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{ "aliases": null, "definition": null, "id": "SpursOfRadialDiaphysis", "label": "Spurs of radial diaphysis", "logical_definition": null, "original_id": "HP:0004028", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfRadialDiaphysis" } ] }
0
{ "document": "Spurs of radial diaphysis None [{'predicate': 'subClassOf', 'target': 'AbnormalityOfRadialDiaphysis'}]" }
{ "aliases": null, "definition": "An increased proportion of eosinophils in sputum in the differentiated cell count.", "id": "SputumEosinophilia", "label": "Sputum eosinophilia", "logical_definition": null, "original_id": "HP:0032017", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSputum" } ] }
0
{ "document": "Sputum eosinophilia An increased proportion of eosinophils in sputum in the differentiated cell count. [{'predicate': 'subClassOf', 'target': 'AbnormalSputum'}]" }
{ "aliases": null, "definition": "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration.", "id": "Squalene", "label": "squalene", "logical_definition": null, "original_id": "CHEBI:15440", "relationships": [ { "predicate": "HasRole", "target": "MouseMetabolite" }, { "predicate": "HasRole", "target": "SaccharomycesCerevisiaeMetabolite" }, { "predicate": "HasRole", "target": "PlantMetabolite" }, { "predicate": "HasRole", "target": "HumanMetabolite" }, { "predicate": "subClassOf", "target": "Triterpene" } ] }
0
{ "document": "squalene A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. [{'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'SaccharomycesCerevisiaeMetabolite'}, {'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'subClassOf', 'target': 'Triterpene'}]" }
{ "aliases": null, "definition": "The articulation of the squamous portion of the temporal bones with the parietal bones[MP]. The squamosal suture arches backward from the pterion and connects the temporal squama with the lower border of the parietal: this suture is continuous behind with the short, nearly horizontal parietomastoid suture, which unites the mastoid process of the temporal with the region of the mastoid angle of the parietal[WP].", "id": "SquamoparietalSuture", "label": "squamoparietal suture", "logical_definition": null, "original_id": "UBERON:0003954", "relationships": [ { "predicate": "ContinuousWith", "target": "ParietomastoidSuture" } ] }
0
{ "document": "squamoparietal suture The articulation of the squamous portion of the temporal bones with the parietal bones[MP]. The squamosal suture arches backward from the pterion and connects the temporal squama with the lower border of the parietal: this suture is continuous behind with the short, nearly horizontal parietomastoid suture, which unites the mastoid process of the temporal with the region of the mastoid angle of the parietal[WP]. [{'predicate': 'ContinuousWith', 'target': 'ParietomastoidSuture'}]" }
{ "aliases": null, "definition": "The presence of squamous cell carcinoma of the skin.", "id": "SquamousCellCarcinoma", "label": "Squamous cell carcinoma", "logical_definition": null, "original_id": "HP:0002860", "relationships": [ { "predicate": "subClassOf", "target": "NeoplasmOfTheSkin" } ] }
0
{ "document": "Squamous cell carcinoma The presence of squamous cell carcinoma of the skin. [{'predicate': 'subClassOf', 'target': 'NeoplasmOfTheSkin'}]" }
{ "aliases": null, "definition": "Squamous cell carcinoma of the skin is a malignant tumor of squamous epithelium.", "id": "SquamousCellCarcinomaOfTheSkin", "label": "Squamous cell carcinoma of the skin", "logical_definition": null, "original_id": "HP:0006739", "relationships": [ { "predicate": "subClassOf", "target": "SquamousCellCarcinoma" } ] }
0
{ "document": "Squamous cell carcinoma of the skin Squamous cell carcinoma of the skin is a malignant tumor of squamous epithelium. [{'predicate': 'subClassOf', 'target': 'SquamousCellCarcinoma'}]" }
{ "aliases": null, "definition": "A carcinoma derived from a squamous epithelial cell of the tongue.", "id": "SquamousCellCarcinomaOfTheTongue", "label": "Squamous cell carcinoma of the tongue", "logical_definition": null, "original_id": "HP:0030413", "relationships": [ { "predicate": "subClassOf", "target": "NeoplasmOfTheTongue" } ] }
0
{ "document": "Squamous cell carcinoma of the tongue A carcinoma derived from a squamous epithelial cell of the tongue. [{'predicate': 'subClassOf', 'target': 'NeoplasmOfTheTongue'}]" }
{ "aliases": null, "definition": "A cancer that originates in the squamous cells that line the surface of the vulva.", "id": "SquamousCellCarcinomaOfTheVulva", "label": "Squamous cell carcinoma of the vulva", "logical_definition": null, "original_id": "HP:0030417", "relationships": [ { "predicate": "subClassOf", "target": "VulvarNeoplasm" } ] }
0
{ "document": "Squamous cell carcinoma of the vulva A cancer that originates in the squamous cells that line the surface of the vulva. [{'predicate': 'subClassOf', 'target': 'VulvarNeoplasm'}]" }
{ "aliases": null, "definition": "A type of non-small cell lung carcinoma that is derived from stratified squamous epithelial cells.", "id": "SquamousCellLungCarcinoma", "label": "Squamous cell lung carcinoma", "logical_definition": null, "original_id": "HP:0030359", "relationships": [ { "predicate": "subClassOf", "target": "NonSmallCellLungCarcinoma" } ] }
0
{ "document": "Squamous cell lung carcinoma A type of non-small cell lung carcinoma that is derived from stratified squamous epithelial cells. [{'predicate': 'subClassOf', 'target': 'NonSmallCellLungCarcinoma'}]" }
{ "aliases": null, "definition": null, "id": "SquamousEpithelialCell", "label": "squamous epithelial cell", "logical_definition": null, "original_id": "CL:0000076", "relationships": [ { "predicate": "subClassOf", "target": "EpithelialCell" } ] }
0
{ "document": "squamous epithelial cell None [{'predicate': 'subClassOf', 'target': 'EpithelialCell'}]" }
{ "aliases": null, "definition": "An epithelium characterised by its most superficial layer consisting of squamous epithelial cells.", "id": "SquamousEpithelium", "label": "squamous epithelium", "logical_definition": null, "original_id": "UBERON:0006914", "relationships": null }
0
{ "document": "squamous epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. None" }
{ "aliases": null, "definition": "Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia).", "id": "SquamousHyperplasia", "label": "squamous hyperplasia", "logical_definition": null, "original_id": "MPATH:149", "relationships": [ { "predicate": "subClassOf", "target": "HyperplasticTissue" } ] }
0
{ "document": "squamous hyperplasia Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia). [{'predicate': 'subClassOf', 'target': 'HyperplasticTissue'}]" }
{ "aliases": null, "definition": "A benign epithelial neoplasm characterized by a papillary growth pattern and a proliferation of neoplastic squamous cells without morphologic evidence of malignancy [NCI thesaurus].", "id": "SquamousPapilloma", "label": "Squamous Papilloma", "logical_definition": null, "original_id": "HP:0031021", "relationships": [ { "predicate": "subClassOf", "target": "Papilloma" } ] }
0
{ "document": "Squamous Papilloma A benign epithelial neoplasm characterized by a papillary growth pattern and a proliferation of neoplastic squamous cells without morphologic evidence of malignancy [NCI thesaurus]. [{'predicate': 'subClassOf', 'target': 'Papilloma'}]" }
{ "aliases": null, "definition": "A bone which is fused with the temporal bone in many mammals and forms part of the cheek region articulating with quadrate and pterygoid in other vertebrates.", "id": "SquamousPartOfTemporalBone", "label": "squamous part of temporal bone", "logical_definition": null, "original_id": "UBERON:0001695", "relationships": [ { "predicate": "PartOf", "target": "TemporalBone" }, { "predicate": "PartOf", "target": "Dermatocranium" }, { "predicate": "PartOf", "target": "VaultOfSkull" }, { "predicate": "DevelopsFrom", "target": "SquamousPartOfTemporalBonePrimordium" }, { "predicate": "ContributesToMorphologyOf", "target": "TemporalBone" }, { "predicate": "subClassOf", "target": "IntramembranousBone" } ] }
0
