popV/tabula_muris_All

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	3687	0.86	0.90	0.86	0.86	0.00	0.89	0.75	0.78	0.91
mesenchymal stem cell	1678	0.87	0.88	0.89	0.68	0.00	0.69	0.91	0.87	0.93
basal cell of epidermis	1499	0.85	0.88	0.81	0.84	0.00	0.84	0.86	0.82	0.90
granulocyte	1556	0.81	0.86	0.79	0.74	0.00	0.78	0.74	0.80	0.88
endothelial cell	1478	0.88	0.88	0.82	0.74	0.00	0.79	0.90	0.85	0.93
microglial cell	1293	0.99	0.99	0.96	0.99	0.00	0.98	0.99	0.99	1.00
T cell	1244	0.75	0.80	0.63	0.58	0.00	0.67	0.62	0.73	0.82
keratinocyte	1254	0.85	0.89	0.81	0.80	0.00	0.86	0.88	0.85	0.91
macrophage	971	0.47	0.68	0.59	0.51	0.00	0.48	0.53	0.56	0.71
classical monocyte	765	0.75	0.60	0.61	0.56	0.00	0.78	0.79	0.83	0.88
granulocytopoietic cell	807	0.67	0.77	0.62	0.51	0.00	0.46	0.68	0.75	0.80
bladder urothelial cell	680	0.98	0.99	0.96	0.85	0.00	0.96	1.00	0.98	0.99
mesenchymal stem cell of adipose tissue	650	0.74	0.84	0.72	0.51	0.00	0.54	0.90	0.80	0.88
fibroblast of cardiac tissue	613	0.96	0.94	0.80	0.46	0.00	0.66	0.95	0.91	0.96
endothelial cell of coronary artery	624	0.81	0.86	0.63	0.58	0.00	0.77	0.89	0.84	0.91
skeletal muscle satellite cell	465	0.98	0.98	0.95	0.97	0.00	0.96	0.97	0.97	0.98
proerythroblast	435	0.52	0.56	0.51	0.22	0.00	0.26	0.51	0.60	0.64
kidney proximal convoluted tubule epithelial cell	445	0.84	0.87	0.34	0.82	0.00	0.75	0.87	0.88	0.89
bronchial smooth muscle cell	454	0.96	0.96	0.84	0.91	0.00	0.92	0.97	0.94	0.96
myeloid cell	413	0.44	0.60	0.41	0.42	0.00	0.25	0.70	0.68	0.69
hepatocyte	377	0.98	0.98	0.98	0.97	0.00	0.98	0.99	0.98	0.99
type B pancreatic cell	428	0.97	0.98	0.96	0.98	0.00	0.98	0.99	0.98	0.99
bladder cell	411	0.97	0.95	0.97	0.58	0.00	0.84	0.98	0.96	0.98
promonocyte	365	0.65	0.72	0.66	0.61	0.00	0.58	0.74	0.78	0.82
DN4 thymocyte	425	0.39	0.53	0.38	0.31	0.00	0.23	0.58	0.63	0.62
basal cell	384	0.98	0.97	0.97	0.92	0.00	0.96	0.98	0.96	0.98
monocyte	350	0.60	0.57	0.48	0.31	0.00	0.37	0.73	0.76	0.84
enterocyte of epithelium of large intestine	374	0.92	0.93	0.84	0.92	0.00	0.92	0.94	0.92	0.95
thymocyte	370	0.82	0.74	0.59	0.82	0.00	0.87	0.89	0.92	0.88
epithelial cell of proximal tubule	342	0.84	0.82	0.78	0.76	0.00	0.82	0.85	0.85	0.85
natural killer cell	352	0.84	0.82	0.68	0.68	0.00	0.74	0.74	0.80	0.85
naive B cell	341	0.46	0.22	0.40	0.36	0.00	0.48	0.49	0.56	0.58
hematopoietic stem cell	337	0.92	0.93	0.88	0.88	0.00	0.88	0.94	0.93	0.94
mature NK T cell	321	0.57	0.64	0.46	0.32	0.00	0.59	0.59	0.70	0.71
fibroblast	309	0.20	0.25	0.53	0.31	0.00	0.32	0.56	0.54	0.52
stromal cell	331	0.61	0.49	0.86	0.33	0.00	0.37	0.85	0.71	0.86
keratinocyte stem cell	321	0.95	0.95	0.84	0.87	0.00	0.93	0.96	0.91	0.96
