,
0.08275646716356277,
-0.07329808920621872,
-0.02242191694676876,
0.026788990944623947,
0.03976975008845329,
-0.026827702298760414,
0.04921003803610802,
0.018003996461629868,
-0.030277028679847717,
0.008288291282951832,
0.036773379892110825,
0.0058869426138699055,
0.09652094542980194,
-0.04052666947245598,
-0.01908452995121479,
0.022890660911798477,
0.1276543140411377,
-0.037446312606334686,
-0.04431122541427612,
-0.01384921744465828,
0.07613034546375275,
-0.007414488587528467,
0.03033328801393509,
-0.02440205216407776,
0.06444486230611801,
0.03578536957502365,
-0.05769050121307373,
0.010417242534458637,
-0.006617997772991657,
-0.04328273981809616,
0.0379326194524765,
-0.014775545336306095,
0.012154902331531048,
0.03201916813850403,
0.014083385467529297,
-0.003321041353046894,
0.06717555224895477,
0.05185536667704582,
0.042218588292598724,
0.006010154262185097,
0.005914222449064255
] |
PMID:33085037 | SST analogues (SSAs) that bind and activate SSTR have anti-proliferative and anti-secretory activity, thereby reducing both the growth as well as the hormonal symptoms of NETs. | [
-0.08491913229227066,
-0.05282653495669365,
-0.08340558409690857,
0.06442032009363174,
0.009936006739735603,
0.10474158078432083,
0.026873083785176277,
0.09578045457601547,
0.07586589455604553,
-0.0032628660555928946,
0.0673879086971283,
0.04382649436593056,
-0.01049356535077095,
0.014472825452685356,
0.055134959518909454,
0.03044578619301319,
-0.05097861960530281,
0.030052345246076584,
0.08546151220798492,
-0.05291246622800827,
0.027883293107151985,
0.03947482630610466,
-0.042109258472919464,
0.020610179752111435,
-0.00887842383235693,
0.003875911235809326,
-0.04288443177938461,
-0.030353954061865807,
-0.00802125409245491,
0.0068831052631139755,
-0.0427030473947525,
0.04630624130368233,
-0.034002579748630524,
-0.007316960021853447,
-0.06452406197786331,
-0.05670240893959999,
-0.07532355934381485,
-0.004163328558206558,
-0.052529506385326385,
0.001789684989489615,
0.07005317509174347,
-0.03933858498930931,
-0.08335133641958237,
-0.042120568454265594,
-0.022418208420276642,
-0.07701235264539719,
-0.07053947448730469,
-0.038652170449495316,
-0.05459614843130112,
0.02456754446029663,
-0.01772782951593399,
-0.08276522159576416,
0.011873164214193821,
0.12138962000608444,
0.07276850193738937,
-0.003071689046919346,
-0.028527796268463135,
-0.010779461823403835,
-0.00799719337373972,
0.03222198411822319,
-0.025199459865689278,
-0.043313801288604736,
-0.018632911145687103,
-0.036514025181531906,
0.133729487657547,
0.06562022119760513,
-0.013054129667580128,
0.046269744634628296,
-0.0017205631593242288,
0.025265799835324287,
0.002928221831098199,
-0.0010616159997880459,
-0.07295789569616318,
0.11946281790733337,
0.07923166453838348,
-0.011522996239364147,
-0.06172532960772514,
-0.019713077694177628,
0.027979250997304916,
0.029626963660120964,
-0.004397345706820488,
0.08940242230892181,
0.023034345358610153,
0.1404321938753128,
0.013914631679654121,
0.07511455565690994,
-0.005194945260882378,
-0.039623212069272995,
-0.015499808825552464,
0.09558439254760742,
0.01866295002400875,
-0.03712478652596474,
-0.06859500706195831,
-0.021352242678403854,
0.002450052183121443,
-0.042672839015722275,
-0.1320028007030487,
-0.027765240520238876,
-0.06864453852176666,
-0.0596119724214077,
-0.01906914822757244,
0.03529232367873192,
-0.11943787336349487,
-0.01933034136891365,
-0.02639302983880043,
0.05626070499420166,
0.037984348833560944,
-0.09655632823705673,
-0.004672192502766848,
0.014576348476111889,
-0.017920399084687233,
-0.047936566174030304,
0.03448875993490219,
-0.021419545635581017,
-0.06759406626224518,
0.03301858529448509,
0.02323172427713871,
0.057439833879470825,
0.01726387068629265,
-0.09044252336025238,
-0.010948781855404377,
-0.006320712622255087,
-0.02006351202726364,
-0.014111305586993694,
0.00333768199197948,
0.043279979377985,
-0.11565421521663666,
-6.983335054214294e-34,
0.05959239974617958,
0.0078768040984869,
0.00483335554599762,
0.06748021394014359,
0.03158605843782425,
0.05022226646542549,
-0.017411887645721436,
-0.07019200921058655,
0.06384800374507904,
0.04848674312233925,
-0.09787780046463013,
-0.007505570072680712,
-0.06265658140182495,
0.018584415316581726,
0.027090825140476227,
-0.08773136138916016,
-0.016983630135655403,
0.02544441819190979,
0.05542000010609627,
-0.0687846839427948,
0.029273949563503265,
0.02833067812025547,
0.051936548203229904,
-0.05215192586183548,
0.05625054985284805,
-0.04540291428565979,
-0.010732033289968967,
0.08848993480205536,
-0.0076827979646623135,
0.01140147726982832,
-0.05154912918806076,
0.011917617172002792,
-0.008425858803093433,
-0.008657301776111126,
0.05506741255521774,
-0.055587705224752426,
0.04598311334848404,
-0.05866605415940285,
0.032943859696388245,
0.015624738298356533,
0.12701520323753357,
-0.010018652305006981,
-0.04906006157398224,
0.03013915754854679,
0.026374593377113342,
-0.019710009917616844,
-0.05100829526782036,
-0.0035531925968825817,
0.051923736929893494,
0.06137097254395485,
0.009029892273247242,
0.024129921570420265,
-0.020541822537779808,
-0.0433492511510849,
-0.04772529378533363,
0.04869411513209343,
-0.0573531873524189,
-0.043993789702653885,
-0.0051084160804748535,
0.04518431797623634,
-0.07073966413736343,
-0.10901589691638947,
-0.030070127919316292,
0.05975450947880745,
-0.0243353433907032,
0.06887577474117279,
-0.06638679653406143,
-0.07953612506389618,
-0.058047957718372345,
0.011205133982002735,
0.0035271858796477318,
-0.03172014281153679,
0.07219792157411575,
-0.0168705265969038,
0.034626539796590805,
-0.052459586411714554,
-0.03980721905827522,
0.14201658964157104,
-0.016058657318353653,
0.011493189260363579,
0.004347979091107845,
-0.023095525801181793,
-0.05576448142528534,
0.07634315639734268,
0.018655728548765182,
-0.06628720462322235,
0.007426679600030184,
-0.05809614434838295,
-0.020934967324137688,
-0.033360596746206284,
0.09303877502679825,
-0.03751883655786514,
0.030777601525187492,
0.1074058935046196,
-0.05847674608230591,
-9.08678530856233e-34,
-0.05487743765115738,
-0.03300385922193527,
0.027796456590294838,
-0.05094516649842262,
-0.007394883316010237,
0.028036708012223244,
0.03365734964609146,
0.0023742937482893467,
0.03550726920366287,
0.02843184769153595,
0.10279726982116699,
0.02625439316034317,
-0.05318530276417732,
-0.05368231236934662,
0.03884636610746384,
-0.009044407866895199,
0.04830870404839516,
-0.0027619327884167433,
-0.028888963162899017,
-0.06844376027584076,
-0.005331509746611118,
0.04863451421260834,
-0.009953801520168781,
0.055005621165037155,
0.0721520483493805,
0.01428917609155178,
-0.026338718831539154,
0.13187681138515472,
-0.013519837521016598,
0.08071215450763702,
-0.0008600772707723081,
0.03800554946064949,
-0.023930374532938004,
-0.004760578740388155,
-0.02204485610127449,
0.013339695520699024,
0.08137402683496475,
0.0314960852265358,
0.0062224967405200005,
-0.0832991972565651,
-0.01071631908416748,
-0.018414445221424103,
-0.005594674963504076,
0.044358063489198685,
0.0929790809750557,
0.05308699607849121,
0.021587800234556198,
0.03599167242646217,
0.003848311258479953,
0.027975155040621758,
0.048502855002880096,
-0.027721906080842018,
0.010560662485659122,
-0.011635887436568737,
-0.01734120212495327,
-0.0441790446639061,
-0.03002951666712761,
-0.009749756194651127,
-0.013188844546675682,
0.006414142437279224,
0.04983680695295334,
-0.040611498057842255,
0.0009221089421771467,
-0.018427062779664993,
-0.0375400185585022,
-0.022638468071818352,
0.04916810989379883,
-0.03727835416793823,
0.11660800874233246,
-0.03328419476747513,
0.04138439893722534,
0.03363223746418953,
-0.030321896076202393,
-0.06352392584085464,
-0.03732287511229515,
-0.07749339193105698,
-0.08969928324222565,
-0.008156683295965195,
-0.0009576085139997303,
0.025611786171793938,
-0.1134621873497963,
0.022007104009389877,
-0.021718308329582214,
-0.1117078959941864,
0.05262337625026703,
0.08202316612005234,
-0.00794514175504446,
0.06564532965421677,
-0.017435023561120033,
0.12448927015066147,
-0.12008529901504517,
-0.0036107394844293594,
-0.05125024914741516,
0.05364452302455902,
0.0062941028736531734,
-3.2043505626688784e-8,
0.0338708721101284,
-0.011501015163958073,
0.019835911691188812,
-0.06483287364244461,
0.01773812808096409,
-0.12914951145648956,
-0.03510315716266632,
0.03310934454202652,
0.07763195037841797,
-0.021186886355280876,
-0.05477580428123474,
0.07373334467411041,
-0.007129928097128868,
-0.03944965451955795,
0.07900087535381317,
-0.028164172545075417,
-0.03129711374640465,
0.03763837367296219,
-0.04115971177816391,
-0.08497181534767151,
0.0365208238363266,
-0.02776690572500229,
0.015351591631770134,
0.0644012913107872,
-0.021386172622442245,
-0.03615538775920868,
0.05621889606118202,
0.052034638822078705,
0.013867411762475967,
-0.01772027462720871,
0.058738332241773605,
-0.031054910272359848,
0.03721920773386955,
0.04629825800657272,
-0.041861336678266525,
0.030611423775553703,
0.014119785279035568,
-0.03207850828766823,
0.0671900287270546,
0.08863060921430588,
-0.04253013804554939,
-0.033672478049993515,
0.000024293642127304338,
0.03318607062101364,
-0.07493600249290466,
0.000029576809538411908,
0.021160980686545372,
0.03279683366417885,
0.006537753622978926,
-0.058533910661935806,
-0.010291661135852337,
-0.026426121592521667,
-0.051622096449136734,
0.016401134431362152,
-0.06298986822366714,
0.021950464695692062,
0.04802605137228966,
0.047634877264499664,
0.04841795191168785,
0.03465750440955162,
-0.013365407474339008,
-0.01912267506122589,
0.05609184131026268,
0.024509456008672714
] |
PMID:33085037 | Moreover, the high expression levels of SSTR type-2 (SSTR2) in NETs is a powerful target for therapy with radiolabeled SSAs. | [
-0.010453145951032639,
-0.049238093197345734,
-0.06025686487555504,
0.05856674164533615,
-0.0432637557387352,
0.053324513137340546,
-0.0032561991829425097,
0.10552443563938141,
-0.0021495993714779615,
-0.06869536638259888,
-0.009541320614516735,
0.011981697753071785,
0.04438957944512367,
0.055793844163417816,
0.04533615708351135,
0.02511698007583618,
0.004238012246787548,
-0.004206416662782431,
0.08252997696399689,
-0.041678499430418015,
-0.021037403494119644,
0.061717357486486435,
-0.017469186335802078,
-0.01813827082514763,
0.021169472485780716,
-0.022587908431887627,
-0.049517661333084106,
-0.021562565118074417,
-0.002740319585427642,
-0.004711554851382971,
-0.004391022026538849,
0.043842095881700516,
-0.0713973417878151,
0.01709689013659954,
-0.017460640519857407,
-0.07841741293668747,
-0.08300451189279556,
0.06177176535129547,
-0.10635747760534286,
-0.05059175565838814,
0.05795510485768318,
-0.0421537384390831,
-0.05713360384106636,
-0.052131980657577515,
-0.024331554770469666,
-0.10488290339708328,
-0.033529460430145264,
-0.10213436186313629,
-0.0030427598394453526,
0.03732762485742569,
-0.0456162765622139,
-0.03281030058860779,
0.018721168860793114,
0.14889462292194366,
0.08773759752511978,
0.0010171199683099985,
-0.04311426728963852,
0.021763300523161888,
0.02017238177359104,
0.09352438896894455,
-0.018575072288513184,
-0.08125709742307663,
0.02048037014901638,
-0.05179980397224426,
0.15580573678016663,
0.04385869950056076,
0.000032584597647655755,
-0.02550251968204975,
-0.0013537723571062088,
0.052476298063993454,
-0.01921914704144001,
-0.018565621227025986,
-0.013950176537036896,
0.09638016670942307,
0.051459331065416336,
-0.039683640003204346,
-0.01160274725407362,
-0.0012671066215261817,
0.09385386854410172,
0.037929560989141464,
-0.03130559250712395,
0.023679448291659355,
-0.018795354291796684,
0.09252587705850601,
0.02541622333228588,
0.07063421607017517,
-0.023559091612696648,
-0.02881433069705963,
-0.03968333452939987,
0.1326773315668106,
0.03056894987821579,
0.04651572182774544,
-0.014905756339430809,
-0.06376907974481583,
0.035273462533950806,
-0.012777277268469334,
-0.09175609797239304,
-0.031127827242016792,
0.0032428232952952385,
-0.06069311127066612,
0.01806662231683731,
0.019538870081305504,
-0.10411793738603592,
-0.06824914366006851,
-0.040549833327531815,
-0.008044769987463951,
0.04617540165781975,
-0.04297857731580734,
-0.037315767258405685,
-0.03713160380721092,
0.021784568205475807,
-0.024471338838338852,
-0.0019658119417726994,
0.02443852461874485,
-0.050243593752384186,
0.08555400371551514,
0.01511308178305626,
0.0405721515417099,
0.01702897623181343,
-0.018748514354228973,
-0.024769045412540436,
-0.03286359831690788,
-0.0327729694545269,
-0.04045809432864189,
0.008198204450309277,
0.023867178708314896,
-0.09169989079236984,
-1.2983059598343692e-33,
0.03365306556224823,
0.08005759119987488,
-0.022131871432065964,
0.07517649233341217,
0.02008192241191864,
-0.02922135405242443,
-0.07650429010391235,
-0.059849828481674194,
0.04597961902618408,
0.06146527826786041,
-0.0962679386138916,
-0.0033159300219267607,
-0.031511928886175156,
0.051627326756715775,
0.017741549760103226,
-0.08639197051525116,
-0.034872062504291534,
0.06283676624298096,
-0.023715946823358536,
-0.09122268855571747,
0.05755356326699257,
0.021342366933822632,
0.03672785311937332,
-0.014531059190630913,
0.06790897250175476,
-0.006867767311632633,
-0.02800123021006584,
0.0439000278711319,
0.0773068442940712,
0.01608525589108467,
-0.0908941924571991,
-0.007300544064491987,
0.040038734674453735,
-0.015932567417621613,
0.058449938893318176,
-0.03708486258983612,
0.05185519531369209,
-0.016604283824563026,
0.05389440059661865,
0.010071156546473503,
0.13702714443206787,
0.06051843985915184,
-0.03395272046327591,
0.04023927450180054,
0.05030404403805733,
-0.08280955255031586,
-0.006671105045825243,
-0.0335436686873436,
-0.01352617982774973,
0.0444817952811718,
-0.04068205878138542,
-0.012879133224487305,
-0.009416257031261921,
-0.0031596834305673838,
0.013530720956623554,
0.0281161367893219,
-0.03619907796382904,
0.0494246706366539,
0.03436048701405525,
0.061295874416828156,
-0.0811205729842186,
-0.036598823964595795,
-0.010313923470675945,
0.0018731002928689122,
0.012464586645364761,
0.005112379789352417,
-0.05152444541454315,
-0.04814776033163071,
-0.11549028009176254,
0.022106215357780457,
0.024110905826091766,
-0.009128396399319172,
0.059729304164648056,
-0.006965611595660448,
0.04434770718216896,
-0.059963300824165344,
-0.005088621284812689,
0.12420614063739777,
-0.006684516090899706,
0.0454864501953125,
-0.005131883081048727,
0.0056471251882612705,
-0.11200171709060669,
0.06094268709421158,
0.04390307515859604,
-0.0754355862736702,
-0.040988292545080185,
-0.12025438249111176,
-0.06302718818187714,
0.023865919560194016,
0.0982242152094841,
0.01582597754895687,
0.0014725991059094667,
0.029106156900525093,
-0.02948971837759018,
-4.294186015196917e-34,
-0.09179612994194031,
-0.018245702609419823,
0.08615351468324661,
-0.07966852188110352,
-0.010320995002985,
0.0038028585258871317,
0.02053253911435604,
-0.020468449220061302,
0.09629510343074799,
0.03735635057091713,
0.11315586417913437,
0.039756521582603455,
-0.01918209344148636,
-0.040281761437654495,
-0.022310946136713028,
-0.01926385797560215,
-0.0028377582784742117,
0.01088150404393673,
-0.014124979265034199,
-0.05365749076008797,
0.05481143668293953,
0.07475754618644714,
0.06645137816667557,
0.05346563830971718,
0.047911204397678375,
0.011798867955803871,
0.033167630434036255,
0.09219150245189667,
0.08819587528705597,
0.04932763800024986,
-0.04673338308930397,
0.0010799778392538428,
-0.033726442605257034,
-0.008954345248639584,
0.038127440959215164,
-0.03241714835166931,
0.06687090545892715,
0.0073074339888989925,
-0.017106974497437477,
-0.07062303274869919,
-0.00147768494207412,
0.0015730280429124832,
-0.04415196180343628,
0.05019962787628174,
0.03925403580069542,
-0.04640881344676018,
0.049002692103385925,
0.02368088811635971,
0.003015831345692277,
-0.008604660630226135,
0.02146167866885662,
-0.03857643902301788,
-0.0012056304840371013,
0.002533730585128069,
-0.0368344709277153,
-0.11746145784854889,
-0.02213197574019432,
-0.03576850891113281,
-0.06260747462511063,
-0.04192514345049858,
0.0207907035946846,
-0.0036671084817498922,
0.02806731127202511,
-0.016333481296896935,
0.0034709321334958076,
0.008424208499491215,
0.062086720019578934,
0.007956841960549355,
-0.0003976502630393952,
-0.03411324322223663,
0.030440613627433777,
-0.02069375105202198,
-0.03481137752532959,
-0.030504198744893074,
-0.048319604247808456,
-0.04232177138328552,
-0.06807076185941696,
0.02631077729165554,
0.005570811219513416,
-0.007222162093967199,
-0.02221834473311901,
0.08179464191198349,
-0.03732779622077942,
-0.11007478833198547,
0.12927623093128204,
0.0781823992729187,
-0.006927195005118847,
0.0920921266078949,
-0.0088629936799407,
0.027859196066856384,
-0.08707408607006073,
-0.01751122437417507,
-0.03291688486933708,
0.07441765815019608,
-0.057905882596969604,
-2.699063372801902e-8,
-0.03165043517947197,
-0.0330391563475132,
0.0181263480335474,
-0.06519732624292374,
0.0097888745367527,
-0.03164106234908104,
-0.10178036987781525,
0.04597644507884979,
0.0027030915953218937,
-0.01154016237705946,
-0.04603404924273491,
0.07487942278385162,
0.007200020831078291,
-0.0799928829073906,
0.09970592707395554,
-0.005176515318453312,
-0.00970959197729826,
-0.0009370472398586571,
0.016536323353648186,
-0.059667594730854034,
0.014195638708770275,
-0.08311520516872406,
0.05903593450784683,
0.05027613043785095,
-0.06147761270403862,
0.02720879390835762,
0.05867942422628403,
0.015282669104635715,
0.014343799091875553,
-0.04531009495258331,
0.04221084713935852,
-0.04904920235276222,
0.019159924238920212,
0.04885425046086311,
-0.04085296764969826,
-0.0013765365583822131,
0.010179789736866951,
-0.02706807292997837,
0.0019861769396811724,
0.12763673067092896,
-0.021271977573633194,
0.024277986958622932,
-0.005552946124225855,
0.031555917114019394,
-0.10767032951116562,
-0.00037835785769857466,
0.003996037878096104,
0.028152480721473694,
-0.007595853414386511,
-0.09601284563541412,
0.003492383286356926,
-0.06723849475383759,
-0.05482780933380127,
-0.05387524515390396,
-0.1026684120297432,
0.047834042459726334,
0.048740409314632416,
0.01622951216995716,
0.02549993246793747,
0.02825118973851204,
0.0002663924533408135,
0.018905941396951675,
0.015142637304961681,
0.03465460613369942
] |
PMID:33085037 | Due to the important role of both SST and SSTRs, it is of great importance to elucidate the mechanisms involved in regulating their expression in NETs, as well as in other types of tumors. | [
-0.04025577753782272,
-0.048170700669288635,
-0.062456097453832626,
-0.033417969942092896,
0.017820637673139572,
0.07900997996330261,
0.02022608183324337,
0.059469398111104965,
0.07720720022916794,
-0.03526877239346504,
-0.015512079000473022,
0.04879350587725639,
-0.007204216439276934,
0.005880075506865978,
0.000695584574714303,
0.033802833408117294,
-0.12152833491563797,
0.04645674303174019,
0.025369474664330482,
-0.07997559756040573,
-0.0014992953510954976,
-0.01962137222290039,
-0.03657454252243042,
-0.01716756634414196,
0.023138515651226044,
-0.04151435196399689,
0.003697301261126995,
0.00271232589147985,
-0.04444936662912369,
0.003314716275781393,
-0.041506655514240265,
-0.03143424168229103,
-0.0825142189860344,
-0.0024167047813534737,
-0.08369903266429901,
-0.01327288243919611,
-0.05833764746785164,
-0.010838039219379425,
-0.06645247340202332,
-0.01403728500008583,
0.037138681858778,
-0.040894750505685806,
-0.026392871513962746,
-0.025131667032837868,
0.017516884952783585,
-0.07890572398900986,
-0.07957024872303009,
-0.08876194059848785,
-0.045938778668642044,
0.05200481042265892,
-0.053068891167640686,
0.008505595847964287,
-0.022149937227368355,
0.08872633427381516,
0.09346656501293182,
0.05448026955127716,
-0.02033829875290394,
0.01731191761791706,
0.0018075318075716496,
-0.008977026678621769,
0.004576320294290781,
-0.11214269697666168,
0.019507993012666702,
-0.054399553686380386,
0.09413939714431763,
-0.022661417722702026,
0.012462860904633999,
0.014344281516969204,
-0.05372520908713341,
0.06417042762041092,
0.025774391368031502,
-0.01741502620279789,
-0.059960201382637024,
0.08132494986057281,
0.0067835417576134205,
0.017580276355147362,
-0.013777841813862324,
0.02355305850505829,
0.03692217543721199,
0.032517556101083755,
0.03378622978925705,
0.10830915719270706,
0.07218994200229645,
0.0862027183175087,
-0.0062591442838311195,
0.04175221920013428,
-0.03856967017054558,
-0.00898209773004055,
-0.04860587418079376,
0.1401415914297104,
0.05731842666864395,
-0.020529739558696747,
-0.045285485684871674,
-0.06315045058727264,
0.005583380814641714,
-0.03852688893675804,
-0.04590119794011116,
-0.04438880458474159,
0.038444772362709045,
-0.10455713421106339,
-0.018712960183620453,
-0.003944783005863428,
-0.06095224618911743,
-0.02713223546743393,
-0.037389107048511505,
0.031018169596791267,
0.019766421988606453,
-0.015435959212481976,
-0.02581731602549553,
-0.040828071534633636,
0.007768572308123112,
-0.03459272161126137,
0.045838549733161926,
-0.012646631337702274,
-0.02826308272778988,
0.06757310777902603,
-0.06147528812289238,
0.01429835706949234,
0.04113871976733208,
-0.045738335698843,
-0.0552494116127491,
0.006268259137868881,
-0.022499511018395424,
0.0008883925038389862,
0.011717972345650196,
0.054242853075265884,
-0.1302393078804016,
-2.3718357266144237e-33,
0.1117001548409462,
0.017711816355586052,
-0.01064301934093237,
0.05966639891266823,
0.014152969233691692,
0.005941589362919331,
-0.06486286222934723,
-0.08723689615726471,
-0.014624261297285557,
0.002932971576228738,
-0.07926484942436218,
-0.05188191309571266,
-0.01868869923055172,
0.0033233414869755507,
-0.03963014855980873,
-0.06368554383516312,
-0.012204199098050594,
0.02024698071181774,
0.011951552703976631,
-0.10193994641304016,
-0.007765991147607565,
0.013897238299250603,
-0.011931268498301506,
-0.080357126891613,
0.01218123733997345,
-0.02839014306664467,
-0.04903852194547653,
0.062343012541532516,
0.01350337266921997,
0.009525628760457039,
-0.07687153667211533,
0.026947230100631714,
-0.007763480301946402,
0.022244786843657494,
0.0811556875705719,
0.002519771223887801,
0.02059153839945793,
-0.06892737001180649,
0.06813071668148041,
0.07126107066869736,
0.14285199344158173,
-0.01635073497891426,
-0.03004286251962185,
0.0040407744236290455,
0.049703408032655716,
-0.014583077281713486,
-0.05285832658410072,
0.050167858600616455,
0.014176546595990658,
0.0671687126159668,
-0.004233573563396931,
0.011414382606744766,
0.007745987735688686,
-0.020990625023841858,
-0.0012237151386216283,
0.029627962037920952,
-0.1340678483247757,
-0.029856190085411072,
-0.03197966888546944,
0.051530301570892334,
-0.06334107369184494,
-0.11049490422010422,
-0.010097590275108814,
0.06908699125051498,
0.0526808463037014,
0.0745110809803009,
-0.08532886207103729,
-0.05923692137002945,
-0.06260888278484344,
-0.0007563414983451366,
-0.0389200896024704,
-0.007148202043026686,
0.1059354767203331,
-0.04753599688410759,
0.03580770641565323,
0.010632090270519257,
-0.01746603474020958,
0.1335466504096985,
-0.022101841866970062,
0.10013191401958466,
-0.017641229555010796,
0.0029602530412375927,
-0.08077710121870041,
0.00335114449262619,
0.04268574342131615,
-0.07440593093633652,
0.037068240344524384,
-0.09392938762903214,
-0.02768978290259838,
0.022051401436328888,
0.04019610583782196,
-0.04912311211228371,
-0.02946745976805687,
0.07659664750099182,
-0.021799517795443535,
-2.1565015082620967e-33,
-0.04602859169244766,
-0.0491100549697876,
0.058315422385931015,
-0.059768714010715485,
-0.05004042759537697,
0.09147267788648605,
0.013359731994569302,
-0.07835733890533447,
-0.005136490799486637,
0.022366538643836975,
0.0570354163646698,
0.06443201005458832,
-0.03808830305933952,
-0.12502411007881165,
-0.017733009532094002,
-0.05761169642210007,
-0.013949930667877197,
0.04867701977491379,
-0.01962357573211193,
-0.06515714526176453,
0.014379170723259449,
0.04869372770190239,
-0.03342975676059723,
