update MedS-Bench

update MedS-Bench. Replace some datasets with the official train-test split with the official test set, and balance the number of labels of True of False in the Clinical_outcome_prediction task.

.gitattributes

@@ -61,3 +61,5 @@ MedS-Bench/Clinical_outcome_prediction/task118_mimic4ed_72h_ed_revisit_dispositi
 MedS-Bench/Clinical_outcome_prediction/task119_mimic4ed_benchmark_critical_triage.json filter=lfs diff=lfs merge=lfs -text
 MedS-Bench/Diagnosis/task130_DDXPlus_text_classification_test.json filter=lfs diff=lfs merge=lfs -text
 MedS-Bench/Information_extraction/task74_pmc_patient_case_report_basic_information_extraction.json filter=lfs diff=lfs merge=lfs -text
+Diagnosis/task130_DDXPlus_text_classification_test.json filter=lfs diff=lfs merge=lfs -text
+Information_extraction/task74_pmc_patient_case_report_basic_information_extraction.json filter=lfs diff=lfs merge=lfs -text

Diagnosis/task130_DDXPlus_text_classification_test.json

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b70f2c5ca1820bb2cc82e5d0971a5b83174c0cb29a57945bb39e880bf83a92cc
+size 168937567

Information_extraction/task1_participant_extraction.json

@@ -0,0 +1,361 @@
+{
+    "Contributors": [
+        "Pegah Alipoormolabashi"
+    ],
+    "Source": [
+        "pico"
+    ],
+    "URL": [
+        "https://github.com/Markus-Zlabinger/pico-annotation"
+    ],
+    "Categories": [
+        "Information Extraction"
+    ],
+    "Reasoning": [],
+    "Definition": [
+        "In medical studies, treatments are tested within a group of study participants. You will be given a sentence of a study report in which your task is to list the phrases that give information about the participants of the study. You should list the phrases in the same order that they appear in the text, separated by commas. If no information about the participants is mentioned, just output \"not found\". Relevant information about participants include: gender, medical conditions, location, number of people participating. Do not contain participant mentions without relevant information."
+    ],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Academical Papers",
+        "Clinical Trials and Controlled Trials"
+    ],
+    "Positive Examples": [
+        {
+            "input": "A PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD Lipid. ",
+            "output": "Type 2 Diabetes",
+            "explanation": "The only piece of text relevant to participants is \"Type 2 Diabetes\" which is a medical condition."
+        },
+        {
+            "input": "A total of 270 patients with MCI were enrolled in a 24-week, multicenter, randomized, double-blind, placebo-controlled study.",
+            "output": "270 patients with MCI",
+            "explanation": "In this example, both the number of participants and their medical condition is mentioned."
+        }
+    ],
+    "Negative Examples": [
+        {
+            "input": "A total of 270 patients with MCI were enrolled in a 24-week, multicenter, randomized, double-blind, placebo-controlled study.",
+            "output": "270 patients with MCI, 24-week",
+            "explanation": "The duration of the study is not relevant to the participants and shouldn't be included."
+        },
+        {
+            "input": " To investigate the role of nicotinamide adenine dinucleotide phosphate 4 (NADPH4,NOX4) and transforming growth factor-beta (TGF-\u03b2) involve in pathogenesis of airway remodeling in chronic obstructive pulmonary disease (COPD).",
+            "output": "COPD",
+            "explanation": "The complete name of the disease (chronic obstructive pulmonary disease) should be included."
+        }
+    ],
+    "Instances": [
+        {
+            "id": "task179-bf49dbf887b640009915afb129c0f695",
+            "input": "Under Fluoxetine , mPFC activation was up-regulated and normalized in ASD boys relative to controls , but down-regulated in ADHD boys relative to placebo , which was concomitant with worse task performance in ADHD .",
+            "output": [
+                "ASD boys, ADHD boys"
+            ]
+        },
+        {
+            "id": "task179-35a05d694d9946faa08e9c5b191e2f94",
+            "input": "We conclude that granisetron is a better anti-emetic than perphenazine for the long-term prevention of post-operative vomiting in children undergoing general anaesthesia for tonsillectomy .",
+            "output": [
+                "children undergoing general anaesthesia for tonsillectomy"
+            ]
+        },
+        {
+            "id": "task179-3718eea27d6741cd8f6a3bb94d83fb04",
+            "input": "One case of unsubstantiated acute rheumatic fever occurred after 7 days of amoxicillin .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-fcf448b8dbba44f8aad1d13e6386b29b",
+            "input": "Costs/QALY gained discounted at 3 % were $ 205,186 using the QWB and $ 32,643 using the CHRD .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-696254fa5c074cd584e90ae9ff75cdfd",
+            "input": "Calcium solubility and absorption across Caco-2 cells were studied after the in vitro digestion of the diets .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-9baddb311e6b4a02a72715fa025ec144",
+            "input": "Influence of diets rich in Maillard reaction products on calcium bioavailability .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-0d40536a321943789c31e41985c3e9bf",
+            "input": "Prior adjuvant chemotherapy was permitted .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-d064ad23500949eda605b7754c44b2e6",
+            "input": "Depressive patients are able to follow prescribed lifestyle recommendations in the short-term .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-6834f4e07f0d4af294ca29f9c12b1f44",
+            "input": "The influence of injections of Amidotrizoate and Iopromide into the left coronary artery on global myocardial perfusion and function ( pressures in the left ventricle , heart rate ) as well as excitation formation and transmission was studied in 16 patients with ischaemic heart disease .",
+            "output": [
+                "16 patients with ischaemic heart disease"
+            ]
+        },
+        {
+            "id": "task179-7eb920c6b3864eb88ef8b9e74696ab46",
+            "input": "These 22 patients constituted the control group of a controlled trial and received standard outpatient clinic treatment during follow-up .",
+            "output": [
+                "22 patients"
+            ]
+        },
+        {
+            "id": "task179-48f17a1f7a204cb09f35692e2a29a7fd",
+            "input": "Patients could not have had prior chemotherapy for metastatic disease .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-589d31b21098423ab45ba7cf0c87773a",
+            "input": "Comparisons with the cyclophosphamide-doxorubicin-5-fluorouracil arm will not be addressed .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-25e87d16f93b4d3b85e6f89f82b3df53",
+            "input": "Children with parent-reported ASD had higher levels of health care office visits and prescription drug use compared with children without ASD ( P < .05 ) .",
+            "output": [
+                "children without ASD"
+            ]
+        },
+        {
+            "id": "task179-939c393e042a4a3f8e01f73970c8a3a6",
+            "input": "Short-term phasic activity was only found in 13 out of 40 of the normal infants ( 32.5 % ) .",
+            "output": [
+                "40 of the normal infants"
+            ]
+        },
+        {
+            "id": "task179-52213a2b2e034ab4ab901f6a046c9da7",
+            "input": "Group 1 received a weekly session of posterior tibial nerve stimulation for 12 weeks and group 2 was the placebo group .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-48aced4b625940978be2b146c53acecf",
+            "input": "Only deoxypyridinoline values were significantly lower after consumption of the BD ( 13.0 +/- 1.1 compared to 18.3 +/- 2.1 nM/Mm Cr in the WD ) , possibly indicative of less efficient bone turnover during this period .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-f6baa8c89ec948209789c4d1586f42d0",
+            "input": "The results suggest that the use of PMRT could enhance quality of life and decrease state anxiety in patients after stoma surgery .",
+            "output": [
+                "patients after stoma surgery"
+            ]
+        },
+        {
+            "id": "task179-883e978e6b7145118dcbe55c95721b0b",
+            "input": "Interventions were conducted 30 min daily for 5-6 weeks .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-0f94638fd62441a489349ba3fca4204f",
+            "input": "There were also no differences in manual muscle testing sum scores , activity scale scores and patients ' own assessments after 48 weeks of treatment .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-37556951072c41b6b6c456cc03118985",
+            "input": "However , transfusion rate , presence of hepatomegaly , splenomegaly , and jaundice was similar .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-cd1e891d328b4375bc30df492cbe1206",
+            "input": "Three hundred sixty-five patients were enrolled .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-44ec843ccf9e40d19fe82b4e161c5e3a",
+            "input": "If so , this would be a great support for doctors who might systematically recommend these simple and costless measures , especially in primary care .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-9c1461f976dd4a4a9a8e781463537c9b",
+            "input": "Relative to children in the wait-list group , program participants showed greater improvements in social skills over the course of the intervention , as indicated by parent-report measures .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-9a3ff97c4c484c5f9386e98f6bbbe48b",
+            "input": "Hence , we hypothesize that specific airway resistance changes ( \u0394sRAW ) should better characterize the acute response to bronchodilators .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-c6951bf1a5a24b9eb074b1f2fa78c0bf",
+            "input": "We investigated whether 13 participants with ASD ( age 7 ; 03-22 ; 03 ) and 13 age-matched typically developing ( TD ) controls could comprehend lexicalized conceptual metaphors ( e.g. , Susan is a warm person ) and novel ones ( e.g. , Susan is a toasty person ) .",
+            "output": [
+                "13 participants with ASD, 13 age-matched typically developing ( TD"
+            ]
+        },
+        {
+            "id": "task179-b089accc025245bd83159f07931df61d",
+            "input": "Randomized controlled study of chemoimmunotherapy with bestatin of acute nonlymphocytic leukemia in adults .",
+            "output": [
+                "acute nonlymphocytic leukemia in adults"
+            ]
+        },
+        {
+            "id": "task179-8d4b758964634113b4936f00bb66711e",
+            "input": "Forty-nine children with AS were recruited to participate and randomly assigned to intervention ( n = 26 ) or wait-list control ( n = 23 ) conditions .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-6ab5c6f01bcc44169deb95557df33d33",
+            "input": "Observed medication and weekend diary cards were used to monitor adherence .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-83b138183afb411da40a9ff452ad56a9",
+            "input": "Use of health care facilities was assessed from diaries/questionnaires and Medicare reimbursement rates used to estimate costs .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-b29361fada3843eeaff238b640582ddb",
+            "input": "In 78 children known to be infected with Ascaris at baseline , the rate of weight gain was 21 per cent greater in children treated with levamisole than in those receiving placebo ( p = .03 ) .",
+            "output": [
+                "78 children known to be infected with Ascaris"
+            ]
+        },
+        {
+            "id": "task179-df2105dc2ea34d5781f8a90746052ae6",
+            "input": "Overall , 13 patients ( 46.4 % ) had detrusor overactivity and 14 ( 50 % ) had decreased bladder capacity .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-a1a624c2133249fa8aedfc9741283a67",
+            "input": "In patients with neutrophil counts of > 0.1 x 10 ( 9 ) /L lasting for more than 4 weeks , the frequency of infection in the fluconazole group ( 5 of 9 patients ) was significantly higher than in the itraconazole group ( 0 of 7 patients ; P = .03 ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-47c995de3c8a457e84fc6e8f6ce10f91",
+            "input": "No significant differences , within and between groups , were observed in the exercise-induced increase in the ratios para- and ortho-hydroxyantipyrine to antipyrine .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-3e0154d08378446cbd15f25bd49607fa",
+            "input": "Age-matched boys with ADHD ( 15 ) , ASD ( 18 ) , and controls ( 21 ) were compared with functional magnetic resonance imaging ( fMRI ) during a reversal task .",
+            "output": [
+                "15 ) , ASD, 18 ) , and controls, 21"
+            ]
+        },
+        {
+            "id": "task179-c206f3baf1c44b43a2201617b0b1bb0b",
+            "input": "This 7-week program included a computer game , small group sessions , parent training sessions and teacher handouts .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-08d53ca8191c43b2b17fe6ca04cd8349",
+            "input": "The patients were randomised into a control group ( n = 10 ) and an experimental group ( n = 8 ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-ba6209c1215d44dab55a184296623542",
+            "input": "To consider the impact on primary care patient outcomes of using both a screener to determine elevated anxiety levels among patients with previously undetected anxiety and a physician intervention to inform physicians of their patients ' conditions .",
+            "output": [
+                "patients with previously undetected anxiety"
+            ]
+        },
+        {
+            "id": "task179-fd09cf9efe3e4a0d8697a181d09e5a1a",
+            "input": "A persistent phasic activity pattern was found in 19 of the 21 patients , high frequency phasic activity in 11 of the 21 patients .",
+            "output": [
+                "21 patients"
+            ]
+        },
+        {
+            "id": "task179-895cc0bdc24640f38dfd1893b1f21fab",
+            "input": "In a prospective , randomized , double-blind study , 90 paediatric patients , ASA I , aged 4-10 years , received granisetron 40 mg kg-1 or perphenazine 70 mg kg-1 ( n = 45 each ) intravenously immediately after an inhalation induction of anaesthesia .",
+            "output": [
+                "90 paediatric patients, ASA I , aged 4-10 years"
+            ]
+        },
+        {
+            "id": "task179-dbb5eaf8c6344a96993cc7cd7af33ef8",
+            "input": "After three weekly doses of epoetin alfa 40,000 U , a dose of 120,000 U can be administered safely once every 3 weeks without increasing transfusion needs or sacrificing QOL .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-788778a502214fa08a4c6c7b50f0b220",
+            "input": "However , to our knowledge , there have been no studies using all these measures together as an adjuvant antidepressant strategy .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-3e5d819e6c274c539bb503af68283933",
+            "input": "Accordingly , the current study examined within-person covariation between time-varying abstinence and depressive symptom in a multilevel model ( MLM ) , which allowed for transitions between smoking statuses within a participant .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task179-7715c218357044049a1d3b38cedb5566",
+            "input": "Internal stenting is an integral part of endopyelotomy .",
+            "output": [
+                "not found"
+            ]
+        }
+    ],
+    "Instance License": [
+        "Unknown"
+    ]
+}

Information_extraction/task29_drug_dose_extraction.json

@@ -0,0 +1,223 @@
+{
+    "Contributors": [
+        "Ishani Mondal"
+    ],
+    "Source": [
+        "ade_corpus_v2"
+    ],
+    "URL": [
+        "https://github.com/trunghlt/AdverseDrugReaction/tree/master/ADE-Corpus-V2"
+    ],
+    "Categories": [
+        "Information Extraction"
+    ],
+    "Reasoning": [],
+    "Definition": [
+        "In this task, you will be given sentences and a drug name in which your task is to indicate the doses of intake of that particular drug. A dose refers to a specified amount of medication taken at one time. Although there might be several correct answers, you need to write one of them."
+    ],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Clinical Knowledge",
+        "Drug",
+        "Academical Papers",
+        "Healthcare"
+    ],
+    "Positive Examples": [
+        {
+            "input": "An episode of subacute encephalopathy after the infusion of methotrexate (1500 mg/m2) (MTX) is reported in a young adult with metastastic gastric cancer.\t methotrexate",
+            "output": "1500 mg/m2",
+            "explanation": "Here, the drug methotrexate mentioned after '\t ' has been mentioned to be taken as 1500 mg/m2 within brackets and hence should be tagged as dosage."
+        },
+        {
+            "input": "A case of normotensive scleroderma renal crisis after high-dose methylprednisolone treatment.\t methylprednisolone",
+            "output": "high",
+            "explanation": "Amount of methylprednisolone is taken in high amount and hence should be tagged with that."
+        }
+    ],
+    "Negative Examples": [
+        {
+            "input": "Ibuprofen overdose is usually characterized by GI upset, dizziness, and mild sedation\t ibuprofen",
+            "output": "mild",
+            "explanation": "Here the drug ibuprofen has been mentioned to be taken in excess but mild is the qualifier of the sedation caused by overdose of the drug, hence mild should not be tagged as drug dosage."
+        },
+        {
+            "input": "She took three doses of methotrexate and two doses of ibuprofen.\t methotrexate",
+            "output": "two",
+            "explanation": "Amount of methotrexate is taken in three doses and hence should be tagged with that, instead of the the dosage mentioned for ibuprofen."
+        }
+    ],
+    "Instances": [
+        {
+            "id": "task1451-4a32996c896e4ba4af9bb6cfb4628ce7",
+            "input": "METHODS: Growth retardation was observed in six severely asthmatic children after introduction of high-dose fluticasone propionate treatment (dry powder).\t fluticasone propionate",
+            "output": [
+                "high"
+            ]
+        },
+        {
+            "id": "task1451-379dc9b35d49462c9722445d9c2f2649",
+            "input": "Two case reports of bilateral granulomatous anterior uveitis are described in patients with open angle glaucoma treated with metripranolol 0.6% eye drops.\t metripranolol",
+            "output": [
+                "0.6"
+            ]
+        },
+        {
+            "id": "task1451-8264c178667641dbac8a59d7d5cf3af4",
+            "input": "This case suggests that acyclovir when given intravenously in doses of 10 mg/kg may result in increased serum lithium concentrations.\t acyclovir",
+            "output": [
+                "10 mg/kg"
+            ]
+        },
+        {
+            "id": "task1451-3fe69c5ac6974445821bc19e3d99b957",
+            "input": "This case suggests that acyclovir when given intravenously in doses of 10 mg/kg may result in increased serum lithium concentrations.\t lithium",
+            "output": [
+                "10 mg/kg"
+            ]
+        },
+        {
+            "id": "task1451-58de8f0c9a7c41a98d914e73b65a7092",
+            "input": "We describe 2 patients with cutaneous lupus erythematosus who developed severe dapsone reaction after low dose therapy, with a fatal outcome in one.\t dapsone",
+            "output": [
+                "low"
+            ]
+        },
+        {
+            "id": "task1451-d84ef3cd7442478f9fb4bd123f83fc0e",
+            "input": "A 17-year-old female patient who had been taking oral minocycline (50 mg twice daily) for 3 weeks for acne developed an eruption that progressed to an exfoliative dermatitis.\t minocycline",
+            "output": [
+                "50 mg twice daily"
+            ]
+        },
+        {
+            "id": "task1451-91e06a4b953148f1927f6aab52b281f1",
+            "input": "Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis.\t magnesium",
+            "output": [
+                "Overdose"
+            ]
+        },
+        {
+            "id": "task1451-4452acb10e8f45d599299bcbe9fb52f9",
+            "input": "Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis.\t magnesium sulfate",
+            "output": [
+                "Overdose"
+            ]
+        },
+        {
+            "id": "task1451-24ddea23892a4383825f3a0de39379e8",
+            "input": "We thus concluded that an excessive dose of AZ had probably destroyed the gastric mucosal barrier or thrombocytopenia due to bone marrow disorder and thus eventually led to the development of hemorrhagic gastritis.\t AZ",
+            "output": [
+                "excessive"
+            ]
+        },
+        {
+            "id": "task1451-dbc58ce2ac684f3988b14a8ca41ecd2b",
+            "input": "On the next day, after a total dose of only 600 mg of danazol, gingival bleeding and purpura occurred.\t danazol",
+            "output": [
+                "600 mg"
+            ]
+        },
+        {
+            "id": "task1451-264c8c79515645daa399c5fbe6116ec9",
+            "input": "We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d-penicillamine 125-500 mg daily.\t d-penicillamine",
+            "output": [
+                "125-500 mg daily"
+            ]
+        },
+        {
+            "id": "task1451-6bac619b162247e88129e1ae1a6b663d",
+            "input": "Ballistic movements due to ischemic infarcts after intravenous heroin overdose: report of two cases.\t heroin",
+            "output": [
+                "overdose"
+            ]
+        },
+        {
+            "id": "task1451-4129f9617c6141f2b4d32e63dc3bccec",
+            "input": "Two heroin addicts, aged 34 and 19 years, developed ballistic movements after intravenous heroin overdose.\t heroin",
+            "output": [
+                "overdose"
+            ]
+        },
+        {
+            "id": "task1451-7d660f0a50b7419391d8fb207e5277bc",
+            "input": "We report a 76-year-old man who developed an acute blistering eruption following high-dose penicillin treatment for pneumococcal septicaemia.\t penicillin",
+            "output": [
+                "high"
+            ]
+        },
+        {
+            "id": "task1451-d6c36849063c4dc8904a5bfb5f1882dd",
+            "input": "In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.\t desmethylsertraline",
+            "output": [
+                "25 mg"
+            ]
+        },
+        {
+            "id": "task1451-07560d07eae343728fa11a31574137b2",
+            "input": "In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.\t lamotrigine",
+            "output": [
+                "25 mg"
+            ]
+        },
+        {
+            "id": "task1451-016380dbada7461193068a44a8786e8e",
+            "input": "We report a case of pancytopenia in a 23-year-old man with Crohn's disease who was treated with 5-aminosalicylic acid (Pentasa; Nisshin, Tokyo, Japan) 3.0 g/day.\t 5-aminosalicylic acid",
+            "output": [
+                "3.0 g/day"
+            ]
+        },
+        {
+            "id": "task1451-c4b2a8dc1f29437291ab2a1c13fd7826",
+            "input": "We report a case of pancytopenia in a 23-year-old man with Crohn's disease who was treated with 5-aminosalicylic acid (Pentasa; Nisshin, Tokyo, Japan) 3.0 g/day.\t Pentasa",
+            "output": [
+                "3.0 g/day"
+            ]
+        },
+        {
+            "id": "task1451-ffc8a60083354d3b8dc3488744ded11c",
+            "input": "1. Changes in the plasma cortisol level were reported in a male patient with panic disorder during the period of low-dose alprazolam treatment (mean 0.62 +/- 0.15 mg/day) compared with during the period of high-dose period (mean 1.08 +/- 0.28 mg/day).\t alprazolam",
+            "output": [
+                "low"
+            ]
+        },
+        {
+            "id": "task1451-e61b0a4e61c44deda1a3cbcbf0eaa8bd",
+            "input": "We report on three patients with acute schizophrenia, who developed severe akathisia during treatment with olanzapine (20-25 mg/d).\t olanzapine",
+            "output": [
+                "20-25 mg/d"
+            ]
+        },
+        {
+            "id": "task1451-5c9e9c67600f4dbe8df63b116cb32d1f",
+            "input": "A 65-year-old woman with angina pectoris presented with syncope after sublingual ingestion of isosorbide dinitrate (5 mg).\t isosorbide dinitrate",
+            "output": [
+                "5 mg"
+            ]
+        },
+        {
+            "id": "task1451-aec3411cd2c048e5a09d907bf90635e5",
+            "input": "In a postural challenge test after administration of isosorbide dinitrate (5 mg), blood pressure decreased from 120/67 to 65/35 mmHg, followed by syncope with a sudden decrease in pulse rate from 85 to 60 beats/min.\t isosorbide dinitrate",
+            "output": [
+                "5 mg"
+            ]
+        },
+        {
+            "id": "task1451-92a7576e81a14e4e9f3bfd78ae7bb175",
+            "input": "High-dose phosphate treatment leads to hypokalemia in hypophosphatemic osteomalacia.\t phosphate",
+            "output": [
+                "High"
+            ]
+        }
+    ],
+    "Instance License": [
+        "Unknown"
+    ]
+}

