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RT can result in a multitude of adverse effects, both reversible and irreversible.
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A case of clozapine-induced tonic-clonic seizures managed with valproate: implications for clinical care.
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Kluyvera co-infection in two solid organ transplant recipients: an emerging pathogen or a colonizer bystander?
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Persistent right umbilical vein--case report and review of literature.
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A 27-year-old man with acute monoblastic leukemia had clinical and laboratory evidence of disseminated intravascular coagulation (DIC), which was exacerbated by induction chemotherapy.
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Improvement was dose-dependent, and was limited by irritability and action tremor when the patient was taking 1,600 mg per day.
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We report on case histories of two epileptic patients who were initially on lamotrigine and to whom sertraline was added to control psychiatric features.
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A 56-yr-old white female administered corticosteroids presented with left ear pain and facial swelling due to cervical subcutaneous emphysema from a diverticular perforation of the sigmoid colon.
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After administration of Oxybutynin concomitantly with an increase in the dose of Dantrolene, she presented the clinical symptoms and laboratory finding of Carbamazepine intoxication.
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Although the existence of an acute pericarditis or an acute myocarditis as possible causes of the ST elevation cannot be fully ruled out, the sudden onset, prominent magnitude, and brief duration of the ST elevation are perhaps more indicative of an acute ischemic event, possibly related to a transient coronary vasoconstriction induced by the dopamine infusion.
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A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate.
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At present, both patients are in the NYHA class I state and are ready to return to work.
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INTRODUCTION: We are reporting a case of bladder contracture post intravesical bacillus Calmette-Guerin (BCG) therapy; to our knowledge only two cases were reported.
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Morphological findings on sural nerve biopsies revealed both axonal degeneration and segmental remyelination.
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Diagnosis, therapy, and complications of therapy are discussed.
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Contrary to previous recommendations, our experience cautions against the further use of high-dose cytarabine in patients who develop PPE, and is a timely reminder of the potential toxicity of this agent, which is now increasingly being used as first-line treatment in the management of haematologic malignancies.
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Only 2 cases of spinal lipomatosis in HIV-related lipodystrophy have been reported.
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The critical care provider is faced with deducing the etiology and treatment of delirium in the ICU.
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OBJECTIVE: 1) To describe a patient with rheumatoid arthritis receiving adalimumab who developed fever, pancytopenia, splenomegaly, and extreme hyperferritinemia.
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CONCLUSION: Most GHD patients have intact posterior pituitary function.
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Epidural steroid injections are relatively safe procedures, although the risk of hemorrhagic complications in patients undergoing long-term anticoagulation therapy is higher.
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We report a case of acute generalized exanthematous pustulosis (AGEP) induced by salazosulfapyridine in a patient with ulcerative colitis.
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The patient remains free of both leukemia and fungal disease more than 4 years after transplant.
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Patients with cancer should be aware that alternative remedies may be harmful and ineffective.
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Lithium's effect of parathyroid hormone.
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In all patients, discontinuation of aromatic AEDs resulted in resolution of symptoms and in 3 patients who required continued AED therapy, valproic acid was well tolerated.
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Thirty-six patients with AL received, in a three-month period, 51 cycles of combined chemotherapy which included, in all of them, cytosine arabinoside (ARA-C); among them, along with myelosuppression, five experienced fever, infectious complications, gastrointestinal tract symptoms and severe myalgias.
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A 71-year-old man presented with herpes zoster ophthalmicus and ocular involvement.
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In some cases they may cause serious complications.
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Although no coagulation study was done and the Meckel's diverticulum is normally associated with bleeding, the particular intensity of the following hemorrhage may have been favored by metformin.
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Levofloxacin-induced toxic epidermal necrolysis in an elderly patient.
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Possible mechanisms and potential therapies are discussed.
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A 51-year-old man developed type 1 diabetes mellitus following 24 weeks of treatment with recombinant alpha-2b peginterferon plus ribavirin for chronic hepatitis C.
