prognosis/cardio-docs-qa · Datasets at Hugging Face

What is the British Cardiovascular Society's recommendation for the Treatment of Hypertension in Stage A HF?

Asymptomatic p atients at risk for HFrecommendation Cor LoEreferenced Guideline references

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the British Cardiovascular Society's recommendation for the Treatment of Hypertension in Stage A HF?. ### Response: Asymptomatic p atients at risk for HFrecommendation Cor LoEreferenced Guideline references.

What should be controlled in accordance with contemporary guidelines?

Hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be controlled in accordance with contemporary guidelines?. ### Response: Hypertension.

What indicates Class of Recommendation?

I A 7–914, 21–28, 30, 31COR

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates Class of Recommendation?. ### Response: I A 7–914, 21–28, 30, 31COR.

What indicates LOE?

Level of Evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates LOE?. ### Response: Level of Evidence.

What should be considered in the evaluation of patients with HF symptoms?

Prosthesis–patient mismatch and functional stenosis of a repaired native valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be considered in the evaluation of patients with HF symptoms?. ### Response: Prosthesis–patient mismatch and functional stenosis of a repaired native valve.

What type of assessment begins with trans-thoracic assessment?

Repeat noninvasive assessment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of assessment begins with trans-thoracic assessment?. ### Response: Repeat noninvasive assessment.

What is the preferred approach for initial assessment of suspected prosthetic valve dysfunction?

TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the preferred approach for initial assessment of suspected prosthetic valve dysfunction?. ### Response: TTE.

What does TTE allow for?

measurement of transvalvular velocity, gradient, and valve area

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does TTE allow for?. ### Response: measurement of transvalvular velocity, gradient, and valve area.

What is the initial assessment of suspected prosthetic valve dysfunction?

TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the initial assessment of suspected prosthetic valve dysfunction?. ### Response: TTE.

What allows quantita-tion of LV volumes and LVEF?

TTE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What allows quantita-tion of LV volumes and LVEF?. ### Response: TTE.

What obscures the LA side of a prosthetic mitral valve?

acoustic shadowing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What obscures the LA side of a prosthetic mitral valve?. ### Response: acoustic shadowing.

What results in reduced sensi-tivity for detection of prosthetic MR, pannus, or vegetation?

the LA side of a prosthetic mitral valve is obscured by acoustic shadowing from the TTE approach

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What results in reduced sensi-tivity for detection of prosthetic MR, pannus, or vegetation?. ### Response: the LA side of a prosthetic mitral valve is obscured by acoustic shadowing from the TTE approach.

TEE provides superior imaging of what side of the prosthesis?

LA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: TEE provides superior imaging of what side of the prosthesis?. ### Response: LA.

What is accurate for diagnosis of prosthetic mitral valve dysfunction?

TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is accurate for diagnosis of prosthetic mitral valve dysfunction?. ### Response: TEE.

What is needed for patients with prosthetic aortic valves in which the posterior aspect of the valve is shadowed on the TTE approach?

TTE and TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed for patients with prosthetic aortic valves in which the posterior aspect of the valve is shadowed on the TTE approach?. ### Response: TTE and TEE.

On which approach is the anterior aspect of the valve shadowed?

TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On which approach is the anterior aspect of the valve shadowed?. ### Response: TEE.

Which approach has superior sensitivity for the detection of vegetations and abscess formation in patients with suspected prosthetic valve endocarditis?

TEE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which approach has superior sensitivity for the detection of vegetations and abscess formation in patients with suspected prosthetic valve endocarditis?. ### Response: TEE.

What can help detect mechanical valve obstruction?

fluoroscopy or CT imaging

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can help detect mechanical valve obstruction?. ### Response: fluoroscopy or CT imaging.

What can CT imaging help detect?

reduced motion caused by pannus ingrowth or thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can CT imaging help detect?. ### Response: reduced motion caused by pannus ingrowth or thrombus.

How much of patients with a surgical aortic valve bioprosthesis develop evidence of over the 10 years after surgery?

30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of patients with a surgical aortic valve bioprosthesis develop evidence of over the 10 years after surgery?. ### Response: 30%.

How long does it take for a patient to develop evidence of valve dysfunction?

10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long does it take for a patient to develop evidence of valve dysfunction?. ### Response: 10 years.

What is an increase in mean gradient of 10 mm Hg or a worsening of transprosthetic regurgitation from mild to moderate or from moderate to severe?

≥

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increase in mean gradient of 10 mm Hg or a worsening of transprosthetic regurgitation from mild to moderate or from moderate to severe?. ### Response: ≥.

