|
--- |
|
title: README |
|
emoji: 🦠 |
|
colorFrom: green |
|
colorTo: yellow |
|
sdk: static |
|
pinned: false |
|
thumbnail: >- |
|
https://cdn-uploads.huggingface.co/production/uploads/6572ef05cba827dcf8318dad/vdCkUb1iGQJKh3hEts8x3.png |
|
--- |
|
# Systems Chemical Biology of Infection and Resistance Laboratory |
|
|
|
<img src="https://cdn-uploads.huggingface.co/production/uploads/6572ef05cba827dcf8318dad/vdCkUb1iGQJKh3hEts8x3.png" alt="Logo of SCBIR lab" width="300"> |
|
|
|
The SCBIR lab is based the [Francis Crick Institute](https://crick.ac.uk) in London. We use large-scale genetics and chemical biology to study |
|
how pathogenic bacteria infect and evolve resistance to antibiotics. |
|
|
|
Ultimately, we aim to enable antimicrobial therapies which exploit key weaknesses in the ability of pathogenic bacteria to infect and evolve resistance to antibiotics. |
|
|
|
Our work focuses on these areas (click the links for more information): |
|
|
|
- [Accelerating discovery of new small molecules with new targets](https://www.scbir.org/research.html#accelerating-discovery-of-new-small-molecules-with-new-targets) |
|
- [Rapid target annotation](https://www.scbir.org/research.html#rapid-target-annotation) |
|
- [Optimising chemical library design](https://www.scbir.org/research.html#optimising-chemical-library-design) |
|
- [Defining targets for bacterial survival and infection](https://www.scbir.org/research.html#defining-targets-for-bacterial-survival-and-infection) |
|
|
|
Find out more about our research [here](https://scbir.org)! |