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2. ROSA PSA medial parapetallar approach
3. ROSA PSA medial subvastus approach Participants will be followed for 1 year post surgery with a combination of perioperative parameters, imaging, patient reported outcomes, functional outcomes, blood and tissue sampling for inflammatory information and activity levels. conditions: Knee Osteoarthritis studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEARCH masking: NONE count: 90 type: ESTIMATED name: ROSA PSA Parapatellar Approach name: ROSA PSA Subvastus Approach measure: Functional Outcome - Weight-bearing CT scan measure: Functional Outcome - 3D Ultrasound measure: Functional Outcome - Timed Up and Go test measure: Patient health status - Knee Society Score measure: Patient health status - EuroQuol Survey measure: Patient health status - Knee Injury and Osteoarthritis Outcome Score measure: Patient health status - Western Ontario and McMaster Universities Arthritis Index measure: Patient health status - Global Assessment measure: Health Ecominics sex: ALL minimumAge: 21 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University Hospital status: RECRUITING city: London state: Ontario country: Canada lat: 42.98339 lon: -81.23304 hasResults: False
<|newrecord|> nctId: NCT06267469 id: Boutonniere deformity briefTitle: Boutonniere Deformity Effectiveness of Thermoplastic and Fabricated Orthoses overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2024-09-30 date: 2024-09-30 date: 2024-02-20 date: 2024-02-20 name: Magdalena Kolasińska class: OTHER name: National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland briefSummary: The goal of this study is to present the author's thumb orthosis with a butonier deformity and its effect on hand function, strength, dexterity and pain levels in relation to patients wearing factory-made orthopedic supplies. It is planned to include about 60 people in the study (30 people each in the group with thermoplastic orthoses and 30 participants with factory-made orthoses)
The main questions it aims to answer are:
1. How much improvement in dexterity will the patient wearing the orthosis get? 2. By how much will the grip strength of the whole hand and pincer grip strength improve with the orthosis? 3. How will wearing the orthosis affect the pain associated with the disease? Participants will
1. measurement of grip strength of the right and left hands with a dynamometer in an orthosis and without an orthosis, at the time of the test conducted and at the appointed times.
2. measurement of pincer grip strength with a dynamometer in an orthosis and without an orthosis, at the time of the test conducted and at the designated times.
4. completion of the DASH questionnaire 6. assessment of the NRS pain scale in relation to the period of 6 months before the start of the study 7. Likert scale - evaluation of satisfaction with the use of the orthosis 8. the Kapandji scale Researchers will compare patients with thermoplastic orthosis and patients with fabric orthosis to see which is more functional. conditions: Orthotic Devices studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 60 type: ESTIMATED name: Thermoplastic orthosis measure: Grip strength measure: DASH -Disabilities of the Arm, Shoulder and Hand measure: Likert scale measure: Kapandji score measure: NRS - Numerical Rating Scale measure: pinch strength sex: FEMALE minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji im. prof. dr hab. med. Eleonory Reicher city: Warsaw state: Mazowieckie zip: 02-637 country: Poland name: Magdalena Kolasińska, Msc role: CONTACT phone: +48609219822 email: [email protected] name: Teresa Sadura-Sieklucka, Phd role: CONTACT email: [email protected] lat: 52.22977 lon: 21.01178 facility: Terapia Ręki Magda Kolasińska city: Warszawa state: Mazowieckie zip: 01-494 country: Poland name: Magdalena Kolasińska, Msc role: CONTACT phone: +48609219822 email: [email protected] lat: 52.22977 lon: 21.01178 hasResults: False
<|newrecord|> nctId: NCT06267456 id: HÜ- FTR- BD- 01 briefTitle: The Reliability of ULRT in Overhead Athletes and Its Relationship With Selected UEPT overallStatus: COMPLETED date: 2022-01-01 date: 2023-01-01 date: 2023-01-10 date: 2024-02-20 date: 2024-02-28 name: Hacettepe University class: OTHER briefSummary: Upper Extremity Rotation Test is a new test the evaluates 90-90 position, which is one of the requirements for overhead throwing. The aim of the study was to evaluate the reliability of the Upper Extremity Rotation Test in overhead athletes and the relationship between the Closed Chain Upper Extremity Stability Test and the Upper Quarter Y Balance Test. conditions: Upper Limb Asymmetry studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: handball, volleyball and basketball players 18-30 years Someone who has been participating in sports for at least three years and trains at least three times a week primaryPurpose: DIAGNOSTIC masking: NONE count: 48 type: ACTUAL name: Upper Limb Rotation Test name: Closed Kinetic Chain Upper Extremity Stability Test name: Upper Quarter Y Balance Test measure: The reliability of Upper Extremity Rotation Test measure: The Relationship Assessment of the Upper Extremity Rotation Test sex: ALL minimumAge: 18 Years maximumAge: 35 Years stdAges: ADULT facility: Birgül Dıngırdan city: Kocaeli state: İzmit country: Turkey lat: 39.62497 lon: 27.51145 facility: Hacettepe University city: Ankara country: Turkey lat: 39.91987 lon: 32.85427 hasResults: False
<|newrecord|> nctId: NCT06267443 id: 2023/337 briefTitle: Erector Spina Block or Parasternal Block Plus Chest Tube Wound Infiltration for Cardiac Surgeries overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-07-01 date: 2024-08-01 date: 2024-02-20 date: 2024-02-20 name: TC Erciyes University class: OTHER briefSummary: Pain management is important after coronary artery bypass graft (CABG) surgery. Intravenous morphine is the gold standard for pain relief, but its sedation, cough suppression and decreased bowel movements limit its use. Analgesia with regional methods after surgery provides effective analgesia by reducing morphine consumption. In this study we have planned to compare the erector spina plane block with parasternal block +local infiltration to chest tube areas. conditions: Postoperative Pain conditions: Postoperative Atelectasis conditions: Analgesia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 100 type: ESTIMATED name: Comparison of erector spina plane block, parasternal block plus local infiltration to the tube sides for postoperative analgesia measure: postoperative analgesia measure: postoperative atelectasia measure: postoperative mechanical ventilation duration sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
<|newrecord|> nctId: NCT06267430 id: NL85141.078.23 briefTitle: Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD acronym: LbH overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-12-31 date: 2027-04-30 date: 2024-02-20 date: 2024-02-20 name: Erasmus Medical Center class: OTHER briefSummary: Advances in prenatal and neonatal care have improved outcomes in children with severe congenital heart disease (CHD). With the increase in survival, neurocognitive problems such as executive functioning (EF) impairments have become more apparent in these children. EF problems have cascading negative effects on a child's development. New insights in EF development suggest that in otherwise physically healthy young children, EF can be improved by training. In a pilot study funded by Stichting Hartekind, the investigators studied the feasibility of a personalized EF training program called 'Kleuter Extra' and the results were promising. Therefore, the current study will investigate the effectiveness of this program in 4-6-year-old children with severe CHD. The researchers will also explore interactions between the parent-child relationship and EF development of the child as psychosocial difficulties in these children and their parent(s) and/or caretaker(s) may impact EF-development. If found effective, EF training for children with severe CHD will improve their developmental outcome. conditions: Congenital Heart Disease conditions: Executive Dysfunction conditions: Attention Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: SINGLE maskingDescription: The psychologist testing all participants, will be blinded for the allocation of the participants. whoMasked: INVESTIGATOR count: 141 type: ESTIMATED name: Kleuter Extra training program measure: Kleuter Extra test battery measure: EF functioning measure: Information processing measure: Executive functioning in daily life - completed by the parent(s) measure: Behavioral and emotional difficulties of the child - completed by the parent(s) measure: Quality of the child's life - completed by the parent(s) measure: Emotional distress parent - completed by the parent(s) measure: Parental trauma measure: Parenting behavior and quality parent-child relationship - completed by the parent(s) measure: Child demographics teacher's perspective measure: Behavioral and emotional difficulties teacher's perspective measure: Executive functioning child in daily life teacher's perspective sex: ALL minimumAge: 4 Years maximumAge: 6 Years stdAges: CHILD facility: University Medical Center - Beatrix children's hospital Groningen city: Groningen zip: 9713GZ country: Netherlands name: Hessel Nijenhuis role: CONTACT email: [email protected] lat: 53.21917 lon: 6.56667 facility: Erasmus Medical Center Sophia Children's Hospital city: Rotterdam zip: 3015CN country: Netherlands name: André Rietman role: CONTACT email: [email protected] lat: 51.9225 lon: 4.47917 facility: University Medical Center - Wilhelmina children's hospital Utrecht city: Utrecht zip: 3584EA country: Netherlands name: Hans Breur role: CONTACT phone: +31 88 75 754 59 email: [email protected] lat: 52.09083 lon: 5.12222 hasResults: False
<|newrecord|> nctId: NCT06267417 id: CCHE-AML-4/2023 briefTitle: Laser Therapy Effect as Preventive Measure for Oral Mucositis in Children With Hematological Malignancies overallStatus: RECRUITING date: 2023-04-10 date: 2024-04-01 date: 2024-12-31 date: 2024-02-20 date: 2024-02-20 name: Children's Cancer Hospital Egypt 57357 class: OTHER briefSummary: Introduction:
Among the most drastic complications of chemotherapy is oral mucositis(OM). It is a painful inflammatory, often ulcerative condition and may increase risk for systemic infections leading to prolonged hospital stays and interruptions of treatment protocol. Many treatment modalities have been introduced for the prevention and treatment of oral mucositis , of which low level laser therapy(LLLT) is gaining popularity. The use of LLLT as a prophylactic treatment for chemotherapy induced oral mucositis in pediatric cancer patients is still lacking robust evidence. Also, the parameters used have not been optimized and no standard method has yet been established. Based on this point, this study will compare photobiomodulation to the conventional preventive program of oral mucositis applied in 57357 children's cancer hospital foundation to determine which will be optimal for the prophylaxis of chemotherapy-induced OM.
