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deadenylation-dependent decapping of nuclear-transcribed mRNA histone mRNA catabolic process mRNA processing negative regulation of neuron differentiation neuron differentiation RNA splicing RNA splicing, via transesterification reactions stem cell population maintenance |
immune response integrin-mediated signaling pathway protein localization to plasma membrane T cell receptor signaling pathway |
CDP-diacylglycerol biosynthetic process epidermis development phosphatidic acid biosynthetic process phospholipid metabolic process positive regulation of cytokine production positive regulation of cytokine-mediated signaling pathway response to xenobiotic stimulus triglyceride biosynthetic process |
ceramide biosynthetic process myelin maintenance sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process |
angiogenesis animal organ regeneration cellular response to growth factor stimulus gene expression germ cell development glomerulus vasculature development maternal process involved in female pregnancy negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of cell-substrate adhesion negative regulation of positive chemotaxis positive regulation of angiogenesis response to activity response to glucose response to hypoxia response to mechanical stimulus response to organic cyclic compound signal transduction Tie signaling pathway |
endocytosis establishment of localization in cell exocytosis post-Golgi vesicle-mediated transport protein transport |
chemical synaptic transmission excitatory postsynaptic potential neuropeptide signaling pathway |
NLS-bearing protein import into nucleus protein import into nucleus |
Arp2/3 complex-mediated actin nucleation response to estradiol response to estrogen |
actin filament polymerization actin polymerization-dependent cell motility Arp2/3 complex-mediated actin nucleation positive regulation of actin filament polymerization positive regulation of lamellipodium assembly positive regulation of substrate adhesion-dependent cell spreading |
actin polymerization-dependent cell motility Arp2/3 complex-mediated actin nucleation cellular response to nerve growth factor stimulus regulation of actin filament polymerization |
cell differentiation memory neuromuscular junction development positive regulation of gene expression positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of protein geranylgeranylation positive regulation of protein phosphorylation protein autophosphorylation regulation of synaptic assembly at neuromuscular junction skeletal muscle acetylcholine-gated channel clustering transmembrane receptor protein tyrosine kinase signaling pathway |
atrial septum development atrioventricular valve morphogenesis cellular response to hypoxia DNA damage response, signal transduction by p53 class mediator endocardial cushion morphogenesis heart valve development negative regulation of apoptotic process negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of protein catabolic process negative regulation of transcription by RNA polymerase II protein stabilization protein ubiquitination protein-containing complex assembly regulation of cell cycle ventricular septum development |
endoplasmic reticulum to Golgi vesicle-mediated transport protein transport vesicle fusion with Golgi apparatus |
adaptive thermogenesis ectoderm development lactation negative regulation of CD8-positive, alpha-beta T cell differentiation negative regulation of gene expression negative regulation of NK T cell proliferation negative regulation of T-helper 17 cell differentiation negative regulation of transcription by RNA polymerase II NK T cell differentiation positive regulation of brown fat cell differentiation positive regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of cold-induced thermogenesis positive regulation of gene expression positive regulation of insulin receptor signaling pathway positive regulation of interleukin-17 production positive regulation of SREBP signaling pathway regulation of transcription by RNA polymerase II response to insulin transcription by RNA polymerase II |
transcription by RNA polymerase I |
acute-phase response apoptotic process defense response to virus negative regulation of phagocytosis negative regulation of viral genome replication phosphatidylserine biosynthetic process phosphatidylserine exposure on apoptotic cell surface plasma membrane phospholipid scrambling platelet activation positive regulation of chromosome separation positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity positive regulation of gene expression positive regulation of innate immune response positive regulation of transcription by RNA polymerase II regulation of Fc receptor mediated stimulatory signaling pathway regulation of mast cell activation response to interferon-beta response to lead ion |
negative regulation of cell migration negative regulation of epithelial to mesenchymal transition negative regulation of SMAD protein signal transduction negative regulation of transforming growth factor beta receptor signaling pathway |