0.07266474515199661,
0.009967636317014694,
-0.0016390446107834578,
-0.07713014632463455,
0.0578828901052475,
-0.018419401720166206,
0.07331746816635132,
-0.005019263830035925,
0.039937056601047516,
-0.06825827062129974,
-0.013359196484088898,
0.014544708654284477,
-0.004132584668695927,
0.05033159628510475,
0.018368026241660118,
0.04219065234065056,
-0.010343484580516815,
0.020558049902319908,
-0.0021699469070881605,
0.012540595605969429,
0.022171858698129654,
0.11075322329998016,
0.055961139500141144,
0.04670316353440285,
0.03284883871674538,
0.015106248669326305,
-0.00020515276992227882,
0.02022136189043522,
-0.020186560228466988,
0.012928969226777554,
-0.019937831908464432,
0.0012835226953029633,
-0.0008476775255985558,
-0.01170291192829609,
-0.0052787987515330315,
0.010617074556648731,
0.008559420704841614,
-0.006487230770289898,
-0.030365945771336555,
0.029207589104771614,
0.010600113309919834,
0.014284548349678516,
0.03678964078426361,
0.052069686353206635,
-0.04323822632431984,
0.09108689427375793,
-0.05074912682175636,
0.03589807450771332,
0.031624842435121536,
-0.00984987523406744,
0.021126562729477882,
-0.03877868875861168,
-0.018556496128439903,
-0.025475608184933662,
0.01241400558501482,
-0.0052312626503407955,
0.08381277322769165,
-0.030730443075299263,
0.06013457104563713,
-0.02075147069990635,
-0.15223373472690582,
0.09474817663431168,
0.08186567574739456,
-0.008457791060209274,
0.051850974559783936,
0.009079151786863804,
-0.006885768845677376,
-0.11153152585029602,
-0.028520649299025536,
-0.07332677394151688,
0.03804662823677063,
-0.03627588227391243,
-3.5186332070225035e-8,
0.04586901515722275,
-0.015096734277904034,
-0.0038832686841487885,
-0.08407267928123474,
-0.01006774976849556,
-0.06345982849597931,
-0.013300570659339428,
0.06194700673222542,
0.03932752460241318,
0.010883494280278683,
-0.049309153109788895,
0.018599016591906548,
-0.039937905967235565,
-0.06603749841451645,
0.12565790116786957,
-0.02351166307926178,
0.009438740089535713,
-0.0003828885091934353,
-0.021987130865454674,
-0.07276257127523422,
0.01361861638724804,
-0.10623852163553238,
0.02623472921550274,
0.12127387523651123,
-0.05110180377960205,
-0.018130609765648842,
0.04393773898482323,
0.038962651044130325,
0.01675150915980339,
0.033750902861356735,
0.042612962424755096,
-0.0646045133471489,
0.015447575598955154,
0.0327695794403553,
-0.04319591447710991,
0.05278980731964111,
0.013551348820328712,
-0.07291517406702042,
0.06905392557382584,
0.09574355185031891,
0.0009470004588365555,
-0.00834847055375576,
-0.029619494453072548,
0.04278178513050079,
-0.0639125183224678,
0.02461700700223446,
-0.006063035223633051,
0.06163136661052704,
-0.05919289588928223,
-0.02401456981897354,
-0.03816356137394905,
-0.05863555893301964,
-0.019379008561372757,
-0.017277542501688004,
-0.07127782702445984,
0.042915116995573044,
0.08283954858779907,
0.05561283603310585,
0.0735599473118782,
0.05109676718711853,
-0.08065330237150192,
0.057238902896642685,
0.08866624534130096,
-0.028681529685854912
] |
PMID:33085037 | The field of epigenetics recently gained interest in NET research, highlighting the importance of this process in regulating the expression of gene and protein expression. | [
-0.05807296186685562,
-0.02785307727754116,
-0.08092496544122696,
-0.01861509494483471,
0.02076769433915615,
0.060361310839653015,
-0.027394520118832588,
-0.0009760314133018255,
0.012423708103597164,
0.07738018035888672,
-0.015972154214978218,
-0.022770343348383904,
-0.029049424454569817,
0.027680637314915657,
0.04124680534005165,
0.09817355871200562,
-0.12239068001508713,
-0.014892679639160633,
-0.07514103502035141,
-0.06184865161776543,
0.05226360261440277,
0.05116879940032959,
0.08832648396492004,
-0.04257812723517418,
-0.052984222769737244,
-0.0658922791481018,
0.04733974114060402,
-0.017756078392267227,
0.066877581179142,
-0.03834442421793938,
0.005755739286541939,
0.06500928103923798,
0.033647321164608,
-0.033743422478437424,
-0.017207182943820953,
0.03942113742232323,
0.02036408521234989,
0.06521525979042053,
0.024275902658700943,
-0.014079205691814423,
0.07783202826976776,
-0.05365452542901039,
-0.057746779173612595,
-0.01179184764623642,
0.016003111377358437,
-0.015028261579573154,
0.06191955506801605,
-0.06364181637763977,
0.014241181313991547,
0.012907645665109158,
-0.04410403221845627,
-0.06994415074586868,
0.013544854708015919,
-0.03067723847925663,
0.039171699434518814,
0.014788133092224598,
-0.003489350201562047,
-0.06687315553426743,
-0.02332022413611412,
-0.04790623113512993,
0.072013720870018,
-0.07705480605363846,
-0.06009037047624588,
0.010312856175005436,
0.04248524829745293,
-0.0067945076152682304,
0.037325419485569,
0.00810583308339119,
-0.03332686051726341,
-0.11448200047016144,
-0.003791941562667489,
-0.034191761165857315,
-0.07224271446466446,
0.11823106557130814,
0.016851088032126427,
0.04644713178277016,
0.025636902078986168,
-0.04503427445888519,
0.04320986568927765,
0.05545712634921074,
0.03565692901611328,
0.027632053941488266,
0.12873730063438416,
0.03192570060491562,
-0.04153291881084442,
0.019631724804639816,
-0.013345842249691486,
0.07004919648170471,
0.03091660514473915,
0.03906093165278435,
-0.023814115673303604,
-0.0977553054690361,
0.10166843980550766,
0.013591660186648369,
-0.05229824036359787,
0.0443180650472641,
0.01320318691432476,
-0.07296392321586609,
0.03827134892344475,
-0.01455527450889349,
-0.0025931764394044876,
-0.01909336820244789,
-0.09042958170175552,
0.04117295518517494,
-0.03363703563809395,
0.053878750652074814,
0.0651077851653099,
0.05685335770249367,
-0.00802437774837017,
0.024126308038830757,
-0.025978554040193558,
-0.0059456368908286095,
0.03942377120256424,
0.052410587668418884,
-0.029724301770329475,
-0.013131697662174702,
0.03632586449384689,
0.020527798682451248,
0.11364205181598663,
-0.015751665458083153,
-0.022311022505164146,
0.05737617239356041,
0.01019893679767847,
-0.02466540038585663,
0.0018492856761440635,
-0.021233489736914635,
-0.10152481496334076,
-2.722569996450185e-33,
0.01990736834704876,
0.043275680392980576,
0.011492245830595493,
0.08440658450126648,
0.04066988080739975,
0.017824456095695496,
-0.014707797206938267,
-0.0074896011501550674,
-0.009640157222747803,
-0.05137760564684868,
-0.040926024317741394,
-0.05343395844101906,
0.0517093725502491,
0.10166644304990768,
-0.0712587982416153,
-0.01059645228087902,
-0.05194772779941559,
0.011574380099773407,
0.058974724262952805,
-0.11785106360912323,
-0.07195767760276794,
-0.05042233690619469,
-0.02742830663919449,
-0.029503822326660156,
-0.044816676527261734,
-0.057311881333589554,
0.012304051779210567,
0.05092313140630722,
0.11171819269657135,
-0.015392599627375603,
-0.01397755742073059,
0.00985770858824253,
0.00962693803012371,
-0.014386693947017193,
0.08334672451019287,
0.07076653093099594,
0.054001666605472565,
-0.06502925604581833,
0.06621038913726807,
0.09135130792856216,
-0.040516447275877,
-0.022759689018130302,
-0.07528886944055557,
-0.058824021369218826,
-0.05469861626625061,
-0.004759833682328463,
-0.06617844104766846,
-0.02409082092344761,
-0.0933116152882576,
0.0016040313057601452,
0.048683345317840576,
0.017251823097467422,
-0.027045128867030144,
0.0410350002348423,
-0.04828833416104317,
0.058167509734630585,
-0.09503182768821716,
-0.07259683310985565,
-0.03733545541763306,
0.009757633320987225,
-0.02504006214439869,
-0.09834598004817963,
-0.00018491630908101797,
0.02306753769516945,
0.02330329269170761,
-0.007921361364424229,
-0.012521828524768353,
-0.0578964538872242,
-0.054339632391929626,
0.02409442886710167,
0.030263179913163185,
-0.007330549415200949,
0.05884701386094093,
-0.09609924256801605,
-0.011156254447996616,
-0.05542243644595146,
-0.09777435660362244,
0.039862800389528275,
-0.05339193344116211,
0.143315851688385,
0.03332075476646423,
0.054747793823480606,
-0.09313619881868362,
0.023713838309049606,
0.02568533830344677,
-0.0746978297829628,
0.0461207814514637,
-0.0448426753282547,
0.03134290501475334,
-0.06775899231433868,
0.08187950402498245,
-0.06381361186504364,
0.021674567833542824,
0.004680923651903868,
0.0542183555662632,
-7.509687703666269e-36,
-0.06618332117795944,
-0.041742175817489624,
0.027406400069594383,
-0.016076231375336647,
0.027914009988307953,
-0.03122127242386341,
0.10236739367246628,
-0.08980804681777954,
0.011240633204579353,
0.04340682551264763,
0.08445993065834045,
-0.003495016135275364,
-0.05110180377960205,
-0.04345636069774628,
0.0011209946824237704,
-0.02945070154964924,
-0.013907438144087791,
0.012284565716981888,
0.01119399257004261,
-0.03411303833127022,
-0.03784242272377014,
0.001154308207333088,
-0.02776235342025757,
0.06533267349004745,
0.06402267515659332,
-0.014273779466748238,
-0.004681664053350687,
0.09155003726482391,
0.025390448048710823,
0.0556965246796608,
-0.06878721714019775,
0.00913882628083229,
-0.112459696829319,
0.010688100010156631,
-0.006603457499295473,
0.07710040360689163,
0.05340198799967766,
-0.004945097025483847,
-0.007009596563875675,
-0.058322563767433167,
-0.03470237925648689,
0.024431899189949036,
-0.08052168786525726,
-0.02454492822289467,
0.01870282180607319,
0.09637270122766495,
0.04428146779537201,
0.062179286032915115,
0.029901260510087013,
-0.04493604972958565,
0.04939046874642372,
0.033668212592601776,
-0.009952107444405556,
-0.035501107573509216,
0.04493727162480354,
-0.03733281418681145,
0.08199065923690796,
-0.01758289523422718,
-0.02051272988319397,
0.007335147820413113,
-0.04980729520320892,
-0.00865880772471428,
-0.036130934953689575,
0.11103025823831558,
-0.015536515042185783,
0.06252066045999527,
0.020747877657413483,
0.0760379284620285,
-0.013540714979171753,
-0.01992122083902359,
0.05116637796163559,
0.02617109753191471,
0.05798216909170151,
0.027845218777656555,
-0.043028898537158966,
-0.03718293085694313,
-0.06113174185156822,
-0.001476453267969191,
-0.0504000298678875,
0.011787165887653828,
0.03162387013435364,
-0.07761918753385544,
0.011416659690439701,
-0.04912183806300163,
0.025184698402881622,
-0.012744772247970104,
0.01279640942811966,
0.06693821400403976,
-0.06336161494255066,
-0.013517710380256176,
-0.06648735702037811,
-0.0078092310577631,
-0.08970388025045395,
0.04796188324689865,
0.03463578224182129,
-3.150333327539556e-8,
-0.016085311770439148,
-0.09476040303707123,
-0.006868095137178898,
-0.052373066544532776,
-0.02100430801510811,
0.10577329993247986,
-0.021508604288101196,
0.05097566917538643,
0.0575537346303463,
0.026263855397701263,
0.010018950328230858,
-0.00038682002923451364,
-0.041893333196640015,
0.08025459200143814,
0.06153326481580734,
-0.023175731301307678,
0.028905440121889114,
0.014019838534295559,
0.026201557368040085,
-0.12773309648036957,
-0.045414961874485016,
0.034839481115341187,
-0.034339677542448044,
0.06258708983659744,
0.06790532171726227,
-0.027759961783885956,
0.026960322633385658,
0.06665146350860596,
0.03510814905166626,
-0.105291448533535,
0.011004399508237839,
-0.007113173138350248,
0.0381702296435833,
0.017908994108438492,
0.014304179698228836,
-0.0030689267441630363,
0.05539233237504959,
-0.02230902947485447,
-0.025006256997585297,
0.04645978659391403,
-0.025023384019732475,
0.07423799484968185,
-0.0429561473429203,
-0.02245703712105751,
-0.0031248247250914574,
0.019814325496554375,
-0.019566895440220833,
0.11537986993789673,
-0.025635194033384323,
-0.07899554818868637,
-0.011158659122884274,
-0.016213929280638695,
0.005219975486397743,
0.026364022865891457,
-0.05348464101552963,
0.02797692082822323,
-0.09850893914699554,
-0.004097622819244862,
0.009297958575189114,
0.07047286629676819,
0.01382549200206995,
0.03786173835396767,
0.04298707842826843,
-0.11487983167171478
] |
PMID:33085037 | In this review we will discuss the role of the epigenetic machinery in controlling the expression of both SSTRs and the neuropeptide SST. | [
-0.0858239009976387,
-0.053941644728183746,
-0.125947505235672,
0.031125683337450027,
0.011192554607987404,
0.13101725280284882,
-0.03465557470917702,
0.029692785814404488,
-0.000058852016081800684,
-0.023914512246847153,
0.04576259106397629,
-0.012167196720838547,
-0.025398142635822296,
0.005992377642542124,
0.08383700251579285,
0.025169678032398224,
-0.057063546031713486,
0.014503290876746178,
0.06796455383300781,
-0.03164064139127731,
0.015549284406006336,
0.061865322291851044,
0.027695873752236366,
-0.0190731268376112,
-0.012323817238211632,
0.003704328555613756,
0.005106611177325249,
-0.03665224835276604,
0.029684392735362053,
0.017528627067804337,
0.026225443929433823,
-0.028271084651350975,
-0.07401738315820694,
0.015714310109615326,
0.010809015482664108,
-0.03952808678150177,
-0.09033572673797607,
-0.006074363365769386,
-0.014817648567259312,
-0.040914278477430344,
0.08902579545974731,
-0.032929323613643646,
-0.10658501088619232,
-0.0231807678937912,
-0.02524690330028534,
-0.02831253595650196,
0.004716411232948303,
-0.07363321632146835,
-0.07582848519086838,
0.003574259113520384,
-0.02413611300289631,
-0.08409799635410309,
0.051049795001745224,
0.09879300743341446,
0.033868350088596344,
0.055639706552028656,
0.033141374588012695,
-0.015726126730442047,
0.006094201002269983,
0.0059080785140395164,
-0.05770794674754143,
-0.05220862850546837,
-0.00529983127489686,
-0.0622415728867054,
0.09726732224225998,
0.04252178221940994,
-0.019975658506155014,
-0.015299452468752861,
-0.06745094060897827,
-0.036189161241054535,
0.041706543415784836,
-0.012113505974411964,
-0.010901108384132385,
0.08643913269042969,
0.03998134285211563,
-0.016921792179346085,
-0.032694797962903976,
-0.018469881266355515,
0.036100950092077255,
0.016226384788751602,
-0.012434041127562523,
0.055340759456157684,
0.041394107043743134,
0.13128115236759186,
0.01953772082924843,
0.04497779160737991,
0.0035790149122476578,
0.040336381644010544,
-0.01037710439413786,
0.12448909133672714,
0.012395299971103668,
-0.10244497656822205,
0.042791880667209625,
-0.03416668251156807,
-0.04324423894286156,
-0.0071571157313883305,
-0.09251545369625092,
-0.04036108776926994,
0.0009556106524541974,
-0.0912453755736351,
-0.008036290295422077,
0.07731977105140686,
-0.11727248877286911,
0.02451273798942566,
0.00726214749738574,
0.05923490971326828,
0.09945856034755707,
-0.023313166573643684,
-0.036517638713121414,
-0.013108301907777786,
-0.01046078186482191,
-0.047970715910196304,
0.053891170769929886,
0.05358371138572693,
-0.04150731489062309,
-0.012272526510059834,
-0.016915351152420044,
0.08122637867927551,
0.04550061747431755,
-0.09558731317520142,
0.040467169135808945,
0.05487992987036705,
-0.018444988876581192,
0.011552094481885433,
-0.025768278166651726,
-0.021959610283374786,
-0.11720826476812363,
-1.7606255002898747e-33,
0.07885511964559555,
0.027307746931910515,
-0.0390377976000309,
0.006259939167648554,
0.024572407826781273,
0.01875334233045578,
-0.03160307928919792,
-0.033198244869709015,
0.09774589538574219,
0.0218865517526865,
-0.08849158138036728,
-0.14300256967544556,
-0.008823390118777752,
0.0386955626308918,
-0.08090568333864212,
-0.0681271106004715,
-0.11045583337545395,
0.0010775976115837693,
0.04841236397624016,
-0.10953716933727264,
0.006355132441967726,
0.05160815641283989,
0.027498165145516396,
-0.045336075127124786,
-0.004944874905049801,
-0.05516553670167923,
-0.02410380356013775,
0.07010390609502792,
0.01273591909557581,
0.006821485701948404,
-0.047331422567367554,
0.0202668197453022,
-0.013148140162229538,
0.0497005470097065,
0.10267714411020279,
0.030186470597982407,
0.09846237301826477,
-0.07021871954202652,
0.07345281541347504,
0.10561797022819519,
0.07494650781154633,
0.016822103410959244,
-0.04373946040868759,
-0.028109420090913773,
0.006227195728570223,
0.021272873505949974,
0.00890073087066412,
-0.0024163699708878994,
0.0010951607255265117,
0.061550725251436234,
-0.014990651980042458,
0.0014534055953845382,
0.02311336249113083,
0.02495337650179863,
-0.04552231729030609,
0.04017147049307823,
-0.04797549918293953,
-0.047800883650779724,
-0.017495878040790558,
-0.003103390336036682,
-0.043350256979465485,
-0.10873325169086456,
0.018614115193486214,
0.002915523014962673,
0.046153172850608826,
0.02081787958741188,
-0.025921307504177094,
-0.043364230543375015,
-0.05787421390414238,
-0.05747351050376892,
0.03755859658122063,
0.00444146990776062,
0.1007862314581871,
-0.038874100893735886,
0.030528103932738304,
-0.026677614077925682,
-0.017984585836529732,
0.12559419870376587,
-0.040566567331552505,
0.03638860583305359,
-0.018572093918919563,
0.024445505812764168,
-0.10494037717580795,
-0.020935557782649994,
0.08361892402172089,
-0.0495033860206604,
0.06073352321982384,
-0.08393674343824387,
-0.007802753243595362,
-0.061082154512405396,
0.05952814221382141,
-0.04744083434343338,
0.04712246358394623,
0.02267460711300373,
-0.026717759668827057,
6.474258297409412e-34,
-0.09347974509000778,
-0.0166910570114851,
0.08710239827632904,
-0.012461762875318527,
-0.050261300057172775,
-0.03677913174033165,
0.07617423683404922,
0.0177035853266716,
0.0023220940493047237,
0.021915769204497337,
0.06331812590360641,
0.010724535211920738,
-0.009192390367388725,
-0.08503607660531998,
0.02342391386628151,
-0.035706743597984314,
0.0026481293607503176,
0.03355829790234566,
0.04982960224151611,
-0.058395396918058395,
0.009485897608101368,
0.010298112407326698,
-0.027737822383642197,
0.07334309071302414,
0.10898672789335251,
0.07814845442771912,
0.022123705595731735,
0.11351470649242401,
0.09271370619535446,
0.03147229179739952,
-0.026774097234010696,
0.07202795892953873,
-0.0545525848865509,
-0.01653323508799076,
0.004935224540531635,
0.04384738206863403,
0.01968206651508808,
0.06083260476589203,
-0.049645114690065384,
-0.08239109069108963,
-0.01245700754225254,
0.030112074688076973,
-0.0018199117621406913,
0.04868476837873459,
0.05936005339026451,
0.03294594585895538,
0.04165789857506752,
0.0726005882024765,
0.03259440138936043,
-0.05171440169215202,
0.026007086038589478,
-0.031573522835969925,
0.012436067685484886,
-0.030919885262846947,
-0.0006366323796100914,
-0.08721240609884262,
0.029267869889736176,
0.004353463649749756,
-0.0492701530456543,
-0.019885608926415443,
0.021248776465654373,
0.06351938843727112,
-0.00914057157933712,
0.03402705490589142,
-0.020758630707859993,
0.004633008968085051,
0.056982073932886124,
-0.007700410205870867,
0.08938529342412949,
-0.034173280000686646,
-0.01122262328863144,
0.014387449249625206,
0.09585709869861603,
-0.06641244143247604,
-0.009584872052073479,
-0.06533931195735931,
-0.12436023354530334,
0.04396720975637436,
0.034937482327222824,
-0.02315676212310791,
0.018530257046222687,
0.022593634203076363,
-0.053462062031030655,
-0.06770370155572891,
0.017959419637918472,
0.04801640659570694,
-0.05420127138495445,
0.07168088853359222,
0.023812098428606987,
0.029724204912781715,
-0.10469203442335129,
0.028121499344706535,
0.01822115294635296,
0.06604067236185074,
-0.029855720698833466,
-2.7762002474673864e-8,
0.09772589057683945,
-0.06039697304368019,
0.0005384506075643003,
-0.04471419379115105,
0.006116241682320833,
-0.07290768623352051,
-0.03232211247086525,
-0.043319135904312134,
0.017407076433300972,
-0.026893828064203262,
-0.005989559460431337,
0.016300978139042854,
-0.009871723130345345,
-0.02623939886689186,
0.02590395323932171,
-0.028375642374157906,
-0.046725839376449585,
0.02013331465423107,
0.017980795353651047,
-0.07983403652906418,
0.013712442480027676,
-0.0538739450275898,
0.014566997066140175,
0.07063432037830353,
0.03999108821153641,
0.018012825399637222,
-0.006046437658369541,
0.03476865962147713,
0.059283941984176636,
-0.08552875369787216,
0.0764637291431427,
-0.048383284360170364,
0.003583248471841216,
0.03625382483005524,
0.01748092658817768,
-0.028870243579149246,
0.03206877410411835,
-0.03136514127254486,
0.0954374223947525,
0.057824522256851196,
-0.03822361305356026,
0.013008677400648594,
-0.0027323653921484947,
0.017082015052437782,
-0.0546804778277874,
0.006814845371991396,
-0.0177905410528183,
0.0451035350561142,
-0.04523918405175209,
-0.07961495965719223,
-0.06241759657859802,
-0.03727731108665466,
-0.02759135514497757,
0.01814204454421997,
-0.07052262127399445,
0.006753925699740648,
0.01856970228254795,
0.028284596279263496,
0.02401849441230297,
0.02202940173447132,
-0.018128279596567154,
0.030646584928035736,
0.06306152045726776,
-0.034669239073991776
] |
PMID:33085037 | Particular attention will be given to the epigenetic regulation of these proteins in NETs, whereas the involvement of the epigenetic machinery in other types of cancer will be discussed as well. | [
0.013126444071531296,
-0.062498029321432114,
-0.10889750719070435,
-0.07253415137529373,
0.015886858105659485,
0.06380315124988556,
0.05087278038263321,
-0.03293528035283089,
0.06575863808393478,
-0.0358005091547966,
0.06580043584108353,
0.01642857864499092,
-0.06167520210146904,
-0.012821866199374199,
0.04365742206573486,
0.06623668223619461,
-0.12202141433954239,
-0.017045728862285614,
-0.09162499755620956,
-0.013562100008130074,
0.01118562277406454,
0.020197167992591858,
0.02941177599132061,
0.0014665136113762856,
-0.051297321915626526,
-0.060473885387182236,
0.032404862344264984,
0.059231918305158615,
0.03357154503464699,
-0.0038562570698559284,
-0.01727207750082016,
-0.012757849879562855,
-0.040974315255880356,
0.0293287206441164,
-0.038342464715242386,
0.03182804211974144,
-0.030066709965467453,
0.06373124569654465,
-0.04078591242432594,
-0.026583200320601463,
0.058335546404123306,
-0.041540708392858505,
-0.06220327690243721,
0.01841222681105137,
-0.007015329319983721,
-0.07425402104854584,
-0.006912925746291876,
-0.1103096529841423,
-0.018608232960104942,
0.04520377144217491,
-0.01861397922039032,
-0.05426324903964996,
-0.012938419356942177,
-0.005542986560612917,
0.06868493556976318,
0.05852731317281723,
-0.026478761807084084,
0.020687676966190338,
-0.009854252450168133,
-0.04208824783563614,
-0.0034527163952589035,
-0.10783008486032486,
-0.03947930783033371,
0.018236175179481506,
0.07811815291643143,
-0.024279486387968063,
0.0772288516163826,
-0.05919825658202171,
-0.038521602749824524,
-0.05123848095536232,
0.044930681586265564,
-0.012274005450308323,
-0.005695569794625044,
0.06374712288379669,
0.04303372651338577,
-0.0012880099238827825,
0.018404118716716766,
0.004983054473996162,
-0.038056690245866776,
-0.0013891468988731503,
-0.018546171486377716,
0.09801872819662094,
0.14395229518413544,
-0.02051469497382641,
-0.0655670240521431,
0.04934101551771164,
-0.018118543550372124,
0.05690497159957886,
-0.020806532353162766,
0.06027516722679138,
-0.048967394977808,
-0.05337235704064369,
0.08034771680831909,
0.01823345571756363,
-0.03219973295927048,
0.05425574257969856,
0.021993789821863174,
-0.09333010762929916,
0.01431098859757185,
-0.040977947413921356,
0.01702212542295456,
-0.05299341306090355,
-0.11126488447189331,
0.031184419989585876,
0.002839198801666498,
0.08418009430170059,
-0.016163896769285202,
0.03321342170238495,
-0.09276140481233597,
-0.034589603543281555,
-0.0019421476172283292,
-0.0049429177306592464,
0.11011704802513123,
0.037240903824567795,
-0.018394246697425842,
-0.019390223547816277,
-0.00844330620020628,
-0.0034109216649085283,
0.08907342702150345,
0.01064379047602415,
-0.0626620352268219,
0.006522028706967831,
0.05467906966805458,
-0.00844945665448904,
0.00967167317867279,
-0.038344547152519226,
-0.13936418294906616,
-5.404206708210846e-34,
0.055850252509117126,
0.019490884616971016,
0.004726497922092676,
0.009416526183485985,
0.07735027372837067,
0.03464632108807564,
0.006037320476025343,
-0.025887764990329742,
0.05983683094382286,
-0.04716550186276436,
-0.03888081759214401,
-0.006936527322977781,
0.008934831246733665,
0.05083948373794556,
-0.059874337166547775,
0.0003835003881249577,
-0.047057121992111206,
0.04713141918182373,
-0.03419620543718338,
-0.10885687172412872,
-0.11057121306657791,
-0.009987195022404194,
-0.012912910431623459,
-0.05010217800736427,
