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{ "aliases": null, "definition": "The presence of a neoplasm of the urinary bladder.", "id": "BladderNeoplasm", "label": "Bladder neoplasm", "logical_definition": null, "original_id": "HP:0009725", "relationships": [ { "predicate": "subClassOf", "target": "UrinaryTractNeoplasm" } ] }
0
{ "document": "Bladder neoplasm The presence of a neoplasm of the urinary bladder. [{'predicate': 'subClassOf', 'target': 'UrinaryTractNeoplasm'}]" }
{ "aliases": null, "definition": "A membranous sac in animals that serves as the receptacle of a liquid or contains gas.", "id": "BladderOrgan", "label": "bladder organ", "logical_definition": null, "original_id": "UBERON:0018707", "relationships": [ { "predicate": "HasQuality", "target": "Saccular" }, { "predicate": "HasQuality", "target": "Distensible" }, { "predicate": "LocationOf", "target": "OrganismSubstance" }, { "predicate": "subClassOf", "target": "CavitatedCompoundOrgan" } ] }
0
{ "document": "bladder organ A membranous sac in animals that serves as the receptacle of a liquid or contains gas. [{'predicate': 'HasQuality', 'target': 'Saccular'}, {'predicate': 'HasQuality', 'target': 'Distensible'}, {'predicate': 'LocationOf', 'target': 'OrganismSubstance'}, {'predicate': 'subClassOf', 'target': 'CavitatedCompoundOrgan'}]" }
{ "aliases": null, "definition": "A compression or resistance upon the bladder outflow channel at any location from the bladder neck to urethral meatus, which usually causes lower urinary tract symptoms (LUTS).", "id": "BladderOutletObstruction", "label": "Bladder outlet obstruction", "logical_definition": null, "original_id": "HP:0041047", "relationships": [ { "predicate": "subClassOf", "target": "FunctionalAbnormalityOfTheBladder" } ] }
0
{ "document": "Bladder outlet obstruction A compression or resistance upon the bladder outflow channel at any location from the bladder neck to urethral meatus, which usually causes lower urinary tract symptoms (LUTS). [{'predicate': 'subClassOf', 'target': 'FunctionalAbnormalityOfTheBladder'}]" }
{ "aliases": null, "definition": "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the urinary bladder. Bladder pain may be more pronounced with a full bladder and relieved upon urination, but this is not always the case.", "id": "BladderPain", "label": "Bladder pain", "logical_definition": null, "original_id": "HP:0032171", "relationships": [ { "predicate": "subClassOf", "target": "Pain" } ] }
0
{ "document": "Bladder pain An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the urinary bladder. Bladder pain may be more pronounced with a full bladder and relieved upon urination, but this is not always the case. [{'predicate': 'subClassOf', 'target': 'Pain'}]" }
{ "aliases": null, "definition": "An abnormal growth that projects from the mucous membrane of the urinary bladder.", "id": "BladderPolyp", "label": "Bladder polyp", "logical_definition": null, "original_id": "HP:0031261", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfBladderMorphology" } ] }
0
{ "document": "Bladder polyp An abnormal growth that projects from the mucous membrane of the urinary bladder. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfBladderMorphology'}]" }
{ "aliases": null, "definition": "Buildups of minerals that form in the urinary bladder.", "id": "BladderStones", "label": "Bladder stones", "logical_definition": null, "original_id": "HP:0010474", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfBladderMorphology" } ] }
0
{ "document": "Bladder stones Buildups of minerals that form in the urinary bladder. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfBladderMorphology'}]" }
{ "aliases": null, "definition": "Muscular projections that protrude into the lumen of the bladder, criss-crossing the walls of the bladder on its inner surface.", "id": "BladderTrabeculation", "label": "Bladder trabeculation", "logical_definition": null, "original_id": "HP:0032465", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfBladderMorphology" } ] }
0
{ "document": "Bladder trabeculation Muscular projections that protrude into the lumen of the bladder, criss-crossing the walls of the bladder on its inner surface. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfBladderMorphology'}]" }
{ "aliases": null, "definition": "The presence of an upwardly displaced normal cerebellar vermis, normal appearance of the fastigium, tentorium and size of the cisterna magna.", "id": "BlakeSPouchCyst", "label": "Blake's pouch cyst", "logical_definition": null, "original_id": "HP:0033140", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalPosteriorCranialFossaMorphology" } ] }
0
{ "document": "Blake's pouch cyst The presence of an upwardly displaced normal cerebellar vermis, normal appearance of the fastigium, tentorium and size of the cisterna magna. [{'predicate': 'subClassOf', 'target': 'AbnormalPosteriorCranialFossaMorphology'}]" }
{ "aliases": null, "definition": null, "id": "BlastemalCell", "label": "blastemal cell", "logical_definition": null, "original_id": "CL:0000354", "relationships": [ { "predicate": "subClassOf", "target": "MultiFateStemCell" } ] }
0
{ "document": "blastemal cell None [{'predicate': 'subClassOf', 'target': 'MultiFateStemCell'}]" }
{ "aliases": null, "definition": "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO].", "id": "Blastocyst", "label": "blastocyst", "logical_definition": null, "original_id": "UBERON:0000358", "relationships": [ { "predicate": "PartOf", "target": "Blastula" }, { "predicate": "HasPart", "target": "InnerCellMass" }, { "predicate": "HasPart", "target": "Trophoblast" }, { "predicate": "DevelopsFrom", "target": "Morula" }, { "predicate": "ExistenceStartsAndEndsDuring", "target": "BlastulaStage" }, { "predicate": "subClassOf", "target": "EmbryonicStructure" } ] }
0
{ "document": "blastocyst The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. [{'predicate': 'PartOf', 'target': 'Blastula'}, {'predicate': 'HasPart', 'target': 'InnerCellMass'}, {'predicate': 'HasPart', 'target': 'Trophoblast'}, {'predicate': 'DevelopsFrom', 'target': 'Morula'}, {'predicate': 'ExistenceStartsAndEndsDuring', 'target': 'BlastulaStage'}, {'predicate': 'subClassOf', 'target': 'EmbryonicStructure'}]" }
{ "aliases": null, "definition": "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote).", "id": "BlastodermCell", "label": "blastoderm cell", "logical_definition": null, "original_id": "CL:0000353", "relationships": [ { "predicate": "subClassOf", "target": "EarlyEmbryonicCell_metazoa_" } ] }
0
{ "document": "blastoderm cell An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). [{'predicate': 'subClassOf', 'target': 'EarlyEmbryonicCell_metazoa_'}]" }
{ "aliases": null, "definition": "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence.", "id": "Blastula", "label": "blastula", "logical_definition": null, "original_id": "UBERON:0000307", "relationships": [ { "predicate": "DevelopsFrom", "target": "CleavingEmbryo" }, { "predicate": "subClassOf", "target": "Embryo" } ] }
0
{ "document": "blastula Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. [{'predicate': 'DevelopsFrom', 'target': 'CleavingEmbryo'}, {'predicate': 'subClassOf', 'target': 'Embryo'}]" }
{ "aliases": null, "definition": "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence.", "id": "BlastulaStage", "label": "blastula stage", "logical_definition": null, "original_id": "UBERON:0000108", "relationships": [ { "predicate": "PartOf", "target": "EmbryoStage" }, { "predicate": "PrecededBy", "target": "CleavageStage" }, { "predicate": "subClassOf", "target": "LifeCycleStage" } ] }
0