erythroblast	291	0.60	0.69	0.66	0.56	0.00	0.54	0.66	0.71	0.76
Kupffer cell	280	0.98	0.95	0.71	0.42	0.00	0.83	0.98	0.94	0.97
megakaryocyte-erythroid progenitor cell	244	0.53	0.62	0.45	0.41	0.00	0.57	0.55	0.66	0.69
pancreatic acinar cell	235	0.95	0.95	0.93	0.97	0.00	0.98	0.99	0.99	0.98
luminal epithelial cell of mammary gland	300	0.94	0.94	0.98	0.87	0.00	0.92	0.97	0.93	0.97
professional antigen presenting cell	257	0.05	0.02	0.09	0.01	0.00	0.01	0.41	0.36	0.06
epidermal cell	219	0.84	0.85	0.75	0.84	0.00	0.84	0.86	0.86	0.90
hematopoietic precursor cell	216	0.63	0.74	0.39	0.24	0.00	0.55	0.71	0.78	0.80
oligodendrocyte	224	0.96	0.98	0.97	0.99	0.00	0.99	0.99	0.99	0.99
fibroblast of lung	216	0.98	0.96	0.94	0.90	0.00	0.95	0.98	0.94	0.99
CD8-positive, alpha-beta T cell	183	0.35	0.52	0.28	0.32	0.00	0.44	0.48	0.57	0.64
epithelial cell of large intestine	174	0.74	0.79	0.57	0.68	0.00	0.73	0.85	0.82	0.83
intestinal crypt stem cell	199	0.84	0.86	0.69	0.80	0.00	0.82	0.87	0.82	0.87
chondrocyte	179	0.60	0.61	0.78	0.68	0.00	0.64	0.85	0.85	0.69
immature T cell	181	0.72	0.03	0.12	0.61	0.00	0.79	0.82	0.88	0.77
precursor B cell	192	0.66	0.88	0.55	0.62	0.00	0.66	0.78	0.84	0.84
intermediate monocyte	167	0.34	0.12	0.36	0.24	0.00	0.63	0.53	0.58	0.64
large intestine goblet cell	163	0.79	0.85	0.79	0.76	0.00	0.81	0.91	0.86	0.88
CD4-positive, alpha-beta T cell	164	0.25	0.38	0.22	0.26	0.00	0.38	0.33	0.45	0.55
smooth muscle cell	167	0.59	0.79	0.66	0.61	0.00	0.73	0.84	0.81	0.77
leukocyte	156	0.52	0.59	0.35	0.18	0.00	0.32	0.62	0.68	0.77
plasma cell	143	0.48	0.66	0.47	0.41	0.00	0.60	0.52	0.60	0.71
lymphocyte	173	0.18	0.20	0.31	0.13	0.00	0.00	0.23	0.38	0.35
naive T cell	146	0.79	0.85	0.85	0.82	0.00	0.84	0.86	0.86	0.87
kidney loop of Henle thick ascending limb epithelial cell	141	0.92	0.91	0.66	0.79	0.00	0.42	0.89	0.92	0.94
immature B cell	147	0.71	0.76	0.57	0.69	0.00	0.58	0.52	0.71	0.82
alveolar macrophage	134	0.93	0.93	0.90	0.89	0.00	0.93	0.95	0.90	0.94
endothelial cell of hepatic sinusoid	122	0.95	0.93	0.89	0.81	0.00	0.86	0.98	0.93	0.96
lung macrophage	106	0.87	0.09	0.30	0.00	0.00	0.81	0.87	0.81	0.94
non-classical monocyte	114	0.60	0.73	0.41	0.56	0.00	0.69	0.78	0.70	0.75
endocardial cell	113	0.92	0.92	0.88	0.85	0.00	0.79	0.92	0.85	0.93
double negative thymocyte	105	0.55	0.00	0.31	0.20	0.00	0.64	0.72	0.81	0.83
late pro-B cell	92	0.80	0.82	0.37	0.54	0.00	0.59	0.68	0.80	0.90
kidney collecting duct principal cell	105	0.64	0.86	0.78	0.86	0.00	0.84	0.91	0.85	0.89
basal epithelial cell of tracheobronchial tree	87	0.89	0.77	0.83	0.49	0.00	0.57	0.93	0.86	0.93
mesenchymal cell	91	0.20	0.00	0.14	0.11	0.00	0.12	0.45	0.49	0.42
pancreatic A cell	81	0.61	0.77	0.44	0.83	0.00	0.80	0.91	0.89	0.86