{ "document": "squamous part of temporal bone A bone which is fused with the temporal bone in many mammals and forms part of the cheek region articulating with quadrate and pterygoid in other vertebrates. [{'predicate': 'PartOf', 'target': 'TemporalBone'}, {'predicate': 'PartOf', 'target': 'Dermatocranium'}, {'predicate': 'PartOf', 'target': 'VaultOfSkull'}, {'predicate': 'DevelopsFrom', 'target': 'SquamousPartOfTemporalBonePrimordium'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'TemporalBone'}, {'predicate': 'subClassOf', 'target': 'IntramembranousBone'}]" }
{ "aliases": null, "definition": null, "id": "SquamousPartOfTemporalBonePrimordium", "label": "squamous part of temporal bone primordium", "logical_definition": null, "original_id": "UBERON:0010751", "relationships": [ { "predicate": "PartOf", "target": "VaultOfSkull" }, { "predicate": "DevelopsFrom", "target": "MesenchymeDerivedFromHeadNeuralCrest" } ] }
0
{ "document": "squamous part of temporal bone primordium None [{'predicate': 'PartOf', 'target': 'VaultOfSkull'}, {'predicate': 'DevelopsFrom', 'target': 'MesenchymeDerivedFromHeadNeuralCrest'}]" }
{ "aliases": null, "definition": "A shape quality inhering in a bearer by virtue of the bearer's having an equal-sided rectangular form.", "id": "Square", "label": "square", "logical_definition": null, "original_id": "PATO:0000413", "relationships": [ { "predicate": "subClassOf", "target": "Parallelogram" } ] }
0
{ "document": "square A shape quality inhering in a bearer by virtue of the bearer's having an equal-sided rectangular form. [{'predicate': 'subClassOf', 'target': 'Parallelogram'}]" }
{ "aliases": null, "definition": "Facial contours, as viewed from the front, show a broad upper face/cranium and lower face/mandible, creating a square appearance.", "id": "SquareFace", "label": "Square face", "logical_definition": null, "original_id": "HP:0000321", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalFacialShape" } ] }
0
{ "document": "Square face Facial contours, as viewed from the front, show a broad upper face/cranium and lower face/mandible, creating a square appearance. [{'predicate': 'subClassOf', 'target': 'AbnormalFacialShape'}]" }
{ "aliases": null, "definition": null, "id": "SquareHumeralMetaphysis", "label": "Square humeral metaphysis", "logical_definition": null, "original_id": "HP:0003923", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalHumeralMetaphysisMorphology" } ] }
0
{ "document": "Square humeral metaphysis None [{'predicate': 'subClassOf', 'target': 'AbnormalHumeralMetaphysisMorphology'}]" }
{ "aliases": null, "definition": "An abnormally squared appearance of the bony pelvis, a normally rounded or basin-shaped structure.", "id": "SquarePelvisBone", "label": "Square pelvis bone", "logical_definition": null, "original_id": "HP:0003278", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalPelvisBoneMorphology" } ] }
0
{ "document": "Square pelvis bone An abnormally squared appearance of the bony pelvis, a normally rounded or basin-shaped structure. [{'predicate': 'subClassOf', 'target': 'AbnormalPelvisBoneMorphology'}]" }
{ "aliases": null, "definition": "Square wave jerks are saccadic eye movements which, when recorded with open eyes are considered to be a pathological sign, caused by fixation instability, and pointing to a central neurological lesion.", "id": "SquareWaveJerks", "label": "Square-wave jerks", "logical_definition": null, "original_id": "HP:0025402", "relationships": [ { "predicate": "subClassOf", "target": "SaccadicIntrusion" } ] }
0
{ "document": "Square-wave jerks Square wave jerks are saccadic eye movements which, when recorded with open eyes are considered to be a pathological sign, caused by fixation instability, and pointing to a central neurological lesion. [{'predicate': 'subClassOf', 'target': 'SaccadicIntrusion'}]" }
{ "aliases": null, "definition": "A shift from the normally round (convex) appearance of the iliac wing towards a square-like appearance.", "id": "SquaredIliacBones", "label": "Squared iliac bones", "logical_definition": null, "original_id": "HP:0003177", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalIliumMorphology" } ] }
0
{ "document": "Squared iliac bones A shift from the normally round (convex) appearance of the iliac wing towards a square-like appearance. [{'predicate': 'subClassOf', 'target': 'AbnormalIliumMorphology'}]" }
{ "aliases": null, "definition": null, "id": "SquaredOffPlatyspondyly", "label": "Squared-off platyspondyly", "logical_definition": null, "original_id": "HP:0008418", "relationships": [ { "predicate": "subClassOf", "target": "Platyspondyly" } ] }
0
{ "document": "Squared-off platyspondyly None [{'predicate': 'subClassOf', 'target': 'Platyspondyly'}]" }
{ "aliases": null, "definition": "Flattening instead of curving or rounded superior helix, allowing the superior helix to run more horizontally than usual.", "id": "SquaredSuperiorPortionOfHelix", "label": "Squared superior portion of helix", "logical_definition": null, "original_id": "HP:0030026", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalHelixMorphology" } ] }
0
{ "document": "Squared superior portion of helix Flattening instead of curving or rounded superior helix, allowing the superior helix to run more horizontally than usual. [{'predicate': 'subClassOf', 'target': 'AbnormalHelixMorphology'}]" }
{ "aliases": null, "definition": "Squawks are short inspiratory wheezes of less than 200 ms duration and are also known as squeaks. Acoustic analysis shows the fundamental frequency varying between 200 and 300 Hz. Squawks usually occur in late inspiration and are often preceded by late inspiratory crackles.", "id": "Squawks", "label": "Squawks", "logical_definition": null, "original_id": "HP:0031995", "relationships": [ { "predicate": "subClassOf", "target": "Wheezing" } ] }
0
{ "document": "Squawks Squawks are short inspiratory wheezes of less than 200 ms duration and are also known as squeaks. Acoustic analysis shows the fundamental frequency varying between 200 and 300 Hz. Squawks usually occur in late inspiration and are often preceded by late inspiratory crackles. [{'predicate': 'subClassOf', 'target': 'Wheezing'}]" }
{ "aliases": null, "definition": "This modifier can be applied to a phenotypic feature that does not vary in severity or amount over time.", "id": "Stable", "label": "Stable", "logical_definition": null, "original_id": "HP:0031915", "relationships": [ { "predicate": "subClassOf", "target": "TemporalPattern" } ] }
0
{ "document": "Stable This modifier can be applied to a phenotypic feature that does not vary in severity or amount over time. [{'predicate': 'subClassOf', 'target': 'TemporalPattern'}]" }
{ "aliases": null, "definition": "A type of cry that is abnormal because it is consists of unusually shortened and detached vocalizations.", "id": "StaccatoCry", "label": "Staccato cry", "logical_definition": null, "original_id": "HP:0025431", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalCry" } ] }
0
{ "document": "Staccato cry A type of cry that is abnormal because it is consists of unusually shortened and detached vocalizations. [{'predicate': 'subClassOf', 'target': 'AbnormalCry'}]" }
{ "aliases": null, "definition": "A type of chronic kidney disease with normal or increased glomerular filtration rate (GFR at least 90 mL/min/1.73 m2).", "id": "Stage1ChronicKidneyDisease", "label": "Stage 1 chronic kidney disease", "logical_definition": null, "original_id": "HP:0012623", "relationships": [ { "predicate": "subClassOf", "target": "ChronicKidneyDisease" } ] }
0
{ "document": "Stage 1 chronic kidney disease A type of chronic kidney disease with normal or increased glomerular filtration rate (GFR at least 90 mL/min/1.73 m2). [{'predicate': 'subClassOf', 'target': 'ChronicKidneyDisease'}]" }
{ "aliases": null, "definition": "A type of chronic kidney disease with mildly reduced glomerular filtration rate (GFR 60-89 mL/min/1.73 m2).", "id": "Stage2ChronicKidneyDisease", "label": "Stage 2 chronic kidney disease", "logical_definition": null, "original_id": "HP:0012624", "relationships": [ { "predicate": "subClassOf", "target": "ChronicKidneyDisease" } ] }
0
