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0060132598-19.layout.json
[ "ADVERTISING", "TOOL", "MEDIA", "VEHICLES", "O", "MAGAZINES", "O", "OUTDOOR", "O", "NEWSPAPERS" ]
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513839252_513839291-39.layout.json
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0060132598-5.layout.json
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11300117-0136-7.layout.json
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505859719_505859723-4.layout.json
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2057719268.layout.json
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0060143407-4.layout.json
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2051554123_2051554127-3.layout.json
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501302256_501302323-65.layout.json
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2046807567_7643-62.layout.json
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2085177225.layout.json
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2070864344.layout.json
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531376115+-6129-7.layout.json
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501565196.layout.json
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2046807567_7643-52.layout.json
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0001039501-24.layout.json
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2073874045_4052-4.layout.json
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524860047+-0116-55.layout.json
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500692166_500692218-30.layout.json
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501302256_501302323-36.layout.json
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524860047+-0116-69.layout.json
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50517337-7342-1.layout.json
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"of", "Cheney", "and", "Sprent", "(14).", "After", "several", "attempts,", "we", "were", "unable", "to", "induce", "syngeneic-GVHD", "in", "young", "adult", "(8-12", "weeks)", "DBA/2", "mice", "(data", "not", "shown).", "Subse-", "quently,", "a", "slight", "modification", "of", "the", "procedure", "established", "in", "the", "rat", "model", "to", "induce", "syngeneic", "GVHD", "by", "Beschorner", "et", "al.", "(20)", "was", "adopted.", "This", "procedure", "differed", "from", "that", "of", "Cheney", "and", "Sprent", "in", "that", "the", "dosage", "of", "CsA", "was", "higher", "{15", "vs.", "10", "mg/", "kg/day),", "and", "immunosuppression", "with", "CsA", "was", "initiated", "at", "the", "time", "of", "bone", "marrow", "transplantation", "as", "opposed", "to", "3", "days", "after", "bone", "marrow", "transplantation.", "In", "addition", "to", "the", "above", "changes,", "3-4", "weeks", "instead", "of", "8-12-week-old", "animals", "were", "used", "because", "it", "had", "been", "found", "that", "syngeneic", "GVHD", "was", "induced", "more", "readily", "in", "young", "compared", "to", "old", "rats", "(12,", "13,", "21).", "Lethally", "irradiated", "DBA/2", "mice", "were", "reconstituted", "with", "syngeneic", "mar-", "row", "and", "then", "treated", "for", "21", "days", "with", "either", "CsA", "or", "diluent.", "Within", "1", "week", "after", "cessation", "of", "CsA", "treatment,", "animals", "began", "to", "exhibit", "clinical", "signs", "characteristic", "of", "acute", "GVHD:", "runting", "loss),", "hunched", "posture,", "and", "development", "of", "severe", "diarrhea", "(22).", "The", "syngeneic-GVHD-like", "disease", "(syngeneic", "GVHD)", "that", "developed", "after", "discontinuing", "CsA", "treatment", "was", "fatal", "for", "all", "the", "animals", "that", "survived", "the", "CsA", "treatment", "period", "(Fig.", "1A).", "The", "percentage", "of", "survival", "shown", "in", "Figure", "1", "has", "been", "adjusted", "to", "100%", "and", "represents", "animals", "that", "were", "alive", "at", "day", "21", "after", "bone", "marrow