{ "document": "blastula stage An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. [{'predicate': 'PartOf', 'target': 'EmbryoStage'}, {'predicate': 'PrecededBy', 'target': 'CleavageStage'}, {'predicate': 'subClassOf', 'target': 'LifeCycleStage'}]" }
{ "aliases": null, "definition": "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.", "id": "BlebAssembly", "label": "bleb assembly", "logical_definition": null, "original_id": "GO:0032060", "relationships": [ { "predicate": "subClassOf", "target": "PlasmaMembraneBoundedCellProjectionAssembly" } ] }
0
{ "document": "bleb assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. [{'predicate': 'subClassOf', 'target': 'PlasmaMembraneBoundedCellProjectionAssembly'}]" }
{ "aliases": null, "definition": "Tubular cross section with round/irregular cytoplasmic protrusion, shaped like the Greek capital letter Omega (or it may be more vertically elongated Omega), pinched off from apical membrane without apparent closure of the lumen, involving over 50 percent of the tubular cells in cross section. The feature can be further classified into proximal or distal tubule.", "id": "BlebbingOfApicalCytoplasmOfRenalTubularEpithelialCells", "label": "Blebbing of apical cytoplasm of renal tubular epithelial cells", "logical_definition": null, "original_id": "HP:0032598", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalRenalTubularEpithelialMorphology" } ] }
0
{ "document": "Blebbing of apical cytoplasm of renal tubular epithelial cells Tubular cross section with round/irregular cytoplasmic protrusion, shaped like the Greek capital letter Omega (or it may be more vertically elongated Omega), pinched off from apical membrane without apparent closure of the lumen, involving over 50 percent of the tubular cells in cross section. The feature can be further classified into proximal or distal tubule. [{'predicate': 'subClassOf', 'target': 'AbnormalRenalTubularEpithelialMorphology'}]" }
{ "aliases": null, "definition": "Applies to bleeding that is significantly reduced by treatment with vitamin K.", "id": "BleedingAmelioratedByVitaminK", "label": "Bleeding ameliorated by vitamin K", "logical_definition": null, "original_id": "HP:4000177", "relationships": [ { "predicate": "subClassOf", "target": "AmelioratedByExposureToMedication" } ] }
0
{ "document": "Bleeding ameliorated by vitamin K Applies to bleeding that is significantly reduced by treatment with vitamin K. [{'predicate': 'subClassOf', 'target': 'AmelioratedByExposureToMedication'}]" }
{ "aliases": null, "definition": "Bleeding sufficiently severe as to require red cell transfusion (WHO Grade 3 or 4).", "id": "BleedingRequiringRedCellTransfusion", "label": "Bleeding requiring red cell transfusion", "logical_definition": null, "original_id": "HP:0011888", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBleeding" } ] }
0
{ "document": "Bleeding requiring red cell transfusion Bleeding sufficiently severe as to require red cell transfusion (WHO Grade 3 or 4). [{'predicate': 'subClassOf', 'target': 'AbnormalBleeding'}]" }
{ "aliases": null, "definition": "Significant bleeding or hemorrhage without significant precipitating factor.", "id": "BleedingWithMinorOrNoTrauma", "label": "Bleeding with minor or no trauma", "logical_definition": null, "original_id": "HP:0011889", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBleeding" } ] }
0
{ "document": "Bleeding with minor or no trauma Significant bleeding or hemorrhage without significant precipitating factor. [{'predicate': 'subClassOf', 'target': 'AbnormalBleeding'}]" }
{ "aliases": null, "definition": "Inflammation of the eyelids.", "id": "Blepharitis", "label": "Blepharitis", "logical_definition": null, "original_id": "HP:0000498", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalEyelidMorphology" }, { "predicate": "subClassOf", "target": "InflammatoryAbnormalityOfTheEye" } ] }
0
{ "document": "Blepharitis Inflammation of the eyelids. [{'predicate': 'subClassOf', 'target': 'AbnormalEyelidMorphology'}, {'predicate': 'subClassOf', 'target': 'InflammatoryAbnormalityOfTheEye'}]" }
{ "aliases": null, "definition": "Blepharochalasis is characterized by recurrent, non-painful, nonerythematous episodes of eyelid edema. It has been divided into hypertrophic and atrophic forms. In the hypertrophic form recurrent edema results in orbital fat herniation through a weakened orbital septum. Most patients who have blepharochalasis present in an atrophic condition with atrophy of redundant eyelid skin and superior nasal fat pads.", "id": "Blepharochalasis", "label": "Blepharochalasis", "logical_definition": null, "original_id": "HP:0010749", "relationships": [ { "predicate": "subClassOf", "target": "PalpebralEdema" } ] }
0
{ "document": "Blepharochalasis Blepharochalasis is characterized by recurrent, non-painful, nonerythematous episodes of eyelid edema. It has been divided into hypertrophic and atrophic forms. In the hypertrophic form recurrent edema results in orbital fat herniation through a weakened orbital septum. Most patients who have blepharochalasis present in an atrophic condition with atrophy of redundant eyelid skin and superior nasal fat pads. [{'predicate': 'subClassOf', 'target': 'PalpebralEdema'}]" }
{ "aliases": null, "definition": "A fixed reduction in the vertical distance between the upper and lower eyelids with short palpebral fissures.", "id": "Blepharophimosis", "label": "Blepharophimosis", "logical_definition": null, "original_id": "HP:0000581", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSizeOfThePalpebralFissures" } ] }
0
{ "document": "Blepharophimosis A fixed reduction in the vertical distance between the upper and lower eyelids with short palpebral fissures. [{'predicate': 'subClassOf', 'target': 'AbnormalSizeOfThePalpebralFissures'}]" }
{ "aliases": null, "definition": "A focal dystonia that affects the muscles of the eyelids and brow, associated with involuntary recurrent spasm of both eyelids.", "id": "Blepharospasm", "label": "Blepharospasm", "logical_definition": null, "original_id": "HP:0000643", "relationships": [ { "predicate": "subClassOf", "target": "CraniofacialDystonia" }, { "predicate": "subClassOf", "target": "AbnormalEyelidPhysiology" } ] }
0
{ "document": "Blepharospasm A focal dystonia that affects the muscles of the eyelids and brow, associated with involuntary recurrent spasm of both eyelids. [{'predicate': 'subClassOf', 'target': 'CraniofacialDystonia'}, {'predicate': 'subClassOf', 'target': 'AbnormalEyelidPhysiology'}]" }
{ "aliases": null, "definition": null, "id": "BlindSpotEnlargment", "label": "Blind-spot enlargment", "logical_definition": null, "original_id": "HP:0030644", "relationships": [ { "predicate": "subClassOf", "target": "VisualFieldDefect" } ] }
0
{ "document": "Blind-spot enlargment None [{'predicate': 'subClassOf', 'target': 'VisualFieldDefect'}]" }
{ "aliases": null, "definition": "The vagina ends in a blind pouch or sac rather than being connected to the internal genitalia.", "id": "BlindVagina", "label": "Blind vagina", "logical_definition": null, "original_id": "HP:0040314", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalVaginaMorphology" } ] }
0
{ "document": "Blind vagina The vagina ends in a blind pouch or sac rather than being connected to the internal genitalia. [{'predicate': 'subClassOf', 'target': 'AbnormalVaginaMorphology'}]" }
{ "aliases": null, "definition": "Blindness is the condition of lacking visual perception defined as visual perception below 3/60 and/or a visual field of no greater than 10 degrees in radius around central fixation.", "id": "Blindness", "label": "Blindness", "logical_definition": null, "original_id": "HP:0000618", "relationships": [ { "predicate": "subClassOf", "target": "ReducedVisualAcuity" } ] }
0