{ "document": "Stage 2 chronic kidney disease A type of chronic kidney disease with mildly reduced glomerular filtration rate (GFR 60-89 mL/min/1.73 m2). [{'predicate': 'subClassOf', 'target': 'ChronicKidneyDisease'}]" }
{ "aliases": null, "definition": "A type of chronic kidney disease with moderately reduced glomerular filtration rate (GFR 30-59 mL/min/1.73 m2).", "id": "Stage3ChronicKidneyDisease", "label": "Stage 3 chronic kidney disease", "logical_definition": null, "original_id": "HP:0012625", "relationships": [ { "predicate": "subClassOf", "target": "ChronicKidneyDisease" } ] }
0
{ "document": "Stage 3 chronic kidney disease A type of chronic kidney disease with moderately reduced glomerular filtration rate (GFR 30-59 mL/min/1.73 m2). [{'predicate': 'subClassOf', 'target': 'ChronicKidneyDisease'}]" }
{ "aliases": null, "definition": "A type of chronic kidney disease with severely reduced glomerular filtration rate (GFR 15-29 mL/min/1.73 m2).", "id": "Stage4ChronicKidneyDisease", "label": "Stage 4 chronic kidney disease", "logical_definition": null, "original_id": "HP:0012626", "relationships": [ { "predicate": "subClassOf", "target": "ChronicKidneyDisease" } ] }
0
{ "document": "Stage 4 chronic kidney disease A type of chronic kidney disease with severely reduced glomerular filtration rate (GFR 15-29 mL/min/1.73 m2). [{'predicate': 'subClassOf', 'target': 'ChronicKidneyDisease'}]" }
{ "aliases": null, "definition": "A degree of kidney failure severe enough to require dialysis or kidney transplantation for survival characterized by a severe reduction in glomerular filtration rate (less than 15 ml/min/1.73 m2) and other manifestations including increased serum creatinine.", "id": "Stage5ChronicKidneyDisease", "label": "Stage 5 chronic kidney disease", "logical_definition": null, "original_id": "HP:0003774", "relationships": [ { "predicate": "subClassOf", "target": "ChronicKidneyDisease" } ] }
0
{ "document": "Stage 5 chronic kidney disease A degree of kidney failure severe enough to require dialysis or kidney transplantation for survival characterized by a severe reduction in glomerular filtration rate (less than 15 ml/min/1.73 m2) and other manifestations including increased serum creatinine. [{'predicate': 'subClassOf', 'target': 'ChronicKidneyDisease'}]" }
{ "aliases": null, "definition": "Large branching stones that fill part of all of the renal pelvis and renal calyces and they can be complete or partial depending on the level of occupancy of the collecting system.", "id": "StaghornCalculus", "label": "Staghorn calculus", "logical_definition": null, "original_id": "HP:0033591", "relationships": [ { "predicate": "subClassOf", "target": "Nephrolithiasis" } ] }
0
{ "document": "Staghorn calculus Large branching stones that fill part of all of the renal pelvis and renal calyces and they can be complete or partial depending on the level of occupancy of the collecting system. [{'predicate': 'subClassOf', 'target': 'Nephrolithiasis'}]" }
{ "aliases": null, "definition": "The presence of a supernumerary, i.e. third, crus of the helix in the helix, arising at or above the normal bifurcation of the antihelix.", "id": "StahlEar", "label": "Stahl ear", "logical_definition": null, "original_id": "HP:0100015", "relationships": [ { "predicate": "subClassOf", "target": "AdditionalCrusOfAntihelix" } ] }
0
{ "document": "Stahl ear The presence of a supernumerary, i.e. third, crus of the helix in the helix, arising at or above the normal bifurcation of the antihelix. [{'predicate': 'subClassOf', 'target': 'AdditionalCrusOfAntihelix'}]" }
{ "aliases": null, "definition": "The muscle that stabilizes the stapes bone. The stapedius emerges from a pinpoint foramen in the apex of the pyramidal eminence (a hollow, cone-shaped prominence in the posterior wall of the tympanic cavity), and inserts into the neck of the stapes. [WP,unvetted].", "id": "StapediusMuscle", "label": "stapedius muscle", "logical_definition": null, "original_id": "UBERON:0001599", "relationships": [ { "predicate": "PartOf", "target": "MiddleEar" }, { "predicate": "InnervatedBy", "target": "FacialNerve" }, { "predicate": "DevelopsFrom", "target": "StapediusPreMuscleCondensation" }, { "predicate": "HasMuscleInsertion", "target": "StapesBone" } ] }
0
{ "document": "stapedius muscle The muscle that stabilizes the stapes bone. The stapedius emerges from a pinpoint foramen in the apex of the pyramidal eminence (a hollow, cone-shaped prominence in the posterior wall of the tympanic cavity), and inserts into the neck of the stapes. [WP,unvetted]. [{'predicate': 'PartOf', 'target': 'MiddleEar'}, {'predicate': 'InnervatedBy', 'target': 'FacialNerve'}, {'predicate': 'DevelopsFrom', 'target': 'StapediusPreMuscleCondensation'}, {'predicate': 'HasMuscleInsertion', 'target': 'StapesBone'}]" }
{ "aliases": null, "definition": null, "id": "StapediusPreMuscleCondensation", "label": "stapedius pre-muscle condensation", "logical_definition": null, "original_id": "UBERON:0010929", "relationships": [ { "predicate": "PartOf", "target": "MiddleEar" }, { "predicate": "DevelopsFrom", "target": "MesenchymeOfMiddleEar" }, { "predicate": "subClassOf", "target": "PreMuscleCondensation" } ] }
0
{ "document": "stapedius pre-muscle condensation None [{'predicate': 'PartOf', 'target': 'MiddleEar'}, {'predicate': 'DevelopsFrom', 'target': 'MesenchymeOfMiddleEar'}, {'predicate': 'subClassOf', 'target': 'PreMuscleCondensation'}]" }
{ "aliases": null, "definition": "Stapes ankylosis refers to congenital or acquired fixation of the stapes (the stirrup-shaped small bone or ossicle in the middle ear), which is associated with conductive hearing resulting from impairment of the sound-conduction mechanism (the external auditory canal, tympanic membrane, and/or middle-ear ossicles).", "id": "StapesAnkylosis", "label": "Stapes ankylosis", "logical_definition": null, "original_id": "HP:0000381", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTheStapes" } ] }
0
{ "document": "Stapes ankylosis Stapes ankylosis refers to congenital or acquired fixation of the stapes (the stirrup-shaped small bone or ossicle in the middle ear), which is associated with conductive hearing resulting from impairment of the sound-conduction mechanism (the external auditory canal, tympanic membrane, and/or middle-ear ossicles). [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheStapes'}]" }
{ "aliases": null, "definition": "The stapes or stirrup is the stirrup-shaped small bone or ossicle in the middle ear which is attached to the incus laterally and to the fenestra ovalis, the 'oval window' medially. The oval window is adjacent to the vestibule of the inner ear. The stapes is the smallest and lightest bone in the human body. The stapes transmits the sound vibrations from the incus to the membrane of the inner ear inside the fenestra ovalis. The stapes is also stabilized by the stapedius muscle, which is innervated by the facial nerve. In non-mammalian vertebrates, the bone homologous to the stapes is usually called the columella; however, in reptiles, either term may be used[WP,unvetted].", "id": "StapesBone", "label": "stapes bone", "logical_definition": null, "original_id": "UBERON:0001687", "relationships": [ { "predicate": "DevelopsFrom", "target": "ReichertSCartilage" }, { "predicate": "DevelopsFrom", "target": "StapesCartilageElement" } ] }
0
{ "document": "stapes bone The stapes or stirrup is the stirrup-shaped small bone or ossicle in the middle ear which is attached to the incus laterally and to the fenestra ovalis, the 'oval window' medially. The oval window is adjacent to the vestibule of the inner ear. The stapes is the smallest and lightest bone in the human body. The stapes transmits the sound vibrations from the incus to the membrane of the inner ear inside the fenestra ovalis. The stapes is also stabilized by the stapedius muscle, which is innervated by the facial nerve. In non-mammalian vertebrates, the bone homologous to the stapes is usually called the columella; however, in reptiles, either term may be used[WP,unvetted]. [{'predicate': 'DevelopsFrom', 'target': 'ReichertSCartilage'}, {'predicate': 'DevelopsFrom', 'target': 'StapesCartilageElement'}]" }