Aim:
To assess the effectiveness of low level laser therapy in the prophylaxis of oral mucositis in pediatric patients diagnosed with Hematological cancers.
Methods:
This study is a randomized, prospective, double-blinded trial that will include acute Myeloid leukemia patients admitted to receive chemotherapy cycle between the age of 3 and 18years. These patients will be randomized into two groups: group 1 will receive low level laser therapy and group 2 will receive mock treatment. Patient will be followed to asses the development of oral mucositis on prespecified time points. conditions: Oral Mucositis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: DOUBLE maskingDescription: The outcome evaluator will be a single personnel from the oncology team following up with the case whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 42 type: ESTIMATED name: Laser therapy name: Mock treatment measure: To measure incidence of oral mucositis in Laser arm versus Placebo arm. measure: To measure grade of oral mucositis in patients receiving laser arm placebo arm. sex: ALL minimumAge: 3 Years maximumAge: 18 Years stdAges: CHILD stdAges: ADULT facility: Children Cancer Hospital 57357 status: RECRUITING city: Cairo zip: 11617 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
<|newrecord|> nctId: NCT06267404 id: IShamsi briefTitle: Effectiveness of Iliopsoas Positional Release Versus Conventional Exercises in the Management of Sub-acute Back Pain. overallStatus: RECRUITING date: 2024-02-21 date: 2025-02-15 date: 2025-02-25 date: 2024-02-20 date: 2024-02-22 name: University of Karachi class: OTHER name: Sindh Institute of Physical Medicine and Rehabilitation briefSummary: Recommended treatment for chronic non-specific LBP is exercise therapy, behavioral therapy including pain management, or a combination of these; There is not enough evidence to establish recommendations for which one is the most appropriate.
The primary objective of this study is to explore the effects of Ilio-psoas Release on Sub-acute back pain, ROM \& functional disability conditions: Back Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 100 type: ESTIMATED name: Iliopsoas Positional release therapy name: Conventional exercises measure: VAS Visual Analogue Scale VAS Visual Analogue Scale measure: Modified Schober's test measure: Roland-Morris Disability Questionnaire sex: ALL minimumAge: 18 Years maximumAge: 40 Years stdAges: ADULT facility: Sindh Institute of Physical Medicine and Rehabilitation status: RECRUITING city: Karachi state: Sindh country: Pakistan name: Iram I Shamsi, MPhil role: CONTACT name: Iram I Shamsi, MPhil role: PRINCIPAL_INVESTIGATOR lat: 24.8608 lon: 67.0104 hasResults: False
<|newrecord|> nctId: NCT06267391 id: 898 briefTitle: Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes acronym: ReCET overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-01 date: 2026-10-01 date: 2024-02-20 date: 2024-02-20 name: Endogenex, Inc. class: INDUSTRY briefSummary: This study is designed to evaluate the safety and effectiveness of endoscopic intestinal re-cellularization therapy in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering medications. conditions: Type 2 Diabetes Mellitus conditions: Type2diabetes conditions: Diabetes Mellitus, Type 2 conditions: Diabetes conditions: Type 2 Diabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: The participants randomized in a 2:1 ratio to the ReCET treatment arm or the sham control arm. primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 264 type: ESTIMATED name: ReCET Treatment name: Sham Procedure measure: HbA1c measure: HbA1c measure: HbA1c ≤7.0% without requiring rescue medication measure: Time-in Range (TIR) measure: Total body weight loss (%TBWL) measure: Incidence of adverse events sex: ALL minimumAge: 22 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
<|newrecord|> nctId: NCT06267378 id: 1174/2022/NCTS briefTitle: Assessing Frailty and Its Impacts on Patients Facing Major GI Surgery overallStatus: RECRUITING date: 2023-08-30 date: 2024-12-01 date: 2029-12-01 date: 2024-02-20 date: 2024-02-20 name: Doncaster And Bassetlaw Hospitals NHS Foundation Trust class: OTHER briefSummary: The study team will look at 3 new tests that will make it easier to measure frailty in patients awaiting surgery for cancer and compare them against standard clinical measures of frailty in a pilot study. The expected outcome is that evidence will be collated in order to apply for a major grant to look at improving the care of frail patients with cancer in the future. conditions: Bowel Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Frailty measure measure: The sensitivity & specificity of digital motion data for the prediction of baseline clinical frailty levels & post-operative measures of frailty, mortality and adverse events measure: The sensitivity & specificity of tissue senescence for the prediction of baseline clinical frailty levels & post-operative measures of frailty, mortality and adverse events measure: The sensitivity & specificity of blood based biomarkers for the prediction of baseline clinical frailty levels & post-operative measures of frailty, mortality and adverse events measure: Blood biomarker correlation (baseline and post operative) with baseline frailty and poor outcomes (including length of stay and adverse events) measure: Adverse events related to surgery assessed CTCAE classifications measure: Tissue senescence correlation between baseline frailty and poor outcomes (including length of stay and adverse events) measure: Digital mobility outcomes correlation with baseline frailty and poor outcomes (including length of stay and adverse events) measure: Physical function assessment after surgery at 6 weeks, 3 months using the WHO DAS 2.0. measure: Quality of life at 6 weeks, 3 months after surgery using the EQ-5D-5L measure: Overall survival at 3 months and 5 years (the latter via cancer registry returns) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust status: RECRUITING city: Doncaster state: South Yorkshire zip: DN2 5LT country: United Kingdom name: Doncaster Royal Infirmary role: CONTACT email: [email protected] lat: 53.52285 lon: -1.13116 hasResults: False
<|newrecord|> nctId: NCT06267365 id: 23-00766 briefTitle: Predictive Biomarker for Endoscopic Therapy in Chronic Pancreatitis overallStatus: RECRUITING date: 2023-11-27 date: 2025-06-01 date: 2025-09-01 date: 2024-02-20 date: 2024-02-20 name: NYU Langone Health class: OTHER name: National Institute of Neurological Disorders and Stroke (NINDS) briefSummary: This is an observational prospective study to develop predictive biomarkers for pain response in participants with chronic pancreatitis scheduled for endoscopic therapy. Participants will undergo baseline assessments including electroencephalography (EEG), quantitative sensory testing (QST), and psychosocial questionnaires. Response to endoscopic therapy will be assessed at approximately 3, 6, 12 and 18 months post-procedure using questionnaires. conditions: Chronic Pancreatitis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: Change from Baseline in Brief Pain Inventory (BPI) Score at Month 3 Post-Operation measure: Change from Baseline in BPI Score at Month 6 Post-Operation measure: Change from Baseline in BPI Score at Month 12 Post-Operation measure: Change from Baseline in BPI Score at Month 18 Post-Operation measure: Change from Baseline in Patient Reported Outcome System (PROMIS) - Physical Function - Short Form 6b Score at Month 3 Post-Operation measure: Change from Baseline in PROMIS - Physical Function - Short Form 6b Score at Month 6 Post-Operation measure: Change from Baseline in PROMIS - Physical Function - Short Form 6b Score at Month 12 Post-Operation measure: Change from Baseline in PROMIS - Physical Function - Short Form 6b Score at Month 18 Post-Operation measure: Number of Participants who use Opioids at Baseline measure: Number of Participants who use Opioids at Month 3 measure: Number of Participants who use Opioids at Month 6 measure: Number of Participants who use Opioids at Month 12 measure: Number of Participants who use Opioids at Month 18 measure: Change from Baseline in PROMIS - Depression - Short Form 4a Score at Month 3 Post-Procedure measure: Change from Baseline in PROMIS - Depression - Short Form 4a Score at Month 6 Post-Procedure measure: Change from Baseline in PROMIS - Depression - Short Form 4a Score at Month 12 Post-Procedure measure: Change from Baseline in PROMIS - Depression - Short Form 4a Score at Month 18 Post-Procedure measure: Change from Baseline in PROMIS - Anxiety- Short Form 4a Score at Month 3 Post-Procedure measure: Change from Baseline in PROMIS - Anxiety- Short Form 4a Score at Month 6 Post-Procedure measure: Change from Baseline in PROMIS - Anxiety- Short Form 4a Score at Month 12 Post-Procedure measure: Change from Baseline in PROMIS - Anxiety- Short Form 4a Score at Month 18 Post-Procedure measure: Change from Baseline in PROMIS - Neuropathic Pain Quality 5a Score at Month 3 Post-Procedure measure: Change from Baseline in PROMIS - Neuropathic Pain Quality 5a Score at