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marcovarrone
/
scvi-dlpfc-full-visium

scvi-tools
biology
genomics
single-cell
model_cls_name:SCVI
scvi_version:0.20.0
anndata_version:0.8.0
modality:rna
annotated:False
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scvi-dlpfc-full-visium
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---
license: cc-by-4.0
library_name: scvi-tools
tags:
- biology
- genomics
- single-cell
- model_cls_name:SCVI
- scvi_version:0.20.0
- anndata_version:0.8.0
- modality:rna
- annotated:False
---

# Description

scVI model trained on the full DLPFC Visium data (including the pilot samples). 

# Model properties

Many model properties are in the model tags. Some more are listed below.

**model_init_params**:
```json
{
    "n_hidden": 128,
    "n_latent": 5,
    "n_layers": 1,
    "dropout_rate": 0.1,
    "dispersion": "gene",
    "gene_likelihood": "zinb",
    "latent_distribution": "normal"
}
```

**model_setup_anndata_args**:
```json
{
    "layer": "counts",
    "batch_key": "patient",
    "labels_key": null,
    "size_factor_key": null,
    "categorical_covariate_keys": [
        "sample",
        "study"
    ],
    "continuous_covariate_keys": null
}
```

**model_summary_stats**:
|     Summary Stat Key     | Value  |
|--------------------------|--------|
|         n_batch          |   13   |
|         n_cells          | 166443 |
| n_extra_categorical_covs |   2    |
| n_extra_continuous_covs  |   0    |
|         n_labels         |   1    |
|          n_vars          |  5000  |

**model_data_registry**:
|      Registry Key      |            scvi-tools Location             |
|------------------------|--------------------------------------------|
|           X            |           adata.layers['counts']           |
|         batch          |          adata.obs['_scvi_batch']          |
| extra_categorical_covs | adata.obsm['_scvi_extra_categorical_covs'] |
|         labels         |         adata.obs['_scvi_labels']          |

**model_parent_module**: scvi.model

**data_is_minified**: False

# Training data

This is an optional link to where the training data is stored if it is too large
to host on the huggingface Model hub.

<!-- If your model is not uploaded with any data (e.g., minified data) on the Model Hub, then make
sure to provide this field if you want users to be able to access your training data. See the scvi-tools
documentation for details. -->

Training data url: N/A

# Training code

This is an optional link to the code used to train the model.

Training code url: N/A

# References

1. Maynard, Kristen R., et al. "Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex." Nature neuroscience 24.3 (2021): 425-436.
2. Huuki-Myers, Louise A., et al. "Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex." BioRxiv (2023): 2023-02.