{ "aliases": null, "definition": "A stapes endochondral element that is composed primarily of cartilage tissue.", "id": "StapesCartilageElement", "label": "stapes cartilage element", "logical_definition": null, "original_id": "UBERON:0010055", "relationships": [ { "predicate": "PartOf", "target": "AuditoryOssicleBone" }, { "predicate": "DevelopsFrom", "target": "StapesPreCartilageCondensation" }, { "predicate": "subClassOf", "target": "HyomandibularCartilage" } ] }
0
{ "document": "stapes cartilage element A stapes endochondral element that is composed primarily of cartilage tissue. [{'predicate': 'PartOf', 'target': 'AuditoryOssicleBone'}, {'predicate': 'DevelopsFrom', 'target': 'StapesPreCartilageCondensation'}, {'predicate': 'subClassOf', 'target': 'HyomandibularCartilage'}]" }
{ "aliases": null, "definition": "A stapes bone or its cartilage or pre-cartilage precursor.", "id": "StapesEndochondralElement", "label": "stapes endochondral element", "logical_definition": null, "original_id": "UBERON:0015016", "relationships": [ { "predicate": "subClassOf", "target": "AuditoryOssicleEndochondralElement" } ] }
0
{ "document": "stapes endochondral element A stapes bone or its cartilage or pre-cartilage precursor. [{'predicate': 'subClassOf', 'target': 'AuditoryOssicleEndochondralElement'}]" }
{ "aliases": null, "definition": "A stapes endochondral element that is composed primarily of a pre-cartilage condensation.", "id": "StapesPreCartilageCondensation", "label": "stapes pre-cartilage condensation", "logical_definition": null, "original_id": "UBERON:0006294", "relationships": [ { "predicate": "PartOf", "target": "AuditoryOssicleBone" }, { "predicate": "DevelopsFrom", "target": "2ndArchMesenchyme" } ] }
0
{ "document": "stapes pre-cartilage condensation A stapes endochondral element that is composed primarily of a pre-cartilage condensation. [{'predicate': 'PartOf', 'target': 'AuditoryOssicleBone'}, {'predicate': 'DevelopsFrom', 'target': '2ndArchMesenchyme'}]" }
{ "aliases": null, "definition": "An inability to digest starch.", "id": "StarchIntolerance", "label": "Starch intolerance", "logical_definition": null, "original_id": "HP:0041049", "relationships": [ { "predicate": "subClassOf", "target": "Malabsorption" } ] }
0
{ "document": "Starch intolerance An inability to digest starch. [{'predicate': 'subClassOf', 'target': 'Malabsorption'}]" }
{ "aliases": null, "definition": "An abnormality in which the eyes are held permanently wide open.", "id": "StaringGaze", "label": "Staring gaze", "logical_definition": null, "original_id": "HP:0025401", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalEyePhysiology" } ] }
0
{ "document": "Staring gaze An abnormality in which the eyes are held permanently wide open. [{'predicate': 'subClassOf', 'target': 'AbnormalEyePhysiology'}]" }
{ "aliases": null, "definition": "An abnormal echotexture visible in liver ultrasound manifesting as a diffuse hyperechoic liver echotexture with multiple, small hypoechoic lesions. The appearance is said to resemble a starry sky (multiple white spots on a dark background).", "id": "StarrySkyAppearanceOnHepaticSonography", "label": "Starry sky appearance on hepatic sonography", "logical_definition": null, "original_id": "HP:0031145", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalLiverSonography" } ] }
0
{ "document": "Starry sky appearance on hepatic sonography An abnormal echotexture visible in liver ultrasound manifesting as a diffuse hyperechoic liver echotexture with multiple, small hypoechoic lesions. The appearance is said to resemble a starry sky (multiple white spots on a dark background). [{'predicate': 'subClassOf', 'target': 'AbnormalLiverSonography'}]" }
{ "aliases": null, "definition": "Startle-induced seizures are triggered by multiple and non-specific stimuli (auditory, somatosensory, and rarely visual) and are characterized by their sudden unexpected nature. Sudden noise rather than pure sound is the most effective acoustic stimulus.", "id": "StartleInducedSeizure", "label": "Startle-induced seizure", "logical_definition": null, "original_id": "HP:0020214", "relationships": [ { "predicate": "subClassOf", "target": "ReflexSeizure" } ] }
0
{ "document": "Startle-induced seizure Startle-induced seizures are triggered by multiple and non-specific stimuli (auditory, somatosensory, and rarely visual) and are characterized by their sudden unexpected nature. Sudden noise rather than pure sound is the most effective acoustic stimulus. [{'predicate': 'subClassOf', 'target': 'ReflexSeizure'}]" }
{ "aliases": null, "definition": "An action or movement due to the application of a sudden unexpected stimulus.", "id": "StartleResponse", "label": "startle response", "logical_definition": null, "original_id": "GO:0001964", "relationships": [ { "predicate": "subClassOf", "target": "ResponseToExternalStimulus" }, { "predicate": "subClassOf", "target": "NeuromuscularProcess" } ] }
0
{ "document": "startle response An action or movement due to the application of a sudden unexpected stimulus. [{'predicate': 'subClassOf', 'target': 'ResponseToExternalStimulus'}, {'predicate': 'subClassOf', 'target': 'NeuromuscularProcess'}]" }
{ "aliases": null, "definition": "inverse of starts with", "id": "Starts", "label": "starts", "logical_definition": null, "original_id": "RO:0002223", "relationships": [ { "predicate": "subPropertyOf", "target": "PartOf" }, { "predicate": "subPropertyOf", "target": "TemporallyRelatedTo" }, { "predicate": "owl:inverseOf", "target": "StartsWith" } ] }
0
{ "document": "starts inverse of starts with [{'predicate': 'subPropertyOf', 'target': 'PartOf'}, {'predicate': 'subPropertyOf', 'target': 'TemporallyRelatedTo'}, {'predicate': 'owl:inverseOf', 'target': 'StartsWith'}]" }
{ "aliases": null, "definition": "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.", "id": "StartsWith", "label": "starts with", "logical_definition": null, "original_id": "RO:0002224", "relationships": [ { "predicate": "subPropertyOf", "target": "HasPart" }, { "predicate": "subPropertyOf", "target": "TemporallyRelatedTo" } ] }
0
{ "document": "starts with x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. [{'predicate': 'subPropertyOf', 'target': 'HasPart'}, {'predicate': 'subPropertyOf', 'target': 'TemporallyRelatedTo'}]" }
{ "aliases": null, "definition": "Stasis dermatitis commonly occurs in older age. It is caused by venous hypertension resulting from retrograde flow due to incompetent venous valves, valve destruction, or obstruction of the venous system. Further tissue changes arise from an inflammatory process mediated by metalloproteinases, which are up-regulated by ferric ion from extravasated red blood cells. Stasis dermatitis presents initially as poorly demarcated erythematous plaques of the lower legs bilaterally, classically involving the medial malleolus.", "id": "StasisDermatitis", "label": "Stasis dermatitis", "logical_definition": null, "original_id": "HP:0033564", "relationships": [ { "predicate": "subClassOf", "target": "Eczema" } ] }
0
{ "document": "Stasis dermatitis Stasis dermatitis commonly occurs in older age. It is caused by venous hypertension resulting from retrograde flow due to incompetent venous valves, valve destruction, or obstruction of the venous system. Further tissue changes arise from an inflammatory process mediated by metalloproteinases, which are up-regulated by ferric ion from extravasated red blood cells. Stasis dermatitis presents initially as poorly demarcated erythematous plaques of the lower legs bilaterally, classically involving the medial malleolus. [{'predicate': 'subClassOf', 'target': 'Eczema'}]" }
{ "aliases": null, "definition": null, "id": "StaticOphthalmoparesis", "label": "Static ophthalmoparesis", "logical_definition": null, "original_id": "HP:0008507", "relationships": [ { "predicate": "subClassOf", "target": "Ophthalmoparesis" } ] }
0
{ "document": "Static ophthalmoparesis None [{'predicate': 'subClassOf', 'target': 'Ophthalmoparesis'}]" }
{ "aliases": null, "definition": "History of having taken statins, also known as HMG-CoA reductase inhibitors.", "id": "StatinExposure", "label": "Statin exposure", "logical_definition": null, "original_id": "HP:4000114", "relationships": [ { "predicate": "subClassOf", "target": "MedicationHistory" } ] }
