Datasets:

dotan1111

/

MSA-amino-10-seq

like 0

LLLLLLLLLLQQQQQQQQQQSSTTSSSSSTTRVATTTARAGGGGGGGGGGKLLLLLLLLVGGGGGGGGGGMLNAMMMILANDDDNNDDDDQQQQQQQQQQEEEEEEEEEEYYYYYYSYYLGGGGGSGGGGGGGGGGGGGGAEEEEEEEEESSSPSSSGSPVVEIVVVVVINDNNNNENNNKKKKKKKKKKTLLMQQQLLLPPPPPPPPPPSTTTSSSTTTSITTTTTMITSSQQCSSSSEIGGGVCVGGGVVVVVVVVIVKRRRRKRRRRFFFLFWFFFFIIIIIIIIVIQQQQQQQQQQAAAAAAAAAAQQQKQQQQQKLLILLLLTLLAPSEAAAPPEAGTTAATGGTAAAAAAAAAALLLLLLLLLVLLLLLLCLLLHHHHHHHHHHGGGGGGGGGGAEGGGGGEEGLLLLLLLLLLEKKKEEEKAKSSSDSSDSSD

FFFFFFFYFFTSSSSSSTSSLHHHHHHHHHPPPPPPPPPPLLLIILILLIREEEEEEREQKEEKKEKKEKVVVVVVVVVVQTTTQTTATELLLLLLMLLLQKKKKKKQKKGGGGGGGGGGTLRLLLLTLLVVVYVVVVVVHDDDHDNHDIDDDDEDDDDDEEEEEEEEEETVVVTVVTVVGTTTTTTGTTAAAAAAAAAAPPPPPPPPPPMMLMMLMMLMWYYWFYWWYWQPPPQPPQPQDDDDNSDQDAGTSSSSSGSSVVVVVVVVVVSTDDDDDSDDKRKKKKKKKKYYYYYFYYYYRRRPRRRRRRSRYHSHESHSTLLLALASLAAAAAAAAAAATITTTTTTTTRRKRRQRRKRTEPPTPSTPNFFFFFFFFFFEEEEEEEEEEKKKKKKKKKKAAAAAAAPAATTTTCTTTTSIIVLLVLLILDDDDDDDDDD

KKARKAKKKRIIIIIIIIIIMMMMMMMMMMDDDDDDDDDDSSSSSSSSHSNSNNNNN-N-KRRRRRR-R-FFFFFFF-F-KKKKKKK-K-DDNDNNN-N-QHQQQQQ-Q-SSCSSCS-S-SSSSSSS-S-VVAVVAA-V-TTTTTTT-T-PPPPPPPPPPCCCFFCFCFCVVVVVVVVAVTTTTTTTATTFFFFFFFFFFVVIVVIVVVVGGGGGGGGGGDDDDDDDDDDTTTTTTTTTTSSSKKSESKSTTTNNTSTNTTIVVVVVTVTEEAEEAEEEEFFLFFLFFFFRRRQQRQRDRSSSSSSSSSSQRRRRRRRRRKKKKKKKKKKNNN--DNT-T

LLFLLLFLLLV-VVVVVVVVD-DDDDDDDDNSNSNNNNNSIIVIIIVIIVPPTPPPAPPPTTTTTTTTTTLVIVLLILLVFIFFFIFFFIIVIVIIIMIVKKKKKKKKKKDDEEDDDDDDGAGGGGGGGGPPPPPPPPPPEAEEEEEEEALLLLLLLLLLQQQQEKQRQQLLLLLLLLLLYYYYYYYYYYYWWWFYWYYWLLLLLLLLLLIIIIIIIIVIKEEEEDEEEELMMMLQMQLTTTTTTTTTTTDEQEKLQEEEKSSSKKSSRSKTTTRRTRRTPPPPPPPPPPGGGGGGGAGGTTTTTTTTTTLILILQLLLITLLLTLLLLLFFFFFFFFFFLLLLLLLLLLVIIIRVVVVISSSSSSSSEDYIIIYLILLIEEEEEEEEEQHWWWWWWWWWSASNSKSKSAVPPPVPPPPPDDDDDDDDEDRRRRRKRKKR

GEEEEEEEEEQQYQQQQQQQFFFFFFFFFFAAAAAAAAAALVLLLLFLILMLLLLLLYLLEEEEEEESEECCCCCCCCACLLLLIFLLLLEEEEEEEEEERYLYLLLRLYVVVVVVVVVVAAQEAQAAAAVVSITSVIVVLLLLLLLLLLP------P--V------V--T------T--E------E--N------R--L------L--E------E--I------I--Y------Y--E------D--A------A--V------V--R------P--R------R--L------L--E------E--V------V--E------D--Q------Q--M------M--E------P--G------G--K------K--F------F--A------A--E------E--K------K--RRKRRARRRRDDDDDDDDDDTARSTRRTETTTATTVTTVNQQQQQQQQQQVFIFFVVVLFYYYFYYYYYYRHRHHRHRHHCC-CC-CCCCVL-LL-LVLLD---------TS-ST-TTTSSS-SS-SSNSFF-FF-FFFVSA-AA-AAAALVLVLLLLLLARARRARARRIIIVIIYIVVQEQEEQEQEEAAASSAAAASTTTTTTTTSTPSPPPPPPPPSPSSSSSSSSSNSRSSASSRDDDDDDD-DDGGGGGGG-GGFYFYYFF-FYRKRKKRR-RKTKSKEST-TNLLLLLLL-LLHQHQHHH-HHGGGGGGG-GGTNTAATT-TA

LLILLLLLLLTSEEEEETEEDDDDDDDNDNQQQQQQQQQQGGGGGGGGGGFFFFFFFQFFGGGGSGGGGGLLLLLLLLLLSSASAPASPSAAAAATAATASKGSGSGSSSFFYFYFYFFYIIIIIIILIINACACTANTTAAAAASCATAPPPPPPPPPPKKKKKKKKKKPPPPPPPPSPANSSSTGSSSLLILLLLLLLKKRERKRKKKSPPPPSPSSSRRKRKRKRRREEEEEEEEDEFFLFFFFFFFVVVVVVVVVVFFFFFFFFFFGGGGGGGGGGKKEKKKKKKKSATAMSTSSSKKKKKQKKKKL---------H---------G---------Q---------A---------V---------VLLLLLALLRNHHHHVMHSHVVVVVVIVVVKKKKKLKKKENNSNSKSNNNGGGGGGGGGEWFYLFFFWFYDEDDYGDDDMKNNNNKDKKKVVVVAVVVVV

RRRRRRRRRRLLLLLLLLLLG----GG-G-TTTTTTTTTTQQQQQHQQQQTGTTTTSTTTPPPPPPPPPPKQQQKKKKKQDNDNDDDEDNKKKKKKKKKKFLFFFFFFFFAAAAGAAAAADDDDDDDDDDPHPHAPPPPHFYFYFFFLFYGSGGSGGGGG----D---------H---------N---------F---------G---------P---------E---------P---------T---------I---------K---------S---------G---------R---------P---------L---------V---------E---------V---------Y---------H---------E---------L---------T---------T---------A---------V-----VVAVVVVVVVAAAAASAAAAIIIIIIIIIISDDDDEDDDDFFLFLFFFFFGVCVCGGGGVTTSTVTTTTTRRRRRKRRRRKQQQQKKQQQSAAAAAAAAAVVVVVVVVVTCVVVVCCCCVIIIIVIIIVIRSESSTTTSSAEAEAAAAAERRRRRRRRRRKKKKKKKKKKTTVTTTTTTTVAAAAVVVVAEEEEEEEEEE--M---------R---------A---------S---------E---------L-------ASSSTAASASKNKKKKKWQKPAAAAPPPPARKKKKRRKKKRNRNRRRRRNGGGGGGGGGG

HLHHHHLHHHHEEQEEEEEEEEEEEEEEEESAAAAAAAAAGGGGGGGGGGLILLLLLLLLPPPPPPPPPPAAAAAAAATAEVTEEVVALAIIIIIIVIVIGVGGGGGGGGLLIFLVLILIQQQQTQQQQQLLLLLLLLLLLLLLLLLLLLDDDNDDDDDDYYYYYYYYYYRRRRRRRRRRYYYYYYYYYYKKKKKKKKKKPRPPPPRPRPNDDDDDDDDDRRRRRRRKRRDDNDDHDHDNDDEDDDDDDELLLLLLLLLLHHNHKNHDHHKAKKKKAKKKNNENNNNNNELLLLILLLLLLLLLLLLLLLVVVVVVVVVVNSSSTSSSSS

DDDDDDDDDDPPSPPPPPPPQQQQQRQQQQRRRRKRRRRRGGGGGGGGGGLVLILLLILL-------G---------E---------P---------L---------V---------A--EEEEEEEEEESAAVAVAAAAFYFYYIYYFYAAAAAAAAAAKEKKKKKKKEIVIITTTIIVGEEPPPPEEEAAAAAPAAAALLLLFLFLLLLLLLLLLLLLDDDDDDDDEDNEDEEEEENQLLLLLMMLLLFFFFLFLFFFLLLRLLLLLLYYYYYYYFYYCAAAAAAACALILLILLMLIRRRRKKKRKRIIIVIIIIVIKKKKKKKKKKDDDDDDDDNDRRRRRRRRRRLMMMMLFMLMRRRRRRRRRRPPPPPPPPPPDDDDNDDDDDKKKKKKKKKKNNNNNNNNNNLLLLLLLLLMAAAAAAAAAAGGAGGGGGGGKKKKKKKKKKLMLLIIIMLLRQRQQPQTRR

QQQQQQQQQQDDEDDDDDDD---I------EEEEEEEEEEEEEEEEEEEEIVVIIILIIIEEEEREKKER-----I--I------G--G------I--I------R--R------Y--Y------D--D-QSQQQQQQQQRRRRQRRQRQAAAAAAAAAAAAAAAAAAAAIIIITVIIVI-----A--A------E--E------D--D------F--F------S--S------K--K------K--K------Y--Y------K--K------H--H------V--V------E--E------C--C------S--D------P--P------E--E------I--I------N--N------E--E------L--L------E--A------V--V------R--K------Q--Q------P--P------T--T------R--R-PPVPPPPRPPVVVVVVVVVVAQQAQQQQNQAAAATATTATRSSRSSSLSIDNNDNNNHNHTTTTTTTTTTLLLLLCLLLLDDDDDDDDDDAVIAVIVVVVNGGNGGGGGGQQQQQQQQQQSSVDSSSSSSLIILLMFLILYFFYFYFFYFAGSAVAVVAVARAHAAAAAATTTTTTVTTTTTTTQSTQTAIIIIIIIIIIGGGGGGGGGGMMMMTLMTLTEEEEEEEEEEKKYKKKKKKKVVIVIVLIVIAAAAAAAAAARRRRRKRRKRKKKKKVQKVKRQQRKKKKKK---------VTTTTNTTTTT

LLLLLELLLLNN-NNNNSNKYY-YYYYYYYLLLLLLLFLLGGGGGGGNSGDDDNDGDEDDAAAAASAAAVGGGGGGGGGGFFFFFFFFFFRRRRQHRRRRQYSTYYTSTTFFFFFFFFFFFYFFFFFYLFNNNNNNNNNNFFFYFFFFFFDDDDDEDDDDYYYYYYYYYYVFVVVVVVVVMMLMMMMLMMWWWWWWWWWFGGGGGGGGGGQQQQQQQQREDDSDDDDEDDCCCCCCCCCCMQWMQQMMQVAKAKKKAAKAAAAAAAAAAAGGQGGGGQGGEEQEEEEEEEAVAAVVSAAATVTIIVITILAAAAAAAAAAAAAASSAAAALLLLILLLLLGGDGGGGDGGHHHHHHHNHHLLLLLCLLLLHIFFIIFFFFLLLLLLLLLLTATTAVTTATTTTTTVTTTTAAAAASAAAARKRRRRRRRRDDDDDDDDDD

LLFLFFLLLIGGGGGGGSGGAAAAAAAAAAQQQQQNQQQQLLLLLLLLLLIIIIVVIIIIEEEEEEEEEDKKKKRKKKKKDDDDDDDEEDVIVVIIIVVIYYYYYYYYYYKKKKKKKKKKMLLMLLLLLLRRRRRRRRRKMMIMMMMMMMHHEHEEHHHHTTTTTTTTTTRRRRRRRRRRPPPPPPEPPPWWWWWWWRWWAAAAAAASSARPPRPPVRRPNNSNNNNNNNGGGGGGGGGGRRRRRRRRRRDDSDSSDDEDKKQKEEIKKKFLLLLLLLLLDDDDDDDDDDYYFYFFHYYYFFFFFFFYFFPPPPPPPPPPLQKLQQQQQQCCCCCCCCCCVVIVIVITTIPPPPPPPPPP

