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3A779342577.jsonld | ['Kultivierung von Produktionszelllinien und Entwicklung effizienter Analytik- und Aufreinigungsverfahren für die Zielproteine'] | ['Hybridom-Zellen, CHO-Zellen, Antikörper, Online-Prozessanalytik, 2D-Fluoreszenzspektroskopie, HPMDC, Antikörperaufreinigung, Membranadsorber. - Hybridoma cells, CHO cells, antibody, online process monitoring, 2D fluorescence spectroscopy, antibody purification, membrane adsorber'] | ['gnd:1051821436', 'gnd:4002290-0', 'gnd:4017701-4', 'gnd:4067547-6', 'gnd:4072641-1', 'gnd:4136607-4', 'gnd:4781219-9', 'gnd:4835248-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779342577'] | ['Anton, Fabienne', 'Antikörper', 'Fluoreszenzspektroskopie', 'Zellkultur', 'HPLC', 'Prozessanalyse', 'Aufreinigung', 'CHO-Zelle'] | Document
### Title: ['Kultivierung von Produktionszelllinien und Entwicklung effizienter Analytik- und Aufreinigungsverfahren für die Zielproteine']
### Abstract:
['Hybridom-Zellen, CHO-Zellen, Antikörper, Online-Prozessanalytik, 2D-Fluoreszenzspektroskopie, HPMDC, Antikörperaufreinigung, Membranadsorber. - Hybridoma cells, CHO cells, antibody, online process monitoring, 2D fluorescence spectroscopy, antibody purification, membrane adsorber']
### GND ID:
['gnd:1051821436', 'gnd:4002290-0', 'gnd:4017701-4', 'gnd:4067547-6', 'gnd:4072641-1', 'gnd:4136607-4', 'gnd:4781219-9', 'gnd:4835248-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779342577']
### GND class:
['Anton, Fabienne', 'Antikörper', 'Fluoreszenzspektroskopie', 'Zellkultur', 'HPLC', 'Prozessanalyse', 'Aufreinigung', 'CHO-Zelle']
<|eot_id|> |
3A779371933.jsonld | ['Spectral triples on Carnot manifolds'] | ['Spectral triple, Carnot-Carathéodory metric, hypoellipticity. - Spektrales Tripel, Carnot-Carathéodory Metrik, Hypoelliptizität'] | ['gnd:1051820278', 'gnd:4012248-7', 'gnd:4138891-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779371933'] | ['Hasselmann, Stefan', 'Differentialgeometrie', 'Hypoelliptischer Operator'] | Document
### Title: ['Spectral triples on Carnot manifolds']
### Abstract:
['Spectral triple, Carnot-Carathéodory metric, hypoellipticity. - Spektrales Tripel, Carnot-Carathéodory Metrik, Hypoelliptizität']
### GND ID:
['gnd:1051820278', 'gnd:4012248-7', 'gnd:4138891-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779371933']
### GND class:
['Hasselmann, Stefan', 'Differentialgeometrie', 'Hypoelliptischer Operator']
<|eot_id|> |
3A779699378.jsonld | ['Dynamical tuning of a signal recycled gravitational wave detector : dynamical effects and sensitivity gain of dynamical tuning during detection of a chirp signal from compact binary coalescences'] | ['Gravitational waves, chirp signals, signal recycling, GEO 600, dynamical tuning. - Gravitationswellen, Chirpsignale, Signal-Recycling, dynamisches Tuning'] | ['gnd:1051959632', 'gnd:4140518-3', 'gnd:4150454-9', 'gnd:4185135-3', 'gnd:4245097-4', 'gnd:4352109-5', 'gnd:4566082-7', 'gnd:4576163-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779699378'] | ['Simakov, Dmitry', 'Michelson-Interferometer', 'Doppelstern', 'Thermisches Rauschen', 'Fabry-Pérot-Resonator', 'Schrotrauschen', 'Chirp', 'Gravitationswellendetektor'] | Document
### Title: ['Dynamical tuning of a signal recycled gravitational wave detector : dynamical effects and sensitivity gain of dynamical tuning during detection of a chirp signal from compact binary coalescences']
### Abstract:
['Gravitational waves, chirp signals, signal recycling, GEO 600, dynamical tuning. - Gravitationswellen, Chirpsignale, Signal-Recycling, dynamisches Tuning']
### GND ID:
['gnd:1051959632', 'gnd:4140518-3', 'gnd:4150454-9', 'gnd:4185135-3', 'gnd:4245097-4', 'gnd:4352109-5', 'gnd:4566082-7', 'gnd:4576163-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779699378']
### GND class:
['Simakov, Dmitry', 'Michelson-Interferometer', 'Doppelstern', 'Thermisches Rauschen', 'Fabry-Pérot-Resonator', 'Schrotrauschen', 'Chirp', 'Gravitationswellendetektor']
<|eot_id|> |
3A779744276.jsonld | ['Determinants of successful luxury brand management in turbulent times'] | ['Luxury brand management, counterfeit consumption, marketing trends. - Luxusmarkenmanagement, Fälschungskauf, Marketingtrends'] | ['gnd:1051838754', 'gnd:4168907-0', 'gnd:4544744-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779744276'] | ['Klarmann, Christiane', 'Marketingmanagement', 'Luxusgüterhandel'] | Document
### Title: ['Determinants of successful luxury brand management in turbulent times']
### Abstract:
['Luxury brand management, counterfeit consumption, marketing trends. - Luxusmarkenmanagement, Fälschungskauf, Marketingtrends']
### GND ID:
['gnd:1051838754', 'gnd:4168907-0', 'gnd:4544744-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A779744276']
### GND class:
['Klarmann, Christiane', 'Marketingmanagement', 'Luxusgüterhandel']
<|eot_id|> |
3A780078284.jsonld | ['Dynamics of hydrogen bonds in the melt-state of supramolecular polymers'] | [['supramolecular polymers; hydrogen bonding; click chemistry; self-healing; polyisobutylene; poly(n-butyl acrylate); LCCP; ATRP', 'Das Assoziations- und Aggregationsverhalten von verschiedenen Wasserstoffbrückenbindungssystemen wurde in der Polymerschmelze von amorphen Polymeren untersucht. Polyisobutylen (PIB) und Poly(n-butylacrylat) wurden mittels lebenden Polymerisationsmethoden dargestellt. Die Anbindung der funktionellen Gruppen erfolge über Azid/Alkin “Click”-Reaktionen. Als Wasserstoffbrückenbindungssysteme wurden Thymin/2,6-Diaminotriazin (THY/DAT) und Barbitursäure/Hamilton Rezeptor (BA/HW) verwendet. Das Verhalten in der Polymerschmelze wurde mittels Schmelzrheologie und SAXS untersucht. Es konnte gezeigt werden, dass die Assoziation in Lösung grundverschieden von der Aggregation in der Schmelze ist. Für Barbitursäure-funktionalisierte PIBs konnte mittels mechanischer Analyse selbstheilendes Verhalten gezeigt werden.', 'The association and aggregation behavior of different hydrogen bonding motifs was studied in solution and the melt state of amorphous polymers. Polyisobutylene (PIB) and Poly(n-butyl acrylate) (PnBA) were synthesized by living polymerization methods. The hydrogen bonding groups were attached by azid/alkyne „click“ reactions. As hydrogen bonding motifs the thymine/2,6-diaminotriazine (THY/DAT) and the barbituric acid/Hamilton wedge (BA/HW) system were applied. The behavior in the melt state was studied by rheology and SAXS. It was shown that the association in solution is completely different from the aggregation in the melt state. For barbituric acid functionalized PIBs self-healing behavior was observed and studied via mechanical analysis.', 'supramolekulare Polymere; Wasserstoffbrückenbindung; Klick Chemie; Selbstheilung; Polyisobuten; Poly(n-butylacrylat); LCCP; ATRP']] | ['gnd:4046699-1', 'gnd:4064787-0', 'gnd:4306141-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780078284'] | ['Polymere', 'Wasserstoffbrückenbindung', 'Supramolekulare Chemie'] | Document