adipose tissue development |
anterior/posterior axis specification, embryo cardiac muscle cell myoblast differentiation cell fate specification heart morphogenesis mesoderm development mesoderm formation negative regulation of DNA-binding transcription factor activity negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II primitive streak formation regulation of transcription by RNA polymerase II signal transduction somitogenesis |
cell division centrosome cycle mRNA transport protein transport |
negative regulation of G1/S transition of mitotic cell cycle negative regulation of protein phosphorylation |
actin filament severing actin polymerization or depolymerization barbed-end actin filament capping |
axon guidance ephrin receptor signaling pathway |
anatomical structure morphogenesis BMP signaling pathway cell differentiation cellular response to BMP stimulus positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II SMAD protein signal transduction transforming growth factor beta receptor signaling pathway |
immune response negative regulation of cell adhesion proteolysis |
aggresome assembly myeloid dendritic cell differentiation positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction protein modification by small protein conjugation protein ubiquitination proteolysis regulation of mitotic cell cycle phase transition response to tumor necrosis factor response to type II interferon ubiquitin-dependent protein catabolic process |
regulation of transcription by RNA polymerase II |
negative regulation of cardiac muscle cell apoptotic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction Ras protein signal transduction regulation of Ral protein signal transduction |
chaperone-mediated protein complex assembly chaperone-mediated protein folding negative regulation of amyloid fibril formation protein folding protein stabilization |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit biogenesis |
glutathione metabolic process xenobiotic metabolic process |
negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II |
cerebellum morphogenesis ether lipid biosynthetic process fatty acid metabolic process membrane organization paranodal junction assembly phosphatidic acid biosynthetic process phospholipid biosynthetic process response to fatty acid response to nutrient response to starvation response to xenobiotic stimulus synapse assembly triglyceride biosynthetic process |
de novo' NAD biosynthetic process from tryptophan anthranilate metabolic process cellular response to interleukin-1 cellular response to lipopolysaccharide kynurenic acid biosynthetic process kynurenine metabolic process L-kynurenine metabolic process NAD metabolic process positive regulation of glutamate secretion, neurotransmission quinolinate biosynthetic process response to salt stress tryptophan catabolic process |
cartilage development extracellular matrix organization skeletal system development |
intracellular mRNA localization mRNA export from nucleus mRNA splicing, via spliceosome nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of translation |
carbohydrate homeostasis defense response to bacterium generation of precursor metabolites and energy glucose homeostasis insulin secretion ovarian follicle development regulation of neuronal synaptic plasticity regulation of synaptic plasticity response to cAMP response to cold response to dietary excess response to insulin sexual reproduction synaptic signaling via neuropeptide |
late endosome to vacuole transport via multivesicular body sorting pathway negative regulation of growth hormone receptor signaling pathway negative regulation of protein localization to cell surface negative regulation of receptor signaling pathway via JAK-STAT positive regulation of protein targeting to mitochondrion |
acetylcholine transport activation of cysteine-type endopeptidase activity involved in apoptotic process amine transport amino acid import across plasma membrane body fluid secretion choline transport dopamine transport dopamine uptake epinephrine transport export across plasma membrane histamine transport histamine uptake L-alpha-amino acid transmembrane transport L-arginine import across plasma membrane monoatomic cation transport neurotransmitter transport norepinephrine transport norepinephrine uptake organic cation transport positive regulation of gene expression prostaglandin transport purine-containing compound transmembrane transport putrescine transport serotonin transport serotonin uptake spermidine transport thiamine transmembrane transport toxin transport transport across blood-brain barrier xenobiotic transport xenobiotic transport across blood-brain barrier |
