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EleutherAI 808

[ { "aid": 1, "atext": "Only ferrous salts should be used orally." }, { "aid": 2, "atext": "Only ferric salts should be used orally." }, { "aid": 3, "atext": "Orally, the most appropriate form is the iron-dextran complex." }, { "aid": 4, "atext": "Orally, the treatment should last a maximum of fifteen days." }, { "aid": 5, "atext": "Only ferrous salts should be used parenterally." } ]

[ { "aid": 1, "atext": "Less than 10%" }, { "aid": 2, "atext": "Between 10% and 20%." }, { "aid": 3, "atext": "More than 90%" }, { "aid": 4, "atext": "Between 20% and 40%." }, { "aid": 5, "atext": "50%" } ]

[ { "aid": 1, "atext": "They cause hypotension in individuals with normal blood pressure." }, { "aid": 2, "atext": "They increase the atrio-ventricular conduction velocity." }, { "aid": 3, "atext": "They cause negative inotropism." }, { "aid": 4, "atext": "They provoke a positive chronotropic effect." }, { "aid": 5, "atext": "They increase the secretion of renin." } ]

[ { "aid": 1, "atext": "Increases its permeability in case of inflammation." }, { "aid": 2, "atext": "It is homogeneous throughout the encephalon." }, { "aid": 3, "atext": "It is traversed freely by fat-soluble drugs." }, { "aid": 4, "atext": "It is maximum in the chemoreceptor area of ​​the trigger." }, { "aid": 5, "atext": "Decreases its permeability in case of inflammation." } ]

[ { "aid": 1, "atext": "Methylcellulose" }, { "aid": 2, "atext": "Glycerin." }, { "aid": 3, "atext": "Loperamide." }, { "aid": 4, "atext": "Methylnaltrexone" }, { "aid": 5, "atext": "Racecadotril." } ]

[ { "aid": 1, "atext": "It is structurally related to thienopyridines." }, { "aid": 2, "atext": "It inhibits adenyl cyclase, and therefore increases cAMP levels." }, { "aid": 3, "atext": "It has a low index of myelotoxicity in relation to ticlopidine." }, { "aid": 4, "atext": "It has a longer action in relation to ticlopidine." }, { "aid": 5, "atext": "In case of surgical intervention, it is recommended to interrupt the treatment at least one week in advance." } ]

[ { "aid": 1, "atext": "Angioedema" }, { "aid": 2, "atext": "Pulmonary hypertension in neonates." }, { "aid": 3, "atext": "Diabetic nephropathy" }, { "aid": 4, "atext": "Benign prostatic hyperplasia." }, { "aid": 5, "atext": "Narrow angle glaucoma." } ]

[ { "aid": 1, "atext": "A loop diuretic or high ceiling." }, { "aid": 2, "atext": "A thiazide." }, { "aid": 3, "atext": "An osmotic diuretic." }, { "aid": 4, "atext": "A potassium-sparing diuretic." }, { "aid": 5, "atext": "A diuretic carbonic anhydrase inhibitor." } ]

[ { "aid": 1, "atext": "5-HT1." }, { "aid": 2, "atext": "Adrenergic 1 and 2." }, { "aid": 3, "atext": "Histaminergic H1." }, { "aid": 4, "atext": "GABA" }, { "aid": 5, "atext": "Muscarinic cholinergic" } ]

[ { "aid": 1, "atext": "They can be obtained by fermentation of pure Claviceps purpurea cultures and derived from phenylalanine and isoprene obtained by the mevalonic acid route (MVA)." }, { "aid": 2, "atext": "They can be obtained by fermentation of pure cultures of Claviceps purpurea and derived from tyrosine and isoprene obtained by the DOXP route." }, { "aid": 3, "atext": "They can be obtained by fermentation of pure cultures of Claviceps purpurea and derived from tryptophan and isoprene obtained by the route of mevalonic acid (MVA)." }, { "aid": 4, "atext": "They can be obtained by rye infection with Claviceps purpurea spores and derived from tryptophan and isoprene obtained by the DOXP route." }, { "aid": 5, "atext": "They can be obtained by wheat infection with Claviceps purpurea spores and derived from tyrosine and isoprene obtained by the mevalonic acid (MVA) route." } ]

[ { "aid": 1, "atext": "Indolemonoterpenic alkaloids, dimeric with antiarrhythmic activity." }, { "aid": 2, "atext": "Alkaloids derived from phenylalanine, monomeric with arrhythmic activity." }, { "aid": 3, "atext": "Indolemonoterpenic alkaloids, dimeric with antitumor activity." }, { "aid": 4, "atext": "Indolemonoterpenic, monomeric alkaloids with antitumor activity." }, { "aid": 5, "atext": "Alkaloids derived from phenylalanine, dimeric and with antitumor activity." } ]

[ { "aid": 1, "atext": "Hypothyroidism" }, { "aid": 2, "atext": "Neurosis." }, { "aid": 3, "atext": "Psychosis." }, { "aid": 4, "atext": "Multiple myeloma." }, { "aid": 5, "atext": "Schizophrenia." } ]

