ENTITY
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DEFINITION
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C0016263
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Microfluorometry, Flow|Cytofluorometry, Flow|Cytometry, Flow|Flow Cytometries|Flow cytometry (procedure)|Flow cytometry|Microfluorimetry, Flow|Flow Microfluorometry|Flow Microfluorimetry|Flow Cytometry|FLOW CYTOMETRY|flow cytometry|flow cytofluorometry|Microfluorometries, Flow|Flow Cytofluorometries|Flow cytometry, NOS|Flow cytometry (FC)|Flow cytometry technique (qualifier value)|Flow Cytofluorometry|flow cytophotometry|Cytometries, Flow|Flow cytometry technique|cytometry flow|Flow Microfluorometries|Cytofluorometries, Flow
Flow Cytometry
C0027229
A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
Formylmethionylleucylphenylalanine|N-Formylmethionine Leucyl-Phenylalanine|N Formyl Methionyl Leucyl Phenylalanine|Formylmet-Leu-Phe|fMLP (formyl-met-leu-phe)|Formylmethionyl-Leucyl-Phenylalanine|L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)-|N Formylmethionine Leucyl Phenylalanine|Formylmet Leu Phe|N-Formyl-Methionyl-Leucyl-Phenylalanine|Formylmethionyl Leucyl Phenylalanine|Leucyl-Phenylalanine, N-Formylmethionine
N-Formylmethionine Leucyl-Phenylalanine
C0031308
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Phagocytosis, NOS|Phagocytosis, function (observable entity)|phagocytose|Phagocytoses|phagocytoses|Phagocytosis, function|phagocytosis|Phagocytosis
Phagocytosis
C0007009
A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.
Product containing carbon (medicinal product)|Carbon-containing product|Carbon 12|Carbon, NOS|carbons|Carbon|carbon|Carbon (substance)|Carbon-12|Elemental Carbon|C element
Carbon
C0003339
Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.
surface antigens|Immunologic Surface Markers|Immunological Surface Markers|Surface Markers, Immunological|surface antigen|Surface Markers, Immunologic|Cell Surface Antigens|Antigens, Surface|cell surface antigens|Cell Surface Antigen|Antigens, Cell Surface|antigen surface|cell surface antigen|Cell surface antigens|Surface Antigens|Antigen, Surface|Antigen, Cell Surface|Markers, Immunologic Surface|Surface Antigen, Cell|Surface Antigens, Cell|Surface Antigen|Markers, Immunological Surface
Surface Antigens
C0076352
null
null
tetronic 701
C0076352
null
null
tetronic 701
C0076352
null
null
tetronic 701
C0076352
null
null
tetronic 701
C1266909
null
Entire bones|Entire bony skeleton|Entire osseous part of the skeletal system|Entire skeletal bones|Entire bone|Entire bony skeleton (body structure)|Entire pars ossea systematis skeletalis|Entire bone (system)
Entire bony skeleton
C0018799
Pathological conditions involving the HEART including its structural and functional abnormalities.
Morbus cordis|cardiac disease|HEART DISEASES|Cardiopathy, NOS|syndrome heart disease|disorder heart|disease hearts|cardiac diseases|Morbus cordis NOS|Disorder of heart|heart diseases|Heart--Diseases|heart disorders|Diseases of the heart|HEART DISEASE, NOS|Cardiac diseases|Heart disease, NOS|cardiopathy|diseases disorders heart|diseases of the heart|Morbus cordis, NOS|cardiac disorders|Heart disease, unspecified|Heart Disorder|Cardiac Disorders|Heart disease NOS|Cardiac Disorder|Heart disease|cardiac disorder|cardiopathies|HEART DISEASES: GENERAL TERMS|morbus cordis|Cardiac disorder|Cardiac Diseases|Heart trouble|Heart Disease|Diseases and Syndromes of Heart|Cardiac Disease|disease cardiac|Heart Disorders|Heart Diseases|heart disease|Cardiopathy|heart disease disorder|Heart disease (disorder)|disease disorders heart|heart disorder|DISORDER CARDIAC (NOS)|HEART DISORDER|Disease or syndrome of heart
Heart Diseases
C0018808
Heart sounds caused by vibrations resulting from the flow of blood through the heart. Heart murmurs can be examined by HEART AUSCULTATION, and analyzed by their intensity (6 grades), duration, timing (systolic, diastolic, or continuous), location, transmission, and quality (musical, vibratory, blowing, etc).
