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Using O=N[O-], Cc1ccc([N+](=O)[O-])c(C)c1N to produce Cc1ccc([N+](=O)[O-])c(C)c1O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O"], "agent": ["O=S(=O)(O)O", "[Na+]"]}
|
Using O=CO, CCCNC1CCc2c(cccc2NC(C)=O)C1 to produce CCCN(C)C1CCc2c(cccc2NC(C)=O)C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "ClCCl"], "agent": ["C=O", "N"]}
|
Using CCCCn1c(N)c(NC(=O)Cc2ccc(S(=O)(=O)Nc3ccccn3)cc2)c(=O)n(Cc2ccccc2F)c1=O to produce CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(S(=O)(=O)Nc4ccccn4)cc3)nc21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["[Na+]", "[OH-]"]}
|
Using O=C1NC(=O)c2ccccc21, Cc1ncccc1-c1nc2c(Cl)cccc2cc1C(C)Cl to produce Cc1ncccc1-c1nc2c(Cl)cccc2cc1C(C)N1C(=O)c2ccccc2C1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["[K]", "Cl"]}
|
Using CC(=O)c1ccccn1 to produce O=C(CBr)c1ccccn1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1", "ClC(Cl)Cl"], "agent": ["c1cc[nH+]cc1"]}
|
Using O=C1C(C2=NS(=O)(=O)c3cc(Br)cnc3N2)=C(O)C2C3CCC(C3)C2N1Cc1ccc(F)cc1 to produce O=C1C(C2=NS(=O)(=O)c3cccnc3N2)=C(O)[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2N1Cc1ccc(F)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O", "CO"], "agent": ["O=C[O-]", "[NH4+]", "[Pd]"]}
|
Using O=N[O-], Nc1ccc2c(=O)[nH]cnc2c1 to produce O=c1[nH]cnc2cc(O)ccc12, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O"], "agent": ["O=S(=O)(O)O", "[Na+]"]}
|
Using COc1ccc(C(CO)NC(=O)OC(C)(C)C)cc1 to produce COc1ccc(C(N)CO)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["[Na+]", "Cl", "[OH-]"]}
|
Using COC(=O)C(OC1C=CCCC1)c1ccc(S(C)(=O)=O)c(Cl)c1 to produce CS(=O)(=O)c1ccc(C(OC2C=CCCC2)C(=O)O)cc1Cl, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CCO"], "agent": ["[K+]", "[OH-]"]}
|
Using CN1C2CCC1C1CCC2N1Cc1ccccc1 to produce CN1C2CCC1C1CCC2N1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[H][H]", "[Pd]"]}
|
Using CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(CCl)CS[C@H]23)cs1, O=C(OO)c1cccc(Cl)c1 to produce CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(CCl)CS(=O)[C@H]23)cs1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["[Na+]", "O=S([O-])([O-])=S"]}
|
Using C=CCc1c(O)c(C(C)=O)cc2c1OCc1cc(OC)ccc1C2=O to produce COc1ccc2c(c1)COc1c(cc(C(C)=O)c3c1CC(C)O3)C2=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3"]}
|
Using CC(C)(C)OC(=O)NCCN(CCC(c1ccccc1)c1ccccc1)C(=O)c1ccccc1 to produce NCCN(CCC(c1ccccc1)c1ccccc1)C(=O)c1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCCCCC", "CCOC(C)=O"], "agent": ["Cl"]}
|
Using COc1cc(CC(=O)Cl)ccc1OCc1ccccc1, NCC1(O)CCc2ccccc21 to produce COc1cc(CC(=O)NCC2(O)CCc3ccccc32)ccc1OCc1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["[Na+]", "O=C([O-])O"]}
|
Using Oc1ccc(N=Nc2ccccc2)c(F)c1F to produce Nc1ccc(O)c(F)c1F, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["C", "[H][H]"]}
|