Month 6 Post-Procedure measure: Change from Baseline in PROMIS - Neuropathic Pain Quality 5a Score at Month 12 Post-Procedure measure: Change from Baseline in PROMIS - Neuropathic Pain Quality 5a Score at Month 18 Post-Procedure measure: Change from Baseline in PROMIS - Sleep Disturbance - Short Form 6a Score at Month 3 Post-Procedure measure: Change from Baseline in PROMIS - Sleep Disturbance - Short Form 6a Score at Month 6 Post-Procedure measure: Change from Baseline in PROMIS - Sleep Disturbance - Short Form 6a Score at Month 12 Post-Procedure measure: Change from Baseline in PROMIS - Sleep Disturbance - Short Form 6a Score at Month 18 Post-Procedure measure: Change from Baseline in PROMIS - Fatigue - Short Form 6a Score at Month 3 Post-Procedure measure: Change from Baseline in PROMIS - Fatigue - Short Form 6a Score at Month 6 Post-Procedure measure: Change from Baseline in PROMIS - Fatigue - Short Form 6a Score at Month 12 Post-Procedure measure: Change from Baseline in PROMIS - Fatigue - Short Form 6a Score at Month 18 Post-Procedure measure: Change from Baseline in Pain Catastrophizing Scale (PCS) Score at Month 3 Post-Procedure measure: Change from Baseline in PCS Score at Month 6 Post-Procedure measure: Change from Baseline in PCS Score at Month 12 Post-Procedure measure: Change from Baseline in PCS Score at Month 18 Post-Procedure measure: Change from Baseline in Sleep Duration at Month 3 Post-Procedure measure: Change from Baseline in Sleep Duration at Month 6 Post-Procedure measure: Change from Baseline in Sleep Duration at Month 12 Post-Procedure measure: Change from Baseline in Sleep Duration at Month 18 Post-Procedure measure: Change from Baseline in Tobacco, Alcohol, Prescription medications, and other Substance (TAPS) Score at Month 3 Post-Procedure measure: Change from Baseline in TAPS Score at Month 6 Post-Procedure measure: Change from Baseline in TAPS Score at Month 12 Post-Procedure measure: Change from Baseline in TAPS Score at Month 18 Post-Procedure measure: Change from Baseline in Patient Global Impression of Change (PGIC) Score at Month 3 Post-Procedure measure: Change from Baseline in PGIC Score at Month 6 Post-Procedure measure: Change from Baseline in PGIC Score at Month 12 Post-Procedure measure: Change from Baseline in PGIC Score at Month 18 Post-Procedure measure: Change from Baseline in Patient Health Questionnaire-2 (PHQ-2) Score at Month 3 Post-Procedure measure: Change from Baseline in PHQ-2 Score at Month 6 Post-Procedure measure: Change from Baseline in PHQ-2 Score at Month 12 Post-Procedure measure: Change from Baseline in PHQ-2 Score at Month 18 Post-Procedure measure: Change from Baseline in Generalized Anxiety Disorder 2 (GAD-2) Score at Month 3 Post-Procedure measure: Change from Baseline in GAD-2 Score at Month 6 Post-Procedure measure: Change from Baseline in GAD-2 Score at Month 12 Post-Procedure measure: Change from Baseline in GAD-2 Score at Month 18 Post-Procedure measure: Change from Baseline in Pain, Enjoyment of Life and General Activity (PEG) Scale at Month 3 Post-Procedure measure: Change from Baseline in PEG Scale at Month 6 Post-Procedure measure: Change from Baseline in PEG Scale at Month 12 Post-Procedure measure: Change from Baseline in PEG Scale at Month 18 Post-Procedure sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: NYU Langone Health status: RECRUITING city: New York state: New York zip: 10016 country: United States lat: 40.71427 lon: -74.00597 hasResults: False
<|newrecord|> nctId: NCT06267352 id: 230097 briefTitle: Epidemiology and Genomic Surveillance of Staphylococcus Aureus in ICU Neonatology acronym: NEOSAUR overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2026-06 date: 2024-02-20 date: 2024-02-20 name: University Hospital, Caen class: OTHER briefSummary: Newborns hospitalized in Neonatology are particularly vulnerable to infections, in particular healthcare associated infection (HAI). Staphylococcus aureus represents the 2nd microorganism responsible for sepsis, this infection is particularly serious and like any HAI, it increases the length of hospitalization of newborns and neonatal morbidity.
In September 2020, the CDC published recommendations for the prevention and control of Staphylococcus aureus infections in neonatal intensive care unit/ICU. They specify the indications for implementing a MSSA surveillance strategy as well as the screening and management methods.
Despite the absence of a defined strategy at the national level, our establishment chose to initiate management measures several years ago following serious infections and MSSA epidemics in neonatal intensive care unit/ICU.
With the aim of improving the efficiency of care and evaluating the strategy chosen at the establishment, it is necessary to describing
* the epidemiology of MSSA carriage and infections
* cross-transmission of MSSA strains between patients
* the success rate of decolonization
* the sensitivity of detection of digestive carriage by stool swabbing in order to limit the number of samples from newborns. conditions: the Aim of This Study is to Describe Genomic Epidemiology of MSSA in Neonatal ICU studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 120 type: ESTIMATED measure: frequency of MSSA cross transmission as assessed by WGS sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
<|newrecord|> nctId: NCT06267339 id: TD_tRNS briefTitle: Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-04-01 date: 2026-08-31 date: 2024-02-20 date: 2024-02-20 name: Burke Medical Research Institute class: OTHER briefSummary: The goal of this study is to compare motor learning rates on two different tasks, when combined with non-invasive brain stimulation. conditions: Children studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 40 type: ESTIMATED name: transcranial random noise stimulation name: Sham stimulation measure: Change in Grasp score measure: Change in Reach score measure: Change in Graded Redefined Assessment of Strength, Prehension assessment (GRASSP) measure: Change in score on second reaching task sex: ALL minimumAge: 10 Years maximumAge: 17 Years stdAges: CHILD facility: Burke Neurological Institute city: White Plains state: New York zip: 10605 country: United States lat: 41.03399 lon: -73.76291 hasResults: False
<|newrecord|> nctId: NCT06267326 id: Nasser institute briefTitle: World Health Organization (WHO) , COVID19 Case Series of Post Covid 19 Rhino Orbito Cerebral Mucormycosis in Egypt overallStatus: COMPLETED date: 2021-05-23 date: 2022-06-12 date: 2023-08-21 date: 2024-02-20 date: 2024-02-20 name: Nasser Institute For Research and Treatment class: OTHER_GOV briefSummary: Objectives: identify and recognize clinical Characteristics, Pathophysiology, and management of a group of patients with rhino Rhino-Orbito-Cerebral Mucormycosis infection associated with Covid 19 viral infection conditions: Mucormycosis; Rhinocerebral (Etiology) conditions: COVID-19 studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: SINGLE whoMasked: CARE_PROVIDER count: 35 type: ACTUAL name: debridment measure: 35 patients suffering from mucormycosis infection post covid 19 measure: 25 patients were cured with comorbidity and 10 pateints died measure: pain measure: Visual Analog Score for pain sex: ALL minimumAge: 22 Years maximumAge: 77 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Omar Elmonofy city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
<|newrecord|> nctId: NCT06267313 id: 2023-078-PAU briefTitle: Attention Training for COVID-19 Related Distress overallStatus: RECRUITING date: 2024-02-19 date: 2027-02-19 date: 2027-02-19 date: 2024-02-20 date: 2024-04-02 name: Palo Alto University class: OTHER briefSummary: The study aims to test whether attention training (attention bias modification or attention control training) reduces distress or COVID-19 related anxiety compared to a neutral condition. conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT count: 200 type: ESTIMATED name: Attention Bias Modification name: Attention Control Training name: Neutral training measure: COVID-19 Anxiety Syndrome Scale measure: COVID-19 Anxiety Syndrome Scale measure: COVID-19 Anxiety Syndrome Scale measure: COVID-19 Anxiety Syndrome Scale sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Palo Alto University status: RECRUITING city: Palo Alto state: California zip: 94304 country: United States name: Mikael Rubin, PhD role: CONTACT phone: 650-433-3805 email: [email protected] lat: 37.44188 lon: -122.14302 hasResults: False
<|newrecord|> nctId: NCT06267300 briefTitle: Treatment of Post-COVID-19 With Hyperbaric Oxygen Therapy: a Randomized, Controlled Trial overallStatus: NOT_YET_RECRUITING date: 2024-10-01 date: 2025-10-01 date: 2026-04-01 date: 2024-02-20 date: 2024-02-28 name: Erasmus Medical Center class: OTHER name: Da Vinci Clinic name: HGC Rijswijk briefSummary: The goal of this clinical try is to investigate the effect of hyperbaric oxygen therapy (HBOT) on symptoms, quality of life and absence of work through sickness in patients with post-COVID on short- and mid-term, as well as to identify biochemical mechanisms of action.