Heart Murmur|Heart murmur, NOS|cardiac murmur|Cardiac murmur|Murmurs, Heart|Cardiac murmur, NOS|murmurs|Heart murmur (observable entity)|Cardiac Murmurs|Observation of heart murmur|Murmur, Cardiac|Murmur (finding)|HEART MURMUR|heart murmurs|Murmur, NOS|heart murmur|murmuring|Heart murmur (finding)|Finding of heart murmur|Murmur, Heart|Heart murmur|Cardiac murmurs|Cardiac Murmur|Murmur|MURMUR|cardiac murmurs|Heart murmur NOS|Murmurs, Cardiac|murmur|Heart murmurs|heart murmuring|Heart Murmurs
Heart murmur
C0180112
A device designed to control or regulate the operation of another device.
controller|Controller Device|Controller|controllers
Controllers
C0241863
null
DIABETIC|diabetics
diabetic
C0333279
null
massive blood loss|Massive hemorrhage|massive hemorrhage|blood loss massive|Massive haemorrhage|Massive bleeding|massive bleeding|Massive hemorrhage (morphologic abnormality)|Massive blood loss
Massive hemorrhage
C0037303
The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.
Bone of cranium|Bone structure of cranium|Set of bones of cranium|Bone structure of cranium (body structure)|Bones of Cranium and Face|BONE, SKULL|Cranium|Bones of cranium|skull|Skull, NOS|Skull|cranium|Skulls|cranial|skulling|SKULL|Cranial bone|cranium bone|skulls|skull bone|Cranial
Bone structure of cranium
C0040405
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Computerized tomography|cat scans|CAT - Computerised axial tomography|computed tomography|Computed Tomography, X Ray|Computerized Tomography, X-Ray|x-ray computed tomography|CAT Scan, X Ray|Tomography, X-Ray Computer Assisted|CT scan, without IV contrast|cat procedure scan|Computed Tomography, Xray|Computed tomography|tomography|CT Scan, X-Ray|X-Ray CAT Scans|Scan, X-Ray CT|scan cat|Computerized Tomography, X Ray|Computerised transaxial tomography|Xray Computed Tomography|X-Ray Computer Assisted Tomography|Computerized tomograph scan|ctt|X Ray Computer Assisted Tomography|computed x-ray tomography|computerized axial tomography|catting|X Ray Tomography, Computed|tomography, computed|Tomography, Computed X-Ray|computed tomography x rays|EMI scan|CAT Scans|scan ct|Computerised tomograph scan|Scan, X-Ray CAT|Computed axial tomography|cat scanning|computerised tomography|Computed Tomography, X-Ray|X-Ray Computed Tomography|CT SCAN|CT Scans|CT scan|Transmission Computed Tomography|Computerized axial tomography (procedure)|tomodensitometry|Computerized Tomography|cat scan procedure|computed axial tomography|Tomography, X Ray Computer Assisted|CT Scan, X Ray|cats scan|CT - Computerised tomography|CT scans|CAT Scan|Computerized axial tomography|C.A.T. scan NOS|Tomographies, Computed X-Ray|Computed X-Ray Tomography|c.a.t. scan|X Ray Computerized Tomography|Tomography, X-Ray Computerized|Computed Tomography, Transmission|Computed Tomography|ct scanning|CAT - Computerized axial tomography|CT - Computerized tomography|Scans, X-Ray CT|CAT scan, NOS|Tomography, X Ray Computerized|computer assisted tomography|X-Ray Computerized Tomography|Tomodensitometry|CT X Rays|X-Ray CT Scans|Computerized Axial Tomography|Computed X Ray Tomography|X-Ray CT Scan|CT X Ray|X-Ray Tomography, Computed|Tomography, X-Ray Computed|Tomography, Xray Computed|CT scan without IV contrast|COMPUTERIZED TOMOGRAPHY|Computerized transaxial tomography|computing tomography|CAT|X-Ray CAT Scan|emi scan|computerized tomography|X Rays, CT|Tomography, Transmission Computed|Computerized transaxial tomography, without IV contrast|Computerized axial tomography, NOS|Computerised axial tomography|assisted computer tomography|Scans, X-Ray CAT|CT|Computerised tomography|ctt scan|Computerized transaxial tomography, NOS|Computerized transaxial tomography without IV contrast|CAT scan|CT Scans, X-Ray|CAT Scan, X-Ray|Tomography, X Ray Computed|c a t scan|Computerized tomography without IV contrast|CAT Scans, X-Ray|X Ray, CT
X-Ray Computed Tomography
C0008679
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
chronic disorders|Chronic disorder|chronic disease/disorder|Chronic Disease|Chronic Illness|chronic illnesses|chronic diseases|Chronic disease|chronic disease|Diseases, Chronic|Illness, Chronic|Chronic disease, NOS|Chronic disease (disorder)|Illnesses, Chronic|chronic disorder|Disease, Chronic|Chronic Diseases|Chronic Illnesses|chronic illness|Chronic diseases
Chronic disease
C1283241
null
Computer equipment (physical object)
Computer equipment
C0162563
Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias.