adventitial cell	63	0.69	0.62	0.45	0.07	0.00	0.23	0.76	0.54	0.81
epithelial cell	52	0.38	0.07	0.46	0.38	0.00	0.27	0.51	0.49	0.62
kidney distal convoluted tubule epithelial cell	80	0.76	0.86	0.62	0.63	0.00	0.86	0.87	0.86	0.87
neutrophil	73	0.54	0.68	0.46	0.18	0.00	0.28	0.66	0.58	0.68
pancreatic ductal cell	55	0.98	0.81	0.78	0.93	0.00	0.96	0.96	0.96	0.98
myeloid dendritic cell	54	0.36	0.58	0.40	0.33	0.00	0.42	0.69	0.62	0.68
astrocyte	70	0.93	0.95	0.98	0.98	0.00	0.99	0.99	0.96	0.99
secretory cell	52	0.21	0.49	0.37	0.45	0.00	0.65	0.87	0.77	0.70
myeloid leukocyte	56	0.69	0.41	0.42	0.27	0.00	0.31	0.44	0.57	0.80
plasmatocyte	48	0.55	0.78	0.63	0.76	0.00	0.61	0.88	0.83	0.87
brain pericyte	56	0.00	0.77	0.56	0.76	0.00	0.87	0.97	0.84	0.95
neuron	48	0.59	0.62	0.66	0.65	0.00	0.72	0.90	0.81	0.87
vein endothelial cell	49	0.67	0.81	0.64	0.26	0.00	0.74	0.86	0.72	0.85
kidney collecting duct epithelial cell	49	0.00	0.63	0.20	0.56	0.00	0.39	0.78	0.85	0.91
pancreatic D cell	46	0.00	0.76	0.52	0.89	0.00	0.95	0.96	0.96	0.97
aortic endothelial cell	12	0.08	0.12	0.18	0.21	0.00	0.14	0.13	0.08	0.37
brush cell	37	0.78	0.59	0.35	0.68	0.00	0.80	0.72	0.73	0.81
erythroid progenitor cell, mammalian	48	0.57	0.00	0.18	0.05	0.00	0.26	0.79	0.65	0.49
regular atrial cardiac myocyte	35	0.00	0.58	0.44	0.44	0.00	0.37	0.52	0.66	0.77
kidney cortex artery cell	40	0.00	0.83	0.58	0.24	0.00	0.62	0.83	0.62	0.85
erythrocyte	44	0.63	0.63	0.64	0.63	0.00	0.67	0.74	0.85	0.80
mesangial cell	32	0.00	0.58	0.22	0.28	0.00	0.50	0.66	0.59	0.81
kidney loop of Henle ascending limb epithelial cell	32	0.56	0.59	0.43	0.33	0.00	0.35	0.72	0.67	0.74
cardiac muscle cell	32	0.63	0.81	0.62	0.71	0.00	0.94	1.00	0.97	0.97
mature alpha-beta T cell	37	0.00	0.27	0.28	0.38	0.00	0.52	0.39	0.44	0.56
basophil	33	0.64	0.61	0.59	0.47	0.00	0.38	0.54	0.62	0.73
cardiac valve cell	22	0.45	0.71	0.51	0.56	0.00	0.58	0.83	0.78	0.72
oligodendrocyte precursor cell	29	0.87	0.95	0.93	0.97	0.00	0.98	0.98	1.00	0.98
Schwann cell	22	0.63	0.67	0.81	0.65	0.00	0.81	0.77	0.67	0.74
pulmonary interstitial fibroblast	24	0.87	0.86	0.70	0.75	0.00	0.92	0.96	0.90	0.92
smooth muscle cell of trachea	25	0.00	0.00	0.11	0.07	0.00	0.23	0.35	0.50	0.36
granulocyte monocyte progenitor cell	28	0.60	0.71	0.56	0.69	0.00	0.47	0.85	0.77	0.85
interneuron	25	0.00	0.53	0.28	0.65	0.00	0.86	0.94	0.78	0.94
pancreatic PP cell	23	0.00	0.23	0.08	0.56	0.00	0.68	0.78	0.76	0.61
smooth muscle cell of the pulmonary artery	26	0.00	0.68	0.56	0.21	0.00	0.33	0.88	0.70	0.73
cell of skeletal muscle	16	0.94	0.94	0.78	0.97	0.00	0.94	0.91	0.94	0.94
Langerhans cell	18	0.88	0.85	0.36	0.38	0.00	0.41	0.90	0.81	0.91
brush cell of epithelium proper of large intestine	10	0.00	0.78	0.00	0.67	0.00	0.62	0.90	0.82	0.80