The main questions it aims to answer are:
* What is the clinical relevance of improvements of symptoms and quality of life after treatment with HBOT for post-COVID?
* What are the changes in absence from work after treatment with HBOT?
* What is the cost-effectiveness of treatment with HBOT?
* What are possible mechanisms of action of HBOT?
Participants will undergo 40 sessions of HBOT. Researchers will compare HBOT with standard care alone (control group). In case of a positive outcome, patients in the control group can cross-over to the HBOT group after 6 months. conditions: Post-COVID-19 Syndrome conditions: Post-COVID Syndrome conditions: Post COVID-19 Condition conditions: Post-COVID Condition conditions: Post COVID-19 Condition, Unspecified conditions: Long COVID conditions: Long Covid19 studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: CROSSOVER interventionModelDescription: Randomized controlled trial comparing HBOT to standard care alone, with a cross-over from standard care to HBOT in case primary outcome is positive after 6 months follow-up. primaryPurpose: TREATMENT masking: NONE count: 120 type: ESTIMATED name: Hyperbaric oxygen measure: Physical and mental component scores of the 36-item Short Form Survey (SF-36) measure: Euroqol-5D (EQ-5D) measure: Activity tracking (through wrist band), monitoring heart rate, step count and sleep patterns measure: Biochemical parameters measure: Absence from work measure: Cost-effectiveness sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Da Vinci Clinic city: Amersfoort country: Netherlands lat: 52.155 lon: 5.3875 facility: Da Vinci Clinic city: Geldrop country: Netherlands lat: 51.42167 lon: 5.55972 facility: Da Vinci Clinic city: Hoogeveen country: Netherlands lat: 52.7225 lon: 6.47639 facility: HGC Rijswijk city: Rijswijk country: Netherlands name: Rutger Lalieu, Dr. role: CONTACT lat: 52.03634 lon: 4.32501 facility: Da Vinci Clinic city: Rotterdam country: Netherlands name: Nina Lansdorp, Dr. role: CONTACT lat: 51.9225 lon: 4.47917 facility: Erasmus MC city: Rotterdam country: Netherlands name: Merel Hellemons, Dr. role: CONTACT lat: 51.9225 lon: 4.47917 facility: Da Vinci Clinic city: Waalwijk country: Netherlands name: Nina Lansdorp, Dr. role: CONTACT lat: 51.6825 lon: 5.07083 hasResults: False
<|newrecord|> nctId: NCT06267287 id: 2023-4 briefTitle: Microbiological Structure of Pathogens of Periprosthetic Infection of Large Joints in the Post-Covid Period overallStatus: COMPLETED date: 2018-01-01 date: 2022-12-31 date: 2022-12-31 date: 2024-02-20 date: 2024-02-20 name: Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty class: OTHER briefSummary: Background. Infection is the most common complication of complications after joint arthroplasty. During the COVID-19 pandemic increased used antibacterial drugs by adults, this could change the spectrum of infectious agents and their antimicrobial resistance. The purpose of the study is to evaluate the microbial diversity of pathogens of periprosthetic infection in the pre- and post-Covid period, determining the sensitivity of the leading pathogens to antibiotics. Materials and methods. A comprehensive comparative retrospective study was carried out on 342 cases of monomicrobial and polymicrobial periprosthetic infection (PPI) of limb joints with microbiological growth of microorganisms in the pre-Covid (2018-2019) and post-Covid (2021-2022) periods. conditions: Joint Infection conditions: Periprosthetic Left Knee Joint Infection studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 342 type: ACTUAL name: Microbiological examination of the patient's biological material and determination of antibiotic resistance measure: Structure of isolated pathogens of periprosthetic infection measure: Structure of isolated pathogens of periprosthetic infection measure: Antibiotic resistance of isolated pathogens of periprosthetic infection measure: Antibiotic resistance of isolated pathogens of periprosthetic infection sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Federal Center for Traumatology, Orthopedics and Endoprosthetics city: Cheboksary state: Chuvashia zip: 429500 country: Russian Federation lat: 56.13222 lon: 47.25194 hasResults: False
<|newrecord|> nctId: NCT06267274 id: MW230021 briefTitle: A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-01 date: 2025-05-01 date: 2024-02-20 date: 2024-03-29 name: Amneal Pharmaceuticals, LLC class: INDUSTRY name: CBCC Global Inc. name: Amneal EU, Limited briefSummary: A randomized, double-blind, parallel-group, two-arm, multiple dose, multicenter, clinical endpoint bioequivalence study conditions: Open-angle Glaucoma conditions: Ocular Hypertension studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Subjects will be randomized in such way that ratio of treatment distribution will be nearer to 1:1 between the treatment arms, and within the combined stratification criteria. primaryPurpose: TREATMENT masking: TRIPLE maskingDescription: double-blind study whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 240 type: ESTIMATED name: Bimatoprost Ophthalmic Solution, 0.01% name: LUMIGAN® (bimatoprost ophthalmic solution) 0.01% measure: Primary Endpoint measure: Secondary Endpoint sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: West Coast Eye Institute city: Bakersfield state: California zip: 93308 country: United States name: Sandeep Walia, MD role: CONTACT lat: 35.37329 lon: -119.01871 facility: Eye Research Foundation city: Newport Beach state: California zip: 92663 country: United States name: David Wirta, MD role: CONTACT lat: 33.61891 lon: -117.92895 facility: Clayton Eye Research city: Morrow state: Georgia zip: 30260 country: United States name: Kim Jong, MD role: CONTACT lat: 33.58317 lon: -84.33937 facility: Houston Eye Associates city: Houston state: Texas zip: 77008 country: United States name: Kevin Jong, MD role: CONTACT lat: 29.76328 lon: -95.36327 hasResults: False
<|newrecord|> nctId: NCT06267261 id: KOL-001 briefTitle: Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure Chamber overallStatus: COMPLETED date: 2021-06-07 date: 2021-08-23 date: 2021-10-25 date: 2024-02-20 date: 2024-02-20 name: Alyatec class: INDUSTRY name: Medicom briefSummary: There is no clinical evidence that face masks are efficient in birch pollen-induced asthma. As the use of face masks has become widespread worldwide to limit the spread of SARS-CoV-2, this study aims to demonstrate the clinical efficacy of medical masks in patients allergic to birch in the same way that clinical trial with drugs. conditions: Allergic Asthma conditions: Allergic Rhinitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: NONE count: 24 type: ACTUAL name: KOLMI® surgical face mask (OP-Air) measure: Time to early asthma response (EAR) measure: Frequency of EAR and late asthma response (LAR) measure: Severity of EAR and LAR measure: Nasal Symptoms sex: ALL minimumAge: 18 Years maximumAge: 55 Years stdAges: ADULT facility: ALYATEC city: Strasbourg country: France lat: 48.58392 lon: 7.74553 hasResults: False
