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Minor Coordinator: Joshua Nelson (Industrial Design)
Interaction Design deals with the structure and behavior of interactive products and services. Interaction Designers create compelling relationships between people and the interactive systems they use, from computers to mobile devices to appliances; Interaction Designers lay the groundwork for intangible experiences.
The minor, offered by the Department of Design , requires students to complete 21 units of required courses. 12 of these units must be outside the requirements for the student’s major, i.e. the same courses cannot be listed on the minor and the major form. It is the student’s responsibility to make sure
that the prerequisites for each course are met. Students should declare the minor as soon as possible so that they can enroll in courses with waived prerequisites. Students in Majors other than Design Studies, BA , Graphic Design, BFA , or Industrial Design, BS may need to take additional courses to meet prerequisites for the courses required in this minor.
University Graduation Requirements
To be awarded a minor, at least 12 units of coursework must be completely distinct and separate from the coursework in the major, and coursework for the minor must include a minimum of 6 upper-division units (University Policy S16-4). Minor preparation or support courses do not count toward the 12 distinct units. Of the coursework for the minor, at least 6 units must be completed in residence at SJSU. The minimum aggregate GPA for all coursework required for the minor must be at least 2.0. | <urn:uuid:7ea82462-4989-4e35-bd09-6f84d4a28498> | CC-MAIN-2022-33 | https://catalog.sjsu.edu/preview_program.php?catoid=13&poid=7963&returnto=4973 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572908.71/warc/CC-MAIN-20220817122626-20220817152626-00067.warc.gz | en | 0.933365 | 312 | 1.835938 | 2 |
You may not realise it but having penalty points on your license can increase your premium by 60%. On average, drivers who have points on their license pay £370 more than those with a clean license and at a time when we are trying to save money drivers are urged to drive more carefully not just for their safety but for their finances.
Car insurance prices will naturally rise given the current financial climate so if there are ways of reducing the increasing costs, customers should look to take advantage of them. Simply driving carefully and sticking to speed limits can ensure you save a considerable amount of money on your premium.
This is especially important when looking for young driver car insurance. Young drivers typically find it hard to find competitive prices and if they were to have penalty points on their license they could find their policies doubling in price. As young drivers pay around double on a normal policy, this means that a young driver with points could find themselves paying 4 times the average price.
In the last 12 months, over 3 million driving convictions have been recorded which means drivers are not taking notice of the warnings that the car insurance industry has given. Drivers need to work out whether cutting a couple of minutes of a journey is worth the penalty points and large fines.
Traditionally, women pay less for their insurance as they are considered to be safer drivers. However, when it comes to penalty points, research shows that women are more heavily penalised and see increases of up to 80%. This shows that everyone has to be careful when on the roads to avoid large fines.
Driving carefully is a good start to cheaper insurance and customers should follow this up by shopping online and comparing the leading providers with minimal stress and hassle.
Having points on your license can seriously affect your insurance premium. Especially when new drivers look for cheap car insurance as they are affected the most. For the best prices on car insurance shop online and compare the leading insurers.
We have many more Auto Insurance Help Articles Now Available. | <urn:uuid:bf5b4e1e-2c57-4ec3-9eb2-e7fa42a06c54> | CC-MAIN-2017-04 | http://www.007aj.com/car-insurance-paying-the-penalty-for-reckless-driving/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280900.71/warc/CC-MAIN-20170116095120-00008-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.969697 | 398 | 1.820313 | 2 |
News: U.S.F.S.R. Monday, Jun. 14, 1943 U.S.F.S.R. In London 60 years ago, when he was red-bearded and in his 20s, George Bernard Shaw joined the newly founded Fabian Society.† It was a socialist group, ambitious to reconstruct "society in accordance with the highest moral possibilities. " The Fabians rejected the Marxian doctrine that socialism must be preceded by revolution. They believed in "gradualism," holding that the socialist principle was partially embodied in most governments and capable of extension through existing political parties. Last week, a bit nostalgically, with the old flashing wit, venerable G.B.S. relived those early days—and almost forgot that he was reviewing G. D. H. Cole's Fabian Socialism for the London Tribune: "This Fabian Society seemed just what I wanted. . . . We began by imposing on the Liberal Party ... a socialist program. . . . We . . . founded the London School of Economics, which has produced Beveridge; added The New Statesman to the weekly press; established an independent labour party. . . . "In the course of nature, we young upstarts became an Old Gang. ... Of the seven Fabian essayists of the '80s the only survivors are [Sidney] Webb and myself, both octogenarians. ... Be patient with us: we shall not be long now. . . ." Read more: Foreign News: U.S.F.S.R. - TIME The Fabian Society had really been founded 62 years ago, but, because of the war, it delayed the celebration. The postponement was in character; Fabius Cunctator (The Delayer) had worn out Hannibal in the Second Punic War* by what Livy called "masterly inactivity." The earnest young men & women of the 1880s who believed that socialism (not the Marxist brand) would come with what Webb called the "inevitability of gradualness" took Fabius as their exemplar. They considered violent revolution unnecessary, believed their Utopia could be achieved by "permeating" existing institutions. Read more: Foreign News: Easy Does It - TIME Will a national debt of $300,000,000,000 bankrupt the U.S.? Where will the money to finance postwar full employment come from? How can jobs be found for 12,000,000 returning soldiers & sailors? Last week, The Twentieth Century Fund ***published Stuart Chase's brightly written answers under the title Where's the Money Coming From? ($1). Read more: FISCAL: Compensatory and Mr. Chase - TIME Fabian Society - Wikipedia, the free encyclopedia ***The Century Foundation So who are todays Fabian society ? | <urn:uuid:84b9ba93-40e1-4fd4-aaba-6b00a0071180> | CC-MAIN-2017-04 | http://www.usmessageboard.com/threads/the-fabian-society.136380/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281331.15/warc/CC-MAIN-20170116095121-00221-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.947089 | 577 | 1.960938 | 2 |
字幕表 動画を再生する 英語字幕をプリント Welcome back from the weekend. We`re happy you`re taking 10 minutes for CNN STUDENT NEWS. I`m Carl Azuz at the CNN Center. Our first story takes us to a nation of 26 million people between Saudi Arabia and the Gulf of Aden. It`s Yemen. Its government was overthrown in January by Houthi rebels who had been at odds with the Yemeni government for years. The country is very unstable. A terrorist attack on two mosques last Friday killed more than 130 people and wounded hundreds more. The ISIS militant group said it was responsible. But al Qaeda also operates in Yemen and the U.S. says security there continues to get worse. That`s why the American military pulled all of its remaining personnel out of the country this weekend. In Yemen`s capital, the American Embassy was closed last month. In our coverage of the conflict in Ukraine, we`ve talked about how relations between the U.S. and Russia have declined. According to Gallup surveys, about half of the American population had a positive view of Russia three years ago. Today, 70 percent of Americans have an unfavorable view and 82 percent of Russians disapprove of U.S. leadership. When Gallup asked Americans earlier this year what country they`d consider to be America`s greatest enemy, 18 percent answered Russia, the most of any nation worldwide. North Korea was right behind that. So it`s significant that with relations between the U.S. and Russia being at their lowest point since the end of the cold war, Russia would invite North Korea`s leader to an event in Moscow. Facing a backlash from the West, Russia is looking East. President Vladimir Putin inviting North Korean leader Kim Jong-un to Moscow to attend upcoming World War II anniversary celebrations. A Russian officials says North Korea`s supreme leader is expected to attend, but so far no formal confirmation from Pyongyang. You`ve seen the number of meetings that he`s had with Western leaders in Europe decline. And so the Russians have talked about this Asian alternative. And this is including some outreach to China, but other countries in Asia, to try to portray Mr. Putin as not isolated, which in fact is the case. The Kremlin says 68 world leaders were invited to the Victory Day celebrations on May the 9th, but some leaders, including President Obama, have declined. Relations with the West are strained following Russia`s annexation of Crimea from Ukraine. But recently, Moscow and Pyongyang have been fostering warmer relations. The two countries even declared 2015 their year of friendship. If Kim attends, it would be his first official trip outside North Korea since inheriting the leadership in late 2011. If he`s able to go to meet Putin in Moscow or elsewhere in Russia, this would appear to be a sign that he has completely consolidated control and he`s confident enough to leave the nest and go do statesmanlike things around the world. And Putin continues to flex Russia`s military muscles. Defense officials saying nearly 80,000 troops have been placed on full combat alert. On Wednesday, NATO jets intercepted a number of Russian military aircraft as they neared Latvian airspace, further rattling nerves among Russia`s neighbors. India has the second highest human population in the world. But it`s number one when it comes to tigers. It`s home to about half the world`s tigers. They typically live about eight to 10 years in the wild, though all tiger subspecies are endangered. India doesn`t have nearly as many as it used to, but their numbers are growing again, thanks, in large part, to conservation efforts. Here`s what one of those efforts looks like. When people report tiger attacks, they say it came out of nowhere. It is staggering to think that there were tens of thousands of tigers in the forests of India. Now, there`s just over 2,200, something like that. Oh, that`s very good. Oh, you`re good. How are things going? How goes the fight? It`s been good. The numbers say there are 2226 tigers in India in the wild. Who else has seen a tiger? Lots of you. Conflict has not really gone higher than the last few months. Your real passion is saving tigers, through conflict resolution, there`s a very visceral fear of the tiger throughout much of India. So if one comes into a village, they`re often killed. And you go into these places and try to talk people down, try to make them appreciate the value of a forest with wild tigers. It`s all about people and their code of conduct, because you can`t get people out of the forest, you can`t get animals out of these human dominated forests. This is the corridor that we`ve created. You took me to this little farm you purchased between two tiger preserves and it has turned into wildlife superhighway. When I show pictures that this is from my kitchen, I`ve shown that I have tigers walking here, anyhow, it freaks them out. You`re trying to convince your neighboring farmers that maybe you should stop farming and let your land go wild. If you stop farming and if you let free forests come back and get some economic benefits from eco-tourism, it would be a win-win situation. As part of our presentation, we now present three schools that are present on today`s Roll Call. The Rams are here from San Antonio, Texas. It`s the home of John Marshall High School. The Wildcats are watching. LaGrange is in Ohio. It`s where we found Keystone High School. And it`s knight time. Castle Heights Middle School is online from South Carolina in the city of Rock Hill. An international film festival kicked off last October. It had some unique characteristics. One, it was open only to students between kindergarten and twelfth grade. Two, its theme was the impact of giving back, the focus on serving others. Three, out of more than 1,500 submissions, 15 of the short films were screened last Friday at the White House. President Obama, Oscar winning actress Hillary Swank and Oscar winning director Steve McQueen were there. It was the second year for the event, which was sponsored by the American Film Institute and participant media. Finalists were invited to attend the screening and they got to go to workshops afterward focused on sharpening their skills in filmmaking. He`s an example of what one of the White House`s 15 selections looked like. What will you give back? People get stuck when asked. I don`t know, their faces respond. Oh, if they only saw what I saw. We are capable of giving so much, for we have been given all we need to give it all up. We have a beating heart, air in our lungs. Don`t you see what I see? The teacher passionately giving away her education for the sake of the student who is full of determination, determination to rise, to dream, to fight, to create. Giving their imagination for others to find inspiration. Giving their stories in hopes for others to see what they see. Giving their voice for others to find their own, giving their words for others to know we are not alone. The will to give has no age. Here`s a wise coach -- giving away his child-like heart for boys who just want to have fun, a humble custodian giving away her sore hands for others to live in cleanliness. The impact transcends time and space. So here`s to giving it all away. Before we go, a fish called Greedo. "Star Wars" might get the name. For the rest of us, it`s one crude catfish. It was discovered in 1998 but it wasn`t until this year that it was designated a new species. Because of its large eyes and bristling bristles, a researcher thought it looked like a short-lived "Star Wars" character. If you were looking for the off screen version of Greedo, you can find it in the waters of Northern Brazil. It might lack the aura of an angelfish, the colors of a clown fish or the regality of the regal tang, but it`s not Greedo for attention. There are many fish in the sea and this cat is catching coverage swimmingly from fins around the galaxy. This is CNN STUDENT NEWS and that`s our catch of the day. | <urn:uuid:d4b96d18-fd51-400e-963a-d4831c174535> | CC-MAIN-2022-33 | https://jp.voicetube.com/videos/22697 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573118.26/warc/CC-MAIN-20220817213446-20220818003446-00667.warc.gz | en | 0.974261 | 1,753 | 2.5 | 2 |
Originally Posted by martijnburger
I'm really imbarresed to have to ask this question because there are already al lot of threads to be found regarding the same question, however, I haven't been able to get the solutions proposed there working on my system.
My configuration is:
Sun JDK 1.6
When I try to compile a simple .java I get a compiler error stating:
package javax.servlet does not exist
I've tried including /usr/share/java/tomcat6-servlet-2.5-api.jar which didn't solve the problem.
What am I doing wrong?
The problem is that servlet.jar is not on your CLASSPATH. You will need to export it in order to get it to compile. Something like this should do:
NOTE: the above may not work, I am guessing the path only
Personally, I would not touch servlets without an IDE. With an IDE, you could simply add your jars to your project, painless, letting you, the programmer, to do what you are supposed to do: program
Just a hint | <urn:uuid:1b1c7bea-9880-4a77-9af4-1bb9fa98b9cd> | CC-MAIN-2017-04 | http://www.linuxquestions.org/questions/linux-server-73/package-javax-servlet-does-not-exist-on-fedora-10-tomcat-6-a-695966/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560282202.61/warc/CC-MAIN-20170116095122-00552-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.912989 | 238 | 1.796875 | 2 |
READ OUR 2021 BOOK
WHO'S IN OUR 2021 BOOK
Healthy NewsWorks student journalists interviewed nearly 20 health and community leaders about the pandemic’s challenges for Leading Healthy Change In Our Communities 2021: Doing the Undoable in a Pandemic.
Answering the call
- Lorraine Brown, B.S.N., R.N., emergency department nurse, Einstein Healthcare Network
- Pierre Chanoine, M.D., pediatrician; volunteer with Black Doctors COVID Consortium
- Bhavna Sharma, M.D., critical-care specialist, Einstein Healthcare Network
Serving behind the scenes
- Diane Amati, quality control/quality assurance lead technologist for infectious disease, Quest Diagnostics Horsham Laboratory
- Erika Keith, customer service representative, Brown Family ShopRite in East Norriton
- Sherri McClintock, hematology supervisor, Quest Diagnostics Horsham Laboratory
- Jane Reedy, clinical operations manager, Quest Diagnostics Horsham Laboratory
- Michael Solomonov, chef, Zahav Restaurant
- Patrick Walsh, director of programs, Martha’s Choice Marketplace
Spreading the message
- Perla Lara, editor in chief, Impacto
- Paul Offit, M.D., director of Vaccine Education Center, Children’s Hospital of Philadelphia
Helping others cope
- Kevin R. Carter, M.S.W., clinical director, Uplift Center for Grieving Children
- Howard Stevenson, Ph.D., Constance Clayton Professor of Urban Education, University of Pennsylvania
- Rev. Dr. Alyn E. Waller, senior pastor, Enon Tabernacle Baptist Church
Feeding the soul
- Cydney Brown, Philadelphia Youth Poet Laureate
- Lesa Cline-Ransome, award-winning children’s book author
- Kerri Ryan, assistant principal violist, Philadelphia Orchestra
Staying in shape
- Duriel Hardy, M.D., pediatric neurologist, Children’s Hospital of Philadelphia; marathoner
- Dong Lien, assistant strength and conditioning coach, Philadelphia Phillies
We thank them for their contributions to our communities and for sharing their stories with our student journalists.
A PREVIEW OF OUR EVENT
Fifth grader Jayvyn asks NFL player Malcolm Jenkins: “What has the pandemic taught you?”
Eighth grader Joshua asked Merck CEO Kenneth Frazier about the role business can take in addressing political issues.
Program alumna Kayla talked to us about the incredible experiences she had with Healthy NewsWorks, and how the program set her up for success this year:
SPECIAL GUESTS INCLUDE
Kenneth Frazier, J.D., is chairman and CEO of Merck. A strong advocate for social justice and economic inclusion, he has been the recipient of such awards as the Anti-Defamation League Courage Against Hate Award, the NAACP Legal Defense and Educational Fund National Equal Justice Award, and the National Minority Quality Forum’s Lifetime Achievement Award. He has made numerous contributions to the legal, business, and humanitarian fields.
Malcolm Jenkins is an NFL safety who has played for both the New Orleans Saints and the Philadelphia Eagles. He’s won two Super Bowls — one with each team. He is the founder of the Malcolm Jenkins Foundation, which aims to effectuate positive change in the lives of youth, particularly those in underserved communities. It operates in Pennsylvania, New Jersey, Ohio, and Louisiana.
Michael Osterholm, Ph.D., M.P.H, is director of the Center for Infectious Disease Research and Policy at the University of Minnesota. An epidemiologist, he was a member of President-elect Joe Biden’s Transition COVID-19 Advisory Board. He is the author of the 2017 best seller, Deadliest Enemy: Our War Against Killer Germs.
WATCH A REPLAY OF OUR EVENT!
Community Healthcare Champion
Amy Ginensky and Andrew Rogoff
Lisa Kabnick and John McFadden
Laurie Hack and Jack Hershey
Jim & Kay Gately Charitable Fund of Vanguard Charitable
The Green Street Fund
Nina M. Gussack
Moriah and David Hall
Elizabeth B. Rappaport, M.D., and Daniel Fife, M.D.
BTC Envelopes & Printing LLC,President Andrew D. Magnus
Luther T. Clark, M.D.
Crowley Family Foundation of Fidelity Charitable
The Gamble Family Foundation
Elizabeth H. Gemmill
Katherine Hatton and Richard Bilotti Fund of Princeton Area Community Foundation
Omar D. Joseph
King of Prussia Rotary Club
Betsey and Mike Useem
Drs. James Buehler and Lydia Ogden
Children’s Hospital of Philadelphia—Community Partner
Chuck and Courtney Ercole
Andrea Knox and Jonathan Hodgson
Langan Engineering & Environmental Services
Jane Isaacs Lowe
National Association of Asian American Professionals Philadelphia Chapter
Robert and Karen Sharrar
Elizabeth and Tony Vale
The Willing & O’Donnell Charitable Giving Fund of the T. Rowe Price Program for Charitable Giving
Anne Jeffrey Wright | <urn:uuid:2d31ed87-d588-4c21-9c95-868b88a0f68f> | CC-MAIN-2022-33 | https://www.healthynewsworks.org/2021-celebration/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573193.35/warc/CC-MAIN-20220818094131-20220818124131-00469.warc.gz | en | 0.855025 | 1,164 | 1.515625 | 2 |
From 1 January 2020, a new condition has been added to your refrigeration and air conditioning (RAC) permit.
Permit holders must not charge RAC equipment with a refrigerant that has a higher global warming potential (GWP) than the refrigerant the equipment was designed to use.
Such charging is an offence under the Ozone Protection and Synthetic Greenhouse Gas Management Regulations1995 and penalties apply. This offence applies to any person carrying out work on RAC equipment, regardless of whether they have a permit.
RAC equipment is inherently leaky. If you replace a no GWP or low GWP refrigerant with a high GWP refrigerant, you will ultimately get more global warming emissions.
The ban on charging RAC equipment with refrigerants that have a higher GWP than the equipment was designed to use supports Australia’s response to the hydrofluorocarbon (HFC) phase-down and the transition to no GWP or low GWP refrigerants. | <urn:uuid:cacb4b73-9116-4d43-ba17-b7a2bc2c3da7> | CC-MAIN-2022-33 | https://www.arctick.org/information/prohibited-charging/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570741.21/warc/CC-MAIN-20220808001418-20220808031418-00067.warc.gz | en | 0.94718 | 203 | 2.171875 | 2 |
Learn about Edema
Edema is a condition that leads to constant bloating and retention of fluids within the body’s tissue, but it isn’t a disease in and of itself, but rather a symptom that comes with other health problems such as circulation problems, as well as digestive or kidney issues. Edema is the constant retention of fluids in the peritoneum (a membrane that covers the organs located in the abdominal and chest area). This symptom is really common in the upper part of the body, but with certain diseases it can sometimes occur in the ankles, wrists, or even the neck. Learn more about edema below!
Edema, an important warning sign
If you don’t treat certain symptoms, it can affect the proper functioning of vital organs like the heart, liver, and lungs since the swelling puts pressure on these organs and reduces the space they have to function as they should. Swelling in the lower part of the body is known as edema, but this doesn’t change the color of the skin nor does it cause any pain. When a patient shows signs of edema, the root of the problem needs to be found. One possible reason can be congestive heart failure since it alters the heart’s rhythm which can lead to retention of fluids. This symptom can commonly be seen in the limbs.
Edema can also be a pulmonary issue, with a cough being the primary symptom. When a patient has constant swelling in a certain part of the body, a doctor needs to be consulted as soon as possible. The patient will likely be treated with diuretics to rid the body of extra fluids through urination. It is also really common for edema to be a symptom of renal problems. When a person suffers from kidney failure, he or she loses the capacity to filter out the water in the blood and as a result the person produces less urine. Edema as a result of kidney failure can lead to a progressive swelling in the limbs, which is one of the most notable symptoms.
NOTE: We recommend the following articles if you would like to treat swelling and fluid retention:
- Teas that reduce fluid retention
- Natural Ways to Prevent Fluid Retention
- How to Eliminate Excess Fluids in Under a Month
This condition can affect anyone and its treatment will depend on what type of edema you suffer from. It can be a serious health problem for anyone who suffers from it. It is also related to fatal conditions such as heart and kidney failure, which are two of the main causes of edema. This symptom requires immediate attention since if it is left unattended it can result in death. | <urn:uuid:10450227-40ea-430d-a592-577c69697d62> | CC-MAIN-2017-04 | https://steptohealth.com/learn-about-edema/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280929.91/warc/CC-MAIN-20170116095120-00425-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.958471 | 544 | 3.609375 | 4 |
Every Wednesday on our blog, we highlight an article, book or a blog in our “What We’re Reading” series. We’ll feature pieces or works that are noteworthy, inspiring, educational or relevant to the work we do at Opportunity. We welcome your comments in the comment field below–tell us what you’re reading, or respond to the piece that we’ve highlighted.
This week we’re reading the September 2010 report fromMediaPlanet in USA Today entitled “Investing in Women & Girls: Dedicating Resources to a Single Woman Has a Ripple Effect on her Entire Community.” It’s an independent report featuring expert editorials–from everyone from Oprah Winfrey tohttp://www.opportunity.org/blog/melinda-french-gates-on-the-impact-of-agriculture-finance/Melinda Gates[/intlink] to Corinne Woods, the director of thehttp://www.opportunity.org/blog/un-gathers-this-week-to-eradicate-poverty-through-the-mdgs/U.N. Millennium Campaign[/intlink]–with testimonials as to why it is essential to be investing in http://www.opportunity.org/womens-opportunity-network/women and girls[/intlink] on a global scale.
In addition to the editorials and interviews, the report outlines five key steps to change the world by empowering women and girls:
- Provide Quality Healthcare
- Access to Financial Resources
- Raise Awareness
- Encourage Gender Equality
- Educate Girls
Corinne Woods, director of the U.N. Millennium Campaign:
- “The Millenium Development Goals have the power to bring about tangible change in the lives of women and girls.”
- “Make sure your elected representatives know that you support the administration’s new MDG strategy and efforts to prioritize the Millennium Development Goals. Advocate for the Goals in the media and educate your friends and neighbors.”
- Go to endpoverty2015.org and standagainstpoverty.org to learn how you can do more
“The New Businesswoman”:
- Afghan entrepreneur Masooma Habibi participated inhttp://www.opportunity.org/blog/opportunity-attends-the-10000-women-leadership-academy/Goldman Sachs’ 10,000 Women Program[/intlink], where she learned practical skills like accounting, human resources management, and marketing.
- After graduating in 2009, she started her own electrical engineering firm, and has managed to grow her business despite competition from male-owned companies, cultural prejudice in a predominantly male field, and security risks.
- Masooma’s goal is to start an electrical laboratory, and she hopes to establish a nonprofit organization to create job opportunities for all Afghan women.
- “A businesswoman makes her own money to support herself and change her life—but it wasn’t just to have my own business. I knew that if I had a successful business, I could help the poor people around me.” – Goldman Sachs 10,000 Women Graduate Masooma Habibi
Q & A: Melinda French Gates on the Gates Foundation’s commitment to women’s philanthropy:
- “We’re seeing tremendous momentum around the idea that investments in women save lives and help their families, communities and nations to thrive.”
- “Technology has already had a huge impact on women’s lives [in the developing world].”
- “In Kenya, more than nine million people are using cell phones to transfer money [and manage their finances]. This means that women who previously may not have had access to a banking system can now send money to their children’s schools or other family members, or set up and access a savings account. This is revolutionary.”
Oprah Winfrey, Founder of the Oprah Winfrey Leadership Academy for Girls, South Africa:
- “When you educate a girl… you start to affect her family, her community, her nation. When you educate a girl, that girl becomes a woman who understands the value of an education and educates her children.”
- “[At the academy,] we support the development of a new generation of women leaders who, by virtue of their education and service, will lead the charge to transform themselves, their communities, and the larger world around them. [...We will] help raise the next generation of transformative South African leaders.”
Interested in learning more about how Opportunity invests almost 85% of its donor dollars to providing http://www.opportunity.org/what-is-microfinance/microfinance[/intlink] services to women? Attend our http://www.opportunity.org/opportunity-international-conference/breakout-sessions/breakout session[/intlink]–Investing in Half the Sky: Why Women? Why Now?–at the fall microfinance conference, Oct. 8-9, in Washington, D.C. Hear stories of hope and empowerment from Alice Gasatura, director of credit support at Opportunity Rwanda; Julie Hindmarsh, member of our Board of Directors; and Ruth-Anne Renaud, our VP of women’s philanthropy. http://www.opportunity.org/opportunity-international-conference/Click here[/intlink] to see the full agenda for the conference, and to register[/intlink]. | <urn:uuid:e7b6d988-918f-48dd-b75f-dd8a3804ea85> | CC-MAIN-2017-04 | http://opportunity.org/news/blog/2010/09/what-were-reading-investing-in-women-girls | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280483.83/warc/CC-MAIN-20170116095120-00300-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.904567 | 1,183 | 1.734375 | 2 |
Are you in need of a CNC machine shop? If so, you’ve come to the right place. However, if you’re unsure whether a machine shop is ISO-certified, read on. This certification will help you improve efficiency and quality. It also demonstrates your commitment to proper documentation and traceability. Learn how you can obtain the certificate from your local machine shop. You can also find out more through local machine shops, like the certified machine shop Houston TX.
Processes, procedures, and organization of a machine shop
The Processes, Procedures, and Organization of a Certified Machine Shop (QMS) is a critical component of ISO 9001:2015 certification. To meet these standards, a machine shop must be lean and efficient. Therefore, it should document its processes in detail so everyone involved can see where they need to improve. In addition, standardization of operations is key to addressing future challenges. Without standardized methods, improvement is impossible.
Certification from ISO 9000 improves a machine shop’s quality management system by promoting a customer focus and company-wide commitment to continuous improvement. In addition, ISO certification promotes standards in processes, measures waste, and accountability. It also increases the value of a machine shop’s work and helps it compete with other shops. The benefits of ISO certification go beyond increasing profitability, however. Listed below are some of the benefits of ISO certification.
Documentation in machine shop processes
Adequate documentation in the machine shop includes the following aspects:
Training: To be a productive machine shop, a trained workforce is a must. Without proper tools, no one can do the job efficiently. Suitable conditions and maintenance of tools extend tool life. Documentation will decrease knowledge loss and increase productivity, especially for training purposes. Identify the highest priorities and begin by addressing them. Machine shops are notoriously creative, so addressing them requires action.
Detailed process drawings: A process drawing can contain much-clarifying information. Process engineers can identify machined surfaces and cutting tools. Detailed documentation of quality control information can relate specific sizing adjustments to CNC methods. Moreover, exploded diagrams are easy to make and excellent for training. In a CNC shop, process drawings are tied to the shop’s ERP system. Annotated notes are handy for small manufacturers.
Customer concentration issue
While it may seem like a minor concern, a high level of customer concentration in a machine shop company can be detrimental to the business’s success. You can avoid this problem by analyzing the customer concentration within the machine shop business. The term customer concentration refers to the amount of revenue a company gets from its customers. For instance, the business will lose that much money if four customers account for 25% of its annual revenue. Numerous risks are associated with high customer concentration in a machine shop business.
A high-quality machine shop will be able to attract and retain customers. Customers are more likely to return to a machine shop that meets quality standards. While this may seem minor, it is a significant problem. To solve this problem, shop owners should implement a process that ensures quality work from all customers. One of the best ways to improve customer concentration in a machine shop is to implement procedures that streamline operations.
Training for ISO 9001 certification
If your machine shop wants to prove that it complies with internationally recognized standards, you should consider investing in ISO 9001 certification. While you may not have to be an individual to pursue this certification, many vital customers, government departments, and industry groups require it. Therefore, regardless of size, training for ISO 9001 certificate for machine shops is crucial for your business’s success.
ISO 9001 certification is an excellent way for companies to demonstrate that they take their jobs seriously and value their employees. These standards outline the best practices in delivery, efficiency, and workplace safety. The benefits of ISO 9001 certification are numerous. Whether you are a small machine shop or a large, thriving business, achieving this certification will boost your business’s revenue, and your customers will thank you.
Cost of ISO 9001 certification
There are several reasons why machine shops should pursue ISO 9001 certification:
- The process improves quality and efficiency.
- It assures the customer that the company works according to the highest standards.
- The certification is a valuable marketing tool, and some industries require vendors to have ISO certification.
However, it can be expensive. Nevertheless, the benefits outweigh the costs. Ultimately, it helps increase the revenue of a machine shop and reduce customer loss.
However, there are also some downsides to undergoing ISO 9001 certification. While the initial certification process itself is free, ongoing training is expensive. Additionally, the requirements are continually assessed to ensure that the certificate is still valuable and relevant. This way, the overall cost of ISO 9001 certification for machine shops will be lower in the long run. And, since it’s ongoing, it will continue improving the shop’s quality. | <urn:uuid:04adadcf-ce6c-411b-bfea-10be2be9c7be> | CC-MAIN-2022-33 | https://www.myworldgame.co.uk/what-is-considered-to-be-a-certified-machine-shop/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571472.69/warc/CC-MAIN-20220811133823-20220811163823-00674.warc.gz | en | 0.937929 | 1,020 | 2.046875 | 2 |
The world has changed so much just in the last decade. Today, social media is a ubiquitous form of communication and your online identity is an extremely important part of your overall brand as a potential employee. So, what happens when you apply for a new job? Are potential employers Googling your name to learn more about you before they bring you in for an interview? The answer is yes!
Before you declare your privacy is being invaded, consider these four reasons employers are Googling you to learn more.
Are You Really an Expert?
If you tell a potential employer that you’re an expert on a subject, you might want to make sure you have information to back you up. In fact, if you really want to position yourself as a thought leader, a blog can get that message across. A recruiter may google you to see if your experience really does line up with what you say you can do, so make sure it does!
How Have You Talked About Former Employers?
Employers are sensitive to negative behavior. A disgruntled employee can affect the entire staff, even of previously satisfied workers. If they google you and find red flags where you’ve posted negative information about former employers, co-workers or managers, you may not be considered for the position.
Do You Fit with Their Corporate Culture?
Of course, they aren’t just looking for negative information to find out why not to hire you. They are also looking for reasons to say yes. Specifically, they want to know if you’re really a fit with their corporate culture. Are you more casual and laid back? Are you more conservative and prefer to follow rules. Some insight into your personality can be discovered on your public social media profiles.
Is Your Social Presence Inappropriate?
Lastly, they also want to make sure that you are an appropriate representative of their company. Illegal or immoral activities that are made public via social media can impact your career or the possibility of getting hired in a negative way. Review your social media profiles, make sure your public profile pictures aren’t inappropriate, and make sure you have your security settings high enough to prevent unnecessary access to personal information.
Do you want to know how and why employers are searching your online presence? Contact the team at Harvard Resource Solutions today. | <urn:uuid:a629e174-6887-4e86-94fe-3836ec96d681> | CC-MAIN-2022-33 | https://www.hrsus.com/2017/04/21/googled-prospective-employers/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572833.78/warc/CC-MAIN-20220817001643-20220817031643-00270.warc.gz | en | 0.958552 | 472 | 1.585938 | 2 |
In the past, we have released a policy brief on the indicators that we can use to monitor the sustainable development of the European bioeconomy. With this info-pack, we will elaborate more on the tools we need to quantify those indicators. It will serve as a guide for policy makers and the industries alike to make better decisions on the bioeconomy in the long-run.
Models have been used to assess the potential impacts of different strategies put up in relation to the bioeconomy in Europe. The problem however is that present-day models only give you partitions of the bigger picture. Together they run the risk of overlaps and knowledge gaps, and therefore give us an incomplete and unfitting overview of the current situation of the bioeconomy within Europe.
We have worked on identifying five suitable simulation models, namely, AGMEMOD, BIOMAT, EFISCEN, EFI-GTM, and MAGNET. Together, they will cover multiple aspects of the bioeconomy. These have been further improved to accommodate emerging bio-based activities and products in the European market. The BioMonitor Model Toolbox thus allows policy makers and key actors within the bio-based industry to analyse the decisions they have made previously, and to decide the possible actions they must take to be aligned with the United Nation’s Sustainable Development Goals.
This info-pack elucidates on the different elements that make up the BioMonitor Model Toolbox and how these work with each other. It also outlines the similarities and differences of the chosen models based on their function as well as the value chains, indicators, geographical location and timeframe they cover.
Lastly, this document will serve as a prelude to our upcoming policy briefs that will elaborate more on the future scenarios we have developed for decision makers to gain new policy insights about the European bioeconomy by 2030 and 2050. | <urn:uuid:177c8c49-6a0a-44c2-916a-fcc253662625> | CC-MAIN-2022-33 | https://biomonitor.eu/news/what-tools-do-we-need-to-make-more-sustainable-choices-for-the-bioeconomy/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572021.17/warc/CC-MAIN-20220814083156-20220814113156-00075.warc.gz | en | 0.94471 | 379 | 2.015625 | 2 |
Postgraduate researchers from the University of Birmingham have hailed a major Staffordshire heritage project as a shining example of the reuse of a historical site, during a visit to Newcastle-under-Lyme’s oldest building.
The researchers, from the University of Birmingham’s Ironbridge International Institute for Cultural Heritage (IIICH), visited the 17th century building, currently being sympathetically regenerated as part of a wider £13.5m development by state-of-the-art care village operator Belong, to see first-hand the process of bringing new life to a site of historical interest. The visit also provided postgraduate students and doctoral researchers with a chance to observe the delivery phase of a Heritage Lottery Fund backed project.
A £1.8m grant from the Heritage Lottery Fund is allowing Belong to completely renovate the Grade II listed building to create The Belong Heritage Gallery. When it opens in April this year, the new facility will serve as a centre for world-leading dementia care and document the property’s history.
In the 18th century, the three-storey building on Lower Street was home to Newcastle’s only pottery, before becoming a coaching inn. It was later known as the ‘Old Pomona Inn’ and became the iconic Maxims nightclub in the 70s.
A campaign to engage the local community has been run alongside the creation of the Belong Heritage Gallery. The Maxims Live! campaign has involved a series of workshops to gather people’s memories of Maxims nightclub and the building’s more distant past. The memories are currently being turned into a play by the New Vic Theatre, which will be performed when the building reopens, and have inspired a number of features in the heritage gallery.
Jamie Davies, teaching fellow in cultural heritage at the University of Birmingham’s IIICH, said: “We are very grateful to Belong for facilitating the tour of the Belong Heritage Gallery prior to its public opening. The unique aspects of the project, including its funding streams and planned use as a centre for heritage engagement, make it a particularly interesting case study. Belong are effectively managing the challenges of heritage conservation while ensuring the building has a future role to play in the local community.”
Tracy Paine, Deputy Chief Executive of Belong, said: “We were delighted by the request from the University of Birmingham to visit the heritage gallery site. The old Maxims building has played a huge role in Newcastle’s history, so it’s a privilege to be able to preserve it for future generations. We are now looking ahead to putting the finishing touches to the gallery before it opens to the public.” | <urn:uuid:85bc4ee2-b4d3-47f3-84ea-cbd8341f930d> | CC-MAIN-2022-33 | https://thecareruk.com/heritage-researchers-praise-maxims-makeover/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573533.87/warc/CC-MAIN-20220818215509-20220819005509-00274.warc.gz | en | 0.957415 | 561 | 1.921875 | 2 |
UK Visitor Visas allow people to enter the UK for short periods for leisure, to engage in limited business activities, or simly to travel through the Uk en route to elsewhere. This section has 3 pages:
- Standard Visitor Visa: This visa allows people to enter the UK for travel, tourism, and leisure purposes; as well as short term unpaid business appointments, academic conferences, participating in sporting events or creative/artistic work, and receiving private medical treatment in the UK.
- Permitted Paid Engagement Visa: this visa allows people to enter the UK for up to a month to take part in a paid engagement. Such as a public speaking engagement, chairing a meeting, or attending a conference.
- Who needs a UK visitor visa?: This guide gives details on who needs a visitor visa to enter or travel through the UK.
Further information, help, and advice
Workpermit.com has been in the immigration services business for thirty years, and have helped thousands of people to study and work in the UK. Workpermit.com and its associated companies are acting under Section 84 of the Immigration and Asylum Act 1999. | <urn:uuid:45d0402d-25a0-4a86-b2fe-0782298aa96e> | CC-MAIN-2022-33 | https://workpermit.com/immigration/united-kingdom/uk-visitor-visas | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571150.88/warc/CC-MAIN-20220810070501-20220810100501-00677.warc.gz | en | 0.943419 | 234 | 1.765625 | 2 |
by David D. Levine
$0.99 (Short Story) ISBN 978-1-61138-219-8
Walker’s got a problem. A human salesman on an alien world, he’s got software to sell. But he doesn’t understand the language or the culture, and he’s running out of resources. Sometimes survival means understanding the difference between what’s most valuable and what’s most important. Translated into 7 languages, Tk’Tk’Tk won the Hugo Award for Best Short Story in 2006.
Praise for Tk’Tk’Tk:
“Asimov’s for March contains a gloriously old-fashioned story of incomprehensible obsequious aliens giving a human trader the run-around: ‘Tk’Tk’Tk’ by David D. Levine, who appears very fluent across a multitude of SF subgenres. Writing somewhat in the mode of Jack Vance’s classic novella ‘The Moon Moth,’ Levine puts his harassed computer salesman up against insectoid beings with bizarre codes of decorum and business ethics, a language of custom and evasion the poor commercial traveler only slowly begins to fathom; the act of translation becomes a conceptual breakthrough, leading in an unexpected and yet curiously inevitable direction. One can speculate that Levine’s Walker is ultimately wiser in his choice of accomodation to the exotic than was Vance’s Edwer Thissell; but whatever the conclusion, ‘Tk’Tk’Tk’ is a skillful confection, another token of its author’s burgeoning virtuosity. … Recommended.” —Locus
“In the March Asimov’s I appreciated David D. Levine’s ‘Tk’tk’tk’, about a salesman struggling to stay afloat on an alien planet where the culture spins him so off-balance he finds himself re-orienting. Do you ever find out what ‘Tk’tk’tk’ means? Read it and you may see; sometimes you have to let go of your goals in order to accomplish them.” —Emerald City
“There is a sort of old-fashioned Orientalness to these aliens, which makes it fitting that Walker would be an old-fashioned travelling salesman. … But when Walker cracks the alien code, so to speak, it transforms more than just his mission. Levine brings in Eastern spiritual elements to give the story an added dimension: understanding the other as the key to understanding the self.” —The Internet Review of Science Fiction
“[T]akes a premise that seems very “Golden Age”… but gives it a very 21st-century sensibility. In the Golden Age, the salesman would have proved the superiority of Earth culture, or would have been shown to be venal and deserving of being bested, or something equally simplistic. Levine adds some layers to the story.” —MT VOID
“The alien world was vividly imagined, the holiday, everything. Anywhere Levine decides to take me, I’ll believe I’m there.” —Tangent Online
Walker’s voice recorder was a beautiful thing of aluminum and plastic, hard and crisp and rectangular. It sat on the waxy countertop, surrounded by the lumpy excreted-looking products of the local technology. Unique selling proposition, he thought, and clutched the leather handle of his grandfather’s briefcase as though it were a talisman.
Shkthh pth kstphst, the shopkeeper said, and Walker’s hypno-implanted vocabulary provided a translation: “What a delightful object.” Chitinous fingers picked up the recorder, scrabbling against the aluminum case with a sound that Walker found deeply disturbing. “What does it do?”
It took him a moment to formulate a reply. Even with hypno, Thfshpfth was a formidably complex language. “It listens and repeats,” he said. “You talk all day, it remembers all. Earth technology. Nothing like it for light-years.” The word for “light-year” was hkshkhthskht, difficult to pronounce. He hoped he’d gotten it right.
“Indeed yes, most unusual.” The pink frills, or gills, at the sides of the alien’s head throbbed. It did not look down — its faceted eyes and neckless head made that impossible — but Walker judged its attention was on the recorder and not on himself. Still, he kept smiling and kept looking the alien in the eyes with what he hoped would be interpreted as a sincere expression.
“Such a unique object must surely be beyond the means of such a humble one as myself,” the proprietor said at last. Sthshsk, such-a-humble-one-as-myself — Walker could die a happy man if he never heard those syllables again.
Focus on value, not price. “Think how useful,” he hissed in reply. “Never forget things again.” He wasn’t sure you could use htpthtk, “things,” in that way, but he hoped it got the point across.
“Perhaps the honored visitor might wish to partake of a cup of thshsh?”
Walker’s smile became rigid. Thshsh was a beverage nearly indistinguishable from warm piss. But he’d learned that to turn down an offer of food or drink would bring negotiations to an abrupt close. “This-humble-one-accepts-your-most-generous-offer,” he said, letting the memorized syllables flow over his tongue.
He examined the shopkeeper’s stock as it prepared the drink. It all looked like the products of a sixth-grade pottery class, irregular clots of brown and gray. But the aliens’ biotech was far beyond Earth’s — some of these lumps would be worth thousands back home. Too bad he had no idea which ones. His expertise lay elsewhere, and he was here to sell, not buy.
The shopkeeper itself was a little smaller than most of its kind, about a hundred forty centimeters tall, mostly black, with yellow spine-tips and green eyes. Despite its insectile appearance, it was warm-blooded — under its chitin it had bones and muscle and organs not unlike Walker’s own. But its mind and culture were even stranger than its disturbing mouth-parts.
“The cup of friendship,” the alien said, offering a steaming cup of thshsh. Walker suppressed a shudder as his fingers touched the alien’s — warm, covered with fine hairs, and slightly sticky — but he nodded politely and raised the cup to his lips.
He sipped as little as he felt he could politely get away with. It was still vile.
“Very good,” he said… | <urn:uuid:f1cd918f-76fd-4a81-a731-a9fd2378add8> | CC-MAIN-2017-04 | http://bookviewcafe.com/bookstore/book/tktktk/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560283008.19/warc/CC-MAIN-20170116095123-00079-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.961712 | 1,516 | 1.601563 | 2 |
Whether you are furloughed, laid off or fired, it hurts. It’s a blow to your ego, and losing a regular paycheck is a blow to your finances. Fortunately, for many it was temporary, and after the initial weeks and months of the pandemic they were able to go back to work.
If you were furloughed and your paycheck continued during your furlough (lucky you!) then your finances and taxes didn’t change much. But if you had a gap in pay, with a corresponding gap in taxes withheld, what does that mean for your overall tax picture for 2020?
If you received unemployment benefits during the period you weren’t working, those benefits are taxable, but income taxes weren’t withheld unless you made a special request. As a result, the taxes on those benefits are due when you file your tax return in the spring or will reduce the amount of your tax refund.
Speaking of refunds, the amount of your refund depends on how much was taken out of your paycheck for income taxes compared to the actual taxes on your tax return. If you had more taken out than the actual taxes, you are due a refund of the difference. But during the weeks or months you weren’t receiving a paycheck, nothing was taken out. That will result in a lower refund at 2020 year end.
There is one ray of sunshine in all of this. Our system of income taxes is graduated, with higher rates applying to higher income. If your income dropped for 2020, your tax bracket may have dropped as well, and that could increase your refund a bit. And now that your income is lower, that could make you eligible for tax credits that didn’t apply to you before, such as the Earned Income Tax Credit. | <urn:uuid:62199245-4f54-4fe2-821a-b1103d68e7a7> | CC-MAIN-2022-33 | https://blog.lonestarcu.org/page/3 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572212.96/warc/CC-MAIN-20220815205848-20220815235848-00466.warc.gz | en | 0.983282 | 368 | 1.921875 | 2 |
Somebody sent me this essay by George Monbiot. In a nutshell, he makes a case that the ultra-wealthy did not earn their wealth through hard work, enterprise or superior intelligence. Instead, they got where they are due to a combination of luck and psychopathic traits.
I must admit I was impressed by the following argument:
Such results have been widely replicated. They show that traders and fund managers across Wall Street receive their massive remuneration for doing no better than would a chimpanzee flipping a coin. When Kahneman tried to point this out they blanked him. “The illusion of skill … is deeply ingrained in their culture.”(2)
So much for the financial sector and its super-educated analysts. As for other kinds of business, you tell me. Is your boss possessed of judgement, vision and management skills superior to those of anyone else in the firm, or did he or she get there through bluff, bullshit and bullying?
But I am deeply suspicious of what the 99 percenters, and Mr. Monbiot, are trying to do. While it is true that, by most of our standards, the wealthiest people on Earth do not deserve their wealth, could it not also be said that the smartest people do not deserve their great intellect, with which they were born? Is it not also possible to claim that the most beautiful women do not deserve their beauty? That those born into loving, and intact, families, do not deserve such good fortune?