### Title: ['Dynamics of hydrogen bonds in the melt-state of supramolecular polymers']
### Abstract:
[['supramolecular polymers; hydrogen bonding; click chemistry; self-healing; polyisobutylene; poly(n-butyl acrylate); LCCP; ATRP', 'Das Assoziations- und Aggregationsverhalten von verschiedenen Wasserstoffbrückenbindungssystemen wurde in der Polymerschmelze von amorphen Polymeren untersucht. Polyisobutylen (PIB) und Poly(n-butylacrylat) wurden mittels lebenden Polymerisationsmethoden dargestellt. Die Anbindung der funktionellen Gruppen erfolge über Azid/Alkin “Click”-Reaktionen. Als Wasserstoffbrückenbindungssysteme wurden Thymin/2,6-Diaminotriazin (THY/DAT) und Barbitursäure/Hamilton Rezeptor (BA/HW) verwendet. Das Verhalten in der Polymerschmelze wurde mittels Schmelzrheologie und SAXS untersucht. Es konnte gezeigt werden, dass die Assoziation in Lösung grundverschieden von der Aggregation in der Schmelze ist. Für Barbitursäure-funktionalisierte PIBs konnte mittels mechanischer Analyse selbstheilendes Verhalten gezeigt werden.', 'The association and aggregation behavior of different hydrogen bonding motifs was studied in solution and the melt state of amorphous polymers. Polyisobutylene (PIB) and Poly(n-butyl acrylate) (PnBA) were synthesized by living polymerization methods. The hydrogen bonding groups were attached by azid/alkyne „click“ reactions. As hydrogen bonding motifs the thymine/2,6-diaminotriazine (THY/DAT) and the barbituric acid/Hamilton wedge (BA/HW) system were applied. The behavior in the melt state was studied by rheology and SAXS. It was shown that the association in solution is completely different from the aggregation in the melt state. For barbituric acid functionalized PIBs self-healing behavior was observed and studied via mechanical analysis.', 'supramolekulare Polymere; Wasserstoffbrückenbindung; Klick Chemie; Selbstheilung; Polyisobuten; Poly(n-butylacrylat); LCCP; ATRP']]
### GND ID:
['gnd:4046699-1', 'gnd:4064787-0', 'gnd:4306141-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780078284']
### GND class:
['Polymere', 'Wasserstoffbrückenbindung', 'Supramolekulare Chemie']
<|eot_id|> |
3A78030747X.jsonld | ['Characterisation of a personal learning environment as a lifelong learning tool'] | ['"Over the last years, increasing attention has been paid to Personal Learning Environments (PLEs) as an effective framework for lifelong learners, and to the need for a smooth integration of formal and informal learning. A wider and wider range of open source and free learning applications on the web are offering lifelong learners powerful tools to construct and characterise their own PLEs. Technologically speaking, this change of perspective manifests in a learning web where information is distributed across sites. However, knowledge management becomes an issue, and personalisation requires the support of semantics applied to social components. This work focuses on the characterisation of adult lifelong learners\' PLEs by implicit and explicit tools of personalisation"--Back cover'] | ['gnd:4015428-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78030747X'] | ['Erwachsenenbildung'] | Document
### Title: ['Characterisation of a personal learning environment as a lifelong learning tool']
### Abstract:
['"Over the last years, increasing attention has been paid to Personal Learning Environments (PLEs) as an effective framework for lifelong learners, and to the need for a smooth integration of formal and informal learning. A wider and wider range of open source and free learning applications on the web are offering lifelong learners powerful tools to construct and characterise their own PLEs. Technologically speaking, this change of perspective manifests in a learning web where information is distributed across sites. However, knowledge management becomes an issue, and personalisation requires the support of semantics applied to social components. This work focuses on the characterisation of adult lifelong learners\' PLEs by implicit and explicit tools of personalisation"--Back cover']
### GND ID:
['gnd:4015428-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78030747X']
### GND class:
['Erwachsenenbildung']
<|eot_id|> |
3A780308212.jsonld | ['Essays on nonlinear and explosive time series : with applications to financial markets'] | ['Bias correction, explosive behavior, non-linearity, model selection, persistence, specification testing. - Bias Korrektur, explosives Verhalten, Nichtlinearität, Modellselektion, Persistenz, Spezifikationstests'] | ['gnd:1051940907', 'gnd:4067486-1', 'gnd:4077852-6', 'gnd:4170297-9', 'gnd:4251077-6', 'gnd:4372292-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780308212'] | ['Kaufmann, Hendrik', 'Zeitreihenanalyse', 'Statistischer Test', 'Modellierung', 'Nichtlineare Regression', 'Systematischer Fehler'] | Document
### Title: ['Essays on nonlinear and explosive time series : with applications to financial markets']
### Abstract:
['Bias correction, explosive behavior, non-linearity, model selection, persistence, specification testing. - Bias Korrektur, explosives Verhalten, Nichtlinearität, Modellselektion, Persistenz, Spezifikationstests']
### GND ID:
['gnd:1051940907', 'gnd:4067486-1', 'gnd:4077852-6', 'gnd:4170297-9', 'gnd:4251077-6', 'gnd:4372292-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780308212']
### GND class:
['Kaufmann, Hendrik', 'Zeitreihenanalyse', 'Statistischer Test', 'Modellierung', 'Nichtlineare Regression', 'Systematischer Fehler']
<|eot_id|> |
3A780316452.jsonld | ['Immune evasion proteins from Staphylococcus aureus and therapeutic evaluation of staphylococcal complement-controlling proteins'] | ['Complement as a central element of human host innate immunity provides defense against infectious microbes. However, the human pathogen Staphylococcus aureus expresses multiple complement inhibitors including the extracellular fibrinogen-binding protein (Efb). Its complement inhibitory mechanism at the molecular level, however, is still poorly understood. Complement also can be very harmful to the human host when inadequately regulated as demonstrated by the occurrence of complement-mediated diseases. A need for complement control is therefore necessary and in this context, staphylococcal complement inhibitors have a high anti-inflammatory potential. It was therefore the goal of this study to describe the complement inhibitory mechanism of Efb and to examine the protective potential of it in complement-mediated cell damage. Efb acquires the central complement proteins Factor H and C3 to form a tripartite complex. Within the complex, Efb induces a conformational change of C3 which makes it highly susceptible for cleavage by the human serine protease Factor I, making C3 incapable of participating in the complement activation.'] | ['gnd:1032386185', 'gnd:104692463X', 'gnd:36164-1', 'gnd:4120589-3', 'gnd:4182912-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780316452'] | ['Immunevasion', 'Böhm, Sascha', 'Friedrich-Schiller-Universität Jena', 'Komplement (Immunologie)', 'Staphylococcus aureus'] | Document
### Title: ['Immune evasion proteins from Staphylococcus aureus and therapeutic evaluation of staphylococcal complement-controlling proteins']
### Abstract:
['Complement as a central element of human host innate immunity provides defense against infectious microbes. However, the human pathogen Staphylococcus aureus expresses multiple complement inhibitors including the extracellular fibrinogen-binding protein (Efb). Its complement inhibitory mechanism at the molecular level, however, is still poorly understood. Complement also can be very harmful to the human host when inadequately regulated as demonstrated by the occurrence of complement-mediated diseases. A need for complement control is therefore necessary and in this context, staphylococcal complement inhibitors have a high anti-inflammatory potential. It was therefore the goal of this study to describe the complement inhibitory mechanism of Efb and to examine the protective potential of it in complement-mediated cell damage. Efb acquires the central complement proteins Factor H and C3 to form a tripartite complex. Within the complex, Efb induces a conformational change of C3 which makes it highly susceptible for cleavage by the human serine protease Factor I, making C3 incapable of participating in the complement activation.']