<|newrecord|> nctId: NCT06267248 id: T05100 briefTitle: Spine Registration Using 3D-Scanning acronym: BWH overallStatus: ENROLLING_BY_INVITATION date: 2024-02 date: 2024-11 date: 2024-11 date: 2024-02-20 date: 2024-02-20 name: Advanced Scanners Inc. class: INDUSTRY briefSummary: The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period. conditions: Spine Surgery studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 10 type: ESTIMATED name: Optical 3D Scanner measure: Spine Registration measure: Vertebral Shift Measurement measure: Determination Of Bony Exposure Requirements sex: ALL minimumAge: 18 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Mass General Bringham, Hale Building for Transformative Medicine city: Boston state: Massachusetts zip: 02115 country: United States lat: 42.35843 lon: -71.05977 hasResults: False
<|newrecord|> nctId: NCT06267235 id: lowprotein briefTitle: Dietary Protein Restriction and Health acronym: LOWPRO overallStatus: COMPLETED date: 2018-01-01 date: 2020-01-31 date: 2024-01-31 date: 2024-02-20 date: 2024-04-17 name: University of Copenhagen class: OTHER briefSummary: The incidence of type 2 diabetes worldwide has increased significantly over the past decades, which is associated with changing dietary habits and physical inactivity. According to the diet, so far there has been a great focus on the quality of carbohydrates and fat in relation to metabolic health, while the importance of protein has been neglected. The Danes' average protein intake is 1.5 g/kg/day, which is at the high end of the recommendations (0.8-1.5 g/kg/day) from the Nordic Nutrition Recommendations (NNR 2023). Recent studies in rodents have shown that protein restriction has positive effects on health, including improved glucose and insulin homeostasis and reduced fat mass, while a high intake of protein has a negative effect on insulin sensitivity. Previously the investigators have shown, in healthy young men, that consuming a diet low in protein (0.9 g/kg/day), compared to the participants usual diet (1.5 g/kg/day), over 7 days, resulted in an increased insulin sensitivity as well as a marked increase in the plasma fibroblast growth factor 21 (FGF21) concentration. The increased insulin sensitivity is thought to be mediated by the increase in plasma FGF21 concentration. However, the effect is not yet fully understood. It is also not clear whether the increase in plasma FGF21 concentration, as well as the mentioned metabolic effects on insulin and glucose homeostasis, will take place if the participants are kept weight stable on a eucaloric diet. conditions: Protein conditions: Healthy conditions: Diet studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Longitudinal study changing diet during the intervention 5 weeks restricted dietary protein + 5 weeks habitual dietary protein consumption primaryPurpose: BASIC_SCIENCE masking: NONE count: 23 type: ACTUAL name: Dietary protein restriction measure: Energy balance measure: Insulin sensitivity measure: Adipose tissue proteomics measure: Plasma FGF21 sex: MALE minimumAge: 25 Years maximumAge: 35 Years stdAges: ADULT facility: University of Copenhagen city: Copenhagen zip: 2100 country: Denmark lat: 55.67594 lon: 12.56553 hasResults: False
<|newrecord|> nctId: NCT06267222 id: SCATDCS23 briefTitle: Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia overallStatus: ENROLLING_BY_INVITATION date: 2024-03-04 date: 2024-06-30 date: 2024-07-31 date: 2024-02-20 date: 2024-02-20 name: Laura Alice Santos Oliveira class: OTHER name: Federal Institute of Rio de Janeiro briefSummary: The main goal of this pragmatic clinical trial is to investigate the effects of trans-spinal tDCS in individuals with spinocerebellar ataxia (SCA) over some parameters of gait and postural control in real-world conditions, reflecting daily clinical practice. The main questions it aims to answer are:
* If an extended number of tDCS sessions, beyond the typical 5 to 10 sessions described in scientific literature, applied concomitantly with exercises with progressive challenges, to yield positive outcomes over some parameters of gait and postural control in individuals with SCA and if there is retention of possible benefits one month later the end of this protocol.
* If there is specific characteristics (including balance, gait, mobility, severity of ataxia, DNA test characteristics and non-ataxic signs) in individuals with SCA that can predict their improvement in postural control and gait following the 20 tDCS sessions.
* Participants will receive 20 tDCS sessions concomitantly with exercises for gait and postural control with progressive challenges.
* Postural control and gait of the participants will be assessed in two big sessions before (#assessment 1) and after the 20 sessions (#assessment 5) and 3 small sessions after every 5 sessions (#assessments 2, 3 and 4). Also, as a follow-up, they will be assessed a month after the end of the intervention (#assessment 6). conditions: SCA conditions: Postural Balance conditions: Gait Ataxia studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: This is a pragmatic clinical trial that will be carried out using the CONSORT-Pragmatic Trials (Zwarenstein et al., 2008). primaryPurpose: TREATMENT masking: NONE maskingDescription: THE INVESTIGATOR NOT BE INFORMED ABOUT THE TREATMENT count: 40 type: ESTIMATED name: TRANSCRANIAL DIRECT CURRENT STIMULATION + exercises measure: Postural control measure: Mobility measure: Gait performance measure: The subjective experience of the participants regarding the protocol. sex: ALL minimumAge: 18 Years maximumAge: 70 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Anna Fontes Baptista city: Rio de Janeiro state: RJ zip: 21032-060 country: Brazil lat: -22.90278 lon: -43.2075 hasResults: False
<|newrecord|> nctId: NCT06267209 id: He-Modulation briefTitle: Conditioned Pain Modulation in Patients With Hemophilia overallStatus: NOT_YET_RECRUITING date: 2024-02-19 date: 2024-03-03 date: 2024-04-20 date: 2024-02-20 date: 2024-02-20 name: Investigación en Hemofilia y Fisioterapia class: NETWORK briefSummary: Introduction: Hemophilic arthropathy is characterized by functional alterations, disabling physical sequelae, and chronic pain. Conditioned pain modulation describes the net effect of endogenous pathways that enhance or diminish the effects of afferent noxious stimuli.
Objectives: To describe conditioned pain modulation in patients with hemophilia and identify the best predictive model of conditioned pain modulation in these patients Methods: Cross-sectional cohort study. 51 patients with hemophilic arthropathy will be recruited in 3 regions of Spain. The main study variable will be the conditional pain modulation (Conditioned Pain Modulation Index, using an ischemic technique of the arm using the pain pressure threshold as a test stimulus), with age being the dependent variable. The secondary variables, estimated as modifying or confounding variables, will be kinesiophobia (Tampa Scale for Kinesiophobia), catastrophizing (Pain Catstrophizing Scale), trait and state anxiety (State-Trait Anxiety Inventory) and the main clinical, anthropometric, and sociodemographic.