Using CC1(C)OB(C2=CCN(C(=O)N3CCOc4ccccc43)C2)OC1(C)C, Fc1ccc(Br)c(C(F)(F)F)c1 to produce O=C(N1CC=C(c2ccc(F)cc2C(F)(F)F)C1)N1CCOc2ccccc21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "COCCOC"], "agent": ["O=C([O-])[O-]", "[Na+]"]}
|
Using Cc1c(NC(=O)c2cccc(OCCNC(=O)OC(C)(C)C)c2)c2ccccn2c1C(=O)c1ccc(NC(=O)C(F)(F)F)c(C(=O)OCc2ccccc2)c1 to produce Cc1c(NC(=O)c2cccc(OCCN)c2)c2ccccn2c1C(=O)c1ccc(NC(=O)C(F)(F)F)c(C(=O)OCc2ccccc2)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O=C(O)C(F)(F)F", "ClCCl"], "agent": ["[Na+]", "O=C([O-])O"]}
|
Using CC(C)(C)[Si](C)(C)Cl, C[C@H](c1ccccc1)N1C[C@@](CO)(C(=O)OC(C)(C)C)CC1=O to produce C[C@H](c1ccccc1)N1C[C@@](CO[Si](C)(C)C(C)(C)C)(C(=O)OC(C)(C)C)CC1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["[Cl-]", "[NH4+]", "c1c[nH]cn1"]}
|
Using COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2 to produce O=C(N1CCc2ccc(O)cc2CC1)C(F)(F)F, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["BrB(Br)Br"]}
|
Using COC(=O)[C@H]1CC(=O)C[C@H]1C(=O)OC to produce COC(=O)C1=CC(=O)CC1C(=O)OC, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O", "C1CCOC1"], "agent": ["O=C([O-])[O-]", "[Ca+2]"]}
|
Using O=C(Cl)CN1C(=O)c2ccccc2C1=O, O=C1[C@H]2CCC[C@H]2Nc2ccccc2N1Cc1ccc(OCc2ccccc2)cc1 to produce O=C1c2ccccc2C(=O)N1CC(=O)N1c2ccccc2N(Cc2ccc(OCc3ccccc3)cc2)C(=O)[C@H]2CCC[C@H]21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCCl"], "agent": ["[Na+]", "O=C([O-])O"]}
|
Using CCOC(=O)c1cnn2c1c(OCC)nc1ccccc12 to produce CCOc1nc2ccccc2n2ncc(C(=O)O)c12, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[Na+]", "[OH-]"]}
|
Using CC(C)(C)O, CC(=O)[C@@H]1C[C@H](C(=O)O)C1(C)C to produce CC(=O)[C@@H]1C[C@H](C(=O)OC(C)(C)C)C1(C)C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O", "C1CCOC1"], "agent": ["C(=NC1CCCCC1)=NC1CCCCC1"]}
|
Using O=C1CCN(Cc2ccccc2)C1, CC(C)(C)NS(=O)(=O)c1ccccc1 to produce CC(C)(C)NS(=O)(=O)c1ccccc1C1(O)CCN(Cc2ccccc2)C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOCC", "CCCCC"], "agent": ["[Li]C(C)(C)C"]}
|
Using CCOC(=O)C=CC1(NC(=O)OC(C)(C)C)CCOCC1 to produce CCOC(=O)CCC1(NC(=O)OC(C)(C)C)CCOCC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O", "CO"], "agent": ["[H][H]", "[C]", "[Pd]"]}
|
Using CN1CCNCC1, O=C1CCC(C(=O)NCc2nccnc2Cl)CC1 to produce CN1CCN([C@H]2CC[C@H](C(=O)NCc3nccnc3Cl)CC2)CC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC(=O)O", "ClCCl"], "agent": ["[BH3-]C#N", "[Na+]", "O=C([O-])O"]}
|
Using CC(C)(C)OC(=O)c1cccc([N+](=O)[O-])c1 to produce CC(C)(C)OC(=O)c1cccc(N)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[Pd]"]}
|
Using CC(C)(C)OC(=O)Nc1ncc(Br)s1, C#C[Si](C)(C)C to produce CC(C)(C)OC(=O)Nc1ncc(C#C[Si](C)(C)C)s1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CCN(CC)CC"], "agent": ["[Cu]I"]}
|
Using CC(=O)c1cccc2ccccc12, COC(=O)c1ccccc1 to produce O=C(CC(=O)c1cccc2ccccc12)c1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOCC"], "agent": ["[Na+]", "Cl", "[NH2-]"]}
|
Using CCOC(=O)c1cc(C(=O)OCC)[nH]n1, [O-]Cl to produce CCOC(=O)c1n[nH]c(C(=O)OCC)c1Cl, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC(=O)O"], "agent": ["[Na+]"]}