{ "document": "Blindness Blindness is the condition of lacking visual perception defined as visual perception below 3/60 and/or a visual field of no greater than 10 degrees in radius around central fixation. [{'predicate': 'subClassOf', 'target': 'ReducedVisualAcuity'}]" }
{ "aliases": null, "definition": "A texture quality inhering in a bearer by virtue of a local accumulation of fluid underneath the surface of the bearer.", "id": "Blistered", "label": "blistered", "logical_definition": null, "original_id": "PATO:0001928", "relationships": [ { "predicate": "subClassOf", "target": "Texture" } ] }
0
{ "document": "blistered A texture quality inhering in a bearer by virtue of a local accumulation of fluid underneath the surface of the bearer. [{'predicate': 'subClassOf', 'target': 'Texture'}]" }
{ "aliases": null, "definition": "Blistering (presence of multiple fluid filled blisters) categorized according to the body site where they occur.", "id": "BlisteringByAnatomicalLocation", "label": "Blistering by anatomical location", "logical_definition": null, "original_id": "HP:0033800", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBlisteringOfTheSkin" } ] }
0
{ "document": "Blistering by anatomical location Blistering (presence of multiple fluid filled blisters) categorized according to the body site where they occur. [{'predicate': 'subClassOf', 'target': 'AbnormalBlisteringOfTheSkin'}]" }
{ "aliases": null, "definition": "Blistering (presence of multiple fluid filled blisters) categorized according to the layer of the skin in which the blister originates. The skin is divided into three layers. The epidermis (outermost layer, which mainly consists of keratinocytes), the dermis, and a subcutaneous layer. The epidermis is divided into five layers: the basal lamina (innermost layer), the basal cell layer, the stratum spinosum, the stratum granulosum, and the stratum corneum (outermost layer). Cleavage in epidermolysis bullosa (EB) simplex occurs within the basal keratinocytes; in junctional EB, within the lamina lucida; and in dystrophic EB occurs in the sublamina densa, in the upper portion of the dermis (papillary dermis). In Kindler's EB, cleavage can occur in the basal keratinocytes, in the lamina lucida, or below the lamina densa.", "id": "BlisteringByHistologicalLocation", "label": "Blistering by histological location", "logical_definition": null, "original_id": "HP:0033801", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBlisteringOfTheSkin" } ] }
0
{ "document": "Blistering by histological location Blistering (presence of multiple fluid filled blisters) categorized according to the layer of the skin in which the blister originates. The skin is divided into three layers. The epidermis (outermost layer, which mainly consists of keratinocytes), the dermis, and a subcutaneous layer. The epidermis is divided into five layers: the basal lamina (innermost layer), the basal cell layer, the stratum spinosum, the stratum granulosum, and the stratum corneum (outermost layer). Cleavage in epidermolysis bullosa (EB) simplex occurs within the basal keratinocytes; in junctional EB, within the lamina lucida; and in dystrophic EB occurs in the sublamina densa, in the upper portion of the dermis (papillary dermis). In Kindler's EB, cleavage can occur in the basal keratinocytes, in the lamina lucida, or below the lamina densa. [{'predicate': 'subClassOf', 'target': 'AbnormalBlisteringOfTheSkin'}]" }
{ "aliases": null, "definition": "Congenital synostosis between two or more adjacent vertebrae (partial or complete fusion of adjacent vertabral bodies).", "id": "BlockVertebrae", "label": "Block vertebrae", "logical_definition": null, "original_id": "HP:0003305", "relationships": [ { "predicate": "subClassOf", "target": "VertebralFusion" } ] }
0
{ "document": "Block vertebrae Congenital synostosis between two or more adjacent vertebrae (partial or complete fusion of adjacent vertabral bodies). [{'predicate': 'subClassOf', 'target': 'VertebralFusion'}]" }
{ "aliases": null, "definition": null, "id": "BlockedEustachianTube", "label": "Blocked Eustachian tube", "logical_definition": null, "original_id": "HP:0040269", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalEustachianTubeMorphology" } ] }
0
{ "document": "Blocked Eustachian tube None [{'predicate': 'subClassOf', 'target': 'AbnormalEustachianTubeMorphology'}]" }
{ "aliases": null, "definition": "A fluid that is composed of blood plasma and erythrocytes.", "id": "Blood", "label": "blood", "logical_definition": null, "original_id": "UBERON:0000178", "relationships": [ { "predicate": "PartOf", "target": "HematopoieticSystem" }, { "predicate": "HasPart", "target": "Erythrocyte" }, { "predicate": "HasPart", "target": "BloodPlasma" }, { "predicate": "LocatedIn", "target": "Vasculature" }, { "predicate": "ImmediateTransformationOf", "target": "PresumptiveBlood" }, { "predicate": "subClassOf", "target": "HaemolymphaticFluid" } ] }
0
{ "document": "blood A fluid that is composed of blood plasma and erythrocytes. [{'predicate': 'PartOf', 'target': 'HematopoieticSystem'}, {'predicate': 'HasPart', 'target': 'Erythrocyte'}, {'predicate': 'HasPart', 'target': 'BloodPlasma'}, {'predicate': 'LocatedIn', 'target': 'Vasculature'}, {'predicate': 'ImmediateTransformationOf', 'target': 'PresumptiveBlood'}, {'predicate': 'subClassOf', 'target': 'HaemolymphaticFluid'}]" }
{ "aliases": null, "definition": "A cell found predominately in the blood.", "id": "BloodCell", "label": "blood cell", "logical_definition": null, "original_id": "CL:0000081", "relationships": [ { "predicate": "subClassOf", "target": "HematopoieticCell" } ] }
0
{ "document": "blood cell A cell found predominately in the blood. [{'predicate': 'subClassOf', 'target': 'HematopoieticCell'}]" }
{ "aliases": null, "definition": "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.", "id": "BloodCirculation", "label": "blood circulation", "logical_definition": null, "original_id": "GO:0008015", "relationships": [ { "predicate": "subClassOf", "target": "CirculatorySystemProcess" } ] }
0
{ "document": "blood circulation The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. [{'predicate': 'subClassOf', 'target': 'CirculatorySystemProcess'}]" }
{ "aliases": null, "definition": "A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network.", "id": "BloodClot", "label": "blood clot", "logical_definition": null, "original_id": "UBERON:0010210", "relationships": [ { "predicate": "HasPart", "target": "Erythrocyte" }, { "predicate": "HasPart", "target": "Platelet" }, { "predicate": "HasPart", "target": "Leukocyte" }, { "predicate": "HasPart", "target": "FibrinogenComplex" }, { "predicate": "DevelopsFrom", "target": "Blood" } ] }
0
{ "document": "blood clot A semisolid gelatinous mass of coagulated blood that consists of red blood cells, white blood cells, and platelets entrapped in a fibrin network. [{'predicate': 'HasPart', 'target': 'Erythrocyte'}, {'predicate': 'HasPart', 'target': 'Platelet'}, {'predicate': 'HasPart', 'target': 'Leukocyte'}, {'predicate': 'HasPart', 'target': 'FibrinogenComplex'}, {'predicate': 'DevelopsFrom', 'target': 'Blood'}]" }
{ "aliases": null, "definition": "The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.", "id": "BloodCoagulation", "label": "blood coagulation", "logical_definition": null, "original_id": "GO:0007596", "relationships": [ { "predicate": "PartOf", "target": "WoundHealing" }, { "predicate": "subClassOf", "target": "Hemostasis" }, { "predicate": "subClassOf", "target": "Coagulation" } ] }
0
{ "document": "blood coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. [{'predicate': 'PartOf', 'target': 'WoundHealing'}, {'predicate': 'subClassOf', 'target': 'Hemostasis'}, {'predicate': 'subClassOf', 'target': 'Coagulation'}]" }