[ { "aid": 1, "atext": "Absorption and elimination." }, { "aid": 2, "atext": "Distribution-return and elimination." }, { "aid": 3, "atext": "Absorption and distribution-return." }, { "aid": 4, "atext": "Metabolism and excretion." }, { "aid": 5, "atext": "Distribution-return." } ]

[ { "aid": 1, "atext": "The fraction or percentage of drug dose that after being administered in a certain pharmaceutical form has unchanged access to the biophase compared to an intravenous preparation thereof." }, { "aid": 2, "atext": "The fraction or percentage of drug dose that after being administered in a certain pharmaceutical form has unaltered access to the systemic circulation compared to a standard preparation thereof." }, { "aid": 3, "atext": "The fraction or percentage of drug dose that after being administered in a certain pharmaceutical form has unaltered access to the systemic circulation compared to an intravenous preparation thereof." }, { "aid": 4, "atext": "That 100% of the dose of drug administered in a certain pharmaceutical form has unaltered access to the general circulation." }, { "aid": 5, "atext": "The fraction or percentage of drug dose that after being administered in a certain pharmaceutical form has unaltered access to the place of absorption in comparison with a standard preparation thereof." } ]

[ { "aid": 1, "atext": "Your representative is cefepima." }, { "aid": 2, "atext": "They should be avoided in Enterobacter infections." }, { "aid": 3, "atext": "They are not useful in meningitis secondary to pneumococcus." }, { "aid": 4, "atext": "They are of choice in meningitis due to Listeria." }, { "aid": 5, "atext": "They should never be associated with an aminoglycoside." } ]

[ { "aid": 1, "atext": "Theophylline" }, { "aid": 2, "atext": "Digoxin" }, { "aid": 3, "atext": "Ampicillin" }, { "aid": 4, "atext": "Thioridazine." }, { "aid": 5, "atext": "Ciclosporin" } ]

[ { "aid": 1, "atext": "The ratio between the maintenance dose and the dosage interval." }, { "aid": 2, "atext": "The product of the maintenance dose by the rate constant of absorption." }, { "aid": 3, "atext": "The quotient between the dosing interval and the absorption rate constant." }, { "aid": 4, "atext": "The product of the maintenance dose by the accumulation factor." }, { "aid": 5, "atext": "The product of the dosing rate by the absorption rate constant." } ]

[ { "aid": 1, "atext": "The apparent volume of the distribution decreases with time from a maximum value to a value that becomes constant." }, { "aid": 2, "atext": "The apparent volume of distribution as a function of the area is greater than the apparent volume of distribution in the steady state of equilibrium." }, { "aid": 3, "atext": "The apparent volume of distribution is constant over time." }, { "aid": 4, "atext": "The so-called initial distribution volume is greater than the apparent volume of distribution in phase ." }, { "aid": 5, "atext": "The apparent volume of distribution calculated by extrapolation is less than the apparent volume of distribution in the steady state equilibrium." } ]

[ { "aid": 1, "atext": "Less than the unsolvated form of the drug." }, { "aid": 2, "atext": "Limiting step of the disintegration of the tablets in which the drug is formulated." }, { "aid": 3, "atext": "Greater than the unsolvated form of the drug." }, { "aid": 4, "atext": "Limiting factor of the distribution of the drug to the aqueous sectors of the organism." }, { "aid": 5, "atext": "Same as the unsolvated form of the drug." } ]

[ { "aid": 1, "atext": "mg-1." }, { "aid": 2, "atext": "h-1." }, { "aid": 3, "atext": "mg / h." }, { "aid": 4, "atext": "g X h / mL." }, { "aid": 5, "atext": "mL / h." } ]

[ { "aid": 1, "atext": "Glucuronidation." }, { "aid": 2, "atext": "Desamination" }, { "aid": 3, "atext": "Methylation" }, { "aid": 4, "atext": "Conjugation with glycine." }, { "aid": 5, "atext": "Acetylation" } ]

[ { "aid": 1, "atext": "The concentration reached in steady state of equilibrium depends exclusively on the clearance." }, { "aid": 2, "atext": "The time necessary to reach the steady state of equilibrium depends on the volume of distribution." }, { "aid": 3, "atext": "The concentration reached in a steady state depends exclusively on the elimination half-life." }, { "aid": 4, "atext": "The concentration achieved in the steady state equilibrium depends on the clearance and the infusion rate." }, { "aid": 5, "atext": "The time required to reach the steady state of equilibrium depends on the clearance." } ]

[ { "aid": 1, "atext": "Clearance of creatinine in the uremic patient (CLcrIR) and in individuals with normal renal function (CLcrFRN)." }, { "aid": 2, "atext": "The renal clearance of the drug in patients with normal renal function (CLrFRN), CLcrIR and CLcrFRN." }, { "aid": 3, "atext": "The fraction of drug excreted in unaltered form in the urine (fr), the dose administered (D), CLrFRN, CLcrIR and CLcrFRN." }, { "aid": 4, "atext": "fr, CLcrIR and CLcrFRN and the plasma clearance of the drug in patients with normal renal function" }, { "aid": 5, "atext": "fr, CLrFRN, CLcrIR, CLcrFRN and D." } ]

