ENTITY
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DEFINITION
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C1333481
A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.
Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor of Bone
Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor of Bone
C1413594
null
COL8A2 gene|collagen type VIII alpha 2 chain|FECD1|PPCD|PPCD2|COLLAGEN, TYPE VIII, ALPHA-2|COL8A2
COL8A2 gene
C1413594
null
COL8A2 gene|collagen type VIII alpha 2 chain|FECD1|PPCD|PPCD2|COLLAGEN, TYPE VIII, ALPHA-2|COL8A2
COL8A2 gene
C0004610
The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
Bacteremia, NOS|Bacteremia (finding)|bacteria in the blood|BACTEREMIA|bacteremias|Bacteremia|Unspecified bacteremia|bacteraemia|Bacteraemia|Bacteremias|blood poisoning|bacteremia
Bacteremia
C0033809
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
p. aeruginosa|Pseudomonas pyocyanea|Bacterium aeruginosum|PSEUDOMONAS AERUGINOSA|Pyo|p aeruginosa|Pseudomonas polycolor|pseudomonas aeruginosa|pyo|Pseudomonas pyocyaneus|Pseudomonas aeruginosa|Bacillus pyocyaneus|Pseudomonas aeruginosa (organism)|Bacterium pyocyaneum|pseudomona aeruginosa|Micrococcus pyocyaneus|P. aeruginosa|aeruginosa p|aeruginosa pseudomonas|pseudomonas aeruginosa organism|Bacillus aeruginosus
Pseudomonas aeruginosa
C0384228
An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
Tenofovir|(R)-9-(Phosphonomethoxypropyl)adenine|TENOFOVIR|tenofovir|(((1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonic acid|Tenofovir-containing product|9-(2-Phosphonomethoxypropyl)adenine|9-PMPA (tenofovir)|(R)-9-(2-Phosphonomethoxypropyl)adenine|Product containing tenofovir (medicinal product)|PMPA|9-(2-Phosphonylmethoxypropyl)adenine|Tenofovir (substance)
tenofovir
C1332920
A non-neoplastic disorder that affects the cervix. Representative examples include endometriosis and cervicitis.
Cervical Non-Neoplastic Disease
Cervical Non-Neoplastic Disorder
C1332920
A non-neoplastic disorder that affects the cervix. Representative examples include endometriosis and cervicitis.
Cervical Non-Neoplastic Disease
Cervical Non-Neoplastic Disorder
C0012133
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
2 3 dideoxyinosine|dideoxyinosine|2'3' dideoxyinosine|Dideoxyinosine|2,3-Dideoxyinosine|Didanosina|Didanosine EC|2',3' Dideoxyinosine|ddIno|ddi|Didanosine (substance)|9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one|DIDANOSINE|9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one|9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one|Didanosinum|Product containing didanosine (medicinal product)|Inosine, 2',3'-dideoxy-|Didanosine|ddI|9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol|2',3'-Dideoxyinosine|Didanosine-containing product|ddI (Antiviral)|DDI|didanosine
didanosine
C0252643
A sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension.
Product containing bosentan (medicinal product)|bosentanum|p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide|Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-|Bosentan (substance)|4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide|4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide|Bosentan-containing product|bosentán|Bosentan|bosentan|4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide|BOSENTAN
bosentan
C0036421
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
progressive systemic sclerosis|Systemic Scleroderma|Progressive systemic sclerosis|sclerodermas|PSS|SSc, Diffuse Sclerosis|Diffuse Scleroderma|SCLEROSIS, SYSTEMIC|Scleroderma syndrome|Progressive Systemic Sclerosis|Systemic scleroderma|PROGRESSIVE SYSTEMIC SCLEROSIS|Systemic sclerosis (disorder)|systemic sclerosis|scleroderma|Sclerosis, Systemic|Systemic sclerosis|systemic scleroderma|PSS (progressive systemic sclerosis)|Scleroderma, Diffuse|SS - Systemic sclerosis|Diffuse Sclerosis|Systemic Sclerosis|Scleroderma, Systemic
Systemic Scleroderma
C0007876
Extraction of the FETUS by means of abdominal HYSTEROTOMY.
