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Clozapine treatment of borderline patients: a preliminary study.
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Fatal pulmonary fibrosis induced by paclitaxel: a case report and review of the literature.
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Using anti-CD79a as a B-cell marker is mandatory to overcome the difficulties in identifying these tumors.
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CONCLUSIONS: The tumor in the reported case may have enlarged in response to orally ingested sex steroid pills.
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Neurological manifestations in patient 1 could be due to hypertension secondary to IVPMP, while the pathogenesis of such manifestations remained difficult to clarify in patient 2.
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The second author concurs with use of Silvadene cream and would avoid any pressure on the area (Dr.
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It seems that being aware of the undesirable affects of tamoxifen treatment during the chemotherapy and post-chemotherapy period is very important.
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Rapamycin/sirolimus (SR), trade named Rapammune (Wyeth-Ayerst, Sydney, Australia), is a potent immunosuppressive drug associated with myelosuppression, hypertension, hyperlipidemia, and infection.
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Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome.
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Albuterol-induced hypokalemia and its potential cardiac toxicity are discussed briefly.
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We, therefore, recommend a trial of HU for thalassemia intermedia patients in whom chronic transfusion therapy is being contemplated.
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Thalidomide neuropathy is often associated with proximal weakness and may progress even after discontinuation of treatment, in the phenomenon of 'coasting'.
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The patient's arthritis flared after the second infusion of infliximab, which was discontinued.
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This resulted in clearance of the virus from the AF and the delivery of a healthy newborn girl, free of CMV disease.
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Peripheral nervous system disturbances caused by cytosine arabinoside have rarely been reported.
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Severe hypernatraemia associated with growth hormone replacement therapy in a patient with septo-optic dysplasia.
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A proposed management scheme is detailed, including intravenously-administered propranolol as the preferred first-line antiarrhythmic agent.
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Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia.
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Whether the simultaneous administration of ciprofloxacin or tazobactam/piperacillin increases the risk of thrombocytosis is unknown.
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He was well and his serum creatinine was 1.0 mg/dl at 22 years of age.
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Naloxone administration reversed the symptoms.
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This phenomenon mimics the extrarenal production of 1,25-dihydroxyvitamin D by activated alveolar macrophages in granulomatous diseases with hypercalcemia.
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Opioid drugs cause bile duct obstruction during hepatobiliary scans.
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The patient was successfully treated with early surgery and combination antifungal therapy.
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His VPA concentration at admission was 238 micromol/L, a 48% decrease.
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A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, lymphadenopathy, hepatitis, hemolysis, leukopenia, and mononucleosis, has been described in patients treated with the drug for leprosy.
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This paper reports an autopsy case of a 78-year-old male with multiple nodules in the liver developed after long-termed administration of phosphate diethylstilbestrol (PDES) for prostatic cancer.
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It can mimic other diseases because of its nonspecific clinical presentation and radiographic signs.
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The inherited activity of the enzyme thiopurine methyltransferase has been recently recognised as a major factor in the susceptibility to myelosuppression.
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Discontinuation of chemotherapy, desensitization protocols and steroid premedication can be avoided.
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We conclude that these agents should be used with great care in patients in whom atherosclerotic vascular disease is likely.
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Diclofenac-associated hepatitis.
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These results suggest that clozapine may be an effective antipsychotic agent for this subset of BPD patients.
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Neuroleptic malignant syndrome is an uncommon and potentially fatal idiosynchratic reaction of antipsychotic drugs, in which the clinical scenario encompass muscular rigidity, hyperthermia, autonomic dysfunction, altered consciousness, high creatinine phosphokinase levels, and leukocytosis.
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RESULTS: A total of 178 cases were identified.
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Renal failure necessitated 5 hemodialysis sessions.
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Here, we report a case of acute liver dysfunction complicated with uncontrollable glycemia due to insulin antibody.
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Concern usually arises when a medication is added to a continuing regimen, though discontinuation of a medication can also have an impact.
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Positive immunohistochemistry staining of a biopsy specimen for cytomegalovirus suggested a viral etiology; however, lesions persisted despite antiviral therapy, and immunohistochemistry was negative on follow-up biopsy.
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PVT was diagnosed on colour Doppler ultrasonography (US).
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The changes were progressive regardless of discontinuation of cyclophosphamide and led to severe restrictive ventilatory defect.
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An Asian multiparous woman weighing 47 kg, who suffered from a rare myopathy, congenital fibre type disproportion, was given morphine 10 mg intramuscularly for labour analgesia.
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Imatinib is a selective tyrosine kinase inhibitor which acts on breakpoint cluster region-Abelson fusion gene (BCR-ABL) positive leukemia including all phases of chronic myeloid leukemia and acute lymphoblastic leukemia.
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In all patients, the administration of cisplatin instead of carboplatin was well tolerated without the need of premedication.
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However, the characteristic ultrasound appearance of both pathologies facilitates determination of the final diagnosis and further treatment.
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Proconvulsive tendency of imipenem/cilastatin is one of its well-known side effects.
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Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.
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This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome.
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This toxic effect may be added to the list of potential adverse events occurring during ddI therapy.
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A case of prolonged suxamethonium apnoea successfully terminated by the infusion of a commercial preparation of serumcholinesterase is reported.
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In the absence of clinical or morphologic differences, a recent ingestion of minocycline should be excluded before the diagnosis of sporadic autoimmune hepatitis is established.
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We report the case of an 87-year-old white woman with myasthenia gravis who presented with nausea, shortness of breath, azotemia, and hyperkalemia shortly after completing a course of intravenous immunoglobulin (IVIG).
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He began smoking again within 48 hours.