[ { "aid": 1, "atext": "4.0 and 360 L / h." }, { "aid": 2, "atext": "0.5 and 45 L / h." }, { "aid": 3, "atext": "1.0 and 90 L / h." }, { "aid": 4, "atext": "0.25 and 20 L / h." }, { "aid": 5, "atext": "2.0 and 180 L / h." } ]

[ { "aid": 1, "atext": "A potent enzyme inducer of cytochrome P450 (CYP3A4)." }, { "aid": 2, "atext": "A potent enzyme inhibitor of cytochrome P450 (CYP3A4)." }, { "aid": 3, "atext": "A promoter of the absorption of drugs administered orally." }, { "aid": 4, "atext": "An advisable food to increase the bioavailability of drugs of acidic nature." }, { "aid": 5, "atext": "A food without consequence in the kinetics of disposal of drugs eliminated by metabolism in which cytochrome P450 is involved." } ]

[ { "aid": 1, "atext": "It is significantly influenced by the hepatic blood flow." }, { "aid": 2, "atext": "It is significantly influenced by changes in the degree of plasma protein binding." }, { "aid": 3, "atext": "It is significantly influenced both by hepatic blood flow and by changes in the degree of plasma protein binding." }, { "aid": 4, "atext": "It will not be influenced by the hepatic blood flow or by changes in the degree of binding to plasma proteins." }, { "aid": 5, "atext": "It will depend on the absolute bioavailability of the drug." } ]

[ { "aid": 1, "atext": "Chymotrypsin" }, { "aid": 2, "atext": "Cytochrome c." }, { "aid": 3, "atext": "Alpha-keratin" }, { "aid": 4, "atext": "Lysozyme" }, { "aid": 5, "atext": "Ribonuclease." } ]

[ { "aid": 1, "atext": "Pyruvate dehydrogenase (synthesis of acetyl CoA)." }, { "aid": 2, "atext": "Alpha-ketoglutarate dehydrogenase (citric acid cycle)." }, { "aid": 3, "atext": "Transketolase (pentose phosphate pathway)." }, { "aid": 4, "atext": "Transaldolase (pentose phosphate route)." }, { "aid": 5, "atext": "Pyruvate decarboxylase (ethanolic fermentation)." } ]

[ { "aid": 1, "atext": "Lactoferrin protects against infections due to its ability to bind iron." }, { "aid": 2, "atext": "The casein peptides have antimicrobial and immunostimulant activity." }, { "aid": 3, "atext": "Cytokines modulate the immune system in childhood." }, { "aid": 4, "atext": "Complex oligosaccharides can be false receptors for bacteria in the intestine." }, { "aid": 5, "atext": "Lysozyme degrades the cell walls of gram-negative organisms." } ]

[ { "aid": 1, "atext": "Isocitrate dehydrogenase." }, { "aid": 2, "atext": "Glucose 6-phosphate dehydrogenase." }, { "aid": 3, "atext": "Succinate dehydrogenase." }, { "aid": 4, "atext": "Malate dehydrogenase." }, { "aid": 5, "atext": "Lactate dehydrogenase." } ]

[ { "aid": 1, "atext": "It must be balanced (25% soluble and 75% insoluble, approximately)." }, { "aid": 2, "atext": "The higher the consumption of fiber, the lower the water intake." }, { "aid": 3, "atext": "The products made with refined seeds have a high fiber content." }, { "aid": 4, "atext": "Legumes are a poor source of fiber." }, { "aid": 5, "atext": "In the adult, 10-15 g of fiber are recommended daily." } ]

[ { "aid": 1, "atext": "Hyaluronan" }, { "aid": 2, "atext": "Cellulose." }, { "aid": 3, "atext": "Chitin" }, { "aid": 4, "atext": "Dextran" }, { "aid": 5, "atext": "Glycogen" } ]

[ { "aid": 1, "atext": "Uric acid." }, { "aid": 2, "atext": "Succinate" }, { "aid": 3, "atext": "Ammonia." }, { "aid": 4, "atext": "Urea." }, { "aid": 5, "atext": "Fumarate" } ]

[ { "aid": 1, "atext": "They increase intracellular cholesterol synthesis." }, { "aid": 2, "atext": "They cause a decrease in the number of LDL receptors present on the surface of hepatocytes." }, { "aid": 3, "atext": "They decrease the intracellular synthesis of triacylglycerides." }, { "aid": 4, "atext": "They diminish intracellular cholesterol synthesis and induce the expression of LDL receptors." }, { "aid": 5, "atext": "They increase the synthesis of steroid hormones." } ]

[ { "aid": 1, "atext": "It catalyzes the reversible transformation of pyruvate into acetyl-CoA and vice versa." }, { "aid": 2, "atext": "It catalyzes the irreversible carboxylation of pyruvate into citrate, and with it, its entry into the citric acid cycle." }, { "aid": 3, "atext": "It connects the degradation of carbohydrates, with the synthesis of acetyl-CoA and its entry into the citric acid cycle." }, { "aid": 4, "atext": "It allows the use of acetyl-CoA derived from the degradation of fatty acids for the synthesis of glucose." }, { "aid": 5, "atext": "It is activated in the presence of high concentrations of acetyl-CoA and NADH + H +." } ]