Information_extraction/task2_intervention_extraction.json

@@ -0,0 +1,371 @@
+{
+    "Contributors": [
+        "Pegah Alipoormolabashi"
+    ],
+    "Source": [
+        "pico"
+    ],
+    "URL": [
+        "https://github.com/Markus-Zlabinger/pico-annotation"
+    ],
+    "Categories": [
+        "Information Extraction"
+    ],
+    "Reasoning": [],
+    "Definition": [
+        "In medical studies, the efficacy of medical treatments (called interventions) is evaluated within a group of study participants. You will be given a sentence of a study report in which your task is to list the phrases that describe the intervention(s) of the study. You should list the phrase in the same order that they appear in the text, separated by commas. If no information about the interventions is mentioned, just answer with \"not found\". Interventions are: a specific drug, surgery, talking therapy, a lifestyle modification, control or placebo treatment. Do not include details, dosages, frequency and duration, intervention mentions that are not in an informative span of text."
+    ],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Academical Papers",
+        "Clinical Trials and Controlled Trials"
+    ],
+    "Positive Examples": [
+        {
+            "input": "The patients received either azithromycin (600 mg/d for 3 days during week 1, then 600 mg/wk during weeks 2-12; n = 3879) or placebo (n = 3868)",
+            "output": "azithromycin, placebo",
+            "explanation": "The word azithromycin refers to a drug, and placebo refers to a control test. Note that no extra information is given in the output."
+        },
+        {
+            "input": "We report findings of a pilot RCT for a parent training intervention with a focus on the development of joint attention skills and joint action routines. ",
+            "output": "parent training intervention",
+            "explanation": "The words parent, training, and intervention refer to some kind of talking therapy."
+        },
+        {
+            "input": "Seventy-two people residing in National Health Service (U.K.) care facilities who had clinically significant agitation in the context of severe dementia were randomly assigned to aromatherapy with Melissa essential oil (N = 36) or placebo (sunflower oil) (N = 36). ",
+            "output": "aromatherapy with melissa essential oil, placebo, sunflower oil",
+            "explanation": "Both the therapy and the control treatment are mentioned as spans of text here."
+        }
+    ],
+    "Negative Examples": [
+        {
+            "input": "Treatment consisted of nitrendipine (10-40 mg/d), with the possible addition of enalapril maleate (5-20 mg/d), hydrochlorothiazide (12.5-25 mg/d), or both add-on drugs.",
+            "output": "nitrendipine (10-40 mg/d, ), enalapril, maleate (5-20, mg/d), hydrochlorothiazide (12.5-25, mg/d), both add-on drugs",
+            "explanation": "The drugs are correctly mentioned as intervention, but their dosage shouldn't be given as answer."
+        },
+        {
+            "input": "Zinc lozenges, 10 mg, orally dissolved, 5 times a day (in grades 1-6) or 6 times a day (in grades 7-12). ",
+            "output": "Zinc lozenges, orally dissolved",
+            "explanation": "Information about the method the intervention is given to patients, in this case \"orally dissolved\" should not be given as answer."
+        },
+        {
+            "input": "Antihypertensive therapy was started immediately after randomization in the active treatment group, but only after termination of the double-blind trial in the control patients.",
+            "output": "Antihypertensive therapy, double-blind trial",
+            "explanation": "The words double-blind and trial are not related to intervention."
+        }
+    ],
+    "Instances": [
+        {
+            "id": "task180-d05f132280184d30b2a7c66a12955f4f",
+            "input": "Under Fluoxetine , mPFC activation was up-regulated and normalized in ASD boys relative to controls , but down-regulated in ADHD boys relative to placebo , which was concomitant with worse task performance in ADHD .",
+            "output": [
+                "Fluoxetine, placebo"
+            ]
+        },
+        {
+            "id": "task180-705583d0b7574261a1d0eb3b9ea21f25",
+            "input": "We conclude that granisetron is a better anti-emetic than perphenazine for the long-term prevention of post-operative vomiting in children undergoing general anaesthesia for tonsillectomy .",
+            "output": [
+                "granisetron, perphenazine"
+            ]
+        },
+        {
+            "id": "task180-e05d4b47a48c455fa73c230a1dc61ede",
+            "input": "One case of unsubstantiated acute rheumatic fever occurred after 7 days of amoxicillin .",
+            "output": [
+                "amoxicillin"
+            ]
+        },
+        {
+            "id": "task180-4b5d472d7ad84ff5bc8c9336e2906d63",
+            "input": "Costs/QALY gained discounted at 3 % were $ 205,186 using the QWB and $ 32,643 using the CHRD .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-1e26affc2bf84ba28b3e04ca11d21c4d",
+            "input": "Calcium solubility and absorption across Caco-2 cells were studied after the in vitro digestion of the diets .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-2bf7946e98cd4de38087368b5b359e79",
+            "input": "Influence of diets rich in Maillard reaction products on calcium bioavailability .",
+            "output": [
+                "Maillard reaction"
+            ]
+        },
+        {
+            "id": "task180-ed2cbf7a61b9470b9ca0ba3cb93c9bfe",
+            "input": "Prior adjuvant chemotherapy was permitted .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-5e208cd3d15d4e74bc2f6a1a15d4e74c",
+            "input": "Depressive patients are able to follow prescribed lifestyle recommendations in the short-term .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-b095127d871449a488f0097adab5cb81",
+            "input": "The influence of injections of Amidotrizoate and Iopromide into the left coronary artery on global myocardial perfusion and function ( pressures in the left ventricle , heart rate ) as well as excitation formation and transmission was studied in 16 patients with ischaemic heart disease .",
+            "output": [
+                "Amidotrizoate, Iopromide"
+            ]
+        },
+        {
+            "id": "task180-6a8c5ed874fb4012af3091a5c3d3e043",
+            "input": "These 22 patients constituted the control group of a controlled trial and received standard outpatient clinic treatment during follow-up .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-9e5b32d1dd48404496afa9349b44db5c",
+            "input": "Patients could not have had prior chemotherapy for metastatic disease .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-6a3f1f6bded24064806c331e1da2dc6f",
+            "input": "Comparisons with the cyclophosphamide-doxorubicin-5-fluorouracil arm will not be addressed .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-93498bba94674cbfa26fd8c2fb59fa8b",
+            "input": "Children with parent-reported ASD had higher levels of health care office visits and prescription drug use compared with children without ASD ( P < .05 ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-fcc6bb6f4136434b96c9162a22134038",
+            "input": "Short-term phasic activity was only found in 13 out of 40 of the normal infants ( 32.5 % ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-5889efe2ac4f41e488bd6f90202b8ed7",
+            "input": "Group 1 received a weekly session of posterior tibial nerve stimulation for 12 weeks and group 2 was the placebo group .",
+            "output": [
+                "posterior tibial nerve stimulation, placebo"
+            ]
+        },
+        {
+            "id": "task180-dc4ee1c5234f443a9d0a8e698b1c9c52",
+            "input": "Only deoxypyridinoline values were significantly lower after consumption of the BD ( 13.0 +/- 1.1 compared to 18.3 +/- 2.1 nM/Mm Cr in the WD ) , possibly indicative of less efficient bone turnover during this period .",
+            "output": [
+                "BD"
+            ]
+        },
+        {
+            "id": "task180-add4b106e93746b68f4e1f1e8d39e293",
+            "input": "The results suggest that the use of PMRT could enhance quality of life and decrease state anxiety in patients after stoma surgery .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-51c88bc4a6f645b9a7070e2ff507bf44",
+            "input": "Interventions were conducted 30 min daily for 5-6 weeks .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-734141f8c527467cbaa543c60cf7632d",
+            "input": "There were also no differences in manual muscle testing sum scores , activity scale scores and patients ' own assessments after 48 weeks of treatment .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-e61f739b28d04c8fa6d3eff3a350af3a",
+            "input": "However , transfusion rate , presence of hepatomegaly , splenomegaly , and jaundice was similar .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-f8139b79b39d48afb5790bf20cfc0eca",
+            "input": "Three hundred sixty-five patients were enrolled .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-064aac9cb0b24fa2aae6a0b57b428348",
+            "input": "If so , this would be a great support for doctors who might systematically recommend these simple and costless measures , especially in primary care .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-a2a322cc0dbf4e7886a234514fe49b5c",
+            "input": "Relative to children in the wait-list group , program participants showed greater improvements in social skills over the course of the intervention , as indicated by parent-report measures .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-5c7e821690ca43798ada163a1c435260",
+            "input": "Hence , we hypothesize that specific airway resistance changes ( \u0394sRAW ) should better characterize the acute response to bronchodilators .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-4f9a49878df14dccaace0ce051371d4e",
+            "input": "We investigated whether 13 participants with ASD ( age 7 ; 03-22 ; 03 ) and 13 age-matched typically developing ( TD ) controls could comprehend lexicalized conceptual metaphors ( e.g. , Susan is a warm person ) and novel ones ( e.g. , Susan is a toasty person ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-bbfca44a968647df974d397c09064de9",
+            "input": "Randomized controlled study of chemoimmunotherapy with bestatin of acute nonlymphocytic leukemia in adults .",
+            "output": [
+                "chemoimmunotherapy, bestatin"
+            ]
+        },
+        {
+            "id": "task180-4307ceaeaffc44dd98a1b1dde9b55c64",
+            "input": "Forty-nine children with AS were recruited to participate and randomly assigned to intervention ( n = 26 ) or wait-list control ( n = 23 ) conditions .",
+            "output": [
+                "wait-list control"
+            ]
+        },
+        {
+            "id": "task180-9adf342a2f844b1794587e21459bf3c2",
+            "input": "Observed medication and weekend diary cards were used to monitor adherence .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-df2cc246edd74f9d96d0da5eafcde9a9",
+            "input": "Use of health care facilities was assessed from diaries/questionnaires and Medicare reimbursement rates used to estimate costs .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-639b1456c54a41efbe7f35ae81615ee3",
+            "input": "In 78 children known to be infected with Ascaris at baseline , the rate of weight gain was 21 per cent greater in children treated with levamisole than in those receiving placebo ( p = .03 ) .",
+            "output": [
+                "levamisole, placebo"
+            ]
+        },
+        {
+            "id": "task180-4062f1dc9324413e80924a911200b818",
+            "input": "Overall , 13 patients ( 46.4 % ) had detrusor overactivity and 14 ( 50 % ) had decreased bladder capacity .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-b287b8fac5a845f882cede4db5e321b1",
+            "input": "In patients with neutrophil counts of > 0.1 x 10 ( 9 ) /L lasting for more than 4 weeks , the frequency of infection in the fluconazole group ( 5 of 9 patients ) was significantly higher than in the itraconazole group ( 0 of 7 patients ; P = .03 ) .",
+            "output": [
+                "fluconazole, itraconazole"
+            ]
+        },
+        {
+            "id": "task180-679cf1cc391f4271be693b9bceb5dc45",
+            "input": "No significant differences , within and between groups , were observed in the exercise-induced increase in the ratios para- and ortho-hydroxyantipyrine to antipyrine .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-516f779dd64c4044879904eee1d241bc",
+            "input": "Age-matched boys with ADHD ( 15 ) , ASD ( 18 ) , and controls ( 21 ) were compared with functional magnetic resonance imaging ( fMRI ) during a reversal task .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-aa9bc54083594cdb9740e335fa5a48cb",
+            "input": "This 7-week program included a computer game , small group sessions , parent training sessions and teacher handouts .",
+            "output": [
+                "computer game, small group sessions, parent training, teacher handouts"
+            ]
+        },
+        {
+            "id": "task180-e99ffd4d7c9e416a872445b27329251c",
+            "input": "The patients were randomised into a control group ( n = 10 ) and an experimental group ( n = 8 ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-a841268b7d464f03a461a609cb1a9033",
+            "input": "To consider the impact on primary care patient outcomes of using both a screener to determine elevated anxiety levels among patients with previously undetected anxiety and a physician intervention to inform physicians of their patients ' conditions .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-3fcdfafaddbe4eba9de0668b526ac345",
+            "input": "A persistent phasic activity pattern was found in 19 of the 21 patients , high frequency phasic activity in 11 of the 21 patients .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-e0f406fe59c04444b11699f4fdc2a11c",
+            "input": "In a prospective , randomized , double-blind study , 90 paediatric patients , ASA I , aged 4-10 years , received granisetron 40 mg kg-1 or perphenazine 70 mg kg-1 ( n = 45 each ) intravenously immediately after an inhalation induction of anaesthesia .",
+            "output": [
+                "granisetron, perphenazine"
+            ]
+        },
+        {
+            "id": "task180-bcdde9881426455eb1bb9a348a2346e5",
+            "input": "After three weekly doses of epoetin alfa 40,000 U , a dose of 120,000 U can be administered safely once every 3 weeks without increasing transfusion needs or sacrificing QOL .",
+            "output": [
+                "epoetin alfa"
+            ]
+        },
+        {
+            "id": "task180-22807ace4fea4089b0058f968864e5c3",
+            "input": "However , to our knowledge , there have been no studies using all these measures together as an adjuvant antidepressant strategy .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-fb13ed9c71524d16bfbeef2ccf799542",
+            "input": "Accordingly , the current study examined within-person covariation between time-varying abstinence and depressive symptom in a multilevel model ( MLM ) , which allowed for transitions between smoking statuses within a participant .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task180-11545541370e486d90e11ee7ba8774eb",
+            "input": "Internal stenting is an integral part of endopyelotomy .",
+            "output": [
+                "stenting"
+            ]
+        }
+    ],
+    "Instance License": [
+        "Unknown"
+    ]
+}

