prognosis/cardio-docs-qa · Datasets at Hugging Face

What did the US Preventive Services Task Force use to detect multifactorial dys-lipidemia?

Lipid screening

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What is the name of the scientific statement from the American Heart Association?

The agenda for familial hypercholesterolemia

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What is the name of the scientific statement released by the American Heart Association?

The agenda for familial hypercholesterolemia

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What is a lipid screening in child-hood and adolescence for?

detection of multifactorial dys-lipidemia

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What is atorvas-tatin used for in children with lupus erythematosus?

reduce atherosclerosis pro-gression

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What is Ardoin used for?

Secondary analysis of APPLE study

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What is erythematosus in children and adolescents?

systemic lupus

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Arthritis Rheum. 2012;64:285–96. S4.4.4.3-32.

2016;316:634–44

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What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?

atorvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may reduce atherosclerosis pro-gression in pubertal lupus patients with higher C reactive protein?. ### Response: atorvastatin.

What is the phenotype of ath-erosclerotic cardiovascular disease in US adults with familial hypercholesterolemia?

Long-term risk

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What is a risk factor for non-coronary heart disease mortality and cancer in patients with treated heart disease?

familial hypercholesterolaemia

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What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?

Non-coronary heart disease mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia?. ### Response: Non-coronary heart disease mortality.

What was the name of the prospective regis-try study?

Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the prospective regis-try study?. ### Response: Non-coronary heart disease mortality and risk of fatal cancer in patients with treated heterozygous familial hypercholesterolaemia.

When was the Atherosclerosis.179:293–7?

2005

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What year was the 63rd issue of the journal 63:1935-47?

2014

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What is the name of the study that focuses on cholesterol screening?

S4.4.4.3-21

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What is lower estimated glomerularfiltration rate and higher albuminuria associated with?

all-cause and cardiovascular mortality

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What is a collaborative meta-analysis of kidney diseasepopulation cohorts?

Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a collaborative meta-analysis of kidney diseasepopulation cohorts?. ### Response: Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease.

Kidney Int 2011; 79: 1331–1340.17

16. Astor BC, Matsushita K, Gansevoort RT et al. Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease. A collaborative meta-analysis of kidney diseasepopulation cohorts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Kidney Int 2011; 79: 1331–1340.17. ### Response: 16. Astor BC, Matsushita K, Gansevoort RT et al. Lower estimated glomerularﬁltration rate and higher albuminuria are associated with mortality andend-stage renal disease. A collaborative meta-analysis of kidney diseasepopulation cohorts.

What are lower estimated GFR and higher albuminuria associated with?

adverse kidney outcomes

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What is the association between estimated glomerular filtration rate and albumineuria?

all-cause and cardiovas-cular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association between estimated glomerular filtration rate and albumineuria?. ### Response: all-cause and cardiovas-cular mortality.

A collaborative meta-analysis of general and high-risk population cohorts.

Kidney Int

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What is the association of estimatedglomerular filtration rate and albuminuria with all-cause and cardiovas-cular mortality in general population cohorts?

a collaborative meta-analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the association of estimatedglomerular filtration rate and albuminuria with all-cause and cardiovas-cular mortality in general population cohorts?. ### Response: a collaborative meta-analysis.

What is a collaborative meta-analysis?

kidney diseasepopulation cohorts

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What is albuminuria associated with?

all-cause and cardiovas-cular mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is albuminuria associated with?. ### Response: all-cause and cardiovas-cular mortality.

What is a collaborative meta-analysis ofhigh-risk population cohorts?

Kidney Int

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How many years ago was Kidney Int 79: 1341– 1352.20?

2011

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What is the age-specific relevance of usualblood pressure to vascular mortality?

a meta-analysis of individual datafor one million adults in 61 prospective studies

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How many prospective studies were conducted in 2002?

61

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What is the effect of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease?

mortality reduction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of stopping inhibitors of the renin-angiotensin system in patients with advanced chronic kidney disease?. ### Response: mortality reduction.

When did Ahmed AK, Kamath NS, El Kossi M et al. study the impact of stopping what?

inhibitor

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What is chronic kidney disease associated with?

coronary heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is chronic kidney disease associated with?. ### Response: coronary heart disease.

What is a reductaseinhibitor used for?

mortality reduction in hemodialysispatients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a reductaseinhibitor used for?. ### Response: mortality reduction in hemodialysispatients.

What is HMG-coenzyme a reductaseinhibitor use associated with?

mortality reduction in hemodialysispatients

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What is associated with mortality reduction in hemodialysispatients?

HMG-coenzyme a reductaseinhibitor use

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Where did Fellstrom BC, Jardine AG, Schmieder RE et al. Rosuvastatin andcardiovascular events in patients undergo?

hemodialysis

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When did N Engl JMed 2009: 360: 1395-1407.27?