|
Using N[C@@H]1CCCC[C@H]1O, O=C(O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1 to produce O=C(N[C@@H]1CCCC[C@H]1O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O", "CCN(C(C)C)C(C)C"], "agent": ["CN(C)C(On1nnc2ccccc21)=[N+](C)C", "Cl", "F[B-](F)(F)F"]}
|
Using C=CC(=O)Cl, Cc1cccc(C(=O)NC(C)C)c1N to produce C=CC(=O)Nc1c(C)cccc1C(=O)NC(C)C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl", "CCN(CC)CC"], "agent": ["Cl", "CN(C)c1ccccn1"]}
|
Using CCO, CNc1c(OCc2ccccc2)cc(Br)cc1[N+](=O)[O-] to produce Cn1cnc2cc(Br)cc(OCc3ccccc3)c21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O=CO"], "agent": ["[Fe]"]}
|
Using COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c3c(oc12)CN(C(=O)OC(C)(C)C)CC3 to produce COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c3c(oc12)CNCC3, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O"], "agent": ["Cl"]}
|
Using Oc1cc(C(F)(F)F)ccc1Cl, CC(C)(C)[Si](C)(C)OCC1=CC=C(CO)SS1 to produce CC(C)(C)[Si](C)(C)OCC1=CC=C(COc2cc(C(F)(F)F)ccc2Cl)SS1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["c1ccc(P(c2ccccc2)c2ccccc2)cc1", "CCOC(=O)/N=N/C(=O)OCC"]}
|
Using COC(=O)CCc1ccccc1O, OCCNC(c1ccccc1)(c1ccccc1)c1ccccc1 to produce COC(=O)CCc1ccccc1OCCNC(c1ccccc1)(c1ccccc1)c1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["c1ccc(P(c2ccccc2)c2ccccc2)cc1", "CCOC(=O)N=NC(=O)OCC"]}
|
Using COc1ccc2c(c1)CC(C)C(Br)=C2c1ccc(Cl)cc1 to produce COc1ccc2c(-c3ccc(Cl)cc3)c(Br)c(C)cc2c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["Cc1ccccc1"], "agent": ["N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O"]}
|
Using CCCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)O)ccc1OC, CO to produce CCCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1OC, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1COCCO1"], "agent": ["Cl"]}
|
Using O=S(Cl)Cl, O=S([O-])CCC=C(F)F to produce O=S(Cl)CCC=C(F)F, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCCCCC"], "agent": ["[Na+]"]}
|
Using OCc1ccccc1, CC(C)C(Cl)OC(=O)NCC1(CC(=O)O)CCCCC1 to produce CC(C)C(Cl)OC(=O)NCC1(CC(=O)OCc2ccccc2)CCCCC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["CN(C)c1ccncc1", "C(=NC1CCCCC1)=NC1CCCCC1"]}
|
Using O=C(O)C(SCc1ccccc1)C(=O)O, CC(=O)c1c(C)cccc1C to produce Cc1cccc(C)c1-c1cc(O)c(SCc2ccccc2)c(=O)o1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["C[Si](C)(C)[N-][Si](C)(C)C", "[Li+]", "C[Si](C)(C)Cl"]}
|
Using CC(=N)N, CCOC(=O)CC(=O)c1cc(Cl)ccc1OC to produce COc1ccc(Cl)cc1-c1cc(=O)[nH]c(C)n1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["O=C([O-])[O-]", "[K+]", "Cl"]}
|
Using CC(C)(C)OC(=O)C[C@@H](CS(=O)(=O)c1ccccc1)NC(=O)OCc1ccccc1 to produce CC(C)(C)OC(=O)C[C@H](N)CS(=O)(=O)c1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC(=O)O"], "agent": ["[H][H]", "[Pd]"]}
|