Information_extraction/task3_outcome_extraction.json

@@ -0,0 +1,366 @@
+{
+    "Contributors": [
+        "Pegah Alipoormolabashi"
+    ],
+    "Source": [
+        "pico"
+    ],
+    "URL": [
+        "https://github.com/Markus-Zlabinger/pico-annotation"
+    ],
+    "Categories": [
+        "Information Extraction"
+    ],
+    "Reasoning": [],
+    "Definition": [
+        "In medical studies, treatments are tested within a group of study participants. To determine if a new treatment works, various outcomes are measured in the people who take part in the study. You will be given a sentence of a study report in which your task is to list the phrases that give information about the outcomes of the study. You should list the phrases in the same order that they appear in the text, separated by commas. If no information about the outcome is mentioned, just answer with: \"not found\".\n Outcomes contain: outcomes measured in patients: like blood sugar,\n outcomes regarding the intervention: like effectiveness, costs\n the score on a medical test or questionnaire,\n positive or negative events in the patient groups: like quitting smoking, or adverse reactions.\n Do not mention numbers or results, interpretations of outcomes, outcome mentions without relevant information."
+    ],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Academical Papers",
+        "Clinical Trials and Controlled Trials"
+    ],
+    "Positive Examples": [
+        {
+            "input": " Effects of 12 weeks' treatment with a proton pump inhibitor on insulin secretion, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes ",
+            "output": "insulin secretion, glucose metabolism and markers of cardiovascular risk",
+            "explanation": "The study is measuring effects of a treatment on several outcomes, which are: insulin secretion, glucose metabolism and markers of cardiovascular risk."
+        },
+        {
+            "input": "There were no serious adverse device effects.",
+            "output": "no serious adverse device effects",
+            "explanation": "Any mention of not-seen effects counts as an outcome."
+        },
+        {
+            "input": " The primary outcome measures were the score on the Irritability subscale of the Aberrant Behavior Checklist and the rating on the Clinical Global Impressions - Improvement (CGI-I) scale at eight weeks. ",
+            "output": "score on the Irritability subscale of the Aberrant Behavior Checklist and the rating on the Clinical Global Impressions - Improvement (CGI-I) scale",
+            "explanation": "All the measured scores are correctly listed in this answer."
+        }
+    ],
+    "Negative Examples": [
+        {
+            "input": "Secondary end points included change in upper-limb measures (including the Fugl-Meyer Assessment-Upper Extremity).",
+            "output": "change in upper-limb measures, Fugl-Meyer Assessment-Upper Extremity",
+            "explanation": "The upper-limb measures are correctly mentioned, but the words \"change in\" should not be included, as they're measured results."
+        },
+        {
+            "input": "More early-stage cancer (stages I and II, 54 vs. 10) were found in the screening group than in the control group.",
+            "output": "early-stage cancer, stages I and II, 54 vs. 10",
+            "explanation": "The information about number of cases in each stage is an example of numbers and measurements that shouldn't be included in the output."
+        }
+    ],
+    "Instances": [
+        {
+            "id": "task181-b6b9cc59fa1144a2ae4adfaf05be19b7",
+            "input": "Under Fluoxetine , mPFC activation was up-regulated and normalized in ASD boys relative to controls , but down-regulated in ADHD boys relative to placebo , which was concomitant with worse task performance in ADHD .",
+            "output": [
+                "mPFC activation, task performance"
+            ]
+        },
+        {
+            "id": "task181-660afac74e1a4144aefc361cacfe5dad",
+            "input": "We conclude that granisetron is a better anti-emetic than perphenazine for the long-term prevention of post-operative vomiting in children undergoing general anaesthesia for tonsillectomy .",
+            "output": [
+                "prevention of post-operative vomiting"
+            ]
+        },
+        {
+            "id": "task181-b92bd0e8930a479092c5f3675e8f1dfb",
+            "input": "One case of unsubstantiated acute rheumatic fever occurred after 7 days of amoxicillin .",
+            "output": [
+                "acute rheumatic"
+            ]
+        },
+        {
+            "id": "task181-f2e2fdd2d65e4eedaf5689d406671512",
+            "input": "Costs/QALY gained discounted at 3 % were $ 205,186 using the QWB and $ 32,643 using the CHRD .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-d6d84adef4d748a2a45078bf92625fef",
+            "input": "Calcium solubility and absorption across Caco-2 cells were studied after the in vitro digestion of the diets .",
+            "output": [
+                "absorption"
+            ]
+        },
+        {
+            "id": "task181-c52df3ee2be54a398d7c4bd65b599615",
+            "input": "Influence of diets rich in Maillard reaction products on calcium bioavailability .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-f9b50d8667b845a6a1c50339745573fa",
+            "input": "Prior adjuvant chemotherapy was permitted .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-ad0425160e8b401eab48421f77e4ad45",
+            "input": "Depressive patients are able to follow prescribed lifestyle recommendations in the short-term .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-a1b4e2b22e77474e89085a58da314dd2",
+            "input": "The influence of injections of Amidotrizoate and Iopromide into the left coronary artery on global myocardial perfusion and function ( pressures in the left ventricle , heart rate ) as well as excitation formation and transmission was studied in 16 patients with ischaemic heart disease .",
+            "output": [
+                "global myocardial perfusion and function ( pressures in the left ventricle , heart rate, excitation formation, transmission"
+            ]
+        },
+        {
+            "id": "task181-be54c87829a840cbbd6a3d4ddeaacb6f",
+            "input": "These 22 patients constituted the control group of a controlled trial and received standard outpatient clinic treatment during follow-up .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-99ca02a337044cbd88bda6dc0c590196",
+            "input": "Patients could not have had prior chemotherapy for metastatic disease .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-5827a79a4ea24d2f8204521bce20799c",
+            "input": "Comparisons with the cyclophosphamide-doxorubicin-5-fluorouracil arm will not be addressed .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-fcfedc8932dc4df9abf5e65904fdd5ae",
+            "input": "Children with parent-reported ASD had higher levels of health care office visits and prescription drug use compared with children without ASD ( P < .05 ) .",
+            "output": [
+                "levels of health care office visits, prescription drug use"
+            ]
+        },
+        {
+            "id": "task181-7b1a9e5c12e844b4a55e63ca32eeb7c7",
+            "input": "Short-term phasic activity was only found in 13 out of 40 of the normal infants ( 32.5 % ) .",
+            "output": [
+                "phasic activity"
+            ]
+        },
+        {
+            "id": "task181-7c675b2ed3c449769cf8ab917b2ccf60",
+            "input": "Group 1 received a weekly session of posterior tibial nerve stimulation for 12 weeks and group 2 was the placebo group .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-774950e6c3fd439588a89a655407d28b",
+            "input": "Only deoxypyridinoline values were significantly lower after consumption of the BD ( 13.0 +/- 1.1 compared to 18.3 +/- 2.1 nM/Mm Cr in the WD ) , possibly indicative of less efficient bone turnover during this period .",
+            "output": [
+                "deoxypyridinoline, bone turnover"
+            ]
+        },
+        {
+            "id": "task181-68a7c59ab2e04e318983f4184d60e391",
+            "input": "The results suggest that the use of PMRT could enhance quality of life and decrease state anxiety in patients after stoma surgery .",
+            "output": [
+                "quality of life, state anxiety"
+            ]
+        },
+        {
+            "id": "task181-0d279aa13ebc443a9b8b2ee194eaa2fa",
+            "input": "Interventions were conducted 30 min daily for 5-6 weeks .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-e0a60203a30c4d81a6befb0e1a2f7e15",
+            "input": "There were also no differences in manual muscle testing sum scores , activity scale scores and patients ' own assessments after 48 weeks of treatment .",
+            "output": [
+                "manual muscle testing sum scores, activity scale scores, patients ' own assessments"
+            ]
+        },
+        {
+            "id": "task181-e2cf137ad96a4c97ac77fd4a6aa5a094",
+            "input": "However , transfusion rate , presence of hepatomegaly , splenomegaly , and jaundice was similar .",
+            "output": [
+                "transfusion rate, hepatomegaly, splenomegaly, jaundice"
+            ]
+        },
+        {
+            "id": "task181-91e4da925405482a86852c2f40e94479",
+            "input": "Three hundred sixty-five patients were enrolled .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-5f8df641d10341488507af682b4cd162",
+            "input": "If so , this would be a great support for doctors who might systematically recommend these simple and costless measures , especially in primary care .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-174c2bbb0a094cf08d9be77a36021bea",
+            "input": "Relative to children in the wait-list group , program participants showed greater improvements in social skills over the course of the intervention , as indicated by parent-report measures .",
+            "output": [
+                "social skills"
+            ]
+        },
+        {
+            "id": "task181-f397803081c7484596609ab95c11305b",
+            "input": "Hence , we hypothesize that specific airway resistance changes ( \u0394sRAW ) should better characterize the acute response to bronchodilators .",
+            "output": [
+                "airway resistance changes ( \u0394sRAW"
+            ]
+        },
+        {
+            "id": "task181-6be7c34457d44d2aae095c9b8a8545b3",
+            "input": "We investigated whether 13 participants with ASD ( age 7 ; 03-22 ; 03 ) and 13 age-matched typically developing ( TD ) controls could comprehend lexicalized conceptual metaphors ( e.g. , Susan is a warm person ) and novel ones ( e.g. , Susan is a toasty person ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-a56c014af9e641e0a054df3d539e862b",
+            "input": "Randomized controlled study of chemoimmunotherapy with bestatin of acute nonlymphocytic leukemia in adults .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-00f7a9feeca443dba41ea8642d982a43",
+            "input": "Forty-nine children with AS were recruited to participate and randomly assigned to intervention ( n = 26 ) or wait-list control ( n = 23 ) conditions .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-a0ad3556ddad4a45816ca1c41f8fb899",
+            "input": "Observed medication and weekend diary cards were used to monitor adherence .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-3642ba2f6ecb422bbf9f53b3c83a712d",
+            "input": "Use of health care facilities was assessed from diaries/questionnaires and Medicare reimbursement rates used to estimate costs .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-872fcc407c5b4bddab2900ae4e64a409",
+            "input": "In 78 children known to be infected with Ascaris at baseline , the rate of weight gain was 21 per cent greater in children treated with levamisole than in those receiving placebo ( p = .03 ) .",
+            "output": [
+                "weight gain"
+            ]
+        },
+        {
+            "id": "task181-6325c79c66f245a1948b5b3edd34ecac",
+            "input": "Overall , 13 patients ( 46.4 % ) had detrusor overactivity and 14 ( 50 % ) had decreased bladder capacity .",
+            "output": [
+                "detrusor overactivity, bladder capacity"
+            ]
+        },
+        {
+            "id": "task181-88a93544f3ea44549d2830a24e2b92e0",
+            "input": "In patients with neutrophil counts of > 0.1 x 10 ( 9 ) /L lasting for more than 4 weeks , the frequency of infection in the fluconazole group ( 5 of 9 patients ) was significantly higher than in the itraconazole group ( 0 of 7 patients ; P = .03 ) .",
+            "output": [
+                "frequency of infection"
+            ]
+        },
+        {
+            "id": "task181-61f6dd4c233943c1a641eb98a6ac63cc",
+            "input": "No significant differences , within and between groups , were observed in the exercise-induced increase in the ratios para- and ortho-hydroxyantipyrine to antipyrine .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-0e571027c3ad402eac59e037eef1f9dc",
+            "input": "Age-matched boys with ADHD ( 15 ) , ASD ( 18 ) , and controls ( 21 ) were compared with functional magnetic resonance imaging ( fMRI ) during a reversal task .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-b966d8e535214bcfab19f7807a69aa51",
+            "input": "This 7-week program included a computer game , small group sessions , parent training sessions and teacher handouts .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-aa5d3b6da4d4484885016d4d791a5bbb",
+            "input": "The patients were randomised into a control group ( n = 10 ) and an experimental group ( n = 8 ) .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-02ed1112902e4c7eaff28cb2c99831d9",
+            "input": "To consider the impact on primary care patient outcomes of using both a screener to determine elevated anxiety levels among patients with previously undetected anxiety and a physician intervention to inform physicians of their patients ' conditions .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-be619ba3e04f49ad88a3012d30a053e2",
+            "input": "A persistent phasic activity pattern was found in 19 of the 21 patients , high frequency phasic activity in 11 of the 21 patients .",
+            "output": [
+                "phasic activity, phasic"
+            ]
+        },
+        {
+            "id": "task181-517cc6f8524a4005803c89fe11122459",
+            "input": "In a prospective , randomized , double-blind study , 90 paediatric patients , ASA I , aged 4-10 years , received granisetron 40 mg kg-1 or perphenazine 70 mg kg-1 ( n = 45 each ) intravenously immediately after an inhalation induction of anaesthesia .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-3926152d20b8400e8a1b5d374338ff8e",
+            "input": "After three weekly doses of epoetin alfa 40,000 U , a dose of 120,000 U can be administered safely once every 3 weeks without increasing transfusion needs or sacrificing QOL .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-1b85989710174167807d1dd176f01fab",
+            "input": "However , to our knowledge , there have been no studies using all these measures together as an adjuvant antidepressant strategy .",
+            "output": [
+                "not found"
+            ]
+        },
+        {
+            "id": "task181-5eb927181cb44fe9964ad7117653f82f",
+            "input": "Accordingly , the current study examined within-person covariation between time-varying abstinence and depressive symptom in a multilevel model ( MLM ) , which allowed for transitions between smoking statuses within a participant .",
+            "output": [
+                "depressive symptom"
+            ]
+        },
+        {
+            "id": "task181-5ffc877487054e8d875578021fb8018b",
+            "input": "Internal stenting is an integral part of endopyelotomy .",
+            "output": [
+                "not found"
+            ]
+        }
+    ],
+    "Instance License": [
+        "Unknown"
+    ]
+}

Information_extraction/task74_pmc_patient_case_report_basic_information_extraction.json

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:abebfdb544a4e9e81647fe2c7181cd05d8095505cfb71e77d115ac42bffec5c2
+size 42782661

MCQA/task61_rumedbench_question_answering.jsonl

@@ -0,0 +1,1052 @@
+{
+    "Contributors": "Pavel Blinov",
+    "Source": "RuMedBench",
+    "URL": "https://github.com/pavel-blinov/RuMedBench/tree/main/data/RuMedDaNet",
+    "Categories": [
+        "Question Answering"
+    ],
+    "Definition": [
+        "Given a question and a list of options, select the correct answer from the options directly."
+    ],
+    "Reasoning": [],
+    "Input_language": [
+        "Russian"
+    ],
+    "Output_language": [
+        "Russian"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Public Health"
+    ],
+    "Positive Examples": [],
+    "Negative Examples": [],
+    "Instances": [
+        {
+            "input": "Вопрос: Противокашлевое действие бутамирата цитрата обусловлено главным образом воздействием на кашлевой центр в мозге?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Нимесулид активно ингибирует ЦОГ-1?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Гвайфенезин - это вещество с противотревожным эффектом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Золедроновая кислота не влияет на образование и рост новых сосудов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Распределение подклассов иммуноглобулина G в этом препарате сходно с их естественным соотношением в организме?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Фозиноприл уменьшает концентрацию ионов калия?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Хондроитина сульфат оказывает восстанавливающее действие на костную и хрящевую ткани?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Трифосаденин принимают перорально?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Галактоземия относится к наследственным заболеваниям?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Инсульт случается при нарушении поступления крови к сердцу?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Китрил избирательно блокирует 5-НТ3 рецепторы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Никорандил вызывает сокращение сосудов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Итоприда гидрохлорид является антагонистом D2-дофаминовых рецепторов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Источником фолиевой кислоты для человека является только биосинтез микрофлорой кишечника?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Заболевание часто приводит к пониженому артериальному давлению?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Иммунобластный лимфаденит является следствием отёка лёгких?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Возбудителем заболевания является гемолитический стрептококк?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Функция сердечного выброса у больных хронической сердечной недостаточностью увеличена?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Пясть представлена трубчатыми костями?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Гипоталамус является высшим центром координации движений?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Прообразом кости является соединительная ткань?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Разветвления бронхиального дерева заканчиваются капиллярами?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Копчик составлен из рудиментарных позвонков?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Гортань состоит из костных элементов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Заболевание связано с дефектом тромбоцитов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Заболевание вызывается инфекционным возбудителем?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Нормальное функционирование мерцательного эпителия усиливает сопротивляемость слизистой оболочки носовой полости и придаточных пазух к болезнетворным микроорганизмам?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Структум уменьшает подвижность пораженных суставов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Можно ли утверждать, что подавляющая часть клеток, подвергшихся облучению гибнет в результате нарушений в процессах митоза?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Увеличивает ли всасываемость плохо растворимых препаратов ускорение моторики желудочно-кишечного тракта?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Аллергия на пищевой белок может быть взаимосвязана с денатурацией кишечной слизи бактериями?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: На начальной стадии болезни отмечается потеря сознания?\nВарианты: A: да\tB: нет\t",
+            "output": "Пра��ильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Деконгестанты - это препараты для устранения отека и гиперемии слизистой оболочки носа?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Каберголин получают из спорыньи?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Феназепам может быть прописан при тяжёлых случаях бессонницы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Для заболеваниях характерно появление фистул?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Настой обладает мочегонным эффектом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Данная вакцина содержит только поверхностные антигены вируса гриппа?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Признаком заболевания является присутствие в костном мозге изменённых эритрокариоцитов — мегалобластов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При гидронефрозе боли появляются с первых дней заболевания?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ишемический инсульт может быть причиной острой амнезии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Синусовая брадикардия характеризуется повышенной частотой сердечных сокращений?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Амилолитические ферменты входят в состав поджелудочного сока?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: В организме человека витамин биотин вырабатывается надпочечниками?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Причиной воспалительного процесса в желчном пузыре может быть и не инфекция?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Характерные признаки пороков сердца всегда постоянны?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Препарат хлорпротиксен относится к группе нейролептиков?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Данная анемия возникает при избыточном содержании фолиевой кислоты?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сочетание иксазомиба и леналидомида усиливает цитотоксическое действие на раковые клетки миеломы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Во��рос: Целекоксиб снижает скорость клубочковой фильтрации?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Комбинированные оральные контрацептивы снижают обильность кровотечений?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Арипипразол характеризуется умеренной аффинностью к м-холинорецепторам?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Это комбинированный препарат для улучшения работы ЖКТ?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Салметерол не ингибирует высвобождение гистамина в тканях легких?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ацетил-КоА необходим для образования лимонной кислоты?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При лобном предлежание плода нет рисков при родах?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Способны ли органы чувств обрабатывать сигналы из окружающей среды?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Приводит ли уменьшение сосудистой проницаемости к возникновению синдрома острого повреждения легких?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Амлодипин применяется для лечения людей с сердечно-сосудистыми заболеваниями?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Вещество образует ионную связь с сериновым участком желудочной и панкреатической липаз?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Существует ли вакцина против гепатита В?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Диацереин - препарат для внутривенного введения?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Хронический панкреатит является причиной поздней диагностики целиакии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Спондилёз возникает в преимущественно детском возрасте?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ибупрофен оказывает действие разжижающее кровь?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Шалфей является лекарственным монопрепаратом из группы антибиотиков?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Низкое насыщение крови кислородом может стать причиной обморока?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Краснуха передаётся человеку от животных?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Нитроглицерин снимает болевые симптомы при стенокардии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Менингококки устойчивы во внешней среде?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Окисление гипоксантина до ксантина и окисление ксантина до мочевой кислоты это стадии пуринового обмена?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Срок жизни тромбоцитов составляет 7 - 10 часов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сахарный диабет может быть причиной хронической почечной недостаточности?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При данном заболевании требуется срочное оперативное лечение?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Структурно-функциональной единицей печени являются дольки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Предсердия выбрасывают кровь в артерии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: По форме альвеолы напоминают пузырьки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Печень является местом образования вторичной мочи?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Африн вводится в нос?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Антиагреганты - это лекарственные средства, препятствующие свертыванию крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ионизирующее излучение может стать причиной лейкоза?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Для поноса характерен сухой и твёрдый калл?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При сильном волнении вкусовые ощущения человека могут быть ослаблены?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При денатурации белков отмечается изменение их первичной структуры?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: В пенетрации участвуют сперматозоид и яйцеклетка?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Бактерии эхинококка являются возбудителями микробной экземы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При применении тропикамида возможно повышение внутриглазного давления?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Перекись водорода и бактериоцины угнетают развитие ацидофильных лактобактерий?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Терапия при заболевании направлена на то, чтобы уменьшить симптомы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Сходство между средним диаметром пуповины и массой тела новорожденного ребенка является статистически недостоверным?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Вирус гриппа поражает дыхательные пути?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Во время болезни отмечается сильный кашель с обильным выделением мокроты?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Заболевание связано с крайне пониженным содержанием нейтрофилов в крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Состояние характеризуется вялостью и заторможенностью пациента?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Синдром сухого глаза может выражаться в компенсаторном слезотечении?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Бисопролол обладает мембраностабилизирующим действием?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Вирус разносится по организму с кровотоком?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Вирус вызывающий это заболевание высоко заразен?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Является ли пантовигар комбинированным препаратом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Хлоргексидин подавляет активность лактобацилл?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Являются ли желчные кислоты активаторами панкреатической липазы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Губчатую почку необходимо всегда лечить?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Биматопрост это офтальмологический препарат?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Бензоила пероксид активен только в отношении Propionibacterium acnes?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Компонент положительно влияет на клетки печени?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Этот изотонический раствор способствует сокращению объёма выделяемой мочи?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: В мышцах происходит расщепление органических веществ?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Всего в глотке семнадцать отверстий?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Тестикулярная ткань поражается при первичном гипогонадизме?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Прионный белок образуется в организме только в случае заболевания?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Нарушение липидного обмена может быть причиной гипертонической болезни?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Белки обладают термостабильными свойстваими?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Препарат обладает слабым противовоспалительным действием?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Препарат апилак вырабатывают из коровьего молока?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Апоптоз может происходить под влиянием вирусной инфекции?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Наружная часть решётчатой кости называется петуший гребень?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Белки криптохромы часто встречаются у эукариотов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Синартрозные суставы обладают максимальной подвижностью?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ацетилсалициловая кислота используется как антиагрегант?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Бисакодил — это слабительное средство на основе листьев сенны?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Аммиак оказывает токсическое действие на ткани головного мозга человека?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При остром панкреатите преобразование зимогенов в активные формы замедленно?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Мошонка относиться к наружным половым органам?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Передвижение мочи по мочеточнику происходит под действием силы тяжести?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Приведено описание ядов насекомых?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Болезнь возникает как следствие травматического поражения лёгких?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Может ли развиться желтуха при переливании крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Женский и мужской таз практически одинаковые по строению?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Процесс фосфорилирования запускается взаимодействием с тимидинкиназами?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Одно из действий препарата подавление пролиферации гепатоцитов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Рабепразол сокращает выделение желудочного сока?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Этамиван способствует сужению сосудов и замедлению доставки глюкозы в головной мозг?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Блокировка препаратом циклооксигеназы ослабляет болевые симптомы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Толтеродин способствует повышению слюноотделения?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Лекарственное средство воздействует на клетки печени?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Распределение подклассов IgG в препарате равономерное?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Волоски волосковых клеток соприкасаются с текториальной мембраной?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Количество тигроида в нервных клетках всегда постоянно?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Метотрексат обладает как противовоспалительным так и иммуносупрессивным действием?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Амисульприд связывается с холинергическими рецепторами?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Препарат подавляет синтез соляной кислоты в желудке?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Препарат воздействует на белые кровяные клетки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Отмечается увеличение шейных лимфатических узлов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Пневмококковые бактерии защищают организм от менингита?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ацетилхолин необходим для функционирования нервной системы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Заболевания этой группы приводят к тяжёлым структурно-функциональным нарушениям печени?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Заболевание вызывает структурные изменения печени?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Для этой болезни характерно резкое повышение температуры тела?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Пентоксифиллин-СЗ способен улучшать нарушенную деформированность эритроцитов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Лоперамид способствует снижению тонуса анального сфинктера?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Коллаген входит в состав зубов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Эсциталопрам является селективным ингибитором обратного захвата норадреналина?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Препарат может использоваться при отравлении солями тяжелых металлов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Мебеверин способствует наступлению гипотонуса гладкомышечных клеток ЖКТ?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Человек может задохнуться от последствий бутулизма?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Ребенку, у которого 8 балов требуется срочная помощь?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сегментированное строение позвоночника является отличительным признаком всех позвоно��ных животных?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Ретикулярная формация относится к рудиментарным органам человека?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Начало болезни характеризуется повышением температуры?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Тремор относится к сознательно выполняемым управляемым движениям?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Отвращение ко вкусу и запаху спиртных напитков объясняется повышенной концентрацией ацетальдегида?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Действие парнапарина натрия на фактор IIа значительно сильнее, чем на фактор Ха?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Полулунная кость это одна из костей запястья?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Изнутри альвеолы покрыты веществом пуллулан?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Нафтидрофурил селективно действует на 5НТ 2 -рецепторы тромбоцитов и сосудов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При применении эстриола наблюдаются кровотечения отмены в постменопаузе?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: В последнее время наблюдается рост числа пациентов с диагнозом Артериальная аневризма аорты ?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Кожный зуд при этом заболевании является возможным, но незнаначительным симптомом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Инфекция поражает органы мочеполовой системы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Заболевание связано с кожей головы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Троспия хлорид относится к холинолитическием средствам?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Препарат замедляет обмен нуклеиновых кислот?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Бетакаротен применяют для защиты кожи от вредного воздействия УФ-лучей?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Гипотензивный эффект этого препарата длится до 3 – 6 недель после завершения регулярного приема препарата?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Цетиризин - это противоаллергическое средство?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: После начала приёма дегареликса наблюдается симптоматическое обострение?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Адреномиметики используются при инфартке миокарда?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Киста в почке всегда является острым и опасным состоянием?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При сотрясении у больного наблюдается нарушение сознания?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Водно-электролитный состав при почечной недостаточности остаётся в норме?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Слабость венозных клапанов и варикоз, взаимосвязанные явления?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Вагинизм характеризуется непроизвольным сокращением лицевых мышц?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ключица соединяет рукоятку грудины с акромионом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: У мужчин и женщин полость брюшины является замкнутой?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Может ли чувство тоски и уныния быть связано с субпороговой болью?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Образование доминанты родов во время беременности - это скорее исключение, чем норма. Верно ли это утверждение?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Цитостатические средства и глюкокортикоиды могут применяться при лечении солитарной миеломы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Пневмонии при септицемии характеризуются большой выраженностью клинических признаков?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Паразит приводит к язвам кишечника?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Заболевание встречается только у девочек подросткового возраста?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Можно выделить 2 вида артериальной гипотензии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Болезнь приводит к воспалению трахеи?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Цитомегаловирус поражает слизистые оболочки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Технология ОРСАВ применяются только в условиях кардиоплегии?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Спинной мозг начинается от головного мозга?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Щитовидная железа расположена в забрюшинном пространстве?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Больным гемофилией проводят заместительную терапию?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Гемофилия поражает преимущественно женщин?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Утверждается, что достаточно сильные раздражители способны вызвать возникновение боли в любых рецепторах, так ли это?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Любые химические вещества способны вызывать возбуждение хемоноцецепторов, не так ли?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Семаглутид можно применять 1 раз в неделю благодаря продленному T 1/2 около 1 недели?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Сульпирид действует на дофаминергические рецепторы лимбической системы незначительно?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При лимфангите число лейкоцитов в единице крови увеличено?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: В первую очередь заболевание поражает сердце и лёгкие?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Глицират индуцирует выработку интерферонов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Фозиноприлат входит в состав препарата фозиноприл?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Лейкемоидные реакции относятся к болезням системы крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Эндометрит может случиться при попадании бактерий кишечной палочки в желудок?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Щитовидный хрящ соединён с подъязычной костью?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Яйцеклетка попадает в маточную трубу через протоки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Ингибиторы протонной помпы могут влиять на концентрацию хромогранина А?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Аспаркам демонстрирует сильный антиаритмический эффект?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Лактобактерин действенен в отношении стафилококковых бактерий?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Вещество оказывает действие угнетающее дыхательный центр?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Гвайфенезин стимулирует выделение секрета из бронхиальных желез?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Итоприд активирует высвобождение ацетилхолина и его разрушение?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Средство способствует расслаблению гладкой мускулатуры бронхов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Препарат способствует росту и агрегации кристаллов кальциевых солей в моче?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: В большей степени мелоксикам действует на ЦОГ-2?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Этот препарат провоцирует повторную гиперсекрецию соляной кислоты?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сулодексид снижает уровень триглицеридов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Андрогены образуются в органах-мишенях?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Приём кокаина временно обостряет восприятие окружающего мира?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Заражение трихофитией происходит половым путём?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Во время менструального цикла происходит выход яйцеклетки?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: С возрастом у мужчин наступает менопауза?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Орлистат действует на ферменты, расщепляющие триглицериды в желудочно-кишечном тракте?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Мореназал способствует затруднению дыхания?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: В описанном случае рака пищевода метастазы были выявлены уже при посмертной гистологической диагностике?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Основным методом лечения поверхностной формы заболевания является цистэктомия?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Толстая кишка отделена от тонкой илеоцекальным клапаном?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Главным компонентом синовиальной жидкости является гепариновая кислота?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Эндоскопические методики позволяют диагностировать лимфоаденопатию?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: В костном мозге уменьшено число мегакариоцитов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При заболевании поражается опорно-двигательный аппарат?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При хронических отравлениях происходит однократное воздействие токсических веществ?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: 0,9% раствор натрия хлорида является изотоничным раствором?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: ИРС 19 - это препарат для местного иммунного ответа на слизистой оболочке ротовой полости?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Плеврит всегда появляется как осложнение других заболеваний?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: При ановуляции происходит разрыв фолликула яичника и выброс яйцеклетки в брюшную полость?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сорбитол накапливается в виде гликогена?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Эфирные масла растений не могут оказывать бактерицидное действие?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Действительно ли такие проявления синдрома Марфана как \"паучьи пальцы\" и подвывих хрусталика являются примером плейотропии генов?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Привильно ли то, что при заболеваниях сердечно-сосудистой системы абсолютно противопоказан бег в любых его проявлениях?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Дискинезии пищеварительного тракта затрагивают органы пищеварения с гладкой мускулатурой?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Пациент в вегетативном состоянии способен самостоятельно передвигаться?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Может ли избирательный дефицит IgG никак не отражаться на общем содержании IgG в крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Так ли, что начальное восприятие сигналов внутренней среды происходит за счет трансформации энергии раздражителей в химические импульсы?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Поражение артерий при данном заболевании сопровождается воспалительным процессом?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Синдром мальабсорбции это причина повышенной концентрации железа в крови?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: Сальник является одним из мест накопления жировой ткани?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: В позвоночном канале расположены спинномозговые нервы и сосуды?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: При заболевании отмечается тремор рук?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Описанная болезнь называется межпозвоночный диск?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        },
+        {
+            "input": "Вопрос: ПАМБА обладает кровоостанавливающим действием за счет ингибирования фибринолиза?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: A: да"
+        },
+        {
+            "input": "Вопрос: Этот препарат снижает тонус скелетной мускулатуры?\nВарианты: A: да\tB: нет\t",
+            "output": "Правильные ответ: B: нет"
+        }
+    ]
+}

