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positive regulation of MHC class II biosynthetic process positive regulation of transcription by RNA polymerase II Ras protein signal transduction regulation of transcription by RNA polymerase II |
negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation protein dephosphorylation |
G protein-coupled receptor signaling pathway phototransduction |
actin cytoskeleton organization actin filament organization cellular response to type II interferon positive regulation of actin filament polymerization positive regulation of protein-containing complex assembly positive regulation of pseudopodium assembly regulation of cell shape Rho protein signal transduction |
cellular response to oxidative stress protein maturation by copper ion transfer removal of superoxide radicals superoxide metabolic process |
adenylate cyclase-activating G protein-coupled receptor signaling pathway antimicrobial humoral immune response mediated by antimicrobial peptide cell-cell signaling cellular response to lipopolysaccharide chemokine-mediated signaling pathway chemotaxis inflammatory response neutrophil chemotaxis positive regulation of release of sequestered calcium ion into cytosol regulation of cell population proliferation signal transduction T cell chemotaxis |
animal organ morphogenesis anterior/posterior axis specification blood vessel development cell differentiation labyrinthine layer development negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
regulation of DNA-templated transcription |
ATP metabolic process basophil activation involved in immune response negative regulation of inflammatory response negative regulation of mast cell activation involved in immune response negative regulation of mast cell proliferation nucleoside triphosphate catabolic process phosphate ion homeostasis phosphate-containing compound metabolic process pyrimidine nucleotide metabolic process |
animal organ morphogenesis cilium assembly cytoskeleton organization lamellipodium assembly visual perception |
canonical Wnt signaling pathway cochlea morphogenesis convergent extension involved in neural plate elongation heart development heart looping intracellular signal transduction neural tube closure non-canonical Wnt signaling pathway outflow tract morphogenesis planar cell polarity pathway involved in neural tube closure positive regulation of DNA-binding transcription factor activity positive regulation of JNK cascade positive regulation of JUN kinase activity positive regulation of neuron projection arborization positive regulation of protein phosphorylation positive regulation of transcription by RNA polymerase II protein localization regulation of actin cytoskeleton organization regulation of cell population proliferation regulation of DNA-templated transcription segment specification Wnt signaling pathway, planar cell polarity pathway |
sperm flagellum assembly |
cellular response to hypoxia cellular response to zinc ion chemical synaptic transmission cochlea development monoatomic ion transmembrane transport negative regulation of cytosolic calcium ion concentration potassium ion transmembrane transport potassium ion transport regulation of resting membrane potential response to xenobiotic stimulus stabilization of membrane potential |
intra-Golgi vesicle-mediated transport protein transport vesicle fusion |
cell adhesion chaperone cofactor-dependent protein refolding chaperone-mediated protein folding ER-associated misfolded protein catabolic process intermediate filament cytoskeleton organization neuron projection development nuclear envelope organization nuclear membrane organization organelle organization positive regulation of synaptic vesicle endocytosis protein deneddylation protein localization to nucleus regulation of dopamine uptake involved in synaptic transmission regulation of protein localization to cell surface response to oxidative stress synaptic vesicle membrane organization synaptic vesicle transport wound healing, spreading of cells |
chaperone cofactor-dependent protein refolding endoplasmic reticulum organization nuclear membrane organization protein localization to nucleus response to unfolded protein |
endocytic recycling intracellular protein transport retrograde transport, endosome to Golgi vesicle docking vesicle fusion |
cellular response to leukemia inhibitory factor cobalamin metabolic process cobalamin transport fatty acid beta-oxidation long-chain fatty acid import into peroxisome peroxisome organization transmembrane transport very long-chain fatty acid catabolic process |
apoptotic process macroautophagy negative regulation of cell growth |
negative regulation of translation nervous system development positive regulation of neuron projection development proteasomal ubiquitin-independent protein catabolic process protein ubiquitination |
cell population proliferation negative regulation of cell population proliferation positive regulation of prostaglandin secretion prostaglandin biosynthetic process prostaglandin metabolic process regulation of fever generation regulation of inflammatory response sensory perception of pain signal transduction |
response to amphetamine tRNA methylation tRNA modification tRNA stabilization |
cellular response to dsDNA cellular response to dsRNA cellular response to virus chromosome segregation defense response to virus innate immune response maturation of SSU-rRNA negative regulation of canonical NF-kappaB signal transduction negative regulation of MDA-5 signaling pathway negative regulation of protein-containing complex assembly phosphorylation positive regulation of innate immune response positive regulation of interferon-beta production |
inositol biosynthetic process inositol metabolic process phosphate-containing compound metabolic process phosphatidylinositol phosphate biosynthetic process response to lithium ion signal transduction |