Using ClCc1ccnc(Cl)c1, O=C(COCc1ccccc1)N1CCNCC1 to produce O=C(COCc1ccccc1)N1CCN(Cc2ccnc(Cl)c2)CC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using O=C(O)C(=O)Nc1cccccc1=O, CCCCCBr to produce CCCCCOC(=O)C(=O)Nc1cccccc1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CS(C)=O"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using BrCc1ccccc1, CC(C)(C)OC(=O)N1CC(=O)C[C@H]1C(=O)O to produce CC(C)(C)OC(=O)N1CC(=O)C[C@H]1C(=O)OCc1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O", "CN(C)C=O"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using CCOC(=O)c1cn(-c2cccc(-c3cnc(OC)nc3OC)c2)cn1 to produce COc1ncc(-c2cccc(-n3cnc(C(=O)O)c3)c2)c(OC)n1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[K+]", "[OH-]"]}
|
Using COC(=O)c1ccc([N+](=O)[O-])cc1NC(C)=O to produce COC(=O)c1ccc(N)cc1NC(C)=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["[Pd]"]}
|
Using CCOP(=O)(CC(=O)OC(C)(C)C)OCC, N#Cc1ccc(C=O)cc1 to produce CC(C)(C)OC(=O)/C=C/c1ccc(C#N)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1", "COC(C)(C)C"], "agent": ["[Cl-]", "[NH4+]"]}
|
Using CI, CN(CC(=O)N(C)c1ccc(CO)cc1)C(=O)OCc1ccccc1 to produce COCc1ccc(N(C)C(=O)CN(C)C(=O)OCc2ccccc2)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["[Na+]", "[H-]"]}
|
Using COc1ccc2ccc(OC)c(C=O)c2c1 to produce COc1ccc2ccc(O)c(C=O)c2c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["[Na+]", "O=C([O-])O"]}
|
Using CC(C)(C)OC(=O)NC1Cc2ccc([N+](=O)[O-])cc2C1 to produce CC(C)(C)OC(=O)NC1Cc2ccc(N)cc2C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[Pd]"]}
|
Using CI, O=C1COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)c([N+](=O)[O-])c2N1 to produce CN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)c([N+](=O)[O-])c21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["[Na+]", "[H-]"]}
|
Using OCCNc1ncccn1, O=Cc1ccc(F)cc1 to produce O=Cc1ccc(OCCNc2ncccn2)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CN(C)C=O"], "agent": ["[Na+]", "[H-]"]}
|
Using CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(Cc3cccc(CC(=O)OC)c3)C(=O)CC(=O)OC(C)(C)C)c2n1 to produce CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(Cc3cccc(CC(=O)OC)c3)C(=O)CC(=O)OC)c2n1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1COCCO1", "CO"], "agent": ["Cl"]}
|
Using Nc1nc(Cl)cc(Cl)n1, CC(C)(N)Cc1ccccc1 to produce CC(C)(Cc1ccccc1)Nc1cc(Cl)nc(N)n1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC#N", "CCN(C(C)C)C(C)C"], "agent": ["Cl"]}
|
Using CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CC[C@H](CNC(=O)OC(C)(C)C)CC1 to produce CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1CC[C@H](CN)CC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1COCCO1"], "agent": ["Cl"]}
|
Using COB(OC)OC, COc1ccc2c(ccn2[Si](C(C)C)(C(C)C)C(C)C)n1 to produce COB(O)c1cc2c(ccn2[Si](C(C)C)(C(C)C)C(C)C)nc1OC, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["[Li]CCCC"]}
|
Using O=C(O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(OC(F)F)c2c1=O to produce O=C([O-])c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(OC(F)F)c2c1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O"], "agent": ["[Na+]", "[OH-]"]}
|