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CONCLUSIONS: This report indicates clindamycin phosphate vaginal cream as the most probable cause of CDIC due to the temporal relationship between the occurrence of diarrhea and clindamycin administration, lack of concomitant medications, and documentation of C. difficile toxin.
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We hypothesize that caffeine toxicity injured the muscle cells, which were fragile due to the potassium depletion induced by the coexisting hyponatremia, to result in unusually severe rhabdomyolysis.
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Neutrophilic dermatoses in two children with idiopathic neutropenia: association with granulocyte colony-stimulating factor (G-CSF) therapy.
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PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.
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After withdrawal of ibopamine and under continuation of all other concomitant medications her body weight continued to decrease during the following few days, her symptoms were alleviated and she was discharge to a nursing home.
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Ciprofloxacin is one drug that has been reported to cause interstitial nephritis.
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In 3 consecutive cases in which a small break in the thin conjunctiva adjacent to the scleral flap was created during trabeculectomy, sodium hyaluronate 2.3% (Healon5) was intraoperatively injected into the bleb.
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Over two-thirds of the patients treated with intravenous cimetidine demonstrated a reduction in gastrointestinal symptom severity, and a statistically significant reduction in the mean severity rating for all patients was observed.
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We discuss the association of immune suppression and melanoma.
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Primary pneumococcal peritonitis complicated by exudative pleural effusion in an adolescent girl.
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Unwanted corticosteroid effects in childhood bone marrow failure, renal failure and brain damage: case report.
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A patient with end stage renal disease secondary to systemic lupus erythematosus (SLE) ultimately required amputation of the four extremities and developed mesenteric ischemia.
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Venography demonstrated a large atrial thrombus in the superior vena cava and right atrium.
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Trimethadione treatment may be a useful tool for chemical dissolution of pancreatic stones.
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This is the first case where epoprostenol has been successfully reinstituted.
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Ileal biopsy revealed an erosive enteritis with mucosal inflammatory infiltrate and disruption of the surface epithelium.
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The scant information available in the published literature regarding this phenomenon is reviewed with regard to 5-fluorouracil.
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The antibiotic and cyclosporine were stopped and the child was managed with furosemide, nifedipine and steroids.
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However, the pathologic diagnosis was meningioma.
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An unusual complication of chemotherapy: an abscess in the pterygopalatine fossa.
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Within 10 days after cystoscopy causing urosepsis this patient developed persistant neckpain as initial symptom of vertebral osteomyelitis.
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Incidence of myopathy in patients treated with antimalarials.
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A wide variety of adverse central nervous system effects have been reported in association with propafenone; dizziness is the most common.
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Later, both patients evolved to non-Hodgkin's lymphoma (NHL) (diffuse large B-cell lymphoma and peripheral T-cell NHL, respectively).
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However, severe limiting headaches are rarely experienced in this setting and no known therapy has been described for such a serious side effect.
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Histologic examination of the excised specimen showed chronic granulomatous inflammation, and subsequent microbiologic studies cultured an acid- and alcohol-fast bacillus that was later identified as Mycobacterium fortuitum.
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Re-administration of a combination of chemotherapy + Gemtuzumab at relapse in CD33+ AML patient allows to second remission and is feasible without extra toxicity.
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We suspect that similar syndromes reflecting injury to the spinal cord injury may be unrecognized following surgical repair of coarctation.
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Although TPN appears to be beneficial in some patients with cancer, it is expensive and is associated with several significant disadvantages.
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A biopsy specimen showed neutrophilic panniculitis.
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Heparin-associated thrombocytopenia and thrombosis is a severe complication of systemic heparin therapy.
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Three patients with progressive multifocal leukoencephalopathy (PML) treated with highly active antiretroviral therapy (HAART) worsened clinically and radiologically.
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Nasopharyngeal cancer is not common in the Caucasian population; however, there is a much higher incidence in Asian patients.
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RESULTS: Visceral leishmaniasis was established by bone marrow aspiration, and although there was no histological confirmation, according to HLH-2004 criteria, a secondary macrophagic activation syndrome was established.
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Despite maximal anti-glaucomatous medication, IOP still could not be controlled.
