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24846454 | background | Vascular surgeons perform majority of EVAR . | 2 |
24846454 | background | There are no reports for the long-term results of this intervention performed by interventional cardiologists . | 3 |
24846454 | background | We present one of the first reports of periprocedural and long-term outcomes of EVAR performed by interventional cardiologists . | 4 |
24846454 | methods | Retrospective chart review on patients with attempted EVAR between September @ and January @ was performed . | 5 |
24846454 | methods | Included cases were all consecutive patients who had attempted EVAR by interventional cardiologists . | 6 |
24846454 | results | During the study period EVAR was attempted in @ patients , with @ % being women . | 7 |
24846454 | results | The mean age was @ years ( range @-@ ) . | 8 |
24846454 | results | The endovascular graft placement was successful in @ % ( @/@ ) of patients . | 9 |
24846454 | results | Procedure failures were more common in women ( @ of @ vs @ of @ , P = @ ) . | 10 |
24846454 | results | The @-day mortality was @ % ( @ of @ ) . | 11 |
24846454 | results | In patients with successful EVAR the mean follow-up was @ months and mean length of hospital stay was @ days . | 12 |
24846454 | results | Major periprocedural complications were noted in @ % patients ( @ of @ ) . | 13 |
24846454 | results | During follow-up , six patients ( @ % ) required re-intervention and additional @ patients died with no aneurysm related deaths . | 14 |
24846454 | conclusions | EVAR primarily performed by interventional cardiologists demonstrates high periprocedural and long-term success rates . | 15 |
24846454 | conclusions | A higher EVAR failure rate has been observed in women . | 16 |
24488838 | objective | Anorexia nervosa ( AN ) is a severe illness with high rates of relapse . | 0 |
24488838 | objective | Exposure and Response Prevention for AN ( AN-EXRP ) is a new approach that specifically addresses maladaptive eating behavior by targeting eating-related fear and anxiety . | 1 |
24488838 | objective | The aim of this study was to evaluate AN-EXRP as an adjunctive strategy to improve eating behavior during weight restoration , at a pivotal moment when treatment goals shift toward relapse prevention . | 2 |
24488838 | methods | A randomized controlled trial was conducted to compare AN-EXRP with a comparison condition , Cognitive Remediation Therapy ( CRT ) . | 3 |
24488838 | methods | Hospitalized patients with AN ( n = @ ) who had achieved weight restoration to a BMI > @ kg/m ( @ ) received @ sessions of either AN-EXRP or CRT . | 4 |
24488838 | methods | Outcome was assessed by change in caloric intake in an objective assessment of eating behavior . | 5 |
24488838 | results | The average test meal caloric intake of participants who received AN-EXRP increased from @ kcal at baseline to @ kcal post-treatment , while that of participants who received CRT decreased from @ kcal at baseline to @ kcal post-treatment -LSB- t ( @ ) = @ , p = @ -RSB- . | 6 |
24488838 | results | Improvement in intake was significantly associated with improvement in eating-related anxiety ( Spearman 's = @ , p = @ ) . | 7 |
24488838 | conclusions | These data demonstrate that AN-EXRP , compared to a credible comparison intervention , is associated with better caloric intake in a laboratory meal over time in AN . | 8 |
24488838 | conclusions | Additional studies are required to determine whether incorporation of these techniques into a longer treatment program leads to enduring and clinically significant change . | 9 |
25007421 | objective | Aggressive behaviour in psychosis is not uncommon . | 0 |
25007421 | objective | Community provision for people with psychosis has left informal caregivers to take on a greater role in their care . | 1 |
25007421 | objective | However , few studies have explored links between patient-initiated violence in mental health caregiving relationships and caregiver functioning . | 2 |
25007421 | objective | Our study investigated caregiver reports of aggressive acts committed by their relative with psychosis and their links to caregiver appraisals of the caregiving relationship and caregiver outcomes . | 3 |
