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Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. It is moderately effective: about 30–40% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a meaningful benefit. Sleepiness and dizziness are the most common side effects. Serious side effects include an increased risk of suicide, respiratory depression, and allergic reactions. Lower doses are recommended in those with kidney disease. Gabapentin acts by decreasing activity of a subset of calcium channels. Gabapentin was first approved for use in 1993. It has been available as a generic medication in the United States since 2004. In 2022, it was the tenth most commonly prescribed medication in the United States, with more than 40 million prescriptions. During the 1990s, Parke-Davis, a subsidiary of Pfizer, used a number of illegal techniques to encourage physicians in the United States to prescribe gabapentin for unapproved uses. They have paid out millions of dollars to settle lawsuits regarding these activities.
胞嘧啶(C)(英語:cytosine),學名為2-羰基-4-氨基嘧啶,是组成DNA的四种基本碱基之一。胞嘧啶核苷、胞嘧啶核苷酸均可作为升高白细胞(白血球)的药物。可由2-硫脲嘧啶、浓氨水和氯乙酸为原料合成制得。
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Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator. The name "noradrenaline" (from Latin ad, "near", and ren, "kidney") is more commonly used in the United Kingdom, whereas "norepinephrine" (from Ancient Greek ἐπῐ́ (epí), "upon", and νεφρός (nephrós), "kidney") is usually preferred in the United States. "Norepinephrine" is also the international nonproprietary name given to the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic. The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so-called fight-or-flight response. In the brain, norepinephrine increases arousal and alertness, promotes vigilance, enhances formation and retrieval of memory, and focuses attention; it also increases restlessness and anxiety. In the rest of the body, norepinephrine increases heart rate and blood pressure, triggers the release of glucose from energy stores, increases blood flow to skeletal muscle, reduces blood flow to the gastrointestinal system, and inhibits voiding of the bladder and gastrointestinal motility. In the brain, noradrenaline is produced in nuclei that are small yet exert powerful effects on other brain areas. The most important of these nuclei is the locus coeruleus, located in the pons. Outside the brain, norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen, as well as Merkel cells located in the skin. It is also released directly into the bloodstream by the adrenal glands. Regardless of how and where it is released, norepinephrine acts on target cells by binding to and activating adrenergic receptors located on the cell surface. A variety of medically important drugs work by altering the actions of noradrenaline systems. Noradrenaline itself is widely used as an injectable drug for the treatment of critically low blood pressure. Stimulants often increase, enhance, or otherwise act as agonists of norepinephrine. Drugs such as cocaine and methylphenidate act as reuptake inhibitors of norepinephrine, as do some antidepressants, such as those in the SNRI class. One of the more notable drugs in the stimulant class is amphetamine, which acts as a dopamine and norepinephrine analog, reuptake inhibitor, as well as an agent that increases the amount of global catecholamine signaling throughout the nervous system by reversing transporters in the synapses. Beta blockers, which counter some of the effects of noradrenaline by blocking their receptors, are frequently used to treat glaucoma, migraine, and a range of cardiovascular problems. Alpha blockers, which counter a different set of noradrenaline effects, are used to treat several cardiovascular and psychiatric conditions. Alpha-2 agonists often have a sedating effect and are commonly used as anesthesia enhancers in surgery, as well as in treatment of drug or alcohol dependence. For reasons that are still unclear, some Alpha-2 drugs, such as guanfacine, have also been shown to be effective in the treatment of anxiety disorders and ADHD. Many important psychiatric drugs exert strong effects on noradrenaline systems in the brain, resulting in effects that may be helpful or harmful.
二甲双胍最早於1922年發現,但直到1950年代,法國內科醫師讓·斯特恩(Jean Sterne)開啟了二甲双胍人类应用的临床研究。1957年,本品開始在法國用於藥用,並於1995年開始於美國使用。本品列名於世界卫生组织基本药物标准清单之中,為基礎公衛體系必備藥物之一。目前相信口服給藥是最有效的給藥途徑,本品屬於通用名藥物。2014年本品於已開發國家的批發價為0.21至5.55美元之間。在美國,一個月療程的藥物花費約於 5 至 25 美元之間。
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Lysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.
己二酸二辛酯(英語:Dioctyl adipate,缩写DOA)是一种二羧酸二酯,化学式(CH2CH2CO2C8H17)2,常温常压下为无色油状液体,可看做一分子己二酸与两分子正辛醇形成的二酯,常用作塑化剂。
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Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology. It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands.
達泊西汀(INN:dapoxetine),商品名 Priligy 必利劲,属于一种快速起效和代谢的选择性5-羟色胺再吸收抑制剂(SSRI),是一款用于治療16至84周岁男性早泄的藥物,通常可将射精前性交时长延长至原先的3至4倍。
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Canrenone is a steroid lactone.
烏頭鹼(英語:aconitine)是一種生物鹼毒素。是常用中藥烏頭屬中所含有的一種化學物質,具強烈毒性,口服0.2mg左右即能使人中毒,3-5mg即可致死。民间常用草乌、川乌等植物来泡制药酒,但这种药酒可能是极端危险的,也经常因此出现中毒甚至死亡的情况。
0
Taxodone is a diterpenoid.
氨马尿酸(INN:aminohippuric acid),学名:对氨基马尿酸(para-aminohippuric acid,PAH),是一种马尿酸的衍生物,临床上用于测定肾血流量。常用以静脉灌注的形式进行给药。
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Pirbuterol is a member of pyridines.
吡布特罗(INN:pirbuterol;商品名:Maxair)是一种短效β2肾上腺素受体激动药,具有支气管扩张作用,用于治疗哮喘,可(以醋酸吡布特罗形式)作为呼吸激活的定量吸入器。 它于1971年获得专利,并于1983年进入医疗用途。
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Lunularin is a natural product found in Morus macroura, Frullania tamarisci, and other organisms with data available.
半月苔素(英語:Lunularin)是一种分子式为C14H14O2的二氢芪类有机化合物,发现于旱芹绣球等植物中。植物半月苔酸脱羧酶可将半月苔酸脱羧为半月苔素。
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Gramine is an aminoalkylindole that is indole carrying a dimethylaminomethyl substituent at postion 3. It has a role as a plant metabolite, a serotonergic antagonist, an antiviral agent and an antibacterial agent. It is an aminoalkylindole, an indole alkaloid and a tertiary amino compound. It is a conjugate base of a gramine(1+).
乙酸正丁酯,简称乙酸丁酯,结构式CH3C(O)On-C4H9。
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Deacetylvindoline is a terpene indole alkaloid produced by Catharanthus roseus. Deacetylvindoline is the product of a hydroxylation of desacetoxyvindoline by deacetoxyvindoline 4-hydroxylase (D4H). It is a substrate for deacetylvindoline O-acetyltransferase (DAT) which acetylates a hydroxy group to form vindoline, one of the two immediate precursors for the formation of the pharmacetucially valuable bisindole alkaloid vinblastine.
氟柠檬酸是一种氟化羧酸,由柠檬酸中的一个氢被氟原子取代而衍生。 衍生的阴离子称为氟柠檬酸根。 氟柠檬酸盐由氟乙酸盐分两步形成。 氟乙酸首先被线粒体中的乙酰辅酶A合成酶转化为氟乙酰辅酶A。 然后氟乙酰辅酶A与草酰乙酸缩合形成氟柠檬酸。 该步骤由柠檬酸合成酶催化。 氟柠檬酸是氟乙酸的代谢产物,毒性很大,因为它不能在柠檬酸循环(其中氟柠檬酸代替柠檬酸作为底物)中使用顺乌头酸酶进行加工。顺乌头酸酶被氟柠檬酸酶抑制剂抑制,三羧酸循环停止工作。
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Maleimide is a cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure. It has a role as an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. It is a dicarboximide and a member of maleimides. It is functionally related to a maleic acid. It derives from a hydride of a 1H-pyrrole.
糞臭素(英語:Skatole)為一種具有中等毒性的白色結晶有機化合物,是吲哚的一種衍生物,即3-甲基吲哚,化學式 C9H9N。在自然界中,存在於哺乳動物的糞便(為色氨酸在消化系統中的產物)、甜菜與煤焦油中,具有強烈的糞便氣味。在低濃度下,糞臭素具有花香味,並存在於許多花朵與精油中,如橙花、茉莉與滇刺枣,因此被用於香水中的香精、定香劑以及食物香料等。其名稱來自於希臘文的skato-,意指「動物的糞便」。
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Delphinine is a toxic diterpenoid alkaloid found in plants from the Delphinium (larkspur) and Atragene (a clematis) genera, both in the family Ranunculaceae. Delphinine is the principal alkaloid found in Delphinium staphisagria seeds – at one time, under the name stavesacre, a very well known herbal treatment for body lice. It is related in structure and has similar effects to aconitine, acting as an allosteric modulator of voltage gated sodium channels, and producing low blood pressure, slowed heart rate and abnormal heart rhythms. These effects make it highly poisonous (LD50 1.5–3.0 mg/kg in rabbit and dog; frogs are ~10x more susceptible). While it has been used in some alternative medicines (e.g. in herbal medicine), most of the medical community does not recommend using it due to its extreme toxicity.