0.024326832965016365,
-0.04326021671295166,
-0.016858046874403954,
0.024682864546775818,
0.00900779478251934,
0.009821918793022633,
-0.08507170528173447,
0.011531485244631767,
0.026378219947218895,
0.04049774259328842,
0.01765481010079384,
0.0938800722360611,
0.04071537405252457,
-0.04299391806125641,
0.04939627647399902,
0.03623088821768761,
0.017283970490098,
-0.02463695965707302,
-0.06892160326242447,
-0.011331294663250446,
-0.04338032007217407,
-0.08107323944568634,
-0.06662435829639435,
-0.024390529841184616,
-0.10057970136404037,
0.008553826250135899,
0.030067486688494682,
-0.0713617354631424,
0.015065507963299751,
-0.02073178067803383,
0.0004022720968350768,
-0.024892127141356468,
-0.08992592245340347,
0.0381857231259346,
-0.05077715218067169,
0.019673509523272514,
0.03192451223731041,
-0.08841600269079208,
-0.0037796786054968834,
0.07936597615480423,
0.04014427214860916,
0.042152103036642075,
-0.06440151482820511,
-0.05716613307595253,
-0.028244875371456146,
-0.011248037219047546,
-0.03344012051820755,
0.013848558999598026,
0.10258439183235168,
-0.010030479170382023,
-0.024935565888881683,
-0.013580934144556522,
-0.09639555215835571,
0.035930462181568146,
-0.04835077002644539,
0.2125132977962494,
0.057946544140577316,
-0.0072672707028687,
-0.15626545250415802,
0.012984457425773144,
-0.0399886853992939,
-0.017296021804213524,
0.09552109241485596,
-0.08590177446603775,
0.05200236290693283,
0.008062181994318962,
0.052075278013944626,
-0.03839539736509323,
0.06107490882277489,
0.013654095120728016,
0.005212543997913599,
-3.4734043397394514e-33,
-0.042695753276348114,
0.002791304374113679,
0.07892562448978424,
-0.025650475174188614,
-0.006214110646396875,
-0.005654753651469946,
0.10013768821954727,
-0.07212144136428833,
-0.059318557381629944,
-0.011107108555734158,
0.0559283085167408,
0.03223017603158951,
-0.09324535727500916,
-0.06150239333510399,
-0.09843090176582336,
-0.039127547293901443,
0.003592824097722769,
0.03761513903737068,
0.0024707098491489887,
-0.03354717418551445,
-0.040190234780311584,
-0.0004157352668698877,
-0.08455905318260193,
0.05226828157901764,
-0.037052933126688004,
0.02559650130569935,
0.01760121062397957,
0.04540039226412773,
-0.013636335730552673,
0.006433046888560057,
-0.03188062831759453,
0.016240207478404045,
-0.041335802525281906,
0.07404200732707977,
0.04075680300593376,
0.0278247632086277,
0.02965524233877659,
-0.07617611438035965,
-0.014341127127408981,
-0.045592330396175385,
0.006633991841226816,
0.052374206483364105,
-0.05540047585964203,
0.0036399709060788155,
0.03726961463689804,
0.10958389937877655,
0.0382385291159153,
0.0036785476841032505,
-0.02708779275417328,
-0.0025798159185796976,
0.01228394452482462,
0.07488600164651871,
-0.033173155039548874,
0.02402692474424839,
-0.030618932098150253,
0.031498875468969345,
0.03529007360339165,
-0.03791259974241257,
0.0013428963720798492,
0.038190994411706924,
-0.06016824021935463,
-0.0430038720369339,
-0.026690807193517685,
0.052379608154296875,
-0.032926883548498154,
0.06673039495944977,
0.04143097251653671,
-0.010874203406274319,
0.10018790513277054,
-0.010724697262048721,
0.03582911193370819,
-0.018618734553456306,
0.030451716855168343,
0.006013768259435892,
-0.050376083701848984,
-0.008378983475267887,
-0.02542877569794655,
-0.016902321949601173,
-0.024423543363809586,
0.011377919465303421,
-0.02145037055015564,
-0.02247639000415802,
-0.03030318208038807,
-0.04305838420987129,
0.043662797659635544,
0.05223431438207626,
-0.0037075041327625513,
0.008082274347543716,
0.002285275375470519,
-0.0766536220908165,
-0.002993025816977024,
0.01762276329100132,
-0.050563134253025055,
0.03583787381649017,
0.0019590144511312246,
-3.338620402359993e-8,
0.04697253182530403,
-0.03758690878748894,
0.028278766199946404,
-0.07810313999652863,
0.02439213916659355,
0.048785556107759476,
-0.015235593542456627,
0.07259196788072586,
0.021275483071804047,
0.05472211167216301,
-0.019157130271196365,
0.008715054951608181,
-0.07831887155771255,
0.033877886831760406,
0.04394548013806343,
0.05027054250240326,
0.034040432423353195,
-0.0030772429890930653,
0.024958183988928795,
-0.07436151802539825,
-0.014867601916193962,
-0.010626780800521374,
-0.006748452316969633,
0.10647180676460266,
-0.04481039568781853,
-0.04961312934756279,
-0.040916427969932556,
0.14574863016605377,
-0.011539940722286701,
-0.01309636514633894,
0.05051663517951965,
-0.028282687067985535,
0.010851209051907063,
0.051765959709882736,
-0.07268328964710236,
0.04448133707046509,
0.06467512249946594,
-0.07359515130519867,
0.011053350754082203,
0.08176612108945847,
0.0964210107922554,
0.001439615967683494,
-0.06228523701429367,
0.020202668383717537,
0.037713054567575455,
0.0012523966142907739,
0.022742899134755135,
0.06421542912721634,
-0.08732093870639801,
-0.0814114660024643,
-0.03636966645717621,
0.024522412568330765,
0.026461439207196236,
-0.04229314625263214,
-0.048208046704530716,
0.02874263934791088,
-0.02003457397222519,
0.02564520202577114,
-0.0031870612874627113,
0.07375932484865189,
0.01437944546341896,
0.03616610914468765,
0.055893007665872574,
-0.1368526816368103
] |
PMID:33085037 | In addition, we will discuss the possibility to target enzymes involved in the epigenetic machinery to modify the expression of the SST-system, thereby possibly improving therapeutic options. | [
-0.09225798398256302,
-0.027080003172159195,
-0.11127092689275742,
-0.017456261441111565,
0.016821984201669693,
0.0974811241030693,
-0.07924506813287735,
0.060267020016908646,
-0.04546814784407616,
0.0014978996478021145,
0.003961223177611828,
0.01209588535130024,
-0.08353350311517715,
0.05649362877011299,
0.1071469634771347,
0.06870755553245544,
-0.08672978729009628,
0.05219762772321701,
0.029324376955628395,
-0.01505586039274931,
-0.005345942452549934,
0.0669214054942131,
0.05282672494649887,
-0.00355917913839221,
-0.03091984987258911,
-0.044744137674570084,
0.04524562880396843,
-0.031777188181877136,
-0.03712451457977295,
-0.02092658542096615,
-0.015051128342747688,
0.002010253258049488,
0.026533538475632668,
-0.012979051098227501,
-0.0346076674759388,
0.02002418227493763,
-0.007015335373580456,
-0.006661309394985437,
0.020044906064867973,
-0.07081091403961182,
0.0752866193652153,
-0.06575750559568405,
-0.11915303021669388,
-0.021469656378030777,
-0.05876154825091362,
-0.11806122958660126,
0.009947530925273895,
-0.09136269241571426,
-0.06588871777057648,
0.012512952089309692,
-0.06817008554935455,
-0.08473076671361923,
-0.0039359815418720245,
0.03888756036758423,
0.020739218220114708,
0.03209502249956131,
0.0048706806264817715,
-0.032949820160865784,
-0.04192391037940979,
-0.033123839646577835,
0.007841399870812893,
-0.06985017657279968,
-0.05361256003379822,
-0.0009599014883860946,
0.10818667709827423,
-0.03511222451925278,
0.0636085793375969,
0.010238484479486942,
-0.06559917330741882,
-0.016476133838295937,
0.0361880399286747,
-0.045364342629909515,
-0.03187299892306328,
0.05523496866226196,
0.00790143571794033,
0.001681973342783749,
0.00221250974573195,
-0.025209760293364525,
0.003913892433047295,
0.03981836140155792,
0.0017576569225639105,
0.021441254764795303,
0.06837479770183563,
0.08323167264461517,
0.020788569003343582,
0.054928168654441833,
-0.014556137844920158,
0.0356626957654953,
0.03135513514280319,
0.09674685448408127,
-0.007886129431426525,
-0.10044779628515244,
0.05404025316238403,
-0.008820305578410625,
-0.04304216057062149,
0.07030092179775238,
-0.058963097631931305,
-0.05415560305118561,
0.01984783075749874,
-0.055812932550907135,
0.005055559333413839,
0.07485804706811905,
-0.10565943270921707,
-0.005354269873350859,
0.009275603108108044,
0.042195454239845276,
0.04609670117497444,
0.008067574352025986,
-0.046208642423152924,
-0.04937119781970978,
0.027015745639801025,
-0.05716913565993309,
0.04068765789270401,
0.041573744267225266,
-0.039273034781217575,
0.05297159403562546,
-0.026660870760679245,
0.01555204764008522,
0.04206167533993721,
-0.04907507076859474,
0.018725328147411346,
0.05784078314900398,
0.00590016832575202,
0.04241350665688515,
0.007192210294306278,
0.06097552925348282,
-0.15564079582691193,
-3.10845448611141e-33,
0.0643165335059166,
0.03793922811746597,
0.02738739177584648,
0.04500622674822807,
0.015183673240244389,
0.051965098828077316,
-0.039415694773197174,
-0.030248824506998062,
0.048907987773418427,
-0.05793026462197304,
-0.04488604888319969,
-0.09546621888875961,
0.057665713131427765,
0.06689450144767761,
-0.0822201520204544,
-0.05842192843556404,
-0.0887601226568222,
0.01284752320498228,
0.037232477217912674,
-0.10297975689172745,
0.008611906319856644,
0.037066999822854996,
-0.0632568895816803,
-0.01856008544564247,
-0.021463211625814438,
-0.033135946840047836,
0.025478942319750786,
0.04348914697766304,
0.050186652690172195,
0.002171732485294342,
-0.08821948617696762,
-0.015796910971403122,
-0.010461960919201374,
0.04013986513018608,
0.06454017013311386,
0.061880871653556824,
0.07174656540155411,
-0.038766346871852875,
0.05284235253930092,
0.07850377261638641,
0.07882002741098404,
0.01974346674978733,
-0.037997402250766754,
-0.03510023653507233,
0.01407958846539259,
-0.001791930990293622,
-0.009134680964052677,
0.006100376136600971,
-0.03841106966137886,
0.07151506096124649,
-0.01731032133102417,
0.00085351342568174,
0.016308680176734924,
0.0033953965175896883,
-0.03194046393036842,
0.058023884892463684,
-0.07673327624797821,
-0.05684744194149971,
0.020697705447673798,
0.00719581451267004,
-0.010018209926784039,
-0.11913537979125977,
0.01604537107050419,
0.05811532959342003,
0.013853618875145912,
0.006918831262737513,
-0.030137300491333008,
-0.08888707309961319,
-0.09105464071035385,
0.03422247990965843,
-0.013163389638066292,
-0.03853188827633858,
0.10687442123889923,
-0.025965195149183273,
0.029325086623430252,
-0.03833591565489769,
-0.020455896854400635,
0.08069673925638199,
-0.013727106153964996,
0.024239948019385338,
0.026727449148893356,
-0.006100385449826717,
-0.1378033310174942,
0.01156583335250616,
0.07241111248731613,
-0.07095768302679062,
-0.0017242326866835356,
-0.08900236338376999,
-0.06028129160404205,
-0.04062963277101517,
0.07313155382871628,
-0.07257936894893646,
0.035491324961185455,
0.068849578499794,
-0.032273899763822556,
3.897769830836294e-34,
-0.004878220614045858,
-0.044910870492458344,
0.08814399689435959,
-0.01573558896780014,
0.0012260657967999578,
-0.0010936774779111147,
0.09166793525218964,
-0.026309749111533165,
0.02745230682194233,
0.039278481155633926,
0.05603744089603424,
-0.0029503849800676107,
-0.013139755465090275,
-0.08348587900400162,
-0.06192810460925102,
-0.005425977986305952,
-0.014581252820789814,
-0.0010623587295413017,
0.002708585001528263,
0.012001038528978825,
0.01712689734995365,
0.08215534687042236,
-0.023213719949126244,
0.08572214096784592,
0.10584105551242828,
0.05382663011550903,
0.05647682026028633,
0.08876688033342361,
0.05489997938275337,
0.009864307008683681,
-0.06242574006319046,
0.009908676147460938,
-0.07325170189142227,
0.003538173623383045,
0.02033288963139057,
0.09552168846130371,
0.10832984000444412,
0.019482474774122238,
-0.0034789349883794785,
-0.03215284273028374,
0.004640699364244938,
0.020133167505264282,
-0.06152183189988136,
0.07623568922281265,
0.044207438826560974,
0.10085833817720413,
0.0211643073707819,
0.08729888498783112,
0.01167882326990366,
-0.05524134635925293,
0.045672859996557236,
-0.017574556171894073,
-0.02238648571074009,
-0.0024209339171648026,
0.03481306508183479,
-0.06616751849651337,
0.06390264630317688,
-0.06298159062862396,
-0.029137272387742996,
-0.02623000368475914,
-0.061064817011356354,
0.016064418479800224,
0.01676785945892334,
-0.004486034158617258,
-0.02522983029484749,
0.017330121248960495,
-0.018609991297125816,
0.029417116194963455,
0.023112118244171143,
-0.021814126521348953,
-0.004895923659205437,
-0.008672310970723629,
0.04313887655735016,
-0.01642569713294506,
-0.024017589166760445,
-0.06661580502986908,
-0.06358122825622559,
-0.05494994297623634,
-0.003464089473709464,
-0.020399877801537514,
0.00826778169721365,
-0.04385805130004883,
-0.03022594191133976,
-0.07498468458652496,
0.07327986508607864,
-0.022021813318133354,
0.004715725313872099,
0.08349837362766266,
0.013973418623209,
0.008323541842401028,
-0.12411768734455109,
-0.007103137671947479,
-0.006504004821181297,
0.06623930484056473,
0.027521027252078056,
-3.129505898868956e-8,
0.09667462110519409,
-0.08640209585428238,
-0.004275855142623186,
-0.042897190898656845,
0.0018760970560833812,
0.0074936021119356155,
-0.07300878316164017,
0.033415455371141434,
0.02912049926817417,
0.02211587503552437,
-0.0511021688580513,
0.06577250361442566,
-0.00382649851962924,
0.06769175827503204,
0.04692428559064865,
-0.022327153012156487,
-0.05133999511599541,
0.02519020438194275,
-0.032460566610097885,
-0.09957131743431091,
-0.010382925160229206,
0.0017154404195025563,
-0.002180437557399273,
0.08426427841186523,
0.03134267404675484,
0.008287603035569191,
-0.024713866412639618,
0.04191656783223152,
0.044930461794137955,
-0.089717335999012,
0.03584801033139229,
-0.021325090900063515,
0.00412563793361187,
0.09872167557477951,
-0.06003214791417122,
-0.04697365313768387,
0.02476428635418415,
-0.03197431191802025,
0.0374215766787529,
0.08762869238853455,
-0.032337069511413574,
0.012586080469191074,
-0.07415911555290222,
0.02673523500561714,
-0.021557550877332687,
-0.04761182516813278,
-0.0157365333288908,
0.0672377496957779,
-0.036814913153648376,
-0.026911279186606407,
0.007115466054528952,
-0.0345955491065979,
-0.02254740707576275,
-0.019816678017377853,
-0.023910041898489,
0.08440835028886795,
-0.004025377798825502,
0.004303813446313143,
-0.020847218111157417,
0.034356843680143356,
0.06375504285097122,
0.01862775720655918,
0.10813304781913757,
-0.0844169482588768
] |
PMID:25838188 | We previously developed a multigene expression model of tumor radiation sensitivity index (RSI) with clinical validation in multiple independent cohorts (breast, rectal, esophageal, and head and neck patients). | [
0.08728104829788208,
-0.05096745491027832,
-0.0071534523740410805,
0.000496820081025362,
0.027881059795618057,
-0.020072951912879944,
0.017686406150460243,
0.06927355378866196,
0.021857615560293198,
-0.050529271364212036,
-0.04686953127384186,
-0.10159117728471756,
0.10781242698431015,
0.04959138482809067,
-0.0424184575676918,
0.007773177698254585,
-0.04157562181353569,
0.039655156433582306,
-0.023155808448791504,
-0.019480280578136444,
-0.0329345166683197,
0.05972336232662201,
0.019971542060375214,
0.00521189346909523,
0.024488424882292747,
-0.109553262591362,
0.011362503282725811,
0.04889481142163277,
-0.05661442503333092,
0.09717215597629547,
0.0821336954832077,
-0.0006628807168453932,
0.012166846543550491,
-0.008084704168140888,
-0.05468571558594704,
0.009119200520217419,
-0.07068203389644623,
-0.025895478203892708,
-0.019063906744122505,
0.05977936089038849,
-0.017050011083483696,
-0.029679344967007637,
-0.023867791518568993,
0.0049034287221729755,
0.06286568939685822,
-0.09043949842453003,
-0.06142047792673111,
-0.054847706109285355,
-0.01581013947725296,
0.04951358959078789,
0.07297554612159729,
-0.026582511141896248,
-0.069271020591259,
0.0635855495929718,
0.012298216111958027,
-0.07711481302976608,
-0.06622178107500076,
-0.07671734690666199,
0.04227400943636894,
0.0015934596303850412,
0.022488361224532127,
-0.1366579681634903,
0.011196141131222248,
0.05803671106696129,
0.08821029216051102,
0.06439238041639328,
0.010766000486910343,
-0.07170340418815613,
-0.02180921658873558,
0.03184658661484718,
-0.05319005995988846,
0.04167909920215607,
-0.053446196019649506,
-0.024118028581142426,
-0.08896492421627045,
-0.04472062736749649,
0.08342090249061584,
0.04215814918279648,
0.051454659551382065,
0.04676521569490433,
-0.05865686386823654,
0.02218899317085743,
-0.0026584165170788765,
-0.08287092298269272,
0.0286263320595026,
-0.020108679309487343,
0.03216206654906273,
0.061732638627290726,
0.021460752934217453,
0.08284839987754822,
0.007031604181975126,
0.06957996636629105,
-0.001396005041897297,
0.036401595920324326,
-0.005394060630351305,
0.018622707575559616,
-0.04760301113128662,
-0.039631035178899765,
0.011193360202014446,
-0.014622559770941734,
-0.03131599724292755,
-0.08017586916685104,
-0.052199408411979675,
0.0672738328576088,
-0.05901727452874184,
-0.07009031623601913,
0.013329179026186466,
-0.09464389085769653,
-0.08506179600954056,
-0.03720555454492569,
-0.004884076304733753,
0.0458369143307209,
0.033249951899051666,
0.0522935651242733,
-0.03183642774820328,
0.04551876708865166,
0.04685533046722412,
0.0009587944950908422,
0.10686437040567398,
-0.035436518490314484,
0.028098762035369873,
-0.03396308049559593,
0.03195643424987793,
-0.05630556121468544,
0.045387446880340576,
-0.0021532271057367325,
-0.05629442632198334,
4.642502899267312e-34,
0.07184037566184998,
0.08995974063873291,
0.01935230754315853,
0.006733473856002092,
-0.023204151540994644,
0.02693813480436802,
-0.06918622553348541,
-0.05708138644695282,
-0.057699054479599,
0.0010051974095404148,
-0.007418456487357616,
0.07425808906555176,
0.06036015972495079,
-0.0332801528275013,
0.03253031149506569,
0.06551460176706314,
-0.008838018402457237,
0.11810804158449173,
-0.04964790493249893,
-0.04681546986103058,
-0.019827179610729218,
-0.059844717383384705,
-0.04330161213874817,
0.010595487430691719,
-0.041811056435108185,
0.0827115997672081,
0.001486879657022655,
0.018802529200911522,
0.015776921063661575,
-0.023595547303557396,
-0.03612029552459717,
-0.016824757680296898,
0.07694791257381439,
0.012721080332994461,
-0.010186733677983284,
0.000720564741641283,
-0.013276517391204834,
0.038325123488903046,
0.10011976212263107,
0.03830698877573013,
0.052500169724226,
0.006552991922944784,
0.07310929149389267,
-0.007887795567512512,
0.017468776553869247,
-0.05406694486737251,
-0.061802808195352554,
-0.13295459747314453,
-0.04202217236161232,
-0.0007953793392516673,
-0.10072185844182968,
-0.03017478436231613,
-0.023778265342116356,
0.0008036067592911422,
0.015809016302227974,
0.022193821147084236,
-0.08214879781007767,
0.08982047438621521,
-0.016150450333952904,
0.06097995862364769,
-0.035783231258392334,
-0.05779952555894852,
0.09848444163799286,
-0.01972164399921894,
0.0542130321264267,
0.02795289270579815,
-0.04280845820903778,
-0.04752087593078613,
-0.0575709231197834,
0.0934382975101471,
0.0006228163838386536,
0.04517581686377525,
0.022201351821422577,
-0.012743436731398106,
0.04250536113977432,
0.009970913641154766,
0.06433852761983871,
0.07248049229383469,
-0.06520266085863113,
0.05856377258896828,
-0.09862959384918213,
0.05036157742142677,
-0.057793840765953064,
-0.0016655842773616314,
0.06709987670183182,
-0.055214256048202515,
-0.05360447242856026,
0.017425745725631714,
-0.05198052525520325,
-0.0007777813007123768,
0.07757765799760818,
0.013040599413216114,
0.013335421681404114,
-0.008354554884135723,
0.03563878312706947,
-3.0708094631973185e-33,
-0.03696856275200844,
-0.00001287791474169353,
0.02327091619372368,
-0.052713792771101,
0.00997200608253479,
-0.017980005592107773,
-0.019534369930624962,
0.02142542228102684,
0.031270790845155716,
-0.012614035047590733,
0.04434949532151222,
0.013360175304114819,
-0.0951760858297348,
-0.0754409208893776,
-0.05050603672862053,
0.02433766797184944,
0.018185637891292572,
-0.01477990485727787,
-0.010832100175321102,
-0.020568722859025,
0.0575033500790596,
0.05637715756893158,
-0.00243017403408885,
0.013810897246003151,
-0.07153483480215073,
-0.0011004299158230424,
0.013505268841981888,
-0.07293204218149185,
-0.0024074064567685127,
-0.058833617717027664,
-0.08523549139499664,
-0.0015762581024318933,
-0.037757132202386856,
0.042574264109134674,
0.060915492475032806,
-0.028602542355656624,
0.023162534460425377,
-0.08151999115943909,
0.01397832203656435,
0.09659124165773392,
-0.01147827971726656,
0.1095142737030983,
-0.019864775240421295,
-0.000050899576308438554,
-0.02524849958717823,
0.01913144253194332,
0.042686983942985535,
-0.0389317125082016,
0.04016299173235893,
-0.05364613234996796,
-0.0710822120308876,
-0.03533331677317619,
-0.05431387200951576,
0.023484287783503532,
-0.02022218145430088,
-0.058273203670978546,
-0.01860780268907547,
-0.04664021357893944,
-0.02048950456082821,
-0.023326115682721138,
0.03219802677631378,
-0.023268140852451324,
-0.04497024789452553,
-0.04513028636574745,
-0.11077661067247391,
0.13276396691799164,
0.010769613087177277,
-0.06688109785318375,
0.01410274114459753,
0.03846653550863266,
-0.006167497485876083,
-0.13439588248729706,
-0.05601070076227188,
0.007969735190272331,
-0.06516524404287338,
-0.0784321278333664,
0.046870820224285126,
0.04460187628865242,
0.02893916703760624,
0.028201213106513023,
-0.04205204173922539,
0.05932877957820892,
-0.01793181709945202,
-0.017001671716570854,
0.048050735145807266,
0.053393907845020294,
-0.03233758360147476,
-0.0015712326858192682,
-0.05458977445960045,
-0.0677698627114296,
-0.028461258858442307,
0.04455244168639183,
0.008337794803082943,
0.02061201073229313,
-0.07993416488170624,
-3.6381603507606997e-8,
-0.01002954225987196,
-0.09819268435239792,
-0.044321753084659576,
-0.09724543243646622,
0.013563008978962898,
0.052209146320819855,
-0.054316241294145584,
-0.03631432354450226,
-0.01900702901184559,
-0.004635957069694996,
0.04712819308042526,
-0.010894237086176872,
-0.012886138632893562,
-0.008590788580477238,
0.009828099980950356,
0.06137934327125549,
0.02202160656452179,
0.09290765970945358,
0.022518815472722054,
-0.013574204407632351,
0.01776174269616604,
0.024771373718976974,
0.07285579293966293,
-0.0030761961825191975,
0.017420975491404533,
0.08560757339000702,
0.01364866178482771,
0.04031649976968765,
0.026003023609519005,
-0.013467643409967422,
0.09450326859951019,
-0.021334560588002205,
-0.006397608667612076,
0.05039733648300171,
-0.03085285611450672,
0.02834113873541355,
0.07180170714855194,
-0.022226350381970406,
0.009905778802931309,
0.13012953102588654,
0.04354273900389671,
-0.061002135276794434,
-0.012775012291967869,
0.03013147972524166,
-0.07221169024705887,
0.07228356599807739,
0.015673315152525902,
-0.07044050842523575,
0.05967013165354729,
-0.060768451541662216,
0.053665488958358765,
-0.07865369319915771,
0.01495455764234066,
0.01109216921031475,
-0.07357364892959595,
0.07180532068014145,
0.081423319876194,
-0.03343705087900162,
0.05338818207383156,
-0.0038584100548177958,
0.08100005984306335,
-0.05230026692152023,
-0.03788915276527405,
-0.0458131767809391
] |
PMID:25838188 | The purpose of this study was to assess differences between RSI scores in primary colon cancer and metastases. | [
0.06270244717597961,
-0.036984145641326904,
-0.08652947843074799,
-0.031605709344148636,
0.01627447083592415,
-0.01651344634592533,
-0.059407416731119156,
0.043149225413799286,
0.055693767964839935,
-0.05346931144595146,
-0.06511043757200241,
0.037183258682489395,
0.007034083362668753,
0.02950236015021801,
-0.055194009095430374,
-0.08507741987705231,
-0.019138295203447342,
-0.019387364387512207,
-0.0341118648648262,
-0.004226229153573513,
0.015150489285588264,
-0.03566661477088928,
0.09067713469266891,
0.01690097711980343,
0.006801629438996315,
-0.037236932665109634,
-0.001649391488172114,
0.02676595374941826,
-0.061585310846567154,
0.11290090531110764,
0.06631700694561005,
-0.02612113393843174,
0.07242751121520996,
-0.005417973734438419,
-0.0016812087269499898,
-0.0034232500474900007,
0.05243278667330742,
0.06909237056970596,
0.03195413202047348,
0.0035835702437907457,
-0.03209144249558449,
-0.05967489629983902,
-0.009694586507976055,
-0.022857075557112694,
0.077242411673069,
-0.0672508031129837,
-0.14324064552783966,
-0.032083600759506226,
0.032287172973155975,
0.055297642946243286,
-0.10101193189620972,
0.0728977620601654,
-0.005703774280846119,
0.07042329013347626,
0.10647743195295334,
-0.04373929277062416,
-0.033182378858327866,
-0.08909531682729721,