### GND ID:
['gnd:1032386185', 'gnd:104692463X', 'gnd:36164-1', 'gnd:4120589-3', 'gnd:4182912-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780316452']
### GND class:
['Immunevasion', 'Böhm, Sascha', 'Friedrich-Schiller-Universität Jena', 'Komplement (Immunologie)', 'Staphylococcus aureus']
<|eot_id|> |
3A780412567.jsonld | ['Trusted community : a novel multiagent organisation for open distributed systems'] | ['Open distributed systems, organic computing, multiagent systems, MAS organisations, trust and reputation, desktop grid systems. - Offene verteilte Systeme, Multiagentensysteme, Multiagentenorganisationen, Vertrauen und Reputation, Desktop Grid Systeme'] | ['gnd:1053835183', 'gnd:4238872-7', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780412567'] | ['Klejnowski, Lukas', 'Verteiltes System', 'Mehragentensystem'] | Document
### Title: ['Trusted community : a novel multiagent organisation for open distributed systems']
### Abstract:
['Open distributed systems, organic computing, multiagent systems, MAS organisations, trust and reputation, desktop grid systems. - Offene verteilte Systeme, Multiagentensysteme, Multiagentenorganisationen, Vertrauen und Reputation, Desktop Grid Systeme']
### GND ID:
['gnd:1053835183', 'gnd:4238872-7', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780412567']
### GND class:
['Klejnowski, Lukas', 'Verteiltes System', 'Mehragentensystem']
<|eot_id|> |
3A780586875.jsonld | ['Entwicklung von Simulationsmodellen für kristalline Silizium-Solarzellen : theoretische Studien zum Potential der PSG-Diffusion, von Galliumphosphid-Silizium-Heterostrukturen und der Charakterisierung von multikristallinem Silizium'] | ['Solarzellsimulationen, Phosphorsilikatglas, Galliumphosphid, Heterostruktur, multikristallines Silizium. - Solar cell simulations, phosphosilicate glass, gallium phosphide, heterostructure, multi-crystalline silicon'] | ['gnd:1051951135', 'gnd:4012277-3', 'gnd:4021142-3', 'gnd:4033209-3', 'gnd:4055072-2', 'gnd:4077445-4', 'gnd:4123378-5', 'gnd:4152082-8', 'gnd:4155879-0', 'gnd:4174454-8', 'gnd:4181740-0', 'gnd:4188261-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780586875'] | ['Wagner, Hannes', 'Diffusion', 'Glas', 'Kristall', 'Simulation', 'Silicium', 'Heterostruktur', 'Emitter', 'Galliumphosphid', 'Phosphorverbindungen', 'Solarzelle', 'Polykristall'] | Document
### Title: ['Entwicklung von Simulationsmodellen für kristalline Silizium-Solarzellen : theoretische Studien zum Potential der PSG-Diffusion, von Galliumphosphid-Silizium-Heterostrukturen und der Charakterisierung von multikristallinem Silizium']
### Abstract:
['Solarzellsimulationen, Phosphorsilikatglas, Galliumphosphid, Heterostruktur, multikristallines Silizium. - Solar cell simulations, phosphosilicate glass, gallium phosphide, heterostructure, multi-crystalline silicon']
### GND ID:
['gnd:1051951135', 'gnd:4012277-3', 'gnd:4021142-3', 'gnd:4033209-3', 'gnd:4055072-2', 'gnd:4077445-4', 'gnd:4123378-5', 'gnd:4152082-8', 'gnd:4155879-0', 'gnd:4174454-8', 'gnd:4181740-0', 'gnd:4188261-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780586875']
### GND class:
['Wagner, Hannes', 'Diffusion', 'Glas', 'Kristall', 'Simulation', 'Silicium', 'Heterostruktur', 'Emitter', 'Galliumphosphid', 'Phosphorverbindungen', 'Solarzelle', 'Polykristall']
<|eot_id|> |
3A780688767.jsonld | ['Partition coefficients in mixed surfactant systems'] | [['In this work the applicability of surfactants in novel separation processes is investigated. The surfactant/ water phase behavior and micelle/ water partition coefficients were determined, considering the influence of alcohols, the pH value and surfactant mixtures. Based on the experimental and predicted (COSMO-RS) results, the implementation of surfactant based systems is demonstrated.', 'In der vorliegenden Arbeit wird eine Methode entwickelt, die es ermöglicht die Eignung von Tensiden für neuartige Trennprozesse zu evaluieren. Hierzu werden Tensid/ Wasser Phasengleichgewichte und Mizelle/ Wasser Verteilungskoeffizienten ermittelt, unter der Berücksichtigung des Einflusses von Alkoholen, pH Wert und Tensidmischungen. Basierend auf experimentellen und prädiktiven (COSMO-RS) Ergebnissen wird die Implementierung von Tensidsystemen anhand von Beispielen demonstriert.']] | ['gnd:10199933-1', 'gnd:1053356129', 'gnd:1135633649', 'gnd:173623719', 'gnd:4013585-8', 'gnd:4078395-9', 'gnd:4128790-3', 'gnd:4130524-3', 'gnd:4188063-8', 'gnd:4511937-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780688767'] | ['Technische Universität Hamburg-Harburg, Institut für Thermische Verfahrenstechnik', 'Mehling, Tanja', 'Smirnova, Irina', 'Sadowski, Gabriele', 'Effizienz', 'Trennverfahren', 'Tensid', 'Micelle', 'Verteilungskoeffizient', 'Online-Ressource'] | Document
### Title: ['Partition coefficients in mixed surfactant systems']
### Abstract:
[['In this work the applicability of surfactants in novel separation processes is investigated. The surfactant/ water phase behavior and micelle/ water partition coefficients were determined, considering the influence of alcohols, the pH value and surfactant mixtures. Based on the experimental and predicted (COSMO-RS) results, the implementation of surfactant based systems is demonstrated.', 'In der vorliegenden Arbeit wird eine Methode entwickelt, die es ermöglicht die Eignung von Tensiden für neuartige Trennprozesse zu evaluieren. Hierzu werden Tensid/ Wasser Phasengleichgewichte und Mizelle/ Wasser Verteilungskoeffizienten ermittelt, unter der Berücksichtigung des Einflusses von Alkoholen, pH Wert und Tensidmischungen. Basierend auf experimentellen und prädiktiven (COSMO-RS) Ergebnissen wird die Implementierung von Tensidsystemen anhand von Beispielen demonstriert.']]
### GND ID:
['gnd:10199933-1', 'gnd:1053356129', 'gnd:1135633649', 'gnd:173623719', 'gnd:4013585-8', 'gnd:4078395-9', 'gnd:4128790-3', 'gnd:4130524-3', 'gnd:4188063-8', 'gnd:4511937-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780688767']
### GND class:
['Technische Universität Hamburg-Harburg, Institut für Thermische Verfahrenstechnik', 'Mehling, Tanja', 'Smirnova, Irina', 'Sadowski, Gabriele', 'Effizienz', 'Trennverfahren', 'Tensid', 'Micelle', 'Verteilungskoeffizient', 'Online-Ressource']
<|eot_id|> |
3A780759052.jsonld | ['Ein rauscharmes Materiewellen-Gyroskop hoher Genauigkeit'] | ['Atominterferometer, Sagnac-Effekt, Rotationsmessung, Stabilität, Genauigkeit. - Atom interferometer, Sagnac effect, rotation measurement, stability, accuracy'] | ['gnd:1051831296', 'gnd:4158614-1', 'gnd:4176912-0', 'gnd:4178921-0', 'gnd:4297488-4', 'gnd:4470214-0', 'gnd:4522144-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780759052'] | ['Berg, Peter', 'Gyroskop', 'Raman-Effekt', 'Sagnac-Effekt', 'Laserkühlung', 'Rubidium-87', 'Atominterferometrie'] | Document
### Title: ['Ein rauscharmes Materiewellen-Gyroskop hoher Genauigkeit']
### Abstract:
['Atominterferometer, Sagnac-Effekt, Rotationsmessung, Stabilität, Genauigkeit. - Atom interferometer, Sagnac effect, rotation measurement, stability, accuracy']
### GND ID:
['gnd:1051831296', 'gnd:4158614-1', 'gnd:4176912-0', 'gnd:4178921-0', 'gnd:4297488-4', 'gnd:4470214-0', 'gnd:4522144-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A780759052']
### GND class:
['Berg, Peter', 'Gyroskop', 'Raman-Effekt', 'Sagnac-Effekt', 'Laserkühlung', 'Rubidium-87', 'Atominterferometrie']
<|eot_id|> |
3A781067804.jsonld | ['Isolation, structure elucidation and characterization of bacterial siderophores'] | ['In this thesis a genome mining approach including bioinformatic predictions of natural product biosynthesis gene clusters was used to detect and isolate putative siderophores (small molecule iron transporters) from underexplored ß-proteobacteria. In the first part of this study, the novel iron chelating lipopeptides cupriachelin from Cupriavidus necator and taiwachelin from Cupriavidus taiwanensis were discovered and chemically analyzed. Both natural products showed iron-dependent photoreactivity when exposed to sunlight. In course of the photodissociation, Fe(III) is reduced to highly soluble Fe(II). A reaction which might be important for the ecological iron cycling in aqueous habitats. The second part of this study is focused on the biosynthesis of the antimycoplasma agent micacocidin from the plant pathogen Ralstonia solanacearum. Dissection of an unusual polyketide synthase module helped identifying the assembly process of the aromatic starter unit 6-pentylsalicylic acid. Moreover it could be shown that the iterative type I polyketide synthase is tolerant towards incorporation of unnatural starter units. A precursor-directed biosynthesis led to the isolation of numerous micacocidin derivatives with promising'] | ['gnd:1048022625', 'gnd:36164-1', 'gnd:4235006-2', 'gnd:4397407-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781067804'] | ['Kreutzer, Martin Florian', 'Friedrich-Schiller-Universität Jena', 'Siderophore', 'Proteobakterien'] | Document
### Title: ['Isolation, structure elucidation and characterization of bacterial siderophores']
### Abstract:
['In this thesis a genome mining approach including bioinformatic predictions of natural product biosynthesis gene clusters was used to detect and isolate putative siderophores (small molecule iron transporters) from underexplored ß-proteobacteria. In the first part of this study, the novel iron chelating lipopeptides cupriachelin from Cupriavidus necator and taiwachelin from Cupriavidus taiwanensis were discovered and chemically analyzed. Both natural products showed iron-dependent photoreactivity when exposed to sunlight. In course of the photodissociation, Fe(III) is reduced to highly soluble Fe(II). A reaction which might be important for the ecological iron cycling in aqueous habitats. The second part of this study is focused on the biosynthesis of the antimycoplasma agent micacocidin from the plant pathogen Ralstonia solanacearum. Dissection of an unusual polyketide synthase module helped identifying the assembly process of the aromatic starter unit 6-pentylsalicylic acid. Moreover it could be shown that the iterative type I polyketide synthase is tolerant towards incorporation of unnatural starter units. A precursor-directed biosynthesis led to the isolation of numerous micacocidin derivatives with promising']
### GND ID:
['gnd:1048022625', 'gnd:36164-1', 'gnd:4235006-2', 'gnd:4397407-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781067804']