[ { "aid": 1, "atext": "Sterols" }, { "aid": 2, "atext": "Prostaglandins" }, { "aid": 3, "atext": "Phosphoacylglycerides." }, { "aid": 4, "atext": "Arachidonic acid." }, { "aid": 5, "atext": "Glycerophospholipids." } ]

[ { "aid": 1, "atext": "It activates the phosphorylation of glycogen phosphorylase and the degradation of glycogen." }, { "aid": 2, "atext": "It increases the intracellular concentration of cAMP, and therefore, the synthesis of glycogen." }, { "aid": 3, "atext": "It decreases the intracellular concentration of cAMP and the degradation of glycogen." }, { "aid": 4, "atext": "The phosphorylation of glycogen synthase and glycogen synthesis is activated." }, { "aid": 5, "atext": "Increases the intracellular concentration of ATP and glycogenesis." } ]

[ { "aid": 1, "atext": "Ethanol." }, { "aid": 2, "atext": "Oleic acid." }, { "aid": 3, "atext": "Acetyl-CoA." }, { "aid": 4, "atext": "NADPH + H +." }, { "aid": 5, "atext": "Glycerol." } ]

[ { "aid": 1, "atext": "The inhibition of the mitochondrial respiratory chain." }, { "aid": 2, "atext": "The inhibition of protein catabolism." }, { "aid": 3, "atext": "An increase in renal protein catabolism." }, { "aid": 4, "atext": "A failure in the entry of muscle fatty acids into the mitochondria for oxidation." }, { "aid": 5, "atext": "A decrease in hepatic lipogenesis." } ]

[ { "aid": 1, "atext": "Follow a hyperbolic kinetics." }, { "aid": 2, "atext": "It favors the transition from Fe2 + to Fe3 + in the heme group of the protein." }, { "aid": 3, "atext": "Induces the deprotonation of the protein." }, { "aid": 4, "atext": "It is facilitated in the presence of 2,3bisphosphoglycerate." }, { "aid": 5, "atext": "It is carried out through a covalent interaction with Fe3 +." } ]

[ { "aid": 1, "atext": "The systems of transport of fatty acids into the mitochondria." }, { "aid": 2, "atext": "The cytochromes of the mitochondrial electronic transport chain." }, { "aid": 3, "atext": "The enzymes of glycolysis." }, { "aid": 4, "atext": "The dehydrogenase enzymes of the citric acid cycle." }, { "aid": 5, "atext": "The enzymes that catalyze the replication of DNA." } ]

[ { "aid": 1, "atext": "A molecule of an organic nature, necessary for the activity of an enzyme." }, { "aid": 2, "atext": "The inorganic part of an enzyme." }, { "aid": 3, "atext": "A molecule of a protein nature, necessary for the activity of an enzyme." }, { "aid": 4, "atext": "Any molecule of a non-vitamin nature that contributes to increase the activity of an enzyme." }, { "aid": 5, "atext": "An allosteric effect that modifies the spatial configuration of enzymes." } ]

[ { "aid": 1, "atext": "Western blot." }, { "aid": 2, "atext": "Immunoprecipitation of chromatin." }, { "aid": 3, "atext": "Matrix-assisted laser desorption (MALDI)." }, { "aid": 4, "atext": "Fingerprint." }, { "aid": 5, "atext": "Denaturing gel electrophoresis." } ]

[ { "aid": 1, "atext": "Degradation Edman." }, { "aid": 2, "atext": "Chromatography Whatman." }, { "aid": 3, "atext": "Patch-Clamp." }, { "aid": 4, "atext": "Mass spectrometry." }, { "aid": 5, "atext": "Capillary electrophoresis." } ]

[ { "aid": 1, "atext": "That instead of thymine should carry uracil." }, { "aid": 2, "atext": "That would be more sensitive to hydrolysis." }, { "aid": 3, "atext": "That instead of in the nucleus it would be in the cytoplasm." }, { "aid": 4, "atext": "That it could not form double helices." }, { "aid": 5, "atext": "That would give a higher absorbance value at 260 mm." } ]

[ { "aid": 1, "atext": "It is a protein that prevents the double helix from forming in the replication bubble." }, { "aid": 2, "atext": "It is a protein that increases the ability to replicate long fragments of eukaryotic DNA polymerase." }, { "aid": 3, "atext": "It is the protein responsible for the elimination of positive superhelices." }, { "aid": 4, "atext": "It is the typical conformation of the DNA double helix in eukaryotes." }, { "aid": 5, "atext": "It is the enzyme responsible for copying the DNA of the telomeres." } ]

[ { "aid": 1, "atext": "The presence of a repressor and an inducing molecule." }, { "aid": 2, "atext": "The binding of RNA polymerase to DNA." }, { "aid": 3, "atext": "The presence of a repressor and a correpressor molecule." }, { "aid": 4, "atext": "The presence of an activator and its signal molecule." }, { "aid": 5, "atext": "The presence of a mutated repressor that could not bind to DNA." } ]