Text_summarization/task114_medqsum_text_summurization.json

@@ -0,0 +1,429 @@
+{
+    "Contributors": "MeQSum",
+    "Source": "MeQSum",
+    "URL": "https://github.com/abachaa/MeQSum",
+    "Categories": [
+        "Text Summarization"
+    ],
+    "Definition": [
+        "You will be given a long medical question. Your task is to summarize the consumer health question."
+    ],
+    "Reasoning": [],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Public Health",
+        "Heathcare"
+    ],
+    "Positive Examples": [],
+    "Negative Examples": [],
+    "Instances": [
+        {
+            "input": "SUBJECT: just a question\nMESSAGE: hi..just wanna ask... 1.how the aspirin can affect the ear? 2. what is the cause of suddenly ringging in the ear? isn't dangerous? tq.. :)",
+            "output": "What causes ringing in the ear, and can aspirin affect the ear?"
+        },
+        {
+            "input": "Dear Doc,\nI am now turning 40years in November and all my life I have desired\nmiserably for a divine intervention to restore my smell sense so that I can\nfully appreciate and participate in this one life on earth. I truly wish to\nbe a part of your research if need be because the disorder had greatly\naffected my life. If you already have medical drugs to cure and restore my\nsmell sense kindly give information on how I can acquire to benefit from\nthis. I pray that God the Creator gracefully grants me favour with this so\nthat I can enjoy the beauty of His creation in this world, with respect to\nsmell, before I depart to continue with Him in heaven. Cheers for now as I\nwait to hear from you.\n[NAME], Ms.\nSmell disorder (anosmia) patient /sufferer,\nwriting from [LOCATION]. Cell: [CONTACT], [CONTACT].",
+            "output": "What are the treatments for anosmia?"
+        },
+        {
+            "input": "SUBJECT: cosmetic leg shortening surgery\nMESSAGE: Hi,  I am a tall girl(5'8\"), who wants to undergo leg shortening sugery of 2 inches for cosmetic purpose. It would be good if I can get more information about it. I would like to know the cost of this surgery, the recovery time and the risks associated with it. How long should I stay in the hospital?  Thanks and regards",
+            "output": "Where can I find information on leg shortening surgery, including risks, cost, and recovery time?"
+        },
+        {
+            "input": "SUBJECT: ClinicalTrials.gov - Question - specific study\nMESSAGE: I am working with a Hep C   patient who needs treatment but cannot afford Tx. How can I help her get in touch with a recruiting study? There are no numbers or ways to contact a recruiting study. Sincerely, [NAME]",
+            "output": "Where can I find clinical trials on hepatitis C?"
+        },
+        {
+            "input": "SUBJECT: Laparoscopic Splenectomy\nMESSAGE: Dear Sir/Madam My brother [NAME] is diagnosed ITP. His doctor advises Laparoscopic Splenectomy for him. Can you please mail me detail and cost of this surgery. His Platletts count is decreased to 12 and his doctors giving him Injection Mebthera today to increase plattlets count. We are form [LOCATION], [LOCATION]. Please mail us as soon possible. Thanks & Best Regards [NAME]",
+            "output": "Where can I find information on laparoscopic splenectomy, including cost?"
+        },
+        {
+            "input": "SUBJECT: abetalipoproteimemia\nMESSAGE: hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks",
+            "output": "Where can I find information on abetalipoproteinemia, including diagnosis and treatment?"
+        },
+        {
+            "input": "hi. i'm a student that suffers from Pectus excavatum (funnel chest), and i need help to pass it. please give me some way to get the solution of this problem. waiting for your answer. please need help!",
+            "output": "What are treatments for pectus excavatum?"
+        },
+        {
+            "input": "SUBJECT: Looking for comparison FloraQ/RisaQuad\nMESSAGE: My MD instructed FloraQ.  Amazon advertises RisaQuad as comparable.\nYour site has never heard of RisaQuad.  Amazon ad doesn't tell you much.\nI checked several drugstores and can't find flora q in stock\nCan you help",
+            "output": "What are the differences between Flora Q and RisaQuad?"
+        },
+        {
+            "input": "SUBJECT: Research Report Assistance for Sudden Cardiac Arrest in Adolescence\nMESSAGE: Hello,               My name is [NAME] and I am a high school freshman at the [LOCATION] in [LOCATION]. I am doing a research report on Sudden Cardiac Arrest in Adolescence and I am contacting you to see if you could send me any articles, newsletters, brochures, research, pamphelts, or any other item(s) that you think might help me with my paper (especially any research that has been done or absolutely any information that you have on my topic). I am very interested in finding out more about this and the progress that has been made. I am mainly interested in researching about causes, symptoms, warning signs, treatment (if any), detection of it, and if it is purely genetic. I was also hoping you could help me better understand Sudden Cardiac Arrest in Adolescence. Let me thank you in advance for anything you send me via e-mail or mail. (In addition, if you have absolutely anything you can send me in the mail, please just tell me and I will gladly provide you with my address.) I hope that one day we can find eliminate Sudden Cardiac Arrest in Adolescence.  Thank you for your time and help, [NAME]",
+            "output": "Where can I find information on sudden cardiac arrest in adolescents?"
+        },
+        {
+            "input": "SUBJECT: gilberts diseases\nMESSAGE: my name is [NAME].  5days later i admitted in a hospital in treatment of viral fever.In hospital lot of tests blood,urine,ultrasound scan.In all tests my organs (lever,kidney,etc) are normal but my bilirubin Total is higher than normal. In my admission in hospital bilirubin is 3.2. Day by day my bilirubin decreased in the way of 2.8, 2.6, 2.4, 2.6, 2.5, respectevely. The other contents of blood and urine are normal at all. Hepatitis A,B,C are also negative.Today  Bilirubin direct  is 0.8. Doctor says it is Gilberts disease. Sir what can i do?. what is the reason for this?. what is your opinion sir? please reply soon .",
+            "output": "What causes gilberts syndrome and what are the treatments for it?"
+        },
+        {
+            "input": "SUBJECT: lupus an info on the diseise\nMESSAGE: Need all up date on lupus an send by mail informations on this subject..please i need more information to see if what i am exprienceing is in fact related to lupus ...thank you.",
+            "output": "Where can I find the latest information on lupus?"
+        },
+        {
+            "input": "Phobia: fear of taxidermy.\n Hello, I was wondering if there was a name for the fear of taxidermy? I often find myself having the symptoms this website describes when in the presence of something I fear deeply.",
+            "output": "Where can I find information on fear of taxidermy?"
+        },
+        {
+            "input": "spina bifida; vertbral fusion;syrinx tethered cord. can u help for treatment of these problem",
+            "output": "What are the treatments for spina bifida, vertebral fusion, and syrinx tethered cord?"
+        },
+        {
+            "input": "Regarding Gene. Hello!Can you advise me as to where I might be able to find information on the Gene and Variation:  BCMO1 rs 4889294, BCMO1 R267S rs 12934922 by chance please?  I believe it has to do with Vitamin A conversation but I cannot locate any info about it and treatment of course!  Thank you for your time and help! Gratefully,[NAME]",
+            "output": "Where can I find information on conditions caused by SNPs BCMO1 rs 4889294 and BCMO1 R267S rs 12934922, and what are the treatments for them?"
+        },
+        {
+            "input": "SUBJECT: Rubella\nMESSAGE: My grandson (4 yrs old) has contracted Rubella.  I know for sure he has had at least one of the vaccines.  They are living in Mexico right now.  Should we be worried?",
+            "output": "What is the prognosis of rubella in a child?"
+        },
+        {
+            "input": "SUBJECT: You know Diabetes Insipidus?\nMESSAGE: I was born with Diabetes Insipidus and have many problems since the cell was removed when I was 22 and ALL",
+            "output": "Where can I find information on diabetes insipidus?"
+        },
+        {
+            "input": "SUBJECT: Apraxia and Dyspraxia\nMESSAGE: What are the basic differences between apraxia and dyspraxia?  I get different answers from different sources. One suggests that apraxia is a motor coordination disability acquired due to damage, head injury, stroke or leasions in the brain whereas dyspraxia is inherited.  Another says that the difference is absence of coordination (apraxia) versus a more mild impairment (dyspraxia).  It is very confusing to try to sort it all out.  Thank you!",
+            "output": "What are the differences between apraxia and dyspraxia?"
+        },
+        {
+            "input": "SUBJECT: Ochoa syndrome\nMESSAGE: Where could I find more information about the rare disease, Ochoa syndrome. I think a sibling of mine might have it.",
+            "output": "Where can I find information on ochoa syndrome?"
+        },
+        {
+            "input": "SUBJECT: Progressive Supernuclear Palsy\nMESSAGE: What  is the best thing to do for my Dad who we r sure has psp!  Who r the best dr to treat this cease.  We believe my uncle had pep also   He recently passed away ,  I want to give my dad the best treatment available",
+            "output": "What are the treatments for progressive supranuclear palsy and how can I find physician(s) who specialize in it?"
+        },
+        {
+            "input": "Pupil Dilation.\n How often can a pupil dilation or eye fundus can be performed? For example is there a problem if I had one last week and then to have another this week? I appreciate your quick answer.  Thank you",
+            "output": "How often can pupil dilation be performed?"
+        },
+        {
+            "input": "MESSAGE: should Advair and Spiriva be used together?  It is my understanding that they are both control meds",
+            "output": "Can Advair and Spiriva be taken together?"
+        },
+        {
+            "input": "SUBJECT: Periventricular Heterotopia\nMESSAGE: I have a 10 year old boy with that syndrome and I will like to know if there someone doing reasech about it.  At the same time I will like to learn more about it. When my son was diagnose I was told he wasn't going to be able to do nothing at all. He was very weak , he learn to walk when he was 7 years. it been hard but I will do anything for my baby.",
+            "output": "Where can I find information on periventricular heterotopia, including the latest research?"
+        },
+        {
+            "input": "SUBJECT: Regarding falaria diseases\nMESSAGE: Sir, my wife has been suffering from falaria disease in her right leg for 2 years , please show/ tell me the treatment. my contact no. is [CONTACT].",
+            "output": "What are the treatments for filarial disease?"
+        },
+        {
+            "input": "SUBJECT: chemical reactions to meds.\nMESSAGE: What is the clinical name for people who have chemical reactions to medications? Is there a cure?  Thanks",
+            "output": "What are the treatments for drug reactions?"
+        },
+        {
+            "input": "SUBJECT: Sle\nMESSAGE: How much level of feritin is responsible for SLE? Adult still's disease is related with Sle? How we differ them?",
+            "output": "How is a differential diagnosis made between SLE and adult still's disease?"
+        },
+        {
+            "input": "SUBJECT: varicella  shingles\nMESSAGE: How can I determine whether or not I've had chicken pox.  If there is a test for it, what are the results of the tests I need to know that will tell me whether or not I have had chicken pox?  I want to know this to determine if I should have shingles vaccine  (Zostavax) Thank you.",
+            "output": "How do i find out if i had chickenpox?"
+        },
+        {
+            "input": "Achondroplasia research.\n Hello, We are students from [LOCATION] and we are doing a biology project of genetic diseases. We chose Achondroplasia as our disease to research. We have a few question and we are hoping you could answer them. Our questions are, can you tell if your child will have Achondroplasia when you are pregnant? When do people usually come in when they think something isn't right with their child? what are the worse cases of Achondroplasia you've ever seen? Thank you in advance.\nsincerely,\n[NAME]",
+            "output": "Where can I find information on achondroplasia, including prenatal diagnosis and prognosis?"
+        },
+        {
+            "input": "SUBJECT: about manturation cycle\nMESSAGE: My mensuration cycle is not uniform.. there are many days gap in a month. Some time the gap is more then 1month. What I have to do.",
+            "output": "What are the treatments for irregular periods?"
+        },
+        {
+            "input": "MESSAGE: I want more information on Hypertension and fibromyalgia, I seem to be getting only topics on diabetes and I do not have this.   I enjoy reading the current info.  thanks [NAME]",
+            "output": "Where can I find information on hypertension and fibromyalgia?"
+        },
+        {
+            "input": "SUBJECT: inversion of long arm chromasome7\nMESSAGE: My son has been diagnosed with inversion of long arm chromasome 7 and down syndrome . please could you give me information on the chromasome 7 please because our doctors have not yet mentioned it",
+            "output": "Where can I find information on chromosome 7?"
+        },
+        {
+            "input": "SUBJECT: lupus\nMESSAGE: Hi,  I  want to know about Lupus and its treatment. Best,  [NAME]",
+            "output": "Where can I find information on lupus and what are the treatments for it?"
+        },
+        {
+            "input": "SUBJECT: Asking about Hairy cell leukemia\nMESSAGE: I get report for my father from hospital it is saying that he have Hairy cell leukemia i am here to ask if this dissease dangerous and there is treatment for it  Also if The one who have it will live for long or not ?  My father age is 55  We discover the dissease by blood test",
+            "output": "Where can I find information on hairy cell leukemia, including treatment and prognosis?"
+        },
+        {
+            "input": "diagnosis of OI/ resources. I was writing to inquire about more information regarding the diagnosis of OI.  We have family members who are in the process of waiting for genetic testing to come back but are under allegations of child abuse.  Is there any information and / or resources that may be helpful to us? Any help is appreciated. Thank you,[NAME]",
+            "output": "How is osteogenesis imperfecta diagnosed and what are its symptoms?"
+        },
+        {
+            "input": "SUBJECT: shingles\nMESSAGE: Hi\nI had shingles a while ago on my left forehead and above my eye, not long after it started again, this time under my left breast, extremely painful and am wondering can this start again ?\nty\n[NAME]",
+            "output": "Where can I find information on recurrent shingles?"
+        },
+        {
+            "input": "SUBJECT: ODD facilities\nMESSAGE: Two friends of ours have an 8-year-old child with Oppositional Defiant Disorder and autism, and they are being told by a facility that they need to institutionalize him there. Our friends are heartbroken. Are there any excellent places in the country that specialize in ODD in combination with autism that might offer other options for them? Thanks for any counsel you might have.",
+            "output": "How can I find physician(s) or hospital(s) who specialize in oppositional defiant disorder and autism?"
+        },
+        {
+            "input": "SUBJECT: \"ClinicalTrials.gov - Question - general information\n\"\nMESSAGE: Please i really need your reply and your help :( My wife has Allergy from all milk products and whenever she drinks or eats any thing contains small amount of any milk products she goes to the hospital. I have faith that there is a cure for that but i really donno what to say to her. She thinks that she will never be cured. So please can you tell me is there is any cure for milk products allergy, any cure? or any cure in the very near future? I will be very very very grateful if you replied, Thanks alot. :)",
+            "output": "What are the treatments for lactose intolerance and can it be cured?"
+        },
+        {
+            "input": "SUBJECT: Plantar Fasiciitis\nMESSAGE: Is it true that more likely than not that Plantar fasiciitis could be aggravated by a consistancy of weight bearing activities?    Are there other forms of aggravation? if so will you please inform me.",
+            "output": "What are the prevention and  treatments for plantar fasciitis?"
+        },
+        {
+            "input": "SUBJECT: Very high blood sugar!\nMESSAGE: I had two injections in my feet yesterday (5-22-14).  The physician said to watch my blood sugar carefully, as the injections could cause a rise in my blood count. I began having memory problems last evening after an MRI, and then this morning and at noon today (5-23-14), my count has been 427.  I have read my magazines about diabetes, pulled up several things on Medline Plus, and tried to get in touch with two of my doctors who might help.  Everyone is busy, and I totally understand.  I just need to know what, if anything, I can do to get my blood sugar down as fast as possible.  Thank you,  [NAME] [CONTACT]",
+            "output": "What are the treatments for high blood sugar?"
+        },
+        {
+            "input": "Vitamins.\n Can I take zinc and zinc citrate at the same time?",
+            "output": "Can zinc and zinc citrate be taken together?"
+        },
+        {
+            "input": "Does either of these help with skin keloids?\nWhat would help keloids?",
+            "output": "What are the treatments for skin keloids?"
+        },
+        {
+            "input": "Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?",
+            "output": "Where can I find information on the different types of leukemia, including causes, treatment, prognosis, diagnosis, symptoms, and inheritance?"
+        },
+        {
+            "input": "SUBJECT: New Hep C Virus Treatments\nMESSAGE: In 2006-2007, at the VAMC in [LOCATION], i went through the HEP C Treatment using Ribavirin and Interferon. My viral load was undetectable immediately at the BOT. I stayed on the treatment faithfully and painfully for a4 months; when at the EOT my viral load was still indictable. I was considered a success. When i came back after 6 months for a checkup, it was found my HCV had relapsed. Now I want to know what treatments are now available to me. I hear of these new wonder cures that have been approved in the past year and i want to be retreated. Please send me all the info you have on these new treatments while i wait here and die at age 45. I was exposed with the HCV virus from a tattoo while in the armed forces overseas.",
+            "output": "What new treatments are available for recurrent hepatitis C?"
+        },
+        {
+            "input": "SUBJECT: shingles\nMESSAGE: I work at the Airport and I am in contact with hundreds of people a day. I want to be sure that I am not going to expose people to Shingles. When is it safe for me to go back to work?",
+            "output": "When is shingles contagious?"
+        },
+        {
+            "input": "SUBJECT: Treatment required\nMESSAGE: I m 37 years old and i m suffer from poor hunger,loss of appetite and and no desire to eat. I have only some anxietic condition and some heart burn problem. Kindly suggest something for me to solve my problem.",
+            "output": "What are the treatments for anxiety, heartburn, and loss of appetite?"
+        },
+        {
+            "input": "SUBJECT: Negative Interaction\nMESSAGE: My question is the following : is there any negative interaction between Ginkgo and Pycnogenol. Thank very much for your attention.",
+            "output": "Are there drug interactions between ginkgo and pycnogenol?"
+        },
+        {
+            "input": "SUBJECT: RUSSEL SILVER SYNDROME\nMESSAGE: I want to know about RUSSEL SILVER SYNDROME If I ask you my little son nine month old but he look like very little I don't know anything about this symptoms please send me all information. my address [CONTACT].",
+            "output": "Where can I find information on russell-silver syndrome?"
+        },
+        {
+            "input": "Cross Eye.\n Need to fix my cross eyed",
+            "output": "How to treat crossed eyes?"
+        },
+        {
+            "input": "MESSAGE: hi my name is [NAME] I'm currently working with [LOCATION] and I was wondering  I came across some of you healthy tip fliers for HIV/Aids treatment .at the moment we have a study  going on that helps HIV positive transgender women into HIV quality care .so it would be great to have some more information on HIV/Aids treatment",
+            "output": "What are the treatments for HIV/AIDS?"
+        },
+        {
+            "input": "MESSAGE: I have had renal organ transplant surgery a year ago. What risk factos must I avoid to prevent the recurrance of ESRD and to maintain a healthy &functioning grafted kidney ?",