Caesarean section, NOS|ceasarian section|Cesarean section|abdominal delivery|c section|caesarean section|cesarean deliveries|C Section (OB)|Caesarean section|cesarean delivery|caesarian sections|C-section|cesarian section|Cesarean Delivery|c sections|Cesarean section, NOS|Abdominal Delivery|Caesarian section|Cesarean Sections|C-Section|CAESAREAN SECTION|cesarian sections|CS - Cesarean section|CEASARIAN SECTION|Caesarean Sections|C-Sections (OB)|cesarean section|cesarean sections|Cesarean section NOS|Abdominal Deliveries|C section|Cesarean section (procedure)|caesarian section|Caesarean Section|Deliveries, Abdominal|C-Section (OB)|caesarean sections|caesarean delivery|Cesarean Birth|Cesarean Section|Cesarean section of unspecified type|caesarean section (C-section) delivery|Caesarean Birth|Cesarean section and removal of fetus|Delivery, Abdominal|CS - Caesarean section
Cesarean section
C0013423
A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and face. The hands are often spared, however, sustained axial and limb contractions may lead to a state where the body is grossly contorted. Onset is usually in the first or second decade. Familial patterns of inheritance, primarily autosomal dominant with incomplete penetrance, have been identified. (Adams et al., Principles of Neurology, 6th ed, p1078)
Torsion dystonia fragment syndrome|Dystonia deformans progressiva|Torsion dystonia, idiopathic|idiopathic torsion dystonia|Torsion Dystonia, Idiopathic|Primary torsion dystonia|Dystonia, Idiopathic Torsion|Ziehen Oppenheim disease|Torsion Spasm, Progressive|Dystonia, deformans progressiva|Oppenheim-Ziehen Disease|dystonia deformans progressiva|Dystonia lenticularis syndrome|Dystonia Musculorum Deformans|Spasm, Progressive Torsion|Idiopathic Torsion Dystonia|Childhood Torsion Disease|Idiopathic torsion dystonia (disorder)|Bilateral paraspasm syndrome|Torsion Dystonia|dystonia musculorum deformans|Schwalbe disease|Dystonia Deformans Musculorum|Idiopathic Torsion Dystonias|Ziehen-Oppenheim disease|torsion dystonia|Dystonia, musculorum deformans|Genetic torsion dystonia|Torsion dystonia|Dystonia musculorum deformans|Dystonias, Idiopathic Torsion|Progressive Torsion Spasm|Torsion Disease, Childhood|Dystonias, Torsion|Torsion dystonia (disorder)|Dystonia Deformans Progressiva|Torsion Disease of Childhood|Idiopathic torsion dystonia|Oppenheim Ziehen Disease
Dystonia Musculorum Deformans
C1280090
null
Entire limb (body structure)|Entire limb
Entire limb
C0002915
Procedure in which patients are induced into an unconscious state through use of various medications so that they do not feel pain during surgery.
general anaesthetic|ANESTHESIA GENERAL|General anaesthesia|General anesthetic|general anesthetic|General Anesthesia|ga|General anaesthetic|General anesthesia, NOS|General anaesthesia, NOS|general anaesthesia|General anesthesia|General Anesthesias|anaesthetic general|general anesthesia procedure|GA - General anesthetic|Anesthesia, General|General anesthesia (procedure)|General Anesthesia Procedure|Anesthesias, General|GA - General anaesthetic|general anesthesia
General Anesthesia
C0412767
null
induction rapid sequence|rapid sequence induction|Crash induction|Rapid sequence induction (procedure)|Rapid sequence induction|RSI - Rapid sequence induction
Rapid Sequence Induction
C0038792
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Product containing sulindac (medicinal product)|(Z)-5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid|sulindac|cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid|cis-5-fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid|(Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid|SULIN|Sulindac-containing product|Sulindaco|Sulindacum|1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-|Sulindac|Sulindac (substance)|SULINDAC|cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid
sulindac
C0059360
An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine ethylates DNA, resulting in single- and double-stranded DNA breaks and the inhibition of DNA replication. (NCI04)
ENNG|N-ethyl-N'-nitro-N-nitrosoguanidine|ethyl-N'-nitro-N-nitrosoguanidine
ENNG
C0059360
An alkyl nitrosoguanidine with carcinogenic properties. Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine ethylates DNA, resulting in single- and double-stranded DNA breaks and the inhibition of DNA replication. (NCI04)
ENNG|N-ethyl-N'-nitro-N-nitrosoguanidine|ethyl-N'-nitro-N-nitrosoguanidine
ENNG
C0035695
Nuclear nonribosomal RNA larger than about 1000 nucleotides, the mass of which is rapidly synthesized and degraded within the cell nucleus. Some heterogeneous nuclear RNA may be a precursor to mRNA. However, the great bulk of total hnRNA hybridizes with nuclear DNA rather than with mRNA.