[ { "aid": 1, "atext": "There is no possibility of elimination of an amino acid in the synthesis of proteins." }, { "aid": 2, "atext": "Through the aminoacyl peptidase activity of the ribosome." }, { "aid": 3, "atext": "A dipeptidase removes the wrong amino acid, before proceeding with the synthesis." }, { "aid": 4, "atext": "Thanks to the fact that amino acids are energy-rich molecules." }, { "aid": 5, "atext": "There is a post-translational sequence review system." } ]

[ { "aid": 1, "atext": "Blocking the incorporation of other components of the transcription machinery." }, { "aid": 2, "atext": "Preventing the remodeling of chromatin." }, { "aid": 3, "atext": "Facilitating the action of helicases." }, { "aid": 4, "atext": "Decreasing the sensitivity of nuclear receptors." }, { "aid": 5, "atext": "Reducing the affinity of histones for DNA." } ]

[ { "aid": 1, "atext": "The two strands are synthesized continuously." }, { "aid": 2, "atext": "Ribozymes intervene." }, { "aid": 3, "atext": "The deoxyribonucleotide triphosphates are oxidized." }, { "aid": 4, "atext": "A primasa intervenes." }, { "aid": 5, "atext": "The two strands remain joined by hydrogen bonds." } ]

[ { "aid": 1, "atext": "Helicasas" }, { "aid": 2, "atext": "Topoisomerases" }, { "aid": 3, "atext": "DNA ligases." }, { "aid": 4, "atext": "Telomerases" }, { "aid": 5, "atext": "DNA polymerase" } ]

[ { "aid": 1, "atext": "It binds to the 30S subunit and inhibits the binding of aminoacyl-tRNA." }, { "aid": 2, "atext": "Inhibits the peptidyltransferase activity of the 50S ribosomal subunit." }, { "aid": 3, "atext": "It binds to the 50S ribosomal subunit and inhibits translocation." }, { "aid": 4, "atext": "It inhibits the initiation and originates an erroneous reading of the mRNA." }, { "aid": 5, "atext": "It causes premature termination by acting as an analog of the aminoacyl-tRNA." } ]

[ { "aid": 1, "atext": "It is a low molecular weight immunoglobulin." }, { "aid": 2, "atext": "It is found in high concentration in platelets." }, { "aid": 3, "atext": "It filters freely through the glomerulus and is secreted by the tubule." }, { "aid": 4, "atext": "It is absent in urine." }, { "aid": 5, "atext": "It is found on the surface of all nucleated cells." } ]

[ { "aid": 1, "atext": "1 / specificity." }, { "aid": 2, "atext": "It depends on the prevalence of the disease." }, { "aid": 3, "atext": "It is the number of patients that give positive results among all possible individuals." }, { "aid": 4, "atext": "It is the quotient between the number of patients who give positive results for this magnitude and the total number of patients considered." }, { "aid": 5, "atext": "It is deducted directly from the minimum detectable value of this magnitude." } ]

[ { "aid": 1, "atext": "In the region 1." }, { "aid": 2, "atext": "In the region ." }, { "aid": 3, "atext": "In the region 2." }, { "aid": 4, "atext": "In the region 1 2." }, { "aid": 5, "atext": "In no position that it is not a protein." } ]

[ { "aid": 1, "atext": "The release of adenylate cyclase (catalyst enzyme of the reaction)." }, { "aid": 2, "atext": "The interference produced by hemoglobin." }, { "aid": 3, "atext": "The high concentration of said enzyme in the cytoplasm of erythrocytes." }, { "aid": 4, "atext": "Hemolysis does not interfere in the determination of LDH." }, { "aid": 5, "atext": "The amount of lactate that is produced." } ]

[ { "aid": 1, "atext": "The LDL receptor." }, { "aid": 2, "atext": "Lipoprotein lipase (LPL)." }, { "aid": 3, "atext": "The Apo CII." }, { "aid": 4, "atext": "The Apo A-II." }, { "aid": 5, "atext": "The Apo B-48." } ]

[ { "aid": 1, "atext": "In cholestatic jaundice we observed: persistent alanine aminotransferase (ALT) increase without elevation of gamma glutamyltransferase (GGT)." }, { "aid": 2, "atext": "In hepatocellular jaundice there is a slight increase in GGT (<5 times the upper limit of reference) and a large increase in ALT (> 10 times the upper limit of reference)." }, { "aid": 3, "atext": "In cholestatic jaundice, a decrease in direct bilirubin and prothrombin time is observed." }, { "aid": 4, "atext": "In hepatocellular jaundice, a decrease in alkaline phosphatase and activated partial thromboplastin time is observed." }, { "aid": 5, "atext": "In both jaundices we can observe a clear decrease in aspartate aminotransferase (AST)." } ]

[ { "aid": 1, "atext": "Anemia due to iron deficiency." }, { "aid": 2, "atext": "Biliary cholestasis." }, { "aid": 3, "atext": "Helicobacter pylori infection." }, { "aid": 4, "atext": "Colon carcinoma" }, { "aid": 5, "atext": "Celiac Disease." } ]