+            "output": "How do I care for my kidney after renal transplant?"
+        },
+        {
+            "input": "SUBJECT: oleander poisoning\nMESSAGE: If oleandor was ingested by touching the plant stems inner part and then directly eating without washing hands, how long would u exspect symptoms would start? And how severe would you say symptoms may get.",
+            "output": "When do symptoms of oleander poisoning appear after ingesting the plant, and how severe can they get?"
+        },
+        {
+            "input": "ClinicalTrials.gov - Question - general information.\n My granddaughter was born with Klippel-Tranaunay Syndrome...There is very little information about this.  We are looking for the current research and treatments available.  She is 5 months old now and her leg seems to be most affected.  We want to get her help as soon as possible to address the symptoms and treat her condition.",
+            "output": "What is the latest research on klippel-trenaunay syndrome, and what are the treatments for it?"
+        },
+        {
+            "input": "SUBJECT: spinal cord stenosos\nMESSAGE: I have acute arthritic spinal stenosis. What treatment is recommended?",
+            "output": "What are the treatments for spinal cord stenosis due to arthritis?"
+        },
+        {
+            "input": "SUBJECT: questins\nMESSAGE: i am looking for the latest evidence based practice on guidelines for assessing and treating Alcohol and Opiate withdrawal. Thanks.",
+            "output": "What are the latest evidence based treatments for alcohol and opiate withdrawal?"
+        },
+        {
+            "input": "hello\ni am looking for information related to the above (myostatin-related muscular hypertrophy) genetic condition.\ncan you direct me to a hospital or other genetic research institution that might be doing research on this genetic condition?",
+            "output": "Where can I find information on myostatin-related muscular hypertrophy, and how can I find an organization doing research on it?"
+        },
+        {
+            "input": "SUBJECT: Painful menstrual periods\nMESSAGE: My wife has suffered this . How can treat this.",
+            "output": "What are the treatments for painful menstrual periods?"
+        },
+        {
+            "input": "I have an hernia I would love to take care off it ASAP I was wondering if you guys could help me . Thanks",
+            "output": "What are the treatments for hernia?"
+        },
+        {
+            "input": "SUBJECT: ClinicalTrials.gov - Question - general information\nMESSAGE: I HAVE A BOY 16 WHO JUST GOT OUT OF A PLACE THAT GAVE HIM MEDACATION,THES ARE THE MEDS.MONTELUKAST,LORATADINE,OXCARBAPINE. WHAT DISORDER ARE THEY FOR?",
+            "output": "What are the indications for montelukast, loratadine, and oxcarbazepine?"
+        },
+        {
+            "input": "SUBJECT: LGMD\nMESSAGE: Dear Sir, i would like to bring your kind attention to a serious matter that my Mother has been suffering from LGMD so i would like to request you for any possible assistance regarding the treatment of this disease.  my email id is [CONTACT]",
+            "output": "What are the treatments for LGMD?"
+        },
+        {
+            "input": "SUBJECT: Cervical Cancer\nMESSAGE: Can a long term untreated bladder infection aid in the cause of cervical cancer? And can the fact that my mom has cervical cancer aid in my chance of getting cervical cancer?",
+            "output": "What causes cervical cancer, and is it hereditary?"
+        },
+        {
+            "input": "cant use site.\n I want to find a doctor who specializes in burning mouth syndrome and that could be in many specialities, I cannot understand how to do this on your website.",
+            "output": "How can I find physician(s) who specialize in burning mouth syndrome?"
+        },
+        {
+            "input": "Good evening, I will contact you as my [NAME] a year and a half have been diagnosed with the genetic mutation STXBP1. I would like to know if there is something in the world that can help my son. I hope you contact us as soon as possible. \nGreetings [NAME]",
+            "output": "What are the treatments for genetic mutation STXBP1?"
+        },
+        {
+            "input": "SUBJECT: please send me medical information about heart failer for care.\nMESSAGE: send me information about heart failer.",
+            "output": "What are the treatments for heart failure?"
+        },
+        {
+            "input": "Kartagener's syndrome. I am suffering from Kartagener's syndrome and wanted information from you or from Dr. [NAME]. for this syndrome. (About fertility) and if possible other symptoms. Thank you.",
+            "output": "Where can I find information on kartagener's syndrome and its symptoms, including  fertility?"
+        },
+        {
+            "input": "pierre robins syndrome. Good Morning, Just a query for you regarding the above. Is it true to saythis is caused by an abnormal chromezone and is carried by the mother and transferred to boys only. This is supposed to happen 1 in 4. The male does not carry the jene. I would appreciate your expert information please.",
+            "output": "What are the inheritance patterns for pierre robins syndrome?"
+        },
+        {
+            "input": "migraine. I want to know the treatment for FHM type of migrain . I had observed the all symptoms which are same as provided in information and additionally my father and my younger sister face the acidity problem too. they feel relief after vomiting so both of them do the same by drinking warm water containing salt.",
+            "output": "What are the treatments for familial hemiplegic migraine?"
+        },
+        {
+            "input": "SUBJECT: Obesity Questions\nMESSAGE: Hello. My name is [NAME] and I am a junior in high school. I am currently doing a research topic on obesity and was wondering if you would be able to answer a few questions. It would be greatly appreciated if you could! Thank you! 1)What/Who is to blame for obesity? 2)Do you think putting  a tax on junk food will reduce the amount of obese people? Why or why not? 3)How can we prevent obesity? 4)What are the benefits of getting 30 minutes of exercise daily and eating healthy? 5)Should the government be more involved in the help to stop obesity? Why or why not? 6)What is the number one thing we should eat less of/ cut out of our diets? (such as, fats, carbs, sugars,etc)  Thank you for your time!",
+            "output": "Where can I find information on obesity, including causes, prevention, and treatments?"
+        },
+        {
+            "input": "SUBJECT: once you open the bottle of Releev, how long is it good for?\nMESSAGE: once you open the bottle of Releev, how long is it good for?",
+            "output": "How long does releev retain its potency after opening?"
+        },
+        {
+            "input": "SUBJECT: dry maculare tetinal degeneration\nMESSAGE: my grandfather had lens implants, now he has dry macular retinal degeneration.  he can hardly see!  searching for help!",
+            "output": "What are the treatments for dry macular retinal degeneration? "
+        },
+        {
+            "input": "SUBJECT: is there any medicines for peristaltic movements?\nMESSAGE: I V[NAME] From [LOCATION] which is located at INDIA. I am a patient of less peristaltic movements which was digests the eaten food in 3 to 4 hours... In normal humans which was digests the eaten food in 2 to 3 hours...  I visited several hospitals in [LOCATION] which is located in INDIA...  When i was visited [LOCATION]\" Hospital at HYDERBAD in the year of 2010..  There Doctors has told there is no medicins for this problem..  Is  there any medicines to improve my  peristaltic movements?  Please Replay to My E-mail[CONTACT] and My Mobile Number is: [CONTACT]  Thanking You taking my request....",
+            "output": "What are the treatments for slow peristaltic movements? "
+        },
+        {
+            "input": "SUBJECT: question about ingredients\nMESSAGE: I am currently taking 20mg generic Adderall immediate release from your company. Does this medication have gluten containing ingredients? I have Celiac disease and I am very sensitive to small amounts, so I am trying to make sure this medication is safe to take.\nThank you for any and all help.\n-[NAME]",
+            "output": "What are the ingredients of  20mg generic Adderall and it is gluten free?"
+        },
+        {
+            "input": "what does it means if someone blood is light.\n I took injection this night and the nurse said my blood is light, what's does that mean. Sinfe , have been worry.",
+            "output": "Why is my blood a light red?"
+        },
+        {
+            "input": "SUBJECT: Omege 3 Acid capsule\nMESSAGE: I am currently taking Lovaza. My pharmacy, CVS, has advised me that the above, Omega 3 Acid capsule is now available as a generic alternate. My doctor has said that she is not aware of a generic for Lovaza. Who is correct?",
+            "output": "Is there a generic version of Lovaza? "
+        },
+        {
+            "input": "Factor 12 defeincy. I have factor 12 defiency, my GP has told me it is linked to aboriginal/ TSI heritage, is this correct ?    Thanks [NAME]",
+            "output": "Is factor 12 deficiency linked to aboriginal heritage?"
+        },
+        {
+            "input": "SUBJECT: fibroadenomas\nMESSAGE: i have a fibroadenomas? my question is it can remove without surgery? taking medicine is help to reduce or remove this? or if i didnt undergo operation it is safe? because surgery is expensive here at the philippines",
+            "output": "Can fibroadenoma be treated without surgery?"
+        },
+        {
+            "input": "SUBJECT: foreskin\nMESSAGE: I want to regrow my foreskin back. When will stem cell be able to regrow foreskin.",
+            "output": "Is stem cell therapy used to regrow foreskin?"
+        },
+        {
+            "input": "SUBJECT: methotrexate - gluten free?\nMESSAGE: is the injection form of methotrexate gluten free?\nthanks -",
+            "output": "Is the injection form of methotrexate gluten free?"
+        },
+        {
+            "input": "SUBJECT: Peruvian girl\nMESSAGE: Dear Sir/Madam, I am writing you on behalf of [NAME], who is very stress and with a lot of tension,looking for HELP for her daughter [NAME].  [NAME] has a complex hearth defect called Tetralogy of Fallot, she is about 7 months old and her family dont have resources to cover her treatment in order to get her welfare.  [NAME] has a very low income, lives in a rented room with her husband and her two children, in [LOCATION] - Peru. She works at [LOCATION] and she has been taking her daughter to children hospital in [LOCATION] but she cant afford the medicines and treatment that they ask for, she is looking desperately for help for her daughter.  I was wondering if you guys have any contact here in [LOCATION] of any organization, who can help [NAME]. I have been looking but cant find or never not came back to me when I asked them.  If you please know about any organization who can help us here in [LOCATION] Peru, I will really appreciate and we can make help to give [NAME] a better life :-)  I am a Health and Social care worker and work at the hospital too with the employees. Thank you very much for your time  [NAME]  [CONTACT]",
+            "output": "Which organizations provide support for Tetralogy of Fallot in Peru?"
+        },
+        {
+            "input": "SUBJECT: Heat rash\nMESSAGE: I am looking for information on heat rash.  Specifically, can it look like a red line and how it appears at it resolves.\nIf information is available, I can come to the library to read hard copy text or copy photographs.\nI can be reached through email or by calling [CONTACT].\nI appreciate all the help that may be available on this important matter.",
+            "output": "Where can I find information on heat rash, including symptoms and treatment? "
+        },
+        {
+            "input": "SUBJECT: high inner eye pressure above 21 possible glacoma\nMESSAGE: have seen inner eye pressure increase as I have begin taking Rizatriptan. I understand the med narrows blood vessels.  Can this med.  cause or effect the closed or wide angle issues with the eye lense/glacoma.",
+            "output": "Can Rizatriptan cause glaucoma?"
+        },
+        {
+            "input": "hypothyroidism.\n My doctor started me on levothyroxene 5oMCG. for 5mths.How do I know if this is  the rite dosage? Do not want to cause myself any harm by overdosing",
+            "output": "What is the normal dosage of levothyroxine for hypothyroidism?"
+        },
+        {
+            "input": "SUBJECT: theoretical question\nMESSAGE: How much time you can spend at most before a cerebral aneurysm will cause death? Sorry I'm using translator because I speak and write in Spanish if they were so kind to send me the answer to [CONTACT] Thanks.",
+            "output": "What is the prognosis of cerebral aneurysm?"
+        },
+        {
+            "input": "SUBJECT: adrenoleukodystrophy\nMESSAGE: A child I have been asked to work with has been diagnosed with this condition.I am so far unable to find info pertaining to this illness. Can you help??",
+            "output": "Where can I find information on adrenoleukodystrophy? "
+        },
+        {
+            "input": "laser hair removal treatment.\n I HAVE EXCESS HAIR GROWTH ON MY NECK AND CHIN. REASON IS MY HORMONAL IMBALANCE AND THYROID. THEY ARE BLACK HARD HAIRS. I WANT TO KNOW THAT LASER HAIR REMOVAL IS SAFE AND SATISFATORY FOR ME OR NOT? WHAT IS ITS CONSEQUENCES IN LONG TERM? WILL THE HAIR GROWTH WILL BE CONTROLLED LIFE TIME! PLEASE GUIDE ME.. ! THANKING YOU!",
+            "output": "Where can I find information on laser hair removal including long term consequences?"
+        },
+        {
+            "input": "Hey I was just wanting to know how I can try to receive stem cell treatment for spinal cord injury using the stem cells I have banked from my newborn baby's umbilical cord tissue? If u have any information please tell me, you'll be helping to save my life!",
+            "output": "How to receive stem cell treatment for spinal cord injury?"
+        },
+        {
+            "input": "SUBJECT: spg11\nMESSAGE: My 24 year old son was recently diagnosed with  spg11 after over 15 years of trying to figure out what was wrong.  We are already doing some of the common treatments.  My question is, where do we go from here to give him the best chance at life,",
+            "output": "What are the treatments and prognosis for spg11?"
+        },
+        {
+            "input": "SUBJECT: diabetes\nMESSAGE: It was really helpful after reading about type 1 diabetes but would like some more suggestions from you .my friend is 35 year old and its been 1 year of his diabetes n his sugar level is around 100 or 120 OR SO.. each time he tests his sugar level. is there ANY COMPLICATIONS? HE ALSO GO FOR EXERCISES AND BLOOD TEST EVERY 2 OR 3 MONTHS N TAKES A PROPER DIET LIKE GREEN JUICE,OLIVE OIL AND ALL. WAITING FOR YOUR FEED BACK. THANK YOU.",
+            "output": "What are the complications of type 1 diabetes?"
+        },
+        {
+            "input": "MESSAGE: I have to start applying ciclopirox to infected toes. I know u cannot use nail polish bit can I put a band aid on once the medication has dried?",
+            "output": "Can i cover ciclopirox with bandaids?"
+        },
+        {
+            "input": "About Aarskog Syndrome. hi my name is [NAME] i am 21 this year and was wondering if it is connected with server  Astigmatism as i got it in my left eye. I have a mild form of As, i have the wide peek eyes and rugby shaped and missing DNA which they have discovered in MRI scans. I was diagnosed when i was born but it still seems to be in research as we speak and ever since i turned 18 i have been doing my own research and finding others around by connecting with them on Facebook. I live in the [LOCATION] and found out there are four people that have Aarskog syndrome. thank you for your time",
+            "output": "Is Astigmatism related to Aarskog Syndrome?"
+        },
+        {
+            "input": "GERD.\n I'm a 72 year old female, and have diverticulosis,gastritis, and esophagitis.  I tried to see three different doctors today, but all were booked.  I honestly don't know what to do.  It hurts in my chest, and I can hardly talk.",
+            "output": "How to treat chest pain potentially associated with  diverticulosis, gastritis, and esophagitis?"
+        },
+        {
+            "input": "SUBJECT: Ankle Injury\nMESSAGE: I got hurt in my left leg ankle almost 5 months ago. I went to doctor, got x-ray, where no damage was found. He suggested me some pain killers and advised me to wear anklet. I have been following the instruction since then; I went to another doctor who advised me to go for physiotherapy (Short Wave Diathermy) and advised me some exercises. I have been following them too. But yet now, I have not been fully recovered from the pain. Especially when I try to walk quickly or try to put pressure with my left leg, I feel pain. I am very tensed about this. Can you please suggest me how to overcome the pain. Thanks.",
+            "output": "What are the treatments for ankle injury and pain? "
+        },
+        {
+            "input": "SUBJECT: Ankylosing Spondylitis\nMESSAGE: Hello, My name is [NAME] and i live in india. I have suffered Ankylosing Spondylitis problem since last 2 years in lower back. so plz guid me properly how to cure this problem?  Thanks [NAME]",
+            "output": "What are the treatments for Ankylosing Spondylitis?"
+        },
+        {
+            "input": "SUBJECT: Ingredients\nMESSAGE: Pleease email  me a llist of 100%, all, of the ingredients iPerioMed, .63% floride concetrate Oral rinse,, alcohol rinse.\nThank you!  [NAME]",
+            "output": "What are the ingredients of PerioMed 63% fluoride concentrated oral rinse?"
+        },
+        {
+            "input": "ARE THERE ANY SKIN CREAMS THAT HAVE POSITIVE EFFECTS ON SKIN CANCER?? \u00a0WHICH ARE THE BEST??\u00a0[CONTACT]\u00a0",
+            "output": "What are the best creams for skin cancer? "
+        },
+        {
+            "input": "asthsma.\n I have been having problems w/ shortness of breath and dizziness and stress heat. what do you think? do i have asthsma or not?",
+            "output": "What are the symptoms of asthma? "
+        },
+        {
+            "input": "ClinicalTrials.gov - Question - specific study. Do you have any more indepth information regarding pseudocholinesterace deficiency? My son 28 and myself 56 have this problem and we both have systemic muscle spasms. cramps contractions. Most seem to be caused by knots or trigger points. I assume this has something to do with this deficiency because it deals with neuro transmissions correct. Anyway we are looking for relief. The muscle relaxants help a bit but the knots do not go away and so the pain is still there at a deeper level. The doctors and neurologist have no idea. Thank you. [NAME]",
+            "output": "Where can I find information on pseudocholinesterase deficiency icluding treatment?"
+        },
+        {
+            "input": "SUBJECT: after surgery of ear drum still same problem\nMESSAGE: i got surgery for hole in my ear drum(hole was in my ear from 5 0r 6 ears but i did not know it but when i came to know i got surgery) but after  two year surgery still i have same problem. problem in listening and continuous noise like buzzing or ringing in my right ear.so sir what should i do right now? plz sir help me. buzzing in my both has been started from last 3 year.plz help me....",
+            "output": "What are the treatments for perforated eardrum?"
+        },
+        {
+            "input": "SUBJECT: ClinicalTrials.gov - Question - specific study\nMESSAGE: LOOKING FOR HELP FOR MY NEPHEW WITH GLYCOGEN STORAGE DISEASE.  HE LIVES IN VIRGINIA AND IS SUFFERING BADLY.  HE HAS BEEN HOSPITALIZED FOR SEVERE CRAMPING ABOUT 5 TIMES THIS YEAR SO FAR.  ANY GUIDANCE YOU COULD GIVE WOULD BE GREATLY APPRECIATED.",
+            "output": "What are the treatments for Glycogen storage disease?"
+        },
+        {
+            "input": "MESSAGE: I have numbness/tingling in my lower right arm from elbow to my fingers. A EMG has shown nothing abnormal. I have had this for a long time, I need help.",
+            "output": "Where can I find information and treatment for numbness and tingling in lower right arm?"
+        },
+        {
+            "input": "SUBJECT: sleep apnea\nMESSAGE: I was diagnosed with sleep apnea (prolly had it for 5 years) and I have swelling issues caused from that (it has been ruled out from everything else so the doctor thinks).  I just got my cPap machine.  I was wondering how long will it take for the swelling to go away.  Thank you!",
+            "output": "How long does swelling from sleep apnea take to heal? "
+        },
+        {
+            "input": "SUBJECT: Home resources for AMD people\nMESSAGE: What specific resources are available for an elderly male living by himself at home?  My father in law is 85 years old, lives alone and has macular degeneration.  Looking for visual aids to assist him around the house.",
+            "output": "What resources are available for elderly with age-related macular degeneration?"
+        }
+    ]
+}