0
{ "document": "Statin exposure History of having taken statins, also known as HMG-CoA reductase inhibitors. [{'predicate': 'subClassOf', 'target': 'MedicationHistory'}]" }
{ "aliases": null, "definition": "Severe asthma unresponsive to repeated courses of beta-agonist therapy such as inhaled albuterol, levalbuterol, or subcutaneous epinephrine.", "id": "StatusAsthmaticus", "label": "Status asthmaticus", "logical_definition": null, "original_id": "HP:0012653", "relationships": [ { "predicate": "subClassOf", "target": "Asthma" } ] }
0
{ "document": "Status asthmaticus Severe asthma unresponsive to repeated courses of beta-agonist therapy such as inhaled albuterol, levalbuterol, or subcutaneous epinephrine. [{'predicate': 'subClassOf', 'target': 'Asthma'}]" }
{ "aliases": null, "definition": "Diffusely widened perivascular spaces in the basal ganglia, affecting especially the corpus striatum. Status cribrosum is usually symmetrical, with the perivascular spaces showing CSF signal and without diffusion restriction. The word cribriform means sievelike, with multiple perforations.", "id": "StatusCribrosum", "label": "Status cribrosum", "logical_definition": null, "original_id": "HP:0025012", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBasalGangliaMorphology" } ] }
0
{ "document": "Status cribrosum Diffusely widened perivascular spaces in the basal ganglia, affecting especially the corpus striatum. Status cribrosum is usually symmetrical, with the perivascular spaces showing CSF signal and without diffusion restriction. The word cribriform means sievelike, with multiple perforations. [{'predicate': 'subClassOf', 'target': 'AbnormalBasalGangliaMorphology'}]" }
{ "aliases": null, "definition": "Status epilepticus is a type of prolonged seizure resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms which lead to abnormally prolonged seizures (after time point t1). It is a condition that can have long-term consequences (after time point t2), including neuronal death, neuronal injury, and alteration of neuronal networks, depending on the type and duration of seizures.", "id": "StatusEpilepticus", "label": "Status epilepticus", "logical_definition": null, "original_id": "HP:0002133", "relationships": [ { "predicate": "subClassOf", "target": "Seizure" } ] }
0
{ "document": "Status epilepticus Status epilepticus is a type of prolonged seizure resulting either from the failure of the mechanisms responsible for seizure termination or from the initiation of mechanisms which lead to abnormally prolonged seizures (after time point t1). It is a condition that can have long-term consequences (after time point t2), including neuronal death, neuronal injury, and alteration of neuronal networks, depending on the type and duration of seizures. [{'predicate': 'subClassOf', 'target': 'Seizure'}]" }
{ "aliases": null, "definition": "A type of focal motor status epilepticus characterized by prolonged ictal paresis or inhibitory motor seizures.", "id": "StatusEpilepticusWithIctalParesis", "label": "Status epilepticus with ictal paresis", "logical_definition": null, "original_id": "HP:0032862", "relationships": [ { "predicate": "subClassOf", "target": "FocalMotorStatusEpilepticus" } ] }
0
{ "document": "Status epilepticus with ictal paresis A type of focal motor status epilepticus characterized by prolonged ictal paresis or inhibitory motor seizures. [{'predicate': 'subClassOf', 'target': 'FocalMotorStatusEpilepticus'}]" }
{ "aliases": null, "definition": "Status epilepticus with prominent motor signs during the prolonged seizure.", "id": "StatusEpilepticusWithProminentMotorSymptoms", "label": "Status epilepticus with prominent motor symptoms", "logical_definition": null, "original_id": "HP:0032658", "relationships": [ { "predicate": "subClassOf", "target": "StatusEpilepticus" } ] }
0
{ "document": "Status epilepticus with prominent motor symptoms Status epilepticus with prominent motor signs during the prolonged seizure. [{'predicate': 'subClassOf', 'target': 'StatusEpilepticus'}]" }
{ "aliases": null, "definition": "There is inconclusive evidence to precisely define the duration of the seizure; however, based on current evidence an operational threshold of 10 minutes is appropriate as beyond this a seizure is likely to be more prolonged. The individual may or may not be aware or in coma.", "id": "StatusEpilepticusWithoutProminentMotorSymptoms", "label": "Status epilepticus without prominent motor symptoms", "logical_definition": null, "original_id": "HP:0031475", "relationships": [ { "predicate": "subClassOf", "target": "StatusEpilepticus" } ] }
0
{ "document": "Status epilepticus without prominent motor symptoms There is inconclusive evidence to precisely define the duration of the seizure; however, based on current evidence an operational threshold of 10 minutes is appropriate as beyond this a seizure is likely to be more prolonged. The individual may or may not be aware or in coma. [{'predicate': 'subClassOf', 'target': 'StatusEpilepticus'}]" }
{ "aliases": null, "definition": "The affected individual has received an organ transplant previous to the current medical encounter.", "id": "StatusPostOrganTransplantation", "label": "Status post organ transplantation", "logical_definition": null, "original_id": "HP:0032444", "relationships": [ { "predicate": "subClassOf", "target": "PastMedicalHistory" } ] }
0
{ "document": "Status post organ transplantation The affected individual has received an organ transplant previous to the current medical encounter. [{'predicate': 'subClassOf', 'target': 'PastMedicalHistory'}]" }
{ "aliases": null, "definition": "Multiple, localized or widespread, asymptomatic or inflammatory dermal cysts involving the pilosebaceous units. Lesions can appear anywhere on the body, but steatocystoma multiplex is more commonly involved with those areas of the skin with a high density of developed pilosebaceous units (e.g., the axilla, groin, neck, and proximal extremities).", "id": "SteatocystomaMultiplex", "label": "Steatocystoma multiplex", "logical_definition": null, "original_id": "HP:0012035", "relationships": [ { "predicate": "subClassOf", "target": "NeoplasmOfTheSkin" } ] }
0
{ "document": "Steatocystoma multiplex Multiple, localized or widespread, asymptomatic or inflammatory dermal cysts involving the pilosebaceous units. Lesions can appear anywhere on the body, but steatocystoma multiplex is more commonly involved with those areas of the skin with a high density of developed pilosebaceous units (e.g., the axilla, groin, neck, and proximal extremities). [{'predicate': 'subClassOf', 'target': 'NeoplasmOfTheSkin'}]" }
{ "aliases": null, "definition": "Greater than normal amounts of fat in the feces. This is a result of malabsorption of lipids in the small intestine and results in frothy foul-smelling fecal matter that floats.", "id": "Steatorrhea", "label": "Steatorrhea", "logical_definition": null, "original_id": "HP:0002570", "relationships": [ { "predicate": "subClassOf", "target": "FatMalabsorption" } ] }
0
{ "document": "Steatorrhea Greater than normal amounts of fat in the feces. This is a result of malabsorption of lipids in the small intestine and results in frothy foul-smelling fecal matter that floats. [{'predicate': 'subClassOf', 'target': 'FatMalabsorption'}]" }
{ "aliases": null, "definition": "Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells.", "id": "Steatosis", "label": "steatosis", "logical_definition": null, "original_id": "MPATH:622", "relationships": [ { "predicate": "subClassOf", "target": "IntracellularAndExtracellularAccumulation" } ] }
0
{ "document": "steatosis Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells. [{'predicate': 'subClassOf', 'target': 'IntracellularAndExtracellularAccumulation'}]" }
{ "aliases": null, "definition": "An exaggeration of the normal arched form of the acetabular roof such that it takes on a steep appearance.", "id": "SteepAcetabularRoof", "label": "Steep acetabular roof", "logical_definition": null, "original_id": "HP:0010455", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalAcetabulumMorphology" } ] }
0