heterogeneous nuclear RNA|Heterogeneous Nuclear RNA|Heterogeneous nuclear ribonucleic acid|Nuclear RNA, Heterogeneous|hnRNA|RNA, Heterogeneous Nuclear|Heterogeneous nuclear RNA|hn RNA|Heterogeneous nuclear ribonucleic acid (substance)|RNA, heterogeneous
Heterogeneous Nuclear RNA
C0040649
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
gene transcription|genetic transcription|Transcription|Transcriptional|genes transcription|Transcription, Genetic|Gene Transcription|RNA Expression|Genetic transcription|transcriptions|transcription|Genetic Transcription|Genetic transcription (finding)
Transcription, Genetic
C0052196
null
apo E1|apolipoprotein E-1|apoE1|apo E-1
apolipoprotein E1
C0052196
null
apo E1|apolipoprotein E-1|apoE1|apo E-1
apolipoprotein E1
C0033413
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Region, Promoter|Genetic Promoter Regions|Regions, Promotor|Regions, Promoter|Genetic promotor region|Promotor Regions|Promoter Regions|Promoter Region|Region, Promotor|Promoter Region, Genetic|Promotor Region|Region, Genetic Promoter|Genetic Promoter Region|genetic promoter element|Regions, Genetic Promoter|Genetic promotor region (finding)
Promoter Regions, Genetic
C0032592
A multiribosomal structure representing a linear array of RIBOSOMES held together by messenger RNA; (RNA, MESSENGER); They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Polyribosome (cell structure)|Polysome|polysome|Polyribosome, NOS|polyribosomes|Polyribosomes|polyribosome|Polysomes|Polyribosome
Polyribosomes
C0330209
A class of vascular plants which produce flowers and seeds. They include monocotyledons, dicotyledons, and about 80% of all known plant species.
Plant, Flowering|Asteridae|Vahliale|Angiosperma|Liliatae|Magnoliopsida|Vahliales|Dicotyledons|Angiosperm|Zingiberidae|Magnoliatae|Dicotyledoneae|Caryophyllidae|dicotyledon|Dicotyledon (organism)|Liliopsida|Commelinidae|Liliidae|Dilleniidae|Rosidae|Flowering Plant|Oncothecales|Hamamelididae|Flowering Plants|DICOTYLEDONS|Icacinales|Dicots|Angiosperms|Metteniusale|Metteniusales|Class Magnoliopsida|Hamamelidae|Plants, Flowering|Dicotyledon, NOS|Class Magnoliopsida (organism)|Arecidae|Icacinale|Angiospermae|Dicotyledon|Oncothecale
Magnoliopsida
C0003062
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.
animal kingdom|Animal, NOS|multicellular animals|Kingdom Animalia (organism)|Animals|animalia|EntityClassAnimal|Animalia|Animal|Kingdom Animalia|animal|ANIMAL|animals
Animals
C0038323
Steroids with a hydroxyl group at C-3 and most of the skeleton of cholestane. Additional carbon atoms may be present in the side chain. (IUPAC Steroid Nomenclature, 1987)
sterols|Sterol|sterol|Sterol (substance)|Sterols|Sterol, NOS
Sterols
C0220781
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [GOC:curators, ISBN:0198547684]
Biosynthesis|Synthesis|synthesis|biosynthesis|Anabolism, function|Biogenesis|Biosynthetic|Anabolism, function (observable entity)|anabolism|Anabolism|formation|biosynthetic process|Biosynthetic Process
Anabolism
C0034595
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Radioisotope|RADIOISOTOPE|Isotopes, Radioactive|Radionuclide|radioisotopes|radioactive isotopes|Radioisotope, NOS|Radioactive isotope (substance)|radioactive isotope|Radioactive Isotopes|Radioactive isotope|radionuclide|radionuclides|Radioisotopes|radioisotope|Radionuclides
Radioisotopes
C0039994
A radioactive element of the actinide series of metals. It has an atomic symbol Th, atomic number 90, and atomic weight 232.04. It is used as fuel in nuclear reactors to produce fissionable uranium isotopes. Because of its radioopacity, various thorium compounds are used to facilitate visualization in roentgenography.
