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D. Michael Miller, Dmitri Maslov and Gerhard W. Dueck
An r -valued m -variable reversible logic function maps each of the rm MVL extensions of the well-known binary T ffoli gates.We analyze the structure of the gates that we use and show h w these gates can be easily simulated in a quantum technology. We present exhaustive results for the 9! 2-variable 3-valued reversible functions comparing the results of our algorithm to optimal results found by breadth-first search.We also show results for specific ternary examples including showing how the presented technique can be applied to the synthesis of a 3-input,3-valued adder which is not itself a reversible problem.When the circuit for the full adder is synthesized, we use it as an example of an approach to a circuit simplification, called the templates tool.Formalization and proper investigation of the templates simplification tool proposed in this paper is still under investigation. |
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I think it is revolutionary for a 18 year old Paul McCartney to write a song about an old person nearing death. This demonstrates that the Beatles did really think about the process of life and its challenges from birth to day in a complete way and the possible answer. Solomon does that too in the Book of Ecclesiastes when he looks at life UNDER THE SUN. I am going to spend two posts looking at this song WHEN I’M SIXTY-FOUR and break it down.
Why did Paul write a song about an old person nearing death called WHEN I’M SIXTY-FOUR in 1961 when he was 18 years old? “When I get older losing my hair…Will you still need me, will you still feed me, When I’m sixty-four?, You’ll be older too…Yours sincerely, wasting away..” Maybe one reason was that he lost his mother at a young age.
Paul’s friend Johnny Cash in 2001 was filmed by the famous photographer Annie Leibovitz (who I am featuring in today’s post). Below I have posted a portion of the article, “From Annie Leibovitz: Life, and Death, Examined,” by JANNY SCOTT, October 6, 2006. The ironic thing to me is that Johnny Cash’s last two song video’s pointed out that Christ is the only answer to the problem of death, pain and suffering and that repentance is the only way to get God’s forgiveness for sin or else you are heading toward a sure judgement. I hope both McCartney and Leibovitz will find that the answer to find meaning in life is found in putting your faith and trust in Jesus Christ. The Bible is true from cover to cover and can be trusted.
King Solomon was the wisest man who ever lived and he said at the end of his life, “The conclusion, when all has been heard, is: fear God and keep His commandments, because this applies to every person. For God will bring every act to judgment, everything which is hidden, whether it is good or evil.”
When I’m Sixty-Four- The Beatles
The song WHEN I’M SIXTY-FOUR appeared on the album SGT. PEPPER’S.” I think that even in the 1960’s when many young people thought they were indestructible the Beatles touched on the subject of death in their songs A DAY IN THE LIFE and WHEN I’M SIXTY-FOUR on the album SGT. PEPPER’S where on the cover there is a scene of the Beatles’ own burial.
How Should We then Live Episode 7
The Beatles – When I’m Sixty-Four
When I’m Sixty-Four
“When I’m Sixty-Four” is a song by the Beatles, written by Paul McCartney[3][4] (credited to Lennon–McCartney) and released in 1967 on their album Sgt. Pepper’s Lonely Hearts Club Band.
Composition[edit]
The song is sung by a young man to his lover, and is about his plans of growing old together with her. Although the theme is ageing, it was one of the first songs McCartney wrote, when he was only 16.[3] It was on the Beatles playlist in their early days as a song to perform when the amplifiers broke down or the electricity went off.[5][6] Both George Martin and Mark Lewisohn speculated that McCartney may have thought of the song when recording began for Sgt. Pepper in December 1966 because his father turned 64 earlier that year.[5][6]
Lennon said of the song, “Paul wrote it in the Cavern days. We just stuck a few more words on it like ‘grandchildren on your knee’ and ‘Vera, Chuck and Dave’ … this was just one that was quite a hit with us.”[7] In his 1980 interview for Playboy he said, “I would never even dream of writing a song like that.”[4]
Instrumentation[edit].”[6] In the song’s final verse, the clarinet is played in harmony with McCartney’s vocal: an unusual method of harmonisation, especially in 1967..[8]
The song is in the key of D-flat major. Recorded in C major, the master take was sped up to raise the key by one semitone at the insistence of McCartney. Martin remembers that McCartney suggested this change to make his voice sound younger.[9] McCartney says, “I wanted to appear younger, but that was just to make it more rooty-tooty; just lift the key because it was starting to sound turgid.”[3]
Release[edit]
The song was nearly released on a single as the B-side of either “Strawberry Fields Forever” or “Penny Lane“, but instead it was decided to put out a double-A-sided-disc of those two and include “When I’m Sixty-Four” on the Sgt. Pepper album.[10]
Cultural references[edit]
-. [13].”
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“When I’m Sixty Four”IaveSend!
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Featured Photographer today is Annie Leibovitz
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John Lennon with a Kodak Instamatic by Annie Leibovitz
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Annie Leibovitz and Jann S. Wenner in the Rolling Stone offices at 625 Third Street in San Francisco. 1973. Photograph by Annie Leibovitz.
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Elizabeth II, Buckingham Palace, London, March 28, 2007. Photograph by Annie Leibovitz.
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Obama Family Portrait Annie Leibovitz
Annie Leibovitz
Anna-Lou “Annie” Leibovitz (/ˈliːbəvɪts/; born October 2, 1949) is an Americanportraitphotographer.
Early life[edit]
Born in Waterbury, Connecticut, on October 2, 1949,[1] Anna-Lou Leibovitz is the third of six children of Marilyn Edith (née Heit) and Samuel Leibovitz.[2] She is a third-generation American; her father’s parents were Romanian Jews.[2] Her mother was a modern dance instructor of EstonianJewish heritage. Her father was a lieutenant colonel in the U.S. Air Force. The family moved frequently with her father’s duty assignments, and she took her first pictures when he was stationed in the Philippines during the Vietnam War.[3]
At Northwood High School,[4] she became interested in various artistic endeavors and began to write and play music. She attended the San Francisco Art Institute,[4] where she studied painting. For several years, she continued to develop her photography skills while holding various jobs, including a stint on a kibbutz in Amir, Israel, for several months in 1969.[5]
Career[edit]
Rolling Stone magazine[edit].[5]
While working for Rolling Stone, Leibovitz became more aware of the other magazines and learned that she could work for magazines and still create personal work, which for her was the most important.[citation needed] She sought intimate moments with her subjects, who “open their hearts and souls and lives to you”. [6]
She was awarded The Royal Photographic Society‘s Centenary Medal and Honorary Fellowship (HonFRPS) in recognition of a sustained, significant contribution to the art of photography in 2009.[citation needed]
Inspirations[edit]
Photographers such as Robert Frank and Henri Cartier-Bresson influenced her during her time at the San Francisco Art Institute. “Their style of personal reportage—taken in a graphic way—was what we were taught to emulate.”[6] Leibovitz has also cited Richard Avedon‘s portraits as an important and powerful example in her life.[citation needed]
The Rolling Stones[edit]
Leibovitz photographed the Rolling Stones in San Francisco in 1971 and 1972, and served as the concert-tour photographer for Rolling Stones Tour of the Americas ’75. Her favorite photo from the tour was a photo of Mick Jagger in an elevator.[7]
Joan Armatrading[edit]
In 1978 Leibovitz became the first woman to photograph Joan Armatrading for an album. She did the photography for Armatrading’s fifth studio album To the Limit, spending four days at her house capturing the images.[8] Liebovitz also did the photography for Armatrading’s live album, Steppin’ Out.[citation needed]
John Lennon[edit]
On December 8, 1980, Leibovitz had a photo shoot with John Lennon for Rolling Stone, and she promised him he would make the cover.[9] She had initially tried to get a picture with just Lennon alone, as Rolling Stone wanted, but Lennon insisted that both he and Yoko Ono be on the cover. Leibovitz then tried to re-create something like the kissing scene from the couple’s Double Fantasy1980 album cover, a picture Liebovitz loved, and she had John remove his clothes and curl up next to Yoko on the floor. Leibovitz recalls, “What is interesting is she said she’d take her top off and I said, ‘Leave everything on’ — not really preconceiving the picture at all..”[10] Leibovitz was the last person to professionally photograph Lennon—he was shot and killed five hours later.[11]
The photograph was subsequently re-created in 2009 by John and Yoko’s son Sean Lennon, posing with his girlfriend Charlotte Kemp Muhl, with male/female roles reversed (Sean clothed, Kemp naked),[12][13] and by Henry Bond and Sam Taylor-Wood in their YBA pastiche October 26, 1993.[14]
In 2011, Leibovitz was nominated alongside Singaporean photographer Dominic Khoo and Wing Shya for Asia Pacific Photographer of the Year.[citation needed]
Other projects[edit]
- In the 1980s, Leibovitz’s new style of lighting and use of bold colors and poses got her a position with Vanity Fair magazine.[15]
- Leibovitz photographed celebrities for an international advertising campaign for American Expresscharge cards, which won a Clio award in 1987.[citation needed]
- In 1991, Leibovitz mounted an exhibition at the National Portrait Gallery. She was the second living portraitist and first woman to show there.[11]
- In 1991, Leibovitz had been made Commandeur de l’Ordre des Arts et des Lettres by the French Government.[11]
- Also in 1991, Leibovitz emulated Margaret Bourke-White‘s feat by mounting one of the eagle gargoyles on the 61st floor of the Chrysler Building in Manhattan, where she photographed the dancer David Parsons cavorting on another eaglegargoyle. Noted Life photographer and picture editor John Loengard made a gripping photo of Leibovitz at the climax of her danger. (Loengard was photographing Leibovitz for The New York Times that day).[citation needed]
- In 2007, major retrospective of Leibovitz’s work was held at the Brooklyn Museum,[16].[17] The show included 200 photographs.[18] At the exhibition, Leibovitz showed that she doesn’t have two lives, career and personal, but has one wherein assignments and personal pictures are all part of her works. This exhibition and her talk focused on her personal photographs and life.[citation needed]
- In 2007, The BBC misrepresented Leibovitz’s portrait shooting.”[19] The BBC later apologized and admitted that the sequence of events had been misrepresented, as the Queen was in fact walking to the sitting in the second scene.[20] This led to a BBC scandal and a shake-up of ethics training.
- In 2007, The Walt Disney Company hired her to do a series of photographs with celebrities in various roles and scenes for the Walt Disney Parks and Resorts “Year of a Million Dreams” campaign.[21][22] Leibovitz claims she never liked the word “celebrity”. “I’ve always been more interested in what they do than who they are, I hope that my photographs reflect that.” She tries to receive a little piece of each subject’s personality in the photos.[6]
- On April 25, 2008, Entertainment Tonight reported that 15-year-old Miley Cyrus had posed topless for a photo shoot with Vanity Fair.[23][24] The photograph and subsequently released behind-the-scenes photographs show Cyrus topless, her bare back exposed but her front covered with a bedsheet. The photo was taken by Leibovitz.[25] The full photograph was published with an accompanying story on The New York Times‘ website on April 27, 2008. On April 29, 2008,The New York Times clarified: though the pictures left an impression that she was bare-breasted, Cyrus was wrapped in a bedsheet and was actually not topless.[26] Some parents expressed outrage at the nature of the photograph, which a Disney spokesperson described as “a situation [that] was created to deliberately manipulate a 15-year-old in order to sell magazines”.[26].”[26]
Leibovitz also released a statement saying:
“I’m sorry that my portrait of Miley has been misinterpreted. … The photograph is a simple, classic portrait, shot with very little makeup, and I think it is very beautiful.”[26][27]
- In October 2011, Leibovitz had an exhibit in Moscow. In an interview with Rossiya 24, she explained her photography style.[28]
- In 2014, the New-York Historical Society mounted an exhibit of Leibovitz’s work, based on her 2011 book, Pilgrimages.[29]
Archive[edit]
Since 1977, Leibovitz licensing images have been represented by Contact Press Images, a photojournalism agency based in New York City. She ceased to be represented by Jim Moffat at A Corporation for Art & Commerce in 2009.
Personal life[edit]
Children[edit]
Leibovitz has three children. Her daughter Sarah Cameron Leibovitz was born in October 2001 when Leibovitz was 52 years old.[30] Her twins (two girls), Susan and Samuelle, were born to a surrogate mother in May 2005.[31]
Susan Sontag by Annie Leibovitz
Relationships[edit]
Leibovitz had a close relationship with writer and essayist Susan Sontag from 1989 until Sontag’s death in 2004. During Sontag’s lifetime, neither woman publicly disclosed whether the relationship was a platonic friendship or romantic.Newsweek in 2006 made reference to Leibovitz’s decade-plus relationship with Sontag, stating, “The two first met in the late ’80s, when Leibovitz photographed her for a book jacket. They never lived together, though they each had an apartment within view of the other’s.”[32] Leibovitz, when interviewed for her autobiography A Photographer’s Life: 1990-2005 (2006 in literature|2006), said the book told a number of stories, and “with Susan, it was a love story.”[33] While The New York Times in 2009 referred to Sontag as Leibovitz’s “companion”,[34] Leibovitz wrote in A Photographer’s Life that, “Words like ‘companion’ and ‘partner’ were not in our vocabulary. We were two people who helped each other through our lives. The closest word is still ‘friend.'” [35] That same year, Leibovitz said the descriptor “lover” was accurate.[36] She later reiterated, “Call us ‘lovers’. I like ‘lovers.’ You know, ‘lovers’ sounds romantic. I mean, I want to be perfectly clear. I love Susan.”[31]
Religion[edit]
Despite being raised in a Jewish home, Leibovitz no longer practices Judaism. When asked if being Jewish is important to her, Leibovitz replied, “I’m not a practicing Jew, but I feel very Jewish.”[2]
(Image Credit: Merce Cunningham. Photo Annie Leibovitz)
Examples of Leibovitz’s photographs[edit]
- John Lennon and Yoko Ono for the Jan. 22, 1981, Rolling Stone cover, taken the day Lennon was murdered.[47][48]
- Prisoners at Soledad State Prison in California, each hugging a visiting family member, with each couple standing a few feet from the next, taken on Christmas 1971.
- Linda Ronstadt in a red slip, on her bed, reaching for a glass of water in a 1976 cover story for Rolling Stone magazine.[49]
- Demi Moore has been the subject of two highly publicized Vanity Fair covers taken by Leibovitz: More Demi Moore (Aug. 1991) featuring Moore pregnant and nude, and Demi’s Birthday Suit (Aug 1992), showing Moore nude with a suit painted on her body.[50]
- Marion Cotillard for the Autumn/Winter 2009 collection of the Lady Dior – Lady Rouge handbag campaign[51] and for the November 2009 cover of Vogue with the cast of Nine.[52]
- Fleetwood Mac for a 1977 issue of Rolling Stone magazine. Stevie Nicks and Mick Fleetwood are shown lying together, as are Christine McVie and Lindsey Buckingham at the opposite end of the bed. John McVie is shown reading Playboy magazine.[53]
- Whoopi Goldberg lying in a bathtub full of milk, shot from above.[54]
- Christo, fully wrapped so the viewer must take the artist’s word that Christo is actually under the wrapping.[55]
- David Cassidy on the Rolling Stone cover depicting him naked from his head to his waist.
- Dolly Parton vamping for the camera while Arnold Schwarzenegger flexes his biceps behind her, featured in an August 25, 1977, Rolling Stone photo spread.[56]
- Dan Aykroyd and John Belushi as The Blues Brothers, with their faces painted blue.[57]
- Keira Knightley and Scarlett Johansson, both nude, with a fully clothed Tom Ford, for the cover of Vanity Fair ’s March 2006 Hollywood Issue.[58]<
- Knut with Leonardo DiCaprio, a 2007 Vanity Fair cover.[59]
- Queen Elizabeth II on occasion of her state visit in United States in 2007.[60]
- Jackie and Joan Collins in a limo, Los Angeles 1987.[61]
- Sting, with whom she shares a birthday, naked in the desert, covered in mud to blend in with the scenery.[62]
- Closeup portrait of Pete Townshend framed by his bleeding hand dripping real blood down the side of his face.[63]
- “Fire” portrait and caption “Patti Smith Catches Fire.”[64][65]
- Cyndi Lauper, She’s So Unusual and True Colorsalbum covers[66][67]
- Bruce Springsteen, Born in the U.S.A. and Tunnel of Love album cover.[68][69]
- Gisele Bündchen and LeBron James on the April 2008 cover of Vogue America.[70][71]
- Miley Cyrus‘ Vanity Fair photo in which the child star appeared semi-nude, leading to a controversy.
- Michael Jackson twice for the cover of Vanity Fair magazine, including other additional photographs of him that were not featured on the cover of the magazine.
- Bill Gates for the cover of Gates’ book “The Road Ahead.”
- Family of Barack Obama in the White House.[72]
- Johnny Depp and Kate Moss at the Royalton Hotel, New York in 1994. A nude Moss laying on a bed while fully clothed Depp is lying between her legs, covering her abdomen.
- Lance Armstrong riding his Trek Madone bicycle in the buff in the rain. It was shown in Vanity Fair ’s 1999 December issue.
- Lady Gaga for Vogue and Vanity Fair
- Rihanna for Vogue in 2011 and 2012.
- The cast of Les Misérables (Hugh Jackman, Russell Crowe, Anne Hathaway, Amanda Seyfried, Eddie Redmayne, Helena Bonham Carter and Sacha Baron Cohen) for Vogue in 2012.
- Benedict Cumberbatch for Vogue in 2013[73]
- Kim Kardashian, Kanye West and their daughter North for Vogue in 2014.[74]
- Dane DeHaan for Prada
- Amy Van Dyken posing underwater with a milk mustache as part of the 1996 Milk Mustache campaign.
- The cast of Star Wars: The Force Awakens for Vanity Fair in 2015.
Johnny Cash & Family by Annie Leibovitz, 2001
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Tuesday, October 12, 2010
Annie Leibovitz – Some of my favorites
Nicole Kidman
Appreciation Station { Annie Leibovitz }
This. |
Effects of Tocilizumab Therapy on Serum Interleukin-33 and Interleukin-6 Levels in Patients With Rheumatoid Arthritis
In Ah CHOI1, Sang Jin LEE2, Won PARK3, Sung Hwan PARK4, Seung-cheol SHIM5, Han Joo BAEK6, Dae-Hyun YOO7, Hyun Ah KIM8, Soo Kon LEE9, Yun Jong LEE10, Young Eun PARK11, Hoon-Suk CHA12, Eun Young LEE13, Eun Bong LEE13, Yeong Wook SONG2
1Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, South Korea
2Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Medical Research Institute, Seoul National University, Seoul, South Korea
3Department of Internal Medicine, Inha University Hospital, Incheon, South Korea
4Department of Internal Medicine, The Catholic University of Korea Seoul St. Mary’s Hospital, Seoul, South Korea
5Department of Internal Medicine, Chungnam National University Hospital, Daejeon, South Korea
6Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea
7Department of Internal Medicine, Hanyang University Medical Center, Seoul, South Korea
8Department of Internal Medicine, Hallym University Medical Center, Anyang, South Korea
9Department of Internal Medicine, CHA Bundang Medical Center, Seongnam, South Korea
10Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
11Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea
12Department of Internal Medicine, Sam Sung Medical Center, Seoul, Seoul, South Korea
13Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea
Keywords: Arthritis, interleukin-6, interleukin-33, rheumatoid, tocilizumab
Abstract
Objectives: This study aims to examine the effects of tocilizumab therapy on serum levels of interleukin (IL)-33 and IL-6 in rheumatoid arthritis (RA) patients.
Patients and methods: Interleukin-33 and IL-6 levels in serum samples from 83 RA patients (10 males, 73 females; mean age 51.9 years; range, 26 to 77 years) and 12 healthy controls (2 males, 10 females; mean age 52.2 years; range, 39 to 62 years) were compared by cross-sectional, case control analysis. Of the RA patients, 40 received 24 weeks of tocilizumab therapy and were assigned to the prospective cohort. These 40 patients were then divided into two subgroups as responders and non-responders according to the American College of Rheumatology (ACR) 20. The remaining 43 RA patients did not receive tocilizumab therapy. Serum cytokine levels were analyzed at baseline and after 24 weeks of tocilizumab therapy in these patients.
Results: Interleukin-33 and IL-6 concentrations were significantly higher in RA patients than in healthy controls (p<0.001 for both). Serum IL-33 levels in RA patients showed a significant correlation with rheumatoid factor titer (r=0.660, p<0.001), and IL-6 levels showed a significant correlation with high-sensitivity C-reactive protein levels (Spearman's rank correlation coefficient=0.482, p<0.001). Serum IL-33 levels decreased significantly after 24 weeks of tocilizumab therapy (p<0.001); this was particularly marked in ACR20 responders (p<0.001). However, the decrease in non-responders was not significant (p=0.066). Changes in serum IL-6 levels after 24 weeks of tocilizumab therapy were not significant in either ACR20 responders or non-responders.
Conclusion: Serum IL-33 levels in RA patients receiving tocilizumab therapy decreased significantly, particularly in ACR20 responders. Thus, IL-33 may be a useful marker for monitoring responses to tocilizumab therapy.
Introduction
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the synovial joints, which results in cartilage and bone destruction. Several pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF)-α, interleukin (IL)-1, IL-6, IL-8, and IL-15 are critical for synovial inflammation in RA,(1,2) indeed, treating RA by targeting pro-inflammatory cytokines, including TNF-α, IL-1, and IL-6, has met with some success.(3-5)
Interleukin-33 is a newly described member of the IL-1 family and was identified as a ligand for the orphan receptor growth STimulation expressed gene 2 (ST 2). It plays a role in allergic diseases by activating mast cells and promotes T helper type 2 immune responses.(6,7) IL-33 levels in RA patients are higher than those in healthy controls, and synovial expression of IL-33 is greater in RA than in osteoarthritis, suggesting that IL-33 may be involved in the pathogenesis of RA.(8,9) In addition, blocking IL-33 ameliorates joint inflammation and destruction in mice with collagen-induced arthritis (CIA).(10,11)
A previous study has shown that serum levels of IL-33 correlate with those of IL-6 in RA patients.(8) However, to our knowledge, no study has examined serum IL-33 levels in RA patients receiving IL-6 receptor (IL-6R) inhibitor therapy. Therefore, in this study, we aimed to examine the effects of tocilizumab therapy on serum levels of IL-33 and IL-6 in RA patients.