How long after surgery does clinically important structural valve deterioration increase?

more than 10 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after surgery does clinically important structural valve deterioration increase?. ### Response: more than 10 years.

What is the risk factor associated with accelerated (5 years) valve deteriorion?

young age (<60 years) at implantation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk factor associated with accelerated (5 years) valve deteriorion?. ### Response: young age (<60 years) at implantation.

How old is the patient at implantation, smoking, and chronic kidney disease?

(<60 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How old is the patient at implantation, smoking, and chronic kidney disease?. ### Response: (<60 years.

What is the name of the disease that causes diabetes mellitus?

diabe-tes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the disease that causes diabetes mellitus?. ### Response: diabe-tes mellitus.

How many patients are at risk for TTE?

up to 13%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many patients are at risk for TTE?. ### Response: up to 13%.

What may be considered for at-risk patients on an individual basis?

The selec-tive adoption of an earlier, annual TTE screening program

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be considered for at-risk patients on an individual basis?. ### Response: The selec-tive adoption of an earlier, annual TTE screening program.

What was the date of 1402 Hypertension?

June 2015

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the date of 1402 Hypertension?. ### Response: June 2015.

What is Valsartan in Acute Myocardial Infarction Trial Investigators?

captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Valsartan in Acute Myocardial Infarction Trial Investigators?. ### Response: captopril.

What drug is used in acute myocardial infarction?

Valsartan

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What drug is used in acute myocardial infarction?. ### Response: Valsartan.

What is another name for Valsartan?

captopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Valsartan?. ### Response: captopril.

When was the N Engl J Med 349:1893-1906?

2003

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the N Engl J Med 349:1893-1906?. ### Response: 2003.

Who is the ACCOMPLISH Trial Investigator?

Jamerson K, Weber MA, Bakris GL, Dahlof B, Pitt B, Shi V , Hester A, Gupte J, Gatlin M, Velazequez EJ

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ACCOMPLISH Trial Investigator?. ### Response: Jamerson K, Weber MA, Bakris GL, Dahlof B, Pitt B, Shi V , Hester A, Gupte J, Gatlin M, Velazequez EJ.

What does Benazepril plus amlodipine or hydrochlorothiazide do for hypertension in high-risk patients?

Major outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Benazepril plus amlodipine or hydrochlorothiazide do for hypertension in high-risk patients?. ### Response: Major outcomes.

When did N Engl J Med. 2008:359:2417-2428?

93

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did N Engl J Med. 2008:359:2417-2428?. ### Response: 93.

What is the average diastolic blood pressure?

90 through 114 mm Hg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the average diastolic blood pressure?. ### Response: 90 through 114 mm Hg.

When was the JAMA published?

2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the JAMA published?. ### Response: 2002.

What was the main result of the MRC trial?

treatment of mild hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main result of the MRC trial?. ### Response: treatment of mild hypertension.

What is the name of the Systolic Hypertension in the Elderly Program?

SHEP): SHEP Cooperative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Systolic Hypertension in the Elderly Program?. ### Response: SHEP): SHEP Cooperative Research Group.

When was SHEP Cooperative Research Group founded?

1991

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was SHEP Cooperative Research Group founded?. ### Response: 1991.

What was the main outcome of the ALLHAT Collaborative Research Group?

high-risk hyperten-sive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the main outcome of the ALLHAT Collaborative Research Group?. ### Response: high-risk hyperten-sive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic.

What is the name of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.

What are the major outcomes in high-risk hyperten-sive patients randomized to?

angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the major outcomes in high-risk hyperten-sive patients randomized to?. ### Response: angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic.

What is the name of the study that investigated the adverse prognostic signifi-cance of new diabetes in treated hypertensive subjects?

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that investigated the adverse prognostic signifi-cance of new diabetes in treated hypertensive subjects?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

What was the title of this study?

ACCOMPLISH Trial Investigators

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the title of this study?. ### Response: ACCOMPLISH Trial Investigators.

In what year did Hypertension 43:963-969?

2004

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Hypertension 43:963-969?. ### Response: 2004.

What is the name of the study that evaluated antihypertensive and lipid-lowering treatment to prevent heart attack?

ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that evaluated antihypertensive and lipid-lowering treatment to prevent heart attack?. ### Response: ALLHAT Collaborative Research Group.

What is lisinopril used for in nondiabetic individuals?

hypertension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is lisinopril used for in nondiabetic individuals?. ### Response: hypertension.

What is the name of the trial that evaluated lisinopril as an initial treatment for hypertension?