2009

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What is the name of the disease that causes diabetes mellitus?

hemodialysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes diabetes mellitus?. ### Response: hemodialysis.

What are the names of the patients who are undergoing hemodialysis?

Wanner C, Krane V, Marz W et al. A t o r v a s t a t i ni np a t i e n t sw i t ht y p e2diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the patients who are undergoing hemodialysis?. ### Response: Wanner C, Krane V, Marz W et al. A t o r v a s t a t i ni np a t i e n t sw i t ht y p e2diabetes mellitus.

When was the NE n g lJM published?

2005

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What is the name of the study that found that traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease?

theatherosclerosis risk

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What are the results of the atherosclerosis risk in communities study?

Traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the results of the atherosclerosis risk in communities study?. ### Response: Traditional and nontraditional risk factorspredict coronary heart disease in chronic kidney disease.

What is the systolic blood pressure and death risk in hemodialysis patients?

epidemiology

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the systolic blood pressure and death risk in hemodialysis patients?. ### Response: epidemiology.

What are the clinical practice guidelines and recommendations for diabetes and chronic kidney disease?

KDOQI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the clinical practice guidelines and recommendations for diabetes and chronic kidney disease?. ### Response: KDOQI.

What may be a reasonable guideline in some circumstances?

Mission: Lifeline algorithm

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What will be needed to account for local and regional factors?

Customization of the guideline

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What is recommended for operationalized bypass algorithms?

Rapid, protected, collaborative, regional quality review

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Where is Table III in online Data Supplement 1?

http://ahajournals.org

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What is the name of the online data supplement?

Data Supplement 1

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When was the data supplement 1 downloaded?

April 28, 2023

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What language were systematic reviews limited to?

English

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What tool did we use to assess the quality of systematic reviews?

Assessment of Multiple Systematic Reviews

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool did we use to assess the quality of systematic reviews?. ### Response: Assessment of Multiple Systematic Reviews.

What tool was used to assess multiple systematic reviews?

Assessment of Multiple Systematic Reviews tool

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What did we use in the absence of a satisfactory systematic review?

meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we use in the absence of a satisfactory systematic review?. ### Response: meta-analyses.

How did we synthesize the evidence?

using the primarystudies identi ﬁed in AT9 and in the updated search

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did we synthesize the evidence?. ### Response: using the primarystudies identi ﬁed in AT9 and in the updated search.

What were the criteria for selecting the evidence based on the Population,Intervention, Comparator, Outcome elements of the standardizedquestions?

Study Selection, Data Abstraction, and Data Analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were the criteria for selecting the evidence based on the Population,Intervention, Comparator, Outcome elements of the standardizedquestions?. ### Response: Study Selection, Data Abstraction, and Data Analysis.

What did we follow for title and abstract screening, full textscreening, data abstraction, and risk of bias assessment?

standardprocesses

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What were the characteristics of the study design, participants,intervention, and outcomes?

control

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What tool did we use to assess risk of bias in randomized trials?

Cochrane Risk of Bias Tool

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What tool did we use to assess risk of bias in randomized trials?. ### Response: Cochrane Risk of Bias Tool.

What did we do when existing systematic reviews were not available?

we performed meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we do when existing systematic reviews were not available?. ### Response: we performed meta-analyses.

How did we assess statistical heterogeneity?

using the I2statistic

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What model did we use when pooling data from two trials?

I2statistic

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What software did we use to perform the meta-analyses and construct forest plots?

Review Manager

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How did we calculate absolute effects?

by applying pooled relative risks tobaseline risks

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What did we apply pooled relative risks to?

tobaseline risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did we apply pooled relative risks to?. ### Response: tobaseline risks.

What is the best way to estimate baseline risks?

valid prognostic observationaldata or, in the absence of the latter, from control group risks

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the best way to estimate baseline risks?. ### Response: valid prognostic observationaldata or, in the absence of the latter, from control group risks.

What was not available when we used risk estimates from control groups of RCTs?

credible data from prognostic observational studies

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How did we assess the quality of evidencebased on the data?

study design

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What is another term for the extent to which our con fidencein the effect estimate is adequate to support a recommendation?

quality of evidence

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How is quality of evidence categorized?

highest quality and up to date

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How is quality of evidence categorized?. ### Response: highest quality and up to date.

What is the rating of the quality of evidence based on?

highest quality and up to date

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What is the effect of transmembrane and C-loop loca-tion on severity of phenotype during exercise testing in type 1 long-QT syndrome?

impact

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of transmembrane and C-loop loca-tion on severity of phenotype during exercise testing in type 1 long-QT syndrome?. ### Response: impact.

What is a cardioselective beta-blocker for pediatric patients with prolonged QT syndrome called?