LFFFFLFLMFDDDDDDDDDDLIVLLILLLLEEEEE-EE-EVVAVV-VV-VSASSSSSSSSDDDDDDDDDDPPPPPPPPPPAAAAAAALSALLLLLLLLLLVVVIVVVVVVDDDDQDDDDQFFFFFFFFFFQQQQQQQQKEVVVIILIVLIPPPPPPPPPPWPWWWWWWWWRKKRRKRRKRDNSDNKNDNNGGGGGGGGGGAAAAAAAAAANNNNNNNNNNSAAAAAAASAG--G---N--Y--Y---Y--K--K---K--E--E---A--I--I---I--S--S---S--E--G---E--M--M---M--Y--Y---Y--L--L---L--F--F---F--N--N---N--H--K---K--P--P---P--D--D---D--V--V---V-----V------L--L---L--L--F---L--I--I---V--F--I---F--F--F---F--F--F---F--V--V---V--S--S---S--S--S---S--S--G---S--V--V---V--H--H---H--A--A---A--H--H---H--R--R---R--Y--Y---Y--R--R---R--VLLVVLVVLVDDDDNDDDDDWRRWKRWYRRLIIVIVIIIIGGGGGGGGGGQEEQLPQQPQSSSSSASSGSAAAAAAAAAAPPPPPPPGPPRKKRRRRRRRTTTTTTTTTTEEEEEQEEKEVVIVVVVVVTPPPPPPPPPPTSSPSDPTDSLLLLVLLLLVPPPPPPTPPPHQQHQQQHQQMMMMMLMMLMFAAAAAAAAAEEEEEEEEEE

IIVAVAIVAVILLLLLLLLLEEDDEDEDDDNNHHYHNHHYHHHHHHHHHHIIFIIIIIIIVEEEEEEDEEMMMMMMMMMMAAAAAALAAALLLLLLLLLLDDDKDRDDRDTTTTTTTTTTLLLVLLLLLLTTTTTTTTTT----E----E----F----F----D----N----N----N----S----S----A----A----Y----Y----S----A----G----G----E----E----S----S----A----A----E----E----D----E----K----K----E----E----P----P----L----L----L----L----D----D----L----L----E----E----S----N----G----G----K----K----V----I----P----ALLLFLLLLLLEEDDDEDDDDIILILIILIVTTTTSTTSTGYYYYYYYYYYKKRKRKKRKRIIIIIIIIIIGGGGKGGGGGRQQQDQQQQDKKKKKKKKKKEEDDDDDDDDRRRKRRRRRRDDEEEEEETERFFFLFFFFIYYYYYYYYYY-----N---------Y---------K---------V---------V---------V----TTSESETSESDDSSSSDSSSQQRRRRRRRRPPPPPPPPPPVVVVIVVIVIGGGGGGGGGSAATSKTAKTKQQQQQQQQQQQAAAKAATAKFFFCFFFFWFAAASASAASALLLSLLLLLI

IIIIIILLIIPPPVPVPPVVYYYYYYYYYYIIIIIIIIIIEEEEEEEEEEAAASASAASAEEEEEEEEEELLWWLWVLWWVVYIYVMMVVLLVIIIAVIITTTTTTTTTTEEEQEQEENEEEKKKKKKKETEEETEEEEEDDDDDDDDDNVVMMMMVVLMNNENENNTNDTTTTTTRTFTIIIIIIVIIIILLILMLLIITTSSSSSSASDDDDDDDDDDQQQQQQQQQQVVVVVIVVIILLLLLLLLILKKKKKKKKKKDNDDDDDDDDWWWLWLWWVLRRR-R-RR-RDDDDDDEDDDQQQQQQQQHQFFLLLLFFLLEEEDEDEEDDNNVNVMKKNNVKGGGGGGGGLLLMLLLLLLPPPAPAPPAPQQQNQQQQQQQQRRRRISRRYYYYYYYYLYIIIIYVLLIIAASSSAAASSHHHHHYHHHH

DDDDDEDDDDLLLLMLFLLLVVVVVVVVVVPPPPAPPPPPQQQEEEEQQELLLLILILLLEEEEEEEEEEVVVILIVVIITTTTATATRQKKKKKIKKKKEEEEEEEEEENNTNTNTTNNEEEEQEQEEEEEEEDEDEEELLLLILLLLLFFFLFLFFLLSSGSESSGSSAAAAAADAAACCCCCCCCCCAADASATQAAAAAQAQAAAQTTTTTTTTTSSSAAQAAAAAPPPTATAPPPSSLSSSSSSSTTTTATTSTTPPPPPPPPPPVVIGVAVIVATTTGTATTTASSSSSSSSLSEQMLFMFMMIEEKEDEDEEE

SSDSSSSSSNL-LLLLLLLLVVIVIVVIVIVIIIIVIIIIQSASAACASAE---------PPPPPPPPPP--S-S--S-S--N-D--D-NGGAGGGGGGGKKKKKKKKKKAATAAAAAATSSSSRSSRSSRRRRRRRRRRIIIIIVIIIIVLVLVVVVLVDADKDDADADEEEEEEEEEEVVVVVVVVVVVVIVIIIIVITATATTTTATWWWWYWWYWWASAATAATAAPPPPPPPPPPSKKKKKKKKKRKTRTRRTRTDSSSSDSSSSDDDDSDDSDDSSTSSSSSSTPPDPDPPDPDSSASSISSSS--N---------G---------G---------T---------V---------Y---------A-------YWYWYYWYWYQQTQQQQQQQ

VVVVIVVVVVGGGGGKGGKGVVVVVVVVVVQQQQQQQQQQRRSQSSRRSRCCHFFHFFHFLLLDLLDDLDSSSSSSSARSRKKKKKKRKKPPKPPKPPKPPPPPAPPPPPEEQQQRHQRKNNRNRKNNKNDDDDDDDDDDLLTLTT-ITIAAETAA-ASAKYYYYFYYFYLILLLLLLLLSSSTSSSSSSVVIVVIVVIVPPPPPLPPPP-------S-P-------G-G-------V-V-------L-L-------K-E-------R-R-------F-F-------K-R-------P-P-------I-V-------A-V-------H-H-------G-G-------V-VHQHHHHHRHRHHHHHHGTHHTTTTTTTTTTRR-RRKRLKRTT-THMTTMTDDEDEEDDQDIAVVLVVVVVLLLLLILLVLVIIVVIVVIVYYYYYHYYHYIIIIIIIIIIFFFFFFFFFFVVLLLLLLLLTTATAATSATKKRDKRKDRDEEEEEEEEEEEEEEEEEEEEGGGGGGGGGGNNNNQNNNNNRNRKRRRKLK---F------

YYYYYYYYYY-PPP-PPPPP-VVV-VVVVTI---I-II-IP---P-PP-PYYYYYYYFYYFFFFFFFFFFGGGGGGNNGGRRRRRRRRRRQQQQAQQQQQVIIIVIVIIFSTSTSSSSKSTSNNTSSSSTAKAAGAAPAASSSSSSSSYSIVVIVVVVVVVNVNVVVSNVIIIIIIVVIIYYYYYYYYYYWWWWWWWWWWAAAAAAAAAAIVVVIIIIVIEEQEEEEEEEAAAAAAAAAAPPPPQPPPPPIIIIIIIIIM-------V--MMMAMMMMAMIIIIIIIIIIMMMMMMMMMMIVVIIVVVIIKEDEKDHNEKGFFFSFFFFSIIIVILIIVPVVVVVVVVVVVVVVTVVVVVIVVNVVVVTVYYYYYYYYYYHHNHHHYHDHNEEEKEKKEE------Q---------F---------N---------L---------Q---------S---------T---------D---------N---------N---------E---------L---------D---------N---CCFCCFCCVCVVVVVVCCVV

KKKKKKKKKKKKKKTTTKKKAAAASSSSASDDDDGGDDDDYYDYFYYYYYENENEENDENMMPMGGGMMMDDDDEEEDDDTVAVVVVVTVTSNSVATTTTEEEERKEEEAGGGGGGGGGGNNNNQNNKNKGGGGDADGGGAMAAITTASADDDDDDDDDDPPPPPPPPPPNPPPPPPPNPNNNQDDSNNNIIIIIIIIIIPPPPSPPPPPHHHHHHHHHHRRRRRLRRRKIIIILLLLILLLLLLLLLLLAASAAAAASARRRRNNNRYRPSSSSSTSPSAAAAVAAAAAVIVVAVVVVVEEEEEEEEEEEEEEEEEEEERRRRRRRRKRDDDDDNDDDDQSQSQQQQQQGGGGGGGGGGAAQANNKTAT

YYYYYYYYYYRRRRRQRRRRGGGGGGGGGG-G---G-----A---A----RRRRDRRRRRMMLMMMMMMMYYYYYYYYYYK------K--S------A--L------L--Q------R--E------E--I------I--P------P--Q------Q--S------S--E------E--G------G--E------E--C------C--K------K--VVLL-VVVAVDDDDDDDDYNASEAASAAAADDDDDDDNEELLLLLLLLILEQGRRRRGRRESESES-ESSPPPPPP-PPPRHHHHHHHQHEEEEEEEEEELVLLLVLLLLILLLLLLILLRLRMHLTRMMALAAALAA--AAAAAAAAAAEDDDDDDEDDRQRRRQRRRRRARRRARRRRVAVAATATKKYVIIIVIIIIACCCCCCCCWQQQQQQQQQQPPPPPPPPPPSNSSENSSSSPPPPPPPKPPKKKKKKKKKKHQQQQQTQQQRRRRRRRRRREEAEEEESEELMLLLMLLLLKKKKKKKKKKDSDDDADDDDKEKKREKKKK

RSRQRRSRRRPPPPPPPPPPMMLLLLMLMMKKQQQKKKKKTLTTTTLTTTCCCCCCCCRCRRRRRRRRRRPPPPPPPSPPVVVVVVVVVVKKKKKQKKKKAASSAAAAAASSSSSSSSSSFFFFFFFFFFRRRRRRRRRRKKKKKEKKKKLLLLLLLLLIQQQQQSQQQQQQQQQQQQQQEKEEEEKEEERRRKKKQKKRFFIVVVIVVFIIIIAIIIIIIVIIIVVIIIVVIIVVVVIVGGLLLLGLLGDEAAAAEAAEGGGGG-G-GGVVRLM-V-LLLCCCC-C-CCTTTTL-S-TTEEESE-E-EAHHFFF-H-YYQQQQQ-Q-QQFYYYY-Y-NFLLLLL-L-LLQQQQQ-Q-QQKKKKK-K-KKLLAAA-L-PAVVFFF-V-VVGGGGG-G-GGARIIM-R-MMTTLLL-T-MMSAAAA-A-PALLLLL-L-LLEEEEE-E-EEAAGGG-A-YGD-DDD---DDF-YYY---FFKKTTT-K-KKAASSA-A-AAVVVVV-V-VVHFHHH-F-HHVVVVV-V-VV--GGG-----AAAAAAQAGACCCCCCCCCCASAA-ASAAAEEEE-EEEEEYYYY-YYYYYATAA-AAAAAGGGA-GGGGGRRRRRKRKRRLLLLLLLVLLIVVVVIVVVVEEEEEEEEEEFYYYYYYYYFLMLLLLLLLLVAAAAAAAASTTTTTETETT

VFFVFVVFFVAAAYAAAAAAAVAA-GA-AATSNT-VT-NTASSASAASSAHHHTHHHRHHEKEEEEEEKEFFFFFYFFFFIVVIVIIVVIGGGGGGGGGGQ----Q---QP----P---PV----I---IR----R---RF----F---FI----I---IN----N---QE----K---KA----A---AR----R---RI----L---LY----Y---YR----R---RVVVVIIVVVIIIIIIIIIIIQQQ-QQQQQKKLIRLRRLLPIIIIIIIIIIVVVVVVMVVVIIVVVIVVVILLLLLLLFLLPPPPPPPPPPAAAVAAVAAAMVMMMMMMLMLLLCLLCLLLTHHHHTHH-TAAAAAAAA-AMLLILMLLLMSSSSSSSSSSDDDDDDDDDDGWWMWAMWWPYFFFFFFFFFIIIIIIIIIIHYYYYHYYYHK--K-KK--KSIITTTTTITCCCCCCGCCCRRRRRRRRRRGGGGGGGGGGDDDDDDDDDDAYALAKLAAAEKEEEEEEKEVVVVVVVIVVRRRRRRRRRRDDDDDDDDGD