Catheter Ablation|ablation cardiac|Cardiac Ablation|Catheter ablation|Ablation, Catheter|ablations catheter|cardiac ablation|catheter ablation|ablation catheter|ablations cardiac
Cardiac ablation
C1512721
A non-invasive form of electroanalgesia, based on TENS, that uses the principle of amplitude modulation to decrease the discomfort of stimulating deeper tissues when using transcutaneously applied electrical current. It is often used in physiotherapy and rehabilitation settings. (White, Li, and Chiu)
ICT|Inferential Current Treatment
Inferential Current Treatment
C0001811
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Aging|Aging (finding)|ageing|AGING|aging|Ageing
Aging
C0013144
The sensation of struggling to remain awake.
Mental status, drowsy|Somnolent|Drowsy|somnolence|drowsy|SLEEPY|somnolent|Drowsiness, function (observable entity)|DROWSY|Drowsy (finding)|SOMNOLENT|DROWSINESS|Drowsiness|Drowsiness, function|Sleepy|drowsiness|Sleepiness|sleepiness|Somnolence|sleepy|Somnolence (sleepiness)
Drowsiness
C0278140
null
severe pain|Severe pain (finding)|Severe pain|pains severe|pain severe
Severe pain
C0003087
The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.
ankle joints|ankle joint|Syndesmosis, Ankle|Ankle joint structure (body structure)|Talocrural Joints|Tarsus|Articulatio talocruralis|Joint, Ankle|Joint of ankle|Joints, Ankle|hock joint|Hock joint|Ankle Syndesmoses|Ankle joint, NOS|Ankle Joint|talocrural joint|ankles joints|Ankle|Ankle Joints|Hock joint, NOS|Talocrural Joint|ANKLE JOINT|Ankle joint|Tarsal joint|Talocrural joint|Ankle Syndesmosis|Ankle joint structure
Ankle joint structure
C0871334
null
seminary
seminaries
C0001625
A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.
bilateral adrenal gland|both adrenal glands|ADRENAL GLAND|Glandula suprarenalis|Adrenal structure (body structure)|Adrenal structure|Adrenal|Glands, Adrenal|Adrenals|Gland, Adrenal|Adrenal Gland|ADRENAL GLANDS|Adrenal glands|Suprarenal gland|Adrenal gland, NOS|adrenal glands|adrenal gland|Set of adrenal glands|Adrenal gland|Adrenal Glands|Bilateral adrenal glands|adrenals glands|GLAND, ADRENAL|suprarenal gland
Adrenal Glands
C0020541
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
portal hypertension|HYPERTENSION PORTAL|Portal Hypertension|Hypertensions, Portal|PHT - Portal hypertension|Hypertension, Portal|PORTAL HYPERTENSION|Portal hypertension syndrome|Portal hypertension (disorder)|Portal hypertension|Portal Hypertensions|HYPERTENSION, PORTAL|hypertension portal
Portal Hypertension
C1151057
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O. [EC:1.9.3.1]
cytochrome-c oxidase activity|cytochrome c oxidase activity|ferrocytochrome-c:oxygen oxidoreductase|NADH cytochrome c oxidase
cytochrome c oxidase activity
C0012403
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Dimethylsulfoxide|Methylsulfinylmethane|dimethyl sulphoxide|Sulfinylbis(methane)|dimethylsulphoxide|Dimethylsulphinyl|Dimethyl Sulfoxide|Sulfinylbismethane|Dimethyl sulfoxide (substance)|Dimethyl sulfur oxide|dmso|DMSO - Dimethylsulfoxide|DMSO|Sulphoxide, Dimethyl|Dimetil sulfóxido|(DMSO)|Diméthylsulfoxyde|Dimethyli sulfoxidum|Dimethyl sulphoxide|Sulfoxide, Dimethyl|Dimethyl sulfoxide-containing product|S(O)Me2|dimethyl sulfoxide|DIMETHYL SULFOXIDE|Dimethyl Sulphoxide|Methane, sulfinylbis-|Dimethylsulfoxid|Dimethyl sulfoxide|Product containing dimethyl sulfoxide (medicinal product)|dimethylsulfoxide|Dimethylsulphoxide
dimethyl sulfoxide
C0332461
null
Patch, NOS|Plaque (morphologic abnormality)|Plaque|Plaque, NOS|Patch|plaque|plaque lesion
Plaque (lesion)
C0002940
Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics.