Text_summarization/task85_mimic_ct_brain_summarization.json

@@ -0,0 +1,59 @@
+{
+    "Contributors": "MIMIC",
+    "Source": "MIMIC-IV",
+    "URL": "https://www.physionet.org/content/mimic-iv-note/2.2/",
+    "Categories": [
+        "Summarization"
+    ],
+    "Definition": [
+        "Summarize the CT imaging diagnostics' detailed findings for the Brain into a concise conclusion."
+    ],
+    "Reasoning": [],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Medicine",
+        "Clinical Reports",
+        "CT",
+        "Brain"
+    ],
+    "Positive Examples": [],
+    "Negative Examples": [],
+    "Instances": [
+        {
+            "input": "There is no evidence of infarct, hemorrhage, or mass.  The\nventricles, cisterns, and sulci show symmetric, age-related prominence.  There\nis no fracture.",
+            "output": "Normal for age."
+        },
+        {
+            "input": "There is no evidence of acute intracranial hemorrhage, mass, mass effect or\nlarge territorial infarction.  Prominence of the ventricles and sulci is\nlikely related to age related involutional changes.  Periventricular deep\nsubcortical white matter hypodensities are likely sequelae of chronic\nmicroangiopathy.  The basilar cisterns are patent, and there is otherwise good\npreservation of the gray-white matter differentiation.\n\nMild mucosal sinus thickening is seen involving the ethmoid air cells.  The\nremainder the visualized paranasal sinuses, mastoid air cells, and middle ear\ncavities are clear.  The globes are unremarkable.\n\nCT BRAIN PERFUSION:\nCBF <30% volume: 12 cc\nTmax >6.0s volume: 12 cc\nMismatch volume: 0 cc\nMismatch ratio: 1.0",
+            "output": "No acute intracranial abnormalities identified.  Chronic microangiopathy."
+        },
+        {
+            "input": "CT HEAD WITHOUT CONTRAST:\nThere is loss of the gray-white differentiation involving the left MCA\nvascular territory distribution, consistent with acute ischemic infarction. \nThere is mild sulcal effacement in the left frontal and parietal lobes in a\nsimilar distribution, compatible with cytotoxic edema.  There is no evidence\nof intracerebral hemorrhage or suspicious mass.  The ventricles and sulci are\nnormal in size and configuration.\n\nThere is no acute calvarial fracture. The visualized portion of the paranasal\nsinuses, mastoid air cells,and middle ear cavities are clear. The visualized\nportion of the orbits are normal.\n\nCT PERFUSION: RAPID perfusion maps demonstrate an area of increased mean\ntransit time with corresponding decreased region through blood volume,\nindicative portion of the left MCA territory.  Surrounding the score is a\nsmall number of the demonstrates preserved volume with a reduction in cerebral\nblood flow, indicating ischemic penumbra.  Per the RAPID perfusion maps, there\nis an approximate the mismatch volume of 351 mL with a mismatch ratio of 8.2. \nThere is significant motion artifact, which may artificially increased the\nmean transit time.\n\nCBF <30% Volume: 49 mL\nTmax>6.0s: 400 mL\nMismatch Volume: 351 mL\nMismatch ratio: 8.2",
+            "output": "1. There is loss of gray-white matter differentiation in the left the MCA\nvascular territory concerning for acute infarction.  There is a corresponding\ninfarct core with surrounding ischemic penumbra in the left frontal and\nparietal lobe on the perfusion imaging."
+        },
+        {
+            "input": "There has been progressive decrease in size of the bifrontal\nextra-axial collections measuring 5-mm thick on the left and 4-mm thick on the\nright today compared to 8 mm on the left and 5 mm on the right on ___. \nAs before, these collections are predominantly low in density with a higher\ndensity portion peripherally.  There is no evidence of new hemorrhage or mass.\nProminent cisterna magna is again incidentally noted.  There is no evidence of\ninterval infarct.  Osseous structures are significant only for a defect from\nthe prior burr hole decompression bilaterally.",
+            "output": "1. Continued interval decrease in size of bifrontal extra-axial collections.\n2. Status post bilateral burr hole evacuation."
+        },
+        {
+            "input": "Study is mildly degraded by motion.\n\nCT HEAD WITHOUT CONTRAST:\nThere is no evidence of there is hypoattenuation in the right temporal and\nparietal lobes with loss of gray-white matter differentiation, sulcal\neffacement, and there is also hypoattenuation along the insula and involving\nthe right caudate nucleus.  There is no hemorrhage.  In addition, there is a\nlarge intermediate attenuation structure which appears to extend from the\nright ICA terminus towards the middle cerebral artery bifurcation consistent\nwith a partially calcified aneurysm, with a pipeline flow diverting or noted\nextending from the cavernous internal carotid artery through the M1 segment on\nthe right.  This measures 3.9 x 2.6 cm.  There are prominent calcifications of\nthe bilateral carotid siphons.\n\n No hydrocephalus.  Mild prominence of the ventricle and sulci reflecting\nvolume loss is noted.\n\nThe visualized portion of the there is mild mucosal thickening in the\nmaxillary sinuses and ethmoid air cells, with sclerosis and thickening of the\nwalls of the right maxillary sinus likely reflecting the sequelae of chronic\nsinus disease.  There is deformity of the right mandibular condyle likely\nreflecting old trauma.  Poor dentition, with the remaining teeth showing\ndental caries.  The mastoid air cells,and middle ear cavities are clear. The\nvisualized portion of the orbits are unremarkable.\n\n\nCT PERFUSION: RAPID perfusion maps demonstrate perfusion defect in the right\nmiddle cerebral artery territory with quantitative values as below:\n\nCBF<30% volume: 89 mL\nTmax>6.0s volume: 264 mL\nMismatch volume: 175 mL\nMismatch ratio: 3.0",
+            "output": "1. Findings consistent with ischemia in the right middle cerebral artery\nterritory with perfusion defect as detailed above, mismatch volume of 175 mL. \nNo hemorrhage.\n2. There is a large approximately 3.9 cm calcified aneurysm likely arising\nfrom the right internal carotid artery terminus and projecting laterally\ntowards the middle cerebral artery, with a flow diverting stent in place. \nThis examination does not include a formal angiogram for assessment of stent\npatency or aneurysm patency.\n\nNOTIFICATION:\n The findings were discussed with ___, M.D. by ___, M.D.\non the telephone on ___ at 12:25 pm, 3 minutes after discovery of the\nfindings."
+        },
+        {
+            "input": "CT Head: There is no evidence of hemorrhage, mass effect, edema, or\ninfarction. The ventricles and sulci are normal in size and configuration. \nThere is age-appropriate diffuse parenchymal volume loss with commensurate\nprominence of the ventricles and sulci.  There is nonspecific periventricular\nand subcortical white matter hypodensities, likely sequela of chronic small\nvessel microangiopathy.\n\nAerosolized secretions are seen in the left posterior ethmoid air cells.  Mild\nmucosal thickening is noted in the right posterior ethmoid air cells. \nOtherwise, the remaining paranasal sinuses and mastoid air cells are clear. \nThe orbits are unremarkable.\n\nCTA head:  The major intracranial arterial vasculature is patent without\nevidence of stenosis, occlusion, or aneurysm.  There is an azygos anterior\ncerebral artery, which is a normal variant.  A fenestration is noted along the\nright A1 branch of the anterior cerebral artery, adjacent to confluence of the\nright and left A1 branches (series 4: Image 242).  A small infundibulum is\nnoted at the origin of the left internal choroidal artery.\n\nCT Perfusion:  The perfusion maps appear unremarkable.  There is no evidence\nof delayed transit time, or reduced blood volume, or reduced blood flow.\n\nCTA Neck:   The common carotid and vertebral arteries and their major branches\nare patent with no evidence of stenoses.  There is calcified atherosclerotic\nplaque in the distal common carotid artery extending to the origins of the\nright internal and external carotid arteries.  There is no evidence of right\ninternal carotid  by NASCET criteria.  There is calcified and noncalcified\nplaque at the origin of the left internal carotid artery with an approximately\n50% stenosis by NASCET criteria.\n\nAtherosclerotic calcifications are seen in the aortic arch, bilateral\nvertebral artery origins, bilateral carotid siphons, and carotid bifurcations.\nThere is a 3 vessel aortic arch.  Tiny subcentimeter hypodensities are seen in\nthe right thyroid lobe, likely thyroid nodules.  ___ College of Radiology\nguidelines do not suggest further evaluation for incidental thyroid nodules of\nthis size.  Emphysematous changes are seen in the bilateral lung apices. \nRespiratory motion artifact limits evaluation for small pulmonary nodules.",
+            "output": "1.  No evidence of infarction or hemorrhage.\n2.  50% stenosis at the origin of the left internal carotid artery.\n3. The major intracranial arterial vasculature is patent without evidence of\nstenosis, occlusion, or aneurysm.\n4.  The carotid and vertebral arteries and their major branches are patent\nwithout evidence of stenoses.\n5.  Chronic small vessel ischemic disease and age appropriate involutional\nchanges.\n6.  Emphysematous changes are incidentally seen in the bilateral lung apices."
+        },
+        {
+            "input": "CT head perfusion:\n\nRAPID analysis of perfusion images not available, as scan was performed on a\nscanner which does not contain software.\n\nOLEA analysis-these numbers are not validated and study:\nThere is decrease cerebral blood flow left MCA distribution, volume 0.6 mL.\nProlonged T-max left MCA distribution, volume 26 mm.\n\nColor maps:\nOn color maps there is no abnormality on the CBV.\nSmall area of decreased CBF left MCA distribution cortex and corona radiata M\n5 zone.\nModerate zone of prolonged T-max in the left MCA distribution, M4, M 5, M 6\nzone.\nModerate zone of prolonged T-max right MCA distribution.",
+            "output": "1. No RAPID analysis available.\n2. Visual color maps demonstrate prolonged mean transit time bilateral MCA,\nleft greater than right.  Small area of decreased cerebral blood flow left MCA\ndistribution.\n3. OLEA analysis as above, not validated in a study."
+        }
+    ]
+}