0.001329736434854567,
-0.053513266146183014,
-0.012403550557792187,
-0.10453953593969345,
0.013358079828321934,
0.04049919173121452,
0.10804767161607742,
0.014467690140008926,
-0.02075355499982834,
-0.030961083248257637,
0.0025251233018934727,
-0.04175276681780815,
-0.07338607311248779,
0.08348927646875381,
-0.05155916512012482,
0.07811419665813446,
-0.03702331334352493,
-0.008838068693876266,
-0.03861747682094574,
0.05397721752524376,
-0.0678868219256401,
0.056621115654706955,
0.001852003624662757,
0.03174984082579613,
-0.018981758505105972,
0.04459401220083237,
0.02484213002026081,
0.031209155917167664,
0.06696302443742752,
0.009209632873535156,
-0.05473368614912033,
0.03985181823372841,
0.09697800874710083,
0.057374417781829834,
-0.004055207595229149,
0.00367435603402555,
-0.014935605227947235,
-0.034349679946899414,
-0.055409904569387436,
-0.05506698042154312,
0.02891535684466362,
-0.023348020389676094,
-0.10129056125879288,
0.010232187807559967,
-0.07507546991109848,
-0.045675650238990784,
-0.04921277239918709,
0.0038302422035485506,
-0.0340394526720047,
-0.014087037183344364,
-0.033106427639722824,
0.027217082679271698,
0.059469424188137054,
-0.002013676567003131,
0.033393848687410355,
0.050783753395080566,
0.001731916912831366,
0.10838314890861511,
-0.05307537689805031,
0.07010244578123093,
0.07421867549419403,
0.03354678675532341,
-0.03075481951236725,
-0.042486920952796936,
-0.04531417042016983,
0.005842690356075764,
0.09220245480537415,
0.035351771861314774,
-0.03947034105658531,
-1.2606726000282898e-33,
0.0860612541437149,
-0.030961183831095695,
0.043185990303754807,
-0.004445303697139025,
0.020296983420848846,
-0.044737089425325394,
-0.0022909969557076693,
-0.07361460477113724,
0.06362157315015793,
-0.01096801832318306,
0.06907442957162857,
0.02041894942522049,
0.059809740632772446,
-0.05882084742188454,
-0.01093022245913744,
0.056738629937171936,
-0.02375190332531929,
0.02458665892481804,
-0.10443972051143646,
0.009190963581204414,
0.04080519452691078,
-0.012085501104593277,
0.06370064616203308,
-0.07554586976766586,
0.033385857939720154,
-0.01664753444492817,
-0.028853073716163635,
0.07096148282289505,
-0.018714923411607742,
0.014391876757144928,
0.018524151295423508,
-0.007940943352878094,
0.019049620255827904,
0.03411039337515831,
-0.058784369379282,
0.03765416517853737,
0.0038061724044382572,
-0.014951551333069801,
0.040617309510707855,
0.025838717818260193,
-0.04591548070311546,
0.019325504079461098,
0.001115189166739583,
0.049424104392528534,
-0.05457543581724167,
-0.09818483144044876,
-0.02615053579211235,
0.00757318502292037,
0.03230248764157295,
0.09379833936691284,
-0.05464540794491768,
-0.006116093602031469,
-0.009860904887318611,
-0.061312731355428696,
0.015276322141289711,
-0.06361444294452667,
0.04339996725320816,
0.0613684207201004,
-0.00047101921518333256,
-0.04469727352261543,
0.002678188029676676,
-0.05085179582238197,
-0.05278564989566803,
0.04173891991376877,
0.015878692269325256,
0.02932615950703621,
-0.024465255439281464,
-0.04872870445251465,
0.03601688891649246,
0.07661894708871841,
-0.053732242435216904,
0.05480656772851944,
0.02880588173866272,
0.0425151027739048,
-0.039649929851293564,
-0.05179716646671295,
-0.015428540296852589,
-0.007420770358294249,
0.0032004613894969225,
0.10526684671640396,
-0.07387697696685791,
-0.04674309492111206,
-0.1333160251379013,
0.0045051733031868935,
0.037561479955911636,
0.004195286892354488,
-0.03033549152314663,
0.0220883060246706,
0.017778027802705765,
-0.07671930640935898,
0.0363580659031868,
0.006566325668245554,
0.009092079475522041,
0.03365631401538849,
-0.03557993099093437,
-1.793845154315105e-33,
-0.02884579636156559,
0.06490292400121689,
0.021888645365834236,
0.028564613312482834,
-0.04875937104225159,
0.01440771296620369,
-0.02434917725622654,
-0.04052974656224251,
-0.005242576356977224,
0.03977634012699127,
0.0329405777156353,
0.061938684433698654,
0.0062708184123039246,
-0.031702812761068344,
0.009289794601500034,
0.03827127814292908,
0.022401981055736542,
-0.035733334720134735,
-0.03896588087081909,
-0.0026344298385083675,
0.029914258047938347,
0.0872965157032013,
0.051638707518577576,
-0.012310178950428963,
-0.0858812928199768,
-0.021953027695417404,
0.03066551312804222,
0.01161963026970625,
-0.07967490702867508,
-0.10417864471673965,
0.10255032032728195,
0.02320990525186062,
-0.07935353368520737,
-0.016306262463331223,
0.005852045491337776,
0.024475660175085068,
-0.019093098118901253,
-0.10878367722034454,
0.019715746864676476,
0.14317446947097778,
-0.08667702227830887,
0.049852270632982254,
0.029222402721643448,
-0.003533382900059223,
-0.04879019036889076,
0.0005933760548941791,
0.06606277078390121,
0.025544611737132072,
0.02439226768910885,
-0.03942229598760605,
-0.009869630448520184,
0.04857192188501358,
0.010479915887117386,
-0.01821524277329445,
0.02466447837650776,
-0.037227001041173935,
-0.056616466492414474,
-0.006383384577929974,
-0.06529126316308975,
0.012060417793691158,
0.08407026529312134,
0.03568260744214058,
-0.05201978236436844,
0.05252181366086006,
-0.05555828660726547,
0.06274162232875824,
0.01853153482079506,
-0.1094367578625679,
-0.007233111187815666,
0.0713459774851799,
-0.0055906339548528194,
-0.11549963057041168,
0.036499448120594025,
0.025126546621322632,
-0.024915121495723724,
-0.04332030937075615,
-0.0665980875492096,
0.09540218859910965,
-0.029377920553088188,
0.05228949710726738,
-0.042464256286621094,
0.05651925876736641,
-0.009606841951608658,
-0.07747182995080948,
-0.0262905303388834,
0.06823567301034927,
-0.04559188336133957,
-0.014683025889098644,
0.007741448935121298,
0.05565718561410904,
0.01513691060245037,
0.026494145393371582,
0.011387034319341183,
0.009103749878704548,
-0.0009227038244716823,
-2.2622240081204836e-8,
0.0017286636866629124,
-0.1257413923740387,
-0.036412566900253296,
0.037708353251218796,
-0.03485259786248207,
0.06010360270738602,
-0.10330735892057419,
0.00046759587712585926,
-0.03846268728375435,
-0.0033912796061486006,
0.09889325499534607,
-0.02661939524114132,
-0.10086744278669357,
-0.009111220948398113,
-0.017684701830148697,
-0.08074065297842026,
0.07979173213243484,
-0.002906154841184616,
-0.01925610937178135,
0.052166085690259933,
0.03727056831121445,
-0.04179728403687477,
0.017086084932088852,
-0.019890600815415382,
-0.01481447834521532,
0.04632437601685524,
0.010653582401573658,
0.0019316811813041568,
-0.05117679387331009,
-0.05276620760560036,
0.0626007691025734,
-0.05669690668582916,
0.06529702246189117,
0.018598129972815514,
-0.055736180394887924,
0.041033774614334106,
0.03225328028202057,
0.01690291240811348,
0.0037089036777615547,
0.10098147392272949,
0.06320267170667648,
-0.05352722853422165,
-0.03913462907075882,
0.03652426227927208,
-0.09603153169155121,
0.03968869894742966,
-0.06374779343605042,
-0.0029503884725272655,
-0.0021852694917470217,
-0.07434513419866562,
0.038272012025117874,
-0.1247677281498909,
-0.03518371656537056,
-0.010715988464653492,
-0.010697854682803154,
0.07218504697084427,
-0.049044448882341385,
0.11414632946252823,
0.05525616928935051,
-0.020133892074227333,
0.09295638650655746,
-0.011744475923478603,
-0.0779658704996109,
-0.03394971415400505
] |
PMID:25838188 | Patients were identified from our institutional review board-approved prospective observational protocol. | [
-0.010833332315087318,
-0.023783784359693527,
-0.06781019270420074,
0.0569048672914505,
-0.027981236577033997,
0.010994021780788898,
-0.047254037111997604,
0.04269590601325035,
0.03706583380699158,
-0.04148129001259804,
-0.014797345735132694,
0.02352401614189148,
-0.06500209122896194,
0.09539711475372314,
-0.08004368841648102,
0.02917846292257309,
0.10367567837238312,
-0.049685973674058914,
0.055215995758771896,
0.012183313257992268,
-0.09820351004600525,
0.03558392450213432,
0.038902778178453445,
0.02441268600523472,
-0.024958623573184013,
-0.02025940641760826,
-0.05654682591557503,
-0.0113786980509758,
0.024711426347494125,
0.07393424957990646,
0.023945307359099388,
0.06023222208023071,
-0.005343982484191656,
0.030831122770905495,
0.026058334857225418,
0.020355800166726112,
-0.060921717435121536,
0.014714115299284458,
-0.056979838758707047,
-0.012522620148956776,
0.046556536108255386,
-0.009770373813807964,
0.007788714021444321,
0.05297456309199333,
-0.018326107412576675,
-0.03246912360191345,
-0.01709291897714138,
0.054245270788669586,
-0.006878414656966925,
0.0810648575425148,
-0.026251528412103653,
-0.08938781172037125,
0.07450585067272186,
0.06425601243972778,
-0.05799645930528641,
-0.038884084671735764,
-0.03038119710981846,
-0.08407046645879745,
0.026152655482292175,
0.01489841565489769,
-0.04032568261027336,
-0.008562443777918816,
-0.006796061992645264,
0.05348784849047661,
0.01887943595647812,
0.09462946653366089,
-0.03532801568508148,
-0.11143408715724945,
0.0685335174202919,
-0.019383536651730537,
-0.014402739703655243,
-0.023537777364253998,
0.028511354699730873,
0.049657583236694336,
-0.055835746228694916,
-0.009193186648190022,
0.032225899398326874,
0.007528979331254959,
0.14693613350391388,
-0.0002786728146020323,
-0.04775390401482582,
-0.0006732246256433427,
0.054878994822502136,
-0.02695833146572113,
0.0334702730178833,
-0.039694804698228836,
-0.011440007016062737,
0.03344128653407097,
-0.12059365957975388,
0.005422861780971289,
0.09334190934896469,
0.08394298702478409,
-0.010794884525239468,
-0.0314299501478672,
0.04930807650089264,
0.04617570713162422,
-0.04064241796731949,
-0.04376346990466118,
0.027955999597907066,
0.039947282522916794,
-0.034591637551784515,
0.01569611020386219,
-0.0005186906200833619,
0.036093540489673615,
-0.07406170666217804,
-0.06005684658885002,
-0.034752245992422104,
-0.09613818675279617,
0.056363631039857864,
0.025458160787820816,
0.022413095459342003,
0.03868837282061577,
0.05999784916639328,
-0.0010010626865550876,
-0.0276930071413517,
0.03930474445223808,
0.004123708698898554,
0.060795415192842484,
0.04845121502876282,
-0.004051258321851492,
0.015062353573739529,
-0.03910402953624725,
0.03783509135246277,
-0.11010541021823883,
0.11723048239946365,
0.08546027541160583,
-0.050364140421152115,
-3.244706036315221e-33,
0.047016292810440063,
0.022519370540976524,
0.030204255133867264,
-0.04899786040186882,
0.017476724460721016,
0.07908473163843155,
-0.013996235094964504,
-0.029947828501462936,
-0.00024102185852825642,
-0.035209979861974716,
0.035727161914110184,
0.02499811165034771,
0.11902584135532379,
0.023030387237668037,
-0.10166312754154205,
0.011235281825065613,
-0.034082163125276566,
0.11658390611410141,
-0.08013002574443817,
0.05369929224252701,
-0.0008043118286877871,
0.019454482942819595,
0.0450439415872097,
0.03000185266137123,
-0.03118487261235714,
-0.01901814341545105,
-0.07157700508832932,
0.047224100679159164,
0.03755864500999451,
0.003528015222400427,
-0.007679103408008814,
-0.006328274495899677,
0.007356955669820309,
-0.06620939821004868,
-0.04680218547582626,
0.003108781762421131,
0.04395810514688492,
-0.0006794759538024664,
0.03129998967051506,
-0.04431716352701187,
0.0731368213891983,
0.04274708777666092,
-0.028891272842884064,
0.024689259007573128,
0.022295916453003883,
-0.03460116684436798,
-0.05345805361866951,
-0.04082241281867027,
-0.032155200839042664,
-0.06807348132133484,
-0.012964941561222076,
-0.03714616224169731,
-0.06287319213151932,
-0.06186226010322571,
0.015492812730371952,
0.008215567097067833,
-0.011416698805987835,
0.026304941624403,
0.002083340659737587,
0.0038424860686063766,
0.09800513833761215,
0.12377722561359406,
-0.013609369285404682,
-0.009209640324115753,
-0.05308593809604645,
-0.04503198340535164,
-0.04641902074217796,
-0.025685681030154228,
0.012684816494584084,
-0.02755904197692871,
-0.015470314770936966,
0.050201743841171265,
0.018591655418276787,
0.06766316294670105,
-0.049028389155864716,
-0.07205956429243088,
-0.05584344267845154,
0.026596497744321823,
-0.018472544848918915,
-0.006986298132687807,
0.004320526961237192,
-0.031213000416755676,
-0.04883286729454994,
0.12516601383686066,
0.05696845054626465,
-0.01672239601612091,
-0.05855554714798927,
0.08960314840078354,
-0.055734191089868546,
-0.05517246574163437,
0.048567160964012146,
0.07449138909578323,
0.035481758415699005,
0.08544360846281052,
-0.0069865332916378975,
-5.140651232029392e-34,
-0.0244764257222414,
0.025585724040865898,
0.029055379331111908,
-0.054474323987960815,
0.030380748212337494,
-0.039450857788324356,
-0.014016428962349892,
-0.07727668434381485,
0.14900051057338715,
-0.05730651691555977,
0.05150908604264259,
-0.0034629309084266424,
0.00428248243406415,
-0.029746130108833313,
-0.003275528782978654,
0.07704875618219376,
-0.10314732044935226,
-0.04877113923430443,
-0.039583683013916016,
-0.02372290939092636,
0.04700113832950592,
-0.01056503877043724,
0.03496391326189041,
-0.004434006754308939,
0.020281359553337097,
-0.016434136778116226,
0.17946192622184753,
-0.060337699949741364,
0.025150783360004425,
-0.12392445653676987,
-0.028770335018634796,
0.038187820464372635,
-0.03232481703162193,
-0.022243190556764603,
0.012552700005471706,
0.06887873262166977,
0.055168941617012024,
-0.07626385986804962,
-0.030827436596155167,
-0.035779040306806564,
0.03888038545846939,
0.027563462033867836,
-0.10169876366853714,
0.058649297803640366,
-0.026626866310834885,
-0.00546256871894002,
0.05201737582683563,
0.04724333807826042,
-0.01784197799861431,
-0.03638596087694168,
-0.1012335866689682,
-0.01188522670418024,
-0.019896605983376503,
0.0045236567966639996,
-0.01316042523831129,
-0.05740388110280037,
-0.01552749052643776,
-0.06582529842853546,
-0.053509004414081573,
0.04861192777752876,
0.019526280462741852,
0.019493695348501205,
-0.07189129292964935,
0.05536491423845291,
0.07090508192777634,
0.04977250099182129,
0.04398481547832489,
-0.010897989384829998,
0.014697895385324955,
0.018657824024558067,
-0.0322762168943882,
-0.06419012695550919,
-0.11706792563199997,
0.02659987099468708,
0.05921066179871559,
0.023597268387675285,
0.022564193233847618,
-0.046716585755348206,
-0.014062593691051006,
0.04031636565923691,
-0.0784837156534195,
-0.03937872499227524,
0.03419956937432289,
0.013393869623541832,
0.07826344668865204,
-0.03855296969413757,
0.010256906971335411,
-0.08188749104738235,
0.005481876898556948,
-0.0042542023584246635,
-0.011960290372371674,
-0.07248138636350632,
-0.04476821422576904,
-0.09099887311458588,
-0.0289656613022089,
-2.4654733365991888e-8,
-0.017166413366794586,
-0.045807767659425735,
0.0739608108997345,
-0.02417934313416481,
-0.014565222896635532,
-0.06109018623828888,
-0.05528198555111885,
0.05001990497112274,
-0.05317966267466545,
-0.003907844424247742,
0.014085809700191021,
-0.008749936707317829,
-0.014600572176277637,
-0.07060746103525162,
0.10551019757986069,
-0.05428021773695946,
0.047611769288778305,
0.0917278453707695,
-0.03241155296564102,
-0.016587020829319954,
-0.01919379085302353,
-0.060396306216716766,
0.0677461177110672,
-0.01676785759627819,
-0.0036050451453775167,
0.010031718760728836,
0.03493519499897957,
0.04445447400212288,
-0.06450983881950378,
-0.00025261304108425975,
-0.026925576850771904,
0.017706377431750298,
0.03901732712984085,
-0.036326922476291656,
-0.0033408021554350853,
-0.03626478463411331,
0.027439570054411888,
-0.023097870871424675,
0.10736385732889175,
-0.02513192594051361,
-0.04520709067583084,
-0.05135001987218857,
-0.06081882864236832,
0.04232727736234665,
-0.02390807308256626,
0.03286849334836006,
-0.0007314574322663248,
-0.01655489392578602,
0.03039655275642872,
-0.0778934583067894,
0.06617394834756851,
-0.09204737842082977,
0.06384444981813431,
0.015146052464842796,
-0.0769384428858757,
0.1430722028017044,
0.027904460206627846,
-0.008976236917078495,
0.014494332484900951,
-0.04125802963972092,
0.02635522000491619,
-0.022097347304224968,
-0.05449188873171806,
-0.05592544004321098
] |
PMID:25838188 | A total of 704 metastatic and 1362 primary lesions were obtained from a de-identified metadata pool. | [
0.027118772268295288,
0.025371382012963295,
-0.018241319805383682,
-0.08953879773616791,
0.00607848959043622,
-0.04524562135338783,
-0.0238471832126379,
0.11132722347974777,
0.03135542571544647,
0.08131109923124313,
-0.009003669954836369,
0.0027533734682947397,
-0.0045582749880850315,
0.050774164497852325,
-0.07123232632875443,
0.02259354293346405,
-0.03287046402692795,
-0.07391425967216492,
0.02849608287215233,
0.06658376753330231,
-0.040075331926345825,
0.02984623610973358,
0.013406374491751194,
-0.017280081287026405,
-0.06125595420598984,
0.061501387506723404,
-0.08229274302721024,
0.030833827331662178,
-0.032539431005716324,
-0.0012675455072894692,
0.055079385638237,
0.06237444654107094,
-0.03077651374042034,
-0.008102653548121452,
0.08852754533290863,
-0.042677197605371475,
-0.0510220043361187,
0.07744511216878891,
-0.0003253950271755457,
-0.01172841340303421,
0.041583433747291565,
-0.036102116107940674,
-0.0299372635781765,
-0.005433030426502228,
-0.027498405426740646,
0.002384925028309226,
-0.06686758995056152,
0.008388704620301723,
0.07113072276115417,
0.09647020697593689,
-0.026652073487639427,
0.004548125900328159,
-0.0345943346619606,
0.1908843219280243,
0.03995378315448761,
-0.08755878359079361,
-0.02977115474641323,
-0.045006174594163895,
0.0019996031187474728,
0.07326234132051468,
-0.018126249313354492,
-0.061670076102018356,
0.014522766694426537,
0.03427855670452118,
0.07986433804035187,
0.037190813571214676,
-0.0033947047777473927,
-0.12543882429599762,
0.0561375692486763,
-0.01787000149488449,
0.040071383118629456,
0.08562525361776352,
0.006788258906453848,
0.05675598978996277,
-0.05839507281780243,
0.062261663377285004,
-0.05151920020580292,
0.07320869714021683,
0.0838790014386177,
-0.05858869105577469,
0.04310088977217674,
0.092009536921978,
0.049114715307950974,
-0.025264889001846313,
-0.0189482644200325,
-0.07946856319904327,
0.017537567764520645,
0.013809872791171074,
-0.025942806154489517,
0.018207022920250893,
0.028729815036058426,
0.04154645651578903,
0.030960598960518837,
-0.007493162993341684,
-0.11713577061891556,
0.023219596594572067,
0.018432380631566048,
-0.004270766396075487,
0.05701301619410515,
0.027468577027320862,
0.0034000910818576813,
-0.02735891565680504,
0.02362564578652382,
-0.023821143433451653,
-0.01921653561294079,
-0.03422155603766441,
0.020688289776444435,
-0.034730214625597,
-0.07016360014677048,
-0.02120058238506317,
0.043868206441402435,
0.03606786951422691,
0.04070831462740898,
-0.07688218355178833,
0.07942156493663788,
0.08516954630613327,
-0.011188957840204239,
0.040800340473651886,
0.018197020515799522,
-0.03303420916199684,
-0.008904256857931614,
-0.06591732800006866,
0.01775207743048668,
-0.04155100882053375,
0.0583665668964386,
0.0715886726975441,
-0.12706662714481354,
-2.682768676086304e-33,
0.06922667473554611,
-0.03447912633419037,
0.046362388879060745,
0.01105557382106781,
0.030796805396676064,
-0.007344885729253292,
0.05557478964328766,
-0.017335886135697365,
0.030773421749472618,
-0.0808708518743515,
0.025867708027362823,
0.01527363620698452,
0.06113801524043083,
-0.04958532750606537,
-0.0926070287823677,
0.07266530394554138,
0.028216183185577393,
0.10109533369541168,
-0.06982375681400299,
-0.07742474228143692,
0.03399811312556267,
0.040668047964572906,
0.03369017317891121,
-0.039371002465486526,
-0.04574085772037506,
0.08197468519210815,
-0.07847928255796432,
0.01802741549909115,
0.05757267773151398,
0.026195267215371132,
-0.023223426192998886,
0.006535931024700403,
0.08959852159023285,
0.052698779851198196,
0.00791348796337843,
0.05961203947663307,
0.027018001303076744,
0.00164126162417233,
0.08229852467775345,
0.04272287338972092,
0.06990312039852142,
0.014510436914861202,
0.019366387277841568,
-0.02079470455646515,
-0.06335339695215225,
-0.05736541002988815,
-0.028236394748091698,
-0.051461175084114075,
-0.011651680804789066,
0.010071494616568089,
0.0298429224640131,
0.007928416132926941,
-0.06406182050704956,
-0.026552539318799973,
-0.054330892860889435,
0.023155804723501205,
-0.0634428933262825,
-0.03929127752780914,
0.00968489795923233,
0.0318903848528862,
0.08545276522636414,
0.019093843176960945,
-0.05114128813147545,
0.0910758525133133,
-0.010163742117583752,
-0.05625953525304794,
0.022920094430446625,
-0.02835739403963089,
-0.014508340507745743,
0.02285458892583847,
-0.04570832476019859,
0.017268452793359756,
0.08385417610406876,
-0.06662605702877045,
-0.022400684654712677,
-0.016797997057437897,
0.05217638239264488,
-0.048356860876083374,
-0.1102379560470581,
0.1380130499601364,
-0.1387728452682495,
0.02374635636806488,
-0.07835322618484497,
0.04638735577464104,
-0.07255715131759644,
-0.012798754498362541,
-0.013439160771667957,
-0.02694876305758953,
-0.038648948073387146,
-0.005282151512801647,
0.020714091137051582,
-0.0034629888832569122,
-0.10453570634126663,
-0.0035190193448215723,
-0.03304322436451912,
4.5137968289343295e-34,
-0.0178684089332819,
-0.02283303253352642,
0.04628705978393555,
-0.0063621411100029945,
-0.04749660566449165,
0.05384214594960213,
0.046098459511995316,
0.05758489668369293,
-0.03912080079317093,
-0.0035242438316345215,
0.019783753901720047,
0.07107401639223099,
-0.07230901718139648,
-0.07645397633314133,
-0.049077823758125305,
0.038825973868370056,
-0.025480695068836212,
-0.02508655935525894,
-0.007924200035631657,
0.020990988239645958,
0.021668685600161552,
0.05867861583828926,
0.01087422575801611,
0.06873675435781479,
0.002980948192998767,
0.002484360244125128,
0.02996068075299263,
-0.07091988623142242,
0.005929924547672272,
-0.0070724450051784515,
0.03787877783179283,
0.07504269480705261,
-0.04038269445300102,
-0.05710778385400772,
-0.0074166543781757355,
-0.04564386233687401,
0.008639747276902199,
-0.16404233872890472,
0.017240669578313828,
-0.006860552355647087,
-0.0231173112988472,
-0.007775734178721905,
0.01243817713111639,
0.017458627000451088,
-0.006464352831244469,
-0.05803080275654793,
0.009984138421714306,
0.08372359722852707,
0.12050451338291168,
-0.01003824919462204,
-0.03440309315919876,
-0.005849728360772133,
-0.08180767297744751,
-0.04573553800582886,
-0.010116408579051495,
-0.03866324573755264,
-0.02986987493932247,
0.030308032408356667,
-0.08162928372621536,
0.053885698318481445,
0.01226012222468853,
0.0004740944132208824,
-0.12721417844295502,
-0.03368126228451729,
0.038257308304309845,
0.08897485584020615,
0.021024566143751144,
-0.05023321509361267,
-0.06828238815069199,
0.02954741008579731,
-0.01228364184498787,
0.005865465849637985,
-0.07223536819219589,
-0.027161044999957085,
0.025694629177451134,
0.03716742992401123,
0.0031779452692717314,
-0.030112598091363907,
-0.030537666752934456,
0.07015416026115417,
0.013268373906612396,
0.030729683116078377,
0.029997674748301506,
-0.015620983205735683,
0.05426948890089989,
0.05143202468752861,
-0.04763464629650116,
0.006299906875938177,
-0.10958272963762283,
-0.01262968871742487,
0.002482121344655752,
-0.063689686357975,
-0.05765041708946228,
-0.0005666062934324145,
-0.037381842732429504,
-2.7788038536868953e-8,
-0.04298149049282074,
-0.005289473570883274,
0.013178627006709576,
-0.048434577882289886,
0.0035553190391510725,
-0.009854696691036224,
-0.06981468200683594,
0.09333965182304382,
0.059125613421201706,
-0.043463435024023056,
0.03941834717988968,
-0.0449833907186985,
-0.05125729739665985,
-0.04926948994398117,
-0.018958665430545807,
-0.03350866585969925,
0.01408936083316803,
-0.0038929302245378494,
-0.030820336192846298,
-0.009622721001505852,
-0.0171666257083416,
-0.0300592090934515,
0.06356872618198395,
-0.10510817170143127,
0.045199375599622726,
0.009819701313972473,
0.02551010064780712,
-0.00025453855050727725,
-0.04133611172437668,
-0.022145742550492287,
0.05308936536312103,
-0.06489692628383636,
-0.0167424064129591,
-0.02419767715036869,
0.08143630623817444,
0.005252429284155369,
0.03438355401158333,
-0.033217210322618484,
-0.056533996015787125,
0.03480001911520958,