2NaN3 → 2Na + 3N2
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Guaiazulene is a natural product found in Artemisia thuscula, Magnolia officinalis, and other organisms with data available.
硼酸鹽以許多形式存在。在酸和近中性的環境上,它是硼酸(通常寫成H3BO3,但B(OH)3更為正確)。硼酸在25°C的 p𝘒ₐ為9.14,硼酸雖不會在水溶液中分解,但它卻是酸性,因它會與水分子產生相互作用,形成B(OH)−4: B(OH)3 + H2O ⇌ B(OH)4− + H+ Ka 9.24. 如果硼酸根離子含量高於大约0.025 mol dm−3,多硼酸根離子可於pH 7-10形成。例如,在礦物硼砂中可發現較常見的四硼酸根離子: 4B(OH)4− + 2H+ ⇌ B4O72− + 9H2O 硼酸可以形成許多聚合的離子。 最常見為四硼酸根離子(B4O72−),也可形成四硼酸氫根離子(HB4O7−)、三硼酸根及五硼酸根離子。 此外,各種各樣的偏硼酸根離子的實驗式為BO2−,它們可形成各種偏硼酸鹽化合物,有複雜且可無限伸展之網狀結構,其多樣性可與硅酸鹽相比。
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Methanediol, also known as formaldehyde monohydrate or methylene glycol, is an organic compound with chemical formula CH2(OH)2. It is the simplest geminal diol. In aqueous solutions it coexists with oligomers (short polymers). The compound is closely related and convertible to the industrially significant derivatives paraformaldehyde ((CH2O)n), formaldehyde (H2C=O), and 1,3,5-trioxane ((CH2O)3). Methanediol is a product of the hydration of formaldehyde. The equilibrium constant for hydration is estimated to be 103,CH2(OH)2 predominates in dilute (<0.1%) solution. In more concentrated solutions, it oligomerizes to HO(CH2O)nH.
丙呋甲酮(英語:Tremetone)是一种有机化合物,分子式C13H14O2,存在于假藿香薊屬的物种(Ageratina altissima)中,有毒。
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Spectinomycin is a natural product found in Streptomyces, Streptomyces netropsis, and other organisms with data available.
奇黴素(英語:Spectinomycin),一名大觀黴素,通常以曲必星(Trobicin)為名販售,係為一種用以治療淋病感染症狀的抗生素。投藥方式是注射進肌肉以發揮藥效。 常見的副作用包含注射處疼痛、起疹子、噁心、發燒及睡眠障礙,也可能產生嚴重的過敏反應;孕婦使用此藥通常是安全無虞的,對盤尼西林或頭孢菌素過敏者亦可使用。奇黴素隸屬於氨基環多醇族,運作方式是藉由停止生成蛋白質以遏止特定細菌。 奇黴素於1961年被發現。它被列入世界衛生組織基本藥物標準清單,是基層衛生系統中最重要的藥物之一。批發價大約是5美元每劑,而在美國境內並不流通。奇黴素係利用壯觀黴素所製造出來的。
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Pyridazine is a member of pyridazines and a diazine.
麦芽糖(英語:Maltose)是通过α(1→4)键连接的两个单位的葡萄糖,从缩合反应形成的一种双糖。异构体的异麦芽糖具有通过α(1→6)键连接的两个葡萄糖分子。麦芽糖是淀粉酶分解淀粉产生的双糖。
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Diethyl sulfate (DES) is an organosulfur compound with the formula (C2H5)2SO4. It occurs as a colorless, oily liquid with a faint peppermint odor. It is toxic, combustible, and likely carcinogenic chemical compound. Diethyl sulfate is used as an ethylating agent.
他扎罗汀(INN:tazarotene;商品名:Tazorac)是一种第三代处方外用类视黄醇药物,主要用于治疗銀屑病和痤疮,它也被用于治疗皮肤的光老化和光损伤。
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Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects including stimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth. Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it is an indirectly acting sympathomimetic. Pseudoephedrine significantly crosses into the brain, but has some peripheral selectivity due to its hydrophilicity. Chemically, pseudoephedrine is a substituted amphetamine and is closely related to ephedrine, phenylpropanolamine, and amphetamine. It is the (1S,2S)-enantiomer of β-hydroxy-N-methylamphetamine. Along with ephedrine, pseudoephedrine occurs naturally in ephedra, which has been used for thousands of years in traditional Chinese medicine. It was first isolated from ephedra in 1889. Subsequent to its synthesis in the 1920s, pseudoephedrine was introduced for medical use as a decongestant. Pseudoephedrine is widely available over-the-counter (OTC) in both single-drug and combination preparations. Availability of pseudoephedrine has been restricted starting in 2005 as it can be used to synthesize methamphetamine. Phenylephrine has replaced pseudoephedrine in many over-the-counter oral decongestant products. However, oral phenylephrine appears to be ineffective as a decongestant.
苯丙酮是一种有机化合物,为无色、有香甜气味的液体,难溶于水,和有机溶剂混溶。
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Probucol is a dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood. It has a role as an anticholesteremic drug, an antioxidant, an anti-inflammatory drug, a cardiovascular drug and an antilipemic drug. It is a dithioketal and a polyphenol.
氟奋乃静(Fluphenazine),常見商品名Prolixin,為一種精神科藥物,用于治疗包括精神分裂症在內的慢性思覺失調,並與氯丙嗪等低潛能的藥品效果相似。本品可透過口服、肌肉注射,以及皮下注射給藥。長效針劑的藥效可持續最多四周。憂鬱症重症患者不適合使用癸酸針劑型。 常見副作用包含運動障礙、昏睡、抑郁,以及體重增加。嚴重副作用則包含抗精神藥物惡性症候群、白细胞减少症。以及永久性的運動障礙遲發性運動不能。失智症造成精神錯亂的年長者服藥可能增加死亡風險。本品也會增加催乳素分泌,導致乳溢症、男性乳房發育、陽痿,或是無月經。妊娠期間用藥的安全性尚不清楚,本品屬於吩噻嗪類典型抗精神病藥物。其作用機轉迄今仍不清楚,可能與其具有多巴胺受體拮抗劑的活性有關。長期服用吩噻嗪類藥物者,有40%的患者肝功能測試會有異常的情形。 氟奋乃静於1959年開始作為藥物使用。其針劑性列名於世界卫生组织基本药物标准清单之中,為基礎公衛體系必備藥物之一。本品屬通用名药物,在美國每日正常劑量的口服藥錠批發價約介於0.22至0.42美金之間。2014年,在发展中国家同樣劑量的針劑型批發價介於0.20至6.20美金之間。在2017年終,澳大利亞已不再進口此一藥物。
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Aristolochic acids (English: ) are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts). Aristolochic acid (AA) I is the most abundant one. The family Aristolochiaceae includes the genera Aristolochia and Asarum (wild ginger), which are commonly used in Chinese herbal medicine. Although these compounds are widely associated with kidney problems, liver and urothelial cancers, the use of AA-containing plants for medicinal purposes has a long history. The FDA has issued warnings regarding consumption of AA-containing supplements.
阿夫唑嗪(英语:Alfuzosin),或译阿呋唑嗪,以Uroxatral等商品名出售,是一种α1阻滞剂类药物。它用于治疗良性前列腺增生。 作为α1肾上腺素受体的拮抗剂,它的作用是放松前列腺和膀胱颈的肌肉,使排尿更容易。 阿夫唑嗪于1978年获得专利,并于1988年被批准用于医疗用途。它于2003年在美国被批准用于治疗良性前列腺增生。2020年,它是美国第336位最常用药物,处方数量超过70万张。
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Cafestol is an organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). It has a role as a plant metabolite, an apoptosis inducer, a hypoglycemic agent, an angiogenesis inhibitor, an antineoplastic agent, an antioxidant and an anti-inflammatory agent. It is an organic heteropentacyclic compound, a tertiary alcohol, a diterpenoid, a member of furans and a primary alcohol.
