README.md

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license: cc-by-nc-nd-4.0
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MeMDLM: De Novo Membrane Protein Design with Masked Diffusion Language Models

Masked Diffusion Language Models (MDLMs), introduced by Sahoo et al (arxiv.org/pdf/2406.07524), provide strong generative capabilities to BERT-style models. In this work, we pre-train and fine-tune ESM-2-150M on the MDLM objective to unconditionally generate realistic, high-quality membrane protein sequences.