0.06631740182638168,
0.03782963380217552,
-0.012504671700298786,
-0.00846821628510952,
-0.10778940469026566,
0.042488422244787216,
-0.07728298753499985,
0.07257886230945587,
0.005940793547779322,
-0.06757258623838425,
0.0057565257884562016,
-0.0639781653881073,
-0.02143343910574913,
0.035995785146951675,
-0.04714890196919441,
0.06908906251192093,
0.013655767776072025,
0.06189868226647377,
0.05449705570936203,
-0.0029069967567920685,
0.11483202129602432,
-0.01733297109603882,
-0.02459125593304634,
0.006310093216598034
] |
PMID:25838188 | RSI was calculated using the previously published rank-based algorithm. | [
-0.052091408520936966,
0.004959451965987682,
-0.06706108897924423,
0.00865436252206564,
-0.0015955272829160094,
0.02102157287299633,
-0.08240679651498795,
0.04606030508875847,
-0.024828776717185974,
0.007098522502928972,
-0.03224768862128258,
0.11855150759220123,
0.10257106274366379,
0.016689177602529526,
-0.06554567813873291,
-0.07645653933286667,
-0.046433862298727036,
-0.009308489970862865,
-0.012980333529412746,
-0.0789756178855896,
0.01268403884023428,
0.013840309344232082,
0.012242005206644535,
-0.07806546241044998,
0.12146060913801193,
-0.051979370415210724,
-0.011591111309826374,
0.008788729086518288,
0.032913751900196075,
0.032591141760349274,
0.06323552131652832,
0.06483862549066544,
0.09674705564975739,
-0.03335421904921532,
-0.13107356429100037,
-0.028601769357919693,
0.005873729474842548,
-0.03926624730229378,
0.08646375685930252,
0.022042548283934593,
0.03564434126019478,
-0.020167266950011253,
-0.039769843220710754,
-0.06036324054002762,
0.07584841549396515,
0.00018322242249269038,
-0.09325435012578964,
0.03241109475493431,
-0.0334974005818367,
0.009421068243682384,
-0.08027993887662888,
0.046992722898721695,
0.008506656624376774,
0.10143174976110458,
0.014766630716621876,
-0.08489813655614853,
0.0006318265222944319,
-0.06751297414302826,
-0.016783718019723892,
-0.03912540525197983,
0.013708261772990227,
0.006767323240637779,
-0.006499873008579016,
-0.02570003643631935,
0.05959341675043106,
0.06749329715967178,
0.005379440262913704,
-0.10922226309776306,
0.04604088142514229,
-0.041231490671634674,
-0.07508648931980133,
0.014375394210219383,
-0.013453136198222637,
0.008484245277941227,
-0.04680915176868439,
-0.012206247076392174,
-0.018021421507000923,
0.03651265799999237,
-0.035229407250881195,
-0.05437624827027321,
0.016794422641396523,
-0.012138844467699528,
-0.05173569917678833,
0.046883199363946915,
0.09464500844478607,
0.04605729132890701,
0.03515734151005745,
-0.006544467993080616,
0.005864616949111223,
0.03499366715550423,
0.07719658315181732,
-0.012825066223740578,
-0.020849619060754776,
-0.0014313914580270648,
0.013691075146198273,
-0.04241267219185829,
-0.07348859310150146,
0.03322264179587364,
0.07695797085762024,
-0.004658267833292484,
-0.04459554702043533,
0.023571578785777092,
-0.09617730975151062,
-0.052097197622060776,
0.019759517163038254,
0.003922454547137022,
0.03282942622900009,
0.023783141747117043,
0.03853268548846245,
-0.05246283486485481,
-0.0168203953653574,
0.03283092752099037,
-0.035311926156282425,
0.020123980939388275,
-0.032607439905405045,
0.07431773096323013,
-0.009156872518360615,
0.12214876711368561,
0.06300897896289825,
0.035948123782873154,
0.04654259234666824,
0.03054089844226837,
0.024754242971539497,
0.018168995156884193,
-0.014362134039402008,
0.0765613317489624,
-0.04307766631245613,
-1.3704213443958664e-33,
0.012655720114707947,
0.07183293253183365,
0.03493737801909447,
-0.004348605405539274,
-0.02937752939760685,
-0.008735960349440575,
-0.09041260927915573,
-0.01870286650955677,
0.04820922762155533,
-0.02028338424861431,
-0.015368021093308926,
0.09316515177488327,
0.03550230711698532,
-0.024726107716560364,
0.02329133078455925,
-0.019097497686743736,
-0.01074107363820076,
0.07697760313749313,
-0.0033183300402015448,
-0.004523113369941711,
0.09706269204616547,
-0.021382715553045273,
0.04848887026309967,
-0.08522284775972366,
0.05073639750480652,
0.039993707090616226,
-0.006181460805237293,
-0.027465829625725746,
0.02089388109743595,
0.009341753087937832,
0.0769025981426239,
-0.01246414240449667,
-0.09863267838954926,
-0.04104885086417198,
0.017391962930560112,
0.00347713939845562,
0.06387320905923843,
-0.03614730387926102,
0.014325639232993126,
0.023693012073636055,
-0.009703783318400383,
0.07613494992256165,
-0.0049222116358578205,
-0.02236870490014553,
-0.12041401118040085,
-0.0005059668910689652,
-0.0951252281665802,
0.01581605337560177,
0.07744785398244858,
0.04387979954481125,
-0.06925269216299057,
-0.03561188280582428,
0.022087255492806435,
-0.04790986329317093,
-0.012134508229792118,
-0.06344620883464813,
0.025082439184188843,
0.03319401293992996,
0.017038874328136444,
0.06621798872947693,
0.036965176463127136,
0.005854624789208174,
0.002899178070947528,
0.0026274798437952995,
0.016696255654096603,
0.04794643819332123,
0.029533352702856064,
-0.0985766351222992,
0.04343147948384285,
0.07781705260276794,
0.01931823417544365,
0.06829818338155746,
0.015260337851941586,
0.00112403545062989,
-0.0269006360322237,
-0.0878608301281929,
-0.0010977924102917314,
0.054269686341285706,
0.03902572765946388,
-0.03654034435749054,
-0.04870522394776344,
0.10198596119880676,
-0.014561756514012814,
-0.037737488746643066,
0.07220064103603363,
-0.03494943305850029,
-0.04776042327284813,
0.0307981688529253,
-0.08795356750488281,
-0.08719706535339355,
0.0474947988986969,
-0.013512757606804371,
0.0277700275182724,
0.034800246357917786,
-0.044655151665210724,
1.1430001972167055e-33,
-0.117896169424057,
0.018276844173669815,
0.032089076936244965,
0.012119500897824764,
-0.06583475321531296,
-0.06753609329462051,
-0.06563034653663635,
0.0024720770306885242,
0.028341898694634438,
0.05991225689649582,
0.06798167526721954,
-0.04868745431303978,
0.025271417573094368,
0.06029125675559044,
0.12251149117946625,
0.02882540225982666,
-0.07480587810277939,
-0.05573407933115959,
-0.03620719537138939,
0.04290276765823364,
0.06458240002393723,
0.023665694519877434,
-0.006352355238050222,
0.02317938394844532,
0.06329654157161713,
0.04420214891433716,
0.09010639786720276,
0.01777730882167816,
-0.05645528808236122,
-0.15451675653457642,
-0.00033198052551597357,
-0.08114621043205261,
-0.13784357905387878,
0.008397839963436127,
-0.0646902322769165,
0.06885398924350739,
-0.008318901993334293,
-0.0619790144264698,
0.03979170322418213,
0.0297883041203022,
-0.008852587081491947,
0.08653251826763153,
-0.05874152481555939,
-0.018427779898047447,
0.007661101873964071,
-0.010132734663784504,
-0.017047952860593796,
0.05518663674592972,
0.04576583206653595,
-0.06081047281622887,
0.020162325352430344,
-0.006059511099010706,
0.016892705112695694,
-0.019244588911533356,
0.023684244602918625,
0.03418934717774391,
-0.04924067109823227,
0.08259492367506027,
0.00527025293558836,
-0.07642102241516113,
0.06740320473909378,
-0.01330337580293417,
0.03257344290614128,
0.0553901307284832,
-0.10726800560951233,
0.01018009427934885,
0.08616555482149124,
-0.06925461441278458,
-0.02996908500790596,
-0.025590302422642708,
0.05263064429163933,
0.003727938747033477,
0.04026428982615471,
0.040962960571050644,
-0.06420938670635223,
0.001725610694848001,
-0.039141952991485596,
0.04172329977154732,
-0.021981792524456978,
-0.02199717052280903,
-0.04269309341907501,
0.04099461808800697,
-0.03972356766462326,
-0.05118994042277336,
0.003776844358071685,
0.02524488791823387,
0.09780865162611008,
-0.06262140721082687,
0.05001045763492584,
-0.023751800879836082,
-0.021720683202147484,
0.011262594722211361,
0.007261189166456461,
0.031183751299977303,
-0.026317048817873,
-1.681707040290803e-8,
0.03683614358305931,
-0.07124902307987213,
-0.09641133248806,
0.061588700860738754,
0.06056899204850197,
0.03478887304663658,
-0.02117101289331913,
-0.024309955537319183,
-0.07724657654762268,
-0.06716717034578323,
0.07821306586265564,
-0.10159879177808762,
-0.008975492790341377,
-0.036821555346250534,
0.03804761543869972,
-0.04797384515404701,
0.011287025175988674,
0.01068662665784359,
-0.002429886953905225,
-0.008696715347468853,
0.11084891110658646,
0.057095691561698914,
0.050628677010536194,
-0.0016290353378280997,
-0.0011083356803283095,
0.04050181806087494,
0.009367412887513638,
-0.03619104623794556,
0.01184458564966917,
-0.05460730940103531,
0.05040862038731575,
-0.01487412117421627,
0.04900292679667473,
0.008530981838703156,
0.008162443526089191,
0.06999140977859497,
0.019474990665912628,
0.05582582578063011,
-0.01889721117913723,
0.0346783846616745,
-0.0038603991270065308,
-0.07105673104524612,
-0.04112842679023743,
0.03641178831458092,
0.08666938543319702,
0.07249508053064346,
-0.04976161569356918,
0.0028863565530627966,
0.017766054719686508,
-0.07907973229885101,
0.0687985047698021,
-0.08828885108232498,
-0.011564143933355808,
-0.0197231937199831,
-0.03073931485414505,
0.020822137594223022,
-0.04632875695824623,
-0.01919565163552761,
0.04137212783098221,
-0.05169982463121414,
0.06293246150016785,
-0.02404494769871235,
-0.08922268450260162,
0.03259202092885971
] |
PMID:25838188 | An independent cohort of 29 lung or liver colon metastases treated with 60 Gy in 5 fractions stereotactic body radiation therapy (SBRT) was used for validation. | [
0.11939521878957748,
-0.043280020356178284,
-0.029567379504442215,
-0.054425518959760666,
-0.023273421451449394,
-0.04588276892900467,
-0.03057163767516613,
0.1035066619515419,
-0.009054786525666714,
0.02769141085445881,
-0.022184904664754868,
0.026367664337158203,
0.0035141240805387497,
0.045295294374227524,
-0.016566816717386246,
0.0229930579662323,
0.06348488479852676,
-0.049362022429704666,
-0.0001962870010174811,
-0.018739966675639153,
-0.10413496196269989,
0.015358646400272846,
0.02820557914674282,
0.004895362537354231,
0.021983208134770393,
-0.051351577043533325,
-0.025366617366671562,
-0.026678916066884995,
-0.030555114150047302,
0.021461250260472298,
0.05642620101571083,
0.008030337281525135,
0.01966770924627781,
-0.023621711879968643,
-0.026919618248939514,
-0.04629160836338997,
0.0008785513928160071,
0.09816041588783264,
-0.09762119501829147,
0.0366801917552948,
-0.07023447751998901,
-0.033459216356277466,
-0.04249676316976547,
0.050116878002882004,
0.01697889156639576,
-0.0612020380795002,
-0.15564298629760742,
-0.05370795354247093,
0.058463986963033676,
0.09525150805711746,
-0.010708078742027283,
0.01538276206701994,
-0.12727391719818115,
0.15329399704933167,
0.05583742633461952,
-0.08473847061395645,
-0.0493367575109005,
-0.0487082377076149,
0.06848892569541931,
-0.04107978940010071,
-0.030448146164417267,
-0.05797994136810303,
0.01398519892245531,
0.008686083368957043,
0.10060657560825348,
0.019316919147968292,
0.0005695878644473851,
-0.06974124163389206,
-0.013760671950876713,
0.015819670632481575,
0.014973157085478306,
0.014728710055351257,
-0.027766186743974686,
0.0031449212692677975,
-0.13272446393966675,
0.016106178984045982,
-0.013331019319593906,
0.011490494944155216,
0.0342879518866539,
0.09126515686511993,
0.016155198216438293,
0.03149285539984703,
-0.012138106860220432,
-0.008899848908185959,
-0.053455792367458344,
0.0053808558732271194,
-0.07922651618719101,
0.09014531224966049,
-0.04226222261786461,
-0.01515637245029211,
0.02774105593562126,
0.004337766207754612,
0.049251776188611984,
-0.029623031616210938,
-0.030845385044813156,
0.015091326087713242,
-0.08522408455610275,
-0.04922445863485336,
0.050905581563711166,
0.021147379651665688,
-0.028325477614998817,
-0.07115282863378525,
-0.04711020365357399,
0.02684398926794529,
-0.03320668265223503,
-0.02533654123544693,
0.015194408595561981,
0.039696164429187775,
-0.04631173238158226,
-0.013951065950095654,
0.05653395876288414,
0.03349879011511803,
-0.023396868258714676,
0.040693096816539764,
0.009483098983764648,
0.17845594882965088,
0.043580006808042526,
0.03643350675702095,
0.04196697473526001,
-0.02629050612449646,
-0.007034404668956995,
0.043783579021692276,
0.06805586069822311,
-0.062160830944776535,
-0.00043970454134978354,
-0.040579963475465775,
0.05859106034040451,
9.868099669355442e-34,
0.0408446341753006,
0.04454036429524422,
0.03310035914182663,
0.0017301139887422323,
0.037042099982500076,
-0.03947706148028374,
0.03750596195459366,
-0.05761575698852539,
0.006352225784212351,
-0.029509710147976875,
0.040464919060468674,
-0.004515238106250763,
0.08778219670057297,
-0.06516792625188828,
-0.06107617914676666,
0.022879263386130333,
-0.06457551568746567,
0.08111783117055893,
-0.12326118350028992,
-0.0687093511223793,
0.02748095616698265,
0.008512510918080807,
0.019288834184408188,
0.004062343388795853,
0.04577196016907692,
0.031594131141901016,
-0.03782564029097557,
0.07271040976047516,
0.0027199448086321354,
0.0101526640355587,
-0.01396235916763544,
0.0270774457603693,
0.10605465620756149,
0.09375856816768646,
-0.04831529036164284,
-0.0033596784342080355,
-0.027118364349007607,
-0.026063479483127594,
0.04538129270076752,
0.03155876696109772,
0.0903971791267395,
0.0101692583411932,
-0.01824812777340412,
-0.00018847921455744654,
0.0432317890226841,
-0.0964764654636383,
-0.06329748034477234,
0.011597500182688236,
-0.0722169354557991,
0.07326041162014008,
0.01919458620250225,
-0.005385950207710266,
-0.06059052050113678,
-0.018152600154280663,
0.07930666953325272,
-0.021070219576358795,
-0.04760212451219559,
0.08177243918180466,
0.0005563225713558495,
0.00903766043484211,
0.10499901324510574,
-0.042815402150154114,
0.015415453352034092,
0.05899801105260849,
-0.009899046272039413,
0.04268303140997887,
-0.0696997120976448,
-0.02608904242515564,
-0.06770258396863937,
0.058441367000341415,
-0.06388027220964432,
0.033939462155103683,
-0.04427863657474518,
0.0531078465282917,
-0.0027679684571921825,
-0.08961229771375656,
0.08431538194417953,
0.006306211464107037,
-0.10041092336177826,
0.06686766445636749,
-0.010703799314796925,
-0.020881637930870056,
-0.11885371804237366,
0.08944840729236603,
0.012107633985579014,
-0.023698167875409126,
-0.03689751401543617,
-0.01578490063548088,
-0.024357115849852562,
-0.03275412693619728,
0.003481064224615693,
-0.026908649131655693,
-0.06261678785085678,
0.06043991446495056,
0.0028741045389324427,
-2.8030441560364865e-33,
-0.026957450434565544,
0.010629391297698021,
0.047082334756851196,
0.03200894966721535,
0.0014019787777215242,
0.02568919025361538,
0.06398598849773407,
-0.05272829532623291,
0.0018335438799113035,
-0.008654984645545483,
-0.024767562747001648,
0.10232000052928925,
-0.031338367611169815,
-0.05450591817498207,
-0.07405560463666916,
0.01350014191120863,
0.06312340497970581,
-0.11066202074289322,
-0.044384196400642395,
0.006681077182292938,
0.019259797409176826,
0.044468943029642105,
0.05018480122089386,
-0.022970838472247124,
-0.09375609457492828,
-0.022039217874407768,
0.051323071122169495,
-0.051936645060777664,
0.055180568248033524,
0.020456690341234207,
0.004517022520303726,
0.06369974464178085,
-0.05961601436138153,
0.009336431510746479,
0.06795904785394669,
0.03464159741997719,
0.03679022565484047,
0.016469009220600128,
0.0028685536235570908,
-0.017420057207345963,
-0.07855083048343658,
0.005108958575874567,
0.0041632927022874355,
-0.013706552796065807,
-0.0579061396420002,
0.026415321975946426,
0.08643977344036102,
-0.05093666911125183,
0.03458641842007637,
-0.0769999548792839,
-0.04814566671848297,
-0.0000764529177104123,
-0.03236275911331177,
0.05628743767738342,
-0.045983996242284775,
-0.07906846702098846,
-0.09524845331907272,
-0.0259768757969141,
-0.042304933071136475,
-0.016718531027436256,
0.020166808739304543,
0.03751891106367111,
0.010562051087617874,
-0.05873643979430199,
0.029232991859316826,
0.1250912845134735,
-0.03404730185866356,
-0.03359517082571983,
-0.06226796656847,
0.04428442567586899,
0.006604719441384077,
-0.08549836277961731,
-0.0689130499958992,
0.07878725230693817,
-0.018117373809218407,
0.018690790981054306,
0.05724121257662773,
-0.00447925366461277,
-0.004882614128291607,
0.04002907872200012,
-0.024764621630311012,
0.09997832030057907,
-0.005495936144143343,
-0.02224620059132576,
0.05414853245019913,
0.031085297465324402,
-0.06730005890130997,
0.07859030365943909,
-0.03421318531036377,
0.04855835810303688,
-0.007008259184658527,
-0.0013390653766691685,
-0.008397441357374191,
-0.00616676639765501,
0.035233158618211746,
-3.098949719060329e-8,
-0.05870456621050835,
-0.027811968699097633,
0.005519856698811054,
0.0410798154771328,
-0.09305458515882492,
0.03798890858888626,
-0.023640936240553856,
-0.03012952022254467,
0.007388508878648281,
-0.016729379072785378,
-0.00046585965901613235,
0.0676068663597107,
-0.021336542442440987,
0.018919218331575394,
-0.05515862628817558,
-0.009009390138089657,
-0.01957741007208824,
0.02869543805718422,
0.008247269317507744,
-0.00942984875291586,
-0.04799884930253029,
-0.06009572744369507,
0.12591679394245148,
-0.0735614150762558,
-0.041122566908597946,
0.06410608440637589,
0.01275514718145132,
0.06201225891709328,
-0.01589176245033741,
-0.001985339680686593,
0.038190122693777084,
-0.01677515357732773,
-0.03924524039030075,
-0.019997768104076385,
-0.04403151199221611,
-0.013838698156177998,
0.0335838720202446,
-0.0024508177302777767,
0.0340610034763813,
0.061294108629226685,
0.05390071123838425,
0.03335569053888321,
0.0031016648281365633,
0.0013512192526832223,
-0.07908634096384048,
0.041701849550008774,
-0.09520315378904343,
0.012124398723244667,
-0.0488041453063488,
0.01079674530774355,
0.06396891176700592,
-0.11614162474870682,
-0.01878025382757187,
-0.03885321319103241,
-0.032538820058107376,
0.09271834790706635,
0.06783464550971985,
-0.05267542973160744,
0.013377835974097252,
-0.011452984064817429,
0.012596560642123222,
0.002489598235115409,
-0.0076535786502063274,
-0.04916701093316078
] |
PMID:25838188 | The most common sites of metastases included liver (n=374; 53%), lung (n=116; 17%), and lymph nodes (n=40; 6%). | [
0.10419661551713943,
-0.010088290087878704,
-0.05118777975440025,
-0.0670555830001831,
0.022842325270175934,
-0.03754117339849472,
-0.05854685604572296,
0.09098578244447708,
-0.030188284814357758,
0.02819794975221157,
-0.0310287494212389,
-0.007127012591809034,
-0.005420605186372995,
0.019573688507080078,
-0.0013286068569868803,
-0.009902605786919594,
-0.03486606478691101,
-0.09062404930591583,
0.009799206629395485,
-0.01814611442387104,
-0.043477144092321396,
-0.02012590318918228,
0.06177578121423721,
-0.05652270466089249,
0.08619708567857742,
-0.10888419300317764,
-0.03490372747182846,
0.042356930673122406,
-0.0025690505281090736,
-0.029583102092146873,
-0.024446804076433182,
-0.04071447625756264,
-0.04818869009613991,
-0.05044149234890938,
-0.003936300054192543,
-0.050413839519023895,
-0.017097944393754005,
0.10772004723548889,
-0.027638625353574753,
0.050622906535863876,
-0.0028895416762679815,
-0.0005650185630656779,
-0.007748119067400694,
-0.011760697700083256,
0.05638973042368889,
0.0034897339064627886,
-0.1266009360551834,
0.017077242955565453,
0.02103443630039692,
0.1173178181052208,
-0.039231836795806885,
-0.009876568801701069,
-0.05336900055408478,
0.19325527548789978,
-0.007569200359284878,
-0.034734513610601425,
-0.04355023428797722,
-0.07390082627534866,
0.05731695145368576,
-0.06903117895126343,
-0.025348074734210968,
-0.013270898722112179,
0.016848741099238396,
-0.005321746226400137,
0.0932556539773941,
0.03495998680591583,
0.014029717072844505,
-0.08866522461175919,
-0.056807100772857666,
0.021788284182548523,
0.0998346209526062,
0.006667010486125946,
-0.009840651415288448,
-0.01236100122332573,
-0.07537833601236343,
0.08025053888559341,
-0.02742087095975876,
0.015242485329508781,
0.014863085933029652,
0.028010884299874306,
-0.04414861649274826,
0.07744394242763519,
0.010773759335279465,
0.01566368341445923,
-0.08640497177839279,
-0.036024678498506546,
-0.0739070400595665,
0.04351659491658211,
-0.06375493854284286,
0.015832839533686638,
-0.04737873375415802,
0.03335917368531227,
-0.008433104492723942,
-0.0158136785030365,
0.018984707072377205,
0.07925266772508621,
0.018362082540988922,
0.007151813246309757,
0.0634288564324379,
-0.04488338157534599,
0.008064625784754753,
-0.025512749329209328,
0.05802793800830841,
-0.04341176524758339,
-0.0555083341896534,
0.042264338582754135,
-0.02013770118355751,
0.0791143923997879,
-0.07657789438962936,
-0.012475547380745411,
0.014357452280819416,
0.02622625231742859,
0.013874285854399204,
-0.01791883260011673,
0.10796060413122177,
0.047672443091869354,
0.04222683981060982,
-0.028355160728096962,
0.015352643094956875,
0.04806339368224144,
-0.05146923288702965,
-0.005185414105653763,
0.04460002854466438,
0.011011956259608269,
0.04492253437638283,
0.015163795091211796,
-0.05981895327568054,
-9.917887365242535e-34,
0.15081177651882172,
-0.022656815126538277,
0.026894643902778625,
0.03803456202149391,
0.015871405601501465,
0.03863810375332832,
0.02095011994242668,
-0.005877749528735876,
0.007371074054390192,
-0.0504995696246624,
0.013014731928706169,
0.03010096773505211,
0.05706746503710747,
-0.06353293359279633,
-0.07083942741155624,
0.01862560212612152,
0.04170403257012367,
-0.003155873855575919,
-0.10215659439563751,
-0.12983153760433197,
0.004986176732927561,
0.011361091397702694,
-0.034037597477436066,
-0.005475917365401983,
-0.004564957693219185,
0.056573543697595596,
-0.06723615527153015,
0.04630638659000397,
-0.04323868453502655,
-0.0002567764313425869,
-0.0028408674988895655,
-0.015337885357439518,
0.07445774227380753,
0.06863623857498169,
-0.00005996523759677075,
0.05698799341917038,
-0.02814018912613392,
0.06037253141403198,
-0.03028077818453312,
0.05422596633434296,
0.05946224927902222,
-0.020851315930485725,
0.017360135912895203,
-0.05060767009854317,
-0.02072337456047535,
-0.11250148713588715,
-0.14634506404399872,
-0.03093907982110977,
-0.006944590713828802,
0.04013001173734665,
0.003722163150086999,
-0.0020664536859840155,
-0.008975840173661709,
-0.00761078204959631,
0.03859266638755798,
-0.007581423502415419,
-0.09726178646087646,
-0.020320311188697815,
-0.0433255210518837,
0.09756460785865784,
0.10071532428264618,
-0.03364524617791176,
-0.001021146192215383,
0.10230989009141922,
-0.07415598630905151,
-0.010245678946375847,
-0.05890464782714844,
-0.05793403834104538,
-0.08293968439102173,
0.08778639137744904,
-0.049152567982673645,
-0.003631442319601774,
0.06546328961849213,
-0.030817236751317978,
-0.03903507813811302,
0.010688289999961853,
0.05215909704566002,
-0.05008240416646004,
-0.09749827533960342,
0.10041221231222153,
-0.014809923246502876,
0.005801719147711992,
-0.1524686962366104,
0.018974849954247475,
0.02377183735370636,
-0.07351376116275787,
-0.002454053144901991,
-0.11090616136789322,
-0.03231606259942055,
-0.007678458467125893,
0.03946071118116379,
-0.06757231056690216,
-0.033134132623672485,
0.02352401614189148,
-0.038033999502658844,
-2.8621224817278992e-33,
-0.01806716062128544,
-0.007383332587778568,
0.10015814751386642,
0.0012121174950152636,
-0.0024739631917327642,
0.05447055771946907,
0.055563244968652725,
-0.050969067960977554,
-0.012929078191518784,
0.03935077786445618,
-0.03308761492371559,
0.0792352706193924,
-0.03439319133758545,
-0.035341549664735794,
-0.04778926447033882,
-0.04031214863061905,
0.09517072141170502,
0.0042865886352956295,
0.059435442090034485,
0.03250656649470329,
-0.030613383278250694,
-0.00829627551138401,
-0.007915420457720757,
0.02898518554866314,
-0.020432190969586372,
-0.010652583092451096,
-0.08509272336959839,
-0.05887974798679352,
-0.01708175055682659,
-0.011121532879769802,
-0.04194610193371773,
0.06231880187988281,
0.004468648694455624,
0.002008545445278287,
-0.028959615156054497,
0.042179375886917114,
-0.03542158380150795,
-0.042147740721702576,
0.106195367872715,
-0.02146182395517826,
0.030057217925786972,
-0.07002086937427521,
0.018734293058514595,
0.057287201285362244,
0.013817567378282547,
0.04167775437235832,
0.041984353214502335,
-0.004698354750871658,
0.08521148562431335,