PPPPPPPPPPLLLFLLGLLLHHHHPHHHHHFFFFIFIFFILLLLLLALLAAAAIVAVIAAKEDEEREEEEYYYFYYYFYYRRRRRRRRRRRQQRRRRRQRSRSSSSTSSTLLLALLLLLLDDDNNDNNDGEEEEEEEEEEGGGGGGGGGGEEEEEEEEEEKKKKKKKKKKQKKKKQKKKKIIISGISSVSNTTDDNDDTDGGGGGGGGGGAAAGAAAGATEEEEDEDEEDTTTTTTTTTTNNNNKNNNNNEEEEDEDEEDLLLLLLLLLLLIIVLILVILFFFFFFFFFFEEEEEEEEEEGGGAGGGNGGLLLYMLMFLMSCCCCSCCCCTKKNNTNNKNLTTTTTTTTTRRRKRRRVVKPPPPPPPPPP

GGGGGGGGGGYYYYYYYYYYCVCCCCKCVVSSSSSSSSSSKQKKRRRKQQLMLLVVLLMMDDDDDDDDDDDSDDQQDDESFFFFLLFLFFYYYYFFYYYYDNNNEENENNWWWWWWWWFFRRKRRRRRRRDDDDDDDDDDKKKKKKKKKKTTTTTTTTTTLLLLLLLLVLLLLLVTLILLIVIIVVVVVVPGPPAPPPGSNSNNNNSNSSKKKKKKKKKKILLLLLLLIIHQHHHHQHQQFFFFFFFFFFPPPPPPPPPPDGGGGGGRGGDDDDDDDEDDTPPPPPPPPPVVVVVVVVVVGNGGGGGGNSKKKKKKEKKKDDDDSSEDDDQQQQHHQQLQEEEEEEEEEEGAGGGGGGAA

IVVIIIIIIIAAAAAAAAAANNKNNNNKNNKLKRKKKKKKWWWWWWWWWWFFFFLFFFFFHHHHHHHHHHGGGGGGGGGGRRRRRRRRRRL--------LGGGGGGGGGGWWWLWWWWWWMLLVMMLLLMTASAAAAAATFFFFFFFFFFHQQHHDQQQIRRRTRTRRRRLLLMLMLLLLVVVVVVVVVVDEEEEEEEEDKNNKRKNNKKPPPPPPPPPPAMMAAAMMASGGGGGGGGGGDDVDDDDDDDFFFYFFFFFFYYHYYYYYYYYYYYYYYYYYMMMLMMMMLMIIIVIIIIIINDDNNNEDDN-EEEEEEEE-TTTTTTTSTTSDDDDDDDDSSSSTTTSSATDDDDDDDDDEMMMMMMIMMMMSTTTTTTTCHHHRHHHHHHRRRRRRRRRR

LLIILLLLLLTTTTTTTTTTHYYYYYYYYHKRSKKRKKKREEEGEEDEEETGTTTTTTTGEEDDEEREEETGCASASSAGSFSSNFFSGYLLLLLLLLLLRRRRRRRRRRIIVIIIIIIIPPPPPPPPPPAAAAAAATAAKKKKKKKKKKSTTTSTTSTTLMLLLLLLLLSASSSASSNAPPPPPPPPPPEHKKEHHEKHGGGGGAGGGGQQRQQQQQQQGGGGGGGGGGIIVVIIIIVIYYYYFYYFYYAAAAAAAAAADDDDDEDDRDGGGGGGGGGGLLLLLLVLLLVLLLVLLVVLAAAALAALAAAEEEEEEEREEEEEEEEEEEWWWWEYWWWWMMMMMMMMLMRPRRRPRRRPTSTTVSETTSEEEEEEDEEEDAAADAADARVVLVVVVVVV

PPPPPRPPKPVVVVIVVVVVWWWWWWWWWWGDDDDDDDDDIIIFIIFIIITSSTSSTSSSSCCCCCCCCYPPPPPPPPPPLLLLLLLLLLIIILILLLLLSSSNSANSASYYYYYYYYYYLLLLLLLLLLITTLIALVVVDDDNDNNNNNAAAAAAAAAALLLLLMLMLMKKKKKKKKKKFFFFFVFFYFIIIIIIILLISSSSSSSSSSGGGGGGGGGGYYYYYFYFFYILFIIVIIFIHHHHHHHHHHEEEDEEEEESIVVVVVVVVVLLLLLFLLFLIIILIVLVVVEEEQEEEQEEDNNNNNNTNNWWWWWWWWWYLLLLLLLLLLENNEEEEEEEFLFIVFAFLFQSQQQQQQQQ

VLVVLVVVVVTTTTNTTTTTVVIIVIIIILPPPPPPPPPPLILLILLLLLFFFLFLFLFL--E-----E---C-----C---V-----V---M-----M---A-----A---N-----N---N-----N---G-----G---L-----L---V-----V---T-----C---F-----F---A-----K---S-----A---K-----K---K-----K---A-----A---T-----T---I-----I---A-----S---P-----P---G-----G---P-----S-HHSQHHSHSDHHMHHHQHQHERRRRRRRRRQQQQQQQQQQLLLLLLLLILDDDDDDDDDDYYYYYHYYYHAAAAAAACAAPPAPPPPPAPFFFFFYFYFYTTTTTTTTTTVVVVVIVVVIVVVVVLVVVV--YY-YYYYYPPPPPPPPPPIIIIILIIMIKKKKKRKKRKLLLLL-LLLLLLLLL-LLLLIIVLI-ILVL-Q--T------R--R------Q--Q------L--L------F--F------D--D------N--N------L--L------L--L------L--L------V--A------N--N------G--G------V--V------V--V------G--G------T--T-----VVVVV-VVVILLLLL-LLLLVVVVV-VVV-HHHHH-QHH-AADAAADAD-EEDEEEEED-FFFFFFFFF-KKKKKKKKK-KERKEKRKRKASSSSSSSSQSAASSSGSAMVVVVVVVVVVFFFFFFFFPFYYFYYYFYFYEESEEEAESEDDDNDEDDDDIIVVILVIVIGGGGGGGGGG

FFFF--FFFFGGGG--GGGGIVVV--VVVVQQEQQQQKQQRRRRRRRRRRNEEEQQEEEQNHNNNNNNQNNKNNNNTNKNDDDDDD-DDDADAQEEAQSANNSKNNNKNNPPPPPPPPPPKKKKKKKKKKEEEEEEEEEERRRRRRRRKRDEEKDDEEEDFFFFFFFFFFIIIIIIIVIIRRRHRRRHRRGGGGGGGGGGNSSSNNQSSNILLLLLLLILKK-KKKKRKKQA-QQQQQAQAAAAAAAAAASGGGSSGGGSQQNQQQNQQQVVIIIIIIIIQHHHHHHHEQIILIIIIIIIKKKKKRKKKKTTTTTATTTTEEEEEEEEEEFFFFFFFFFLGGGGGGGGGGLLLLLLLLLLVVVVVVVVVV

FFFFF-FFFFIIIIIIIIIIVVVVVAVVVVIIIIIIIIIIMLMIMMMMMMLLFLLFLLLLTTKTTKTTTTLLLLLLLVLLSSTSSTSSSSCFCCCCCFCYEEEEEEEEEENNNNNNNNNNSSSSSSSSSSLLLLLLLLLLVVVIIVVIVI--KEKKKK-K--MMMMMV-V--NHHNNY-Y--KKKKKK-K--DEDDDD-D--MLLMMT-T--QQQQQQ-Q--EEEEEE-S--RRRRRR-R--KNSRKK-K--QDDQDD-D--YFFFFF-F--IIIIII-I--KRRKRR-R--DEDDDD-N--GGGGGN-G--LLLLLM-LLLLLLLLLLLVVLIIVVSVANNNNNNNNNN

FFFFFFYFFFKKEEEEKKKKTSSSSSSSSTIIIVVVIINITNNSNNNNNNNNNNNNNNNNKKKKKKRKKKGGGGGGGGGGLLIIIILLLLVVIVVIVVVVTTTTATTTTTRRRRRRKRRRAAAAAAAAAAISTSSSSSPILLLLLLLLLLRSRRRRRRSRPPPPPPPPPPLLLLLLLLLLEEEEEEEEEELFLLLLILLLLRLLLLRRRLGGHGGHGGGGSSSSSSSSSSLLMIMMLLLLIVMVVVVVVILLLLLLLLLLHHHHHHNHHHEEEEEEEEEELITMMLIIILHHHLLSHHHQEEAEEAEEEEKAAAAAAAARLLLLLLLLLLVYVVVIVYYVKTSSSSSTTKIPRRRRKPPKLLLLLLLLLLHDDDDDDDDDFTTTTTVTTFQQQQSQQQQE

DMNYDMMMDMEEDEEEEEEETTTTTTTTTEGEGEGEEEEEAAASAASAAAFFFFFHFAFFRRRRRRRRRRDDDDDDDADDYYYYYWYYYYLLLLLLLLLILILILIVILIALAAALAAALSTNTNTTTTNFLFLFLLLLLQKQKQSKKQSAAAAAAAAAARRRRRRRRRRSTTKTTKKTTRR-RNRRRRRSS-SSPSSSSLL-LLLLLLLYY-YFYYYYYLL-LLLLLLVDD-DDDDDDDFFFFFFFFFFEDEEEDEEEDEEEEEEEEEETASSSATTHAQEQHQEQQEEQQQEQQQQQQKKKKKKKKKKQQQSQQQQQQTETTTTIT-QGGGGGGGG-GIVIIIVIIIVFFFFFFFFFFLLLLLLLLLLRRRRRRRRRR

DDTDDDDDNNQQEQQQQQ-QFLLLLLFF-LRPHPPHRH-HLLLLLLLL-LENNNNNYN-NHHHHHHH--HNDN-DNNY-NTTT-TTTT-TLRT-RRLR-TAVG-VVAA-GYYYYYYYY-YEEEEEEEE-QRQRKKKRR-RLLLLLLLLLLKTTTSTKKTTQQQQQQQQQQDDGDQDDDDGHPPPPPHPPPNNNNNNNNNN-KRRRR--RRQQQQQQQQQQFFFVFFFFFFSSSSSSSSSRCCCVCCCCCCHYHHYHHHHHELELLEEEEEVIIIIIIIIILLLLLLLLLLYYYYYYYYYYEEEEEEEEEEIVIIIIIIIITDNSSSSSSNEEEEKEEEEETTTTTTNTTTLLHL-LLLLLIVIIIIIIIINNGNNNSNNGQDQQNRQQQQQEEEEEEEEELIIIIILLII

SQSSFSSFQSFVFFYFFYVFVVVVVIIVVVKRRRRRRRRRTSTTTNSSTTLIIIIIIVILFFFFFFFFFFKKKKKKKGKKVIVIIIIIIIVNIVLIIIIVDDDDDDDDDDTTTTSSSSTTYYYYYYYYYYSGGGGGGGGSPPPPPPPPPPVVVVVVVVLVRRRRRRRRRRLLLLLLLLILGGGGGGGGGGGGGGGGGGGGAAAAAAAAAAQEQQKQQKQQPPPPAAAAPPRRRRSSSSRRDDDDDDDEDDRKKRRRRRKRTSSSESSENSLLLLFFFFLL--------W---------K---------V---------T---------E-DDDDDDDDDDLLLLLLLILLLLLL----LLRRRRKRRKRRNNNNQQKQSNQQQQAAALQQPPPPPPPPPPVVVVVVVVVVIIIIIIIIIIAGGAGGGGGAIIILIIIIML

TDDAADDVDAEEQEEEEEEELVIIIIIIIISTTTLTTCTTILIIIILIISAAAASAAAAAVVVVVVVVTIDEEEDQEDQEIILIIIVIILEEDWEEEEEEVAAAAAAASAGGGGGGGGGGPPEPPQPPEPLLLLLLLLLLVSIVVISIIIRRKRRRRRRRSGSSSSGSSSVQSTVSTTSTQQQQQQQQQQTAATTAATATNTTSSLTSTSNEEEEEEEEELMLLLLMLLLNNDNNNNNNNTYYYTFYYYYKRRNNKRRKNYSYYYYSYYYLLLLLLLLFLLLLLFLLLLLKKKKKKKKKKVTVVVVTVVVKQRQKKQKRQWWWWWWWWWWPKKPPKKPKPPPPPPPPPPPSSSSQQSSQG