### GND class:
['Kreutzer, Martin Florian', 'Friedrich-Schiller-Universität Jena', 'Siderophore', 'Proteobakterien']
<|eot_id|> |
3A781231825.jsonld | ['Schlammablagerungen in urbanen Vorflutern : Ursachen, Schwermetallbelastung und Remobilisierbarkeit untersucht an Vorflutern der Saaleaue bei Halle'] | [['sludge; combined stormwater-sewage drainage system; stormwater overflows; remobilisation; resuspension; flood; heavy metals; mercury; floodplain contamination; Chemische Werke Buna', 'Die Arbeit untersucht die Herkunft von starkmächtigen Faulschlammablagerungen in Nebenarmen der Saale die aufgrund hoher Quecksilbergehalte durch mehrere Gutachten als Folge von Abwassereinleitungen der chemischen Industrie oberhalb von Halle klassifiziert wurden. Ausgehend von der Fragestellung, ob es durch das ‚Jahrhunderthochwasser’ der Saale im April 1994 zur natürlichen Ausräumung der Schlämme gekommen ist, weist der Autor nach: a) daß dies nicht der Fall gewesen ist und auch nicht in Zukunft sein wird, b) daß die Schlämme nicht durch die Abwässer der stromaufwärtsliegenden chemischen Industrie entstanden sind, sondern durch niederschlagsbedingte Abwassereinleitungen aus dem überalterten Kanalisationsnetz. Dies wird u.a. mit Hilfe von detaillierten Kartierungen der Schlammmächtigkeit und ihrer Lagebeziehungen, standortspezifischen Modellen zur Massenbilianzierung der Schlämme unter Berücksichtigung der Eigenschaften der städtischen Einzugsgebiete, sowie geochemischem Fingerprinting mittels Schwermetallen und in-vitro Videobeobachtungen des Sedimentationsverhaltens abwasserbürtiger Schwebstoffe nachgewiesen.', 'The study investigates the origin of thick deposits of sludge accumulated in urban branches of the river Saale. Owing to high levels of mercury contained in the sludge previous studies identified upstream waste water discharges from the chemical industry as cause of the problem. Starting from the initial question whether the extreme flood of April 1994 naturally removed the sludge from the stream channel the author proves that a) this was not the case and will not happen in future; b) that the sludge was not caused by waste water from the upstream chemical industry but by rain-triggered combined stormwater-sewage discharges from an aged and overstretched municipal drainage system. This is based, among others, on detailed mapping of sludge thickness and associated analysis of spatial relations, site specific models for calculating mass balances of the deposits taking properties of the urban catchment areas into account, as well as geochemical fingerprinting using heavy metals and in-vitro video observations of the sedimentation dynamics of suspended solids in waste water.', 'Faulschlamm; Mischkanalisation; Regenüberläufe; Remobilisierung; Resuspension; Hochwasser; Schwermetalle; Quecksilber; Auenkontamination; Chemische Werke Buna']] | ['gnd:1058642758', 'gnd:4023025-9', 'gnd:4053964-7', 'gnd:4136932-4', 'gnd:4188657-4', 'gnd:4225643-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781231825'] | ['Winde, Frank', 'Halle (Saale)', 'Schwermetallbelastung', 'Schlamm', 'Vorfluter', 'Saaletal'] | Document
### Title: ['Schlammablagerungen in urbanen Vorflutern : Ursachen, Schwermetallbelastung und Remobilisierbarkeit untersucht an Vorflutern der Saaleaue bei Halle']
### Abstract:
[['sludge; combined stormwater-sewage drainage system; stormwater overflows; remobilisation; resuspension; flood; heavy metals; mercury; floodplain contamination; Chemische Werke Buna', 'Die Arbeit untersucht die Herkunft von starkmächtigen Faulschlammablagerungen in Nebenarmen der Saale die aufgrund hoher Quecksilbergehalte durch mehrere Gutachten als Folge von Abwassereinleitungen der chemischen Industrie oberhalb von Halle klassifiziert wurden. Ausgehend von der Fragestellung, ob es durch das ‚Jahrhunderthochwasser’ der Saale im April 1994 zur natürlichen Ausräumung der Schlämme gekommen ist, weist der Autor nach: a) daß dies nicht der Fall gewesen ist und auch nicht in Zukunft sein wird, b) daß die Schlämme nicht durch die Abwässer der stromaufwärtsliegenden chemischen Industrie entstanden sind, sondern durch niederschlagsbedingte Abwassereinleitungen aus dem überalterten Kanalisationsnetz. Dies wird u.a. mit Hilfe von detaillierten Kartierungen der Schlammmächtigkeit und ihrer Lagebeziehungen, standortspezifischen Modellen zur Massenbilianzierung der Schlämme unter Berücksichtigung der Eigenschaften der städtischen Einzugsgebiete, sowie geochemischem Fingerprinting mittels Schwermetallen und in-vitro Videobeobachtungen des Sedimentationsverhaltens abwasserbürtiger Schwebstoffe nachgewiesen.', 'The study investigates the origin of thick deposits of sludge accumulated in urban branches of the river Saale. Owing to high levels of mercury contained in the sludge previous studies identified upstream waste water discharges from the chemical industry as cause of the problem. Starting from the initial question whether the extreme flood of April 1994 naturally removed the sludge from the stream channel the author proves that a) this was not the case and will not happen in future; b) that the sludge was not caused by waste water from the upstream chemical industry but by rain-triggered combined stormwater-sewage discharges from an aged and overstretched municipal drainage system. This is based, among others, on detailed mapping of sludge thickness and associated analysis of spatial relations, site specific models for calculating mass balances of the deposits taking properties of the urban catchment areas into account, as well as geochemical fingerprinting using heavy metals and in-vitro video observations of the sedimentation dynamics of suspended solids in waste water.', 'Faulschlamm; Mischkanalisation; Regenüberläufe; Remobilisierung; Resuspension; Hochwasser; Schwermetalle; Quecksilber; Auenkontamination; Chemische Werke Buna']]
### GND ID:
['gnd:1058642758', 'gnd:4023025-9', 'gnd:4053964-7', 'gnd:4136932-4', 'gnd:4188657-4', 'gnd:4225643-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781231825']
### GND class:
['Winde, Frank', 'Halle (Saale)', 'Schwermetallbelastung', 'Schlamm', 'Vorfluter', 'Saaletal']
<|eot_id|> |
3A781300541.jsonld | ['Identifizierung differentieller Interaktionsmuster des Epidermalen Wachstumsfaktor-Rezeptors in Abhängigkeit von Arzneistoffresistenz und Rezeptorgenetik'] | [['Epidermaler Wachstumsfaktor-Rezeptor, Interaktom, Bioinformatik, globale Proteinanalyse, hochauflösende Proteomics, Proteinkomplexe, Systembiologie, Interactome, Bioinformatics, Global protein analysis, High resolution proteomics, Protein complexes, Systems biology', 'Growth, differentiation and survival of cells are regulated by a network of receptors and signaling pathways. If this network is out of balance, the cells can transform to tumor cells. The epidermal growth factor receptor (EGFR) is a driving force in this network and therefore a target of numerous anticancer agents. Due to extensive development of resistance, identification of responsible structures is important to synergistic degenerate aberrant signal cascades. After activation of EGFR, a signal-specific response is initiated by recruiting specific adapter proteins to the intracellular tyrosine kinase domain. The altered composition of the signaling proteins could reveal targets for new therapeutic approaches. To decipher the underlying mechanism, several proteomic studies have been applied to whole cell lysates. Despite the sensitivity of modern equipment, however, the identification of low abundant components in the proteome of a cell remains a challenge. The identification of differential protein patterns of the EGFR interactome as a function of resistance and receptor variant was the objective of this work. The EGFR with its interacting partners was precipitated from cell lysates. Subsequently, the proteins were separated by SDS-PAGE and analyzed with LC-MS/MS. From lysates of A431 cells, 183 proteins were detected in four bio replicates, including 15 direct interaction partners, such as GRB2, SHC1, SOS1/2, STAT1/3, AP2 and P85B. The calculation of the normalized ...']] | ['gnd:4076388-2', 'gnd:4271161-7', 'gnd:4596545-6', 'gnd:4611085-9', 'gnd:4798068-0', 'gnd:4809615-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781300541'] | ['Proteine', 'Epidermaler Wachstumsfaktor-Rezeptor', 'Proteomanalyse', 'Bioinformatik', 'Multiproteinkomplex', 'Systembiologie'] | Document
### Title: ['Identifizierung differentieller Interaktionsmuster des Epidermalen Wachstumsfaktor-Rezeptors in Abhängigkeit von Arzneistoffresistenz und Rezeptorgenetik']
### Abstract:
[['Epidermaler Wachstumsfaktor-Rezeptor, Interaktom, Bioinformatik, globale Proteinanalyse, hochauflösende Proteomics, Proteinkomplexe, Systembiologie, Interactome, Bioinformatics, Global protein analysis, High resolution proteomics, Protein complexes, Systems biology', 'Growth, differentiation and survival of cells are regulated by a network of receptors and signaling pathways. If this network is out of balance, the cells can transform to tumor cells. The epidermal growth factor receptor (EGFR) is a driving force in this network and therefore a target of numerous anticancer agents. Due to extensive development of resistance, identification of responsible structures is important to synergistic degenerate aberrant signal cascades. After activation of EGFR, a signal-specific response is initiated by recruiting specific adapter proteins to the intracellular tyrosine kinase domain. The altered composition of the signaling proteins could reveal targets for new therapeutic approaches. To decipher the underlying mechanism, several proteomic studies have been applied to whole cell lysates. Despite the sensitivity of modern equipment, however, the identification of low abundant components in the proteome of a cell remains a challenge. The identification of differential protein patterns of the EGFR interactome as a function of resistance and receptor variant was the objective of this work. The EGFR with its interacting partners was precipitated from cell lysates. Subsequently, the proteins were separated by SDS-PAGE and analyzed with LC-MS/MS. From lysates of A431 cells, 183 proteins were detected in four bio replicates, including 15 direct interaction partners, such as GRB2, SHC1, SOS1/2, STAT1/3, AP2 and P85B. The calculation of the normalized ...']]