-0.027711978182196617,
-0.017946669831871986,
-0.015890859067440033,
-0.03964165225625038,
0.0452069453895092,
0.018147895112633705,
0.06871911138296127,
-0.10011856257915497,
0.08260843902826309,
0.026811018586158752,
-0.00705207884311676,
0.03984934464097023,
-0.010825910605490208,
-0.07542851567268372,
-0.01028190366923809,
0.001978906337171793,
0.05394461750984192,
0.005463865585625172,
-0.05550932511687279,
-0.04834860563278198,
0.0852002426981926,
-0.011543787084519863,
-0.028861811384558678,
-0.04155738651752472,
0.04141956940293312,
0.0038932824973016977,
0.012374029494822025,
0.04205610230565071,
0.005145787727087736,
-0.02249917760491371,
0.00353214330971241,
0.03152598813176155,
0.04602281004190445,
0.01956166699528694,
-0.10145153850317001,
0.05285663157701492,
0.005540067795664072,
-0.04689023271203041,
0.028257865458726883,
-0.043584588915109634,
-0.021422909572720528,
-0.026187174022197723,
-0.004089372232556343,
-0.07346440851688385,
-0.06940661370754242,
-0.02566784992814064,
-3.828752426215942e-8,
-0.014899990521371365,
0.0199808981269598,
0.0046131364069879055,
-0.0034333199728280306,
-0.04933132603764534,
0.03654932603240013,
0.059113889932632446,
0.04854694381356239,
0.03164691478013992,
0.02637624181807041,
0.03697852045297623,
0.044729623943567276,
-0.04161148890852928,
-0.0837453082203865,
0.030355606228113174,
0.003580232849344611,
-0.056329283863306046,
0.012957144528627396,
0.017221184447407722,
-0.014471418224275112,
-0.05768616870045662,
-0.022233925759792328,
0.026620859280228615,
-0.019294969737529755,
-0.014596223831176758,
0.022724254056811333,
0.03108922950923443,
0.07164903730154037,
-0.02441592514514923,
0.029703345149755478,
0.023353878408670425,
-0.09126957505941391,
0.057268962264060974,
-0.08696244657039642,
0.027312148362398148,
0.04092712327837944,
0.02402014471590519,
-0.008854061365127563,
-0.039509594440460205,
-0.00947826448827982,
0.06661361455917358,
-0.024720720946788788,
0.0007693391526117921,
-0.02937903441488743,
-0.035480085760354996,
0.010116120800375938,
-0.06626661866903305,
0.0931495800614357,
0.011566771194338799,
-0.06834091991186142,
-0.03299299255013466,
-0.15640874207019806,
-0.02030583657324314,
-0.06639733910560608,
-0.023363860324025154,
0.09246847033500671,
0.05542093515396118,
-0.004773923195898533,
0.0592721663415432,
0.017041580751538277,
0.03452916443347931,
0.10607077181339264,
0.00402818201109767,
-0.028491854667663574
] |
PMID:25838188 | Sixty percent of metastatic tumors, compared with 54% of primaries, were in the RSI radiation-resistant peak, suggesting metastatic tumors may be slightly more radiation resistant than primaries (P=.01). | [
0.08723214268684387,
0.02353484556078911,
-0.04620670899748802,
-0.01448634173721075,
0.045784998685121536,
-0.007059755735099316,
-0.00231785885989666,
0.1344834864139557,
-0.0039372071623802185,
0.02243741601705551,
-0.04643956199288368,
0.026367560029029846,
0.08254119753837585,
0.04657580703496933,
0.023923194035887718,
0.003699541324749589,
0.027184808626770973,
-0.06470980495214462,
-0.004238405264914036,
0.0828351080417633,
-0.12866036593914032,
-0.04247404634952545,
0.10398100316524506,
0.03887912631034851,
0.026873331516981125,
-0.022002601996064186,
-0.004452719818800688,
0.07187429815530777,
-0.0739731639623642,
0.022400720044970512,
0.008126473054289818,
0.013444476760923862,
-0.05247322842478752,
-0.028554605320096016,
-0.021028168499469757,
-0.04342300444841385,
-0.0025206664577126503,
0.009272423572838306,
0.016336714848876,
0.010619285516440868,
-0.03850063309073448,
-0.02824448235332966,
-0.056589525192976,
0.0075659858994185925,
0.047161929309368134,
-0.05803670361638069,
-0.08027305454015732,
-0.06768348813056946,
0.039778612554073334,
0.0683852881193161,
-0.034322384744882584,
0.00974276289343834,
-0.046464916318655014,
0.13138453662395477,
0.06945714354515076,
-0.08914849907159805,
-0.06601125746965408,
-0.04436146467924118,
0.059007249772548676,
0.011978932656347752,
0.010780911892652512,
-0.043096113950014114,
0.013533387333154678,
0.04134797677397728,
0.09085553884506226,
0.049203041940927505,
-0.010993742384016514,
-0.06418758630752563,
0.0059945485554635525,
0.05892330780625343,
0.037036024034023285,
0.08633149415254593,
-0.03448520228266716,
0.009371885098516941,
-0.05257291719317436,
-0.037018951028585434,
0.01652340590953827,
0.10523989051580429,
0.06360090523958206,
-0.00692747300490737,
-0.040654029697179794,
0.02209482714533806,
-0.023612359538674355,
-0.019499387592077255,
-0.06005141884088516,
-0.06050770729780197,
0.05348816141486168,
0.03648248687386513,
-0.029826175421476364,
0.04278230294585228,
0.033886201679706573,
0.053016506135463715,
0.05083844065666199,
0.013341506943106651,
-0.033359870314598083,
0.042888130992650986,
-0.0737932100892067,
-0.06268396228551865,
0.005396773107349873,
-0.044191375374794006,
-0.0013920365599915385,
-0.06321926414966583,
-0.014319689944386482,
0.004219755996018648,
-0.06711815297603607,
-0.0778040662407875,
-0.009994184598326683,
-0.06445430219173431,
-0.09659259021282196,
0.041950128972530365,
0.05887097492814064,
0.01766818016767502,
0.03878907486796379,
0.016544092446565628,
-0.023275326937437057,
0.09432851523160934,
-0.01652791164815426,
0.04321882873773575,
0.022619174793362617,
0.02713869884610176,
0.031209910288453102,
0.007967579178512096,
0.04065239056944847,
0.01522041391581297,
0.11717864871025085,
0.00714899692684412,
-0.05348784476518631,
1.3959479389079417e-33,
0.10042783617973328,
0.05446041747927666,
0.08401936292648315,
-0.04825631156563759,
0.003943173680454493,
-0.057064659893512726,
0.025173913687467575,
-0.03944699093699455,
0.01969626173377037,
-0.07419855892658234,
-0.06858805567026138,
0.027814768254756927,
0.0590549111366272,
-0.07808054983615875,
0.017191309481859207,
0.013468559831380844,
0.01925753615796566,
0.04827779158949852,
-0.06693793088197708,
-0.0838870033621788,
0.027207544073462486,
0.033127766102552414,
0.01842552237212658,
-0.04516640678048134,
-0.07240772247314453,
0.017567941918969154,
-0.05476909130811691,
0.009199951775372028,
-0.021589389070868492,
0.021157221868634224,
0.025468142703175545,
-0.011529200710356236,
0.08178601413965225,
0.047975052148103714,
-0.007556290365755558,
-0.0007370733073912561,
-0.0004919428611174226,
-0.020850464701652527,
0.05906477943062782,
0.04925799369812012,
-0.03250375762581825,
0.0007303815218620002,
0.08743916451931,
0.04526641219854355,
0.03385639935731888,
-0.06085516884922981,
-0.06740901619195938,
-0.08574718236923218,
-0.03912351652979851,
0.007088320329785347,
-0.07377580553293228,
-0.0030756364576518536,
-0.021846093237400055,
0.0037871503736823797,
0.09472420066595078,
-0.026888925582170486,
-0.047222986817359924,
0.1075904443860054,
0.00919971615076065,
0.056204840540885925,
0.022185230627655983,
-0.02568315900862217,
-0.01245813723653555,
0.08375727385282516,
-0.0787331834435463,
-0.031710848212242126,
-0.022529881447553635,
-0.0822451189160347,
-0.020372504368424416,
0.09695180505514145,
-0.025026723742485046,
0.01932230405509472,
-0.0074899932369589806,
0.0109285032376647,
-0.012394002638757229,
-0.028128301724791527,
0.09926508367061615,
0.07657969743013382,
-0.0021382535342127085,
0.1023465171456337,
-0.18296417593955994,
0.030953479930758476,
-0.14929717779159546,
-0.01526250783354044,
0.0017457508947700262,
-0.014950363896787167,
0.03685232996940613,
-0.07117787003517151,
0.02769480086863041,
0.003518443088978529,
0.09659509360790253,
-0.044454265385866165,
-0.02137276530265808,
-0.022257303819060326,
0.006954778917133808,
-2.5521898044801717e-33,
-0.020935136824846268,
-0.018601909279823303,
0.08052918314933777,
0.03121357597410679,
-0.03741541504859924,
0.046146757900714874,
-0.0433652438223362,
-0.04966143146157265,
-0.04666972905397415,
-0.003966917283833027,
0.03937586396932602,
0.09249644726514816,
-0.08745523542165756,
-0.03341703489422798,
-0.043032847344875336,
-0.045656684786081314,
0.0613618865609169,
-0.012627783231437206,
0.020816558972001076,
-0.04713323712348938,
0.052646372467279434,
0.04469332844018936,
-0.02651216834783554,
0.02780138887465,
-0.05674440786242485,
-0.01872986927628517,
-0.013419750146567822,
-0.014178796671330929,
0.04475320130586624,
-0.058777835220098495,
0.039944082498550415,
0.03985186666250229,
-0.11204558610916138,
-0.04253130406141281,
0.05825438350439072,
0.03788013011217117,
-0.009644240140914917,
-0.06554070115089417,
0.004128193482756615,
0.044021181762218475,
0.026843784376978874,
0.05461231246590614,
0.05992400273680687,
-0.023600157350301743,
-0.0040924157947301865,
0.001915535656735301,
0.06319651007652283,
0.004434162750840187,
0.08645909279584885,
-0.06259790062904358,
-0.042671360075473785,
-0.04362823814153671,
-0.016815723851323128,
0.005593861918896437,
0.006977460812777281,
-0.05333150923252106,
-0.051345158368349075,
0.025002697482705116,
-0.04449450597167015,
-0.002908238209784031,
0.07893701642751694,
-0.041901350021362305,
0.0028561761137098074,
-0.05840853229165077,
-0.07569762319326401,
0.08005391061306,
0.008128836750984192,
-0.002922928659245372,
0.006082892417907715,
0.012760546989738941,
-0.001987965777516365,
-0.08668648451566696,
-0.016887886449694633,
0.012319880537688732,
-0.08669650554656982,
0.037130843847990036,
0.02227688767015934,
0.014480475336313248,
0.02285933494567871,
-0.043243180960416794,
0.02535545825958252,
0.055741071701049805,
-0.09840162843465805,
-0.11282628774642944,
0.03972051292657852,
0.09949152916669846,
-0.009886731393635273,
-0.06434657424688339,
-0.04820767045021057,
-0.060513995587825775,
0.0010386448120698333,
-0.03668074309825897,
0.00710064172744751,
0.011042685247957706,
-0.021953372284770012,
-3.090555011908691e-8,
0.004692793358117342,
-0.04703304544091225,
-0.020473428070545197,
-0.0014076805673539639,
0.029495229944586754,
0.055440038442611694,
-0.02128630504012108,
-0.07060917466878891,
0.01279600989073515,
0.01177192386239767,
0.04128925874829292,
-0.023267805576324463,
0.0016366562340408564,
-0.03546653687953949,
-0.052626922726631165,
0.04666454344987869,
0.03384195268154144,
-0.005325752776116133,
-0.00566085334867239,
-0.02190009132027626,
-0.017130395397543907,
-0.017146041616797447,
0.01624288782477379,
-0.051015108823776245,
-0.05624674633145332,
0.06500033289194107,
0.04132705554366112,
0.0010483592050150037,
-0.016313878819346428,
-0.01784146949648857,
0.03863011673092842,
-0.09165627509355545,
-0.010227411054074764,
0.027792230248451233,
-0.004997525364160538,
0.026751570403575897,
0.0648108646273613,
0.0061746444553136826,
0.0070030647329986095,
0.013673685491085052,
0.07024706900119781,
-0.12441478669643402,
0.017031803727149963,
0.0365174375474453,
-0.10800210386514664,
0.042341455817222595,
-0.02982274815440178,
0.018545344471931458,
-0.03936095908284187,
-0.07744333893060684,
0.01569909229874611,
-0.1045655906200409,
0.003800346050411463,
-0.06301828473806381,
-0.05337843298912048,
0.1337691992521286,
0.036013275384902954,
0.007348500657826662,
0.022838715463876724,
0.022814588621258736,
0.07980132848024368,
-0.05071576312184334,
0.02510124072432518,
0.08293105661869049
] |
PMID:25838188 | In contrast, when we analyzed metastases based on anatomical site, we uncovered large differences in RSI. | [
0.023930203169584274,
-0.03753142058849335,
-0.007372885476797819,
-0.02837502770125866,
0.020736174657940865,
-0.0671694278717041,
-0.07948949933052063,
0.07387115806341171,
0.08336988836526871,
-0.00007009752880549058,
-0.053271930664777756,
0.038609523326158524,
0.00970781221985817,
0.08020669221878052,
-0.003957295790314674,
-0.09309538453817368,
-0.06076113134622574,
-0.0425712876021862,
-0.013021659106016159,
0.03388398140668869,
0.02534172311425209,
-0.006484035402536392,
0.0023760059848427773,
0.0014708653325214982,
0.02698022499680519,
-0.08968884497880936,
-0.01210646890103817,
0.052915554493665695,
-0.042530402541160583,
0.027780134230852127,
0.0462382473051548,
-0.05481132119894028,
-0.038279563188552856,
-0.04947727173566818,
-0.0271292757242918,
0.001769416849128902,
-0.031513363122940063,
0.09253644198179245,
0.03238324075937271,
-0.00017602638399694115,
0.02879181131720543,
-0.034987956285476685,
-0.07293067872524261,
-0.0436776801943779,
0.09451337903738022,
-0.03226080164313316,
-0.11176766455173492,
-0.06135597452521324,
-0.0390901193022728,
0.007259533740580082,
-0.12902496755123138,
-0.029012953862547874,
-0.07972102612257004,
0.12775392830371857,
0.017020469531416893,
-0.01856367103755474,
-0.027648523449897766,
-0.08255783468484879,
-0.0005476393271237612,
-0.06311037391424179,
-0.024263150990009308,
-0.023861197754740715,
0.032178256660699844,
0.030972043052315712,
0.09565199166536331,
0.06067899987101555,
0.02859157882630825,
-0.11618463695049286,
0.03527026250958443,
-0.014696845784783363,
0.04351375624537468,
0.05656121298670769,
-0.0419217050075531,
0.01922854408621788,
-0.05038708820939064,
0.03414114937186241,
-0.042782291769981384,
0.07318656891584396,
-0.03900769725441933,
-0.06094306707382202,
-0.012685858644545078,
0.05985654890537262,
-0.010380172170698643,
-0.021740054711699486,
-0.021513404324650764,
0.014243800193071365,
0.04446234181523323,
-0.006666672416031361,
-0.13734765350818634,
0.029488252475857735,
0.07574928551912308,
0.03790924698114395,
-0.01997082121670246,
-0.024600397795438766,
0.01697959378361702,
-0.02619999833405018,
0.014767701737582684,
0.02233739010989666,
0.08906809985637665,
-0.010053412057459354,
-0.055364012718200684,
-0.023266347125172615,
-0.0667988732457161,
0.007274835370481014,
-0.008113826625049114,
0.01712781935930252,
0.01209581270813942,
-0.020943840965628624,
-0.06373324990272522,
0.005255178548395634,
0.0642893835902214,
0.06019578501582146,
0.020880350843071938,
0.06491204351186752,
0.0609588660299778,
0.03949877992272377,
-0.03810726851224899,
0.09130273014307022,
0.045484062284231186,
0.0380769744515419,
0.010972024872899055,
-0.07607483863830566,
-0.014987723901867867,
0.031165683642029762,
0.06769868731498718,
0.020602894946932793,
-0.1269897073507309,
-2.4529389593494074e-33,
0.10333959013223648,
-0.020985037088394165,
0.01315275114029646,
0.011754277162253857,
0.025995107367634773,
0.05829879641532898,
-0.046714361757040024,
-0.09057113528251648,
0.05039393529295921,
0.03177971392869949,
0.012845548801124096,
0.10217487812042236,
0.06324030458927155,
-0.08558017015457153,
-0.04354013130068779,
0.031066318973898888,
-0.04236188158392906,
0.06406276673078537,
-0.064202681183815,
-0.11403954774141312,
0.040567874908447266,
0.019114088267087936,
0.010302041657269001,
-0.04341303929686546,
-0.06791099905967712,
0.006151377689093351,
-0.0865497812628746,
0.03852371126413345,
-0.050267960876226425,
0.016721578314900398,
-0.01377936452627182,
-0.029889564961194992,
-0.001343435957096517,
0.026619743555784225,
0.009285262785851955,
0.0020370359998196363,
0.06065971404314041,
-0.06225888058543205,
-0.015288207679986954,
-0.008507965132594109,
0.034086957573890686,
-0.0036774910986423492,
-0.02442760393023491,
-0.011479959823191166,
-0.025844626128673553,
-0.031018009409308434,
-0.044449519366025925,
-0.0229566041380167,
0.004570480901747942,
-0.008465243503451347,
-0.07663894444704056,
-0.013469498604536057,
0.07244431227445602,
-0.041794102638959885,
-0.0015282847452908754,
-0.01593666709959507,
-0.04301449656486511,
-0.02749715931713581,
-0.0066060773096978664,
0.088910311460495,
0.09480822831392288,
-0.011518039740622044,
0.010305279865860939,
0.049701910465955734,
-0.030749911442399025,
0.026856429874897003,
-0.0479993000626564,
-0.0717400461435318,
-0.02028292417526245,
0.10463311523199081,
-0.01680314540863037,
0.029369352385401726,
0.05027511715888977,
0.010802052915096283,
-0.04377598688006401,
-0.038928158581256866,
-0.005587527062743902,
0.04568174108862877,
-0.0834636464715004,
0.02714630775153637,
-0.08064056187868118,
-0.005719635635614395,
-0.1282069832086563,
0.04075348377227783,
0.050262823700904846,
-0.046654507517814636,
-0.003144451417028904,
-0.010748974978923798,
-0.01916755735874176,
-0.0325222872197628,
0.06878776848316193,
0.015561485663056374,
0.01373223029077053,
0.00976219866424799,
-0.04939772188663483,
-9.618470586988867e-34,
-0.07574453949928284,
-0.03388224169611931,
0.06431864947080612,
-0.030498357489705086,
-0.0218728706240654,
0.05965358763933182,
0.02612973190844059,
0.0020349854603409767,
0.004858527798205614,
-0.01296766847372055,
0.03990582004189491,
0.07942796498537064,
-0.0028069682884961367,
-0.04210933670401573,
-0.005086828488856554,
-0.022185171023011208,
0.03376242145895958,
-0.046998530626297,
0.03835558518767357,
0.037781670689582825,
0.00646187225356698,
0.07337796688079834,
-0.020064841955900192,
0.006749880500137806,
-0.024925407022237778,
0.061765365302562714,
-0.016882751137018204,
0.02084357663989067,
-0.061818551272153854,
-0.04018031060695648,
-0.0012756858486682177,
0.036974869668483734,
-0.11977925151586533,
-0.09543769061565399,
-0.0401669479906559,
0.08684095740318298,
-0.041222795844078064,
-0.10752615332603455,
0.07157444208860397,
0.04742959886789322,
-0.01686645671725273,
0.007818745449185371,
0.08840557187795639,
0.0019031648989766836,
-0.016276054084300995,
-0.027474401518702507,
0.03710458055138588,
0.05554141476750374,
0.03576204553246498,
-0.04085639491677284,
-0.005263529252260923,
0.0077667622826993465,
-0.026011569425463676,
-0.04590394347906113,
0.015373900532722473,
-0.050116389989852905,
-0.061696890741586685,
-0.01941150240600109,
-0.0388600155711174,
-0.05191705748438835,
0.042566101998090744,
-0.07212334871292114,
-0.05880802124738693,
0.058717839419841766,
-0.07420694082975388,
0.05158692225813866,
0.10363367944955826,
-0.1326257586479187,
0.04307929053902626,
0.03660332411527634,
0.06896030157804489,
-0.08530911058187485,
-0.0067262290976941586,
0.06990071386098862,
0.029669396579265594,
-0.003522721352055669,
-0.02355184033513069,
0.04117033630609512,
-0.0069368756376206875,
0.010710684582591057,
0.020689282566308975,
0.04617299512028694,
-0.01674463227391243,
-0.1205623522400856,
0.03229117393493652,
0.09438019245862961,
-0.07217904180288315,
0.05865754932165146,
-0.01290625799447298,
-0.05171070992946625,
0.009908296167850494,
0.011293078772723675,
0.005209752824157476,
-0.008231553249061108,
0.01622660644352436,
-2.4790420383169476e-8,
0.06425206363201141,
-0.08801250904798508,
0.04385461285710335,
-0.01593889482319355,
-0.0323050357401371,
-0.04292165860533714,
-0.04422060027718544,
0.05114665627479553,
-0.021619580686092377,
-0.003222902538254857,
0.0652303546667099,
-0.010084998793900013,
-0.005844293162226677,
-0.06402777135372162,
0.01405361294746399,
0.04716372862458229,
-0.03636521100997925,
0.052406445145606995,
0.004152051638811827,
-0.03382044658064842,
-0.0015751344617456198,
-0.0014825400430709124,
0.0003214312018826604,
0.002682650927454233,
0.06282337009906769,
0.07355815917253494,
-0.005125383380800486,
0.013324854895472527,
-0.09513776004314423,
-0.02996012382209301,
0.11439433693885803,
-0.06101342290639877,
0.05086192861199379,
0.03235767409205437,
0.014675106853246689,
0.055599432438611984,
0.07089024037122726,
0.043856676667928696,
-0.004595148842781782,
0.016189787536859512,
0.01151406578719616,
-0.0883665680885315,
-0.016462627798318863,
0.015316933393478394,
-0.021033111959695816,
0.0700269490480423,
-0.015974869951605797,
0.08096984028816223,
0.010962204076349735,
-0.09406743943691254,
0.005249126814305782,
-0.1025630384683609,
-0.024163343012332916,
-0.002592630684375763,
-0.027147814631462097,
0.06213831901550293,
0.0033863941207528114,
0.029439294710755348,
0.11419937014579773,
0.05490564927458763,
0.12128020077943802,
0.03378699719905853,
-0.05768691375851631,
-0.08115991204977036
] |
PMID:25838188 | The median RSIs for metastases in descending order of radiation resistance were ovary (0.48), abdomen (0.47), liver (0.43), brain (0.42), lung (0.32), and lymph nodes (0.31) (P<.0001). | [
0.059831324964761734,
-0.012555918656289577,
-0.03632189333438873,
-0.008655017241835594,
0.02751419134438038,
-0.05846088007092476,
-0.034554511308670044,
0.12875989079475403,
-0.009772139601409435,
0.0834837332367897,
-0.029258504509925842,
0.03438558429479599,
0.08275961875915527,
0.012394039891660213,
-0.018242409452795982,
-0.027616353705525398,
-0.019141994416713715,
-0.05783894285559654,
-0.0009376184898428619,
0.015644505620002747,
-0.04407530277967453,
-0.014611460268497467,
0.04593416675925255,
0.0038161948323249817,
0.08106857538223267,
-0.11557641625404358,
-0.06836948543787003,
0.04427943378686905,
-0.05203079432249069,
0.0311018917709589,
0.0059686447493731976,
-0.056822020560503006,
-0.01942967250943184,
0.023924920707941055,
-0.01235355343669653,
-0.07799234241247177,
0.03539283573627472,
0.028891196474432945,
-0.02029288373887539,
0.01751106232404709,
-0.05401642620563507,
-0.048248305916786194,
-0.07699830085039139,
-0.014401188120245934,
0.006563267670571804,
0.0025272953789681196,
-0.08265615254640579,
-0.08624876290559769,
0.010890521109104156,
0.03973439708352089,
-0.09185504913330078,
-0.046745192259550095,
-0.11668910086154938,
0.1836516261100769,
0.008786658756434917,
-0.08545389026403427,
-0.08326534181833267,
-0.08572237938642502,
0.02062911167740822,
-0.031563036143779755,
-0.04973063990473747,
-0.05474165827035904,
0.04701979085803032,
0.060656819492578506,
0.09354951977729797,
0.05491270869970322,
-0.03260011598467827,
-0.06752751022577286,
0.0040465365163981915,
0.08732357621192932,
0.10044339299201965,
0.04645565524697304,
-0.03590066358447075,
-0.04676408693194389,
-0.01126863807439804,
0.005841514561325312,
0.0037607329431921244,
0.02342141605913639,
-0.016490120440721512,
-0.07415683567523956,
-0.06637250632047653,
0.02092709019780159,
-0.05382448807358742,
0.05318911746144295,
-0.07347012311220169,
-0.02557794749736786,
0.059556372463703156,
0.03847771883010864,
-0.09090539813041687,
0.03669078275561333,
-0.02357712760567665,
0.004303867928683758,
-0.03552909195423126,
0.0009067842038348317,
0.02298811264336109,
0.02223886363208294,
0.015731850638985634,
-0.07533279806375504,
-0.0035041370429098606,
-0.03163127228617668,
-0.06144906207919121,
-0.008440468460321426,
-0.009464539587497711,
0.02487320266664028,
-0.06514687091112137,
-0.025555642321705818,
-0.03461433947086334,
-0.02417025901377201,
-0.1308310180902481,
-0.03124137409031391,
0.06408238410949707,
0.07867846637964249,
0.0034714634530246258,
0.0563337504863739,
0.015941405668854713,
0.011236591264605522,
0.04963264241814613,
0.07494935393333435,
0.0030590405222028494,
-0.023207474499940872,
-0.012231660075485706,
0.0071031032130122185,
0.0008950028568506241,
0.035618316382169724,
0.08374665677547455,
0.035384245216846466,
-0.015199226327240467,
-9.158830255298275e-34,
0.06133067607879639,
0.03226200118660927,
0.08124130219221115,
-0.062047410756349564,
-0.053447458893060684,
0.017446156591176987,
0.048406582325696945,
-0.09837393462657928,
0.022850917652249336,
-0.021008891984820366,
0.010238896124064922,
0.056783657521009445,
0.06579408794641495,
-0.08864392340183258,
-0.007927067577838898,
-0.02551581710577011,
0.017074739560484886,
0.030278393998742104,
-0.09982476383447647,
-0.05530886724591255,
0.021763509139418602,
-0.030257701873779297,
-0.02240576781332493,
0.017893852666020393,
-0.01170134823769331,
0.032691460102796555,
-0.07420486956834793,
0.01570720225572586,
-0.0642535388469696,
0.023947494104504585,
0.015735771507024765,
-0.005703899078071117,
0.04390587657690048,
0.0710759311914444,
-0.03242097795009613,
-0.021996995434165,
-0.004908127244561911,
0.0498645082116127,
0.04756632447242737,
0.06808497756719589,
0.04176056757569313,
-0.024103526026010513,
0.04717141017317772,
0.014952685683965683,
-0.010665414854884148,
-0.0933651328086853,
-0.04551943019032478,
-0.017506388947367668,
0.05119413137435913,
0.015756135806441307,
-0.09261038899421692,