维生素A1(英語:Retinol)又称为视黄醇是維生素A的動物形式之一,它是一個二萜和醇的結構,它可以轉換為其他形式的維生素A,並且以醇的衍生物視黃酯充當動物中維生素的儲存形式。 當轉換為視黃醛的形式,維生素A對視力是必不可少的,當轉換成視黃酸對皮膚健康、牙齒礦化和骨骼生長所必需。這些化學化合物統稱為類維生素A,並具有全反式視黃醇作為其結構的一個結構基序的共同特徵。在結構上類維生素A還具有一個β–紫羅蘭酮環和不飽和側鏈,與任一醇、醛、羧酸基或酯基。側鏈由四個類異戊二烯單元組成,以一系列可能存在於反式或順式構型的共軛雙鍵。 它是人体必需的13种维生素之一,是一种脂溶性抗氧化剂,在人体中可以维持视力并且促进骨骼成长。 維生素A並非單一的一種化合物,而是有許多不同的型態。动物能将胡萝卜素在体内转化为维生素A贮藏在肝脏中;通常是以醇類的方式存在,稱作視黃醇,活性也是最高;但也有一些屬於醛類,稱作視黃醛;另外還有一些屬於酸類,稱作視黃酸。 視黃醇與視黃醛主要掌管桿細胞的視覺循環,而視黃酸主要是掌管人體內上皮組織分化有關,因此有些視黃酸衍伸物(俗稱的A酸)常用於皮膚疾病上的治療,另外有一種稱作視黃酯,其為人體內儲存脂溶性維他命A的主要型式。
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Formate is a monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It is a conjugate base of a formic acid.
普鲁卡因胺(INN:Procainamide,發音: /proʊˈkeɪnəmaɪd/)是一种Ia类抗心律失常药,用于治疗心律不整。
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Aconitic acid is a tricarboxylic acid that is prop-1-ene substituted by carboxy groups at positions 1, 2 and 3. It is a conjugate acid of an aconitate(3-).
乌头酸(英語:Aconitic acid)是一种有机酸,其两种异构体分别是顺乌头酸与反乌头酸。顺乌头酸的共轭碱,顺乌头酸盐是三羧酸循环中柠檬酸盐异构化为异柠檬酸盐的中间产物。这一步骤的催化酶是顺乌头酸酶。 (HO2CCH2)2COH(CO2H) → HO2CCH=C(CO2H)CH2CO2H + H2O
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(S)-naringenin is the (S)-enantiomer of naringenin. It has a role as an expectorant and a plant metabolite. It is a naringenin and a (2S)-flavan-4-one. It is a conjugate acid of a (S)-naringenin(1-). It is an enantiomer of a (R)-naringenin.
硝酸銨是一種化合物,是銨陽離子的硝酸鹽。它的化學式是 NH 4 NO 3 (簡化為 N 2 H 4 O 3 ),是一種白色的結晶固體,在水中溶解度高。它在农业上主要作為高氮肥料使用。其他用途是作為採礦、採石和土木建築中使用的爆炸混合物的成分之一。它也是铵油炸药的主要成分,這是一種普遍的工業炸藥,佔北美炸藥的80%。類似的配方也用於簡易爆炸裝置(IED,俗稱土製炸彈)。由於擔心有被誤用的可能性,許多國家正把它從消費性應用中階段性淘汰。
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Ambroxol is an aromatic amine.
双酪氨酸(英語:Dityrosine)是一种非蛋白胺基酸,能作为酪氨酸的二聚體,分子式C18H20N2O6,CYP56A1、髓过氧化物酶等酶能催化蛋白质上的酪氨酸残基生成酪氨酸-酪氨酸交叉鏈接。
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Lactamide is a monocarboxylic acid amide that is lactic acid in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a monocarboxylic acid amide and a secondary alcohol. It is functionally related to a rac-lactic acid.
乳醯胺是一種衍生自乳酸的醯胺,其和乳酸一樣具有手性碳。乳醯胺在常壓下熔點範圍為73-76 °C。
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Methyl acetate is an acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 ###) colourless, flammable liquid, it is used as a solvent for many resins and oils. It has a role as a polar aprotic solvent, a fragrance and an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor. It is an acetate ester, a methyl ester and a volatile organic compound.
乙酸甲酯,分子式CH3COOCH3,是一种有机酸酯,亦称作醋酸甲酯。
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2-Hexanone (methyl butyl ketone, MBK) is a ketone used as a general solvent and in paints. It dissolves cellulose nitrate, vinyl polymers and copolymers, and natural and synthetic resins. It is recommended as a solvent because it is photochemically inactive; however it has a very low safe threshold limit value. 2-Hexanone is absorbed through the lungs, orally and dermally and its metabolite, 2,5-hexanedione, is neurotoxic. Animal tests have shown that the neurotoxic effect of 2-hexanone may be potentiated by simultaneous administration of 2-butanone (methyl ethyl ketone, MEK).
阿米洛利 (英語:Amiloride)以商品名Midamor等於市面銷售,是種通常與其他藥物一起使用以治療高血壓,或是因心臟衰竭或肝硬化引發水腫的藥物。此藥物屬於一種保鉀利尿劑。阿米洛利經常與另一利尿劑(例如噻嗪類利尿劑或環利尿劑)一起使用。此藥物經由口服的方式給藥。攝入後約兩小時開始發生作用,效力約可持續一天。
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Ergotamine, sold under the brand name Ergomar among others, is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline. It is structurally similar to several neurotransmitters, and it acts as a vasoconstrictor. It is used for acute migraines, sometimes with caffeine as the combination ergotamine/caffeine. Medicinal use of ergot fungus began in the 16th century, for the induction of childbirth; but dosage uncertainty discouraged its use. It has been used to prevent post-partum hemorrhage (bleeding after childbirth). It was first isolated from the ergot fungus by Arthur Stoll, at Sandoz in 1918, and was marketed as Gynergen in 1921.
它用于医学上用于治疗急性偏头痛发作(有时与咖啡因共用)。麦角真菌的药物使用始于16世纪诱导分娩,但其剂量的不确定性阻止了使用。它已被用于防止产后出血(分娩后出血)。它首先在1918年被Sandoz的Arthur Stoll从麦角真菌中分离出来,1921年以商品名Gynergen销售.
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Tris(2-chloroethyl) phosphate is a trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid. It is a trialkyl phosphate and an organochlorine compound.
分支酸(英語:Chorismic acid)是一种在植物和许多微生物中重要的生物化学中间体,是一个生物合成前体,用于合成: 其名称chorismic来自于一个古典希腊词:χωρίζω 意思是“分开”,因为该化合物是芳香族氨基酸与其它物质的生物合成途径的分支点。
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Sulfathiazole is a 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position. It has a role as an antiinfective agent, an environmental contaminant, a xenobiotic, an EC 2.5.1.15 (dihydropteroate synthase) inhibitor and a drug allergen. It is a member of 1,3-thiazoles, a sulfonamide, a substituted aniline and a sulfonamide antibiotic. It is functionally related to a sulfanilamide.
脫氫抗壞血酸(Dehydroascorbic acid, DHA)是氧化形式的抗壞血酸(維生素C)。
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Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient for humans and animals. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids. Food sources of thiamine include whole grains, legumes, and some meats and fish. Grain processing removes much of the vitamin content, so in many countries cereals and flours are enriched with thiamine. Supplements and medications are available to treat and prevent thiamine deficiency and the disorders that result from it such as beriberi and Wernicke encephalopathy. They are also used to treat maple syrup urine disease and Leigh syndrome. Supplements and medications are typically taken by mouth, but may also be given by intravenous or intramuscular injection. Thiamine supplements are generally well tolerated. Allergic reactions, including anaphylaxis, may occur when repeated doses are given by injection. Thiamine is on the World Health Organization's List of Essential Medicines. It is available as a generic medication, and in some countries as a non-prescription dietary supplement.
硫胺主要扮演食物中的糖與醣類(澱粉)在消化過程中的處理角色,最後產生能量;同時作為肌肉協調及維持神經傳導之需。維生素B1亦有中度的利尿作用。硫胺不够稳定,遇热、紫外线、氧气都会发生化学反应,分解或变质。硫胺可以溶于水,不溶于醇等有机溶剂。常温下在pH值为3.5的水溶液中稳定,而在中性和碱性溶液中会发生分解。通常会被制作为盐酸盐(C12H18Cl2N4OS,CAS No.67-03-8)、硝酸盐(C12H17N5O4S,CAS No.532-43-4)等较稳定的形式来使用。
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Dydrogesterone, sold under the brand name Duphaston among others, is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal hormone therapy. It is taken by mouth. Side effects of dydrogesterone include menstrual irregularities, headache, nausea, breast tenderness, and others. Dydrogesterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. The medication is an atypical progestogen and does not inhibit ovulation. It has weak antimineralocorticoid activity and no other important hormonal activity. Dydrogesterone was developed in the 1950s and introduced for medical use in 1961. It is available widely throughout Europe, including in the United Kingdom, and is also marketed in Australia and elsewhere in the world. The medication was previously available in the United States, but it has been discontinued in that country.