", "transplantation.", "Typically,", "50%", "of", "CsA-treated", "bone-marrow-reconstituted", "animals", "died", "within", "the", "1st", "7-10", "days", "posttransplantation.", "In", "contrast,", "no", "mortality", "or", "clinical", "abnormalities", "were", "observed", "in", "normal", "DBA/2", "mice", "treated", "comparably", "with", "CsA", "(data", "not", "shown).", "A", "majority", "of", "the", "reconstituted", "animals", "that", "survived", "the", "complete", "course", "of", "CsA", "died", "within", "the", "1st", "4", "weeks", "after", "cessation", "of", "treatment.", "In", "all", "experiments,", "animals", "that", "appeared", "moribund", "were", "sac-", "rificed", "and", "were", "recorded", "as", "mortalities.", "Death", "of", "the", "treated", "mice", "was", "preceded", "by", "weight", "loss", "and", "severe", "diarrhea.", "The", "weight", "profiles", "of", "diluent", "control", "and", "CsA-treated", "mice", "are", "depicted", "in", "Figure", "1B.", "During", "the", "CsA-treatment", "period", "(days", "0-21),", "both", "control", "and", "CsA-treatment", "groups", "increased", "in", "average", "body", "weight.", "However,", "over", "the", "remainder", "of", "the", "ex-", "periment,", "CsA-treated", "animals", "lost", "weight,", "falling", "to", "25-30%", "of", "day", "21", "posttransplant", "body", "weight.", "Diluent", "control", "animals", "gained", "weight", "over", "the", "entire", "period", "of", "the", "experiment", "and", "displayed", "no", "sign", "of", "overt", "disease,", "with", "all", "of", "the", "animals", "surviving.", "While", "we", "were", "able", "to", "induce", "syngeneic", "GVHD", "in", "DBA/2", "mice", "(H-2%),", "we", "were", "unable", "to", "do", "so", "when", "an", "identical", "indue-", "tion", "protocol", "was", "performed", "on", "BALB/c", "mice", "(H-29).", "As", "seen", "in", "Figure", "2A,", "BALB/c", "animals", "did", "not", "readily", "develop", "a", "fatal", "disease", "as", "the", "CsA-treated", "mice", "had", "a", "survival", "rate", "similar", "to", "the", "diluent-treated", "mice.", "In", "addition,", "following", "cessation", "of", "CsA,", "the", "treated", "animals", "gained", "weight", "at", "a", "rate", "equal", "to", "that", "of", "control", "animals", "(Fig.", "2B).", "Taken", "together,", "this", "data", "would", "BRYSON", "ET", "AL.", "1043", "A", "|", "100w", "I’_.Y", "t\"-'“)l", "80", ".‘o\\", "B—", "B", "Controt", "[", "T", "1", "2", "60", "*", "§", "4w", "“R", "5", "*..", "a", "e", ".", "20", "i", "%,", "(=30)", ":", "\"", "oLb—f—4", "s", "0", "20", "30", "40", "50", "&0", "70", "80", "Time", "(days)", "after", "Transpiont", "B", "20", "!", ".J../I.H'le.", "\"", "ul", "3", "ol", ":;:", "15}", ":", "R", "@", "0", "¥", ".‘.’:’", "_9®%-g0", "§", "10", "s", "Sheemegsin", "'\\.", "z", "w9}", "§", "3", "Ly", "3", "121", "o", "0", "10", "20", "30", "40", "50", "80", "70", "80", "Time", "(days)", "ofter", "Transplant", "FiGUrE", "1.", "(A)", "Survival", "curves", "of", "DBA/2", "mice", "following", "the", "induc-", "tion", "of", "syngeneic", "GVHD.", "Mice", "were", "irradiated,", "reconstituted", "with", "syngeneic", "marrow,", "and", "treated", "with", "CsA,", "15", "mg/kg/day", "for", "21", "days", "as", "described", "in", "the", "Materials", "end", "Methods", "section.", "Percentage", "of", "survival", "was", "adjusted", "to", "100", "percent,", "which", "represents", "animals", "that", "were", "alive", "at", "day", "21", "after", "bone", "marrow", "transplantation.", "The", "data", "presented", "are", "the", "pooled", "results", "from", "3", "experiments.", "The", "numbers", "in", "parentheses", "represent", "the", "number", "of", "animals", "in", "each", "treatment", "group.", "All", "the", "irradiation", "control", "animals", "(n=30)", "were", "dead", "by", "day", "15", "posttransplan-", "tation.", "(B)", "Weight", "profiles", "of", "DBA/2", "mice", "following", "induction", "of", "syngeneic", "GVHD,", "Animals", "within", "each", "group", "were", "weighed", "three", "times", "weekly", "post-CsA", "treatment