-0.009116929024457932,
0.028605006635189056,
-0.014820835553109646,
0.06510377675294876,
-0.04557240009307861,
-0.04757824167609215,
0.0093159731477499,
-0.06589823961257935,
0.06972171366214752,
0.04840253293514252,
-0.07028654217720032,
0.01069982536137104,
0.08389244973659515,
-0.036531299352645874,
-0.04421171173453331,
-0.07236620783805847,
-0.10045848041772842,
-0.05724906176328659,
0.11419565975666046,
-0.01420130580663681,
0.04722516983747482,
0.023595042526721954,
-0.0020956534426659346,
0.008543589152395725,
0.05695037171244621,
0.039822109043598175,
0.026424303650856018,
-0.015664126724004745,
0.05313708633184433,
-0.052369095385074615,
0.025163358077406883,
-0.08758718520402908,
-0.007372486405074596,
0.11135689169168472,
-0.03152136504650116,
0.013076604343950748,
-0.057848043739795685,
0.002352812560275197,
-0.015124620869755745,
0.07055747509002686,
-0.05403665453195572,
0.006850855425000191,
0.02898036502301693,
-0.02997809462249279,
-7.788103741548675e-34,
-0.04105481132864952,
-0.003188889240846038,
0.10102180391550064,
0.017356030642986298,
0.012210555374622345,
0.0807475745677948,
-0.008060295134782791,
0.057511791586875916,
-0.025462066754698753,
0.055003128945827484,
0.058924805372953415,
0.041276492178440094,
-0.07724650204181671,
-0.061384256929159164,
0.020422985777258873,
-0.07664071023464203,
0.1069771870970726,
-0.05286266282200813,
0.07355976104736328,
-0.0283467136323452,
0.007637825328856707,
0.08390248566865921,
0.06242010369896889,
0.026118827983736992,
0.0035809704568237066,
0.019387805834412575,
0.004948639776557684,
0.009274586103856564,
-0.031885817646980286,
-0.054841164499521255,
-0.001525134895928204,
0.07297074794769287,
-0.06535698473453522,
-0.00826377421617508,
0.025216547772288322,
0.025804681703448296,
-0.022260259836912155,
-0.025108477100729942,
0.014986148104071617,
0.054342467337846756,
-0.01847044564783573,
0.004291682504117489,
0.04055006429553032,
0.02582409605383873,
-0.02697681449353695,
-0.006383922416716814,
0.06963913142681122,
0.06984769552946091,
0.08492792397737503,
-0.042056214064359665,
-0.0380193293094635,
-0.005569975823163986,
-0.024579865857958794,
0.0347951278090477,
0.05964304879307747,
-0.03744833171367645,
-0.0599229522049427,
0.01699877344071865,
0.021681025624275208,
-0.08234564960002899,
0.06786887347698212,
-0.05888711288571358,
-0.024209678173065186,
-0.04192347824573517,
-0.029494553804397583,
0.10365699231624603,
0.05425560474395752,
-0.04571811109781265,
-0.012584700249135494,
0.048000991344451904,
0.04089788720011711,
-0.05943358317017555,
-0.014615374617278576,
-0.0351761132478714,
0.022581888362765312,
0.0022427740041166544,
-0.021008603274822235,
0.06843944638967514,
0.057803764939308167,
-0.0333876833319664,
-0.026204215362668037,
0.05629732087254524,
-0.011726790107786655,
-0.09721341729164124,
0.03364476561546326,
0.02488688938319683,
-0.077984519302845,
-0.029160428792238235,
-0.008524533361196518,
-0.04673116281628609,
-0.02339186891913414,
0.01763501949608326,
0.020723707973957062,
-0.01881629414856434,
-0.005133247468620539,
-4.0991551486513345e-8,
0.008314637467265129,
-0.057984527200460434,
-0.03550340607762337,
0.018647797405719757,
0.04485784098505974,
0.018463127315044403,
0.011569906026124954,
0.023169267922639847,
0.015170453116297722,
0.03768786042928696,
0.029511427506804466,
0.04754434525966644,
0.10293863713741302,
-0.09313888847827911,
-0.02160458452999592,
0.015202641487121582,
0.021782871335744858,
0.03997784107923508,
0.009776637889444828,
-0.08833771198987961,
-0.024801943451166153,
-0.06151201203465462,
0.011172342114150524,
-0.0006951115792617202,
-0.029767896980047226,
0.09465441852807999,
0.10302594304084778,
-0.03403564915060997,
-0.004319450352340937,
-0.030635787174105644,
0.05746375024318695,
-0.0892292782664299,
0.019333122298121452,
0.0058150021359324455,
-0.07871351391077042,
0.02310505136847496,
0.05255735665559769,
0.06375829875469208,
0.007698345463722944,
0.018892597407102585,
0.03017515316605568,
-0.0687328353524208,
0.037650227546691895,
0.022400718182325363,
-0.06970413029193878,
0.07165732234716415,
-0.046311985701322556,
0.04750768467783928,
0.006565745919942856,
-0.12259825319051743,
-0.0004637023084796965,
-0.14707273244857788,
0.0208963043987751,
-0.05738089978694916,
-0.09651051461696625,
0.07455898821353912,
0.07127402722835541,
-0.027251718565821648,
0.017125841230154037,
0.021287892013788223,
0.03021225519478321,
0.016262013465166092,
-0.027456145733594894,
0.02393612079322338
] |
PMID:25838188 | These findings were confirmed when the analysis was restricted to lesions from the same patient (n=139). | [
0.00027121073799207807,
0.02726164646446705,
-0.0342407263815403,
-0.003492178628221154,
-0.06312486529350281,
-0.023534351959824562,
-0.016202494502067566,
0.09089387208223343,
-0.013249749317765236,
-0.0708586648106575,
0.036182601004838943,
0.03781556338071823,
-0.01866886205971241,
0.04442717134952545,
-0.13291868567466736,
-0.01182949636131525,
-0.008667606860399246,
-0.05516296625137329,
0.005799988284707069,
-0.004575103521347046,
-0.0389876589179039,
0.02832217514514923,
0.03812836855649948,
-0.010632757097482681,
-0.012144334614276886,
0.004345056600868702,
-0.003605068428441882,
-0.018026763573288918,
0.06232922896742821,
0.034141335636377335,
0.005318901967257261,
-0.004196616820991039,
-0.00013193611812312156,
0.027002345770597458,
0.04074675589799881,
-0.05954748019576073,
-0.07120292633771896,
0.014407514594495296,
-0.00834907777607441,
0.01526985876262188,
0.014476442709565163,
-0.037535760551691055,
0.014298422262072563,
-0.0025537193287163973,
-0.020162256434559822,
-0.07277877628803253,
-0.11244402080774307,
-0.031158529222011566,
0.00589677132666111,
0.055014099925756454,
-0.017359783872961998,
-0.014759288169443607,
-0.02091054618358612,
0.088600754737854,
-0.03062165528535843,
-0.07519136369228363,
-0.06901625543832779,
-0.04640438035130501,
-0.008301938883960247,
0.04593076556921005,
0.003453303361311555,
-0.03136453405022621,
-0.009487682022154331,
0.01894768327474594,
0.09812154620885849,
0.018804047256708145,
-0.00961923785507679,
-0.16756397485733032,
0.030780134722590446,
0.06673821806907654,
0.0706029012799263,
-0.005322749726474285,
0.022000258788466454,
0.02377246506512165,
-0.05997785925865173,
0.013270835392177105,
0.013353257440030575,
0.038289155811071396,
0.022866705432534218,
-0.11231227219104767,
0.0057847341522574425,
0.051511894911527634,
0.027477040886878967,
-0.0427861362695694,
-0.03239810839295387,
0.0024818708188831806,
-0.017420396208763123,
-0.00013773349928669631,
-0.10731896758079529,
0.04221856966614723,
0.07945729792118073,
-0.02053140103816986,
-0.03256049007177353,
-0.023730259388685226,
-0.006298807915300131,
-0.03889335319399834,
0.0003471732197795063,
-0.00005564454841078259,
0.10652803629636765,
0.005431081168353558,
-0.03651883080601692,
-0.026747561991214752,
0.06487202644348145,
0.06352045387029648,
-0.04791569709777832,
-0.017409680411219597,
0.02194949798285961,
-0.1367778331041336,
-0.0008070748299360275,
-0.013391457498073578,
0.030229482799768448,
0.07639781385660172,
0.08192615956068039,
0.005752325989305973,
0.04019637405872345,
0.011579681187868118,
-0.07035625725984573,
0.02936910092830658,
0.018664022907614708,
0.05308043956756592,
-0.013108369894325733,
-0.06638778001070023,
0.04642895981669426,
-0.07017111033201218,
0.07173709571361542,
0.06665599346160889,
-0.10706166923046112,
-4.394196248045412e-33,
0.06516320258378983,
-0.11686532199382782,
-0.01664121076464653,
0.02223561517894268,
0.031108558177947998,
0.11041998118162155,
-0.03402787074446678,
-0.04813326895236969,
0.018373914062976837,
-0.03852878510951996,
0.032784901559352875,
0.009911824949085712,
0.11335279792547226,
-0.010439352132380009,
-0.079616017639637,
0.11799533665180206,
0.08968401700258255,
0.08385849744081497,
-0.09463223069906235,
-0.01765822060406208,
0.0072296857833862305,
0.007313928101211786,
-0.0024805967696011066,
0.016569050028920174,
-0.08755489438772202,
-0.006536172702908516,
-0.06079750508069992,
0.0016094740713015199,
0.06043020635843277,
0.007122913375496864,
-0.05968814715743065,
0.06405466049909592,
0.018719376996159554,
0.04679045081138611,
-0.012297230772674084,
0.10352277010679245,
0.0588652640581131,
0.02295161411166191,
0.08882718533277512,
0.06632048636674881,
0.07080396264791489,
0.0137961870059371,
0.015815136954188347,
-0.028621412813663483,
-0.01977367140352726,
-0.010603070259094238,
-0.058527253568172455,
-0.016042198985815048,
-0.03239218518137932,
0.007052264176309109,
-0.030732106417417526,
0.04571160301566124,
-0.046609628945589066,
-0.07360804080963135,
0.0268520750105381,
0.05841296166181564,
-0.03883695974946022,
0.016964545473456383,
0.03804900497198105,
0.04098038375377655,
0.14563201367855072,
0.03539405018091202,
0.03446442633867264,
-0.021466508507728577,
-0.059343643486499786,
-0.04551353305578232,
-0.07364170253276825,
-0.04367700219154358,
-0.008144904859364033,
0.0247137900441885,
-0.08127692341804504,
0.0319371335208416,
0.08164836466312408,
-0.012347445823252201,
0.0005768816918134689,
-0.06584998965263367,
0.0032430673018097878,
0.06207951158285141,
-0.05091775581240654,
-0.021897735074162483,
-0.052995435893535614,
-0.000920240709092468,
-0.00646097119897604,
0.005504598841071129,
-0.07011507451534271,
0.024026764556765556,
-0.03169992193579674,
0.05534029006958008,
-0.07562977820634842,
0.02337701991200447,
0.08471270650625229,
0.016591500490903854,
-0.06558014452457428,
-0.034009091556072235,
0.010493787005543709,
7.760381819500943e-35,
-0.10534323006868362,
0.06227734312415123,
-0.06954959779977798,
-0.045006781816482544,
0.012662899680435658,
0.04117923229932785,
0.010346703231334686,
0.05272519215941429,
-0.024018697440624237,
-0.0352570004761219,
0.10509689152240753,
-0.0010004107607528567,
-0.012815358117222786,
-0.10471399128437042,
-0.10996287316083908,
-0.0010941296350210905,
-0.07590974867343903,
0.038219429552555084,
-0.014592275954782963,
0.028445325791835785,
-0.024742241948843002,
0.024953100830316544,
-0.020811457186937332,
-0.001549511682242155,
-0.011708280071616173,
0.04245198518037796,
0.005167637951672077,
-0.026611605659127235,
-0.06794420629739761,
-0.035343237221241,
0.0023206828627735376,
0.0937456339597702,
-0.10319039970636368,
-0.04426700994372368,
0.04293457046151161,
-0.039358533918857574,
0.08024562895298004,
-0.07155969738960266,
-0.018809810280799866,
-0.05985883250832558,
0.05205358937382698,
-0.014072518795728683,
0.02881992980837822,
0.04984563589096069,
0.014837859198451042,
0.019762733951210976,
0.022011704742908478,
-0.04679711163043976,
0.0640593022108078,
0.02330654114484787,
0.027489613741636276,
0.0631265938282013,
0.023524029180407524,
0.01771855726838112,
0.012500195764005184,
-0.019370537251234055,
0.004664427135139704,
-0.02967681922018528,
-0.02380237728357315,
0.0949968621134758,
0.018429359421133995,
0.018929174169898033,
-0.15860795974731445,
0.024283070117235184,
0.08097890019416809,
0.07709331065416336,
-0.01594359241425991,
-0.02080676332116127,
0.07722924649715424,
0.0024957850109785795,
-0.06602497398853302,
-0.06275144964456558,
-0.02824397198855877,
-0.027469025924801826,
0.01489575207233429,
-0.010907124727964401,
-0.02140958607196808,
-0.08625322580337524,
-0.0038431354332715273,
0.03720520809292793,
-0.055051110684871674,
-0.062098074704408646,
0.05576552450656891,
0.03201783820986748,
-0.005994788836687803,
0.03062339313328266,
-0.030532926321029663,
-0.08391059190034866,
-0.05225629359483719,
0.011370472609996796,
0.015362586826086044,
-0.08725123852491379,
-0.14397047460079193,
-0.12216506898403168,
0.02780190110206604,
-2.8999782131222673e-8,
0.0030539531726390123,
-0.08715146034955978,
-0.006806601770222187,
-0.020245324820280075,
0.03772687539458275,
-0.0338720940053463,
-0.07384950667619705,
0.06690184772014618,
-0.014883549883961678,
0.05401056259870529,
-0.026763102039694786,
-0.026871457695961,
-0.02538849040865898,
0.004983298480510712,
0.026565397158265114,
-0.052375372499227524,
0.02278570830821991,
0.01117642130702734,
-0.05253111571073532,
-0.003257805947214365,
-0.03811061754822731,
-0.006379209458827972,
0.09156733006238937,
-0.0047795455902814865,
-0.04302011802792549,
0.024711938574910164,
-0.0022887862287461758,
0.09072831273078918,
-0.09570913016796112,
-0.05684865638613701,
-0.0036653296556323767,
-0.013923097401857376,
-0.01873132772743702,
-0.04037408158183098,
0.02968619205057621,
-0.016302427276968956,
0.06468518823385239,
0.02575310505926609,
0.04408092796802521,
0.10053098201751709,
0.01721908338367939,
-0.06557438522577286,
0.021328790113329887,
0.042349930852651596,
-0.017629243433475494,
-0.014698058366775513,
-0.004214308690279722,
-0.014324451796710491,
0.06433044373989105,
-0.03812527656555176,
0.006462262477725744,
-0.01002184022217989,
0.06160992756485939,
0.018340615555644035,
-0.05998678877949715,
0.07428400963544846,
0.06093069538474083,
0.05645846948027611,
0.007518225349485874,
0.03898997977375984,
0.029242422431707382,
-0.02189033292233944,
0.037881072610616684,
-0.028408432379364967
] |
PMID:25838188 | In our independent cohort of treated lung and liver metastases, lung metastases had an improved local control rate compared to that in patients with liver metastases (2-year local control rate of 100% vs 73.0%, respectively; P=.026). | [
0.13638794422149658,
0.008953551761806011,
-0.01580888219177723,
-0.0124782994389534,
0.02136017195880413,
0.007278485223650932,
-0.09631035476922989,
0.10257963091135025,
0.05834502354264259,
0.03309188410639763,
-0.007551956456154585,
0.014715169556438923,
-0.016113653779029846,
0.02701667882502079,
-0.014846442267298698,
0.05284396931529045,
0.06873735785484314,
-0.0838523730635643,
-0.047430187463760376,
0.023768838495016098,
-0.08169995248317719,
-0.014638022519648075,
0.11689570546150208,
0.01479867659509182,
0.05340038239955902,
-0.049034155905246735,
-0.07478178292512894,
-0.002918847603723407,
0.009159614332020283,
0.010703745298087597,
0.0015963054029271007,
-0.02590940147638321,
-0.04118729010224342,
-0.06798447668552399,
-0.11289157718420029,
-0.043295398354530334,
-0.036743272095918655,
0.11596526205539703,
-0.0701325535774231,
0.06065459921956062,
-0.014346256852149963,
0.05849866941571236,
-0.049184877425432205,
-0.021414097398519516,
-0.02495642378926277,
0.011172090657055378,
-0.10805404931306839,
0.07880572229623795,
-0.06543663144111633,
0.11824966222047806,
-0.04050689563155174,
0.023852063342928886,
-0.049302853643894196,
0.043835967779159546,
0.05301617458462715,
-0.010506104677915573,
0.009566797874867916,
-0.05205083265900612,
0.027169058099389076,
-0.11298945546150208,
-0.13143256306648254,
-0.043448347598314285,
-0.022433731704950333,
-0.0100703788921237,
0.04406362771987915,
0.05499644950032234,
-0.007709139958024025,
-0.084806427359581,
-0.04834277555346489,
-0.022597774863243103,
0.018685409799218178,
0.04814746603369713,
0.04052475467324257,
0.05063866823911667,
-0.04242222011089325,
0.004417567979544401,
-0.01266479305922985,
0.0040017119608819485,
0.039073552936315536,
0.005949452519416809,
0.019964292645454407,
-0.004763537552207708,
-0.011461252346634865,
-0.0446770079433918,
-0.041246447712183,
-0.06836576759815216,
-0.02133278176188469,
0.006371552590280771,
0.0020646254997700453,
-0.001860767137259245,
0.02629631944000721,
0.06511019170284271,
0.014689288102090359,
-0.060144100338220596,
-0.01711052842438221,
0.02500765211880207,
-0.01725250482559204,
0.045710768550634384,
0.006547314114868641,
-0.06132964789867401,
0.05257590487599373,
-0.03970428556203842,
-0.07313938438892365,
0.0229608416557312,
-0.0075240470468997955,
-0.02396007627248764,
-0.010768863372504711,
0.03202781081199646,
-0.03794027492403984,
0.10270556062459946,
0.0636042132973671,
0.031931061297655106,
-0.035686999559402466,
-0.024338291957974434,
0.024316787719726562,
0.13007886707782745,
0.010159425437450409,
-0.02187580242753029,
0.049533285200595856,
0.011633024550974369,
-0.03673691302537918,
-0.062262095510959625,
0.028159908950328827,
-0.032877612859010696,
0.05792209878563881,
-0.010163784958422184,
-0.020257141441106796,
1.1607953449782318e-33,
0.09371001273393631,
-0.002657766453921795,
-0.060728222131729126,
0.02002595365047455,
0.05323091521859169,
-0.012206071987748146,
0.02780376933515072,
-0.0121849300339818,
0.015862703323364258,
-0.0783277377486229,
0.042149100452661514,
0.017320388928055763,
-0.013332722708582878,
-0.04761477932333946,
-0.03416956961154938,
0.021675243973731995,
0.00018570756947156042,
0.0013037719763815403,
-0.058820366859436035,
-0.05235353112220764,
-0.002961442805826664,
-0.007794109173119068,
-0.0007597064832225442,
-0.029943885281682014,
0.005629206541925669,
-0.018485261127352715,
-0.05436106398701668,
0.0927467793226242,
-0.09126026928424835,
-0.01746518909931183,
0.05020085349678993,
0.02147812955081463,
0.06434871256351471,
0.018411101773381233,
-0.017811650410294533,
0.037308480590581894,
-0.047908391803503036,
0.02202749066054821,
0.05193078890442848,
0.056513622403144836,
-0.011304302141070366,
-0.0012380157131701708,
0.012010159902274609,
-0.03902352601289749,
-0.0011817251797765493,
-0.11280237883329391,
-0.1388222724199295,
-0.016473207622766495,
-0.14110510051250458,
-0.001694358536042273,
-0.02134973369538784,
0.012348324060440063,
-0.025042971596121788,
-0.011428597383201122,
0.11043453961610794,
-0.011971703730523586,
-0.06714282929897308,
0.009297814220190048,
-0.0673055425286293,
0.06058930605649948,
0.12477521598339081,
-0.010444121435284615,
0.001989166485145688,
0.09922822564840317,
-0.06063978374004364,
0.005257806740701199,
0.0007096431218087673,
-0.02132190577685833,
-0.030814437195658684,
0.08829602599143982,
-0.04050951078534126,
0.0016157911159098148,
-0.0034360899589955807,
0.05248952656984329,
-0.054062359035015106,
-0.08818864822387695,
0.08328888565301895,
0.0039163255132734776,
-0.10565894842147827,
0.054059553891420364,
0.009803405031561852,
-0.042655572295188904,
-0.1812615990638733,
0.0612696148455143,
0.023198114708065987,
-0.09802813827991486,
-0.00012335219071246684,
-0.022188203409314156,
-0.05114780738949776,
-0.025647541508078575,
0.016880899667739868,
-0.06664042174816132,
0.002689661690965295,
0.07338114827871323,
-0.0029765937943011522,
-5.406852305184165e-33,
-0.012001954950392246,
-0.019757600501179695,
0.0638468787074089,
0.03169075772166252,
0.01058098953217268,
0.06111375615000725,
0.039312057197093964,
-0.0622364766895771,
0.0028077021706849337,
-0.019039064645767212,
-0.052948247641325,
0.0649118646979332,
-0.012783887796103954,
-0.023548388853669167,
-0.006479501258581877,
-0.06179280951619148,
0.052048131823539734,
-0.05968090891838074,
0.023063506931066513,
-0.014617028646171093,
-0.029931234195828438,
0.004658783785998821,
-0.010030643083155155,
0.06224300339818001,
-0.13285580277442932,
-0.06944870948791504,
-0.08655927330255508,
0.030047699809074402,
-0.015047643333673477,
-0.03852738440036774,
-0.0764349102973938,
0.04684232920408249,
-0.006155513226985931,
0.04696619138121605,
-0.031159929931163788,
0.07489990442991257,
0.021748041734099388,
-0.05994269251823425,
0.05354004725813866,
0.04303932934999466,
0.0013802627800032496,
0.019869493320584297,
-0.016891425475478172,
0.03209860622882843,
0.049662135541439056,
0.06853024661540985,
0.05259346216917038,
-0.07739876210689545,
-0.015332631766796112,
-0.07542239874601364,
-0.03437430411577225,
0.03312061354517937,
-0.03179749846458435,
0.06525154411792755,
-0.030651578679680824,
-0.01581181026995182,
-0.05315204709768295,
-0.02825692482292652,
0.005508883856236935,
0.0103548439219594,
-0.03305397555232048,
0.034677404910326004,
-0.06195851042866707,
0.009366682730615139,
-0.041779644787311554,
0.09142852574586868,
0.0372028648853302,
-0.059308335185050964,
0.06630252301692963,
0.0344134196639061,
-0.07125860452651978,
-0.1066681444644928,
-0.051244981586933136,
0.04740101471543312,
0.004828204866498709,
0.009409124031662941,
0.05637277662754059,
0.02483132854104042,
-0.04035161808133125,
-0.0016437472077086568,
-0.019893500953912735,
0.051040083169937134,
0.03346098214387894,
-0.10248006135225296,
-0.00004240512862452306,
0.018318403512239456,
-0.07831433415412903,
0.013473591767251492,
-0.04401146620512009,
0.03300901874899864,
-0.01874636486172676,
0.018974829465150833,
-0.032330337911844254,
-0.10200721770524979,
-0.032319653779268265,
-4.046765056386903e-8,
-0.011231457814574242,
0.02418406307697296,
0.07418861985206604,
0.046136099845170975,
-0.04362110048532486,
0.06456177681684494,
0.0010741794249042869,
-0.013087192550301552,
-0.05531701445579529,
0.027545981109142303,
0.0829959437251091,
0.06651996821165085,
-0.010626798495650291,
-0.0943651795387268,
0.034815218299627304,
0.006445310544222593,
-0.022741425782442093,
0.07498043030500412,
0.05668787658214569,
0.007765491958707571,
-0.013359454460442066,
0.011483515612781048,
0.06769900768995285,
-0.053074371069669724,
-0.025130122900009155,
0.0434010811150074,
0.011249647475779057,
0.10103052109479904,
-0.019323773682117462,
0.07456744462251663,
-0.004295130260288715,
-0.035048726946115494,
0.050662606954574585,
-0.0041868616826832294,
0.05865516513586044,
-0.047788869589567184,
-0.020913688465952873,
-0.030335772782564163,
0.03718237206339836,
0.0624835304915905,
0.04799298942089081,
0.026464300230145454,
-0.06629585474729538,
0.019023224711418152,
-0.0405232198536396,
0.024370383471250534,
-0.04916583001613617,
0.021541345864534378,
-0.006215558387339115,
-0.023009629920125008,
0.037185993045568466,
-0.058729637414216995,
0.014685871079564095,
-0.0345938466489315,
0.03227672725915909,
0.09205827116966248,
0.012783460319042206,
-0.06301409751176834,
0.02150624804198742,
0.03149079531431198,
0.000490504433400929,
0.0649455264210701,
-0.07444337755441666,
-0.06862964481115341
] |
PMID:25838188 | Assessment of radiation sensitivity between primary and metastatic tissues of colon cancer histology revealed significant differences based on anatomical location of metastases. | [
0.12811671197414398,
-0.02486668899655342,
-0.024819154292345047,
-0.05648724362254143,
-0.024684179574251175,
-0.10180872678756714,
-0.008310789242386818,
0.05930545926094055,
0.031196637079119682,
0.03154657036066055,
0.0048101660795509815,
-0.011535778641700745,
0.03500375151634216,
0.0899871215224266,
-0.060536038130521774,
-0.07830581068992615,
0.03693376109004021,
-0.04614940285682678,
-0.003501264378428459,
0.01563728041946888,
-0.06933603435754776,
-0.011884928680956364,
0.02420978434383869,
-0.025596505030989647,
0.014762486331164837,
-0.08831135928630829,
0.029078472405672073,
0.04855675250291824,
-0.06876277178525925,
0.026933301240205765,
0.021726690232753754,
-0.056915055960416794,
0.022342177107930183,
-0.013477290980517864,
0.04025116562843323,
-0.039816856384277344,
0.033448293805122375,
0.0825347751379013,
-0.007114821579307318,
0.013503837399184704,
-0.051722295582294464,
-0.03523966670036316,
0.012506700120866299,
0.030801421031355858,
0.060992591083049774,
0.009011185728013515,
-0.057472702115774155,
-0.058881714940071106,
0.03215552121400833,
0.0758354589343071,
0.0003711112367454916,
0.03036566451191902,
-0.062037669122219086,
0.09156358987092972,
0.012775898911058903,
0.005549725145101547,
-0.021147511899471283,
-0.06221717223525047,
0.04648890346288681,
-0.007964512333273888,
0.02187373675405979,
-0.07878316193819046,
-0.006122733931988478,
0.08978091180324554,
0.12080924212932587,
0.00845042709261179,
0.01278803963214159,
-0.055317576974630356,
-0.05608256906270981,
-0.002362141851335764,
-0.017406165599822998,
0.08743442595005035,
0.021327031776309013,
-0.014640536159276962,
-0.09611260145902634,
-0.04850795120000839,
-0.008070891723036766,
0.1012878492474556,
0.029214270412921906,
0.04799410328269005,
-0.04281703755259514,
0.0786716565489769,
-0.006428012158721685,