apoptotic process cellular response to interleukin-1 cellular response to lipopolysaccharide cellular senescence Fc-epsilon receptor signaling pathway JNK cascade phosphorylation positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of JNK cascade positive regulation of JUN kinase activity positive regulation of telomerase activity positive regulation of telomere capping positive regulation of telomere maintenance via telomerase regulation of motor neuron apoptotic process response to heat response to osmotic stress response to tumor necrosis factor response to UV response to wounding signal transduction stress-activated MAPK cascade |
acyl-CoA metabolic process alpha-linolenic acid metabolic process bile acid biosynthetic process dicarboxylic acid catabolic process fatty acid beta-oxidation using acyl-CoA oxidase fatty acid catabolic process negative regulation of CD4 production peroxisome fission |
phosphatidylinositol biosynthetic process |
apoptotic process cellular response to transforming growth factor beta stimulus negative regulation of cell population proliferation negative regulation of chaperone-mediated protein folding positive regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of gene expression positive regulation of protein insertion into mitochondrial outer membrane positive regulation of release of cytochrome c from mitochondria |
chromatin remodeling circadian regulation of gene expression DNA-templated transcription termination endothelial cell activation Golgi ribbon formation liver regeneration negative regulation of cell differentiation peptidyl-arginine methylation peptidyl-arginine N-methylation positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway positive regulation of mRNA splicing, via spliceosome positive regulation of oligodendrocyte differentiation regulation of DNA methylation regulation of DNA-templated transcription regulation of ERK1 and ERK2 cascade regulation of mitotic nuclear division regulation of signal transduction by p53 class mediator spliceosomal snRNP assembly |
androgen biosynthetic process androgen catabolic process brexanolone catabolic process retinol metabolic process steroid metabolic process |
activation of NF-kappaB-inducing kinase activity apoptotic process cell surface receptor signaling pathway cellular response to mechanical stimulus defense response to tumor cell extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction regulation of apoptotic process response to endoplasmic reticulum stress TRAIL-activated apoptotic signaling pathway |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway signal transduction synaptic transmission, GABAergic |
animal organ morphogenesis brain development embryonic pattern specification eye development negative regulation of myeloid cell differentiation negative regulation of transcription by RNA polymerase II pancreas development positive regulation of cardiac muscle myoblast proliferation positive regulation of cell population proliferation positive regulation of mitotic cell cycle positive regulation of transcription by RNA polymerase II response to growth factor response to mechanical stimulus visual learning |
regulation of transcription by RNA polymerase II |
fucose metabolic process |
bone resorption central nervous system development epithelial cell differentiation lipid metabolic process lysosomal protein catabolic process lysosome organization nervous system development neuromuscular process controlling balance peptide catabolic process protein catabolic process protein localization to chromosome, telomeric region proteolysis |
dark adaptation dopamine receptor signaling pathway G protein-coupled receptor signaling pathway light adaption negative regulation of voltage-gated calcium channel activity positive regulation of GTPase activity signal transduction |
attachment of mitotic spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore cell division centrosome duplication chromosome segregation establishment of mitotic spindle orientation G2/MI transition of meiotic cell cycle kinetochore organization metaphase chromosome alignment mitotic cell cycle mitotic sister chromatid segregation mitotic spindle assembly checkpoint signaling mitotic spindle organization positive regulation of mitotic cell cycle spindle assembly checkpoint regulation of protein stability skeletal muscle satellite cell proliferation spindle assembly involved in female meiosis I |
microtubule-based movement |
protein import into nucleus |
chloride transmembrane transport cholesterol metabolic process cytolysis by host of symbiont cells innate immune response lipid transport lipoprotein metabolic process |
glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
adaptive immune response innate immune response leukocyte activation involved in immune response positive regulation of innate immune response positive regulation of natural killer cell mediated immunity |
positive regulation of apoptotic process TRAIL-activated apoptotic signaling pathway |
G protein-coupled receptor signaling pathway sensory perception of chemical stimulus signal transduction |
actin cytoskeleton organization cellular response to leukemia inhibitory factor Ras protein signal transduction |
chemical synaptic transmission exocytosis insulin secretion regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane regulation of exocytosis regulation of neurotransmitter secretion regulation of synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle exocytosis |
dopaminergic neuron differentiation locus ceruleus development midbrain development noradrenergic neuron differentiation oculomotor nerve formation positive regulation of transcription by RNA polymerase II regulation of respiratory gaseous exchange regulation of transcription by RNA polymerase II somatic motor neuron differentiation sympathetic nervous system development trochlear nerve formation |
digestion proteolysis |
protein-containing complex assembly |
proteasomal protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process |
post-Golgi vesicle-mediated transport protein transport |
detection of stimulus involved in sensory perception protein dephosphorylation |