,", "and", "the", "average", "weight", "for", "each", "group", "determined.", "The", "numbers", "in", "parentheses", "represent", "the", "number", "of", "animals", "weighed", "at", "each", "time", "point.", "The", "data", "are", "representative", "of", "3", "experiments.", "indicate", "that", "the", "inducibility", "of", "syngeneic", "GVHD", "is", "not", "linked", "to", "the", "MHC", "H-2¢", "haplotype.", "Histology.", "Tissue", "samples", "from", "CsA-treated,", "syngeneic", "hone-", "marrow-reconstituted", "mice", "with", "clinical", "symptoms", "of", "disease,", "as", "well", "as", "diluent", "controls", "and", "normal", "mice", "treated", "with", "CsA,", "were", "examined", "for", "pathologic", "changes.", "Pathologic", "changes", "were", "observed", "in", "the", "large", "intestine,", "spleen,", "and", "thymus", "of", "CsA-", "treated", "animals", "when", "compared", "to", "diluent", "controls.", "In", "general,", "no", "differences", "in", "pathology", "were", "observed", "between", "diluent", "controls", "and", "normal", "mice", "treated", "with", "CsA.", "Consequently,", "only", "the", "data", "from", "the", "diluent", "control", "animals", "are", "represented.", "Although", "the", "observed", "changes", "did", "not", "represent", "the", "full", "range" ]
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505859719_505859723-3.layout.json
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521826392+-6403-11.layout.json
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0060105628-1.layout.json
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508939370_508939517-45.layout.json
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507051678_507051691-7.layout.json
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2046807567_7643-21.layout.json
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524860047+-0116-48.layout.json
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500692166_500692218-2.layout.json
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2028681414.layout.json
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508939370_508939517-141.layout.json
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500170050.layout.json
[ "|", "W", "‘", "Inter-office", "Memorandum", "Subject:", "1,", "§", "M", "TO", "INTRODUCE", "NEW", "LOW", "FLAVOR", "BRAND", "Date:", "geptember", "26,", "1975", "VELLO", "85MM", "To:", "Mr.", "or", "coed,", "TRt", "Wm.", "D.", "Hobbs", "|", "&", "e", "From:", "¢,", "E.", "Miller", "T", "&~", "7/&7/7(", "Division", "Manager", "Cecil", "Bartlett,", "Springfield,", "Mo.,", "has", "given", "us", "the", "following", "information:", "Brand:", "Vello", "Filter", "and", "Menthol", "85mm", "low", "tar", "Date", "of", "Introduction:", "October", "10,", "1975", "Shipping", "case:", "6M", "cases", "Terms:", "3%", "30", "days", "Area", "of", "Introduction:", "14", "counties", "in", "the", "Springfield", "area", "Shipping:", "75", "cases", "6M", "each", "200", "6M", "cases", "of", "20's", "each", ".‘", "Crew", "Work:", "10", "men", "crew", "to", "work", "October", "10", "Sampling", "Employing", "12", "female", "sampling", "representatives", "to", "sample", "giving", "consumers", "2", "packages", "filter", "and", "menthol", "Retail", "Market:", "Consumer", "Market", "Stores", "chain", "of", "25", "stores", "13", "weeks", "$4.00", "per", "store", "per", "week,", "for", "4-", "30", "package", "displays", "NeWspaper:", "40", "newspaper", "ads", "during", "13", "weeks", "Vending:", "1", "full", "carton", "Filter", "and", "Menthol", "placed", "in", "machine", "$1.00", "Filter", "$1.00", "Menthol", "Filter", "If", "both", "in", "machine", "$2.00", "bonus", "Yearly", "payment", "$5.00", "per", "column", "for", "each", "one", "Mr.", "Bartlett", "did", "not", "have", "any", "information", "as", "to", "the", "tar", "and", "picotine", "numbers", "on", "Vello.", "w", "o", "o", ";.", "E.", "%1ller", "\\\\", "3", "o", "TEM:kw", "3", "H.", "Sherrill,", "Jr.", "Mr.", "J.", "F.", "Hind", "Sales", "(2)", "MarkeEihg", "Research", "Department", "o", "cc:", "Mr.", "Colin", "Stokes", "_", "Mr.", "T.", "L.", "Ogburn,", "Jr.", "Mr.", "C.W.", "Fitzgerald", "Mr.", "William", "S.", "Smith", "Mr.", "J.", "H.", "Saylor,", "Jr.", "Mr.", "C.", "C.", "Johnson", "Mr.", "Chas.", "B.", "Wade,", "Jr.", "Mr.", "D.", "W.", "Tredennick", "Mr.", "J.", "B.", "Dempster", "Mr.", "C.", "A.", "Tucker", "Mr.", "G.", "E.", "Harlow", "Marketing", "(2)", "Mr,", "J", "RJRI", "FORM", "2422-Rev.", "7/70" ]