Patients and Methods
We performed a cross-sectional, case control analysis of serum IL-33 and IL-6 levels in 83 patients with RA (10 males, 73 females; mean age 51.9 years; range, 26 to 77 years) and 12 healthy controls (2 males, 10 females; mean age 52.2 years; range, 39 to 62 years) at participating hospitals between September 2009 and December 2010. Of the RA patients, 40 were treated with an intravenous infusion of 8 mg/kg tocilizumab every four weeks for 24 weeks with a stable dose of methotrexate and/or other disease- modifying anti-rheumatic drugs. Therefore, these 40 RA patients were considered the prospective cohort. The 40 patients were then divided into two subgroups as responders and non- responders according to the American College of Rheumatology (ACR) 20. The remaining 43 RA patients did not receive tocilizumab therapy.The study protocol was approved by the Seoul National University Hospital Ethics Committee (C-1302-028-463). A written informed consent was obtained from each patient. The study was conducted in accordance with the principles of the Declaration of Helsinki.
Serum samples were promptly stored at -80°C until the time of cytokine assay. Samples from the 40 patients that received tocilizumab were obtained at two time points: at baseline and 24 weeks after the initial dose was given. Clinical scores and laboratory assay results, including the erythrocyte sedimentation rate (ESR), high- sensitivity C-reactive protein (hsCRP) level, serum rheumatoid factor (RF) level, and disease activity score of 28 joints including the ESR (DAS28-ESR), were obtained at the same time points.
Interleukin-33 was measured using a bead immunoassay and Luminex laser-based fluorescent analytical test instrumentation (Merck-Millipore, Merck KGaA, Darmstadt, Germany). Serum IL-6 and RF were assayed using enzyme linked immunosorbent assay (ELISA) (IL-6, eBioscience, San Diego, CA, USA and RF, Nittobo, Tokyo, Japan). All assays were conducted in duplicate.
Statistical analysis
Data are expressed as the mean±standard deviation or median (range) as appropriate. The Mann-Whitney U test was used for group comparisons and the Wilcoxon signed rank test for paired comparisons. Single regression analysis was performed to examine the relationship between serum IL-33 levels and clinical laboratory parameters, and Spearman’s rank correlation coefficients were calculated. The Wilcoxon signed rank test was used to compare values measured before and after tocilizumab therapy. P values <0.05 were considered significant. All statistical analyses were performed using IBM SPSS statistics version 22.0 (IBM Corp., Armonk, NY, USA), and the graphics were generated in GraphPad Prism version 5 (GraphPad, La Jolla, CA, USA).
Results
The baseline
characteristics of 83 RA patients and 12 healthy controls were listed in Table 1. The concentrations of IL-33 and IL-6 were significantly higher in patients with RA than in controls (p<0.001 for both; Figure 1). The median IL-33 level for RA patients was 18.37 pg/mL (range, 0.0-4364.2 pg/mL), whereas that for the controls was 0 pg/mL (range, 0.0-15.97 pg/mL). The median IL-6 levels were 8.4 pg/mL (range, 0.6-20 pg/mL) and 1.25 pg/mL (range, 0.3-2.9 pg/mL), respectively.
We examined the relationship between serum IL-33 or IL-6 levels and RA characteristics at baseline in all 83 RA patients. IL-33 levels showed a significant correlation with RF titer (Spearman's rank correlation coefficient [rho]=0.660, p<0.001), but not with DAS28 (rho=0.122, p=0.271), ESR (rho=0.177, p=0.110), hsCRP (rho=0.151, p=0.174), or RA duration (rho=0.121, p=0.274). IL-6 levels showed a significant correlation with hsCRP (rho=0.482, p<0.001), but not with DAS28 (rho=0.204, p=0.065), ESR (rho=0.104, p=0.351), RF titer (rho= -0.028, p=0.805), or RA duration (rho= -0.170, p=0.124). There was no correlation between serum IL-6 and IL-33 levels (rho=0.012, p=0.913).
We compared serum IL-33 levels in 40 RA patients before and after tocilizumab therapy. The results showed that serum IL-33 levels decreased significantly after 24 weeks of tocilizumab (median 77.0 pg/mL down to median 11.9 pg/mL, p<0.001; Figure 2a). There was no difference in serum IL-6 levels at baseline and those after 24 weeks of tocilizumab therapy (median 7.1 and 8.9 pg/mL, respectively, p=0.503; Figure 2b). Serum IL-33 levels in ACR20 responders decreased significantly after 24 weeks of tocilizumab therapy (median 109.0 to median 15.8 pg/mL, n=29; p<0.001); this decrease was not significant in non-responders (median 35.5 to 12.1 pg/mL, n=11, p=0.084). Changes in IL-6 levels in ACR20 responders (6.9 to 7.2 pg/mL, p=0.477) and non- responders (8.7 to 10.6 pg/mL, p=0.665) between baseline and 24 weeks after tocilizumab therapy were not significant. Baseline IL-33 levels in the two subgroups were not significantly different (p=0.765; Figure 3a). The same was true for IL-6 (p=0.267; Figure 3b).
Discussion
Serum IL-33 and IL-6 concentrations in patients with RA were significantly higher than those in healthy controls. The significant correlation between IL-33 and RF titer suggests that production of the former might be linked to autoantibodies in these patients. IL-33 enhances mast cell activation by immunoglobulin G,(12) as well as inducing human mast cells to release immunomodulatory mediators such as IL-10 and histamine along with other cytokines associated with type 2 immune responses, such as IL-5 and IL-13. IL-33 primes mast cells toward a Th2/immunomodulatory phenotype, a phenotype that becomes more prominent after concomitant activation of mast cells by immunoglobulin G.(12)
Like the majority of IL-1 family members that act as pro-inflammatory cytokines, IL-33 is expected to promote inflammation in RA.(13) Studies of mice with CIA suggest that inhibiting the IL-33 receptor may have therapeutic effects similar to IL-1 inhibition therapy for RA.(14) However, we found no correlation between the IL-33 concentrations and markers of RA disease activity (i.e., the DAS28, ESR, or hsCRP). The link between IL-33 and inflammation in RA may be indirect, and IL-33 levels could be affected by other cytokine cascades such as TNF-α or IL-6. TNF-α stimulates production of IL-33 by synovial fibroblasts,(15) and IL-33 levels decrease after infliximab and etanercept therapy.(16,17) In addition, overexpression of IL-33 increases TNF-α-induced IL-6 secretion by RA-synovial fibroblasts, and IL-33 silencing significantly down-regulates TNF-α-induced IL-6 secretion in vitro.(10) However, we detected no direct correlation between serum IL-6 and IL-33 levels in this study. We did find that IL-33 levels showed a high degree of inter-individual variability, which may (at least in part) account for discrepancies regarding the correlation between serum IL-33 concentrations and RA disease activity.(16-18)
There are several limitations in this study. Because only 40 patients received tocilizumab therapy and the majority showed a favorable response to tocilizumab therapy, the sample size of non-responders was too small (n=11). The sample size of healthy controls was also too small to provide a precise match in age and sex with RA patients.
However, to the best of our knowledge, this study is the first to examine serum IL-33 concentrations both before and after tocilizumab therapy. Although the sample size was small, all patients received a stable dose of methotrexate and/or other disease-modifying anti-rheumatic drugs, and we observed a relatively long term response after 24 weeks of therapy. Unfortunately, we did not analyze radiologic progression and therefore cannot present results showing a correlation between IL-33 and joint damage. This is another limitation of this study.
In conclusion, our results revealed that serum levels of IL-33 did not correlate with IL-6 levels. In addition, treatment with an IL-6R inhibitor did not change serum IL-6 levels; rather, it reduced serum IL-33 levels. It is interesting that even in ACR20 responders with decreased ESR and CRP levels, the pro-inflammatory cytokine IL-6 level did not change significantly in the present study. There was a previous report showing that serum IL-6 concentrations are increased after administration of tocilizumab in both healthy volunteers and RA patients and suggesting that free serum IL-6 is increased after tocilizumab therapy because IL-6R-mediated consumption of IL-6 was inhibited by the unavailability of tocilizumab-free IL-6R.(19) Taken together, it is not possible at the present time to explain the response to tocilizumab therapy in terms of serum IL-6 levels; therefore, IL-33 may be a useful indicator of responses to tocilizumab therapy.
Citation: Choi IA, Lee SJ, Park W, Park SH, Shim SC, Baek HJ. Effects of tocilizumab therapy on serum interleukin-33 and interleukin-6 levels in patients with rheumatoid arthritis. Arch Rheumatol 2018;33(4):389-394.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
This research was supported by grants from the Ministry of Science, ICT and Future Planning, Republic of Korea (NRF-2015M3A9B6052011) and the Korea Healthcare technology R&D Project, Ministry of Health and Welfare, Republic of Korea (HI14C1277), and partly by a grant from JW Pharmaceuticals.
References
- McInnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 2007;7:429-42.
-.
- Cohen SB, Moreland LW, Cush JJ, Greenwald MW, Block S, Shergy-8.
- Fleischmann RM, Halland AM, Brzosko M, Burgos- Vargas R, Mela C, Vernon E, et al. Tocilizumab inhibits structural joint damage and improves physical function in patients with rheumatoid arthritis and inadequate responses to methotrexate: LITHE study 2-year results. J Rheumatol 2013;40:113-26.
- Liew FY, Pitman NI, McInnes IB. Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol 2010;10:103-10.
- Miller AM. Role of IL-33 in inflammation and disease. J Inflamm (Lond) 2011;8:22.
-:32-7.
- Leung BP, Xu D, Culshaw S, McInnes IB, Liew FY. A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. J Immunol 2004;173:145-50.
- Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, et al. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 2009;60:738-49.
- 2015;67:2343-53.
- Barksby HE, Lea SR, Preshaw PM, Taylor JJ. The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin Exp Immunol 2007;149:217-25.
- Zhao Q, Chen G. Role of IL-33 and its receptor in T cell-mediated autoimmune diseases. Biomed Res Int 2014;2014:587376.
- Kunisch E, Chakilam S, Gandesiri M, Kinne RW. IL-33 regulates TNF-a dependent effects in synovial fibroblasts. Int J Mol Med 2012;29:530-40.
- Mu R, Huang HQ, Li YH, Li C, Ye H, Li ZG. Elevated serum interleukin 33 is associated with autoantibody production in patients with rheumatoid arthritis. J Rheumatol 2010;37:2006-13.
- Kageyama Y, Torikai E, Tsujimura K, Kobayashi M. Involvement of IL-33 in the pathogenesis of rheumatoid arthritis: the effect of etanercept on the serum levels of IL-33. Mod Rheumatol 2012;22:89-93.
- Tang S, Huang H, Hu F, Zhou W, Guo J, Jiang H, et al. Increased IL-33 in synovial fluid and paired serum is associated with disease activity and autoantibodies in rheumatoid arthritis. Clin Dev Immunol 2013;2013:985301.
--64. |
By Tony Turner
May 1, 2019.
“I started working with professors and their Ph.D. students my first semester at State,” said Chaney, biology grad student of Spencer, Ind. “These opportunities wouldn’t have been possible at other Indiana universities with over 40k students. I’ve had almost six years of hands-on experience in a department that has watched me develop as a student, biologist, and mentor.”
During her first year at State, she started getting involved on campus through the Student Government Association’s Student Leadership Coalition. The following year she became a senator for the Student Government Association for two years. During her second year, she was the Academic Affairs Committee chair. She also joined the National Society of Leadership and Success in her junior year of undergrad.
“As an undergraduate in the biology department joined TriBeta, which is a national biological honor society, participated in the Summer Undergraduate Research Experience,” said Chaney. “I worked in professor Tuttle and professor Gonser’s lab as a research technician, and spent a summer working on the sparrow project in upstate New York as a field assistant.”
Involvement in the biology department helped Chaney make an easy decision to attend State for grad school.
“I primarily chose Indiana State for graduate school because it was close to home. Since I did my undergrad here I knew what State had to offer and I knew how to get the most out of my degree,” said Chaney.
“As a graduate student, I have been the treasurer of the Biology Graduate Student Association since its formation in spring 2018,” said Chaney. “I was also the planning committee chair for the Midwest Ecology and Evolution Conference, hosted at State in April 2019. The conference turned out to be a huge success for both the department and for ISU. There were over 100 students from 12 states in attendance. Many of the students that attended are looking for graduate school opportunities so I hope we were able to put State on the map. It was a great weekend and our graduate students put in a lot of effort to have this conference go off without a hitch..”
The Biology Graduate Student Association serves as the official platform for biology graduate students.
“We help students voice their concerns and channel it through the appropriate avenues,” said Chaney. “We also host social events throughout the year to try and keep the department’s students in good spirits. It’s hard to stay connected since we’re divided into different lab so we offer a focal point where biology grad students can get together as a group.”
After two years of grad school, Chaney has learned a lot about herself and what it takes to succeed in achieving her second degree.
“You’re responsible for your own success,” said Chaney. “You can’t expect someone to take the initiative for you so on days you put 10 percent in, expect to get 10 percent back.”
Chaney has interviewed at multiple schools for a PhD position in ecology.
“So far, I have interviewed at the University of Wisconsin – Madison, University of Missouri – St. Louis, Purdue University, and Western Michigan University. I have received multiple offers, but I have chosen to start a PhD at Purdue University in the fall,” said Chaney. |
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PLEASE REVIEW THESE LOAN EXAMPLES 1). Example 40M (Direct Debt) Loan amount: $40,000,000.00Initial deposit: $1,400,000.00Loan payments: $62,086,665.64Total payable: $63,486,665.64300 monthly…Continue
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300 monthly payments of: $206,955.55 / Annually $ 2,483,466.60
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Start date: June 15, 2015
End date: June 15, 2040
Extra fees: TBA
Interest Rate: 4.15%
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By Timothy Seidel
PalestineChronicle.com strangulating,” that is that western segregation zone between the Wall and the Green Line which includes roughly 11 percent of the West Bank and that ‘Pal...
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About Me
28 year-old Judge Tommy from Fort Saskatchewan, has many passions that include jewellery, . and flower arranging. Has completed a fantastic round the world voyage that consisted of going to the Sceilg MhichÃl.
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Chess
by John
I have been teaching my 5 year old grandsons to play chess. It started with checkers, but the little buggers are already beating me at that! So I have upped the ante and introduced chess.
Then I thought that a chess set might make a nice present. So I explored THINGIVERSE and found these Egyptian styled pieces. Free download. And I have been printing them. I intend to cast them in bronze and aluminium.
The detail and quality of these Thingiverse STL’s is superb!
I am printing in 0.15mm layers, using PLA.
Quite excited about this project.
So, when they start beating you at Chess. What then???
Perhaps Cast Brass for one set,(Black) aluminium the other, (white). Al might be a bit light so a set in copper/bronze??
Interested to see the outcome either way.
Your chess set looks fabulous! Can’t wait to see the castings!
thanks Richard! I too am quite excited about this one. |
안녕하세요! Which means hello! Today I’m sharing a super sweet and yummy snack that I found.
Gimme anything that is cake batter, birthday cake, or cake related. I’ll take it!
Peeps Cake Party has the same consistency and flavor of original Peeps, with the added bonus of cake flavor and sprinkle confetti that crunches as you eat. Super soft marshmallow with crunchy bits… 🤤
Yum!
After the smooshy crunchy first bite, you get a flavorful mouthful of cake! Yep! These taste just like birthday party cake, and they are soooo good!
These are GOOD GOOD GOOD!
This and all the candy I purchase comes from the local Dollar Tree. They have the best candy (my local Big Lots was a let-down) and the best prices. Maybe you can find similar quality and deals at WalMart. I think it all depends on your area.
That’s it for today! 🍭
안녕! Bye! Ciao!
jarilissima
Peeps are kinda divisive. You either really like them or hate them. Very little in between.
LikeLiked by 3 people
Never ate those.
LikeLiked by 2 people
I think they were seasonal. Haven’t been able to find them again, but they were very good 🙂 Thanks for all the likes and comments!
LikeLiked by 1 person
You are very welcome!
LikeLiked by 2 people |
.
So quite contrary to providing a windfall to the banks, GSE participation in this program would force them to help homeowners even further by writing down these second lien loans.
In addition to clarifying this misconception, though, it is important to take a step back and appreciate the broader impact that GSE participation in this program would have. It would be an important tool in helping put deeply underwater homeowners back on a more sustainable path with their mortgage, lowering the chances that they have to hand in the keys and walk away from their homes. Moreover, it will help stabilize communities and minimize losses to the GSEs and the taxpayer. As Secretary Geithner has said, principal reduction is by no means the solution for all borrowers struggling to pay their bills, or even all who struggle with negative equity. But it is smart economic policy for some, and where it is we should provide that help.
Michael Stegman is Counselor to the Secretary of the Treasury for Housing Finance Policy.
Treasury Secretary Jacob J. Lew delivered remarks on currency redesign at the National Archives Thursday, June 18, 2015. Secretary Lew's remarks expanded on his decision to redesign the $10 note.
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In need of this New Jersey band's No Frills 1986 demo. Need its lineup, and that of their 1988 demo, You've Been Warned.
Tuesday, December 20, 2011
Brute Force
Posted by Robert Plante at 5:48 PM
This blog exists to help locate information and audio for the forthcoming book DemoLition, a complete-as-possible guide to all known heavy metal and hard rock demos released in the 1980s, tentatively scheduled for a 2018 release.
The 88 cassette EP was released by BDF Records (run by CJ Scioscia from Insaniac). I've still got a copy but I'll send a message to CJ for you.
I have the 88 one, but I just need the lineup for it, thanks! |
According to the U.S. Census Bureau Data, a full year since the Affordable Care Act has come into play, the[…]Read more
Author: WellAway
What Medicare’s Value-based Insurance Test Could Mean for Commercial Plans
The Latest Fit Tech From the Consumer Electronics Show (CES)
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The IRS Moves Towards Implementing the Cadillac Tax
Anthem Purchases Cigna Creating Risks and Opportunities in the Health Insurance Industry
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, or if yesterday’s dreams no longer motivate you nor anyone else, you a fantastic week from all of us at makeadreamng.com
One thought on “Get A ‘Dream Upgrade’… By Funmi Adebayo”
Reblogged this on Funmi Adebayo's Blog and commented:
Here’s our editor’s note from makeadreamng.com . The keyword for the week is UPGRADE! Enjoy it! Have a beautiful week ahead |
I made it out to the garden this morning and found that the garden doesn't care whether I visit regularly or not. Stuff just keeps growing and growing without me. I cut one of the smaller giant zukes up into strips, dipped the strips in tempura batter and deep fried them. I haven't deep fried anything since I started weight watchers five years ago. Man, they were yummy! I'm not sure what I'm going to do with all those cucumbers, though. I'll put them in the teacher's lounge tomorrow. Every teacher knows that the lounge is like the black hole for food. I once put a nine-by-thirteen pan of Mom's pistachio dessert out before school started and that sucker was gone by first recess. It looked like they had licked the pan. I bet the cucumbers don't go that fast, though.
Anyone have a recipe that calls for humongous zucchini? I can't let them go to waste since it was my beginning-of-the-school-year neglect that made them like this. I'm personally responsible. When I first saw them out there this morning I felt actual guilt. Like some mad scientist experimenting in zucchini deformity. My conscience won't allow me to make fried zucchini every night this week and we've had more than enough zucchini bread this summer. I don't think they'll be good sauteed, but I guess I could try it. I could send zucchini sticks in Munchkin's backpack for snack (but he'd probably disown me). I thought about entering them for a giant zucchini prize in the county fair, but we don't have a fair, here. Can you use them to carve jack 'o lanterns? I promise to garden responsibly from now on.
4 comments:
Love the vegetables! Mine didn't fair as well! God Bless, Melissa
should freeze pretty well, the bread definitely would, you could make 10 of moms zucchini casseroles and freeze them in aluminum pans, ready to bake, pull one out for dinner or keep them on hand when you have a sick or post surgical mommy-friend.
--The little sister
LOVE zucchini! I saw a crockpot recipe somewhere for eggplant parmigiana - do you think you could layer zukes, crumbs, cheese, spaghetti sauce,and get the same |
This inspiration of three local men collaborating with the creativity of area educators, 48,000 students in 53 schools are enjoying a fresh approach to Ability Awareness this academic year. Founders of Del Corazon (From-the-Heart), Don Routh, Josh Routh, and Bill Wheeler, support the curriculum with informative videos, personal presentations, and the loan for a week to each participating school of 10 wheelchairs. Children learn to appreciate their own abilities and embrace the challenge of enabling others to realize their full potential. Also known as the Wheelchair Foundation Schools Project, the initiative fosters respect for the strengths of peers coping with intellectual, developmental, and physical challenges, while raising funds to send wheelchair to hundres of individuals who would otherwise remain immobile.
The Wheelchair Foundation, established by Ken Behring in 2000, provides wheelchairs to people around the world who need but cannot afford a wheelchair. In many countries, a wheelchair costs a worker’s entire annual income. Todate, 955,000 wheelchairs have been delivered, bringing mobility, dignity, and hope to individuals aged two to over 102.
Since Bill Wheeler, founder of Blacktie Transportation, first invited Don and Josh to join him on a Wheelchair Foundation distribution trip, “the Three Amigos” have made 23 distribution trips to 14 Latin American countries, delivering 72,000 wheelchairs. Asked to identify his favorite trip, Josh insists: “All of them!” His father, Don, concurs. Each trip is different, every journey life changing.