Expected results: Identify the degree of modulation conditioned by pain in patients with hemophilic arthropathy. Identify the best predictive model for conditioned pain modulation in these patients based on the study variables conditions: Hemophilia studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 51 type: ESTIMATED name: Observational group measure: Assess the Conditioned Pain Modulation Index measure: Assess the kinesiophobia with Tampa Scale of Kinesiophofia measure: Assess the catastrophizing with Pain catastrophizing scale measure: Assess the catastrophizing with State-Trait Anxiety Inventory measure: Assess the joint damage with Haemophilia Joint Health Score measure: Assess the joint pain with visual analog scale measure: Assess the pressure pain threshold with pressure algometer measure: Assess the functional capacity with the 6-Minute Walking test sex: MALE minimumAge: 20 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: University of Oviedo city: Oviedo state: Asturias zip: 33006 country: Spain name: Rubén Cuesta-Barriuso, PhD role: CONTACT lat: 43.36029 lon: -5.84476 hasResults: False
<|newrecord|> nctId: NCT06267196 id: CemilTascıogluERHO-AYAN briefTitle: The Effect of the Stress Ball Used During Spinal Anesthesia on Pain and Anxiety acronym: stressball overallStatus: RECRUITING date: 2023-11-02 date: 2024-03-02 date: 2024-03-15 date: 2024-02-20 date: 2024-02-20 name: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization class: OTHER briefSummary: The aim is to determine the impact of the stress ball used during spinal anesthesia on pain and anxiety levels conditions: Pain conditions: Anxiety studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 140 type: ESTIMATED name: The use of a stress ball measure: stress ball and anxiety measure: stress ball and pain measure: Stress ball and blood pressure measure: Stress ball and pulse measure: Stress ball and saturation sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Özge Sayın Ayan status: NOT_YET_RECRUITING city: Istanbul state: Eyup zip: 34065 country: Turkey name: özge sayın role: CONTACT phone: +905332965628 email: [email protected] name: volkan özen role: CONTACT phone: +905309276094 email: [email protected] lat: 41.01384 lon: 28.94966 facility: Prof.Dr.Cemil Tascioglu City Hospital status: RECRUITING city: Istanbul state: Şişli zip: 34360 country: Turkey name: özge sayın ayan role: CONTACT phone: +905332965628 email: [email protected] name: volkan özen role: CONTACT phone: +905309276094 email: [email protected] lat: 41.01384 lon: 28.94966 hasResults: False
<|newrecord|> nctId: NCT06267183 id: SV001-101 briefTitle: A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers. overallStatus: RECRUITING date: 2024-01-12 date: 2024-11-30 date: 2025-03-30 date: 2024-02-20 date: 2024-02-20 name: Shanghai Synvida Biotechnology Co.,Ltd. class: INDUSTRY briefSummary: The purpose of this study is to evaluate safety, tolerability, PK and immunogenicity of SV001 compare to placebo in Chinese healthy adult volunteers. conditions: Idiopathic Pulmonary Fibrosis studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 53 type: ESTIMATED name: SV001 name: Placebo measure: Incidence of Treatment-Emergent Adverse Events measure: Peak Plasma Concentration (Cmax) measure: Peak time(Tmax) measure: Area under the plasma concentration versus time curve (AUC) measure: half-life(T1/2) measure: Immunogenicity sex: ALL minimumAge: 18 Years maximumAge: 45 Years stdAges: ADULT facility: Shanghai Xuhui District Central Hospital status: RECRUITING city: Shanghai country: China name: Qian Chen role: CONTACT phone: 0086-021-54036058 email: [email protected] lat: 31.22222 lon: 121.45806 hasResults: False
<|newrecord|> nctId: NCT06267170 id: SCLC-RWS-001 briefTitle: A Multicenter, Real-world Study of Adebrelimab in the Treatment of Extensive Stage Small Cell Lung Cancer acronym: SCLC overallStatus: NOT_YET_RECRUITING date: 2024-02-25 date: 2025-02-25 date: 2026-02-25 date: 2024-02-20 date: 2024-02-20 name: Henan Cancer Hospital class: OTHER_GOV briefSummary: This study collected data on patients with extensive stage small cell lung cancer treated with Adebrelimab to investigate its safety and efficacy conditions: SCLC,Extensive Stage studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 288 type: ESTIMATED name: Adebrelimab measure: Safety (Occurrence of ≥ Grade 3 AE) measure: PFS measure: ORR measure: OS measure: DCR sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
<|newrecord|> nctId: NCT06267157 id: 2023/23 briefTitle: Breastfeeding Consultant Training in the Metvaverse Universe overallStatus: NOT_YET_RECRUITING date: 2024-03-20 date: 2024-05-20 date: 2024-07-02 date: 2024-02-20 date: 2024-02-20 name: Gulhane School of Medicine class: OTHER briefSummary: Although breastfeeding is an important and natural process in infant development, mothers may fail to manage the process. Nurses, who have an important place in helping to physically initiate and maintain breastfeeding, provide an in-depth knowledge of breast anatomy and breastfeeding physiology, practice and process breastfeeding techniques. Must have extensive management skills. Although the World Health Organization recommends that breastfeeding issues should be addressed in medical, nursing and midwifery schools, there is a lack of nurses' training curricula and breastfeeding training given in hospitals. Due to this deficiency, mothers have low self-confidence and insufficient knowledge about breastfeeding.
The aim of this project is to develop a breastfeeding counseling model in the metaverse universe and to determine the effect of this model on nursing students' breastfeeding counseling skills, knowledge level and empathy skills. Giving breastfeeding education with the metaverse application compared to the application on real patients includes much less risk for the patient and the ability to practice until the right skill is acquired. In the project, it is expected that the breastfeeding counseling education model (LactaVerse), which is structured on virtual reality developed in the metaverse universe, is compared to the existing deficient and non-standardized breastfeeding education practice, enabling nurses to practice more and without errors during the undergraduate education, and to gain more effective skills in breastfeeding counseling. In this context, the project will support the ability of multiple users in the metaverse universe to examine the anatomy of the breast and apply breastfeeding counseling to the mother by transmitting their voices and movements with virtual glasses.
In the preparation phase of the training to be developed in the virtual universe within the scope of the project, the breast anatomical modeling and the breastfeeding mother-baby duo project scenario will be developed and virtual glasses will be transferred. At this stage, expert opinions of the questionnaires to be used in the evaluation of educational effectiveness will be taken. Pre-application of data collection tools and LactaVerse training will be made. Experiment (n=40) and control (n=40) groups will be determined from the students by randomization. "Descriptive Characteristics Data Collection Form", "Breastfeeding Information Form", "Basic Empathy Level Scale", "Nursing Counseling Skill Scale" and "Presence Scale" will be applied to both groups. During the application phase, Lactaverse training method with virtual glasses will be applied to the experimental group, and a 2-hour theoretical classical training method will be applied to the control group. After 4 weeks of the training, the post-tests will be applied to the experimental group and the control group and they counseling will be given to the patient who plays the role of a nursing mother in the laboratory, and measurements will be made with the Breastfeeding Counseling Skill List and statistical analyzes will be applied.
With the training developed in connection with the project, it is expected that nurses will have a high level of empathy development and breastfeeding counseling skills in a complex healthcare environment such as breastfeeding counseling before they graduate. In this way, the professional knowledge, counseling skills and empathy skills of nurses, who have an important role in breastfeeding, will increase, helping our society to increase the breastfeeding rates to the desired level. conditions: Breast Feeding studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: OTHER masking: DOUBLE whoMasked: PARTICIPANT whoMasked: OUTCOMES_ASSESSOR count: 22 type: ESTIMATED name: virtual reality training name: theoretical breastfeeding training measure: Introductory Features Data Collection Form measure: Breastfeeding Information Form measure: Basic Empathy Level Scale measure: Breastfeeding Teaching Skill Evaluation Form measure: Presence Scale sex: ALL stdAges: CHILD stdAges: ADULT stdAges: OLDER_ADULT facility: Gulhane Faculty of Nursing city: Ankara country: Turkey name: Gulten Guvenc role: CONTACT email: [email protected] lat: 39.91987 lon: 32.85427 hasResults: False
<|newrecord|> nctId: NCT06267144 id: 23K237-001 briefTitle: Detection of Minimal Residual Disease in Resectable Stage II-IIIB Non-small Cell Lung Cancer overallStatus: RECRUITING date: 2024-01-20 date: 2025-06-01 date: 2025-12-17 date: 2024-02-20 date: 2024-02-20 name: The First Hospital of Jilin University class: OTHER briefSummary: Predicting relapse and overall survival in potentially resectable Stage IIIA-IIIB Non-small Cell Lung Cancer (NSCLC) patients remains challenging. It is now widely recognized that patients with detectable MRD have a worse prognosis than those with undetectable MRD. Therefore, investigators performed this prospective clinical trial to evaluate the predictive value of MRD with increased risk of relapse and improves prediction of outcome in potentially resectable Stage IIIA-IIIB NSCLC with neoadjuvant chemoimmunotherapy. In this study, investigators will pay more attention to the long-term follow-up time and dynamic monitoring of MRD. The predictive value of MRD with Disease-free survival (DFS) rate was observed as the primary endpoint. Besides that, the correlation of MRD with major pathologic response (MPR) rate, pathologic complete response (pCR) rate,event-free survival(EFS) rate and overall survival (OS) were observed as the second endpoints. Investigators hope it will provide a new insight for these potentially resectable Stage IIA-IIIB NSCLC with neoadjuvant chemoimmunotherapy. conditions: Lung Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 20 type: ESTIMATED name: Sintilimab plus chemotherapy measure: Event free survival(EFS) measure: Overall Survival (OS) measure: Objective Response Rate (ORR) measure: Disease-Control Rate (DCR) measure: Pathological complete response rate(PCR) measure: Major pathological response rate (MPR) sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: The First Hospital Of Jilin University status: RECRUITING city: Changchun state: Jilin zip: 130000 country: China name: Ma Kewei role: CONTACT phone: 0431-88782222 lat: 43.88 lon: 125.32278 hasResults: False