[ { "aid": 1, "atext": "Interferon." }, { "aid": 2, "atext": "Hydroxyurea" }, { "aid": 3, "atext": "Imatinib." }, { "aid": 4, "atext": "Rituximab" }, { "aid": 5, "atext": "Busulfan." } ]

[ { "aid": 1, "atext": "Pernicious anemia." }, { "aid": 2, "atext": "Sickle-cell anaemia." }, { "aid": 3, "atext": "Thalassemia major." }, { "aid": 4, "atext": "Hereditary spherocytosis." }, { "aid": 5, "atext": "Anemia due to iron deficiency." } ]

[ { "aid": 1, "atext": "The largest or most intense peak." }, { "aid": 2, "atext": "The heaviest pair peak." }, { "aid": 3, "atext": "The lightest isotopic peak." }, { "aid": 4, "atext": "The peak that corresponds to its nominal mass." }, { "aid": 5, "atext": "The odd peak heavier." } ]

[ { "aid": 1, "atext": "As a strong anion exchanger in ion exchange resins." }, { "aid": 2, "atext": "As a strong cation exchanger in ion exchange resins." }, { "aid": 3, "atext": "As a weak anion exchanger in ion exchange resins." }, { "aid": 4, "atext": "As a weak cation exchanger in ion exchange resins." }, { "aid": 5, "atext": "It is never used in ion exchange." } ]

[ { "aid": 1, "atext": "Ions with low m / z or lighter values ​​arrive more quickly at the detector." }, { "aid": 2, "atext": "Ions with high m / z or heavier values ​​arrive more quickly at the detector." }, { "aid": 3, "atext": "The ions do not reach the detector." }, { "aid": 4, "atext": "Ions with odd m / z ratio arrive more quickly at the detector." }, { "aid": 5, "atext": "The analysis time that is usually required is seconds." } ]

[ { "aid": 1, "atext": "The membrane responds to other anions besides the hydroxyl ion." }, { "aid": 2, "atext": "The membrane responds to other anions besides the hydrogen ion." }, { "aid": 3, "atext": "The membrane responds to other cations in addition to the hydrogen ion." }, { "aid": 4, "atext": "That the pH is higher than it really is." }, { "aid": 5, "atext": "This error is not described for the glass electrode." } ]

[ { "aid": 1, "atext": "The flow profile is parabolic." }, { "aid": 2, "atext": "The flow profile is practically flat and / or uniform." }, { "aid": 3, "atext": "You can not know its form and direction." }, { "aid": 4, "atext": "The profile of the flow is always inverted." }, { "aid": 5, "atext": "The profile of the flow is never reversed." } ]

[ { "aid": 1, "atext": "3-10 Armstrong." }, { "aid": 2, "atext": "3-10 Nanometers." }, { "aid": 3, "atext": "3-10 Millimeters." }, { "aid": 4, "atext": "3-10 Micrometers." }, { "aid": 5, "atext": "3-10 Centimeters" } ]

[ { "aid": 1, "atext": "They represent the response of an analytical method to unknown concentrations of analyte." }, { "aid": 2, "atext": "They use standard samples that contain the solvent used in the analytical method, but without analyte." }, { "aid": 3, "atext": "They use a standard solution that allows knowing the response of the analytical method to the interfering species that exist in the reagents." }, { "aid": 4, "atext": "They are constructed by preparing samples of known analyte concentration (standards) and determining the response of the analytical procedure to these standards." }, { "aid": 5, "atext": "They are constructed using samples of unknown analyte concentration and measuring the response of the analytical procedure to them." } ]

[ { "aid": 1, "atext": "They cause the data to spread more or less symmetrically with respect to a mean value." }, { "aid": 2, "atext": "They have a definite value and an assignable cause, giving rise to a bias in the results of a series of measures." }, { "aid": 3, "atext": "They come reflected in the precision of a measurement." }, { "aid": 4, "atext": "They are never attributable to instrumental measuring devices." }, { "aid": 5, "atext": "They result in outliers, which differ greatly from the others in a set of duplicate measures data." } ]

[ { "aid": 1, "atext": "Potential difference." }, { "aid": 2, "atext": "Electric conductivity." }, { "aid": 3, "atext": "Thermal conductivity." }, { "aid": 4, "atext": "Electric resistance." }, { "aid": 5, "atext": "Intensity of electric current." } ]

[ { "aid": 1, "atext": "Different molar absorptivities of the absorbent species." }, { "aid": 2, "atext": "Very similar molar absorptivities of the radiations of the polychromatic beam." }, { "aid": 3, "atext": "That the radiant power of the incident beam is modified." }, { "aid": 4, "atext": "That the use of a polychromatic beam always implies significant differences with respect to a monochromatic one." }, { "aid": 5, "atext": "That the relation of incident and transmitted powers is different." } ]

[ { "aid": 1, "atext": "Acid-base balance." }, { "aid": 2, "atext": "Balance of complex formation." }, { "aid": 3, "atext": "Precipitation balance" }, { "aid": 4, "atext": "Oxidation-reduction balance." }, { "aid": 5, "atext": "All those balances that take place in a single phase, usually liquid." } ]