Josh demonstrates to wheelchair recipients that their personal goals are achievable. Doctors predicted Josh, born with Cerebral Palsy, would be a quadriplegic incapable of speech. At 31, he spoke his first word: “Soup!” His indefatigable spirit continues to feed his father’s dedication. A graduate of San Ramon Valley High School, Josh relies on a wheelchair for mobility. Now 35, he lives independently, drives his own car to work, and has multiple sports accomplishments to his credit.
In Paraguay, From-the-Heart delivered a wheelchair to another Josh. Seeing his own son in the four-year old also coping with Cerebral Palsy, Don translated his parental experience into a message of hope for the mother. Recalling how grateful he would have been for the advice of a mentor, Don happily shares his experience, encouraging care givers to believe in the possibility that their charges will be, likeJosh, successful adults.
In spring 2012, Don Routh presented the concept of a schools program to Pleasanton Unified School District (PUSD) Superintendent Parvin Ahmadi. Ahmadi immediately recognized the value. “The potential of this endeavor as a true service learning project was incredible, and it was obvious that the impact to all involved would be profound,” she comments. “The project allows our students to learn and apply their knowledge while serving others globally. “Six PUSD elementary schools participated the following academic year. Six teachers joined a wheelchair distribution tour that summer and all came back as zealous advocates of the program.
Wheelchairs delivered to Costa Rica and Honduras this summer will carry the SRVUSD or PUSD logo, connecting donors and recipient.
The San Ramon Valley Unified School District (SRVUSD) recommended the project to all of its schools for 2013-2014, as did PUSD. Over the course of four months from late spring through summer, Don worked with Special Needs Parents and SRVUSD professionals to enhance the existing Ability Awareness curriculum to include lesson plans for all grades addressing physical, intellectual and developmental issues.
Terry Koehne, SRVUSD Communications Director, gladly accepted the task of promoting the program with district principals. “Don is amazing he provides every ounce of support a school needs, including background information, monthly newsletters, and updates, and makes himself available to do presentations for any group that needs it. “Support materials include a 17 page book list, movie suggestions featuring characters coping with disability, fun ways to try wheelchairs, and fundraising ideas. Proud that the fundraising aspect of the program will provide hundreds of wheelchairs to people who lack mobility, Koehne notes, “Providing students with real opportunities to experience the issue themselves gives more meaning to the fundraising component, and inspires them to get even more involved.”
Students and faculty members find Don Routh’s presentation riveting. He opens up by explaining “There are more than 100 million people with physical disabilities worldwide who are in need of a wheelchair. Thirty million of these are children and 90% of them do not to to school.” Lacking mobility, they have no access to education and often no social interaction with other children. Sometimes they have to crawl to reach basic items beyond their reach.
Montair Elementary School ran the project in October/November, embedding the program in all aspects of academics. Coin counting supported math, writing persuasive letters to the business community underscored language lessons, and walking into Danville to speak to local business leaders bolstered oral presentation skills. Dennis Simkin, Vice President, Manager recalls the day the students came to J.Rockcliff. “I was in awe of how professional and cute they were. “Simkin estimates that 30 or 40 people came out to hear their presentation.
Taking turns, students participated in a wheelchair basketball game. When one student finally managed to score, the crowd erupted in cheers. Elizabeth Campos spent part of a day teaching in a wheelchair and found maneuvering around her classroom a major challenge. Months later, in February, another school activity highlighted how much the project affected students. Campos wrote: “At Montair this week we are participating in a No-Name-Calling Week, and as Leadership was discussing ways to promote this, a few students brought up the fact that they actually think name-calling has decreased at school since Ability Awareness and the Wheelchair Foundation project because kids learned to accept others for who they are, no matter what they look like or their abilities.”
8 year-old Alejandro’s grandmother carried him to receive his first wheelchair, delivered by From-the Hart in March.
Gale Ranch Middle School ran the program in February. Counselor Lori Olson volunteered to coordinate. The opportunity for a field trip to the Blackhawk Automotive Museum was a huge incentive for students, and they returned from meeting Wheelchair Foundation President David Behring even morec ommitted to the cause. Blacktie provides field trip transportation and also stores and delivers the two sets of project wheelchairs.
Student reflections indicate how much Gale Ranch pupils learned spending time in a wheelchair. One student commented, “Before this I had never really thought about being in a wheelchair, not being able to do things normal people could, and feeling like you are separated from everyone.” Friends treated them differently. Another student said, “I now know that people in a wheelchair just wanted to be treated the same way as everyone else.”The value of mobility was clearly recognized. A third student said, “When the founder, Don, came to our school, he said not to feel sorry for the people who have wheelchairs but for the people who don’t have one.”
San Ramon Valley High Schoo land Monte Vista are holding Basketball Game Fundraisers showcasing their athletes competing against the nationally ranked BORP Warriors Wheelchair team. Local teams have volunteered to accept the challenge of playing in wheelchairs. CarlyLutz, SRVHS Leadership student reports that signupsfor “Ride-in-a-Wheelchair for a Day” are filling up quickly. Janet Willford, SRVHS Leadership teacher, describes planned lunchtime activities: “a wheelchair relay race, wheelchair bowling, and a pep rally.”
Costa Rica and Honduras (getting Foundation donations for the first time )are slated to each receive a container of 280 wheelchairs at a cost of $42,000 per container. As of April 17th, $61,258.05 has been collected, with many schools about to commence the project. Teachers, parents, and older students accompanied by an adult have been invited to come on this summer’s distributions trips. Ken Behring is awarding stipends of $2,000 toward travel costs to the elementary, middle, and high school achieving the highest per student donations.
Visit for information or to donate. |
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Fri 8th Mar at 8:00pm
A Night Of Illusion And Magic
@ Diamonds Showbar And Restaurant, Birmingham
Featuring: David Penn
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Venue: Diamonds Showbar And Restaurant
Address:
170-174 Great Hampton Row
Birmingham
B19 3JP 52.489323, -1.906512
Metro
→ St Pauls 6 min walk
Train
→ Jewellery Quarte 6 min walk |
Description
Add a rich look to your dining area with a set of eye-catching 19.75" W x 19.75" L x 31.50".
- Includes: One (1) Table;Six (6) Chairs
- Table Material: Faux Wood with Veneer
- Table Leg Material: Rubberwood
- Chair Material: Fabric
- Fabric Composition: 100% Polyester
- Chair Leg Material: Rubberwood
- Multiple Color Options
- Hand-Crafted Details
- Assembly Required
- Table Dimensions: 35.40 inches deep x 70.80 inches wide x 29.50 inches high
- Chair Dimensions: 19.75 inches deep x 19.75 inches wide x 31.00 inches high
- Seat Dimensions: 16.50 inches deep x 18.00 inches wide x 18.75 inches high
- Weight Capacity: 500 lb |
Austin Resource Recovery provides curbside recycling collection to single-family households and some small scale multifamily customers in Austin. With our curbside recycling program, you can mix recyclable paper, plastic, metal and glass in your blue recycling cart – no sorting required!
Use the My Schedule tool to get a personalized collection calendar for all residential curbside services, including recycling. You can add your schedule to Google, iCal or Outlook, or you can print it. You can also sign up for text, email or phone call reminders and alerts.
Place the following items in the blue recycling cart:
PAPER
BOXBOARD AND CARDBOARD
METALS
GLASS
HARD PLASTICS
Keep the following items out of the blue recycling cart:
Why We Can't Take These Items
The two local recycling processing facilities use automated systems to sort and bale the recyclables. Prohibited items will jam or damage automated machinery.
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Family Favorites: Make It Tonight!
From Time-Saving Suppers to a Restaurant Favorite, These Four Recipes Are Guaranteed to Get Raves
BEEF-AND-CHEESE RAVIOLI DINNER
Serves: 6
Hands-on time: 10 min.
Total time: 40 min.
1 lb. lean ground beef
1 small onion, diced
1 (8-oz.) package sliced fresh mushrooms
1 teaspoon vegetable oil
2 garlic cloves, minced
2 (26-oz.) jars tomato-basil pasta sauce
1 cup water
1 tablespoon dried Italian seasoning
½ teaspoon salt
¼ teaspoon pepper
1 (20-oz.) package refrigerated four-cheese ravioli
1 cup (4 oz.) shredded mozzarella cheese
Garnishes: Parmesan cheese, fresh basil leaves
1. Brown ground beef in a Dutch oven over medium-high heat, stirring 8 to 10 min. until it crumbles and is no longer pink; drain. Wipe Dutch oven clean.
2. Sauté onion and mushrooms in hot oil over medium-high heat 6 min. or until tender. Add garlic, and sauté 1 min. Stir in beef, pasta sauce, 1 cup water and next 3 ingredients.
3. Bring sauce to a boil; add ravioli. Reduce heat to medium-low, cover and simmer, stirring occasionally, 8 to 10 min. or until pasta is done. Stir in cheese. Garnish, if desired. Serve immediately.
PERFECT FOR SHARING
Served with a green salad this recipe will serve 6 generously so split half with a friend or neighbor. Or take it to the next potluck dinner right in the Dutch oven you cook it in.
Slow Cooker Recipe
BARBECUE PORK SANDWICHES
Serves: 8
Hands-on time: 5 min.
Total time: 8 hrs. and 5 min.
1 (3- to 4-lb.) Pork Roast (the cut often called Boston butt)
1 (18-oz.) bottle barbecue sauce
1 (12-oz.) can cola soft drink
1 (8-count) package sandwich buns
Potato Chips (optional)
Pickles (optional)
1. Place pork roast in a 6-qt. slow cooker; pour barbecue sauce and cola over roast.
2. Cover and cook on high 8 hrs. or until meat is tender and shreds easily.
3. Remove pork from barbecue sauce mixture. Shred pork and remove excess fat; add sauce to desired consistency. Spoon pork over sandwich buns. Serve with remaining sauce and chips and pickles if desired.
TO MAKE IT IN THE OVEN
Place roast in a lightly greased Dutch oven; stir together barbecue sauce and cola and pour over the roast. Before placing the lid on top of the Dutch oven, cover it with a double layer of aluminum foil. Bake, tightly covered, at 325° for 3 hrs. and 30 min. or until tender.
Heirloom Recipe
FAMILY FAVORITE TEA CAKES
Makes: 3 dozen
Hands-on time: 25 min
Total time: 2 hrs., 40 min.
1 cup butter, softened
2 cups sugar
3 large eggs
1 teaspoon vanilla extract
3½ cups all-purpose flour
1 teaspoon baking soda
½ teaspoon salt
2 tablespoons white decorating sugar crystals
1. Beat butter at medium speed with an electric mixer until creamy; gradually add sugar, beating well. Add eggs, 1 at a time, beating until blended after each addition. Add vanilla extract, beating until blended.
2. Combine flour, soda, and salt; gradually add flour mixture to butter mixture, beating at low speed until blended after each addition.
3. Divide dough in half; wrap each portion in plastic wrap, and chill 1 hr.
4. Preheat oven to 350°. Roll half of dough to ¼-inch thickness on a floured surface. Cut out cookies with a 2½-inch round cutter, and place 1 inch apart on parchment paper-lined baking sheets. Sprinkle cookies with decorating sugar crystals.
5. Bake 10 min. or until edges begin to brown; let stand on baking sheet 5 min. Remove to wire racks to cool. Repeat procedure with remaining dough.
RESTAURANT RECIPE
Cracker Barrel Hashbrown Casserole
This signature side dish is a menu favorite at the restaurant's 577 locations.
Serves: 8-10
Hands-on time: 10 min.
Total time: 40 min.
1 (10¾-oz.) can cream of chicken soup
1 (8-oz.) block colby cheese, shredded
½ cup onion, chopped
½ cup margarine, melted
½ teaspoon black pepper
½ teaspoon salt
2 (30-oz.) packages frozen country-style hash brown potatoes
1 cup shredded colby cheese (optional)
1. Preheat oven to 375°. Combine first 6 ingredients stirring until well blended.
2. Add 10½ cups frozen shredded potatoes to bowl. Spoon mixture into 2 lightly greased 1½-quart baking dishes or 1 (9- x 13-inch) baking dish. Sprinkle with 1 cup colby cheese, if desired. Bake 25 to 30 min. or until golden brown. Serve immediately.
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Project-Based Learning
2 DAY WORKSHOP
Full Registration
$660.00 (inc GST)
Cost includes program materials, morning tea, and lunch.
PROGRAM DETAILS
2 DAY WORKSHOP
This two day program is highly suitable for School leaders, heads of department, team leaders and teachers
Project–Based Learning (PBL) is one powerful key to unlocking student engagement. This 2-day course is designed as a practical introduction to PBL. It will provide atendees with the key elements for doing PBL. Through the course some of the strategies for implementing successful projects in a school will be discussed and explored.
The program is designed to cover:
Deep understanding of PBL
Development of effective and powerful projects
Understanding of key ingredients of PBL
Understanding of different approaches
Enabling Leadership of other staff to PBL implementation
ABOUT THE PRESENTERS
David Price OBE is an expert in learning for a complex future, David writes, talks, trains and advises around the world, on some of the biggest challenges facing business, education and society. He has led innovative educational projects that have transformed practice in many countries. In 2009, he was awarded the OBE for services to education, by Her Majesty the Queen.
Clare Price is an Education Consultant with over 20 years experience of working as a lecturer, a strategic manager within school improvement and as a producer and trainer for schools and the cultural sector.
She is a highly experienced trainer and facilitator and has led extensive programmes of professional development for school leaders, teachers and artists. Clare manages a portfolio of development work for school networks and cultural organisations in the UK, including project design and management, research and evaluation, consultancy, creating teaching resources and producing numerous large-scale conferences and events.
Over the last 7 years she has increasingly worked internationally, delivering a range of training for schools in 4 continents – programmes include Project-Based Learning, Deeper Learning, Improvement by Design and Drawing for Learning as well as bespoke workshops for events and conferences. |
Description
Gorgeous minimalist Wish-lets dinosaur wish bracelet. Worn by itself or as part of a stack, it looks great either on the wrist or ankle. Treat yourself, or a friend or loved one today. Wear this charm and remember these life lessons from a dinosaur.
Made using 1mm waxed cotton cord, with a silver-tone dinosaur.
This item is not a toy and not suitable for young children.
Catching Dreams Crafts 2021. All rights reserved. Wish-lets is a registered trademark.
1,559 total views, 1 views today |
When I lived in New York City, we seldom went into the park. It was dangerous at night and during the day we had other things to do. I did go to a free play one summer at the Delacorte, but that was about it. However, recently we were visiting for some theater R&R and took a morning’s stroll.
The “duck traffic” was fun.
People always talk about the fall colors in New England but the leaves turn in NY as well. I want to note that although the fuchsia tree is quite striking, I didn’t push the colors in these pictures. They are WISIWIG (what you see is what you get – a real IT term…)
It was a glorious day; lots of pedicabs. Expensive pedicabs – the signs said “3.75 per minute per ride.”
We passed a couple of benches that had little plaques – probably the benches were financed by the plaque owners. You can guess the quote applicable to my life…hint: my husband’s nickname isn’t Grubby!
I couldn’t resist a couple of shots of buildings. The art deco decorations were on a 6 or 8 story building, between each floor. Above almost every one, in the window, was an air conditioner. The owls were on another window. There are so many beautiful old buildings in the city and it appeared that many had been newly cleaned. There was also a bunch of construction midtown, new replacing the old. The city has changed a lot since I lived there, perhaps for the better…
Beautiful pictures Terri.
Looks like a wonderful way to spend an autumn day. Beautiful!
I love the art deco terracotta!
Beautiful pictures Terri… How I do miss the autumn … sigh… |
Two foot and counting. Had the 2n out yesterday along with the dearborn V plow. Made passes about 11 am and about 4:30 pm. Was up to my knee when I came in. It's supposed to by out of here by noon then will be digging out.
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UK Progressive Rock act Drifting Sun have announced that they are in the final stages of completing their forthcoming new concept album ‘Twilight’ and it is now available as a pre-order ahead of a 1st September release at the band’s official website here:
To celebrate the release of the album Drifting Sun are offering a ‘name your price’ download of the track Soldiers from their bandcamp site here:
‘Name Your Price’ download of Soldiers
As a ‘thank you’ for pre-ordering ‘Twilight’, the band are giving away the new single Eternal Cycle with each pre-order. Once you have ordered from the website, you will receive a free download code direct to your email address..
Pat, Manu, Peter Falconer (vocals), Dan Storey (guitars) and Will Jones (drums) recorded the previous album ‘Safe Asylum’ that was released on the 21st May 2016. This was the last record to feature Dan on guitars and his replacement, Mathieu Spaeter (of The Franck Carducci band) was recruited in time to record the new album ‘Twilight’. |
Low-fat Double Chocolate Brownies
Low-fat Double Chocolate Brownies recipe
Ingredients
Directions
Preheat oven to 350°F.
Spray a 9-by-13-inch baking pan with cooking spray or grease with butter.
Melt chocolate and butter in a double boiler over barely simmering water. (Alternatively, place in a small microwave-safe bowl and microwave on Medium, stirring every 30 seconds, until melted and smooth.)
Add flour, cocoa and salt in a medium bowl, and whisk until well blended.
Beat egg whites, eggs and brown sugar in a large mixing bowl with an electric mixer.
Add applesauce, oil and vanilla, beat until well mixed.
Add the chocolate-butter mixture, beat until well mixed.
Add the flour mixture and mix just until incorporated.
Stir in chocolate chips.
Transfer the batter into the prepared pan, spreading evenly.
Sprinkle with walnuts or pecans if desired.
Bake until the top springs back when touched lightly, 22 to 25 minutes.
Transfer to a wire rack and allow to cool completely.
Dust with icing sugar if needed.
Cut into bars. |
Humanities › History & Culture Plebeian Tribune Share Flipboard Email Print Hulton 10, 2018 The Plebeian Tribune—or tribuni plebis 5. By 457 B.C., there were 10. The Plebeians Secede. Source A Companion to Latin Studies, by J.E. Sandys |
When it comes to remodeling your home, or performing any interior demolition project, many homeowners ask, “When is the best time to do it?”
The bottom line is: The best time is whenever you’re ready to do it!
However, certain times of year are better than others in terms of cost-efficiency and ease of planning.
Fall and winter months are a great time to tackle interior demolition projects for a number of reasons.
First and foremost, the colder months tend to be less busy for contractors, which means you’re more likely to get a better deal on services and materials.
Another reason contractors appreciate colder months and are more inclined to give you a lower price? Working inside during the fall and winter is much more bearable than working inside during spring and summer.
This is another reason why some people like to hold off on interior demolition projects until the weather cools down.
If you tend to travel during the holidays, check an interior demolition project off your list this winter.
The contractor(s) can complete some, if not all, of your project while you're away, so you don't have to deal with the mess that comes with many interior demolition projects.
Also, if your project is non-invasive, or you are willing to have a demolition/renovation crew in and out of your house around the holiday season, the cooler months are a great time to schedule interior projects of all shapes and sizes.
Find an interior demolition contractor near you
Learn more about interior demolition: |
MONDAY, June 20 — More good news for LeBron James fans: You can celebrate last night’s NBA championship with a pizza from Blaze Fast Fire’d Pizza, of which the basketball star is part owner.
“Our mission at Blaze is really simple — we’re taking pizza back to its roots,“ said Jim Mizes, president and COO of Blaze Pizza. “By making dough in-house, carefully sourcing ingredients and cooking by fire, we’re giving guests a great way to enjoy artisanal pizza without the wait.”
To celebrate the grand opening of its Frandor location, the restaurant will offer free build-your-own pizzas to anyone who follows Blaze Pizza on Facebook, Twitter or Instagram. The offer is valid tomorrow from 11 a.m. to 9 p.m. The record for free Blaze pizzas given out in one day is 2,100, and the company is hoping to surpass that with tomorrow’s promotion.
The quickly growing chain opened its first location in Irvine, Calif., in 2012, offering its thin-crust, custom-made pizzas, as well as signature items like blood orange lemonade and s'mores pies. The restaurant features an interactive, open kitchen that allows guests to customize their pizza with a variety of fresh ingredients mostly free of artificial flavors, colors, preservatives and fillers and then watch them cook in the open-flame ovens.
The company operates 141 restaurants in the U.S. and Canada. The new Lansing-area location is 3,300 square feet and seats 61 people indoors with an additional 58 seats on its patio. With Blaze Pizza also offers a restaurant fundraiser program and plans to partner up with local schools, sports clubs and other organizations to host fundraising events.
Blaze Pizza
10:30 a.m.-11 p.m. Sunday-Thursday; 10:30 a.m.-midnight Friday-Saturday
300 N. Clippert St., Lansing
(517) 580-7697, blazepizza.com |
Linda Fong
Canyon, 2001
acrylic on wood, 16 x 19 inches
Linda Fong
Veiled Mountain, 2001,
acrylic on wood, 16 x 19 inches
Journey: Recent Paintings By Linda Fong
June 5 - October 14, 2001
Honolulu artist Linda Fong’s new series of paintings had its beginnings in an earlier series of large paintings which the artist left unfinished. Fong cut up color snapshots of the abandoned works into small rectangles and used these fragments as inspirations for new compositions. She was interested in how the cropped forms in the fragments suggested landscapes. Fong’s new paintings, painted in acrylics on cotton muslin mounted on wood panels, are all identical in size and horizontal in format (chosen, Fong says, because it is a classic landscape shape). Displayed around a gallery the works appear like still images from a film, taking the viewer on a tour through a range of spaces and terrains – hence the exhibition title, "Journey".