Thorium|Thorium, NOS|Th - Thorium|Thorium (substance)|thorium|THORIUM
thorium
C0041928
A radioactive element of the actinide series of metals. It has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
uranium|Uranium (substance)|Uranium|U element|Uranium, Natural|Uranium, NOS|Uranium U-238|URANIUM
uranium
C0337050
Large natural streams of FRESH WATER formed by converging tributaries and which empty into a body of water (lake or ocean).
Flowing stream|Rivers|River (environment)|river|rivers|River|River/ flowing stream
Rivers
C0167220
Bipartite DNA binding protein containing a basic region that directly interacts with DNA, and a leucine zipper that mediates dimerization through contacts with a protein partner.
Basic Leucine Zipper Transcription Factors|bZIP G Box Binding Factors|Transcription Factors, bZIP|GBF bZIP Transcription Factors|bZIP Protein|bZIP Proteins|bZIP G-Box Binding Factors|bZIP Transcription Factors
Basic-Leucine Zipper Transcription Factors
C0026019
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
EM - Electron microscopy|Microscopy, Electron|ELECTRON MICROSCOPY|Electron microscopic study, NOS|electron microscopy|EM|microscopy, electron|Electron microscopy|Electron Microscopy|Electron microscopic study|ELECTRON MICROSCOPY AND MORPHOMETRY|Electron microscopic study (procedure)
Electron Microscopy
C0054490
null
null
calcium-dependent protein kinase
C0242774
A creeping annual plant species of the CUCURBITACEAE family. It has a rough succulent, trailing stem and hairy leaves with three to five pointed lobes.
Cucumis sativus|cucumbers
Cucumis sativus
C0936045
A plant genus of the family CUCURBITACEAE, order Violales, subclass Dilleniidae best known for cucumber (CUCUMIS SATIVUS) and cantaloupe (CUCUMIS MELO). Watermelon is a different genus, CITRULLUS. Bitter melon may refer to MOMORDICA or this genus.
Cucumis, NOS|Cucumber|cucumber|Cucumis|Cucumi|cucumis|Cucumis (organism)
Genus Cucumis
C0331554
null
Hordeum vulgare (organism)|barley|hordeum vulgare|Hordeum vulgare
Hordeum vulgare
C1160601
The dehiscence of an anther to release the pollen grains contained within it. [GOC:tb]
null
anther dehiscence
C0032385
The fertilizing element of plants that contains the male GAMETOPHYTES.
Pollen Grains|Grain, Pollen|Pollen Grain|pollen|pollens|Pollens|Pollen (substance)|Grains, Pollen|Pollen
Pollen
C0064138
null
3-oxo-2-(2-pentenyl)cyclopentaneacetic acid
jasmonic acid
C0128062
null
jasmonic acid methyl ester|3-oxo-2-(2-pentenyl)cyclopentaneacetic acid methyl ester
methyl jasmonate
C0018494
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.
HAIR|Pili|hairs|hair structure|Hairs|Hair structure (body structure)|Hair structure|Set of hairs|hair|Hair|Hairs set|Hair, NOS
Hair
C0256591
null
3-butenoic acid, 2-amino-4-(2-aminoethoxy)-, (2S,3E)-|aviglycine
aminoethoxyvinylglycine
C0020740
A nonsteroidal anti-inflammatory agent with analgesic properties used in the treatment of RHEUMATISM and ARTHRITIS.
Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-|ibuprofen|2-(4-isobutylphenyl)propanoic acid|(.+ -.)-p-Isobutylhydratropic acid|(±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid|Ibuprofen-containing product|(±)-ibuprofen|(±)-2-(p-isobutylphenyl)propionic acid|IBUPROFEN|(RS)-ibuprofen|p-Isobutylhydratropic acid|(4-isobutylphenyl)-α-methylacetic acid|Ibuprophen|α-(4-isobutylphenyl)propionic acid|Product containing ibuprofen (medicinal product)|Ibuprofen (substance)|p-Isobutylhydratropic Acid|benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-|Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-|Ibuprofenum|p-isobutylhydratropic acid|4-isobutylhydratropic acid|alpha-Methyl-4-(2-methylpropyl)benzeneacetic Acid|α-(p-isobutylphenyl)propionic acid|(±)-p-isobutylhydratropic acid|ibuprofen products|Ibuprofene|Ibuprofeno|Ibuprofen
ibuprofen
C0073980
null
salicylhydroxamic acid (SHAM)|SHAM
salicylhydroxamic acid
C0009790
The cognitive and affective processes which constitute an internalized moral governor over an individual's moral conduct.