Aneurysm, NOS|Aneurysms|Aneurysmal dilatation, NOS|Dilatation|ANEURYSMS|Aneurysm (disorder)|Aneurysm|aneurysms|Aneurysm of unspecified site|Wider than typical opening or gap|Aneurysm (morphologic abnormality)|aneurysm|aneurysmal dilatation|Aneurysmal dilatation|ANEURYSM
Aneurysm
C0003515
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
Aortography|Contrast aortogram|Aortographies|contrast aortogram|Arteriography of aorta|Aortography (procedure)|Arteriography of aorta and aortic arch|aortography|Aortography, NOS|aortogram
Aortography
C0734810
null
Intestinal submucosa|Submucosa of intestine
Intestinal submucosa
C0332835
Organs, tissues, or cells taken from the body for grafting into another area of the same body or into another individual.
Transplants|Transplant, NOS|graft|transplanting|transplanted organ|Transplant (body structure)|Grafts|transplanted tissue or organ|transplant|transplanted|grafts|Transplanted tissue|grafting|Graft, NOS|GRAFT|Transplanted organ|Transplant|TRANSPLANTS|transplants|Graft
Transplanted tissue
C0043240
Restoration of integrity to traumatized tissue.
Tissue Repair|tissue repair|repair|Wound Healings|Repair following injury|Healing|Wound Repair|Healing, Wound|Tissue repair, NOS|repair tissue|wound healing|Wound healing, NOS|Healings, Wound|Healing following injury, NOS|Repair|Finding of wound healing|wound heal|repairs|Finding of wound healing (finding)|healing wounds|Structure resulting from tissue repair process (morphologic abnormality)|healing|healings|heal|Healing following injury|repairing|Tissue repair|heals|Wound Healing|Repair following injury, NOS|heals wounds|repairing tissues|Observation of wound healing|Wound healing|healed wounds|Structure resulting from tissue repair process
Wound Healing
C0227268
Loose, filamentous areolar connective tissue between the muscularis mucosa and the muscular coat of the small intestine. It contains blood vessels, lymphatics, and nerves. The duodenal submucosa contains mucus-secreting Brunner's glands.
Small intestinal submucosa|Small intestine submucosa|Tela submucosa (Intestinum tenue)|Tela submucosa intestini tenuis|Submucosa of small intestine|Small Intestinal Submucosa|Small intestine submucosa (body structure)
Small intestine submucosa
C0337143
null
Scaffold, device (physical object)|scaffolds|Scaffold, device|Scaffold|scaffolding|scaffold
Scaffold
C0014872
A plastic operation on the esophagus. (Dorland, 28th ed)
Esophagoplasties|Oesophagoplasty|ESOPHAGUS: SURGICAL REPAIRS, CLOSURES AND RECONSTRUCTIONS|Repair of esophagus|Esophagoplasty|Repair of esophagus (procedure)|Oesophagoplasty, NOS|Esophagoplasty, NOS|Repair of esophagus, NOS|esophagoplasty|esophageal repair|Repair of oesophagus|Repair of oesophagus, NOS|oesophageal repair
Esophagoplasty
C0205054
Refers to the liver.
Portal|portal|Hepar|Hepatic|Portal (qualifier value)|hepatic|Hepatico-
Hepatic
C0920569
null
liver ischemia
hepatic ischemia
C0678544
null
waves|wave|waving
wave - physical agent
C0039985
An x-ray examination of the chest.
Chest Radiography|thoracic x-ray|Radiography of chest, NOS|Radiologic examination of chest, NOS|chest x rays|chest radiography|CXR - Chest X-ray|Plain chest X-ray|Chest exclusion X-ray|Radiography of chest|chest x-ray|Chest x-ray|X-ray of chest NOS|thorax x-ray|thoracic x rays|Radiologic examination of chest|Chest X-ray|Plain chest X-ray (procedure)|Chest x-ray, NOS|chest X ray|chest x ray|cxr|thoracic radiography|Chest--Radiography
Plain chest X-ray
C0150411
Measures the acidity (pH) and the levels of oxygen, carbon dioxide, and bicarbonate in the blood.
arterial blood gases|arterial blood gase|Analysis of arterial blood gases and pH|ABG|blood gas arterial|Analysis of arterial blood gases and pH (procedure)|analysis arterial blood gas|arterial blood gas analysis|Blood gases, arterial measurement (procedure)|Arterial blood gases|Arterial blood gas analysis|ABGs measurement|Analysis of arterial blood gas (oxygen saturation, pO2, pCO2, CO2, pH); rest only|Measurement of systemic arterial blood gases|Gases, arterial measurement|Blood Gas Measurement|Blood Gas Analysis|ABG - Arterial blood gas analysis|Arterial Blood Gas Measurement|arterial blood gas|Blood gases, arterial measurement
Analysis of arterial blood gases and pH
C0199470
A method to mechanically assist or replace spontaneous breathing in patients by use of a powered device that forces oxygenated air into the lungs.