新烟裂碱(英語:Anabaseine)又称假木贼因,学名3,4,5,6-四氢-2,3′-联吡啶。其为一种从海洋纽虫和长脚家蚁产生的有毒生物碱。 在结构上与尼古丁和假木贼碱相似,对中枢和外周神经系统中大多数烟碱型乙酰胆碱受体可同样起到激动剂作用。
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Ethyl propionate is a propanoate ester of ethanol. It has a role as a metabolite.
達普頌 (英語:Dapsone),也稱為4,4'-磺酰二苯胺(SDA) 或二氨基二苯碸(DDS),是一種抗生素(抗細菌藥),常與利福平和氯法齊明聯合用於治療痲瘋病。它是種治療和預防肺囊蟲肺炎,以及免疫缺陷者於預防弓蟲症時使用的二線藥物。此外它還用於治療痤瘡、皰疹樣皮膚炎和各種其他形式的皮膚病。達普頌有口服形式,也有用於塗抹的凝膠形式(外用藥物)。 使用後的嚴重副作用有白血球減少症、溶血反應,尤其是對葡萄糖-6-磷酸去氫酶缺乏症 (G-6-PD) 或對達普頌有過敏反應者。常見的副作用有噁心和食慾不振。其他副作用有肝炎、正鐵血紅蛋白血症和多種皮疹。雖然懷孕期間的個體使用對胎兒的安全性尚不完全清楚,但一些醫生建議麻風病患者繼續使用。它是種碸類藥物。
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2-acetylpyrazine is a pyrazine that is substituted by an acetyl group at position 2. It has been identified as one of the volatile flavor constituents in popcorn, bread crust, vinegar, and potato snacks. It has a role as a flavouring agent. It is an aromatic ketone and a member of pyrazines.
乙酰基吡嗪(又称2-乙酰基吡嗪)是一种吡嗪和酮,化学式为C6H6N2O。在常温下,乙酰基吡嗪呈黄色至褐色粉末。 乙酰基吡嗪存在于一些食物中,比如种子、坚果和肉。它可以用于一些冷冻乳制品,如冰淇淋中。美国食品药品监督管理局将乙酰基吡嗪分类为“公认安全”。
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Panaxatriol is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides. It is a dammarane-type tetracyclic triterpene sapogenin found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). It is formed by the dehydration of protopanaxatriol.
阿巴卡維(英語:Abacavir,簡稱 ABC )是預防及治療愛滋病的藥物。本品屬於核苷類反轉錄酶抑制劑(NRTI 藥物),藉由阻斷人類免疫缺乏病毒(HIV)必需的反轉錄酶發揮藥效。NRTI 類的藥品需要和抗反轉錄病毒藥物一起使用,不建議單獨使用。本品可製成藥錠口服給藥,也可以溶解後服用;三個月以上的嬰幼兒亦適用此藥。 1988 年,阿巴卡維取得專利,1998 年在美國通過審核,名列世界衛生組織基本藥物標準清單,認可為醫療系統中最安全有效的必需藥物之一,並已有學名藥問世。2014 年,開發中國家的單日劑量批發價約在 0.36~0.83 美元之譜,2016 年,美國的單月劑量批發價為 70.50 美元。通常市販的阿巴卡維藥物會跟其他 HIV 藥物一起搭配,例如阿巴卡維/拉米夫定/齊多夫定、阿巴卡維/度魯特韋/拉米夫定、阿巴卡維/拉米夫定等。
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Glutaric acid is an alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. It has a role as a human metabolite and a Daphnia magna metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is a conjugate acid of a glutarate(1-) and a glutarate.
吲达品是选择性血清素再摄取抑制剂(SSRI)及抗组胺药。他曾是在法国及其它欧洲国家短暂上市的抗抑郁药。 吲达品于1977年发现,1983年在法国用作药物。不过,它在两年后就因其毒性从市场撤回。虽然有来源称吲达品是首个被发现的SSRI,但在吲达品之前就已发现另一种SSRI——齐美定。它在1969年发现,于1981年进入市场,后来于1983年因毒性撤回。
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Ecdysone is a 6-oxo steroid that is 5beta-cholest-7-en-6-one substituted by hydroxy groups at positions 2, 3, 14, 22 and 25 respectively (the 2beta, 3beta, 22R stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone. It has a role as a prohormone. It is a 2beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid, a 6-oxo steroid, a 3beta-sterol and an ecdysteroid. It derives from a hydride of a 5beta-cholestane.
蜕皮酮或为蜕皮甾酮(英語:Ecdysone)是一种昆虫的类固醇激素原,是涉及昆虫蜕皮的主要激素20-羟基蜕皮酮的前体,由前胸腺分泌。蜕皮酮与其衍生物等统称为蜕皮激素,作用于节肢动物与相关门类起到蜕皮与其它作用。在黑腹果蝇(Drosophila melanogaster)中,蜕皮酮浓度的增加会诱导编码幼虫蜕皮所需基因的蛋白表达,并导致染色体膨大和多線染色體(polytene chromosomes)形成。Chris Q. Doe的实验室最近发现了蜕皮酮在果蝇的神經幹細胞中的新作用。
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Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.
环丁酸醇(英語:Cyclobutyrol,缩写CB)是一种治疗胆汁的药物,分子式C10H18O3,作为一种利胆剂能抑制胆脂的分泌。 它可以丁酸和环己酮为原料,在二异丙基氨基锂的存在下反应制得。
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Picrocrocin is a beta-D-glucoside of beta-cyclocitral; the precursor of safranal. It is the compound most responsible for the bitter taste of saffron. It is functionally related to a beta-cyclocitral.
苯甲腈是具有示性式C6H5CN的芳香化合物,简写为PhCN。苯甲腈是一种無色,有甜杏仁味的液体。它可以通过苯甲酰胺脱水或者通过氰化钠和溴苯反应制备。
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Salsolinol is a natural product found in Portulaca oleracea and Aristolochia arcuata with data available.
佛波酯(phorbol esters)是一类能促進腫瘤生長的有机化合物,有時會被使用在生物學實驗當中,作為二酰甘油的类似物,激活蛋白激酶C(protein kinase c)。由于佛波酯很难被代谢掉,因此这种激活作用是持续性的,将最终导致细胞的癌变。 佛波醇-12-十四烷酰-13-乙酸酯(phorbol myristoyl acetate;PMA)是其中較常見的一種。
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2,3,5-Trimethylpyrazine is a natural product found in Camellia sinensis, Streptomyces antioxidans, and other organisms with data available.
脫氫抗壞血酸(Dehydroascorbic acid, DHA)是氧化形式的抗壞血酸(維生素C)。
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Chlorothiazide is 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension. It has a role as a diuretic and an antihypertensive agent.
一种源自Euphorbia pedroi植物的化合物pedrolide中的“佩德罗烷”(pedrolane)环可由惕各烷(环)通过生物合成得到。
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Trimethylolpropane triacrylate is a carbonyl compound.
椭圆玫瑰树碱(ellipticine)是一种细胞毒生物碱,由吲哚与异喹啉稠合。
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1-Hexene (hex-1-ene) is an organic compound with the formula C6H12. It is an alkene that is classified in industry as higher olefin and an alpha-olefin, the latter term meaning that the double bond is located at the alpha (primary) position, endowing the compound with higher reactivity and thus useful chemical properties. 1-Hexene is an industrially significant linear alpha olefin. It is a colourless liquid.
阿普唑仑(INN:alprazolam),商品名贊安諾(Xanax),是三唑并苯二氮䓬类中的中效速效镇静剂,它是与三唑环融合的苯二氮䓬类 (BZD)。它最常用于焦虑症的短期管理,特别是恐慌症或广泛性焦虑症 (GAD)。其他用途包括治疗化疗引起的恶心,以及其他治疗方法。GAD 改善一般在一周内发生。阿普唑仑通常口服。
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Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life on Earth. Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP. Cyclic adenosine monophosphate (cAMP) is pervasive in signal transduction. Adenosine is used as an intravenous medication for some cardiac arrhythmias. Adenosyl (abbreviated Ado or 5'-dAdo) is the chemical group formed by removal of the 5′-hydroxy (OH) group. It is found in adenosylcobalamin (an active form of vitamin B12) and as a radical in the radical SAM enzymes.
