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encing due to their vocal condition (Figure 8, Quotation 2)
Fifteen of the respondents cited using cannabinoids for
unrelated reasons such as for recreation, for anxiety or
depression, or for other unrelated medical conditions but
subsequently noticed improvements in their vocal dystonia
as well (Figure 8, Quotation 3)
Participants described the
effects of cannabinoids as more immediate than Botox in-
jections though shorter lasting than the effects of Botox
(Figure 8, Quotation 4)
Multiple participants described
cannabinoid products as an adjunct treatment that elon-
gated the effects of BTX injections (Figure 8, Quotation 5) or alleviated symptoms between Botox injections (Figure 8,
Quotation 6]
Respondents also reported the limitations of
using cannabinoid products for their vocal condition spe-
cifically noting the unwanted altered mental status when
using THC-derived products (Figure 8, Quotation 7), po-
tential cognitive slowing they experienced with long-term
use of THC (Figure 8, Quotation 8), and the inconsistent
effects of cannabinoid products due to the variable pre-
parations of products among innumerable providers in the
marketplace (Figure 8, Quotation 9)
Participants who ranked cannabinoid products as “in-
effective” frequently stated that cannabinoids had no effect
on their vocal condition (Figure 8, Quotation 10), that
Botox was the only consistent treatment that addressed
their vocal condition (Figure 8, Quotation 11), or that there
was no treatment that alleviated the symptoms of their
dystonia (Figure 8, Quotation 12)
DISCUSSION
Cannabinoids are compounds found in the cannabis plant
that interact with the body’s endocannabinoid system, which
plays a role in regulating a wide range of physiological
processes, including pain, inflammation, and mood (Huestis
2007).15 They have also been found to have antispasmodic
effects (Huestis 2007).15 A systematic review and meta-
analysis of 17 studies conducted by Brighina et al
(2020)
found that while cannabinoids show promise as a treatment
for dystonia, there is still insufficient evidence to support
their use as a regularly utilized medical treatment option.16
With this in mind, the utility of cannabinoid products as a
FIGURE 7
Bar chart displaying commonly cited improvements in voice quality after taking cannabinoids
Journal of Voice, Vol
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potential treatment for vocal dystonia has gained attention
in recent years, with some patients have reported anecdotal
benefits from using these products
Vocal dystonia is a neurological condition that affects
the muscles involved in voice production, resulting in in-
voluntary spasms, or contractions that interfere with
speech
In this study, we collected data from a total of 158
participants with vocal dystonia, vocal tremor, or muscle
tension dysphonia seeking to evaluate the prevalence and
patterns of use
Over one-half of the participants had tried
using cannabinoid products to treat their laryngeal dys-
tonia
Furthermore, roughly half (53.8%) of the re-
spondents in this group were currently using cannabinoids
as part of their treatment
Notably, most of those who
reported using cannabinoids did so without the guidance of
a medical professional, and only 9.4% of respondents had
learned about this option from their care team
With the majority of participants ranked cannabinoid
products as “ineffective” or “somewhat effective”, canna -
binoids appear ill-suited to serve as a stand-alone treat -
ment
This is supported by the fact that 55.6% of
respondents were using cannabinoids alongside another
treatment rather than cannabinoids by themselves
A large
proportion of participants who had previously tried using
cannabinoid products to treat their vocal dystonia had
discontinued their use often citing the ineffectiveness of the
products as their reason for discontinuation
Furthermore, in comparison to other treatments they had tried, half of
the participants polled perceived cannabinoids to represent
a less effective treatment
This study found that the majority of participants who
used cannabinoid products did so as a supplementary
treatment alongside conventional treatments provided by
healthcare professionals, such as laryngeal BTX and voice
therapy
When applied in conjunction with BTX, partici -
pants frequently perceived the combination of BTX and
cannabinoids as more effective than BTX alone
It is im-