Fong refers to her works as abstract landscapes, "not based on any actual places, more places in my mind." Fong’s shapes and colors evoke sky, hills, valleys, water, vegetation, helping viewers orient themselves in the composition. Yet at the same time, Fong makes use of multiple perspectives and interplay of foreground and background to create a spatial ambiguity. "The feeling I want to convey to the viewer," she says "is one of not knowing exactly where you are." With their contrast of bright and dark colors, light that seems to emanate from within, and sinuous, swirling lines floating through the compositions activating space and making tangible a sense of atmosphere, Fong’s paintings are, as she has described them, "ethereal places of mystery." |
Christina Xiong
HAULING THROUGH MOUNTAINS
We don’t know it yet but it will take
four more hours, five more than usual,
to reach my dad’s new house in Orchard
Park. I will learn the term “house poor”
seeing their two story Colonial, barren
of furniture, with dad’s rusted black
Monte Carlo parked in the driveway.
We stop hourly so he can pour
water in the bubbling radiator to quell
its tantrum, cool its boiling. Our new stepmother
stands on the side of the road, silhouette
of Farrah Fawcett hair, feathered and golden.
I wonder where our new stepsister
is during this trip, imagine her with my
grandpa watching hockey, eating butterscotch
disks grandma keeps in crystal bowls.
My stomach growls. I pull a Snickers bar
from my stash, break off half for my older sister.
I can’t sleep. We are hauling
a trailer behind us, through Pennsylvania
mountains, June, but we see our breath
like clouds of marijuana smoke pouring
from the front seat, or the radiator’s steam.
The trailer holds a Chevrolet corpse.
My dad, a mad scientist, will resurrect
this El Camino, like Frankenstein.
Hefty bags with red drawstrings,
hold hand me down clothes that don’t fit,
crowd the backseat, provide cushion.
Somewhere in the mountains, I tear
a hole in one of the black plastic bags,
weed out a handful of too-small
turtlenecks, wrap myself up.
My sister rolls her eyes,
shakes her cloak of chocolate curls,
she fishes in the bag and finds
a maroon wool sweater, moth-eaten,
to wriggle her narrow shoulders into.
We loll against garbage bags, like bums,
eyes avoiding holes in the floorboard
blurred road sandpapering past beneath
holey carpet. I try cracking a joke
about the Flintstones, but it falls flat.
The car radio scratches out “Maggie,”
Rod Stewart, mountain reception rasping.
Another stop on the road’s shoulder.
Dad mutters “God damn it.”
Tractor trailers careen past hairy curves
harrumph, umph umph of Jake brakes.
I imagine my dad splattered on the side of the road,
heat blasting in the state trooper’s car.
He’d stop for burgers and fries, salty consolation,
shake his big trooper’s hat back and forth with a “tsk.”
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Acetaminophen
Acetaminophen is used to treat pain and reduce fever. Acetaminophen comes in many combination products. Read all medication labels carefully to make sure you do not take too much acetaminophen.
Acetaminophen Overview
Acetaminophen is both an over-the-counter and a prescription medication. Both forms of the medication are used to treat mild to moderate pain and to reduce fever. This medication page refers to the prescription form of acetaminophen.
Acetaminophen belongs to a group of drugs called analgesics and antipyretics. These work by changing the way the body feels pain and by cooling the body.
The prescription form of this medication is available in an injectable form to be given directly into a vein (IV) by a healthcare professional.
Common side effects of acetaminophen include nausea, vomiting, headache, and insomnia.
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Acetaminophen Cautionary Labels
Uses of Acetaminophen
Acetaminophen is a prescription medication used to treat mild to moderate pain and reduce fever.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Acetaminophen Brand Names
Acetaminophen Drug Class
Side Effects of Acetaminophen
Serious side effects have been reported with acetaminophen. See the “Acetaminophen Precautions” section.
Common side effects of acetaminophen include nausea, vomiting, headache, and insomnia in adults and nausea, vomiting, constipation, itching, and agitation in children.
This is not a complete list.
Acetaminophen Interactions
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven)
- isoniazid (INH)
- certain medications for seizures including carbamazepine (Tegretol), phenobarbital, and phenytoin (Dilantin)
- medications for pain, fever, coughs, and colds
- medications for mental illness and nausea such as chlorpromazine, thioridazine, perphenazine, and prochlorperazine (Compro, Procomp)
This is not a complete list of acetaminophen drug interactions. Ask your doctor or pharmacist for more information.
Acetaminophen Precautions
Serious side effects have been reported with acetaminophen including the following:
- Liver injury. Acetaminophen should be used cautiously in patients with liver impairment or disease, alcoholism, malnutrition, dehydration or severe blood loss, or severe kidney injury. Tell your healthcare provider right away if you have some or all of the following symptoms of liver injury.
- vomiting
- nausea
- fatigue
- abdominal pain
- Serious skin reactions. Tell your healthcare provider right away if you have red, peeling, or blistering skin.
- Allergy and hypersensitivity reaction. Tell your healthcare provider right away if you have some or all of the following symptoms of an allergic-type reaction:
- hives
- itching
- swelling of the face, throat, tongue, eyes, hands, feet, ankles, or lower legs
- hoarseness
- difficulty breathing or swallowing
Do not take acetaminophen if you:
- are allergic to acetaminophen or to any of its ingredients
- have severe liver impairment or active liver disease
Acetaminophen Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of acetaminophen, there are no specific foods that you must exclude from your diet when receiving this medication.
Inform MD
Before taking acetaminophen, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to acetaminophen or to any of its ingredients
- have liver problems
- have kidney problems
- drink alcoholic beverages
- are pregnant or breastfeeding
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.aminophen falls into category C. There are no well-controlled studies that have been done in pregnant women. Acetaminophen should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.
Acetaminophen and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
Acetaminophen has been detected in human breast milk after oral administration. No studies have been conducted with intravenous acetaminophen Because of the possibility for adverse reactions in nursing infants from acetaminophen, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.
Acetaminophen Usage
Take acetaminophen acetaminophen at the same time. adult dose of acetaminophen for the treatment of pain and/or fever reduction is 1000 mg every 6 hours or 650 mg every 4 hours. The maximum daily dose for adults for all forms of acetaminophen is 4000 mg.
The recommended dose of acetaminophen for children for the treatment of pain and/or fever reduction is 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours. The maximum daily dose for children for all forms of acetaminophen is 75 mg/kg.
Acetaminophen Overdose
If you take too much acetaminophen, call your healthcare provider or local Poison Control Center or seek emergency medical attention right away.
If acetaminophen is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
Other Requirements
- Store acetaminophen at room temperature.
- Keep this and all medicines out of the reach of children.
Acetaminophen FDA Warning.
|
DIY Food
Eat Pizza Pockets, Relive the 90s
Popular on Food52
2 Comments
Hillary R. July 29, 2015
OOh this looks great! I recently made pizza donuts, which were a hit. () Definitely going to try these. Also, love that Backstreet Boys are almost part of the recipe.
AntoniaJames July 28, 2015
Not sure the relationship between stromboli and what you show here -- perhaps the slightly different format and greater filling to crust ratio makes them first cousins, not sisters -- in any event, here's my muffaletta-inspired take: ;o) P.S. I've never had a commercial pizza pocket so I don't know how these compare.
Join the Conversation
See what other Food52 readers are saying. |
NARROW
Use of multiple oxygen isotope proxies for elucidating Arctic Cretaceous palaeo-hydrology
Abstract Stable oxygen isotope analysis of siderite and dinosaur tooth enamel phosphate from the Campanian–Maastrichtian Prince Creek Formation, Alaska, USA, are analysed to determine the palaeohydrology of the ancient Colville Basin north of the Ancestral Brooks Range. δ 18 O of freshwater siderites relative to V-PDB ranges between −14.86 and −16.21‰. Dinosaur tooth enamel δ 18 O from three different sites (Kikak–Tegoseak, Pediomys Point, Liscomb) range between +3.9‰ and +10.2.0‰. δ 18 O meteoric water are calculated from δ 18 O siderite that formed at seasonal temperatures ranging from −2 to 14.5 °C, with a mean annual temperature of 6.3 °C. At 6.3 °C, the δ 18 O w calculated from siderite ranged between −22.23 and −20.89‰ V-SMOW. Ingested water compositions are estimated from dinosaur teeth assuming body temperatures of 37 °C and local relative humidity of 77.5%, resulting in values ranging from −28.7 to −20.4‰ V-SMOW, suggesting consumption of meteoric water and orographically depleted runoff from the Brooks Range. The ranges in calculated δ 18 O meteoric water are compatible between the two proxies, and are mutually corroborating evidence of extremely 18 O-depleted precipitation at high latitudes during the Late Cretaceous relative to those generated using general circulation models. This depletion is proposed to result from increased rainout effects from an intensified hydrological cycle, which probably played a role in sustaining polar warmth. Supplementary material: Parameters used for generation of equations compared to Kohn (1996) can be found at |
The mini-grants opportunity has been put on hold until further notice
Mini-Grants
Priority will be given to proposals that evaluate evidence-based learning through performance outcomes. These include pre- and post-test, portfolio evaluation and longitudinal tracking of student achievement. Proposals should describe in detail how the award will potentially improve instruction in a course or curriculum and how that improvement will be demonstrated. Successful proposals will also provide clear evidence of instructional practices that encourage active learning. We recommend that proposals be approximately two to three pages (about 500-750 words), with about two pages of narrative and one page for the budget. The best proposals will explain anticipated improvement in teaching, its efficacy in terms of current scholarship on learning, and appropriate plans for assessment. The budget should include specific information about proposed expenditures. Any citations should be in an established scholarly format.
Mini-grant awards will not exceed $5,000. Review of submissions will begin on March 30 for fall semester awards and Oct. 1 for spring semester awards. Early submission will improve chances of funding.
For additional information or questions about the application process, please contact the center at [email protected].
Past Mini-Grant Faculty Projects
- "Teaching Silk Road History with Google Earth," by Ruth Mostern (Spring 2012)
- "PATHOGEN Project and Related Software/Hardward" by Maria ALbert, Kristina Krona, and Miriam Barlow (Fall 2012)
- "CORE 1 The World at Home" by Liz Olson (Summer 2011)
- "Sociology Survey Project" by Irenee Beattie (Spring 2011)
- "WRI 1 Library Instruction" by Susan Mikkelsen, Sara Davidson, and Teal Smith (Spring 2009)
- "Goals-Oriented and Outcome-Based Syllabus Design" by Virginia Adan-Lifante (Summer 2008)
- "Developing SYllabus and Learning Strategies for Evolution (BIS 141)" by Mike Dawson (Spring 2008)
- "Skeletal Evidence for Human Evolution: Hands-On Exercises with More clearly Stated Objectives and Peer Based Follow Up" by Vicki Wedel (Spring 2008)
- "Curriculum Revision of ECON 100" by Katie Winder and Justin Hicks (Spring 2008) |
Using a PageMethod to Look Up City and State based on Zip Code
By: Brian Dobberteen
This one seems like a pretty good one to try and start with – the simple lookup of a city and state based on a zip code entered on a form. We’ll be using Yahoo’s map API here, for which you’ll need to grab an Application ID (freely available at).
Be sure to save that in a suitable location, as we’ll need it to form our request to the API later via a simple HTTP GET request to Yahoo’s server. This GET request is about as simple as they come, only needing the Application ID and the zip code in question as query string parameters. In fact, you can build this request and paste it into your browser’s address bar to verify that you have it right. It looks like:
If you try navigating to the above URL, replacing <YOUR APP ID> with the Application ID you received from Yahoo and <ZIP CODE> with the zip you’d like to check out, you should receive an XML response that looks similar to this:
So, getting the info is simple enough, and there are countless ways to handle this, to be sure. In fact, using something like jQuery or even the Microsoft AJAX Library would be very simple and not necessitate the need for PageMethods and the like. So maybe this is a somewhat contrived use of PageMethods, but let’s do it anyway!
I must add, after giving it some more thought, it seems that moving this entire operation to the client would expose our Yahoo Maps Application ID, which is probably not an ideal situation. jQuery would certainly have no problem accomplishing our task, easily handling the parsing of the XML response and so on.
At any rate…
Go ahead and create a new ASP.NET web page and name it whatever you’d like. I’ll be using Default.aspx here, but it really isn’t important. Following the creation of the new page, we’ll be presented with the familiar blank ASP.NET page, replete with a form tag and one lonely div. I’m sure you’ve all seen it a million times, but this is what we’ll be starting with:
As you can see, we’ll be using the code-behind model rather than including the script in the .aspx file seen above. In order to access the PageMethod that we will soon be creating, we need to add a ScriptManager object to the page in order to generate the javascript proxy to our server-side method. This couldn’t be much easier, simply add:
Obviously, the EnablePageMethods attribute is key here, and the only change needed to the default ScriptManager.
Now, let’s add a quick textbox to the form:
And right underneath the asp:TextBox, let’s add an asp:Label element:
Note that we added the attribute ‘onchange’ to the TextBox – it’s set to a function that fires any time the contents of the TextBox change. The function that responds to the event:
Not a whole lot to that, clearly. However, thanks to the ScriptManager we placed on the page, the plumbing between our server-side PageMethod and our client-side javascript has been taken care of. And in this case, we are only passing one parameter to our PageMethod, whose signature is seen here:
Note the Imports System.Web.Services – this is the namespace where the WebMethod() attribute lives. As you can see, this method, which is in our code behind file (Default.aspx.vb) takes the string parameter ‘zip’ and returns a simple CityState object:
This little class is defined on the same page as our code behind file and will automatically be serialized in order for our client-side code to consume it.
The second parameter in PageMethods.GetCityStateFromZip(zip, onGetCityStateComplete) is the name of a callback function that will execute upon completion of our call to the PageMethod.
The result parameter being passed here is a CityState object, as defined in the PageMethod’s signature. It has been nicely serialized into a javascript object with properties that are easily accessed. We use the Microsoft AJAX $get() function to find the label we created earlier and then set its innerHTML to the name of the City, a comma, and the name of the state (i.e. Santa Cruz, CA).
Lastly, let’s check out what’s going on in our PageMethod in terms of actually fetching the data from the Yahoo Maps API
Hopefully the code is somewhat self-explanatory, but let’s review it. .NET is kind enough to allow us to create a new XmlReader object by calling the static method <b<XmlReader.Create() and passing it a URL (line 6). Since we already know how to build the proper URL to get our XML response from Yahoo Maps, we just pass this value. We’re getting the zip code from the zip code text box following its onchange event. In the call to XmlReader.Create() I’ve used two constants, one for the base URL to the Yahoo Maps API and the second for my Application ID. Obviously you’d need to set the Application ID to reflect the one you received earlier.
Presumably, the request went through without a hitch and you are now in possession of a successful XML response. I know, I know, there is absolutely no validation going on here or effort to do any sort of error checking. It’d probably wouldn’t hurt to make sure that the zip code was in a usable format, that the XML response was actually valid, etc. Maybe we can touch on that in a future article.
So, anyways, we now have an XmlReader object and we are going to read it line-by-line in a While loop (line 7), during which a couple of If statements look to see if we’ve come across the city and state elements in the response. I also check to make sure that our XmlReader is at an XML start element (i.e. <City> vs. </City>) so that everything goes smoothly. I don’t know if this is the best way of going about this, but it works, so I didn’t complain 😉
We created our CityState object at the beginning of the function and end up setting its two properties during the read of the XML response. Assuming all went well, the client javascript is returned a CityState object with the names we’re after. And, as we discussed earlier, we simply take that data and slightly reformat it and then add it to our page, which is what we set out to do!
July 10th, 2009 at 9:54 am
[…]). […]
July 14th, 2010 at 2:43 am
Great tutorial. Though it did not work for me in VS2008 and C#.
Error with page methods. But still seemed a good tutorial
Thanks |
Best Buy ad: Our people are better than Wal-Mart's
A new TV spot for Best Buy features a sales associate who describes how a customer called her from Wal-Mart and how she solved his problem.
Now that Circuit City has enjoyed something of a last lap in physical retail, Best Buy seems to have decided to take on another large rifle in electronics retailing: Wal-Mart Stores.
Wal-Mart has been upgrading its electronics offering and Best Buy clearly sees the Arkansas retailer as a potential source of pain and anguish.
In Best Buy's new TV ad, we meet employee Rachel Muñoz from Best Buy store (No. 1,473, if you're interested) in McAllen, Texas.
Muñoz, who seems like a very nice woman, tells the story of how she took a call from a man who asked some searching questions about TVs. It transpires the man was not merely full of purchaser's angst, but also at Wal-Mart.
Muñoz recalls saying to him: "Well, you're obviously calling us because we're knowledgeable."
So she persuaded him to hotfoot it to store No. 1,473, where he became, Muñoz thinks, "a BestBuyer for life."
I must confess I did stop a little when I heard Muñoz's claim to knowledge. I read CNET's Sharon Vaknin's slightly sobering description of her experiences as a Best Buy employee. Example: "We have no formal training in consumer electronics."
But one's view of a retailer is always colored by one's own experience--very often the first experience--with the retailer's service.
I confess that at my local Best Buy (I'm sorry, I don't know the number of the store. Until today, I didn't know they had numbers like schools in Eastern Europe) it is very easy to get a "Hello, welcome to Best Buy" and a little more difficult to attract an associate's attention thereafter.
And once, when I inquired about buying a rather substantial sound system and TV, I was told I would have to wait 10 days for the Geek Squad to drive the two miles to my house to install it. Which the associates found terribly normal and I found terribly disappointing. (I bought elsewhere.)
Still, it is heartening to think a retailer might actually put itself in the position of using its customer service as a point of difference.
The only problem will be, naturally, delivering the service. |
TriMet is continuing its tradition of free fares to encourage revelers to make safe choices on the country's big night out. After 8:00 p.m. on NYE, TriMet's MAX and bus trips will be free throughout the TriMet service area.
Buses and trains will run on regular Saturday schedules and MAX will add an extended late night schedule. Here are more details from TriMet's web site:
MAX Blue, Green and Yellow lines
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Great vegan gluten free fast food options. Salads are great, gf beet burger is so good! Highly recommended this is feel good food with no guilt because it's healthy.
617 9th Ave, New York, NY 10036
Amazing food! Great gluten free options!
617 9th Ave, New York, NY 10036
I was skeptical bit the food is delicious
Be the first to add a photo! |
News Releases by Email
News Release
Friday, August 13, 2010
Media contact: Joy Hill, 352-258-3426
Photo Gallery
Jarhead.
The FWC. Unfortunately, the good mother bear
refused to be tricked by the baited trap.
After eight days of sightings, two days went by
when nobody saw the bear family...
To date, the FWC has not gotten any further reports
of the bear family. And that's good news indeed. |
Module 7500
Applied Choice Analysis
Instructors
Prof. Dr. Jutta Roosen, Marketing and Consumer Research, Technical University of Munich
Dr. Matthias Staudigel
In addition, guest lectures will contribute to specific topics of the course.
Module Description
The course will introduce choice modelling techniques for consumer and marketing analysis. After starting with the theory of consumer choice, the course will discuss different types of choice data available. The main part of the course will focus on choice experiments. It discuss the specifics of choice experiments, possible experimental designs and data collection procedures. Participants will be familiarized with data handling and analysis considering conditional logit, random parameters logit and latent class analysis. To obtain an overview of the literature, participants will present papers from their respective field.
Course Outline
- Introduction
- Decision data and choice models
- Setting up stated choice experiments: Experimental design, alternatives, attributes and levels
- Exercise: Handling choice data, Brand choice
- Conditional logit model
- Random parameters logit model
- Latent class model
- Information search and choice behavior
Teaching methods
Lectures (40%), seminars (20%), PC-demonstrations (20%), hands-on-exercises (20%)
Grading
Presentation (40%), assignments (40%), participation (20%)
Credit points: 3
Requirements
Consumer Behavior, Econometrics, Microeconomics, Basic Stata Skills.
Software: Stata.
Language: English.
Organization and time
Students will receive a paper assignment two weeks prior to the course. These papers are presented throughout the week. In addition about 40% of the course is done in the computer lab using the software Stata. The course is planned for Mo 13:30-16, Tu-Th 9-12 and 13:30-16, Fr 9-12 and will take place in Freising-Weihenstephan. For further information please contact Helga Brandstetter ([email protected], 08161 / 71 3316).
References
- Bettman, J. R., Luce, M. F., Payne, J. W. (1998). Constructive Consumer Choice Processes. Journal of Consumer Research, 25(3), 187-217.
Chintagunta, P. K., Nair, H. S. (2011). Discrete-Choice Models of Consumer Demand in Marketing. Marketing Science, 30(6), 977-996. doi: 10.1287/mksc.1110.0674
- Hensher, D. A. (2006). How Do Respondents Process Stated Choice Experiments? Attribute Consideration under Varying Information Load. Journal of Applied Econometrics, 21(6), 861-878. doi: 10.1002/jae.877
- Hensher, D. A., Rose, J. M., Greene, W. H. (2005). Applied choice analysis: A primer. Cambridge: Cambridge University Press.
- Louviere, J., Hensher, D., & J. Swait (2000). Stated Choice Methods. Cambridge: Cambridge University Press.
- Reutskaja, E., Nagel, R., Camerer, C. F., Rangel, A. (2011). Search Dynamics in Consumer Choice under Time Pressure: An Eye-Tracking Study. American Economic Review, 101(2), 900-926. doi: 10.1257/aer.101.2.900
- Scarpa, R., Thiene, M., Hensher, D. A. (2010). Monitoring Choice Task Attribute Attendance in Nonmarket Valuation of Multiple Park Management Services: Does It Matter? Land Economics, 86(4), 817-839.