### GND ID:
['gnd:4076388-2', 'gnd:4271161-7', 'gnd:4596545-6', 'gnd:4611085-9', 'gnd:4798068-0', 'gnd:4809615-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A781300541']
### GND class:
['Proteine', 'Epidermaler Wachstumsfaktor-Rezeptor', 'Proteomanalyse', 'Bioinformatik', 'Multiproteinkomplex', 'Systembiologie']
<|eot_id|> |
3A782104649.jsonld | ['English coordinate constructions : a processing perspective on constituent order'] | ['"Drawing on extensive corpus-based research, this book explores the nature and behavior of co-ordinate constructions in three cases studies, covering order in copulative compounds, binomials (bare phrases), and more complex phrases"--'] | ['gnd:1024634248', 'gnd:4014777-0', 'gnd:4165097-9', 'gnd:4206611-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782104649'] | ['Lohmann, Arne', 'Englisch', 'Konstruktion (Linguistik)', 'Koordination (Linguistik)'] | Document
### Title: ['English coordinate constructions : a processing perspective on constituent order']
### Abstract:
['"Drawing on extensive corpus-based research, this book explores the nature and behavior of co-ordinate constructions in three cases studies, covering order in copulative compounds, binomials (bare phrases), and more complex phrases"--']
### GND ID:
['gnd:1024634248', 'gnd:4014777-0', 'gnd:4165097-9', 'gnd:4206611-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782104649']
### GND class:
['Lohmann, Arne', 'Englisch', 'Konstruktion (Linguistik)', 'Koordination (Linguistik)']
<|eot_id|> |
3A782266088.jsonld | ['Silyliumionen und silylkationische Lewispaare'] | [['This thesis describes the syntheses and characterization of salts of triarylsilylium ions and of solvent complexes of trialkylsilylium ions. Here, a new synthetic pathway to triarylsilylium ions, starting from diarylmethylsilanes, was found and the mechanism was examined. The synthesized compounds were applied in the activation of dihydrogen (H2) und carbon dioxide (CO2). An electrophilic activation of CO2 and its derivatization to benzoic acid, formic acid or methanol are shown. Furthermore, the heterolytic cleavage of dihydrogen by the first silylcationic frustrated Lewis pair was examined. <engl.>', 'Diese Arbeit beschreibt die Synthese und Charakterisierung von Salzen der Triarylsilyliumionen und von Solvenzkomplexen der Trialkylsilyliumionen. Hierbei wurde ein neuer Syntheseweg für Triarylsilyliumionen, ausgehend von Diarylmethylsilanen, gefunden und mechanistisch untersucht. Die synthetisierten Verbindungen finden Einsatz in der Aktivierung von Diwasserstoff (H2) und Kohlenstoffdioxid (CO2). Es wird gezeigt, dass CO2 elektrophil aktiviert und zu Benzoesäure, Ameisensäure oder Methanol derivatisiert werden konnte. Zudem wurde die heterolytische Spaltung von Diwasserstoff durch das erste silylkationische frustrierte Lewispaar untersucht. <dt.>']] | ['gnd:1047638223', 'gnd:1126046434', 'gnd:4124194-0', 'gnd:4167502-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782266088'] | ['Schäfer, André', 'Beckhaus, Rüdiger', 'Siliciumverbindungen', 'Lewis-Addukt'] | Document
### Title: ['Silyliumionen und silylkationische Lewispaare']
### Abstract:
[['This thesis describes the syntheses and characterization of salts of triarylsilylium ions and of solvent complexes of trialkylsilylium ions. Here, a new synthetic pathway to triarylsilylium ions, starting from diarylmethylsilanes, was found and the mechanism was examined. The synthesized compounds were applied in the activation of dihydrogen (H2) und carbon dioxide (CO2). An electrophilic activation of CO2 and its derivatization to benzoic acid, formic acid or methanol are shown. Furthermore, the heterolytic cleavage of dihydrogen by the first silylcationic frustrated Lewis pair was examined. <engl.>', 'Diese Arbeit beschreibt die Synthese und Charakterisierung von Salzen der Triarylsilyliumionen und von Solvenzkomplexen der Trialkylsilyliumionen. Hierbei wurde ein neuer Syntheseweg für Triarylsilyliumionen, ausgehend von Diarylmethylsilanen, gefunden und mechanistisch untersucht. Die synthetisierten Verbindungen finden Einsatz in der Aktivierung von Diwasserstoff (H2) und Kohlenstoffdioxid (CO2). Es wird gezeigt, dass CO2 elektrophil aktiviert und zu Benzoesäure, Ameisensäure oder Methanol derivatisiert werden konnte. Zudem wurde die heterolytische Spaltung von Diwasserstoff durch das erste silylkationische frustrierte Lewispaar untersucht. <dt.>']]
### GND ID:
['gnd:1047638223', 'gnd:1126046434', 'gnd:4124194-0', 'gnd:4167502-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782266088']
### GND class:
['Schäfer, André', 'Beckhaus, Rüdiger', 'Siliciumverbindungen', 'Lewis-Addukt']
<|eot_id|> |
3A782266118.jsonld | ['Supporting route guidance of car drivers with a tactile display on urban roads'] | [['Visual and auditory displays complement each other in presenting turn-by-turn route information in conventional car navigation systems, but may results in driver’s distraction from the primary driving task.In this thesis, we present a tactile car navigation system, which displays turn-by-turn instructions with a vibro-tactile waist belt exploiting a "free" sensory channel. We investigated different tactile parameters such as intensity, duration, and rhythm and designed information presentations for different types of crossings along the route. In different evaluations on urban roads we compared our tactile design with existing car navigation systems measuring performance and cognitive workload of the driver. <engl.>', 'Konventionelle Navigationssysteme zeigen die Routeninformation sowohl visuell als auch akustisch über Richtungsangaben an. Dennoch können akustische und visuelle Reize den Fahrer vom Fahren ablenken und ein Sicherheitsrisiko darstellen. In dieser Dissertation werden Entwurf und Evaluation eines taktilen Navigationssystems vorgestellt, das Routeninformation mit einem vibro-taktilen Gürtel über den "freien" taktilen Sinneskanal kommuniziert. Es wurde untersucht, welche taktilen Parameter wie Intensität, Dauer aber auch Rhythmus sich für die Darstellung der Routeninformationen eigenen und Informationsdarstellungen für verschiedene städtische Kreuzungstypen entwickelt. In mehreren Experimenten in städtischen Umgebungen wurde das taktile Navigationssystem mit existierenden Navigationssystemen verglichen und dabei Performanz und die kognitive Belastung gemessen. <dt.>']] | ['gnd:1055858261', 'gnd:1128915472', 'gnd:4056783-7', 'gnd:4184494-4', 'gnd:4189371-2', 'gnd:4781185-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782266118'] | ['Asif, Amna', 'Boll, Susanne', 'Stadtverkehr', 'Tastwahrnehmung', 'Wegewahl', 'Navigationssystem'] | Document
### Title: ['Supporting route guidance of car drivers with a tactile display on urban roads']
### Abstract:
[['Visual and auditory displays complement each other in presenting turn-by-turn route information in conventional car navigation systems, but may results in driver’s distraction from the primary driving task.In this thesis, we present a tactile car navigation system, which displays turn-by-turn instructions with a vibro-tactile waist belt exploiting a "free" sensory channel. We investigated different tactile parameters such as intensity, duration, and rhythm and designed information presentations for different types of crossings along the route. In different evaluations on urban roads we compared our tactile design with existing car navigation systems measuring performance and cognitive workload of the driver. <engl.>', 'Konventionelle Navigationssysteme zeigen die Routeninformation sowohl visuell als auch akustisch über Richtungsangaben an. Dennoch können akustische und visuelle Reize den Fahrer vom Fahren ablenken und ein Sicherheitsrisiko darstellen. In dieser Dissertation werden Entwurf und Evaluation eines taktilen Navigationssystems vorgestellt, das Routeninformation mit einem vibro-taktilen Gürtel über den "freien" taktilen Sinneskanal kommuniziert. Es wurde untersucht, welche taktilen Parameter wie Intensität, Dauer aber auch Rhythmus sich für die Darstellung der Routeninformationen eigenen und Informationsdarstellungen für verschiedene städtische Kreuzungstypen entwickelt. In mehreren Experimenten in städtischen Umgebungen wurde das taktile Navigationssystem mit existierenden Navigationssystemen verglichen und dabei Performanz und die kognitive Belastung gemessen. <dt.>']]
### GND ID:
['gnd:1055858261', 'gnd:1128915472', 'gnd:4056783-7', 'gnd:4184494-4', 'gnd:4189371-2', 'gnd:4781185-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782266118']
### GND class:
['Asif, Amna', 'Boll, Susanne', 'Stadtverkehr', 'Tastwahrnehmung', 'Wegewahl', 'Navigationssystem']
<|eot_id|> |
