anchor
large_stringlengths 18
1.31k
| positive
large_stringlengths 0
284
| class
class label 3
classes |
|---|---|---|
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
|
maintenance of transcriptional fidelity during DNA-dependent transcription elongation
| 0biological_process
|
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
|
maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter
| 0biological_process
|
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
|
maintenance of transcriptional fidelity during DNA-templated transcription elongation
| 0biological_process
|
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
|
maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter
| 0biological_process
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding
| 2molecular_function
|
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.
|
transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type DNA binding transcription repressor activity
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding
| 2molecular_function
|
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.
|
transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding
| 2molecular_function
|
Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
RNA polymerase II transcription cofactor binding
| 2molecular_function
|
Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
RNA polymerase II transcription coregulator binding
| 2molecular_function
|
Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
transcription cofactor binding
| 2molecular_function
|
Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
|
assembly of extrachromosomal circular DNA
| 0biological_process
|
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
|
colony morphology
| 0biological_process
|
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
skeletal development
| 0biological_process
|
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
bone biosynthesis
| 0biological_process
|
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
bone formation
| 0biological_process
|
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
osteogenesis
| 0biological_process
|
The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
|
neurotransmitter import
| 0biological_process
|
The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
|
neurotransmitter import into glial cell
| 0biological_process
|
The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
|
neurotransmitter import into neuron
| 0biological_process
|
The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
|
neurotransmitter recycling
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
prostaglandin anabolism
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
prostaglandin biosynthesis
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
prostaglandin formation
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
|
prostaglandin synthesis
| 0biological_process
|
The intramolecular conversion of uridine to pseudouridine within an RNA molecule.
|
pseudouridylation
| 0biological_process
|
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
|
retinoid metabolism
| 0biological_process
|
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
blood vessel formation from pre-existing blood vessels systematic_synonym
| 0biological_process
|
Protein complex forming portion of the radial spoke that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary or flagellum axoneme.
|
radial spokehead
| 1cellular_component
|
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
|
ciliary or bacterial-type flagellar motility
| 0biological_process
|
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
|
ciliary/flagellar motility
| 0biological_process
|
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
follicular phase
| 0biological_process
|
The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.
|
ovarian follicle antrum/follicular fluid biosynthesis
| 0biological_process
|
The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.
|
ovarian follicle antrum/follicular fluid formation
| 0biological_process
|
The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.
|
ovarian cumulus cell differentiation
| 0biological_process
|
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
|
luteal phase
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
|
resistance to pathogenic protozoa
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
|
response to protozoa
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
|
response to protozoon
| 0biological_process
|
The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
|
patterning of blood vessels
| 0biological_process
|
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
|
vascular morphogenesis
| 0biological_process
|
The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
ganglioside metabolism
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
ganglioside anabolism
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
ganglioside biosynthesis
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
ganglioside formation
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
ganglioside synthesis
| 0biological_process
|
The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
|
globoside metabolism
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
|
globoside anabolism
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
|
globoside biosynthesis
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
|
globoside formation
| 0biological_process
|
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
|
globoside synthesis
| 0biological_process
|
A process that results in a parallel arrangement of microtubules.
|
microtubule bundling
| 0biological_process
|
Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
P2 receptor
| 2molecular_function
|
Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
purinergic receptor activity
| 2molecular_function
|
Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
purinoceptor
| 2molecular_function
|
Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
purinoreceptor
| 2molecular_function
|
Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
G protein chemoattractant receptor activity
| 2molecular_function
|
Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
G-protein chemoattractant receptor activity
| 2molecular_function
|
Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
G-protein coupled chemoattractant receptor activity
| 2molecular_function
|
Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
|
adenylate cyclase inhibiting metabotropic glutamate receptor activity
| 2molecular_function
|
Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
|
adenylyl cyclase inhibiting metabotropic glutamate receptor activity
| 2molecular_function
|
A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.
|
protease-activated receptor activity
| 2molecular_function
|
A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.
|
proteinase activated receptor activity
| 2molecular_function
|
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
osteoblast cell differentiation
| 0biological_process
|
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
|
endogenous peptide receptor activity
| 2molecular_function
|
Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
|
exogenous peptide receptor activity
| 2molecular_function
|
The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
ureteric bud branching
| 0biological_process
|
A homeostatic process in which an organism modulates its internal body temperature.
|
thermoregulation
| 0biological_process
|
The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.
|
pyrexia
| 0biological_process
|
An acute behavioral change resulting from a perceived external threat.
|
behavioural fear response
| 0biological_process
|
Binding to a G protein-coupled receptor.
|
G protein coupled receptor binding
| 2molecular_function
|
Binding to a G protein-coupled receptor.
|
G protein coupled receptor ligand
| 2molecular_function
|
Binding to a G protein-coupled receptor.
|
G-protein coupled receptor binding
| 2molecular_function
|
Binding to a G protein-coupled receptor.
|
G-protein-coupled receptor ligand
| 2molecular_function
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
response to hypoxic stress
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
response to intermittent hypoxia
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
response to lowered oxygen tension
| 0biological_process
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
response to sustained hypoxia
| 0biological_process
|
Cell migration that is accomplished by extension and retraction of a pseudopodium.
|
ameboid cell migration
| 0biological_process
|
Cell migration that is accomplished by extension and retraction of a pseudopodium.
|
amoeboid cell migration
| 0biological_process
|
Cell migration that is accomplished by extension and retraction of a pseudopodium.
|
amoeboidal cell migration
| 0biological_process
|
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
|
acrosomal granule
| 1cellular_component
|
A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
|
acrosome
| 1cellular_component
|
Binds to and increases the activity of an ATP hydrolysis activity.
|
ATPase stimulator activity
| 2molecular_function
|
The nucleus of a male germ cell, a reproductive cell in males.
|
male germ-cell nucleus
| 1cellular_component
|
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