- Swait, J., Louviere, J. (1993). The role of the scale parameter in the estimation and comparison of multinomial logit models. Journal of Marketing Research, XXX(August), 305-314. |
Face masks FFP2 Black - 95% filtration - CE0161
Face masks FFP2 Black self-filtering mask with 5 high-efficiency layers available in batches from 10 to 300 units. They retain at least 95% of incoming and outgoing contaminants and bioaerosols. The black FFP2 masks Galmask are manufactured in Spain and have European approval. These approved Black FFP2 masks are especially recommended for professionals, vulnerable groups or people who want to obtain the highest protection in spaces with little ventilation or very crowded with people. Galmask FFP2 type masks significantly reduce the risk of exposure to solid and liquid environmental aerosols or close contact with possible asymptomatic or positive people for biologically transmitted diseases. Graphene free product. Includes a clip for head attachment. CE 0161 notified body.
Face masks FFP2 Black Galmask made in Spain - Characteristics
- Made in Spain
- Color: FFP2 Black
- Lots from 10 units to 300 Black black.
FFP2 Black Mask - How to apply
1. Place the nose piece on top making sure the identification etching on the mask is facing out
2. Stretch the adjustable side bands and place them behind the ears
3. Correctly fit the nose piece over it
4. Correctly adjust the nose piece on it and rest the ends of the black ffp2 mask against the cheeks to obtain a good seal
5. Check after the adjustment by placing your hands on the mask that when exhaling air, it does not come out through the sides of the mask or rise towards the eyes
Return to ➝ Face Masks FFP2-FFP3 |
Empanada Nation
Location
Campos Rueda Bldg., Urban Ave., Makati, Metro Manila
Stats
- 7 Reviews
- 0 Recommend
- 7 Reviewers
Primary Details
- Category:
- Snack
- Business Hours
- Reopens Thu: 9:00a - 11:00p<<
Do NOT order Dinakdakan! Unless you love taba and pure taba. I asked their staff why my meal doesn't have any meat, pure fat. And she answers that it's because it is made of pig's cheeks. Sabi ko eh bakit, "grilled pork" ung description sa menu nyo? Inulit lang nya sagot nya that it is made of pig's cheeks. I understand that this is some Ilocano menu and maybe I am not fully aware of what I ordered but I tried Dinakdakan before and it has something I can eat not purely fat. Well if there's anyone here who is Ilocano and can explain the dish, please do. I'll greatly appreciate it. I didn't finish my lunch that time kasi puro TABA talaga bumili nalang ako ng kamote cue sa labas.
Bought my ilocos empanada here so many times! This is the only authentic ilocos empanada i've ever tasted within NCR! Or maybe the most delicious one for me. Ü the branch im actually reviewing is the one near makati medical center but it's not showing here in looloo.
Their bagnet is also satisfying!
The staffs are not really friendly or accommodating but i'd still give 5 stars since i love the food so much and the staffs may not be pleasing but they havent annoyed me so far. Ü love this place!
I loved it.
Bumped into a place while in Makati and since i was craving for a ilocos empanada i decided to give it a shot. The empanada is filling good taste the traditional empanada that I come to love while I was in Ilocos. I ordered the double longganisa which cost 92 pesos and it's a value for my money. The empanada is oily obviously because it's fried but the juicieness of the empanada is amazing. The question will I come back? A resounding yes and will try other selections.
it took a while before my number was called to be picked up at the coubter to thin there were only 3 tables occupied including ours. dbt go here if your hungry
Service is slow. The bagnet is too dry. Nothing special with their Special empanada.
this recently opened snack place offers a variety of food originated in Ilocos from bagnet to Ilocos Empanada. They do have a variety of Empanada from regular to "double double". Though Im not really sure what the difference is. Their Empanada's are ok but for those who are health and figure conscious, you may wanna skip empanada coz theyre too oily. you may opt to order Empanachos instead.
The place is nice but their service is quite slow. |
Devry University Loop Campus
225 W Washington StCategories: Education, Universities
Chicago, IL 60606
Phone: (312) 372-4900
Website:
Chicago, IL 60606
Phone: (312) 372-4900
Website:
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About This Business
Services Offered: Admissions, Career Planning, Financial Aid, Registration, Scholarships
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Second to skincare, the next biggest obsession in my life has to be wax melts. I own 5 warmers, I am always wanting more too. I love that feeling you get when you walk into a room and get a different lovely smell that hits your senses. There is nothing else like it.
Brogan is a BoXession member, and owns her own business, Cherrytree Melts. You will always hear me speak highly of small businesses; it is a passion of mine to support them every way I can. Don’t forget if you are reading this, we do a Small Business Saturday every week! This is where I first saw Brogan post about her wax melts too, so when she asked us if we would like to trial and review some I begged the other ladies if I could do this for her personally.
I think I was more excited about these as she specifically asked me which scents I like, and I love anything sweet. I love candyfloss and I use Snow Fairy just because it smells like sweets every time I shower. Talking of which, Cherrytree Melts have their own version of this very popular fragrance but it was out of stock at the time mine were posted. Brogan has so kindly offered that once they are back in stock she will send some to me, now that is what I call the personal service!
If you missed my unboxing, sadly I can’t offer smell-o-vision, but I can offer you to re watch it below on our YouTube Channel! Off you pop…
So what did I receive?
- Chunky Snap Bar – Blueberry & Vanilla – £2.40
- 3 x 2oz melt tubs – Purple Rain, Juicy Fruit Gum, and Blue Cotton Candy – £2 each or 6 for £10
- Heart Waffle – Right Butter (S & Glory) – £2 each or 6 for £10
- 2 x Shape packs – Fluffy Pink Candy and Aura for Her – £2 each or 6 for £10
I specifically asked for these fragrances, but Brogan sells so many different ones. Here is a sample of her fragrance list:
- Blueberry and Vanilla
- Frozen Margarita
- Lime Cooler
- Juicy Grapefruit
- Lemon Sherbet
- Citrus Linen
- Tropical Pop
- Hawaiian Tropic
- Coco Loco
- Juicy Fruits Gum
- Alien Type
- Turkish Delight
- Skittlez
- Parma Violets
- Eton Mess
- Strawberry Trifle
- Snow Faerie
- Jelly Glazed Donut
- Dr Pop
- Sweet Barista
- Italian Waffle Cookies
- Hot Baked Apple Pie
- Banana Milkshake
That is just a FRACTION of the fragrances she sells, if I was to put them all in this review you would still be scrolling on. These soy wax melts are handmade by Brogan, and she only charges postage at what it costs, and not an inflated price.
Here comes the testing, yay!
The first of these I tested was Juicy Fruit Gum. It smells just like the famous chewing gum. I have not had any of that in years, since I was a teen. It really takes you back when a scent jogs your memory like that.
The next one was purple rain… I did not know it was a popular drink, Brogan told me and then all of the BoXession ladies laughed at me for my innocence. I have 2 children, I have not been out drinking in years. I love this purely because it is purple, and it smells purple. It is so strong, but I love strong scents that last and linger.
I haven’t yet tested blue cotton candy, but no doubt I will love that!
Sometimes I wonder how I got through life, I cannot believe I did not click in my live that the green butterflies aptly named ‘Aura for her’ were a smellalike for the ever popular perfume. I have a smaller pineapple shape warmer in my kitchen, the plug-in style, so I popped one of these in there first.
For a tiny melt, and I have a massive kitchen (3 rooms knocked into one area), this packed a punch! I will also be using the fluffy pink candy in here, but after 48 hours I can still smell the scent from Aura, and have no need to change it yet.
These have to be my favourite, purely because I find them very easy to use. I will also mention that snap bars by some well named shop brands cost in the region of £7, and these are a TINY £2.40! Bargain indeed.
I melted one of these in my son, Joel’s room. Like his mum, he loves anything sweet or cake like. He barely lets me into his room as it is his gaming paradise, but I can tell you it was strong enough to rid the smell of stinky socks, ha!
I could not even think of the name for this as I hit a blank, of course it is the shape of a breakfast waffle. I broke this in half and warmed in my bedroom. I have bought lots of beauty products from this well-known brand, and this smells exactly like it. This I could smell in the entire of the upstairs of my house even the next morning after I had turned off the warmer!
My Verdict?
I will be placing another order from Cherrytree Melts, absolutely! I want so many Snow Faerie snap bars to last me a year in fact, ha! A little bird told me that they smell exactly like my favourite scent.
These melts are amazing for the price, you are supporting one lady who puts her love and heart into her business. You would be absolutely crazy not to order these, stock up ladies. Order them for gifts, Christmas, Birthday and Teacher presents too. Need I mention it is my Birthday next month too?
The link to order from the very lovely Brogan is below, and again at the top…
Mel x
0 comments on “CherryTree Melts Review by Mel – September 2018”Add yours → |
Quality management system according to
ITAF 16949:2016
certified compliant with certification requirements of the automotive industry
certificate registry no. 71 111 J 036/1
(IATF-Registration-No. 0322836) and
certificate registry no. 71 111 J 036/2
(IATF-Registration-No. 0322838).
Economic activities are associated with energy consumption and interference in the environment. For this reason the for industrial production necessary technology and their peripherals must be designed in such a manner so as not to endanger humans or the surrounding environment and that the energy required is kept to a minimum. The Johann Hay GmbH & Co. KG Automobiltechnik acknowledges this 21st century strategic task by implementing both a globally standard integrated management system, DIN EN ISO 14001 and the European-wide standard DIN EN ISO 50001.
The energy and environmental policy embodies the principals of our various efforts. As part of our corporate guidelines it is binding for all our employees. Our internal corporate energy and environmental protection objectives and the energy efficiency and environmental protection programs necessary to achieve these objectives are derived from it. The Johann Hay GmbH & Co. KG Automobiltechnik energy and environmental protection are based on the following energy management and environmental protection guidelines: |
SpaceX Capsule Runs into Trouble in Orbit
After a successful Friday liftoff, SpaceX's privately-owned Falcon 9 rocket, which is carrying the Dragon resupply capsule to the International Space Station, encountered trouble in orbit.
Nine minutes after launch, the rocket maker's billionaire founder, Elon Musk, reported a problem with the Dragon spacecraft's maneuvering thrusters.
After the capsule separated from the second stage of the launch rocket and reached Earth's orbit, three of four sets of thrusters did not activate normally..
Must have been those side trips in Connecticut. |
The Twelve Buddhas
The sutra The Twelve Buddhas (Skt. Dvādaśabuddhaka; Tib. སངས་རྒྱས་བཅུ་གཉིས་པ།, Wyl. sangs rgyas bcu gnyis pa) opens at Rajagriha with a dialogue between the Buddha Shakyamuni and the bodhisattva Maitreya about the eastern buddhafield of a buddha whose abbreviated name is King of Jewels. This buddha prophesies that when he passes into complete nirvana, the bodhisattva Incomparable will take his place as a buddha whose abbreviated name is Victory Banner King. Shakyamuni then provides the names of the remaining ten tathagatas, locating them in the ten directions surrounding Victory Banner King’s buddhafield Full of Pearls. After listing the full set of names of these twelve buddhas and their directional relationship to Victory Banner King, the Buddha Shakyamuni provides an accompanying mantra-dharani and closes with a set of thirty-seven verses outlining the benefits of remembering the names of these buddhas.
There are three versions of text with this title that are included in the General Sūtra Section, Toh 273, the Action Tantra Collection, Toh 511, and the Compendium of Incantations, Toh 853 of the Dergé Kangyur.[1]
Text
The Tibetan translation of this sutra can be found in the General Sutra section of the Tibetan Kangyur, Toh 273
- English translation:
The Twelve Buddhas |
- Created by Sebastian Kummer, last modified by Manfred Kutas on Mar 28, 2019
Until version 2.2.x Z-Push was officially only distributed as a tarball. This source tarball will be further maintained for Z-Push 2.3, but it's highly recommended to use the newly available repositories and packages instead. If you are looking for the tarball, scroll to the end of the page. Starting with Z-Push 2.4.0 there won't be tarball releases.
Repository
With the release of Z-Push 2.3 a public repository is available.
Stages
There are different stages of packages available:
Distributions
The final repository contains builds for the following distributions/architectures:
PHP 5.4 required
Z-Push 2.3, 2.4 and 2.5 require at least PHP 5.4. Due to this, packages for older distributions are not available.
Usage of repositories together with Zarafa/Kopano
Even though the the Z-Push Kopano backend is included in all of the above repositories, this backend can only be used in distributions that are also supported by Kopano/Zarafa and therefore provide php-mapi package.
URL
The base URL of the repository is:<stage>/<distribution>/
To e.g. add the stable repository for Ubuntu 16.04 use:
deb /
Packages
Main packages
* GAB = Global Address Book.
Other Packages
Installation
This will guide you through the basic installation on example of Kopano/Zarafa.
The examples below show how to add the repository and install Z-Push using shared-memory and the file state machine (same as with Z-Push 2.2.x).
z-push-top and
z-push-admin can be executed from any location (as
root).
The main directory is
/usr/share/z-push, the configuration files are located in
/etc/z-push.
If you use Kopano on a different host or ZCP you need to adjust the
MAPI_SERVER in
/etc/z-push/kopano.conf.php to fit your environment.
Debian und Ubuntu based systems
Add repository
First of all, the repository needs to be added to your distribution.
E.g. for stable releases on Debian 8, create a new file in
/etc/apt/sources.list.d/z-push.list with the content:
deb /
Then, download the repository key and it to the keychain.
wget -qO - | sudo apt-key add -
Install packages from repository
Assuming that Apache is your webserver, run:
sudo apt-get update
Then:
sudo apt-get install z-push-kopano z-push-config-apache
RHEL based systems
Add repository
First of all, the repository needs to be added to your distribution.
For the final releases on CentOS 7, create a new file in
/etc/yum.repos.d/z-push.repo with the content:
[z-push]
name=Z-Push noarch Enterprise Linux 7 - $basearch
baseurl=
failovermethod=priority
enabled=1
gpgcheck=0
Update the package list:
yum update
Note: If you are using RHEL_6_PHP_56 or RHEL_7_PHP_56 repository and memcached for inter process communication, make sure you have Remis repository enabled.
Install packages from repository
Assuming that Apache is your webserver and you want to install basic Z-Push with the Kopano backend, run:
yum install z-push-common z-push-config-apache z-push-backend-kopano z-push-ipc-sharedmemory
From Source
If you really want to install from the source tarball, the download is available here:
For information on how to install from source, please consult the INSTALL file in the tarballs main directory.
Instead of using the tarball or packages you can also use Z-Push from our GIT. See how to get the latest Z-Push code from GIT.
Speed optimizations
Opcache
Please check if your OS already has or is compatible with PHP opcache. This increases performance a lot as the PHP is compiled and cached. More information can be found here:
To check your opcache usage have a look at this script:
States
The file state machine is used by default. It's the easiest to setup and fits most user profiles. As the states are just files they can easily be backup-ed and maintained.
There are a few downsides to the file state-machine, e.g. they are not clusterable. Some admins use NFS to share the states between several machines, which is required if you run several z-push systems and users can connect to any of them (like with a round-robin load balancer without session stickiness). NFS works but has some issues with stability. In this scenario we strongly recommend the usage of the sql state machine.
More about state machines here: State Machines
Inter process communication (IPC)
By default Z-Push installs the shared-memory IPC provider. It's the easiest to setup and a well fit for the most installations.
There are downsides using shared-memory IPC:
- PHP memory usage per request is about 5 to 10 MB higher than when using the memcache IPC provider
- It's not clusterable. If you use several z-push servers with shared states (like described above) the IPC data needs to be shared between these machines as well. The Shared-memory IPC doesn't allow that.
- It doesn't scale for hundreds of users.
You should use the memcache IPC provider in these cases. It requires the installation of a central memcache service, where all Z-Push instances connect to. It's a lightweight service that only requires a few MB of RAM (32 MB should be enough for most cases). You can install it on one of the Z-Push hosts or setup a dedicated machine (ideally with fail over).
It's not ideal if the IPC data is lost (e.g. when restarting the memcache service), but it's not a big problem either. Within a few requests the required data is built up again.
If your Z-Push server is running out of memory handling Z-Push requests, you should immediately switch to memcache IPC (can be running on the same system). There will be no downtime for users.
Related configuration topics
- No labels |
Similar.
Smart, clear-eyed, and irreverent, Unspeakable Things is a fresh look at gender and power in the twenty-first century, which asks difficult questions about dissent and desire, money and masculinity, sexual violence, menial work, mental health, queer politics, and the Internet.
Celebrated journalist and activist Laurie Penny draws on a broad history of feminist thought and her own experience in radical subcultures in America and Britain to take on cultural phenomena from economic justice and the Occupy movement to online dating and freedom of speech. Unspeakable Things is a book that is eye-opening not only in the critique it provides, but also in the alternatives it imagines.
.
Finally, What Is Marriage? decisively answers common objections: that the historic view is rooted in bigotry, like laws forbidding interracial marriage; that it is callous to people’s needs; that it can’t show the harm of recognizing same-sex couplings, or the point of recognizing infertile ones; and that it treats a mere “social construct” as if it were natural, or an unreasoned religious view as if it were rational.
If the marriage debate in America is decided soon, it will be with this book’s help or despite its powerful arguments..
From the Trade Paperback edition...
THE ART OF WAR
NICHOLAS MACHIAVEL'S PRINCE
DISCOURSES ON THE FIRST DECADE OF
HISTORY OF FLORENCE AND OF THE AFFAIRS OF ITALY |
Ojai production of '33 Variations' offers warmth, humor
“33 Variations” has its own set of movements, from contemporary times to Beethoven’s era and back. Moises Kaufman’s own clever variation of a plot begins with Katherine Brandt, a musicologist intent on discovering the roots of one of the famous composer’s works, “Diabelli Variations,” and brings an impassioned Beethoven onto the stage as a man obsessed with the prospect of turning a musical whim into a memorable set of variations.
To accomplish the multi-century transformations, director Richard Camp has gathered a committed cast that can skim from one century to another while exploring the challenges that the musicologist and the composer face. Both are consumed with their work, and both are ultimately hindered by life-altering health problems, the scientist with a withering disease and the composer with his gradual loss of hearing.
As serious as the physical barriers are to their work, both persist through determination not to let such impediments stop the creative element in their lives.
If the struggles make “Variations” sound desperately sad, that is not what Kaufman has written or what the cast delivers. There is as much warmth and humor in the play as there is pain and sadness, with the former definitely winning the battle.
Tracey Williams Sutton returns to the Ojai stage as a single-minded soul driven by the puzzle Beethoven left with his “Variations,” and Cecil Sutton, in real life Williams’ husband, is the dynamic, grumpy and exuberant — all at appropriate times — composer. The two are the focus of the play and make both characters vivid and, crucially, vulnerable.
The cast around them helps deliver its own variations that help the play run the gamut of emotions. Lynn Van Emmerik as Gertrude Ladenburger, the librarian at Beethoven Haus who helps Katherine find the books that reinforce the scientist’s search, brings humor and Germanic “charm” to her role, and Shayne Bourbon as the composer’s secretary Anton Schindler makes the flustered aide another amusing asset.
Others in the versatile cast are Andra Belknap as Clara Brandt, the daughter who has grown up psychologically distant from her mother but who gradually realizes that there is more than the rigidly scientific side of her mother; Sean Mason as Anton Diabelli, the man who wrote the pallid waltz that he seeks to popularize by getting other composers to add variations; and Devin Dornbos, the “normal guy” who as a nurse understands Clara’s emotional distance from her mother and gradually moves her toward understanding.
Adding the essential piano renditions of snatches of Beethoven’s actual variations is the adept pianist Aaron Embry. Without him, there would be no “play” in the play.
If you go
What: “33 Variations”
Where: Ojai Art Center Theater, 113 S. Montgomery St., Ojai.
Information: or 805-640-8797.
Hours: 7:30 p.m. Fridays and Saturdays, 2 p.m. Sundays through July 15.
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Brake Upgrades: What to Look For When Buying Better BrakesPosted in How To: Suspension Brakes on July 1, 2015
More than likely the brake system on that pickup truck or Jeep you take off-road almost every weekend is the last thing on your mind. On a daily basis, you are probably more concerned with gaining more power, improving traction, and upgrading the suspension of the vehicle.
Face it. You’ve added gobs of weight to the vehicle in the form of heavy duty bumpers, a winch, and any number of other assorted modifications. You have also increased the mass rotating at the ends of those axles with a set of custom wheels and huge tires. Now that rig isn’t as easy to stop on the trail as it was when driven off the showroom floor.
So what’s really important to look for when shopping for a brake upgrade? What are the myths, and what is good information? For this venture, we stuck to disc brakes, and took a look at a few primary points in brake system science to find out what’s important to know.
Swept Area
Swept area is something you see mentioned in specs when describing different disc brake systems. This is also known as pad annulus, or the area of the ring on the brake disc that the pad contacts (or sweeps) as the disc spins. While this is a good way to compare brake systems, it’s not the end-all-be-all to braking performance.
It's a simple method to partly quantify the rotor size. Brake engineers and racing teams use swept area as one of the measurements when building brake systems. However, just because an upgrade rotor is larger in diameter than the factory rotor, doesn’t necessarily mean it has a larger swept area. In many cases, swept area can be more a consequence of the limitations posed by the available space between the hub and the outside dimension of the rotor.
What can be considered more of a benefit from a larger swept area is the fact that the brake pad’s friction block is larger. A larger pad, whether it is wider or longer, will take longer to wear out or overheat. The larger pad can absorb more heat, and will take longer to reach its fade point. The other benefit to a larger pad face is that there is now a larger contact area between the pad and the rotor. This provides a bigger and better path for the rotor to be able to pull heat from the pad and dissipate it into the air.
The reason a large rotor, as well as increased swept area, is a good thing is that the larger the rotor, the larger the pad can be and therefor an increase in brake torque effective radius can be achieved. You really want both.
Vented vs. Non-Vented
Because a brake rotor is basically a heat sink, one of the major jobs that the rotor performs is to dissipate heat into the air in between braking. So unless you’re building a competition-specific vehicle for which overall weight reduction is preferred over longevity or cooling capacity, heavier vehicles, and vehicles that are subject to sustained high-heat intervals, will always benefit from vented rotors.