SSGGGGGTGSIIIVIIIIIIGGGGGGGGGGYYTTYTHYTYVIVVVVVVVVAAAAASAAAALLMMIMILMLKKEEKKKKKKMMMLMGMMMMQQQQKQQQQLTTTTTTTTTTDDDDDDDDDDMMMMMMMMMMAVAAAPAAPVSDDDDDDDSDVVVVAVVVVVPPPPPPPLPPQQQAQEEQEQTVTTTTTTTTRSCCCCCCCCCCCCACACCCAAAAAAAAAAVVVVAAVVAVKKKKKKKKKKSRRRRRRRRRHHHHQHPHHHKRQQKQKRQRTTTTTTTTTTPPSPPPPPPPFFFFFFFFFFFVFFYFYTFTFFYYFYFFNFDDDDADDDDDRRKKRKRRKRDDDPDDDDDDTIIIVIIIIV

RRRRRQKRRRSSSSSSSSSSIIIIIIIIIIIFCFMFFMFFKKKKKKKKKKASSAAAAAAALIFILLLLMLSSSSTSSSGTMMMMMIMMMMAAAAAAAVAAKKKKEKKEKKYFYFYYYYYYKKKKKKKKKKYYYYYYYYYYEEEEEEEEDEGGGGGAGGGGRRRRRRRRRRKQKQKKQKKQCCCCCCCCCCYYYHYYYYYYHYHYHQQHHGRKRKQKKQKKEA-GAAAAAATMTTQATQTTFFFFFFFFFFDDDDDDDDDDYYYYYYYYYHYYYYFYYFYYWEEEEEEEEEDDDEGDDGDDTCTCTTTTTTCCCCCAACCATTTTVVVVTVQKQKHKKHKKEEEEEEEEEEMMMT-MM-MMLLIL-LL-LLNSAS-AA-APRRRR-RR-RRVVVV-VV-VVQRKR-IK-RKLLLL-FL-LIHHHH-HH-HH-E-E-VV-EV

LLLLLLLLVLRRRRRRRRRRVVVAVVVVAVGGGGSGGSGGTAAAAQAAATSSSASSSSSS----G--G------R--R------T--T------S--S------M--L------G--G------R--R------A--A------F--F------A--A------I--L------V--V------L--M------E--E------I--M------D--D------E--E------A--A------F--F------R--R------N--N------I--I------V--V------Q--Q--NNDNNNNNNNHFYHYRHYHHTTTTTTTTTTAASAAAAAAAT---------FFFFFFFFFFDDDDDDDDDDNNNNKNNKNNLLLLLLLLLLLLVLLLLLLLDDDDDDDDDDIVVIVIIVVIKKKQKQEKQQNEEEENNEENKKKRKKKKKKAAAVAAAAAAAIIIITTIIAVVVVVVVVVVTAAAAITAATLVVVVVLVTL--E-------DDDDDDDDDDLLLMLMMLMQDDDDDDDEDEAAAARAAAAALLLLILLILLLLLLLLLLLLSAAAAAAAAPCYYCYCCYCC

QQQQQQQEQQ-S----T----P----P----Y----Y----Q----Q----N----N----K----K---IVTLTTVTTTNNDNNNNNNNFFFFFFFFFFRRRRRRNRRRIIIILIIIIILLLLLLLLLLNERNSAENSNRRRRSSRRRRFFLFFFFLFLTTSTTTTTTSGGGGGGAGGG--------D---------F---------A-IVVVVVVVVVAAAAAAAAAADGGDGGGGGGRSNNNNSNNNFFNFVVFNVNAAAAAAAAAAGGDGGGADGDFFFFFFFFLFDNDDEENDEDSARSAAARAALLLLLLLLLLGGGGGGGGGGSSSSTTSSTSNNNSNNNQNNAAVAAAAAAAWWWWWWWWWYKKKKKKKKKKGGGGGGGGGGSSSSSSSSSSAAAAAAAAAANGNNNNDNNNLLLLMMLLLLSASWSSASTSYYFYYYHFYF

SSSSSSSSSSEEEEDDEEDELLLLLLLLLL------V---SSTSSSSSSSMYFMYFYFYFIIVVTVTVTIGGGGGGGGGGLLLLMLMLMLAATTATATATNNSSNSNSNNHHAAHANPYHQQSSQSQSQSLILLILILVLRRRRRRRRRRGGGGGGGGGGEEEEEEEEHE-R--R-R-R--V--V-V-V--L--L-L-L--D--N-N-N--T--V-T-V--A--A-A-A-GGSGA-GGTGKKKKK-KKRKPPPPP-PPPPSSTTS-STSSYYYYY-YNYYEEEEE-EEEEDDDDD-DDDDAVAAV-VAVA--KK-K-K--TTSSVSTSTTGGGGGGGGGHKKKKKQKKKKQQEEQEQEQQEEEEEEEEEEKRRRRRRRRRYYYYYYYYYYEEEEEEEEEEEEQREEEEEEVLPPLPLPLLSNSSNSNTNS----A-----DEEEEEEEEELLLLLLLLVVESSSSSSSSS

VVVVVVVVVVNNNNNNNSSNVSVSAVVAAVRSASRARRRAQQKQQQQQQQLRRRLRLLLR-Q-E------SLLLLLHLLLVDDDVNVVVDQQQQQQQQQQQQQQQQQQQQWWWWWWWWWWDDDDDDDDDDAQGAAGAAAGKKKKKKKKKKPPPPPPPPPPFFFFFFFLLFNEKKKKKKKKAAASAAAAAAIIIIAIITTILIIILILLLIRRRRRRRRRRNNNNNKNNNNEEEEEEEEEELLLLLLLLLLAVAAAAAAAMQKKKQEQFQKDDDDDDDDDDSEEESESAAEVALAVLVVVLAAAAVAAAAAYYYFYYYYYYSTSSSSSSSSEEEEEEEEEETVVVVLTVVVLLLLLILLLL

VVVVVVVVVVRRRRWRRRRWPPPPPPAPPSAAWWWWWWWWLLLLLLLLLLLLLLLLLLLLIIIVIIIIIIHHTHHHQQHNSSSNSSNNNQNNNNNNNNNNLLLLLLILLLLLMLLMLLLLQNQQQQQQQQAAAAAAAAAAWWWWWWWWWWDDGSNNSSSNLLLLLLLLLLLLILLILLLLLLLLLLVLLLKKRQRRRRRRVLVVVVVVVVEEEEKEEEKERRRWRRRRWRRRRRRRRRRRVVVVVVVVVVEEEEEEEEEEKKKEKKEEEKEKEEEEDDEEIIMIIVIIIVEEEDEEEEEEPPPPPPPPPPAAAAAAAAAAAAKAKKAAAK

PPPPSPPPPPGGGGGGGGGGGGGGGGGGGGNSASSSSSSSTTTCHCTTVQEEEEEEEEEEYYYYYYYYYYVVVVIIVIVVIIITISIIVSKKKKKEKKKKAAQAAAAAASLLLMLMLLLMIVTIVIVVVIYYYYFYYYAYAAAAAAAAAALLLLLLLLLLKKRKKKKKKKNRNNLNNRNNRARRQRRRRRCNVCCCCCCCRRRRRRRRRRFFFFFFFFFFSSSSSSTSSSEQEEQEEEEEIIIIIIIIIIRRRRRKRRRKGGGGGGAGAGHEKEEEEEET-D---------V---------L---------P---------V---------V--------DDDDDDDDDSLRLLRLMLLLNNNNNNNNNTFLYFLFLLLF--------L---------I---------F-LQLLLLLLLLVVVVVVVIVVPPPPPPPPPPLLIILVVLIA

QQQQNSQQSQPRPPPPPPPRLLLLLLLLLLSSSSSSYSSSDDDDDDDDDDLLLLPLLPLLAAAAASADSAEEEQEEEEEEGG-------EEE-------EII-------IRK-------RLL-------LLI-------LKK-------KRK-------RKK-------KKK-------KTT-------TGG-------GLL--------LL-------LVV-------VFF-------FIL-------ISS-------SPP-------PLL-------LAA-------ALL-------LIA-------AVI-------INNNNNNNNNNNSNNQKQQKNTTTTTTTTTTQQSSRRQREQASSDTASTASVIIIIILIIIQQQQQQQQQQIIII-II-IIRNRRRRRRRNSTSSCSSSSSLLVVLAILALEEEEEEEENEDNKDDDDDDDRRRRRRRRRRRRRRRRRRRRTTLLTTTTTT--VV-V--V-EEEEEEEEEEGGGGGGGGGGNNNNNNNNNNRRRRRRRRRRKKKKRKRAKKAAAARAPQAAFFFFFFFFFFYYYYYYYYYYLV-------V

EEEEEEEEEEQQQKQQKQRQKKKKKKKDKKEEEEEEEEEEAAAAAAAAAAVVVVVVVIVVSSSNNSNSSSNNNDNNDNNNVVVVVVVVVVVVVVVVVIVVSSSSSSSSSSIIIIIIIIIINSSSSSSNSNMLLLLMLMLMRRRRRKRRKRLIIVIIILILILLLLLLLLLVIIVVIVVIVNNNNNNNNNNAAAAAAAAAALFMILFLLFFEEKNKENEKETT---T-A-TAA---A-A-AAA---V-A-AVVVVVVVVVVVVAAAVAVVVIIVTTVTIVIMMMQMMMMLMGGGGGGGGGGIVVVVVVIVVEEEDDEDEEDGGGGGGGGGGGGGAGGAGGGYYFCFYCYFYQAAAAAAQAQ-----R---------K---------N---------I---------S---------S----AEQQQEQAEERRRRRRRRHQLLLLLLLLLL

WFYYYYFFFYKTKKKTKTSKSTSSSTSTTSDRDDDDDDDDHHHHHHHHHHHHHNHHHHHHSRSTSRKRRSFFFFFFFFYFYYYYYYYYYYQQQHMQQQQH-V---V--V-YYYYTYYYYYLTLVLTLLTLKKKKRKLKKKRKRRRKRRKRVVVIVVVVVVTTTTTTTTTTDEDEDDDDDDYYYYYYYYYYVVVLVVVVVVGGGGGSGGSGWWWWWWWWWWGGAGGGGGGGLQLILQLQQLVVVIVVVVVVLPLLLPIPPL-NNN-N-NNNGGGG-GGGGGEEEE-EEEEQSSAT-TSSTSRRRR-RKRRRPPPP-PPPPPDDDDDDDDEDGGGGGGAGGSGGSGSGGGGGVLVIVIVVIIVVVVVVAVVVRRRRRRRRRR---H-----HAAAAAAAAAAAAAAAVAAAA

AKAKKKATAKEEEEEEEEEEKLKLLLKLKL---RK--------RS--------HQ--------YY--------VV-----RRRRRRRRRRIIIIIIIIIIIIMVVVIIIVEEEEEEEEEQYYHYYYYYYYIIIIIIIIIILLLLLLLLLLTTILLLTTTLMIVIIIIIIFILIVVIIIIIIIMSIIMIIIRRRKKKHRRRYYYHYRYYYYDDDEEEDEDEGGGGGGSGGNAAAAAAAAVAEEIEEEEEEEVIVIVMVIVVRKGKKKKKKKEEEEEEAEEENNNHHNNNNNFFFLLLFFFLEEE---EEV-EEE---EED-ATATTTAVTTFFFFFFFFFFYYYYYYYYYYEEEEEEEEEEACAATAAAAAYYYYYYYYYYPPPLLLPPPLIIIVVIIIIMTTTPTTTTTTGGGGGGGGGGRKRRRRRRRK

TTTTTTTTTTLLLLLLLLLVITFITIFFFFVVVVVVIVIVVAKAAAEEEEQQLQQQLQQLVVVVVVVVIVIIIIIVIIIIVVIVVVILLLKKKKKKKKKKSSTSSSTSSTVVIIVVIVVVKRKNRKKKKKLYMMMMMMMMDDDDDDDDDDLLLALLLLLLYYFYYYYYYYEEEEEEAEKTWWWWWWWWWWFFFFFFFFFFVVVIVAVVAVTTTTTTTTTTKKPRKKPKKPSASAASSSSSAAAAAAAAAARRRRRRRRRRRRKRRRKRRKDDDDEDDDDDGGKGGGKGGGWWWWWWWSWWDNDDDDDDDDIIIIIVIIIIKNGNNNNNNNEEKEEEEEEELLVLLLVVVVFFFFFFFFFFLLLLLLLMLLQNRHHHHHHHMMMMMMMMIMTTSTTTSSSSRRRRRRRRSKGGGGGGGGGG