4-氨基萘-1-磺酸是一种有机化合物,化学式为C10H6(SO3H)(NH2)。它是几种氨基萘磺酸中的一种,是同时含有胺和磺酸官能团的萘衍生物。它是一种白色固体,尽管商业样品可能呈灰色。它用于合成偶氮染料,例如酸性红88,在此过程中,该酸的氨基(以盐的形式)被重氮化,然后与上述情况下的β-萘酚偶联。它可由1-氨基萘用硫酸处理制得。
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Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is a sesquiterpenoid, a cyclic acetal, an organic peroxide, an artemisinin derivative and a semisynthetic derivative.
雙胍類(英語:biguanides)是一群主要用于治疗2型糖尿病的口服降糖药;这群有机化合物皆为原型「雙胍」(化学式 HN(C(NH)NH2)2)的衍生物。雙胍原型为一种无色固体,溶于水后会产生强碱性溶液,接着再缓慢地水解成氨和尿素。 聚氨丙基雙胍(Polyaminopropyl Biguanide):為殺菌劑、防腐劑
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Phenolphthalein ( feh-NOL(F)-thə-leen) is a chemical compound with the formula C20H14O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in acid–base titrations. For this application, it turns colorless in acidic solutions and pink in basic solutions. It belongs to the class of dyes known as phthalein dyes. Phenolphthalein is slightly soluble in water and usually is dissolved in alcohols in experiments. It is a weak acid, which can lose H+ ions in solution. The nonionized phenolphthalein molecule is colorless and the double deprotonated phenolphthalein ion is fuchsia. Further proton loss in higher pH occurs slowly and leads to a colorless form. Phenolphthalein ion in concentrated sulfuric acid is orange red due to sulfonation.
哌美克隆(英語:Pimeclone,商品名:Karion 或 Spiractin)是一种有机化合物,分子式C12H21NO,带有1-哌啶基,可用作呼吸兴奋剂,1927年首次合成。
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Acetate is a monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It is a conjugate base of an acetic acid.
氢化锂(化学式:LiH)是锂的氢化物。它是无色晶体,通常带有杂质而呈灰色。氢化锂属于类盐氢化物,熔点很高(689°C)且对热稳定。比热容为29.73 J/mol*k,导热性随温度升高而下降,随组成和压力的变化也有不同(10~5 W/m*K,400 K)。 LiH + H2O → LiOH + H2
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Styrene is a vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species. It has a role as a mutagen, a plant metabolite and a mouse metabolite. It is a vinylarene, a volatile organic compound and a member of styrenes.
醋地砜(INN:Acediasulfone)是一种抗菌药物,也具有抗疟活性。它是氨苯砜的长效前药,可用于治疗麻风病。
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Hentriacontane is a long-chain alkane. It has a role as an antitubercular agent.
三十一烷(英語:Hentriacontane,也稱untriacontane)是一個結構式為CH3(CH2)29CH3的固體長鏈烷烴。很多植物(如豌豆)上都含有三十一烷,而蜂蠟含有8-9%的三十一烷。三十一烷有10,660,307,791种同分異構體。
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Glyphosate is a phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS). It has a role as an agrochemical, an EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor and a herbicide. It is a phosphonic acid and a glycine derivative. It is a conjugate acid of a glyphosate(2-) and a glyphosate(1-).
農民很快接受草甘膦,特別是在孟山都推出了抗草甘膦(抗草甘膦大豆,英語:Roundup Ready soybean, PRS)轉基因作物(黃豆、棉花、油菜及玉米),使農民能夠殺死雜草而不會殺死他們的莊稼。
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Adinazolam (marketed under the brand name Deracyn) is a tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was developed by Jackson B. Hester, who was seeking to enhance the antidepressant properties of alprazolam, which he also developed. Adinazolam was never FDA approved and never made available to the public market; however, it has been sold as a designer drug.
氢化铊(系统名三氢化铊)是一种无机化合物,实验式为TlH3。它还没有批量获得,因此其批量性质仍然未知。但氢化铊分子已从固体气体中分离出来。氢化铊主要用于学术用途。 氢化铊是最简单的铊氢化物。铊是13族金属中最重的一种;13族氢化物的稳定性随周期数的增加而降低。这通常是由于金属价层轨道与氢原子的1s轨道重叠不佳造成的。尽管早期的报告令人鼓舞,但不太可能分离出一种铊氢化物。氢化铊仅在基体分离研究中被观察到;红外光谱是在氢气存在的情况下,用激光烧蚀铊,在气相中得到的。本研究证实了Schwerdtfeger第一原理计算的某些方面,该第一原理计算表明铊和铟氢化物具有相似的稳定性。迄今为止,还没有确认分离铊氢化物络合物。
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Muscarine is a natural product found in Amanita muscaria, Entoloma rhodopolium, and Cannabis sativa with data available.
驱蛔素(Ascaridol)是一个天然存在的双环单萜,属于少见的有机过氧化物类,是藜科植物土荆芥(Dysphania ambrosioides,以前称为Chenopodium ambrosioides)精油的主要成分。
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Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. It has a role as an antineoplastic agent, an antimetabolite, an immunosuppressive agent, a prodrug, a carcinogenic agent, a DNA synthesis inhibitor and a hepatotoxic agent. It is a thiopurine, a C-nitro compound, a member of imidazoles and an aryl sulfide.
星形孢菌素(英語:Staurosporine,缩写STS,也译为星孢菌素、十字孢碱,开发代号AM-2282)是一种天然的吲哚咔唑,分子式C28H26N4O5,1977年由日本科学家大村智在鏈黴菌屬的Streptomyces staurosporeus(现已归入伦茨菌属,为Lentzea aerocolonigenes的异名)中发现,可用作蛋白激酶特異性抑製劑。
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Epiandrosterone is a natural product found in Homo sapiens with data available.
丁酸丁酯有强烈的、甜润的水果香气,并有香蕉和菠萝似的香韵。在碱性介质中不稳定。在弱酸性介质中尚稳定。不导致变色。
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Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. It is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid, which could make it a candidate drug for use in alcohol aversion therapy. Isovanillin can be used as a precursor in the chemical total synthesis of morphine. The proposed metabolism of isovanillin (and vanillin) in rat has been described in literature, and is part of the WikiPathways machine readable pathway collection.
残杀威(英語:Propoxur,商品名:Baygon,化学式C11H15NO3),是一种氨基甲酸酯类的杀虫剂。
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10-Hydroxydecanoic acid is a natural product found in Trypanosoma brucei with data available.
敌敌畏(英語:Dichlorvos,簡稱DDVP)属于有机磷酸酯类化合物,分子式 C 4 H 7 Cl 2 O 4 P ,是一种常用的环境卫生杀虫剂。敌敌畏自1961年以来一直是可商购的,但因其在城市水道中的流行性以及其毒性远远超出昆虫的影响而引起争议。敌敌畏自1998年起在欧盟被禁用。
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Acetosyringone is a member of the class of acetophenones that is 1-phenylethanone substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5. It has a role as a non-steroidal anti-inflammatory drug, an anti-asthmatic drug, a non-narcotic analgesic, a peripheral nervous system drug and a plant metabolite. It is a member of acetophenones, a dimethoxybenzene and a member of phenols.
愈创木酚(英語:Guaiacol)是一种天然有机物,分子式为 C6H4(OH)(OCH3)。这种无色芳香油状化合物是木馏油的主要成分,可从愈创木树脂、松油等制取。常见的愈创木酚因暴露在空气中或光照下而呈现深色。由于木质素的分解,木柴燃烧时产生的烟雾中含有愈创木酚。许多食物因含有愈创木酚而具有特殊气味,例如烘焙咖啡豆。熏制食物的特殊风味主要属愈创木酚与丁香酚的作用。愈创木酚遇三氯化铁变为蓝色。
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Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. Common side effects include abdominal bloating and cramps. A potential for electrolyte problems as a result of the diarrhea it produces. No evidence of harm to the fetus has been found when used during pregnancy. It is generally regarded as safe during breastfeeding. It is classified as an osmotic laxative. Lactulose was first made in 1929, and has been used medically since the 1950s. Lactulose is made from the milk sugar lactose, which is composed of two simple sugars, galactose and glucose. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2021, it was the 265th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
氟乙酸(英語:Fluoroacetic acid)是一种分子式为CH2FCOOH的化合物。其钠盐,氟乙酸钠被作为杀虫剂。
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Anatabine is a member of bipyridines.