3A782348068.jsonld | ['Religion and society in ancient Thessaly'] | ["The fertile plains of the ancient Greek region of Thessaly stretch south from the shadow of Mount Olympus. Thessaly's numerous small cities were home to some of the richest men in Greece, their fabulous wealth counted in innumerable flocks and slaves. It had a strict oligarchic government and a reputation for indulgence and witchcraft, but also a dominant position between Olympus and Delphi, and a claim to some of the greatest Greek heroes, such as Achilles himself. It can be viewed as both the cradle of many aspects of Greek civilization and as a challenge to the dominant image of ancient Greece as moderate, rational, and democratic.0This book explores the issues of regionalism in ancient Greek religion and the relationship between religion and society, as well as the problem of thinking about these matters through particular bodies of evidence. It discusses in depth the importance of citizenship and of other group-identities in Thessaly, and the relationship between cult activity and political and social organization. The volume investigates the Thessalian particularities of the evidence and the role of religion in giving the inhabitants of this land a sense of their identity and place in the wider Greek world, as well as the role of Thessaly in the ancients' and moderns' understanding of Greekness"] | ['gnd:1066661332', 'gnd:4001480-0', 'gnd:4049396-9', 'gnd:4059850-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782348068'] | ['Mili, Maria', 'Altertum', 'Religion', 'Thessalien'] | Document
### Title: ['Religion and society in ancient Thessaly']
### Abstract:
["The fertile plains of the ancient Greek region of Thessaly stretch south from the shadow of Mount Olympus. Thessaly's numerous small cities were home to some of the richest men in Greece, their fabulous wealth counted in innumerable flocks and slaves. It had a strict oligarchic government and a reputation for indulgence and witchcraft, but also a dominant position between Olympus and Delphi, and a claim to some of the greatest Greek heroes, such as Achilles himself. It can be viewed as both the cradle of many aspects of Greek civilization and as a challenge to the dominant image of ancient Greece as moderate, rational, and democratic.0This book explores the issues of regionalism in ancient Greek religion and the relationship between religion and society, as well as the problem of thinking about these matters through particular bodies of evidence. It discusses in depth the importance of citizenship and of other group-identities in Thessaly, and the relationship between cult activity and political and social organization. The volume investigates the Thessalian particularities of the evidence and the role of religion in giving the inhabitants of this land a sense of their identity and place in the wider Greek world, as well as the role of Thessaly in the ancients' and moderns' understanding of Greekness"]
### GND ID:
['gnd:1066661332', 'gnd:4001480-0', 'gnd:4049396-9', 'gnd:4059850-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782348068']
### GND class:
['Mili, Maria', 'Altertum', 'Religion', 'Thessalien']
<|eot_id|> |
3A782628125.jsonld | ['"I am because you are" : relationality in the works of Siri Hustvedt'] | ['"I am because you are" is a key passage in \'What I Loved\' (2003), contemporary American writer Siri Hustvedt\'s third novel, and a recurring motif throughout both her fictional and nonfictional work. This volume examines relational identity formation in her writing, especially the relationship between self and other in photography and painting, the transgression of corporeal boundaries in hysteria and anorexia, and the effects of losing attachment figures on personal identity. Hustvedt reveals identity as a complex product of conscious and unconscious interconnections within the social and biol'] | ['gnd:115468943', 'gnd:143547755', 'gnd:4311101-4', 'gnd:4391329-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782628125'] | ['Hustvedt, Siri 1955', 'Marks, Christine', 'Identität (Motiv)', 'Beziehung (Motiv)'] | Document
### Title: ['"I am because you are" : relationality in the works of Siri Hustvedt']
### Abstract:
['"I am because you are" is a key passage in \'What I Loved\' (2003), contemporary American writer Siri Hustvedt\'s third novel, and a recurring motif throughout both her fictional and nonfictional work. This volume examines relational identity formation in her writing, especially the relationship between self and other in photography and painting, the transgression of corporeal boundaries in hysteria and anorexia, and the effects of losing attachment figures on personal identity. Hustvedt reveals identity as a complex product of conscious and unconscious interconnections within the social and biol']
### GND ID:
['gnd:115468943', 'gnd:143547755', 'gnd:4311101-4', 'gnd:4391329-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782628125']
### GND class:
['Hustvedt, Siri 1955', 'Marks, Christine', 'Identität (Motiv)', 'Beziehung (Motiv)']
<|eot_id|> |
3A782718248.jsonld | ['Zur Berechnung von Mordell-Weil-Basen elliptischer Kurven über globalen Funktionenkörpern'] | [['This thesis deals with the computation of Mordell-Weil bases for an elliptic curve A over a global function field K with focus on the case char K = 2. In the first part explicit formulas for new descent maps and their images over completions of K are described. These local informations are combined to calculate the Selmer group which in turn yields upper bounds for the rank of A(K). The second part focuses on the algorithmic aspect. The running time is analyzed. Furthermore the thesis deals with the problems of both computing as well as minimizing and reducing models of genus one curves. It formulates statements about the height of points on A(K) which yield an infinite descent. Explicit bounds for the height of integral points on A(K) are computed. In the last part the algorithms are applied to a large number of relevant examples. <engl.>', 'Die Arbeit beschäftigt sich mit der Berechnung von Mordell-Weil-Basen für elliptische Kurven A über einem globalen Funktionenkörper K. Besonderes Interesse gilt dem Fall char K = 2. Im ersten Teil werden explizite Konstruktionen für Abstiegs-Abbildungen angegeben und ihre Bilder über Vervollständigungen beschrieben. Weiterhin untersucht die Arbeit, wie sich anhand der lokalen Informationen die Selmergruppe und Schranken für den Rang von A(K) berechnen lassen. Im zweiten Teil konzentriert sie sich auf den algorithmischen Aspekt. Neben Überlegungen zur Laufzeit beschäftigt sich die Arbeit mit der Berechnung sowie der Minimierung und Reduktion von Modellen für Kurven vom Geschlecht eins. Es werden Resultate über die Höhen von Punkten auf A(K) präsentiert. Sie ermöglichen einen unendlichen Abstieg. Es werden Schranken für die Höhe ganzer Punkte auf A(K) ermittelt und in verschiedenen Methoden verwendet. Im letzten Teil der Arbeit werden die Algorithmen auf relevante Beispiele angewendet. <dt.>']] | ['gnd:1056019190', 'gnd:11771822X', 'gnd:121599191', 'gnd:4001183-5', 'gnd:4014487-2', 'gnd:4155688-4', 'gnd:4215929-5', 'gnd:4769576-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782718248'] | ['Möhlmann, Gerriet', 'Pohst, Michael', 'Heß, Florian', 'Algorithmus', 'Elliptische Kurve', 'Funktionenkörper', 'Mordell-Weil-Theorem', 'Charakteristik p'] | Document
### Title: ['Zur Berechnung von Mordell-Weil-Basen elliptischer Kurven über globalen Funktionenkörpern']
### Abstract:
[['This thesis deals with the computation of Mordell-Weil bases for an elliptic curve A over a global function field K with focus on the case char K = 2. In the first part explicit formulas for new descent maps and their images over completions of K are described. These local informations are combined to calculate the Selmer group which in turn yields upper bounds for the rank of A(K). The second part focuses on the algorithmic aspect. The running time is analyzed. Furthermore the thesis deals with the problems of both computing as well as minimizing and reducing models of genus one curves. It formulates statements about the height of points on A(K) which yield an infinite descent. Explicit bounds for the height of integral points on A(K) are computed. In the last part the algorithms are applied to a large number of relevant examples. <engl.>', 'Die Arbeit beschäftigt sich mit der Berechnung von Mordell-Weil-Basen für elliptische Kurven A über einem globalen Funktionenkörper K. Besonderes Interesse gilt dem Fall char K = 2. Im ersten Teil werden explizite Konstruktionen für Abstiegs-Abbildungen angegeben und ihre Bilder über Vervollständigungen beschrieben. Weiterhin untersucht die Arbeit, wie sich anhand der lokalen Informationen die Selmergruppe und Schranken für den Rang von A(K) berechnen lassen. Im zweiten Teil konzentriert sie sich auf den algorithmischen Aspekt. Neben Überlegungen zur Laufzeit beschäftigt sich die Arbeit mit der Berechnung sowie der Minimierung und Reduktion von Modellen für Kurven vom Geschlecht eins. Es werden Resultate über die Höhen von Punkten auf A(K) präsentiert. Sie ermöglichen einen unendlichen Abstieg. Es werden Schranken für die Höhe ganzer Punkte auf A(K) ermittelt und in verschiedenen Methoden verwendet. Im letzten Teil der Arbeit werden die Algorithmen auf relevante Beispiele angewendet. <dt.>']]
### GND ID:
['gnd:1056019190', 'gnd:11771822X', 'gnd:121599191', 'gnd:4001183-5', 'gnd:4014487-2', 'gnd:4155688-4', 'gnd:4215929-5', 'gnd:4769576-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782718248']
### GND class:
['Möhlmann, Gerriet', 'Pohst, Michael', 'Heß, Florian', 'Algorithmus', 'Elliptische Kurve', 'Funktionenkörper', 'Mordell-Weil-Theorem', 'Charakteristik p']
<|eot_id|> |