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11300117-0136-12.layout.json
[ "109.", "110.", "111,", "112.", "113.", "114.", "115.", "116.", "117.", "118.", "119.", "120.", "Nicholas,", "H.,", "Pollack,", "C.,", "McCarthy,", "C.,", "O'Connell,", "D.,", "Laguarda,", "R.", "and", "Huber,", "G.:", "The", "effect", "of", "experimentally", "altered", "thyroid", "activity", "on", "alveolar", "macrophage", "function.", "Clin.", "Res.", "21:973,", "1973.", "Sobel,", "K.,", "McCarthy,", "C.,", "Simmons,", "G.,", "Nicholas,", "H.,", "Laguarda,", "R.,", "Mullane,", "J.", "and", "Huber,", "G.:", "Aspiration", "of", "blood.", "Clin.", "Res.", "21:968,", "1973.", "Mullane,", "J.F.,", "Wilfong,", "R.G.,", "Phelps,", "T.0.", "and", "Huber,", "G.L.:", "Dehydration", "and", "factors", "affecting", "pulmonary", "antibacterial", "defenses.", "J.", "Surg.", "Res.", "16:44-49,", "1974,", "Widmann,", "J.J.,", "Nunnemacher,", "G.", "and", "Huber,", "G.L.:", "Ultrastructural", "localization", "of", "catalase", "activity", "in", "the", "pulmonary", "alveolar", "macrophage.", "Fed.", "Proc.", "33:365,", "1974.", "Huber,", "G.,", "Goodenough,", "S.", "and", "O'Connell,", "D.:", "Oxygen", "toxicity", "and", "bacterial", "infection", "in", "the", "lung:", "Impairment", "of", "alveolar", "lining", "material", "versus", "alveolar", "macrophage", "bactericidal", "activity.", "Clin.", "Res.", "22:506,", "1974.", "Parad,", "R.,", "Chou,", "L.,", "Couzens,", "S.", "and", "Huber,", "G.:", "A", "quantitative", "analysis", "of", "recoverable", "and", "in", "situ", "alveolar", "macrophages", "following", "bronchopulmonary", "lavage.", "Clin.", "Res.", "22:401,", "1974,", "Laguarda,", "R.,", "Calihan,", "M.,", "Nyman,", "S.,", "Simmons,", "G.,", "Bempsey,", "T.,", "McCarthy,", "C.", "and", "Huber,", "G.:", "Pulmonary", "infection", "during", "the", "use", "of", "mechanical", "ventilation.", "Clin.", "Res.", "22:508,", "1974.", "McCarthy,", "C.,", "Nicholas,", "H.,", "Pollack,", "C.,", "Simmons,", "G.,", "Laguarda,", "R.", "and", "Huber,", "G.:", "The", "effect", "of", "experimentally", "altered", "thyroid", "activity", "on", "alveolar", "macrophage", "function", "and", "pulmonary", "oxygen", "toxicity.", "Clin.", "Res.", "22:509,", "1974.", "Laguarda,", "R.,", "McCarthy,", "C.,", "Redder,", "D.,", "Goodencugh,", "S.,", "Simmons,", "G.,", "O'Connell,", "D.", "and", "Huber,", "G.:", "Impairment", "of", "in", "vivo", "bacterici-", "dal", "activity", "and", "in", "vitro", "phagocytic", "ability", "of", "pulmonary", "alveolar", "macrophages", "by", "systemic", "steroids.", "Clin.", "Res.", "22:320,", "Goodenough,", "S.,", "Simmons,", "G.,", "Mullane,", "J.,", "Feldman,", "N.", "and", "Huber,", "G.:", "Impairment", "of", "pulmonary", "antibacterial", "defenses", "by", "experimental", "stress.", "Clin.", "Res,", "22:442,", "1974.", "Parad,", "R.,", "Simmons,", "G.,", "Feldman,", "N.", "and", "Huber,", "G.:", "Impairment", "of", "adaptive", "tolerance", "to", "oxygen", "toxicity", "by", "systemic", "immunosuppression.", "Clin.", "Res.", "22:425,", "1974,", "Goodenough,", "S.,", "0'Comnell,", "D.,", "LaForce,", "M.", "and", "Huber,", "G.:", "Aspiration", "versus", "systemic", "absorption", "as", "a", "mechanism", "of", "lung", "injury", "in", "experimental", "kerosene", "pneumonitis.", "Clin.", "Res.", "22:442,", "1974,", "11300129" ]
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513839252_513839291-13.layout.json
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0060199649.layout.json
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2064724569_4570-1.layout.json