Using CCOC(=O)CC1(C(=O)OCC)Cc2cc(F)ccc2C1=O to produce O=C(O)CC1Cc2cc(F)ccc2C1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC(=O)O"], "agent": ["Cl"]}
|
Using O=[N+]([O-])c1cc(C(F)(F)F)ccc1Cl to produce O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Cl, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "O=[N+]([O-])O"], "agent": ["O=S(=O)(O)O"]}
|
Using CCOC(=O)/C(=C/CC1CCCCC1)c1ccc(S(C)(=O)=O)cc1 to produce CS(=O)(=O)c1ccc(/C(=C\CC2CCCCC2)CO)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["Cc1ccccc1"], "agent": ["CC(C)C[AlH]CC(C)C"]}
|
Using COCOC, COc1cccc2c1OC(CO)C2=O to produce COCOCC1Oc2c(OC)cccc2C1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3", "[Na+]", "O=C([O-])O"]}
|
Using CCCC(O)(CCC)c1c2c(nn1C)N(c1c(C)cc(C)cc1Cl)CCC2 to produce CCC=C(CCC)c1c2c(nn1C)N(c1c(C)cc(C)cc1Cl)CCC2, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "Cc1ccccc1"], "agent": ["Cc1ccc(S(=O)(=O)O)cc1"]}
|
Using CC(=O)OC[C@@H](C)n1ccc2c([N+](=O)[O-])c(C)ccc2c1=O to produce CC(=O)OC[C@@H](C)n1ccc2c(N)c(C)ccc2c1=O, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CCO"], "agent": ["[Cl-]", "[Fe]", "[NH4+]"]}
|
Using CCOC(=O)CBr, C[C@@H]1CCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1 to produce CCOC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CCC[C@H]1C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["C[Si](C)(C)[N-][Si](C)(C)C", "[Li+]"]}
|
Using CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(C(F)(F)F)c3)C2=O)o1 to produce CC1(C)CN(Cc2ccc(C(=O)O)o2)C(=O)C1Oc1ccc(C#N)c(C(F)(F)F)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["[Na+]", "Cl", "[OH-]"]}
|
Using Cc1cc(F)c(N)cc1-c1cc2cnc(Cl)cc2nc1C, C=C(C)OC(=O)Cl to produce C=C(C)OC(=O)Nc1cc(-c2cc3cnc(Cl)cc3nc2C)c(C)cc1F, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O"], "agent": ["[Na+]", "O=C([O-])O"]}
|
Using C[Si](C)(C)Cl, Cc1cc(Br)cc(C)c1N to produce Cc1cc(Br)cc(C)c1N([Si](C)(C)C)[Si](C)(C)C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "C1CCOC1"], "agent": ["[Li]CCCC"]}
|
Using CC(=O)O[C@@H]1O[C@H](COCc2ccccc2)[C@H](N=[N+]=[N-])[C@H](OCc2ccccc2)[C@H]1OC(C)=O to produce [N-]=[N+]=N[C@@H]1[C@H](OCc2ccccc2)[C@@H](O)C(O)O[C@@H]1COCc1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CO"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using NCC(=O)O, CCOC(=O)c1ncc2nc(-c3cccc(OC)c3)sc2c1O to produce COc1cccc(-c2nc3cnc(C(=O)NCC(=O)O)c(O)c3s2)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["C[O-]", "[Na+]"]}
|
Using COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1c1ccccc1 to produce CC(C)(C)OC(=O)N1CC[C@H](c2ccccc2)[C@@H](C(=O)O)C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1", "CO"], "agent": ["[Na+]", "[OH-]"]}
|
Using COc1ccc(CCl)cc1, Cn1c(Cl)ncc(O)c1=O to produce COc1ccc(COC2=CN(C)C(Cl)N=C2)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["O=C([O-])[O-]", "[Cs+]"]}
|