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the trial that evaluated lisinopril as an initial treatment for hypertension?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

What is ALHAT?

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is ALHAT?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

Diabetes Care. 2008;31:353–360.

98

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Diabetes Care. 2008;31:353–360.. ### Response: 98.

What is the name of the research group that studies mortality and morbidity during and after the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that studies mortality and morbidity during and after the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT Collaborative Research Group.

What is Lipid-Lowering Treatment to Prevent Heart Attack?

Antihypertensive

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Lipid-Lowering Treatment to Prevent Heart Attack?. ### Response: Antihypertensive.

What is Greenwich's J Clin Hypertens?

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Greenwich's J Clin Hypertens?. ### Response: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

What were people with heart failure often unaware of?

the term ‘heart failure’

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were people with heart failure often unaware of?. ### Response: the term ‘heart failure’.

What did many describe that the term was not mentioned initially but introduced later by specialists?

heart failure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did many describe that the term was not mentioned initially but introduced later by specialists?. ### Response: heart failure.

What was the subfinding based on?

si x studies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the subfinding based on?. ### Response: si x studies.

What did shock and confusion cause?

patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did shock and confusion cause?. ### Response: patients.

S4.4-42. Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality: a systematic review and network meta-analysis. 2017;2:775–81.

288:2421–31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: S4.4-42. Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality: a systematic review and network meta-analysis. 2017;2:775–81.. ### Response: 288:2421–31.

Ruggenenti P, Perna A, Loriga G, and Ruggenti P. What is blood-pressure control for in patients with non-diabetic chronic renal disease?

renoprotection

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Ruggenenti P, Perna A, Loriga G, and Ruggenti P. What is blood-pressure control for in patients with non-diabetic chronic renal disease?. ### Response: renoprotection.

What is the name of the multicentre, randomised controlled trial in non-diabetic chronic renal dis-ease?

REIN-2

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the multicentre, randomised controlled trial in non-diabetic chronic renal dis-ease?. ### Response: REIN-2.

What does REIN-2 stand for?

Blood-pressure control for renoprotection in patients with non-diabetic chronic renal dis-ease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does REIN-2 stand for?. ### Response: Blood-pressure control for renoprotection in patients with non-diabetic chronic renal dis-ease.

When did the AASK trial take place?

2002

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did the AASK trial take place?. ### Response: 2002.

What is hypertensive kidney disease?

AASK trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is hypertensive kidney disease?. ### Response: AASK trial.

When was the AASK trial published?

2002;288:2421–31.Downloaded from http://ahajournals.org by on May 1, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the AASK trial published?. ### Response: 2002;288:2421–31.Downloaded from http://ahajournals.org by on May 1, 2023.

What was the name of the trial?

AASK trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the trial?. ### Response: AASK trial.

What should anticoagulant and antiplatelet therapy be ad-justed when necessary for CKD to decrease the risk of bleeding in patients with NSTE-ACS?

weight-based where appropriate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should anticoagulant and antiplatelet therapy be ad-justed when necessary for CKD to decrease the risk of bleeding in patients with NSTE-ACS?. ### Response: weight-based where appropriate.

What is a strategy of routine blood transfusion in hemody-namically stable patients?

not recommend-ed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a strategy of routine blood transfusion in hemody-namically stable patients?. ### Response: not recommend-ed.

What is not recommended in hemody-namically stable patients with NSTE-ACS?

routine blood transfusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in hemody-namically stable patients with NSTE-ACS?. ### Response: routine blood transfusion.

What is associated with an increased risk for Holter monitor-detected recurrent ischemia and MACE?

Anemia in patients with ACS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an increased risk for Holter monitor-detected recurrent ischemia and MACE?. ### Response: Anemia in patients with ACS.

What is the risk of anemia in patients with NSTE-ACS with hemoglobin levels 11 g/dL?

adverse outcome

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of anemia in patients with NSTE-ACS with hemoglobin levels 11 g/dL?. ### Response: adverse outcome.

What are the potentially detrimental effects of severe anemia?

decreased myocardial oxygen delivery and increased MVO2 related to maintenance of a higher cardiac output

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the potentially detrimental effects of severe anemia?. ### Response: decreased myocardial oxygen delivery and increased MVO2 related to maintenance of a higher cardiac output.

What are the two main causes of severe anemia?

decreased myocardial oxygen delivery and increased MVO2 related to maintenance of a higher cardiac output

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two main causes of severe anemia?. ### Response: decreased myocardial oxygen delivery and increased MVO2 related to maintenance of a higher cardiac output.