{ "document": "Steep acetabular roof An exaggeration of the normal arched form of the acetabular roof such that it takes on a steep appearance. [{'predicate': 'subClassOf', 'target': 'AbnormalAcetabulumMorphology'}]" }
{ "aliases": null, "definition": "A lacy pattern or iris pigmentation that resembles the spokes of a bicycle wheel.", "id": "StellateIris", "label": "Stellate iris", "logical_definition": null, "original_id": "HP:0012775", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalIrisPigmentation" } ] }
0
{ "document": "Stellate iris A lacy pattern or iris pigmentation that resembles the spokes of a bicycle wheel. [{'predicate': 'subClassOf', 'target': 'AbnormalIrisPigmentation'}]" }
{ "aliases": null, "definition": "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.", "id": "StemCell", "label": "stem cell", "logical_definition": null, "original_id": "CL:0000034", "relationships": [ { "predicate": "CapableOf", "target": "CellDifferentiation" }, { "predicate": "subClassOf", "target": "AnimalCell" } ] }
0
{ "document": "stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [{'predicate': 'CapableOf', 'target': 'CellDifferentiation'}, {'predicate': 'subClassOf', 'target': 'AnimalCell'}]" }
{ "aliases": null, "definition": "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.", "id": "StemCellDivision", "label": "stem cell division", "logical_definition": null, "original_id": "GO:0017145", "relationships": [ { "predicate": "subClassOf", "target": "CellDivision" } ] }
0
{ "document": "stem cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. [{'predicate': 'subClassOf', 'target': 'CellDivision'}]" }
{ "aliases": null, "definition": "A somatic stem cell that is part of the epidermis.", "id": "StemCellOfEpidermis", "label": "stem cell of epidermis", "logical_definition": null, "original_id": "CL:1000428", "relationships": [ { "predicate": "subClassOf", "target": "SomaticStemCell" } ] }
0
{ "document": "stem cell of epidermis A somatic stem cell that is part of the epidermis. [{'predicate': 'subClassOf', 'target': 'SomaticStemCell'}]" }
{ "aliases": null, "definition": "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.", "id": "StemCellOfGastricGland", "label": "stem cell of gastric gland", "logical_definition": null, "original_id": "CL:0002183", "relationships": [ { "predicate": "subClassOf", "target": "MultiFateStemCell" }, { "predicate": "subClassOf", "target": "EpithelialCellOfStomach" } ] }
0
{ "document": "stem cell of gastric gland A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. [{'predicate': 'subClassOf', 'target': 'MultiFateStemCell'}, {'predicate': 'subClassOf', 'target': 'EpithelialCellOfStomach'}]" }
{ "aliases": null, "definition": null, "id": "StenosisOfTheEustachianTube", "label": "Stenosis of the Eustachian tube", "logical_definition": null, "original_id": "HP:0040118", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalEustachianTubeMorphology" } ] }
0
{ "document": "Stenosis of the Eustachian tube None [{'predicate': 'subClassOf', 'target': 'AbnormalEustachianTubeMorphology'}]" }
{ "aliases": null, "definition": "An abnormal narrowing of the external auditory canal.", "id": "StenosisOfTheExternalAuditoryCanal", "label": "Stenosis of the external auditory canal", "logical_definition": null, "original_id": "HP:0000402", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTheAuditoryCanal" } ] }
0
{ "document": "Stenosis of the external auditory canal An abnormal narrowing of the external auditory canal. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheAuditoryCanal'}]" }
{ "aliases": null, "definition": null, "id": "StenosisOfTheMedullaryCavityOfTheLongBones", "label": "Stenosis of the medullary cavity of the long bones", "logical_definition": null, "original_id": "HP:0100254", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfTheMedullaryCavityOfTheLongBones" } ] }
0
{ "document": "Stenosis of the medullary cavity of the long bones None [{'predicate': 'subClassOf', 'target': 'AbnormalityOfTheMedullaryCavityOfTheLongBones'}]" }
{ "aliases": null, "definition": "An abnormal gait pattern that arises from weakness of the pretibial and peroneal muscles due to a lower motor neuron lesion. Affected patients have footdrop and are unable to dorsiflex and evert the foot. The leg is lifted high on walking so that the toes clear the ground, and there may be a slapping noise when the foot strikes the ground again.", "id": "SteppageGait", "label": "Steppage gait", "logical_definition": null, "original_id": "HP:0003376", "relationships": [ { "predicate": "subClassOf", "target": "GaitDisturbance" } ] }
0
{ "document": "Steppage gait An abnormal gait pattern that arises from weakness of the pretibial and peroneal muscles due to a lower motor neuron lesion. Affected patients have footdrop and are unable to dorsiflex and evert the foot. The leg is lifted high on walking so that the toes clear the ground, and there may be a slapping noise when the foot strikes the ground again. [{'predicate': 'subClassOf', 'target': 'GaitDisturbance'}]" }
{ "aliases": null, "definition": "An ulcer of the colon due to pressure and irritation from retained fecal masses.", "id": "StercoralUlcer", "label": "Stercoral ulcer", "logical_definition": null, "original_id": "HP:0012425", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalLargeIntestineMorphology" }, { "predicate": "subClassOf", "target": "GastrointestinalUlcer" } ] }
0
{ "document": "Stercoral ulcer An ulcer of the colon due to pressure and irritation from retained fecal masses. [{'predicate': 'subClassOf', 'target': 'AbnormalLargeIntestineMorphology'}, {'predicate': 'subClassOf', 'target': 'GastrointestinalUlcer'}]" }
{ "aliases": null, "definition": "A pathological behavior associated with repetitive or ritualistic movement, posture, or utterance.", "id": "StereotypicBehavior", "label": "stereotypic behavior", "logical_definition": null, "original_id": "NBO:0000567", "relationships": [ { "predicate": "subClassOf", "target": "VoluntaryMovementBehaviorPhenotype" } ] }
0
{ "document": "stereotypic behavior A pathological behavior associated with repetitive or ritualistic movement, posture, or utterance. [{'predicate': 'subClassOf', 'target': 'VoluntaryMovementBehaviorPhenotype'}]" }
{ "aliases": null, "definition": "Habitual repetitive movement of the entire body, front to back or side to side.", "id": "StereotypicalBodyRocking", "label": "Stereotypical body rocking", "logical_definition": null, "original_id": "HP:0012172", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalMovementsOfTheWholeBody" } ] }
0
{ "document": "Stereotypical body rocking Habitual repetitive movement of the entire body, front to back or side to side. [{'predicate': 'subClassOf', 'target': 'AbnormalMovementsOfTheWholeBody'}]" }
{ "aliases": null, "definition": "Habitual clasping and wringing of the hands in the middle of the body, similar to a hand-washing movement.", "id": "StereotypicalHandWringing", "label": "Stereotypical hand wringing", "logical_definition": null, "original_id": "HP:0012171", "relationships": [ { "predicate": "subClassOf", "target": "MidlineHandMovements" } ] }
0
{ "document": "Stereotypical hand wringing Habitual clasping and wringing of the hands in the middle of the body, similar to a hand-washing movement. [{'predicate': 'subClassOf', 'target': 'MidlineHandMovements'}]" }
{ "aliases": null, "definition": "A fertility quality inhering in a bearer by virtue of the bearer's being incapable of initiating, sustaining, or supporting reproduction.", "id": "Sterile", "label": "sterile", "logical_definition": null, "original_id": "PATO:0000956", "relationships": [ { "predicate": "subClassOf", "target": "Fertility" } ] }
0
{ "document": "sterile A fertility quality inhering in a bearer by virtue of the bearer's being incapable of initiating, sustaining, or supporting reproduction. [{'predicate': 'subClassOf', 'target': 'Fertility'}]" }
{ "aliases": null, "definition": "An abscess not caused by infection with pyogenic bacteria. Operationally, a sterile abscess is inferred if investigations of an abscess fail to reveal evidence of pathogenic organisms.", "id": "SterileAbscess", "label": "Sterile abscess", "logical_definition": null, "original_id": "HP:0025616", "relationships": [ { "predicate": "subClassOf", "target": "Abscess" } ] }