3A782781004.jsonld | ['Noun phrase complexity in English'] | ['"This book explores noun phrase complexity in English, showing that it is best accounted for both by a linear and a hierarchical parameter: its length and its type of postmodifier(s). The study is methodologically unique in that it combines univariate and multivariate analyses in an investigation of four different syntactic variables. Drawing on more than three billion words of British and American data, Eva Berlage shows that the length and the structure of the NPs, along with language-external factors such as the regional variety of English, work as powerful determinants of the variation. On a theoretical level, the book reveals that the structural complexity of NPs cannot be sufficiently captured by (phrasal) node counts but that we need to incorporate the degree to which NPs are sentential. The book is designed for researchers and students interested in syntax, language variation, sociolinguistics, structural complexity and the history of English"--'] | ['gnd:1044264411', 'gnd:4014777-0', 'gnd:4120810-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782781004'] | ['Berlage, Eva', 'Englisch', 'Nominalphrase'] | Document
### Title: ['Noun phrase complexity in English']
### Abstract:
['"This book explores noun phrase complexity in English, showing that it is best accounted for both by a linear and a hierarchical parameter: its length and its type of postmodifier(s). The study is methodologically unique in that it combines univariate and multivariate analyses in an investigation of four different syntactic variables. Drawing on more than three billion words of British and American data, Eva Berlage shows that the length and the structure of the NPs, along with language-external factors such as the regional variety of English, work as powerful determinants of the variation. On a theoretical level, the book reveals that the structural complexity of NPs cannot be sufficiently captured by (phrasal) node counts but that we need to incorporate the degree to which NPs are sentential. The book is designed for researchers and students interested in syntax, language variation, sociolinguistics, structural complexity and the history of English"--']
### GND ID:
['gnd:1044264411', 'gnd:4014777-0', 'gnd:4120810-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782781004']
### GND class:
['Berlage, Eva', 'Englisch', 'Nominalphrase']
<|eot_id|> |
3A782845541.jsonld | ['On irreducible symplectic varieties of K3 [n]-type'] | ['Irreduzible symplektische Mannigfaltigkeiten, Modulräume, Komponenten. - Irreducible symplectic manifolds, moduli spaces, components'] | ['gnd:105364129X', 'gnd:4183462-8', 'gnd:4290704-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782845541'] | ['Apostolov, Apostol D.', 'Modulraum', 'Symplektische Mannigfaltigkeit'] | Document
### Title: ['On irreducible symplectic varieties of K3 [n]-type']
### Abstract:
['Irreduzible symplektische Mannigfaltigkeiten, Modulräume, Komponenten. - Irreducible symplectic manifolds, moduli spaces, components']
### GND ID:
['gnd:105364129X', 'gnd:4183462-8', 'gnd:4290704-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782845541']
### GND class:
['Apostolov, Apostol D.', 'Modulraum', 'Symplektische Mannigfaltigkeit']
<|eot_id|> |
3A782968864.jsonld | ['Laser link acquisition for the GRACE follow-on laser ranging interferometer'] | ['GRACE follow-on, laser link acquisition, mode expansion method. - Laser Link Akquisition, Modenzerlegung'] | ['gnd:1053737033', 'gnd:4136498-3', 'gnd:4159732-1', 'gnd:4166807-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782968864'] | ['Mahrdt, Christoph', 'Satellit', 'Heterodynspektroskopie', 'Laserinterferometrie'] | Document
### Title: ['Laser link acquisition for the GRACE follow-on laser ranging interferometer']
### Abstract:
['GRACE follow-on, laser link acquisition, mode expansion method. - Laser Link Akquisition, Modenzerlegung']
### GND ID:
['gnd:1053737033', 'gnd:4136498-3', 'gnd:4159732-1', 'gnd:4166807-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782968864']
### GND class:
['Mahrdt, Christoph', 'Satellit', 'Heterodynspektroskopie', 'Laserinterferometrie']
<|eot_id|> |
3A782973361.jsonld | ['Untersuchung des pUL31- und pUL34-unabhängigen Kernaustritts des Pseudorabies Virus'] | [['The nuclear egress of nucleocapsids is an essential step in the herpesviral replication cycle. Due to its size, the capsid cannot exit the nucleus through the nuclear pores, but instead is transported through the nuclear membrane. The viral proteins pUL34 and pUL31 form the nuclear egress complex (NEC), which recruits cellular and viral kinases to the nuclear membrane. There they phosphorylate lamins, which results in the local dissolution of the nuclear lamina and allows access of the nucleocapsids to the nuclear membrane. Deletion of one or both components of the NEC causes a significant reduction in viral titers but even in absence of the NEC, a few infectious virions are produced, which were used for reversion analysis. Therefore, first the UL34-negative and later also the UL31-negative PrV were passaged on rabbit kidney cells (RK13) until titers in the supernatant were similar to PrV-wildtype. From this supernatant single plaques were picked. These viruses replicated efficiently in the absence of the NEC and were designated as PrV-?UL34Pass and PrV-?UL31Pass, respectively. Ultrastructural analysis showed that the passaged viruses were not transported through the nuclear membrane like PrV-wildtype but through a fragmented nuclear envelope thereby releasing nucleocapsids into the cytosol. The aim of this study was to examine how nuclear egress functions without the NEC. In order to identify the mutated viral proteins which are important for nuclear envelope breakdown ...', 'Herpesvirus, Pseudorabies Virus, Fragmentierung der Kernmembran, Passagieren, ERK-Signalkaskade, nuclear envelope breakdown']] | ['gnd:1049990048', 'gnd:4155138-2', 'gnd:4159627-4', 'gnd:4307817-5', 'gnd:4309987-7', 'gnd:4409935-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782973361'] | ['Schulz, Katharina Stephanie', 'Fragmentierung', 'Herpesviren', 'Herpesvirus suis', 'Kernhülle', 'Signalkette'] | Document
### Title: ['Untersuchung des pUL31- und pUL34-unabhängigen Kernaustritts des Pseudorabies Virus']
### Abstract:
[['The nuclear egress of nucleocapsids is an essential step in the herpesviral replication cycle. Due to its size, the capsid cannot exit the nucleus through the nuclear pores, but instead is transported through the nuclear membrane. The viral proteins pUL34 and pUL31 form the nuclear egress complex (NEC), which recruits cellular and viral kinases to the nuclear membrane. There they phosphorylate lamins, which results in the local dissolution of the nuclear lamina and allows access of the nucleocapsids to the nuclear membrane. Deletion of one or both components of the NEC causes a significant reduction in viral titers but even in absence of the NEC, a few infectious virions are produced, which were used for reversion analysis. Therefore, first the UL34-negative and later also the UL31-negative PrV were passaged on rabbit kidney cells (RK13) until titers in the supernatant were similar to PrV-wildtype. From this supernatant single plaques were picked. These viruses replicated efficiently in the absence of the NEC and were designated as PrV-?UL34Pass and PrV-?UL31Pass, respectively. Ultrastructural analysis showed that the passaged viruses were not transported through the nuclear membrane like PrV-wildtype but through a fragmented nuclear envelope thereby releasing nucleocapsids into the cytosol. The aim of this study was to examine how nuclear egress functions without the NEC. In order to identify the mutated viral proteins which are important for nuclear envelope breakdown ...', 'Herpesvirus, Pseudorabies Virus, Fragmentierung der Kernmembran, Passagieren, ERK-Signalkaskade, nuclear envelope breakdown']]
### GND ID:
['gnd:1049990048', 'gnd:4155138-2', 'gnd:4159627-4', 'gnd:4307817-5', 'gnd:4309987-7', 'gnd:4409935-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A782973361']
### GND class:
['Schulz, Katharina Stephanie', 'Fragmentierung', 'Herpesviren', 'Herpesvirus suis', 'Kernhülle', 'Signalkette']
<|eot_id|> |
3A783616260.jsonld | ["Designing Tito's capital : urban planning, modernism, and socialism"] | ['"The devastation of World War II left the Yugoslavian capital of Belgrade in ruins. Communist Party leader Josip Broz Tito saw this as a golden opportunity to recreate the city through his vision of socialism. In Designing Tito\'s Capital, Brigitte Le Normand analyzes the unprecedented planning process called for by the new leader, and the determination of planners to create an urban environment that would benefit all citizens."--'] | ['gnd:1058254480', 'gnd:4002851-3', 'gnd:4005411-1', 'gnd:4055785-6', 'gnd:4056754-0', 'gnd:4056795-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783616260'] | ['Le Normand, Brigitte', 'Architektur', 'Belgrad', 'Sozialismus', 'Stadtplanung', 'Städtebau'] | Document
### Title: ["Designing Tito's capital : urban planning, modernism, and socialism"]
### Abstract:
['"The devastation of World War II left the Yugoslavian capital of Belgrade in ruins. Communist Party leader Josip Broz Tito saw this as a golden opportunity to recreate the city through his vision of socialism. In Designing Tito\'s Capital, Brigitte Le Normand analyzes the unprecedented planning process called for by the new leader, and the determination of planners to create an urban environment that would benefit all citizens."--']
### GND ID:
['gnd:1058254480', 'gnd:4002851-3', 'gnd:4005411-1', 'gnd:4055785-6', 'gnd:4056754-0', 'gnd:4056795-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783616260']
### GND class:
['Le Normand, Brigitte', 'Architektur', 'Belgrad', 'Sozialismus', 'Stadtplanung', 'Städtebau']