Using CC(C)(C)OC(=O)n1nc(-c2cc3cc(OCCBr)ccc3n2C(=O)OC(C)(C)C)c2cc(OCc3ccccc3)ccc21, C1COCCN1 to produce CC(C)(C)OC(=O)n1nc(-c2cc3cc(OCCN4CCOCC4)ccc3n2C(=O)OC(C)(C)C)c2cc(OCc3ccccc3)ccc21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC#N", "ClCCl"], "agent": ["O=C([O-])[O-]", "[I-]", "[K+]"]}
|
Using CCOC(=O)C(CCCCCC1CCCCCC1)C(=O)O to produce C=C(CCCCCC1CCCCCC1)C(=O)OCC, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["c1ccncc1", "C1CCNCC1"], "agent": ["C=O"]}
|
Using [BH3-]C#N, c1cc2c(s1)CCNC2 to produce CN1CCc2sccc2C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl"], "agent": ["[Na+]", "Cl", "C=O"]}
|
Using O=C(c1ccccc1)C(F)(F)Cl, CCC[C@H](c1ccc(C(=O)NCCC(=O)OCC)cc1)C(c1ccc(Cl)cc1)c1ccc2cc(O)ccc2c1 to produce CCC[C@H](c1ccc(C(=O)NCCC(=O)O)cc1)C(c1ccc(Cl)cc1)c1ccc2cc(OC(F)F)ccc2c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CC#N"], "agent": ["[K+]", "[OH-]"]}
|
Using CC(=O)NCCc1coc2ccc(C=O)cc12, O=[Mn](=O)(=O)[O-] to produce CC(=O)NCCc1coc2ccc(C(=O)O)cc12, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CC(C)=O"], "agent": ["[K+]"]}
|
Using C=C(C)B1OC(C)(C)C(C)(C)O1, CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3c2c(NC(=O)C2CC2)cn3C(=O)OC(C)(C)C)C1 to produce C=C(C)c1cnc2[nH]cc(NC(=O)C3CC3)c2c1N1CCC[C@@H](NC(=O)OC(C)(C)C)C1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1COCCO1"], "agent": ["O=C([O-])[O-]", "[Na+]", "c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1"]}
|
Using [C-]#N, BrCc1nc(-c2ccccc2)nn1-c1cccnc1 to produce N#CCc1nc(-c2ccccc2)nn1-c1cccnc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CS(C)=O"], "agent": ["[K+]"]}
|
Using CC(=O)Oc1cccc2c1OCCN2CCOC(c1ccccc1)c1ccccc1 to produce Oc1cccc2c1OCCN2CCOC(c1ccccc1)c1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1", "CO"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using CC(C)[Mg]Cl, COc1ccccc1/N=C/c1ccccc1 to produce COc1ccccc1NC(c1ccccc1)C(C)C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["[Cl-]", "[NH4+]"]}
|
Using CC(=O)Nc1c(C)cc([N+](=O)[O-])c(C)c1[N+](=O)[O-] to produce Cc1cc([N+](=O)[O-])c(C)c([N+](=O)[O-])c1N, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CCO"], "agent": ["O=S(=O)(O)O"]}
|
Using C1CCNC1, Nc1ncnn2c(CCCCBr)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 to produce Nc1ncnn2c(CCCCN3CCCC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O", "CCN(CC)CC"], "agent": ["[Na+]", "[I-]"]}
|
Using COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCCN1CCCC1 to produce COc1cc2c(=O)[nH]cnc2cc1OCCN1CCCC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CO"], "agent": ["N"]}
|
Using CC(=O)OC1CCC2CN(Cc3ccccc3)CC2C1=O, COc1ccccc1[Mg]Br to produce COc1ccccc1C1(O)C(O)CCC2CN(Cc3ccccc3)CC21, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOCC", "C1CCOC1"], "agent": ["[Cl-]", "[NH4+]"]}
|
Using O=c1ccc2ccccc2o1 to produce O=C1CCc2ccccc2O1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O"], "agent": ["O=[Pt]"]}
|
Using O=C(O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1, Cc1cc(N)n(C)n1 to produce Cc1cc(NC(=O)c2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)n(C)n1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O", "CCN(CC)CC"], "agent": ["CCN=C=NCCCN(C)C", "On1nnc2ccccc21", "Cl"]}