At its core, the 99 percenters seem to be upset that life is not fair – and that somebody should make it more fair. Who gets to decide whom, among the wealthy, deserve their wealth? By whose criteria? It is frightening to contemplate the answers to these questions – for images of the French, and Russian, revolutions come to mind.
I have little doubt that the 99 percenters would counter that I am missing the point. That most of us are being reduced to slavery by the one percent. I don’t see it that way. While I admit to having a certain amount of envy toward those whose incomes are measured in billions of dollars, the vast majority of people I know (here in American, at least) have vastly more wealth and freedom than 99% of their ancestors. Those protesters are part of the one percent and they don’t even know it! | <urn:uuid:81a0d041-fbd8-4653-aec5-b7655071d298> | CC-MAIN-2017-04 | https://jewamongyou.wordpress.com/2011/11/11/what-do-the-99-percenters-want/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280410.21/warc/CC-MAIN-20170116095120-00454-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.979877 | 487 | 1.546875 | 2 |
Global credit rating agency Moody's Investor Services on Monday said the Indian economic revival will likely to be shallow.
In its report, 'Coronavirus clouds growth outlook just as the economy showed signs of stabilization', Moody's said the economic revival of India is likely to be shallow.
"India's economy has decelerated rapidly over the last two years. Real GDP (gross domestic product) grew at a meagre 4.5 per cent in Q3 2019," Moody's said.
Improvements in the latest high frequency indicators such as PMI (Purchasing Managers' Index) data suggest that the economy may have stabilised, Moody's said.
While the Indian economy may begin to recover in the current quarter, it will be slower than previously expected, Moody's said.
"Accordingly, we have revised our growth forecasts to 5.4 per cent for 2020 and 5.8 per cent for 2021, down from our previous projections of 6.6 per cent and 6.7 per cent, respectively," Moody's said.
Pointing out that the revival of domestic demand - rural and urban, is key for economic momentum, the credit rating agency also said the resumption of credit growth is also important.
"As data from the Reserve Bank of India (RBI) shows, credit impulse in the economy has deteriorated throughout the last year as a result of the drying up of lending from non-bank financial institutions as well as from banks, Moody's said.
The rating agency also said Indian banks were not willing to lend and lower their lending rates despite rate cuts by the RBI.
"As a result, non-food bank credit growth decelerated to 7.0 per cent in nominal terms in December 2019, down sharply from 12.8 per cent a year earlier.
"The deterioration in credit growth to the commercial sector is particularly stark. Nominal credit to industry grew at only 1.6 per cent year-on-year in December 2019, while credit to the services sector registered 6.2 per cent nominal growth, and credit to agriculture and related activities grew 5.3 per cent," Moody's said.
On the impact of the deadly coronavirus spread from China, Moody's said it is still too early to make a final assessment of the impact on China and the global economy.
"We have revised our global GDP growth forecast down, and we now expect G-20 economies to collectively grow at 2.4 per cent in 2020, a softer rate than last year, followed by a pickup to 2.8 per cent in 2021," the rating agency said.
According to Moody's assumptions, the virus outbreak will cause disruption in Q1 economic activity.
"Under our baseline forecast, the spread of the coronavirus will be contained by the end of Q1, allowing for resumption of normal economic activity in Q2.
"At present, China's economy is by far the worst affected. However, the rest of the world also has exposure as a result of a hit to global tourism in the first half of this year and short-term disruptions to supply chains," Moody's said.
Moody's also said the effects on the global economy could compound if the rate of infection does not abate and the death toll continues to rise, because supply chain disruptions in manufacturing would become more acute the longer it takes to restore normalcy. | <urn:uuid:33ad0cca-6d07-47b1-97c4-5118c6e96acf> | CC-MAIN-2022-33 | https://www.thenewsminute.com/article/indian-economic-revival-likely-be-shallow-moodys-118327 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00266.warc.gz | en | 0.955014 | 692 | 1.882813 | 2 |
St. Charles has a population of 60,321 and is located in St. Charles county.
The average in-state tuition for full time undergraduate students in business administration schools in St. Charles during the 2009 - 2010 school year was $13,080.00. The average tuition was $13,080.00 for non-residents studying in Missouri.
The cost, on average, for books and supplies needed for business administration schools in St. Charles is $2,100.00. Students living on campus at business administration schools in St. Charles paid an average of $7,060.00 for room and board during the 2009 - 2010 school year. Students living at home incurred costs of $9,628.00. There is one business administration college in St. Charles. 13 students were reported to have graduated from business administration programs in St. Charles in the 2008 - 2009 school year.
|Profession||Average Salary||Number Employed in City|
|General and Operations Managers||$108,980.00||16,670|
|Administrative Services Managers||$76,360.00||2,130|
|Human Resources Managers, All Other||$111,220.00||570|
|First-Line Supervisors/Managers of Office and Administrative Support Workers||$50,190.00||11,710|
|Bill and Account Collectors||$30,590.00||5,790|
|Bookkeeping, Accounting, and Auditing Clerks||$34,740.00||16,250|
|Payroll and Timekeeping Clerks||$36,590.00||3,160|
|Loan Interviewers and Clerks||$33,560.00||2,410|
|Human Resources Assistants, Except Payroll and Timekeeping||$38,870.00||1,710| | <urn:uuid:542f3d32-f617-4d9b-9609-7dbd445f806a> | CC-MAIN-2017-04 | http://www.unixl.com/dir/business-administration/missouri/st-charles/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560285315.77/warc/CC-MAIN-20170116095125-00573-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.933296 | 395 | 1.53125 | 2 |
Malcolm Muggeridge: A Life
This biography of Malcolm Muggeridge traces the varied life of one of the most brilliant and controversial men of the twentieth century. The author, Ian Hunter, was given full access to all of Muggeridge's unpublished material, letters, and diaries. The result is an objective, well-researched, and honest account that is sometimes at variance with Muggeridge's own recollection of events. Ian Hunter captures the humor, the intellect, the rawness of perception, the abandoned honesty of a man engaged in knowing himself, his world, and his God. Malcolm Muggeridge was not merely a "vendor of words," as he invariably described himself, but was also a celebrated author, broadcaster, lecturer, debater, traveller, journalist and television personality, a one-time ardent admirer of the Soviet system, a World War II intelligence agent, and a former agnostic turned committed Christian. To many people, however, Malcolm Muggeridge was admired above all for his superb use of the English language. It is to the credit of Ian Hunter that after reading this biography one has a clearer understanding of an extraordinary man. Dr. Ian Hunter is professor emeritus at the University of Western Ontario. His articles and reviews have appeared in many Canadian and American poublications. He edited two collections of Muggeridge's writings: Things Past and The Very Best of Malcolm Muggeridge; he also wrote a biography of Muggeridge's friend, Hesketh Pearson (Nothing to Repent: The Life of Heskerth Pearson).
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actually Alec Vidler Alwaye Anthony Powell April asked Autumnal Face became become believe British broadcasting C. P. Scott called Cambridge Christian church Croydon Daily Telegraph death Diary editor England fact fantasy father February feel George Orwell Green Stick H. T. Muggeridge heart Hesketh Pearson hope Hugh Kingsmill human humor India January Jesus Rediscovered Kingsmill's Kitty Labour later leader letters living London looking Lord magazine Malcolm Muggeridge Manchester Guardian March memoirs mind morning Moscow Muggeridge to H. T. Muggeridge to Vidler Muggeridge wrote Muggeridge's never novel November occasionally October once Orwell paper play political prophet Punch religious replied Review Russian seemed September Soviet Union spent Statesman Street Sunday Pictorial talk Telegraph television thing thought Tide tion took truth turned walk Whatlington Winter in Moscow words writing | <urn:uuid:138f4835-83d5-448f-8113-89eba053b160> | CC-MAIN-2017-04 | https://books.google.co.uk/books/about/Malcolm_Muggeridge.html?id=oaEfbtzqEUwC&hl=en | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279933.49/warc/CC-MAIN-20170116095119-00129-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.952332 | 513 | 1.6875 | 2 |
With innovative board sports growing -- think snowboarding, wakeboarding, kiteboarding -- it makes sense that the granddaddy of them all wouldn't stand still. Skateboarding, developed in the 1950s among surfers who wanted to "surf the streets" in their spare time, is being influenced by its modern offspring. Novel new boards let you carve asphalt like it's powder, stand up and paddle like you're in Waikiki and twist like, well, nothing I've ever seen.
-- Roy M. Wallack
Paddle on pavement
Kahuna Creations Ki'i Pohaku longboard and Big Stick: A 4-foot longboard that you propel on the streets with a 5 1/2-foot, rubber-tipped wooden pole.
Likes: Exhilarating fun and fitness for all ages. Superb upper-body workout as you push off and glide; you drag the end of the stick to stop. The artistic, slightly rounded, sand-impregnated, three-eighths-inch-thick wooden board flexes as you push off, adding to your power. The 10-inch wide wheelbase keeps it very stable. Instant fun -- you can do it the first time and feel yourself getting smoother by the minute.
Price: Longboard, $139-$159; Big Stick, $89-$149 (877) 945-0100; www.kahunacreations.com.
Hone those surfer skills
Carveboard: Wooden-decked surf- and snowboard land trainer, invented for pro surfer Brad Gerlach by his father, Joe, that lets you simulate near-horizontal banking into a wave or snow with extra-wide wheelbase that enables the platform to pivot 45 degrees or more.
Likes: Great for fitness, skill-building, balance training and sheer fun. Starting on a slight hill and replicating the snowboarding position, with feet width-wise across the board, you squat, twist your torso and carve S-turns deeper and deeper. Although I'm not a surfer or snowboarder and was shaky at first, I got into a groove after about an hour and started seeing skills I didn't know I had. The huge 4-foot-long model with 9-inch-tall pneumatic Dragon Paw tires and the smaller 40-inch Longstik with polyurethane tires were great fun, with the former designed for steeper hills. Carving is work; I was soaked.
Dislikes: The wheels are so wide and stable that you can't kick up the board to your hands or spin it around.
Price: Wave, $450; Surfstik (34 inches), $275; Longstik (40 inches), $285. (760) 930-9767; www.carveusa.com.
A bit of twisted logic
The Wave: A 33-inch-long plastic two-wheel skateboard with duel foot platforms that twist in opposite directions, so you can power the board without setting foot on the ground.
Likes: Develops impressive balance and agility. Snaking along in an "S" pattern while keeping both feet planted on the concave platforms looks very, very cool.
Dislikes: Hard to learn. Frankly, trying to balance for a split second on the rotating castor wheels was too much for me, and I gave up. I didn't want to break my neck. But my extremely coordinated 11-year-old nephew, Jake, mastered the core twisting motion after 15 minutes.
Price: $129, DVD included. www.streetsurfing.com.
Tricked out on wheels
Flowboard: A 3 1/2-foot-long wooden board on 14 inline-skate wheels that are split into two curved rows, enabling you to rock deeply from side to side.
Likes: Fun for any age. Works the legs. Develops balance. Blends the feel and carving motion of a Carveboard snowboard/surf trainer with the agility of a regular skateboard. Start off riding as if on a regular skateboard, then place feet perpendicular to the length of the board and lean and twist to turn. You can kick up the board and do jumps and tricks. Very good control on hills; deep carving gets the outside wheels moving. Beginner-friendly.
Dislikes: Much slower and less smooth than the Carveboard. You can carve deep 45-degree turns, but it wobbles somewhat as you transition between the wheels.
Price: 32 inches, $80; 42 inches, $159. (800) 503-9432; www.flowlab.com.
Irvine-based endurance cyclist and runner Roy M. Wallack is the co-author of "Bike for Life: How to Ride to 100." Reach him at [email protected]. | <urn:uuid:cc37d388-410f-45aa-9201-83572b5f411d> | CC-MAIN-2017-04 | http://www.latimes.com/health/la-he-gear22-2008sep22-story.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280891.90/warc/CC-MAIN-20170116095120-00153-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.935143 | 1,021 | 1.742188 | 2 |
When it occurred on September 1, 2011, there was very little reporting on it. More than two weeks later, the NY Times is one of the few if only national media outlets to report on it. Yet, what happened that day has a profound effect on public safety, the quality of medical care patients receive and the public’s right to access information about physicians.
On September 1, 2011, the Health Resources and Services Administration (HRSA) removed the public’s access to the National Practitioner Data Bank. The public access file that was removed didn’t name physicians who’d been reported to their state medical boards because of alleged medical malpractice. It did however, serve as an informative source for the public and those interested in quality of care issues regarding how state medical boards deal with physicians who’ve been accused of medical errors and medical malpractice.
Jessica Wapner, a freelance writer whose works have appeared in the NY Times as well as Slate, wrote an informative piece on the controversy for her blog today. She gives the full history of the public use file as well as explores the various issues at stake. It’s well worth a read.
Regular readers of this blog will know where our firm stands on this and similar issues. In healthcare matters, information is key. When access to information regarding medical errors and medical malpractice is restricted, everyone suffers. This is not a good public policy move and should be reversed.
- Racial Disparities in Health Care - January 18, 2021
- New Hampshire Doctor Who Plead Guilty to Sexually Assaulting a Patient Sentenced 5-10 Years - September 10, 2019
- Unsolicited Patient Observations Help Identify Surgeons More Likely to Commit Malpractice - August 1, 2018 | <urn:uuid:9244233d-4f35-4a72-bad0-47d77364a17b> | CC-MAIN-2022-33 | https://www.arbd.com/federal-government-withdraws-publics-access-to-national-medical-malpractice-file/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570767.11/warc/CC-MAIN-20220808061828-20220808091828-00476.warc.gz | en | 0.964309 | 365 | 1.742188 | 2 |
In today’s crazily busy world the importance of making time for leisure is more vital than ever. Yet so many of us lack a talent for it. We are working longer hours, consuming more than ever before; technology erodes the work–life balance further; increasingly, people feel that only work gives existence meaning. In a world where time is money, what is the value of walking without purpose, socialising without networking, nesting when we could be on our laptops?
Robert Dessaix shows, in this thoughtful and witty book, how taking leisure seriously gives us back our freedom – to enjoy life, to revel in it, in fact; to deepen our sense of who we are as human beings. He explains how we can reclaim our right to ‘rest well’, and to loaf, groom, nest and play, as he looks at leisure from many angles: reading, walking, travelling, learning languages, taking siestas and simply doing nothing. The result is a terrifically lively and engaging conversation that reminds us that at leisure we are at our most intensely and pleasurably human.
Availability: In Stock | <urn:uuid:e9701dfe-efc2-4f51-addb-7d3b67b4ffb7> | CC-MAIN-2022-33 | https://www.alittleluxury.com.au/products/the-pleasures-of-leisure&cName=gifts-books_health_lifestyle&page= | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571198.57/warc/CC-MAIN-20220810161541-20220810191541-00270.warc.gz | en | 0.946985 | 231 | 1.703125 | 2 |
A listening Ncat may control which hosts connect to it with the
options. Each of these takes a comma-separated list of host
specifications. The syntax is almost identical to that recognized by Nmap for
(see the section called “Target Specification”).
This includes IPv4 and IPv6 addresses, hostnames, IPv4 octet ranges,
and CIDR netmasks. In Ncat (unlike Nmap), CIDR netmasks are supported for IPv6
--allow, any hosts matching one of the listed specifiers
are allowed and all others are denied. With
those hosts matching the list are denied and all others are accepted.
If a host matches both the
--deny lists, it is denied.
to allow or deny a list of host/network specifiers stored in a file. Each line of the
file contains a specification in one of the forms listed above. Any
file acceptable to Nmap's
options is suitable for
The following example commands demonstrate various kinds of access control.
- Allow one host, deny all others
ncat -l --allow 192.168.0.125
ncat -l --allow 2001:db8::7d
ncat -l --allow trusted.example.com
- Deny one host, allow all others
ncat -l --deny 192.168.0.200
ncat -l --deny 2001:db8::c8
- Allow hosts on a local network, deny all others
ncat -l --allow 192.168.0.0/24
ncat -l --allow 192.168.0.0-255
ncat -l --allow 2001:db8::/32
- Allow or deny hosts from a file
ncat -l --allowfile trusted-hosts.txt
ncat -l --denyfile external-hosts.txt
Be aware that host-based access control is susceptible to spoofing attacks and various other possible failures. These mechanisms should not be relied on for complete security.
Another kind of access control is simply limiting the maximum number
of connections a listening Ncat will accept. Use the
option or its
alias to do that. The default maximum number of connections is 100, or 60 on Windows. | <urn:uuid:71e93a76-09c9-4bef-9805-0611cd761035> | CC-MAIN-2017-04 | https://nmap.org/ncat/guide/ncat-access.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279189.36/warc/CC-MAIN-20170116095119-00061-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.742489 | 485 | 2.640625 | 3 |
The three buildings that have successively occupied the site between the Royal Arcade and Bath Place have over the years had more different uses than the buildings on any other site on Worthing seafront.
Today Connaught House stands there, with the Connaught Leisure amusement arcade on the ground floor and the Occasions night-club above.
The first building on the site, erected in 1797, was Wicks Original Royal Baths, a curious-looking wooden structure that jutted out from the line of the other buildings along the esplanade – as did its successor.
John Wicks’s baths were the first baths in Worthing, and they remained the only baths in the town until, in 1818, Thomas Trotter, the proprietor of the Theatre Royal in Ann Street, built the Royal Baths – a building later known as Marlborough House – some 230 yards to the west, on the corner of a street that no longer exists, called Paragon Street.
The erection of Worthing’s first bath-house was an important step in the transformation of the town from a straggling village to a thriving Georgian seaside resort, and in ‘A Guide to All the Watering and Sea-Bathing Places’, published in 1803, John Feltham writes: “The erection of a very commodious warm baths (Wicke’s [sic]) sufficiently prove how far Worthing has risen in public estimation.”
John Evans, author of ‘A Picture of Worthing’, published in 1805, gives a little more detail about Wicks’s bath-house: “There is also a warm bath, belonging to Mr John Wickes [sic]; it has been lately erected and is heated to whatever temperature may be required; thus the benefits of hot and cold bathing, so much insisted on by the faculty [that is, the medical profession] may be enjoyed in perfection.”
In the 1813 and 1817 editions of ‘A Sketch of Worthing’, John Mackoull provides one further detail, telling us that there were “five hot and cold baths” at Wicks’s establishment.
One notable visitor to Wicks’s‑ baths, eight years after it opened, was Jane Austen’s elder sister, Cassandra, who patronised it on September 20, 1805.
This was during her and Jane’s stay in the town at the end of 1805, which was later to provide the novelist with the inspiration for her final, unfinished novel ‘Sanditon’.
In 1829, the original bath-house was demolished, and replaced by a new building, which went under the grander title of the New Parisian Baths.
As part of the process, the proprietor, by now a man called Mark Markwick, was given permission to build a tank 17 feet by 12 feet in front of the building, under the seafront esplanade.
Markwick came to an unusual arrangement with the Town Commissioners – namely that “a cast iron tube to allow the escape of foul air” from the tank would also be “used by the Commissioners for a lamp post”!
Although the New Parisian Baths was presumably an improvement on its old-fashioned predecessor, it did not remain in business for long, closing after just eight years.
The building had a number of uses after that, including as a shop known as the Pier Bazaar; and this was its use when the etching and two of the photographs reproduced on these pages were first published.
The etching shows the building with a pitched roof, but this may have been artistic licence, since the two photographs of the same period do not have this.
The Pier Bazaar closed in 1888 and the building, by now numbered No. 35 Marine Parade, briefly became the Parade Restaurant.
Then, from 1891 to 1934, it was a gentlemen’s club called the County Club.
This seems to have been a provincial version of the gentlemen’s clubs to be found in the West End of London. It had a dining-room, and presumably a bar and a smoking-room.
There would probably have been a billiards room too, and possibly a library.
It has proved very difficult to discover anything further about the County Club – the fact that its secretary in 1910 was one H. N. Collet is not perhaps of overwhelming interest – and I would be glad to hear from anyone who knows anything more about it.
Perhaps the father or grandfather of a Herald & Gazette reader was a member, and sometimes spoke of it?
After the club closed in 1934, the building was demolished and replaced the following year by Connaught House, built in complementary style to the Royal Arcade, which had been erected ten years earlier on the site of the Royal Hotel.
Connaught House was the first building on the site to be in line with the other buildings on Marine Parade, rather than jutting out onto the esplanade.
• Antony Edmonds is the author of Jane Austen’s Worthing: The Real Sanditon (Amberley, 2013). The picture of Wicks Original Royal Baths is reproduced by courtesy of Worthing Museum and Art Gallery. | <urn:uuid:27a0082c-e1a4-4830-b8b6-3c673a8eabee> | CC-MAIN-2017-04 | http://www.shorehamherald.co.uk/lifestyle/wicks-original-royal-baths-and-the-county-club-1-6263044 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279489.14/warc/CC-MAIN-20170116095119-00006-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.977658 | 1,102 | 1.710938 | 2 |
If you are a runner on keeping your body fit, this article is for you. We, the treadmill users, often wonder what treadmill belts are made of. The vast majority of treadmill belts are made from PVC or polyvinyl chloride. This is the same material used in plumbing pipes and is very durable.
Some companies use a nylon-coated belt, which is more expensive but quieter and smoother than a PVC belt. If you’re looking for a top-of-the-line treadmill, you may find a belt made from silicone-coated fiberglass.
- 1 Types of Belts Available in the Market
- 1.1 PVC Treadmill Belt:
- 1.2 Nylon-Coated Treadmill Belt:
- 1.3 Silicone-Coated Fiberglass Treadmill Belt:
- 2 Which One Is Better?
- 3 Pro Tips on Belt Materials
- 4 Final Words
Types of Belts Available in the Market
Like other treadmill parts, such as a treadmill motor and treadmill deck, not all treadmills companies use the same belt. There are various types of belts in the market.
Depending on their manufacturing material and treadmill features like weight, difference, replace, soft, runners, surface, speed, rollers, durability, power, and form, we search a shortlist of them. As follows…
- Polyvinyl chloride (PVC)
- Nylon-coated belt
- Silicone-coated fiberglass
PVC Treadmill Belt:
Made from heavy-duty PVC, these treadmill belts are designed to withstand years of use. They’re also very affordable, making them a great option for budget-conscious shoppers. PVC belts are also quite durable, so you won’t have to replace them as often as other treadmill belts.
Benefits of a PVC Belt
The main benefit of a common belt is that it’s very inexpensive. This makes it a good choice for budget-conscious shoppers. Additionally, PVC is a strong and durable material that can withstand a lot of wear and tear. If you’re looking for a basic treadmill that will last for years, a PVC belt is a good option for a treadmill track.
Drawbacks of a PVC Belt
One of the main drawbacks of a common belt is that it’s not as smooth or quiet as other options. Additionally, PVC can be a bit stiff, making it uncomfortable to run on for extended periods.
Nylon-Coated Treadmill Belt:
These belts are made from PVC coated with nylon, making them more durable and smoother than traditional PVC belts. They’re also quieter, making them a good choice for people who don’t want to disturb the peace while working out.
Benefits of a Nylon-Coated Belt
The main benefit of a nylon-coated belt is that it’s more durable than a traditional PVC belt. The coating makes the belt smoother and quieter, which is a plus for anyone who wants a more comfortable workout.
Drawbacks of a Nylon-Coated Belt
Nylon-coated belts are more expensive than traditional PVC belts, so they may not be a good option for budget-conscious shoppers. Additionally, the coating can make the belt slippery, which may not be ideal for people who have a lot of experience running on treadmills.
Silicone-Coated Fiberglass Treadmill Belt:
Made from strong fiberglass coated with silicone, these treadmill belts are designed to withstand years of heavy use. They’re more expensive than other options but also the most durable.
Benefits of a Silicone-Coated Belt
The main benefit of a silicone-coated belt is that it’s incredibly durable. This is a good option if you’re looking for a treadmill that will last for years. The silicone coating makes the belt smoother and quieter than other options.
Drawbacks of a Silicone-Coated Belt
Silicone-coated belts are more expensive than other options, so they may not be a good choice for budget-conscious shoppers. Additionally, the silicone coating can make the belt slippery, which may not be ideal for people who have a lot of experience running on treadmills.
Which One Is Better?
So, there you have a brief summary, depending on its price, companies, walking force, quality, and brand. These are the most common materials used to make treadmill belts. If you’re looking to purchase durable and affordable equipment for your home or gym, PVC is the way to go.
For a smoother and quieter ride, opt for a nylon-coated belt. And if you’re looking for the most durable option, choose a silicone-coated fiberglass belt. Those are the informed decision you should know as a treadmill user for exercise and backing.
Pro Tips on Belt Materials
If you are in doubt, our team of experts can help you choose the best treadmill belt for your needs.
- If you’re on a tight budget, PVC is a good option. If you’re willing to spend more, nylon-coated belts are a good choice. And if you’re looking for the most durable option, silicone-coated fiberglass belts are the way to go.
- For a smoother and quieter ride, opt for a nylon-coated belt.
- And if you’re looking for the most durable option, choose a silicone-coated fiberglass belt.
No matter which type of treadmill belt you choose, ensure it’s the right size for your machine. Additionally, read the manufacturer’s instructions carefully to ensure that you install the belt correctly. With a little care and maintenance, your treadmill will provide years of enjoyment.
We hope this blog post helped you understand the different treadmill belts on the market. If you have any questions, please feel free to contact us.
Thanks for reading! | <urn:uuid:0b3889dc-9ca5-4301-97d1-20615244ee86> | CC-MAIN-2022-33 | https://iwassweet.com/what-are-treadmill-belts-made-of/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572304.13/warc/CC-MAIN-20220816120802-20220816150802-00466.warc.gz | en | 0.939353 | 1,242 | 1.960938 | 2 |
What Are The Improvement Options Of Matlab Simulation Assignment Help?
MATLAB simulation plays an important part in the study and creation of complex systems, innovative products, and innovative processes. It saves time for product development, and helps to quantify the operation of the system. As a user, you can create complex problems with mathematical expressions, and then run the software to evaluate the effects of your solution. You can even simulate business processes and run them on your personal computer.
Matlab is the best tool for all types of MATLAB Users. The following are some of the matlab simulation speed enhancements that can help you create more efficient programs. This will enhance the quality of your generated code, saving you time, effort, and money.
Faster image processing – Speed up your image processing by adjusting the image blurring, depth of field, and motion blur settings. There are some image processing techniques which can produce good quality images using MATLAB. However, the image processing algorithm can become slow when some of these techniques are not applied. To improve the quality of the generated code and save more time for your project, you need to adjust these settings.
Faster performance – Improve your matlab simulation results by removing extraneous parameters from the simulation. Excess parameters will slow down your process and make the generated code heavier. You can remove or change the external variables, which can make your code more readable and reduce the pattern space of the generated code. If your external variables do not fit the pattern, it will produce incorrect results. You can also remove any other unwanted parameters which are unnecessary for your application.
Better performance – MATLAB users can use matlab support and plug-ins which have matlab file help feature. There are also some tools and applications which are available at your local office store such as mlispace, rltools, mplustracker etc. They are helpful to improve the performance and scalability of your simulation. However, the users should use the latest release of these tools to get the best performance. These matlab file help tools are not included in the free version of matlab.
More accuracy – A matlab coder can provide faster simulation results by reducing the non-essential parameters. The best quality matlab codes are written in the original format which is easily readable by any user. Most of the matlab users prefer to use matlab coder which has similar interface and readability. Hence, the matlab coder must support fast reading and writing of matlab codes. It should provide high level of accuracy so that you do not need to spend time in reading and re-reading the same code again.
Faster delivery – Matlab also provides higher quality output by utilizing the latest algorithms and techniques. These make the simulation process quite fast. Moreover, the latest features and functions are received signal by the matlab interface with almost zero waiting time. There is no difference between the received signal and the output of matlab code. If you want to do more calculations, then you may need more time.
Faster computations – A good matlab simulation tool also reduces the time spent on initializing and running the application. Sometimes, it can take some time to initialize an application and run it. But when a user uses a good software, he/she does not need to wait for long time to compute the sums, averages, etc. By utilizing the latest methods and techniques, the time taken to run the application is reduced by almost 50%.
Faster results – In matlab, nearly every operation can be run multiple times. If more time is needed to compute certain functions, then you will receive slow results. But with the latest versions of matlab, one can obtain faster results with smaller amounts of calls. For instance, if the sum of the squares of the radii is needed, then you can compute it many times without wasting too much time. In other words, the number of calls to the functions is minimized, thus increasing the simulation speed.
Better accuracy – Using the latest versions of matlab, one can easily detect the non-zero values and signals. Previously, the signals were calculated based on the known values of the random numbers. However, this sometimes made the computations inaccurate. Therefore, the new version increases the precision of the numerical output by properly detecting the numeric alpha, and avoiding the use of zero-phase outputs.
More robust results – During the course of the Matlab simulation, a variety of parameters are used. However, they are all being used in a closed environment, which makes the simulation vulnerable to the effects of external interferences. Therefore, using Matlab, more robust results can be obtained. This is because the experimental data is not leaked out into the real world, limiting the freedom of the researchers. | <urn:uuid:5d20dd2d-fa57-4785-85cd-61cc8b453dfb> | CC-MAIN-2022-33 | https://www.matlabhelponline.com/matlab-simulation-19580 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00267.warc.gz | en | 0.921792 | 970 | 1.984375 | 2 |
From UC Berkeley's Webcast series, Michael Pollan, UC Berkeley Professor of Journalism, discusses his new book, The Omnivore's Dilemma: A Natural History of Four Meals. "What should we have for dinner? According to Michael Pollan the answer may determine our survival as a species." The first blurb on the role of corn is fascinating.
Whole Foods has made nice with Pollan in another UC webcast with powerful content on food production. By the way, Whole Foods has their own video blog called Secret Ingredient.
Food choice connects to deeper questions involving complex systems, risk perception, ecosystem sustainability, and democratic control over technology, some of which were discussed at a Pew Initiative on Food and Biotechnology by Edward Woodhouse (QT) of Rensselaer Polytechnic Institute. As a reminder, stay away from current batches of Chinese toothpaste and other possible sources of additives that the FDA is having trouble evaluating. | <urn:uuid:69095378-b7d4-4cdb-9f3c-ca2deee35895> | CC-MAIN-2017-04 | http://aeportal.blogspot.com/2007/06/pollan-depending-on-corn.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280791.35/warc/CC-MAIN-20170116095120-00363-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.951124 | 196 | 2.3125 | 2 |
Children will love this wonderful tale of a crow who spies two fresh eggs in a nest belonging to Hooty the Owl and Mrs. Hooty. Does Blacky snatch those delicious eggs? Filled with humor and important lessons about nature and wildlife. Reset in large, easy-to-read type. 4 original illustrations by Harrison Cady.
To view this DRM protected ebook on your desktop or laptop you will need to have Adobe Digital Editions installed. It is a free software. We also strongly recommend that you sign up for an AdobeID at the Adobe website. For more details please see FAQ 1&2. To view this ebook on an iPhone, iPad or Android mobile device you will need the Adobe Digital Editions app, or BlueFire Reader or Txtr app. These are free, too. For more details see this article.
|Size: ||1.4 MB|
|Publisher: ||Dover Publications|
|Date published: || 2014|
|ISBN: ||9780486110868 (DRM-EPUB)|
|Read Aloud: ||not allowed| | <urn:uuid:bf107fa3-e129-4abc-92c3-63e9502c42e7> | CC-MAIN-2017-04 | http://www.lybrary.com/blacky-the-crow-p-651162.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279933.49/warc/CC-MAIN-20170116095119-00123-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.829296 | 229 | 2.03125 | 2 |
Following on from a report regarding yet another exploding Galaxy Note 7, which this time is believed to be responsible for burning down a home in Horry County, South Carolina, and another case of a Jeep Cherokee being burned down, the Federal Aviation Administration (FAA) has issued an official warning over the use of Samsung Galaxy Note 7 handsets on airplanes.
Samsung’s worldwide recall of Galaxy Note 7 hardware has come off the back of a number of incidents around the world whereby devices have been exploding whilst on charge.
Some of those incidents have been relatively low-key, causing little damage to property or person, whereas others, like the aforementioned incident in South Carolina and the burning of a vehicle, has resulted in substantial damage to property. In light of this, the FAA has warned against turning on or charging a Galaxy Note 7 during the course of flights:
In light of recent incidents and concerns raised by Samsung about its Galaxy Note 7 devices, the Federal Aviation Administration strongly advises passengers not to turn on or charge these devices on board aircraft and not to stow them in any checked baggage.
Samsung is in the process of recalling all 2.5 million devices sold worldwide, and even though the recall wasn’t actually issued through the Product Safety Recall Commission, which would have resulted in an immediate airline ban in the United States, the FAA clearly sees enough potential for issue to send this official warning. It’s also very notable that three individual Australian airlines have already taken their own initiative to ban the use or charging of the Note 7 on their flights.
The recall and exchange is undeniably the right approach for Samsung, but with each device costing around the $850 mark, Samsung has already seen approximately $7 billion wiped off its share value due to negative market reaction to the incident.
If you own one of those Galaxy Note 7 devices, it’s worth erring on the side of caution and returning it back to Samsung. For information on how you can do that, check here: Galaxy Note 7 Recall: How To Return It To Verizon, T-Mobile, Samsung, Others.
(Top Image: Exploding Galaxy Note 7 causes $1,380 worth of damage to hotel room)
You may also like to check out:
- iPhone 7 Plus Vs Galaxy S7 Edge Vs Note 7 [Specs Comparison] | <urn:uuid:e043e2e0-ff64-4715-80b7-91b1ab856fdb> | CC-MAIN-2016-44 | http://www.iphonefirmware.com/faa-concerns-standard-notice-for-guests-to-not-utilize-or-provide-universe-note-7-on-routes/ | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988722459.85/warc/CC-MAIN-20161020183842-00345-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.943906 | 474 | 1.8125 | 2 |
A/C Clutch Relay Questons
b.benz at charter.net
Tue Mar 30 09:22:54 EST 2004
You're doing good Tom!
The diode is necessary to provide a suppression path for the inductive
energy stored in the compressor clutch coil when the relay contacts open.
If it fails shorted the compressor runs all the time, your case. If it
fails open, this stored inductive energy will cause a voltage spike on the
electrical system that may be K volts and will blow electronics like your
ECU and will be heard on the radio. Don't run the AC without this diode!
Use the 3A diode, it must be capable of handling the full clutch current at
the instant that the contacts open. The cathode must be to the + supply
relay contact such that it will not conduct normal current to the clutch.
If you get it in backwards it will act just like your shorted diode.
Good luck, Bernie
> From: TooManyAudis at aol.com
> I evac'd and recharged the a/c system on my 200q yesterday. All works well,
> with the climate control doing everything right (airflow goes to the proper
> vents and everything!), except that the compressor runs on econ and off. In
> searching the archives, the likely cause was a shorted diode that connnects
> between #30 and #87 on the relay. Sure enough, there was continuity between
> two pins, and when I cut one of the diode leads, the relay acted "normally"
> being open in the normal condition and continuity between the two pins when I
> manually closed the relay.
> So far, so good. One of the writeups mentioned replacing the defective diode
> with a Radio Shack 50v 2Amp diode. That would be fine, except my radio shack
> only had 1 amp and 3 amp diodes from which to choose. So, I got one of each.
> The question is, which one to use? I am thinking the 3 amp, but I will defer
> to those more knowledgeable on the topic. Also, the diode is directional.
> What is the proper orientation?
> This will be the first time doing a hack job on a circuit board, although I
> have done the basic soldering for universal oxygen sensors many, many times.
> Any tips for soldering/unsoldering?
> -- Tom
> 91 200q
> 88 80q
> 92 VW Cabriolet
> 200q20v mailing list
> 200q20v at audifans.com
More information about the 200q20v | <urn:uuid:558a3979-de8c-4a5c-a3ca-253843cc6b1d> | CC-MAIN-2017-04 | http://www.audifans.com/pipermail/200q20v/2004-March/017653.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560283008.19/warc/CC-MAIN-20170116095123-00087-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.893365 | 578 | 1.898438 | 2 |
I have seen your postings and I know you are the one to ask. PLEASE help me with my Atahualpa Header.
All the forums messages I have read pertaining to this say where the header files are. I am not understanding HOW to actually get there. I am a total novice and I have learned everything on my own, but this I can't figure out.
My site is xxxxxxxx.com. PLEASE walk me through the instructions on how to get in and do a custom header.
I will be happy to make a donation for your time. THANK YOU!
your site is hosted on a computer somewhere (godaddy, yahoo, westhost etc) and you have a folder on that computer, we will call it 'yourfolder' (the name depends on the host), so you have:
Inside that folder is a folder with all the wordpress code
and inside that is a folder called 'wp-contents'
and inside that is a folder called 'themes'
and inside that is 'atahualpa'
and inside that is 'images'
and inside that is a folder called 'header'
and that is where you put your header images.
So the question becomes, how do you get them there?
In order to transfer a file from one computer to another on the internet you use the 'file transfer protocal' or as it is commonly referred to as FTP. There are literialy hunderds of FTP programs out there and some host providers have them built-in to their control panels. (look for something saying FTP)
If you use a standalone FTP program you have to have some information
1) the name of your FTP server
2) your userid at your host
3) your password
all of these should have been given to you by your host provider, probably in an email.
Once you get connected to your host, via a standalone program or the host's control panel, you just move your way thru the folders till you get to:
here you will see three images that came with the install. You see/hear about two terms when using FTP: upload and download. The way to think about this is the host is at the top of a big hill and your computer is at the bottom. If you want to move (or put) a file from your computer to the host, you have to UPLOAD it (it goes up the hill) and if you want to get something from the host , you will DOWNLOAD it (it comes down from the top of the hill)
Without knowing the exact host and logging into it, I can't tell you the exact way it will work, because everyone seems to do it differntly. Same goes with FTP programs.
I use westhost.net as my provider and I'm on a mac and use a program called 'Fetch' to do my FTPing, so if you are on a mac, get that program, and are a westhost client, I can give you detailed steps but otherwise I can't | <urn:uuid:815aacea-e1fe-489d-92cb-10e5bd323380> | CC-MAIN-2017-04 | http://forum.bytesforall.com/showthread.php?p=20899&mode=threaded | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560284405.58/warc/CC-MAIN-20170116095124-00043-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.935153 | 632 | 1.585938 | 2 |
In an interview on CNN's "State of the Union" Cosby said "when a person has a gun sometimes their mind clicks that this thing will win arguments and straighten people out and in the wrong hands and wrong mind, it's death, it's wounding people."
He said he wasn't opposed to people having guns in their own homes, but not on the streets.
Cosby added "when you tell me you're going to protect the neighborhood that I live in, I don't want you to have a gun. I want you to be able to see something, report it and get out of the way. Because you are part of the neighborhood I don't want you to get hurt and I don't want you to hurt anyone."
According to 911 tapes from the night of the incident, Zimmerman told the 911 dispatcher that he was following Martin and continued to do so even though the dispatcher told him to stop.
Cosby said he used to own a gun but no longer does, according to the Associated Press, and that people should be taught to use every possible alternative before shooting someone.
Cosby told NBC the real issue is "about guns in our country," why Zimmerman had a gun, and who taught him how to use it.
"When you have a gun, you may not realize it, but you put it on your person and you mean to pull this," Cosby told NBC's Meet the Press, motioning with his trigger finger, "and kill somebody. That's what you mean to do." | <urn:uuid:1e421810-529c-4412-bce1-af5a9044fb3f> | CC-MAIN-2017-04 | http://m.boiseweekly.com/boise/bill-cosby-trayvon-martin-case-is-about-guns-not-race/Content?oid=2637215 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560282926.64/warc/CC-MAIN-20170116095122-00402-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.987089 | 310 | 1.609375 | 2 |
Scopul nostru este sprijinirea şi promovarea cercetării ştiinţifice şi facilitarea comunicării între cercetătorii români din întreaga lume.
Autori: McGregor, Helen, Evans, Michael, Goosse, Hugues, Leduc, Guillaume, Martrat, Belen, Addison, Jason, Mortyn, Graham, Oppo, Delia, Seidenkrantz, Marit-Solveig, Sicre, Marie-Alexandrine, Phipps, Steven, Selvaraj, Kandasamy, Thirumalai, Kaustubh, Filipsson, Helena and Ersek, Vasile
Editorial: Nature Geoscience, 8, 2015.
The oceans mediate the response of global climate to natural and anthropogenic forcings. Yet for the past 2,000 years — a key interval for understanding the present and future climate response to these forcings — global sea surface temperature changes and the underlying driving mechanisms are poorly constrained. Here we present a global synthesis of sea surface temperatures for the Common Era (ce) derived from 57 individual marine reconstructions that meet strict quality control criteria. We observe a cooling trend from 1 to 1800 ce that is robust against explicit tests for potential biases in the reconstructions. Between 801 and 1800 ce, the surface cooling trend is qualitatively consistent with an independent synthesis of terrestrial temperature reconstructions, and with a sea surface temperature composite derived from an ensemble of climate model simulations using best estimates of past external radiative forcings. Climate simulations using single and cumulative forcings suggest that the ocean surface cooling trend from 801 to 1800 ce is not primarily a response to orbital forcing but arises from a high frequency of explosive volcanism. Our results show that repeated clusters of volcanic eruptions can induce a net negative radiative forcing that results in a centennial and global scale cooling trend via a decline in mixed-layer oceanic heat content. | <urn:uuid:79a2dff5-4671-4f8e-9283-c68c498dbfd6> | CC-MAIN-2017-04 | http://ad-astra.ro/2016/04/15/robust-global-ocean-cooling-trend-for-the-pre-industrial-common-era/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281419.3/warc/CC-MAIN-20170116095121-00486-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.812964 | 428 | 2.375 | 2 |
Travel and shopping have become synonymous with this time of year. Trying to juggle working and year-end deadlines with buying gifts and visiting family and friends, often leaves people exhausted. Looking for short-cuts to getting all your items on your list checked off? You may want to slow it down a bit and make sure you aren’t falling for scams or worse, some activity that compromises your personal identity.
While reading a recent issue of Fraud magazine, I was astounded at the level some folks will go to make money off of the average consumer. Not that one would actually expect to find happy stories in such a magazine. To make things worse, some of the scams have been happening for quite some time. Hey, it worked in the past, people forget, so why not try it again? Being aware during the holiday craziness is your best defense. Here’s some of the schemes that really irked me (and I am sure many of you sadly have other tales of woe):
Buying for your favorite pet:
These days, it’s easy to create a label on a printer and produce packaging that looks like the real thing. Recently, another scam came up where the vendors were smuggling in fake flea and tick medication that was sold mostly online under popular brand names. Fluffy unfortunately cannot tell you if the medicine tastes different or is not working as well. The FDA has published on their website that “there are Internet sites that represent legitimate pharmacies” and that “If you are ordering pet medications online, you should look closely to ensure that you’re ordering from a reputable pharmacy.”
Buying food items such as Extra-Virgin olive oil (EVOO):
This one really hit home. My husband and I have traveled to Italy and Spain and like to think we are discriminating consumers who know what brands to purchase and can tell the difference in taste. We like to cook and we use a lot of EVOO, and often look to buy big containers at a good price. After reading about reports of contaminated or adulterated EVOO, I am not so sure that what we have been using is totally the real thing. The International Olive Council website has everything you want to know about olive oil including the legal definitions for the various types of olive oils. Some of the additives found in EVOO have been other oils such as soybean, corn, and sunflower. What really got me is that they found oils from hazelnuts and peanuts, both high-allergy products. The North American Olive Oil Association (NAOOA) conducts the nation’s largest olive oil testing and certification program, and provides a list of brands that agreed to product testing at least twice a year, for quality as well as purity.
Making charitable donations:
Our firm works with many non-profit organizations in the Metropolitan area and we truly care about the ability of these organizations to be able to collect donations so that they can fulfill their missions. With the end of the year approaching, many consider making donations in order to claim a charitable deduction on their tax return. With countless organizations asking for support, especially in the wake of the recent hurricanes, giving to legitimate organizations for legitimate causes may not be as simple as it seems. The Federal Trade Commission (FTC) has a website for consumer information and notes “do your research to avoid fraudsters who try to take advantage of your generosity” and provides tips to help make sure that the charitable contributions actually go to the cause you support. Sources to check out a charity include Better Business Bureau Wise Giving Alliance, Charity Navigator, Charity Watch, GuideStar, IRS Search for Tax Exempt Organizations, and National Association of State Charity Officials. If you are donating online, make sure that the website is the official website, and that SSL (secure sockets layer) encryption installed. The site’s URL will start with HTTPS:// (instead of just HTTP://) and an icon of a locked padlock will appear, typically in the status bar at the bottom of your Web browser. PayPal is generally a safe method for making online payments/contributions (however, see next bullet).
Clicking on Email links:
Nothing is sacred. You get an Email with a link to on a holiday greeting. Or you get an email from your bank requesting you confirm your information as part of a security review. Beware of the ever-present Email phishing scams. Also on the FTC’s Consumer Information website, is information about email phishing scams and offers practices to reduce your risk of being scammed. “Phishing scammers make it seem like they need your information or someone else’s, quickly – or something bad will happen. They might say your account will be frozen, you’ll fail to get a tax refund, your boss will get mad, even that a family member will be hurt or you could be arrested. They tell lies to get to you to give them information.” If you click or respond, the damages can be extensive. The scammers go to great lengths to mimic the look and feel of the company that is asking for your info or requesting you to simply click on a link. Hot off the press is an Email scam that is very sophisticated and actually comes from an official PayPal source. The Email informs users about a change in their “billing information” and directs the user to click on a link if the user did not make the supposed change. The link then takes the user to a fake login page that looks just like an official PayPal web page. PayPal recommends that if you cannot tell if the email is real or fake, then go directly to their website, and login to check its resolution center, where you will see a verified green signature on the web address. When in doubt don’t click and check directly with the company or the person sending you the email to ensure it is valid.