Venting increases surface area, and the effectiveness of a rotor to manage heat is a function of its overall mass and the total surface area. However, many times a heavier rotor with more mass can absorb the heat created in any given brake interval without rising to as high a temperature as a lighter rotor with less mass.
Some assume that the reason behind a directional vane as compared to a straight vane, or non-directional rotor, is because the directional vanes act as a small blower of sorts and help pump air through the rotor. This is to true to some extent true, but the real physics behind a directional vane’s ability to cool the rotor better is because directional vanes are normally longer than non-directional, and have more surface area. Again, more surface area equals greater cooling efficiency.
One of the biggest misconceptions about brake rotors is the affect of drilling holes in the rotors. We have all seen statements that drilling a bunch of holes in a rotor will make your brakes run cooler and stop faster. This is a myth. In almost all cases, when you drill holes through the rotor, mass is taken away and no appreciable surface area for the rotor to dissipate heat from is gained to make up for the loss of mass helping the rotor absorb heat from the pad. There is also less contact area on the rotor face for the pads to transfer heat to.
However, in some cases a swap to a larger and heavier brake rotor that has been drilled may not be a bad thing. For instance, if you are replacing a much smaller rotor (with a larger, heavier, and thicker rotor, then the gain in mass could outweigh (so to speak) the loss in rotor face surface area.
Brake Pad Materials
What’s the best brake pad? Well, there are something like 300 compounds that go into making a brake pad, so when you hear them called organic, ceramic, or metallic, it’s because that’s the primary ingredient in the pad’s composition. There are also carbon, carbon-ceramic, ferro-carbon, and semi-metallic brake pads. What you can be sure of about your choice of brake pads today is that none of them contain asbestos anymore.
In the U.S., we mostly see ceramic in the aftermarket, and that is primarily due to the fact that they produce a light gray dust that is hard to see, and easy to clean off of the wheels (super important to many vehicle owners). They are also not as noisy as OEM (usually organic) brake pads.
Semi-metallic (or metallic composite) brake pads, for the most part, can provide a higher degree of friction than ceramics and higher resistance to temperature buildup that can cause brake fade and quicker wear. They are in most likelihood, a better choice for heavy vehicles that see hard braking, and they are also fairly good at keeping the noise down.
However, the most important thing to look for in an aftermarket brake pad is a brake pad’s “friction coefficient.” Higher friction number pads are going to be better performers. The trouble is that two pads of the same material from different manufacturers could have very different friction numbers.
An even bigger problem is that many brake pad manufacturers don’t list or won’t provide the friction numbers for a product. This can make comparison-shopping difficult, and it sometimes comes down to trying out a couple of brands until you find what works best for your application.
Moving Calipers Outward
The idea of moving the brake calipers (and essentially the rotors too) farther away from the center of the axle is another thing to discuss. Some brake upgrade kits do this, while others do not. The leverage arm created by the caliper to stop the wheel from turning is a function of the caliper’s pad centerline distance from the axle centerline. The longer the distance, the longer will be the leverage arm.
In very simple terms, the closer you move the caliper to the outside diameter of the tire, the more leverage it has to stop the wheel. This strategy works in consort with rotor diameter, and is the reason why putting the largest rotor on a vehicle that can fit inside the wheel is the biggest single factor to increasing brake torque.
Multi-Piston Calipers
The number of pistons in a brake caliper has nothing to do with determining the static hydraulic clamping force at the calipers. The clamping force is a function of total effective piston area. Whether you have a caliper with two pistons or six pistons on a side, if they both have the same total net effective piston area in square inches, the hydraulic clamping force at any given inlet pressure will be the same.
Upgrading to multiple-piston calipers can provide a braking improvement in a different way, and it all relates to efficiency. First, a caliper with multiple pistons over the length of the pad, as opposed to one single large piston over the length of the pad, will deliver that clamping force in a much better and balanced loading of the pad against the rotor. The benefits of multiple-piston calipers are typically a more confident and positive pedal response, and more even wear over the life of the pad.
Secondly, making a caliper with multiple small pistons that spread their clamping force out over the length of the pad, instead of a single large piston in the center, makes it easier for the caliper manufacturer to build a more rigid caliper with less bulk. The rigidity (or resistance to flexing) creates a much more positive pedal response, offers less wasted pedal travel by minimizing deflection, and more evenly loads the pads. All of which add up to better overall brake performance.
Building Better Brakes
So when building up your off-road truck or that Jeep, we agree that it’s a good idea to pay attention to creating a suspension system that is ideally suited for handling the type of terrain that you want to challenge and your driving style. Absolutely push for more power.
Accessorize and modify your rig with whatever mechanical tools it takes to live out your off-road dream. Just don’t forget the brake system. There’s nothing worse than finding out that you can’t stop having all the fun when all of sudden a tree moves into the middle of the trail.
Sources
805-388-1188
702-826-2400
714-596-4461
602-233-1411 |
Governing bodies
The Audit Committee performs at least the tasks set out in Article 526bis, § 4 of the Company Code.
Current composition of the Audit Committee of the Board of Trustees
The Financial Advisory Committee advises the Board of Trustees on capital investments and reinvestments.
Current composition of the Financial Advisory Committee
Responsibilities?
The Board of Trustees of the FWO is responsible for the allocation of the funds which mainly come from the Flemish Government, and to a lesser extent from the Federal Government. The French Community has a fund analogous to the FWO: the "Fonds de la Recherche Scientifique F.R.S.- FNRS".
The Boards of Trustees of both institutions manage the Federal Fund for Scientific Research (FFWO). The FFWO decides on non-divisible resources and a number of well-defined responsibilities (decisions on common rooms of buildings or certain prizes, donations and legacies).
Current composition of the FFWO Board – Flemish Members
Current composition of the FFWO Board of Trustees – Flemish Members |
Hours after their traditional marriage in Lagos, Nigerian celebrity couple, BankyW and Adesuwa head to South Africa for the final lap of their society wedding.
The couple who had their traditional marriage on November 19 are on their way to South Africa and they shared the attached image as they jet off.
Banky W shared the news on his Instagram page with a photo of him and his wife, Adesua appreciating everyone that graced their traditional wedding ceremony.
He revealed that they are off to Cape town in South Africa for the finale of their love celebration. |
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For many, reaching under their bed and pulling out their used, dusty, by no means-washed Magic Wand whereas scrolling via Crash Pad videos is a well-known solo night time in. However, after we add one other particular person into the bedroom, the Magic Wand stays tucked away gathering dust under the mattress. This elusive American capitalist dream is sought by whatever means mandatory. One resolution is to turn mingle2 dating site into a Russian Mail Order Bride (or at least that option is usually a ticket straight to the wallet of American males). When international mail-order human marriage is involved, it may be a petri-dish-like breeding floor for scams. It’s an unregulated trade with nobody policing it, and there’s additionally no screening process for applicants. Psychological diseases and criminal records may go unchecked.
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Since we’ve got last seen one another as associates three years in the past I’ve lost 30 lbs and gained my self confidence I didn’t have back in highschool and he has observed however extra in a cold and warm side since he’s dating round. We began speaking online as pals once more once we realized we had been back in the same town and determined to satisfy up for lunch. Lunch changed into a four hour dialog realizing how much we had in common now and him texting me an hour after we left saying how great it was seeing me and hanging out to not point out how nice I regarded.
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As a truth, when a girl goes to the club with her legs open looking for for a one-nigh stand, she isn’t significantly in search of for the perfect virgin. That’s simply logic. She desires a guy that provides it to her good. And that is it. Whether or not a virgin can get her content mingle2 login or not is a mystery, so by telling her your contagious virgin illness, you are reducing your possibilities of scoring right away. Not because you are much less of a man (although in her mind you probably are), however as a result of she is not on the lookout for that.
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Of course, a gorgeous look alone doesn’t make a lady desirable. The identical precept applies to Russian girls. In terms of marriage, everyone is in search of more than just exterior magnificence in their associate. In spite of mingle2 everything, such a beauty fades after some time. Russian women learn about this very properly, they usually additionally work on their inside magnificence. Meaning they develop their persona to make them more than just a beautiful factor to have a look at. They will only accomplish this by understanding their roles within the household.
Doug Olds from After Nine Tonight will get why we really feel that nothing could be better than having a husband who understands just how tired and stressed we are. Intercourse is not an obligation. It would not matter how lengthy you’ve been collectively; you need to work on the construct up to get the pay off. That is why Doug suggests making it your primary priority to make your wife really feel safe, sane and safe. Intimacy is all about showing your associate that you are behind them one hundred percent.
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Ask any man from any country, would he like to satisfy a Russian woman a minimum of as soon as in his life – and he will definitely say «yes». Ask him: «Why? », and he will let you know that Russian girl – is a secret he is ready to unravel in any ways. Some males who are more impudent transfer on and dream not solely to fulfill, however to date Russian beauties and make them their wives. It’s tough to find one more nationality that’s as fascinating and required as Russian ladies.
I bought a $125 fold up massage desk. It began out giving one another massages, sometimes resulting in play time and now pretty much any weekend afternoon that I provide her a therapeutic massage, we each know the place it’s going if she says sure. And she or he pretty much at all times says yes. And he mingle2 dating site or she at all times will get a real nice massage too, trigger I like to rub on my child. Horny time doesn’t at all times begin that way, but boy it sure gives every thing a bounce start.
Due to the shortage of accessible men in their very own nation, thousands of Russian and Ukrainian women are broadening their search of a husband to different mingle 2 russiansbrides regions of the world. Being outnumbered by approx. 10 million men, it’s apparent that many Russian ladies will never find their husband of their homeland. |
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Summer reading season is here. So what are you taking (metaphorically or not) to the beach?
Fear not: In this edition of Kirkus on the Standard, David Brown speaks with Kirkus Reviews editor Clay Smith about a couple reading recommendations to get you through the heat.
First up: "The Rise and Fall of Great Powers: A Novel" by Tom Rachman. While the title may sound closer to a textbook, Rachman’s novel is very much nestled in the realm of fiction.
"It’s about a woman named Tooly Zylberberg," Smith says. "The novel begins at a small, sorta nerdy bookstore in Wales. All of a sudden Tooly is contacted by an ex who thinks that he has found out something about someone who was close to her earlier in her life – a lot of awful things have been done to her that she has not remembered. So she becomes this detective of her own life."
"It’s something that has a lot of heart … an adventurous big hearted read," Smith says. He also singles out Rachman for praise in avoiding the dreaded "sophomore slump," praising prior book "The Imperfectionists: A Novel."
As for nonfiction, Smith recommends "Bulletproof Vest: The Ballad of an Outlaw and His Daughter" by Maria Venegas.
"[Venegas] is a Latina writer who is very well acquainted with violence as well as violence south of the border…. her father was a killer, a drunk, and really not a great guy. He abandoned Maria and her family when she was three." The book goes on to explore how Maria questions her father and his decisions 14 years later. Venegas eloquently avoids convicting her father, while at the same time commenting about the state of affairs south of the border. |
When it comes time for makeup, eyeshadow is perhaps the trickiest product on to apply. This is thanks to the fact the eyes have no real limitations. According so that you can the makeup experts, at the same time shape you create creating use of eyeshadows can take one to different realms. Indeed, it was black kohl that transformed Elizabeth Taylor into Cleopatra and Audrey Hepburn into Holly Golightly. Eyeshadows do not nothing but make your eyes look bigger, they can will also add drama and draw attention to your eyes. However, it is any of the trickiest foundation products to apply, the fact that explains why women complete not wear it as often as lipstick. Contest a perfect shade could very well often take some practice, but with a small number of expert tips and techniques, you can do the item in no time.
1. Select the properly eyeshadow form
Eyeshadow comes in so many formulations, each with any kind of unique finish and spot of difficulty. Matte eyeshadows blend easily and probably are perfect for beginners, seeing that they can be each of used for creating a major soft daytime look per a heavy naked nude smoky ocular. If you are probably not so much into eyeliners, you can opt regarding powder eyeshadows that possibly can also be used in the role of eyeliner, as long even though the color is densely pigmented. Used in conjunction with a fine-tipped brush, powder eyeshadow gives any softest, most natural look.
2. Getting the instinctive look
For mild definition, go with a talc matte eye shadow. Choose many that will be neutral into colors primarily because these are the most satisfactory for all eye hues. The major neutral bright colors to use are taupe, beige, moderate wines, ivory, charcoal, browns, and grays. It is always best to successfully choose each medium eye shadow. These units of eyeshadows are thin enough, which means that they provide not need to have massive mixing up. For those who take dark eye colors, brown colours are the best blinds to even use in shop to bring in out that this eye color, making this task more intensified and stated.
3. Consider your tone options
The trusted way into go is very much with darkish brown or black, but innovative options feature other colors such when gray, charcoal, metallics, or to even pastel dashes with color exactly like green, blue, or turquoise, as benefited from on one particular usual holiday collections. Blaze or a lot gives a functional softer research than dark-coloured does. Deep green blinds goes effectively with quite all skin. For those who have in effect complexions offering narrower eyes, metallic sounds are the best. When applied on a the eyes, a titanium shade enjoy silver or else gold has the capability to make all the eyes look bigger in addition to the more wide-awake. You can contrast the idea with some sort of different shade of eyeshadow like shade with bronze, silver with the help of white, plus go desaturated by by making use of lighter colors of all same color or purity family whenever your eyeliner.
4. The specific skin appearance test
When assigning the top rated eyeshadow, the concept is excellent if someone consider your skin firm up first. Usually, there have been eyeshadows which do not always blend well with someone's skin tone. Hence, the site is powerful to want to consider them when choosing eyeshadows.
For example, women in which have gray skin complexions, it would normally be faster if you choose darker shades in eye eye shadows. Choosing lighter shades that pebbles are going to only cook your head look dirty.
5. An rule regarding thumb
Before a person buy personal eyeshadows, in which is most appropriate to think about that charcoal colors show the tendency to produce the affectionate eyes appear on the way to diminish all through size. Available on the other hand, natural light colors provide your view out in line with the out. The govern of thumb when assigning the major shades of all eyeshadow could to make your mind up those which often will add definition keen on your opinion. In reality, eyeshadows typically made to assist you to re-shape the eyes or sometimes any side that encompasses it for instance the browbone section additionally the eyelids.
6. High definition
It can be best regarding smudge one specific soft brown eyeshadow on top of the lid for that wide-eyed look for. If a person want lots more intensity, smudge the head with richer shades setting up from my center associated with the cover then in an outward motion to help to make eyes be bigger.
7. Limit the colors
When searching for the right eyeshadows, the program is absolute best not buy too plenty of shades, in fact if these individuals are always neutral colors. Using these kind of all as one will nevertheless be very unproductive. Best related to all, put together not take ownership of eyeshadows in which it will sketch too very attention for you to your composition as in fact as your lids. In the end, your focus will wind up as taken because granted. Therefore, it definitely is better to actually not conclude shades of pastel brilliant colored car like and people today that become frosted. Indeed, choosing this particular best pigments for your eyes may be amazingly tedious needs very much more practice yet still in time, you am going to soon exist expert to it. Using the end, projection high-definition eyes ought to be an breeze. |
Hi Kylie, As much as I would like to,I'm not going myself but I know some people from NZ who are. Interested? I'm going to the IXth International Asparagus Symposium in WAshington in July instead. Dr Peter Falloon (Christchurch) is a colleague of mine and will be giving a paper there. Wade Elmer (really neat guy) is giving a paper at the PP Conference on Fusarium asparagus in Australasia and should be really interesting. I will be meeting him in the US. have fun! Lesley McK |
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Doctor insights on:
Dilaudid Dose
1
Acetaminophen/hydrocodone 5/500 maximum recommended doses?
2
Would Ultram (tramadol) ease hydrocodone withdrawals?
3
What is the max dose for morphine sulfate -30 mg- every day?
Depends: It depends if you are on narcotics and are narcotic tolerant, I have seen patients on morphine more than 100 mg three times a day. ...Read more
4
Is lorazepam 0.5 mg or Xanax (alprazolam) .25 mg stronger?
Which is stronger: About the same.Get a more detailed answer ›
Can you take 75 mg diphenhydramine HCl (tylenol (acetaminophen) simply sleep) with .5 mg diazepam (valium)?
9
10
Is toprol (metoprolol) 50 mg XR a large dose?
No: Toprol (metoprolol) doses can range from 25-400 mg. The question though is what "size" fits you. ...Read more
11
Could Ultram (tramadol) ease hydrocodone withdrawals?
Yes: Tramadol is a weak opioid and therefore would help with hydrocodone withdrawal. ...Read more
12
Is 50mg hydroxyzine equal to 1 mg ativan (lorazepam)?
See below: There is no dosing equivelancy for these medications. They are used for different reason and are not interchangeable. ...Read more
13
Valium 10 mg suppository side effects?
Sedation: Sedation and a drunk like feeling. Possible sleepiness and lack of coordination as well as the discomfort of the insertion itself which should be mild. ...Read more
14
Can you overdose from .5 mg Xanax (alprazolam) taken with 1 mg ativan?
No: Absolutely not , but don't take any medication outside of your doctor's directions. ...Read moreSee 1 more doctor answer
16
Maximum dose of gabapentin a day?
Neurontin (gabapentin): Average is 1, 800mg. Per day. Less if elderly or child or kidney impairment. ...Read moreSee 1 more doctor answer
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Clonazepam .5 mg effect like xanax (alprazolam)?
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How does opana ER 30 mg and Xanax (alprazolam) 0.5 mg be taken together safely? |
The Ernest Orlando Lawrence Award
Live Sciences: For her studies delineating the genetic characteristics of the HIV virus and for her development of the Los Alamos HIV database, a foundation for HIV research for the scientific community.
Back to 2000's Laureates
The Office of Science (SC) is the single largest supporter of basic research in the physical sciences in the United States. |
I can't imagine how I overlooked it. Over the past week I've baked three cakes and one batch of cookies, quilted a twin-size quilt, played in a concert and practiced for another gig, wrapped presents, written the annual holiday letter (and addressed and stuffed 60 copies into envelopes), attended three parties, and hosted one of my own—all in addition to my usual duties teaching class, working at the shelter, and writing reference book entries. I'm sure I managed to fit a blog entry in there somewhere. Didn't I?
I didn't? I guess this craziness will have to do, then. |
Interested in more details on this topic? Click here!
By Paige Tepping free.! |
Equal-Weight ETF Consistently Outperforming S&P 500
May 10th at 8:47am by Tom Lydon
Investors keep a close eye on the S&P 500 and the blue-chip benchmark has climbed to new all-time highs. However, an ETF tracking an equal-weighted version of the S&P 500 has consistently beaten the index, due in part to the outperformance of U.S. mid-cap stocks.
Over the past 10 years, the Guggenheim S&P 500 Equal Weight ETF (NYSEArca: RSP) has out returned on average 10.7%, compared to the 8.0% return of the the SDPR S&P 500 ETF (NYSEArca: SPY). [ETF Chart of the Day: S&P 500]
RSP has gained 17.2% year-to-date, 26.6% the past year, 17.1% the last three years (annualized) and 8.1% the past five years. In comparison, SPY has increased 15.2% year-to-date, 22.3% the past year, 16.0% the last three years and 5.5% the past five years.
“Despite owning mostly large-cap stocks, by equal-weighting them, the portfolio behaves more like a mid-cap fund, with a greater beta and volatility than a large-cap fund,” Morningstar analyst Michael Rawson said in a note on RSP. “Thus, this fund should really be compared with a mid-cap fund and that exposure can be obtained more cheaply. In addition, there may be a slight improvement in return resulting from the strategy’s need to frequently rebalance by selling recent winners and buying recent losers, which results in a forced buy low/sell high approach.”
Next page: Market-cap breakdown |
The site of the original University of Chicago faculty club, which currently houses the University’s Post Office, will be torn down in July as part of an effort to connect the medical campus to the main quad.
Announced at a public meeting on February 27, the demolishment of the building, now known as Ingleside Hall, will accommodate a new pedestrian walkway. Located where East 58th Street comes to a dead end, the new pavement will connect the entrance of the emergency room at Bernard A. Mitchell Hospital with South Ellis Avenue, according to a University news release. Construction for the project is scheduled to begin in July 2013 with expected completion by June 2014.
In addition, 16 parking spaces will be lost as a result of the new pathway. The plan is to relocate them to 59th Street and Drexel Avenue, said University spokesman Jeremy Manier.
The Post Office, the only current occupant of the building, is still searching for a new location on campus. |
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“She’s more beautiful than anyone woman I’ve met/ and she fucking knows it”, roars Amazing Snakeheads’ Dale Barclay on ‘I’m A Vampire’, and you can picture him immediately. You can picture his red face, his bulging eyes, a vein throbbing in his temple, you can hear the spittle flying from the corners of his mouth. The none-more-Glaswegian growl is completely terrifying, bracing, violent, uncompromising, aggressive and howlingly funny and that's just one line. It’s also Amphetamine Ballads in miniature. The quite, quite astonishing debut from the Scottish trio is all of those things and a couple more. It grooves, pounces, kills, spits, prowls, tears, gouges, slinks, seduces, and scares. In a weird way it even charms. This is, in every sense, the debut of the year - compelling from the bashed gong that introduces the urgent ‘I’m a Vampire’ to the slinking, deconstructed blues of ‘Tiger by the Tail’ that sees the album over the finishing line. Musically it’s an open wound of a record, an album slashed from red-raw skin, that draws blood and drips pus. It’s kind of revolting, but you can’t look away because there’s something fascinating and beautiful in the detail.