<|newrecord|> nctId: NCT06267131 id: IRB 22-1286 briefTitle: Transcutaneous Pulse Oximetry Brain Monitoring Study (US) acronym: T-POT US overallStatus: RECRUITING date: 2023-10-27 date: 2024-11 date: 2024-11 date: 2024-02-20 date: 2024-02-20 name: Cyban Pty Ltd class: INDUSTRY briefSummary: This is a study of adult patients with a severe and sudden brain injury who have a drain placed in their brain to measure pressure. The purpose of the study is to monitor the pressure in the brain using a monitor placed on the forehead, and compare this to a drain placed in the brain. conditions: Acute Brain Injury studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Single center prospective observational cohort study primaryPurpose: DIAGNOSTIC masking: NONE count: 15 type: ESTIMATED name: Brain Pulse Oximeter measure: Agreement of the brain oximeter levels compared with invasive ICP levels measure: Optical signal changes associated with periods of brain hypoxia and surrogate ICP waveform measure: Optical signal changes associated with non-convulsive seizures via EEG monitoring (Alpha, Beta, Theta) sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Cleveland Clinic, Neurological Institute status: RECRUITING city: Cleveland state: Ohio zip: 44195 country: United States name: Catherine Hassett, DO role: CONTACT phone: 216-445-1385 email: [email protected] name: Joao Gomes, MD role: CONTACT phone: 216-445-1385 email: [email protected] lat: 41.4995 lon: -81.69541 hasResults: False
<|newrecord|> nctId: NCT06267118 id: Treatment of Bronchiolitis briefTitle: Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis acronym: children overallStatus: RECRUITING date: 2023-11-01 date: 2024-04-30 date: 2024-05-31 date: 2024-02-20 date: 2024-02-20 name: Combined Military Hospital, Pakistan class: OTHER briefSummary: The goal of this clinical trial is to compare the efficacy of hypertonic saline nebulization with adrenaline nebulization in the treatment of acute bronchiolitis in children. Main aim is to evaluate the following in both group of patients
1. Improvement in Wood-Downes clinical score (WDF score) in bronchiolitis
2. Length of Hospitalization conditions: Acute Bronchiolitis Due to Respiratory Syncytial Virus studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Patients with acute bronchiolitis after informed written consent will be divided into two groups randomly. Group I will be nebulized with adrenaline every 6 hours and group II will nebulized with hypertonic saline every 6 hours. After 24 hours and 48 hours of nebulization, WDF score will be recorded by measuring respiratory rate, heart rate, chest retractions, chest auscultation findings and SPO₂ levels. Researcher will record all data on a specified Performa. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Investigator will make all the protocol and research Performa. Drugs will already be prepared for nebulization and labelled by investigator. Researcher /care provider will nebulize the patients of both groups randomly and record the results accordingly. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER count: 60 type: ESTIMATED name: Hypertonic Saline Solution, 1 Ml name: Adrenaline measure: Wood-Downes-Ferres clinical score calculation measure: total length of hospitalization sex: ALL minimumAge: 1 Month maximumAge: 2 Years stdAges: CHILD facility: Combined Military Hospital status: RECRUITING city: Nowshera state: KPK zip: 24110 country: Pakistan name: Syed Qamar Zaman role: CONTACT phone: 00923365307823 email: [email protected] name: Shahid Mahmud role: CONTACT phone: 00923315301289 email: [email protected] name: Syed Qamar Zaman role: PRINCIPAL_INVESTIGATOR hasResults: False
<|newrecord|> nctId: NCT06267105 id: A1-LORT briefTitle: A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin. overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-02 date: 2025-03 date: 2024-02-20 date: 2024-02-20 name: Corporacion Parc Tauli class: OTHER briefSummary: Trigger finger is a common pathology in the hand. Patients suffer from pain and depending on which tasks, patients have difficulty to perform them. Its treatment in initial and less serious phases includes conservative measures, but failure of these may require releasing the trigger finger with surgery. The surgical technique performed for trigger finger is the opening of the A1 pulley, the skin incisions used for this surgery are various (transverse, longitudinal, oblique). Trigger finger surgery presents good results in terms of resolution, but complications may also occur. The reason for this study is to assess whether there are functional differences using the Dash scale when we perform a transverse or longitudinal incision in trigger finger surgery. conditions: Functional Disturbance as Result studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 36 type: ESTIMATED name: Longitudinal incision name: Transverse incision measure: Functional improvement of the patient after surgery measure: Surgeon comfort measure: Resolution measure: Flushed measure: Pain feeling measure: Contracture measure: Infection measure: Nerve injury measure: Return to work measure: Reincorporation to activities measure: Sensitivity Test sex: ALL minimumAge: 18 Years maximumAge: 100 Years stdAges: ADULT stdAges: OLDER_ADULT hasResults: False
<|newrecord|> nctId: NCT06267092 id: NN9838-4944 briefTitle: A Study of How CagriSema Works on Appetite in People With Excess Body Weight overallStatus: RECRUITING date: 2024-02-15 date: 2026-01-19 date: 2026-01-19 date: 2024-02-20 date: 2024-02-28 name: Novo Nordisk A/S class: INDUSTRY briefSummary: Part A: The study will look at participants appetite and energy intake and also look at the mechanisms of brain associated with appetite and food intake. Participants will not get any medicine and will be in a group that will be compared to another group receiving a weight-loss medicine. The study will last for about 6 months.
Part B: The study will look at how CagriSema works on participants appetite and energy intake and will be compared with a ''dummy'' medicine. The study will also look at how participants brain works when participants take the medicine. Participants will either get CagriSema or ''dummy'' medicine. conditions: Overweight conditions: Obesity studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: QUADRUPLE maskingDescription: Sponsor staff involved in the clinical trial is masked according to company standard procedures. whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 150 type: ESTIMATED name: No treatment given name: Cagrilintide and Semaglutide name: Placebo measure: Change in mean postprandial appetite score based on visual analogue scale (VAS) measure: Change in mean postprandial VAS ratings of: hunger, fullness, satiety and prospective food consumption measure: Change in average DAILY EATS questionnaire scores over one week for: average hunger, worst hunger, appetite, cravings, satiety and eating drivers index composite score measure: Change in control of eating questionnaire (COEQ), 4 domains: craving control score, positive mood score, craving for sweets score and craving for savoury food score measure: Change in power of food questionnaire for: food available score, food present score, food tasted score and composite score measure: Change in blood oxygen level dependant (BOLD) response to food cues in the brain reward areas measure: Relative change in total energy intake during ad libitum lunch, evening meal and snackbox measure: Change in percent energy intake of high fat, sweet food in total ad libitum energy intake in the evening snack box measure: Change in total energy intake during ad libitum lunch, evening meal and snackbox measure: Change in total amount of food consumed during ad libitum lunch, evening meal and snackbox measure: Change in body weight sex: ALL minimumAge: 18 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Charité Research Organisation GmbH status: RECRUITING city: Berlin zip: 10117 country: Germany lat: 52.52437 lon: 13.41053 hasResults: False
<|newrecord|> nctId: NCT06267079 id: core stability briefTitle: Core Stability, Symmetrical Weight-bearing Stroke overallStatus: COMPLETED date: 2023-06-01 date: 2023-09-05 date: 2024-01-01 date: 2024-02-20 date: 2024-02-20 name: Cairo University class: OTHER briefSummary: To evaluate the effect of core stability exercise on symmetrical weight bearing in chronic stroke patients? conditions: Stroke studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 40 type: ACTUAL name: core stability exercise measure: Each patient was assessed by Balance Berg scales pretreatment. and repeated Measurements were taken after treatment. Each patient was assessed by Digital weight scale and Balance Berg scales measure: Each patient was assessed by Digital weight scale pre treatment and repeated Measurements were taken after treatment. sex: ALL minimumAge: 50 Years maximumAge: 65 Years stdAges: ADULT stdAges: OLDER_ADULT facility: faculty of physical therapy Cairo university city: Cairo country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
<|newrecord|> nctId: NCT06267066 id: MD-232-2022 briefTitle: Fractional Carbon Dioxide Laser: A Novel Therapeutic Option for Lichen Simplex Chronicus overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-08-01 date: 2024-08-30 date: 2024-02-20 date: 2024-02-20 name: Cairo University class: OTHER briefSummary: The goal of this randomized control trial is to compare the use of fractional carbon dioxide (Co2) laser to topical corticosteroids to treat lichen simplex chronicus (LSC) patients presenting to Dermatology outpatient clinic, Faculty of Medicine, Cairo University.
Participants will:
* Be assessed clinically by doctor
* Biopsies will be taken from them by doctor
* Receive treatment as laser or topical steroids or both
* Fill in depression questionnaire.
Researchers will divide and compare groups as follows:
Sixty patients will be divided randomly through closed envelop technique into 2 groups (Group A and B) each of 30 patients. Group A will be subdivided into 2 groups (1 and 2). All LSC lesions will be treated in any patient having multiple lesions.
* Group 1 - A: Patients will receive 3 monthly laser sessions, in addition to the use of topical emollients only once daily in between the sessions.
* Group 2 - A: Patients will receive 3 monthly laser sessions, in addition to topical steroids twice daily and topical emollient once daily in between the sessions.