新烟草碱(英語:Anatabine)又称去氢毒藜碱,是一种存在于茄科植物中的微量生物碱。商用烟草中一般含有2-4%(干重)的生物碱,其中尼古丁占据其中90%,剩余10%则包括新烟草碱、降烟碱和假木贼碱(新烟碱)等微量生物碱,这类生物碱是茄科植物用于防御害虫而产生。 新烟草碱在体内外可抑制STAT3蛋白磷酸化,并产生抗炎活性。同时似乎对烟碱型乙酰胆碱受体有活性作用。
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Tridecane is a straight chain alkane containing 13 carbon atoms. It forms a component of the essential oils isolated from plants such as Abelmoschus esculentus. It has a role as a plant metabolite and a volatile oil component.
1,2-二溴乙烷,化學式為BrCH2CH2Br,是一種化合物。它是帶香氣而無色的液體,當其濃度達到10ppm時則可察其存在。其主要來源是人工合成,但大海中亦有微量可能由藻類及海帶製造的1,2-二溴乙烷存在。這亦是一種廣泛使用而又有時帶爭議性的燻蒸劑。
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Mecamylamine is a primary aliphatic amine.
倍他米松(英語:Betamethasone)是一種類固醇藥物,用於治療多種疾病,包括類風濕性關節炎和全身性紅斑狼瘡等風濕性疾病、皮膚炎和乾癬等皮膚病、氣喘和血管性水腫等過敏性疾病、促進早產嬰兒肺部發育、克隆氏症、白血病等癌症,以及與氟氫可的松聯合使用以治療腎上腺功能不全等。給藥方式有口服、肌肉注射或在皮膚上塗抹(通常有霜劑、乳液或液體形式)。 使用此藥物後嚴重的副作用有感染風險增加、肌肉無力、嚴重過敏反應和思覺失調。長期使用可能會導致腎上腺功能不全。長期使用後突然停藥可能會有嚴重性後果。使用霜劑通常會導致毛髮增長和皮膚不適。倍他米松屬於糖皮質素類藥物。它是地塞米松的立體異構體,這兩種化合物僅在16位甲基的空間構型上有所不同(參見類固醇#命名法)。
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Pinane describes a pair of isomeric hydrocarbons. The isomers, actually diastereomers, are both chiral. They are the cis and trans isomers arising from the hydrogenation of the terpenes pinene. Both isomers undergo reaction with air (autoxidation) to give 2-pinane hydroperoxides. Partial reduction of these isomers gives 2-pinanol.
硝基甲烷(化学式:CH3NO2)是最简单的有机硝基化合物。室温下为无色油状有微弱芳香气味的透明液体,有较大的极性,可燃,有毒,具爆炸性。可作燃料。它可以和乙醇、丙酮、乙醚混溶,是一种良好的溶剂和萃取剂。同时由于硝基α-氢具有较强的活性,故硝基甲烷也是化工和有机合成中的常见原料,用于制取药物、杀虫剂、炸药、染料和纤维等。
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Ethambutol is an ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. It has a role as an antitubercular agent, an environmental contaminant and a xenobiotic. It is a member of ethanolamines and an ethylenediamine derivative.
麴酸(C6H6O4;學名5-羥基-2-(羥甲基)-4-吡喃酮),亦作曲酸或鞠酸,是一種化學螯劑,有多種真菌會分泌,特別是米麴菌(Aspergillus oryzae)。
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1-Octen-3-yl acetate is a carboxylic ester.
1-辛烯-3-醇乙酸酯是一种有机化合物,化学式为C10H18O2,也称为乙酸蘑菇酯,是1-辛烯-3-醇和乙酸形成的酯,可由酯化反应制得。它可以以两种对映异构体的形式存在,作为外消旋体得到。它是薰衣草油的成分。
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Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water (one part bromoform in 800 parts water) and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils.
伊波加因(英語:Ibogaine,也译为伊博格碱,或称为:12-甲氧基伊波加明,12-methoxyibogamine)是一种含氮有机化合物,化学式C20H26N2O,是夾竹桃科植物(如Tabernanthe iboga、Voacanga africana和Tabernaemontana undulata)中提取的活性生物鹼,1956年实现全合成。
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Hypotaurine is an aminosulfinic acid comprising ethylamine having the sulfo group at the 2-position. It has a role as a metabolite, a human metabolite and a mouse metabolite. It is a conjugate acid of a hypotaurine(1-). It is a tautomer of a hypotaurine zwitterion.
卡馬西平 (INN:carbamazepine,CBZ),常见商品名 Tegretol(得理多),是一種治療癲癇和神經性疼痛的抗癲癇藥。它可作為輔助藥物,與其他藥物一起治療思覺失調,並用作治療雙相情緒障礙症的二線藥物。卡馬西平對於局部性和全身性癲癇發作的作用似乎與苯妥英和丙戊酸一樣有效。它對於失神癲癇發作或肌陣攣發作無治療效果。 卡馬西平於1953年由瑞士化學家Walter Schindler發現。於1962年首次被核准在瑞士用於治療癲癇。
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Calcium peroxide or calcium dioxide is the inorganic compound with the formula CaO2. It is the peroxide (O22−) salt of Ca2+. Commercial samples can be yellowish, but the pure compound is white. It is almost insoluble in water.
硝基环己烷是一种有机化合物,化学式为C6H11NO2。 硝基环己烷可由二氧化氮(或硝酸)和环己烷反应制得。次氟酸-乙腈氧化叠氮环己烷或环己胺也能得到硝基环己烷。它可以被硼氢化钠还原为环己胺。它和甲醛反应,可以得到1-硝基-1-羟甲基环己烷。它在碱性条件下和高锰酸钾反应,可以得到环己酮。
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Carbendazim is a member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. It has a role as an antinematodal drug, a metabolite, a microtubule-destabilising agent and an antifungal agrochemical. It is a carbamate ester, a member of benzimidazoles, a benzimidazole fungicide and a benzimidazolylcarbamate fungicide. It is functionally related to a 2-aminobenzimidazole.
头孢替唑(英语:Ceftezole或Ceftezol)是一种半合成的第一代头孢菌素抗生素。 头孢替唑与细菌细胞壁内膜上的青霉素结合蛋白(PBP)结合并使其失活。PBP是参与细菌细胞壁组装的最终阶段以及在生长和分裂过程中重塑细胞壁的酶。PBP的失活会干扰细菌细胞壁强度和刚性所必需的肽聚糖链细菌细胞壁的交联。这会导致细菌细胞壁减弱并导致细胞溶解。 头孢替唑具有(1,3,4-噻二唑-2-基硫基)甲基和[2-(1H-四唑-1-基)乙酰氨基侧基,分别位于3位和7位。它是一种头孢菌素,属于噻二唑类药物。
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Kalafungin is a substance discovered in the 1960s and found to act as a broad-spectrum antibiotic in vitro. It was isolated from a strain of the bacterium Streptomyces tanashiensis. It is not known to be marketed anywhere in the world.
硫代水杨酸是一种有机硫化合物,是水杨酸的羟基氧被硫取代的产物,化学式为C6H4(SH)(CO2H)。它是黄色固体,微溶于水、乙醇、乙醚、烷烃,可溶于二甲基亚砜。它可以由邻氨基苯甲酸经重氮化、硫化、还原得到。
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Methyl methacrylate is an enoate ester having methacrylic acid as the carboxylic acid component and methanol as the alcohol component. It has a role as an allergen and a polymerisation monomer. It is an enoate ester and a methyl ester. It is functionally related to a methacrylic acid.
2-辛酮是一种有机化合物,化学式为CH3C(O)C6H13,它是无色挥发性液体,用于香料工业。它是由丙酮和戊醛缩合,再经氢化得到;或通过1-辛烯的选择性氧化制得。它是许多熟食中常见的微量成分。
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Chrysanthemic acid is a monocarboxylic acid that is cyclopropanecarboxylic acid substituted by two methyl groups at position 2 and a 2-methylprop-1-en-1-yl group at position 3. It has a role as a plant metabolite. It is a member of cyclopropanes and a monocarboxylic acid. It is functionally related to a cyclopropanecarboxylic acid.
菊酸(chrysanthemic acid)是和各种天然或合成杀虫剂有关的有机化合物的一种。该物质与除虫菊酯、拟除虫菊酯有关,许多合成的拟除虫菊酯,都是菊酸酯。
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Hexamethyldisiloxane (HMDSO or MM) is an organosilicon compound with the formula O[Si(CH3)3]2. This volatile colourless liquid is used as a solvent and as a reagent in organic synthesis. It is prepared by the hydrolysis of trimethylsilyl chloride. The molecule is the protypical disiloxane and resembles a subunit of polydimethylsiloxane.