Using public charging stations:
You are out and about running all kinds of errands, or you are traveling, and your phone needs to be charged but your charger is nowhere near where you are. You may be tempted to use a public charging kiosk. Let your battery run out. It doesn’t matter what type of phone you have as they all allow the power supply and data stream to pass over the same cable. That means the cable is used not only to recharge your battery but also to transfer and sync your data. By plugging in someone else’s USB, you may be allowing that user to inject malicious code onto your device and steal your data. You don’t know what the other end of the cable is plugged into. This is known as Juice Jacking. Nope, not a new fad liquid diet. Since smartphones are really mini hand-held computers that also happen to make phone calls, almost all of us have personal identifying information stored on our phones that can be very attractive to cybercriminals. And don’t forget about tablets as the same rules apply. Keep your devices charged, carry your charger with you, carry a backup power charger, and avoid using public USB chargers. If you need to use a public charger, make sure that you are directly plugged in (use the AC/DC charger). Also consider using your phone’s security features as many have the ability to request your permission to transfer data or not if your phone is connected to a USB cable.
Getting to the holidays and year-end can be stressful enough. A little bit of vigilance and acumen can help you to enjoy the holidays. From all of us at Cerini & Associates, wishing you a safe and joyful holiday season and a very happy New Year.
Shari Diamond, CIA
Shari has been with Cerini & Associates, LLP since 2008 where she works primarily with the firm’s school district clients providing internal audit and claims audit services. She has over twenty years’ experience performing internal audits, risk assessments, and compliance reviews, as well as recommending processes to strengthen the internal controls environment while increasing efficiencies. Her prior experience at PWC and Northrop Grumman included performing Information Technology audits. | <urn:uuid:cd28d445-6b21-4bd4-b7d1-ea5642e38e49> | CC-MAIN-2022-33 | https://ceriniandassociates.com/wonderful-time-year-not-scammed/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570741.21/warc/CC-MAIN-20220808001418-20220808031418-00072.warc.gz | en | 0.955478 | 1,672 | 1.546875 | 2 |
Free UK Genealogy provides free, online access to family history records. We work with a team of dedicated volunteers to create high-quality transcriptions of public records from governmental sources, parish churches, and other trusted institutions. We believe that Open Data and Open Source are key to making and keeping public records accessible to all. We work with others with the same concerns.
Visit our project websites to search our records:
marriages and deaths | <urn:uuid:3786cf4b-244c-46ac-80ca-8c20790ada17> | CC-MAIN-2022-33 | https://www.freeukgenealogy.org.uk?r=194975644&d=bmd_1361186159 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571719.48/warc/CC-MAIN-20220812140019-20220812170019-00273.warc.gz | en | 0.93173 | 96 | 1.625 | 2 |
by PF Louis
(NaturalNews) Perhaps there is no beverage studied for health benefits more than green tea. It has been established as having anti-aging properties, promoting cardiovascular health, protecting against diabetes, reversing chronic fatigue syndrome, and exhibiting anti-cancer properties.
The major active ingredient that provides all these benefits is ECGC or epigallocatechin gallate, a type of flavonoid in green tea known as a catechin. It’s those catechins that are responsible for a multitude of health giving properties.
So many that ECGC extracts are sold for those who can’t drink all those cups of green tea that will do the trick. ECGC supplements have also been used as adjuncts to conventional cancer treatments.
The only caveat for ECGC supplements or heavy green tea consumption comes with pregnancy. Pregnant women who do either are at risk for the flip side of ECGC’s anti-cancer properties, leading to carcinogenic dangers.
And her newborn is at risk for childhood malignant central nervous system tumors if her polyphenol flavanoid intake is high. Best to avoid either green tea or ECGC extracts during pregnancy.
But for everyone else, ECGC catechin extract supplements or heavy green tea drinking is fine. Black tea doesn’t contain nearly the same catechin content as green tea.
Defeating dementia before it occurs
A recent study documented in the Journal of Biological Chemistry has determined that EGCG is able to stop amyloid-beta proteins from attaching to and killing brain cells in a lab setting. These amyloid-beta proteins are considered a leading contributor to Alzheimer’s disease.
This particular study, was done in vitro, which means in glass petri dishes or test tubes, but not in animals or humans. The study was performed by a research team at the University of Leeds in the UK. One of the researchers, Professor Nigel Hooper, claimed the study as an “important step in increasing our understanding of the cause and progression of Alzheimer’s disease.”
Other neurodegenerative diseases can be nipped before they are taken over by ECGC’s chelating properties to help eliminate iron or aluminum from the central nervous system and brain.
One beverage or extract for several health situations
Most green tea epidemiological studies, statistical analysis of a broad population over time, involve green tea intake. Many were in Japan. The best results were among those who drank five or six cups daily. That’s a lot of tea for Americans. But keep in mind that traditional tea cups in Japan or China are smaller than our coffee mugs, usually two to four ounces.
But if you want to make sure you get the benefits without drinking a few cups of green tea daily, EGCG supplements are available. Why should you bother? Here’s a list of health benefits from green tea’s ECGC:
* Promotes weight loss
* Reverses coronary artery disease
* Enhances functional capacity for senior citizens
* Helps relieve chronic fatigue
* Induces programmed cancer cell apoptosis (cell death)*
* Helps minimize HIV viral loads
* Offers protection against chronic inflammation
* Helps avoid autoimmune disease
* Boosts immune system as an antioxidant
* Protects against Alzheimer’s and other forms of dementia
*By the way, apoptosis is normal for healthy cells, they are programmed to die and be replaced by new cells. But cancer cells need to be killed by the immune system’s protease enzymes or externally supplied proteolytic enzymes or other cell-destroying agents like amagdylin from apricot seeds. Inducing apoptosis in cancer cells programs them to self-destruct instead of proliferate indefinitely.
That’s a lot of health from one type of beverage or its active ingredient extract ECGC. It is available at reasonable prices at most health food stores or online. | <urn:uuid:21547ade-850b-4778-88b0-b3c12c490e27> | CC-MAIN-2022-33 | https://dev.ironmagazine.com/2013/another-reason-to-drink-green-tea-greatly-reduce-your-risk-of-alzheimers/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573533.87/warc/CC-MAIN-20220818215509-20220819005509-00276.warc.gz | en | 0.931649 | 819 | 2.640625 | 3 |
Walking through the chaotic and vibrant streets of downtown Rangoon, now called Yangon, it is easy to be whisked away by the romance of a bygone era where the city was a heartbeat of the British Empire. Many of the once stately red colonial brick facades that once housed the administrative power of British Burma are now cloaked in shades of green mold and ferns after generations of neglect.
Nearby to downtown, the decadent roman column strewn halls of the remains of the now-abandoned British Pegu Club are wrapped in cobwebs. The ballroom that once hosted British royalty is now locked away from visitors. Inside the empty corridors of the clubhouse and hotel, the ghosts of a glamorous past are seen in a marble spiral staircase, teak floors and old telephone outlets.
Throughout the city, buildings built over the past two centuries including dispensaries, movie theaters and government halls that made up old Rangoon are still as important to the 5 million inhabitants of the city as ever before, serving as makeshift homes for families and businesses.
A new book, Relics of Rangoon for the first time profiles through in-depth research and photography the inside and out of more than 200 of the city’s architectural gems.
The book will be the culmination of over two years of research with a team of more than eight researchers, over 8,000 photographs, hundreds of hours of interviews with custodians, trustees, government officials, custodians, architects and conservation experts, and documentation research in the Myanmar National Archives.
Relics of Rangoon has already received wide praise from historians and critics alike who hail the project not only for the plus 700 photographs within, but as a first time look into the history of some of the city’s most overlooked buildings.
To learn more about the book or to buy a copy online, visit the project’s website at www.relicsofrangoon.com. | <urn:uuid:ac629f0b-b364-4d62-8c1e-144cdedc3df7> | CC-MAIN-2017-04 | http://thediplomat.com/2016/07/relics-of-rangoon/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280835.22/warc/CC-MAIN-20170116095120-00052-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.944231 | 401 | 2.578125 | 3 |
Intelligence sources said that the country halted a nuclear arms research programme in 2003 which allowed it to create weapons-standard uranium. They said that Iran could feasibly make a bomb within a year on an order from its leader, Ayatollah Ali Khamenei.
A US National Intelligence Estimate two years ago concluded that Iran had ended the programme because of a threat to invade Iraq by America.
But the intelligence sources told The Times today that Tehran had in fact stopped the research because it had achieved its goal.
Iranian military scientists had found a way of detonating a warhead that could be launched on its long-range Shehab-3 missiles, the sources said.
They added that it would take six months to enrich enough uranium and another six months to assemble the warhead, should Ayatollah Khamenei give the go-ahead.
The Iranian defence ministry has been running a secret nuclear research department for years. It employs hundreds of scientists and researchers, in a programme costing billions of dollars, to develop technology alongside the civilian nuclear programme.
The sources said: "If the Supreme Leader takes the decision [to build a bomb], we assess they have to enrich low-enriched uranium to highly-enriched uranium at the Natanz plant, which could take six months, depending on how many centrifuges are operating. We don't know if the decision was made yet."
Iran could have created smaller, secret facilities, away from those at the heavily guarded bunker in Natanz province, to develop materials for a first bomb, The Times says.
International Atomic Energy Agency inspectors only track nuclear material produced at monitored sites, and not the number of centrifuges that Iran has built.
Washington has given Iran until next month to start talks on its disputed nuclear programme. But hopes of a breakthrough have receded after the Iranian regime's crackdown on pro-reformist protesters after June's presidential elections.
British intelligence services are familiar with the secret information about Iran's experiments, sources at the Foreign and Commonwealth Office said.Reuse content | <urn:uuid:872b873b-f2d6-4366-99de-1b2f8a0e80c0> | CC-MAIN-2016-44 | http://www.standard.co.uk/news/world-iran-poised-and-able-to-build-nuclear-bomb-within-months-6788911.html | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988719453.9/warc/CC-MAIN-20161020183839-00230-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.955371 | 416 | 2.078125 | 2 |
Media groups criticised the moves as undemocratic, and the US Embassy recently raised concerns about press freedom in Sri Lanka.
Sri Lankan laws do not restrict the press from criticising leaders, but media can be charged for defamation.
The five sites blocked since Saturday were publishing reports that amount to “character assassination and violating individual privacy,” Information and Media Ministry Secretary WB Ganegala said Monday.
Many complaints were made against the sites, and the ministry collected their published reports for some time and decided to block them, he said.
The government did not describe what content it opposed, but the five sites have published material critical of the government and have raised allegations of corruption and malfeasance against politicians. No information was given on how the sites can challenge the action or if or when they will be unblocked.
The Telecommunication Regulatory Commission blocked lankaenews.com, srilankamirror.com, srilankaguardian.com, paparacigossip9.com and lankawaynews.com, commission Director General Anusha Palpita said.
A government release separately asked websites to register with the media ministry and appealed to them to adhere to media ethics and to Sri Lankan law. The requirement is new for websites, while older media formats such as newspapers, radio and television already have to register before they start publishing.
It also said some sites had published reports damaging the character of President Mahinda Rajapaksa, ministers and senior government officials.
Kelum Shivantha, the editor of srilankanmirror.com, said blocking the site was unfair as it always gave fair coverage.
“We published our reports independently and accurately. We always presented the both sides of the story,” Shivantha said. “No one has complained against us. We have not yet been informed about the reason for blocking our website.”
The government was deviating from its responsibility to strengthen democracy, said Gnanasiri Kottigoda, acting president of the Sri Lanka Working Journalist Association.
“The government is trying to block the peoples’ right to access information,” Kottigoda said. “This is not democracy, and also it’s a useless effort as the new information technology has the capability to beat those censorships.”
The government or any person affected by the websites’ content could take legal action “if they have done anything wrong. But blocking is not an acceptable solution.”
Of the five sites, lankaenews is highly critical of the government and has been blocked previously. A number of threats and attacks have been made against it in recent years.
A columnist for the website has been missing for more than a year. The website’s office was set on fire earlier this year and lankaenews blamed the government for the attack.
The US Embassy in Colombo said last week it was deeply concerned. The statement called on Sri Lankan authorities and telecommunications firms “to stop activities aimed at blocking free access in Sri Lanka to all legitimate media websites, including Lanka-e-News.”
newswarped thinks, perhaps the Chinese government could send consultants to Sri Lanka to advise them on how best to suppress free speech on the internet. | <urn:uuid:bb2ab88c-9cfe-48f8-a459-0f5df34050aa> | CC-MAIN-2016-44 | http://www.newswarped.com/2011/11/sri-lanka-government-blocks-more-news-websites/ | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988721405.66/warc/CC-MAIN-20161020183841-00313-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.969901 | 689 | 1.796875 | 2 |
The Algorithmic Imprint
When algorithmic harms emerge, a reasonable response is to stop using the algorithm to resolve concerns related to fairness, accountability, transparency, and ethics (FATE). However, just because an algorithm is removed does not imply its FATE-related issues cease to exist. In this paper, we introduce the notion of the "algorithmic imprint" to illustrate how merely removing an algorithm does not necessarily undo or mitigate its consequences. We operationalize this concept and its implications through the 2020 events surrounding the algorithmic grading of the General Certificate of Education (GCE) Advanced (A) Level exams, an internationally recognized UK-based high school diploma exam administered in over 160 countries. While the algorithmic standardization was ultimately removed due to global protests, we show how the removal failed to undo the algorithmic imprint on the sociotechnical infrastructures that shape students', teachers', and parents' lives. These events provide a rare chance to analyze the state of the world both with and without algorithmic mediation. We situate our case study in Bangladesh to illustrate how algorithms made in the Global North disproportionately impact stakeholders in the Global South. Chronicling more than a year-long community engagement consisting of 47 inter-views, we present the first coherent timeline of "what" happened in Bangladesh, contextualizing "why" and "how" they happened through the lenses of the algorithmic imprint and situated algorithmic fairness. Analyzing these events, we highlight how the contours of the algorithmic imprints can be inferred at the infrastructural, social, and individual levels. We share conceptual and practical implications around how imprint-awareness can (a) broaden the boundaries of how we think about algorithmic impact, (b) inform how we design algorithms, and (c) guide us in AI governance.
Continue reading and listening
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Subscribe to our newsletter for a weekly update on the latest podcast, news, events, and jobs postings. | <urn:uuid:fff52116-917a-4119-9d18-a423fd8f7862> | CC-MAIN-2022-33 | https://thetalkingmachines.com/article/algorithmic-imprint | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573908.30/warc/CC-MAIN-20220820043108-20220820073108-00273.warc.gz | en | 0.921868 | 407 | 2.484375 | 2 |
Please boost your Plan to download papers
The Anatomy of Human Digestive System
Pages 11 (2761 words)
Digestion is the process wherein food is mechanically and chemically breaks down into smaller pieces small enough to be utilized and absorb by the body. The human digestive system beginsfrom the mouth, passed through the esophagus, stomach, and the intestinesup to the anus for elimination. …
Digestion starts with the processing of food mechanically in the mouth. Food is crashed and grounded by teeth, the process is called mastication. This increases the surface area that makes it easier for enzymes to break it down further. Enzymes from the saliva also help to soften the food and breaks down carbohydrates molecules. Partially digested food is then transferred to the pharynx or throat. Pharynx is a common path for air and food. The two leading tubes are the esophagus that leads to the stomach and trachea or windpipe that leads to lungs. The epiglottis is a cartilage tissue that regulates the passage of either food or air. This prevents entrance of solid particles to the lungs. Food is transferred to the stomach through peristalsis. Peristalsis is a series of involuntary wave-like muscle contractions which food move along the digestive tract. The stomach serves as a mixer and grinder of the food. It is the main digestion organ that releases powerful enzymes and strong acids that further break down particulates to compounds the body can able to assimilate. Carbohydrates are converted to simple sugars, proteins are broken down into its component amino acids and lipids are degraded to monoglycerides and fatty acids. Digested food is then transferred to the small intestine that breaks down food using enzymes secreted by the liver and pancreas. ...
Not exactly what you need? | <urn:uuid:b67ee7cb-c255-4b6b-bcd6-3b6cbfa0200b> | CC-MAIN-2017-04 | https://studentshare.net/biology/47314-wiki-project-nervous-system | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280410.21/warc/CC-MAIN-20170116095120-00447-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.934384 | 375 | 3.734375 | 4 |
This posting names workplace themes most often appearing in poetry.
1. What workplace themes do you find most often appearing in poetry? Why?
As you analyze poems with workplace themes, some sample ideas include:
Themes are associated with leadership, identity, pride, responsibility, tolerance, equity (gender, racial, socioeconomic), perseverance, courage, relationships, vanity, cooperation, choices, communication, passion, desire for personal space, personality types, optimism, etc.
Since I do not know which specific poems were covered in your class, it is difficult to align with your specific thematic titles. However, these themes permeate workplace poetry as a whole. If you send another posting with specific titles and poets, it will help to identify more concrete themes.
2. Cite textual references where social justice or injustice is the theme of a poem. Is there a bias in one direction or the other? If so, why would that be?
As you explicate this question, please refer to these poets as a basis for exploration: | <urn:uuid:7ceee301-b94f-4310-9c8f-f93f79266a3e> | CC-MAIN-2017-04 | https://brainmass.com/english-language-and-literature/language/business-literature-79896 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280763.38/warc/CC-MAIN-20170116095120-00519-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.958509 | 211 | 2.9375 | 3 |
Healthy women and children through effective nutrition education and services, nutritious foods, and referrals to appropriate health and human services, delivered with integrity and respect for those we serve.
Deliver the highest quality services in the nation with integrity and respect to 100% of funded potential WIC eligible population as measured by health outcomes.
About the Program
The Special Supplemental Nutrition Program for Women, Infants and Children (WIC) is a health and nutrition program with a successful record for improving the diet of infants, children, and pregnant, postpartum, and breastfeeding women who are at risk for nutrition-related illness. The main focus of the WIC program is to educate mothers on the proper nutrition for babies and young children.
WIC promotes a better quality of life for Texas’ most vulnerable children by providing healthful foods, nutrition education for parents, immunizations for infants and young children, support for mothers who breastfeed, and medical and social-service referrals. Through referrals, WIC is able to connect participants to job programs and other educational benefits.
WIC creates significant savings in the Texas Medicaid program by promoting better nutrition among low-income pregnant women and infants. For every dollar invested in the WIC program for pregnant women, about $2.90 is saved in Medicaid expenses in Texas for women and babies in the first 60 days after birth (based on a Mathematica study, 1990).
WIC foods are a “prescription” for the nutritional needs of participants. WIC foods are rich in protein, iron, Vitamins C and A, and calcium, which are vital to healthy development during pregnancy and early childhood.
Benefits are available in all 254 Texas counties through more than 70 contracting agencies, which include city-county health departments, community action agencies, hospital districts, university medical facilities, and regional clinics of the Department of State Health Services. Texas WIC currently provides services each month to more than 900,000 women, infants, and children. WIC serves approximately 75 percent of the women and children estimated to be eligible for the program in Texas. | <urn:uuid:75438b51-35f8-4db0-840d-724b9a18a865> | CC-MAIN-2017-04 | http://www.dshs.texas.gov/wichd/gi/mission.shtm | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281353.56/warc/CC-MAIN-20170116095121-00067-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.945027 | 425 | 2.71875 | 3 |
It sounds like the GOP is going to bring back up the idea of attaching a Balanced Budget Amendment to the constitution.
In a series of tweets this morning, the National Review's star DC reporter Robert Costa basically explained that the idea is to toss a bone to the far right (by proposing a BBA) and perhaps bring Obama to the center on spending. Nobody actually thinks there's any chance of said amendment getting through Congress anytime soon.
This new move towards a BBA was anticipated a bit by George Will, who pushed for one in a column earlier this week, basically arguing that politicians are irresponsible, and only a constitutional amendment could force them to behave.
He starts by knocking over what he see as the "various" counter arguments.
The arguments against a constitutional amendment to require balanced budgets are various and, cumulatively, almost conclusive. Almost. The main arguments are:
The Constitution should be amended rarely and reluctantly. Constitutionalizing fiscal policy is a dubious undertaking. Unless carefully crafted, such an amendment might instead be a constant driver of tax increases. A carefully crafted amendment that minimizes this risk could not pass until Republicans have two-thirds majorities in both houses of Congress, which they have not had since 1871.
Furthermore, requiring a balanced budget would incite creative bookkeeping that would make a mockery of the amendment and the Constitution. For example, New York, which like 48 other states (all but Vermont) has some sort of requirement for a balanced budget, once balanced its by selling Attica Prison to itself: A state agency established to fund urban redevelopment borrowed $200 million in the bond market, gave the money to the state and took title to the prison. The state recorded as income the $200 million, declared the budget balanced, then rented the prison from the agency for a sum adequate to service the $200 million debt.
All of those points are fine, as it goes, but they're far from the complete range of arguments against the idea.
The biggest problem with a Balanced Budget Amendment is that it would destroy the economy. Yes, destroy.
The size of the deficit is mostly a function, at any given time, not of spending or taxation policies, but of economic growth.
This can easily be demonstrated by looking at a chart comparing deficits as a % of GDP vs. unemployment.
For over 60 years, throughout various policy regimes, the deficit has moved in tandem with employment. Taxation and government policy have never had much to do with how big the deficit is.
To close the deficit by law (rather than by growth) would require extreme austerity. And furthermore, that austerity would be increasingly required as the economy gets worse. So things start going downhill, the government tries to cut spending to counteract the declining tax revenues, the economy gets weaker, and soon you're on a spiral to deflationary, depressionary hell.
Cutting spending to reduce deficits doesn't work in practice. Japan has seen this play out, as its government has flirted with various austerity attempts during its log slog. Each time there's been an attempt to reduce deficits... deficits have gone up.
The top Nomura economist Richard Koo has made this point (and this chart) a centerpiece of his economic work.
So it's a terrible idea.
But that's not really what's interesting here.
What's interesting is the fact that the most basic reason to oppose this idea -- that it would demolish the economy -- isn't even well understood by the BBA's proponents, who only see minor technical reasons (there'd be loopholes!) to oppose.
It'd be fine if George Will and everyone else wanted to say that the above analysis is wrong, and that the economy would be just fine if it had to balance the budget every year. That'd be a fine to debate to have. But at least be aware that this is the main issue.
This problem isn't confined to just Will.
The same ignorance was seen when Joe Scarborough wrote about how Paul Krugman was all alone in thinking that the deficit was not an urgent issue, which was just untrue. Lots of people agree with Paul Krugman on the question.
Clearly in DC, the deficit debate is so one-sided, that many people aren't even aware there are counter-arguments or people who could be opposed, for economic reasons, the wisdom of shrinking the deficit. | <urn:uuid:dfac594d-db13-4878-aaf0-647a71081b8d> | CC-MAIN-2017-04 | http://www.businessinsider.com/george-wills-terribly-ignorant-argument-for-a-balanced-budget-amendment-2013-2 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279410.32/warc/CC-MAIN-20170116095119-00163-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.976411 | 889 | 1.84375 | 2 |
Sun shines, but chill persists
LAHORE – Dense fog and severe cold continued to disturb routine life in plains, including Lahore, on Saturday.
The prevailing weather hampered vehicular movement on inter and intra city routes besides disrupting rail and air traffic.
Experts have forecast the prevailing harsh weather conditions to persist over the next 3-4 days. Though abundance of sunshine caused increase in daytime temperature, continuously blowing winds helped maintain chill in weather.
Fog started falling in the evening and became so dense at midnight that visibility reduced to zero in open areas. Moderate to dense fog hampered vehicular movement on Motorway and National Highway. Low visibility affected flight operation besides disturbing schedule of trains. Low visibility caused cancellation of 11 domestic/international flights besides delaying arrival/departure of 33 planes. Almost all trains reached their destinations hours behind the scheduled time.
Quetta, Kalam and Kalat remained the coldest places in the country where mercury dropped 8 degree Celsius below the freezing point. Minimum temperature in Malamjabba was recorded -06C, Parachinar and Gupis -05C and Astore -04C.
Maximum and minimum temperature in Lahore was recorded 21C and 05C, respectively. Relative humidity in the evening was recorded 46 per cent.
Excessive use of gas heaters at offices and homes led to low gas pressure in urban areas, including Lahore. In certain areas women faced huge difficulties in cooking meals for families.
According to experts, continental air is prevailing over most parts of the country.
Local meteorological department has forecast cold and dry weather for most parts of the country, including Lahore, over the next 2-4 days. Foggy conditions are likely to prevail over plains in Punjab and upper Sindh during morning hours. | <urn:uuid:80479740-9eb7-4641-b359-25b7659064ad> | CC-MAIN-2022-33 | https://nation.com.pk/2017/12/17/sun-shines-but-chill-persists/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573399.40/warc/CC-MAIN-20220818185216-20220818215216-00077.warc.gz | en | 0.940447 | 363 | 2.015625 | 2 |
THE FINE ART OF MAGIC. VERY RARE, FIRST EDITION VINTAGE MAGIC BOOK. The Fine Art of Magic by George G. Edited by Jean Hugard, illustrations by Francis Rigney. One Of The Great, Classic Magic Books.
Technique for the Short Card. 4 The Short Card, The Corner Short 5 The Secret Gadget 5 Advantages of the Corner-Short Procedures 6 The Pencil Dot 8 Avoiding Contrasts 8 To Bring the Corner Short to the Top of the Pack 9 The Kaplan Fan Cut11 To bring the corner-short to the Bottom of the Pack 12 To Control a Selected Card by Means of the Corner-Short 12 The Kaplan Control of a Glimpsed Card by Means of the Corner-Short 14 Retaining Control of several Glimpsed Cards by Means of the Corner-Short 16 Controlling Three Selected Cards by Means of the Corner-Short 18 To bring a Prearranged Packet above a Chosen Card by Means of the Corner-Short 19 Obtaining a Desired Packet Instantly by Means of the Corner-Short 19 Using the Corner-Short to Retain a Prearranged Deck in Order 21. 24 Master Card Control 27 The Riffle-Force - A New Angle 29 The Gambler´s False-Cut 30 The Peek 33 The Step 35 To Glimpse or Sight a Card Secretly 37 Impromptu Marking of Cards 39. 42 Out-of-the-Room Selection 43 The X-Ray Location 44 Double-Back Corner-Short Location 46 Mind-Reading with Two Subjects 46 The "Impossible" Discovery 47 The Twenty-Sixth Card Location - Using a Corner-Short 48 Au Naturelle 51 The Topsy-Turvy Fan 55.
56 Will-o´-the-Wisp Routine 65 New Card Affinity 67 Revello Card Circle 69 The Stop! Fan Discovery 71 Fan Force 72 Kaplan´s Clock Trick 74 A Lesson in Misdirection 79 Rex Card Mystery 88 Multiple Do As I Do 90 Follow the Arrow 93 The Card in the Shoe 94 The Royal Assembly 101 The Captain Kidd Card (First Version) 103 Second Version 105 Magnetic Thought Transference 107. 110 The Lie Detector 113 Giant Trio-Flight 119 Card-Stabbing 124 The Kaplan Rising Cards 128 The Card in the Balloon 134 A Winning Wager 137 The Kaplan Torn and Restored Card 141 The Chameleon Card 145. Mind Reading Tricks with Cards.148 The Calcutta Mystery (First Version) 152 Second Version 153 Think 155 Do As I Do 158 The Princess Card Trick 163 The Yogi´s Secret 165 The New Brain-Wave Deck 167 Mahatma Thought Control 173 Psychic Sympathy 175 Twenty-One Cards A Double Prediction 179 Crystal Clairvoyance 181 Dial 182 Information, Please! 185 The Medium's Card Test 186 Yogi Spelling Test 188 The Eighteen-Cards Spelling Trick 191 The Triple Spelling Trick 193 The Three-Billet Test No. 1 194 The Three-Billet Test No. 200 The Trance Quick-and-Dead Test 204 A Capitol Problem 209 Do-As-I-Do Telephone Test 211 An Improved Sealed-Message Reading 214 Mind-Figures 218 The Spirit-Slates and Magazine Test 219 Slate Move 223 A Cigarette-Paper Pellet Switch 226 The Three-Billet Test No. 3 230 Forcing Three Numbers 231 The Odd-Even Force 233. 236 The Kaplan Coin Switch 237 The Kaplan Okito-Box Presentation 241 I Do As You Do 242 The Stack of Quarters 248 The Sympathetic Coins 251 Coin-Extraction Perfected 255. 258 The Spirit Handkerchief 260 A Billiard-Ball Transposition 263 The Brema Tube and Bill 267 The Cigarette Vanish in Handkerchief 268 The Trap-Door `Kerchief 272 Tying the Knot for the Rope Trick 275 The Game of "Thirty-One" Played with a Dice 279 The Fifteen Match-Sticks Puzzle 283. 286 Ben Ali´s Rope 292 The Lemon Trick 301 Card, Crystal Ball, and Panties 305 The Gypsy Thread Trick 313 The Comedy of Errors 319 The Kaplan Nest of Boxes Routine 329. This book is in fine condition. Marks or any writing on.
The binding is very tight. This Is A True First Edition! Binding : Hardcover Publisher : Fleming Book Company 341 Pages Incuding Illustrations. Condition can be somewhat if not very subjective.I try to be as impartial and objective as I can when stating conditon. Please look carefully at the images provided before purchasing.
I will answer all questions honestly and quickly. I appreciate all my customers and will. _gsrx_vers_795 GS 7.0.7 (795). _gsrx_vers_1151 GS 8.0.11 (1151). The item "THE FINE ART OF MAGIC 1ST EDITION & 1ST PRINTING (1948) / Very Rare Magic Book" is in sale since Monday, January 20, 2020.
This item is in the category "Collectibles\Fantasy, Mythical & Magic\Magic\Books, Lecture Notes". The seller is "magicclassics" and is located in New York, New York. This item can be shipped worldwide. | <urn:uuid:62114fea-a778-4769-8b38-661c45f142f2> | CC-MAIN-2022-33 | https://veryfineused.com/the-fine-art-of-magic-1st-edition-1st-printing-1948-very-rare-magic-book.php | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572089.53/warc/CC-MAIN-20220814234405-20220815024405-00073.warc.gz | en | 0.709122 | 1,079 | 1.570313 | 2 |
The general review of causes and mechanisms that contribute to glucocorticoid induced leukocytosis (increase
in white blood cell (WBC) counts) can be found in this EBM Consult article ... click here.1 Of the
mechanisms contributing to the increase in WBC counts, the demargination of
neutrophils (polymorphonuclear leukocytes; PMN) from the endothelial lining of
the blood vessels into the general circulation is most significant.2 In
fact, approximately 61% of the increase in WBC counts comes from this biologic
effect of glucocorticoid use and can be observed within 5-24 hours of
do glucocorticoids (e.g., dexamethasone, methylprednisolone, prednisone) effect
neutrophils (PMN) to cause this demargination?
Neutrophils reside in a number of compartments; the two compartments related to
this issue are the marginal compartment (those neutrophils attached to the
endothelium of the blood vessel) and the circulating compartment (those
circulating in the blood vessels along with other cells).5 This
distinction is important as neutrophils traveling on the endothelial surface
within the lumen of the blood vessel (i.e., in the marginal compartment) are
not reflected in a WBC count. Only the PMN freely circulating within the
circulatory compartment will be found in the venous sample used for
analysis. As such anything that causes the marginal neutrophils to detach
from the endothelial surface of the blood vessel wall will result in a greater
concentration of neutrophils in the circulatory compartment and thus increase
the WBC count. Glucocorticoids are known to do this.2-4
(both bands and segs) normally express a cell surface adhesion molecule called
L-selectin (CD26L) that is known to contribute to the formation of temporary
carbohydrate-protein bonds on the surface of the endothelial cells lining the
blood vessel wall.6,7 The selectin adhesion molecules do not interact
tightly with the protein molecules on the endothelial surfaces which explains
the neutrophil's ability to roll quickly along the surface until alerted to
transmigrate into the tissue to fight an infection.6,7 L-selectin is
known to undergo rapid turnover as the neutrophils roll along the endothelial
surface.8,9 In fact, the L-selectin are constantly being cleaved by
membrane-associated cysteine metalloproteinase (also known as sheddase).8,9
The replacement of L-selectin on the surface of the cell membrane is dependent
on the neutrophil's ability to undergo gene transcription to make more
L-selectin that is then translated, packaged and prepared for transport to the
cell surface to replace the shed L-selectin.4 If this does not occur,
then the number of temporary or loosely bound carbohydrate-protein bonds
will decrease and eventually not be sufficient to keep the neutrophil attached
to the endothelial surface and thus demargination into the circulatory
compartment will occur.4 Therefore, it is the inhibition of gene
transcription of L-selectin by glucocorticoids that results in L-selectin not
being replaced and thus reducing the ability of the neutrophil to interact with
the endothelium of the blood vessel.
do glucocorticoids decrease gene transcription of L-selectin thereby decreasing
the neutrophil's ability to replace shed L-selectin to maintain its attachment
to the endothelial surface?
exact details of how glucocorticoids turn off gene transcription for L-selectin
is not completely understood. However, glucocorticoids are very well known to
bind to glucocorticoid receptors (in particular GR-alpha) found in the
cytoplasm of the neutrophil.4 Upon binding, the glucocorticoid/GR complex
results in a conformational change that results in the dissociation of other
proteins that free the glucocorticoid/GR complex to enter into the
nucleus. After entering the nucleus it can bind to glucocorticoid
responsive elements (GRE) in the region just above the target gene (L-selectin
in this case) where it can either turn on gene transcription or inhibit
it. It is likely that this is where the inhibition occurs since mRNA
levels for L-selectin are decreased with glucocorticoid use.4 This
process does not occur immediately which explains why the progressive loss of
L-selectin starts 5-24 hours post administration of the glucocorticoid and
coincides with the rise in PMNs in the WBC count.
glucocorticoids are known to increase the concentration of neutrophils present
in the circulatory compartment thereby increasing the WBC count, the effect of
demargination is also one of the mechanisms involved in their antiinflammatory
properties. If the neutrophil is not attached to the endothelium,
transmigration into the tissue is decreased.
- Busti AJ, et al. A general review of the mechanisms for steroid or glucocorticoid (e.g., dexamethasone,
methylprednisolone, prednisone) increases the white blood cell (WBC)
count. EBM Consult.
M, Terashima T, D'yachkova Y et al. Glucocorticoid-induced
granulocytosis: contribution of marrow release and demargination of
intravascular granulocytes. Circulation 1998;98:2307-13.
Y, Gurewich Y, Gallant LA, et al. Prednisone-induced leukocytosis.
Influenced of dosage, method and duration of administration on the
degree of leukocytosis. Am J Med 1981;71:773-8.
PS, Toelboell T, Chang LC et al. Mechanisms of glucocorticoid-induced
down-regulation of neutrophil L-selectin in cattle: evidence for effects
at the gene-expression level and primarily on blood neutrophils. J
Leukoc Biol 2004;75:815-27.
- Junqueira LC, Carneiro J. Blood cells. In: Basic Histology. 11th ed. Junqueira LC, Caneiro J eds. McGraw-Hill Medical Publishing Division. New York, NY. 2005; 223-237.
- Tedder TF, Steeber DA, Chen A et al. The selectins: vascular adhesion molecules. FASEB J 1995;9:866-73.
Eeden S, Miyagashima R, Haley L et al. L-selectin expression increases
on peripheral blood polymorphonuclear leukocytes during active marrow
release. Am J Respir Crit Care Med 1995;151:500-7.
G, Murphy G, Ager A. Metalloproteinase-mediated regulation of
L-selectin levels on leucocytes. J Biol Chem 1996;271:11634-40.
JJ, Slack JL, Reddy P et al. An essential role for ectodomain shedding
in mammalian development. Science 1998;282:1281-4. | <urn:uuid:69d17d17-faa0-4309-bf4e-c633ad8180f4> | CC-MAIN-2017-04 | http://www.ebmconsult.com/articles/demargination-wbc-glucocorticoids-mechanism-selectin | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279189.36/warc/CC-MAIN-20170116095119-00053-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.847453 | 1,586 | 2.328125 | 2 |
A surge in shark attacks on Maui over the past year, including two fatal ones, hasn't stopped people from surfing and swimming in the warm ocean waters that surround the Hawaii island.
But it has spurred sales of devices that claim to keep sharks away by emitting an electric pulse.
Users strap the devices to their ankles, wetsuits or surfboards. Some are about the size of an oversized watch, others the size of a wallet. They range in price from $399 to $649. (AP)
Find more news related pictures in our photo galleries and follow us on Tumblr. | <urn:uuid:d1312e93-4469-42e1-9564-9eef6bce5dbe> | CC-MAIN-2017-04 | https://www.yahoo.com/news/photos/anti-shark-devices-popular-on-maui-slideshow/?.tsrc=viettel&ref=gs | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280825.87/warc/CC-MAIN-20170116095120-00199-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.956016 | 120 | 1.789063 | 2 |
About Winifred, Montana
Winifred is a town in north-central Fergus County, Montana, United States. The population was 156 at the 2000 census. Winifred was founded in 1913 as the terminus of a newly-built branch line of the Chicago, Milwaukee, St. Paul and Pacific Railroad ("the Milwaukee Road"). It is popularly believed to have been named after one of the railroad owner's two daughters (the other being Christina, another small town about 15 miles away). | <urn:uuid:024b500a-fd60-40cf-85e3-41dcd4463eac> | CC-MAIN-2017-04 | http://www.localrecap.com/Montana/Winifred.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560285001.96/warc/CC-MAIN-20170116095125-00310-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.976929 | 102 | 2.046875 | 2 |
We love our cats but do they love us back? With some cats, their feelings are obvious. They are affectionate, they want to be around you all the time, and you can feel their love for you. Others may be more aloof. Perhaps you just adopted an older cat and want to bond with them.
If you’ve rescued a cat from the street or an abusive situation, it may take them a while to trust you enough to be vulnerable and show love. This doesn’t mean they don’t like you. It’s a matter of self-preservation. Cats need to survive, and they do that by keeping themselves safe.
If your cat lets their guard down with you, shows you their belly, or wants to play with you, you’re doing something right. But if you’d like to strengthen your bond or just give your cat more ways to feel comfortable and secure with you, we have a few tips for you to try.
We hope that our 10 methods will bring joy to both you and your feline.
The 10 Ways to Make Your Cat Love You:
1. Be Gentle
Cats don’t like to be picked up, grabbed, or confined when they aren’t expecting it. If you try to pick your cat up from behind without warning, they could become scared or even aggressive. If you want to handle your cat, it’s always best to let them know first by approaching slowly from the front and letting them know that you’re there by petting them gently. Then, you can scoop them up without startling them.
2. Don’t Expect Too Much Too Soon
Your cat doesn’t understand life the way that you do. If you’re moving, you know that you’re packing and will be changing residences. Your cat sees chaos and boxes, and then they are being taken from their home and placed somewhere new. Many cats don’t react well to change. They can become scared and stressed. Make these changes slowly, whatever they are, and allow your cat to become comfortable at their own pace. When you arrive at the new house, give the cat their own space with familiar things to let them settle in before letting them roam the place freely. This applies to changing residences as much as it applies to changing their litter box or food. Mix old and new foods, changing completely to the new one slowly. If you get a new litter box, keep it next to the old one for a while until your cat gets comfortable with it.
3. Read Their Body Language
Cats let us know what they want and don’t want. We just have to pay attention to what they’re saying. Do you notice that your cat prefers to not be touched in a certain area? This means they’d like you to respect that and not touch them there. By softly petting your cat, you’ll see how they respond when you scratch their ears or rub their face. The positive responses, like purring and pushing into your hand, mean your cat appreciates that and would like more. However, if your cat is growling, hissing, or swatting, they would prefer not to be touched and are telling you clearly to back off.
A nice way to gain your cat’s trust is to reward them for trusting you by using treats. If you’re trying to build a relationship with your cat, show them what you like. For example, if you call your cat and they come to you, give them a treat that they love. If you’re brushing your cat, use treats to reward them for allowing it. If your cat is scared and hiding, let them know that treats will be waiting for them when they come out. Treats are the secret to getting your cat to associate you with positive feelings.
Food is not as special as treats, but it’ll work. Feeding your cat good-quality food that they like to eat lets them know that they don’t have to worry about finding their own meals and that they are cared for. They know where their food is coming from because they watch you give it to them. That’s also why they try to wake you up in the middle of the night if they’re feeling hungry. By keeping your cat well-fed, they will love you because you’re their caregiver.
6. Clean Their Bathroom
It would be great if cats could clean their own litter boxes, but since they can’t, it’s our job. Cats like to be clean and prefer their litter boxes to also be clean. To make them feel at home, keep their litter boxes scooped and refreshed daily. Emptying the entire box once a month and washing it with soap and water before refilling it with clean litter is a way to keep it smelling fresh.
Cats groom each other. You may see this if you live in a multi-cat household. It’s a way for cats to show love and acceptance. To mimic this action with your cat, brush them. Not only does it feel good, but it also removes loose hair that they would’ve either lost through shedding or swallowed while grooming themselves. It also keeps their coats healthy and shiny. Your cat will appreciate the effort and may even start to lick you as a way to groom you too! Use gentle strokes with a soft brush at first to get your cat used to the feeling. You can use a brush designed for capturing loose hair if your cat tolerates it.
8. Show Them the Love
Showing affection to your cat through petting, cuddling, and scratching lets them know that you love them. It’s a perfect way to show your cat that you’re not going to hurt them and that they are safe to return the love.
9. Don’t Punish
If your cat does something that you don’t like, punishing them is not the answer. If you strike your cat, you’ll break their trust in you and scare them unnecessarily. This is a chance to show your cat the behavior that you want to see from them instead. Teach them instead of yelling at them. Yelling will create a stressed atmosphere for your cat, and they won’t understand what you’re saying. Is your cat is scratching the furniture? Redirect them to scratch their own post. Is your cat is getting into something that they shouldn’t? Focus their attention on something else, like their favorite toys or a laser pointer. Show them what you want to see from them.
10. Mostly, Understand Them
We tend to make the mistake of thinking cats will be like dogs. Dogs are affectionate, respond to commands, and are usually predictable. Cats are solitary creatures that like to retreat to quiet places alone. We think that this means they don’t love us, but that’s not true. They just love us differently. Give them their space when they want it, and don’t expect more from them than they’re willing to give. You will strike a healthy balance of love and respect in your relationship with your cat.
We hope our tips have given you a few ideas to start strengthening the bond with your cat. They are capable of love and affection; they just show it on their own terms. Don’t be disappointed if your cat isn’t as loving as you want them to be right now. It doesn’t mean they won’t get there one day!
Featured Image Credit: Nuclear_lily, Shutterstock | <urn:uuid:805a8d42-4a62-4a42-a6a8-73b607d44e2d> | CC-MAIN-2022-33 | https://petkeen.com/tips-for-making-your-cat-love-you/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572033.91/warc/CC-MAIN-20220814113403-20220814143403-00269.warc.gz | en | 0.968126 | 1,613 | 1.859375 | 2 |
BAE Systems axes 3,000 jobs as governments slash spending
British arms manufacturer BAE Systems axed 3,000 jobs on Tuesday, mainly at its military aircraft division, as reduced spending by governments hits demand for Eurofighter Typhoon and F-35 fighter jets.
"Our customers are facing huge pressures on their defence budgets and affordability has become an increasing priority," BAE Systems chief executive Ian King said in a statement unveiling the "nearly 3,000" job losses.
"Our business needs to rise to this challenge to maintain its competitiveness and ensure its long-term future," King added.
The company has a global workforce of 100,000 people, of which 40,000 are in Britain. It has customers across more than 100 countries and enjoyed annual sales of £22.4 billion ($34.8 billion, 25.7 billion euros) in 2010.
The biggest number of job cuts will be in northern England at facilities in Brough, where 899 positions will be lost, and in Warton and Samlesbury.
There will also be jobs shed at BAE's head office in Farnborough in the south, and at other sites dotted across Britain.
The group has also begun a consultation about ending manufacturing at the Brough plant, which currently employs 1,300 workers.
The news, which sparked outrage from trade unions, followed days of intense media speculation over impending job cuts at Britain's biggest defence company.
BAE Systems said that its military aircraft wing had been hampered by a slowdown in orders for the Eurofighter Typhoon and F-35 jets.
"Some of our major programmes have seen significant changes. The four partner nations in the Typhoon programme have agreed to slow production rates to help ease their budget pressures," King said.
"Whilst this will help extend our production schedule and ensure the production line stays open until we receive anticipated export contracts, it does reduce the workload at a number of our sites."
The Eurofighter is a project involving Britain, Germany, Italy and Spain.
BAE added that it has also been hurt by painful budget cutbacks in the United States.
"Pressure on the US defence budget and top-level programme changes mean the anticipated increase in F-35 production rates will be slower than originally planned, again impacting on our expected workload," said King.
"To ensure we remain competitive, both in the UK and internationally, we need to reduce the overall costs of our businesses in line with our reduced workload."
BAE has also been hit by the British government's cuts to public spending, which include a plan to shrink its armed forces and scrap key assets like its flagship aircraft carrier.
Unite, Britain's biggest trade union, described the job losses as a "dark day" for domestic manufacturing.
"After days of speculation and rumours, our worst fears have been confirmed," said Unite official Ian Waddell.
"It's a dark day for thousands of skilled men and women across the country and it is a dark day for British manufacturing. BAE Systems have dealt a hammer blow to the UK defence industry and Unite is determined to fight the cuts."
He added: "The government cannot sit on its hands and allow these highly skilled jobs to disappear.
"We expect the Ministry of Defence to intervene urgently to protect these jobs, otherwise the UK's defence industry risks losing the critical mass it needs to maintain its reputation as a world leader in defence manufacturing."
© 2011 AFP | <urn:uuid:a467dff8-d54d-4b41-b979-cfb45582e8f8> | CC-MAIN-2017-04 | http://www.expatica.com/uk/news/BAE-Systems-axes-3000-jobs-as-governments-slash-spending_289095.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279169.4/warc/CC-MAIN-20170116095119-00218-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.966441 | 705 | 1.5 | 2 |
India is still a third-world country, with half the homes still not having plumbing and a large percentage not having electricity. But even more significant than its dynamic technology sector growing into a world-class destination for contracts and capital is the fact that India has the most intelligent electorate in the world right now.