S7.9.1.1-27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a cardioselective beta-blocker for pediatric patients with prolonged QT syndrome called?. ### Response: S7.9.1.1-27.

What is prolonged QT syndrome?

Use of a cardioselective beta-blocker

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is prolonged QT syndrome?. ### Response: Use of a cardioselective beta-blocker.

What is a simple exercise-based algorithm for?

prediction of genetic testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a simple exercise-based algorithm for?. ### Response: prediction of genetic testing.

What is a low incidence of cardiac events with beta-blocking therapy in children with long QT syn-drome?

S7.9.1.1-29

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When did Eur Heart J. 2004:25:1405-11?

2004

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What is the response of the QT interval to the brief tachycardia provoked by standing?

a bed-side test for diagnosing long QT syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the response of the QT interval to the brief tachycardia provoked by standing?. ### Response: a bed-side test for diagnosing long QT syndrome.

What is the QT interval to the brief tachycardia provoked by standing?

a bed-side test for diagnosing long QT syndrome

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What is a bed-side test for diagnosing long QT syndrome?

The response of the QT interval to the brief tachycardia provoked by standing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a bed-side test for diagnosing long QT syndrome?. ### Response: The response of the QT interval to the brief tachycardia provoked by standing.

When was the J Am Coll Cardiol 55:1955-61 published?

2010

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What is risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals?

Goldenberg I, Horr S, Moss AJ, et al. Risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals?. ### Response: Goldenberg I, Horr S, Moss AJ, et al. Risk.

What is the name of the study that examined the risk of life-changing cardiac events among patients treated with beta-blockers?

Low incidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that examined the risk of life-changing cardiac events among patients treated with beta-blockers?. ### Response: Low incidence.

What is normalization of acquired QT prolongation in humans by intravenous potassium?

Choy AM, Lang CC, Chomsky DM, et al. Normalization of acquired QT prolongation in humans by intravenous potassium. Circulation. 1997;96:2149–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is normalization of acquired QT prolongation in humans by intravenous potassium?. ### Response: Choy AM, Lang CC, Chomsky DM, et al. Normalization of acquired QT prolongation in humans by intravenous potassium. Circulation. 1997;96:2149–.

What is the name of the drug-induced long QT syn-drome?

Darbar D

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug-induced long QT syn-drome?. ### Response: Darbar D.

When did Pharmacol Rev. 2010;62:760–81?

Drug-induced long QT syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Pharmacol Rev. 2010;62:760–81?. ### Response: Drug-induced long QT syn-drome.

What is Long-QT syndrome and therapy for?

attention deficit/hyperactivity disorder

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Long-QT syndrome and therapy for?. ### Response: attention deficit/hyperactivity disorder.

What is the J Cardiovasc Electrophysiol. 2015;26:1039–44?

S7.9.1.1-35

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Who is Priori SG, Schwartz PJ, Napolitano C, et al.?

Priori SG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is Priori SG, Schwartz PJ, Napolitano C, et al.?. ### Response: Priori SG.

What is the name of the multicenter study that examined the clinical aspects of type 3 long-QT syndrome?

international

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicenter study that examined the clinical aspects of type 3 long-QT syndrome?. ### Response: international.

What does Schwartz PJ, Spazzolini C, Crotti L say all LQT3 patients need?

an ICD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Schwartz PJ, Spazzolini C, Crotti L say all LQT3 patients need?. ### Response: an ICD.

What is the long QT syndrome in children?

Low incidence of cardiac events with beta-blocking therapy in children with long QT syn-drome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the long QT syndrome in children?. ### Response: Low incidence of cardiac events with beta-blocking therapy in children with long QT syn-drome.

How many patients were enrolled in the study?

287

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What are AEDs called in Europe?

automated external defibrillators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are AEDs called in Europe?. ### Response: automated external defibrillators.

When was the Eur Heart J 25:437-45?

2004

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What is the name of the European study that investigated the use of bisoprolol in long-QT1 and long- QT2 syndrome?

ESC-ERC

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the European study that investigated the use of bisoprolol in long-QT1 and long- QT2 syndrome?. ### Response: ESC-ERC.

What are the names of the two studies that examined the effects of Bisoprollol?

long-QT1 and long-QT2 syndrome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the two studies that examined the effects of Bisoprollol?. ### Response: long-QT1 and long-QT2 syndrome.

How many beta-blockers are equal in the management of long QT syndrome types?

Not all

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many beta-blockers are equal in the management of long QT syndrome types?. ### Response: Not all.

What are equal in the management of long QT syndrome types 1 and 2?

beta-blockers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are equal in the management of long QT syndrome types 1 and 2?. ### Response: beta-blockers.

What is higher recurrence of events under metoprolol?

long QT syndrome types 1 and 2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is higher recurrence of events under metoprolol?. ### Response: long QT syndrome types 1 and 2.