Ventilation, Mechanical|MECHANICAL VENTILATION|Respiratory assist, mechanical|Mechanically assisted breathing|mechanical ventilation|mechanical respiratory assist|Mechanical Ventilation|Mechanical ventilation|Mechanical ventilation, NOS|Ventilations, Mechanical|Mechanical ventilation NOS|Mechanically assisted ventilation|Mechanical Ventilations
Mechanical ventilation
C0225369
Polymorphic cells that form cartilage.
chondrocyte|Cartilage cell|Chondrocyte (substance)|Chondrocytes|Chondrocyte (cell)|Cartilage cell, NOS|Chondrocyte|cartilage cell|chondrocytes
Chondrocyte
C1306577
null
Death|Patient died|dies patient|Patient died (finding)|DEATHS|O/E - dead|O/E - dead - condition fatal|patient died|On examination - dead|On examination - dead (finding)|Death, NOS
Death (finding)
C0023185
Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.
learned|learn|Learning|Learning, NOS|learning|Learning, function|Learning, function (observable entity)
Learning
C0072402
A group of enzymes that catalyzes the phosphorylation of serine or threonine residues in proteins, with ATP or other nucleotides as phosphate donors.
Kinase, Protein-Threonine|Protein Serine Kinase|Kinase, Protein-Serine-Threonine|Protein Serine Threonine Kinase|Serine Threonine Protein Kinases|serine-threonine kinase|Kinase, Protein-Serine|Serine Kinase|Kinases, Serine-Threonine|Kinases, Protein-Serine-Threonine|Serine(threonine)protein kinase|Kinase, Serine|STK|Protein-Serine-Threonine Kinase|Kinase, Threonine|Protein Threonine Kinase|Serine-Threonine Protein Kinases|EC 2.7.11.1|Protein-Serine Kinase|Protein-Serine-Threonine Kinases|Serine-Threonine Kinases|Kinase, Serine-Threonine|Threonine Kinase|serine threonine protein kinase|EC 2.7.11|Serine Threonine Kinases|Serine-Threonine Kinase|Serine Threonine Kinase|serine threonine kinase|Serine/Threonine-Protein Kinase|Protein Serine Threonine Kinases|serine-threonine kinases|Protein-Threonine Kinase|Serine/Threonine Protein Kinase|Serine-Threonine Protein Kinase|Kinases, Serine-Threonine Protein|Protein Kinases, Serine-Threonine
Protein-Serine-Threonine Kinases
C0009093
null
Morpholinium, 4-(2-((cyclohexylcarbonimidoyl)amino)ethyl)-4-methyl-, salt with 4-methylbenzenesulfonic acid (1:1)|CME Carbodiimide|Carbodiimide, CME|4-(2-((Cyclohexylimidocarbonyl)amino)ethyl)-4-methylmorpholinium|CMEC
CME-Carbodiimide
C1325651
The region of a mitochondrion to which the DNA is confined. [GOC:jl]
mitochondrial nucleoid
Mitochondrial nucleoid
C1180347
null
Protein complex|complex protein|protein complex
Protein complex
C0243041
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
Molecular Chaperone|Chaperone|molecular chaperone|Molecular chaperones|Chaperone, Molecular|Chaperones, Molecular
Molecular Chaperones
C0678591
A thermodynamic term used to describe the energy that may be extracted from a system at constant temperature and pressure. In biological systems the most important relationship is: G = RTln(Keq), where Keq is an equilibrium constant.
free energy
Free Energy
C0544157
null
Deinococcus radiidurans|Deinococcus radiodurans|Micrococcus radiodurans|Deinococcus radiodurans (organism)
Deinococcus radiodurans
C1148672
Interacting selectively and non-covalently with any nucleic acid. [GOC:jl]
nucleic acid binding
Nucleic Acid Binding
C0035701
The most abundant form of RNA. Together with proteins, it forms the ribosomes, playing a structural role and also a role in ribosomal binding of mRNA and tRNAs. Individual chains are conventionally designated by their sedimentation coefficients. In eukaryotes, four large chains exist, synthesized in the nucleolus and constituting about 50% of the ribosome. (Dorland, 28th ed)
ribosomal RNA|ribosomal RNA (rRNA)|RNA, Ribosomal|rrna|Ribosomal ribonucleic acid (substance)|ribosomal rna|Ribosomal RNA|RNA, ribosomal (rRNA)|Ribosomal ribonucleic acid|rRNA|RRNA
Ribosomal RNA
C0077157
null
null
trimetaphosphoric acid
C0077157
null
null
trimetaphosphoric acid
C0015914
The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.
syngamy|Fertilization, function (observable entity)|Fecundation, NOS|Fertilization, function|Fertilization, NOS|Fertilisation|fecundation|fertilization|Fertilizations|fertilizations|impregnation|fertilisation|Fecundation|Fertilization
Fertilization
C0055127
null
null
Cerumol
C0087157
null
village health worker|Workers, Village Health|Health Worker, Village|village health workers|Health Workers, Village|Worker, Village Health|Village Health Worker
Village Health Workers
C0087157
null
village health worker|Workers, Village Health|Health Worker, Village|village health workers|Health Workers, Village|Worker, Village Health|Village Health Worker
Village Health Workers
C0872078
Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.
presenilins|presenilin|Presenilins|Presenilin
Presenilins
C1235660
null
notch|Notch|notching
Notch
C0162768
A protein made from a fusion gene, which is created by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene that makes the BCR-ABL fusion protein. Fusion genes and proteins can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.