For the first time in 30 years, India’s voters have given a decisive majority — 336 of 543 seats in the lower house of Parliament — to one party. And it is not the dynastic Congress party of Jawaharlal Nehru (and now Rahul Gandhi) that has dominated Indian politics for the 67 years since independence from Great Britain; it’s the Bharatiya Janata party (BJP) and its Prime Minister-elect, Narendra Modi.
A closer look at what Modi’s platform is and the obstacles he had to overcome will have California Republicans weeping and gnashing their teeth that they didn’t draft Modi to run for Governor of the (once) Golden State. Modi’s agenda is precisely what is needed to rescue California (if not the Untied States) from its self-inflicted disaster.
The Congress party ran on a social welfare platform, promising more goodies, more subsidies, and more government programs for the poor.
The poor rejected it. They want economic growth and expanding opportunity, and lots of it. A 5% growth rate, which would be considered miraculous if it could be achieved anywhere in the West, is not good enough; they want 8% or better. They’ve tasted that in the last decade, and they want more of it. Modi and the BJP declined to play Santa Claus; refrained from stirring the identity politics of religion, region, caste, and ethnicity; restrained their more strident Hindu nationalist wing and tendencies; and instead focused on economic principles and basic good governance. The voters rewarded them for these principles and for their courage in proclaiming and defending them.
American Republicans might learn a thing or two about how an effective modern campaign is run, as the BJP left the Congress party in the dark ages with savvy use of technology and social media. Just because people don’t have electricity in their homes doesn’t mean they don’t have iPhones, Facebook, and Twitter. Modi even appeared as a holograph at events where he was unable to be physically present.
Manmohan Singh, prime minister of India for the past 10 years, Finance Minister from 1991-96, and Leader of the opposition party from 1998-2004, has been a potent pro-free market voice and force in India’s rise over the past 20 years to the status of international technology powerhouse. But his party, as too often happens with parties that get too cozy with unchallenged power for too long, has been rocked with corruption scandals in recent years. Apparatchiks have been feathering their own nests while the roads and bridges crumble (sound familiar?) The voters have had enough and want a party that can credibly promise a cleaner and more accountable regime–and modern highways and ports too.
Someone wake me when California voters demand the same.
The views expressed in this opinion article are solely those of their author and are not necessarily either shared or endorsed by WesternJournalism.com.
This post originally appeared on Western Journalism – Informing And Equipping Americans Who Love Freedom | <urn:uuid:48fb6871-cf7e-44a1-aa67-38de26d90c98> | CC-MAIN-2016-44 | http://www.exposeobama.com/2014/05/19/india-gets-it-but-america-doesnt/ | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988721027.15/warc/CC-MAIN-20161020183841-00550-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.96327 | 690 | 2.15625 | 2 |
New Drug Target Identified for Treatment of Type 2 Diabetes
June 9, 2012
A mitochondrial protein complex has been identified by researchers at Metabolic Solutions Development Company (MSDC) through which anti-diabetic drugs exert their insulin sensitizing effects when used to treat patients diagnosed with type 2 diabetes. The mitochondrial protein complex is being referred to as the mitochondrial Target of Thiazolidinediones (TZDs), or mTOT™.
The mTOT complex functions as a molecular “sensor switch” connecting mitochondrial metabolism to important cellular activities, such as carbohydrate, lipid, and amino acid metabolism, that are out of balance in patients with type 2 diabetes. Such imbalances may also play a role in other diseases of aging such as Alzheimer’s disease and Parkinson’s disease, as well certain genetic diseases such as polycystic kidney disease.
Using a novel drug analog photo-catalyzable affinity probe and mass spectrometry-based proteomics, MSDC scientists identified two phylogenetically-conserved proteins in the inner mitochondrial membrane, meaning these proteins are present in, and play an important role in the development of, organisms from yeast and fruit flies to humans. Proof of identity has been demonstrated by gene expression and knockdown of expression.
The discovery by MSDC researchers suggests the lowering of plasma glucose can be achieved without having to activate a nuclear receptor called PPARg. Previously, it was believed that both the activity and the side-effects of the only approved class of drugs used to treat insulin resistance — the core problem for persons diagnosed with type 2 diabetes — were mediated through PPARg. However, it is now generally accepted that over-activation of PPARg drives the unwanted and often unacceptable side effects associated with the currently approved anti-diabetic insulin sensitizers, which are PPARg agonists.
Data from recently completed Phase 2 clinical studies of MSDC-0160, as well as studies in obese mice and Phase 2 clinical studies in diabetic patients of a second compound, MSDC-0602, support the company’s hypothesis that the insulin sensitizing pharmacology of these first in class mTOT Modulators™ can occur independent of the activation of PPARg.
Two papers published online by two separate groups in the May 24, 2012 Science Express (and subsequently in the July 6, 2012 edition of Science, http://www.sciencemag.org/content/337/6090/93.abstract and http://www.sciencemag.org/content/337/6090/96.abstract) have coincidentally found that two proteins in the mTOT complex, which they renamed Mpc1 and Mpc2, are part of a pyruvate carrier mechanism. Together these findings place the mTOT recognition complex at the “crossroads of metabolism” and provide a new way to look at insulin sensitizers. | <urn:uuid:9ffe2cc8-00f2-4d72-8e3f-b8e14b19d49b> | CC-MAIN-2017-04 | http://www.msdrx.com/new-drug-target-identified-for-treatment-of-type-2-diabetes | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281424.85/warc/CC-MAIN-20170116095121-00338-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.942977 | 597 | 2.1875 | 2 |
Create mental space through meditation.
Ever been curious about the benefits of meditation to ease stress and anxiety? Is shivasana your favorite part of a yoga class, because you finally get to be still and relax? Deepak Chopra says, “Meditation is not a way of making your mind quiet. It’s a way of entering into the quiet that’s already there – buried under the 50,000 thoughts the average person thinks every day.”
Come join a 30-minute meditation session — appropriate for beginners and experienced practitioners — that will introduce meditation techniques based on the vipassana, or insight, tradition, and the practice of mindfulness.
Scientific studies have shown that meditation can increase concentration, help manage difficult emotions, improve a sense of calm and well-being, and decrease stress and anxiety. Our guided meditation will take participants through a process of relaxation, body scans, single-pointed breath focus to be grounded in the moment-to-moment experience.
This class is led by Laura Trejo, a 500-hour Yoga Alliance registered teacher trained in vinyasa yoga, a NASM-certified personal trainer, a mat pilates teacher, a black belt in tae kwon do, and a reiki practitioner who trained at the Center for Integrative Medicine.
“If you can go to the gym to strengthen your body, why not meditate to strengthen your mindfulness muscle? I guide the class in mindfulness meditation after having meditation practitioners do a progressive relaxation exercise. I ask students to focus on their breath as a tool of the meditation. However, the actual meditation practice happens when a practitioner notices, without judgment, that they have become distracted by their thoughts and they can return the focus to the breath whenever they are ready.
Taking time to meditate allows you to disengage from your computers, TV, and smartphones and notice what you are thinking and feeling. Each time you meditate you can strengthen your mindfulness muscle which you can then incorporate into your daily life. Rather than reacting mindlessly to challenging situations and people you can respond more wisely as you notice what thoughts, emotions, and physical sensations arise for you. You can’t control what curveballs life throws at you, but you can choose how you respond.” – Laura Trejo
Unlimited meditation classes are included with MINT class-access memberships. You may also attend via our a la carte program. Blankets and chairs will be provided, but feel free to bring cushions or pillows to support your sitting posture. | <urn:uuid:51a37e9a-b17a-4bcb-bcd8-4bef3676be8b> | CC-MAIN-2022-33 | https://www.mintdc.com/gym-class-packages/meditation/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570868.47/warc/CC-MAIN-20220808152744-20220808182744-00074.warc.gz | en | 0.928858 | 523 | 1.789063 | 2 |
Proceedings of The International Academic Conference on Teaching, Learning, and Education
School Management in Preparation of Pre-service Science Teachers
Zuzana Haláková, Soňa Nagyová and Tibor Nagy
The domain of school management represents an important part in pre-service teachers´ vocational preparation and inexperienced teachers´ advancement. The question is what kind and depth of knowledge should they have at command before entering the school building, or the classroom. In the contribution, there are several proposals how university students can acquaint themselves with different areas of school management interest. The purpose is to describe and to analyse approaches to the teaching it in Slovak conditions. The eight year´s lasted experience is presented and during this period 446 pre-service science teachers went through the content in semestral study. We were analysing their effort, their products created during lessons, or assignments prepared for the lessons. Several of the problems were solved in small groups (usually of three members), some of them were handed in individually, always precisely elaborated and evaluated. There were used the elements of basic analysis and the skilled observation of the students´ group or individual work. Many of the topics presented were considered positively remembering that they are connected and could be probably helpful for practice. A great advantage was, that when students had passed the school management course, they were going to sit in on class for their first professional experience and could discuss and elaborate many different problems live in school environment.
Keywords: comparative pedagogy, pre-service science teacher, school management. | <urn:uuid:8bc33a7f-056c-40c9-bdaf-9f61b44fd420> | CC-MAIN-2022-33 | https://www.dpublication.com/abstract-of-tle/tle-536/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571097.39/warc/CC-MAIN-20220810010059-20220810040059-00273.warc.gz | en | 0.97569 | 326 | 2.421875 | 2 |
We face strong headwinds from those who seek to undermine liberal democracies, as well as those who are apathetic or don’t know any better.
It’s hard to overstate the importance of flu shots in the fight against the novel coronavirus.
The reassuring voice of business will be critical before and after Election Day.
Millions of children are stuck at home because of the coronavirus pandemic, relying on their parents to function as part-time teachers in support of virtual classroom instruction.
The second episode of Path Forward explores the importance of COVID-19 testing to the short-term recovery of the United States. U.S. Chamber of Commerce President Suzanne Clark was joined by experts who shared their perspect
On November 7, 2019, Monticello’s Thomas Jefferson joined the Chamber Foundation for a forum to discuss the state of civic knowledge, civic engagement, and civil discourse in America. This is an excerpt from his remarks to the audience. | <urn:uuid:a657584e-7ebd-4b4a-8e30-35b91a880c3e> | CC-MAIN-2022-33 | https://www.uschamberfoundation.org/blog?topics%5B5%5D=2024&topics%5B6%5D=2152&topics%5B8%5D=2167&topics%5B9%5D=1709&topics%5B10%5D=1778&topics%5B11%5D=1558&topics%5B13%5D=1714&%3Btopics%5B1%5D=1710¢er%5B0%5D=5¢er%5B1%5D=2140 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573029.81/warc/CC-MAIN-20220817153027-20220817183027-00274.warc.gz | en | 0.957104 | 202 | 1.546875 | 2 |
- freely available
Nutrients 2014, 6(1), 261-275; doi:10.3390/nu6010261
Abstract: The use of human milk fortifiers (HMF) helps to meet the high nutritional requirements of the human milk-fed premature infant. Previously available powdered products have not met the protein requirements of the preterm infant population and many neonatologists add powder protein modulars to help meet protein needs. The use of powdered products is discouraged in neonatal intensive care units (NICU) due to concern for invasive infection. The use of a commercially available acidified liquid product with higher protein content was implemented to address these two concerns. During the course of this implementation, poor growth and clinically significant acidosis of infants on Acidified Liquid HMF (ALHMF) was observed. The purpose of this study was to quantify those observations by comparing infant outcomes between groups receiving the ALHMF vs. infants receiving powdered HMF (PHMF). A retrospective chart review compared outcomes of human milk-fed premature infants <2000 g receiving the ALHMF (n = 23) and the PHMF (n = 46). Infant growth, enteral feeding tolerance and provision, and incidence of necrotizing enterocolitis (NEC), metabolic acidosis, and diaper dermatitis were compared between the two groups. No infants were excluded from this study based on acuity. Use of ALHMF resulted in a higher incidence of metabolic acidosis (p = 0.002). Growth while on HMF as measured in both g/kg/day (10.59 vs. 15.37, p < 0.0001) and in g/day (23.66 vs. 31.27, p = 0.0001) was slower in the ALHMF group, on increased mean cal/kg/day (128.7 vs. 117.3, p = 0.13) with nearly twice as many infants on the ALHMF requiring increased fortification of enteral feedings beyond 24 cal/ounce to promote adequate growth (48% vs. 26%, p = 0.10). Although we were not powered to study NEC as a primary outcome, NEC was significantly increased in the ALHMF group. (13% vs. 0%, p = 0.03). Use of a LHMF in an unrestricted NICU population resulted in an increase in clinical complications within a high-acuity NICU, including metabolic acidosis and poor growth. Although further research is needed to assess outcomes among infants with a variety of clinical acuities, gestational ages, and weights to confirm these findings, based on this experience, caution is urged to avoid potential risks.
Infants born prematurely have increased nutrient needs compared to those born at term [1,2,3]. Nutrition-related goals for premature infants aim to mimic fetal nutrient accretion and growth in utero , yet many develop extrauterine growth restriction (EUGR) .
Despite the availability of customized, nutrient-dense enteral formulas, the American Academy of Pediatrics strongly supports the use of human milk for premature infants . However, unfortified human milk remains inadequate to meet the high nutrient requirements of premature infants [1,4,7]. Provision of unfortified human milk has subsequently been linked to suboptimal growth (development of EUGR or growth < 15 g/kg/day), reduced bone density leading to osteopenia of prematurity and a clinical diagnosis of rickets, and the secondary consequences of each [1,4].
The use of commercial human milk fortifiers (HMF) allows for a more optimal provision of essential nutrients to meet premature infant requirements [1,4,7]. Macronutrient recommendations for low birth weight premature infants vary, but consensus goal ranges suggest enteral intake of 110–120 cal/kg/day and 3.4–4.4 g protein/kg/day . Protein is specifically emphasized, as early and higher provisions promote more desirable growth and clinical outcomes [8,9]. The use of HMF has been shown to be both safe and effective in improving growth and nutrition status of premature infants compared to unfortified human milk [7,10,11]. In recent years the use of HMF with additional powdered protein modular has been presented as a method of supplying the preterm infant with the recommended amount of enteral protein to provide improved linear growth and neurodevelopmental outcomes [12,13].
Human milk fortifiers have primarily been available in powder form, although the United States Food and Drug Administration discourages the use of powdered forms in the neonatal intensive care units (NICU) secondary to contamination risk . They additionally advise that “alternatives to powdered forms should be chosen when possible” . To comply with this recommendation and achieve improved protein intake, The Nebraska Medical Center (TNMC) NICU changed standard human milk fortification practices with a powdered product when an acidified liquid HMF (ALHMF) with improved protein delivery became available. However, in the four months following our initial use of the ALHMF, clinical observations of infants receiving the ALHMF suggested an increased feeding intolerance, increased incidence of metabolic acidosis, poor growth, and a need for higher caloric densities of enteral feedings to promote adequate growth. Due to our concern for patient outcomes, use of the ALHMF was discontinued. The purpose of this study is to objectively quantify these clinical observations by comparing outcomes of infants receiving the ALHMF to those receiving the originally-used PHMF. Our study also looked to identify potential risk factors for the development of the observed clinical complications, as previous research evaluating the ALHMF also documented changes in pH and CO2 when compared to a powder HMF (PHMF) .
2. Patients and Methods
2.1. Participants and Study Design
The institutional review board at the University of Nebraska Medical Center (Omaha, NE, USA) approved this study. Data was retrospectively collected from inpatient electronic medical records of all infants admitted to the NICU, between October 2009 and July 2011, if they met the following inclusion criteria: birth weight (BW) < 2000 g, received enteral feedings as fortified maternal breast milk during NICU stay, and remained in the NICU ≥ 14 days. Exclusion criteria included infants with congenital abnormalities or conditions that significantly inhibited growth, such as Trisomy 13. No infants were excluded based on clinical acuity. After extensive chart review, 69 infants were eligible for the study.
2.2. Comparison and Use of Human Milk Fortifiers
Maternal breast milk (MBM) was fortified according to manufacturer directions. Ingredient and estimated nutrient compositions of fortified preterm human milk were obtained from online nutritional references [16,17]. Table 1 provides a composition comparison for key nutrients and ingredients.
|24-Calorie-Per-Ounce Fortified Premature Human Milk [16,17]|
|Per 100 mL||Powder HMF||Liquid HMF|
|Vitamin D (IU)||119||200|
|Primary Fortifier Macronutrient Ingredients||nonfat milk, whey protein concentrate, corn syrup solids, medium-chain triglycerides (MCT oil)||water, whey protein isolate hydrolysate (milk), medium chain triglycerides (MCT oil), vegetable oil (soy and high oleic sunflower oils)|
-: Information not avaliable.
Enteral feedings are initiated in this NICU within the first one to three days of life with Human Milk (MBM as available or donor milk form the Milk Bank of Austin) at 20 mL/kg/day, trophic feedings are continued for three to five days at the discretion of the attending neonatologist, and then feedings are advanced daily by 20 mL/kg/day with human milk fortification beginning at 80–100 mL/kg/day enteral volume. A protein modular is utilized to improve protein intake to approximately 4 g/kg/day enteral protein once caloric density is 24 kcal/oz. While using the ALHMF, no additional protein modular was utilized. There were no other nutrition differences during the two time periods. Nutrition is managed closely per unit protocol and is very consistent from provider to provider.
According to unit policy, infants receiving the PHMF also received supplementation with a protein modular to provide approximately 4 g protein/kg/day when fed at goal volumes.
Sole use of the ALHMF was initiated on April 1, 2011. Infants receiving the PHMF before this date of fortification change were included in the control group (PHMF, n = 46). Infants receiving the ALHMF following this date were included in the study group (ALHMF, n = 23). Infants transitioned from the PHMF to the LHMF on the date of fortification change were excluded.
2.3. Data Collection
Four investigators familiar with the electronic medical record and NICU terminology obtained all data in a consistent predetermined manner. Collected information was reviewed for accuracy and corrected if an electronic error occurred. All available information on each infant was included in the analysis and is displayed in the tables.
Demographic information was collected for all infants including gender, gestational age at birth and discharge, and day of life (DOL) at discharge. Additional clinical outcomes were collected including the presence of bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), diaper dermatitis, and death. Treatment requirements were coded similarly if an infant required: oxygen at 36 weeks estimated gestational age (EGA), ROP procedure, IVH shunt, Avastin treatment, Dexamethasone use, and Bicitra use. ROP stage, IVH grade, and number of days of Dexamethasone use were included if available.
Infants were weighed daily on a gram scale, and head circumference and length (centimeters) were recorded weekly by nursing staff using a measuring tape. Fenton growth curve percentile rankings [18,19] were electronically plotted for each recorded anthropometric measurement. Weight, head circumference, and length measurements with associated Fenton percentile rankings were taken for infants at birth and at 36 weeks EGA, if available.
Enteral feeding data collected included day of life (DOL) enteral feedings were initiated, DOL full enteral feedings were reached (with a discontinuation of parenteral nutrition support), and the number of times enteral feedings were held (not secondary to preparation for a procedure). Maximum caloric density and number of days on enteral feedings >24 cal/ounce were collected for infants requiring caloric densities higher than the standard 24 cal/ounce to promote adequate growth.
Daily average provision of calories and protein (g) per kg body weight were calculated for infants in each group if they received ≥50% of enteral feedings as fortified MBM during NICU stay. These averages were taken when fortified enteral feedings reached a minimum of 140 mL/kg/day until either daily intake was consistently less than this amount, the infant was changed to unfortified MBM, or the infant received greater than 50% infant formula. Growth and nutrition was evaluated for the groups comparing only growth during the period where the infant received ≥50% of enteral feedings as fortified MBM. An electronic medical system (Intuacare®: Omaha, NE, USA) contained protein references for breast milk and specified enteral formulas and caloric density. Nursing staff documented daily intake of breast milk or specified enteral formulas, thus, daily calorie and protein provision per kg of body weight were electronically calculated using the daily-recorded weight. The electronic medical system also calculated the percentages of MBM vs. infant formula received according to nursing documentation.
2.7. Laboratory Measurements
Maximum creatinine, maximum blood urea nitrogen (BUN) level, maximum base deficit value, maximum calcium level, and lowest carbon dioxide (CO2) lab values were collected, if available, after DOL 14 and DOL 30 for all infants. Values were not collected before DOL 14 to eliminate those reflective of parenteral nutrition support and unfortified enteral feedings. Phosphorus and pH were not consistently nor routinely obtained in this patient population and were therefore not collected in this retrospective study.
2.8. Data Analysis
Descriptive statistics were displayed for all variables by type of milk (powder vs. liquid) given. The Wilcoxon rank sum test was used to compare continuous data between the milks groups. Associations of categorical variables were assessed with the Fisher’s exact test. A p-value ≤ 0.05 was considered statistically significant. To assess the difference in growth patterns between infants given powder and infants given liquid, a mixed effects model was used. We included random slopes and intercepts for each subject to capture individual growth pattern as well as fixed effects for group and day and a group day interaction term. A significant interaction of day and group indicates differing growth patterns based on group. Growth Velocity (GV) was calculated using Equation 1 .
There were 46 infants in the PHMF group (21 males, 25 females) and 23 infants in the ALHMF group (13 males, 10 females) (p = 0.45). Additional baseline characteristics were not statistically significant between the two groups, as shown in Table 2. Enteral feeding data, growth and analyzed lab values are displayed in Table 3. Clinical outcomes are displayed in Table 4. ROP stage, IVH grade, and number of days of Dexamethasone use were not statistically significant and are not included in Table 4.
|n||Mean||SD (±)||n||Mean||SD (±)|
|CGA at Birth||46||29.5||3.0||23||30.3||2.5||0.21|
|Birth Weight (g)||46||1293.7||407.5||23||1437.3||375.6||0.13|
|Birth Weight Percentile||46||31.4||24.7||23||36||26.5||0.82|
|Weight at 36 Weeks CGA (g) #||44||2245.9||450.72||18||2071.2||367.4||0.17|
|Weight Percentile at 36 Weeks CGA #||44||18.6||24.4||18||10.3||13.8||0.22|
|HC at Birth (cm)||46||27.2||3.4||22||27.9||2.1||0.19|
|HC Percentile at Birth||46||29.9||23.1||22||33.6||26.3||0.7|
|HC at 36 Weeks CGA (cm) #||42||32.5||2.6||19||31.9||1.5||0.37|
|HC Percentile at 36 Weeks CGA #||42||38.8||30.7||19||31.4||24.6||0.5|
|Length at Birth (cm)||46||38.6||3.9||21||40.4||2.8||0.07|
|Length Percentile at Birth||46||31.4||24.6||22||32.8||21.9||0.68|
|Length at 36 Weeks CGA (cm) #||42||44.2||3.3||19||43.5||4.6||0.44|
|Length Percentile at 36 Weeks CGA #||42||17.3||22.3||19||21.3||28.1||0.93|
# Growth at these time points represents nutrition delivery throughout hospitalization not just breast milk with PHMF and ALHMF.
|Average Daily Provision of Protein per kg Weight||42||3.9||18||4.3||0.0014|
|CO2 Minimum after DOL 14||33||23||16||18.5||0.002|
|CO2 Minimum after DOL 30||23||25||8||20||0.002|
|Growth Velocity (g/kg/day) while on HMF||46||15.37||21||10.59||<0.0001|
|Growth (g/day, while on HMF)||46||31.27||21||23.66||0.0001|
|DOL Enteral Feedings Started||46||3.0||22||1.1||0.12|
|BUN Maximum after DOL 14||33||18||16||20||0.28|
|BUN Maximum after DOL 30||23||18||8||16||0.91|
|n (%)||n (%)|
|NEC||0 (0%)||3 (13%)||0.03|
|ROP||16 (35%)||3 (13%)||0.09|
|ROP Procedure||3 (7%)||2 (9%)||1.00|
|IVH (any)||18 (39%)||4 (17%)||0.10|
|Dexamethasone Treatment||9 (20%)||1 (5%)||0.15|
|Bicitra Treatment||0 (0%)||1 (5%)||0.31|
|Death||0 (0%)||1 (4%)||0.33|
|Diaper Dermatitis||5 (11%)||4 (18%)||0.46|
|BPD||9 (20%)||3 (14%)||0.74|
3.1. Safety and Clinical Outcomes
Mean lowest CO2 lab values (collected while infants were enterally feeding and not acutely ill) were significantly lower in the ALHMF group compared to the PHMF group after both DOL 14 (18.5 vs. 23 mmol/L, p = 0.002) and DOL 30 (20 vs. 25 mmol/L, p = 0.002). Lowest CO2 lab values after DOL 14 are displayed comparatively in Figure 1. Lowest values after DOL 30 are displayed similarly in Figure 2. Maximum BUN and creatinine levels were similar between the two fortifier groups and were not statistically significant. All other analyzed lab values were not statistically different. All laboratory data in this retrospective study was obtained for clinical purposes regardless of the fortifier group.
Incidence of NEC (a variable we were not powered to evaluate) was significantly higher in the ALHMF group compared to the PHMF group (13% vs. 0%, p = 0.03).
3.2. Enteral Nutrition and Growth
Growth was significantly different between the two groups as measured in g/kg/day and is described in Figure 3. Infant growth as measured in g/day from birth to 36 weeks EGA was 23.7 in the PHMF group and 18.8 in the LHMF group (p = 0.057). There were no statistically significant differences in the length of time to full feedings or the number of times that feedings were held that could account for the difference in growth rates between the two groups.
Daily average protein/kg/day provision was higher in the ALHMF group compared to the PHMF group (4.3 vs. 3.9 g, p = 0.0014). Mean enteral calorie provisions in the ALHMF group were higher than in the PHMF group, 117.3 kcal/kg/day in the PHMF group as compared to 128.7 kcal/kg/day for infants in the ALHMF group (p = 0.057). A higher proportion of infants in the ALHMF group required increased caloric density of feedings >24 cal/ounce as compared to infants in the PHMF group, (48% vs. 26%, p = 0.10). While this did not reach a statistical difference, clinically this was notable.
To our knowledge, we are the first study to date to report our clinical findings of increased complications with the use of ALHMF in a Level IIIc clinical setting. In our retrospective analysis of acidosis, growth, and clinical outcomes in NICU infants fed with human milk fortified with LHMF and PHMF we found significant acidosis and poor growth in the infants receiving LHMF. These findings were very consistent with our clinical impressions during our clinical use of the LHMF. We were also surprised to see increased NEC in the ALHMF group. Although we were not powered as a primary outcome to evaluate NEC, we strongly encourage cautious further evaluation of the product in the clinical setting with regards to this serious outcome.
A key difference in the ALHMF as compared to the PHMF is the acidification process required for sterilization. This difference is likely to explain the increased complications seen in the ALHMF group. The preterm infant’s inability to buffer this acid load likely led to an increase in clinical complications including acidosis, poor growth, and, possibly, NEC.
There was a higher incidence of clinically significant metabolic acidosis in the ALHMF group, with one infant requiring treatment with Bicitra. No infants in the PHMF group required Bicitra treatment, even with twice as many patients in this group. Premature infants are susceptible to metabolic acidosis and renal tubular acidosis. However, these imbalances of acid base status should begin to normalize after the first weeks of extrauterine life . Considering similar baseline characteristics, we hypothesize additional enteral acid load was a potential contributor to this increased incidence of metabolic acidosis in the LHMF group.
Premature infants are at risk for developing metabolic acidosis secondary to immature metabolic processes, a lower renal capacity to adequately excrete acid, and higher urinary losses of bicarbonate [2,4,22]. Quantity of protein may affect metabolic processes; however the median daily average protein provisions for each fortifier group were within the currently recommended ranges . No clearly defined amount for maximum protein provision exists, however, it is suggested that intakes greater than 6 g/kg/day are poorly tolerated . Maximum daily average protein provisions for both groups were below this level. Another reference states that protein provisions greater than 5 g/kg/day may cause azotemia , but each group had intakes below this value, and maximum BUN and creatinine levels were not different in the two fortifier groups. Having increased protein intake in the PHMF group as well as the ALHMF group helps to illuminate that increased protein content in the ALHMF was not likely the cause of the adverse outcomes.
We question if the acidification sterilization process of the ALHMF may contribute to this acidosis in some fragile premature infants. Our patient population included in this study was not limited by respiratory acuity, as was the population in the Moya et al. paper . We hypothesize that our more inclusive population of both healthy infants and more fragile infants who may have less respiratory stability decreases their capability to buffer the acid load provided in the ALHMF resulting in clinical acidosis in some cases requiring medical therapy. It may be unwise in a fragile preterm infant population to minimize the clinical significance of the metabolic acidosis noted in the ALHMF groups in our study, the study conducted by Moya et al. , who reported that infants fed the ALHMF had significantly lower pH (at day six), bicarbonate (at day six and 14), and CO2 (at day 14 and 28), and significantly higher chloride (at day 14 and 28). Additionally, in an abstract evaluating 100 infants, 50 fed with ALHMF and 50 fed with PHMF, published by Cibulskis et al., from Saint Louis University at the 2013 AAP_NCE, similar metabolic acidosis is described in this patient population (54% ALHMF vs. 10% PHMF, p = 0.0001) . As reported in their abstract, this grouptreated the acidosis as if it were clinically significant, discontinuing ALHMF on 21/50 patients due to a clinical diagnosis of acidosis .
4.2. Enteral Nutrition and Growth
Infants in the PHMF group received a mean daily calorie intake of 117.3 kcal/kg/day as compared to infants in the ALHMF group who received a mean calorie intake of 128.7 kcal/kg/day. Infants in the ALHMF group also received a median of 0.4 g protein/kg/day more than the infants in the PHMF group. Despite higher protein and calorie provisions in the LHMF group, growth during the HMF period was slower between the two groups as evaluated by several methods: in a mixed effects model evaluated in g/kg/day (p = 0.002), in g/day (p = 0.0001), and by growth velocity in g/kg/day (p < 0.0001). Noted also, is that ALHMF infants experienced an additional decrease of 10 growth curve percentiles for weight from birth to 36 weeks EGA when compared to infants in the PHMF group (growth at 36 weeks is representative of nutrition delivery that is not limited to the period evaluated on PHMF and ALHMF). As Dexamethasone use inhibits growth in premature infants , we further note that fewer infants in the ALHMF group (5%) compared to the PHMF group (20%) required this drug for clinical treatment (p = 0.15).
Maintaining appropriate growth in this patient population was a high priority, so infants with suboptimal growth were fed increased caloric density feedings above 24 cal/oz. Though not statistically significant, a higher proportion of infants in the ALHMF group (48%) required caloric densities greater than 24 cal/ounce when compared to the PHMF group (26%). Had those 48% of infants in the ALHMF group not been prescribed increased caloric densities due to clinical observations of poor growth differences in growth throughout the hospitalization would likely have been larger between the PHMF groups and ALHMF groups. The statistical significance in infant growth as noted in g/kg/day is seen in spite of the high priority our unit takes in maintaining optimal growth and the subsequent aggressive adjustment of caloric density to achieve desired results. This was ultimately the reason 26% of infants receiving ALHMF were transitioned to receive the PHMF once the ALHMF use was discontinued in the NICU.
Not only are these growth effects consistent with the findings of Moya et al., they raise further questions . Moya et al., reported no significant differences in rate of weight gain or head circumference growth between infants fed this same ALHMF and infants fed a PHMF, even though the human milk fortified with ALHMF contained 23% more protein (3.2 vs. 2.6 g protein/100 mL fortified preterm human milk) . In our study, even though we compensated for the difference in protein content so that protein intake was similar, there was still poorer growth in infants fed ALHMF.
At least part of the inability of the additional protein to improve growth may be due to the acidosis noted above. It is well-known that infants with metabolic acidosis hyperventilate, as the expiration of CO2 drives the elimination of H+ ions through the bicarbonate buffering system. What is less well recognized is that protein catabolism can also be utilized to decrease acidity by the elimination of H+ ions through the urinary excretion of NH4+. Acidosis reduces protein synthesis in rats and leads to protein catabolism in humans .
No infants in PHMF group developed NEC compared to 13% in the ALHMF group. Reasons for these occurrences remain unclear, as similar prevention strategies were followed for each group. Previous implementation of aggressive nutrition practices in our unit demonstrated improved feeding tolerance and clinical outcomes, with no increased incidence of NEC . These nutrition practices remained unchanged during the study period, and no additional clinical practices were implemented concurrent with the change in human milk fortification. Slow rate of enteral feeding advancement remained consistent between both groups, as evidenced by no statistically significant differences in length to full enteral feedings. No changes in brand or caloric density of premature infant formula were made, and infant formula was utilized equally in both groups if no MBM was available. As no additional practice changes were implemented during this study period, we can neither confirm nor exclude use of the ALHMF as a contributor to these occurrences of NEC. Although this study was not powered to detect NEC based on historical incidence in our unit with rates over the last five years ranging from 2% to 5% from our Vermont Oxford Network data, one should consider that significant differences with small sample sizes may either reflect coincidental effects due to sample size, or may be due to a real difference that is unexpectedly large.
4.4. Metabolic Acidosis
Literature suggests that premature infant formulas contain a high renal acid load, though human milk contains less [2,21]. Research has additionally demonstrated that the composition of infant formulas may affect the urinary pH and nutrient excretion of premature infants [21,22]. It is further proposed that high renal acid loads contribute to maximum renal acid stimulation (urine pH < 5.4) in premature infants with immature renal function. Previous research studies have demonstrated that infants with metabolic acidosis or maximum renal acid stimulation exhibit decreased growth [28,29]. This may also result in an increase in urinary sodium excretion [24,29] and a decrease in nitrogen assimilation . Blood sampling for acid-base indicators may not be significantly abnormal in the presence of maximum renal acid excretion [22,28]. However, CO2 values may trend low , which was clearly observed among infants in the ALHMF group (p = 0.002).
Our results showing increased acidosis in the ALHMF group raise further concerns with use of the ALHMF, as infants with metabolic acidosis may experience altered nutrient metabolism [28,31] and decreased bone mineralization , leading to poor growth and osteopenia of prematurity.
Poor growth in the ALHMF group may also be attributed to changes to the nutrient content of the milk caused by acidification as described by Erickson et al. . This group reported significant changes in acidified breast milk, including decreased total protein content, lipase activity, and free fatty acids . The nutritional changes in the composition of acidified breast milk documented by Erickson in vitro may have led to the in vivo growth deficiencies noted in our ALHMF population .
5. Strengths and Limitations
This study is the first to quantify results of use of ALHMF in a Level IIIc NICU setting. We are uniquely situated to evaluate outcomes of our use of ALHMF in our patient population for several important reasons. First, we initiated utilization of this product on all infants at one time. There was no possibility of crossover product use to decrease the validity of the data. Additionally, we used this product on all infants who would be eligible to receive fortified human milk, as would be expected in a clinical NICU practice. This makes our data very relevant and applicable to clinical NICU settings.
Second, our clinical management of nutrition in this patient population has been published and remains very successful with excellent growth and low baseline rates of NEC. Not only do we manage nutrition care of this population very closely, but we also have a defined protocol in place so that infants (except for fortification method) receive the same nutrition interventions over time regardless of which group, PHMF or ALHMF, they received.
Additionally, our nutrition management with additional protein added to the PHMF group makes the comparison of the two groups more relevant by giving them a more similar nutrient intake at baseline than a comparison of ALHMF and PHMF alone which compares a large difference in delivered protein.
Finally, we have a very detailed nutrition documentation medical record system, Intuacare. This system allows for easy retrieval of detailed nutrition information including daily percentages of breast milk, daily caloric intake, and daily protein intake in g/kg/day. This allows for minimal reporting error in a retrospective study, such as this, and provides an excellent historical representation of each infant’s delivered nutrition.
This retrospective review of a clinical trial of a commercially available acidified liquid human milk fortifier has several limitations including the retrospective nature of the study, and a modest sample size, which limits the power of some data points. These limitations were partially reduced by our reliance on electronic documentation for data collection and analysis. All medical documentation remains variable between individuals and we cannot quantify unrecorded data, but the system utilized allowed for complete assessment of all recorded data on each research subject. As with any study evaluating growth, head circumference and length measurements are also variable as length boards were not used and measuring tape placement may vary between nursing staff. Some subjects were discharged prior to 36 weeks EGA, therefore, anthropometric measurements at 36 weeks EGA were not available. Likewise, lab values were also unavailable for these infants and could not be included in data analysis.
Alterations in human milk composition are continuous, so calculated nutrient compositions of fortified human milk may only serve as general estimations for our nutrient comparisons. Standard NICU nutrition practices are followed as consistently as possible, however feeding advancement may remain variable according to infant clinical status. Furthermore, the proportion of feedings as human milk or formula remained variable among each infant. In an ideal study, all enrolled infants would receive human milk only.
Though the incidence of NEC was statistically significant, it was not powered as a primary outcome for this study. We also suspect that diaper dermatitis was under-recorded during this study period, as our clinical experience suggests that diaper dermatitis is infrequently documented in the electronic medical record even when infants experience more serious medical complications. However, perceived worsening skin breakdown in our unit while using the ALHMF prompted development of a unit list of infants with diaper dermatitis. Unfortunately, not all of the infants recorded on the unit list had diaper dermatitis electronically documented as a medical problem. As there was no way to quantify these cases, these select infants were not coded positively for diaper dermatitis in this study. Therefore, our data analysis remains limited.
Use of the new ALHMF resulted in an increase in clinical complications and a decrease in growth as measured in both g/day and g/kg/day. To our knowledge, this is one of the first studies assessing use of the new ALHMF within a high acuity NICU without excluding infants with significant respiratory disease or low five-min APGAR scores. Further research with the ALHMF is needed to compare infant tolerance and outcomes among infants with a variety of gestational ages, weights, and increased clinical acuity.
The authors would like to thank Sarah Kennedy, Ashley Schlaepfer, and Allison Fischer for their contribution to data collection.
Conflicts of Interest
The authors declare no conflict of interest.
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© 2014 by MDPI, Basel, Switzerland This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). | <urn:uuid:53b809fd-b324-45f2-9970-5e54378d94fe> | CC-MAIN-2017-04 | http://www.mdpi.com/2072-6643/6/1/261/htm | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279650.31/warc/CC-MAIN-20170116095119-00428-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.912968 | 9,505 | 1.898438 | 2 |
PALERMO, Italy (Reuters) - A Sicilian judge on Wednesday ordered a trial for an Eritrean man accused of running a people smuggling network that sent thousands of migrants to Europe and many to their deaths during dangerous sea voyages to the continent.
Judge Alessia Geraci said Medhanie Tesfamariam Berhean would stand trial in Palermo, capital of Italy's southern island of Sicily, on Nov. 16 on charges of abetting illegal immigration and engaging in human trafficking.
Medhanie was arrested in May in Sudan and extradited to Italy, the European entry point for many migrants crossing the Mediterranean Sea in rickety boats from North Africa.
It was the first time a suspected trafficking kingpin was tracked down in Africa and brought to face justice in Italy since Europe's migration crisis started almost three years ago.
However, friends and family of Medhanie say it is a case of mistaken identity, arguing that he was an impoverished 29-year-old refugee with no criminal background, who was living quietly in Khartoum and seeking to join his siblings in the United States when he was arrested in a rundown cafe.
Medhanie denies all the charges.
His arrest was coordinated by Italy and Britain's National Crime Agency. They maintain they have the right man, but acknowledged that they initially got his name wrong and put out the photograph of another man.
More than 300,000 migrants and refugees have crossed the Mediterranean this year looking to reach Europe, according to the U.N. refugee agency. Some 3,210 migrants are reported to have died or gone missing while attempting the journey since Jan. 1.
(Reporting by Vladimiro Pantaleone writing by Philip Pullella; editing by Mark Heinrich) | <urn:uuid:a87b46e4-5842-4cce-b759-3215628e93a3> | CC-MAIN-2017-04 | http://www.metro.us/news/italy-sets-trial-for-suspected-african-human-smuggling-boss/Lmipiu---RTaCELl5BdQ2qQQN3i_I1A/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281746.82/warc/CC-MAIN-20170116095121-00283-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.969212 | 362 | 1.625 | 2 |
Design studio Raw Edges created this amazingly unique art installation titled 'Stack,' which features piles of drawers neatly and abstractly stacked atop one another. The towering structures are both elegant and deceiving.
Stack was created for the London Design Festival 2015. The exhibit boasts a variety of colorful structures that might seem random, but they each have a special flow within the stacked displays. Each tower uses a different set of drawers that are different colors. Many of the sculptures use colors from the same family of hues to ensure a cohesive appearance.
Additionally, the towers are stacked in a variety of styles. Some make use of clean erect lines, while others feature jutting edges that allow the tower to look as though it is about to topple over.
Artistically Stacked Drawers
More Stats +/-
Recycled Milk Jug Seating
Stackable Storage Stools
Ambidextrous Spring Scissors | <urn:uuid:6e4b0b56-cca6-4720-935a-4c5f878b1b2d> | CC-MAIN-2017-04 | http://www.trendhunter.com/trends/stack | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281574.78/warc/CC-MAIN-20170116095121-00018-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.929699 | 186 | 1.5625 | 2 |
Applying for Government Jobs
The Hong Kong SAR Government offers numerous job opportunities with many of them suitable for new graduates. Here you can learn about current government job vacancies for both civil service posts and non-civil service positions, the differences between them, and how to apply.
Where to Look for Government Job Vacancies
There are two types of Government job vacancies – civil service and non-civil service. Civil service vacancies are posts on the civil service establishment. Candidates selected for these jobs will be recruited on civil service terms of appointment and conditions of service. They will become civil servants upon appointment. Candidates appointed to non-civil service positions are not civil servants and will not be eligible for posting, promotion or transfer to any post within the civil service. They also have different terms of appointment and conditions of service.
Generally speaking, new recruits to either type of job must be permanent residents of the Hong Kong SAR. You can find both types of vacancies online. The Government Vacancies Enquiry System covers both civil service and non-civil service openings. The Interactive Employment Service of the Labour Department lists only non-civil service vacancies.More on Government job vacancies
Government job vacancies can generally be found on individual departmental websites.Departmental contact details
How to Apply for Government Job Vacancies
Most vacancies require applications to be made on Form G.F. 340. You can obtain a copy of this form at any Home Affairs Enquiry Centre of District Offices of the Home Affairs Department or any Job Centre of the Employment Services Division of the Labour Department.
The form can also be downloaded from the Civil Service Bureau’s website. For civil service vacancies, online application can also be made through this website.More on application procedures, including application form and online applicationHome Affairs Enquiry Centre numbers and addressesJob Centre numbers and addresses
Application can also be made on MyGovHK and the procedure is even made easier now. When an applicant submits an online application through his MyGovHK account, he may choose to use the “auto-fill” function to pre-fill the form with the personal data stored in his MyGovHK account on G.F. 340 On-line Application System.Online application through MyGovHK
Qualification Requirements and Assessment
The qualification requirements for civil service posts normally refer to qualifications from the Hong Kong education system or from local institutions. However, even if you hold non-local qualifications, you can still apply. You will be considered if your qualifications are assessed as comparable in standard to the entry qualification requirements of the post you are applying for.Statement on Qualifications Assessment
Selection for Appointment
Applicants for civil service posts and non-civil service positions may be required to sit for a written examination and/or other examinations conducted by the recruiting grades / departments to assess their competencies in the requisite skills and attributes and hence their suitability for appointment. The need for an examination is usually spelt out in the recruitment advertisements.
Language Proficiency Requirements
Applicants for civil service posts at degree or professional level are generally required to obtain either Level 2 or Level 1 in the Use of English (UE) and Use of Chinese (UC) papers in the Common Recruitment Examination (CRE), or equivalent.More on the CRE
Application for the CRE can be made on MyGovHK. When an applicant submits an online application through his MyGovHK account, he may also choose to use the “auto-fill” function to pre-fill the form with the personal data stored in his MyGovHK account on the CRE On-line Application System.Online application through MyGovHK
For civil service posts with general academic qualifications set below degree level, individual recruiting grades / departments will stipulate, in the relevant job advertisements, the language proficiency requirements of the posts concerned. In general, for posts with academic requirements set at Hong Kong Diploma of Secondary Education Examination (HKDSEE) / Hong Kong Certificate of Education Examination (HKCEE) level, applicants should attain at least Level 2 in Chinese Language and English Language in the HKDSEE / HKCEE, or equivalent.
Assessment of Basic Law (BL) Knowledge
For the purpose of heightening public awareness of the BL and promoting a culture of learning of BL in the community, applicants for civil service jobs will be assessed on their BL knowledge. The BL test result will be one of the considerations to assess the suitability of a candidate.More on the BL test and Sample Questions | <urn:uuid:fea71bfa-e307-49ed-ae2f-92c858b37215> | CC-MAIN-2017-04 | http://www.gov.hk/en/residents/employment/jobsearch/applygovtjobs.htm | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560279368.44/warc/CC-MAIN-20170116095119-00322-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.920349 | 918 | 1.6875 | 2 |
AFRICANGLOBE – Last week 53 South African students left for China to pursue studies at various universities on full scholarships from the Chinese government. In the 2014 calendar year, the Free State province sent 239 students to China.
Individual cities have scholarship agreements with China, as do higher-learning institutions, and there are also at least 100 – and possibly far more – South African students paying their own way at Chinese universities.
Nobody knows exactly what that total is, but there are at least 1 000 South Africans currently studying in China, making up perhaps as much as a tenth of all Africans studying in that country. The number is growing rapidly, not least because of the excellent feedback those in China give to their peers back home.
“Everyone I speak to, I say to them: ‘You have to apply; you have to come here,’?” said a South African studying in Fujian province. The student asked not to be identified. “I tell them how it is – it is better than I could have imagined.”
South African medical students in Cuba have complained about conditions there and about money shortages and even, on occasion, food. South African students in Brazil and Russia speak of language barriers and racism. By contrast, those in China on government scholarships report what they consider luxurious conditions, excellent teaching and a warm welcome.
As long as they remain students, those good conditions are likely to continue; students are explicitly considered future agents of “soft power” for China on the African continent, analysts agree, and treating them well is part of a long-term strategy.