[ { "aid": 1, "atext": "Before the equivalence point, the pH is determined by the excess H + of the solution." }, { "aid": 2, "atext": "After the equivalence point, the excess of hydroxyl ions OH- in the solution determines the pH." }, { "aid": 3, "atext": "At the equivalence point the pH is always 7, since it is determined by the dissociation of the water." }, { "aid": 4, "atext": "At the equivalence point the pH is always acidic." }, { "aid": 5, "atext": "The equilibrium constant of the titration reaction is very low, and it can be said that the reaction \"is not complete\"." } ]

[ { "aid": 1, "atext": "To make possible the EDTA titration of many metals in alkaline solutions an auxiliary complexing agent is used which prevents the metal ion from precipitating as hydroxide." }, { "aid": 2, "atext": "EDTA forms complexes of 1: 2 stoichiometry with some metal ions and therefore has a poor application in quantitative analysis." }, { "aid": 3, "atext": "It is important to choose an adequate pH to carry out the titration because metal-EDTA complexes are more stable at low pH than at high pH." }, { "aid": 4, "atext": "When evaluating a metal ion with EDTA, there is an excess of EDTA at the equivalence point." }, { "aid": 5, "atext": "When evaluating a metal ion with EDTA, there is an excess of metallic ion at the equivalence point." } ]

[ { "aid": 1, "atext": "Cerium." }, { "aid": 2, "atext": "Iodo." }, { "aid": 3, "atext": "Bromine." }, { "aid": 4, "atext": "Permanganate." }, { "aid": 5, "atext": "Dichromate" } ]

[ { "aid": 1, "atext": "It increases as the particle size of the stationary phase increases." }, { "aid": 2, "atext": "It decreases with increasing particle size of the stationary phase." }, { "aid": 3, "atext": "It is greater in the open capillary columns than in the filling columns." }, { "aid": 4, "atext": "Increases with increasing the speed of the mobile phase." }, { "aid": 5, "atext": "It decreases as the speed of the mobile phase increases." } ]

[ { "aid": 1, "atext": "Presents units of concentration-1 time-1." }, { "aid": 2, "atext": "Presents units of time-1." }, { "aid": 3, "atext": "Equivalent to the ratio of the kinetic constants of each stage." }, { "aid": 4, "atext": "Corresponds to the sum of the kinetic constants of each stage." }, { "aid": 5, "atext": "Equivalent to the product of the kinetic constants of each stage." } ]

[ { "aid": 1, "atext": "All components comply with Raoult's law." }, { "aid": 2, "atext": "Only the solute complies with Raoult's law." }, { "aid": 3, "atext": "The solvent complies with Henry's law." }, { "aid": 4, "atext": "All components comply with Henry's law." }, { "aid": 5, "atext": "Only the solute complies with Henry's law." } ]

[ { "aid": 1, "atext": "Presents 3 degrees of freedom, according to the rule of the phases." }, { "aid": 2, "atext": "Presents 1 degree of freedom, according to the rule of the phases." }, { "aid": 3, "atext": "It is characterized because the liquid and gas phases are indistinguishable." }, { "aid": 4, "atext": "It is characterized because there are three phases in equilibrium." }, { "aid": 5, "atext": "It is characterized because there are four phases in equilibrium." } ]

[ { "aid": 1, "atext": "It is a state function." }, { "aid": 2, "atext": "It is an intensive variable." }, { "aid": 3, "atext": "Indicates the spontaneity of any process." }, { "aid": 4, "atext": "It is defined in the First Principle of Thermodynamics." }, { "aid": 5, "atext": "It varies according to the route traveled between the initial and final conditions." } ]

[ { "aid": 1, "atext": "Whose measurement allows to determine molar masses of small molecules." }, { "aid": 2, "atext": "Due to the passage of solute through the cell membrane." }, { "aid": 3, "atext": "That corresponds to the pressure that must be applied to interrupt the passage of solvent through the membrane." }, { "aid": 4, "atext": "That causes a difference of chemical potential of the solvent on both sides of the membrane." }, { "aid": 5, "atext": "Whose effect is minimal and complicated to measure." } ]

[ { "aid": 1, "atext": "The speed of a reaction is directly proportional to the temperature." }, { "aid": 2, "atext": "A high activation energy implies that the speed constant depends markedly on the temperature." }, { "aid": 3, "atext": "The pre-exponential factor or frequency factor (A) is dimensionless." }, { "aid": 4, "atext": "The activation energy depends on the temperature." }, { "aid": 5, "atext": "The activation energy is always negative." } ]

[ { "aid": 1, "atext": "At the initial concentration of reagent." }, { "aid": 2, "atext": "To the number of molecules that are found to react." }, { "aid": 3, "atext": "To the number of collisions of the reactants per unit of time." }, { "aid": 4, "atext": "At the final concentration of the product." }, { "aid": 5, "atext": "To the reaction between the reaction rate and the reagent concentration." } ]

[ { "aid": 1, "atext": "Paracelsus" }, { "aid": 2, "atext": "Claudio Bernard." }, { "aid": 3, "atext": "Richard Alzheimer." }, { "aid": 4, "atext": "Mateo Orfila." }, { "aid": 5, "atext": "Hippocrates" } ]