Fusion protein (substance)|chimeric protein|fusion protein|Product containing fusion protein (product)|Chimeric Protein|chimeric proteins|Fusion protein-containing product|Chimera Protein|Fusion Protein
Fusion protein
C0521324
null
Skeletal|skeletal|SKELETAL
Skeletal
C0097550
Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.
Dystroglycan|Cranin
Dystroglycans
C0039848
The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
Thiamin pyrophosphate|Cocarboxylase|cocarboxylase|tpp|Pyrophosphoric Ester of Thiamine|Thiamine pyrophosphate|thiamine pyrophosphate (TPP)|thiamine pyrophosphate|Thiamine Diphosphate|Thiamine diphosphate|TPP|Thiamine pyrophosphate (substance)|COCARBOXYLASE|Pyrophosphate, Thiamine|Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride, P,P'-dioxide|Thiamine Pyrophosphate
thiamine pyrophosphate
C0034320
Inorganic salts of phosphoric acid that contain two phosphate groups.
Pyrophosphate|diphosphate|pyrophosphate|Diphosphates|Pyrophosphates|DIPHOSPHATES|Pyrophosphate (substance)
Diphosphates
C0378310
CCAAT/enhancer binding protein alpha (358 aa, ~38 kD) is encoded by the human CEBPA gene. This nuclear protein is a DNA-binding bZIP transcription factor that, as a homodimer, recognizes common motifs in both the promoter (CCAAT sequence) and enhancer (core homology sequence) regions of genes.
C/EBP Alpha|CCAAT/Enhancer Binding Protein Alpha|CEBP|CCAAT-Enhancer-Binding Protein-alpha|C-EBP alpha|CEBPA|CEBP Alpha|C EBPalpha|C EBP alpha|CCAAT Enhancer Binding Protein alpha|C-EBPalpha
CCAAT/Enhancer Binding Protein Alpha
C0002520
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
amino acid|Amino acids NOS|Amino acids|AA - Amino acid|aa|aminoacids|amino acids|Amino Acids|AMINO ACIDS|Amino Acid|AMINO ACID PREPARATION|Amino acid, NOS|Acids, Amino|Product containing amino acid (product)|Amino acid-containing product|Amino acid|Amino acid (substance)|aminoacid
Amino Acids
C1148926
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction. [EC:3.6.1.3, GOC:jl]
ATPase activity|adenosine triphosphatase activity|ATP hydrolase activity|adenosine 5'-triphosphatase activity|ATP phosphohydrolase activity|adenosinetriphosphatase activity|ATP monophosphatase activity
adenosinetriphosphatase activity
C0597361
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. [GOC:mah, ISBN:0716731363]
RME|Receptor-Mediated Endocytosis|receptor-mediated endocytosis|receptor mediated endocytosis
Receptor Mediated Endocytosis
C1336344
Stage IVA includes: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4a, N2, M0); T4a: Supraglottis: Moderately advanced local disease. Tumor invades through the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus). Glottis: Moderately advanced local disease. Tumor invades through the outer cortex of the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). Subglottis: Moderately advanced local disease. Tumor invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). N0: No regional lymph node metastasis. N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension. N2: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)
Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Laryngeal Verrucous Carcinoma|Stage IVA Laryngeal Verrucous Carcinoma AJCC v7|Stage IVA Larynx Verrucous Carcinoma|Stage IVA Verrucous Carcinoma of Larynx|Stage IVA Laryngeal Throat Verrucous Cancer
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
C1336344
Stage IVA includes: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4a, N2, M0); T4a: Supraglottis: Moderately advanced local disease. Tumor invades through the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus). Glottis: Moderately advanced local disease. Tumor invades through the outer cortex of the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). Subglottis: Moderately advanced local disease. Tumor invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, or esophagus). N0: No regional lymph node metastasis. N1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension. N2: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension. M0: No distant metastasis. (AJCC 7th ed.)
Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Laryngeal Verrucous Carcinoma|Stage IVA Laryngeal Verrucous Carcinoma AJCC v7|Stage IVA Larynx Verrucous Carcinoma|Stage IVA Verrucous Carcinoma of Larynx|Stage IVA Laryngeal Throat Verrucous Cancer
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
C0038613
An electron transport chain complex that catalyzes the transfer of electrons from SUCCINATE to CYTOCHROME C. It includes ELECTRON TRANSPORT COMPLEX II and ELECTRON TRANSPORT COMPLEX III.
