id
float64 286
2.87k
⌀ | design
stringlengths 1
92
⌀ | sequence
stringlengths 74
86
| activation_ratio
float64 0.02
60
| folding_subscore
float64 4.86
30
⌀ | num_clusters
float64 51
930
⌀ | ligand
stringclasses 3
values | switch
stringclasses 2
values | kd_off
float64 2.54
1.9k
| kd_on
float64 2.53
1.53k
| kd_fmn
float64 8.14
1.7k
⌀ | kd_no_fmn
float64 8.17
1.72k
⌀ | min_kd_val
float64 2.53
10.3
| ms2_aptamer
stringclasses 128
values | lig_aptamer
stringclasses 59
values | ms2_lig_aptamer
stringclasses 406
values | log_kd_nolig
float64 0.93
7.45
| log_kd_lig
float64 0.93
7.55
| log_kd_nolig_scaled
float64 0
6.43
| log_kd_lig_scaled
float64 -0.16
5.98
| log_AR
float64 -3.72
4.09
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
null | SSTryp B #28 | CUGUACAUCUCGGCCGCCACUGCAACAUGUACACAUGGACAUGUACAUGAGGAUCACCCAUGUGGCAGGACCGGGAGGUGUGCAG | 7.24 | null | 60 | Trp | ON | 191.69 | 26.46 | null | null | 6.72 | ............................................(((((x((xxxx)))))))...................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.......................(((((x((xxxx)))))))...))xxx)))........... | 5.255879 | 3.275634 | 3.350791 | 1.370546 | 1.979621 |
null | Exclusion Tryptophan B 2 | AACAUGAGCACGGCCGCCACUCCAUGAACAUGAGGAUCACCCAUACACAUGAGGAUCACCCAUGUGAGGACCGGGUGUCCAUGUG | 4.27 | null | 160 | Trp | OFF | 56.63 | 13.28 | null | null | 6.72 | ..............................................(((((x((xxxx))))))).................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.........................(((((x((xxxx))))))).))xxx)))........... | 2.586259 | 4.036539 | 0.681171 | 2.131451 | 1.451614 |
null | #03 Exclusion Tryptophan B | CACGAAAGAUCGGCCGCCACUAAUCUAUGUGUACUAGCACAUGAGGAUCACCCAUGUUCUUGCGUUAGGACCGGGAUUGAGCGUG | 0.84 | null | 108 | Trp | OFF | 18.76 | 22.2 | null | null | 6.72 | ......................................(((((x((xxxx)))))))............................ | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.................(((((x((xxxx))))))).........))xxx)))........... | 3.100092 | 2.931727 | 1.195004 | 1.026639 | -0.174353 |
null | Exclusion Tryptophan A 2 | ACAUGACAACAUGAGGAUCACCCAUGUCAUCGAGGACCGGUACGGCCGCCACUCGGUCAAUAUGAUACUUGUCAUGAACAUGAGG | 1.26 | null | 81 | Trp | OFF | 23.46 | 18.68 | null | null | 6.72 | ........(((((x((xxxx))))))).......................................................... | ................................((xxx(((.....)))xxx))................................ | ........(((((x((xxxx))))))).....((xxx(((.....)))xxx))................................ | 2.927453 | 3.155297 | 1.022365 | 1.250209 | 0.231112 |
null | Exclusion Tryptophan B GF13 | UUGUGGCGCUCGGCCGCCACUCCGACAUGAGGAUCACCCAUGUUCUACAUGAGGAUCACCCAUGUGAGGACCGGGAGACACUUCC | 0.99 | null | 101 | Trp | OFF | 103.49 | 104.09 | null | null | 6.72 | ........................(((((x((xxxx))))))).......................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((...(((((x((xxxx))))))).......................))xxx)))........... | 4.645256 | 4.639475 | 2.740168 | 2.734387 | -0.01005 |
null | Same State Tryptophan B GF 18 | AUGGAGACCUCGGCCGCCACUCUCCAUGAGGAUCUCCCAUGUAACAUGAGGAUCACCCAUGUGCUGAGGACCGGGAGGUCCUGAA | 0.88 | null | 58 | Trp | ON | 10.62 | 12 | null | null | 6.72 | ...........................................(((((x((xxxx)))))))....................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((......................(((((x((xxxx)))))))....))xxx)))........... | 2.362739 | 2.484907 | 0.457651 | 0.579818 | -0.127833 |