0
{ "document": "Sterile abscess An abscess not caused by infection with pyogenic bacteria. Operationally, a sterile abscess is inferred if investigations of an abscess fail to reveal evidence of pathogenic organisms. [{'predicate': 'subClassOf', 'target': 'Abscess'}]" }
{ "aliases": null, "definition": "An inflammatory arthritis characterized by purulent synovial fluid with neutrophil accumulation, but with negative cultures.", "id": "SterileArthritis", "label": "Sterile arthritis", "logical_definition": null, "original_id": "HP:0040310", "relationships": [ { "predicate": "subClassOf", "target": "Arthritis" } ] }
0
{ "document": "Sterile arthritis An inflammatory arthritis characterized by purulent synovial fluid with neutrophil accumulation, but with negative cultures. [{'predicate': 'subClassOf', 'target': 'Arthritis'}]" }
{ "aliases": null, "definition": "Patients who routinely have greater than 20 leukocytes per microliter, but have abacterial urine, are said to have sterile pyuria.", "id": "SterilePyuria", "label": "Sterile pyuria", "logical_definition": null, "original_id": "HP:0100586", "relationships": [ { "predicate": "subClassOf", "target": "Pyuria" } ] }
0
{ "document": "Sterile pyuria Patients who routinely have greater than 20 leukocytes per microliter, but have abacterial urine, are said to have sterile pyuria. [{'predicate': 'subClassOf', 'target': 'Pyuria'}]" }
{ "aliases": null, "definition": "Medial end of the clavicle, which usually lies on the ventral side of the epicoracoid cartilage, just posterior to the epicoracoid bridge.", "id": "SternalEndOfClavicle", "label": "sternal end of clavicle", "logical_definition": null, "original_id": "UBERON:0006805", "relationships": [ { "predicate": "PartOf", "target": "ClavicleBone" }, { "predicate": "subClassOf", "target": "ZoneOfBoneOrgan" } ] }
0
{ "document": "sternal end of clavicle Medial end of the clavicle, which usually lies on the ventral side of the epicoracoid cartilage, just posterior to the epicoracoid bridge. [{'predicate': 'PartOf', 'target': 'ClavicleBone'}, {'predicate': 'subClassOf', 'target': 'ZoneOfBoneOrgan'}]" }
{ "aliases": null, "definition": "A sternal pit is a small indentation or dimple in the skin overlying the sternum of the chest. In some cases, the skin defect can be linear, extending several inches over the sternum.", "id": "SternalPit", "label": "Sternal pit", "logical_definition": null, "original_id": "HP:0410277", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSternumMorphology" } ] }
0
{ "document": "Sternal pit A sternal pit is a small indentation or dimple in the skin overlying the sternum of the chest. In some cases, the skin defect can be linear, extending several inches over the sternum. [{'predicate': 'subClassOf', 'target': 'AbnormalSternumMorphology'}]" }
{ "aliases": null, "definition": null, "id": "SternalPunctateCalcifications", "label": "Sternal punctate calcifications", "logical_definition": null, "original_id": "HP:0006637", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSternumMorphology" }, { "predicate": "subClassOf", "target": "EctopicCalcification" } ] }
0
{ "document": "Sternal punctate calcifications None [{'predicate': 'subClassOf', 'target': 'AbnormalSternumMorphology'}, {'predicate': 'subClassOf', 'target': 'EctopicCalcification'}]" }
{ "aliases": null, "definition": "One of the bony segments of the sternum[TFD].", "id": "Sternebra", "label": "sternebra", "logical_definition": null, "original_id": "UBERON:0002208", "relationships": [ { "predicate": "PartOf", "target": "Sternum" }, { "predicate": "DevelopsFrom", "target": "SternebralBonePreCartilageCondensation" }, { "predicate": "subClassOf", "target": "EndochondralBone" } ] }
0
{ "document": "sternebra One of the bony segments of the sternum[TFD]. [{'predicate': 'PartOf', 'target': 'Sternum'}, {'predicate': 'DevelopsFrom', 'target': 'SternebralBonePreCartilageCondensation'}, {'predicate': 'subClassOf', 'target': 'EndochondralBone'}]" }
{ "aliases": null, "definition": null, "id": "SternebralBonePreCartilageCondensation", "label": "sternebral bone pre-cartilage condensation", "logical_definition": null, "original_id": "UBERON:0006295", "relationships": [ { "predicate": "PartOf", "target": "Sternum" }, { "predicate": "DevelopsFrom", "target": "BodyWallMesenchyme" }, { "predicate": "subClassOf", "target": "PreCartilageCondensation" } ] }
0
{ "document": "sternebral bone pre-cartilage condensation None [{'predicate': 'PartOf', 'target': 'Sternum'}, {'predicate': 'DevelopsFrom', 'target': 'BodyWallMesenchyme'}, {'predicate': 'subClassOf', 'target': 'PreCartilageCondensation'}]" }
{ "aliases": null, "definition": "The sternocephalicus is a flat muscle and its caudal border is adjacent to the ventral border of the brachiocephalicus. The lateral aspect of this muscle is crossed obliquely by the external jugular vein. It originates as a unit on the first sternebrae. The cranial portion of the muscle divides into two separate sections with different insertion points. These are the sternomastoideus and the sterno-occipitalis. The ventral portion, the sternomastiodeus is the stronger and main continuation of the sternocephalicus, which inserts on the mastoid part of the temporal bone. The thin but wide dorsal segment, the sterno-occipitalis attaches to the dorsal nuchal crest by a thin aponeurosis. The main action provided by the sternocephalicus is movement of the head and neck to the side. Ventral branches of the cervical nerves are attached to this muscle.", "id": "SternocephalicusMuscle", "label": "sternocephalicus muscle", "logical_definition": null, "original_id": "UBERON:0011371", "relationships": [ { "predicate": "HasMuscleInsertion", "target": "OccipitalBone" } ] }
0
{ "document": "sternocephalicus muscle The sternocephalicus is a flat muscle and its caudal border is adjacent to the ventral border of the brachiocephalicus. The lateral aspect of this muscle is crossed obliquely by the external jugular vein. It originates as a unit on the first sternebrae. The cranial portion of the muscle divides into two separate sections with different insertion points. These are the sternomastoideus and the sterno-occipitalis. The ventral portion, the sternomastiodeus is the stronger and main continuation of the sternocephalicus, which inserts on the mastoid part of the temporal bone. The thin but wide dorsal segment, the sterno-occipitalis attaches to the dorsal nuchal crest by a thin aponeurosis. The main action provided by the sternocephalicus is movement of the head and neck to the side. Ventral branches of the cervical nerves are attached to this muscle. [{'predicate': 'HasMuscleInsertion', 'target': 'OccipitalBone'}]" }
{ "aliases": null, "definition": "The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted].", "id": "SternoclavicularJoint", "label": "sternoclavicular joint", "logical_definition": null, "original_id": "UBERON:0001469", "relationships": [ { "predicate": "Connects", "target": "Sternum" }, { "predicate": "Connects", "target": "ClavicleBone" }, { "predicate": "subClassOf", "target": "SynovialJointOfPectoralGirdle" } ] }
0
{ "document": "sternoclavicular joint The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]. [{'predicate': 'Connects', 'target': 'Sternum'}, {'predicate': 'Connects', 'target': 'ClavicleBone'}, {'predicate': 'subClassOf', 'target': 'SynovialJointOfPectoralGirdle'}]" }
{ "aliases": null, "definition": "Wasting of the sternocleidomastoid muscle, the muscle in the anterior part of the neck that acts to flex and rotate the head.", "id": "SternocleidomastoidAmyotrophy", "label": "Sternocleidomastoid amyotrophy", "logical_definition": null, "original_id": "HP:0012036", "relationships": [ { "predicate": "subClassOf", "target": "SkeletalMuscleAtrophy" } ] }
0
{ "document": "Sternocleidomastoid amyotrophy Wasting of the sternocleidomastoid muscle, the muscle in the anterior part of the neck that acts to flex and rotate the head. [{'predicate': 'subClassOf', 'target': 'SkeletalMuscleAtrophy'}]" }