正己胺(英語:n-hexylamine,又称1-己胺)是化学式为CH3CH2CH2CH2CH2CH2NH2的烷基胺化合物,常温常压下为无色液体,可溶于大部分有机溶剂。
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1-Tetradecanol, or commonly myristyl alcohol (from Myristica fragrans – the nutmeg plant), is a straight-chain saturated fatty alcohol, with the molecular formula CH3(CH2)12CH2OH. It is a white waxy solid that is practically insoluble in water, soluble in diethyl ether, and slightly soluble in ethanol.
1-十四烷醇是一種直鏈飽和脂肪醇,份子式為C14H30O。它為白色結晶固體,實際上不溶於水,但溶於乙醚,微溶於乙醇。
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Tribenuron is an N-sulfonylurea that is N-(2-carboxybenzenesulfonyl)urea bearing additional methyl and 4-methoxy-6-methyl-1,3,5-triazin-2-yl substituents at position N3. A foliar acting, post-emergence herbicide used to control broad-leaved weeds in cereals, normally used as the methyl variant. It has a role as a herbicide. It is a N-sulfonylurea, a methoxy-1,3,5-triazine and a member of benzoic acids.
甲锗烷是锗烷(GenH2n+2)中最简单的一种,分子式为GeH4。和同族的甲烷、甲硅烷一样,甲锗烷也是正四面体结构。甲锗烷在空气中燃烧生成二氧化锗和水。
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Pregnenolone sulfate is a steroid sulfate. It has a role as an EC 2.7.1.33 (pantothenate kinase) inhibitor and a human metabolite. It is functionally related to a pregnenolone. It is a conjugate acid of a pregnenolone sulfate(1-).
硫酸孕烯醇酮(英語:Pregnenolone sulfate,缩写PREG-S、PREGS,也可称为孕-5-烯-3β-硫酸酯-20-酮,pregn-5-en-3β-ol-20-one 3β-sulfate)是一种内源性的神经甾体,合成自孕烯醇酮,常作为益智藥和抗抑郁药。
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Berberine is an organic heteropentacyclic compound, an alkaloid antibiotic, a botanical anti-fungal agent and a berberine alkaloid. It has a role as an antilipemic drug, a hypoglycemic agent, an antioxidant, a potassium channel blocker, an antineoplastic agent, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor, an EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor, an EC 1.21.3.3 (reticuline oxidase) inhibitor, an EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor, an EC 3.1.1.4 (phospholipase A2) inhibitor, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor, an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 2.7.11.10 (IkappaB kinase) inhibitor, an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor, a geroprotector and a metabolite.
頭孢唑林 (英語:Cefazolin,也可拼寫為cephazolin,或是cefazoline),是種第一代頭孢菌素類抗生素,用於治療多種病原細菌感染。特別是它可用於治療蜂窩性組織炎、泌尿道感染、肺炎、感染性心內膜炎、敗血性關節炎和急性膽管炎。它也在分娩前後和手術前使用,以預防B型鏈球菌感染。此藥物通常透過肌肉注射或是靜脈注射方式給藥。
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Dihydrouracil is a natural product found in Daphnia pulex, Arabidopsis thaliana, and other organisms with data available.
肉豆蔻醚(英語:Myristicin)是一种有机化合物,化学式为C11H12O3,存在于肉豆蔻等许多草药和香料中。
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Trichloroacetonitrile is an organic compound with the formula CCl3CN. It is a colourless liquid, although commercial samples often are brownish. It is used commercially as a precursor to the fungicide etridiazole. It is prepared by dehydration of trichloroacetamide. As a bifunctional compound, trichloroacetonitrile can react at both the trichloromethyl and the nitrile group. The electron-withdrawing effect of the trichloromethyl group activates the nitrile group for nucleophilic additions. The high reactivity makes trichloroacetonitrile a versatile reagent, but also causes its susceptibility towards hydrolysis.
栀子酸(英語:Geniposidic acid,缩写GPA)又称京尼平苷酸,是一种天然的化合物,分子式C16H22O10,属于一种环烯醚萜葡萄糖苷,存在于杜仲(Eucommia ulmoides)、栀子花(Gardenia jasminoides)等植物中 。
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Duvoglustat is an optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. It has a role as an EC 3.2.1.20 (alpha-glucosidase) inhibitor, an anti-HIV agent, an anti-obesity agent, a bacterial metabolite, a hypoglycemic agent, a hepatoprotective agent and a plant metabolite. It is a 2-(hydroxymethyl)piperidine-3,4,5-triol and a piperidine alkaloid.
穀胱甘肽(英語:Glutathione,簡稱:GSH),又称麸胱甘肽或麩氨基硫,屬於三肽,由穀氨酸、半胱氨酸及甘氨酸所構成,其中第一个肽键与普通的肽键不同,是由穀氨酸的γ-羧基与半胱氨酸的氨基组成的,在分子中半胱氨酸巯基是该化合物的主要功能基团。谷胱甘肽是植物、动物、真菌和一些细菌和古菌中的一种抗氧化剂。谷胱甘肽能够防止活性氧、自由基、过氧化物、脂质过氧化物和重金属等来源对重要细胞成分造成的损害。 作为動物細胞中的抗氧化剂,存在於充滿水的細胞內部,可以保護DNA免於氧化。穀胱甘肽以兩種型態存在於人體,一是还原型態、另一是氧化型態。菠菜含有穀胱甘肽。
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Diphenyl ether is an aromatic ether in which the oxygen is attached to two phenyl substituents. It has been found in muscat grapes and vanilla. It has a role as a plant metabolite.
氧宝龙环戊丙酸酯(英語:Oxabolone cipionate或oxabolone cypionate,开发代号:FI-5852,商品名有:Steranabol Depo、Steranabol Ritardo,化学名:4-羟基-19-去甲睾酮-17β-环戊丙酸酯,4-hydroxy-19-nortestosterone 17β-cypionate,或雌-4-烯-4,17β-二醇-3-酮-17β-环戊丙酸酯,estr-4-en-4,17β-diol-3-one 17β-cypionate)是一种有机化合物,分子式C26H38O4,可看作氧宝龙17β位置的3-环戊基丙酸酯,属于雄激素酯类同化類固醇。
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Quinolinic acid is a pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan. It has a role as a NMDA receptor agonist, a human metabolite, a mouse metabolite and an Escherichia coli metabolite. It is a conjugate acid of a quinolinate(1-) and a quinolinate.
野靛碱(英語:Cytisine,或 baptitoxine、cytisinicline、sophorine),又称金雀花碱,是一种生物鹼,化学式为C11H14N2O,存在于毒豆属(Laburnum)、金雀儿属(Cytisus)等豆科植物中,常用于戒烟。
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Hydralazine is the 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent. It has a role as an antihypertensive agent and a vasodilator agent. It is a member of phthalazines, an azaarene, an ortho-fused heteroarene and a member of hydrazines.
正十二面体烷(英語:Dodecahedrane),又称十二面烷、正十二面烷,是一个正十二面体形状的碳氢化合物,化学式为C20H20,不存在于自然界中。它的合成首先由俄亥俄州立大学的Leo Paquette于1982年完成,该合成路线被誉为有机合成的经典作品之一。
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Licarbazepine is a dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine. It has a role as a sodium channel blocker, an anticonvulsant and a drug allergen. It is a carboxamide, a dibenzoazepine and a member of ureas. It is functionally related to a carbamazepine.
甲氰菊酯是在农业和家庭中广泛使用的拟除虫菊酯类杀虫剂,为白色晶体,原药带有黄色。它被认为是帕金森病的环境危险因子。 它可以2,2,3,3-四甲基环丙基甲酸和间苯氧基苯甲醛为原料合成得到。
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Setiptiline is a tetracyclic antidepressant that is 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine carrying a methyl group at position 2. Its maleate salt is used for the treatment of depression in Japan. It has a role as an alpha-adrenergic antagonist and a serotonergic antagonist. It is a tetracyclic antidepressant and a tertiary amino compound. It is a conjugate base of a setiptiline(1+).