Consciences|Conscience|conscience
Conscience
C0009790
The cognitive and affective processes which constitute an internalized moral governor over an individual's moral conduct.
Consciences|Conscience|conscience
Conscience
C1176128
null
null
jasmonate
C0000843
Abscission-accelerating plant growth substance isolated from young cotton fruit, leaves of sycamore, birch, and other plants, and from potatoes, lemons, avocados, and other fruits.
Abscisic acid (substance)|Abscissic Acid|2,4-Pentadienoic acid, 5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-, (S-(Z,E))-|Abscissin|Abscisin|Abscissins|Abscisic acid
Abscisic Acid
C0678686
null
biological rest|dormancy
Dormancy
C1140676
A plant species of the family SOLANACEAE, native of South America, widely cultivated for their edible, fleshy, usually red fruit.
Solanum esculentum|Tomato|Lycopersicon esculentum|Solanum lycopersicum var. humboldtii|Lycopersicon esculentum var. esculentum|tomato|Solanum lycopersicum|tomatoes|Lycopersicon esculentum (organism)
Lycopersicon esculentum
C0017337
A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.
Gene (substance)|Gene|genes|Genes|GENE|Gene, NOS|gene
Genes
C0002180
null
Postpartum alopecia|Postpartum alopecia (disorder)|Alopecia, postpartum|Post-partum telogen effluvium
Postpartum alopecia
C0044281
null
1-Aminocyclopropane-1-carboxylate synthase|1-aminocyclopropane-1-carboxylate synthase (substance)|ACPCA synthase|S-adenosylmethionine methylthioadenosine-lyase (alpha, gamma-eliminating)|1-aminocyclopropanecarboxylate synthase|1-aminocyclopropane-1-carboxylate synthase|ACC-synthase
1-Aminocyclopropane-1-carboxylate synthase
C1427291
null
RNF121|ring finger protein 121|RNF121 gene|FLJ11099
RNF121 gene
C1427291
null
RNF121|ring finger protein 121|RNF121 gene|FLJ11099
RNF121 gene
C0002180
null
Postpartum alopecia|Postpartum alopecia (disorder)|Alopecia, postpartum|Post-partum telogen effluvium
Postpartum alopecia
C0812327
Genes that code for transcription factors.
Transcription Factor Gene|Proto-Oncogene, Transcription Factor
Transcription factor genes
C1140671
Annual cereal grass of the family POACEAE. Its starchy, EDIBLE GRAIN, rice, is the staple food of roughly one-half of the world's population.
Oryza sativa|rice plant|rice
Oryza sativa
C0812327
Genes that code for transcription factors.
Transcription Factor Gene|Proto-Oncogene, Transcription Factor
Transcription factor genes
C0227525
The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules.