Should those students think about staying on in China as professionals, they may find the environment less conducive. Africans in China have been finding life increasingly difficult over the past seven years, and the current upheaval in the Chinese economy could spell trouble.
“It is normal for countries with economic problems to blame immigrants for some of their woes, so I wouldn’t be surprised if the discourse evolves in this direction,” said Adams Bodomo, professor of African studies at the University of Vienna, on possible changes in attitude.
In 2012, while at the University of Hong Kong, Bodomo published the first comprehensive book on Africans in China, as opposed to the reams written about China in Africa.
In it, he highlighted how concerned Africans are about intensifying immigration crackdowns, a phenomenon that seems to have started in the run-up to the 2008 Olympic Games in Beijing and since accelerated.
Before then, immigration was handled in rather slapdash fashion; even though Africans flocked to some centres in China in their hundreds of thousands, those numbers were minuscule compared to the millions of Chinese flowing into Africa.
“Among the problems China encountered in its rapid development, immigration problems remain marginalised and have not raised serious concern,” one research paper published in South Africa stated in 2012. In China itself, however, Bodomo and his team were even then reporting on a different reality.
Those Africans in China who could plausibly do so, such as white South Africans or Arab North Africans, would claim not to be from the continent unless it suited their specific purpose.
Africans without that option reported being singled out and harassed, “disproportionately selected at border checkpoints for extra inspections by customs officials and constantly asked to produce their identity papers”.
Considering the number of Chinese immigrants coming into various African countries at the time – and what Africans considered the good treatment those immigrants received – this caused some unhappiness.
“There is a saying among the Dagaaba of northern Ghana,” Bodomo wrote in 2012, “that if a man visits his friend and his friend roasts a fowl for him to eat, the man is expected to show the same hospitality on a return visit by also roasting a fowl for his friend. It seems that there is hardly anyone roasting fowls for Africans in China.”
The experience is not universal: scholars and analysts point out that Chinese reactions to Africans are mixed, and anything from geography to class will determine whether that reaction is xenophobic, tolerant or somewhere in between.
For traders and businesspeople, however – as opposed to students – available data suggests that experiences of China tend towards the negative, coloured by language barriers, racist incidents and the like.
South Africans, used to a slightly different standing from other Africans when abroad, are no exception. “When I tell people I’m from South Africa, they say: ‘Ah, you are African, yes,’” says the South African student in Fujian province. “Nowhere is South Africa special … I may as well be from Nigeria or Mozambique; it’s the same here.”
Like students, African businesspeople tend to remain in China for short periods, seldom more than three years. Those who remain in the country longer, in contravention of strict visa requirements, find themselves enmeshed in a patchwork of regulations that require businesses in some areas to check foreigners’ visas before doing business with them.
And so a steady flow of traders return from China with largely negative sentiments towards that country, even as a smaller group of students return with glowing reports and a likelihood of welcome future investment by, and trade with, China.
What net influence that has on African sentiment towards China is not clear; attitudes vary enormously between African countries and from year to year, and the concerted scholarship programme is not yet old enough to show its effect.
If, however, economic troubles continue in China, there is the possibility of an equalisation of attitudes between some African countries and China: African countries where Chinese immigrants are seen as competitors for scarce resources and as strangers to be feared.
Already there are early signs of stories doing the rounds in China that are eerily reminiscent of persistent urban legends in places like Angola, legends that paint Chinese immigrants as mercenary and rapacious.
“[Chinese] friends tell me there is one story they keep hearing about how Africans come here with Aids and rape woman to spread it” as a form of biological-economic warfare, the Fujian student says. “They laugh at it. For now.”
By: Phillip de Wet | <urn:uuid:7d5314d0-5f4d-4f91-a9ef-d084d71d01c8> | CC-MAIN-2017-04 | https://www.africanglobe.net/africa/china-africans-home/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280791.35/warc/CC-MAIN-20170116095120-00365-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.968447 | 1,291 | 2.03125 | 2 |
NEW DELHI, India — They say it takes a thief to catch a thief, but India’s Delhi Metro has hired a monkey to frighten off other monkeys from boarding trains and upsetting passengers.
C'mon — what's not to like?
Hoof it over to Facebook to join the weird news herd.
- C'mon — what's not to like?
In an effort to keep monkeys out of the New Delhi subways, authorities have called in one of the few animals known to scare the creatures — a fierce-looking primate called the langur, the Hindustan Times newspaper reported Wednesday.
The decision to hire a langurwallah — a man who trains and controls the langurs — came after a monkey got into a metro car June 9, the newspaper reported.
In that incident, a monkey boarded a train at the underground Chawri Bazaar station and reportedly scared passengers by scowling at them for three stops. It then disembarked at Civil Lines station.
Passengers had to be moved to another car while staff chased the dexterous creature, causing delays.
The Delhi Metro Rail Corporation says it hopes the new hire will avert a repeat of that episode.
“It started working about a month ago and since then we’ve not had a single incident,” said Anuj Dayal, a metro spokesman.
The langur handler is being paid a retainer of India rupees 6,900 ($160) a month, and “he will be called whenever there is a monkey problem,” Dayal was quoted as saying.
“There are too many monkeys,” Dayal was quoted as saying.
Langur monkeys are similarly employed around the grounds of parliament and some government buildings in New Delhi.
© 2013 msnbc.com | <urn:uuid:7d6f54f4-bdf6-45df-8fce-394be6be4795> | CC-MAIN-2017-04 | http://www.nbcnews.com/id/14121007/ns/world_news-weird_news/t/india-train-company-turns-monkey-business/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280266.9/warc/CC-MAIN-20170116095120-00502-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.965936 | 377 | 1.804688 | 2 |
Ayala Museum presents
Advanced Storywriting for Writers & Illustrators
with Gabriela Lee
4, 11, and 18 2015 | 2:00 – 5:00 PM
27 July | 6:00 – 9:00 PM
Ever dreamed of making a picture book for kids? Here’s your chance to put pen to paper and make your dreams take flight. This advanced-level workshop is open to writers and/or illustrators to create and collaborate on a picture book project for child readers.
The workshop fee is inclusive of handouts, materials, snacks, a certificate, one day admission to the museum and one day free access to the library.
Gabriela Lee was 17 when she wrote her first children’s book, La-on and the Seven-Headed Dragon, which was illustrated by her mother, Marcy Dans-Lee and published by Adarna Books. Now, her poems and short stories have been published in the Philippines, Singapore, and the United States. Her latest work has been included in Kaleidoscope, an anthology of diverse young adult speculative fiction published by Twelfth Planet Press. She received her master’s degree in Literary Studies from NUS (National University of Singapore), and she currently teaches creative writing, literature, and composition at the English department at UP Diliman. You can find her online at https://about.me/gabrielalee.
P 4,000 Regular
P 3,600 Members, AGC employees
For inquiries and reservations:
CALL: 759 82 88
LOOK FOR: Marj Villaflores, or any education associate | <urn:uuid:141edf4e-5e93-4631-96b2-ca39b20bddd2> | CC-MAIN-2017-04 | http://www.ayalamuseum.org/2015/06/19/advanced-storywriting-for-writers-and-illustrators/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280730.27/warc/CC-MAIN-20170116095120-00247-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.946699 | 337 | 2.15625 | 2 |
Online degrees are the way forward for training. Every one of us learn how pricey going to standard colleges and universities are. The educational costs charges are sky high especially on lessons that handles health and treatments. In addition to that, other miscellaneous school costs increase the price also. You also have to incorporate your transport service fees, dinner allowances and even guides, notebooks and school products you will end up expected to buy. Rather than guides and research material, there are a variety of online solutions and online resources that are not only totally free but could equip you because of the needs you will need for distance learning.
No matter how much you have stored up for college possibly university based or online, you may still wind up experiencing financial problems. You could possibly even question if the reasonably priced online degree can be done? The answer is indeed, given that in comparison to a degree from your college campus dependent university or college, pursuing an online degree will be the more cost-effective choice.
Aside from the previously mentioned specifics that will make an online degree inexpensive, there are a variety of suggestions you could do to follow a degree in the most affordable way.
School Funding: Register for schools which are accredited and who offer you federal government student money for college that you could be eligible for a. Be aware that by getting private personal loans, you could possibly find yourself spending additional money than you actually intended to.
Boss Assist: There are plenty of firms today that will help their staff members follow their online degrees. They fund staff members simply because they already know that it will probably be a wise investment on their behalf. Further expertise implies much more qualified staff members that could work better, hence benefiting both parties.
Low priced open public schools or educational institutions: I am aware that we are discussing online degrees, nevertheless these low priced universities at times offer lam bang gia re too. Other general public educational institutions at times waive some educational costs charges for people students who are enrolling online.
I understand how a lot of a plus it is getting a cost-effective online degree. Not merely will it be an easy way for you to obtain advancement inside your schooling. It will be a main consider getting you the finest possible career possibilities. Because there are a lot of positive aspects, we need to discuss the drawbacks of getting them as well. Beware of some companies that create as approved and legitimate universities for online training. They mean to give away deceptive degrees simply to acquire people’s money. Without accreditation, the degree contains no educational or other importance. Armed with this information and facts, the one thing left to do is choose what online degree you need to focus on, investigate all possible possibilities, encourage oneself and enjoy the whole experience for that effects will provide you with a much brighter future ahead. | <urn:uuid:93947cf7-1d32-4934-8c83-21c6c3f8baee> | CC-MAIN-2022-33 | http://www.centre-equestre-contance.com/inexpensive-online-degrees-the-secrets-and-techniques-you-have-to-know.html | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572286.44/warc/CC-MAIN-20220816090541-20220816120541-00278.warc.gz | en | 0.962696 | 561 | 2.03125 | 2 |
10 steps to travel writing that engages
Report on Travel Writing seminar at TBEX 12
“If you just want to write about yourself, it’s not travel writing,” said Spud Hilton, editor of the San Francisco Chronicle travel section. “It’s called a memoir.” Spud was speaking with Stephanie Yoder of the travel blog Twenty Something Travel at the Travel Blogger’s Exchange conference, popularly known as TBEX, in Colorado, June 2012. Together, they were presenting the one and only travel writing seminar at TBEX, 10 Steps to Writing that Better Engages and Keeps Your Readers.
I had the pleasure of introducing the seminar, and I said that I thought it was the most important one on the agenda; and that without a story, you’ve got nothing. Like Spud and Stephanie, I feel strongly that quality writing is important, and that learning to tell a story is essential to being a travel writer / blogger.
What is quality travel writing / blogging? They started the seminar with this definition:
- it meets the informational or emotional needs of the reader
- it entertains, informs or inspires the reader
- it satisfies the writer
Spud made a passionate plea to the audience to get them to rethink travel blogging: “You don’t want to just get readers, you want to keep them,” he said. “They will get bored of you a lot faster than of the places you go. And remember that you grossly overestimate your ability to write about a place. When you were there, you experienced it with all five senses. But your readers don’t have that experience; they are using only one sense. You have to convey it.”
Travel writing and the art of the story: Have a point
Spud and Stephanie then went on to present their Top 10 travel writing tips — but to me, tip #1 seems to be the most important.
- Have a point. Without a point (or premise) you are re-hashing your diary, Spud said. You need to make a bigger point than simply you were there. He gave the example of traveling in wine country and then writing a piece about what ELSE you can do there, aside from wine related activities.
- Prose is the frosting. The story is the cake. (See tip #1.) There’s no point in describing a setting if you don’t have a point.
- Understand structure. At the very least, you can use the standard five-section “essay” format: Lead, premise (aka nut or nut graph), scene 1, scene 2, scene 3, walk-off.
- Be unique or original. You are not the first person to go up the Eiffel Tower or even swim with sea lions in the Galapagos. You need to put a fresh spin on your travel experiences to make your writing fresh and engaging.
- Organize content in a digestible way. Break up text, add headings, use lists. Be succinct or be engaging.
- Cultivate a unique voice and personality. Travel bloggers, in particular, need to do this to stand out. It has been said many time, though perhaps especially by Gary Arndt, people follow personalities online.
- Be creative with context. In other words, if you want to express something like a measurement, use a compelling image or example. For example, instead of saying x cubic whatevers of water, say it was more than the combined flow of all the rivers of the world. To get creative measurements, type the measure into Google and “you will get something weird,” said Spud.
- Proofread your work. You cannot come off as a professional writer if your copy is full of typos and grammatical mistakes. Stephanie suggests reading your work aloud and having a second set of eyes look at it.
- Grab attention immediately! You need to grab the reader in seconds. The first paragraph is the most important. Give them a reason to care.
- Fact-check your work. “I cannot emphasize this enough,” said Spud. “If your mother says she loves you, check it out.” And don’t trust Wikipedia or the tourism industry. Check the facts you are given. You might not have to go to the lengths in this video below, but check everything out.
Finally, Stephanie and Spud’s plea for …
- using “fewer” not “less,” if a specific number is involved
- being accurate instead of using attribution (the word allegedly doesn’t protect anybody from anything)
- reading William Zinsser “On Writing Well” and Strunk and White’s “Elements of Style”
- not using a quote for a lead
- using dialogue only if it advances the story (and be accurate, don’t make it up!)
- understanding that good writing is important to blog readers
- writing to intrigue people rather than writing for SEO
- editing: you need an editor (try creating a partnership or circle of writers and editing each other’s work).
If you enjoyed this post, you can….
Sign up to The Travel Newsletter in the sidebar and follow Breathedreamgo on all social media platforms including Instagram, TripAdvisor, Facebook, Pinterest, and Twitter. Thank you! | <urn:uuid:bbebce4c-986d-4321-b0e5-fcb08f4cc4ed> | CC-MAIN-2022-33 | https://breathedreamgo.com/top-10-travel-writing-tips/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571502.25/warc/CC-MAIN-20220811194507-20220811224507-00067.warc.gz | en | 0.941892 | 1,141 | 1.523438 | 2 |
In this post, I share with you 5 easy life hacks to boost your productivity, without burning out.
TABLE OF CONTENT
- Think in a solution-oriented way
- Define what brings you closer to your goal
- Choose your time wisely
- 90 minutes of focused work
- Use apps to help you stay focused
- 4 apps to increase your productivity
1. THINK IN A SOLUTION-ORIENTED WAY
From time to time we all face problems in life and business.
That’s just part of the game.
They can literally paralyze us and can affect our productivity.
Whenever we face a problem, we are confronted with a mixture of overwhelm and disconnection of our flow.
This can lead to feeling stuck in a particular situation.
Whenever we are focusing more on the problem instead of on the solution, we feel even more stuck.
Approaching a problem in a solution-oriented way, however, puts us literally into another mindset.
We tap into the creative side of our brain and start focusing on finding solutions, instead of digging deeper into our problem.
This change of approaching problems in a positive way has the effect that we come into motion.
We start moving towards the solution and consequently away from our problem.
And as already Albert Einstein said: “ We cannot solve problems with the same thinking we used when we created them. “
2. DEFINE WHAT BRINGS YOU CLOSER TO YOUR GOAL
Listen, watch and do the things that bring you closer to your goal.
Being mindful of your activities will help move you towards your goals with ease.
Say no to all the things that aren’t in alignment with your greater vision and with your goals.
You might feel uncomfortable saying no at first but remember that every time you are saying no to something, you don’t care about, you at the same time say yes to yourself and to your goals!
Our time on this planet is limited therefore it’s really important to make sure we use it mindfully.
3. CHOOSE YOUR TIME WISELY
Robin Sharma once stated in a talk, that “Life is a limited resource, treat it like it”.
He also said a great example which I want to share here with you because I think it’s a game-changer.
So here it comes in my words.
We often hear from people who don’t realize their goals and dreams the argument of not having enough time for it.
At the same time, we see the same people spending every evening after work 4-5 hours in front of the tv.
It’s nothing wrong with watching tv.
At the same time, however, the argument of not having enough time is not really true when they have time to spend it in front of the tv.
It’s then just a question of priority.
They have the time they just don’t use it to pursue their dreams.
If we calculate 4-5 hours per day of watching tv 5 times a week.
We come to the result of 20-25 hours per week of free time.
This is like a part-time job that could be used to pursue their goals.
4. 90 MINUTES OF FOCUSED WORK
This concept is about using the first 90 minutes of every day solely for focused work towards your goal.
We usually wake up in the morning energized and ready to rock the world.
So do it!
This energy and clear mind is a great starting point for focused working.
It’s more likely that we get way more done with a clear and relaxed mind than throughout the day.
Creating a morning routine with a focused time for work can help you achieve more goals in a relaxed way.
Successful people don’t just go with the flow.
Instead, they make a plan and make smart use of their time.
They plan time to tackle their tasks which brings them closer to their goals every single day.
Use the templates from the printable Go For Your Dreams Planner to get clear of your future vision and turn it into actionable goals.
5. USE APPS TO HELP YOU STAY FOCUSED
Being distracted while working is nowadays one of our biggest productivity killers.
However, there are great apps out there that can help you stay focused to get things done.
They prevent you from being distracted by social media and all sorts of websites you like to check out while you are trying to get things done.
4 APPS TO INCREASE YOUR PRODUCTIVITY
The ability to be connected and online all the time can be a blessing and a curse at the same time.
Especially when we want to accomplish something and work with a high focus.
The temptation of browsing the web and getting distracted by something else is huge.
Social media certainly contributes to this.
However, we don’t have to turn away from social media completely.
It’s just important that we use our time and internet consciously.
There are 4 amazing apps that can help you stay focused and get more done.
The creme de la creme herefore is the Freedom App!
1. THE FREEDOM APP
This awesome app blocks for you all the sites you are most likely distracted by.
Whenever you want to work with focus and get things done you can use the freedom app which blocks for you the sites you are most likely distracted by.
You can, for example, tell The Freedom App that you want to have Facebook-free time for the next 5 hours.
This app then blocks Facebook for you for 5 hours and you have no chance to log in to Facebook during this time period.
You can use this app on your phone and on your laptop!
2. WEB TIME TRACKER
Another tool you can use is called web time tracker.
With this tool, you can easily track where you spend your time online.
With the chrome extension, you can also see in detail how much time you spend on each site.
This tool gives you a great overview of seeing where you are getting distracted the most online.
It allows you to check your daily stats as well as the most visited domains.
Web Time Tracker helps you become more aware of the time you spend online.
3. TOP TAL TRACKER
Another great tool to boost your productivity and help you stay focused is Top Tal Tracker.
This tool allows you to set up daily project goals and let you check how much you stick to them.
Top Tal tracker tracks your time and gives you every 10 minutes a visual graph of what you are doing right now.
If you are like me and love to browse through social media and Pinterest, although you started working on sth else → This tool reminds you to see visually what you are doing.
It let you see how much you are sticking to the task you were actually starting to do.
4. STAY FOCUSD
Stay Focusd is another great Chrome extension for more productivity and mindful surfing.
This tool also helps you staying focused whenever you work online and usually get distracted by Instagram, Facebook or Pinterest.
With stay focusd, you can set yourself a time limit per day on social media.
Once you hit the time limit it will block you from the page for the entire day.
This way you can’t be tempted getting distracted by these sites.
Download the free Go For Your Dreams Guide and learn about the steps you have to take to achieve your goals.
Use the templates from the printable Go For Your Dreams Planner and turn your dream into an actionable plan. | <urn:uuid:fbadb4b1-16f6-43c2-b5b8-dfea98c56f21> | CC-MAIN-2022-33 | http://lillaliptak.com/5-best-productivity-tips/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573699.52/warc/CC-MAIN-20220819131019-20220819161019-00271.warc.gz | en | 0.93783 | 1,604 | 1.617188 | 2 |
The use of Infinite Banking Strategies to increase chances to qualify for college funding (FAFSA), even if income is over six figures.
Traditional IRA (a tax-deferred account) – Contributions are made with pre-tax dollars and contributions can be tax deductible. Money compounds tax free until funds are withdrawn.
Roth IRA (a tax-free savings plan) – Contributions are made with after-tax dollars and are not tax deductible. Money compounds tax free and all funds withdrawn are also tax free. Earned income must fall within the MAGI (Modified Adjusted Gross Income) limits to qualify for account.
SEP (Simplified Employee Pension) – Designed for self-employed or small business owners with up to 25 employees. Plan allows for high annual contributions which are tax deductible and all money compounds tax free until funds are withdrawn.
Clockwork Financial structures Traditional, Roth, and SEP.
A contract with an insurance company that promises periodic payments keyed in a specified manner to a stock market index. Unlike variable annuities, fixed-indexed annuities specify a guaranteed minimum return. These contracts may also specify an upper limit (cap) on the return that is paid. | <urn:uuid:06b14bc5-5e4f-4d71-979d-71942f452889> | CC-MAIN-2022-33 | https://clockworkfinancial.webs.com/financial-strategies | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573118.26/warc/CC-MAIN-20220817213446-20220818003446-00670.warc.gz | en | 0.932871 | 245 | 1.890625 | 2 |
Sport scouters are seeking holistic athletes and Angela Young, Founder and President of Kids in Control Systems (KICS) prepares young athletes to meet this challenge.
At a recent presentation at North Village Community Club’s Board Meeting, Angela shared how in eight years of operating KICS, she has coached some of Bermuda’s upcoming and brightest young football and cricket talent.
In fact, some of these clients have been scouted for full scholarships at high schools in the United States and London. And, now some have full football scholarships at D1 and D2 level universities in the United States.
“While I had the students at ages 12 through to 14 in some cases, the parents remain in touch with me and give me updates,” explained Angela. “Now, they are 16, 18 and 20 years old pursuing their dreams of becoming professional footballers. All of them have received full scholarships based on both their high academics and outstanding athletic abilities.”
As the competition increases, some clubs are looking at diverse opportunities to ensure their players have an edge—on and off the field.
“North Village Community Club (NVCC) had the pleasure of meeting with Ms. Angela Young this past Tuesday evening at our Board Meeting. We had the opportunity to hear and learn first-hand what her KICS System Program is all about,” shared Shervin Dill, NVCC President. “Angela did an excellent presentation detailing all the exciting opportunities and holistic benefits her program can provide to our Youth Program at NVCC. The Board was very impressed with her energy and methodology of teaching, and we are looking forward to partnering with Angela and the KICS Systems team.”
Angela launched KICS in May 2014, after assisting her own daughter, Kameron, strengthen her executive functioning skills while at Bermuda High School for Girls. Today, Kameron has evolved as one of Bermuda’s next ‘STEM girls to watch’ as she is proficient in coding, fluent in Spanish and is currently pursuing her Bachelors of Science in Biomedical Engineering at Queen Mary University of London.
Her flag ship program, Note-taking & Studying Strategies, is highly sought after by parents. Angela has worked with over 300 students from ages M1 and up, across Bermuda’s public and private schools since its launch in May 2014.
“A KICS Workshop is like no other,” shared the Founder. “Students do not know what to expect but at the end of the six weeks, they leave with practical tips and tools which set them apart from the rest. I develop the whole child and I tailor the lessons to meet them where they are at KICS gives an edge.”
“I think that is what NVCC is looking for,” Angela further explained. “The Executive understand that they must employ new strategies to truly make a unique impact on their players and their families as a whole. North Village has a long history of producing excellent athletes and I am honored to collaborate with the Club to help mold the next generation of Bermuda’s athletes.
NVCC is the first community club to partner with KICS and I am very excited.”
The next Note-taking & Studying Strategies Workshop kicks off on January 29th and spots are going quickly. There is a special offer which expires on January 28th at 5 pm. For registration details, parents are encouraged to visit the website at www.kicssystems.com. | <urn:uuid:ccd62bb8-d740-4bdf-8a56-244554020e95> | CC-MAIN-2022-33 | http://islandstats.com/sport.asp?sport=42&photoevent=0&assoc=1&newsid=55574 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571234.82/warc/CC-MAIN-20220811042804-20220811072804-00074.warc.gz | en | 0.972051 | 724 | 1.71875 | 2 |
WINDSOR LOCKS - The New England Air Museum recently received a $1,000 grant from Praxair Incorporated to help support the delivery of the museum's SOAR for Science program to Suffield Middle School students. The museum's SOAR for Science program focuses on improving the math and science skills of students, as well as exposing students to the many career opportunities in the STEM (Science, Technology, Engineering and Math) fields. Thanks to the generosity of sponsors, such as Praxair, students are able to participate in the SOAR for Science program at no cost to the school district.
The New England Air Museum is owned and operated by the Connecticut Aeronautical Historical Association, a private, non-profit educational institution organized in 1959. Admission is $12 for ages 12 and older, $11 for seniors 65 and older and $6.50 for ages 4 to 11. Children younger than 3 are admitted free. For more information, visit http://www.neam.org or call 860-623-3305. | <urn:uuid:3502fe9b-713e-4122-8d8a-602843c124cb> | CC-MAIN-2017-04 | http://www.courant.com/rnw-wl-0814-windsorlocks-airmuseumgrant-20140807-story.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281353.56/warc/CC-MAIN-20170116095121-00063-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.943838 | 213 | 2.078125 | 2 |
Emerging evidence from a number of laboratories indicates that humans have the ability to identify fatty acids in the oral cavity, presumably via fatty acid receptors housed on taste cells. Previous research has shown that an individual's oral sensitivity to fatty acid, specifically oleic acid (C18:1) is associated with body mass index (BMI), dietary fat consumption, and the ability to identify fat in foods. We have developed a reliable and reproducible method to assess oral chemoreception of fatty acids, using a milk and C18:1 emulsion, together with an ascending forced choice triangle procedure. In parallel, a food matrix has been developed to assess an individual's ability to perceive fat, in addition to a simple method to assess fatty food liking. As an added measure tongue photography is used to assess papillae density, with higher density often being associated with increased taste sensitivity.
22 Related JoVE Articles!
Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Institutions: University of California, San Francisco, Veterans Affairs Medical Center, San Francisco, Veterans Affairs Medical Center, San Francisco.
The vascular endothelium is a monolayer of cells that cover the interior of blood vessels and provide both structural and functional roles. The endothelium acts as a barrier, preventing leukocyte adhesion and aggregation, as well as controlling permeability to plasma components. Functionally, the endothelium affects vessel tone.
Endothelial dysfunction is an imbalance between the chemical species which regulate vessel tone, thombroresistance, cellular proliferation and mitosis. It is the first step in atherosclerosis and is associated with coronary artery disease, peripheral artery disease, heart failure, hypertension, and hyperlipidemia.
The first demonstration of endothelial dysfunction involved direct infusion of acetylcholine and quantitative coronary angiography. Acetylcholine binds to muscarinic receptors on the endothelial cell surface, leading to an increase of intracellular calcium and increased nitric oxide (NO) production. In subjects with an intact endothelium, vasodilation was observed while subjects with endothelial damage experienced paradoxical vasoconstriction.
There exists a non-invasive, in vivo
method for measuring endothelial function in peripheral arteries using high-resolution B-mode ultrasound. The endothelial function of peripheral arteries is closely related to coronary artery function. This technique measures the percent diameter change in the brachial artery during a period of reactive hyperemia following limb ischemia.
This technique, known as endothelium-dependent, flow-mediated vasodilation (FMD) has value in clinical research settings. However, a number of physiological and technical issues can affect the accuracy of the results and appropriate guidelines for the technique have been published. Despite the guidelines, FMD remains heavily operator dependent and presents a steep learning curve. This article presents a standardized method for measuring FMD in the brachial artery on the upper arm and offers suggestions to reduce intra-operator variability.
Medicine, Issue 92, endothelial function, endothelial dysfunction, brachial artery, peripheral artery disease, ultrasound, vascular, endothelium, cardiovascular disease.
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Institutions: The Methodist Hospital Research Institute, Houston, The Methodist Hospital Research Institute, Houston.
Brown adipose tissue (BAT) differs from white adipose tissue (WAT) by its discrete location and a brown-red color due to rich vascularization and high density of mitochondria. BAT plays a major role in energy expenditure and non-shivering thermogenesis in newborn mammals as well as the adults 1
. BAT-mediated thermogenesis is highly regulated by the sympathetic nervous system, predominantly via β adrenergic receptor 2, 3
. Recent studies have shown that BAT activities in human adults are negatively correlated with body mass index (BMI) and other diabetic parameters 4-6
. BAT has thus been proposed as a potential target for anti-obesity/anti-diabetes therapy focusing on modulation of energy balance 6-8
. While several cold challenge-based positron emission tomography (PET) methods are established for detecting human BAT 9-13
, there is essentially no standardized protocol for imaging and quantification of BAT in small animal models such as mice. Here we describe a robust PET/CT imaging method for functional assessment of BAT in mice. Briefly, adult C57BL/6J mice were cold treated under fasting conditions for a duration of 4 hours before they received one dose of 18
F-Fluorodeoxyglucose (FDG). The mice were remained in the cold for one additional hour post FDG injection, and then scanned with a small animal-dedicated micro-PET/CT system. The acquired PET images were co-registered with the CT images for anatomical references and analyzed for FDG uptake in the interscapular BAT area to present BAT activity. This standardized cold-treatment and imaging protocol has been validated through testing BAT activities during pharmacological interventions, for example, the suppressed BAT activation by the treatment of β-adrenoceptor antagonist propranolol 14, 15
, or the enhanced BAT activation by β3 agonist BRL37344 16
. The method described here can be applied to screen for drugs/compounds that modulate BAT activity, or to identify genes/pathways that are involved in BAT development and regulation in various preclinical and basic studies.
Molecular Biology, Issue 69, Neuroscience, Anatomy, Physiology, Medicine, Brown adipose tissue, mice, 18F-Fluorodeoxyglucose, micro-PET, PET, CT, CT scan, tomography, imaging
Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children
Institutions: Academic Medical Center - University of Amsterdam, Public Health Service of Amsterdam (GGD), VU University, VU University Medical Center, VU University, VU University Medical Center.
The autonomic nervous system (ANS) controls mainly automatic bodily functions that are engaged in homeostasis, like heart rate, digestion, respiratory rate, salivation, perspiration and renal function. The ANS has two main branches: the sympathetic nervous system, preparing the human body for action in times of danger and stress, and the parasympathetic nervous system, which regulates the resting state of the body.
ANS activity can be measured invasively, for instance by radiotracer techniques or microelectrode recording from superficial nerves, or it can be measured non-invasively by using changes in an organ's response as a proxy for changes in ANS activity, for instance of the sweat glands or the heart. Invasive measurements have the highest validity but are very poorly feasible in large scale samples where non-invasive measures are the preferred approach. Autonomic effects on the heart can be reliably quantified by the recording of the electrocardiogram (ECG) in combination with the impedance cardiogram (ICG), which reflects the changes in thorax impedance in response to respiration and the ejection of blood from the ventricle into the aorta. From the respiration and ECG signals, respiratory sinus arrhythmia can be extracted as a measure of cardiac parasympathetic control. From the ECG and the left ventricular ejection signals, the preejection period can be extracted as a measure of cardiac sympathetic control. ECG and ICG recording is mostly done in laboratory settings. However, having the subjects report to a laboratory greatly reduces ecological validity, is not always doable in large scale epidemiological studies, and can be intimidating for young children. An ambulatory device for ECG and ICG simultaneously resolves these three problems.
Here, we present a study design for a minimally invasive and rapid assessment of cardiac autonomic control in children, using a validated ambulatory device 1-5
, the VU University Ambulatory Monitoring System (VU-AMS, Amsterdam, the Netherlands, www.vu-ams.nl).
Medicine, Issue 74, Neurobiology, Neuroscience, Anatomy, Physiology, Pediatrics, Cardiology, Heart, Central Nervous System, stress (psychological effects, human), effects of stress (psychological, human), sympathetic nervous system, parasympathetic nervous system, autonomic nervous system, ANS, childhood, ambulatory monitoring system, electrocardiogram, ECG, clinical techniques
Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
Institutions: Tufts University Cummings School of Veterinary Medicine, Manchester Metropolitan University.
Exposure to chronic stress is a reliable predictor of depressive disorders, and social stress is a common ethologically relevant stressor in both animals and humans. However, many animal models of depression were developed in males and are not applicable or effective in studies of postpartum females. Recent studies have reported significant effects of chronic social stress during lactation, an ethologically relevant and effective stressor, on maternal behavior, growth, and behavioral neuroendocrinology. This manuscript will describe this chronic social stress paradigm using repeated exposure of a lactating dam to a novel male intruder, and the assessment of the behavioral, physiological, and neuroendocrine effects of this model. Chronic social stress (CSS) is a valuable model for studying the effects of stress on the behavior and physiology of the dam as well as her offspring and future generations. The exposure of pups to CSS can also be used as an early life stress that has long term effects on behavior, physiology, and neuroendocrinology.
Behavior, Issue 76, Neuroscience, Neurobiology, Physiology, Anatomy, Medicine, Biomedical Engineering, Neurobehavioral Manifestations, Mental Health, Mood Disorders, Depressive Disorder, Anxiety Disorders, behavioral sciences, Behavior and Behavior Mechanisms, Mental Disorders, Stress, Depression, Anxiety, Postpartum, Maternal Behavior, Nursing, Growth, Transgenerational, animal model
Biochemical and High Throughput Microscopic Assessment of Fat Mass in Caenorhabditis Elegans
Institutions: Massachusetts General Hospital and Harvard Medical School, Massachusetts Institute of Technology.
The nematode C. elegans
has emerged as an important model for the study of conserved genetic pathways regulating fat metabolism as it relates to human obesity and its associated pathologies. Several previous methodologies developed for the visualization of C. elegans
triglyceride-rich fat stores have proven to be erroneous, highlighting cellular compartments other than lipid droplets. Other methods require specialized equipment, are time-consuming, or yield inconsistent results. We introduce a rapid, reproducible, fixative-based Nile red staining method for the accurate and rapid detection of neutral lipid droplets in C. elegans
. A short fixation step in 40% isopropanol makes animals completely permeable to Nile red, which is then used to stain animals. Spectral properties of this lipophilic dye allow it to strongly and selectively fluoresce in the yellow-green spectrum only when in a lipid-rich environment, but not in more polar environments. Thus, lipid droplets can be visualized on a fluorescent microscope equipped with simple GFP imaging capability after only a brief Nile red staining step in isopropanol. The speed, affordability, and reproducibility of this protocol make it ideally suited for high throughput screens. We also demonstrate a paired method for the biochemical determination of triglycerides and phospholipids using gas chromatography mass-spectrometry. This more rigorous protocol should be used as confirmation of results obtained from the Nile red microscopic lipid determination. We anticipate that these techniques will become new standards in the field of C. elegans
Genetics, Issue 73, Biochemistry, Cellular Biology, Molecular Biology, Developmental Biology, Physiology, Anatomy, Caenorhabditis elegans, Obesity, Energy Metabolism, Lipid Metabolism, C. elegans, fluorescent lipid staining, lipids, Nile red, fat, high throughput screening, obesity, gas chromatography, mass spectrometry, GC/MS, animal model
Barnes Maze Testing Strategies with Small and Large Rodent Models
Institutions: University of Missouri, Food and Drug Administration.
Spatial learning and memory of laboratory rodents is often assessed via navigational ability in mazes, most popular of which are the water and dry-land (Barnes) mazes. Improved performance over sessions or trials is thought to reflect learning and memory of the escape cage/platform location. Considered less stressful than water mazes, the Barnes maze is a relatively simple design of a circular platform top with several holes equally spaced around the perimeter edge. All but one of the holes are false-bottomed or blind-ending, while one leads to an escape cage. Mildly aversive stimuli (e.g.
bright overhead lights) provide motivation to locate the escape cage. Latency to locate the escape cage can be measured during the session; however, additional endpoints typically require video recording. From those video recordings, use of automated tracking software can generate a variety of endpoints that are similar to those produced in water mazes (e.g.
distance traveled, velocity/speed, time spent in the correct quadrant, time spent moving/resting, and confirmation of latency). Type of search strategy (i.e.
random, serial, or direct) can be categorized as well. Barnes maze construction and testing methodologies can differ for small rodents, such as mice, and large rodents, such as rats. For example, while extra-maze cues are effective for rats, smaller wild rodents may require intra-maze cues with a visual barrier around the maze. Appropriate stimuli must be identified which motivate the rodent to locate the escape cage. Both Barnes and water mazes can be time consuming as 4-7 test trials are typically required to detect improved learning and memory performance (e.g.
shorter latencies or path lengths to locate the escape platform or cage) and/or differences between experimental groups. Even so, the Barnes maze is a widely employed behavioral assessment measuring spatial navigational abilities and their potential disruption by genetic, neurobehavioral manipulations, or drug/ toxicant exposure.
Behavior, Issue 84, spatial navigation, rats, Peromyscus, mice, intra- and extra-maze cues, learning, memory, latency, search strategy, escape motivation
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Institutions: University Hospitals Leuven, Monash University, Victoria, Australia, Katholieke Universiteit Leuven, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER).
Fetal intrauterine growth restriction (IUGR) results in abnormal cardiac function that is apparent antenatally due to advances in fetoplacental Doppler ultrasound and fetal echocardiography. Increasingly, these imaging modalities are being employed clinically to examine cardiac function and assess wellbeing in utero
, thereby guiding timing of birth decisions. Here, we used a rabbit model of IUGR that allows analysis of cardiac function in a clinically relevant way. Using isoflurane induced anesthesia, IUGR is surgically created at gestational age day 25 by performing a laparotomy, exposing the bicornuate uterus and then ligating 40-50% of uteroplacental vessels supplying each gestational sac in a single uterine horn. The other horn in the rabbit bicornuate uterus serves as internal control fetuses. Then, after recovery at gestational age day 30 (full term), the same rabbit undergoes examination of fetal cardiac function. Anesthesia is induced with ketamine and xylazine intramuscularly, then maintained by a continuous intravenous infusion of ketamine and xylazine to minimize iatrogenic effects on fetal cardiac function. A repeat laparotomy is performed to expose each gestational sac and a microultrasound examination (VisualSonics VEVO 2100) of fetal cardiac function is performed. Placental insufficiency is evident by a raised pulsatility index or an absent or reversed end diastolic flow of the umbilical artery Doppler waveform. The ductus venosus and middle cerebral artery Doppler is then examined. Fetal echocardiography is performed by recording B mode, M mode and flow velocity waveforms in lateral and apical views. Offline calculations determine standard M-mode cardiac variables, tricuspid and mitral annular plane systolic excursion, speckle tracking and strain analysis, modified myocardial performance index and vascular flow velocity waveforms of interest. This small animal model of IUGR therefore affords examination of in utero
cardiac function that is consistent with current clinical practice and is therefore useful in a translational research setting.
Medicine, Issue 76, Developmental Biology, Biomedical Engineering, Molecular Biology, Anatomy, Physiology, Cardiology, Fetal Therapies, Obstetric Surgical Procedures, Fetal Development, Surgical Procedures, Operative, intrauterine growth restriction, fetal echocardiography, Doppler ultrasound, fetal hemodynamics, animal model, clinical techniques
The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism
Institutions: University of Montréal, McGill University, University of Minnesota.
Transcranial direct current stimulation (tDCS) is a neuromodulation technique that has been increasingly used over the past decade in the treatment of neurological and psychiatric disorders such as stroke and depression. Yet, the mechanisms underlying its ability to modulate brain excitability to improve clinical symptoms remains poorly understood 33
. To help improve this understanding, proton magnetic resonance spectroscopy (1
H-MRS) can be used as it allows the in vivo
quantification of brain metabolites such as γ-aminobutyric acid (GABA) and glutamate in a region-specific manner 41
. In fact, a recent study demonstrated that 1
H-MRS is indeed a powerful means to better understand the effects of tDCS on neurotransmitter concentration 34
. This article aims to describe the complete protocol for combining tDCS (NeuroConn MR compatible stimulator) with 1
H-MRS at 3 T using a MEGA-PRESS sequence. We will describe the impact of a protocol that has shown great promise for the treatment of motor dysfunctions after stroke, which consists of bilateral stimulation of primary motor cortices 27,30,31
. Methodological factors to consider and possible modifications to the protocol are also discussed.
Neuroscience, Issue 93, proton magnetic resonance spectroscopy, transcranial direct current stimulation, primary motor cortex, GABA, glutamate, stroke
Technique and Considerations in the Use of 4x1 Ring High-definition Transcranial Direct Current Stimulation (HD-tDCS)
Institutions: Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Pontifical Catholic University of Ecuador, Charité University Medicine Berlin, The City College of The City University of New York, University of Michigan.
High-definition transcranial direct current stimulation (HD-tDCS) has recently been developed as a noninvasive brain stimulation approach that increases the accuracy of current delivery to the brain by using arrays of smaller "high-definition" electrodes, instead of the larger pad-electrodes of conventional tDCS. Targeting is achieved by energizing electrodes placed in predetermined configurations. One of these is the 4x1-ring configuration. In this approach, a center ring electrode (anode or cathode) overlying the target cortical region is surrounded by four return electrodes, which help circumscribe the area of stimulation. Delivery of 4x1-ring HD-tDCS is capable of inducing significant neurophysiological and clinical effects in both healthy subjects and patients. Furthermore, its tolerability is supported by studies using intensities as high as 2.0 milliamperes for up to twenty minutes.
Even though 4x1 HD-tDCS is simple to perform, correct electrode positioning is important in order to accurately stimulate target cortical regions and exert its neuromodulatory effects. The use of electrodes and hardware that have specifically been tested for HD-tDCS is critical for safety and tolerability. Given that most published studies on 4x1 HD-tDCS have targeted the primary motor cortex (M1), particularly for pain-related outcomes, the purpose of this article is to systematically describe its use for M1 stimulation, as well as the considerations to be taken for safe and effective stimulation. However, the methods outlined here can be adapted for other HD-tDCS configurations and cortical targets.
Medicine, Issue 77, Neurobiology, Neuroscience, Physiology, Anatomy, Biomedical Engineering, Biophysics, Neurophysiology, Nervous System Diseases, Diagnosis, Therapeutics, Anesthesia and Analgesia, Investigative Techniques, Equipment and Supplies, Mental Disorders, Transcranial direct current stimulation, tDCS, High-definition transcranial direct current stimulation, HD-tDCS, Electrical brain stimulation, Transcranial electrical stimulation (tES), Noninvasive Brain Stimulation, Neuromodulation, non-invasive, brain, stimulation, clinical techniques
An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Institutions: University of Washington School of Medicine.
Many women undergo cesarean delivery without problems, however some experience significant pain after cesarean section. Pain is associated with negative short-term and long-term effects on the mother. Prior to women undergoing surgery, can we predict who is at risk for developing significant postoperative pain and potentially prevent or minimize its negative consequences? These are the fundamental questions that a team from the University of Washington, Stanford University, the Catholic University in Brussels, Belgium, Santa Joana Women's Hospital in São Paulo, Brazil, and Rambam Medical Center in Israel is currently evaluating in an international research collaboration. The ultimate goal of this project is to provide optimal pain relief during and after cesarean section by offering individualized anesthetic care to women who appear to be more 'susceptible' to pain after surgery.
A significant number of women experience moderate or severe acute post-partum pain after vaginal and cesarean deliveries. 1
Furthermore, 10-15% of women suffer chronic persistent pain after cesarean section. 2
With constant increase in cesarean rates in the US 3
and the already high rate in Brazil, this is bound to create a significant public health problem. When questioning women's fears and expectations from cesarean section, pain during and after it is their greatest concern. 4
Individual variability in severity of pain after vaginal or operative delivery is influenced by multiple factors including sensitivity to pain, psychological factors, age, and genetics. The unique birth experience leads to unpredictable requirements for analgesics, from 'none at all' to 'very high' doses of pain medication. Pain after cesarean section is an excellent model to study post-operative pain because it is performed on otherwise young and healthy women. Therefore, it is recommended to attenuate the pain during the acute phase because this may lead to chronic pain disorders. The impact of developing persistent pain is immense, since it may impair not only the ability of women to care for their child in the immediate postpartum period, but also their own well being for a long period of time.
In a series of projects, an international research network is currently investigating the effect of pregnancy on pain modulation and ways to predict who will suffer acute severe pain and potentially chronic pain, by using simple pain tests and questionnaires in combination with genetic analysis. A relatively recent approach to investigate pain modulation is via the psychophysical measure of Diffuse Noxious Inhibitory Control (DNIC). This pain-modulating process is the neurophysiological basis for the well-known phenomenon of 'pain inhibits pain' from remote areas of the body. The DNIC paradigm has evolved recently into a clinical tool and simple test and has been shown to be a predictor of post-operative pain.5
Since pregnancy is associated with decreased pain sensitivity and/or enhanced processes of pain modulation, using tests that investigate pain modulation should provide a better understanding of the pathways involved with pregnancy-induced analgesia and may help predict pain outcomes during labor and delivery. For those women delivering by cesarean section, a DNIC test performed prior to surgery along with psychosocial questionnaires and genetic tests should enable one to identify women prone to suffer severe post-cesarean pain and persistent pain. These clinical tests should allow anesthesiologists to offer not only personalized medicine to women with the promise to improve well-being and satisfaction, but also a reduction in the overall cost of perioperative and long term care due to pain and suffering. On a larger scale, these tests that explore pain modulation may become bedside screening tests to predict the development of pain disorders following surgery.
JoVE Medicine, Issue 35, diffuse noxious inhibitory control, DNIC, temporal summation, TS, psychophysical testing, endogenous analgesia, pain modulation, pregnancy-induced analgesia, cesarean section, post-operative pain, prediction
Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles
Institutions: Heart Research Center Goettingen, University Medical Center Goettingen, German Center for Cardiovascular Research (DZHK) partner site Goettingen, University of Maryland School of Medicine.