[ { "aid": 1, "atext": "Digoxin" }, { "aid": 2, "atext": "Barbiturates" }, { "aid": 3, "atext": "Derived amphetamines." }, { "aid": 4, "atext": "Salicylates." }, { "aid": 5, "atext": "Antihistamines" } ]

[ { "aid": 1, "atext": "Diethylene glycol." }, { "aid": 2, "atext": "Methanol" }, { "aid": 3, "atext": "Acetone." }, { "aid": 4, "atext": "Benzene." }, { "aid": 5, "atext": "Carbon tetrachloride." } ]

[ { "aid": 1, "atext": "Opiates" }, { "aid": 2, "atext": "Benzodiazepines." }, { "aid": 3, "atext": "Barbiturates" }, { "aid": 4, "atext": "Tricyclic antidepressants." }, { "aid": 5, "atext": "Digitálicos." } ]

[ { "aid": 1, "atext": "Lung damage" }, { "aid": 2, "atext": "Hematological abnormalities." }, { "aid": 3, "atext": "Neurotoxicity" }, { "aid": 4, "atext": "Ocular toxicity." }, { "aid": 5, "atext": "Ototoxicity" } ]

[ { "aid": 1, "atext": "Abnormal division in mouse uterus cells." }, { "aid": 2, "atext": "Abnormal growth in mouse." }, { "aid": 3, "atext": "Proliferation of a hamster ovary cell culture." }, { "aid": 4, "atext": "Reversal in the growth characteristics of Salmonella." }, { "aid": 5, "atext": "No option is correct." } ]

[ { "aid": 1, "atext": "Superoxide anion" }, { "aid": 2, "atext": "Hydrogen peroxide." }, { "aid": 3, "atext": "Ion superoxide" }, { "aid": 4, "atext": "Radical hydroxyl." }, { "aid": 5, "atext": "It depends on the tissue." } ]

[ { "aid": 1, "atext": "Strychnine." }, { "aid": 2, "atext": "Nicotine." }, { "aid": 3, "atext": "Morphine." }, { "aid": 4, "atext": "Botulinum toxin." }, { "aid": 5, "atext": "Curare." } ]

[ { "aid": 1, "atext": "Camphor." }, { "aid": 2, "atext": "Vanilla." }, { "aid": 3, "atext": "Almond oil." }, { "aid": 4, "atext": "Jasmine oil" }, { "aid": 5, "atext": "Cinnamon." } ]

[ { "aid": 1, "atext": "Nucleophilic substitution reactions." }, { "aid": 2, "atext": "Oxidation reactions to alcohols." }, { "aid": 3, "atext": "Nucleophilic addition reactions." }, { "aid": 4, "atext": "Reduction reactions to carboxylic acids." }, { "aid": 5, "atext": "They are not reactive towards nucleophiles." } ]

[ { "aid": 1, "atext": "Nucleophilic aromatic substitution reaction." }, { "aid": 2, "atext": "Electrophilic aromatic substitution." }, { "aid": 3, "atext": "Addition of halogens." }, { "aid": 4, "atext": "Acid catalyzed hydrolysis." }, { "aid": 5, "atext": "Obtaining alkyl halides." } ]

[ { "aid": 1, "atext": "Through a hydrolysis catalyzed by an acid or a base." }, { "aid": 2, "atext": "Through a reduction reaction with lithium aluminum hydride." }, { "aid": 3, "atext": "Through a reduction reaction with sodium borohydride." }, { "aid": 4, "atext": "Through a reduction reaction with diborane." }, { "aid": 5, "atext": "It is not possible due to the lack of reactivity that characterizes acyl halides." } ]

[ { "aid": 1, "atext": "With a radical nature." }, { "aid": 2, "atext": "With covalent bonds between carbon atoms and metal atoms." }, { "aid": 3, "atext": "With electronic deficit and electrophilic character." }, { "aid": 4, "atext": "Practically not reactive." }, { "aid": 5, "atext": "With essentially reducing character." } ]

[ { "aid": 1, "atext": "It can be considered as an electrophile." }, { "aid": 2, "atext": "It can be considered as a Lewis acid." }, { "aid": 3, "atext": "It can act as a nucleophilic reagent attack center." }, { "aid": 4, "atext": "It can be considered as a nucleophile." }, { "aid": 5, "atext": "It is an example of apolar product." } ]

[ { "aid": 1, "atext": "SiH4." }, { "aid": 2, "atext": "CH4" }, { "aid": 3, "atext": "HCl." }, { "aid": 4, "atext": "PH3." }, { "aid": 5, "atext": "HF" } ]

[ { "aid": 1, "atext": "F." }, { "aid": 2, "atext": "Cl." }, { "aid": 3, "atext": "OR." }, { "aid": 4, "atext": "S." }, { "aid": 5, "atext": "P." } ]

[ { "aid": 1, "atext": "S 2." }, { "aid": 2, "atext": "S 8." }, { "aid": 3, "atext": "S 4." }, { "aid": 4, "atext": "S 6" }, { "aid": 5, "atext": "Sn (n = 10-14)." } ]