25007421 | methods | Caregivers of patients with a recent relapse of psychosis , recruited to a psychological therapy trial , completed the audiotaped Camberwell Family Interview at baseline . | 4 |
25007421 | methods | This semi-structured interview includes questions on the quality of the relationship between caregiver and patient , and patient history of violence . | 5 |
25007421 | methods | Seventy-two transcripts of interviews were assessed for reports of patient-initiated violence . | 6 |
25007421 | results | One-half of the caregiver sample ( @ % ) reported an incident of patient-initiated violence during their interview ; @ % of these involved violence toward themselves , and @ % toward property . | 7 |
25007421 | results | Reports of patient violence were associated with caregiver ratings of hostility expressed toward patients , lower self-esteem , and emotion-focused coping . | 8 |
25007421 | results | People caring on their own were more likely to report incidents of patient violence . | 9 |
25007421 | results | Younger patients , males , and inpatients were more frequently identified as having a history of this kind of violence . | 10 |
25007421 | conclusions | Our findings suggested that caregiver reports of patient-initiated violence in psychosis are not uncommon . | 11 |
25007421 | conclusions | Mental health staff need to be aware of the risks of such violence for caregivers of people with psychosis , and consider appropriate procedures for minimizing it . | 12 |
24958362 | background | Positive-pressure ventilation during transport of intubated patients is generally delivered via a hand-pressurized device . | 0 |
24958362 | background | Of these devices , self-inflating resuscitators ( SIR ) and flow-inflating resuscitators ( FIR ) constitute the two major types used . | 1 |
24958362 | background | Selection of a particular device for transport , however , remains largely an institutional practice . | 2 |
24958362 | objective | To evaluate the hypothesis that transport ventilation goals of intubated pediatric patients are better achieved using an FIR compared to an SIR . | 3 |
24958362 | methods | This randomized crossover simulation study compared the performance of SIR and FIR among anesthesia providers in a pediatric transport scenario . | 4 |
24958362 | methods | Subjects hand-ventilated a test lung while simultaneously maneuvering a stretcher bed to simulate patient transport . | 5 |
24958362 | methods | Hand ventilation was carried out using a Jackson-Rees circuit ( FIR ) and a Laerdal pediatric silicone resuscitator ( SIR ) . | 6 |
24958362 | methods | The primary outcome was the proportion of total breaths delivered within the predefined target PIP/PEEP range ( @ + / - @ , @ + / - @ cm H@O ) . | 7 |
24958362 | methods | Secondary outcomes included proportion of total breaths delivered with operationally defined unacceptable breath variables ( PIP > @ cm H@O or PEEP < @ cm H@O ) . | 8 |
24958362 | results | Overall , participants were four times more likely to deliver target breaths and one-third less likely to deliver unacceptable breaths using the FIR compared to the SIR . | 9 |
24958362 | results | When comparing device performance , a @ % increase in the proportions of target breaths and a @ % decrease in unacceptable breaths using the FIR were observed ( P < @ for both ) . | 10 |
24958362 | conclusions | Hand ventilation during patient transport is superior using the FIR compared to the SIR to achieve target ventilatory goals and avoid unacceptable ventilatory cycles . | 11 |
25446547 | objective | To examine efficacy of hysteroscopic removal of polyps and myomas on health-related quality of life and symptom severity at @-year postprocedure . | 0 |
25446547 | methods | Randomized , prospective , comparative setting clinical trial ( Canadian Task Force classification II-@ ) . | 1 |
25446547 | methods | Nine outpatient obstetrics and gynecology practices and hospitals in the United States . | 2 |
25446547 | methods | Women @ to @years of age with polyps and/or type @ or I myomas @ and @ cm . | 3 |
25446547 | methods | Treatment of polyps and fibroids with the MyoSure device . | 4 |
25446547 | results | A total of @ lesions ( @ polyps , @ myomas ) were removed . | 5 |