In cardiac myocytes a complex network of membrane tubules - the transverse-axial tubule system (TATS) - controls deep intracellular signaling functions. While the outer surface membrane and associated TATS membrane components appear to be continuous, there are substantial differences in lipid and protein content. In ventricular myocytes (VMs), certain TATS components are highly abundant contributing to rectilinear tubule networks and regular branching 3D architectures. It is thought that peripheral TATS components propagate action potentials from the cell surface to thousands of remote intracellular sarcoendoplasmic reticulum (SER) membrane contact domains, thereby activating intracellular Ca2+
release units (CRUs). In contrast to VMs, the organization and functional role of TATS membranes in atrial myocytes (AMs) is significantly different and much less understood. Taken together, quantitative structural characterization of TATS membrane networks in healthy and diseased myocytes is an essential prerequisite towards better understanding of functional plasticity and pathophysiological reorganization. Here, we present a strategic combination of protocols for direct quantitative analysis of TATS membrane networks in living VMs and AMs. For this, we accompany primary cell isolations of mouse VMs and/or AMs with critical quality control steps and direct membrane staining protocols for fluorescence imaging of TATS membranes. Using an optimized workflow for confocal or superresolution TATS image processing, binarized and skeletonized data are generated for quantitative analysis of the TATS network and its components. Unlike previously published indirect regional aggregate image analysis strategies, our protocols enable direct characterization of specific components and derive complex physiological properties of TATS membrane networks in living myocytes with high throughput and open access software tools. In summary, the combined protocol strategy can be readily applied for quantitative TATS network studies during physiological myocyte adaptation or disease changes, comparison of different cardiac or skeletal muscle cell types, phenotyping of transgenic models, and pharmacological or therapeutic interventions.
Bioengineering, Issue 92, cardiac myocyte, atria, ventricle, heart, primary cell isolation, fluorescence microscopy, membrane tubule, transverse-axial tubule system, image analysis, image processing, T-tubule, collagenase
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Institutions: University of Arizona, University of Arizona.
A simple, validated protocol consisting of a battery of tests is available to identify elderly patients with frailty syndrome. This syndrome of decreased reserve and resistance to stressors increases in incidence with increasing age. In the elderly, frailty may pursue a step-wise loss of function from non-frail to pre-frail to frail. We studied frailty in HIV-infected patients and found that ~20% are frail using the Fried phenotype using stringent criteria developed for the elderly1,2
. In HIV infection the syndrome occurs at a younger age.
HIV patients were checked for 1) unintentional weight loss; 2) slowness as determined by walking speed; 3) weakness as measured by a grip dynamometer; 4) exhaustion by responses to a depression scale; and 5) low physical activity was determined by assessing kilocalories expended in a week's time. Pre-frailty was present with any two of five criteria and frailty was present if any three of the five criteria were abnormal.
The tests take approximately 10-15 min to complete and they can be performed by medical assistants during routine clinic visits. Test results are scored by referring to standard tables. Understanding which of the five components contribute to frailty in an individual patient can allow the clinician to address relevant underlying problems, many of which are not evident in routine HIV clinic visits.
Medicine, Issue 77, Infection, Virology, Infectious Diseases, Anatomy, Physiology, Molecular Biology, Biomedical Engineering, Retroviridae Infections, Body Weight Changes, Diagnostic Techniques and Procedures, Physical Examination, Muscle Strength, Behavior, Virus Diseases, Pathological Conditions, Signs and Symptoms, Diagnosis, Musculoskeletal and Neural Physiological Phenomena, HIV, HIV-1, AIDS, Frailty, Depression, Weight Loss, Weakness, Slowness, Exhaustion, Aging, clinical techniques
Simultaneous Scalp Electroencephalography (EEG), Electromyography (EMG), and Whole-body Segmental Inertial Recording for Multi-modal Neural Decoding
Institutions: National Institutes of Health, University of Houston, University of Houston, University of Houston, University of Houston.
Recent studies support the involvement of supraspinal networks in control of bipedal human walking. Part of this evidence encompasses studies, including our previous work, demonstrating that gait kinematics and limb coordination during treadmill walking can be inferred from the scalp electroencephalogram (EEG) with reasonably high decoding accuracies. These results provide impetus for development of non-invasive brain-machine-interface (BMI) systems for use in restoration and/or augmentation of gait- a primary goal of rehabilitation research. To date, studies examining EEG decoding of activity during gait have been limited to treadmill walking in a controlled environment. However, to be practically viable a BMI system must be applicable for use in everyday locomotor tasks such as over ground walking and turning. Here, we present a novel protocol for non-invasive collection of brain activity (EEG), muscle activity (electromyography (EMG)), and whole-body kinematic data (head, torso, and limb trajectories) during both treadmill and over ground walking tasks. By collecting these data in the uncontrolled environment insight can be gained regarding the feasibility of decoding unconstrained gait and surface EMG from scalp EEG.
Behavior, Issue 77, Neuroscience, Neurobiology, Medicine, Anatomy, Physiology, Biomedical Engineering, Molecular Biology, Electroencephalography, EEG, Electromyography, EMG, electroencephalograph, gait, brain-computer interface, brain machine interface, neural decoding, over-ground walking, robotic gait, brain, imaging, clinical techniques
Oscillation and Reaction Board Techniques for Estimating Inertial Properties of a Below-knee Prosthesis
Institutions: University of Northern Colorado, Arizona State University, Iowa State University.
The purpose of this study was two-fold: 1) demonstrate a technique that can be used to directly estimate the inertial properties of a below-knee prosthesis, and 2) contrast the effects of the proposed technique and that of using intact limb inertial properties on joint kinetic estimates during walking in unilateral, transtibial amputees. An oscillation and reaction board system was validated and shown to be reliable when measuring inertial properties of known geometrical solids. When direct measurements of inertial properties of the prosthesis were used in inverse dynamics modeling of the lower extremity compared with inertial estimates based on an intact shank and foot, joint kinetics at the hip and knee were significantly lower during the swing phase of walking. Differences in joint kinetics during stance, however, were smaller than those observed during swing. Therefore, researchers focusing on the swing phase of walking should consider the impact of prosthesis inertia property estimates on study outcomes. For stance, either one of the two inertial models investigated in our study would likely lead to similar outcomes with an inverse dynamics assessment.
Bioengineering, Issue 87, prosthesis inertia, amputee locomotion, below-knee prosthesis, transtibial amputee
A Proboscis Extension Response Protocol for Investigating Behavioral Plasticity in Insects: Application to Basic, Biomedical, and Agricultural Research
Institutions: Arizona State University.
Insects modify their responses to stimuli through experience of associating those stimuli with events important for survival (e.g.
, food, mates, threats). There are several behavioral mechanisms through which an insect learns salient associations and relates them to these events. It is important to understand this behavioral plasticity for programs aimed toward assisting insects that are beneficial for agriculture. This understanding can also be used for discovering solutions to biomedical and agricultural problems created by insects that act as disease vectors and pests. The Proboscis Extension Response (PER) conditioning protocol was developed for honey bees (Apis mellifera
) over 50 years ago to study how they perceive and learn about floral odors, which signal the nectar and pollen resources a colony needs for survival. The PER procedure provides a robust and easy-to-employ framework for studying several different ecologically relevant mechanisms of behavioral plasticity. It is easily adaptable for use with several other insect species and other behavioral reflexes. These protocols can be readily employed in conjunction with various means for monitoring neural activity in the CNS via electrophysiology or bioimaging, or for manipulating targeted neuromodulatory pathways. It is a robust assay for rapidly detecting sub-lethal effects on behavior caused by environmental stressors, toxins or pesticides.
We show how the PER protocol is straightforward to implement using two procedures. One is suitable as a laboratory exercise for students or for quick assays of the effect of an experimental treatment. The other provides more thorough control of variables, which is important for studies of behavioral conditioning. We show how several measures for the behavioral response ranging from binary yes/no to more continuous variable like latency and duration of proboscis extension can be used to test hypotheses. And, we discuss some pitfalls that researchers commonly encounter when they use the procedure for the first time.
Neuroscience, Issue 91, PER, conditioning, honey bee, olfaction, olfactory processing, learning, memory, toxin assay
A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
Institutions: Concordia University.
Environmental contexts in which drugs of abuse are consumed can trigger craving, a subjective Pavlovian-conditioned response that can facilitate drug-seeking behavior and prompt relapse in abstinent drug users. We have developed a procedure to study the behavioral and neural processes that mediate the impact of context on alcohol-seeking behavior in rats. Following acclimation to the taste and pharmacological effects of 15% ethanol in the home cage, male Long-Evans rats receive Pavlovian discrimination training (PDT) in conditioning chambers. In each daily (Mon-Fri) PDT session, 16 trials each of two different 10 sec auditory conditioned stimuli occur. During one stimulus, the CS+, 0.2 ml of 15% ethanol is delivered into a fluid port for oral consumption. The second stimulus, the CS-, is not paired with ethanol. Across sessions, entries into the fluid port during the CS+ increase, whereas entries during the CS- stabilize at a lower level, indicating that a predictive association between the CS+ and ethanol is acquired. During PDT each chamber is equipped with a specific configuration of visual, olfactory and tactile contextual stimuli. Following PDT, extinction training is conducted in the same chamber that is now equipped with a different configuration of contextual stimuli. The CS+ and CS- are presented as before, but ethanol is withheld, which causes a gradual decline in port entries during the CS+. At test, rats are placed back into the PDT context and presented with the CS+ and CS- as before, but without ethanol. This manipulation triggers a robust and selective increase in the number of port entries made during the alcohol predictive CS+, with no change in responding during the CS-. This effect, referred to as context-induced renewal, illustrates the powerful capacity of contexts associated with alcohol consumption to stimulate alcohol-seeking behavior in response to Pavlovian alcohol cues.
Behavior, Issue 91, Behavioral neuroscience, alcoholism, relapse, addiction, Pavlovian conditioning, ethanol, reinstatement, discrimination, conditioned approach
Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
Institutions: University of Zurich.
Mori's Uncanny Valley Hypothesis1,2
proposes that the perception of humanlike characters such as robots and, by extension, avatars (computer-generated characters) can evoke negative or positive affect (valence) depending on the object's degree of visual and behavioral realism along a dimension of human likeness
) (Figure 1
). But studies of affective valence of subjective responses to variously realistic non-human characters have produced inconsistent findings 3, 4, 5, 6
. One of a number of reasons for this is that human likeness is not perceived as the hypothesis assumes. While the DHL can be defined following Mori's description as a smooth linear change in the degree of physical humanlike similarity, subjective perception of objects along the DHL can be understood in terms of the psychological effects of categorical perception (CP) 7
. Further behavioral and neuroimaging investigations of category processing and CP along the DHL and of the potential influence of the dimension's underlying category structure on affective experience are needed. This protocol therefore focuses on the DHL and allows examination of CP. Based on the protocol presented in the video as an example, issues surrounding the methodology in the protocol and the use in "uncanny" research of stimuli drawn from morph continua to represent the DHL are discussed in the article that accompanies the video. The use of neuroimaging and morph stimuli to represent the DHL in order to disentangle brain regions neurally responsive to physical human-like similarity from those responsive to category change and category processing is briefly illustrated.
Behavior, Issue 76, Neuroscience, Neurobiology, Molecular Biology, Psychology, Neuropsychology, uncanny valley, functional magnetic resonance imaging, fMRI, categorical perception, virtual reality, avatar, human likeness, Mori, uncanny valley hypothesis, perception, magnetic resonance imaging, MRI, imaging, clinical techniques
Contextual and Cued Fear Conditioning Test Using a Video Analyzing System in Mice
Institutions: Fujita Health University, Core Research for Evolutionary Science and Technology (CREST), National Institutes of Natural Sciences.
The contextual and cued fear conditioning test is one of the behavioral tests that assesses the ability of mice to learn and remember an association between environmental cues and aversive experiences. In this test, mice are placed into a conditioning chamber and are given parings of a conditioned stimulus (an auditory cue) and an aversive unconditioned stimulus (an electric footshock). After a delay time, the mice are exposed to the same conditioning chamber and a differently shaped chamber with presentation of the auditory cue. Freezing behavior during the test is measured as an index of fear memory. To analyze the behavior automatically, we have developed a video analyzing system using the ImageFZ application software program, which is available as a free download at http://www.mouse-phenotype.org/. Here, to show the details of our protocol, we demonstrate our procedure for the contextual and cued fear conditioning test in C57BL/6J mice using the ImageFZ system. In addition, we validated our protocol and the video analyzing system performance by comparing freezing time measured by the ImageFZ system or a photobeam-based computer measurement system with that scored by a human observer. As shown in our representative results, the data obtained by ImageFZ were similar to those analyzed by a human observer, indicating that the behavioral analysis using the ImageFZ system is highly reliable. The present movie article provides detailed information regarding the test procedures and will promote understanding of the experimental situation.
Behavior, Issue 85, Fear, Learning, Memory, ImageFZ program, Mouse, contextual fear, cued fear
In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
Institutions: Pacific Northwest National Laboratory.
Soft landing of mass-selected ions onto surfaces is a powerful approach for the highly-controlled preparation of materials that are inaccessible using conventional synthesis techniques. Coupling soft landing with in situ
characterization using secondary ion mass spectrometry (SIMS) and infrared reflection absorption spectroscopy (IRRAS) enables analysis of well-defined surfaces under clean vacuum conditions. The capabilities of three soft-landing instruments constructed in our laboratory are illustrated for the representative system of surface-bound organometallics prepared by soft landing of mass-selected ruthenium tris(bipyridine) dications, [Ru(bpy)3
(bpy = bipyridine), onto carboxylic acid terminated self-assembled monolayer surfaces on gold (COOH-SAMs). In situ
time-of-flight (TOF)-SIMS provides insight into the reactivity of the soft-landed ions. In addition, the kinetics of charge reduction, neutralization and desorption occurring on the COOH-SAM both during and after ion soft landing are studied using in situ
Fourier transform ion cyclotron resonance (FT-ICR)-SIMS measurements. In situ
IRRAS experiments provide insight into how the structure of organic ligands surrounding metal centers is perturbed through immobilization of organometallic ions on COOH-SAM surfaces by soft landing. Collectively, the three instruments provide complementary information about the chemical composition, reactivity and structure of well-defined species supported on surfaces.
Chemistry, Issue 88, soft landing, mass selected ions, electrospray, secondary ion mass spectrometry, infrared spectroscopy, organometallic, catalysis
Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
Institutions: Stanford University School of Medicine .
We describe a methodology by which we are able to collect and measure biochemical inflammatory and nociceptive mediators at the surgical wound site. Collecting site-specific biochemical markers is important to understand the relationship between levels in serum and surgical wound, determine any associations between mediator release, pain, analgesic use and other outcomes of interest, and evaluate the effect of systemic and peripheral drug administration on surgical wound biochemistry. This methodology has been applied to healthy women undergoing elective cesarean delivery with spinal anesthesia. We have measured wound exudate and serum mediators at the same time intervals as patient's pain scores and analgesics consumption for up to 48 hours post-cesarean delivery. Using this methodology we have been able to detect various biochemical mediators including nerve growth factor (NGF), prostaglandin E2 (PG-E2) substance P, IL-1β, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-17, TNFα, INFγ, G-CSF, GM-CSF, MCP-1 and MIP-1β. Studies applying this human surgical wound bioassay have found no correlations between wound and serum cytokine concentrations or their time-release profile (J Pain. 2008; 9(7):650-7).1
We also documented the utility of the technique to identify drug-mediated changes in wound cytokine content (Anesth Analg 2010; 111:1452-9).2
Medicine, Issue 68, Biochemistry, Anatomy, Physiology, Cytokines, Cesarean Section, Wound Healing, Wounds and Injuries, Surgical Procedures, Operative, Surgical wound, Exudate, cytokines, Substance P, Interleukin 10, Interleukin 6, Nerve growth factor, Prostaglandin E2, Cesarean, Analgesia
Ex Vivo Culture of Patient Tissue & Examination of Gene Delivery
Institutions: University College Cork, University College Cork.
This video describes the use of patient tissue as an ex vivo
model for the study of gene delivery. Fresh patient tissue obtained at the time of surgery is sliced and maintained in culture. The ex vivo
model system allows for the physical delivery of genes into intact patient tissue and gene expression is analysed by bioluminescence imaging using the IVIS detection system. The bioluminescent detection system demonstrates rapid and accurate quantification of gene expression within individual slices without the need for tissue sacrifice. This slice tissue culture system may be used in a variety of tissue types including normal and malignant tissue and allows us to study the effects of the heterogeneous nature of intact tissue and the high degree of variability between individual patients. This model system could be used in certain situations as an alternative to animal models and as a complementary preclinical mode prior to entering clinical trial.
Medicine, Issue 46, Bioluminescent imaging, Ex vivo tissue model, Preclinical research, Gene delivery
Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
Institutions: Aleris-Hamlet Hospitals, Soeborg, Denmark, Aleris-Hamlet Hospitals, Soeborg, Denmark.
Shoulder pain is a commonly reported symptom following laparoscopic procedures such as myomectomy or hysterectomy, and recent studies have shown that lowering the insufflation pressure during surgery may reduce the risk of post-operative pain. In this pilot study, a method is presented for measuring the intra-abdominal space available to the surgeon during laproscopy, in order to examine whether the relaxation produced by deep neuromuscular blockade can increase the working surgical space sufficiently to permit a reduction in the CO2
insufflation pressure. Using the laproscopic grasper, the distance from the promontory to the skin is measured at two different insufflation pressures: 8 mm Hg and 12 mm Hg. After the initial measurements, a neuromuscular blocking agent (rocuronium) is administered to the patient and the intra-abdominal volume is measured again. Pilot data collected from 15 patients shows that the intra-abdominal space at 8 mm Hg with blockade is comparable to the intra-abdominal space measured at 12 mm Hg without blockade. The impact of neuromuscular blockade was not correlated with patient height, weight, BMI, and age. Thus, using neuromuscular blockade to maintain a steady volume while reducing insufflation pressure may produce improved patient outcomes.
Medicine, Issue 76, Anatomy, Physiology, Neurobiology, Surgery, gynecology, laparoscopy, deep neuromuscular blockade, reversal, rocuronium, sugammadex, laparoscopic surgery, clinical techniques, surgical techniques | <urn:uuid:06d54a25-cc7d-482a-b233-c25b7d86526f> | CC-MAIN-2017-04 | http://www.jove.com/visualize/abstract/24586295/mode-delivery-offspring-body-mass-index-overweight-obesity-adult-life | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560283008.19/warc/CC-MAIN-20170116095123-00081-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.898518 | 10,108 | 2.671875 | 3 |
Giovanni Battista Beinaschi, Martyrdom of Saint Peter. Oil on canvas, 290 x 193cm; 114.25 x 76 inches.
NEW YORK, NY.- A major exhibition of Italian paintings will open at the 22 East 80th Street gallery of Otto Naumann Ltd. on January 6 and remain on view until February 15.
“Looking South: Three Centuries of Italian Paintings” will feature more than forty Renaissance and Baroque masterworks dating from the sixteenth to the eighteenth centuries, including several important discoveries never before publicly exhibited.
According to Otto Naumann, “The rich history of the collecting of Italian Renaissance and Baroque painting in America has been explored in several recent books and exhibitions. This past September the Frick Collection sponsored a two-day conference “Going for Baroque; Americans Collect Italian Paintings of the 17th and 18th Centuries.” It was at this event that the idea for “Looking South” was born.”
Attending the conference were Otto Naumann and Robert Simon, both Old Master painting dealers with a passion for Italy and Italian art who began their careers as art historians. During the lunch break they lamented the fact that there had been no major commercial exhibition of Italian paintings in New York for many years – this despite a resurgent interest among collectors and museums for paintings of the period. They decided to combine their resources and expertise in order to mount “Looking South.”
The exhibited works range from portraits to still-lifes, from mythological subjects to mysterious allegories, from intimate devotional paintings to grand altarpieces. Paintings by some of the greatest names of Italian art will be featured, including Titian, Palma Vecchio, Ribera, Baglione, Crespi, Cavallino, Mattia Preti, Ceruti, and Bellotto. These have all been carefully conserved and meticulously researched, a process that draws on the academic backgrounds of the two organizers as well as their decades of experience in the connoisseurship of Old Master paintings.
Otto Naumann received his M.A. from Columbia in 1974 and his Ph.D. from Yale in 1979 and was a Professor of Art History at Boston University and the University of Delaware before leaving academe. His catalogue of the paintings of Frans van Mieris is the standard work on the artist; as a dealer he has handled works by Rembrandt, Vermeer, Hals, Rubens and Velazquez.
Robert Simon’s 1982 doctorate is from Columbia. He was a Research Fellow at the Metropolitan Museum and has published and lectured widely on Bronzino, the subject of his thesis, and numerous aspects of Italian painting. He was involved in the recent discovery of Leonardo da Vinci’s lost painting Salvator Mundi and is currently writing a book about its history and recovery.
All works in the exhibition are for sale. A brochure and digital catalogue will be available on January 6 at www.ottonaumannltd.com or www.robertsimon.com. Otto Naumann Ltd is located at 22 East 80th Street. Exhibition hours are from Monday to Saturday, 11 to 5.
Among highlights in the exhibition will be a major painting by Titian, “St. Sebastian,” painted for his patron Federico Gonzaga, oil on canvas 74 ¾ by 37 ¾ inches, Giovanni Battista Beinaschi’s altarpiece the “Martyrdom of Saint Peter,” oil on canvas 116 ¼ x 76 inches, Bernardo Bellotto’s “Architectural Caprice with Self-portrait,” oil on canvas 61 ½ x 44 ¼ inches, and a spectacular “Still-Life with Musical Instrument” by Evaristo Baschenis, oil on canvas 38 x 57 1/7 inches.
Bernardo Bellotto (Venice 1721 – 1780 Warsaw), Architectural Capriccio with a Self-Portrait of Bellotto in the Costume of a Venetian Nobleman, oil on canvas, 60 ½ x 44 ¼ inches (155 x 112 cm.)
inscribed on the pillar, right: …/LENF/…/PROD…/DE M. VO…/SUIV…/PICTORIBUS/ATQUE POETIS/QUIDLIBET AUDENDI/SEMPER FUIT/AEQUA POTESTAS/.E ART. POETICA LI…
Provenance: Count Alessandro Contini-Buonacossi, Florence;
Eugene Victor Thaw and Stanley Moss and Co., New York, March 1976;
Collection of Walter P. Chrysler, Jr., New York;
His sale, Sotheby’s, New York, 1 June 1989, lot 84;
Private Collection, London.
Exhibited: Probably Dresden, Academy, 1765;
On loan to the Chrysler Museum at Norfolk, March 1976;
Nashville, 1977, no. 23.
Literature: Stefan Kozakiewicz, Bernardo Bellotto, 1972, vol. 1, p. 139, vol. II, p. 265, no. 334a, illus. p. 271;
Ettore Camesasca, L’Opera Completa del Bellotto, 1974, p. 194, no. 194;
Eric Zafran, “From the Renaissance to the Grand Tour,” Apollo, April 1978, pp. 250-1, fig. 14;
George T.M. Shackelford et al., A Gift to America: Masterpieces of European Painting from the Samuel H. Kress Collection, exhibition catalogue Raleigh (North Carolina Museum of Art), Houston (Museum of Fine Arts), Seattle (Seattle Art Museum), San Francisco (Fine Arts Museum of San Francisco), 1995, p. 230.
Evaristo Baschenis (1617 – Bergamo – 1677), A still life with musical instruments, signed on the edge of the spinet: EVARISTUS BASCHENIS P., oil on canvas,38 x 57 ⅛ inches (98 x 145 cm.).
Provenance: Count Moroni, Bergamo;
sale, Christie’s, New York, 6 April 2006, lot 60.
Literature: G. de Logu, Pittori minori Liguri, Lombardi, Piemontese del seicento e del settocento, Venice, 1931, p. 220;
L. Angelini, I Baschenis, Bergamo, 1946, p. 85, plate XLII;
M. Rosci, Baschenis, Bettera & Co. Produzinoe e Mercato della natura morta de seicento in Italia, Milan, 1971, pp. 50-1, 55 and 124, no. 103, illustrated;
J.T. Spike, Italian still life paintings from three centuries, exhibition catalogue, Florence, 1984, pp. 76-7, no. 24;
L. Salerno, Italian still life paintings from three centuries, The Silvano Lodi collection, exhibition catalogue, Florence, 1984, pp. 94-5, no. 39. illustrated;
L. Salerno, Italian still life painting in Italy, 1560 – 1805, Rome, 1984, p. 155, fig. 39.2;
L. Ravelli, Bartolomeno Arbotoni piacentino, maestro di Evaristo Baschenis: ipotesti sulla formazione del picttore bergamasco, Bergamo, 1987, p. 51. no. 46;
G. Anedi, et al., La curiosità dipinta:elementi di collezionismo tra XVI et XVIII secolo, exhibition catalogue, Milan, 1990, p. 35, no. III;
C. Bertelli, et al., Evaristo Baschenis e la natura morta in Europa, exhibition catalogue, Milan, 1996, pp. 184-7, no. 24;
A. Bayer, ed., The Still Lifes of Evaristo Baschenis – The Music of Silence, exhibition catalogue, The Metropolitan Museum of Art, Milan, 2000, p. 37, fig. 19, detail ill., pp. 43 and 51;
S. Dathe, Natura morte italiana: Italienisches stilleben aus vier Jahrhunderten, Sammlung Silvano Lodi, exhibition catalogue, Ravensburg, 2003.
Exhibited: National Academy of Design, New York, Italian still life paintings from three centuries, 2 February – 13 March 1983, no. 24; Philbrook Art center, Tulsa, 9 April – 30 June 1983;
Dayton Art Institute, Dayton, Ohio, 30 July – 11 September, 1983.
Bayerische Staatsgemäldesammlungen, Alte Pinokothek, Munich, Italian still life painting from three centuries, The Silvano Lodi collection, 27 November 1984 – 22 February 1985, no. 37; Gemäldegalerie Staatliche Museen-Pressicher Kulturbesitz, Berlin, 6 September – 27 October 1985;
X Internationale Antiquariato, Milan, La curiosità dipinta: elementi di collectionismo tra XVI et XVIII secolo, 30 March – 8 April 1990, no. III; Galleria Principe Eugenio, Turin, 18 April – 5 May 1990;
Israel Museum, Jerusalem, Italian still life painting, The Silvano Lodi collection, June 1994;
Galleria d’arte moderna e contemporanea, Bergamo, Evaristo Baschenis e la natura morta in Europa, 4 October 1996 – 12 January 1997, no. 24;
Seijo Togo Memorial Kasai Museum of Art, Tokyo, Italian still life painting, from The Silvano Lodi collection, 28 April – 26 May 2001, no. 25;
Schloss Achberg, Ravensburg, Natura morte Italian: Italiensche stilleben aus vier Jahrhunderten, Sammlung Silvano Lodi, 11 April – 12 October 2003;
On loan to the Metropolitan Museum of Art, New York, 24 April 2008 – 24 September 2009. | <urn:uuid:3fe2c399-9253-4a92-91f4-7c31357b2aae> | CC-MAIN-2017-04 | http://www.alaintruong.com/archives/2013/12/30/28796404.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560285315.77/warc/CC-MAIN-20170116095125-00566-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.871818 | 2,205 | 1.875 | 2 |
Monday, November 21, 2005
Question from Camille - Elizabeth I, Mary I and Mary QOS' tombs
I visited Westminister Abbey several years ago and was absolutely astonded at the placement of the tomb of Elizebeth I being in a crowded area compared to where and how the tomb of Mary Stuart's was placed.!! Also it seems that James gave his mother's tomb more precedence then Elizebeth who placed him on the thrown. Also, why were Elizebeth & Mary placed in the same tomb when they disliked each other? It seems like a joke played on them by James. The docet at the Abbey couldn't give me an answer except to say that James had it done after Mary's tomb collapsed....is that true? It just seems that Elizebeth deserved better. | <urn:uuid:e9e8395d-3b38-411c-a28a-3cfcf9cfeae4> | CC-MAIN-2022-33 | https://queryblog.tudorhistory.org/2005/11/question-from-camille-elizabeth-i-mary.html?m=0 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571987.60/warc/CC-MAIN-20220813202507-20220813232507-00278.warc.gz | en | 0.990211 | 169 | 1.96875 | 2 |
Top Benefits of Semi-Automation for Materials Testing
Companies look towards automation to implement certain improvements in their business, including cost reduction and a safer and more efficient work environment. Automation can be implemented in many processes, from the production line to test labs. Fully automated materials testing systems are available to test hundreds of specimens without operator interference, even running overnight. These systems, however, aren’t necessarily the right solution for all test labs. Many labs don’t have the testing volume to make a reasonable return on investment of a fully automated system. Or instead of testing material coupons typical of an automated system, they may be performing component testing. For those customers, a semi-automated testing system may be a more suitable option for both their application and budget.
The addition of a semi-automated XY stage to a testing system brings several benefits to the lab:
- Increased throughput reduces the overall test time
- Greater efficiency allows operators to make better use of their time
- Increased repeatability results from more consistent test set up
- Increased safety and ergonomics for operators
Throughput is one of the most important metrics in a test lab. The data generated by the lab is important to the overall success of the company; the results may be used in product development projects or to check product quality as it comes off the production line. Delays in testing may impact critical company targets, such as time-to-market for a new product or shipment deadlines.
The amount of time it takes to complete an actual test is fixed, whether the system is automated or manual. Test time is often regulated by international standards such as ISO, ASTM, and EN standards, or by company test procedures. The part of the process that can significantly increase the overall test time are the actions that occur between each test. The tested specimen must first be removed, making sure no remnants are left behind. Then the operator has to carefully set up the next specimen, making sure it is properly positioned and aligned. This takes time, which can vary greatly depending on the complexity of the test and the user’s experience. These are the areas – the time between tests - where a semi-automated system can greatly contribute to lab throughput.
One example of how an XY stage can benefit throughput is to look at data from benchmark testing that was performed on springs used in a surgical tool. Fifty specimens were run manually, which took nearly 16 minutes. The operator ran the tests one immediately after another, with no breaks or distractions. In reality, an operator who is manually running tests has regular interruptions, such as meetings, breaks, or conversations with colleagues, where testing is paused.
Those same fifty tests run using the semi-automated XY system took about 8.5 minutes. The XY system made it possible to test 46% more specimens in the same amount of time. This extra time may make the difference when it comes to time-to-market, hitting engineering project milestones, or releasing a product for shipment.
Customers using an XY system can maximize throughput even further by having multiple test fixtures available. While one batch of specimens is undergoing testing, the operator can prepare the next batch by setting all the specimens to be tested into the fixture. This minimizes downtime between tests, as the operator can quickly set up a new sample on the XY system and press start. Testing backlogs can be worked through more quickly, providing faster turnaround on data that is needed for R&D projects and on production lines.
While the XY stage helps increase lab throughput, it simultaneously improves efficiency by freeing up a significant amount of the operator’s time. The use of automation means the operator no longer needs to stand by the system while tests are run. They are free to walk away from the system and perform other value-added tasks, such as data analysis, completion of test reports, or measuring and preparing the next batch of specimens for testing.
The benchmark data from the spring tests shows that, in addition to increasing lab throughput by 46% over the course of an 8 hour shift, the operator will gain 3.5 hours of time back that would otherwise be spent in front of the system manually running tests. This 3.5 hours is time that can be used more efficiently.
There are many factors that impact repeatability. Specimen placement is important: if the specimen is not centered properly or is at an angle compared with the loading line, this will introduce variation into the results. While there are tools available to help with proper specimen alignment, this still relies on operator experience, and time and care still must be taken to set up a specimen. The XY stage is able to position test components or specimens with greater repeatability.
The operator’s influence on test results when specimens are inserted and aligned manually can be especially noticeable when you have multiple operators, with varying levels of experience, running tests on multiple systems or even across multiple labs. This is compounded when testing multiple points on small components. The integrated chips shown in the photo above are very small. Ensuring that these parts are tested in the center and at the same 4 points around the edge is challenging when setting the specimens up manually. An XY system with a well-designed fixture addresses the challenges around specimen placement and consistency of test locations. An XY stage provides repeatable test locations from sample to sample, ensuring that the data being generated is comparable.
OSHA estimates that companies in the U.S. pay $1 billion in direct worker compensation per week. This doesn’t include other costs related to disruptions to the lab. If an operator is out on medical leave, the lab’s throughput will likely be lower due to reduced staff. If the injured operator is the only one with knowledge on how to run a particular system or test, that loss of expertise will affect the lab’s ability to meet their customers’ requirements. Also, accidents in the lab often negatively impact user confidence when operating the equipment.
The reduced need for operator interaction when using an XY system results in increased safety, as the operator’s hands are rarely in the test space. It also offers better ergonomics as it removes the repetitive motion that is required when manually loading specimens.
Because the XY system removes some of the testing challenges around specimen alignment and test points, operators with less experience can be trained more quickly, will find the system easier to use, and will be more confident running the system. This lessens disruption in the lab.
Semi-automated systems such as the XY stage, can provide many benefits – throughput, efficiency, repeatability, and safety – to labs where a fully automated system isn't the best fit. The XY stage allows testing labs to implement automation on a smaller scale that is well suited for a range of applications, including medical devices, such as vials and syringes, and electronic devices and components. | <urn:uuid:7f72736a-b16e-4b4e-8a0c-5b185cb8419f> | CC-MAIN-2022-33 | https://www.instron.com/en-gb/resources/blog/2022/june/top-benefits-of-semi-automation-for-materials-testing?region=United%20Kingdom | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571911.5/warc/CC-MAIN-20220813081639-20220813111639-00469.warc.gz | en | 0.949728 | 1,420 | 2.21875 | 2 |
Individual differences |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |
Biological: Behavioural genetics · Evolutionary psychology · Neuroanatomy · Neurochemistry · Neuroendocrinology · Neuroscience · Psychoneuroimmunology · Physiological Psychology · Psychopharmacology (Index, Outline)
Genetics studies how living organisms inherit many of the features of their ancestors – for example, children usually look and act like other people in their family. Genetics tries to identify which features are inherited, and work out the details of how these features are passed from generation to generation.
In genetics, a feature of an organism is called a "trait". Some traits are features of an organism's physical appearance, for example, a person's eye color, height or weight. There are many other types of traits and these range from aspects of behavior to resistance to disease. Traits are often inherited, for example tall and thin people tend to have tall and thin children. Other traits come from the interaction between inherited features and the environment. For example a child might inherit the tendency to be tall, but if there is very little food where they live and they are poorly nourished, they will still be short. The way genetics and environment interact to produce a trait can be complicated: for example, the chances of somebody dying of cancer or heart disease seem to depend on both their family history and their lifestyle.
Genetic information is carried by a long molecule called DNA and this DNA is copied and inherited across generations. Traits are carried in DNA as instructions for constructing and operating an organism. These instructions are contained in segments of DNA called genes. DNA is made of a sequence of simple units, with the order of these units spelling out instructions in the genetic code. This is similar to the orders of letters spelling out words. The organism "reads" the sequence of these units and decodes the instruction.
Not all the genes for a particular instruction are exactly the same. Different forms of one type of gene are called different alleles of that gene. As an example, one allele of a gene for hair color could carry the instruction to produce a lot of the pigment in black hair, while a different allele could give a garbled version of this instruction, so that no pigment is produced and the hair is white. Mutations are random events that change the sequence of a gene and therefore create a new allele. Mutations can produce a new trait, such as turning an allele for black hair into an allele for white hair. The appearance of new traits is important in evolution.
Inheritance in biologyEdit
Genes and inheritanceEdit
Genes are inherited as units, with parents dividing out their genes to their offspring. You can think of this process like mixing two hands of cards, shuffling them, and then dealing them out again. Humans have two copies of each of their genes and when people reproduce they make copies of their genes in eggs or sperm, but only put in one copy of each type of gene. An egg then joins with a sperm to give a child with a new set of genes. This child will have the same number of genes as its parents but for any gene one of their two copies will come from the father, and one from the mother.
The effects of this mixing depends on the types (the alleles) of the gene you are interested in. If the father has two alleles specifying green eyes, and the mother has two alleles specifying brown eyes, all their children will get two alleles giving different instructions, one for green eyes and one for brown. The eye color of these children depends on how these alleles work together. If one allele overrides the instructions from another, it is called the dominant allele, and the allele that is overridden is called the recessive allele. In the case of a daughter with both green and brown alleles, brown is dominant and she ends up with brown eyes.
However, the green eye color allele is still there in this brown-eyed girl, it just doesn't show. This is a difference between what you see on the surface (the set of observable traits of an organism, also called its phenotype) and which genes are in this organism (its genotype). In this example you can call the brown allele "B" and the green allele "g". (It is normal to write dominant alleles with capital letters and recessive ones with lower-case letters.) The brown-eyed daughter has the "brown eye phenotype" but her genotype is Bg, with one copy of the B allele, and one of the g allele.
Now imagine that this woman grows up and has children with a brown-eyed man who also has a Bg genotype. Her eggs will be a mixture of two types, one sort containing the B allele, and one sort the g allele. Similarly, her partner will produce a mix of two types of sperm containing one or the other of the two alleles. Now, when the alleles are mixed up in the offspring, these children have a chance of getting either brown or green eyes, since they could get a genotype of BB = brown eyes, Bg = brown eyes or gg = green eyes. In this generation, there is therefore a chance of the recessive allele showing itself in the phenotype of the children - some of them may have green eyes like their grandfather.
Many traits are inherited in a more complicated way than the example above. This can happen when there are several genes involved, each contributing a small part to the end result. Tall people tend to have tall children because their children get a package of many alleles that each contribute a bit to how much they grow. However, there are not clear groups of "short people" and "tall people", like there are groups of people with brown or green eyes. This is because of the large number of genes involved; this makes the trait very variable and people are many different heights. Inheritance can also be complicated when the trait depends on the interaction between genetics and the environment. This is quite common, for example, if a child does not eat enough nutritious food this will not change traits like eye color, but it could stunt their growth.
Some diseases are hereditary and run in families; others, such as infectious diseases, are caused by the environment. Other disorders are caused by a combination of hereditary and environmental factors.
Diseases that are caused by a single allele of a gene and are inherited in families are called genetic disorders. These include diseases like Huntington's disease, Cystic fibrosis or Duchenne muscular dystrophy. Cystic fibrosis, for example, is caused by mutations in a single gene called CFTR and is inherited as a recessive trait. Other diseases are influenced by genetics, but which alleles a person gets from their parents only changes their risk of getting a disease. Most of these diseases are inherited in a complex way, with either multiple genes involved, or both genes and the environment being important.
As an example, the risk of breast cancer is 50 times higher in the families most at risk, compared to the families least at risk. This variation is probably due to a large number of alleles. Each of them changes the risk a little bit. Several of the genes involved have been identified, such as BRCA1 and BRCA2, but not all of them. However, although some of the risk is genetic, being overweight, drinking a lot of alcohol, or not exercising, all increase the risk of this cancer. A woman's risk of breast cancer is therefore the result of a large number of alleles and her environment, so it is very hard to predict.
How genes workEdit
Genes make proteinsEdit
The function of genes is to provide the information needed to make molecules called proteins in cells. Cells are the smallest independent parts of organisms: the human body contains about 100 trillion cells, while very small organisms like bacteria are just a single cell. A cell is like a miniature and very complex factory that can make all the parts needed to produce a copy of itself, which happens when cells divide. There is a simple division of labor in cells - genes give instructions and proteins carry out these instructions, tasks like building a new copy of a cell, or repairing damage. Each type of protein is a specialist that only does one job, so if a cell needs to do something new, it must make a new protein to do this job. Similarly, if a cell needs to do something faster or slower than before, it makes more or less of the protein responsible. Genes tell cells what to do by telling them which proteins to make and in what amounts.
Proteins are made of a chain of 20 different types of amino acids. This chain folds up into a compact shape, rather like an untidy ball of rope. The shape of the protein is determined by the sequence of amino acids along its chain and it is this shape that, in turn, determines what the protein will do. For example, some proteins have depressions in their surface that perfectly match another molecule, allowing the protein to bind to this molecule very tightly. Other proteins are enzymes, which are like tiny machines that can alter other molecules.
In DNA information is held in the sequence of the repeating units along the DNA chain. These units are four types of nucleotides (A,T,G and C) and the sequence of nucleotides stores information in an alphabet called the genetic code. When a gene is read by a cell the DNA sequence is copied into a very similar molecule called RNA (this process is called transcription). Transcription is controlled by other DNA sequences (such as promoters), which show a cell where genes are, and control how often they are copied. The RNA copy made from a gene is then fed through a structure called a ribosome, which translates the sequence of nucleotides in the RNA into the correct sequence of amino acids and joins these amino acids together to make a complete protein chain. The new protein then folds up into its active form. The process of moving information from the language of DNA into the language of amino acids is called translation.
If the sequence of the nucleotides in a gene changes, the sequence of the amino acids in the protein it produces may also change - if part of a gene is deleted, the protein produced will be shorter and may not work any more. This is the reason why different alleles of a gene can have different effects in an organism. As an example, hair color depends on how much of a dark substance called melanin is put into the hair as it grows. If a person has a normal set of the genes involved in making melanin, they make all the proteins needed and they grow dark hair. However, if the alleles for a particular protein have different sequences and produce proteins that do not do the job correctly, no melanin will be produced and the hair will be white. This condition is called albinism and the person suffering from it is called an albino.
Copies of genes are inheritedEdit
When genes are passed from a parent to a child they are copied - the parent keeps the same number of genes as they had before and just passes on the new copies to their offspring. Genes are also copied each time a cell divides into two new cells. The process that copies DNA is called DNA replication.
DNA can be copied very easily and accurately because each piece of DNA can direct the creation of a new copy of its information. This is because DNA is made of two strands that pair together like the two sides of a zipper. The nucleotides are in the center, like the teeth in the zipper, and pair up to hold the two strands together. Importantly, the four different sorts nucleotides are different shapes, so in order for the strands to close up properly, an A nucleotide must go opposite a T nucleotide, and a G opposite a C. This exact pairing is called base pairing.
When DNA is copied, the two strands of the old DNA are pulled apart by enzymes which move along each of the two single strands pairing up new nucleotide units and then zipping the strands closed. This produces two new pieces of DNA, each containing one strand from the old DNA and one newly-made strand. This process isn't perfect and sometimes the proteins will make mistakes and put the wrong nucleotide into the strand they are building. This causes a change in the sequence of that gene. These changes in DNA sequence are called mutations. Mutations produce new alleles of genes. Sometimes these changes stop the gene from working properly, like the melanin genes discussed above. In other cases these mutations can change what the gene does or even let it do its job a little better than before. These mutations and their effects on the traits of organisms are one of the causes of evolution.
Genes and evolutionEdit
- Further information: Introduction to evolution
A population of organisms evolves when an inherited trait becomes more common or less common over time. For instance, all the mice living on an island would be a single population of mice. If over a few generations, white mice went from being rare, to being a large part of this population, then the coat color of these mice would be evolving. In terms of genetics, this is called a change in allele frequency—such as an increase in the frequency of the allele for white fur.
Alleles become more or less common either just by chance (in a process called genetic drift), or through natural selection. In natural selection, if an allele makes it more likely that an organism will survive and reproduce, then over time this allele will become more common. But if an allele is harmful, natural selection will make it less common. For example, if the island was getting colder each year and was covered with snow for much of the time, then the allele for white fur would become useful for the mice, since it would make them harder to see against the snow. Fewer of the white mice would be eaten by predators, so over time white mice would out-compete mice with dark fur. White fur alleles would become more common, and dark fur alleles would become more rare.
Mutations create new alleles. These alleles have new DNA sequences and can produce proteins with new properties. So if an island was populated entirely by black mice, mutations could happen creating alleles for white fur. The combination of mutations creating new alleles at random, and natural selection picking out those which are useful, causes adaptation. This is when organisms change in ways that help them to survive and reproduce.
Since traits come from the genes in a cell, if you put a new piece of DNA into a cell, this can produce a new trait. This is how genetic engineering works. For example, crop plants can be given a gene from an Arctic fish, so they produce an antifreeze protein in their leaves. This can help prevent frost damage. Other genes that can be put into crops include a natural insecticide from the bacteria Bacillus thuringiensis. The insecticide kills insects that eat the plants, but is harmless to people. In these plants the new genes are put into the plant before it is grown, so the genes will be in every part of the plant, including its seeds. The plant's offspring will then inherit the new genes, something which has lead to concern about the spread of new traits into wild plants.
The kind of technology used in genetic engineering is also being developed to treat people with genetic disorders in an experimental medical technique called gene therapy. However, here the new gene is put in after the person has grown up and become ill, so any new gene will not be inherited by their children. Gene therapy works by trying to replace the allele that causes the disease with an allele that will work properly.
- ↑ 1.0 1.1 (web resource)University of Utah Genetics Learning Center animated tour of the basics of genetics, Howstuffworks.com, http://learn.genetics.utah.edu/units/basics/tour, retrieved on 2008-01-24
- ↑ 2.0 2.1 How are human eye colors inherited?, Athro Limited, Accessed 20 May 2008
- ↑ Multifactorial Inheritance Health Library, Morgan Stanley Children's Hospital, Accessed 20 May 2008
- ↑ Low income kids' height doesn't measure up by age 1 University of Michigan Health System, Accessed 20th May 2008
- ↑ Frequently Asked Questions About Genetic Disorders NIH, Accessed 20 May 2008
- ↑ Cystic fibrosis Genetics Home Reference, NIH, Accessed 16 May 2008
- ↑ Peto J (June 2002). Breast cancer susceptibility-A new look at an old model. Cancer Cell 1 (5): 411–2.
- ↑ What Are the Risk Factors for Breast Cancer? American Cancer Society, Accessed 16 May 2008
- ↑ 9.0 9.1 9.2 The Structures of Life National Institute of General Medical Sciences, Accessed 20th May 2008
- ↑ Enzymes HowStuffWorks, Accessed 20th May 2008
- ↑ 11.0 11.1 11.2 What is DNA? Genetics Home Reference, Accessed 16 May 2008
- ↑ DNA-RNA-Protein Nobelprize.org, Accessed 20th May 2008
- ↑ What is Albinism? The National Organization for Albinism and Hypopigmentation, Accessed 20 May 2008
- ↑ Mutations The University of Utah, Genetic Science Learning Center, Accessed 20th May 2008
- ↑ 15.0 15.1 Brain, Marshall, "How Evolution Works" (web resource), How Stuff Works: Evolution Library, Howstuffworks.com, http://science.howstuffworks.com/evolution.htm/printable, retrieved on 2008-01-24
- ↑ Mechanisms: The Processes of Evolution Understanding Evolution, Accessed 20th May 2008
- ↑ Genetic Variation Understanding Evolution, Accessed 20th May 2008
- ↑ Long underwear for water Notre Dame magazine, 1998
- ↑ Tifton, Georgia: A Peanut Pest Showdown USDA, accessed 16 May 2008
- ↑ Genetically engineered organisms public issues education Cornell University, Accessed 16 May 2008
- ↑ Staff Gene Therapy. (FAQ) Human Genome Project Information. Oak Ridge National Laboratory. URL accessed on 2006-05-28.