{ "aliases": null, "definition": "A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.", "id": "BloodCoagulation_commonPathway", "label": "blood coagulation, common pathway", "logical_definition": null, "original_id": "GO:0072377", "relationships": [ { "predicate": "PartOf", "target": "BloodCoagulation_fibrinClotFormation" }, { "predicate": "subClassOf", "target": "ProteinActivationCascade" } ] }
0
{ "document": "blood coagulation, common pathway A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex. [{'predicate': 'PartOf', 'target': 'BloodCoagulation_fibrinClotFormation'}, {'predicate': 'subClassOf', 'target': 'ProteinActivationCascade'}]" }
{ "aliases": null, "definition": "A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.", "id": "BloodCoagulation_extrinsicPathway", "label": "blood coagulation, extrinsic pathway", "logical_definition": null, "original_id": "GO:0007598", "relationships": [ { "predicate": "PartOf", "target": "BloodCoagulation_fibrinClotFormation" }, { "predicate": "subClassOf", "target": "ProteinActivationCascade" } ] }
0
{ "document": "blood coagulation, extrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X. [{'predicate': 'PartOf', 'target': 'BloodCoagulation_fibrinClotFormation'}, {'predicate': 'subClassOf', 'target': 'ProteinActivationCascade'}]" }
{ "aliases": null, "definition": "A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.", "id": "BloodCoagulation_fibrinClotFormation", "label": "blood coagulation, fibrin clot formation", "logical_definition": null, "original_id": "GO:0072378", "relationships": [ { "predicate": "PartOf", "target": "BloodCoagulation" }, { "predicate": "subClassOf", "target": "ProteinActivationCascade" } ] }
0
{ "document": "blood coagulation, fibrin clot formation A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events. [{'predicate': 'PartOf', 'target': 'BloodCoagulation'}, {'predicate': 'subClassOf', 'target': 'ProteinActivationCascade'}]" }
{ "aliases": null, "definition": "A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.", "id": "BloodCoagulation_intrinsicPathway", "label": "blood coagulation, intrinsic pathway", "logical_definition": null, "original_id": "GO:0007597", "relationships": [ { "predicate": "PartOf", "target": "BloodCoagulation_fibrinClotFormation" }, { "predicate": "subClassOf", "target": "ProteinActivationCascade" } ] }
0
{ "document": "blood coagulation, intrinsic pathway A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X. [{'predicate': 'PartOf', 'target': 'BloodCoagulation_fibrinClotFormation'}, {'predicate': 'subClassOf', 'target': 'ProteinActivationCascade'}]" }
{ "aliases": null, "definition": "Any of the various types of human blood whose antigen characteristics determine compatibility in transfusion. While the ABO and Rhesus sytems are the most well known, there are in total about 300 different blood type antigens distributed across 34 different blood type systems.", "id": "BloodGroup", "label": "Blood group", "logical_definition": null, "original_id": "HP:0032223", "relationships": [ { "predicate": "subClassOf", "target": "All" } ] }
0
{ "document": "Blood group Any of the various types of human blood whose antigen characteristics determine compatibility in transfusion. While the ABO and Rhesus sytems are the most well known, there are in total about 300 different blood type antigens distributed across 34 different blood type systems. [{'predicate': 'subClassOf', 'target': 'All'}]" }
{ "aliases": null, "definition": "ABO phenotype A, corresponding to the genotype AO or AA.", "id": "BloodGroupA", "label": "Blood group A", "logical_definition": null, "original_id": "HP:0032370", "relationships": [ { "predicate": "subClassOf", "target": "ABOBloodGroup" } ] }
0
{ "document": "Blood group A ABO phenotype A, corresponding to the genotype AO or AA. [{'predicate': 'subClassOf', 'target': 'ABOBloodGroup'}]" }
{ "aliases": null, "definition": "ABO phenotype AB, corresponding to the genotype AB.", "id": "BloodGroupAB", "label": "Blood group AB", "logical_definition": null, "original_id": "HP:0032441", "relationships": [ { "predicate": "subClassOf", "target": "ABOBloodGroup" } ] }
0
{ "document": "Blood group AB ABO phenotype AB, corresponding to the genotype AB. [{'predicate': 'subClassOf', 'target': 'ABOBloodGroup'}]" }
{ "aliases": null, "definition": "An abnormality of an erythrocyte cell surface molecule.", "id": "BloodGroupAntigenAbnormality", "label": "Blood group antigen abnormality", "logical_definition": null, "original_id": "HP:0010970", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalErythrocyteMorphology" } ] }
0
{ "document": "Blood group antigen abnormality An abnormality of an erythrocyte cell surface molecule. [{'predicate': 'subClassOf', 'target': 'AbnormalErythrocyteMorphology'}]" }
{ "aliases": null, "definition": "ABO phenotype B, corresponding to the genotype BO or BB.", "id": "BloodGroupB", "label": "Blood group B", "logical_definition": null, "original_id": "HP:0032440", "relationships": [ { "predicate": "subClassOf", "target": "ABOBloodGroup" } ] }
0
{ "document": "Blood group B ABO phenotype B, corresponding to the genotype BO or BB. [{'predicate': 'subClassOf', 'target': 'ABOBloodGroup'}]" }
{ "aliases": null, "definition": "ABO phenotype O, corresponding to the genotype OO.", "id": "BloodGroupO", "label": "Blood group O", "logical_definition": null, "original_id": "HP:0032442", "relationships": [ { "predicate": "subClassOf", "target": "ABOBloodGroup" } ] }
0
{ "document": "Blood group O ABO phenotype O, corresponding to the genotype OO. [{'predicate': 'subClassOf', 'target': 'ABOBloodGroup'}]" }
{ "aliases": null, "definition": "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted].", "id": "BloodIsland", "label": "blood island", "logical_definition": null, "original_id": "UBERON:0003061", "relationships": [ { "predicate": "PartOf", "target": "Embryo" }, { "predicate": "DevelopsFrom", "target": "LateralPlateMesoderm" }, { "predicate": "HasPotentialToDevelopInto", "target": "HematopoieticSystem" }, { "predicate": "subClassOf", "target": "DevelopingAnatomicalStructure" } ] }
0
{ "document": "blood island Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. [{'predicate': 'PartOf', 'target': 'Embryo'}, {'predicate': 'DevelopsFrom', 'target': 'LateralPlateMesoderm'}, {'predicate': 'HasPotentialToDevelopInto', 'target': 'HematopoieticSystem'}, {'predicate': 'subClassOf', 'target': 'DevelopingAnatomicalStructure'}]" }
{ "aliases": null, "definition": "A lymphocyte located in blood.", "id": "BloodLymphocyte", "label": "blood lymphocyte", "logical_definition": null, "original_id": "CL:4030029", "relationships": null }
0
{ "document": "blood lymphocyte A lymphocyte located in blood. None" }
{ "aliases": null, "definition": "Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins.", "id": "BloodMicrovessel", "label": "blood microvessel", "logical_definition": null, "original_id": "UBERON:8410081", "relationships": [ { "predicate": "subClassOf", "target": "BloodVessel" }, { "predicate": "subClassOf", "target": "MicrocirculatoryVessel" } ] }
0
{ "document": "blood microvessel Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins. [{'predicate': 'subClassOf', 'target': 'BloodVessel'}, {'predicate': 'subClassOf', 'target': 'MicrocirculatoryVessel'}]" }
{ "aliases": null, "definition": "Detection of a parasitic organism in the blood stream. Blood parasites include malaria plasmodia, microfilaria species, trypanosomes (the causative agents of African sleeping sickness and South American Changas disease) and the causative agents of schistosomiasis of the bladder and the intestine.", "id": "BloodParasite", "label": "Blood parasite", "logical_definition": null, "original_id": "HP:0034523", "relationships": [ { "predicate": "subClassOf", "target": "BloodstreamInfectiousAgent" } ] }