Succinate cytochrome C reductase|Succinate cytochrome C reductase (substance)|succinate cytochrome C oxidoreductase|Succinate Cytochrome c Reductase
Succinate Cytochrome c Oxidoreductase
C0220918
null
Succinate|succinate
succinate
C0012124
A carbodiimide that is used as a chemical intermediate and coupling agent in peptide synthesis. (From Hawley's Condensed Chemical Dictionary, 12th ed)
Cyclohexanamine, N,N'-methanetetraylbis-|DCCD
Dicyclohexylcarbodiimide
C0001475
The catalytic sector of proton-translocating ATPase complexes. It contains five subunits named alpha, beta, gamma, delta and eta.
F 1 ATPase|Adenosinetriphosphatase F1|Proton-Translocating ATPase, F1 Sector|F1-ATPase|F1 ATPase|Proton Translocating ATPase, F1 Sector|F-1-ATPase|ATPase, F1
F1-ATPase
C0010656
A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
caspase|Cysteine-aspartic Protease|cysteine endopeptidase|Peptidase Family C14|Cysteine-Dependent Aspartate-Directed Protease|ICE-like protease|Caspases|ICE-like proteases|Caspase|Cell-Death Protease|cystein protease|cystein proteinase
caspase
C0010656
A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
caspase|Cysteine-aspartic Protease|cysteine endopeptidase|Peptidase Family C14|Cysteine-Dependent Aspartate-Directed Protease|ICE-like protease|Caspases|ICE-like proteases|Caspase|Cell-Death Protease|cystein protease|cystein proteinase
caspase
C0255567
Vasodilator-stimulated phosphoprotein (380 aa, ~40 kDa) is encoded by the human VASP gene. This protein is involved in both cell motility and cell adhesion.
VASP|vasodilator-stimulated phosphoprotein|Vasodilator-Stimulated Phosphoprotein
vasodilator-stimulated phosphoprotein
C0887869
The binding of a cell to the extracellular matrix via adhesion molecules. [GOC:hb]
cell-matrix adhesion|Cell-Matrix Junctions|Cell-Matrix Adhesion Process|Junctions, Cell-Matrix|Cell-Matrix Adhesions|Cell-Matrix Junction|Cell Attachment|cell-matrix junction|Adhesions, Cell-Matrix|Cell Matrix Adhesions|Cell-matrix adhesions|cell-substrate junction|Junction, Cell-Matrix|Cell Matrix Junctions
Cell-Matrix Junction
C0037663
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Pituitary Growth Hormone|Growth hormone preparation|pituitary growth hormone|Somatotropin preparation|Growth Hormone|somatotropic hormone|Somatotropin-containing product|somatotrophin|growth hormones|Growth Hormone, Pituitary|somatotropin|STH|GH|Product containing somatotropin (medicinal product)|Somatotropin|growth hormone|Somatotropin (substance)|SOMATOTROPIN
Growth Hormone
C0035139
Restoration of an organ or other structure to its original site.
Replacement procedure|Reimplantations|Reimplantation (procedure)|Reimplantation - action (qualifier value)|Re-insertion|Replantations|Surgical Replantation|Replantations, Surgical|replacement procedure|replacement|Reinsertion|re-implantation|Replantation|Surgical Replantations|Replantation, Surgical|Replacement|Reimplantation - action|replantation|reinsertion|Replacement procedure (procedure)|procedures replacement|re implantation|Reinsertion, NOS|reimplantation procedure|replacements|Re-implantation|Reimplantation|Reimplantation, NOS|reimplantation
Surgical Replantation
C0243192
Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16)
agonists
agonists
C1512488
A protein similar in structure and evolutionary origin to a protein in another species.