|
Using CS(=O)(=O)Cl, OCCCC=COC1CCCCO1 to produce CS(=O)(=O)OCCCC=COC1CCCCO1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["C1CCOC1"], "agent": ["[Na+]", "O=P([O-])([O-])[O-]", "[H-]"]}
|
Using CNC(=O)COC(=O)N1CCN(c2ccc([N+](=O)[O-])cn2)CC1 to produce CNC(=O)COC(=O)N1CCN(c2ccc(N)cn2)CC1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOC(C)=O"], "agent": ["[Pd]"]}
|
Using O=C(Cl)C1CCCC1, CSc1ccccc1 to produce CSc1ccc(C(=O)C2CCCC2)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClC(Cl)Cl"], "agent": ["[Al+3]", "[Cl-]"]}
|
Using COC(=O)c1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Cl to produce O=Cc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Cl, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["ClCCl", "CO"], "agent": ["CC(C)C[AlH]CC(C)C"]}
|
Using CC(C)(C)[Si](C)(C)Cl, O=C(CC[C@@H](CO)NC(=O)OCc1ccccc1)NC(c1ccccc1)(c1ccccc1)c1ccccc1 to produce CC(C)(C)[Si](C)(C)OC[C@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OCc1ccccc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O", "COC(C)(C)C"], "agent": ["c1c[nH]cn1"]}
|
Using CC(C)(C)[Si](C)(C)Cl, Oc1ccc(O)cc1 to produce CC(C)(C)[Si](C)(C)Oc1ccc(O)cc1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O", "CN(C)C=O"], "agent": ["c1c[nH]cn1"]}
|
Using COC(=O)c1cc(Oc2ccc(C(=O)N3CCC3)cc2Cl)cc(O[C@H]2CCN(C)C2=O)c1 to produce COC(=O)c1cc(Oc2ccc(C(=O)N3CCC3)cc2)cc(O[C@H]2CCN(C)C2=O)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO", "C1CCOC1"], "agent": ["[Pd]"]}
|
Using Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl, CC1(C)OB(c2ccnc(N3CCNCC3)c2)OC1(C)C to produce Cc1c(-c2ccnc(N3CCNCC3)c2)nc2cc(F)cc(F)c2c1Cl, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["Cc1ccccc1"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using C1=C(c2cc3ccccc3[nH]2)CCN(Cc2ccccc2)C1 to produce c1ccc2[nH]c(C3CCNCC3)cc2c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCO"], "agent": ["[Pd]"]}
|
Using CCC(Cc1ccccc1)(C(=O)c1ccc(F)cc1)N(C)C, CNC to produce CCC(Cc1ccccc1)(C(=O)c1ccc(N(C)C)cc1)N(C)C, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CN(C)C=O"], "agent": ["O=C([O-])[O-]", "[K+]"]}
|
Using O=C1N(C(c2ccccc2)c2ccccc2)c2cccc(F)c2C12COc1cc3c(cc12)OCCO3 to produce O=C1Nc2cccc(F)c2C12COc1cc3c(cc12)OCCO3, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["O=C(O)C(F)(F)F"], "agent": ["CC[SiH](CC)CC"]}
|
Using O=Cc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1, COc1cccc(NC(=O)C(C)(C)C)c1 to produce COc1cccc(NC(=O)C(C)(C)C)c1C(O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1, please predict the condition, including solvent and agent in SMILES notation in json format like:
```json
{
"solvent": [
"CCN(CC)CC",
"CCOC(C)=O"
],
"agent": ["[Na+]", "[H-]"]
}
```
|
{"solvent": ["CCOCC", "C1CCOC1"], "agent": ["[Br-]", "[Li]CCCC", "[Mg+2]"]}
|
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