0
{ "document": "Blood parasite Detection of a parasitic organism in the blood stream. Blood parasites include malaria plasmodia, microfilaria species, trypanosomes (the causative agents of African sleeping sickness and South American Changas disease) and the causative agents of schistosomiasis of the bladder and the intestine. [{'predicate': 'subClassOf', 'target': 'BloodstreamInfectiousAgent'}]" }
{ "aliases": null, "definition": "The liquid component of blood, in which erythrocytes are suspended.", "id": "BloodPlasma", "label": "blood plasma", "logical_definition": null, "original_id": "UBERON:0001969", "relationships": null }
0
{ "document": "blood plasma The liquid component of blood, in which erythrocytes are suspended. None" }
{ "aliases": null, "definition": "An abnormal blood pressure discrepancy between the upper and lower extremities with the blood pressure measured in the arms being much higher than the blood pressure measure in the legs. In healthy individuals, ankle systolic blood pressures are only slightly higher than the systolic blood pressure measured in the arm.", "id": "BloodPressureSubstantiallyHigherInArmsThanLegs", "label": "Blood pressure substantially higher in arms than legs", "logical_definition": null, "original_id": "HP:0020142", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSystemicBloodPressure" } ] }
0
{ "document": "Blood pressure substantially higher in arms than legs An abnormal blood pressure discrepancy between the upper and lower extremities with the blood pressure measured in the arms being much higher than the blood pressure measure in the legs. In healthy individuals, ankle systolic blood pressures are only slightly higher than the systolic blood pressure measured in the arm. [{'predicate': 'subClassOf', 'target': 'AbnormalSystemicBloodPressure'}]" }
{ "aliases": null, "definition": "An abnormal blood pressure discrepancy between the upper and lower extremities with the blood pressure measured in the legs being much higher than the blood pressure measure in the arms. In healthy individuals, ankle systolic blood pressures are only slightly higher than the systolic blood pressure measured in the arm.", "id": "BloodPressureSubstantiallyHigherInLegsThanArms", "label": "Blood pressure substantially higher in legs than arms", "logical_definition": null, "original_id": "HP:0020141", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalSystemicBloodPressure" } ] }
0
{ "document": "Blood pressure substantially higher in legs than arms An abnormal blood pressure discrepancy between the upper and lower extremities with the blood pressure measured in the legs being much higher than the blood pressure measure in the arms. In healthy individuals, ankle systolic blood pressures are only slightly higher than the systolic blood pressure measured in the arm. [{'predicate': 'subClassOf', 'target': 'AbnormalSystemicBloodPressure'}]" }
{ "aliases": null, "definition": "The portion of blood plasma that excludes clotting factors.", "id": "BloodSerum", "label": "blood serum", "logical_definition": null, "original_id": "UBERON:0001977", "relationships": [ { "predicate": "PartOf", "target": "BloodPlasma" }, { "predicate": "HasQuality", "target": "QualityOfALiquid" }, { "predicate": "subClassOf", "target": "OrganismSubstance" } ] }
0
{ "document": "blood serum The portion of blood plasma that excludes clotting factors. [{'predicate': 'PartOf', 'target': 'BloodPlasma'}, {'predicate': 'HasQuality', 'target': 'QualityOfALiquid'}, {'predicate': 'subClassOf', 'target': 'OrganismSubstance'}]" }
{ "aliases": null, "definition": "A vascular network consisting of blood vessels.", "id": "BloodVasculature", "label": "blood vasculature", "logical_definition": null, "original_id": "UBERON:0004537", "relationships": [ { "predicate": "PartOf", "target": "CardiovascularSystem" } ] }
0
{ "document": "blood vasculature A vascular network consisting of blood vessels. [{'predicate': 'PartOf', 'target': 'CardiovascularSystem'}]" }
{ "aliases": null, "definition": "A vessel through which blood circulates in the body.", "id": "BloodVessel", "label": "blood vessel", "logical_definition": null, "original_id": "UBERON:0001981", "relationships": [ { "predicate": "PartOf", "target": "BloodVasculature" }, { "predicate": "HasPart", "target": "BloodVesselEndothelialCell" }, { "predicate": "HasPart", "target": "EpithelialTubeOpenAtBothEnds" }, { "predicate": "HasQuality", "target": "Dendritic" }, { "predicate": "DevelopsFrom", "target": "SplanchnicLayerOfLateralPlateMesoderm" }, { "predicate": "DevelopsFrom", "target": "VascularCord" }, { "predicate": "CapableOfPartOf", "target": "BloodCirculation" }, { "predicate": "ChannelFor", "target": "Blood" }, { "predicate": "subClassOf", "target": "Vessel" } ] }
0
{ "document": "blood vessel A vessel through which blood circulates in the body. [{'predicate': 'PartOf', 'target': 'BloodVasculature'}, {'predicate': 'HasPart', 'target': 'BloodVesselEndothelialCell'}, {'predicate': 'HasPart', 'target': 'EpithelialTubeOpenAtBothEnds'}, {'predicate': 'HasQuality', 'target': 'Dendritic'}, {'predicate': 'DevelopsFrom', 'target': 'SplanchnicLayerOfLateralPlateMesoderm'}, {'predicate': 'DevelopsFrom', 'target': 'VascularCord'}, {'predicate': 'CapableOfPartOf', 'target': 'BloodCirculation'}, {'predicate': 'ChannelFor', 'target': 'Blood'}, {'predicate': 'subClassOf', 'target': 'Vessel'}]" }
{ "aliases": null, "definition": "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.", "id": "BloodVesselDevelopment", "label": "blood vessel development", "logical_definition": null, "original_id": "GO:0001568", "relationships": [ { "predicate": "PartOf", "target": "VasculatureDevelopment" }, { "predicate": "subClassOf", "target": "AnatomicalStructureDevelopment" } ] }
0
{ "document": "blood vessel development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. [{'predicate': 'PartOf', 'target': 'VasculatureDevelopment'}, {'predicate': 'subClassOf', 'target': 'AnatomicalStructureDevelopment'}]" }
{ "aliases": null, "definition": "Elastic tissue layer that lines a blood vessel layer.", "id": "BloodVesselElasticTissue", "label": "blood vessel elastic tissue", "logical_definition": null, "original_id": "UBERON:0003614", "relationships": null }
0
{ "document": "blood vessel elastic tissue Elastic tissue layer that lines a blood vessel layer. None" }
{ "aliases": null, "definition": "An endothelial cell that lines the vasculature.", "id": "BloodVesselEndothelialCell", "label": "blood vessel endothelial cell", "logical_definition": null, "original_id": "CL:0000071", "relationships": [ { "predicate": "DevelopsFrom", "target": "EmbryonicBloodVesselEndothelialProgenitorCell" }, { "predicate": "subClassOf", "target": "SquamousEpithelialCell" }, { "predicate": "subClassOf", "target": "EndothelialCellOfVascularTree" }, { "predicate": "subClassOf", "target": "SomaticCell" } ] }
0
{ "document": "blood vessel endothelial cell An endothelial cell that lines the vasculature. [{'predicate': 'DevelopsFrom', 'target': 'EmbryonicBloodVesselEndothelialProgenitorCell'}, {'predicate': 'subClassOf', 'target': 'SquamousEpithelialCell'}, {'predicate': 'subClassOf', 'target': 'EndothelialCellOfVascularTree'}, {'predicate': 'subClassOf', 'target': 'SomaticCell'}]" }
{ "aliases": null, "definition": "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart.", "id": "BloodVesselEndothelium", "label": "blood vessel endothelium", "logical_definition": null, "original_id": "UBERON:0004638", "relationships": null }
0
{ "document": "blood vessel endothelium An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. None" }