Protein Homolog
Homologous Protein
C0311284
A systemic disease, often associated with arthritis, fever, and weight loss. The cutaneous lesions consist of histiocytes, which are usually confined to the dermis. A large number of patients develop malignant tumors (carcinomas, sarcomas, and lymphomas). --2003
Lipoid dermato-arthritis|HISTIOCYTOMA, GIANT CELL|RETICULOHISTIOCYTOMA, MULTICENTRIC|Multicentric Reticulohistiocytosis|lipoid dermatoarthritis|MRH|Multicentric reticulohistiocytosis|Lipoid dermatoarthritis|Nicolau-Balus syndrome|MR|LIPOID DERMATOARTHRITIS|Lipoid dermatoarthritis (disorder)
Lipoid dermatoarthritis
C0878544
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
Cardiomyopathies|Cardiomyopathy, NOS|Myocardial disease|Cardiomyopathy (disorder)|Myocardium--Diseases|Myocardial Diseases|Disorder of heart muscle|Diseases, Myocardial|myocardiopathy|myocardial diseases|Cardiomyopathy|Myocardial disease (disorder)|Myocardial Disease|Disease, Myocardial|CARDIOMYOPATHY|Disorder of myocardium|Disease of the heart muscle|myocardium disorder|CARDIOMYOPATHIES|heart muscle disease|Myocardiopathies|cardiomyopathies|myocardial disease|Myocardiopathy|cardiomyopathy|Cardiomyopathy NOS|Myocardiopathy, NOS|Myocardial disease, NOS|heart muscle disorder
Cardiomyopathies
C0410174
An autosomal recessive muscular dystrophy caused by mutations in the gene encoding fukutin (FKTN). It is associated with characteristic brain and eye malformations, seizures, and mental retardation.
Fukuyama congenital muscular dystrophy|Cerebromuscular Dystrophy, Fukuyama Type|Fukuyama Congenital Muscular Dystrophy|Muscular Dystrophy, Fukuyama|muscular dystrophy fukuyama|MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE ANOMALIES), TYPE A, 4|Syndrome, Fukuyama|WALKER-WARBURG SYNDROME OR MUSCLE-EYE-BRAIN DISEASE, FKTN-RELATED|Muscular Dystrophy, Congenital, Fukuyama Type|Fukuyama CMD|fukuyama muscular dystrophy|Fukuyama Syndrome|Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 4|Dystrophy, Fukuyama Muscular|Fukuyama Type Congenital Muscular Dystrophy|MDDGA4|Fukuyama muscular dystrophy|Fukuyama congenital muscular dystrophy (disorder)|CMD, Fukuyama|FUKUYAMA CONGENITAL MUSCULAR DYSTROPHY|FCMD|Fukuyama Muscular Dystrophy
Fukuyama Type Congenital Muscular Dystrophy
C1304649
General anatomical term which refers to an elongatyed anatomical structure which may be a cell, e.g. muscle fiber; an organ component, e.g. nerve fiber; or an acellular anatomical structure, e.g. collagen fiber
Fibre|fibers tissue|fiber|fibered|Fiber|fibres|fibre
Tissue fiber
C0004595
A species of gram-positive bacteria that is a common soil and water saprophyte.
Bacillus subtilis (organism)|BACILLUS SUBTILIS|Vibrio subtilis|Bacillus natto|Bacillus uniflagellatus|bacillus subtilis|bacillus globigii|Bacillus subtilis|subtilis bacillus
Bacillus subtilis
C0242692
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
skeletal muscle|Skeletal muscle tissue|Skeletal muscle structure|striated muscles|Muscles, Skeletal|Voluntary Muscles|striated voluntary muscle|Skeletal Muscle|Skeletal Muscles|SKELETAL MUSCLE TISSUE|Muscles, Voluntary|skeletal muscle structure|MUSCLE, SKELETAL|Voluntary Muscle|Skeletal musculature|Textus muscularis striatus (skeletalis)|Skeletal muscle structure (body structure)|Skeletal muscle|Muscle, Skeletal|Muscle, Voluntary|Skeletal muscles, NOS|striated muscle|Skeletal Muscle Tissue
Skeletal muscle structure
C0026850
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.
Myodystrophicas|Muscular dystrophy, NOS|Muscular dystrophy (disorder)|Muscular dystrophy NOS|MD|MD - Muscular dystrophy|Progressive muscular dystrophy|Muscular dystrophy syndrome|muscular dystrophy|Dystrophies, Muscular|Dystrophic muscle disease or syndrome|Muscular dystrophy|muscular dystrophies|Myodystrophy|myodystrophy|Muscular Dystrophies|PMD - Progressive muscular dystrophy|Myodystrophies|Dystrophic Muscle Diseases and Syndromes|Muscular Dystrophy|Myodystrophica|progressive muscular dystrophy|Dystrophy, Muscular
Muscular Dystrophy
C1312042
null
alpha Dystroglycan|alpha-Dystroglycan
alpha-Dystroglycan
C0027869
The synapse between a neuron and a muscle.
junction neuromuscular|Junction, Neuromuscular|Junctions, Neuromuscular|Junctions, Myoneural|NMJ|Neuromuscular junction (cell structure)|Myoneural Junctions|neuromuscular junction|Myoneural junction|Myoneural Junction|Neuromuscular Junctions|Junction, Myoneural|neuromuscular junctions|Neuromuscular junction|myoneural junction
Neuromuscular Junction
C0235394
null
wasting|wasted|WASTING
Wasting
C1519595
The initial RNA molecule produced by transcription.
Transcripts
Transcript
C1333481
A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.
Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor of Bone
Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor of Bone