null | Ex Tryptophan B 19 | CCUAUGCAGUCGGCCGCCACUGAUAACGUUAUCGUUACCUCAGAAACAUGAGGAUCACCCAUGUACAGGACCGGGACUGUAUAGG | 1.19 | null | 80 | Trp | OFF | 15.28 | 12.84 | null | null | 6.72 | .............................................(((((x((xxxx)))))))..................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((........................(((((x((xxxx)))))))..))xxx)))........... | 2.552565 | 2.726545 | 0.647477 | 0.821457 | 0.173953 |
null | Omei Tryp SS B v8 | AGAGCAUUGACGGCCGCCACUCGUGUCACAUGAGGAUCACCCAUGUGACGGGUGAUCGCCCGGUUGAGGACCGGGUCAAUGCUCA | 0.85 | null | 106 | Trp | ON | 9.69 | 11.43 | null | null | 6.72 | ...........................(((((x((xxxx)))))))....................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((......(((((x((xxxx)))))))....................))xxx)))........... | 2.271094 | 2.436241 | 0.366006 | 0.531153 | -0.162519 |
null | Same State - Tryptophan A / A | ACAUGAGGAUCACCCAUGUACGGUAUCAAUCGAGGACCGGUACGGCCGCCACUCGGAAAUAGAAGCGAUUAUUAGUGUUCUUUGU | 1.07 | null | 99 | Trp | ON | 16.24 | 15.12 | null | null | 6.72 | (((((x((xxxx))))))).................................................................. | ................................((xxx(((.....)))xxx))................................ | (((((x((xxxx))))))).............((xxx(((.....)))xxx))................................ | 2.787477 | 2.716018 | 0.882389 | 0.81093 | 0.067659 |
null | TryBS - Mat transfer 6455056 - Unstable 1 | UGGUACUAGGCGGCCGCCACUGGGAGAUACAUGAGGAUCACCCAUGUUUAAUGCCGAGAGGCAACUAGGACCGGGCCUAGUACAU | 4.39 | null | 53 | Trp | ON | 116.53 | 26.53 | null | null | 6.72 | ............................(((((x((xxxx)))))))...................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.......(((((x((xxxx)))))))...................))xxx)))........... | 4.758149 | 3.278276 | 2.853061 | 1.373188 | 1.479329 |
null | Omei Tryp B SS C v6 | AGAGUCUAGUCGGCCGCCACUCAUGUCCAAUGGACAUGAGGAUCACCCAUGUACCGAAGGUACAUGAGGACCGGGACUGGACUCA | 13.11 | null | 85 | Trp | ON | 152.68 | 11.65 | null | null | 6.72 | .................................(((((x((xxxx)))))))................................. | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((............(((((x((xxxx)))))))..............))xxx)))........... | 5.028344 | 2.455306 | 3.123256 | 0.550218 | 2.573375 |
null | Exclusion Tryptophan B GF 25 | AGUUCCAGGUCGGCCGCCACUGGCGUGGCCGGUCCUCGGACUUACAUGAGGAUCACCCAUGUGAACAGGACCGGGACCGCAUGGG | 0.78 | null | 92 | Trp | OFF | 28.68 | 36.88 | null | null | 6.72 | ...........................................(((((x((xxxx)))))))....................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((......................(((((x((xxxx)))))))....))xxx)))........... | 3.607669 | 3.3562 | 1.702581 | 1.451112 | -0.248461 |
null | Ex Tryptophan B 10 | CCUAUGCAGUCGGCCGCCACUGAACAUGAGGAUCACCCAUGUAUAUAAAGAUCCUGAUAUAAUAACAGGACCGGGACUGUAUAGG | 2.62 | null | 65 | Trp | OFF | 156.6 | 59.67 | null | null | 6.72 | .......................(((((x((xxxx)))))))........................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..(((((x((xxxx)))))))........................))xxx)))........... | 4.088829 | 5.053695 | 2.183741 | 3.148607 | 0.963174 |