If this seems hyperbolic - and it should, because it damn well IS - then that’s because Amazing Snakeheads are the kind of band that inspires hyperbole. They make the sort of music that makes you want to smash your head through something, or run and run and run until you collapse shuddering to the ground, probably just around the point the album goes appropriately dark and slow. There’s a glorious melting pot of influences here: the Birthday Party certainly, in their pitch black, barmy intensity, but also Jon Spencer, Fugazi, Big Black, The Velvet Underground, Joy Division and PiL. It’s all rolling bass and steady rhythms fronted by a howling lunatic. It’s a cult waiting to happen - one that will probably end in messy mass suicide and gun battles. If it doesn’t, it could certainly soundtrack a film that does.
Want examples? Okay. Let’s go to Exhibit A, current single ‘Here It Comes Again’, anchored by a completely straightforward, urgent two note bassline, allowing Barclay’s guitar to sketch spiky stabs across the verses, then burst in with the riff across the chorus, pushing everything over the red line. The lyrics are the four words of the title repeated over and over again which, oddly, you don’t even notice on a first listen because they makes so much sense. It’s an exercise in economy, tension and release and it’s unstoppably brilliant. Exhibit B follows straight on. ‘Flatlining’ again hangs from a bone-solid bass part that does much of the work traditionally occupied by guitar on something this mid-tempo and riffy, meaning Barclay can play about 17 different guitar styles, from wah-heavy soloing to skeletal art-school harmonics and big grungy riffs, as if no-one ever told him that’s not how you’re meant to do things. There’s a honking sax part that adds further atmosphere. Unlike most rock guitarists, Barclay knows when not to play, and his absences are the trio’s secret weapon, giving them a tension and sense for dynamics rarely seen in punk bands. When you get to ‘Every Guy Wants To Be Her Baby’, with its blueprint jazz/blues atmosphere and spooky horn parts and Sixties garage-rock wig-out you could weep at how brilliant this is.
Perfection, of course, is dull. Amphetamine Ballads isn’t perfect - once we’re into the last third it’s already blown its load in terms of ideas, and the deranged energy can’t quite be sustained across the whole album. That’s good though. Debut albums shouldn’t be perfect, they should be a bit messy, they should leave room for improvement - which is what Amazing Snakeheads do. Whatever comes next can be a belter, or maybe fail gloriously, either way it will never be boring. In its imperfections Amphetamine Ballads occupies an especially human place. Saviours of rock n’roll? Nah. It doesn’t really need saving, and anyway this lot are far more about destruction. A modern classic? Just maybe.
- 9Marc Burrows's Score |
By Barbara Liston
(Reuters) - U.S. commercial fishermen are throwing away about $1 billion worth of edible fish each year, according to a conservation group which is advocating for incentives to stop the waste.
The quantity of so-called bycatch – that is, fish that wasn't targeted but caught inadvertently – is estimated by the U.S. government at two billion pounds (907,185 tonnes) a year.
The surprise was the quality of the bycatch that often is tossed back into the ocean dead or dying, said marine scientist Amanda Keledjian, author of the report from Oceana, a nonprofit international conservation group.
"We're not just throwing away trash fish. We're throwing away meals," Keledjian said.
Keledjian said fishermen throw away the unintended catch for several reasons, including lack of a permit to fish the species, quotas, size limit laws and the complication of processing an odd fish back at the dock.
The study put a price on the bycatch reported by U.S. fisheries in 2010 and recently compiled by the National Marine Fisheries Service.
T. J. Tate, who until recently headed an organization of 110 red snapper commercial fishing businesses in the Gulf of Mexico, said most commercial fishermen are conservationists at heart and support measures to keep fisheries sustainable.
"What they don't want is to be regulated to death where they can't do what they do," said Tate.
Her group, the Gulf of Mexico Reef Shareholders Alliance, which banded together in 2008 to protect the marine environment, already encourages the landing of red porgy, their typical bycatch, which they promote and sell under their own brand.
The Oceana report said the discarded bycatch included $45 million worth of sea trout from the South Atlantic and Gulf of Mexico, $20 million in sea scallops from the Mid-Atlantic and New England, and $53 million in Pacific halibut from Alaska, which was 25 percent of the landed halibut, according to the report.
Oceana is calling for economic incentives, including the possibility of a bycatch tax, to both bring the bycatch to market to retrieve some value and to encourage the adoption of improved gear to avoid bycatch.
The bycatch of unwanted fish or ocean wildlife was "one of the biggest threats to the health of ocean ecosystems, contributing to overfishing and the decline of fish populations around the world," Oceana said.
(Editing by David Adams and Sandra Maler) |
The lived experiences of late-adolescent female suicide survivors: 'A part of me died'
Willem A. HoffmannI; Chris MyburghII; Marie PoggenpoelIII
IDepartment of Biomedical Sciences, Tshwane University of Technology, South Africa
IIDepartment of Educational Psychology, University of Johannesburg, South Africa
IIIDepartment of Nursing Sciences, University of Johannesburg, South Africa
ABSTRACT
People's thoughts often focus on the suicide victim immediately after a completed suicide. Yet, the real victims of such an event are those individuals who are left behind to cope with the aftermath of the suicide. This phenomenological psychological study explored the lived experiences of late-adolescent suicide survivors, particularly those negative experiences that seemed to worsen in the weeks and months after a significant other's completed suicide. The research participants were five female late-adolescents (aged 17-22 years) who were recruited by means of purposive sampling at a South African tertiary institution and at youth camps. Data collection consisted of collage-facilitated, face-to-face phenomenological interviews. In addition, some participants provided documentary material in the form of personal diaries, letters and poems. The data analysis was conducted according to Giorgi's phenomenological method. The following salient experiences emerged during the data analysis: guilt, self-blame, blaming others or God, anger, loss or restriction of 'self', depression, suboptimal behavioural coping patterns, changes in relationship dynamics, and suicidality. The results of this study can be used by mental health professionals and caregivers to support adolescent suicide survivors effectively, in the midst of their mourning.
Keywords: phenomenology; postvention; psychoeducation; qualitative analysis; suicide aftermath
OPSOMMING
Mense se gedagtes fokus meestal op die selfmoordslagoffer onmiddellik na 'n voltooide selfmoord. Tog is die werklike slagoffers die persone wat agterbly om die lewe na die selfmoord te hanteer. Hierdie fenomenologies-sielkundige studie het die geleefde belewenisse van laat-adolessente oorlewendes ondersoek, spesifiek daardie negatiewe belewenisse wat skynbaar erger word in die weke en maande na 'n betekenisvolle ander se voltooide selfmoord. Die navorsingsdeelnemers was vyf vroulike laat-adolessente (17-22 jaar oud) wat gewerf is deur middel van doelgerigte selektering by 'n Suid-Afrikaanse tersiêre instelling en jeugkampe. Data-insameling het geskied aan die hand van collage-gefasiliteerde, aangesig-tot-aangesig fenomenologiese onderhoude. Sommige deelnemers het addisionele dokumente in die vorm van persoonlike dagboeke, briewe en gedigte beskikbaar gestel vir data-analise. Die data is geanaliseer volgens Giorgi se fenomenologiese metode. Die volgende belewenisse het na vore getree tydens die data-analise: skuldgevoelens, self-blaam/spyt, blameer ander/God, woede, verlies/inperking van 'self', depressie, sub-optimale gedragshanteringspatrone, veranderinge in verhoudingsdinamika, en selfmoordneigings. Die resultate van hierdie studie kan deur geestesgesondheidwerkers en versorgers aangewend word om adolessente selfmoordagtergeblewenes effektief te ondersteun in die rouproses.
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Correspondence:
Willem Hoffmann
Department of Biomedical Sciences, Tshwane University of Technology
Private Bag X680
Pretoria 0001
South Africa
Received: 31 Aug. 2009
Accepted: 25 Feb. 2010
Published: 08 June 2010 |
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Colonel Jimmy & The Blackfish offer no apologies with their self-titled, self-released debut. With a fast-growing grassroots fan base reaching world wide, this 5-piece outlaw country band is known for ignoring standards and has carved out a niche as a hard-driving, over-sexed gang of murderous misfits. CJBF's musical roots are planted firmly in the moonshine-fueled hellbilly tradition with lyrics rarely offering a moral value yet cleverly composed to convince us to be comfortable with debauchery.
A must-have CD for any drinking event, campfire, or road trip.Track list: |
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using with GIMP Rated 5 out of 5 stars
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Melissa has been working for Shine Lawyers in personal injuries law for almost 13 years. From her beginnings in admin to working her way up to her current role as branch manager, Melissa has seen every step of the process and understands how it works. She specialises in helping clients through a difficult time in their lives when they have sustained injuries through no fault of their own. With Melissa’s help, clients can secure compensation in a timely manner for their own futures and those of their families.
Melissa aims to help those who may not have a voice and to stand up for what is right. She volunteers at the Sunshine Coast Community Legal Centre and is a member of the QLD Law Society and the Sunshine Coast Law Association.
For more information about Melissa and how she can help you, contact our Maroochydore team. |
Jillian Leather Reclining Sofa & Set Rylan 82" Upholstered Tufted Sofa in Taranto Dove photo frame. Tillary® 6-Piece Sectional - Tufted Bathroom Furniture & Decor PB Comfort Roll Arm Leather Sleeper Sofa $3,099 – $3,499 Sale $2,168.99 – $3,499 Dewas One of a Kind Rugs My Wishlist | Financing | Testimonials | Employment | Hank's Event Rental Fishing BLOG Taylor Upholstered Sofa in Howell Mist Natuzzi Editions C046 Energia Reclining Leather Sofa | Adjustable Headrest Look for Sofas & Couches PB Parties Casual Dining Room Settings Serving Trays DIMENSIONS: 82W x 33H x 38D Furniture Covers & Care Vento Addresses in the following State Codes AK, HI, AE, AP, AA, PR, GU, MP, PW, AS, VI, FM and APO/FPO addresses with U.S. ZIP Codes will ship for free with value shipping. You will see this noted in checkout. Height including back cushions: 31 1/2 ", Width: 67 3/8 ", Depth: 38 5/8 " Height including back cushions: 80 cm, Width: 171 cm, Depth: 98 cm More options Toronto Leather Sofa & Set Home Theater Systems Galactica Black Faux Leather Loveseat Contract division Imprint All Wall Art 625 Italian Leather Sectional, RHFC, Pumpkin, Add Ottoman American Casual Ladson Great Room Sofa 77638 Remington Sofa Collection Organic Jaffna Leather Sofa & Set Preston Leather Sofa Set $4,797 sale Soap & Facial Cleansers Rooms We Love Joint Health Stationary Sectional Bunk Up Sort By: Grayson Corner Wedge, Chestnut Gwyneth Sleeper Sofa (Queen) (Custom) Browse By Natuzzi Editions C021 Eleganza Leather Sofa Shop for 7 Piece Dining Rooms San Lorenzo Sectional Wall Units View Online Catalog $496 Market Price $699 Save 29% Sell on Houzz Robroy Leather Sofa & Set $999 – $1,299 Sale $659.99 – $1,299 $1,492.25 platinum wood furniture 4 Pc Sectional Sofa Solid Rugs Only 2 Left Houston Contemporary ... Traditional ... Western ... Casual ... Your style is your choice! Urban 3-Piece L-Shaped Sectional - Heathered Tweed For Recreation. Pay Your Bill $2,899.00 Weight Loss & Nutrition Roxie Power 5-Piece Home Theater Reclining Sectional with LED Cupholders and Ground Lighting Furniture Import & Export Inc. (5) DIMENSIONS: 87W x 35H x 40D Sofa + Sectional Collections 2-4 Weeks (Quick-Ship) (81) $1799.99 Online Price $1,842.90 Flushmounts Kmart.com Vanities and Benches Cortesi Home Contemporary Miami Genuine Leather Sectional Sofa with Right Chaise Lounge, Cream Canisters and Jars
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Bargain | images of brown leather sofas with cushions |
I’ve got a quick review for you today of something that fits into the tools category and it’s something that can be used around the home for many things and for computer work of course. JawayTool has sent me over their 127 piece heat shrink tubing assortment kit and it’s well worth the cost, it’s much cheaper that I can get locally for sure. I use heat shrink tubing for many things, not just wiring, you’d be surprised at how useful it is really. Read on to learn more…
Specifications and Features
On the top of the box is a paper insert with what the product is on the top or front but when you open the box the back side of the paper has a diagram that corresponds to the compartments in the box with labels so you know which tube is which size and where it is in the box. The box has seven sections or compartments in it, five large ones and one that is divided into two that holds the smaller sizes of tubing.
I use heat shrink tubing for many things, not just wiring. For example my son recently broke the strap on his umbrella so I grabbed some extra paracord I had floating around and fashioned him a strap but then I used some heat shrink tubing to seal the two ends together making it look nicer and help to keep it together. The tubing is very simple to use, you don’t need a lot of heat, just a lighter will work to shrink the tubing to size.
Conclusion
The jawayTool 127 piece heat shrink tubing kit is a great product, I like it a lot, and I know it will come in handy for me. Sure it might take me a while to use all of it, but I will use it for many things.
I buy heat shrink tubing locally at Radio Shack and it’s about five dollars for 12 assorted sized pieces so the price of this kit is much cheaper and you get a whole lot more for the price. Here you get 127 pieces for eight dollars and it’s the same quality, it’s well worth it in my opinion and you even get a nice little carrying box.
I can easily recommend this product, it’s more than worth it and it’s just really useful for much more than just wiring.
Pros:
+Inexpensive compared to others
+Nice large assortment
+Includes carrying box
Cons:
-None that I could find
Disclosure: This product was given to us for review by the company for review purposes only, and is not considered by us as payment for the review.
To learn more about our review policy please visit this page HERE. |
$13.95
Featuring Waterproof Paper Pottery which is ethically handmade from paper lined with natural rubber. The pots are completely waterproof internally with a protective repellant layer outside. Perfect for nestling a standard nursery planter inside or fill with water to display a floral arrangement.
Paper Pottery is ethically hand-made in Sri Lanka using only sustainable and recycled materials. Paper Pottery is waterproof, unbreakable, light weight, plastic-free and beautifully versatile.
The small size is 11cm x 11cm and suits a standard 100mm nursery planter.
INCLUSIONS: This listing is for the planter only. Plants available separately. |
Original URL:
Kao Challengers
Cheats for Kao Challengers on PlayStation 2 are not yet available. This may be for several reasons...there are no cheats, we have not had a chance to put them up yet, or the game is not yet released. If you know that there are good Kao Challengers cheats feel free to submit them. |
Mii Electric
Electric cars are popping up all over the place, and since the 2030 ban on petrol and diesel cars was recently announced, you can expect the next nine years to be jam-packed with them.
Many electric cars were initially conceived with internal combustion only in mind and have then been retro-designed with batteries and motors whilst some recent models have the architecture to accommodate both fossil fuels and electric motors. As development moves forwards we’ll see more and more electric cars built from the ground up like VW’s ID range. This is the Seat Mii electric; it’s been a familiar sight on our streets since 2012 with a petrol engine so it definitely falls into the former category.
e-up! – it’s Mii Citigo!
The Mii was launched as part of a three pronged attack on the city-car segment by VAG along with sister cars VW’s up! & Skoda’s Citigo. The trio have gone in quite different directions recently, though. The Citigo was unceremoniously shown the exit door last year and whilst the up! does a rather excellent line in GTI littleness, it was also the first to be introduced as an electric model – the e-up! – way back in 2013.
The electric up! has proved popular, so popular in fact that you currently can’t have one. No, seriously – click onto VW UK’s website and at time of writing, the only electric Volkswagens you can configure are the ID.3 & ID.4. VW promise the Yorkshire-friendly e-up! will be back, they just need to deal with the orders they’ve already got.
What’s new in the Mii electric?
That leaves the Seat Mii electric as the last electric man standing, then – for now, anyway. It’s had a recent refresh to mark the fact it’s throwing off its internal combustion shackles. There’s a new dashboard, 16”, aerodynamic alloy wheels and illuminated badges to make it really stand out.
Choose your colour, that’s it
Speccing a Seat Mii electric couldn’t be any easier. It’s 5-door only, one trim level, one power output, heated cloth seats only; literally all you do is choose the colour you want, and metallic paint is a no-cost option. There’s actually more decision making whilst buying your next mobile phone.
How much is the Seat Mii electric?
The Mii electric costs a little bit more than a mobile phone, though, even the latest iPhone. At £19,800 including the government’s £3,000 grant, it’s certainly not bargain basement motoring, but when you consider that the Mini electric starts at over £25k, it’s definitely competitive.
No huge infotainment screen?
It may have a striking new dashboard, but inside the Mii electric is pared back about as far as modern cars go. The most obvious omission is large central infotainment system poking out of the dash, touchscreen or otherwise. There’s a small screen that shows what radio station’s on and not much more, but if you want to use sat-nav or scroll through the songs on your phone, there’s a cradle with incorporated charging point and your phone with Seat app is then part of the dashboard. These huge screens must use a lot of precious electricity so it’s a sensible move to not have one, but it does kind of beg the question; why make energy-sapping heated seats standard fit?
Mii electric range
With its 82bhp electric motor, the Mii electric is made with city living firmly in mind. Claimed range around town on a full charge is a maximum 222 miles, take it out of its comfort zone and that’ll drop to a claimed 160 miles, and we achieved somewhere near that during our week of driving it around town, in country roads and on motorways.
Charging the Mii electric to the all-important 80% level will only take 4 hours from a 7.2kW charger. If you can find a 40kW charger, that drops to just an hour. If it’s used for what it was designed for, i.e. low mileage, you could realistically charge your Mii electric once every two weeks so you wouldn’t even need a dedicated home charger – a domestic 3-pin would suffice.
Quicker than you might think
You can alter how much power your Mii electric uses with its eco and eco+ modes if you want to extend your range a little bit further and don’t mind giving up some creature comforts in return. Leave it in normal mode and the Mii electric with its 212Nm torque will get from 0-31mph in 3.9s which is entirely respectable. Top speed is only 81mph but at anywhere near that speed you’ll find your batteries shedding charge quite rapidly.
Driver satisfaction probably wasn’t a priority when they designed the Mii electric and there’s little in the way of feedback or cornering ability. Adding 306kg to a little car like this is noticeable and it takes bumps heavily, but on a positive note, the centre of gravity is far lower. On the whole, though, it really is about getting from A to B with minimum fuss whilst using as little energy as possible.
Should I buy a Mii electric?
With some very attractive ground-up electric designs like the cutesy Honda E now available, the Mii electric does lack outright visual appeal. It’s got a lot to offer in terms of range and quick charging, though, and it’s significantly cheaper than just about all of the competition.
By Ben Harrington
Seat Mii Electric Specifications:
Battery – 36.8kWh electric, Transmission – auto only, Layout – Front engine, FWD, Power – 82bhp, Torque – 212Nm, Emissions – N/A, Economy – N/A, Range – 160 miles combined WLTP, Maximum Speed – 81 mph, Acceleration – 11.9s 0-62mph, Price – £19,800 OTR with £3,000 government grant |
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As of this writing, the economizer has been built, pressure tested and installed in the prototype vehicle. Its performance as a heat exchanger has not yet been tested. Described herein is the theoretical modeling, design and fabrication of the economizer units. Future plans include rigorous road testing to verify the model and to identify possible modifications for a second-generation economizer.
Design
The economizer is required to vaporize and, if possible, superheat liquid nitrogen at mass flow rates of up to 300 g/s. It must not produce excessive pressure drop on either the tube- or shell-side fluids. The economizer must also be safe in both normal operations and during an accident.
For the design of the economizer, a variant of the shell-and-tube heat exchanger has been employed. The tube-side fluid is the incoming liquid nitrogen and the shell-side fluid is the exhaust from the expander. To examine the theoretical limitations on the performance of the economizer, conservation of energy can be applied as shown in Eq. 1.
(1)
For steady state operation, , so the tube-side outlet conditions can be specified by
(2)
To calculate the maximum theoretical performance, assume that the outlet temperature of the shell-side gas is equal to the saturation temperature of the tube-side fluid (~120 K). If the exhaust pressure and temperature of the nitrogen gas is 3 bar, and 270 K respectively, then the maximum enthalpy at the tube-side exit of the economizer, hmax, is 140 kJ/kg, corresponding to a temperature of 155 K. This equates to over 47 kW of steady state heat transfer at the maximum mass flow of 300 g/s, and is 35 K above the saturation temperature of the tube-side fluid. This calculation provides the figure of merit for the performance of the economizer, the heat transfer effectiveness:
(3)
where h1 is -18 kJ/kg and ?hmax is 158 kJ/kg. If more than 50% of maximum performance can be attained (i.e.: ?econ > 0.5), then this should allow the ambient-air heat exchanger to be designed for single phase flow.
Constraints: Due to limited space in the vehicle, the economizer must necessarily be of compact design. As shown in Fig. 7, the two economizer shells are situated in the center of the cargo deck, toward the front of the vehicle. The installation of a second dewar is planned for behind the driver’s seat, so the diameters of the two shells are constrained to be such that they can accommodate this addition. Even though the vehicle is of rugged construction and has good weight bearing capability, low mass components are installed where possible.
Configuration: A shell-and-tube heat exchanger is an obvious choice for compact, yet highly effective duty. The configuration chosen for the economizer is shown in Fig. 8. Though welding is the joining process of choice for tube-to-manifold connections in industrial scale heat exchangers, the available aluminum tubing had a wall thickness of 0.7 mm. This is a difficult size to weld, particularly when using aluminum and when joining to a considerably more massive manifold. This led to the use of compression fittings. Because each tube end has to be accessible to a wrench, the fittings are widely spaced on the manifold, as shown in Fig. 11.
Fig. 11: Manifold showing hole pattern.
Due to this geometric constraint, the tube density for straight tubing is lower than optimum. To increase the length of tube per fitting, a multiple double-back configuration, shown in Fig. 12, was adopted. Each individual tube doubles back on itself four times between the inlet and the outlet, to give five 0.5 m lengths. Each tube has three passes that are in counterflow with the shell-side fluid and two that are in parallel. To achieve an even greater density, each tube was intertwined with its neighbor before installation. There are two economizer units, with 16 tubes in each, totaling 90 m of 6.35 mm diameter tubing. This gives an overall heat transfer area of 1.8 m2.