Text_summarization/task89_mimic_mri_chest_summarization.json

@@ -0,0 +1,123 @@
+{
+    "Contributors": "MIMIC",
+    "Source": "MIMIC-IV",
+    "URL": "https://www.physionet.org/content/mimic-iv-note/2.2/",
+    "Categories": [
+        "Summarization"
+    ],
+    "Definition": [
+        "Summarize the MRI imaging diagnostics' detailed findings for the Chest into a concise conclusion."
+    ],
+    "Reasoning": [],
+    "Input_language": [
+        "English"
+    ],
+    "Output_language": [
+        "English"
+    ],
+    "Instruction_language": [
+        "English"
+    ],
+    "Domains": [
+        "Medicine",
+        "Clinical Reports",
+        "MRI",
+        "Chest"
+    ],
+    "Positive Examples": [],
+    "Negative Examples": [],
+    "Instances": [
+        {
+            "input": "LUNGS: The visualized portions of the lungs do not demonstrate any obvious\nmasses, given the limitations of MRI.  There is abnormal right pleural\nthickening which enhances post gadolinium administration, concerning for\nmetastatic disease.  Associated trace right pleural effusion.\n\nVASCULATURE: Visualized portions of the thoracic aorta and pulmonary arteries\nare unremarkable.\n\nHEART AND MEDIASTINUM: There is no lower mediastinal lymphadenopathy.  No\npericardial effusion.\n\nUPPER ABDOMEN: Visualized cuts through the upper abdomen demonstrate few T2\nhyperintense foci in the liver, measuring up to 1 cm in segment 2, likely\ncysts.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: Multiple thoracic vertebral body\nmetastatic lesions are again demonstrated, involving the T2, T3, T6, T10 and\nT12 vertebral bodies.  There is abnormal enhancement extending into the\nposterior right transverse processes and ribs in the mid thoracic spine. \nThere are also foci of abnormal enhancement along the anterior chest wall,\npossibly within the ribs, which are also concerning for metastatic disease.",
+            "output": "1.  Re-demonstration of diffuse metastatic bone disease involving multiple\nthoracic vertebral bodies and posterior right ribs.  For comparison of extent\nis difficult, versus prior thoracic spine MRI given differences in planes of\nimaging.\n\n2.  Small of abnormal enhancement within the soft tissues of the right\nanterior and lateral chest wall, possibly within the ribs, which are\nconcerning for metastatic disease.\n\n3.  Right pleural thickening and enhancement with associated trace right\npleural effusion, also concerning for metastatic disease.\n\nRECOMMENDATION(S):  A bone scan is may be considered as clinically indicated\nfor further evaluation of the possible rib metastases if clinically suspicious\nfor progression since bone scan of ___."
+        },
+        {
+            "input": "LUNGS: Within limits of MRI, the lungs are clear.  Please refer to the\ndedicated CT chest from ___ for details.\n\nVASCULATURE: Patient is status post right chest wall infusion port placement\nwith tip at the cavoatrial junction, unchanged from prior exam.  Please note\nthat the evaluation for pulmonary embolism is limited on the current\ntechnique.  The ascending and descending aorta are not dilated.  The pulmonary\nartery appears well opacified centrally.\n\nHEART AND MEDIASTINUM: The heart is normal in size.  There is no pericardial\neffusion.  As previously, again seen is a soft tissue density in the anterior\nmediastinum measuring 1.9 x 4.0 cm.  There is evidence of dropout in signal on\nin and imaging, suggestive of intravoxel fat.  The ratio between in and out of\nphase images when compared to the paraspinal muscles measure 0.86 ___ et\nal.  AJNR ___ Jul;197(1):W15-20).  The enhancement is mostly homogeneous. \nThere is no lymphadenopathy in the mediastinum.\n\nUPPER ABDOMEN: The imaged portion of the upper abdomen is unremarkable.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: The imaged osseous structures and soft\ntissues are within normal limits.",
+            "output": "Soft tissue in the anterior mediastinum, most likely representing thymic\nhyperplasia given clinical history and signal characteristics.  No suspicious\nenhancement within the thymus.  No new lymphadenopathy."
+        },
+        {
+            "input": "LUNGS: Within limits of an MRI examination, no significant pulmonary\nabnormality seen.\n\nVASCULATURE: Again seen is a right sided Port-A-Cath with tip in the proximal\nright atrium.  The aorta is normal in caliber.  The main and central pulmonary\narteries are normally opacified.  Please note limitation of MRI for assessment\nof distal pulmonary arterial vessels.\n\nHEART AND MEDIASTINUM: Heart is normal in size.  There is no pericardial\neffusion.  Again seen is the mildly enhancing soft tissue density in the\nanterior superior mediastinum showing evidence of signal dropout on the out of\nphase images measuring approximately 3.5 x 2.0 cm (previously 4.0 x 1.9 cm). \nThe ratio between in and out of phase images compared to the paraspinal\nmuscles measures 0.5, which is in keeping with normal thymus/thymic\nhyperplasia ___ et al ___ AJNR).  No significantly enlarged mediastinal\nlymph nodes seen.\n\nUPPER ABDOMEN: No significant abnormality seen in the visualized upper\nabdomen.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: No abnormal marrow signal or soft tissue\nabnormality.",
+            "output": "Mild interval decrease in size of the thymic hyperplasia in the anterior\nmediastinum.  No suspicious mass or lymphadenopathy seen."
+        },
+        {
+            "input": "LUNGS: Postsurgical changes are again seen at the left lung base with a small\nleft pleural effusion.  Multiple nodules are seen along the left major fissure\nmeasuring up to 5 mm, unchanged and likely benign lymph nodes (8:26). \nMultiple enhancing T1 isointense and T2 hyperintense nodules are seen along\nthe posterior left pleura at the apex measuring 1.3 x 1.2 cm (10:11) and at\nthe left lung base measuring up to 1.5 x 0.7 cm, more conspicuous compared to\nprior exam (8:51, 52, 55).  A 3.4 x 2.6 cm T2 hyperintense enhancing mass is\nseen in the left costophrenic angle, previously measuring 3.9 x 2 cm, grossly\nsimilar to prior given difference in modality (11:11).\n\nVASCULATURE: No aortic aneurysm or significant atherosclerotic disease.\n\nHEART AND MEDIASTINUM: Heart size is normal.  No mediastinal lymphadenopathy\nor mass.\n\nUPPER ABDOMEN: The visualized portion of the upper abdomen is unremarkable.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: Postsurgical changes are seen along the\nleft chest wall.  Mild degenerative changes are seen in the thoracic spine. \nNo aggressive osseous lesion.  The thyroid gland is without concerning focal\nlesion.  A right chest Port-A-Cath is visualized terminating in the mid SVC.",
+            "output": "1. Multiple enhancing nodules along the left pleura, concerning for metastatic\ndisease.\n2. Left costophrenic angle mass is stable in size but avidly enhancing.  While\nthis may represent postsurgical sequela, metastatic disease can have a similar\nappearance.\n\nNOTIFICATION:   The impression and recommendation above was entered by Dr.\n___  ___ on ___ at 18:26 into the Department of Radiology\ncritical communications system for direct communication to the referring\nprovider."
+        },
+        {
+            "input": "There is marked, necrotic-appearing lymphadenopathy identified within the\nanterior mediastinum, prevascular area, left paratracheal, left suprahilar and\nright paratracheal stations.  The largest lymph nodes is seen in the left\nanterior lateral mediastinum and measures 2.4 cm.  The largest left\nparatracheal lymph node measures 1.6 cm.  The left largest suprahilar lymph\nnode measures 2.1 cm.  There is bilateral moderate-sized pleural effusions\nwhich are new compared to the prior study.  There is also significant increase\nin the consolidation in left upper lung lobe with bronchial wall thickening of\nthe upper lobe bronchi consistent with post obstructive bronchitis.\n\nPostcontrast administration there appears to be central hypervascularity of\nthe lymph nodes suggesting a more atypical source such as an a typical\ninfection, and based on the age of the patient less likely a neoplastic\nprocess.  Further characterization by means of biopsy is recommended.",
+            "output": "There is marked, necrotic-appearing lymphadenopathy identified within the\nanterior mediastinum, prevascular area, left paratracheal, left suprahilar and\nright paratracheal stations. Postcontrast administration there appears to be\ncentral hypervascularity of the lymph nodes suggesting a more atypical source\nsuch as an a typical infection, and based on the age of the patient less\nlikely a neoplastic process.\n\nRECOMMENDATION(S):  Further characterization by means of biopsy is\nrecommended."
+        },
+        {
+            "input": "AORTA: The patient is status post resection and grafting of the ascending and\nhemi-arch of the aorta for previous type A aortic dissection.\n\nAgain demonstrated is an anterior outpouching of the anterior aortic root,\nsuperior to the right coronary cusp (15b:61), and is unchanged since the most\nrecent prior study of ___.\n\nAgain identified is an aortic dissection extending from the distal thoracic\naorta at the level of the diaphragmatic hiatus (16b:53) into the proximal left\ncommon iliac artery (18b:72). The configuration and appearance of the\ndissection is unchanged since the most recent prior study. The celiac artery,\nSMA and right renal artery originate from the true lumen and are patent. \nThere is severe narrowing of the origin of the celiac axis with marked\npoststenotic aneurysmal dilation of the proximal celiac artery measuring up to\n16 mm in diameter (17b:5), which is unchanged from the prior study. The left\nrenal artery arises from both the true and false lumen, with the dissection\nflap extending into the left renal artery (17b:25). There is aneurysmal\ndilatation of the distal left renal artery which measures 15 x 13 mm and is\nunchanged since previous (17b:24). The inferior mesenteric artery arises from\nthe false lumen and fills retrograde.\n\nThe left common iliac artery is again dilated measuring 2.7 x 2.4 cm and is\nunchanged since previous (previously 2.6 x 2.5 cm).\n\nAortic measurements (all are unchanged since the most recent prior study):\n\nAortic root: 4.2 cm (10:6).\nAscending aorta: 2.7 cm (15b:40).\nAortic arch: 3.6 cm (15b:23).\nDescending aorta:  3.6 x 3.1 cm (15b:50).\nDescending aorta at the esophageal hiatus:  4.0 x 3.6 cm (16b:45).\nAbdominal aorta at the level of SMA:  4.0 x 3.4 cm (17b:14).\nInfrarenal abdominal aorta:  4.3 x 3.7 cm (17b:64).\n\nCHEST: There is evidence of prior sternotomy. No mediastinal, axillary or\nhilar lymphadenopathy is appreciated. There is minimal dependent atelectasis\nin the bilateral lung bases. No pericardial or pleural effusions are present.\n\nABDOMEN:  A few subcentimeter T2 hyperintense cystic lesions within the liver\n(6:34, 35, 37) are consistent with biliary hamartomas. The liver is otherwise\nunremarkable. The portal and hepatic veins are patent.  Incidental note is\nmade of a replaced right hepatic artery arising from the SMA. No intra or\nextrahepatic biliary duct dilatation is seen. There are multiple small\ngallstones within the gallbladder, which is nondistended and nonedematous.\n\nThere are multiple T2 hyperintense cystic lesions within both kidneys, the\nlargest of which measures 5.1 x 4.5 cm within the upper pole of the right\nkidney, consistent with a simple cyst.  A 6 mm T1 hyperintense lesion in the\nright upper pole renal cortex ___: 104) is compatible with a\nhemorrhagic/proteinaceous renal cyst. Both kidneys enhance symmetrically and\nexcrete contrast normally without hydronephrosis or suspicious renal mass. The\nbilateral adrenal glands and spleen are within normal limits. The pancreas\nshows normal signal intensity and homogeneous enhancement without pancreatic\nduct dilation.\n\nThere is a small axial hiatal hernia.  The stomach, duodenum and\nintra-abdominal loops of bowel are unremarkable except to note a few colonic\ndiverticula. There is a small fat-containing umbilical hernia. No\nlymphadenopathy or ascites is seen.\n\nPELVIS:  The urinary bladder and seminal vesicles are unremarkable.  The\nprostate is not well-visualized and is likely surgically absent. The rectum is\nwithin normal limits. No free pelvic fluid or pelvic lymphadenopathy is seen. \nUncomplicated bilateral small fat containing inguinal hernias are noted.\n\nThere is no bone marrow signal abnormality concerning for infection or\nmalignancy.",
+            "output": "1. Stable extent and appearance of distal thoracic and abdominal aortic\ndissection involving the left common iliac and left renal arteries. Aneurysmal\ndilatation of the abdominal aorta, left common iliac artery and distal left\nrenal artery are unchanged from the prior examination. Unchanged postsurgical\noutpouching of the anterior aortic root.\n\n2. Unchanged severe stenosis of the origin of the celiac artery with market\npost stenotic aneurysmal dilatation.\n\n3. Cholelithiasis without evidence of cholecystitis.\n\n4. Small axial hiatal hernia."
+        },
+        {
+            "input": "AORTA: The patient is status post resection and grafting of the ascending and\nhemi-arch of the aorta for previous type A aortic dissection.\n\nAgain demonstrated is an anterior outpouching of the anterior aortic root,\nsuperior to the right coronary cusp (15b:61), and is unchanged since the most\nrecent prior study of ___.\n\nAgain identified is an aortic dissection extending from the distal thoracic\naorta at the level of the diaphragmatic hiatus (16b:53) into the proximal left\ncommon iliac artery (18b:72). The configuration and appearance of the\ndissection is unchanged since the most recent prior study. The celiac artery,\nSMA and right renal artery originate from the true lumen and are patent. \nThere is severe narrowing of the origin of the celiac axis with marked\npoststenotic aneurysmal dilation of the proximal celiac artery measuring up to\n16 mm in diameter (17b:5), which is unchanged from the prior study. The left\nrenal artery arises from both the true and false lumen, with the dissection\nflap extending into the left renal artery (17b:25). There is aneurysmal\ndilatation of the distal left renal artery which measures 15 x 13 mm and is\nunchanged since previous (17b:24). The inferior mesenteric artery arises from\nthe false lumen and fills retrograde.\n\nThe left common iliac artery is again dilated measuring 2.7 x 2.4 cm and is\nunchanged since previous (previously 2.6 x 2.5 cm).\n\nAortic measurements (all are unchanged since the most recent prior study):\n\nAortic root: 4.2 cm (10:6).\nAscending aorta: 2.7 cm (15b:40).\nAortic arch: 3.6 cm (15b:23).\nDescending aorta:  3.6 x 3.1 cm (15b:50).\nDescending aorta at the esophageal hiatus:  4.0 x 3.6 cm (16b:45).\nAbdominal aorta at the level of SMA:  4.0 x 3.4 cm (17b:14).\nInfrarenal abdominal aorta:  4.3 x 3.7 cm (17b:64).\n\nCHEST: There is evidence of prior sternotomy. No mediastinal, axillary or\nhilar lymphadenopathy is appreciated. There is minimal dependent atelectasis\nin the bilateral lung bases. No pericardial or pleural effusions are present.\n\nABDOMEN:  A few subcentimeter T2 hyperintense cystic lesions within the liver\n(6:34, 35, 37) are consistent with biliary hamartomas. The liver is otherwise\nunremarkable. The portal and hepatic veins are patent.  Incidental note is\nmade of a replaced right hepatic artery arising from the SMA. No intra or\nextrahepatic biliary duct dilatation is seen. There are multiple small\ngallstones within the gallbladder, which is nondistended and nonedematous.\n\nThere are multiple T2 hyperintense cystic lesions within both kidneys, the\nlargest of which measures 5.1 x 4.5 cm within the upper pole of the right\nkidney, consistent with a simple cyst.  A 6 mm T1 hyperintense lesion in the\nright upper pole renal cortex ___: 104) is compatible with a\nhemorrhagic/proteinaceous renal cyst. Both kidneys enhance symmetrically and\nexcrete contrast normally without hydronephrosis or suspicious renal mass. The\nbilateral adrenal glands and spleen are within normal limits. The pancreas\nshows normal signal intensity and homogeneous enhancement without pancreatic\nduct dilation.\n\nThere is a small axial hiatal hernia.  The stomach, duodenum and\nintra-abdominal loops of bowel are unremarkable except to note a few colonic\ndiverticula. There is a small fat-containing umbilical hernia. No\nlymphadenopathy or ascites is seen.\n\nPELVIS:  The urinary bladder and seminal vesicles are unremarkable.  The\nprostate is not well-visualized and is likely surgically absent. The rectum is\nwithin normal limits. No free pelvic fluid or pelvic lymphadenopathy is seen. \nUncomplicated bilateral small fat containing inguinal hernias are noted.\n\nThere is no bone marrow signal abnormality concerning for infection or\nmalignancy.",
+            "output": "1. Stable extent and appearance of distal thoracic and abdominal aortic\ndissection involving the left common iliac and left renal arteries. Aneurysmal\ndilatation of the abdominal aorta, left common iliac artery and distal left\nrenal artery are unchanged from the prior examination. Unchanged postsurgical\noutpouching of the anterior aortic root.\n\n2. Unchanged severe stenosis of the origin of the celiac artery with market\npost stenotic aneurysmal dilatation.\n\n3. Cholelithiasis without evidence of cholecystitis.\n\n4. Small axial hiatal hernia."
+        },
+        {
+            "input": "MR ANGIOGRAM: Postsurgical changes related to prior repair ___ type A\ndissection are again noted, with persistent anterior outpouching of the aortic\nroot, unchanged in appearance (25:50).  The origins of the great vessels\narising from the aortic arch are patent.\n\nA ___ type B aortic dissection arises at the level of the diaphragmatic\nhiatus common extends into the left common iliac artery.  The overall\nconfiguration extent of the dissection appears similar compared to the prior\nexamination.  There is stable degree of concentric variability of the\nthrombosis in the false lumen.  There is persistent severe stenosis of the\nceliac artery, poststenotic dilatation measuring up to 14 mm (26:30),\nunchanged.  The celiac artery, superior mesenteric artery, and right renal\nartery arise from the true lumen.  The inferior mesenteric artery arises from\nthe false lumen and fills via retrograde flow.  Slight irregular thrombosis\nwithin the superior mesenteric artery near the origin is unchanged.  There is\nre- demonstration of a replaced right hepatic artery, arising from the\nsuperior mesenteric artery.\n\nThe aortic dissection flap extends into the left renal artery (2700, 22:74),\nwith predominant filling by the true lumen.  There is likely fenestration in\nthe proximal left renal artery. The false lumen of the left renal artery is\nopacified for only approximately 1.5 cm.  The distal left renal artery is\naneurysmal, spanning approximately 13 mm (27:79), unchanged.   Left common\niliac artery aneurysm is also noted (measured below).\n\nMeasurements include:\nAortic root:  3.9 x 4.4 cm\nAscending thoracic aorta at the level of the main pulmonary artery:  4.2 x 3.4\ncm\nProximal arch:  3.4 x 3.6 cm\nDistal arch:  3.6 x 3.6 cm\nMid descending:  3.8 x 3.8 cm\nDistal descending:  3.9 x 3.6 cm\nSuprarenal abdominal aorta:  4.1 x 3.7 cm\nInfrarenal abdominal aorta:  4.1 x 3.6\nLeft common iliac artery:  2.8 x 2.2 cm\n\n\nLUNGS:  A 6mm pulmonary nodule in the right middle lobe is stable since the\nchest CT from ___ (25:13).  There is no pleural effusion.\n\nHEART AND MEDIASTINUM: The heart and mediastinum are unremarkable.  There is\nno mediastinal or hilar lymphadenopathy.  No pericardial effusion is\nidentified.\n\nABDOMEN:  There is a small hiatal hernia.  The liver is unremarkable with\nexception of small cysts or biliary hamartomas, unchanged (5:5).  The\npancreas, spleen, and bilateral adrenal glands are normal in appearance. \nThere are several simple cysts in the bilateral kidneys, unchanged.  The\ngastrointestinal tract is within normal limits.  There is no free fluid in the\nabdomen.  No retroperitoneal or mesenteric lymphadenopathy is present.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: No osseous lesion worrisome for\nmalignancy or infection is identified.",
+            "output": "1. Overall stable appearance of Type B aortic dissection.\n2. Graft repair of prior Type A dissection is unchanged.\n3. Aneurysmal dilation of the left common iliac artery, distal left renal\nartery, and celiac artery just beyond celiac origin stenosis are overall\nunchanged.\n4. Hepatic and renal cysts."
+        },
+        {
+            "input": "There are bilateral pleural effusions, left greater than right\nside.  There is a large anterior and middle mediastinal mass which extends\nanterior to the branch vessels of the aorta.  It extends inferiorly anterior\nto the arch and posterior to the sternum and involves the sternum.  It extends\nfurther inferiorly to surround the main pulmonary artery and the proximal\npericardium.  It encases the left brachiocephalic vein.  It encases the\ninternal mammary arteries.  The mass extends down to the aortopulmonary window\nand the subcarinal space.  The mass encases the branch vessels of the aorta\nextending posteriorly between the SVC and trachea and abutting the azygos\nvein.  Anteriorly, it elevates the left pectoralis muscle.\n\nNo evidence of any occlusion of any of the vasculature.  No evidence of any\nemboli.\n\n2D and 3D reformations provided multiple perspectives for the dynamic series.",