stem cell of epidermis	11	0.00	0.00	0.50	0.12	0.00	0.36	0.56	0.53	0.62
regulatory T cell	13	0.00	0.00	0.00	0.06	0.00	0.14	0.12	0.21	0.25
epithelial cell of thymus	16	0.00	0.00	0.17	0.36	0.00	0.06	0.52	0.25	0.30
enteroendocrine cell	8	0.67	0.60	0.33	0.59	0.00	0.67	0.89	0.78	0.74
kidney capillary endothelial cell	19	0.17	0.54	0.30	0.18	0.00	0.30	0.26	0.27	0.27
neuroepithelial stem cell	16	0.18	0.21	0.36	0.27	0.00	0.23	0.62	0.29	0.52
macrophage dendritic cell progenitor	9	0.00	0.14	0.52	0.14	0.00	0.52	0.44	0.62	0.70
DN3 thymocyte	16	0.00	0.00	0.00	0.43	0.00	0.79	0.82	0.73	0.52
regular ventricular cardiac myocyte	9	0.00	0.00	0.78	0.48	0.00	0.53	0.84	1.00	0.89
endothelial cell of lymphatic vessel	5	0.00	0.43	0.80	0.10	0.00	0.09	0.34	0.21	0.57
ciliated columnar cell of tracheobronchial tree	16	0.72	0.80	0.85	0.80	0.00	0.59	0.88	0.75	0.88
plasmacytoid dendritic cell	13	0.00	0.56	0.32	0.24	0.00	0.13	0.44	0.29	0.52
dendritic cell	10	0.00	0.25	0.22	0.32	0.00	0.16	0.54	0.30	0.48
medium spiny neuron	14	0.00	0.78	0.58	0.48	0.00	0.93	0.97	0.96	0.88
pericyte	16	0.00	0.94	0.87	0.58	0.00	0.81	1.00	0.94	1.00
neural stem cell	10	0.00	0.82	0.57	0.76	0.00	0.86	0.78	0.73	0.86
kidney proximal straight tubule epithelial cell	8	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.19	0.00
blood cell	9	0.20	0.00	0.36	0.00	0.00	0.00	0.21	0.18	0.32
immature NK T cell	8	0.00	0.22	0.36	0.00	0.00	0.24	0.41	0.35	0.50
cardiac neuron	10	0.00	0.31	0.29	0.12	0.00	0.32	0.74	0.77	0.62
mast cell	12	0.00	0.00	0.15	0.29	0.00	0.11	0.54	0.56	0.56
mucus secreting cell	8	0.00	0.62	0.88	0.50	0.00	0.48	0.78	0.89	0.94
early pro-B cell	6	0.00	0.60	0.00	0.46	0.00	0.19	0.62	0.38	0.83
pancreatic stellate cell	9	0.00	0.75	0.36	0.57	0.00	0.16	0.82	0.84	0.84
ependymal cell	5	0.00	0.75	1.00	0.67	0.00	0.50	0.77	0.77	0.77
Bergmann glial cell	4	0.00	0.40	0.57	0.67	0.00	0.67	1.00	0.89	1.00
neuroendocrine cell	7	0.00	0.00	0.00	0.00	0.00	0.00	0.20	0.14	0.00
fibrocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
hepatic stellate cell	5	0.00	0.00	0.60	0.77	0.00	0.56	0.91	0.83	1.00
club cell	7	0.14	0.25	0.10	0.15	0.00	0.13	0.14	0.13	0.14
respiratory basal cell	2	0.00	0.00	0.00	0.50	0.00	0.11	0.67	0.67	0.67
kidney interstitial fibroblast	1	0.00	0.00	0.00	0.00	0.00	0.00	0.67	1.00	0.00
lymphoid lineage restricted progenitor cell	1	0.00	0.00	1.00	0.67	0.00	0.40	0.03	1.00	1.00
lung neuroendocrine cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
kidney cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
duct epithelial cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	32653	0.86	0.89	0.88	0.93	0.00	0.95	0.75	0.79	0.94