- Jones, Steve (2000). The Language of the Genes, Flamingo. ISBN 0-00-655243-9. (Aventis Prize winner)
- Schwartz, James (2008). In Pursuit of the Gene: From Darwin to DNA, Harvard University Press. ISBN 0-67-402670-5.
- Hamer, Dean and Copeland, Peter (1999). Living with Our Genes: Why They Matter More Than You Think, Anchor. ISBN 0-38-548584-0.
- Goodsell, David (1996). Our Molecular Nature: The Body's Motors, Machines and Messages, Springer. ISBN 0-38-794498-2.
- Introduction to Genetics, University of Utah
- Introduction to Genes and Disease, NCBI open book
- Genetics glossary, A talking glossary of genetic terms.
DNA and genes
- (web resource)Understanding Evolution: your one-stop source for information on evolution, The University of California Museum of Paleontology, Berkeley, http://evolution.berkeley.edu/evolibrary/article/0_0_0/evo_01, retrieved on 2008-01-24
- What Color Eyes Would Your Children Have? Genetics of human eye color: An interactive introduction.
- Double Helix Game from the Nobel Prize website. Match CATG bases with each other, and other games.
- Transcribe and translate a gene. University of Utah
|* Evolutionary psychology|
|Fields of genetics|
|Genetics in psychology|
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The US House of Representatives Oversight and Homeland Security Committees held a joint hearing on Friday on the implications of the ongoing SolarWinds hack for the government and private industry.
The hack, which was discovered by private security company FireEye in December, has ravaged roughly 18,000 customers and at least nine government agencies.
SolarWinds is a US-based company that develops system management software for use in businesses and organisations. Authorities have said the attack gathered intelligence, but they have yet to give specifics.
Representative Carolyn B Maloney, chairwoman of the Oversight Committee, said “a sophisticated attacker reported to be the Russian government broke into the SolarWinds system and inserted malicious code into its software … nearly 18,000 customers downloaded updates containing the malicious code”.
Maloney said the hack, which was spread through a vulnerability in widely used Microsoft cloud software, affected law enforcement agencies, and more than 100 private companies involved “in foreign affairs and national security … And that’s just what we know. There’s much more that we still don’t know. We still don’t know if they’re still in the system.”
Eleanor Norton, the District of Columbia’s delegate to the House who is a member of the Oversight committee, said “the information I’ve been given, is that the breaches included the Department of Energy, including a component responsible for managing the nation’s nuclear weapons” and the “roughly 3,500 accounts” from the Justice Department.
Lawmakers on both committees pressed representatives of SolarWinds, Microsoft and FireEye on how to prevent these attacks from happening in the future.
Microsoft President Brad Smith told the joint hearing his company needs to focus on securing the software supply chain, but what “we need to do is think much more broadly, we need to focus on the modernisation of the information technology infrastructure. And we need to apply more broadly cybersecurity best practices.”
For example, most cybersecurity experts recommend two-factor authentication and complex passwords. Reuters reported the company was informed in 2019 that its updates server password, “solarwinds123”, was highly vulnerable.
Reuters further reported hackers have claimed they could sell access to SolarWinds’ computers since 2017 by faking the identity of authorised employees to gain access to cloud services.
Smith said in the US “today there’s a shortage of more than 300,000 trained cybersecurity personnel. And this is something that we as a tech company like Microsoft can focus on addressing by helping colleges and universities, high schools, and others, develop the people we will need in the future.”
Smith previously said investigators estimate at least 1,000 highly skilled engineers would have been required to develop the code used to hack SolarWinds.
US national security officials have also said Russia was likely responsible for the breach, and President Joe Biden’s administration is weighing punitive measures against Russia for the hack as well as other activities.
Russia has denied responsibility for the breach.
China, too, has reportedly gained access to US government files through the vulnerability. Beijing has denied this.
The hack was downplayed by former President Donald Trump, whose administration demoted cybersecurity as a policy field.
Biden has announced cybersecurity will be a priority in his administration. Under a recent law, Biden must open a cyber-focused office reporting to a new National Cyber Director, who will coordinate the federal government’s vast cyber capabilities. | <urn:uuid:1310e29b-576c-4b1a-825d-1ba6743d5557> | CC-MAIN-2022-33 | https://www.aljazeera.com/news/2021/2/26/they-may-be-in-the-system-questions-remain-on-solarwinds-hack | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570879.37/warc/CC-MAIN-20220809003642-20220809033642-00676.warc.gz | en | 0.965141 | 725 | 2.125 | 2 |
Why not do some watching this week and find out what exactly are the preferred words spoken and you will written in your organization. How exactly we primary and physique organizational commentary molds new society and concentrate with the security.
While i have always been basic lead so you’re able to an organisation I love to speak about their social artifacts (something to the wall space, icons, charts, formula and you can stuff) and you can precisely what the organisation states throughout the on their own. I discover terms (and you will hidden text) which is found in a keen enterprises self-declarations. Even more important, In addition listen and look for terminology which can be forgotten regarding its items, files, regulations and you will assistance. A few of the keywords We check for is the following the: ‘learning’, ‘understanding’, ‘tolerance’, ‘together’, ‘listening’, ‘helping’, ‘share’, ‘respect’, ‘belonging’, ‘collaboration’ and you will ‘forgiveness’. Such are not just the words we need to take care of dating when you look at the our daily lives, these are the ‘glue’ out-of organisational capabilities.
It is very worthwhile to look at spacial design off offices, workspaces, workflow diagrams, organizational charts and different suggests society are presented visually. You can study much throughout the an organization in what was perhaps not told you, once you learn what you are lookin and hearing having. When organizations have only constant repetitions from words such as for instance ‘compliance’, ‘vigilance’, ‘policing’, ‘zero’ and you will ‘control’, we understand what’s going on.
Among the best evidence out of an enthusiastic companies method to management inside exposure and you may safety ‘s the method they normally use prepositions. Prepositions was conditions that predate an excellent noun or pronoun and show the partnership and you may hook up of men and women to people and individuals to things. How we explore prepositions ways a great deal throughout the our society, score, opportunities and you can updates inside chance, safety and you can management. Management inside risk and you will safeguards is basically a social craft and so that the means i fool around with prepositional relationships in the vocabulary suggests new actual discourse in chance in the an organization. The audience is what we walk and you will talk.
What exactly do the existence of the following prepositions suggest getting chance and you can security commentary about people i work on?
The new focus ones prepositions are authoritarian in nature. When positions away from risk and you may cover is actually ‘over’ and you can ‘controlling’ anyone else there is certainly absolutely nothing sympathy floating around. The fresh new authoritarian otherwise ‘f’ sort of just like the documented by the Adorno, Levinson, Brunswick and others try live and you can well in such organizations. There clearly was no safety ownership regarding authoritarian organization, individuals are just safe if the skilled almost every other is just about. Like organisations was specialists at ‘dumbing down’ this new personnel. The fresh new assumption is that folks are dumb except me personally.
Our very own functions, organization and you can team, as well as cover, simply feel as effective as the standard of our very own relationships, this is because the origin of all of the coverage is actually trust
The latest focus ones prepositions concerns knowing we’re particularly one another, you will find skills and faith you to ‘there however, because of the elegance from god go I’. You don’t need to to own quality that have like prepositions because believe and you can possession may be the first step toward relationships. Whenever we deal with might properties from human shared fallibility, we think in different ways on chance and you will cover, independence and you may handle.
While the business chart and you can shell out measure elizabeth facial skin, words, information, ailments and you may stop. While i was at Tallin during the Estonia We noticed one unbelievable paint ‘This new Dancing of Death’ during the St Nicholas’s Church. It fragment of brand new 30 metre color was mesmerising. We stood around having an hour simply performing the help of its incredible has as well as have a printing from it on the wall out of my personal research. So it fifteen th 100 years visual portrays the nobles, royals, clergy and you may officials getting visited by the Black colored Passing, The brand new Plague. There’s zero discrimination considering classification otherwise riches, all the was basically vulnerable and you may human. I speak about this simply because possibly we get a mysterious proven fact that brilliance is achievable (zero) immediately after which act like absolutes is actually achievable. Like delusions are always defeated by-time. The fresh new priming of these code eventually causes quality, popularity and you will concealing.
Individuals who know of one’s own vulnerability find out the provide regarding offering, studying and you can bondage com recenze helping. There’s no added a healthy and balanced relationships to have prominence and you will one-way guests.
These prepositions when included in relationships basically mean submission
These types of prepositions often indicate disagreement additionally the simple fact that here shortly after was a romance but it’s today busted. This new focus out of huge difference contributes to section, the brand new increased exposure of resemblance and you can likeness contributes to harmony and matchmaking. The task away from Cameron and you will Quinn is actually foundational learning for those interested in people and you may organizational health. What they do provides advanced level systems with the analysis out of contending thinking and specifications in the organizations. The theory that there exists just binary requirements (eg. zero) and digital viewpoints (eg. safety) is actually a nonsense. Most of the strategy to have my personal MiProfile business people survey are predicated on their work. Whenever we learn discover things ranging from all of us, that not be a challenge, practical question is exactly what will we perform about any of it? Whenever we explore recommendations and you may electricity that’s ranging from me to push some body away and you may at the rear of all of us then there is zero relationship nor probability of recovery.
Those things regarding united states and you can stuff i focus on even though the hopefully shared are not person, so the work at things in complete safety does not sound right. I just bought a safety text-book (blogged big date 2014) and also as I looked inside was not shocked of the content material. The ebook starts with laws and regulations! As to the reasons doesn’t the protection business get it, the publication is start with some body. Once i waded from publication I was not amazed, little into the active collaboration, communication, experiences regarding involvement, information decision making, dating or what makes some body tick only 350 pages regarding laws and you can conformity. Worst absolutely nothing security, policeman out-of an act and you can detectives out of stuff (hazards).
You need to do a bit of watching recently and view exactly what are the most popular words spoken and you may printed in their organisation. The way we finest and you can figure business discourse molds brand new culture and focus to your coverage. | <urn:uuid:ee2148d3-9fe4-4628-805c-e88449c4baa2> | CC-MAIN-2022-33 | https://sarahburnellband.ca/2022/08/prepositions-suggest-updates-room-way-and-you-can/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571190.0/warc/CC-MAIN-20220810131127-20220810161127-00074.warc.gz | en | 0.955285 | 1,555 | 2.25 | 2 |
Russia is among the top three nations where press freedom has deteriorated the most over the last five years, reports RFE/RL.
A new report, compiled by the New York-based Committee to Protect Journalists to mark World Press Freedom Day today, found that almost a dozen journalists in Russia have been murdered since 2002. The report focuses on the 10 countries where press freedom has most deteriorated. Russia stands in third place, below Ethiopia and Gambia.
The U.S. State Department also criticized Russian media freedom this week and expressed “grave concern” over the October killing of investigative reporter Anna Politkovskaya.
May 3, 2007
Russia is among the top three nations where press freedom has deteriorated the most over the last five years, reports RFE/RL.
Apr 18, 2007
The violent crackdown on last weekend's March of the Dissenters points to the increased paranoia of the Russian government elite ahead of the December 2007 parliamentary and the March 2008 presidential elections, according to Moscow Times' columnist Georgy Bovt. The use of excessive force of the security troops and the careful planning of the crackdown show that Kremlin elite is not willing to leave anything to chance.
There is a question of 'why'. Putin's standing remains high, Russian economy is booming and foreign investors keep pouring funds into the Russian stock market. As Sonja Margolina writes in Frankfurter Rundschau (here is the original article in German) "only through a monstrous hall of mirrors could one see in the handful of opposition members without resources and support, anything approaching "orange revolutionaries" or Western-influenced conspirators." She sees the late events as a "symptom of the political crisis that seems to be gripping the Putinesque vertical at the nadir of its un-challenged power."
at 5:15 PM
Apr 17, 2007
The White House voiced criticism of this weekend's events in Moscow and St. Petersburg. The White House spokeswoman Dana Perino specifically talked about the emerging pattern of excessive force used by the Russian authorities and the crackdown on the freedom of press. Read more here...
However, as the AP article reports "opinion polls rate Putin as Russia’s most popular political figure by far, thanks to newfound political stability and rapid economic growth fueled by high world oil prices. That popularity has cowed mainstream politicians in parliament and allowed Putin to strengthen the Kremlin’s powers."
at 9:30 PM
Stratfor, the intelligenece consulting company, gives a rather chilling perspective of the recent crackdown on Russian opposition in Moscow and St.Petersburg. According to the writer of the report, Peter Zeihan, the events not only showed that the Russian opposition is isolated and weak but rather that the Kremlin is sending a deliberate message to its critics in Russia and abroad.
Russian opposition members rallied in Moscow's Pushkin Square on April 14. The so-called Dissenters' March was organized by Other Russia, an umbrella group that includes everyone from unrepentant communists and free-market reformers to far-right ultranationalists whose only uniting characteristic is their common opposition to the centralization of power under President Vladimir Putin's administration.
Minutes after the march began, the 2,000 or so protesters found themselves outnumbered more than four to one by security forces. They quickly dispersed the activists, beating and briefly detaining those who sought to break through the riot-control lines. Among those arrested were chess-champion-turned-political-activist Garry Kasparov and Maria Gaidar, the daughter of Russia's first post-Soviet reformist prime minister. Former Prime Minister Mikhail Kasyanov only avoided arrest because his bodyguards helped him to escape. A Reuters crew was permitted to capture the events and disseminate them to the West. A day later, another protest, albeit far smaller, was broken up in a similar way in St. Petersburg, though Kasparov was detained before the protest even began.
What gives? The protests were insignificant in both numerical and political terms. Moreover, with all that is going on in the world right now, the last thing the Putin government needs is to attract negative attention to itself. The answer becomes apparent when one considers Russia's point in its historical cycle and the mounting pressures on Putin personally that have nothing whatsoever to do with "democracy."
The Russian Cycle
At the risk of sounding like a high school social studies teacher (or even George Friedman), history really does run in cycles. Take Europe for example. European history is a chronicle of the rise and fall of its geographic center. As Germany rises, the powers on its periphery buckle under its strength and are forced to pool resources in order to beat back Berlin. As Germany falters, the power vacuum at the middle of the Continent allows the countries on Germany's borders to rise in strength and become major powers themselves.
Since the formation of the first "Germany" in 800, this cycle has set the tempo and tenor of European affairs. A strong Germany means consolidation followed by a catastrophic war; a weak Germany creates a multilateral concert of powers and multistate competition (often involving war, but not on nearly as large a scale). For Europe this cycle of German rise and fall has run its course three times -- the Holy Roman Empire, Imperial Germany, Nazi Germany -- and is only now entering its fourth iteration with the reunified Germany.
Russia's cycle, however, is far less clinical than Europe's. It begins with a national catastrophe. Sometimes it manifests as a result of disastrous internal planning; sometimes it follows a foreign invasion. But always it rips up the existing social order and threatens Russia with chaos and dissolution. The most recent such catastrophe was the Soviet collapse followed by the 1998 financial crisis. Previous disasters include the crushing of Russian forces in World War I and the imposition of the Treaty of Brest-Litovsk; the "Time of Troubles," whose period of internal warfare and conspiracy-laden politics are a testament to the Russian predilection for understatement; and near annihilation under the Mongol occupation.
Out of the horrors of defeat, the Russians search desperately for the second phase of the cycle -- the arrival of a white rider -- and invariably they find one. The white rider rarely encapsulates what Westerners conceive of as a savior -- someone who will bring wealth and freedom. Russian concerns after such calamities are far more basic: they want stability. But by Russian standards, the white rider is a rather optimistic fellow. He truly believes that Russia can recover from its time of trial, once a level of order is restored. So the Russian white rider sets about imposing a sense of consistency and strength, ending the free fall of Russian life. Putin is the current incarnation of Russia's white rider, which puts him in the same category as past leaders such as Vladimir Lenin and, of course, Russia's "Greats": Catherine and Peter.
Contrary to portrayals of him by many in the Western media, Putin is not a hard-nosed autocrat set upon militarization and war. He is from St. Petersburg, Russia's "window on the West," and during the Cold War one of his chief responsibilities was snagging bits of Western technology to send home. He was (and remains) fully cognizant of Russia's weaknesses and ultimately wanted to see Russia integrated as a full-fledged member of the Western family of nations.
He also is pragmatic enough to have realized that his ideal for Russia's future and Russia's actual path are two lines that will not converge. So, since November 2005, Putin has been training two potential replacements: First Deputy Prime Ministers Dmitri Medvedev and Sergei Ivanov. At this point, nearly a year before Russia's next presidential election, determining which one will take over is a matter of pure guesswork. Also unclear is what role, if any, Putin will grab for himself -- up to and including a continuation of his presidency.
The question of who takes over in March 2008 is generating much interest and debate among Kremlinologists. It clearly matters a great deal both politically and economically, though geopolitically the discussion misses the point. The real takeaway is that Russia's current white horse period is coming to an end. Putin's efforts to stabilize Russia have succeeded, but his dreams of Westernizing Russia are dead. The darkness is about to set in.
The Dark Rider
In the third phase of the Russian cycle, the white rider realizes that the challenges ahead are more formidable than he first believed and that his (relative) idealism is more a hindrance than an asset. At this point the white rider gives way to a dark one, someone not burdened by the white rider's goals and predilections, and willing to do what he feels must be done regardless of moral implications. The most famous Russian dark rider in modern times is Josef Stalin, of course, while perhaps the most consuming were the "Vasilys" of the Vasily Period, which led to the greatest civil war in Russian medieval history. In particularly gloomy periods in Russia's past (which is saying something) the white rider himself actually has shed his idealism and become the dark rider. For example, Ivan the IV began his rule by diligently regenerating Russia's fortunes, before degenerating into the psychotic madman better known to history as Ivan the Terrible.
Under the rule of the dark rider, Russia descends into an extremely strict period of internal control and external aggression, which is largely dictated by Russia's geographic weaknesses. Unlike the United States, with its deep hinterland, extensive coasts and lengthy and navigable river networks, Russia's expansive barren landscape and lack of maritime transport options make trade, development and all-around life a constant struggle. Russia also lacks any meaningful barriers to hide behind, leaving it consistently vulnerable to outside attack.
Understanding that this geographic reality leaves Russia extremely insecure is critical to understanding Russia's dark periods. Once the dark rider takes the state's reins, he acts by any means necessary to achieve Russian security. Internal opposition is ruthlessly quashed, economic life is fully subjugated to the state's needs and Russia's armies are built furiously with the intent of securing unsecurable borders. That typically means war: As Catherine the Great famously put it: "I have no way to defend my borders except to extend them."
After a period of unification and expansion under the dark rider, Russia inevitably suffers from overextension. No land power can endlessly expand: the farther its troops are from core territories, the more expensive they are to maintain and the more vulnerable they are to counterattack by foreign forces. Similarly, the more non-Russians who are brought under the aegis of the Russian state, the less able the state is to impose its will on its population -- at least without Stalin-style brute force. This overextension just as inevitably leads to stagnation as the post-dark rider leadership attempts to come to grips with Russia's new reality, but lacks the resources to do so. Attempts at reform transform stagnation into decline. Stalin gives way to a miscalculating Nikita Khrushchev, a barely conscious Leonid Brezhnev, an outmatched Mikhail Gorbachev and a very drunk Boris Yeltsin. A new disaster eventually manifests and the cycle begins anew.
Why the Crackdown?
The April 14-15 protests occurred at an inflection point between the second and third parts of the cycle -- as the white rider is giving way to a dark rider. Past Russian protests that involved 2,500 total people at most would have been allowed simply because they did not matter. The Putin government has a majority in the rubber-stamp Duma sufficient to pass any law or constitutional change in a short afternoon of parliamentary fury. All meaningful political parties have been disbanded, criminalized or marginalized; the political system is fully under Kremlin control. The Kasparov/Kasyanov protests did not threaten Putin in any meaningful way -- yet in both Moscow and St. Petersburg a few dozen people were blocked, beaten and hauled off to court.
This development was no accident. Roughly 9,000 riot police do not spontaneously materialize anywhere, and certainly not as the result of an overenthusiastic or less-than-sober local commander. A crackdown in one city could be a misunderstanding; a crackdown in two is state policy. And one does not send hundreds of batons swinging but allow Reuters to keep filming unless the objective is to allow the world to see. Putin chose to make these protests an issue.
Putin, then, is considering various groups and rationalizing his actions in the context of Russia's historical cycle:
* The West: Putin certainly does not want any Western capital to think he will take exiled oligarch Boris Berezovsky's recent threats of forcible revolution lying down. Berezovsky says violence is a possibility -- a probability even -- in the future of regime change in Russia? Fine. Putin can and did quite easily demonstrate that, when it comes to the application of force in internal politics, the Russian government remains without peer.
* The people: Putin knows that governance is not so much about ruling as it is about managing expectations. Russians crave stability, and Putin's ability to grant that stability has earned him significant gravitas throughout Russia as well as a grudging respect from even his most stalwart foes. He is portraying groups such as the Other Russia as troublemakers and disturbers of the peace. Such explanations make quite attractive packaging to the average Russian.
* The opposition: It is one thing to oppose a wildly powerful and popular government. It is another thing when that government beats you while the people nod approvingly and the international community barely murmurs its protest. Putin has driven home the message that the opposition is not just isolated and out of touch, but that it is abandoned.
* The Kremlin: Just because Putin is disappointed that his dreams are unattainable does not mean he wants to be tossed out the proverbial air lock. Showing any weakness during a transition period in Russian culture is tantamount to surrender -- particularly when Russia's siloviki (nationalists) are always seeking to rise to the top of the heap. Putin knows he has to be firm if he is to play any role in shaping Russia during and after the transition. After all, should Medvedev and Ivanov fail to make the grade, someone will need to rule Russia -- and the only man alive with more experience than Putin has a blood-alcohol level that precludes sound decision-making.
at 9:14 PM
Apr 16, 2007
Der Spiegel summarized the reaction of the German press to last weekends crackdowns on opposition protests in Moscow and St. Petersburg.
And Garry Kasparov discusses with Der Spiegel Other Russia's prospects, corruption in the Putin administration and upcoming elections.
at 11:05 AM
Apr 15, 2007
The inevitable comparisons of Putin's Russia and the Soviet Union are beginning to appear. This is an editorial in today's Times:
Like the end of history, the end of the cold war turns out to have been little more than western wishful thinking. And like history, the cold war seems to be repeating itself. Once again chilly winds are blowing across the steppes and over the rest of the world; perestroika and glasnost are little more than memories. Russia today is beginning to resemble the old Soviet Union — repressive at home and aggressive abroad. President Putin is quick to stamp on opposition. One has only to think of Anna Politkovskaya, of Mikhail Khodorkovsky and of Alexander Litvinenko. Read more...
at 1:36 PM
As expected, the police cracked down on participants of the March of Dissent rally in St. Petersburg linked to the Kremlin opposition group Other Russia. Yesterday, the police arrested dozens of protesters in Moscow, among them Other Russia's leader Gary Kasparov. The Washington Post and RFE/RL offer a comprehensive account of the recent events.
at 11:59 AM | <urn:uuid:ed3aa50f-1d24-4eb7-be05-8a62ff05b3ae> | CC-MAIN-2017-04 | http://russianstandard.blogspot.com/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281419.3/warc/CC-MAIN-20170116095121-00493-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.956149 | 3,280 | 1.6875 | 2 |
As you read these words, right now– do you think you’re receiving the most out of your quick Fat loss diets? If you don’t know the solution, its smart to consider a straightforward, cheap option to make sure that you are. I am going to explain how this easy, doctor-proven methodology may be your strongest weapon in your struggle against fat. No matter what Fat reduction program you are at this time on, I bet you wish to know if your scheme is manufacturing results? Quite a few of us step on the scale, or wait till our clothing fit more freely, before we actually know whether our last miracle Fat reduction tablet or plan is working. You can collect complete information about the fat burners from Apnews to purchase the right one. It provides a lot of benefits to the individuals in maintaining good health and other effective results. The reduction in the fat is possible according to the needs and requirements of the people.
You are usually either using up fat, or “losing” muscle.
Just in case you are burning muscle, look out! You have truly started to starve. For safe, healthy Fat control, you should preserve your muscle tissue ( including heart muscle ) and shed calories instead. Listed here are the medical facts: any time your body consumes calories, chemicals called ketones are produced. Ketones are by-products of utilizing fat. An excellent fast Fat loss diet, is lower in nutrients like pastas, cheese, red meats, milk and lard than an ordinary EU diet, which some believe account for the variations in longevity and health.
Eat like Crete, using a low carbohydrate twist.
Buy sticking to reduced glycemic carbohydrates like beans and cereals, will usually results in a lower insulin level- which can be connected to the storage of fat in our bodies. Better still, when it’s altered to lower carbohydrates, it’ll hasten Fat loss while continuing to provide positive benefits to the heart. So get the best of two worlds.
Now you know what you may add to your diet, it is crucial to know what to take away from your daily diet for great health. You will need to eliminate foods that contain cholesterol. A sensible diet also is consists of foods that are loaded in fiber, as well as minerals and vitamins. Foods with cholesterol include numerous fried foods; and many break foods which are processed and have a high amount of trans fat too.
A sensible eating plan is only going to work the moment you’re comfortable enough in your current diet to get rid of foods that just aren’t useful to you.
The more engaging you make your diet, the simpler it’s going to be for you to stop eating processed foods. Try to remember that nourishment isn’t the only part of great health. When you are discovering which diet works best for you, incorporate your good diet habits with exercising daily, and decreasing everyday stress by organizing your day industriously; and at the same time, setting aside time to spend with friends and family.
Nourishment and great diet are indeed factors which will allow you to reach your Fat loss and health goals, but they need practice. So make sure to have some fun testing new dishes and foods while you’re on your way to settling on which of the quick Fat loss diets is best for you. | <urn:uuid:ca8641e8-793d-4e19-b5da-85af85317219> | CC-MAIN-2022-33 | http://anigp-tv.com/quick-fat-loss-diets-do-they-really-work-know-the-working/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570793.14/warc/CC-MAIN-20220808092125-20220808122125-00668.warc.gz | en | 0.948473 | 689 | 1.734375 | 2 |
After School Care
Our After School program runs Monday through Friday from 2:30 to 6:30 pm at St. James Episcopal Church. Students from both private and public schools in Montgomery County are welcome to attend the After School Care program. You may arrange for Celebrate Ability to be their drop-off location via MCPS transportation.
The hours following normal school hours can be productive for kids. As a result, in After School Care, we provide activities that help kids maximize their potential after having spent their whole day in a classroom. We assist them with their homework, take fun community trips, and facilitate individual and group games. We ensure that they engage in activities that will help develop their intellectual, social, emotional, and physical skills alongside same-age peers.
Snacks are provided for participants and our camp follows the MCPS schedule. See our School Year Schedule for more details. After the program, transportation home may be arranged on a case-by-case basis with Celebrate Ability.
All of our camps offer engaging activities and knowledgeable specialists.
Click on each activity to learn more: | <urn:uuid:a3995a53-8508-4819-bf92-4b0b4c6ec98d> | CC-MAIN-2022-33 | https://www.celebrateability.org/after-school-care/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571472.69/warc/CC-MAIN-20220811133823-20220811163823-00677.warc.gz | en | 0.947941 | 222 | 1.75 | 2 |
RENAISSANCE will mature its approach through three tiers of demonstrators, which will bring its TRL from level 6 (Technology demostration) to level 9 (system test, launch and operations). Starting from the one in Brussels, RENAISSANCE will be demonstrated in further three demonstrator pilot sites.
System analysis and design
As first step already at project start, energy communities will be actively engaged in the Multi Actor Multi Criteria Analysis (MAMCA) to evaluate demonstrator’s business ecosystems, promoting consumer/prosumer participation and building consensus around site-specific new business cases.
Secondarily demonstrators will be analysed with a multi energy site analysis tool, a software already used to optimize LES configuration, to set the basis for the design process of the Renaissance Energy Island Software Replicator, namely ReEnergise.
Thanks to the open-source public data available from theVrije Universiteit Brussels (VUB), such enhanced tool will turn energy flows between nodes into monetary values and spatial information will help assess profitability of new business models. As a result, for any type of microgrid considered, it will provide energy communities an informed guidance and increase overall efficiency.
Based on a secure, interoperable and scalable blockchain architecture the RENAISSANCE platform will be developed to interconnect all existing demonstrators’ energy vectors into a unique decentralized multi-vector energy services market where consumers/prosumers will interact and perform financial actions defined by smart contracts, which limits are established in real time.
The platform will regulate the energy service trade market dynamically and transparently ensuring effective operations at minimum cost. At the end of this phase, the set of solutions provided will be used to simulate additional scenarios of energy interactions and help identifying those barriers hindering energy island potentials.
In this phase the set of tools improved along the project will be validated by partners through the design and operation of local energy systems in the four Pilot Sites, where technical, energetic, economic and social aspects are considered under market realistic circumstances.
Moreover, the hardware/software infrastructure will be rolled-out to validate the security of the financial transactions and the stakeholders’ level of acceptance and involvement.
Replicability is a core objective of the project. Providing a set of solutions enabling the analysis and management of energy islands, software solutions and ICT integration, RENAISSANCE will help optimizing design and operation, minimizing LLCOE and infrastructure investments.
Virtual demonstrators in Eastern and Southern Europe, India, South America, and Africa will demonstrate the value of RENAISSANCE set of solutions to any type of local energy system at any country. | <urn:uuid:ccbead3a-0d33-4835-aaeb-4d154bcdd09c> | CC-MAIN-2022-33 | https://www.renaissance-h2020.eu/methodology/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570651.49/warc/CC-MAIN-20220807150925-20220807180925-00479.warc.gz | en | 0.874619 | 544 | 1.570313 | 2 |
DONALDSONVILLE, La. – It will be at least Saturday or Sunday before residents of Donaldsonville can be sure their tap water is safe to drink, Louisiana’s health officer said Thursday.
Dr. Jimmy Guidry said the state has approved a plan by the privately run Peoples Water Service Co. to begin disinfecting with a different chemical — chlorine instead of chlorine dioxide. And was expected to take two to three days to implement the plan and do needed testing.
The system serves about 10,000 customers in the town southeast of Baton Rouge. Residents there were advised Tuesday not to drink the water after an inspection showed the possibility that it contained chlorine dioxide levels four to five times Environmental Protection Agency guidelines.
The state said exposure to elevated levels of the chemical can cause serious health effects to the nervous systems of some infants, young children and the fetuses of pregnant women.
Guidry said the “do not drink” advisory was issued out of an “abundance of caution.” He said an initial test by the company showing an elevated chlorine dioxide level was not properly followed up with more tests.
“If they had done those tests, then we’d have some answers,” Guidry said in an interview.
Mayor Leroy Sullivan declared a state of emergency Tuesday night.
Company officials did not respond to requests for comment submitted Thursday afternoon by telephone and through its website. On its website, the company said operators will be retrained on sampling, testing and reporting procedures and that supervisors have put in place a new method to monitor operator testing results. | <urn:uuid:cabc2623-2cf3-453e-b08b-54412640e6e1> | CC-MAIN-2017-04 | http://www.oddonion.com/2016/03/24/donaldsonville-may-get-ok-to-drink-tap-water-in-2-3-days/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280900.71/warc/CC-MAIN-20170116095120-00008-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.965344 | 328 | 1.757813 | 2 |
Estimated reading time: 6½ minutes
Chicken nuggets have become a popular choice worldwide, as the trend for hand-held fast food has grown. But what do we really know about how they are made, and the impact they have on our health, the environment and on animals?
What Are Chicken Nuggets Made Of?
The meat inside nuggets, unsurprisingly, comes from chickens. It can be pieces of ground-up meat but often it is “mechanically recovered meat” or MRM. This is the remaining shreds of flesh that are blasted off the bone after the carcass has been butchered.
How Are Chicken Nuggets Made?
The reason chicken nuggets are so cheap is because of factory farming, and the reason they are so tasty is because they taste nothing like chicken meat. Let’s take a look at the whole process, from living beings through to heavily marketed ‘nuggets’.
Take A Chicken From A Crowded Confinement
Almost all chickens in the US, Europe and elsewhere are confined inside factory farms where they are kept alive but none of their other needs are met. Because tens of thousands of birds are held together in each shed, and there may be a dozen or more sheds on each farm, their lives are cheap. The birds do not get individual care and attention, and millions suffer to death right there in the sheds, unable even to survive six weeks in the squalid conditions. Six weeks? Yes, these birds have been genetically manipulated to put on weight fast which makes their bodies balloon (and their hearts fail and their limbs break) but despite their size, they are just babies when they are killed.
Feed Her Low-nutrition Food And Antibiotics
The margin of profit for each bird is so small that every cost is carefully managed. The feed given to the birds needs only to ensure their weight rises dramatically, it does not need to sustain them healthily. And so their feed is made up of cheap ingredients, including significant quantities of soy, much of it grown on deforested lands and shipped around the world. And because of those conditions – immunocompromised birds packed in together in filthy surroundings, often with no fresh air, and nothing to exercise body or mind – the birds are routinely fed antibiotics, in a bid to keep as many as possible alive through those six short weeks. The widespread use of antibiotics in farmed animals helps drive antibiotic-resistant pathogens in people. Already, drug-resistant bacteria sicken 2.8 million Americans each year, and kill around 35,000 people, according to the Centers for Disease Control and Prevention.
Dispose Of Sick And Dead Chickens
Unsurprisingly, in those conditions, many birds succumb. Their bodies are simply thrown in the dead bins or left to rot where they lay. Even birds who are ailing but still alive have been found tossed in the trash, and left to suffocate under the weight of their dead companions. It truly is a heartless industry.
Kill The Chosen Chicken
At the end of the six-week cycle, the sheds are emptied. The birds are packed into crates, either physically by catching gangs who work fast, grabbings birds by their legs and wings, or mechanically, where the animals are swept up by machinery. Once packed tightly into a crate, many already suffering broken legs and wings, the birds are loaded onto trucks and transported through all weathers – blistering heat, driving rain and unbearable cold – over long distances to get to the slaughterhouse. There, they may be shackled upside down while still conscious, and their throats are cut. Attempts at stunning do not work for every bird. Some slaughterhouses gas the birds to death in specially-constructed chambers.
Pluck The Chicken In Boiling Water
Once they have been bled, the birds’ bodies are tipped into hot water baths to loosen their feathers, and then it is on to the butchery line.
Deboning And Grinding
The meat is cut, stripped and blasted off the bones. Any parts that can be profited from are cut out, including the feet, and then the meat destined for nuggets is ground down.
Season To Mask The Flavor
Flesh does not taste great on its own. To make it palatable, it has to be flavored and it is the seasonings used that make nuggets so tasty. The good news is that all those seasonings come from plants, and so it is easy to create vegan chick*n nuggets that have all the taste and texture and none of the suffering or environmental impact.
Shaping And Frying
The minced meat paste is cut into cute shapes, to make them handleable and easy to consume, and then they are fried. We tend to crave high-fat products like these – a throwback to our evolutionary history when finding calorie-dense foods was beneficial – but today they come with considerable health implications.
The Truth About Chicken Nuggets
There some pretty unsavory truths about chicken nuggets.
The Pink Slime
According to the USDA, mechanically recovered meat, also known as mechanically separated meat, is “a paste-like and batter-like meat product produced by forcing bones, with attached edible meat, under high pressure through a sieve or similar device to separate the bone from the edible meat tissue.” This looks like, and has become known as, pink slime. And it is this slime that is shaped and coated and sold to us as food.
The Environmental Impact
Research shows that almost every animal product – including chicken – is worse for the planet than almost every plant product. Chicken meat, for example, produces three times more climate-changing emissions than tofu, and it is inextricably linked with deforestation, as much of the feed shipped to factory farms around the world contains soy grown on deforested lands. When trees are cut down, wildlife is lost. Chicken farms are also renowned water and air polluters, and this also has a profoundly negative impact on wildlife. Overall, chicken farms are really bad news for the planet.
Are Chicken Nuggets Bad For You?
They’re certainly not a health food! In 2015, The World Health Organization confirmed that all processed meats – such as chicken nuggets – cause colorectal cancer, and there is also an association with stomach cancer. Plus, there is strong evidence to suggest a connection between a higher consumption of fried foods and chronic diseases, including type 2 diabetes, obesity, high blood pressure, and heart failure.
And let’s not forget the pathogens associated with handling and eating chicken – things like salmonella, campylobacter and E.coli. These are responsible for making millions of people sick every year.
There is a broader health risk, too. When we consider that chicken farms are associated with serious pandemic risk and also contribute to antibiotic-resistant pathogens emerging, we can see just how dangerous the chicken farming industry is.
The Animal Cruelty
Most people hate factory farming, and know that the animals confined inside such facilities have a miserable life. And yet, we are so disconnected from our food systems that we may not realize that almost every single piece of chicken consumed in the US, Europe and elsewhere comes from this very system we dislike.
Tens of thousands of birds are packed into each unit. There is no enrichment, nothing to occupy their bright, inquisitive minds. The birds are permitted nothing but food and they are allowed to live just six weeks. Because they have been purpose-bred to put on weight fast, their hearts and bones come under enormous pressure. All too often hearts fail and legs break under the strain. Just imagine standing your whole life on broken legs, with no pain relief, no care at all. It’s a pitiless industry that causes immense suffering.
When we weigh up the pros and cons of chicken nuggets, we balance taste against animal suffering, environmental degradation, personal and public health. So, what if we could avoid all the bad stuff and still get the flavor we love? We can. There are many companies producing super tasty vegan fried chick*n that looks, cooks and tastes like chicken, but does not come with the raft of negatives.
There is a phrase we love and feel inspired by: “be the change you want to see in the world.” If we don’t want to live in a world where animals endure factory farming and slaughter, where one reckless industry pollutes and poisons our planet and raises serious public health risks, we can do something: we can simply stop supporting it.
Interested in finding out more? We recommended reading Fast Food Nation by Eric Schlosser | <urn:uuid:c6de0fd8-25c1-445e-93a4-8cebc8160660> | CC-MAIN-2022-33 | https://www.vegan-news.net/how-are-chicken-nuggets-made-and-what-are-they-made-of/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570977.50/warc/CC-MAIN-20220809124724-20220809154724-00469.warc.gz | en | 0.95896 | 1,790 | 3.234375 | 3 |
- Copyright © 2015 The Paleontological Society. All rights reserved.
The Guadalupian (middle Permian) extinction may have triggered substantial ecological restructuring in level-bottom communities, such as turnover in dominant brachiopod genera or a shift from abundant brachiopods to mollusks, despite comparatively minor taxonomic losses. However, ecological changes in relative abundance have been inferred from limited data; as a result, constraints on important shifts like the brachiopod-mollusk transition are imprecise. Here, I reevaluate the magnitude of ecological shifts during the Guadalupian–Lopingian (G-L) interval by supplementing previous census counts of silicified assemblages with counts from non-silicified assemblages and global occurrence data, both sourced from the Paleobiology Database. Brachiopod occurrences are consistent with more pronounced faunal composition changes from the Guadalupian to Lopingian than among stages within those intervals, but only in Iran and South China, and not in Pakistan or a Tethys-wide data set. In Iran and South China, Bray-Curtis dissimilarity values comparing occurrence frequencies between adjacent stages were elevated across the G-L transition, although other intervals exhibited similarly large shifts. However, genus occurrence frequencies were less strongly correlated or were anti-correlated across the G-L transition, suggesting moderate faunal turnover among dominant brachiopod genera. In contrast to previous inferences from silicified faunas, abundances of brachiopods, bivalves, and gastropods remained consistent from the Guadalupian to Lopingian in non-silicified local counts and global occurrences, implying that the brachiopod-mollusk shift did not occur until the end-Permian extinction. Ecological and taxonomic consequences were both minor in level-bottom settings, suggesting that severe environmental perturbations may not be necessary to explain biotic changes during the Guadalupian-Lopingian transition. | <urn:uuid:803d78a8-2e31-45da-a6dc-1def4a94d486> | CC-MAIN-2017-04 | http://paleobiol.geoscienceworld.org/content/41/2/266 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560281151.11/warc/CC-MAIN-20170116095121-00107-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.928134 | 424 | 2.84375 | 3 |
This is the story of the first miracle of Jesus. It has no parallel in the synoptics, and it stands quite alone giving insight into the way Jesus and His disciples lived that many Christians love to ignore: Jesus drank wine. (Horror!) Just for fun, compare this passage with Colossians 2:20 ff.
If this blows your mind, then let me quickly sum up this passage for you: Jesus performed His first miracle at Cana, where for the first time His glory and authority was revealed, and His disciples came to believe in Him. OK, faint of heart, see you tomorrow and have a great afternoon!
Those of you who can handle this, let’s have a closer look…
The scene is set: Jesus, His mother (John never says “Mary”) and the disciples were there. This seems to have been three days after the calling of Phillip. No reason is given for the reason the wine ran out. Some have postulated that the attendance of Jesus and the disciples was the cause, but since John says that they had been invited, this seems unlikely. It would also seem that Mary was well known to the family involved here, since she so quickly took charge of the disaster. When she brings this social catastrophe to Jesus’ attention, His reaction is interesting: literally, “What’s it to me?” Notice that Mary seems to be aware that Jesus can remedy the situation easily; why else would she pass right over His question and tell the servants to do whatever He says? Jesus statement that His time has not yet come has troubled some commentators who haven’t noticed that In John’s Gospel, John uses this wording to refer to the time of Jesus’ being glorified (by the cross) and not to His performance of miracles, in this case a rather mundane one, if indeed a miracle can ever be called that.
The total capacity of these jars would have been in the range of 120 to 180 gallons. It is worthy of note that Jesus used all of the jars and had them filled up completely; nobody could say that Jesus’ power was limited, nor could they claim that He just slipped some kind of magic fairy dust into them: they were full.
When the servants drew the “water” from the jars and served it to the master of the banquet, the master confirmed that not only was this wine, but it was the “good stuff”. It can be hilarious reading commentaries about these verses when the commentator goes on and on about how this was “obviously” not really wine but unfermented grape juice.
One of the cardinal rules of interpretation of the Bible is that you must set aside your pre-suppositions, opinions and traditions and let the text speak for itself. When you are confused or feel that you have come upon a contradiction, there are various things you can do to figure out what the meaning is. Here are two easy ideas: You can usually do a word study and find out what is going on. In addition, a close examination of the complete context will also aid in determining what the text is teaching. After this has been done, if the Bible turns out to support your pre-suppositions, opinions and traditions: Marvelous. But where it doesn’t, your presuppositions, opinions or traditions are wrong. In this case, if you are bound and determined to say that Jesus would never allow the serving of wine, you have two problems to deal with: First, the Greek word used here is oinos which happens to mean “wine”. The Greek word for grape juice is tnyx. Why would John, under the inspiration of the Holy Spirit, make such a writing error? Second, note what the master of the banquet said in verse 10. Does that even remotely indicate that they were dealing with grape juice? Does it sound to you like what he would say if the wine was watered down to less than 50% wine? A better question would be, “Was Jesus trying to get everyone drunk?” The text does not tell us that Jesus had everyone’s glass refilled, it tells us that the master of the banquet, the only one we know for sure that was aware of the problem got a sample. We don’t know what the other attendees did after that, or if they even became aware that the wine was gone. We do know why Jesus performed the miracle, however.
The brand new disciples, who had responded to the testimony of John the Baptist, and then to each other’s saw for the first time that Jesus was more than a man who had been blessed by God: He had a power that no mere mortal possessed, and they put their faith in Him. This would also be the reason for His future miracles; to confirm His true identity and the authority by which He taught.
Yes dear reader, this is the point, and all of the silly business of trying to explain away the wine only draws our attention away from the majesty of our Lord. | <urn:uuid:953788eb-543d-42a6-b394-552cb3e00bd7> | CC-MAIN-2022-33 | https://lifeprojectblog.com/2016/09/26/jesus-first-miracle-2/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882572833.78/warc/CC-MAIN-20220817001643-20220817031643-00273.warc.gz | en | 0.983091 | 1,046 | 1.867188 | 2 |
The Science of Layered Shots
Originally published September 6, 2010. Updated on 9/8/2021
Layering shots is not only a pretty way to pour delicious drinks, it's also a lot of fun.
A bit of flavor mixology, some math, some experimentation, pretty colors... that's always a recipe for entertainment!
It's a shame that it seems to be a technique that's gone out of favour - the fast paced environment of today's clubs has put a kibosh on the previous popularity of layering. Bah! Let's bring it back!
How to Make Layered Shots
There are a few bits of info you’ll need to know before layering shots. Here we go!
1. Understanding Specific Gravity
"Specific gravity" is a number representative of the density of a liquid. The lower the number, the less dense the liquid is.
A few examples:
Grenadine: 1.18 (Heavier than water)
Southern Comfort: 0.97 (Lighter than water)
Just search "Specific Gravity" along with the name of an alcohol, and you're bound to find the information you're looking for.
Write down the numbers of each alcohol you would like to play with, then arrange in order.
That is to say, the higher the alcohol content of a liquid, the lighter it is - and the lower the specific gravity reading will be.
Like all rules, there are some exceptions to this.
Also, cream-based liqueurs tend to be lighter than non-cream based liqueurs of the same ABV.
Again, there are some exceptions... experiment! It's all in the name of science, after all! 🙂
2. Equipment for Layered Shots
At the very minimum, you’ll need:
- Shot Glasses
- A teaspoon
However, I REALLY recommend getting some appropriate pour spouts, as they definitely make things easier!