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In the presented case fluvoxamine-induced akathisia in an OCD patient was partially resistant to the anticholinergic agent biperiden, and was successfully treated with the 5-HT2A/5-HT2C antagonist mianserin.
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Complete remission of BOOP was achieved by long-term treatment with low-dose methotrexate (5-20 mg/week, i.v.).
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CK and/or alanine aminotransferase and aspartate aminotransferase were increased 5-24 times above the normal range in four of these patients, and the muscle biopsy showed focal RML in all five.
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RESULTS: Despite high pretreatment values of serum alanine aminotransferase (ALT; peak value of 901 IU/L) and HCV-RNA (2.3 x 10(6) copies/ml), the combination therapy with IFN and ribavirin produced a rapid normalization of the serum ALT values, accompanied by the clearance of serum HCV-RNA.
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Although the two local anesthetics usually do not cause methemoglobinemia, we suspect that the displacement of lidocaine from protein binding by bupivacaine, in combination with metabolic acidosis and treatment with other oxidants, was the reason for the development of methemoglobinemia.
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In addition, the patient tolerated other neuroleptics that were started in the hospital after the suspected NMS episode.
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In these patients, the action of tricyclics can be conceptualized as accelerating rather than counteracting the natural, cyclic course of the illness in all of its phases.
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Testing proved a severe type IV contact allergy restricted to budesonide (group B), without cross-reactions to major corticosteroids of other groups.
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F VIII concentrate was given concomitantly (50 IU/kg bw twice daily) during the initial phase of treatment.
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Alkylating agents have a well established role in the treatment of malignant disease, with well documented side effects.
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Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases.
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On the first day of the schedule, moderate high doses of Methotrexate, Etoposide and Cyclophosphamide were administered.
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The subjects received the urinary sediment test before and during the study for screening urinary tract infection and the study was discontinued when urinary tract infection was found.
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CASE SUMMARY: A 22-year-old male was admitted after a motor vehicle crash.
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Cushing's syndrome caused by unsupervised use of ocular glucocorticoids.
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Three patients (3 eyes) representing unresolved total hyphema for more than 5 days and uncontrolled high intraocular pressure received intracameral injections of 10 microgram of recombinant tPA.
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An ICD implantation was selected for the therapy since ventricular fibrillation was induced.
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PURPOSE: To report our experience with late vitritis associated with keratoprosthesis (KPro).
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Acute neuritis can lead to permanent nerve damage and necessitate prompt treatment with prednisone and/or clofazamine.
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BACKGROUND: We report six cases of psychosis in patients with akinetic-rigid syndromes who were treated with risperidone.
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Adverse reactions reported during cimetidine therapy were generally mild to moderate in severity and required discontinuance of therapy in only one patient.
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This unusual cutaneous sign may be the first sign of methotrexate toxicity.
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Chromoblastomycosis, or chromomycosis, is a chronic fungal infection of the skin and subcutaneous tissues caused by a species of dematiaceous fungi.
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Due to the escalating rates of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection, trimethoprim-sulfamethoxazole (TMP-SMX) is being used increasingly in the pediatric population for skin and soft tissue infections.
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This had been given systemically during the patient's last week of life.
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Fludarabine phosphate is currently proposed for the treatment of refractory chronic lymphocytic leukemia (CLL).
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Case report: lack of control of diabetes and weight gain in a patient on initiation and rechallenge of therapy with olanzapine.
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The increasing administration of protocol chemotherapy by practitioners in the community, who may not be especially familiar with the particular agents in a given regimen, suggests such errors may become more common.
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We present a depressive patient who developed mild parkinsonian signs and camptocormia after the introduction of olanzapine.
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Comeoscleral perforation after pterygium excision and intraoperative mitomycin C.
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We report a case of MMC-related hemolytic uremic syndrome, and discuss the etiologic parameters, clinical aspects, prognosis and treatment modalities of this severe syndrome.
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A case is described where a woman with major toxicity and high serum levels was managed without recourse to invasive modalities such as cardiopulmonary bypass or extracorporeal therapies.
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In summary, adenosine should be recognized as a potentially dangerous intervention in patients with atrial flutter.
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This patient adds to the growing literature of a second malignancy occurring after prolonged successful chemotherapy of a primary neoplasm.
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It can be caused by a variety of factors, including repeated steroid injections, chronic tenosynovitis, and decreased blood supply to the tendon.
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At 1 month the rabbits were killed and the eyes examined by light microscopy.
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After an interval of 3 months, he presented a complex pattern of nail hyperpigmentation, from combined dense horizontal and longitudinal streaks in some nails to diffuse black discoloration in others (Figure).
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Intravesical chemotherapy may be associated with a risk of secondary malignancy.
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E. avium bacteremias were polymicrobial in seven cases; in six cases, the coisolates were gastrointestinal organisms.
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Phenytoin was discontinued after admission; however, phenytoin 1 g i.v. was given for a tonic-clonic seizure two days after admission, after which swelling of the face and legs and pruritus developed.
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General aneurysmatosis due to cheese consumption: complications of an endocarditis caused by Lactococcus cremoris.
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The risk of massive cerebrospinal fluid overdrainage after repetitive manual pumping of the V-P shunt reservoir, which can contribute to the formation of a cerebellar hemorrhage, warrants special attention and hydrocephalic patients and their caregivers should be informed and educated about this potential complication.
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DESIGN: interventional case report.
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Reasonable precautions (regular but briefer and less vigorous brushing of her teeth) combined with a moderate dose of carbamazepine effectively prevented seizure recurrence.
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Therefore, parenteral amiodarone was implicated as the cause of acute hepatitis in this patient.
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Reversible cholestasis with bile duct injury following azathioprine therapy.
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CONCLUSION: Intraperitoneal catheters have a morbidity that persists after nonuse.
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