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2076716849b_6850-1.layout.json
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0011836357-0.layout.json
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502835948+-5959-10.layout.json
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83364727.layout.json
[ "Patent", "Number", "4m475631824m", "Issue", "Date", "1988", "07", "12", "Appl.", "Data", "791721", "1985", "10", "28", "Assignee", "R.", "J.", "Reynolds", "Tobacco", "Company", "Gentry,", "Thomas", "L.", "Shelar,", "Gary", "R.", "Inventor(s)", "Clearman,", "Jack", "F.", "State/Country", "GA", "Title", "Smoking", "article", "with", "tobacco", "jacket", "Abstract", "The", "present", "invention", "preferably", "relates", "to", "a", "smoking", "article", "which", "is", "capable", "of", "producing", "substantial", "quantities", "of", "aerosol,", "both", "initially", "and", "over", "the", "useful", "life", "of", "the", "product,", "without", "significant", "thermal", "degradation", "of", "the", "aerosol", "former", "and", "without", "the", "presence", "of", "substantial", "pyrolysis", "or", "incomplete", "combustion", "products", "or", "sidestream", "aerosol.", "Preferred", "embodiments", "of", "the", "present", "smoking", "article", "comprise", "a", "short", "combustible", "carbonaceous", "fuel", "element,", "a", "physically", "separate", "aerosol", "generating", "means", "including", "an", "aerosol", "forming", "substance,", "a", "physically", "separate", "tobacco", "jacket", "around", "at", "least", "the", "aerosol", "generating", "means,", "and", "a", "relatively", "long", "mouth", "end", "piece.", "The", "articles", "of", "the", "present", "invention", "provide", "the", "user", "with", "taste,", "feel", "and", "aroma,", "associated", "with", "the¢", "smoking", "of", "conventional", "cigarettes.", "Tobacco", "in", "many", "embodiments", "of", "this", "invention", "is", "burned", "to", "provide", "a", "sidestream", "aroma", "and", "smoke.", "In", "other", "embodiments,", "tobacco", "does", "not", "bura,", "but", "still", "provides", "tobacco", "flavors", "to", "the", "aerosol", "delivered", "to", "the", "user.", "U.S.", "Class", "131/359", "131/196", "131/273", "131/335", "131/360", "IPC", "A24D", "1/18", "A24D", "1/00", "A24D", "1/02", "U.S.", "Refs", "Re27214", "2907686", "3258015", "3356094", "3516417", "3540456", "3614956", "3738374", "3943941", "4044777", "4079742", "4219031", "4284089", "4286604", "4326544", "4340072", "4347855", "4391285", "4474191", "Foreign", "Refs", "AUX", "196507", "276250", "EPX", "198408", "117355", "DEX", "196405", "1294351", "JPX", "000000", "8684/k967", "LRX", "198509", "13985/3890", "GBX", "197003", "1185887", "GBX", "197204", "1431045", "Other", "Refs", "Guinness", "World", "Book", "of", "Records,", "p.", "242-243", "(1985", "Edition).", "Guinness", "World", "Book", "of", "Records,", "p.", "194", "(1966", "Edition).", "Tobacco", "Substitutes,", "Noyes", "Data", "Corporation", "(1976).", "Examiner", "Millin,", "V.", "Agent", "Myers,", "Grover", "M.", "Conlin,", "David", "G.", "(TS", "LIlp9gcg" ]
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2023105194.layout.json
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ton04812.92_ton04812.97-4.layout.json
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10039837_10039839-0.layout.json
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2022161585_2022161648-30.layout.json
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0000066843.layout.json