GGGGGGGGGGVVIIIVVVVVVVVVVIIIVVS---------L---------E---------R---------F---------KKKKKKKKKKPPQSQPPPPPVIVVVLLLIVLLLILLLLLLKKKKKGGGGARRRRRRRRRREKRRRRRRRRYYYYYYYYYYRRRRRRRRRRDDDDDDDDDDVVAFAVVVVAKEEEEEEEEEDDDEDDDDDDGGGPPGGGGGYYYYYYYYYYLLLLLGLLLLKKIKREEETKLLLLLLLVLLRMRRRRRRRRAAVVVVVIIAEEEEEEEEEEHHHHHNHHHHYYYYYYYYFYPPPPPHPPRPLL--------II--------IIVVVVVVVAAAAAATAAAAQQQQQEEEEQNKKKKKKKKKTTTTTTNTTTKKKKKKKKRKHHHHHHHHHHVVIIIIIIIIEELLLLLLLL

ILILIIIIIIVVVVIVAVAVPPPPPPPPPPVVTVVVVVVVAGASCSCCCSA-A-------E-D-------K-K-------I-I-------VVAVVVVVVVWWWWWWWWWWYYYYYYYYYYTTTTTTTTTTSSSSSSPSSSAAAAARAAAARRRRRRRARRMMMMILLILMYYYYRHRRRYEKEKEKKEKKSSSSGSTGSEAAAAAAAAVAFFFFFFFFFFVVVVIIIIIVCACAAAAAACFFFFFFLFLFRSRSSSSSSRSSSSSGSSSSVVVVILIILVLLLLLLLLLLAAAASASSSAVVVAVVVVVVQAQATPAAAAAYAYYYYYYYGAGAEAEEEGSNSAAAAAAAGSGSAAAAAS

ASAAAVAAAAE-E-E----EFFFMFFFFFFKRRRRKRRRRGGGGGSGSGGAGAGGGGGGALLLLLLLLLSSSSS-SSSASPPPP-PPPPPGGGGGGGGGGATAAAAAAAATTTTSTTTTTILVMIMMMMIWRWRRRRRRWFLLLLLLLLLPPPPPPPPPPYYYYYYYHYYNNNNNQNQNNGGGGGGGGGGCCCVCCCCCCDDDDDDDDDDLLLLLLLLLLSHSHSHHHHSEEEEEEEEEELLLVLIVIMLKRKRKRRRKKEEEEEEEEEETSTTYTTTTTTTTTTTTTTTEEESERSREESSSSSSSSSSSSSASAASSSYYYSYYSYHYKQQQQQQQQQAAAAAAAAPVRRRRKGRGRREEEEEEDEEELILILIIILLNSKSTASATTFFFFFFFFFF

MMMMMMMLMMDDDDDDDDDDGNGGSSSGSSNNNRNKNNNNAAAAAVVAAAGGGGGGGGGGEEEEEEEEEEGGGGGGGGGGRTTTT--RK-HHHHHHHHHHLLMMLLLVLLLLLLLLFLLLRRRKRLLRRLVVVVVVVVVVEEAAEEEEEEDEEEEEEDEETNSSNSSTSS-R--RCC-RCNTHYHHHHH-TTTTTTSTTTSSSSSTTSSSTNSSDKTTNTCCCCCCCCCCDGGGGGGDGGLLLLLLLLILQQQQQNNQQQSTSSTSTSTS-S--SSS-SSNNNNNNNLNNKRRRRRRKRRSSNNSAAV-ARRCRRRRRRKLLLLLLLLLLIIIIIIIIIIRLLLLMMRLMIILLIIIIIIPSPPPPPPPPKSTSSSATSSDNDTNEEDDDPPPPPPPPPP--II--------SS--------PA------LLLLLMLLLL

MMMMMMMVMMDDDDDDDDDDNNNNNNNDNNVVVVVVVVVVISSSTSISSSSSSSSSSSSSPPPPPPPPPPGGGGGEGGGGLIIIIILMMIRRRKRRRRRRMMMMMVMMMMCCCCCCICCCMLTTMTMTTTPPPPPPPPPPIIVILIIVVIMMMMMLMMMLAAVAAVAVVVLIILLILIIIKTKKKKKKKKAAACAASAAADDDEDDDDDDEEEEEEEEEEVVVVVVVVVVNDDNNDNDDDQRQQQLQQQLAAGAAAAGGAGSKSSSSNNSLLLLLLLLLLLQQQQQLQQQTSSTTNVSSNRHYHHHHYYHVVVVVVVVVVEEEKKAKEEAKKKKKKKKKKKKKKKKKKKKHLLLHVHLLLQHNHHDQNNN

RRRRRTRRRTRRRRRRRRKKWWWWWAWWWAAAAAASKAAAYHQEHEQEEEIVVVVVVVVVGKRKRRKKKRVVVSVVVVVVRRRRRRRRRRKKKKKKKKKKAAGGGGGGGGIIIIIIIIIVKKKKKKKKKKTTITIATTTATTTTTATTTADGGNGGNNNGKKKKKKKKKKTTAAAAASAAGGAAAAAAVARRTRTRRKRVPPPPPPPPPPTTTTTTATTTKKKKQTKKKTTTTTTTTTTTSSSSSASSASVVVVVVAMVIVVIIIILIIIHHHRHHHHHHKKKMKKMMMKRRRHRRRRTRSSNNNNNNNNRRRRRRRKRRTTTTTSSSSSKKKKKKRKKKLLRRRRRRRRYYYWYYYWYY

EEAEEEEAAELLLLLLLLLLGGGGGGGSGGDNDDDNNDDDFFFFFFFFFVRRRRRRRRKRRRKRRRRRRRRRSKRRRRRKEEEEEEEEEEIIIIIILIIMWWWWWWWWWWRRRRRKRRRRCCCCCCCCCCSSSSSGSSSSSSSSSSSSSSSSSSSNSSSSDGDDDGDDDDKKRKKKKRRKTNTTTDNTTTTTSTTTTSSSAARAAAARRAFFFFFFFFFF--K----QQ---P----PP-SSASSSSAASGGGGGGGGGGIVIVVIIILLVVVKVVVVVVIIIIIIIIIIALAAALAAAAIIIIIIIIIVGGGGGGGGGGRRRRRRRKKRHHNHNHHNSHQHHHHHHRHHEQEEEEEEVE--------P---------A---------N---------L---------L-QQQQQQQLRQKKKKKKKTKKN---------

DE-D-E-EE-EEDEEDEEEDWWWWWWWWWWQNNQNNNSQNNHHNHHHNNHMMIMMMMIMLSSSSSCSDSSSSFSDSFSSDYYHYHYNYYHQQQQHQQQQHQESLEEEEEEEEEDEEEEEERRKRKRKRRKGGGGGGGGGGKAKQQAKQQQTTTTTVTTTTKRRRRKRARRNNDNNNNNNNYYYYYYYYYYIIIIIFIIIIPPPPPPPPPPEEDEEEAEEEPPPPSPPPPPAAAAAAAAAATHRHHHHHHHQERQKERQQRKKKKKKKKKKEDDEDPDDDDRAKRRRKRRRFFFFLFFFLLDNNDNNNNSNVVTVTVTVVTLLLLALLLLATTTTATTTTTFFFFFFFFFFLLLLLLLLLL--L-L-L--L--L-I-L--I--Y-Y-Y--Y--P-P-P--P--G-G-G--G--L-L-M--L--T-T-T--T--G-G-G--G--T-S-S--S--R-P-R--T--R-R-R--S--K-R-K--R--E-E-E--E--T-S-A--A--F-Y-F--F--K-R-K--K--I-I-I--I--M-F-F--F--E-E-E--E--E-E-E--E--F-F-F--F--S-D-S--S--S-E-S--S--K-R-R--R--S-S-S--SGGNGGGGNGGKKKAKKKNKKLLMLVLVLLVGGGGGGGGGG

GGGGGGGGGQLLLLLLLLLLRRRRRRRRRRNQLQKKQRKQSTSSSSSARSYFFYFLFFLFVVVVVCVVCIEEEEDDEEDEVVVVIIIVVICRRHRSRRSRAAAAAAASAAESPESSEPSEALMAMMAMMACCCCCCCCCCGGGGGGGGGGVVTVVVSAVV---------L---------S---------N---------F---------L---------K---------T---------A---------A---------L---------I---------V---------K---------Y---------F---------T---------N---------D---------A---------T---------E---------V---------K---------A---------K---------H---------N---------V---------D---------D---------L---------Y---------N---------G---------R---------K---------A---------W---------EGGGGGGGGGGSSSSSSSSSSLLFLLLLLLLLLLLLLLLLLDDDDDDDDDDQQQQQRQQQQTTTTKTETTTVAAVAAVAAVYYYFYYIYYLVVVVVIVVIVTTTTTITTTTNSNNNENNQNTTTTATTTTSV-VV--VV-VM-MM--MM-ME-EE--EE-EV-VV--LT-VT-QT--TQ-TGGGGGGGGGG

KSFSSSSKSSGGGGGGGGGGLLLLLVLLFLANSAAAAAAAASSSSSSSSSAAAMAAMAAIYILTITTYLSQKQQQQQQQQRRRRRRRRRRKKKKKKKNKKPPPPPPPPPPKKKKKKKKRKKRRRRRRRKRRRRRRRRRRRTQQQQQQSQQEEEEEEEEEQTTTTTTTTTTSSSTSSTRSTCCCCCCCCCCRNKNNNNRRNLLLLLLLLR--A-AAAA---LLLLLLLLLLSKKKKKKKKKITIQIQQIIQPSPSSSS-SSLLLLLLM-ILEATSEAS-ESKKKKKKK-KKLLLFVFF-LFSSSSSSS-SSVIVVIIVVVVVVVVVVAVVVSSSATSASSA

TTSTTTTTTTEEEPPASEAAFYFFFFFVFFTTTTTTTTTT---------I---------V---------K---------L---------R---------V---------E---------E---------S---------D---------D---------F---------S---------A---------V---------K---------V---------L---------Q---------K---------N---------A---------P---------T---------M---------L---------D---------V---------Q---------I---------K---------V---------D---------V---------R---------T---------E---------N---------RNNNNNNNNNNIIIIIIIIIVEEEEEEEEEETTTTTTTTTTTTITTTTINTYHHHHHHHHHEEEEEEEEEEKKKKKKKKKKLMMMMYYMMMWWWWWWWWWWLLLVVVVLVVNNYFFYFYFFPPPPPPPPPPLLLIILLLILAAASSSSASSTTTKTTTTTTPPPPPPPPPPHHGQQQQGHHQQKKKKKKKKLLLVVVILIL---F---------K------KKIKKKKIKKRRRRRRRRRRSSSSSSSSSSDD--------RRRHHHHRRRGGGSSAAGEEAVVIVVIVVVYYYYYAFFYYFFFFFFFFFFLLLIILLLLLKRKKKKTKKKGGGGGGGGGGLLLLLLNLLLIIIVVVVIVVGGGGGGGGGGYYDDDDDDDDPPPPPPPPPPHHHYHHHRHHEEEEEEEEEEEEEKEKKEKKSSSAAESSSS

EEEEEEEEEEEDDDEDDDDDPPPPPPPPPPQDEDQDDDDDVVRVVVVVVVEEEEEEEEEENNNNNNKKIHKHKHKHHHKKPPPPPPPPPPLLLLLLLLLLCVCVCVCCCCNNNNNNNNNNTHTFTHTTTTEEEEEEEEEELILILILLLLIVIIIIIIVVQNRRQKRRRRAAAAARAAAAKEEEEEEEEELVVVLVVVVVLLLLLLLLLLIIIITIVCIIDDSDDDDDDDKRRRKRRRRTDNNNDNNNNNRRRRRRRRRRGGGGGGGGGRKVKVKVVVKKKKQKKKKKKKKKKKKKKKKKGGGGGGGGGGKKKKKKKKKKSVSSSSSSSSSTSSSSSSKARRRRRRWRRKSSAASSNNTT

HHHHHHHHHHPPPPPPPSPPVVVVVVVVVVIIIIIIIIIILLLLLLLLLLIIIIIIIIIITTTTTTTATTGGGGGGGGGGPPAPPPPPPPVVVVIVIVVVSSSASSSSSSIMIVIIVIIMAEEEEEAEEEMMLMMMMTMVIIIIIVIIILKKKKKKKRRKEEEEEEEEEEVVIVVIVVVTPPPPPPPPPPNN-NN-N--SHHFHHFHFFHVVVVVVVVIVAAAAAAAAAATTTTNTTTTTMMMWMMMMMMQKKRRRRRRKKKRKKKKKKKKKKKKKKKKKIVGGFGGGGIEEEEEEEEEEKKRKKRKRRKLLVLMVLIILKKKKKKNRKKHSHNHHHHHAGGGGGGGGGGAAAAAAAAAACCCCCACCCCPPPPPPPPPPSSESSESEESHHNHHQHQQHPPPPPPPPPPVVVVVVVVVVNNNNNNNNNNFFFFFFFFFFLLLLLFLLLL