* Group B: Patients will be prescribed topical steroids twice daily and topical emollient once daily for 3 months.
to see if:
1. Pruritus severity scale.
2. Scaling, erythema, lichenification excoriation scores
3. Visual analogue scale.
4. Investigator's Global Assessment.
5. Itching mediators (Interleukin-31, Nerve Growth Factor and Substance P assays (itching mediators)
6. Depression
improve more in which group of patients after treatment. conditions: Lichen Simplex Chronicus studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Sixty patients will be divided randomly through closed envelop technique into 2 groups (Group A and B) each of 30 patients. Group A will be subdivided into 2 groups (1 and 2) each of 15 patients. All LSC lesions will be treated in any patient having multiple lesions.
Group 1 - A: Patients will receive 3 monthly laser sessions, in addition to the use of topical emollients only once daily in between the sessions.
Group 2 - A: Patients will receive 3 monthly laser sessions, in addition to topical steroids twice daily and topical emollient once daily in between the sessions.
Group B: Patients will be prescribed topical steroids twice daily and topical emollient once daily for 3 months. primaryPurpose: TREATMENT masking: SINGLE maskingDescription: Experienced dermatologist blinded to the interventions done will assess the patients' at the end of the treatment period. whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: Betamethasone Valerate 0.1% Cream name: SmartXide® fractional carbon dioxide laser name: Vaseline Topical Product measure: Comparison between 2 groups regarding change in Pruritus severity scale measure: Comparison between 2 groups regarding change in Visual analogue scale measure: Comparison between 2 groups regarding change in Investigator's Global Assessment. measure: Comparison between 2 groups regarding change in Scaling score measure: Comparison between 2 groups regarding change in Erythema score measure: Comparison between 2 groups regarding change in Lichenification score measure: Comparison between 2 groups regarding change in Excoriation score measure: change of depression score in both groups. measure: change of itching mediators' levels (IL-31, Nerve Growth Factor and substance) between 2 groups measure: Comparison of itching mediator's levels in lesional, non-lesional skin and healthy controls sex: ALL minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Lobna Alieldin city: Cairo zip: 11562 country: Egypt name: Noha Asem, professor role: CONTACT phone: 01003657120 phoneExt: 20 email: [email protected] name: Lobna Alieldin, MSc role: CONTACT phone: 01002279968 phoneExt: 20 email: [email protected] name: Lobna Alieldin role: PRINCIPAL_INVESTIGATOR lat: 30.06263 lon: 31.24967 facility: Lobna Alieldin city: Cairo zip: 11562 country: Egypt lat: 30.06263 lon: 31.24967 hasResults: False
<|newrecord|> nctId: NCT06267053 id: 2023/469 briefTitle: Relationship Between Vitamins and Radiologic Stage in Knee Osteoarthritis overallStatus: COMPLETED date: 2023-12-01 date: 2024-01-20 date: 2024-01-20 date: 2024-02-20 date: 2024-02-20 name: Bakirkoy Dr. Sadi Konuk Research and Training Hospital class: OTHER_GOV briefSummary: The aim of this study is to investigate the relationship between folic acid, vitamin B12 and 25-OH vitamin D levels and radiographic staging in patients diagnosed with primary gonarthrosis. conditions: Knee Osteoarthritis studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: CROSS_SECTIONAL count: 104 type: ACTUAL name: Direct digital radiography name: 25-OH Vitamin D name: Vitamin B12 name: Folic acid measure: 25-OH Vitamin D (25(OH)D) and Kellgren Lawrence Grade measure: Vitamin B12 and Kellgren Lawrence Grade measure: Folic acid and Kellgren Lawrence Grade sex: ALL minimumAge: 50 Years maximumAge: 80 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Bakirkoy Dr. Sadi Konuk Research and Training Hospital city: Istanbul country: Turkey lat: 41.01384 lon: 28.94966 hasResults: False
<|newrecord|> nctId: NCT06267040 id: 17 Al-KindyCM briefTitle: Linguistic and Clinical Validation of the Arabic Version of Acute Cystitis Symptom Score (ACCS) overallStatus: RECRUITING date: 2023-09-01 date: 2024-04-15 date: 2024-04-30 date: 2024-02-20 date: 2024-04-16 name: Al-Kindy College of Medicine class: OTHER briefSummary: The goal of this prospective observational study is to provide an Arabic translation of the Acute Cystitis Symptom Score (ACSS) and to test the linguistic validity and clinical reliability of the translated Arabic version of ACCS (Arabic-ACCS) in Arabic-speaking women older than 18 years of age diagnosed with uncomplicated cystitis.
The main questions it aims to answer are:
* Do the questions of the Arabic-ACSS have sufficient clarity?
* Can the Arabic-ACCS serve its purpose in identifying the presence of uncomplicated cystitis in Arabic-speaking women? The participant will be asked to fill out the Arabic-ACCS questionnaire at the time of diagnosis. The participants will be asked to fill out the second part of the Arabic-ACCS questionnaire 5-10 days later after receiving the appropriate treatment according to the local health policy as prescribed by the treating physician.
Researchers will compare the results from the patients who filled out the first part of the questionnaire with the results of a comparable group of women who were presented with complaints unrelated to the lower urinary tract. conditions: Cystitis Acute studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 200 type: ESTIMATED measure: Linguistic validity measure: Clinical reliability sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Al-Elwiya Maternity Teaching Hospital status: RECRUITING city: Baghdad zip: 10064 country: Iraq name: Zahraa Muhmmed Jameel Al-Sattam, FICMS (Gyn.) role: PRINCIPAL_INVESTIGATOR name: Weqar Akram Hussein, FICMS (Gyn.) role: SUB_INVESTIGATOR lat: 33.34058 lon: 44.40088 facility: Alkindy Teaching Hospital status: RECRUITING city: Baghdad zip: 10064 country: Iraq name: Harth Mohamed Kamber, FICMS (Uro.) role: CONTACT phone: +9647706029071 email: [email protected] name: Harth Mohamed Kamber, FICMS (Uro.) role: PRINCIPAL_INVESTIGATOR name: Ahmed Abed Marzook, FICMS role: SUB_INVESTIGATOR lat: 33.34058 lon: 44.40088 hasResults: False
<|newrecord|> nctId: NCT06267027 id: 2022/125 briefTitle: Comparison of Different Physical Therapy Modalities in Lateral Epicondylitis overallStatus: COMPLETED date: 2023-02-07 date: 2023-09-15 date: 2023-12-15 date: 2024-02-20 date: 2024-02-20 name: Bakirkoy Dr. Sadi Konuk Research and Training Hospital class: OTHER_GOV briefSummary: Comparison of the effects of kinesiotaping and high intensity laser therapy in patients with lateral epicondylitis: a randomized controlled study conditions: Lateral Epicondylitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: RANDOMIZED CONTROLLED STUDY primaryPurpose: TREATMENT masking: SINGLE whoMasked: INVESTIGATOR count: 55 type: ACTUAL name: Exercise name: Kinesiotaping name: High intensity laser therapy measure: Patient Rated Tennis Elbow Evaluation (PRTEE) measure: Visual Analogue Scale (VAS) measure: Quick Disabilities of the Arm, Shoulder and Hand (qDASH) measure: Jamar's handheld dynamometer sex: ALL minimumAge: 18 Years maximumAge: 75 Years stdAges: ADULT stdAges: OLDER_ADULT facility: BakirkoySadiKonuk city: Bakırköy state: İstanbul zip: 34147 country: Turkey hasResults: False
<|newrecord|> nctId: NCT06267014 id: 2023-A02163-42 briefTitle: Use of a Virtual Reality Cognitive Stimulation Programme for Breast Cancer Patients Wishing to Restart or Maintain a Professional Activity acronym: Cog-RV overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-06 date: 2025-06 date: 2024-02-20 date: 2024-02-20 name: Centre Francois Baclesse class: OTHER briefSummary: The study concerns patients who have been treated for breast cancer, have cognitive problems and are planning to return to work or are currently working and wish to begin cognitive rehabilitation.
Patients will follow the Virtual Reality program developed for the study, during the cognitive rehabilitation usually proposed in the establishment, at the rate of a weekly session of 10-15 minute for 6 weeks. conditions: Breast Cancer conditions: Cancer-related Cognitive Difficulties studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Patients will follow the Virtual Reality program developed for the study, during the cognitive rehabilitation sessions primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 23 type: ESTIMATED name: Virtual Reality sessions measure: Proportion of patients adhering to the Virtual Reality program sex: FEMALE minimumAge: 18 Years stdAges: ADULT stdAges: OLDER_ADULT facility: Centre François Baclesse city: Caen country: France name: Adeline MOREL, MD role: CONTACT lat: 49.18585 lon: -0.35912 hasResults: False