Fig. 12: Economizer unit showing double-back tube configuration.
Within the shells, the tubes are supported by twelve 3.2 mm rubber disks, or baffles, also shown in Fig. 8 and Fig. 12. These baffles form a seal with both the shell wall and the tubes themselves. Because they have flow passages cut on alternating sides, the baffles also serve to direct the shell-side gas over the tubing in a cross-flow pattern.
Materials and Fabrication: The manifolds are constructed of aluminum 2024-T6 and the tubing is aluminum 6061-T6. Aluminum, besides being readily available, has the advantages of low density, high conductivity, high yield strength at cryogenic temperatures, and excellent machinability. All fittings are either NPT or compression, and are made of aluminum, for comparable thermal expansion. Each shell is constructed of 25.4 mm thick, high-density polyethylene. The inlet, outlet and relief nipples are fused to the main body of the shell.
Structural Integrity: Each economizer is secured to the deck of the vehicle with two nylon straps wrapped around each shell. The shells themselves are pressure rated by the manufacturer to 8.5 bar. The shells are also equipped with one relief valve each, set at a gauge pressure of 4 bar. The aluminum tubing is pressure rated by the manufacturer to near 500 bar.
Each of the four manifolds is designed to withstand an internal pressure of 27 bar, at 77 K. Utilizing the plate bending correlations of Timoshenko, and the yield strength for low-temperature aluminum given by Scott, a factor of safety of 6.7 was obtained. Modifying this result with the ligament efficiency factor given by Harvey for perforated plate stiffness, the final safety factor for the manifolds is 3.4.
When the economizer is operating, the shell will be pressurized to 3 bar. The manifolds will experience a differential pressure of 2 bar acting outward. Because of this, the economizers will see tensile forces in the axial direction of up to 6670 N during normal operations, and 21,600 N in the event of a catastrophic blow-by of the valving in the expander. To counter this, each economizer manifold is retained in place by aluminum brackets bolted together with two 1.9 cm threaded rods.
Modeling
A model was developed for the performance of the economizer, to serve as a design tool. This enabled informed decision-making about such geometric parameters as tube length, number of passes, number of baffles, etc. Pressure drop was not considered as one of the design variables because a blow-down system is being used. It takes no energy and very little additional mass to offset pressure drop in the tube-side of the economizer. For this reason, pressure drop correlations were not included in the model, however, the capability to include them at a later date is built in.
The unique flow arrangement of this heat exchanger does not lend itself to analysis by the ?-Ntu method. Therefore, thermodynamic and heat transfer performance calculated numerically, using a finite differencing scheme. To model the economizer, both the shell-side and tube-side variables were discretized, according to the scheme shown in Fig. 13.
Fig. 13: Element numbering for one economizer tube.
The following assumptions were made in the modeling of the economizer:
* Thermodynamic equilibrium between fluid phases.
* Even flow distribution. There are 32 tubes and two shells, but only one of each is modeled.
* Steady-state operation.
* Fully developed flow.
* Adiabatic shell wall. This is also conservative because heat transfer from the air to the shell-side fluid will increase performance.
* Zero radiation.
* Zero axial conduction.
Across each element of the economizer, an energy balance is performed. That is,
(4)
Note that for this element numbering system, the flow is left-to-right for passes 1, 3 and 5 and right-to-left for passes 2 and 4. For two-phase flow, the heat equation can be written
(5)
For single phase flow, enthalpy is a function of temperature, which is found using a log-mean temperature difference method:
for j = 1,3,5 (6)
for j = 2,4 (7)
where P is the perimeter and L is the element length. is the average overall heat transfer coefficient:
(8)
The tube-side fluid is often of ambiguous phase, so equations of state for the thermodynamic variables are not useful. Instead, a nitrogen properties database is used, where the inputs are the pressure and either the bulk temperature or enthalpy, depending on the phase. The external heat transfer coefficient is evaluated using the Churchill and Bernstein correlation for cylinders in crossflow. The internal heat transfer coefficient for single phase flow is evaluated using Gnielinski’s formula. For two-phase flow, the heat transfer coefficient is found via Kandikar’s correlation.
Results
Results found for the design cruise mass flow of 60 g/s are given in Fig. 14. The shell-side temperature, as well as the tube-side quality as a function of the non-dimensional span are shown. The specific enthalpy at the economizer outlet is 92.3 kJ/kg, giving a heat transfer effectiveness of ?econ = 0.72.
Fig. 14: Quality and temperature profiles through the economizer.
The thermodynamic performance, ?, of the economizer is inversely dependent on the mass flow. To examine why this occurs, note that for this heat exchanger, the shell-side resistance to heat transfer dominates. That is, for any element
(9)
The external heat transfer coefficient scales as , so
(10)
This behavior is displayed by the solid line in Fig. 15. This shows the decreasing value of ?econ, along with the resulting increase in the exit temperature of the shell-side fluid vs. mass flow. The variability in the curve is an artifact of the finite convergence criterion used in the heat transfer simulations and does not reflect any physical phenomena.
Fig. 15: Economizer effectiveness vs. mass flow.
The calculated performance of the economizer meets the original criteria of ?econ ; 0.5 for the majority of its operational envelope, but falls short of the requirement at high mass flows, which will typically occur only in transient bursts. Thermal transients for sub-ambient heat exchangers generally work in favor of performance, so a partial offset of this decrease in effectiveness is expected. To determine whether this is true requires extensive road testing, which was not possible as of this writing because construction on the test-bed vehicle was still in progress. |
Glossary
Downloadable User Guides
Delegate External User Administration | Salesforce
Delegate External User Administration
You can delegate user administration to external users so that they can decide who should access the community.
Available in: Salesforce ClassicAvailable in: Enterprise, Performance, Unlimited, and Developer Editions
User Permissions NeededTo manage external users:“Manage External Users”To create, edit, and delete profiles:“Manage Profiles and Permission Sets”
External users who are delegated administrators can:
Create external usersEdit external usersReset passwords for external usersDeactivate existing external users
You can grant delegated external user administration rights to users with Partner Community, Customer Community Plus, Gold Partner, Enterprise Administration, and Customer Portal Manager licenses.
From Setup, enter Profiles in the Quick Find box, then select Profiles and click a custom profile.
You can’t edit standard profiles. You can add Delegated External User Administrator to a permission set that you assign to a standard profile.
Click Edit.Select Delegated External User Administrator.Click Save.Click Edit in the Delegated External User Profiles related list.Select the profiles you want users with this profile to be able to administer.Click Save.
Consider the following when setting up delegated external user administration.You can also grant delegated administration rights using permission sets.On the profile you’re granting delegated administration rights to:Add the “Create” and “Edit” permissions on contacts so that delegated administrators can create and update contacts related to their account.Set the Accounts and Contacts tab settings to Default On so that delegated administrators can view the Accounts and Contacts tabs and easily manage contacts related to their accounts.
Add the Accounts and Contacts tabs to your community.Set field level security and page layouts so that delegated external user administrators can access only the account and contact fields you specify.
See Also:Create Communities UsersGrant Super User Access to Partner Users in Your Community
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External users who are delegated administrators can:
You can add Delegated External User Administrator to a permission set that you assign to a standard profile.
1-800-NO-SOFTWARE
1-800-667-6389
One Market St.
Suite 300
San Francisco, CA, 94105
United States
If you still can't find what you're looking for try searching H&T. |
Earlier this month I got the chance to travel to New Orleans for some leisure as well as work. If you know me, you know I can't go anywhere or do anything without taking my camera. While in New Orleans I met a beautiful couple who wanted to document their elopement. We walked the city for hours as listened to Katie and Tommy tell me their love story, I also got to hear some history of the beautiful city. Here are some of favorite photos from their session. Enjoy!
To see more of Katie and Tommy's New Orleans elopement CLICK HERE for a SLIDESHOW |
Now,
Now,
New version is finally out!
And I've already updated my mod for it and made a new one :3
I think Toady really needs to address the thihg wirh civillian tools being deadly as fuck.
Mainly because I was adventuring through the catacombs to kill a bandit, accidently found a load of mummies and one got a shot to my brain with a base quality copper boning knife through a high quality bronze helm and a cloak of some description.
No majjyks discovered so far, in either mode.
I found my first vampire. She's twenty years old, according to her profile, and has eleven lines listing all her former entity affiliations. She's an adequate wound dresser and bone doctor. She's put off by authority and tradition. And becomes very rigid when she's angry. What I'm getting at here is that she's basically this chick.
Anyway, I made her my Chief Medical Dwarf. I have too many dwarves, and having one turn up drained of all his blood every now and then is a small price to pay for a medic who doesn't suffer from skill rust.
Not normally, I think. Immigrants are taken from the populations of dwarven fortresses, and necromancers tend to run off and build towers. I guess you could learn the secrets of life and death as an adventurer, and then retire to a fortress, and that would probably work.
Someone should try that with a mod where the playable race has towns.
So, I started playing Dorf Fort in around... 2011? And my only real question is why is it march. This game, man, this game.
Holy crap. In the seven months since I stopped posting here regularly, I've made over 3000 posts on the DF forums. Man I love that place.
Anyway, I've modded a lot more. I now have 4 mods released: Homestuck mod, DBZ mod, SCP mod, and another mod that I just kind of put stuff that I think will be fun that aren't derivative into.
The activation of the world is coming within, like, 10 months. Are you ready???
The devlog. Have you read it? Since 6/6/12, Toady has been working on bringing worldgen activities into gameplay. As of now, he's working on elf sites; he's including ALL creature sites in this update, human, elf, dwarf, goblin, and kobold. Also in the next update is the combat/move speed split, tracking, multi-tile trees, jumping and climbing.
And hopefully birth, aging and succession for all those sites. It's kind of annoying how the humans die off right now if you play a world for a couple of decades. :P
We must dissent!
Oh, that's what you meant.
I thought there was some sort of worldwide DF ARG.
Running is gonna be great
Except when npcs use it to get away from me then it's gonna be stupid bs that shouldn't be in the game
"A man may fish with the worm that hath eat of a king and eat of the fish that hath fed of that worm." -Hamlet
"now you're making steampunk sound like a gender identity or something" - seedy
For people who don't compulsively F5 the bay12games development log page, Tarn "Toady One" Adams has partaken in another interview.
As if there would be people who don't compulsively F5 the dev log. Who could bear to go without the latest news in tree climbing and elven orchards? Could you live with the knowledge that there could be all kinds of new and exciting tree-related hijinks going on in Dr. Adams' pre-release version, and you would not be informed? And if you could do that, could you still call yourself human?
We must dissent!
Is this the best?
(Ebdim7, C#min, G#min...)
Aaah Toady you've given dwarf mode a goal and more purpose and oh my god next version is better in every way imaginable |
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All parishioners are invited to honor Mothers and Fathers from Mother’s Day (May 8) through Father’s Day (June 19) by purchasing baby items from the following wish list. A box will be placed in the Brides Room by the Parish Hall for your generous donations. Diapers—up to size 2, sleepers, gowns, towels/wash cloths, bottles, receiving blankets, baby wash/lotion/shampoo, onesies, new and gently used clothing to 18 months, and any other item of your choice.
Pro-Life Supports New Moms
- A Special Day to Celebrate
- Spring Luncheon and Meeting |
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Firestone Commercial Near Granger, WA: We're Right Here with You
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Wilson’s world
David Wilson is editor of Engineeringtalk and Electronicstalk and associate editor of The Engineer
Jack Robinson had made it a point to study some rather complex, technical subjects during his years at university. So it was no surprise that plenty of recruitment agencies had made contact with him before he even graduated, since his talents were much in demand by those in industry.
After rifling though the list of potential employers who had offered him work, the young engineer eventually decided to join a small engineering firm where he believed he could make an immediate contribution, rather than join a larger company where he might just become another number.
Jack’s decision to take up employment with the smaller outfit proved a very rewarding one — initially at least. The design team he joined was tightly knit yet highly talented, and he was thrilled to see the new products he had helped to design enter the marketplace in less than a year.
For the first few years he spent working for the company, Jack thrived on the entrepreneurial spirit that enabled him to take an increasingly important role developing new systems and software.
Eventually, however, he began to feel stifled by the environment. Like a large shrub in a small pot, he was becoming pot bound — there was no further room to grow and develop and his creative leaves were becoming yellowed by the lack of intellectual stimulation and nutrition.
So the now not-so-young engineer decided to uproot himself and take up a new role as the manager of a design group within a larger company that employed many such design teams that were all working on a number of different projects for a variety of different customers.
The new organisation appeared to offer a lot more room for growth than the smaller company. And for his first few years there, Jack watched as the size and the expertise of his own group of designers multiplied, much to the accolade of the folks on the board of the company.
But just as his own design team flourished, so too did the other design departments within the company. And, backed by considerably more financial fertiliser, they grew so quickly and so substantially that eventually their branches cast long shadows over Jack’s team, which began to pale into insignificance by comparison.
What’s more, as the results of the efforts of the larger engineering groups added evermore sizeable slices of revenue to the bottom line of the company, the management realised that Jack’s engineering team was becoming less financially important.
As a result, his entire design group was eventually sold off as part of a restructuring plan that the management claimed would help them to refocus more appropriately on their ‘core competencies’.
But it’s not all bad news. For his part at least, Jack is a happy camper once more. Although he’s back in a smaller design environment again, this time around he has enough experience to be able to recognise the benefits of it, rather than just its disadvantages.
David Wilson
The Wilson’s World blog also forms part of the Engineeringtalk, Electronicstalk and Manufacturingtalk newsletters. To subscribe, go here for Engineeringtalk, here for Electronicstalk and here for Manufacturingtalk |
Even when two adults love and respect one another, their philosophies and strategies for parenting may be very different. We were each raised with a unique experience based on who we are and how our parents interacted with us. These experiences inform how we approach our parenting journey.
Whether you are co-parenting in the same home or different homes, it is vital for the mental health and success of your child that you agree on the boundaries and expectations you have for your children. The difference in approaches can lead to confusion, depression, anxiety, and defiance on the part of the child.
I am available to meet with you, to help you understand one another’s concerns and perspectives and to help you work together on behalf of your child.
FREE introduction to my book, "8 Keys to Parenting Children With ADHD" when you sign up today! |
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Can I eat this 15 hour old hamburger that's sat out all night?,
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ATS Members have flagged this thread
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reply posted on 6-10-2012 @ 10:54 AM by
Miri08
Have been reading the play by play and am glad that you are still alive. Please update again soon
reply posted on 6-10-2012 @ 10:58 AM by
lurker007
YouTube Link
after seeing this video, if we assume that the composition of burger king and mcdonald's ingredients are similar, I would say 15 hrs is ok, I'd destroy the burger
the above video shows some of mcdonalds food decomposition throughout an 8 week period
and here is a lady who has kept a double cheese burger for 4 years, no mold or mildew!
YouTube Link
reply posted on 6-10-2012 @ 11:10 AM by
Juggernog
reply to
post by JohnPhoenix
Ahh, you should be ok then.
I wouldnt have eaten it but I dont think itll make you sick.
There was no mayo on it or ketchup or pickles..
reply posted on 6-10-2012 @ 11:13 AM by
JohnPhoenix
reply to
post by lurker007
That video of the 4 year old burger and fries was amazing. Thanks for sharing.
I have eaten half the burger and so far feel fine. I will refrigerated the other half either to eat later or give to the hospital if I need to get my tummy pumped. LOL
reply posted on 6-10-2012 @ 03:26 PM by
DocHolidaze
reply to
post by JohnPhoenix
yes, unless it was tainted before it sat out same bacteria and other bad things can devolpe fast, but if it is relitivly clean u should be fine
reply posted on 6-10-2012 @ 05:33 PM by
staple
It is from BK. Throw it away. Fast food is garbage.
I knew a guy that left raw beef out on the counter and would eat it raw or cook some as he needed. He said that because he did it for most his adult life and that his body was used to it. He was built like a tank and other than passing out each night from getting drunk he seemed healthy.
edit on 10/6/2012 by staple because: (no reason given)
reply posted on 6-10-2012 @ 07:09 PM by
seasoul
I've been dumpster diving for quite a few years.
By now I am probably considered a "certified diver."
I'd toss the hamburger in a frying pan, adjust the burner to a maximum flame, standing with a fire extinguisher, cook it until it has a nice charcoal texture.
You should be good to go, honestly.
Bon Appetit
edit on 6-10-2012 by seasoul because: surf or die!
reply posted on 6-10-2012 @ 09:07 PM by
justin366
Fast food is so loaded up with chemicals that you could probably let it sit for 5 years then eat it and be fine.
reply posted on 6-10-2012 @ 09:26 PM by
WeRpeons
During my years at college, living in a dorm with no money to buy food, my room mate and I would probably be fighting for that 15 hour burger.
reply posted on 6-10-2012 @ 09:32 PM by
AthlonSavage
reply to
post by WeRpeons
sure i was on a train once and found a half eaten hot dog and drunk can of coke. i was kinda hungry at the time and thought why let good food go to waste
edit on 6-10-2012 by AthlonSavage because: (no reason given)
reply posted on 6-10-2012 @ 09:52 PM by
riverwild
Why take the chance?
Toss it!
reply posted on 6-10-2012 @ 10:42 PM by
AkumaStreak
So by your logic that paper around the burger is airtight... and only enclosed sterile air?
Riightt.
R.I.P.
Here lies John,
Who died on the jon,
All for a 15-hour old bacteria burger.
reply posted on 6-10-2012 @ 10:44 PM by
AkumaStreak
reply to
post by AkumaStreak
More of your logic -- you want to refrigerate the other half of this toxic waste to consume later? Lol. Did the SHTF and I missed it?!
reply posted on 6-10-2012 @ 11:50 PM by
txjab512
I used to live with a friend of mine in TX. His mother was from Thailand. She would fry chicken and leave it on the kitchen table all day and night! We never got sick. I've eaten pizza that wasn't refrigerated and left out for more than 2 or 3 days and did not get sick. You can usually tell if something has gone bad to the point where it is not edible. I watched my buddies grandfather eat RAW CHICKEN all the time! He was 80 and also from Thailand. Never sick! Might just depend on the person and their immune system. As far as food from a fast food restaurant I wouldn't worry about germs or bacteria. I'd be worried about the chemicals, additives, and preservatives they pump into that crap.
reply posted on 7-10-2012 @ 01:25 AM by
n3mesis
out of necessity i've eaten stuff that would make the average person puke so it's my opinion that the 15 hour old bk burger would be a delicious feast and someone mentioned already it's no more dangerous than a fresh bk burger and i tend to agree because after the nuclear holocaust it's not just cockroaches that'll be left it's all the fast food menu items as well so dig in if you already haven't.
reply posted on 7-10-2012 @ 03:04 AM by
humphreysjim
Yes but you really shouldn't. It won't make you ill I just think you're better than that.
reply posted on 7-10-2012 @ 03:36 AM by
Netties Hermit
reply to
post by JohnPhoenix
OK - it's 7.40pm Sunday night (Aussie time) and you do realise that I'm going to have to come straight back on here and check your posting history first thing in the morning to check if John Phoenix has posted since his Burger King subject No. 1 experiment.
What if you disappear and we're all
???
Will it be a conspiracy?
We can make it into one if not.
We do that good here.
Good luck John Phoenix's tummy tonight.
We want a complete description in the morning.
Actually, strike that.
No we don't.
p.s. just have to say this is the funniest thread I've read in ages.
edit on 7/10/2012 by Netties Hermit because: (no reason given)
reply posted on 7-10-2012 @ 05:02 AM by
Theprimevoyager
i would have eaten it lol
reply posted on 7-10-2012 @ 01:26 PM by
DontTreadOnMe
Many people have crappy immune systems and compromised digestive systems....so where person can dumpster dive and enjoy days old meals...others cannot.
And, you cannot always go by appearance and smell.
We had a power outage...maybe a day in warmish weather.
Had some fresh mozzarella in brine in teh frig....and just didn't want to toss it. Looked good, smelled okay...and I tasted just a little piece ............... I thought I was having a heart attack, and felt like I was dying.
If you've ever had food poisoning.....you know to be wary.
If in doubt, toss it.
YMMV
reply posted on 7-10-2012 @ 01:43 PM by
Juggernog
reply to
post by DontTreadOnMe
Lol, yep.. I remember when I was about 22 and going to a Tech School. I made myself a ham sandwich one July day but forgot to take it out of my glove compartment. I lived in Dallas at the time and the temp was probably 100 plus that day but I was really hungry and ignorant about these things so I ate it and even before our 1 hour lunch was over, I was sitting against the bathroom wall at this school, sweating bullets and puking in the floor.
I left about 20 minutes later and went to my then girlfriends house, now x wife and literally couldnt move for 2 days.
Anyone thats had bad case of the flu, multiply it by 100 and you get food poisoning.
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The Top 10 Quick Tips that will save common household recipes !!!™
2. Get a really good non-stick skillet: if you're tired of having food stick to the bottom of your cookware, then you really need to invest in a great non-stick skillet. The one that I have only set me back $30 and I can cook an egg on it over easy without any oil and not break the yolk . I'm very partial to Caphalon's commercial lines, but definitely check out Anolon, T-Fal, and Farberware as well. Some other very important features are whether the skillet comes with a cover, whether or not the handle gets hot when it cooks, and how long other buyers have found that the non-stick surface lasts for. Make sure that you don't confuse non-stick with hard anodized. Hard anodized is definitely not non-stick and you'll get very frustrated if you get the two mixed up. The additional bonus of a non-stick pan is that cleaning is really easy. Run your pan under water and most extraneous food will slide off easily.
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