null | Tryptophan B 6 | GGUUACUCUACGGCCGCCACUGAACAUGAGGAUCACCCAUGUAAUGUUCAGUAGUCUUUAGACAACAGGACCGGGUAGUGUAACC | 1.06 | null | 99 | Trp | ON | 227.63 | 215.43 | null | null | 6.72 | .......................(((((x((xxxx)))))))........................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..(((((x((xxxx)))))))........................))xxx)))........... | 5.427722 | 5.372636 | 3.522633 | 3.467548 | 0.058269 |
null | Tryptophan B 2 | UUAUAUACUACGGCCGCCACUGAACAUGAGGAUCACCCAUGUAAUGUUCAGAUUUUUUUUUUUUACAGGACCGGGUAGAAUUAAA | 1.19 | null | 97 | Trp | ON | 158.58 | 133.38 | null | null | 6.72 | .......................(((((x((xxxx)))))))........................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..(((((x((xxxx)))))))........................))xxx)))........... | 5.066259 | 4.893202 | 3.161171 | 2.988114 | 0.173953 |
null | Ex_TrypA - ViennaApproves | GAUCAAAGAUCACAUGAGGAUCACCCAUGUCGAGGACCGGUACGGCCGCCACUCGCGGCGGUGAAAAUAGAUACAAAGUAUCUAU | 4.47 | null | 89 | Trp | OFF | 347.21 | 77.64 | null | null | 6.72 | ...........(((((x((xxxx)))))))....................................................... | ................................((xxx(((.....)))xxx))................................ | ...........(((((x((xxxx)))))))..((xxx(((.....)))xxx))................................ | 4.352083 | 5.84993 | 2.446995 | 3.944842 | 1.497388 |
null | X-tryptB-ms2@35 | UGGAGUAGGACGGCCGCCACUAUACAAUGUGUAUACAUGAGGAUCACCCAUGUAAUCCUCGGAGAUAGGACCGGGUCAAGUUGUG | 0.94 | null | 231 | Trp | OFF | 50.48 | 53.65 | null | null | 6.72 | ..................................(((((x((xxxx)))))))................................ | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.............(((((x((xxxx))))))).............))xxx)))........... | 3.982481 | 3.921577 | 2.077393 | 2.016489 | -0.061875 |
null | XTryp B #24 | AGAUUCGACACGGCCGCCACUUGGAGUGGCUGCUAGCAUGUUACACAUGAGGAUCACCCAUGUCUAAGGACCGGGUGUUGAGUCU | 5.25 | null | 127 | Trp | OFF | 215.61 | 41.06 | null | null | 6.72 | ............................................(((((x((xxxx)))))))...................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((.......................(((((x((xxxx)))))))...))xxx)))........... | 3.715034 | 5.373471 | 1.809946 | 3.468383 | 1.658228 |
null | Same State Typptophan B GF11 | GUCCUCAUGACGGCCGCCACUAAACAUGAGGAUCACCCAUGUAAUGAUCCAUUAAAUGAUAAUAGUAGGACCGGGUCAAAAUAAA | 0.71 | null | 109 | Trp | ON | 476.93 | 668.64 | null | null | 6.72 | .......................(((((x((xxxx)))))))........................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..(((((x((xxxx)))))))........................))xxx)))........... | 6.16737 | 6.505246 | 4.262282 | 4.600158 | -0.34249 |
null | Exclusion Tryptophan B GF 19 | GAGUAGAGGACGGCCGCCACUGAACAUGAGGAUCACCCAUGUCGUGAUCCGUUACCUAAAGAAGAUAGGACCGGGUCAUGUACUC | 1.05 | null | 113 | Trp | OFF | 28.73 | 27.29 | null | null | 6.72 | .......................(((((x((xxxx)))))))........................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..(((((x((xxxx)))))))........................))xxx)))........... | 3.30652 | 3.357942 | 1.401432 | 1.452854 | 0.04879 |
null | Tryptophan B 7 | GGUUACUCUACGGCCGCCACUGAUAAAUAAUAAACCUGUACAUAAACAUGAGGAUCACCCAUGUACAGGACCGGGUAGUGUAACC | 1.36 | null | 188 | Trp | ON | 32.8 | 24.07 | null | null | 6.72 | .............................................(((((x((xxxx)))))))..................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((........................(((((x((xxxx)))))))..))xxx)))........... | 3.490429 | 3.180966 | 1.58534 | 1.275878 | 0.307485 |