+            "output": "1.  Large anterior and middle mediastinal mass which surrounds and abuts the\naorta and pulmonary artery as well as the branch vessels of the aorta,\ninvolves the sternum and elevates and slightly invadses the left pectoralis\nanteriorly and inferiorly involves the pericardium.  The appearance is most\nlikely that of an aggressive thymoma.\n\n2.  Bilateral pleural effusions with associated atelectasis, left more than\nright side."
+        },
+        {
+            "input": "Motion artifact degrades the quality of the study.\n\nIn the anterior mediastinum prevascular space extending inferiorly anterior to\nthe heart, there is lobulated soft tissue lesion in a triangular configuration\nwhich is mildly hyperintense on the T2 weighted images.   There is signal loss\non the out of phase sequence as opposed to the in phase sequence consistent\nwith intravoxel fat.  This area measures approximately 2.0 x 4.6 cm and is\nunchanged compared to the prior exam. This area is most consistent with thymic\nhyperplasia.  There are no discrete masses.\n\nThere are bilateral simple appearing 4 and 2 mm cysts in the right and left\nlobes of the thyroid respectively.\n\nNo supraclavicular or axillary lymphadenopathy by size criteria.\n\nThe great vessels are of normal caliber throughout.  Heart size is normal.  No\npericardial effusion.\n\nAlthough the study is not optimized for assessment of the lung parenchyma.  No\ngross masses.  No areas of consolidation.  No mediastinal or hilar\nlymphadenopathy by size criteria.\n\nThe visualized portion of the abdomen is not well assessed due to motion\nartifact.\n\nThe bone marrow demonstrates normal signal characteristics.  No concerning\nosseous lesions.",
+            "output": "Soft tissue in the anterior mediastinum appears unchanged from CT chest ___ and is compatible with thymic hyperplasia."
+        },
+        {
+            "input": "The study is mildly limited by motion.\n\nLUNGS: The study is not targeted for evaluation of lung parenchyma.  Within\nthis limitation, there is no focal consolidation or mass.  No pleural\neffusion.\n\nVASCULATURE: The thoracic aorta appears normal in caliber.\n\nHEART AND MEDIASTINUM: Visualized thyroid appears unremarkable.  Visualized\nportion of the base of the neck appears unremarkable.  There is no axillary\nlymphadenopathy or supraclavicular lymphadenopathy.  In the anterior\nmediastinum, there is significant decrease in soft tissue with again loss of\nsignal on out of phase imaging suggesting intravoxel fat now measuring\napproximately 3.7 x 1.8 cm, previously measuring at least 7.3 x 2.0 cm (4; 21)\nconsistent with thymic hyperplasia.  There is no mediastinal lymphadenopathy. \nThe heart is not enlarged.  There is no pericardial effusion.\n\nUPPER ABDOMEN: Visualized portion of the upper abdomen appears unremarkable.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: No suspicious osseous lesion is\nidentified.",
+            "output": "Interval decrease in anterior mediastinal soft tissue which again drops in\nsignal on out of phase imaging consistent with thymic hyperplasia, decreased\ncompared to prior."
+        },
+        {
+            "input": "Within the skin and subcutaneous tissues of the anterior right chest wall\nthere is a STIR hyperintense and T1 hypo intense lesion, which measures\napproximately 1.7 x 4.4 x 5.3 cm (AP, transverse, cc dimension).  There are\nmultiple hypo intense curvilinear flow voids within the lesion and within the\nsurrounding subcutaneous fat.  There is a large tortuous artery that leads\nfrom the right internal mammary artery to the lesion, better delineated on\nprior CT.  No definite nidus identified, however, this study was not tailored\nto evaluate the vasculature.  The associated T1 hypointense and STIR\nhypointense signal is non mass like, suggesting this may represent a vascular\nmalformation.  Difficult to definitively exclude a highly vascularized soft\ntissue tumor.  There is thickening of the overlying skin.  In addition, there\nis a smaller ill defined nodular T1 hypointense and STIR hyperintense area\ndeep the dominant lesion measuring up 1.3 x 0.8 x 1.5 cm (series 6, image 15).\nThere are flow voids leading to and within this area as well.  This second\nportion of the lesion abuts the fascia overlying the pectoralis muscle.  No\nevidence of definite involvement of the pectoralis muscle.  Postcontrast\nimaging demonstrates enhancement within both lesions.\n\nNo axillary lymphadenopathy.\n\nNo suspicious bone marrow signal.",
+            "output": "T1 and STIR hypointense lesion in the right anterior chest wall subcutaneous\ntissues involving the overlying skin with multiple large flow voids.  The\nabnormal signal intensity is non mass like in configuration and likely\nrepresents a vascular malformation, however, a highly vascular tumor cannot be\nexcluded.\n\nNOTIFICATION:  The findings were discussed with Dr.  ___, M.D. by\n___, M.D. on the telephone on ___ at 8:22AM, 5 minutes\nafter discovery of the findings."
+        },
+        {
+            "input": "In the anterior mediastinum, there is soft tissue measuring 19 x 11 mm which\nis triangular in configuration and demonstrates signal loss on the out of\nphase sequence as opposed to the in phase sequence consistent with intravoxel\nfat.  This constellation of finding is most in keeping with thymic\nhyperplasia.  There are no masses.\n\nNo mediastinal or hilar lymphadenopathy by size criteria.\n\nThere is conventional 3 arch anatomy.  The great vessels are normal in\ncaliber.  Heart size is normal.  No pericardial effusion.\n\nThe lungs are clear.  No pleural effusion.\n\nThe thyroid gland is within normal limits.\n\n The bone marrow demonstrates normal signal characteristics.  No concerning\nosseous lesions.",
+            "output": "1.  Thymic hyperplasia\n2.  No thymic masses."
+        },
+        {
+            "input": "MRA:  The superior vena cava, bilateral subclavian veins and axillary veins\nare patent and contrast opacified.  Superficial venous branches of the\ndraining from the anterior aspect of the right upper arm are also contrast\nopacified, although course immediately adjacent to the soft tissue mass\ndescribed below.\n\nMRI: There is extensive soft tissue abnormality centered anterior to the right\nshoulder joint.  This material spans 6.7 cm caudocranially, 8.4 cm\ntransversely and 3.1 cm anterior to posterior. This is soft tissue is slightly\nhyperintense has to skeletal muscle on T2 weighted imaging, isointense to\nskeletal muscle on T1 weighted imaging and is avidly and progressively\nenhancing. The margins are irregular and infiltrative, involving multiple\nmyofascial planes.  There is infiltration of the medial aspect of the right \ndeltoid, lateral aspect of the pectoralis, and anterior biceps muscles.  The\nnoninvolved muscle maintains normal signal without identified edema or\ninflammation. Along the medial aspect there is deeper infiltration to the\nthoracic chest wall, with abnormal enhancement involving the intercostal\nmuscles surrounding the first rib (17:55). There is no extension into the\nthoracic cavity. No pleural effusion or airspace opacity is seen.\n\nInnumerable osseous metastases are seen throughout the visualized spine,\ncorrelating with appearance on the prior CT.\n\nLimited evaluation of the upper abdomen is notable for a T2 hyperintense,\nnonenhancing cysts scattered throughout the liver and bilateral kidneys.\n\nNote is made of bilateral mastectomies and reconstructions.\n\nThe arms beyond the shoulders are not included in the field of view and are\nnot assessed for edema.",
+            "output": "Extensive abnormal enhancing soft tissue process infiltrating anterior right\nchest wall and proximal arm musculature and extending towards but not into the\nright thoracic cavity.  While this could represent recurrence of known\nmetastatic breast cancer, the infiltrative appearance and progressive\nenhancement is atypical, and can also be seen with other tumors such as\nlymphoma or desmoid tumor.  Lack of surrounding edema argues against an\ninflammatory myositis and contours are not typical for radiation myositis. The\ndeep venous structures of the thorax remain patent at this time.\n\nNOTIFICATION:  Findings were discussed with person between Dr ___ Dr\n___ at approximately 16:30 on ___."
+        },
+        {
+            "input": "Study is severely degraded by motion despite repeating sequences.\n\nThere is no definite lesion visualized at the right eleventh costochondral\njunction corresponding to the increased SUV uptake in the previous PET-CT. \nNoting that there is motion artifact.\n\nThe evaluation of the intra-abdominal structures are significantly limited due\nto severe motion artifact.  There are multiple high T2 lesions in the liver\nwith no internal enhancement poorly characterized at the current study likely\nrepresenting previously described cysts and better assessed on the dedicated\nprior liver MRI studies..\n\nThere are also bilateral renal high T2 lesions obscured by the significant\nmotion artifact with grossly no internal enhancement likely representing the\npreviously described cysts.  There are severe degenerative changes and\nscoliosis throughout the thoracolumbar spine.\n\nThere bilateral trace pleural effusion.  There is small ascites visualized.",
+            "output": "No definite lesion visualized at the right eleventh costochondral junction\ncorresponding to the increased SUV uptake in the previous PET-CT.  Noting that\nsignificantly limited evaluation due to severe motion artifact."
+        },
+        {
+            "input": "LUNGS: There is a 3.7 x 2.4 x 3.0 cm oval, predominantly T2 hyperintense, T1\nhypointense, well-circumscribed lesion with peripheral enhancement including\nfocal enhancing nodularity located along the posterior-lateral left upper lung\npleura (series 3, image 24; series 4, image 30; series 11, image 27).  The\ndominant nodular component measures 1.0 x 0.6 cm, located along the\nposterolateral aspect of the lesion (series 11, image 28).  There is no\nmicroscopic or macroscopic fat within this lesion.  There appears to be a\ncurvilinear line of subpleural fat between the margins of the lesion and the\nadjacent lung. The lesion does not appear to extend beyond the lateral margins\nof the intercostal structures.  The remainder of the imaged lungs is\nunremarkable.  No pleural effusion.\n\nVASCULATURE: The thoracic aorta is normal in caliber.  No evidence of\ndissection.  Incidental common origin of the left common carotid and\ninnominate arteries.  The main pulmonary artery is normal in caliber.  No\ncentral pulmonary embolism.\n\nHEART AND MEDIASTINUM: No cardiomegaly.  No upper mediastinal lymphadenopathy.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: No suspicious osseous lesions.  The\nabdominal wall is unremarkable.",
+            "output": "A cystic lesion with peripheral enhancing nodularity located along the\nposterolateral left upper lung pleura is probably a cystic neurogenic tumor\nrelated to the intercostal nerve or a branch of the intercostal nerve.  Less\nlikely considerations include a solitary fibrous tumor of the pleura given the\nrelatively small amount of solid tissue and probable extra pleural location,\nor cystic/necrotic malignancy such as mesothelioma or primary lung cancer\ngiven probable extra pleural location."
+        },
+        {
+            "input": "MRI OF THE CHEST WITH AND WITHOUT IV CONTRAST:\n\nA 3.1 x 2.5 cm retrosternal goiter arising from the lower pole of the right\nthyroid lobe is again seen (series 4, image 7), unchanged in size since the CT\nexamination from ___, demonstrating intermediate signal intensity on\nT2 weighted sequences with moderate contrast enhancement (series 15, image\n40). At least three left supraclavicular lesions demonstrate high signal\nintensity on T2 weighted sequences, with avid contrast enhancement, the\nlargest measuring 3.2 x 2.3 cm (series 9, image 9). T1 and T2 signal\ncharacters are slightly different from the thryoid, making it less likely to\nbe ectopic thyroid tissue, and are most likely enlarged lymph nodes. Only the\ntwo lower nodes are visualized on the CT examination from ___,\nappearing similar in size.\n\nA paraesophageal nodule measuring 16 x 9 mm appears stable (series 9, image\n12). There is no hilar lymphadenopathy. No pulmonary mass or nodule is\ndetected.\n\nProminent triangular-shaped anterior mediastinal tissue demonstrates moderate\nsignal drop-off on T1 weighted out of phase images in comparison to in phase\nsequences (series 11 image 43), compatible with hyperplastic thymic tissue.\n\nThe left common carotid and innominate arteries arise from a common trunk\n(series 15, image 49). The thoracic aorta and pulmonary arteries are patent\nand normal in caliber. The subclavian and carotid arteries are patent and\nnormal in caliber. No pulmonary embolus is detected at the proximal\nsubsegmental levels.\n\nThe heart size is normal. There is no pericardial effusion.\n\nThere is mild bibasilar dependent atelectasis (series 1403, image 106). There\nis no pleural effusion.\n\nIncluded views of the liver, spleen, kidneys, spleen, adrenal glands, stomach,\nand splenic flexure are within normal limits.\n\nThere are no bony lesions concerning for malignancy or infection.",
+            "output": "1. Multiple abnormally-enlarged left supraclavicular lymph nodes, measuring up\nto 3.2 cm. Ultrasound-guided biopsy/FNA recommended, assuming the cause is not\nalready known.\n2. Very large right-sided low cervical/retrosternal goiter.  Based on it size,\nadvise biopsy/FNA which can also be performed at the time of lymph node FNA.\n3. Enlarged paraesophageal lymph node remains stable since ___\nexamination.\n4. Hyperplastic thymic tissue."
+        },
+        {
+            "input": "Motion artifact from breathing, inhomogeneous fat saturation and the lack of\nintravenous contrast limits interpretation of the study.\n\nLUNGS: There are moderate-sized bilateral pleural effusions, increased in size\nfrom the prior study.  No large lung mass is identified.\n\nVASCULATURE: Limited evaluation but no obvious abnormality.\n\nHEART AND MEDIASTINUM: Limited evaluation but no obvious abnormality.\n\nOSSEOUS STRUCTURES AND SOFT TISSUES: No definite abnormal signal or edema is\nseen in the region of the left sternoclavicular joint or manubrium.  No fluid\nseen in the sternoclavicular joints.  However, as noted above, there is marked\nmotion artifact.",
+            "output": "Technically limited study as outlined above.  Allowing for the limitations of\nthis study, there is no evidence of edema in the left sternoclavicular joint. \nPlease note that prior chest CT demonstrates normal appearing sternoclavicular\njoint and  manubrium without evidence of effusion."
+        },
+        {
+            "input": "Patient is intubated.  Orogastric tube passes into the stomach.\n\nThe great arch vessels and the thoracic aorta appears normal in contour and\ncaliber.  Arteries of the chest are widely patent without stenoses.  There is\nno wall thickening, hyperenhancement or edema in the wall of the aorta or the\nproximal great arch vessels of the chest.\n\nThe heart is normal in size.  There are trace bilateral pleural effusions. \nThere is no significant pericardial effusion.",
+            "output": "No evidence for vasculitis in the chest."
+        },
+        {
+            "input": "Within the anterior costophrenic angle of the right hemithorax is a triangular\ncystic structure. This is T2 hyperintense, T1 hypointense and nonenhancing. It\nhas smooth, rounded contour with subtle, thin septations anteriorly. This has\n___ of 6 cm anterior to posterior, 3 cm caudocranially and 11 cm\ntransversely. This conforms to its space, respecting the anterior margin of\nthe major fissure. It abuts the free wall of the right atrium and right\nventricle, without mass effect on the heart. This structure is unchanged in\nshape, size and signal/enhancement characteristics, and is consistent with a\nbenign pericardial cyst.\n\nNo additional mediastinal mass is identified. Cardiac function is not assessed\non this examination. The morphology of the heart is normal. There is\nconventional vascular anatomy of the chest.\n\nThere is mild consolidative change within the dependent portions of each lung,\npresumably from hypo ventilation.\n\nLimited evaluation the upper abdomen reveals no additional incidental\nabnormality.  There is no evidence of hepatic steatosis.",
+            "output": "Unchanged benign pericardial cyst within the anterior costophrenic angle of\nthe right hemithorax."
+        },
+        {
+            "input": "At the level of the pulmonary artery, the ascending aorta measures\n3.5 cm in maximum dimension and the descending aorta measures 3 cm in maximum\ndimension.  In the anterior mediastinum in the prevascular area, note is made\nof a lesion of high signal intensity on both FIESTA and T2-weighted imaging,\nwhich measures 13 mm and may represent a thymic cyst.  This was also seen on\nthe previous CT from ___ and ___ and is unchanged.  At the level of\nthe diaphragmatic hiatus, the suprarenal aorta measures 2.5 cm.\n\nNo evidence of any dissection.  No evidence of any pulmonary embolus.\n\nThe lungs where visualized are normal.  The origins of the brachiocephalic,\nleft carotid, and left subclavian arteries are normal.\n\nThe lungs where visualized are normal.\n\nNote is made of a gastric pull-up in the right side of the chest in this\npatient status post esophagectomy.\n\nUpper cuts of the abdomen reveal a cyst in the upper pole of the right kidney\nmeasuring 17 mm.  Visualized images of the liver and spleen appear\nunremarkable.\n\nThe osseous structures where visualized are normal.\n\n2D and 3D reformations provided multiple perspectives for the dynamic series.",
+            "output": "1.  No evidence of any aortic dissection.\n2.  Gastric pull-up in patient status post esophagectomy.\n3.  Incidental right renal cyst noted."
+        },
+        {
+            "input": "Four markers denote the area of clinical concern.\n\nImmediately deep to the right upper trapezius muscle, there is a\nwell-circumscribed 5.1 cm CC by 1.3 cm AP by 5.4 cm transverse T1 hyperintense\nlesion which demonstrates loss of signal on fat saturated sequences.  There is\na single enhancing septation--although this appears thin, it measures up to 2\nmm in thickness.  No evidence of nodular soft tissue component.  No other\nseptations identified.  Otherwise, no convincing internal enhancement.\n\nThe mass lies deep to the right trapezius muscle, overlying the rhomboid\nmuscles.  Surrounding muscles and overlying subcutaneous fat are within normal\nlimits.\n\nNo other focal mass fluid collection is detected in this area.  No overlying\nsoft tissue edema.\n\nVisualized muscles and bones about the upper chest are otherwise grossly\nunremarkable.\n\nThis examination is not diagnostic for evaluation of the lung parenchyma. \nHowever, bibasilar dependent atelectasis is noted.",
+            "output": "Palpable abnormality corresponds to a 5.1 x 1.3 x 5.4 cm fat containing lesion\ndeep to the right upper trapezius muscle, likely representing a lipoma. Note\nis made of a single internal septation that is at the upper limits of normal\nin thickness.  No evidence of nodular soft tissue thickening or focus of\nnodular enhancement to suggest malignancy.\n\nRecommend follow-up MRI in ___ year to confirm expected stability.  Also\nrecommend re-imaging if there is a change in symptoms or interval growth\nrelated to this lesion.\n\nRECOMMENDATION(S):  Recommend follow-up MRI in ___ year to confirm expected\nstability.\n\nAlso recommend re-imaging if there is a change in symptoms or interval growth\nrelated to this lesion."
+        },
+        {
+            "input": "A external marker overlies the right upper posterior chest wall, in the area\nof patient's palpable abnormality.  Compared with ___, a\nwell-circumscribed 5.4 x 1.4 (TRV x AP) fat density lesion immediately deep to\nthe right trapezius muscle is not significantly changed in size, previously\nmeasuring 5.4 x 1.3 cm.  Although the mass appears slightly longer in the CC\ndirection, spanning approximately 5.7 cm compared with 5.1 cm previously, the\npatient is slightly oblique, likely accounting for this difference.  This mass\nagain contains a single septation measuring up to 2 mm in thickness.  No new\nthick septal or nodular enhancement.\n\nThe bone marrow intensity appears isointense to muscle on T1 weighted imaging,\nslightly lower in signal than normally seen, however unchanged and may be\nrelated to red marrow conversion.  There is a 5 mm T1 hyperintense enhancing\nlesion in a midthoracic vertebral body, only included on the axial images,\nsaturates out on fat sat precontrast images and is not well seen on STIR\nweighted imaging (09:33; 03:33).",
+            "output": "1. A fat density lesion in the right posterior chest wall with a single thin\ninternal enhancing septation is not significantly changed compared with\n___, with slight increase in the length of the mass in the CC\ndirection accounted for by differences in obliquity of the patient, favored a\nlipoma.  No new thick septal or nodular enhancement.\n2. The signal intensity of the bone marrow on T1 weighted imaging is\nrelatively hypointense, however is unchanged and may be related to red marrow\nconversion. Correlate clinically.\n3. A 5 mm enhancing lesion in a midthoracic vertebral body is favored a\nhemangioma, however given the history of pheochromocytoma, metastasis\ndifficult to exclude.  MIBG nuclear medicine imaging could be performed if\nthere is clinical concern for metastases."
+        }
+    ]
+}