{ "aliases": null, "definition": "Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia.", "id": "BloodVesselLayer", "label": "blood vessel layer", "logical_definition": null, "original_id": "UBERON:0004797", "relationships": [ { "predicate": "PartOf", "target": "WallOfBloodVessel" } ] }
0
{ "document": "blood vessel layer Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. [{'predicate': 'PartOf', 'target': 'WallOfBloodVessel'}]" }
{ "aliases": null, "definition": "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.", "id": "BloodVesselMorphogenesis", "label": "blood vessel morphogenesis", "logical_definition": null, "original_id": "GO:0048514", "relationships": [ { "predicate": "PartOf", "target": "BloodVesselDevelopment" }, { "predicate": "subClassOf", "target": "TubeMorphogenesis" } ] }
0
{ "document": "blood vessel morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. [{'predicate': 'PartOf', 'target': 'BloodVesselDevelopment'}, {'predicate': 'subClassOf', 'target': 'TubeMorphogenesis'}]" }
{ "aliases": null, "definition": "A blood vessel that is part of a tympanic cavity [Automatically generated definition].", "id": "BloodVesselOfTympanicCavity", "label": "blood vessel of tympanic cavity", "logical_definition": null, "original_id": "UBERON:0004115", "relationships": [ { "predicate": "PartOf", "target": "MiddleEar" }, { "predicate": "subClassOf", "target": "BloodVessel" } ] }
0
{ "document": "blood vessel of tympanic cavity A blood vessel that is part of a tympanic cavity [Automatically generated definition]. [{'predicate': 'PartOf', 'target': 'MiddleEar'}, {'predicate': 'subClassOf', 'target': 'BloodVessel'}]" }
{ "aliases": null, "definition": "Smooth muscle found within, and composing the majority of the wall of blood vessels.", "id": "BloodVesselSmoothMuscle", "label": "blood vessel smooth muscle", "logical_definition": null, "original_id": "UBERON:0004237", "relationships": null }
0
{ "document": "blood vessel smooth muscle Smooth muscle found within, and composing the majority of the wall of blood vessels. None" }
{ "aliases": null, "definition": "A smooth muscle cell that is part of any blood vessel.", "id": "BloodVesselSmoothMuscleCell", "label": "blood vessel smooth muscle cell", "logical_definition": null, "original_id": "CL:0019018", "relationships": null }
0
{ "document": "blood vessel smooth muscle cell A smooth muscle cell that is part of any blood vessel. None" }
{ "aliases": null, "definition": "The presence of a xenobiotic in blood.", "id": "BloodXenobiotic", "label": "Blood xenobiotic", "logical_definition": null, "original_id": "HP:0410172", "relationships": [ { "predicate": "subClassOf", "target": "PresenceOfXenobiotic" } ] }
0
{ "document": "Blood xenobiotic The presence of a xenobiotic in blood. [{'predicate': 'subClassOf', 'target': 'PresenceOfXenobiotic'}]" }
{ "aliases": null, "definition": "The presence of an infectious agent in the blood circulation.", "id": "BloodstreamInfectiousAgent", "label": "Bloodstream infectious agent", "logical_definition": null, "original_id": "HP:0031863", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfMetabolismHomeostasis" } ] }
0
{ "document": "Bloodstream infectious agent The presence of an infectious agent in the blood circulation. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfMetabolismHomeostasis'}]" }
{ "aliases": null, "definition": "Presence of filaria in the blood stream. Filariasis is a common cause of elephantiasis in Coastal Districts of India. The initial manifestations are repeated episodes of fever with chills and rigor, lymphadenopathy which gradually progress to elephantiasis. In India filarial infestation is commonly caused by W. bancrofti and Brugia malayi, the former responsible for almost 98 percent of all cases.", "id": "BloodstreamMicrofilaria", "label": "Bloodstream microfilaria", "logical_definition": null, "original_id": "HP:0034639", "relationships": [ { "predicate": "subClassOf", "target": "BloodParasite" } ] }
0
{ "document": "Bloodstream microfilaria Presence of filaria in the blood stream. Filariasis is a common cause of elephantiasis in Coastal Districts of India. The initial manifestations are repeated episodes of fever with chills and rigor, lymphadenopathy which gradually progress to elephantiasis. In India filarial infestation is commonly caused by W. bancrofti and Brugia malayi, the former responsible for almost 98 percent of all cases. [{'predicate': 'subClassOf', 'target': 'BloodParasite'}]" }
{ "aliases": null, "definition": "Presence of Trypanosoma cruzi in the blood stream. Trypanosoma cruzii is the etiological agent of Chagas disease.", "id": "BloodstreamTrypanosomaCruzi", "label": "Bloodstream Trypanosoma cruzi", "logical_definition": null, "original_id": "HP:0034581", "relationships": [ { "predicate": "subClassOf", "target": "BloodParasite" } ] }
0
{ "document": "Bloodstream Trypanosoma cruzi Presence of Trypanosoma cruzi in the blood stream. Trypanosoma cruzii is the etiological agent of Chagas disease. [{'predicate': 'subClassOf', 'target': 'BloodParasite'}]" }
{ "aliases": null, "definition": "Presence of trypomastigote parasites in the blood stream. This finding can be demonstrated by the identification of trypomastigote parasites on peripheral blood smear.", "id": "BloodstreamTrypomastigotes", "label": "Bloodstream trypomastigotes", "logical_definition": null, "original_id": "HP:0034524", "relationships": [ { "predicate": "subClassOf", "target": "BloodParasite" } ] }
0
{ "document": "Bloodstream trypomastigotes Presence of trypomastigote parasites in the blood stream. This finding can be demonstrated by the identification of trypomastigote parasites on peripheral blood smear. [{'predicate': 'subClassOf', 'target': 'BloodParasite'}]" }
{ "aliases": null, "definition": "Return of lavage fluid characteristically has a bloody apperance in pulmonary alveolar hemorrhage. This is due to admixture of blood, which typically increases with each consecutive lavage portion. Microscopically erythrocytes can be seen. After 24 to 48 h macrophages contain phagocytosed erythrocytes, indicating previous bleeding.", "id": "BloodyBronchoalveolarLavageFluid", "label": "Bloody bronchoalveolar lavage fluid", "logical_definition": null, "original_id": "HP:0033174", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalBronchoalveolarLavageFluidMorphology" } ] }
0
{ "document": "Bloody bronchoalveolar lavage fluid Return of lavage fluid characteristically has a bloody apperance in pulmonary alveolar hemorrhage. This is due to admixture of blood, which typically increases with each consecutive lavage portion. Microscopically erythrocytes can be seen. After 24 to 48 h macrophages contain phagocytosed erythrocytes, indicating previous bleeding. [{'predicate': 'subClassOf', 'target': 'AbnormalBronchoalveolarLavageFluidMorphology'}]" }
{ "aliases": null, "definition": "Passage of many stools containing blood.", "id": "BloodyDiarrhea", "label": "Bloody diarrhea", "logical_definition": null, "original_id": "HP:0025085", "relationships": [ { "predicate": "subClassOf", "target": "Diarrhea" } ] }
0
{ "document": "Bloody diarrhea Passage of many stools containing blood. [{'predicate': 'subClassOf', 'target': 'Diarrhea'}]" }
{ "aliases": null, "definition": "Passage of many stools containing blood and mucus.", "id": "BloodyMucoidDiarrhea", "label": "Bloody mucoid diarrhea", "logical_definition": null, "original_id": "HP:0025086", "relationships": [ { "predicate": "subClassOf", "target": "BloodyDiarrhea" } ] }
0
{ "document": "Bloody mucoid diarrhea Passage of many stools containing blood and mucus. [{'predicate': 'subClassOf', 'target': 'BloodyDiarrhea'}]" }