acetylcholine transport acyl carnitine transmembrane transport dopamine transport dopamine uptake epinephrine transport establishment or maintenance of transmembrane electrochemical gradient metanephric proximal tubule development monoamine transport neurotransmitter transport norepinephrine transport organic cation transport prostaglandin transport purine-containing compound transmembrane transport putrescine transport quaternary ammonium group transport serotonin transport serotonin uptake spermidine transport thiamine transmembrane transport thiamine transport toxin transport transport across blood-brain barrier xenobiotic metabolic process xenobiotic transport xenobiotic transport across blood-brain barrier |
chloride transport negative regulation of ryanodine-sensitive calcium-release channel activity positive regulation of binding regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum signal transduction |
fatty acid beta-oxidation using acyl-CoA oxidase lipid homeostasis |
positive regulation of protein localization to plasma membrane protein retention in ER lumen retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum skeletal muscle acetylcholine-gated channel clustering |
actin cytoskeleton organization cell projection organization cell-cell adhesion positive regulation of bicellular tight junction assembly protein localization involved in establishment of planar polarity retina development in camera-type eye signal transduction spermatid differentiation visual behavior |
Golgi organization lipid homeostasis lipoprotein transport positive regulation of organelle organization regulation of lipid transport |
antifungal innate immune response antimicrobial humoral immune response mediated by antimicrobial peptide cell chemotaxis chemotaxis defense response to bacterium defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium G protein-coupled receptor signaling pathway immune response killing of cells of another organism |
cell cycle cellular response to anisomycin cellular response to hydrogen peroxide cellular response to interleukin-1 cellular response to sodium arsenite cellular response to sorbitol cellular response to UV intracellular signal transduction peptidyl-serine phosphorylation positive regulation of inflammatory response positive regulation of interleukin-6 production response to osmotic stress stress-activated MAPK cascade |
positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II skeletal system development |
ceramide biosynthetic process positive regulation of lipophagy regulation of fat cell apoptotic process sphinganine biosynthetic process sphingolipid biosynthetic process sphingolipid metabolic process sphingomyelin biosynthetic process sphingosine biosynthetic process |
adipose tissue development ceramide biosynthetic process positive regulation of lipophagy sphinganine biosynthetic process sphingolipid biosynthetic process sphingomyelin biosynthetic process sphingosine biosynthetic process |
adult heart development cardiac muscle cell development cardiac muscle contraction cardiac muscle hypertrophy cardiac muscle hypertrophy in response to stress cardiac muscle tissue morphogenesis cardiac myofibril assembly detection of mechanical stimulus detection of muscle stretch otic vesicle formation protein-containing complex assembly response to muscle stretch sarcomere organization sarcomerogenesis skeletal muscle contraction skeletal muscle myosin thick filament assembly skeletal muscle thin filament assembly somitogenesis |
DNA damage response DNA repair interstrand cross-link repair mitochondrion organization ovarian follicle development response to radiation spermatid development |
apoptotic process arachidonic acid metabolic process cannabinoid biosynthetic process endocannabinoid signaling pathway hepoxilin biosynthetic process linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxygenase pathway negative regulation of cell cycle negative regulation of cell migration negative regulation of cell population proliferation negative regulation of growth phospholipid metabolic process positive regulation of chemokine production positive regulation of keratinocyte differentiation positive regulation of macrophage derived foam cell differentiation positive regulation of peroxisome proliferator activated receptor signaling pathway prostate gland development regulation of epithelial cell differentiation |
cellular response to starvation DNA damage response, signal transduction by p53 class mediator DNA methylation G2/M transition of mitotic cell cycle heterochromatin formation negative regulation of cell population proliferation negative regulation of gene expression, epigenetic peptidyl-threonine dephosphorylation protein dephosphorylation regulation of transcription initiation by RNA polymerase II response to bacterium response to radiation |
chemical synaptic transmission detection of light stimulus involved in visual perception detection of visible light G protein-coupled glutamate receptor signaling pathway locomotory behavior positive regulation of calcium ion import across plasma membrane regulation of synaptic transmission, glutamatergic retina development in camera-type eye |