SSSSSSSSSSEEEEEHENHEYYYYYFYYFYIIIIIIIIIIASAASASAASKKKSKSKKSKAAASA-AA-ELLLLL-LL-LLLLLLLLLLLEEEEEMNEEEQQQEQQQQWQLLLVLVLLVLAAAAATVATAGGGGGGGGGGQQQGQGQQGQPPPPPPPPPPCCCACACCVCASAASAAAASV-----V---S-----S---VTAFVFVFFVAAAAATAATARRRRRRRRRRRRRRRRRRRRLILLILYLLIVIIIILVIL-LLLLILLLLLVVVVVVVVVVKGGGGGKGGGRRRRRRRRRKFFFFFFFFFFKKQQKQKQQKAAAAAAAAAAFIFCICFFAISTTTTTSTTTEPDDPDEEDD

QQSTQQSQQSPPPPPPPAAPYYYYYYYYYYFFFFFFFFFFDEDDDDDDDDFFFFFFFFFF-Q--Q-----DDDNDDDDDDLLLLLLLLLLGGGGGGGGGGDDDDDDDDDDYYHWYYYYYYTTTTTTTKTTQQQQMRLLLQTTSTTTSTTTTTSSTTSTTSLMLLMLLMMLLLLLLILII-QQQQQQQSS-FFFFFFFFF-YHHHPYHNN-VVLLVVLVV-VVAVVVVLV-AAAAAAAAA-DDDDDDDDD-VVTTVITVV-TTGITMGRT-AAAAAAAAA-AATSAATAP-IIVVIIVII-SAKAASKAA--K--A------D--D------V--L------I--I-----AAAAATAAA-QMQQQYQQQ--MLLR-LLL-GGGGGGGGG-AQAAQASQQ-KKKKKRKKK-QKHHQQGQQ-DDDDDDDDD-KKKKKKKHK-LLILVLLRL-

QDQDQQDDDDHNNNHNNNNNNTNSNSTTTTGGGGGGGGGGIIIIIIIIIIEEEEEEEEQEGGGGGGGGDGEDEEEEEDEEVAAAIAASGAPPPPPPPPPPDNDDDDS-DNAFAAAAA-AFNNNNNNLNNNNDDDNDDDNDWVEDEEVVEVIIILIIIIIIRRRRRRRRRRTTTTTTTTTTHARRRRSTRTFFFFFILFFFPDPPPPPPPPIAIIIVAAT-TKKKTKKKKKLMIMLMMMQMNNNNNNNNNN-PPP-PPPPP-GGG-GGGGG-VFV-IVVVV-LLL-LLILL-RRR-RRRRR--GS-SSSAS-SKK-KKKKK-HHH-HHHQH-FCF-CFFFF-GFA-AAGAA-IMM-MVIII-CCC-CCCCC-TTT-TTTST-STT-TSSSS-III-IIIII

HHHHHHQHHQQQQQQQMQQMQQRQRWKQRREEYEYNYEYY--S-S-L--SSSSGSSSGSSKKKKKKKKKKGGGGGGSGGGLLLLLILLILPSSSASASSAIVVVVVVVVLLLLLLLFLLLIVFIFLFIFFDDDDDDDDDDAAALAAAAAANNNNSNNNNNKKKKKKKKKRRRRRRRPRRRNNNNNGQNNNLLLLLLLLLLYYRYRYRYRRLLEVLMLILLVVVVVVVVVVPHHHHHHHHHCCCCCCVCCCAAAPAAAATANNENLNFKNLDD-DDDDEDDDD-DDDDDDNAA-AAAAAAAKK-KRKKKKKHH-HHHHHHHGG-GGGGGGGRRRRRRR-RRWWWWWWW-WW

EDDDDEDNDTLLLLLLLILLDDDNDDDDDDKKKKKKKKKKTTTTTTTTTTAAAAAAAAAAVVVVVAPVVASSSSSNSSSSFFFFFFY-FFEEEEDEE-EEGGGGGGG-GGGGGGGGG-GGMVMMMMM-MMCCCCCCC-CCLLLILKL-LKRHHHHHH-HHQQQNQQQ-QQHHHHHKH-HKIVIAIII-VIVLIVLVL-LVLLLLLLL-MLTTTTTTT-TTKKKKKSK-KSDRDDDDD-DDAAAAASA-AALMLLLLL-LLTTTSTTT-TT-----I---I-----A---S-----T---T-----Q---QKGKRKRG-GRDDDDDDD-DDVTTTTMT-TMAASAAAA-SARRRRKTR-RR

QQQQQQQQQQCNFYNCYNNNFFFFWFFFFFDDDDDDDDDDRRRRRRRRRRHQQQQQQQQQEEEEEEEEEEIIIIIIIIIILILLLLLLLIQEEQEQQ-EEVSSSSTSSSSYYYYYYYYYILLLLLLLLLLPPPPPPPPPPYYYYYYYYYMAAAAAAAAAANNNSNNNNNNYYYYYYYYYYFVIFLFFMIISRSSGSSGGGLLLLLLLLLLYHHYHYYHHHEKEEKEETKKPPSPPPPPPPVVVVVVVAIVQEKEEQQEEEVAVVIVVVVASAAAVAAAAAQRKKKKKKKRTVTTTTTTTVLFLLLLLLLYMMMMLMKLMMFYWYYFFYYYEDDDDEDDDDFFFFFFFFFFKKKKKKKKKKGGGGGGGGGGDDDDDDDDDDIIIHLIIIIIQQQQQQQQQQRGRRRRRRRGESSENEENSPAAAAAAAAAAFFFFFFFFFF

EEEEEEEEEELLHLLLLLLLQDEDDEEEDERRRRRRRRRRHRHHHLHHHHKRKRRRKKRRAQAQQQQGQQESDNNNDDNNAEAEEATAEALLLLLPLLLLLLLLLMLLLLMQLQQQMLQQQQQQQQQQQQGGGGGGGGGGLLLLILLLLLQVQVVAQQVVASAAAEEAAEVVVVVVVLVVLLLLLLLLLISSSSSSSSSSAAAAAAAAAAKKKKKRKKKKLIIVIIIIIIFFFFFFFFFFGGGGGGGGGGTSTSSITTSTGGGGGEGGGGKKKKKKKKKKVIVLIIVVIIEEEEEKEEEKQPQPPPQQPPQEEEEEEEEEASASSSAASSIIIIVITIVIAVAAVAAAAAEEEEEEEEEE

KKKKKKKKKKWWWWWWWWWWVVVVVAIVVV-----T----DDEDGEDDDDLTLILIIIILIIVIIILLIVIIIIIVIIII-K-K-K--K--D-D-N--N-TTTTTTTTTTSAAAAVAAAA------S---VVVVVVVVVI------II--------HH--IIIIVIIIIVRRRRRRRRRKVIVVVLVVIVSSSSSSAASSWWWWWWWWWWAAAAAPLAPANPPPNPPPPNKRKRKRKKRKGGGGGGGGGGIVIVIVVVVIRRRRKLRKKKVVVVVVVVVASSSSSSSSASAAAAAAAVAANEQESQQQQTDNDNDNDDNDDDDDEDDDNDTTTTTSTATTPPPPPPPPPPRRKRRRRRKRTTTTTTTTSTGGGGRAGGGGIIIIIIIIIINNNNNNNNNNYYYYYFHHFYLCFCLILLILSSSSSSSSSSRYRRRRRRRR

VVVVIIIVVVMTMT--MMTM-N-N--N-N-VVVVVVVVIVAAAGEAEAGALLLLLLLLLLRRRRRRRQRKLLLLLLLLHLLLLLLLLLLLIVVVVVVIVINNHNRYHHNHVIVIIMIIIVIILIIIIIIIFFFFVVFFFFRRRRRRRRRRKRLKKRKKKLDSDSSSSDSDEKKKEEEEKKAAAAAAAAAA-N-N----D-SSSSNNNSSSCCCCFFFCCCGGGGAGGGGGASASSAAAAAGGGGGGGGGGI-I----I-IS-S----S-SGAGAGGGGGGAAAAAAAAAAAAAKSSACAAATSASSSAAS----QAA---GGGGGGGGGGSSSSSSSSSSAAAAAAAAAAANSSTVTASSQ------Q--L------L--R------R--G------G--T------A--E------E--K------K--D------D--S------S--K------R--K------K--A------A--R------R--LLLLVVVLLLKKKKKKKKKRAAAAVAAAAARRRRRRRRRRAAAAAAAAAAMMMMMMMMMMMYYPYYYYYYLLLL--LLLYVTVV--VVVV

-------F---------V---------P---------R---------V---------T---------I---------N---------I---------L---------A---------Q---------V---------L---------R--NHNHNHNNNNLSLTLTLLLLKKKKKKSKKKPPPPHPPPPP--------P-TTTATCTTTTAEAE-EAC-AQEQE-EQQ-QAFAFFFFAFAGEEEEEEEEGAEEEEEEEETIIIIVIIIVIEKEKEKKEEEVVVVVVVVVVPPPPPPPPPPKKKKEKKEEKGGGGGGGGGWNNNNNNNNNTPQPQEQQPEPNNNNNNNNNNAAAAAAAAAAIVIIIIIIIIKKRKKKKRKKKKKAKKKKKKHNNNNNNNNHGGGGGGGGGGNNDNNNNDTNLIFVLVIFYLDEEEEEDEEDCCCCCCCCCCFYFFFFFFFFFAAAAAAAAFYLYLYLYYYYGGGGGGGGGGAAAAAAAAAASTSTSTSSSS

ATAAASPSSANKNNNTKNTNEE-EEEEEEEYY-YYYYYYY---S------YN-YHHHHHHEE-EEEEEEEEE-EEEVEEEFF-FFFFFFFNN-NNNNNNNFF-FFFFFFFVA-VVAAAAVLM-LNMMMMNEE-ESEEEESII-ILIIIILQQ-QQQQQQQIVIIIIIIIIVVVVVVVVVVLLMLLLLLLLVVIVIVVVVIEEEEEHEHHEDEDDDDEDDDQEQQQEEEEQYYFFFYYYYFWWWRWWWWWWTTTTSTTTTSDDNEDDDDDDLTLLLTTTTLAASAAAAAAAGGGGGGGGGG--C-------SHRSRKHRKRTTTTTTKTTTPPPPPPPPPPEGEEEEGEEERGRRRRRRRRVIIVIIIYIIRRRKRKRKKR

EEEELFLEILFFFFFYFMFFKKKKRKKKRKVVVVVVIIVIDDDDDDDDDDLLLALLLALLKKKQKKKQKKKNNNNNDNNNSSSSSSASAAPPPPPPPPPPQHQQNQEQEEQKQQKRKQKKQQQQQQQQQQGAGGGGGGGGVVLVVVVVVVFFFFFFFFFFIIIIMIIIIIFFFFFFYFFYEEEEEEKEEEAAAVVVVAVVGGGGGGGGGGMVVVVVFVVIKMMIKKKVKKWWWWWWWWWWTQQTTTTTTTYLYYYYYYYYPPPPPSPPPPSGGGGGGGGGIIIIIIIIII------R-RR------A-AALIIILKLILLLFLLLTTLTTVIITVVVIVVLLLLLVLLLLAAAAAAAAAAFFFLFFFMFF-PS-------AAAAAAAPAASSSYSSTYSTHHHHNNNHNN--N---------Q-------

AVAVAAVVAAFLFLFFFLFFVVVVVVVVLVGGGGGGGGGGRKRKRRRKRRYWWWFWYWWWENENEENNEESCACAACCASTTTTTTTTTTYYFYYYYYYYGGGGGGGGGG-----H----LLLLLLLILLQQQQQGQQQQEEEEEEEEEECCCCCCCACCE-EEKVEEEEA-AASAAAAAQ-KEQQKEQQL-LLLLLLLITSATKATTTTWWWWWWWWWWAAAAAAAAAAEEEEEEEEEEKKKKGKKKKK-AFFFFYFF--KEKKETKG-DDDDDDDDDDLLLLIILLLLDDEDDDDDDDLLLLLLLLLECCTCCCCCCCIIVIVVIIVIKKKKKKKKKKAQAEAAEEAAEEEEEEEEEEYYYYYYYYYYRKRKKRKARRRKKKRKKKRRAASAAAAAAA-F-F---F--SPPPPPPPPPDGNGDSGGDD