What are patients with anemia less likely to be treated with?

aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are patients with anemia less likely to be treated with?. ### Response: aspirin.

Patients with ACS and anemia are likely to have more bleeding complica-tions with what?

PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with ACS and anemia are likely to have more bleeding complica-tions with what?. ### Response: PCI.

What has been correlated with increased short-term risk of MACE outcomes?

bleeding complica-tions with PCI

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been correlated with increased short-term risk of MACE outcomes?. ### Response: bleeding complica-tions with PCI.

What study suggests that the risk of mortality associated with bleeding is at least as great as that associated with procedure-related or spontaneous MI?

ACUITY

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What study suggests that the risk of mortality associated with bleeding is at least as great as that associated with procedure-related or spontaneous MI?. ### Response: ACUITY.

What is a coprimary endpoint in many trials?

Major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a coprimary endpoint in many trials?. ### Response: Major bleeding.

What is considered when assessing the "net clinical ben-efit" of a new drug?

Major bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered when assessing the "net clinical ben-efit" of a new drug?. ### Response: Major bleeding.

A "universal definition of bleeding" has been proposed to assist clinicians what?

547

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: A "universal definition of bleeding" has been proposed to assist clinicians what?. ### Response: 547.

How does the incidence of major bleeding in patients with ACS vary?

widely

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does the incidence of major bleeding in patients with ACS vary?. ### Response: widely.

What is one of the factors that contributes to an increased bleeding risk in ACS patients?

older age

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is one of the factors that contributes to an increased bleeding risk in ACS patients?. ### Response: older age.

What is the risk of CKD?

bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of CKD?. ### Response: bleeding.

What are non-weight-based dosing of anticoagu-lants and antiplatelet medications associated with?

an increased risk of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are non-weight-based dosing of anticoagu-lants and antiplatelet medications associated with?. ### Response: an increased risk of bleeding.

What are adjusted for CKD associated with an increased risk of?

bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are adjusted for CKD associated with an increased risk of?. ### Response: bleeding.

Bleeding is related to adverse out-comes because it may be a marker of underlying disease, such as occult malignancy?

522,697,698

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Bleeding is related to adverse out-comes because it may be a marker of underlying disease, such as occult malignancy?. ### Response: 522,697,698.

What may prompt transfusion which itself may have adverse effects?

Bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may prompt transfusion which itself may have adverse effects?. ### Response: Bleeding.

What can transfusion cause?

hypotension

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can transfusion cause?. ### Response: hypotension.

What can be fatal if intracranial?

bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be fatal if intracranial?. ### Response: bleeding.

Proton pump inhibitors decrease the risk of upper GI bleeding in patients treated with what?

DAPT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Proton pump inhibitors decrease the risk of upper GI bleeding in patients treated with what?. ### Response: DAPT.

What is an option in patients at increased risk of GI bleeding?

Proton pump inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an option in patients at increased risk of GI bleeding?. ### Response: Proton pump inhibitors.

What includes a focused his-and-her evaluation?

the risk of bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What includes a focused his-and-her evaluation?. ### Response: the risk of bleeding.

What are crucial prerequisites to optimize therapy for adults with Eisenmenger syndrome?

hypertension by means of advanced imaging and cardiac catheterization

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are crucial prerequisites to optimize therapy for adults with Eisenmenger syndrome?. ### Response: hypertension by means of advanced imaging and cardiac catheterization.

In adults with ASD or VSD in WHO functional class III or IV, RCTs demonstrate improved what?

6-minute walk distance, hemody-namics, and subjective functional ability

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In adults with ASD or VSD in WHO functional class III or IV, RCTs demonstrate improved what?. ### Response: 6-minute walk distance, hemody-namics, and subjective functional ability.

How long did oral bosentan last?

months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did oral bosentan last?. ### Response: months.

What has shown long-term benefit?

open-label extension of this initial RCTS4.4.6.2-1 and in single-center registry cohorts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has shown long-term benefit?. ### Response: open-label extension of this initial RCTS4.4.6.2-1 and in single-center registry cohorts.

How long has there been a class effect?

months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long has there been a class effect?. ### Response: months.

What are endothelin receptor antagonists studied for?

class effect

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are endothelin receptor antagonists studied for?. ### Response: class effect.

What is the name of the randomized crossover trial that enrolled adults with Eisenmenger syndrome or idiopathic PAH?

combination PAH therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the randomized crossover trial that enrolled adults with Eisenmenger syndrome or idiopathic PAH?. ### Response: combination PAH therapy.