Liver cells|hepatic cells|Cells, Hepatic|hepatocyte|hepatic cell|Hepatic parenchymal cell (cell)|hepatocytes|Hepatocyte|Cell, Hepatic|Hepatic Cell|Hepatocytus|liver cells|Liver cell|hepatic parenchymal cell|Hepatocytes|liver cell|Hepatic Cells|Hepatic parenchymal cell|Hepatic Parenchymal Cell
Hepatocyte
C0077063
A natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. Trichostatin A (TSA) reversibly and specifically inhibits histone deacetylases, resulting in hyperacetylation of core histones which modulate chromatin structure. The increase in histone acetylation promotes selective gene transcription and the inhibition of tumor growth. This agent is a potent inducer of tumor cell growth arrest, differentiation and apoptosis in a variety of transformed cells in culture and in tumor-bearing animals. (NCI04)
trichostatin a|(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide|trichostatin|tricostatin|trychostatin A|TSA antibioitc|tricostatin a|TRICHOSTATIN A|tricostatin A|Trichostatin A|7-(4-(dimethylamino)phenyl)-N-hydroxy- 4,6-dimethyl-7-oxo-2,4-heptadienamide
trichostatin A
C0077063
A natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. Trichostatin A (TSA) reversibly and specifically inhibits histone deacetylases, resulting in hyperacetylation of core histones which modulate chromatin structure. The increase in histone acetylation promotes selective gene transcription and the inhibition of tumor growth. This agent is a potent inducer of tumor cell growth arrest, differentiation and apoptosis in a variety of transformed cells in culture and in tumor-bearing animals. (NCI04)
trichostatin a|(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide|trichostatin|tricostatin|trychostatin A|TSA antibioitc|tricostatin a|TRICHOSTATIN A|tricostatin A|Trichostatin A|7-(4-(dimethylamino)phenyl)-N-hydroxy- 4,6-dimethyl-7-oxo-2,4-heptadienamide
trichostatin A
C0110611
A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Gap Junction Protein|Gap Junction Channel Proteins|connexins|Gap Junction Proteins|connexin|Junction Protein, Gap|Connexin|Connexins|Junction Proteins, Gap
Connexins
C0162640
null
Mozambique cichlid|Tilapia, Mozambique|Mozambique Tilapias|Mozambique mouthbrooder|largemouth tilapia|Chromis (Tilapia) mossambicus|Hawaiian sunfish|Tilapia mossambica|Oreochromis mossambicus (organism)|Tilapia mossambica (organism)|Oreochromis mossambicus|Mozambique Tilapia|Mozambique mouth-breeder|Mozambique tilapia|Sarotherodon mossambicus|Java tilapia|Hawaiian perch|Chromis mossambicus|Tilapias, Mozambique
Tilapia mossambica
C0376669
Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.
dna fragmentation|Fragmentation, DNA|DNA fragmentation|DNA Fragmentation
DNA Fragmentation
C0920532
null
null
gene induction
C0006556
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
cdna|Complementary DNA|Complementary deoxyribonucleic acid|cDNA|complementary DNA|complementary DNA (cDNA)|copies dna|Copy DNA|complementary dna|Complementary deoxyribonucleic acid (substance)
DNA, Complementary
C0026030
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.
Liver Microsomes|Microsome, Liver|Liver Microsome
Microsomes, Liver
C0036773
A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules.
albumin serum|Serum albumin|Albumin, Serum|serum albumin|Albumin, blood|Serum Albumin
Serum Albumin
C1619629
A drug used to treat too much iron in the blood caused by blood transfusions. It is being studied in the treatment of myelodysplastic syndromes (a group of diseases in which the bone marrow does not make enough healthy blood cells) and other conditions. Deferasirox binds to extra iron in the blood. The drug and the iron are passed from the body in urine. It is a type of chelating agent.
Deferasirox (substance)|Deferasirox|DEFERASIROX|Deferasiroxum|4-(3,5-Bis-(hydroxy-phenyl)-1,2,4-triazol-1-yl)-benzoic Acid|Deferasirox-containing product|4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid|Product containing deferasirox (medicinal product)|deferasirox
deferasirox
C0053374
null
Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|UDPGNAC-MAGtransferase III|beta-1,4-Mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase|N-Glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransterase III|UDPGNAC-glycopeptide beta4-N-acetylglucosaminyl transferase III|N-acetylglucosaminyltransferase III|UDP-N-acetylglucosamine-beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase III|Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (substance)|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III|beta-1,4-N-acetylglucosaminyltransferase III
beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
C0146712
null
Diponium Bromide|Dipenine Bromide|2,2-Dicyclopentylacetic Acid 2'-diethylaminoethyl Ester Ethobromide|triethyl(2-hydroxyethyl)ammonium bromide dicyclopentyl acetate|DIPONIUM BROMIDE
diponium bromide
C0146712
null
Diponium Bromide|Dipenine Bromide|2,2-Dicyclopentylacetic Acid 2'-diethylaminoethyl Ester Ethobromide|triethyl(2-hydroxyethyl)ammonium bromide dicyclopentyl acetate|DIPONIUM BROMIDE
diponium bromide
C0146712
null
Diponium Bromide|Dipenine Bromide|2,2-Dicyclopentylacetic Acid 2'-diethylaminoethyl Ester Ethobromide|triethyl(2-hydroxyethyl)ammonium bromide dicyclopentyl acetate|DIPONIUM BROMIDE
diponium bromide
C0206524
Self-replicating cytoplasmic organelles of plant and algal cells that contain pigments and may synthesize and accumulate various substances. PLASTID GENOMES are used in phylogenetic studies.