PPPPPPPPPPASAAASASSAMMMVMQLQAMLMMLLLLLLMIILIIIIIILMMMMM-MMMMLLLLL-LLILMLLIL-IMLLEAAAA-AEAAMKKKK-KMKKEEEHD-NEEEAAAAA-AAAACHGCC-CLHCSPSTS-SNSSAVIII-IVVIVVVMVVVVVVVIMFIVIVIMAAAAAAWAAAIIIIIIIIIIRRRRRRLRRRRRRRRRRRRRQKRKRQKQKREEEEEEEEEEVNNNKTNTNNLLLLLLLLLLANDTTATATTRGRRRRRRRREEEEEQEQEEC-CCCVCVCCT----T-T--AAAATAAAAAEEEEEEEE-ELIIIIVVL-IFFFFFFFF-FRKRRRRRR-RAAAAAAAA-ARRRRRR-R-R

QQQQQQQQEQGGGGGGGGGGIVVSVVTTVVVVVVVVVVVTATAATTTTTTLQQQLLTTQLVVVVVVVVVVAAAAASSSAARRRRRRRRRRQQQYQQGQQQEEEEEEEEEKSSGGSSPPGSIIIIIIVVIISSAASSSSASGGGGGGGGGGTDSSTTTTATSTTTANTTTSAAAAAAAAAAMMVVMMMMMMSASSSSSSSSFFFFFMFFFFWWWWWWWWWWDEEEDEEEEEMLLLLLIILLCCCCCCCCACNGGGNNHHGNVLLLVLLLLLFFFFFFFFFFEEEEEEEEEETTTTTTTTTQVVVVVVAVVVVITMIIIIIIQGGGQSSSGQGGAGGGGGGGNNNNNNNNNNSSSSSSAASSKPPPTTTTPTVIIIVVVVIV

DDDDDDDDDDYYYYYYYYYYSSTASAKAATKKTTKTKKTTTSTTATSTTT--L------L--L------LNNNNNENNENRRRRRRRRRRAAAAAAAAAAFFFYFFFFFFHHHHHHHHHHYYYYYYYYYYFFFFFFFFFFTSAASATAAAPPPPPPPPPPDDDDDDDQDDFFFIFLFVLFNKDDHDNDDDNNNNNNNNNNLLLLLLLLLLGGGAGSGAGGYYYYYYYYYYFFFFFFFFFFPPPPPPPPPPVINVIVIVVNVVVVVVVVVVRRRQRKRQKRRRQRRRRRRR-DDDDDDDDDKNNNNNNNNNYFYYYYYYYYLLLILILIILVVVVVVVVVVRKKKKKKKKKDDEEDKDEKEFVFFIFIFHFWWWWYWWWWW-------V---------L---------E---------N--

GGGGGGGGGGLLLLLTLLLL------L---YFLYFFVYYYQQAQSQSQQQFFCFCFFFFFFFMFFFFIFFPPKPPPPPPPVVVVVVVVVVQQQQQQQQQQYYYYYYYYYYGGGGGGGGGGAAAAACAAAVRRRRRRRRRRCCTCCCCCCFSSSAEDSSDSSTATANAAASHQNTHHHHHHIIIIIIIIII-----Y---------N-----YHYRYHHHT-LMLMLAAAMEKKEKKKEEENGGGGGGGGNGGGGGGGGGGLLLLLLLLMLEEEEEEEEEEDQDQDQDDYDVVIVIVIVVVAAAAVAAAAVKKKKKAKKKNQQQQQQQQQQIILVIIVIVIIVFVFVVVIVCAQAESACSRLFYFYLYFYLVAAHAAAAAAVVVVVVVVVVHTSTSTSTSTASSAASAAAA

NENEKKKKKKLLLLLLLLLLPPPPPPPPPPIIIIIIIIIIEEEEDDDDDDSSSSFSSSSSDEDDNNNNNNDDDDDDDDDDNNNNNNNNNNFFFFFFFFFFAVVVTTTTAVVIVV-V--VVCSCS-S--SSNNSNSNNNNNILMLMMMMLLTTTTTTTTTTEEEEEEEEEEAAAAAAAAEEAPCPAAVAAAVVVVVVVVVVIVLIVVVVVVKKKKKKK-KPAGAGAAAAEEVVVVVVVVVVMMMMFFFFYFMLMLMMMMMMEEEEEEEEEELLLLLLLLLLFHFFYFYYFFVLIIVIVVIIDEDDDDDDDDFYFYVFFVYYQNHNHHHHHHTTTTSSDSTTSASAAAAAKAH-HHHHHHHHDSDSDDDDDD

MLMMMMMMLMGGGGGGGGGG-QSSSSSSGSHFFFFFHHFFRRRRRRRRRR-----D---------I---------D---------A---------R----EEEEAEQEEECCCCCCCLCCRRRKRRRRRKVVVVVVVVVVLFLLLLLLFIRRRRRRRRRRPPPPPPPPPRLMILLLTFMLHYYFYFHHYTTSAAAATTSVKQKQKQKKQQPPPPPPPPPATTTTTTTTTTILLLLLIILLLLLILLLLLLVVTVSVVVVVGGGGGGGGGGQHHHHHQHHHCCCFCCCCCCQQQQQQQRQQRRQRRRRRRRTPTTTTTTLTKKKKKKKKKKSSSSSSNSSSTTTTTTTTTTLLLLLLLLLLRSRRRRRRRRQQQQQQQQQQGGGGGGAAAGLLLLLLLLLLPPPPPPPPPPSTSSSISSTSLLLLLMLLLMAAAAAALLAATKTTTTTTKTMLMMMMMMMMEEEDEEEEEDQQQQQQRQQQYYYYHYYYYS

RRRRRRRRRRHHHHHQHHHHNNNNNNNNNNRRRRRRR-RKLLMLLLILLLLLLLLLLLLLGQSGGGGGGGEKKSSSKEEEGGGGGGGDGGDKKKKKKRKKNNSNNNNNNSEE-EEEESEEHH-HHHHHHHII-IIIIIIVYY-YYYYYYYPP-PPPPPPPRR-RRRRRTRLL-LLLLLLLRR-GGGRHHHKN-KKKKNNNEE-EEEEEEEGG-GGGGGGGII-IITIIIIVV-VVVTVVVKK-PPPKKKKKK-KKKKKKEWW-WWWWWWWKK-KRRKKKKFF-MMMFFFFSS-SSSSSSSPP-PPPPPPPSSSSSETSSSVAAAAAAVVVGGGGGGGSGGVVVVVYVVVVKNERRRRRRRGGGGGGGGGGTTASSSTSSS-VVVVVVIII-LLLLLLLLL-PPPPPPPPP-GGGGGGGGG-TETTTTTTT-VVVVVVVVV

SS-SSSS-NSKK-KKEK-KKEE-EEEP-NELL-LLLL-LLHHHRHRHHHR---P------SSKRSRSKKSDDDDDDDDED--EE-EEED---RK-RRRR---II-IIVI---ED-AEED---PP-PPPP-VVIVIVVIVLGGGGGGGGGGVVVIVIIVIVPPLLPLLLLPYYYYYYYYYYIIIMIMMIMIRQKKKQKKETMMMMMMMMMM--GA-AGGG---L----R----A----A--AAAAAASAAALIMIIIIMII-W-------W-T-------R-P-------P-I-------I-Q-------QLLQLLLLYLLEEEEEEEEKET-SSDNSSSTL-WWLWWWWLY-YYYYYFYYR-KRRRRRRRQHHHQHHHHHQQSQQGSRSQGNNNGNNDNNAAAAKAAPAAKKRRKRRRRRYYYILIYYIYLLLLLLLLLLVVVFVFFAFAIILIIIIFIIFYYFYFFYFY---E---------L---------K---------L------VVVVVVVVVVLLLLLLLLLLKKKKKKKKKKWWWWWWWWWWHHHTHHHHHHTTTSTTASTT

FFFFFFFFFFHQQQQQQQQHLLLLLHLLLLDEQQEQQQQDPPPPPPPPPPGGGGGGGGGGPPAPPAHAHPSSSNSSDSASKKPNKPKPKKQQQQQQTQQQEEDEEDEDEEEDDDDDDDDELLFLLFLFLL-L--L------E--E------A--A------N--T-----KENQQNQNQQNYHHHHHHHNNHNNCNNNNNMIVIIIMILMSS-SS-S-SSRR-KR-K-KRMI-II-I-IMYY-YY-L-YYPP-PP-P-PPVI-LI-I-LVPA-PP-P-PPDDEDDEDEDDRRRRRRKRKRIIVIIVIVIIQQGNQGNNRQTTTTTTETTTSSTSSTSTSSIIIIIIIIIIAAAVAAAAAAFFFFLFFFFFKKEPRKKKKK--H--H-H--SSAASAAAASDEQADQAQSDPPPPPPPPPPAAAAAAAMAASSSSSSSSSSFFFLFLFFFF

HHYHHHHHHHVVVVVVVVVVTRTRRRRRRRLLLLLLLLLLVVVVVVVVVVWWWLWWLWWWTTTSMMSMPMWWWWYYWWYYVVVVVVVVVVVVVVVVVVVAYYYYYYYYYYYYYYYYYYYYEEEEEEEEEE---T--S---EEEESEEESSESSSSDSSAAQQQ-QQQQQQEEE-AGEGAAKKK-RKKKRRRRR-RRRRRRVVV-VMVVVVYYY-YFYYFYLIL-LLLLLLLLL-LLLLLLEEE-EEEEDDIII-IIIIIIAAA-SAAASSFFF-FFFFFFSSS-SSSSSSKKE--TEPPPVVV--IIIIISSS--TSTTTQQW--QQQQQLLL--LLLLLAAA--FAAAAFFF--FIFFFYHYSYYHYYYVVIVVVAVVVHHEQFFQFFFFFFFLFFFLVNNNNGDNDGGTTTTATTTAAQQQQQQQQQQNNNKNNKNNNAAAAAAAAAA

-----DD--DTNNTNNTNNSDDNNNDDDDDDDGDDDDDDDFFFFFMFFFICCVLCCCCCCVVVVVVVLVVYYYYYYQYYKLLMMMITILTNNNNNNNNNNGGGGGGGGGGRRRRRRRHRRWVLLL--LV-KKKKK--KK-GGGGG--GG-GGGGG--GG-KQQQQ--TK-HRKKH--VH-FFFFF--FF-YY-YYYKYYYVV-AVVVVVLVV-IIVVVVVLLLLLLFLLFIIIII-MIIMTTTAT-STTSQQQQQ-IQQ-LLLLL-LLFLSSAAA-PPSPKKVVV-KKKKFFFFF-FFFFYYYYY-YYYYEKKKK-KKKKAATTT-VVAVKKKKR-KKKKWWWWW-WWWWEEEEE-EECEKKKKK-EKKEWWWWW-WWWWAAAAA-AFAAAAAAA-AAAAHHHHH-HHHHNNNNN-SSNSNNNNN-NNNNDDDDDDDDDDYFFFFFFFFF

LLLLLLMLLITTTTTTTTTTNDCNNNNDSNILIIVIMLIVAAAAYAAAAAGGGGGGGGGGNSSSSSNSASHHHHHYHHHHFIFFFFFIFIDDDDDDEDDDGGGGGGGGGGGGGGGGGGGGTTTITTTVTTGSGGGGGSGS---D--D------T--T------Q--Q------A--A---LILIIIIILIWWWWWWWWWWEAEDEEEEEEEEEEEEEEEEQKQQQQQKQAKKKKKKKKKKKKTRKKRKTKPPPPPPPPPPPPPPPPPPPPDDNDDDDDDDPPPPPPPPPPPPTPPLPPPPLLLLLLLLLLYYYYYYYYYYIVVL--MVVVAKAK--SKAELLLL--LLLLSSSS--SSSSAAAA--AAAA

IIIIIIIIIIVVVIIIIVIVSSSTSTSSTSVVVVVVVVVVQQAQQQQQQAKKKKKKKKTKSTASSSTSSAPPPPPPPPPPTTVATRATRTAAAAVAAAAAKEEKKKKKKERRRRRRRRRRLLLFLFFLFLRRRRRRRRRRLLLLLILLLLKKKKKKKKKKKKRKKKKKKRLLLIALLLLLLLLLLLLLLLFFFFFFFFFFTVVYTYTTYVFFFFFFFFFFSSSSSSSSSSRRRRRRRRRRLLLLLLLLLLEEEEEEEEEELI-LILLILIDD-NDDDDDDIIIIIIIIIIEEEEEEAEEELVVLIILIVIAAAMAAAAAAKKKKKKKKKKIIIVIA-IVIIVVVVLVVLVAAAAAAAAAADDDDDDDDED