This photo shows my favorite type of pour spouts for liqueur bottles. It's nice to have a bunch on hand, and they cost next to nothing:
The thing that I like about this spout is that you can slow the flow of the liquid by placing your finger over the hole on the top side - gives you a lot of control!
3. Pouring Technique for Layered Shots
In addition to layering in order of density, you need to slow the pour of your liquids, as to not disturb the surface of the layer before it.
There are several methods people use - pouring over the back of a spoon, pouring down the handle of a bar spoon, using a syringe, pouring over a cherry.
My own preference incorporates a favorite style of pourer with spoon technique - see pictures and description a bit further below!
4. Mixing flavors in a pleasing way.
Each of the flavors that are incorporated into an individual shot will hit the tastebuds in rapid succession - you'll want to pick flavors that go well together!
5. Choosing Colours
All that effort figuring out the liqueur densities will be wasted if you layer liquids with a similar appearance - so choose liqueurs with contrasting colours.
In addition to contrasting color, it can be really striking to layer clear liquids with cream-based liquids.
How to Layer Shots
So, now that you have the basic idea, let's get started!
Organize Your Alcohol
First, pick out a few liqueurs, spirits, and syrups (such as grenadine) in a variety of colors and ABV / Specific Gravity readings.
Arrange them in order of specific gravity, from the heaviest to the lightest.
Pour Your First Layer
Carefully pour your first layer, trying not to splash any on the inside of the glass, above where the top edge of the layer will be.
Pour Your Second Layer
Position a spoon into the shot glass as show in the photo below.
I know most places will tell you to pour it over the BACK (convex) side of a spoon, but ignore that. Pouring down the concave INSIDE of the spoon gives you more control, IMHO.
Pouring over the convex side of the spoon introduces the element of chaos - your pour can go anywhere.
With the inside of the spoon, the pour is funneled to where you want it to go - the tip.
Anyway, aim the spoon to be near - but not actually touching - the first layer of alcohol. The tip should touch the inside of the glass.
Keep the pour as slow as you can.
I only had a teeny bottle of Bailey's on hand for this photo - the small bottles like this are good for a slow, controlled pour.
Otherwise, use the type of pour spout mentioned above, manipulating the speed by covering/uncovering the hole.
Continue carefully pouring your liquid until you reach the desired amount.
Pour Subsequent Layers
This shot incorporated only 2 liqueurs - Creme de Menthe and Bailey's, but 3+ layer shots are awesome too.
Just divide up the height of the glass, eyeballing measurements as you go.
For a third - or subsequent - layer of liqueur, just repeat the above instructions, using a lighter liquid.
Pro Tips for Layering Shots
Chilling the ingredients changes the specific gravity readings.
Liquids become less dense as they warm, and more dense when chilled.
Feel free to play with this knowledge to make your desired creations work!
Give your spoon a quick rinse between layers if possible. Residue of previous layers can mess with your pour!
Time Can Heal Some Mistakes!
If you mess up when trickling a layer into your shot glass, carefully finish pouring it, and set it aside for a few minutes.
The layers should level out on their own.
Hell, if you're planning to serve a bunch of layered shots at a party or whatever, you can cheat a bit!
Pour them ahead of time, not bothering to be too fussy about getting the layers perfect.
Arrange the shot glasses on a platter and chill. They'll settle out by the time you serve them!
The photos below demonstrates what happens when you mess up a pour (banged the bottle off the lighting apparatus!):
This was over the course of about 2 minutes - given more time, it will have corrected to a sharp line, as if I hadn't screwed it up. It didn't last that long, though - it was tasty!
*Caveat - This is assuming that there is enough difference in specific gravity for them to level out.
If your shots didn’t layer because you used liqueurs of a similar specific gravity, they’re not going to level out.
Light It Up!
If you feel like adding some drama to your shot presentation, remember this:
Your highest ABV liqueur/spirit will be on top.
The higher the ABV, the more likely it'll BURN!
Feel free to light the top of your shots on fire!
Use a lighter - not a match - to carefully light the top of the liquid aflame.
Please observe basic fire safety common sense - hair tied back, no baggy clothes dangling into the flame, etc.
Also, be careful with the flame - sometimes the flame can be hard to see!
Layered Shot Recipes
Ready to go? Try these traditional shot recipes!
Note: All ingredients are listed in order of pour. The first ingredient mentioned is poured first, etc.
Creme De Menthe
Creme de Banane
Blue Eyed Blonde Shot
Creme de Banane
Green Eyed Blonde
Creme de Banane
Interested in boozy culinary fun? You should check out my first cookbook, The Spirited Baker. It’s FULL of fun, tasty recipes using spirits and liqueurs for flavour – you should check it out:
Combining liqueurs with more traditional baking ingredients can yield spectacular results.Try Mango Mojito Upside Down Cake, Candy Apple Flan, Jalapeno Beer Peanut Brittle, Lynchburg Lemonade Cupcakes, Pina Colada Rum Cake, Strawberry Daiquiri Chiffon Pie, and so much more.
To further add to your creative possibilities, the first chapter teaches how to infuse spirits to make both basic and cream liqueurs, as well as home made flavor extracts! This book contains over 160 easy to make recipes, with variation suggestions to help create hundreds more! Order your hard copy here on my website, through Amazon, or through any major bookseller.
More Cocktail Recipes
Looking for more ideas for cocktail hour? We've some recipes for you!
Birthday Cake Martini
Boozy Fun With Fresh Citrus
Boozy Sparkling Cider Float
Candied Rims for Cocktails
Candy Apple Martini Recipe
Candy Cane Martini
"Drinking in LA" Cocktail
Fresh Peach Daiquiri Recipe
Fuzzy Peach Candy Cocktail
Grown-up Hot Chocolate & Hot Cocoa
Halloween Themed Shooters
Homemade Clamato & Bloody Caesars
Homemade Wine Slush Mix
Jolly Rancher Martinis
Marie's Favourite Mojito
Rum Runners Cocktail Recipe
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Well, the published nonsense, anyway! | <urn:uuid:83182a14-f214-454f-b7e9-edf369fd4970> | CC-MAIN-2022-33 | https://celebrationgeneration.com/the-science-of-layered-shots | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570977.50/warc/CC-MAIN-20220809124724-20220809154724-00469.warc.gz | en | 0.877771 | 2,083 | 1.773438 | 2 |
Narrow Your Investigation To Make Informed Decisions?All | Demographics | Education | Geography | Economic | Housing | Government | Taxes | Weather | Crime
People run the government through election of representatives and officials. Local governments are important to provide cohesion between individuals who must share public places. Worthwhile laws need to be debated, passed, and then enforced for a community to remain viable. Communities such as zip code 32169 are often affected in positive and negative ways by government performance.
Address: 2810 S Atlantic Ave, New Smyrna Beach, Florida 32169
Ownership: For Profit - Corporation
Number of Residents: 138
Percent Occupied: 71%
Name: Crystal River
Address: 15760 West Power Line Street; Crystal River, FL 34428-6708
Distance: 105 Miles
|Retired Workers:|| 2,310 |
|Disabled Workers:|| 170 |
|Widowers Workers:|| 275 |
|Spouses Workers:|| 170 |
|Children Workers:|| 55 |
Do you want to research zip code 32169? If you are considering a move, want to view where your friends live,
or just discovering a new place to travel, our data will interest you!
Use any data on this web site at your own risk. citymelt.com does not warrant or certify the correctness of data. | <urn:uuid:2991a188-e75d-4109-b05f-9749c89bad58> | CC-MAIN-2017-04 | http://www.citymelt.com/zip/Florida/32169-FL/government.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280825.87/warc/CC-MAIN-20170116095120-00210-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.858364 | 283 | 1.703125 | 2 |
Sounds of the River: A Memoir (Hardcover)
"A story about suppression, humiliation, vindication, and, ultimately, triumph." —New York Times Book Review
From the bestselling author of Colors of the Mountain—an engrossing, gloriously written coming-of-age saga that picks up where that book left off—in Beijing during China’s Cultural Revolution
In this "equally beguiling sequel to his acclaimed memoir" (Kirkus Reviews), teenager Da Chen takes his first train ride away from the farm he was raised on to his new university life in Beijing. He soon faces a host of ghastly challenges, including poor living conditions, lack of food, and suicidal roommates. Undaunted by these hurdles, and armed with a dogged determination to learn English and "all things Western," he competes to win a chance to study in America—a chance that rests in the shrewd and corrupt hands of the almighty professors.
Poetic, hilarious, and heartbreaking, Sounds of the River is a gloriously written coming-of-age saga that chronicles a remarkable journey—a travelogue of the heart.
Da Chen is the author of Colors of the Mountain, a New York Times bestseller; Sounds of the River: A Young Man's University Days in Beijing; Brother; and two books for children, Wandering Warrior and China's Son: Growing Up in the Cultural Revolution. He grew up in China during the Cultural Revolution and now lives in New York.
Readers will already be looking forward to the next installment. — Kirkus (Starred Review)
“Da Chen’s voice comes from the soil of China...his exuberance for life and its possibilities set him apart from others in the genre.” — Los Angeles Times
Da...is certainly likable. And his transformation from country boy to big city college professor moves briskly and entertainingly along. — San Francisco Chronicle Book Review
“A story about suppression, humiliation, vindication and, ultimately, triumph.” — New York Times Book Review
“Da Chen’s latest book confirms that he is an extraordinary individual. Chen’s immigrant success story is exceptional, for he has realized the American Dream in all its glory.” — USA Today
“What makes this vivid coming-of-age story so worthy is not so much the lively and amusing anecdotes...but a bracingly wry self-awarness that gives traction to a story that could be clyoign but is instead funny, exciting, and moving.” — New York magazine | <urn:uuid:282489de-ee02-424e-a29b-9515857c72aa> | CC-MAIN-2022-33 | https://www.countrybookshelf.com/book/9780060199258 | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571222.74/warc/CC-MAIN-20220810222056-20220811012056-00668.warc.gz | en | 0.928574 | 540 | 1.617188 | 2 |
Crews Look Toward Containment For Palmer Fire, Using ‘Ping Pong Balls’ To Fight Fire With Fire
-Red Cross Contact: 509-670-5331
–Public Info Meeting, Aug. 25, 6 p.m. Watch here.
Fire managers think they’ll get the Palmer Fire in north-central Washington under control this week. So far, the fire has burned more than 18,000 acres and has burned more than 30 structures.
Crews have fought fire with fire to help secure the containment lines. One method you may not have heard of uses ping pong balls and helicopters. They’re officially called PSDs, or plastic spherical devices.
The ping pong balls have an accelerant inside. Different types ignite faster than others. It all depends on the terrain and type of burn they want. For example, slow burns allow for larger trees to not be damaged, but they burn fuels on the ground. The type of accelerant and amount of ping pong balls regulate how hot the fire burns.
Public information officer Doug Epperson says the ping pong balls are used to cover a wider area than what handcrews do.
“It actually comes out of a hopper, like when you see somebody play bingo. There’s a bunch of balls in there,” Epperson said.
Burning wider areas helps crews not have to worry about spot fires after they leave, especially in windy conditions, Epperson said.
A cold front blew into north-central Washington on Monday, bringing with it wind gusts of 20 mph.
Fire crews worked Monday to cut down hazard snag trees on the fire’s western edge. Falling snags are very dangerous to fire crews. The sawyers are clearing the snags before crews can go in and search for hotspots.
Crews also worked Monday to put a 300-foot radius around each structure to help protect them going forward.
Over the past weekend, the fire managers worked with ranchers to protect grazing allotments, Epperson said. He said they saved more than 200 acres of grazing land by using various techniques, like burning different areas or finding natural barriers for containment lines.
“There’s only so much land up here,” Epperson said.
Officials are asking people not to drive on closed roads. Epperson said they’ve seen a lot of people passing road closures. While there may no longer be flames in the area, he said there is a lot of heavy equipment in use. Firefighters are also using the roads to travel.
Managers are planning a virtual public meeting Tuesday, Aug. 25, at 6 p.m. They plan to update people on the status of the fire and take questions over Facebook Live from Okanogan County Emergency Management. People can submit questions in advance to [email protected].
At around 18,000 members, the Okanogan Highlands Fire Watch group continues to provide what members call valuable and lifesaving information. People post evacuation notices, fire maps and recovery resources throughout fire season. Daniel Pratt started the group in 2015 during another particularly bad fire season for Okanogan County. Continue Reading Eastern Washington Residents Praise Facebook Group For Connections During Trying Fire Seasons
A dry cold front is expected to push into central and eastern Washington this weekend, bringing with it lots of wind from the north. That could fan the flames of fires, especially new starts that are just taking off. Winds could reach 15 to 25 miles per hour, with gusts around 40 miles per hour. Continue Reading Windy, Dry Weekend Ups Wildfire Potential, As Crews Watch How Palmer Fire Lines Will Fare
Crews have fought fire with fire to help secure the containment lines. One method you may not have heard of uses ping pong balls and helicopters. They’re officially called PSDs, or plastic spherical devices. Continue Reading Crews Look Toward Containment For Palmer Fire, Using ‘Ping Pong Balls’ To Fight Fire With Fire | <urn:uuid:482c0775-cd76-4155-8272-8041515b0367> | CC-MAIN-2022-33 | https://www.nwpb.org/2020/08/24/fire-crews-get-upper-hand-in-okanogan-county-using-ping-pong-balls-to-fight-fire-with-fire/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882570879.1/warc/CC-MAIN-20220808213349-20220809003349-00470.warc.gz | en | 0.931362 | 849 | 2.15625 | 2 |
Although a copy of a 17 January mono mix had been sent to Capitol Records for release and radio distribution, Paul McCartney felt that it could be improved upon. Three more mono mixes, numbered 12-14, were therefore made on this day, the main difference being the omission of the seven-note trumpet coda by David Mason.
The mixing session began at 6.30pm and lasted for two hours, taking place in the control room of Studio One. From 9-10pm tape copies of remix mono 14 were made, and discs were hastily pressed and sent to the United States.
Also on this day...
- 2014: The Beatles win lifetime achievement award at the Grammys
- 1969: Get Back/Let It Be sessions: day 14
- 1968: Pattie Harrison models for Ossie Clark
- 1968: The Beatles film their Yellow Submarine appearance
- 1965: John and Cynthia Lennon holiday in the Swiss Alps
- 1964: Live: Olympia Theatre, Paris
- 1963: Live: Co-operative Hall, Darwen
- 1961: Live: Hambleton Hall, Liverpool
Want more? Visit the Beatles history section. | <urn:uuid:a1903ee2-9026-488c-817b-43405afae9f2> | CC-MAIN-2016-44 | https://www.beatlesbible.com/1967/01/25/mixing-penny-lane/ | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988720380.80/warc/CC-MAIN-20161020183840-00054-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.927527 | 234 | 1.828125 | 2 |
A series of reports at Prachatai and at the Bangkok Post are a useful reminder of what Thailand is like when the military is in charge.
Corruption, the use of special powers, thuggery, working with business people to exploit the poor in coercive ways. And, impunity. The military and the bureaucrats can do whatever they want, and get away with murder, abduction, enforced disappearance and other gang-like bad behavior because, like a male street dog licking its undercarriage, they can.
We apologize for this rather rude analogy but the actions of the military and the junta are uncivil, uncouth and brutish.
The first story at Prachatai relates to three suspects – red shirts, of course – arrested, tortured, kept in jail longer than the law allowed and accused of accused of “carrying out an attack with explosives on the PDRC protest in Trat on 22 February 2014, which resulted in the deaths of three people, two of them children, and 39 injured.” They were acquitted by the Provincial Court in Trat. The evidence was non-existent and the military thugs who arrested them didn’t even bother to appear in court.
The second Prachatai story is one that seems a remarkably 20th century account of primitive accumulation. Investors, in cooperation with the authorities sent hired thugs to attack a rural community the tycoons want moved (in many previous cases the thugs have usually military men out of uniform). In this case, “a group of men with military and police officers came to the beach and surrounded the area, which the investors have been attempting to use for developing lucrative projects for years.” The local community was attacked and beaten when they objected to the tycoons taking their community and land.
The first Bangkok Post story is about the use of Article 44 to progress business interests at the expense of local communities, mainly in border areas, including coal-fired power stations. The idea is to prevent local communities complaining.
The last story is an op-ed by Sanitsuda Ekachai, with a title that sums up everything in the four stories: “Poor suffer as regime goes back to old ways.” Land “reform,” small-scale fishers, farming communities being pushed about by miners, and more, all supported by the political and economic bosses and their hired thugs. As one activist described it: “Our country is going backward in time, not years, but decades…”.
Update: On the second Prachatai story above, of course, there is no evidence that the company that had men beat the “sea gypsies” with sticks were linked to the local military mafia. A story in the Bangkok Post refers to a leaked document on social media showing the Baron World Trade Co asked brass at the Royal Thai Army Military Circle 41 base in Nakhon Si Thammarat to deploy troops to protect company staff during construction work.” Racism, accumulation and corrupt links between military and business are linked in this case. | <urn:uuid:81b689f9-1257-4663-98ac-8e6a43babd5d> | CC-MAIN-2017-04 | https://thaipoliticalprisoners.wordpress.com/2016/01/27/41675/ | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560285289.45/warc/CC-MAIN-20170116095125-00147-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.967979 | 632 | 1.671875 | 2 |
Wild rabbits exist right across the United States in rural areas and on the bordering grass and woodlands near suburbia. All rabbits are herbivores, eating only plant material, and the greater part of their diet is grass and hay, accompanied by large amounts of fresh water. Wild rabbits eat mostly wild grasses and naturally dried hay or dried grass. In the winter months grass can become scarce, and wild rabbits eat bark and twigs and can venture into gardens and parks in search of food.
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Rabbits have a very delicate digestive system requiring a balance of good bacteria, and their diet is imperative to a healthy digestive system. Long fibres such as are found in hay and grass are necessary for a rabbit's digestive tract, and that's why they eat so much grass and hay. Supplying piles of alfalfa hay that is high in calcium provides a natural source of fibre and nutrition for wild rabbits in winter and will also deter them from eating other plants in your garden.
During winter months leave the lawns slightly long, as this will provide natural feed for the wild rabbits, and even if the grass dies off they will consume it as hay. Plant lawn grasses that are hardy in winter months and do not die back easily due to frost to ensure there is grass all year round. The dying back of native grasses is the cause of food shortage in winter for wild rabbits.
Planting low shrubs in patches or rows around the garden and on the edge of parks provides shelter and protection for the wild rabbits on the move. Leaving piles of leaf litter and twigs can also provides additional food and a place to shelter from predators while feeding. Wild rabbits will sometimes make a burrow under permanent wood piles.
Alfalfa hay pellets which contain seeds are the best food pellets for wild rabbits as they are a concentrated food source. You do not want wild rabbits to become dependent on your supply of food pellets, and they may also attract rodents, but in winter when other food supply is scarce they are most welcomed by the wild rabbits.
Wild rabbits will eats any green vegetables that you have in your garden if they are short of food in winter, and because only a small percentage of a rabbit's diet is diversified, it is not good for them to eat large amounts of green vegetables. You should put your vegetables in wire enclosures to deter wild rabbits from feeding there and have a supply of hay available close by as a healthier alternative.
- 20 of the funniest online reviews ever
- 14 Biggest lies people tell in online dating sites
- Hilarious things Google thinks you're trying to search for | <urn:uuid:40de8c66-2bbd-40d3-9b22-59d773a698e6> | CC-MAIN-2017-04 | http://www.ehow.co.uk/info_8698470_feed-rabbits-wild-during-winter.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560280763.38/warc/CC-MAIN-20170116095120-00522-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.954281 | 540 | 3.4375 | 3 |
In the never-ending battle against aging, it seems like there’s always a new frontier to conquer. Case in point, your hair. Where once we thought spackling grey roots with dye would do the trick, it turns out that’s just scratching the surface. Aging can cause hair to become brittle, dry and less dense.
“Just like with skin, everyone ages differently,” says Paul Schiraldi of L’Oréal Professionnel. “It usually begins around the age of 35. We’ve found that there’s a 10 to 20 percent loss of density in individual strands over each progressive decade.”
What’s more, says stylist Frédéric Fekkai, one’s chronological age doesn’t necessarily correspond with the age of your hair. “There are a lot more people using color and chemical services at a younger age,” he says, “as well as a lot more [environmental] pollution, which all contribute to aging hair.”
But with knowledge comes power and as technology has advanced, so have the treatments. Phyto and L’Oréal have new regimens that focus on redensifying thinning hair, while Logics addresses replenishing dry, damaged hair and maintaining color.
Jonathan Antin’s new Ionic Balance Technology shampoo and conditioner tackle breakage with a blend of tourmaline and amethyst ionic crystals, said to make hair more manageable and soft.
“The ingredients are key,” says Antin. “They’re packed with the highest level of antioxidants, which are just as beneficial to the hair as they are to the skin.” | <urn:uuid:c6ce193c-84b4-43c7-821f-60312523a9f4> | CC-MAIN-2016-44 | http://wwd.com/beauty-industry-news/hair/dense-matter-1510342/print-preview/ | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988717783.68/warc/CC-MAIN-20161020183837-00076-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.946354 | 365 | 1.929688 | 2 |
I chose this event since this time in history was a turning point in America. Prior to President Abraham Lincoln signing the Emancipation Proclamation on September 22, 1862, slavery was a huge trade in the United States. But Abraham Lincoln’s main goal was to unite both halves of the Union. Since the entire purpose of fighting the Civil War was to unite both sides of the Union, President Lincoln made statements in August of 1862 that if he did not have to end slavery in order to end the Civil War that he would not have. During that time, many people considered President Lincoln’s statement to be disingenuous, given that Lincoln had long been a vocal opponent of slavery. As early as 1849, Abraham Lincoln believed that slaves should be emancipated, advocating a program in which they would be freed slowly over time. Early in his presidency Lincoln still believed that gradual emancipation was best way to go and he tried to win over legislators. In an attempt to gain support, he proposed that slaveowners be compensated for giving up their “property.”
“Abraham Lincoln Civil War and Emancipation”Get custom essay
But he did not receive the support he anticipated. The Civil War resulted in many short term effects. The union came together and solidified under the leadership of President Abraham Lincoln. As a result of the North winning the war, this led to the creation and enaction of the Emancipation Proclamation that freed the slaves of the south that had succeeded from the union. This began creating equality and civil rights for all people during the movement. Although, the Emancipation Proclamation did not guarantee the rights of slaves to have the same privileges as the whites, it began the process of moving in that direction. It also led to the creation of allowing women to have the same rights as men. In September of 1862, after the Union’s victory at Antietam, President Lincoln issued a preliminary notice stating that, unless the rebellious states returned to the Union by January 1st, he would grant freedom to slaves within the states. The notice also left room for a plan of compensated emancipation. None of the Confederate states took President Lincoln up on the offer, and therefore on January 1st he presented the Emancipation Proclamation.
The proclamation declared that, that all persons held as slaves within the rebellious states are, and henceforward shall be free. The Emancipation Proclamation did not free all slaves in the United States but rather it declared only those slaves living in states not under Union control. President Lincoln’s Secretary of State, William Seward, stated, “We show our sympathy with slavery by emancipating slaves where we cannot reach them and holding them in bondage where we can set them free.” Lincoln was fully aware of the irony, but he did not want to antagonize the slave states loyal to the Union by setting their slaves free. The proclamation also allowed black soldiers to fight for the Union where soldiers were desperately needed. This is what tied the war and slavery together.
There were many long term effects resulting from the end of the Civil War. Not only did it abolish slavery, it also was the first building blocks of rights for African Americans who were former slaves and started the industrialization movement. By ending slavery, this caused a problem for farmers and ranchers in the south. The farm owners no longer had slaves to work on their farms and had great difficulty finding labor to assist with daily tasks. Therefore, the farmers began to see a decline in farming and had to turn towards industrialization. Manufacturing industries and businesses were created and caused a population movement so that people could be closer to jobs and were able to find work. The North was actively growing their industries and towns, but the South struggled to flourish. The South had many cities which were damaged as a result of the war and were having to rebuild. The south also relied heavily on the agriculture industry but had difficulty sustaining the land after the war damaged the crops and the labor left after slaves were freed. The end of the civil war and the signing of the Emancipation Proclamation created multiple amendments to the US Constitution in the upcoming years which furthered the rights of African Americans. Overall, the Civil War impacted many people from your every day farmer to your daily business man to the newly freed slaves.
The results of the Civil War forever changed the shape of the United States as we know it today. The end of the Civil War and the signing of the Emancipation Proclamation not only brought freedom to the slaves, but also began years of civil rights movements which ultimately guaranteed that African Americans could become citizens of the United States and attain citizenship. Civil Rights movements in coming years also provided African Americans the right to vote and ended the segregation of whites and blacks. If the outcome was to end differently, I would think that the south would push to further expand slavery though the north. Slavery may have remained in effect for many years longer, but I do believe that it would have eventually ended. By delaying the end of slavery, the rest of history would also be delayed in terms of the civil rights movements.
Abraham Lincoln Civil War and Emancipation. (2019, Jul 08).
Retrieved August 19, 2022 , from
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JERUSALEM (Feb. 3)
For the second successive week the Israel Cabinet devoted an entire session to the country’s economic problems. Also, as occurred last week, the Cabinet met in a separate session to discuss other matters, including preparations for the negotiations with the Germans and current developments in the Middle East as well as specific Israel-Arab relations.
Speaking before a group of representatives from kibbutzim from all parts of the country, Finance Minister Eliezer Kaplan today warned of the dangers confronting the Israeli economy and the state itself if it cannot reach economic independence, which he defined as the ability to produce all that it needs.
He asserted that in order for the country to achieve economic independence within the next eight to ten years, special efforts must be made to attract capital investments, credits must be controlled, wages must be tied to production and the standard of living must be lowered.
Meanwhile, the price of bread rose eight percent this week-end and white flour went up five percent as a result of the withdrawal of a portion of the government bread and flour subsidy. The new prices will also reflect increased labor costs and profits. | <urn:uuid:6fc71d92-5637-4c5e-8f77-ec2c348cf21e> | CC-MAIN-2016-44 | http://www.jta.org/1952/02/04/archive/israel-cabinet-discusses-economic-situation-kaplan-sounds-warning | s3://commoncrawl/crawl-data/CC-MAIN-2016-44/segments/1476988721278.88/warc/CC-MAIN-20161020183841-00147-ip-10-171-6-4.ec2.internal.warc.gz | en | 0.95272 | 235 | 1.585938 | 2 |
Many Microsoft Edge users are missing out by not using Microsoft Edge favorites. Why you should be using favorites when surfing the internet? Basically: because it will save you time. Let’s say you’re on a certain page that contains a great deal of information on a topic that interests you or a unique insight on a project you’re working on but you don’t have the time to read the entire thing right away. Then you may want to save that page for later reference. Working with favorites is exactly about that: saving certain webpages that interest you for later reference.
Have you ever looked at something cool or interesting on the internet and a couple of days later you wanted to show that to someone else only to discover that you weren’t able to find the darn thing back? I can tell you: it happens to me too. And I do use Microsoft Edge favorites.
Ok, that last observation merely illustrates that, even if you know how to use favorites, you still may find yourself in a situation where you simply thought it wasn’t necessary to put that particular web page in your favorites and a while later you wish you had because you can’t find it back. But that’s just human psychology I guess ...
With that out of the way, let’s take a look at how you can quickly master Microsoft Edge favorites. (Yes, you can see I'm slowly getting close to the REAL point of this piece :-)
When you’re looking at a certain web page in Edge and you want to add that page to your favorites, simply click on the star-shaped "favorites" button near the top right corner of the window. You can do this right now, with the page you’re reading at this very instant so you can see how it works.
Clicking the favorites button will open the Microsoft Edge favorites menu, where you can make a few more choices before you actually save the page in your favorites.
The field “Name” usually comes with a pre-filled suggestion, which can be altered. Once you start working with Microsoft Edge favorites, you’ll quickly notice that these suggestions are not always meaningful (often very long and confusing), so I would suggest that you always enter a convenient name when saving favorites.
The “Save location” dropdown list (see image above) allows you to either save the web page in your general favorites folder or on the favorites bar. In this example I’ll select the favorites bar, so I can turn that on and show you how it works.
As you can see in the image just above, you can also create a new folder within the favorites group or on the favorites bar and place it in there.
With the steps above you save a web page in your Microsoft Edge favorites bar, but you might have to enable the favorites bar before you can actually see it. In order to do so, click on the three dots in the top right hand corner and select settings.
One of the first options in the settings screen is “Show the favorites bar” so make sure to flip that switch to the “on” position.
You’ll immediately notice that the favorites bar appears in your Microsoft Edge window and your freshly added link is sitting there (By the way: the name you see there is the name you entered when adding the favorite, so here's another reason why you don't want any long, meaningless strings of text there).
So let’s create another one on your favorites bar just to see how that looks.
After repeating the steps described above your Microsoft favorites bar might look similar to this.
If you have several links sitting in your Microsoft Edge favorites bar, you can rearrange them in a different order if you like, by clicking and dragging them to a new position.
Putting your favorites like that on your favorites bar can be very convenient to go to your favorite websites with one single click, but the space on the favorites bar is limited so you might soon find yourself wondering: how do I delete items from the Microsoft Edge favorites bar? The answer is very simple: right click the item and select delete from the menu.
Or you can start saving favorites in the general favorites group if your favorites bar becomes too cluttered.
To save links in your general favorites folder or group, simply click the favorites icon just the same as in the previously described steps and then select “Favorites” in the drop down list before you click the “Add” button.
If you want to use one of your saved favorites later on, click on the Microsoft Edge “hub” icon (see image below) and your favorites will be visible right there.
Again, to remove items from this list, right click with your mouse and select remove.
When saving a web page in your favorites, you can also use the “Create new folder” link in order to create folders to organize your favorites.
Microsoft Edge will prompt you for a folder name so you can group related stuff together. With folders, just like anything else, you can right-click and rename or remove the folder if you no longer need it hanging around.
Some people prefer to have their favorites window to be open permanently. You can easily get that by clicking on the “hub” button in Microsoft Edge and then clicking on the pin icon, like illustrated in the image below.
To close the favorites window again, simply click the “x” icon on the top right corner of the favorites window.
This Microsoft Edge favorites guide is part of a series of Microsoft Edge tutorial articles in my computer tips and tricks section, so feel free to check out the other parts as well. If you enjoyed it, please leave a comment below, I’d appreciate it very much, thanks! | <urn:uuid:e06e86a1-49c9-4074-ae49-ec362b813e9d> | CC-MAIN-2017-04 | http://www.tipsdotcom.com/microsoft-edge-favorites.html | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560285289.45/warc/CC-MAIN-20170116095125-00143-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.902224 | 1,208 | 1.820313 | 2 |
be out of line(redirected from be out of his line)
be out of line
1. Literally, to not be correctly positioned in a line with other people or things. Adjust that frame on the left—it's out of line with the other pictures on the wall. I was only out of line for a minute! Can't you let me back in?
2. To act in an inappropriate or unacceptable way. That reporter was out of line when he asked questions about my personal life. I'm sorry about last night, I was out of line when I made those demands.
3. To be inconsistent (with something else). That car service's exorbitant rates are out of line with others in the industry.
4. To be outside of one's skills or interests. In this usage, a noun or pronoun is used between "in" and "line." My brother is really studious, so sports are out of his line, as they interfere with his studying.
Farlex Dictionary of Idioms. © 2022 Farlex, Inc, all rights reserved. | <urn:uuid:6b1435f4-e023-4711-be4d-39682bd243de> | CC-MAIN-2022-33 | https://idioms.thefreedictionary.com/be+out+of+his+line | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882571584.72/warc/CC-MAIN-20220812045352-20220812075352-00668.warc.gz | en | 0.974448 | 224 | 2.484375 | 2 |
It was nearly twelve years ago when I sat before my then pastor in pre-cana counseling and was told “how nice it is that you are trying to help women by working in a domestic violence shelter, but now that you are going to be married your role is to be a wife and mother. Working outside the home will no longer fit into your life. Your duty is to have children and care for your family.”
Our conversation continued and according to my pastor, God was not concerned with what I had to offer my community, but rather with how many children I could bear and raise as Catholic. In that moment, I was told that my life and my efforts were of little value and that having children was the one thing I could do as a woman that would make my life worthy. How funny – or sad – that in the 21st century, women’s worth continues to be tied to her womb and all other efforts are not valued.
Just this last week Pew Research released a report stating that 4 in 10 households have mothers who are either the main or sole breadwinners for the family. With today’s economy most families need two incomes to stay afloat and thus 75% of mothers are working outside of the home. Whether moms want to or not, they are pulling double duty and rather than being praised they are judged as not caring enough about their children (or God’s wishes) to stay home and do what women are “supposed” to do.
Reacting to this study, Lou Dobbs and an ALL MALE panel on Fox News argued that working mothers are selfish and claimed they are destroying the natural order. Stating that “there is something terribly wrong in American society,” that children are being hurt, and that there will be a negative impact on generations to come, the panel opined that anyone who supports the idea of a working mom is going against “biology.”
According to panelist Erick Erickson, “When you look at biology, look at the natural world, the roles of a male and a female in society, and other animals, the male typically is the dominant role. The female, it’s not antithesis, or it’s not competing, it’s a complementary role. We as people in a smart society have lost the ability to have complementary relationships in nuclear families, and it’s tearing us apart.”
How interesting that there was no working mother on the panel to respond to these ridiculous claims. Although the Fox News panel argued that society is “dissolving” because mothers are working outside of the home, study after study has demonstrated that exclusive maternal care is not related to better or worse outcomes for children. For instance, the National Institute of Child Health and Human Development did a study from 1991-2006 where it tracked 1000 children over a 15 year span and concluded that working moms vs. stay at home moms did not impact cognitive, language, or social skills and also did not impact the quality of the mother child bond.
First let me say loud and clear, I am in no way discrediting the work and role of stay at home mothers. To use the phrase “working mother” is an oxymoron for sure. Mothers who choose to stay home and raise their children deserve to be recognized and praised as all mothers do. I will never engage in the “mommy wars” and argue for working mom over stay at home mom or vice versa. However, what I will argue for is women’s ability to make choices about motherhood and those choices should be respected.
To use religion or science to shame women for making incredible sacrifices to support their children is unforgivable. While I certainly acknowledge that fathers also face work-family issues, there is a clear difference between expectations of mothers and fathers. We do not use religion or science to claim fathers must work outside the home. Nor do we use religion or science to deny a father’s efforts to care for his family. In fact, discussions like those presented on Fox News do not occur about working fathers. Yet, it seems reasonable and appropriate to hold panel discussions about gendered topics that do not directly relate to any of the panelists.
Calling working mothers selfish, claiming that women’s contributions outside of the home are worthless, and declaring God only concerned with baby making abilities is outrageous. Stay at home mothers and mothers who work outside the home both make incredible sacrifices for their families. Why is our society so concerned with passing judgment, shaming, and tearing down? Why not acknowledge these efforts? Why not focus on creating opportunities so mothers have choices? It seems to me that women – and particularly mothers – continue to be the one acceptable target for discrimination. Sad but true.
Gina Messina-Dysert, Ph.D. is a Feminist theologian, ethicist, and activist. She is Director of the Center for Women’s Interdisciplinary Research and Education at Claremont Graduate University, Visiting Assistant Professor of Theological Ethics at Loyola Marymount University, and Co-founder of Feminism and Religion. Gina has authored multiple articles and the forthcoming book Rape Culture and Spiritual Violence. She is co-editor (with Rosemary Radford Ruether) of the forthcoming anthology, Feminism and Religion in the 21st Century and is a contributor to the Rock and Theology project sponsored by the Liturgical Press. Her research interests are theologically and ethically driven, involve a feminist and interdisciplinary approach, and are influenced by her activist roots and experience working with survivors of rape and domestic violence. Gina can be followed on Twitter @FemTheologian and her website can be accessed at http://ginamessinadysert.com. | <urn:uuid:ec80ae81-5e50-4bdf-ae77-91de8fccde4b> | CC-MAIN-2022-33 | https://feminismandreligion.com/2013/06/05/selfish-working-mothers-destroying-the-natural-order-by-gina-messina-dysert/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573623.4/warc/CC-MAIN-20220819035957-20220819065957-00679.warc.gz | en | 0.973814 | 1,189 | 1.59375 | 2 |
Confidentiality and HIV/AIDS: The case of Norma
Norma is a 21 years old college student who immigrated to the United States with her parents from El Salvador when she was 2 years old. She is bicultural in the sense proudly identifies herself as a Latina while at the same time having learned the instrumental behaviors that allow her to be effective and successful in the host culture. She speaks English and has been able to advance educationally to the point that she will soon graduate with a bachelor's degree. Socially, she interacts with people from different cultures.
Two years ago Norma started dating a young Latino man about her age, named Javier. They became close very quickly and started spending a lot of time together. Even though she is aware of the need for protection, they have had sex repeatedly without safety precautions. Javier refuses to engage in safe sex, and Norma has not been able to assert herself in this situation. Although he never went to college, Javier finished high school and was able to keep a job for a while. He was fired when he stopped going to work regularly. About a year ago Norma learned through common friends that Javier has been engaging antisocial behavior such as dealing drugs and joining groups that commit acts of violence. She has been also been the victim of his violent and abusive behavior. Because of his behavior, Norma has been slowly separating herself from Javier, which makes him even angrier. Last semester she attended workshop about HIV and realized that she could be at great risk, so was tested for the virus. To her extreme shop, she found out that she was HIV positive; she became so disturbed that she started seeing a counselor at the university. Norma thinks that Javier may have transmitted this disease to her, but she is not entirely sure as she had sexual relations with other people before Javier (sometimes unprotected).
Soon the counselor realized that she had an ethical dilemma because Norma has not disclosed her condition to Javier, even though she did inform her other partners. Informing Javier would allow him to make a decision about seeking testing and treatment if necessary. The counselor wonders whether she has the duty to warn Javier about the danger about being infected with the HIV virus. The counselor shared with Norma that she may have to disclose Norma's condition to Javier, under her duty to warn, unless Norma agreed to do it herself. Norma replies fearfully that if such information is disclosed to Javier she will be in imminent danger of being attacked by him to the point of fearing for her life. This belief is consistent with the history of Javier's violent behavior as reported by Norma. The counselor realized that this ethical dilemma has suddenly become more complex.
1. Discuss two key confidentiality issues from this case study . Explain why you think these issues are critical elements in a counseling practice. Then, analyze two challenges a counselor could face as he/she adhere to these elements of day-to-day practice. Conclude with an explanation of how you would address these challenges, including which decision-making model guided your decisions.
Two key confidential issues from this case based on ACA Ethical Standards
Under Section B: "Confidentiality, privileged communication and privacy", two key confidential issues based on ACA Ethical standards relate to this case.
(1) Standard B.1.d. (Explanations of Limitations) states:
At initiation and throughout the counseling process, counselors inform clients of the limitations of confidentiality and seek to identify foreseeable situations in which confidentiality must be breached."
(2) Standard B.2.b (Contagious Life-threatening diseases) states:
When clients disclose that they have a disease commonly known to be both communicable and life threatening, counselors may be justified in disclosing information to identifiable third parties, if they are known to be at demonstrable and high risk of contracting the disease. Prior to making a disclosure, counselors confirm that there is such a diagnosis and assess the intent of clients to inform the third parties about their disease or to engage in any behaviors that may be harmful to an identifiable third party.
? Explain why you think these issues are critical elements in a counseling practice.
Relative to ACA Standard B.l.d, it is critical to ...
This solution discusses two key confidential issues from a case study in relation to ACA ethical standards. | <urn:uuid:3e0bd307-b2dd-432d-ab98-3728a994a447> | CC-MAIN-2017-04 | https://brainmass.com/psychology/social-psychology/case-study-hiv-aids-410048 | s3://commoncrawl/crawl-data/CC-MAIN-2017-04/segments/1484560284405.58/warc/CC-MAIN-20170116095124-00036-ip-10-171-10-70.ec2.internal.warc.gz | en | 0.975478 | 881 | 2.0625 | 2 |
In her newest children’s book, her 66th, Nancy Carlson writes and draws with humor about coping with humiliation.
It’s a feeling she’s come to know all too well.
Minnesota’s most prolific and beloved picture-book author is about to declare personal bankruptcy. She hasn’t had a bank account since the IRS seized hers a few years ago. She dodges old friends to whom she owes money.
That’s not the worst of it.
“I’m lonely. I lost the person I talk to everything about,” said Carlson. “We were such a good team for such a long time.”
Carlson’s husband, Barry McCool, is in a Hopkins nursing home, living out his days in confusion.
Three years ago, at age 61, he was diagnosed with frontotemporal degeneration (FTD), a form of early dementia that causes profound personality changes. By the time McCool was diagnosed, the couple’s finances — and the life they had built together — were in shambles.
Instead of enjoying her legacy, Carlson is struggling to rebuild her life — and to do what she can to help others in the same situation.
“I want to talk about this so people can catch it before their loved one destroys their life, like Barry did,” Carlson said. “If I had only known, I could have stepped in so much sooner and could have saved us this awfulness.”
Carlson, 61, does have a legacy. With more than 4 million books in print, “she’s proven her staying power,” said Holly Weinkauf, owner of the Red Balloon Bookshop in St. Paul. “Just this morning, a mom with two little ones was here for story hour and bought a few Nancy Carlson books. She said they had been her favorites when she was a kid.”
Whether she’s tackling tough childhood topics such as bullying or having a new baby in the family, Carlson manages to find a reassuring approach, said Lisa Von Drasek, curator of the Children’s Literature Research Collections at the University of Minnesota Libraries.
“Nancy gives voice to the everyday lives of children,” Van Drasek said. “She respects their emotions and their fears. It’s funny, you laugh, but there’s something at the core that she nails, that you recognize as real. It’s her gift.”
A team approach
Carlson and McCool met when they were in their 20s. Carlson, who had just graduated from the Minneapolis College of Art and Design, was working as a lifeguard at the Blaisdell YMCA, where McCool swam.
After they married, her books quickly found a broad audience. By the time their third and final child was born, Carlson had more than a dozen books in print and had become a popular speaker in schools and libraries.
She was so successful that McCool sold the design company he had formed to oversee the sales and marketing of her books, schedule her appearances and negotiate her contracts.
“Both of my parents worked at home, and that was unusual at the time, but it was great for us,” said their son Mike McCool, now 25. “She was the artist and he was the organized, precise, punctual one.”
By all accounts, they were a happy, busy family, enjoying their Bloomington home with its back-yard pool, their cabin, their summertime road trips in the family van.
“I had the best childhood ever,” said their daughter Kelly McCool Rebhorn, 31. “My parents were supportive, loving, hardworking — great role models. My dad started a business from nothing, and my mom, well, she created a whole world.”
Carlson can’t quite pinpoint when McCool’s descent began, but the husband she’d regarded as mild-mannered gradually turned moody, silent, sometimes belligerent. She wondered if the changes were the result of aging or a part of a couple’s recalibration as their children left home.
For the first time, they quarreled over her career.
“I was so angry with him. I thought he was spending time on the wrong things,” she said. “He had this idea about licensing my characters, and he wouldn’t give it up even when it became clear it wasn’t going anywhere.”
Rebhorn saw it, as well. “He was causing problems and he wouldn’t explain himself. We didn’t understand that he couldn’t.”
McCool got behind on bills, which ran up late charges and put them deeper in debt. He stopped paying taxes, mismanaged his children’s college loan payments, then began taking out loans in his wife’s and children’s names.
“When it finally all came out, it was pretty catastrophic,” Mike McCool said. “It was like when you have an injury and at first you’re afraid to look because you don’t want to know how bad it is.”
The royalty checks no longer covered the losses, which started to pile up. Eventually, they lost their health insurance. Barry McCool hustled to find work, but couldn’t hold a job. The couple moved six times in two years, landing in an apartment complex where McCool took on maintenance and cleaning chores to reduce their rent. Carlson wound up doing much of it, shoveling snow for hours.
One day the building manager stopped her. “She said, ‘I just found out who you are. My kids know all your books,’ ” Carlson recalled. “Then she looks at me and goes, ‘What in the heck are you doing here?’ ”
Missing ‘the detail guy’
It wasn’t until late 2012 that McCool’s condition was finally diagnosed. For Carlson, it was devastating — and a relief. “I could stop being mad at him,” she said. “We could see that this wasn’t his fault.”
She said she considers the months right after the diagnosis as their last good time together. While her husband went to day care, she had time to recharge and refocus on her work. But within a few months, he declined again.
“I wasn’t strong enough to control him,” she said. “He was impulsive; he could make a run for it.”
Now Carlson visits McCool at the nursing home almost every day, even though he recognizes her less often. His speech is limited and he shows little expression, except when Rebhorn arrives with her two young daughters. “His face lights up when he sees my girls,” Rebhorn said. “I think he knows.”
Through it all, Carlson has never put her pen down. She kept drawing, and even built an online audience for the sketch she posts on her website (www.nancycarlson.com) every morning. She writes and gives readings and holds workshops. She’s also preparing for a show and sale of her work in December. (She plans to donate 20 percent of the profits to the Association for Frontotemporal Degeneration for research into the disorder.)
In the bedroom-turned-studio of her apartment in Bloomington, her drawing table sits next to a window that overlooks a parking lot.
“Barry would have caught that,” she said. “He was the detail guy. Before we would have rented this place, he would have walked around the building and said, ‘No, let’s find a unit with a better view for you.’ ”
Carlson acknowledges that it’ll take her years to right her finances and to get used to being on her own. But she’s confident that she can do it.
“As long as I can keep drawing, I know I’m OK.”
Kevyn Burger is a freelance writer. | <urn:uuid:3b8c2fd1-6aa1-48a9-8e77-985c58ec77a9> | CC-MAIN-2022-33 | https://m.startribune.com/amid-loss-minn-author-nancy-carlson-still-makes-children-s-books/281247771/ | s3://commoncrawl/crawl-data/CC-MAIN-2022-33/segments/1659882573193.35/warc/CC-MAIN-20220818094131-20220818124131-00474.warc.gz | en | 0.986938 | 1,753 | 1.65625 | 2 |
Subsets and Splits