activation-induced cell death of T cells extrinsic apoptotic signaling pathway intrinsic apoptotic signaling pathway negative regulation of NF-kappaB transcription factor activity positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway |
GDP-mannose biosynthetic process mannose metabolic process protein glycosylation protein N-linked glycosylation |
blastocyst growth DNA recombination DNA repair double-strand break repair via homologous recombination positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle reciprocal meiotic recombination somite development |
cell population proliferation defense response to virus innate immune response positive regulation of innate immune response positive regulation of interferon-beta production regulation of transcription by RNA polymerase III transcription by RNA polymerase III |
inositol phosphate metabolic process phosphatidylinositol biosynthetic process phosphatidylinositol dephosphorylation signal transduction |
proton transmembrane transport regulation of macroautophagy transmembrane transport vacuolar acidification |
microtubule cytoskeleton organization negative regulation of microtubule depolymerization pattern specification process positive regulation of stress-activated MAPK cascade protein localization to microtubule regulation of microtubule cytoskeleton organization |
DNA geometric change DNA recombination innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation regulation of transcription by RNA polymerase II |
cell cycle DNA damage response intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator kidney development mismatch repair negative regulation of cardiac muscle cell proliferation negative regulation of cell population proliferation negative regulation of neuron differentiation positive regulation of apoptotic process positive regulation of DNA-templated transcription positive regulation of lung ciliated cell differentiation positive regulation of MAPK cascade positive regulation of oligodendrocyte differentiation positive regulation of transcription by RNA polymerase II protein tetramerization regulation of cell cycle regulation of gene expression regulation of mitotic cell cycle regulation of transcription by RNA polymerase II response to organonitrogen compound response to xenobiotic stimulus |
animal organ morphogenesis blood vessel morphogenesis defense response epidermis development hair follicle development keratinocyte differentiation lymphoid lineage cell migration into thymus nail development positive regulation of epithelial cell differentiation positive regulation of hair follicle development regulation of positive thymic T cell selection regulation of transcription by RNA polymerase II T cell homeostasis T cell lineage commitment thymus epithelium morphogenesis |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cellular response to reactive oxygen species dendrite development dopamine biosynthetic process G protein-coupled receptor signaling pathway locomotion involved in locomotory behavior neuropeptide signaling pathway positive regulation of dopamine metabolic process positive regulation of MAPK cascade |
peptidyl-threonine dephosphorylation protein dephosphorylation regulation of cell cycle |
cap-dependent translational initiation formation of cytoplasmic translation initiation complex IRES-dependent viral translational initiation positive regulation of mRNA binding positive regulation of translation translational initiation viral translational termination-reinitiation |
formation of cytoplasmic translation initiation complex negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of translational initiation translational initiation |
monocarboxylic acid transport |
positive regulation of protein binding positive regulation of telomerase activity regulation of protein localization to nucleolus ribosomal large subunit biogenesis ribosome biogenesis rRNA processing |
branched-chain amino acid biosynthetic process cellular response to leukemia inhibitory factor isoleucine catabolic process leucine biosynthetic process lipid metabolic process regulation of hormone levels valine biosynthetic process |
cell adhesion |
positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II |
apoptotic process cell division establishment of chromosome localization G2/M transition of mitotic cell cycle mitotic cell cycle mitotic cytokinesis mitotic spindle assembly mitotic spindle assembly checkpoint signaling mitotic spindle midzone assembly negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA-templated transcription positive regulation of attachment of mitotic spindle microtubules to kinetochore positive regulation of cell population proliferation positive regulation of exit from mitosis positive regulation of mitotic cell cycle positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic cytokinesis positive regulation of mitotic sister chromatid separation protein phosphorylation protein-containing complex localization sensory perception of sound |