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The combination therapy resulted in abrupt alleviation of psychotic symptoms in one of the cases, and maintenance with low-dose clozapine allowed for long-term efficacy.
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Vapreotide, a new somatostatin analogue in the palliative management of obstructive ileus in advanced cancer.
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On comparing the amino acid sequence of the index patient with the consensus sequence, five mutations were found at pre-S1, five at pre-S2 and twenty-three mutations at the S region.
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CIDP may occur early or late during the treatment course with TNF-alpha antagonists.
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The patient had been treated successfully in the hospital with intravenous methylprednisolone.
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We report a 71-year male with castration-resistant metastatic prostate cancer who was treated with weekly docetaxel for 12 weeks and developed significant eye irritation and dryness during treatment.
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We evaluated a patient who developed a psychotic disorder after 4 months of isoniazid prophylaxis for a positive tuberculosis tine test.
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CASE DESCRIPTION: A patient with congenital afibrinogenemia presented with recurrent hemiparesis.
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The attributable mortality rate is 15%, with the most significant factor being treatment delay (mean time from presentation to initiation of treatment, 6.74 weeks).
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ACE inhibitor fetopathy is characterized by fetal hypotension, anuria-oligohydramnios, growth restriction, pulmonary hypoplasia, renal tubular dysplasia, and hypocalvaria.
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The use of botulinum toxin in the treatment of a parotid duct injury during Mohs surgery and review of management options.
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Serum antinuclear antibodies were positive (1:640 speckled pattern), and anti-double-stranded DNA was positive (1:80); moreover, positivity of anti-extractable nuclear antigen was observed.
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Animal models showing paradoxical or opposing responses to serotonin-enhancing agents may apply to human sexual functioning as well.
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SASP is known to be mainly metabolized by N-acetyltransferase 2 (NAT2), and acetylation phenotypes (rapid, intermediate and slow acetylator) correlate with NAT2* genotypes.
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In both cases, CSF pleocytosis was limited to 20 or 60 cells with variable protein and sugar values.
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Investigations showed abnormal liver function tests, pancytopenia and elevated serum levels of aflatoxins.
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Haemolytic-uraemic syndrome complicating long-term mitomycin C and 5-fluorouracil therapy for gastric carcinoma.
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A 35-year-old nephrotic man developed acute renal failure with serum creatinine to 1543 micromol/l after a month of therapy with enalapril.
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Soon after introduction of insulin therapy, she developed severe anasarca, including marked peripheral oedema, ascites and pleural effusion.
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The possible mechanisms for this severe elevation of the calcium level are discussed.
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She was receiving phenytoin sodium 300 mg/day; carbamazepine 200 mg four times daily had been discontinued four days before admission because of leukopenia.
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From September 5 to November 4, 1991, four consecutive patients placed on centrifugal ventricular assist devices (VADs) for cardiac failure were supported with Biomedicus pumps coated with the Carmeda bioactive surface.
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Focal renal cortical necrosis associated with zomepirac.
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A patient developed transient, acute myopia while on isotretinoin (Accutane) therapy for acne.
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A review of the literature was carried out with special reference to the significance of clinical myopathy with a negative biopsy.
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It has been observed after a variety of lesions affecting the posterior nerve roots, the spinal ganglia and the peripheral nerves.
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RESULTS: The patient retained excellent visual acuity and the choroidal hemorrhage resolved completely within two months.
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Sagittal sinus thrombosis associated with transient free protein S deficiency after L-asparaginase treatment: case report and review of the literature.
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He had experienced subarachnoid hemorrhage (SAH) from a left vertebral dissecting aneurysm, and had subsequently received a ventriculoperitoneal shunt against post-SAH hydrocephalus.
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Histological improvement with lamivudine therapy for de novo hepatitis B occurring in an anti-HBs-positive child after bone marrow transplantation.
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Progressive anemia following combination therapy with interferon-alpha and interleukin-2 in a patient with metastatic renal cell carcinoma.
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Allergic contact angioedema to benzoyl peroxide.
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