anchor
large_stringlengths 18
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| positive
large_stringlengths 0
284
| class
class label 3
classes |
|---|---|---|
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
chromosome, centric region
| 1cellular_component
|
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
chromosome, pericentric region
| 1cellular_component
|
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
condensed chromosome kinetochore
| 1cellular_component
|
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
condensed nuclear chromosome kinetochore
| 1cellular_component
|
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
NMS complex
| 1cellular_component
|
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
condensed chromosome, centric region
| 1cellular_component
|
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
condensed chromosome, centromere
| 1cellular_component
|
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
condensed chromosome, pericentric region
| 1cellular_component
|
The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
condensed nuclear chromosome, centromeric region
| 1cellular_component
|
The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).
|
nuclear chromosome, telomere
| 1cellular_component
|
The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).
|
nuclear chromosome, telomeric region
| 1cellular_component
|
The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).
|
telomere
| 1cellular_component
|
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
chromosome scaffold
| 1cellular_component
|
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
cytoplasmic chromatin
| 1cellular_component
|
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
nuclear chromatin
| 1cellular_component
|
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
|
cytoplasmic nucleosome
| 1cellular_component
|
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
|
nuclear nucleosome
| 1cellular_component
|
A compact and highly condensed form of chromatin that is refractory to transcription.
|
nuclear heterochromatin
| 1cellular_component
|
A compact and highly condensed form of chromatin that is refractory to transcription.
|
transcriptionally inactive chromatin
| 1cellular_component
|
A compact and highly condensed form of chromatin that is refractory to transcription.
|
transcriptionally silent chromatin
| 1cellular_component
|
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
cytoplasmic mitotic chromosome
| 1cellular_component
|
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
metaphase chromosome
| 1cellular_component
|
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
|
mitotic chromosome
| 1cellular_component
|
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
meiotic chromosome
| 1cellular_component
|
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
|
nuclear mitotic chromosome
| 1cellular_component
|
A multisubunit complex that is located at the replication origins of a chromosome.
|
ORC
| 1cellular_component
|
A multisubunit complex that is located at the replication origins of a chromosome.
|
origin of replication recognition complex
| 1cellular_component
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
|
regulation of glutamine family amino acid metabolism
| 0biological_process
|
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
|
regulation of arginine metabolism
| 0biological_process
|
Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
|
IP6 kinase
| 2molecular_function
|
Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
|
inositol heptakisphosphate kinase activity
| 2molecular_function
|
Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
|
PP-IP5 kinase activity
| 2molecular_function
|
A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
|
HRD1 ubiquitin ligase complex
| 1cellular_component
|
The developmental process in which the size or shape of a cell is generated and organized.
|
cellular morphogenesis
| 0biological_process
|
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
|
ascus development
| 0biological_process
|
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
|
fruiting body development involved in sexual reproduction
| 0biological_process
|
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
|
fruiting body formation involved in sexual reproduction
| 0biological_process
|
The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
|
perfect stage fruiting body development
| 0biological_process
|
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
|
cell cycle cytokinesis
| 0biological_process
|
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
|
cytokinesis involved in cell cycle
| 0biological_process
|
The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
actomyosin apparatus assembly involved in cytokinesis
| 0biological_process
|
The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, formation of actomyosin apparatus
| 0biological_process
|
The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
formation of actomyosin apparatus involved in cytokinesis
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
constriction ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
contractile ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, actomyosin contractile ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, actomyosin contractile ring formation
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, actomyosin ring biosynthesis
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, actomyosin ring formation
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
cytokinesis, contractile ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
myosin filament organization involved in cytokinetic actomyosin contractile ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
myosin filament organization of constriction ring assembly
| 0biological_process
|
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
myosin filament organization of contractile ring assembly
| 0biological_process
|
The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
|
actomyosin contractile ring constriction
| 0biological_process
|
The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
|
contractile ring contraction involved in cell cycle cytokinesis
| 0biological_process
|
The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
|
cytokinesis, actomyosin ring contraction
| 0biological_process
|
The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
|
cytokinesis, contractile ring contraction
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum assembly involved in cell cycle cytokinesis
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum formation
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum formation involved in cell cycle cytokinesis
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
division septum formation involved in mitotic cell cycle
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
formation of division septum
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
formation of division septum involved in mitotic cell cycle
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
mitotic division septum assembly
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
septation
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
septin assembly and septum biosynthesis
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
septin assembly and septum biosynthesis involved in mitotic cell cycle
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
septin assembly and septum formation
| 0biological_process
|
The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
|
septin assembly and septum formation involved in mitotic cell cycle
| 0biological_process
|
The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.
|
cell plate formation
| 0biological_process
|
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
|
cell separation after cytokinesis
| 0biological_process
|
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
|
cell separation following cytokinesis
| 0biological_process
|
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
|
cytokinetic cell separation
| 0biological_process
|
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
|
daughter cell separation
| 0biological_process
|
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
|
mitotic cytokinetic cell separation
| 0biological_process
|
The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
|
septin assembly and septum biosynthesis
| 0biological_process
|
The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
|
septin assembly and septum formation
| 0biological_process
|
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
cytoplasmic foci
| 1cellular_component
|
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
cytoplasmic mRNA processing body
| 1cellular_component
|
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
P body
| 1cellular_component
|
A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.
|
porous septum
| 1cellular_component
|
A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
|
cell septum surface
| 1cellular_component
|
A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
|
complete septum
| 1cellular_component
|
A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
|
septum surface
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
condensed chromosome inner kinetochore
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
condensed nuclear chromosome inner kinetochore
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
inner centromere core complex
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
inner kinetochore of condensed chromosome
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
inner kinetochore of condensed nuclear chromosome
| 1cellular_component
|
The region of a kinetochore closest to centromeric DNA which contains many CENP proteins organized in various subcomplexes including CENP-C, CENP-LN, CENP-HIKM, CENP-OPQUR and CENP-TWSX, but excluding the CENP-A containing heterochromatin.
|
inner kinetochore plate
| 1cellular_component
|
The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
condensed chromosome outer kinetochore
| 1cellular_component
|
The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
condensed nuclear chromosome outer kinetochore
| 1cellular_component
|
The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
outer kinetochore of condensed chromosome
| 1cellular_component
|
The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
outer kinetochore of condensed nuclear chromosome
| 1cellular_component
|
The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
outer kinetochore plate
| 1cellular_component
|
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
nuclear mRNA breakdown
| 0biological_process
|
The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
|
nuclear mRNA catabolism
| 0biological_process
|
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