-0.043286509811878204,
-0.07581331580877304,
0.018090395256876945,
-0.0025852068793028593,
0.021730326116085052,
-0.006910126656293869,
0.009301367215812206,
0.05478382110595703,
0.004315946716815233,
-0.02314048632979393,
0.0020400730427354574,
-0.12034390866756439,
0.030444880947470665,
-0.0018168127862736583,
-0.02020786516368389,
0.03426164761185646,
-0.02683403342962265,
-0.03873944282531738,
-0.06805862486362457,
-0.033122409135103226,
0.05455015227198601,
0.0319235697388649,
-0.015031901188194752,
-0.058928344398736954,
0.025989066809415817,
-0.0828392431139946,
0.00921702105551958,
0.0884430855512619,
0.036578141152858734,
-0.00301881181076169,
0.0073426212184131145,
0.03315948694944382,
0.09499245882034302,
-0.0068580699153244495,
-0.005135613027960062,
0.03589210659265518,
-0.02009161375463009,
-0.06174735352396965,
-0.04789107292890549,
0.03412405773997307,
-0.0018537011928856373,
0.07110774517059326,
-0.015824085101485252,
-0.0005253563285805285,
3.6333361777228296e-34,
0.0441974513232708,
0.01319375354796648,
0.04611240327358246,
-0.011131889186799526,
0.009834391064941883,
0.0181280504912138,
0.054561905562877655,
-0.06911884993314743,
0.015208118595182896,
-0.020841332152485847,
0.07993857562541962,
0.06928953528404236,
0.07531589269638062,
-0.06825574487447739,
-0.03819594532251358,
0.061924438923597336,
-0.03955536708235741,
0.0502074770629406,
-0.13971376419067383,
-0.03951701521873474,
0.017351306974887848,
-0.0012208851985633373,
0.021096449345350266,
-0.04602579399943352,
0.03896953538060188,
0.019864948466420174,
-0.1107194721698761,
0.02887945994734764,
-0.02477186731994152,
0.020314844325184822,
-0.047759559005498886,
0.01360175758600235,
0.09704328328371048,
0.1360129415988922,
-0.022126557305455208,
0.04729598015546799,
-0.0037440243177115917,
-0.0009790818439796567,
0.03924889862537384,
0.04894775152206421,
0.07815901935100555,
-0.030585668981075287,
0.08223317563533783,
0.02815060317516327,
0.022114494815468788,
-0.060864511877298355,
-0.05541742965579033,
-0.018565626814961433,
-0.010273974388837814,
0.03924601897597313,
-0.012468899600207806,
0.0034923055209219456,
-0.012345588766038418,
-0.0761730745434761,
0.051979850977659225,
-0.018504304811358452,
-0.011808622628450394,
0.02750740759074688,
-0.00697955209761858,
0.013310862705111504,
0.01883617788553238,
-0.062380000948905945,
0.0013163213152438402,
0.05471178516745567,
0.013131039217114449,
0.01031490508466959,
-0.07321913540363312,
-0.030547134578227997,
-0.03404798358678818,
0.12803272902965546,
-0.09885579347610474,
0.10137394070625305,
-0.011025802232325077,
0.017074279487133026,
-0.010755630210042,
0.0027267769910395145,
-0.032845865935087204,
0.05443989112973213,
-0.10906688123941422,
0.05296848341822624,
-0.12980197370052338,
-0.004595976322889328,
-0.1467544585466385,
-0.000007512659522035392,
-0.02365192212164402,
0.04016970470547676,
0.0022766331676393747,
0.008280963636934757,
0.03412024676799774,
-0.0025238136295229197,
0.048818398267030716,
0.06691192090511322,
-0.026920076459646225,
0.011292709037661552,
0.02680460922420025,
-3.7922975900183064e-33,
-0.039777722209692,
0.005444999784231186,
0.056538574397563934,
0.036571793258190155,
-0.05058879777789116,
0.03497306630015373,
0.013149150647222996,
0.02046968601644039,
-0.0596340037882328,
0.002907025394961238,
-0.02653917670249939,
0.156704843044281,
-0.13800200819969177,
-0.08385494351387024,
-0.06667972356081009,
0.03473954647779465,
0.05998992919921875,
-0.045893728733062744,
0.018588505685329437,
-0.0006608078838326037,
-0.05112132430076599,
0.056875791400671005,
-0.009804433211684227,
-0.06978406757116318,
-0.10681387037038803,
-0.022498613223433495,
-0.009879672899842262,
-0.07403066009283066,
-0.01239491906017065,
-0.029956210404634476,
-0.031707823276519775,
0.06997977942228317,
-0.03192828968167305,
0.0017045882996171713,
0.05088042840361595,
0.007102552335709333,
-0.07220950722694397,
-0.09011800587177277,
0.027668438851833344,
0.06446342170238495,
-0.046219807118177414,
0.004509819205850363,
0.0038009770214557648,
-0.0006929466035217047,
-0.06946758925914764,
0.07127059996128082,
0.02852139249444008,
-0.014687730930745602,
0.04054601117968559,
0.00279203150421381,
-0.05561436340212822,
0.028092753142118454,
-0.0012310897000133991,
0.06074216216802597,
-0.029921086505055428,
0.02583308145403862,
-0.0753849446773529,
-0.037939611822366714,
-0.011916288174688816,
0.04692463576793671,
0.016358479857444763,
-0.021746739745140076,
-0.026680506765842438,
-0.05484054982662201,
-0.046315811574459076,
0.11669702082872391,
-0.07730299234390259,
-0.03686231002211571,
-0.06431755423545837,
0.11981881409883499,
-0.043896812945604324,
-0.12694132328033447,
-0.0256047360599041,
-0.021329058334231377,
-0.011423854157328606,
0.014629781246185303,
0.04506819695234299,
0.022685425356030464,
-0.04299930855631828,
0.04960726946592331,
0.011285263113677502,
0.09951107203960419,
-0.005418207962065935,
-0.04717671126127243,
0.058214347809553146,
0.09800110757350922,
-0.08875741809606552,
-0.0027807154692709446,
-0.047916609793901443,
-0.04233366996049881,
0.07257258892059326,
0.028952807188034058,
-0.01763918250799179,
-0.07575201988220215,
0.005079812835901976,
-2.569815293895772e-8,
-0.13118936121463776,
-0.07298573851585388,
0.017151661217212677,
-0.03707258775830269,
-0.040117401629686356,
0.05014494061470032,
-0.020963363349437714,
-0.0013737084809690714,
-0.011971722356975079,
0.01279383059591055,
-0.01475738175213337,
0.0017809664132073522,
-0.04719304293394089,
0.024930240586400032,
-0.027737963944673538,
0.01804506592452526,
-0.02071085385978222,
-0.03739561885595322,
-0.027123035863041878,
0.008559784851968288,
-0.04083522781729698,
-0.069910429418087,
0.07574140280485153,
-0.016737300902605057,
-0.012381669133901596,
0.07579931616783142,
-0.02727602608501911,
0.04251044616103172,
-0.01866268180310726,
0.011338917538523674,
0.07895804941654205,
-0.05755356699228287,
-0.009129057638347149,
0.03242947906255722,
-0.042480163276195526,
0.0439722053706646,
0.007516991812735796,
-0.03000243380665779,
-0.021408017724752426,
0.0638476237654686,
0.07831981778144836,
-0.0550413653254509,
-0.0021222801879048347,
0.020732317119836807,
-0.11834155768156052,
0.05528385937213898,
0.05327872186899185,
0.02775183878839016,
-0.024845996871590614,
-0.001565804472193122,
-0.013769191689789295,
-0.058651652187108994,
-0.0065569463185966015,
-0.05633643642067909,
-0.03067956119775772,
0.021366292610764503,
0.052565254271030426,
0.005589555483311415,
0.02421562187373638,
0.06987838447093964,
0.05928249657154083,
-0.0027242337819188833,
-0.03306274861097336,
0.00040597835322842
] |
PMID:25838188 | These initial results warrant validation in a larger clinical cohort. | [
-0.051878564059734344,
-0.0455380417406559,
0.02636123076081276,
0.03173043951392174,
0.01962883025407791,
-0.010043742135167122,
-0.10910478979349136,
0.09436792880296707,
-0.011724659241735935,
-0.029669323936104774,
0.01578722521662712,
0.023530444130301476,
-0.020828688517212868,
0.008904888294637203,
-0.06017330288887024,
-0.021076546981930733,
0.06886859983205795,
-0.03469925373792648,
-0.009049334563314915,
-0.03416967764496803,
-0.01732921600341797,
0.012150989845395088,
0.05407335236668587,
0.046918049454689026,
-0.02990352362394333,
-0.0239741038531065,
-0.079041987657547,
-0.0024091724772006273,
0.018128948286175728,
0.054270029067993164,
0.014186600223183632,
0.03015591762959957,
0.0350797064602375,
0.022576017305254936,
0.046570442616939545,
-0.012119335122406483,
-0.016481461003422737,
0.044419288635253906,
-0.05745694413781166,
0.028079744428396225,
0.05633467063307762,
-0.0938776507973671,
0.0013256107922643423,
0.035588447004556656,
0.015900935977697372,
-0.033471427857875824,
-0.05094330757856369,
0.07046128064393997,
-0.048990435898303986,
0.0755530446767807,
-0.07084687054157257,
0.008336460217833519,
0.007098795846104622,
0.08487728238105774,
0.02270425669848919,
-0.04956686869263649,
-0.077399343252182,
-0.07401121407747269,
-0.04171042516827583,
0.015577483922243118,
-0.07236448675394058,
-0.01811368204653263,
-0.037728529423475266,
0.041489969938993454,
0.013594391755759716,
0.05266522616147995,
0.020087098702788353,
-0.06859290599822998,
0.02086213231086731,
0.05009926110506058,
0.04137168079614639,
-0.017618194222450256,
-0.03163769096136093,
0.20225730538368225,
-0.07606081664562225,
0.027005676180124283,
-0.03666225075721741,
0.008714633993804455,
0.035580191761255264,
-0.057376690208911896,
-0.005609174724668264,
0.03731092810630798,
0.004903636872768402,
-0.006547942291945219,
0.05230110511183739,
0.0008374983444809914,
-0.04111302271485329,
-0.011588655412197113,
-0.10752595961093903,
-0.01361510343849659,
0.11169707030057907,
-0.01901714690029621,
-0.014315660111606121,
0.08679806441068649,
-0.06715038418769836,
-0.02026940882205963,
-0.03485779091715813,
-0.02632676623761654,
0.08360955864191055,
0.00830873940140009,
-0.05276373773813248,
-0.013349304907023907,
0.012806474231183529,
0.04237055033445358,
-0.02386121265590191,
-0.04364665597677231,
-0.006598078645765781,
-0.06784548610448837,
0.05014397203922272,
0.05251769721508026,
0.10459272563457489,
0.05401971563696861,
0.05061318725347519,
0.04559898003935814,
0.030494894832372665,
0.027900466695427895,
-0.0020960038527846336,
0.10714267194271088,
0.0633545070886612,
0.08569714426994324,
0.030054662376642227,
-0.0011570897186174989,
0.0413375198841095,
-0.06952734291553497,
0.008433756418526173,
-0.02474171482026577,
-0.07399146258831024,
-1.858420201793558e-33,
0.01425101887434721,
-0.004939595237374306,
0.0801331102848053,
0.05250447988510132,
-0.06337447464466095,
0.04819701611995697,
-0.1046018898487091,
-0.005857659503817558,
0.030982239171862602,
-0.034035053104162216,
-0.06651747971773148,
0.040462058037519455,
0.07627106457948685,
-0.006828106474131346,
-0.10959725081920624,
0.07166817039251328,
-0.041387464851140976,
0.11228287220001221,
-0.11136560142040253,
0.0639500841498375,
0.009562510997056961,
-0.08514869213104248,
0.03867622837424278,
0.004985171370208263,
-0.0892288014292717,
-0.0008897914085537195,
0.0005535473464988172,
0.06003497168421745,
-0.012856762856245041,
0.024182774126529694,
-0.02669668011367321,
-0.014709056355059147,
0.057620637118816376,
-0.04375097528100014,
-0.050969161093235016,
0.09847422689199448,
0.062474291771650314,
-0.04108670726418495,
0.07977234572172165,
0.0534515418112278,
-0.046414922922849655,
0.05331781506538391,
0.038108885288238525,
0.0030448243487626314,
0.0560484305024147,
-0.09604693204164505,
-0.07016536593437195,
-0.054167311638593674,
-0.045747898519039154,
0.016490334644913673,
-0.04700722545385361,
-0.012320340611040592,
-0.05408504977822304,
0.01165702659636736,
-0.06109026446938515,
0.06415432691574097,
-0.03892522677779198,
0.009821930900216103,
-0.004698973149061203,
0.01391279324889183,
0.13653331995010376,
-0.020086845383048058,
-0.11430899798870087,
-0.029629074037075043,
-0.03981391340494156,
0.05254683643579483,
-0.0022502460051327944,
-0.08846912533044815,
-0.03262792155146599,
0.03803061693906784,
0.0021645002998411655,
0.002768936101347208,
-0.006863803137093782,
0.05831494554877281,
0.031048540025949478,
-0.04087909683585167,
0.10476932674646378,
0.054736290127038956,
-0.01981264352798462,
-0.055468928068876266,
-0.01292745117098093,
-0.006529411766678095,
-0.06820349395275116,
0.08109395205974579,
0.03957453742623329,
-0.03472185507416725,
0.004315527621656656,
0.006213872227817774,
-0.07415821403265,
-0.04006996750831604,
0.0004778530274052173,
-0.0008387668640352786,
0.01509241946041584,
0.020439157262444496,
-0.04050416871905327,
-4.994128616264279e-34,
-0.04231562465429306,
0.0691932663321495,
-0.01146009936928749,
-0.0037500953767448664,
-0.0016253130743280053,
-0.005585432983934879,
0.03513093292713165,
-0.02277531288564205,
-0.008131410926580429,
-0.06690040975809097,
0.1112254410982132,
-0.0073388549499213696,
0.041692379862070084,
-0.06966875493526459,
-0.057665057480335236,
-0.02004682458937168,
-0.04826461896300316,
-0.04323110356926918,
0.003224425483494997,
0.022253284230828285,
0.14573346078395844,
-0.054821185767650604,
-0.04491455480456352,
0.06425334513187408,
-0.029824797064065933,
0.056575316935777664,
0.00022246449952945113,
-0.028759345412254333,
-0.03295082971453667,
-0.035212695598602295,
0.0020302797202020884,
0.026254398748278618,
-0.03299315273761749,
0.008859727531671524,
0.016063081100583076,
0.019108742475509644,
0.02996775694191456,
-0.03472387418150902,
-0.0030940198339521885,
0.02793888933956623,
-0.0067827426828444,
0.032532159239053726,
-0.06102045997977257,
-0.05288216099143028,
-0.05520772933959961,
-0.04832552373409271,
0.0844653844833374,
0.013736551627516747,
0.05682803690433502,
-0.059207476675510406,
-0.01731576770544052,
0.04600337892770767,
-0.0631689578294754,
0.04673665389418602,
0.0023528174497187138,
-0.09981189668178558,
-0.059633057564496994,
-0.017394065856933594,
-0.0878911241889,
0.025204533711075783,
-0.0741327777504921,
0.08303051441907883,
-0.10709381848573685,
0.05237862467765808,
0.02739204466342926,
-0.006850466597825289,
0.014779563061892986,
0.0020791005808860064,
0.03427988290786743,
-0.008840504102408886,
-0.059431981295347214,
-0.06822986155748367,
-0.05397837236523628,
-0.08065736293792725,
0.02094542607665062,
-0.03695928305387497,
-0.02025536634027958,
-0.0570947639644146,
-0.05523894354701042,
0.025836866348981857,
-0.06955976039171219,
-0.06721948087215424,
0.004651423078030348,
0.07743613421916962,
-0.04891860485076904,
0.028966771438717842,
0.0814438909292221,
-0.09528923034667969,
-0.04010559991002083,
0.11487888544797897,
-0.02408437244594097,
0.02895602025091648,
-0.025688590481877327,
-0.05265491083264351,
-0.09317594021558762,
-2.2239730057549423e-8,
-0.0030163549818098545,
0.02900169976055622,
0.01447187177836895,
0.04380792751908302,
0.022348199039697647,
-0.014509482309222221,
-0.11983205378055573,
0.01931757666170597,
0.004801264498382807,
-0.0369843915104866,
0.061753157526254654,
0.032630305737257004,
-0.0076541593298316,
-0.040667809545993805,
0.028548097237944603,
0.05059824511408806,
0.013340429402887821,
0.06960292160511017,
-0.030865008011460304,
0.002455771202221513,
-0.05110207200050354,
0.03785379230976105,
0.041131533682346344,
-0.07981251180171967,
-0.014503265731036663,
0.04038425534963608,
-0.017980799078941345,
0.1071559339761734,
-0.07279712706804276,
0.0005588032072409987,
0.019453376531600952,
0.011912621557712555,
0.060928959399461746,
-0.03618178144097328,
0.04258320853114128,
-0.021709365770220757,
0.0038597623351961374,
0.04570981487631798,
0.04800000786781311,
0.003053590189665556,
0.018572071567177773,
0.004472768399864435,
0.004295861814171076,
0.051257986575365067,
0.04319598525762558,
-0.05681765452027321,
0.008762023411691189,
0.040210600942373276,
-0.0017104417784139514,
-0.08587559312582016,
0.00538788503035903,
-0.02807122841477394,
-0.007551677990704775,
0.015117352828383446,
-0.027414601296186447,
0.11627268046140671,
-0.01605682261288166,
-0.0031788547057658434,
-0.0239295344799757,
-0.039223868399858475,
0.0855465978384018,
-0.009381613694131374,
0.07586365193128586,
-0.01015645544975996
] |
PMID:25699604 | Inhibitors of histone deacetylases (HDACi) hold considerable therapeutic promise as clinical anticancer therapies. | [
-0.03845349699258804,
0.0431978739798069,
-0.04200800880789757,
-0.0380830243229866,
-0.08758342266082764,
-0.01174873486161232,
-0.02677629515528679,
-0.046196602284908295,
-0.09735359996557236,
-0.00027028904878534377,
-0.0414588525891304,
0.01369335688650608,
0.0012247466947883368,
0.015723148360848427,
-0.006381675135344267,
0.06233659386634827,
-0.02776344120502472,
-0.03737672418355942,
-0.06722120940685272,
-0.015849817544221878,
-0.051947128027677536,
0.03318535536527634,
0.056551843881607056,
0.04713795706629753,
-0.04358978942036629,
-0.056377116590738297,
0.013256249949336052,
0.06794239580631256,
-0.07370297610759735,
-0.052569594234228134,
0.022466640919446945,
-0.06357817351818085,
0.04261943697929382,
-0.015352149493992329,
0.05452284961938858,
0.002475087996572256,
-0.07796835154294968,
0.04609496891498566,
-0.008671470917761326,
-0.0349869579076767,
0.0791327953338623,
-0.03973295912146568,
-0.08757545053958893,
0.058360710740089417,
-0.005075807683169842,
-0.13572943210601807,
-0.14485713839530945,
-0.07611954212188721,
0.059279631823301315,
0.0984068438410759,
-0.028061354532837868,
0.08207899332046509,
0.01536636520177126,
-0.024901235476136208,
0.021066978573799133,
0.016863202676177025,
0.017675485461950302,
0.014056962914764881,
0.018678419291973114,
-0.06741004437208176,
0.04003926366567612,
-0.10585036128759384,
-0.02284138649702072,
0.0123714255169034,
0.025971436873078346,
-0.02748548611998558,
0.09329549223184586,
-0.07703074812889099,
0.034999918192625046,
0.051881011575460434,
-0.015616319142282009,
-0.048203542828559875,
0.0004821493348572403,
0.09357307106256485,
0.07152152061462402,
-0.13928043842315674,
-0.0038034103345125914,
0.005979673936963081,
-0.031472209841012955,
-0.051165979355573654,
0.052445393055677414,
-0.036885328590869904,
0.11978118866682053,
0.08495964109897614,
-0.0045937346294522285,
0.04895704612135887,
-0.02519058994948864,
-0.047916047275066376,
0.045203614979982376,
0.03646368905901909,
0.037140656262636185,
-0.007976840250194073,
-0.023771850392222404,
0.010203162208199501,
0.0066180420108139515,
-0.036739811301231384,
0.020806673914194107,
0.004529421683400869,
-0.08206281065940857,
0.03454560041427612,
0.06319788098335266,
-0.041490983217954636,
-0.12985458970069885,
-0.0812373235821724,
-0.004157263785600662,
0.03843219205737114,
0.023647690191864967,
-0.03981325775384903,
-0.029735486954450607,
0.013930166140198708,
0.05593488737940788,
-0.03618069738149643,
0.012769082561135292,
0.06476479023694992,
-0.046535611152648926,
0.10154443979263306,
0.02744082175195217,
0.030085258185863495,
0.05611613392829895,
-0.08360607922077179,
0.016749057918787003,
0.000020162486180197448,
0.054481275379657745,
0.00849253498017788,
-0.06536280363798141,
-0.025165485218167305,
-0.09946682304143906,
3.3077269976099407e-34,
-0.012474322691559792,
0.025444883853197098,
-0.04573492333292961,
0.018222974613308907,
0.016147347167134285,
-0.07294001430273056,
-0.07239440828561783,
0.047281187027692795,
-0.01655028760433197,
-0.09513934701681137,
0.0503450445830822,
0.07652293145656586,
0.016799727454781532,
0.06863914430141449,
-0.029860924929380417,
-0.05319603905081749,
0.07358434051275253,
0.044025637209415436,
-0.025649070739746094,
-0.07608523964881897,
-0.04940744861960411,
0.029351698234677315,
-0.002580537460744381,
-0.010107822716236115,
0.00486809853464365,
0.037575751543045044,
-0.013343121856451035,
0.1084284707903862,
0.07893241196870804,
0.011140162125229836,
-0.005615674424916506,
0.019021617248654366,
0.036501556634902954,
0.029065413400530815,
0.04137127473950386,
0.04550177603960037,
-0.0114424554631114,
0.0009732231264933944,
0.10350510478019714,
0.0606558732688427,
0.0044213938526809216,
-0.002405912382528186,
-0.053141672164201736,
-0.08708248287439346,
-0.0007128126453608274,
-0.048510171473026276,
-0.057456646114587784,
0.0028235637582838535,
-0.08375893533229828,
0.004863675683736801,
0.014550887979567051,
-0.045296017080545425,
0.05176227539777756,
0.06009378656744957,
0.005038498435169458,
0.0005659717135131359,
-0.012458356097340584,
-0.005366803612560034,
0.11983364820480347,
0.02339419163763523,
-0.012760707177221775,
0.003403738606721163,
0.021812956780195236,
0.06286070495843887,
-0.03254120051860809,
-0.012314178980886936,
-0.06891469657421112,
-0.016379302367568016,
-0.08253226429224014,
-0.03660948574542999,
0.011734189465641975,
0.06982406973838806,
0.08899106830358505,
0.007891196757555008,
0.030946774408221245,
-0.042864520102739334,
-0.059859439730644226,
0.04036024957895279,
-0.10148611664772034,
0.13894544541835785,
0.0920509546995163,
-0.04089462757110596,
-0.08798355609178543,
0.0117441201582551,
-0.02938239276409149,
-0.018735045567154884,
0.038123369216918945,
-0.07649089395999908,
-0.008860861882567406,
0.005885498598217964,
-0.03854699060320854,
-0.03499934822320938,
0.035902656614780426,
-0.020957307890057564,
0.05708153173327446,
-3.6532957503755555e-33,
0.0967458114027977,
0.02180342935025692,
0.060851480811834335,
0.007043385412544012,
0.015104326419532299,
0.025717061012983322,
0.09065427631139755,
-0.02858959697186947,
0.0848773717880249,
0.008232093416154385,
0.10109565407037735,
-0.012441052123904228,
0.0021059869322925806,
-0.09279140084981918,
0.0012315274216234684,
0.0592823401093483,
-0.006132727954536676,
0.012513692490756512,
-0.09179440140724182,
-0.02241981402039528,
0.007089540828019381,
0.07363101094961166,
-0.04770501330494881,
0.05302607640624046,
-0.01062897127121687,
-0.05368596315383911,
-0.04122527688741684,
0.04968605190515518,
0.009083777666091919,
0.015538536012172699,
-0.04334620013833046,
0.002506238641217351,
-0.06576459854841232,
-0.047169215977191925,
0.013113762252032757,
0.05506480112671852,
-0.01109990943223238,
-0.03182028606534004,
-0.0807722881436348,
-0.008122878149151802,
-0.054223477840423584,
-0.02001609466969967,
-0.023782650008797646,
0.021520119160413742,
0.016078529879450798,
0.11254262179136276,
-0.0010333346435800195,
0.10218658298254013,
-0.04086162522435188,
-0.0006435885443352163,
0.08501757681369781,
0.008978701196610928,
-0.0020945146679878235,
0.01201994065195322,
0.022090919315814972,
-0.0020546969026327133,
0.05022851377725601,
-0.0015865466557443142,
-0.042521603405475616,
0.031186211854219437,
-0.05269232392311096,
0.05871329829096794,
0.029091501608490944,
0.06970187276601791,
-0.05934504419565201,
0.0859333947300911,
-0.051048628985881805,
-0.01361334603279829,
0.02793010324239731,
0.019521471112966537,
-0.025984007865190506,
-0.006217378191649914,
-0.012264134362339973,
0.05108293518424034,
-0.051321592181921005,
0.07501082122325897,
-0.03340109810233116,
-0.04994859918951988,
-0.017222197726368904,
-0.02984112687408924,
0.0038705081678926945,
-0.02531752549111843,
0.021289078518748283,
-0.0022615366615355015,
-0.047872330993413925,
-0.03868814557790756,
-0.029563868418335915,
-0.05151009187102318,
-0.09950532019138336,
0.05487867072224617,
0.04345297813415527,
-0.0744592621922493,
-0.045959290117025375,
0.07099752873182297,
0.007937995716929436,
-2.4768811002218172e-8,
0.09456156939268112,
-0.10213954001665115,
0.018832385540008545,
-0.08733723312616348,
-0.028708945959806442,
-0.013210504315793514,
0.016460716724395752,
0.04294198378920555,
0.062337473034858704,
-0.03410317376255989,
0.007333762943744659,
0.03153368458151817,
-0.007212708238512278,
-0.01546210702508688,
-0.09954234212636948,
-0.05361499637365341,
0.05519456788897514,
0.07251733541488647,
-0.014481422491371632,
-0.06584898382425308,
0.005230268929153681,
0.0035627014003694057,
-0.010050227865576744,
-0.005872073583304882,
-0.010999318212270737,
0.003054714063182473,
-0.03307708725333214,
-0.0043757278472185135,
-0.035798605531454086,
-0.09076841175556183,
0.03005829267203808,
-0.024282602593302727,
0.048791442066431046,
0.00029803309007547796,
0.043722428381443024,
0.011745460331439972,
0.04342832788825035,
-0.02659728191792965,
0.03128122165799141,
0.024307839572429657,
0.046591948717832565,
0.04741529002785683,
-0.06199778616428375,
-0.01302629616111517,
-0.07816839963197708,
-0.06188836693763733,
-0.0005748457624576986,
0.0074588158167898655,
-0.02054399996995926,
-0.02839737944304943,
-0.013254621997475624,
0.08643977344036102,
0.016610171645879745,
-0.08660603314638138,
-0.038515444844961166,
0.04632090777158737,
-0.0414566844701767,
-0.0068029253743588924,
-0.0634961947798729,
0.008950446732342243,
0.08520612865686417,
-0.029337741434574127,
0.06042086333036423,
-0.06913509219884872
] |
Subsets and Splits