null | Omei Trp Exc B A v13 | AGCACUGUGGCGGCCGCCACUACAUAUAGGGUGGUCAGGCCCAUAAUACAUGAGGAUCACCCAUGUAGGACCGGGCCUCAGUGCA | 0.99 | null | 75 | Trp | OFF | 14.85 | 15.03 | null | null | 6.72 | ...............................................(((((x((xxxx)))))))................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..........................(((((x((xxxx)))))))))xxx)))........... | 2.710048 | 2.698 | 0.80496 | 0.792912 | -0.01005 |
null | Same State - Tryptophan B / A | UAAGUUAGGGCGGCCGCCACUCGAACAUGAGGAUCACCCAUGUAAAUUAAUUAAAGGACAUGAAUGAGGACCGGGCCAAGUUAGA | 1.17 | null | 86 | Trp | ON | 15.71 | 13.4 | null | null | 6.72 | ........................(((((x((xxxx))))))).......................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((...(((((x((xxxx))))))).......................))xxx)))........... | 2.754297 | 2.595255 | 0.849209 | 0.690167 | 0.157004 |
null | Exclusion - Tryptophan B / A | GGAUUAGAGGCGGCCGCCACUGGAACAUGAGGAUCACCCAUGUAGUGCAUGUAAUUAACCUCGAUCAGGACCGGGCCGAUAGUCA | 1.72 | null | 88 | Trp | OFF | 103.25 | 59.94 | null | null | 6.72 | ........................(((((x((xxxx))))))).......................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((...(((((x((xxxx))))))).......................))xxx)))........... | 4.093344 | 4.637153 | 2.188256 | 2.732065 | 0.542324 |
null | 2 | CCGGCCAAUUAGAAAUUAAUUGGCCGGAAACGAGGACCGGUACGGCCGCCACUCGUGGCGGGAGAAACAUGAGGAUCACCCAUGU | 0.65 | null | 87 | Trp | OFF | 25.96 | 40.01 | null | null | 6.72 | ..................................................................(((((x((xxxx))))))) | ................................((xxx(((.....)))xxx))................................ | ................................((xxx(((.....)))xxx)).............(((((x((xxxx))))))) | 3.689129 | 3.256557 | 1.784041 | 1.351469 | -0.430783 |
null | Melting point difference | GCGGAAUAAUCGGCCGCCACUAUGAGACAGGAAACUGUCACAUGAGGAUCACCCAUGUAUCCUCAUAGGACCGGGAUUAAAACGC | 3.93 | null | 189 | Trp | ON | 76.28 | 19.42 | null | null | 6.72 | .......................................(((((x((xxxx)))))))........................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((..................(((((x((xxxx)))))))........))xxx)))........... | 4.334411 | 2.966303 | 2.429323 | 1.061215 | 1.368639 |
null | Ex_TrypA - 3H | ACUACAAAGUAGUAUAUACGAAAGUAUAGACGAGGACCGGUACGGCCGCCACUCGGUACCGGAAACACAUGAGGAUCACCCAUGU | 0.86 | null | 170 | Trp | OFF | 17.59 | 20.57 | null | null | 6.72 | ..................................................................(((((x((xxxx))))))) | ................................((xxx(((.....)))xxx))................................ | ................................((xxx(((.....)))xxx)).............(((((x((xxxx))))))) | 3.023834 | 2.867331 | 1.118746 | 0.962242 | -0.150823 |
null | Tryp B Ex t1 | CUGCUACAUACGGCCGCCACUUUAAACAUGAGGAUCACCCAUGUACGGAAGGGUGGUAAAUGUUAAAGGACCGGGUAUGUAGCAA | 0.26 | null | 97 | Trp | OFF | 45.13 | 176.08 | null | null | 6.72 | .........................(((((x((xxxx)))))))......................................... | .............(((xxx((.............................................))xxx)))........... | .............(((xxx((....(((((x((xxxx)))))))......................))xxx)))........... | 5.170938 | 3.809547 | 3.26585 | 1.904459 | -1.347074 |