{ "aliases": null, "definition": null, "id": "BlotchingPigmentationOfTheSkin", "label": "Blotching pigmentation of the skin", "logical_definition": null, "original_id": "HP:0007610", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfSkinPigmentation" } ] }
0
{ "document": "Blotching pigmentation of the skin None [{'predicate': 'subClassOf', 'target': 'AbnormalityOfSkinPigmentation'}]" }
{ "aliases": null, "definition": "A color hue with low wavelength of that portion of the visible spectrum lying between green and indigo, evoked in the human observer by radiant energy with wavelengths of approximately 420 to 490 nanometers.", "id": "Blue", "label": "blue", "logical_definition": null, "original_id": "PATO:0000318", "relationships": [ { "predicate": "subClassOf", "target": "Color" } ] }
0
{ "document": "blue A color hue with low wavelength of that portion of the visible spectrum lying between green and indigo, evoked in the human observer by radiant energy with wavelengths of approximately 420 to 490 nanometers. [{'predicate': 'subClassOf', 'target': 'Color'}]" }
{ "aliases": null, "definition": "A form of monochromacy in which vision is derived from the remaining preserved blue (S) cones and rod photoreceptors.", "id": "BlueConeMonochromacy", "label": "Blue cone monochromacy", "logical_definition": null, "original_id": "HP:0007939", "relationships": [ { "predicate": "subClassOf", "target": "ConeMonochromacy" } ] }
0
{ "document": "Blue cone monochromacy A form of monochromacy in which vision is derived from the remaining preserved blue (S) cones and rod photoreceptors. [{'predicate': 'subClassOf', 'target': 'ConeMonochromacy'}]" }
{ "aliases": null, "definition": "A markedly blue coloration of the iris.", "id": "BlueIrides", "label": "Blue irides", "logical_definition": null, "original_id": "HP:0000635", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalIrisPigmentation" } ] }
0
{ "document": "Blue irides A markedly blue coloration of the iris. [{'predicate': 'subClassOf', 'target': 'AbnormalIrisPigmentation'}]" }
{ "aliases": null, "definition": null, "id": "BlueNevus", "label": "Blue nevus", "logical_definition": null, "original_id": "HP:0100814", "relationships": [ { "predicate": "subClassOf", "target": "Nevus" } ] }
0
{ "document": "Blue nevus None [{'predicate': 'subClassOf', 'target': 'Nevus'}]" }
{ "aliases": null, "definition": "An abnormal bluish coloration of the sclera.", "id": "BlueSclerae", "label": "Blue sclerae", "logical_definition": null, "original_id": "HP:0000592", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalScleraMorphology" } ] }
0
{ "document": "Blue sclerae An abnormal bluish coloration of the sclera. [{'predicate': 'subClassOf', 'target': 'AbnormalScleraMorphology'}]" }
{ "aliases": null, "definition": "An abnormal blue color of the urine.", "id": "BlueUrine", "label": "Blue urine", "logical_definition": null, "original_id": "HP:0040317", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalUrinaryColor" } ] }
0
{ "document": "Blue urine An abnormal blue color of the urine. [{'predicate': 'subClassOf', 'target': 'AbnormalUrinaryColor'}]" }
{ "aliases": null, "definition": "Lack of sharpness of vision resulting in the inability to see fine detail.", "id": "BlurredVision", "label": "Blurred vision", "logical_definition": null, "original_id": "HP:0000622", "relationships": [ { "predicate": "subClassOf", "target": "AbnormalityOfVision" } ] }
0
{ "document": "Blurred vision Lack of sharpness of vision resulting in the inability to see fine detail. [{'predicate': 'subClassOf', 'target': 'AbnormalityOfVision'}]" }
{ "aliases": null, "definition": "A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.", "id": "Bm1BCell", "label": "Bm1 B cell", "logical_definition": null, "original_id": "CL:0000961", "relationships": [ { "predicate": "DevelopsFrom", "target": "TransitionalStageBCell" }, { "predicate": "subClassOf", "target": "FollicularBCell" } ] }
0
{ "document": "Bm1 B cell A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. [{'predicate': 'DevelopsFrom', 'target': 'TransitionalStageBCell'}, {'predicate': 'subClassOf', 'target': 'FollicularBCell'}]" }
{ "aliases": null, "definition": "A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.", "id": "Bm2BCell", "label": "Bm2 B cell", "logical_definition": null, "original_id": "CL:0000962", "relationships": [ { "predicate": "DevelopsFrom", "target": "Bm1BCell" }, { "predicate": "subClassOf", "target": "FollicularBCell" } ] }
0
{ "document": "Bm2 B cell A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. [{'predicate': 'DevelopsFrom', 'target': 'Bm1BCell'}, {'predicate': 'subClassOf', 'target': 'FollicularBCell'}]" }
{ "aliases": null, "definition": "A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.", "id": "Bm2_BCell", "label": "Bm2' B cell", "logical_definition": null, "original_id": "CL:0000964", "relationships": [ { "predicate": "DevelopsFrom", "target": "Bm2BCell" }, { "predicate": "subClassOf", "target": "GerminalCenterBCell" } ] }
0
{ "document": "Bm2' B cell A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. [{'predicate': 'DevelopsFrom', 'target': 'Bm2BCell'}, {'predicate': 'subClassOf', 'target': 'GerminalCenterBCell'}]" }
{ "aliases": null, "definition": "A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.", "id": "Bm3BCell", "label": "Bm3 B cell", "logical_definition": null, "original_id": "CL:0000965", "relationships": [ { "predicate": "DevelopsFrom", "target": "Bm2_BCell" }, { "predicate": "subClassOf", "target": "GerminalCenterBCell" } ] }
0
{ "document": "Bm3 B cell A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. [{'predicate': 'DevelopsFrom', 'target': 'Bm2_BCell'}, {'predicate': 'subClassOf', 'target': 'GerminalCenterBCell'}]" }
{ "aliases": null, "definition": "A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.", "id": "Bm3DeltaBCell", "label": "Bm3-delta B cell", "logical_definition": null, "original_id": "CL:0000963", "relationships": [ { "predicate": "DevelopsFrom", "target": "Bm3BCell" }, { "predicate": "subClassOf", "target": "GerminalCenterBCell" } ] }
0
{ "document": "Bm3-delta B cell A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. [{'predicate': 'DevelopsFrom', 'target': 'Bm3BCell'}, {'predicate': 'subClassOf', 'target': 'GerminalCenterBCell'}]" }
{ "aliases": null, "definition": "A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.", "id": "Bm4BCell", "label": "Bm4 B cell", "logical_definition": null, "original_id": "CL:0000966", "relationships": [ { "predicate": "DevelopsFrom", "target": "Bm3DeltaBCell" }, { "predicate": "subClassOf", "target": "GerminalCenterBCell" } ] }
0
{ "document": "Bm4 B cell A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. [{'predicate': 'DevelopsFrom', 'target': 'Bm3DeltaBCell'}, {'predicate': 'subClassOf', 'target': 'GerminalCenterBCell'}]" }
{ "aliases": null, "definition": "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not.", "id": "BodilyFluid", "label": "bodily fluid", "logical_definition": null, "original_id": "UBERON:0006314", "relationships": null }
0
{ "document": "bodily fluid Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. None" }
{ "aliases": null, "definition": "Any substance in the body or expelled from the body that is in a gaseous state.", "id": "BodilyGas", "label": "bodily gas", "logical_definition": null, "original_id": "UBERON:0034873", "relationships": null }
0
{ "document": "bodily gas Any substance in the body or expelled from the body that is in a gaseous state. None" }
{ "aliases": null, "definition": "Body ache is a complaint that is often used to denote vague symptoms of mild fatigue, lethargy, or dull aches. We will define it here to mean a dull and poorly localizable pain that is described by the affected individual to affect multiple joints or body parts or even the entire body.", "id": "BodyAche", "label": "Body ache", "logical_definition": null, "original_id": "HP:0033047", "relationships": [ { "predicate": "subClassOf", "target": "ConstitutionalSymptom" } ] }