甲硝唑(英語:metronidazole,MNZ)又稱甲硝噠唑,以商品名咪唑尼達(Flagyl)著稱,是一種抗生素和抗原蟲劑。常單獨或和其他抗生素一起使用,作為治療骨盆腔炎、心內膜炎與細菌性陰道炎的藥物。在對抗麥地那龍線蟲病、梨形鞭毛蟲症、陰道滴蟲和阿米巴病上更有顯著效果。針對首次發病的輕中度困難梭狀芽孢桿菌結腸炎患者,此藥為第一優先藥物。甲硝唑可藉由口服、製成乳膏,或經靜脈注射來進行治療。 常見的副作用包含噁心、口腔金屬味感、失去食慾及頭痛,少數病患可能會癲癇發作或產生藥物過敏。對於懷孕初期的孕婦,不應給予甲硝唑,但若是到了懷孕後期則沒有這個顧忌。特別注意的是,正在哺乳的婦女也不建議使用。 甲硝唑首先在1960年的法國開始被廣泛使用。它名列世界衛生組織基本藥物標準清單中,是基礎醫療上必備的藥物,在世界上大部分國家都能輕易取得。本藥物的價格十分低廉,每顆平均價格介於0.01到0.1美元間。在美國,十天的療程大約需花費26美元,美国食品和药物管理局建议它仅在必要时使用,因为它已被证明在小鼠和大鼠中是致癌的,并且某些微生物可以对其产生抗药性。
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Selenonic acid is a selenium oxoacid.
在有机化学中,硒酸是含有–SeO3H基团的化合物,它可由高锰酸钾氧化相应的亚硒酸制得,或通过高锰酸钾和氯气氧化二硒醚得到。它的盐类是已知的。 有机硒酸是一种强酸,具有强氧化性,受热可以分解。
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Valerophenone is a natural product found in Ligusticum striatum, Apium graveolens, and other organisms with data available.
山梨醇(英語:Sorbitol),又稱葡萄糖醇、己六醇,是一种能缓慢代谢的糖醇。分子式為C6H14O6,與單糖的結構相似,可通过还原葡萄糖上的醛基为羟基来获得。
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Fulvene is an organic cyclic compound that consists of cyclopentadiene bearing a methylene substituent. The parent of the class of fulvenes.
异丁酸甲酯是一种具示性式(CH3)2CHC(O)OCH3之有机化合物 。其為異丁酸之甲醇酯,在常溫常壓下為無色液體,常被用為溶剂。
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Budipine (brand name Parkinsan) is an antiparkinson agent marketed for the treatment of Parkinson's disease. While its exact mechanism of action is not well characterized, it is believed to be an NMDA receptor antagonist, but also promoting the synthesis of dopamine. Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment. It is an hERG blocker and can produce long QT syndrome as a side effect. Analogues include prodipine and medipine.
叔丁哌苯(英語:Budipine,也译为布地平)商品名Parkinsan,分子式C21H27N,是一种帕金森氏症治疗药物,其作用机制尚未解明。
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Chloroacetaldehyde is an organic compound with the formula ClCH2CHO. Like some related compounds, it is highly electrophilic reagent and a potentially dangerous alkylating agent. The compound is not normally encountered in the anhydrous form, but rather as the hemiacetal (ClCH2CH(OH))2O. Chloroacetaldehyde is a metabolite of the antineoplastic ifosfamide and believed to be responsible for some of the toxicity observed with ifosfamide.
没食子酸乙酯(英語:Ethyl gallate)是一种酚酸类化合物,是没食子酸与乙醇形成的酯,可作为食品添加剂,E编码E313,存在于千果榄仁(学名:Terminalia myriocarpa)、诃子(学名:Terminalia chebula)等植物中。
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Dimethylamine is a secondary aliphatic amine where both N-substituents are methyl. It has a role as a metabolite. It is a secondary aliphatic amine and a member of methylamines. It is a conjugate base of a dimethylaminium.
2,2,4-三甲基戊烷是辛烷的一種异构体,俗称异辛烷(isooctane)。异辛烷在内燃机的汽缸里燃烧时抗震性较好,是汽油抗爆震度的一個標準,其辛烷值定為100(正庚烷之辛烷值定為0)。是优良的发动机燃料,但由于其价格昂贵,一般只用于军用、赛用和民航燃料使用,汽车工业上不采用異辛烷作为抗爆剂,而通常使用成本更低,但效果稍逊的甲基第三丁基醚代替。
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Oxypertine is an organic molecular entity.
安乃近(英文名 Metamizole Sodium;Metamizole、dipyrone、Sulpyrine),一种解热镇痛药,1920年被德国霍伊斯特公司公司合成,1922年开始批量生产。
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Pentane is a natural product found in Calendula officinalis and Allium ampeloprasum with data available.
该化合物自然发生的水合形式有三个矿物种类:一水、二水和三水合物。自然界中主要存在草酸钙石(一水)、水草酸钙石(二水)和较少见的碳氧钙石(caoxite,三水)三种草酸钙的矿物。三水合物于130 °C时转化为一水合物,一水合物于200 °C时完全脱水为无水盐,并于430 °C分解。
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Diprenorphine is a morphinane alkaloid.
氯氧磷(英語:Chlorethoxyfos)是一种有机磷乙酰胆碱酯酶抑制剂,常用作杀虫剂。 Template:Cholinergics
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Enterodiol is an organic compound with the formula [HOC6H4CH2CH(CH2OH)]2. It is formed by the action of intestinal bacteria on lignan precursors. As such it is sometimes classified as a enterolignan or mammalian lignan. Elevated levels of enterodiol in urine are attributed consumption of tea and other lignan-rich foods.
己二酸二甲酯(英語:Dimethyl adipate)是一种己二酸酯,化学式(CH2CH2CO2CH3)2,常温常压下为无色油状液体,和尼龙的生产有关,常用作塑化剂。
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Phenethyl acetate is the ester resulting from the condensation of acetic acid and phenethyl alcohol. Like many esters, it is found in a range of fruits and biological products. It is a colorless liquid with a rose and honey scent and a raspberry-like taste.
哌啶(Piperidine),又称六氢吡啶、氮杂环己烷,是一个杂环化合物,分子式为(CH2)5NH。它是一个仲胺,可看作环己烷一个碳被氮替代后形成的化合物,即氮杂环己烷。室温下为无色发烟液体,有类似氨、胡椒和人類精液的刺激性气味,广泛应用在有机合成,尤其是药物合成中。亦可用于DNA测序。
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Carbofuran is a carbamate ester and a member of 1-benzofurans. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a carbamate insecticide, an EC 3.1.1.8 (cholinesterase) inhibitor, an acaricide, an agrochemical, an avicide and a nematicide.
二十四烷(Tetracosane,tetrakosane)是化學式為CH3(CH2)22CH3的烷烴。和其他的烷烴相同,它的名字是由它的碳原子的數量(24)而來的,而它的英文名字就是由24的希臘文名稱而來的。它有14,490,245個同分異構體. 正二十四烷能在捷克斯洛伐克,西伯利亞的下通古斯河和東摩拉維亞近Konma的Bucnik採石場的Evenki地區的evenkite礦石裏找到。Evenkite的薄片無色,而礦石是熒光橙黃色。
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2-Aminothiophenol is an organosulfur compound with the formula C6H4(SH)(NH2). It is a colorless oily solid, although impure samples can be deeply colored. It is soluble in organic solvents and in basic water. 2-Aminothiophenol is a precursor to benzothiazoles, some of which are bioactive or are commercial dyes. Isomers of aminothiophenols include 3-aminothiophenol and 4-aminothiophenol. 2-Aminothiophenol can prepared in two steps, starting with the reaction of aniline with carbon disulfide followed by hydrolysis of the resulting mercaptobenzothiazole. It can also obtained by zinc reduction of 2-nitrobenzenesulfonyl chloride.
苝(bèi)(英語:Perylene),或稱二萘嵌苯,是一种多环芳香烃,化学式为C20H12,呈棕色固体。其衍生物可能致癌,被认为是一种有害污染物。在细胞化学中,苝被用作荧光脂质探针。这是一类Rylene染料的母体化合物。
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Cyclohexanol is a natural product found in Punica granatum, Gossypium hirsutum, and Mangifera indica with data available.
氯黴素於1947年 由大衛·戈特利布從南美洲委內瑞拉的土壤內的委內瑞拉鏈黴菌分離發現,是世界上首種完全由合成方法大量製造的廣譜抗生素。它被列入世界衛生組織基本藥物標準清單,是基層衛生系統中最重要的藥物之一。氯黴素為一種學名藥。全球多處地區氯霉素的靜脈注射價格大約一劑0.40至1.90美元,因價錢低廉的關係,現時仍然盛行於一些低收入國家,但在其他西方國家經已甚少使用,這是由於它的副作用的關係。在美國,氯黴素非常昂貴(41.47美元)全球抗生素抗藥性問題使得氯黴素仍被考慮使用。。
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