mesenchymal stem cell	14461	0.86	0.86	0.96	0.87	0.00	0.86	0.92	0.87	0.95
basal cell of epidermis	14140	0.85	0.87	0.91	0.91	0.00	0.85	0.87	0.83	0.92
granulocyte	14006	0.80	0.84	0.90	0.91	0.00	0.87	0.74	0.81	0.91
endothelial cell	13329	0.87	0.86	0.87	0.86	0.00	0.88	0.91	0.85	0.95
microglial cell	11975	0.99	0.99	0.94	0.99	0.00	0.97	0.99	0.99	0.99
T cell	11497	0.75	0.79	0.77	0.85	0.00	0.89	0.65	0.74	0.88
keratinocyte	11101	0.85	0.88	0.91	0.91	0.00	0.88	0.89	0.86	0.92
macrophage	8653	0.48	0.64	0.80	0.76	0.00	0.76	0.57	0.61	0.80
classical monocyte	7359	0.76	0.55	0.80	0.88	0.00	0.90	0.81	0.84	0.92
granulocytopoietic cell	7275	0.66	0.78	0.84	0.85	0.00	0.82	0.69	0.80	0.89
bladder urothelial cell	5958	0.98	0.98	0.99	0.95	0.00	0.99	0.99	0.98	0.99
mesenchymal stem cell of adipose tissue	5973	0.76	0.82	0.89	0.71	0.00	0.91	0.92	0.82	0.94
fibroblast of cardiac tissue	5710	0.94	0.92	0.88	0.73	0.00	0.87	0.96	0.91	0.97
endothelial cell of coronary artery	5363	0.80	0.83	0.79	0.78	0.00	0.91	0.90	0.84	0.96
skeletal muscle satellite cell	4308	0.98	0.98	0.97	0.97	0.00	0.97	0.97	0.97	0.98
proerythroblast	4242	0.51	0.52	0.72	0.75	0.00	0.77	0.57	0.66	0.74
kidney proximal convoluted tubule epithelial cell	4015	0.83	0.83	0.91	0.89	0.00	0.90	0.90	0.89	0.92
bronchial smooth muscle cell	4002	0.95	0.96	0.81	0.93	0.00	0.93	0.97	0.95	0.97
myeloid cell	4007	0.44	0.57	0.73	0.68	0.00	0.84	0.74	0.72	0.85
hepatocyte	3698	0.99	0.98	0.99	0.99	0.00	0.99	0.99	0.99	0.99
type B pancreatic cell	3587	0.97	0.96	0.96	0.98	0.00	0.98	0.99	0.98	0.99
bladder cell	3600	0.97	0.95	0.99	0.75	0.00	0.97	0.98	0.96	0.99
promonocyte	3477	0.65	0.69	0.85	0.83	0.00	0.85	0.78	0.83	0.88
DN4 thymocyte	3331	0.34	0.45	0.60	0.69	0.00	0.88	0.61	0.66	0.80
basal cell	3342	0.98	0.97	0.98	0.94	0.00	0.96	0.98	0.97	0.99
monocyte	3324	0.61	0.53	0.74	0.76	0.00	0.88	0.77	0.81	0.90
enterocyte of epithelium of large intestine	3293	0.91	0.92	0.94	0.93	0.00	0.95	0.95	0.93	0.96
thymocyte	3147	0.80	0.75	0.86	0.92	0.00	0.91	0.91	0.93	0.96
epithelial cell of proximal tubule	3101	0.82	0.78	0.87	0.85	0.00	0.87	0.87	0.86	0.88
natural killer cell	3009	0.82	0.81	0.74	0.83	0.00	0.86	0.80	0.84	0.88
naive B cell	3016	0.44	0.19	0.81	0.66	0.00	0.79	0.52	0.56	0.84
hematopoietic stem cell	3005	0.92	0.93	0.93	0.94	0.00	0.93	0.95	0.94	0.95
mature NK T cell	2840	0.54	0.62	0.61	0.79	0.00	0.81	0.63	0.72	0.78
fibroblast	2834	0.18	0.24	0.75	0.63	0.00	0.74	0.64	0.65	0.77
stromal cell	2792	0.61	0.39	0.97	0.64	0.00	0.93	0.87	0.75	0.93
keratinocyte stem cell	2736	0.92	0.92	0.93	0.92	0.00	0.94	0.95	0.90	0.96
erythroblast	2627	0.59	0.68	0.82	0.85	0.00	0.86	0.69	0.75	0.85
Kupffer cell	2526	0.97	0.94	0.87	0.91	0.00	0.96	0.98	0.97	0.99