[ "BROWN", "&", "WILLIAMSON", "TOBACCO", "CORPORATION", "RESEARCH,", "DEVELOPMENT", "&", "ENGINEERING", "INTERNAL", "CORRESPONDENCE", "TO:", "Mr.", "E.", "E.", "Kohnhorst", "cC:", "Mr.", "M.", "L.", "Reynolds", "Mr.", "T.", "F.", "Riehl", "Mr.", "P.", "R.", "Fisher", "Mr.", "R.", "H.", "Honeycutt", "FROM:", "Dr.", "R.", "R.", "Johnson", "DATE:", "December", "5,", "1984", "SUBJECT:", "ADDITIONAL", "GENE-SPLICING", "RESEARCH", "AREA/316", "At", "your", "request,", "I", "have", "given", "thought", "to", "other", "genetic", "engineering", "work", "we", "may", "wish", "to", "sponsor.", "One", "area", "worth", "consideration", "is", "microbial", "production", "of", "tobacco", "terpenoids", "in", "vats.", "What", "would", "be", "most", "useful", "is", "a", "system", "that", "allows", "rapid", "oxidation", "of", "these", "terpenoids", "to", "produce", "the", "same", "flavor", "products", "that", "are", "produced", "by", "slow", "aging", "of", "tobacco.", "There", "are", "three", "classes", "of", "terpenoids", "of", "interest:", "Carotenes", "—", "all", "tobaccos", "Cembranoids", "burley", "and", "flue-cured", "tobaccos", "Labdanoids", "oriental", "tobaccos", "The", "carotenes,", "via", "oxidative", "degradation,", "appear", "to", "make", "the", "largest", "flavor", "contribution", "of", "the", "group.", "Moreover,", "they", "are", "much", "less", "tobacco-specific", "than", "the", "other", "two", "terpenoid", "classes,", "which", "should", "lead", "to", "more", "rapid", "project", "completion.", "R.", "R.", "J.", "RRJ/sek", "08491", "2hYE950S9" ]
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506507005+-7008-0.layout.json
[ "DATE:", "JUL", "20,", "1988", "TEST", "NUMBER:", "CTQO17S", "DATE", "REQUESTED:-840625", "REQUESTED", "BY:", "SELLS,", "R.", "E.", "(4427)", "PROGRAM", "NUMBER:", "7722", "CLASSIFICATION:", "NOW", "KS", "MEN", "TEST", "PURPOSE:", "1984", "COMPETITIVE", "NF0", "EVALUATION", "(WAVE", "III}", "KEYWORD(s):", "BRAND", "NAME:", "FAGE", "1", "5004", "05909" ]
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0001039501-92.layout.json
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501966581_501966587-6.layout.json
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titx0506.90_titx0506.91-1.layout.json
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ton04812.92_ton04812.97-2.layout.json
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530885130+-5136-4.layout.json
[ "Chinese", "Officials", "Plan", "3-Week", "Visit", "Chinese", "officials", "plan", "to", "spend", "three", "weeks", "starting", "August", "25\"", "in", "North", "Carolina", "and", "Virginia’s", "tobacco", "ficlds,", "warchouses", "and", "processing", "plants", "in", "preparation", "for", "U.S.", "leaf", "exports", "to", "China,", "U.S.", "farmers", "and", "exporters", "hope", "that", "the", "visit", "will", "resull", "in", "purchases", "beginning", "as", "early", "as", "December", "1%,", "boosting", "quotas", "for", "the", "next", "scason.", "U.S.", "agriculture", "officials", "announce", "next", "ycar’s", "quotas", "on", "December", "15\",", "Opening", "the", "Chinesce", "market", "to", "U.S,", "leaf", "after", "an", "11-year", "ban,", "reporiedly", "due", "to", "fears", "of", "blue", "mold", "disease,", "could", "mean", "sales", "between", "$70", "million", "to", "$140", "million", "per", "year.", "The", "Sino-U.S.", "tobacco", "trade", "agrecment", "was", "signed", "in", "July", "2000", "afier", "the", "U.S.", "House", "of", "Representatives", "voted", "in", "May", "2000", "to", "extend", "permancnt", "trade", "relations", "(Richmond", "Times-", "Dispatch", "8/22).", "China:", "Seized", "&", "Discounted", "Cigarettes", "Sell", "Briskly", "Sales", "are", "brisk", "at", "shops", "in", "Beijing", "established", "to", "scll", "cigareltes", "seized", "by", "customs", "officials,", "Popular", "brands", "include", "Hilton", "that", "is", "selling", "for", "50", "yuan", "(US$", "6.00)", "a", "carton,", "30", "yuan", "(US$", "3.62)", "less", "than", "the", "market", "value.", "555", "sells", "at", "a", "discounted", "price", "of", "90", "yuan", "(US$", "10.90)", "a", "carlon.", "Other", "available", "brands", "include", "Kent", "and", "More", "(TobaccoChina", "Online", "8/22).", "China:", "Oriental", "Cigarette", "Center", "Planned", "The", "Lli", "prefecture", "will", "launch", "an", "oriental", "cigaretie", "production", "center", "in", "the", "Xinjiang", "Uygur", "Autonomous", "Region", "with", "the", "support", "of", "the", "State", "Tobacco", "Monopoly", "Administration.", "The", "administration", "will", "invest", "10", "million", "yuan", "(US$", "1.21", "mn)", "in", "the", "first", "phase", "to", "build", "three", "or", "four", "oricntal", "cigaretic", "development", "centers", "in", "three", "Lo", "four", "years", "(TobaccoChina", "Online", "8/22).", "innovative,", "information", "technology,", "and", "managerial", "measures", "Lo", "improve", "lcaf", "quality.", "It", "also", "resolved", "to", "take", "steps", "to", "integrate", "industry", "with", "agriculture,", "encourage", "research", "and", "develop", "an", "agricultural", "information", "system", "(TobaccoChina", "Online", "8/22).", "Japan:", "Kanebo", "Gum", "To", "Replace", "Cigarettes", "Kanebo", "Foods", "has", "introduced", "“Kinen", "Scki", "Gum,”", "a", "new", "chewing", "gum", "that", "reportedly", "can", "be", "consumed", "as", "a", "replacement", "for", "smoking", "cigarcttcs.", "The", "gum", "sells", "for", "¥200", "(US$", "1.80)", "for", "five", "picces.", "The", "nicotine-free", "gum", "supposedly", "tastes", "like", "menthol", "cigarettes", "{New", "Food", "Products", "6/00].", "Singapore:", "Smoking", "Control", "Chair", "Opposed", "To", "Banning", "Cigarettes", "Smoking", "Control", "Committee", "chairman", "Alex", "Chan", "does", "not", "support", "banning", "cigarettes", "in", "Singapore", "because", "he", "belicves", "the", "measure", "would", "drive", "the", "business", "underground", "instead", "of", "eliminating", "it.", "Comparing", "cigarettes", "with", "narcotic", "drugs,", "Chan", "said,", "“The", "banning", "of", "hard", "illicit", "drugs", "and", "trendy", "designer", "drugs,", "such", "as", "Ecstasy", "for", "example,", "and", "the", "imposition", "of", "the", "death", "penalty", "for", "trafficking", "have", "not", "stopped", "narcotic", "usage", "totally", "in", "Singapore.”", "In", "1999", "smokers", "in", "Singapore", "spent", "S$", "871", "million", "(US$", "500", "mn)", "consuming", "3.23", "billion", "cigarettes,", "according", "to", "excise", "duty", "collections", "on", "tobacco", "products.", "The", "total", "spending", "on", "smoking", "in", "the", "country", "during", "the", "past", "six", "years", "would", "amount", "to", "S$", "5", "billion", "(US$", "2.91", "bn)", "(Straits", "Times", "8/20).", "Hong", "Kong:", "Yunnan", "To", "Diversify", "Tobacco", "products", "exporter", "Yunnan", "Enterpriscs", "Holdings", "will", "diversify", "into", "biomedical", "and", "information", "technology", "areas", "to", "offset", "its", "falling", "tobacco", "exports,", "according", "to", "the", "company", "chairman", "Zi", "Guorui.", "He", "added", "that", "Yunnan", "plans", "to", "increase", "its", "stake", "in", "Shenzhen", "Xinpeng", "Biotechnology", "Engineering", "Investment", "to", "52", "percent", "from", "the", "current", "48", "percent", "after", "the", "biotech", "company", "successfully", "launches", "high-growth", "technology", "companies", "on", "the", "mainland.", "The", "company", "reported", "a", "net", "profit", "of", "HK$", "757,699", "(US$", "97,100)", "for", "fiscal", "1999-2000", "ended", "March", "31,", "2000,", "compared", "to", "a", "loss", "of", "HK$", "89,626", "(US$", "11,490)", "reported", "during", "the", "previous", "year,", "Turnover", "declined", "from", "HK$", "44", "(Zhongxin", "Network", "8/22),", "million", "(US$", "5.6", "mn)", "last", "year", "to", "HK$", "10.63", "million", "&)", "(US$", "1.4", "mn)", "this", "year", "due", "10", "sluggish", "tobacco", "2", "China:", "Hongta", "Group", "To", "Improve", "Leaf", "exports", "(South", "China", "Morning", "Post", "8/22).", "®", "China;", "Year’s", "Tobacco", "Scene", "Encouraging", "Keeping", "pace", "with", "the", "recovery", "of", "the", "Chinese", "economy", "in", "the", "first", "half", "of", "2000,", "the", "tobacco", "industry", "is", "expected", "to", "contribute", "more", "than", "10", 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503260275_503260278-0.layout.json
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