Plastid (cell structure)|Plastid|Plastids|Plastid, NOS|plastid
Plastids
C0007271
The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons containing 4 terpene subunits.
carotenoid|Carotenoids|Carotenoids (NOS)|Carotinoids|Carotinoid|Carotenoid|Carotinoid (substance)|carotenoids
Carotenoids
C0008260
Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.
Chlorophyll (substance)|Chlorophylls|CHLOROPHYLL|Chlorophyll|chlorophyll|chlorophylls
chlorophyll
C0031857
A blue-green biliprotein widely distributed in the plant kingdom.
Phytochrome|Phytochrome (substance)
Phytochrome
C0330098
null
Wild plant|Wild plant (organism)
Wild plant
C0010749
Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.
ferricytochrome C|Cytochrome c|Ferricytochrome c|ferrocytochrome C|Cytochromes c|cytochrome c|Ferrocytochrome c|cytochrome C
Cytochromes c
C0010749
Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.
ferricytochrome C|Cytochrome c|Ferricytochrome c|ferrocytochrome C|Cytochromes c|cytochrome c|Ferrocytochrome c|cytochrome C
Cytochromes c
C0011175
The condition that results from excessive loss of water from a living organism.
Pure water depletion syndrome|Dehydration (disorder)|dehydration|DEHYDRATION|loss of body water|exsiccosis|Dehydrated|deficient fluid volume|Dehydration|Dehydration syndrome|body water dehydration
Dehydration
C0242728
A group of plant cells that are capable of dividing infinitely and whose main function is the production of new growth at the growing tip of a root or stem. (From Concise Dictionary of Biology, 1990)
Meristems
Meristem
C0063100
null
HPO lyase|fatty acid hydroperoxide lyase
hydroperoxide lyase
C0303896
null
Blue light (physical force)|blue light|blue lights
Blue light
C0330502
A plant species of the family BRASSICACEAE best known for the edible roots.
oilseed rape|BRASSICA NAPUS SUBSP. NAPUS|Brassica napus|rapeseeds|Rape|Rapeseed|Brassica napus (organism)|Brassica napus L.|Canola|Rapeseeds|Oilseed rape|Turnip|Turnips
Brassica napus
C0031760
Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.
Photoreceptor|photoreceptor|Photoreceptor Cell|Photoreceptor cell|Photosensitive Cell|visual receptor|Cells, Photoreceptor|Photoreceptor Cells|Cell, Photoreceptor|photoreceptors|Photoreceptors
Photoreceptors
C0003069
Experimental organism whose genome has been altered by the transfer of a gene or genes from another species or breed.
Animal, Transgenic|Transgenic|Transgenic Animals|transgenic animals|transgenic animal|Animals, Transgenic|Transgenic Animal|animal transgenic|Transgenics|Transgenic animals
Animals, Transgenic
C0010028
A plant species of the family POACEAE. It is a tall grass grown for its EDIBLE GRAIN, corn, used as food and animal FODDER.
zea mays|corns|maize|Maize|Zea mays var. japonica|corn plant|Corn|Zea mays|corn|Zea mays (organism)
Zea mays
C0752312
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Mitogen-Activated Protein Kinase|Protein Kinases, Mitogen-Activated|Map Kinase|Mitogen Activated Protein Kinases|ERK|mapk|mitogen activated protein kinase (MAPK)|MAPK|map kinase|Mitogen-Activated Protein Kinases|MAP kinase|Extracellular Signal-Regulated Kinases|Kinases, Mitogen-Activated Protein|mitogen activated protein kinase|EC 2.7.2-|Mitogen-activated protein kinases
Mitogen-Activated Protein Kinases
C0017824
Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.