megakaryocyte-erythroid progenitor cell	2548	0.59	0.63	0.77	0.76	0.00	0.73	0.64	0.73	0.80
pancreatic acinar cell	2472	0.96	0.95	0.94	0.99	0.00	0.98	0.99	0.99	0.99
luminal epithelial cell of mammary gland	2371	0.92	0.91	0.98	0.93	0.00	0.97	0.97	0.95	0.98
professional antigen presenting cell	2347	0.03	0.01	0.27	0.45	0.00	0.93	0.44	0.40	0.49
epidermal cell	2008	0.87	0.87	0.90	0.90	0.00	0.88	0.88	0.87	0.92
hematopoietic precursor cell	1928	0.62	0.71	0.62	0.79	0.00	0.91	0.74	0.81	0.90
oligodendrocyte	1870	0.96	0.99	0.97	1.00	0.00	0.99	1.00	0.99	0.99
fibroblast of lung	1790	0.96	0.95	0.93	0.93	0.00	0.97	0.98	0.97	0.98
CD8-positive, alpha-beta T cell	1757	0.34	0.48	0.45	0.63	0.00	0.69	0.60	0.63	0.74
epithelial cell of large intestine	1759	0.74	0.79	0.86	0.79	0.00	0.82	0.88	0.86	0.89
intestinal crypt stem cell	1719	0.82	0.86	0.90	0.88	0.00	0.87	0.90	0.87	0.92
chondrocyte	1726	0.61	0.62	0.85	0.83	0.00	0.82	0.88	0.88	0.82
immature T cell	1603	0.66	0.00	0.82	0.91	0.00	0.92	0.89	0.89	0.96
precursor B cell	1579	0.67	0.84	0.91	0.87	0.00	0.87	0.85	0.88	0.92
intermediate monocyte	1594	0.35	0.07	0.52	0.67	0.00	0.68	0.57	0.62	0.74
large intestine goblet cell	1582	0.81	0.84	0.92	0.85	0.00	0.91	0.95	0.92	0.95
CD4-positive, alpha-beta T cell	1557	0.26	0.37	0.47	0.61	0.00	0.59	0.48	0.57	0.73
smooth muscle cell	1536	0.61	0.76	0.83	0.86	0.00	0.89	0.90	0.83	0.84
leukocyte	1502	0.52	0.48	0.69	0.62	0.00	0.83	0.68	0.73	0.91
plasma cell	1503	0.52	0.62	0.80	0.81	0.00	0.76	0.65	0.67	0.79
lymphocyte	1428	0.23	0.23	0.69	0.61	0.00	0.86	0.32	0.47	0.74
naive T cell	1422	0.82	0.86	0.92	0.92	0.00	0.90	0.89	0.91	0.92
kidney loop of Henle thick ascending limb epithelial cell	1413	0.92	0.92	0.94	0.88	0.00	0.90	0.95	0.96	0.96
immature B cell	1268	0.70	0.70	0.77	0.78	0.00	0.70	0.62	0.75	0.89
alveolar macrophage	1232	0.95	0.95	0.95	0.93	0.00	0.94	0.97	0.96	0.98
endothelial cell of hepatic sinusoid	1168	0.96	0.95	0.88	0.88	0.00	0.94	0.97	0.97	0.98
lung macrophage	1060	0.83	0.04	0.68	0.92	0.00	0.93	0.90	0.86	0.96
non-classical monocyte	1045	0.56	0.68	0.85	0.82	0.00	0.91	0.84	0.78	0.86
endocardial cell	940	0.92	0.91	0.93	0.88	0.00	0.79	0.96	0.87	0.96
double negative thymocyte	866	0.57	0.00	0.63	0.76	0.00	0.84	0.79	0.82	0.91
late pro-B cell	851	0.78	0.78	0.86	0.85	0.00	0.88	0.78	0.87	0.95
kidney collecting duct principal cell	837	0.69	0.88	0.93	0.89	0.00	0.92	0.97	0.96	0.96
basal epithelial cell of tracheobronchial tree	838	0.86	0.73	0.94	0.81	0.00	0.75	0.94	0.87	0.96
mesenchymal cell	788	0.19	0.00	0.43	0.29	0.00	0.40	0.53	0.57	0.53
pancreatic A cell	750	0.63	0.72	0.85	0.89	0.00	0.87	0.95	0.94	0.93
adventitial cell	752	0.65	0.54	0.90	0.42	0.00	0.82	0.80	0.69	0.91