detection of stimulus involved in sensory perception negative regulation of MAPK cascade negative regulation of peptidyl-threonine phosphorylation protein dephosphorylation regulation of JUN kinase activity regulation of MAP kinase activity visual perception |
2-oxobutyrate catabolic process 2-oxoglutarate metabolic process fatty acid alpha-oxidation isoprenoid metabolic process methyl-branched fatty acid metabolic process |
adaptive immune response B cell homeostasis cell surface receptor signaling pathway hematopoietic progenitor cell differentiation negative regulation of B cell proliferation |
G protein-coupled receptor signaling pathway glucose homeostasis insulin secretion ion channel modulating, G protein-coupled receptor signaling pathway ligand-gated ion channel signaling pathway negative regulation of interleukin-1 beta production phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of calcium ion transport positive regulation of cytosolic calcium ion concentration positive regulation of insulin secretion response to fatty acid |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to fatty acid G protein-coupled receptor signaling pathway inflammatory response mucosal immune response negative regulation of blood pressure positive regulation of acute inflammatory response to non-antigenic stimulus positive regulation of chemokine production positive regulation of cytokine production involved in immune response regulation of hormone biosynthetic process regulation of insulin receptor signaling pathway regulation of norepinephrine secretion regulation of peptide hormone secretion |
activation of innate immune response AIM2 inflammasome complex assembly brain development cellular response to interferon-beta cellular response to xenobiotic stimulus defense response to virus DNA damage response immune response inflammatory response innate immune response negative regulation of NF-kappaB transcription factor activity negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction neuron cellular homeostasis pattern recognition receptor signaling pathway positive regulation of cysteine-type endopeptidase activity positive regulation of defense response to virus by host positive regulation of inflammatory response positive regulation of interleukin-1 beta production positive regulation of NF-kappaB transcription factor activity pyroptosis pyroptosome complex assembly regulation of behavior T cell homeostasis tumor necrosis factor-mediated signaling pathway |
response to toxic substance response to zinc ion zinc export across plasma membrane zinc ion import into lysosome zinc ion transmembrane transport |
DNA repair negative regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of metabolic process regulation of transcription by RNA polymerase II |
amino acid catabolic process branched-chain amino acid catabolic process lipid biosynthetic process negative regulation of cellular amino acid metabolic process phosphorylation regulation of glucose metabolic process |
antiviral innate immune response defense response to virus negative regulation of apoptotic process negative regulation of cell population proliferation response to virus |
arachidonic acid metabolic process leukotriene biosynthetic process lipid metabolic process prostanoid metabolic process |
cell cycle regulation of G1/S transition of mitotic cell cycle |
cell development cranial skeletal system development immune system process keratinocyte differentiation keratinocyte proliferation limb development mammary gland epithelial cell differentiation negative regulation of cell population proliferation negative regulation of keratinocyte proliferation negative regulation of stem cell proliferation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II roof of mouth development stem cell proliferation |
apoptotic process cellular response to peptide negative regulation of cell population proliferation negative regulation of transcription by RNA polymerase II positive regulation of apoptotic process regulation of G1/S transition of mitotic cell cycle regulation of transcription by RNA polymerase II |
canonical Wnt signaling pathway cell fate commitment cellular response to retinoic acid cornea development in camera-type eye embryonic skeletal joint development iris morphogenesis negative regulation of cell population proliferation negative regulation of chondrocyte differentiation neuron differentiation |
activation of GTPase activity negative regulation of cell population proliferation negative regulation of protein localization to cell surface negative regulation of Wnt signaling pathway Rho protein signal transduction Wnt signaling pathway |
cellular response to interleukin-7 chemical synaptic transmission endothelial cell migration G protein-coupled receptor signaling pathway glutamate secretion negative regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of cytokinesis positive regulation of melanin biosynthetic process positive regulation of transforming growth factor beta receptor signaling pathway presynaptic modulation of chemical synaptic transmission protein targeting regulation of protein stability regulation of synaptic plasticity |
exocytosis inner ear development maintenance of epithelial cell apical/basal polarity neurotransmitter secretion protein localization to basolateral plasma membrane protein transport protein-containing complex assembly synaptic vesicle transport |
intracellular protein transport protein import into mitochondrial matrix protein targeting to mitochondrion |
actin cytoskeleton organization actin filament bundle assembly anatomical structure morphogenesis cell migration establishment or maintenance of cell polarity eye photoreceptor cell development visual perception |
chromosome organization internal protein amino acid acetylation nucleosome assembly subtelomeric heterochromatin formation |
cell recognition immune response immune response-activating cell surface receptor signaling pathway inflammatory response natural killer cell activation positive regulation of natural killer cell mediated cytotoxicity |
innate immune response ISG15-protein conjugation protein modification process protein polyubiquitination ubiquitin-dependent protein catabolic process |