Glutathione-Disulfide Reductase|GSR - Glutathione reductase|Glutathione reductase|Reductase, Glutathione-Disulfide|glutathione reductase|Reductase, Glutathione|NADPH:oxidized-glutathione oxidoreductase|Glutathione Reductase|Glutathione reductase (reduced nicotinamide adenine dinucleotide phosphate)|Glutathione reductase (NAD(P)H)|Glutathione reductase (reduced nicotinamide adenine dinucleotide phosphate) (substance)
Glutathione Reductase
C0038838
An oxidoreductase that catalyzes the reaction between SUPEROXIDES and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide.
Erythrocuprein|superoxide dismutases|Hemocuprein|superoxide dismutase|sod|cytocuprein|Superoxide dismutase|SOD|E.C. 1.15.1.1|SUPEROXIDE DISMUTASE|Superoxide Dismutase (SOD)|Superoxide:superoxide oxidoreductase|Superoxide dismutase (substance)|Dismutase, Superoxide|super oxide dismutase|Superoxide Dismutase
superoxide dismutase
C0085536
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
Phosphotyrosine Phosphatase|Tyrosine Phosphatases, Protein|Protein-tyrosine-phosphate phosphohydrolase|Tyrosine O-Phosphate Phosphatase|protein tyrosine phosphate phosphohydrolase|Phosphatase, Protein-Tyrosine|Protein-tyrosine phosphatase|Tyrosine-Specific Protein Phosphatase|ptpase|Phosphotyrosine phosphatase|Protein Phosphotyrosine Phosphatase|Phosphatase, Tyrosyl Phosphoprotein|Phosphatases, Protein Tyrosine|Protein Tyrosine Phosphatases|Protein-Tyrosine Phosphatase|Protein-tyrosine-phosphatase|tyrosine phosphatase|PTP-Phosphatase|Phosphoprotein Phosphatase (Phosphotyrosine)|Phosphotyrosyl Protein Phosphatase|Protein Tyrosine Phosphatase|protein tyrosine phosphatase|Tyrosyl Phosphoprotein Phosphatase|PTPase|Protein-Tyrosine-Phosphatase|Phosphatase, Phosphotyrosyl Protein|Phosphoprotein Phosphatase, Tyrosyl|Phosphotyrosine Protein Phosphatase|phosphotyrosine phosphatase|Phosphotyrosylprotein Phosphatase|Tyrosylprotein Phosphatase|Protein-tyrosine-phosphatase (substance)|Phosphatase, Phosphotyrosine|PTPs|[Phosphotyrosine]Protein Phosphatase|PPT-Phosphatase|Protein Phosphatase, Phosphotyrosyl
Protein Tyrosine Phosphatase
C1564779
A family of chaperone proteins with subunit molecular masses of 12-43 kDa. The members are characterized by the presence of a highly conserved stretch of 80-100 amino acids in their C-terminal domains called the alpha-crystallin domain (ACD). Class I small heat shock proteins (sHsps) are widely expressed and play a role in cell survival. Class II sHsps are expressed in tissue-specific patterns and may be involved in the differentiation, development and specific functionality for the tissues they are expressed in.
sHsp|Small Heat-Shock Proteins|Small Heat Shock Protein|Heat Shock Protein Family B|Small Heat Shock Proteins|HSPB|Heat Shock Protein Family B (Small)|Small HSP Proteins|Heat Shock Proteins, Small|Small Heat Shock Protein Family|HSP Proteins, Small|sHSP Family
Heat-Shock Proteins, Small
C0030493
A poisonous dipyridilium compound used as contact herbicide. Contact with concentrated solutions causes irritation of the skin, cracking and shedding of the nails, and delayed healing of cuts and wounds.
4,4'-Bipyridinium, 1,1'-dimethyl-|Paraquat|Methyl Viologen|Paraquat (substance)|Viologen, Methyl|paraquat
Paraquat
C0002602
A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
Aminotriazole|1H-1,2,4-Triazol-3-Amine|1H-1,2,4-Triazol-3-amine|Aminotriazole (substance)|AMITROLE|ATA|3-Amino-1,2,4-triazole|3-Amino-1,2,4-Triazole|Amitrole
Amitrole
C0016832
A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.
Fungal|FUNGI: GENERAL TERMS|FUNGI|Kingdom Fungi|Mycete|fungal microorganisms|Fungus, NOS|Fungi|FUNGI - MYCETAE|FUNGUS|fungi|Fungus|Kingdom Fungi (organism)|fungal microorganism|fungus
Fungi