epithelial cell	712	0.40	0.03	0.84	0.67	0.00	0.76	0.67	0.69	0.82
kidney distal convoluted tubule epithelial cell	664	0.80	0.87	0.92	0.80	0.00	0.92	0.97	0.97	0.95
neutrophil	632	0.50	0.47	0.76	0.79	0.00	0.58	0.68	0.63	0.80
pancreatic ductal cell	594	0.98	0.78	0.98	0.95	0.00	0.96	0.97	0.97	0.98
myeloid dendritic cell	564	0.34	0.52	0.82	0.60	0.00	0.78	0.78	0.65	0.75
astrocyte	522	0.89	0.93	0.97	0.95	0.00	0.96	0.99	0.99	0.98
secretory cell	511	0.26	0.33	0.81	0.69	0.00	0.85	0.93	0.89	0.93
myeloid leukocyte	456	0.57	0.31	0.82	0.57	0.00	0.84	0.55	0.68	0.92
plasmatocyte	448	0.57	0.81	0.90	0.84	0.00	0.90	0.94	0.87	0.96
brain pericyte	428	0.00	0.73	0.67	0.87	0.00	0.94	0.96	0.92	0.99
neuron	436	0.62	0.59	0.81	0.80	0.00	0.90	0.96	0.91	0.95
vein endothelial cell	423	0.62	0.76	0.82	0.65	0.00	0.74	0.91	0.83	0.92
kidney collecting duct epithelial cell	414	0.00	0.51	0.89	0.81	0.00	0.92	0.85	0.90	0.95
pancreatic D cell	417	0.00	0.64	0.84	0.89	0.00	0.94	0.97	0.96	0.98
aortic endothelial cell	420	0.16	0.00	0.30	0.39	0.00	0.71	0.39	0.32	0.68
brush cell	377	0.82	0.60	0.94	0.91	0.00	0.92	0.86	0.85	0.91
erythroid progenitor cell, mammalian	361	0.59	0.00	0.67	0.80	0.00	0.81	0.79	0.66	0.94
regular atrial cardiac myocyte	362	0.00	0.40	0.69	0.70	0.00	0.58	0.70	0.75	0.86
kidney cortex artery cell	341	0.00	0.83	0.76	0.52	0.00	0.62	0.83	0.67	0.84
erythrocyte	312	0.61	0.47	0.71	0.86	0.00	0.84	0.83	0.87	0.94
mesangial cell	322	0.00	0.69	0.69	0.69	0.00	0.85	0.88	0.80	0.95
kidney loop of Henle ascending limb epithelial cell	312	0.47	0.59	0.69	0.56	0.00	0.74	0.86	0.85	0.78
cardiac muscle cell	302	0.60	0.68	0.87	0.96	0.00	1.00	0.99	0.97	0.98
mature alpha-beta T cell	293	0.00	0.08	0.40	0.41	0.00	0.68	0.62	0.62	0.88
basophil	292	0.63	0.63	0.88	0.81	0.00	0.68	0.69	0.75	0.84
cardiac valve cell	293	0.66	0.83	0.75	0.82	0.00	0.83	0.94	0.91	0.92
oligodendrocyte precursor cell	283	0.91	0.96	0.98	0.97	0.00	0.97	1.00	0.99	1.00
Schwann cell	252	0.72	0.71	0.82	0.86	0.00	0.92	0.86	0.82	0.82
pulmonary interstitial fibroblast	248	0.87	0.82	0.91	0.87	0.00	0.91	0.96	0.96	0.96
smooth muscle cell of trachea	227	0.00	0.04	0.46	0.57	0.00	0.64	0.65	0.74	0.85
granulocyte monocyte progenitor cell	222	0.50	0.57	0.86	0.80	0.00	0.63	0.81	0.74	0.85
interneuron	215	0.00	0.55	0.82	0.76	0.00	0.90	0.97	0.92	0.95
pancreatic PP cell	205	0.00	0.06	0.69	0.78	0.00	0.80	0.92	0.93	0.92
smooth muscle cell of the pulmonary artery	183	0.00	0.69	0.81	0.57	0.00	0.35	0.89	0.75	0.88
cell of skeletal muscle	176	0.95	0.92	0.77	0.93	0.00	0.91	0.96	0.95	0.96
Langerhans cell	157	0.83	0.80	0.90	0.79	0.00	0.65	0.87	0.78	0.96
brush cell of epithelium proper of large intestine	165	0.00	0.70	0.85	0.85	0.00	0.81	0.99	0.95	0.95