PPPPPPPPEPVAVVVVVIVVRRRQRRRRRRVVVVVVVVVVTATTTTTATTQEQQQQQEEQFFFFFFFIFFQKQQQQQRRQGGGGGGGGGGPPPPPPPPPPRKRRRRQKRQVVVVVLVVVIRRRLLRARRGYYYYYYYYYFLLLLLLLLLLEEEEEEEEEEVVVVVVVVVVEEEEEEEEEELLLLLLLLLLEEEECEAEEELTTTTTTTTTIVIIIIIVVIVVVAAVVVVVSTSSSSTTTTQQQQKQQQQQTNTKKKKSRKPDPDDDEDDELLLLLLVLFVPSSSSSSSSSNR-RRNRRRRII-MIIMIIMKQ-QKKQQQQSS-SSSSSSSAA-AAASAAAGA-GGGGAAGVV-VVVVVVVRK-KKRKKKKTT-TTASTTSQQ-RRQQQQQPP-PPQPPPP

DDDDDDDDDDYYYYYYYYMYQQQQQQQERQRRKRARRRRRQQQQQEQQQQQKKQKKKKQKLLLLLLLLLLFYFFFFYFFFEEEDEEEEDEIVVVSTVVVIGGGGGGGGGGGGGGGGGGGGEEEDEEEEEEVVIIV-VVIITTTTT-TTITRRKKK-KRKKQEEREEESQENNHSNNNHNNTTTTTTTSNTLRLLLIRLLLFFFYFFFFFFSAEEEEADTEVVVVVIVVVVRRRRRRRRRRTSTTKKSTSTIILIIIIIIIMEEQEEEEEENNNDTTKNNNLYYLYYYYYYIIIIVVIIIILLLLLLLL-LVVVVVVVIVVLLLLLLLLLLVVVVVVVVVVAAAAAAGAAAAAAAAAAAAALVSTAVVTTTRDKRDDDQRKQDEEDHDEEERNNNSANNNNTATTTTTTTTVVVVVVVVVV---------S---------T---------I---------F---------K---------R---------K---------QVVVVAVVVVV

LFLLLL--L-EEEEEE--E-VYVVVV--I-MMMLMM--L-GRGGRG--C-DDDEDD--E-LLLLLL--L-EQQRQE--Q-GGNNAG--N-SASSSS--A-ILIIIIIIIFEKEAEEEEEESSSSSSSSSTFFFFFFFYFFSSSSSSSSSSRQRRQRHRRRSSSSSSAGSGLLLLLLFFFFYYYYFYYYYYTTTTTTAATAIMIIMIIIIIGGGGGGGGGGTITTITTTNTFFFFFFFFFFYYHHYYHHHHNSNNSNNSNNDDDDDDEEEENNNNNNTSNTTTTTTTTTATPPPPPPPPPPHHHLHHLLLL-----K---------L---------Q---------E---------E---------H---------M---------R---------E----QQQQQQEQQQCCCCCCCCCCGNGGNGASAAQVQQIQQQQQSSSYSSS-SSLLMLLLV--FIIMIIIV-VVRRRRRRR-RR-----W----

AAAAAAAAAADDDDDDDADDGGGGGGGSGGFFFFLFFLFFGGGGGGGGGGNNNNNNNNHHEEEEEEEEEEGKKGPGGPPPRRQRRRRRRRIIIIVVVLVVDNNNRNNRRRK-KKKKKKRRA-AAAAAASSQ-QQRQQRR-R-NRNRRNNNI-VII-IILTLLMLLLLLLLEEEEEEEEDEIIIVVVVIIIVIILIVVIIILLLFLLLILLDDDDDDDDDDD---------RRRRRDRRRRTTTTTTTTTTGGGGGGGGGGLLLLLLLLMLTTTATTTTTTFFFFFFFFFFFMMFFFFMFFAAAAASSSAATTAATTSTTTRRRRRRRRRRFTIFFFFFFF

EEEEEEEEEEQITITTIITIQQQQQQQQQQPAPPPPAPPPIITIITIIII---------H---------FANANAANANNMNNNNQNNNNDDDDDDDDDD-------M---------K---------E---------T---------R---------S---------N---------N---------I---------I---------S---------S--CCCCCCCCCCDDDDDDDDDDGGGGG-GGGGHHHHH-HNHHGGGGG-GGGGAAAAA-AAAADDDDD-DDDDIILVI-IIIVDDDDDDDDDDQEKKKKEKKKAATAAAAAEAPPPPPPPLPPYYYYYYYYYYAAAAAAAAALAVAAPAAAAAVVVVVVEVVV-------V---------T--SSSSSSSSSSEGGGGGGGGGFIFFFFIFFI--H--H----WWWWWMWW-WTTSTATTTTTFFFFFFFFFLHHHHHHHHHHYRYRYYRRRRIIIIIIIIII---T---------S---------P---------F---------E---------C------AAAAAAAAAALLLLLLLLLLGGGGGGGGGGNNNNKNNDNNLLILLILLLLPPPPPPPPPPEEEEEEEEEEKKKKKKKKKKNNNNSNNNNN

IIIIIIIVII---N---------S---------W---------V---------L---------L---------E---------E---------I---------C---------I---------R------VVVVVVVVVVEDDEEEDESEEKKEEEKEEEKKKKKKKRKKPAPPPPPPPPKRRKKKKKKKPPPPPPPPPPASSAGAAAAAATTQQATAAARRRRRRRRRGRRRRRRRRRR------T---SSSSSSSSSSQQQQQQHQQQVVVVVVVVVVEEDEAEEEEERPPRRRPRRSDDDDDDDDDDRRRRRRRRRRDDDDDDEKDDEEDEEEEEEEEDDEEEDEEELLLGGLLRLLDDDDDDDDDDFFFFLFFFFFRRRRRRRRRRQQKQQHQQQQWWWWWWWWWWSSSSRTSSTSEDDEEEDEEETTTTTTTTTTAAAAADAADAGDSNNDNNDNDEEDDDDDDDRRRRRRRRRSPPPPPPPPPP-----L--L------S--T------H--H------V--V------M--M------V--V-LLLLLPLIPLVTTTTQTTTTVEQKRIEVIKTITTTTTTTTYYYYYYYYYY---EK--------AA-----

IIVVIIVVIIDDDDNDDDDDNNGNYGNNNNVVVVVVVVVVIIMTILLLIIIIIIIIVIIVFLLLLLLLLLWWWWWWWWWWTTTTTTTTTT-LLLLLLLLL----T---T-----N---N-----I---V-----N---N-----A---A-----I---I-----Y---Y-----T---T-----W---W-----V---V-----T---T-----Y---Y--KKKKKKKKG-GGGGGGGGG-DDDDDDDDD-CCCCCCCCC-SCCYCCCCC----I---------V---------F---------R---------F---------I---------T---------T---------E---------R-----KKKKKKKKKHCCC-SCSSCCLLLLLLLLLLGGGGGGGGGGNNNNNNNGNNAARSAASSAADDDDDDDDDD---G------SSSASSSASSVVVAVVAAVVDDD-NDD-TDIVIIVIIIVIAGGGGGNQGG---D--DD-----I--IV-----I--II-----D--DD-----S--SS-----T--TT--ILIIIVIIIVTTTVRSTTTTFFFFFFFFFF----N---N-----E---E-KKKKKEKKKKAAAAAAAVAAVAVVVVVVVVPPPPPPPPPPQQQQQQQQQQILFILLLVLLHHHHHHHHHHGGGEGGGGGGVLVLPLLLPIGRGGKGGGRREEKEEDEEEERQQQQQQQQQ

YGAGPGGGGGKKKKKKMMKKLIIIIIIIIIIIIIEIIIIILLLLLLIILLVIIVVIIVVVQQKQQKKKQQTTTETTTTTTTTSTKSSSTTKKKKKKKKKKGGGGAGGGGGGGGGGGGGGGNTSTTSQQSTYYYYYYYYYYLLLLLLLLLLTSSRESSSSKAAAAAAAAAAIIIIVIVAIINNHNNNNNNNHRSHHRRQHHTTTTTETTTTDNDNDNNNNNDDDDDDDDDDGGQNGQQQGAGGGGGGGGGGGGAGGAAAGGYYAGYAAAYGLLLLLLLLLLKKKKKKKKKKVVVVVVVVVIVVVVVVIIVVSAAASAAAAARRRRRRRRRR

VIVIVVVIIV-FFFFFFFFF-GGGGGGGGGSSSSSSSASSPPPPPPPPPPAGGGGGGGGGYYYYYYYYIYSTT-TTT-SSYYY-YYD-YYLLLLLLLILLVVVTVVVVVVIVPIIIIIIFTNNNTTTNTTSSSSSSSNSSFLLLFFFLFFRKKKRRRKRRAAAAAAAAAASQQSSSASTSDDDDDDDDDDHQEQQQRQQQFYY-YYY-YY----KKE---LHD-QQH-HHKNN-KKR-KKKKK-KKK-KRRRR-RKR-RRGGG-GGG-GGEEE-EEE-EELLL-QQQ-LLFFFFFFFFFLLLLLQLLLLLGGGGGGGGGGRRRRRRRRRRLMLLLLLLLLNEETKQRTRNTTITTTTVTTLLLLLLLLLLDDDDDDDDDDNPPPQQQPQTGGGGGGGGGGS--SSSSSSSP--PPPPPPP

TTTTTTTVTTVVIIIIVIIICCCCCCCCCCAAAAAACAAALLLMLMVLMLIVIIVIVVIIIMIMMMFMMINDNNDKDNNNSSSSSSSSSDGGGGGGGGGGSSSPSSSSASEEEEEEEAEEVETEEDEEDTGGGGGGGGGGSSGSSSSSDSVVI-V-VV-VAAS-A-AA-AAAA-A-AA-ATTT-T-ST-THNH-N-TN-HIII-I-II-ICVCCVLVCACPP-SPSPPP-AAAPAPAAPAMMSMMMMMMSGGGGGGGGGGKEGKEKEKKGTTTTTTTTTTPVPSVTVIVPRRKRRRRRRRLVLLLLLLLLPPPPPPPPPPKKKKKKKKKLLILLILILLRPPPPPPPPPPGGGGGGGSGGRKK-K-KK-KTVVVVVVIVVDDDDDDDDDDTTTTTTTTTTEEPEEEEEEPTDETTVTTTTNNNLNLNNLNAPAGPAAAAAMMMMVMMMMMRRRRRRRRRRYHHHHHHHHHIVVVVVVVVVNNNKNSNNNN

FFFFFFFFFFGSKKSGSSKSPRPPPPPPPPGGGGGGGG-GDDDDGDDGDGFFSFFFFFFFEEEEEEEEEECCCCACCKCCSSSSSSSTSDDDDDDDDDDDEEEEEEEEEEPPPPPPPPPPKKKKKKKKKKAAAAAAAALADDDDDDDDDDQQQQKQQQQQLLLLLLLLLKPPPPPPPPPPRRRRRRRRRRRVRRIRVVRITTSSTTTTMTYYYY-YY-Y-AAAA-AA-A-IMII-IM-I-LSLL-LS-L-FFFF-FF-F-RKKK-RK-K-KKKK-KK-K-------G---IIII-IV-I-RKRRKRKKRKLLLLLLLLLLLLFFFFLFFFRRRRRRRRRRVVVVVVVV-VFLFFFFFFFFSTSSTSTTSTQQMMQQQQMEASSSKASKSPLLLLLLLLLLEEEEEEEEEELLLLLLLLLLPPPPPPPPPP

--D-D-------S-A-------R-R---------Q-------P-P-------T-A-------E-K-------V-V-------S-T-------T-T-----HQHHYNHHHHAATAAAAAAA-----W---------C---------L---------S---------V---------R---------E---------E---------G---------D---------L----LLLLLLLLLL--L---------T---------K---------C---------T---------Y---------G---------R---------L-------TATSTSSTSTAAAAAAAAVACCCCCCCCCCVVVVVVVIVGMFMMLMMMMMAAAAAAEAEAII-TITTITIFFFFFFFFFFRMMMTLMMMMCCTTTTTCTTHHHNHNNHHNFFFLFMLLLLQQTQQQQQQQLLLHLQQLQLDDDDDDDDDDDDDDDKTDTDVVVVVVVVVVAAAAASAAAATVILIIITIIGGAALSSGSGWYYRYRRWRRQQQQRDTQQQNNNNGNNNNNDDNDNDDDDDCCCCCCCCTSEEEEEEEEEE