calcium ion import cell adhesion establishment of localization in cell negative regulation of cell-matrix adhesion negative regulation of cellular response to growth factor stimulus negative regulation of keratinocyte proliferation negative regulation of wound healing phosphorylation positive regulation of calcium ion import positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion regulation of synaptic vesicle exocytosis |
cytoskeleton organization Fc-gamma receptor signaling pathway involved in phagocytosis phosphatidic acid biosynthetic process phospholipid catabolic process regulation of vesicle-mediated transport small GTPase mediated signal transduction synaptic vesicle recycling |
cellular response to heat negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
regulation of cell shape |
cardiac muscle contraction cellular response to caffeine detection of calcium ion intracellular calcium ion homeostasis negative regulation of potassium ion transmembrane transporter activity negative regulation of potassium ion transport negative regulation of ryanodine-sensitive calcium-release channel activity protein polymerization Purkinje myocyte to ventricular cardiac muscle cell signaling regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of cell communication by electrical coupling regulation of heart rate regulation of membrane repolarization regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum sequestering of calcium ion striated muscle contraction |
chemotaxis skeletal system development |
endocytic recycling endosomal transport macroautophagy membrane fission membrane invagination multivesicular body assembly negative regulation of angiogenesis negative regulation of cell population proliferation negative regulation of platelet-derived growth factor receptor signaling pathway negative regulation of receptor signaling pathway via JAK-STAT negative regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of exosomal secretion positive regulation of gene expression protein localization to membrane protein targeting to lysosome protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway receptor internalization regulation of MAP kinase activity regulation of protein catabolic process signal transduction |
cell differentiation Golgi organization intracellular protein transport melanosome organization mitochondrion organization modulation by host of viral process negative regulation of neuron projection development positive regulation of intracellular protein transport positive regulation of receptor recycling positive regulation of T cell receptor signaling pathway protein localization to ciliary membrane protein localization to membrane regulation of retrograde transport, endosome to Golgi response to bacterium retrograde transport, endosome to Golgi synapse assembly T cell activation toxin transport |
binding of sperm to zona pellucida protein folding protein-containing complex assembly single fertilization ubiquitin-dependent ERAD pathway |
bile acid biosynthetic process fatty acid alpha-oxidation fatty acid beta-oxidation fatty-acyl-CoA biosynthetic process long-chain fatty acid import into cell long-chain fatty acid metabolic process methyl-branched fatty acid metabolic process very long-chain fatty acid catabolic process |
negative regulation of protein catabolic process positive regulation of polyamine transmembrane transport putrescine biosynthetic process from ornithine |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II |
regulation of gene expression RNA processing |
phosphatidylinositol biosynthetic process phosphatidylinositol phosphate biosynthetic process phosphorylation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
neurotransmitter secretion regulation of synaptic transmission, GABAergic synaptic vesicle clustering |
apoptotic process negative regulation of apoptotic process protein K11-linked ubiquitination protein K33-linked ubiquitination protein polyubiquitination protein ubiquitination regulation of inflammatory response ubiquitin-dependent protein catabolic process |
axon guidance branching involved in blood vessel morphogenesis gonadotrophin-releasing hormone neuronal migration to the hypothalamus negative chemotaxis negative regulation of angiogenesis negative regulation of axon extension involved in axon guidance negative regulation of cell-matrix adhesion negative regulation of neuron apoptotic process neural crest cell migration positive regulation of cell migration positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of cell shape semaphorin-plexin signaling pathway sprouting angiogenesis synapse organization |
negative regulation of transcription by RNA polymerase II regulation of cytokine production regulation of immune system process |
negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
anterograde axonal transport anterograde dendritic transport of neurotransmitter receptor complex cilium assembly determination of left/right symmetry intraciliary transport microtubule-based movement mitotic centrosome separation mitotic spindle assembly mitotic spindle organization opsin transport plus-end-directed vesicle transport along microtubule positive regulation of cytokinesis vesicle-mediated transport |
axon extension central nervous system development central nervous system projection neuron axonogenesis dendrite morphogenesis endosomal transport forebrain development intracellular signal transduction negative regulation of protein localization to nucleus nervous system development neuron migration neuron projection morphogenesis protein localization to nucleus protein phosphorylation response to virus |
neuron differentiation neurotransmitter secretion synaptic vesicle docking |
maintenance of presynaptic active zone structure neuromuscular synaptic transmission regulation of calcium-dependent activation of synaptic vesicle fusion regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic plasticity synaptic vesicle priming |
mitochondrial tRNA 5'-end processing tRNA 5'-leader removal |
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