stem cell of epidermis	160	0.00	0.00	0.72	0.64	0.00	0.40	0.67	0.64	0.85
regulatory T cell	157	0.00	0.03	0.23	0.30	0.00	0.41	0.46	0.38	0.76
epithelial cell of thymus	149	0.00	0.01	0.75	0.53	0.00	0.39	0.79	0.61	0.92
enteroendocrine cell	153	0.84	0.74	0.86	0.72	0.00	0.95	0.97	0.96	0.96
kidney capillary endothelial cell	142	0.17	0.49	0.33	0.37	0.00	0.28	0.27	0.34	0.29
neuroepithelial stem cell	135	0.21	0.11	0.88	0.67	0.00	0.60	0.88	0.67	0.87
macrophage dendritic cell progenitor	139	0.00	0.29	0.81	0.79	0.00	0.79	0.73	0.75	0.90
DN3 thymocyte	130	0.00	0.00	0.48	0.77	0.00	0.76	0.77	0.80	0.90
regular ventricular cardiac myocyte	137	0.00	0.00	0.90	0.86	0.00	0.65	0.97	0.98	0.99
endothelial cell of lymphatic vessel	135	0.00	0.45	0.95	0.57	0.00	0.44	0.74	0.51	0.91
ciliated columnar cell of tracheobronchial tree	111	0.82	0.76	0.84	0.90	0.00	0.73	0.98	0.94	0.98
plasmacytoid dendritic cell	109	0.00	0.29	0.87	0.67	0.00	0.46	0.66	0.55	0.78
dendritic cell	97	0.00	0.35	0.77	0.54	0.00	0.53	0.80	0.62	0.83
medium spiny neuron	89	0.00	0.00	0.86	0.79	0.00	0.89	1.00	0.99	0.99
pericyte	83	0.00	0.85	0.83	0.77	0.00	0.91	0.86	0.90	0.93
neural stem cell	87	0.00	0.65	0.85	0.87	0.00	0.93	0.96	0.97	0.98
kidney proximal straight tubule epithelial cell	87	0.00	0.00	0.14	0.00	0.00	0.52	0.73	0.43	0.36
blood cell	79	0.16	0.00	0.43	0.28	0.00	0.20	0.38	0.35	0.38
immature NK T cell	76	0.00	0.09	0.32	0.38	0.00	0.50	0.53	0.50	0.72
cardiac neuron	71	0.00	0.08	0.72	0.63	0.00	0.72	0.78	0.76	0.87
mast cell	64	0.00	0.00	0.59	0.82	0.00	0.35	0.66	0.62	0.79
mucus secreting cell	65	0.00	0.34	0.78	0.68	0.00	0.85	0.90	0.97	0.98
early pro-B cell	66	0.00	0.48	0.76	0.72	0.00	0.39	0.79	0.68	0.87
pancreatic stellate cell	60	0.00	0.61	0.93	0.40	0.00	0.36	0.79	0.81	0.96
ependymal cell	50	0.00	0.59	0.95	0.89	0.00	0.65	1.00	1.00	1.00
Bergmann glial cell	50	0.00	0.43	0.86	0.81	0.00	0.57	1.00	1.00	0.95
neuroendocrine cell	41	0.00	0.00	0.20	0.49	0.00	0.70	0.98	0.77	0.59
fibrocyte	39	0.00	0.00	0.30	0.31	0.00	0.41	0.80	0.76	0.77
hepatic stellate cell	34	0.00	0.21	0.52	0.77	0.00	0.54	0.91	0.93	0.96
club cell	30	0.11	0.45	0.19	0.11	0.00	0.17	0.19	0.18	0.16
respiratory basal cell	32	0.00	0.00	0.95	0.75	0.00	0.26	0.96	0.89	0.95
kidney interstitial fibroblast	15	0.00	0.00	0.97	0.77	0.00	0.40	0.75	0.83	1.00
lymphoid lineage restricted progenitor cell	12	0.00	0.00	0.91	0.53	0.00	0.56	0.04	0.86	0.91
lung neuroendocrine cell	8	0.00	0.00	0.82	0.22	0.00	0.64	0.21	1.00	0.86
kidney cell	3	0.00	0.00	0.00	0.00	0.00	0.16	0.05	0.50	0.50
duct epithelial cell	2	0.00	0.00	0.00	0.00	0.00	0.10	0.31	0.67	0.00

References

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