{ "aliases": null, "definition": "A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum.", "id": "SternooccipitalMuscle", "label": "sternooccipital muscle", "logical_definition": null, "original_id": "UBERON:0010949", "relationships": [ { "predicate": "subClassOf", "target": "MuscleOfNeck" } ] }
0
{ "document": "sternooccipital muscle A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum. [{'predicate': 'subClassOf', 'target': 'MuscleOfNeck'}]" }
{ "aliases": null, "definition": "A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad].", "id": "Sternum", "label": "sternum", "logical_definition": null, "original_id": "UBERON:0000975", "relationships": [ { "predicate": "PartOf", "target": "ThoracicSegmentOfTrunk" }, { "predicate": "PartOf", "target": "ThoracicRibCage" }, { "predicate": "ConnectedTo", "target": "Rib" }, { "predicate": "ConnectedTo", "target": "PectoralGirdleSkeleton" }, { "predicate": "ContributesToMorphologyOf", "target": "ThoracicRibCage" }, { "predicate": "subClassOf", "target": "EndochondralElement" } ] }
0
{ "document": "sternum A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]. [{'predicate': 'PartOf', 'target': 'ThoracicSegmentOfTrunk'}, {'predicate': 'PartOf', 'target': 'ThoracicRibCage'}, {'predicate': 'ConnectedTo', 'target': 'Rib'}, {'predicate': 'ConnectedTo', 'target': 'PectoralGirdleSkeleton'}, {'predicate': 'ContributesToMorphologyOf', 'target': 'ThoracicRibCage'}, {'predicate': 'subClassOf', 'target': 'EndochondralElement'}]" }
{ "aliases": null, "definition": "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.", "id": "Steroid", "label": "steroid", "logical_definition": null, "original_id": "CHEBI:35341", "relationships": [ { "predicate": "subClassOf", "target": "Lipid" }, { "predicate": "subClassOf", "target": "OrganicPolycyclicCompound" } ] }
0
{ "document": "steroid Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. [{'predicate': 'subClassOf', 'target': 'Lipid'}, {'predicate': 'subClassOf', 'target': 'OrganicPolycyclicCompound'}]" }
{ "aliases": null, "definition": "Any steroid substituted by at least one carboxy group.", "id": "SteroidAcid", "label": "steroid acid", "logical_definition": null, "original_id": "CHEBI:47891", "relationships": [ { "predicate": "obo:chebi#is_conjugate_acid_of", "target": "SteroidAcidAnion" }, { "predicate": "subClassOf", "target": "Steroid" }, { "predicate": "subClassOf", "target": "OrganicAcid" } ] }
0
{ "document": "steroid acid Any steroid substituted by at least one carboxy group. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': 'SteroidAcidAnion'}, {'predicate': 'subClassOf', 'target': 'Steroid'}, {'predicate': 'subClassOf', 'target': 'OrganicAcid'}]" }
{ "aliases": null, "definition": "Any anion formed by loss of a proton from a steroid acid.", "id": "SteroidAcidAnion", "label": "steroid acid anion", "logical_definition": null, "original_id": "CHEBI:50160", "relationships": [ { "predicate": "obo:chebi#is_conjugate_base_of", "target": "SteroidAcid" }, { "predicate": "subClassOf", "target": "CarboxylicAcidAnion" } ] }
0
{ "document": "steroid acid anion Any anion formed by loss of a proton from a steroid acid. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'SteroidAcid'}, {'predicate': 'subClassOf', 'target': 'CarboxylicAcidAnion'}]" }
{ "aliases": null, "definition": "Any steroid substituted by a formyl group.", "id": "SteroidAldehyde", "label": "steroid aldehyde", "logical_definition": null, "original_id": "CHEBI:131565", "relationships": [ { "predicate": "subClassOf", "target": "Aldehyde" }, { "predicate": "subClassOf", "target": "Steroid" } ] }
0
{ "document": "steroid aldehyde Any steroid substituted by a formyl group. [{'predicate': 'subClassOf', 'target': 'Aldehyde'}, {'predicate': 'subClassOf', 'target': 'Steroid'}]" }
{ "aliases": null, "definition": "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.", "id": "SteroidBiosyntheticProcess", "label": "steroid biosynthetic process", "logical_definition": null, "original_id": "GO:0006694", "relationships": [ { "predicate": "subClassOf", "target": "SteroidMetabolicProcess" }, { "predicate": "subClassOf", "target": "LipidBiosyntheticProcess" }, { "predicate": "subClassOf", "target": "OrganicCyclicCompoundBiosyntheticProcess" } ] }
0
{ "document": "steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. [{'predicate': 'subClassOf', 'target': 'SteroidMetabolicProcess'}, {'predicate': 'subClassOf', 'target': 'LipidBiosyntheticProcess'}, {'predicate': 'subClassOf', 'target': 'OrganicCyclicCompoundBiosyntheticProcess'}]" }
{ "aliases": null, "definition": "A type of nephrotic syndrome in which two consecutive relapses (albumin urine dipstick at least 3+ or proteinuria greater than 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) occur during corticosteroid therapy, or within 14 days of ceasing therapy.", "id": "SteroidDependentNephroticSyndrome", "label": "Steroid-dependent nephrotic syndrome", "logical_definition": null, "original_id": "HP:0025650", "relationships": [ { "predicate": "subClassOf", "target": "NephroticSyndrome" } ] }
0
{ "document": "Steroid-dependent nephrotic syndrome A type of nephrotic syndrome in which two consecutive relapses (albumin urine dipstick at least 3+ or proteinuria greater than 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) occur during corticosteroid therapy, or within 14 days of ceasing therapy. [{'predicate': 'subClassOf', 'target': 'NephroticSyndrome'}]" }
{ "aliases": null, "definition": null, "id": "SteroidEster", "label": "steroid ester", "logical_definition": null, "original_id": "CHEBI:47880", "relationships": [ { "predicate": "subClassOf", "target": "Steroid" }, { "predicate": "subClassOf", "target": "Ester" } ] }
0
{ "document": "steroid ester None [{'predicate': 'subClassOf', 'target': 'Steroid'}, {'predicate': 'subClassOf', 'target': 'Ester'}]" }
{ "aliases": null, "definition": null, "id": "SteroidFundamentalParent", "label": "steroid fundamental parent", "logical_definition": null, "original_id": "CHEBI:35508", "relationships": [ { "predicate": "subClassOf", "target": "Steroid" }, { "predicate": "subClassOf", "target": "NaturalProductFundamentalParent" } ] }
0
{ "document": "steroid fundamental parent None [{'predicate': 'subClassOf', 'target': 'Steroid'}, {'predicate': 'subClassOf', 'target': 'NaturalProductFundamentalParent'}]" }
{ "aliases": null, "definition": "Any steroid that acts as hormone.", "id": "SteroidHormone", "label": "steroid hormone", "logical_definition": null, "original_id": "CHEBI:26764", "relationships": [ { "predicate": "HasRole", "target": "Hormone" }, { "predicate": "subClassOf", "target": "Steroid" } ] }
0
{ "document": "steroid hormone Any steroid that acts as hormone. [{'predicate': 'HasRole', 'target': 'Hormone'}, {'predicate': 'subClassOf', 'target': 'Steroid'}]" }
{ "aliases": null, "definition": "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.", "id": "SteroidHormoneBiosyntheticProcess", "label": "steroid hormone biosynthetic process", "logical_definition": null, "original_id": "GO:0120178", "relationships": [ { "predicate": "subClassOf", "target": "SteroidBiosyntheticProcess" } ] }
0
{ "document": "steroid hormone biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. [{'predicate': 'subClassOf', 'target': 'SteroidBiosyntheticProcess'}]" }
{ "aliases": null, "definition": null, "id": "SteroidHormoneSecretingCell", "label": "steroid hormone secreting cell", "logical_definition": null, "original_id": "CL:0000174", "relationships": null }
0
{ "document": "steroid hormone secreting cell None None" }
{ "aliases": null, "definition": "The regulated release of any steroid that acts as a hormone into the circulatory system.", "id": "SteroidHormoneSecretion", "label": "steroid hormone secretion", "logical_definition": null, "original_id": "GO:0035929", "relationships": [ { "predicate": "subClassOf", "target": "EndocrineHormoneSecretion" }, { "predicate": "subClassOf", "target": "LipidExportFromCell" } ] }
0
{ "document": "steroid hormone secretion The regulated release of any steroid that acts as a hormone into the circulatory system. [{'predicate': 'subClassOf', 'target': 'EndocrineHormoneSecretion'}, {'predicate': 'subClassOf', 'target': 'LipidExportFromCell'}]" }