25446547 | results | Among the @ pathologies removed , @ were removed in an office setting ( @ myomas , @ polyps ) , and @ were removed in an ambulatory surgical center ( ASC ) setting ( @ myomas , @ polyps ) . | 6 |
25446547 | results | The mean percentage of pathology removed was @ % for fibroids and @ @ % for polyps . | 7 |
25446547 | results | Symptom severity as measured by the Uterine Fibroid Symptom-Quality of Life ( UFS-QOL ) scale improved significantly ( p < @ ) between baseline ( mean score of @ ) and @months postprocedure ( mean score of @ ) . | 8 |
25446547 | results | The Health-Related Quality of Life ( HRQOL ) scale also improved significantly ( p < @ ) between baseline ( mean score @ ) and @months postprocedure ( mean score of @ ) . | 9 |
25446547 | results | Both the office and ASC groups demonstrated a statistically significant ( p < @ ) improvement in UFS-QOL and HRQOL . | 10 |
25446547 | conclusions | For women with intrauterine polyps and/or myomas who experienced abnormal uterine bleeding , hysteroscopic morcellation with the MyoSure device provided significant , durable health-related , quality-of-life improvements up to @months postprocedure . | 11 |
25446547 | conclusions | These findings were the same for patients treated in both an office-based setting and ASCs . | 12 |
24530651 | objective | To evaluate the effects of a home-monitoring device with tele-monitoring compared with standard care in detection of progression to choroidal neovascularization ( CNV ) associated with age-related macular degeneration ( AMD ) , the leading cause of blindness in the US . | 0 |
24530651 | methods | Participants , aged @ to @ years , at high risk of developing CNV associated with AMD were recruited to the HOme Monitoring of Eye ( HOME ) Study , an unmasked , multi-center , randomized trial of the ForeseeHome ( FH ) device plus standard care vs. standard care alone . | 1 |
24530651 | methods | The FH device utilizes preferential hyperacuity perimetry and tele-monitoring to detect changes in vision function associated with development of CNV , potentially prior to symptom and visual acuity loss . | 2 |
24530651 | methods | After establishing baseline measurements , subsequent changes on follow-up are detected by the device , causing the monitoring center to alert the clinical center to recall participants for an exam . | 3 |
24530651 | methods | Standard care consists of instructions for self-monitoring visual changes with subsequent self-report to the clinical center . | 4 |
24530651 | methods | The primary objective of this study is to determine whether home monitoring plus standard care in comparison with standard care alone , results in earlier detection of incident CNV with better present visual acuity . | 5 |
24530651 | methods | The primary outcome is the decline in visual acuity at CNV diagnosis from baseline . | 6 |
24530651 | methods | Detection of CNV prior to substantial vision loss is critical as vision outcome following anti-angiogenic therapy is dependent on the visual acuity at initiation of treatment . | 7 |
24530651 | conclusions | HOME Study is the first large scale study to test the use of home tele-monitoring system in the management of AMD patients . | 8 |
24807156 | background | Avastin Biomarkers In lunG And @D Innovative anaLysis ( ABIGAIL ) , which is a phase II , open-label , randomized study , investigated correlations between biomarkers and best overall response to bevacizumab plus platinum-doublet chemotherapy for patients with advanced/recurrent non-small-cell lung cancer . | 0 |
24807156 | methods | Patients received bevacizumab ( @ or @ mg/kg , @-weekly until disease progression/unacceptable toxicity ) plus carboplatin/gemcitabine or carboplatin/paclitaxel ( maximum six cycles ) . | 1 |
24807156 | methods | Plasma samples ( baseline/throughout treatment ) were analyzed for vascular endothelial growth factor ( VEGF ) - A ( baseline only ) , VEGF receptors ( VEGFR-@ / VEGFR-@ ) , basic fibroblast growth factor , E-selectin , intercellular adhesion molecule-@ , and placental growth factor ( baseline only ) . | 2 |
24807156 | methods | Tumor samples ( primary specimen ) were analyzed for VEGF-A , VEGFR-@ / VEGFR-@ , neuropilin ( NRP ) , and CD@ . | 3 |