0
{ "document": "Body ache Body ache is a complaint that is often used to denote vague symptoms of mild fatigue, lethargy, or dull aches. We will define it here to mean a dull and poorly localizable pain that is described by the affected individual to affect multiple joints or body parts or even the entire body. [{'predicate': 'subClassOf', 'target': 'ConstitutionalSymptom'}]" }
{ "aliases": null, "definition": "Dermal, epidermal, glandular and pigment structures of the body integument.", "id": "BodyExternalIntegumentStructure", "label": "body external integument structure", "logical_definition": null, "original_id": "UBERON:3000977", "relationships": null }
0
{ "document": "body external integument structure Dermal, epidermal, glandular and pigment structures of the body integument. None" }
{ "aliases": null, "definition": "The controlled release of a fluid by a cell or tissue in an animal.", "id": "BodyFluidSecretion", "label": "body fluid secretion", "logical_definition": null, "original_id": "GO:0007589", "relationships": [ { "predicate": "subClassOf", "target": "Secretion" }, { "predicate": "subClassOf", "target": "RegulationOfBodyFluidLevels" } ] }
0
{ "document": "body fluid secretion The controlled release of a fluid by a cell or tissue in an animal. [{'predicate': 'subClassOf', 'target': 'Secretion'}, {'predicate': 'subClassOf', 'target': 'RegulationOfBodyFluidLevels'}]" }
{ "aliases": null, "definition": "A perceived unpleasant smell given off by the body.", "id": "BodyOdor", "label": "Body odor", "logical_definition": null, "original_id": "HP:0500001", "relationships": [ { "predicate": "subClassOf", "target": "ConstitutionalSymptom" } ] }
0
{ "document": "Body odor A perceived unpleasant smell given off by the body. [{'predicate': 'subClassOf', 'target': 'ConstitutionalSymptom'}]" }
{ "aliases": null, "definition": "The body of ilium enters into the formation of the acetabulum, of which it forms rather less than two-fifths. Its external surface is partly articular, partly non-articular; the articular segment forms part of the lunate surface of the acetabulum, the non-articular portion contributes to the acetabular fossa. The internal surface of the body is part of the wall of the lesser pelvis and gives origin to some fibers of the Obturator internus. Below, it is continuous with the pelvic surfaces of the ischium and pubis, only a faint line indicating the place of union.", "id": "BodyOfIlium", "label": "body of ilium", "logical_definition": null, "original_id": "UBERON:0010747", "relationships": [ { "predicate": "PartOf", "target": "Ilium" }, { "predicate": "subClassOf", "target": "ZoneOfBoneOrgan" } ] }
0
{ "document": "body of ilium The body of ilium enters into the formation of the acetabulum, of which it forms rather less than two-fifths. Its external surface is partly articular, partly non-articular; the articular segment forms part of the lunate surface of the acetabulum, the non-articular portion contributes to the acetabular fossa. The internal surface of the body is part of the wall of the lesser pelvis and gives origin to some fibers of the Obturator internus. Below, it is continuous with the pelvic surfaces of the ischium and pubis, only a faint line indicating the place of union. [{'predicate': 'PartOf', 'target': 'Ilium'}, {'predicate': 'subClassOf', 'target': 'ZoneOfBoneOrgan'}]" }
{ "aliases": null, "definition": null, "id": "BodyOfRib", "label": "body of rib", "logical_definition": null, "original_id": "UBERON:0002231", "relationships": [ { "predicate": "PartOf", "target": "ProximalSegmentOfRib" }, { "predicate": "subClassOf", "target": "ZoneOfBoneOrgan" } ] }
0
{ "document": "body of rib None [{'predicate': 'PartOf', 'target': 'ProximalSegmentOfRib'}, {'predicate': 'subClassOf', 'target': 'ZoneOfBoneOrgan'}]" }
{ "aliases": null, "definition": "The body of the sphenoid bone, more or less cubical in shape, is hollowed out in its interior to form two large cavities, the sphenoidal air sinuses, which are separated from each other by a septum.", "id": "BodyOfSphenoid", "label": "body of sphenoid", "logical_definition": null, "original_id": "UBERON:0009639", "relationships": [ { "predicate": "PartOf", "target": "SphenoidBone" }, { "predicate": "PartOf", "target": "Chondrocranium" }, { "predicate": "PartOf", "target": "Basicranium" }, { "predicate": "DevelopsFrom", "target": "PrechordalCartilage" }, { "predicate": "DevelopsFrom", "target": "HypophysealCartilage" }, { "predicate": "subClassOf", "target": "BoneElement" } ] }
0
{ "document": "body of sphenoid The body of the sphenoid bone, more or less cubical in shape, is hollowed out in its interior to form two large cavities, the sphenoidal air sinuses, which are separated from each other by a septum. [{'predicate': 'PartOf', 'target': 'SphenoidBone'}, {'predicate': 'PartOf', 'target': 'Chondrocranium'}, {'predicate': 'PartOf', 'target': 'Basicranium'}, {'predicate': 'DevelopsFrom', 'target': 'PrechordalCartilage'}, {'predicate': 'DevelopsFrom', 'target': 'HypophysealCartilage'}, {'predicate': 'subClassOf', 'target': 'BoneElement'}]" }
{ "aliases": null, "definition": "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO].", "id": "BodyOfStomach", "label": "body of stomach", "logical_definition": null, "original_id": "UBERON:0001161", "relationships": [ { "predicate": "subClassOf", "target": "ZoneOfStomach" } ] }
0
{ "document": "body of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. [{'predicate': 'subClassOf', 'target': 'ZoneOfStomach'}]" }
{ "aliases": null, "definition": "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]", "id": "BodyPartMovement", "label": "body part movement", "logical_definition": null, "original_id": "NBO:0000001", "relationships": [ { "predicate": "subClassOf", "target": "KinestheticBehavior" } ] }
0
{ "document": "body part movement A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC] [{'predicate': 'subClassOf', 'target': 'KinestheticBehavior'}]" }
{ "aliases": null, "definition": "Intentionally or habitually assumed arrangement of the body.", "id": "BodyPosture", "label": "body posture", "logical_definition": null, "original_id": "NBO:0000356", "relationships": [ { "predicate": "HasParticipant_obo:nbo#has_participant", "target": "BodyWall" }, { "predicate": "subClassOf", "target": "Posture" } ] }
0
{ "document": "body posture Intentionally or habitually assumed arrangement of the body. [{'predicate': 'HasParticipant_obo:nbo#has_participant', 'target': 'BodyWall'}, {'predicate': 'subClassOf', 'target': 'Posture'}]" }
{ "aliases": null, "definition": "The region of the organism associated with the visceral organs.", "id": "BodyProper", "label": "body proper", "logical_definition": null, "original_id": "UBERON:0013702", "relationships": [ { "predicate": "PartOf", "target": "MainBodyAxis" }, { "predicate": "subClassOf", "target": "OrganismSubdivision" } ] }
0
{ "document": "body proper The region of the organism associated with the visceral organs. [{'predicate': 'PartOf', 'target': 'MainBodyAxis'}, {'predicate': 'subClassOf', 'target': 'OrganismSubdivision'}]" }
{ "aliases": null, "definition": "The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity.", "id": "BodyWall", "label": "body wall", "logical_definition": null, "original_id": "UBERON:0000309", "relationships": [ { "predicate": "subClassOf", "target": "OrganismSubdivision" } ] }
0
{ "document": "body wall The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity. [{'predicate': 'subClassOf', 'target': 'OrganismSubdivision'}]" }