positive regulation of viral entry into host cell protein autoprocessing proteolysis viral translation |
axonal fasciculation neuron cell-cell adhesion |
intracellular protein transport organelle assembly organelle localization positive regulation of receptor localization to synapse positive regulation of T cell mediated cytotoxicity regulation of protein localization to plasma membrane vesicle docking vesicle fusion |
apoptotic process negative regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II regulation of apoptotic process regulation of transcription by RNA polymerase II |
caudate nucleus development cerebral cortex development negative regulation of DNA-templated transcription putamen development regulation of transcription by RNA polymerase II |
lactate transmembrane transport monocarboxylic acid transport protein catabolic process pyruvate catabolic process pyruvate transmembrane transport |
angiogenesis copper ion import copper ion transport establishment of localization in cell intracellular copper ion homeostasis plasma membrane copper ion transport protein complex oligomerization silver ion transmembrane transport vascular endothelial growth factor receptor-2 signaling pathway xenobiotic transport |
copper ion import copper ion transport intracellular copper ion homeostasis regulation of copper ion transmembrane transport |
cell chemotaxis cell surface receptor signaling pathway cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled receptor signaling pathway immune response inflammatory response lymphocyte chemotaxis monocyte chemotaxis negative regulation of leukocyte tethering or rolling neutrophil chemotaxis positive regulation of cell-matrix adhesion positive regulation of ERK1 and ERK2 cascade |
rRNA transcription transcription by RNA polymerase I transmembrane receptor protein tyrosine kinase signaling pathway |
female gamete generation homologous chromosome pairing at meiosis mismatch repair ovarian follicle development reciprocal meiotic recombination spermatogenesis |
carbohydrate metabolic process glycosphingolipid biosynthetic process N-glycan processing oligosaccharide metabolic process protein glycosylation |
cell communication cell-cell signaling cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to type II interferon chemokine-mediated signaling pathway chemotaxis eosinophil chemotaxis G protein-coupled receptor signaling pathway inflammatory response lymphocyte chemotaxis monocyte chemotaxis neutrophil chemotaxis positive regulation of ERK1 and ERK2 cascade |
proteolysis signal transduction |
glycogen biosynthetic process |
G protein-coupled receptor signaling pathway negative regulation of signal transduction positive regulation of GTPase activity regulation of G protein-coupled receptor signaling pathway visual perception |
endoplasmic reticulum to Golgi vesicle-mediated transport protein transport retrograde transport, endosome to Golgi vesicle docking involved in exocytosis vesicle targeting |
anatomical structure morphogenesis regulation of transcription by RNA polymerase II |
cellular response to insulin stimulus cellular response to sterol cholesterol biosynthetic process cholesterol homeostasis cranial suture morphogenesis inner ear morphogenesis middle ear morphogenesis negative regulation of cargo loading into COPII-coated vesicle negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process negative regulation of protein exit from endoplasmic reticulum negative regulation of steroid biosynthetic process roof of mouth development SREBP signaling pathway SREBP-SCAP complex retention in endoplasmic reticulum triglyceride metabolic process |
mRNA transport nucleocytoplasmic transport protein export from nucleus |
actin cytoskeleton organization Arp2/3 complex-mediated actin nucleation cell migration regulation of actin filament polymerization |
recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter |
cellular response to ionizing radiation circadian regulation of gene expression circadian rhythm DNA damage checkpoint signaling negative regulation of DNA-templated transcription negative regulation of glucocorticoid receptor signaling pathway photoperiodism positive regulation of circadian rhythm positive regulation of DNA-templated transcription positive regulation of inflammatory response positive regulation of NF-kappaB transcription factor activity proteasome-mediated ubiquitin-dependent protein catabolic process protein acetylation regulation of circadian rhythm regulation of DNA-templated transcription regulation of hair cycle regulation of insulin secretion regulation of transcription by RNA polymerase II regulation of type B pancreatic cell development response to redox state signal transduction spermatogenesis |
axonogenesis cell differentiation DNA-templated transcription epithelial cell proliferation liver development lung development negative regulation of epithelial cell proliferation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II |
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