24807156 | methods | Response was evaluated at baseline and every @ weeks ( Response Evaluation Criteria in Solid Tumors ) . | 4 |
24807156 | results | Patients were randomized to receive chemotherapy plus @ mg/kg ( n = @ ) or @ mg/kg ( n = @ ) bevacizumab . | 5 |
24807156 | results | For the primary analysis , none of the baseline plasma biomarkers correlated with best overall response . | 6 |
24807156 | results | Exploratory analyses showed that low VEGF-A levels were associated with longer progression-free survival ( @ versus @ months ; hazard ratio , @ ; @ % confidence intervals , @ to @ ; p = @ ) and overall survival ( @ versus @ months ; hazard ratio , @ ; @ % confidence interval , @-@ @ ; p = @ ) compared with these in high baseline plasma VEGF-A levels . | 7 |
24807156 | results | No plasma biomarkers changed significantly over time . | 8 |
24807156 | results | No significant correlations were observed between tumor biomarkers and clinical outcomes . | 9 |
24807156 | results | No new safety signals were observed . | 10 |
24807156 | conclusions | Baseline and/or dynamic changes in plasma basic fibroblast growth factor , E-selectin , intercellular adhesion molecule-@ , placental growth factor , VEGFR-@ and VEGFR-@ , and tumor biomarkers did not correlate statistically with treatment outcomes for bevacizumab plus chemotherapy . | 11 |
24807156 | conclusions | Only baseline plasma VEGF-A was significantly correlated with progression-free survival/overall survival . | 12 |
24716478 | background | Evidence from armed conflict settings points to high levels of intimate partner violence ( IPV ) against women . | 0 |
24716478 | background | Current knowledge on how to prevent IPV is limited-especially within war-affected settings . | 1 |
24716478 | background | To inform prevention programming on gender-based violence in settings affected by conflict , we evaluated the impact of adding a targeted men 's intervention to a community-based prevention programme in Cte d'Ivoire . | 2 |
24716478 | methods | We conducted a two-armed , non-blinded cluster randomized trial in Cte d'Ivoire among @ pair-matched communities spanning government-controlled , UN buffer , and rebel-controlled zones . | 3 |
24716478 | methods | The intervention communities received a @-week IPV prevention intervention using a men 's discussion group format . | 4 |
24716478 | methods | All communities received community-based prevention programmes . | 5 |
24716478 | methods | Baseline data were collected from couples in September @ ( pre-intervention ) and follow-up in March @ ( one year post-intervention ) . | 6 |
24716478 | methods | The primary trial outcome was women 's reported experiences of physical and/or sexual IPV in the last @ months . | 7 |
24716478 | methods | We also assessed men 's reported intention to use physical IPV , attitudes towards sexual IPV , use of hostility and conflict management skills , and participation in gendered household tasks . | 8 |
24716478 | methods | An adjusted cluster-level intention to treat analysis was used to compare outcomes between intervention and control communities at follow-up . | 9 |
24716478 | results | At follow-up , reported levels of physical and/or sexual IPV in the intervention arm had decreased compared to the control arm ( ARR @ , @ % CI @-@ @ , not significant ) . | 10 |
24716478 | results | Men participating in the intervention reported decreased intentions to use physical IPV ( ARR @ , @ % CI @-@ @ ) and improved attitudes toward sexual IPV ( ARR @ , @ % CI @-@ @ ) . | 11 |
24716478 | results | Significant differences were found between men in the intervention and control arms ' reported ability to control their hostility and manage conflict ( ARR @ , @ % CI @-@ @ ) , and participation in gendered household tasks ( ARR @ , @ % CI @-@ @ ) . | 12 |
24716478 | conclusions | This trial points to the value of adding interventions working with men alongside community activities to reduce levels of IPV in conflict-affected settings . | 13 |
24716478 | conclusions | The intervention significantly influenced men 's reported behaviours related to hostility and conflict management and gender equitable behaviours . | 14 |
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