<|eot_id|> |
3A78371341X.jsonld | ['Schnelle Wegsucheverfahren auf digitalen Straßenkarten -- Entwicklung, Implementierung und Anwendungsbeispiel bei einem Logistikdienstleister'] | [["The solution to many real-world transportation planning problems is combinatorially comprehensive, complex, and some of the necessary information is not available in a sufficiently structured form. Hence, standard solving methods are often not applicable. This holds for courier and express providers' operational dispatching, where vehicles are assigned to customer orders. Typically, dialog-oriented decision support systems (DSS) are used to generate recommendations from which a human dispatcher selects the most profitable one by means of domain-specific knowledge. In this process, solutions that consolidate the freight of multiple customer orders onto a single vehicle are usually particularly favorable. This work examines optimization of the dispatching process with particular attention to the potential of freight consolidation. In order to uncover possible savings by consolidating, many alternative vehicle routes need to be determined and compared with each other. For this purpose, fast routing algorithms are essential. These algorithms form the first focus of this work. Based on a comparative literature overview of classical'' as well as current routing algorithms, the center of attention is put on contraction hierarchies (CH) as they provide a particularly favorable ratio of query speed-up to additional memory requirement. Both optimizations of hierarchy creation and new enhancements for queries in CH are studied. The considerable merits of these approaches are empirically shown through extensive benchmarks on digital road maps provided by the OpenStreetMap project. More realistic routes are obtained when routing algorithms take turn restrictions into account. First, common approaches from literature are presented for this purpose. Next, the adaptive search is introduced as a more efficient new approach, and adjusted for usage in CH. The above-mentioned query enhancements can easily be applied to this method. The advantages of the adaptive search in CH over the edge-based search that is employed for turn restriction aware routing in earlier literature is emphasized by further benchmarks. For the second focus of this work --~the vehicle routing problem with freight consolidation~-- first, a thorough mathematical model is developed. Next, model assumptions are extracted from past operational real-world data provided by IN tIME Express Logistik GmbH. Eventually, the recursive savings algorithm is introduced as a heuristic that can generate freight consolidation recommendations in the context of a DSS. Employed in multiple benchmarks based upon the past operational data, it reveals considerable cost savings compared to former dispatching decisions.", 'Die Lösung vieler straßengebundener Transportplanungsprobleme aus der Praxis ist kombinatorisch aufwendig, komplex und manche der notwendigen Informationen liegen nicht hinreichend strukturiert vor. Standard-Lösungsverfahren sind daher für sie oft ungeeignet. Dies gilt auch für die operative Disposition bei Express- und Direkt-Kurierdienstleistern, bei der Entscheidungen über die Zuweisung von Fahrzeugen zu Aufträgen getroffen werden. Üblicherweise kommen für diese Aufgabe dialogorientierte Entscheidungsunterstützungssysteme (EUS) zum Einsatz, welche Vorschläge generieren, aus denen menschliche Disponenten unter Einbezug von domänenspezifischem Wissen den günstigsten auswählen. Lösungen, bei denen die Frachten mehrerer Aufträge auf einem Fahrzeug konsolidiert werden, sind dabei häufig besonders wirtschaftlich. Diese Arbeit beschäftigt sich mit der Optimierung der Disposition im Hinblick auf das Konsolidierungspotential der Frachten. Zum Aufdecken möglicher Ersparnisse durch Konsolidierung müssen viele alternative Fahrzeugrouten ermittelt und verglichen werden. Hierfür sind schnelle Verfahren zur Wegsuche von zentraler Bedeutung. Diese Verfahren bilden den ersten Schwerpunkt der Arbeit. Aufbauend auf einem vergleichenden Überblick "klassischer"\' sowie aktueller Wegsucheverfahren wird mit den Contraction Hierarchies (CH) ein hierarchisches Verfahren in den Mittelpunkt gestellt, das ein besonders vorteilhaftes Verhältnis von Suchgeschwindigkeit zu benötigtem Speicherbedarf aufweist. Untersucht werden Optimierungen der Hierarchie-Erzeugung sowie neue Erweiterungen der Wegsuche in CH. In ausführlichen Benchmarks auf digitalen Straßenkarten des OpenStreetMap-Projekts werden die deutlichen Verbesserungen durch diese Erweiterungen empirisch nachgewiesen. Eine größere Realitätsnähe der berechneten Routen ergibt sich durch die Berücksichtigung von Abbiegebeschränkungen bei der Wegsuche. Nach der Vorstellung der in der Literatur hierfür üblichen Ansätze wird mit der adaptiven Wegsuche ein leistungsstarkes neues Verfahren für diesen Zweck präsentiert und für den Einsatz in CH angepasst. Die oben genannten Erweiterungen der Wegsuche sind mühelos auf dieses Verfahren übertragbar. Weitere Benchmarks unterstreichen die Vorteile der adaptiven gegenüber der in früherer Literatur eingesetzten pfeilbasierten Suche nach Wegen mit Abbiegebeschränkungen in CH. Für den zweiten Schwerpunkt der Arbeit, das Konsolidierungsproblem, wird zunächst ein ausführliches mathematisches Modell entwickelt. Es folgt eine Extraktion realitätsnaher Modellannahmen aus operativen Vergangenheitsdaten der IN tIME Express Logistik GmbH. Mit dem rekursiven Savingsverfahren wird schließlich eine neue Heuristik präsentiert, die es ermöglicht, Konsolidierungsvorschläge im Rahmen eines EUS zu generieren. Sie offenbart in mehreren, auf den Vergangenheitsdaten basierenden Benchmarks ein deutliches Kosteneinsparungspotential gegenüber früheren Dispositionsentscheidungen.']] | ['gnd:4511937-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78371341X'] | ['Online-Ressource'] | Document
### Title: ['Schnelle Wegsucheverfahren auf digitalen Straßenkarten -- Entwicklung, Implementierung und Anwendungsbeispiel bei einem Logistikdienstleister']
### Abstract:
[["The solution to many real-world transportation planning problems is combinatorially comprehensive, complex, and some of the necessary information is not available in a sufficiently structured form. Hence, standard solving methods are often not applicable. This holds for courier and express providers' operational dispatching, where vehicles are assigned to customer orders. Typically, dialog-oriented decision support systems (DSS) are used to generate recommendations from which a human dispatcher selects the most profitable one by means of domain-specific knowledge. In this process, solutions that consolidate the freight of multiple customer orders onto a single vehicle are usually particularly favorable. This work examines optimization of the dispatching process with particular attention to the potential of freight consolidation. In order to uncover possible savings by consolidating, many alternative vehicle routes need to be determined and compared with each other. For this purpose, fast routing algorithms are essential. These algorithms form the first focus of this work. Based on a comparative literature overview of classical'' as well as current routing algorithms, the center of attention is put on contraction hierarchies (CH) as they provide a particularly favorable ratio of query speed-up to additional memory requirement. Both optimizations of hierarchy creation and new enhancements for queries in CH are studied. The considerable merits of these approaches are empirically shown through extensive benchmarks on digital road maps provided by the OpenStreetMap project. More realistic routes are obtained when routing algorithms take turn restrictions into account. First, common approaches from literature are presented for this purpose. Next, the adaptive search is introduced as a more efficient new approach, and adjusted for usage in CH. The above-mentioned query enhancements can easily be applied to this method. The advantages of the adaptive search in CH over the edge-based search that is employed for turn restriction aware routing in earlier literature is emphasized by further benchmarks. For the second focus of this work --~the vehicle routing problem with freight consolidation~-- first, a thorough mathematical model is developed. Next, model assumptions are extracted from past operational real-world data provided by IN tIME Express Logistik GmbH. Eventually, the recursive savings algorithm is introduced as a heuristic that can generate freight consolidation recommendations in the context of a DSS. Employed in multiple benchmarks based upon the past operational data, it reveals considerable cost savings compared to former dispatching decisions.", 'Die Lösung vieler straßengebundener Transportplanungsprobleme aus der Praxis ist kombinatorisch aufwendig, komplex und manche der notwendigen Informationen liegen nicht hinreichend strukturiert vor. Standard-Lösungsverfahren sind daher für sie oft ungeeignet. Dies gilt auch für die operative Disposition bei Express- und Direkt-Kurierdienstleistern, bei der Entscheidungen über die Zuweisung von Fahrzeugen zu Aufträgen getroffen werden. Üblicherweise kommen für diese Aufgabe dialogorientierte Entscheidungsunterstützungssysteme (EUS) zum Einsatz, welche Vorschläge generieren, aus denen menschliche Disponenten unter Einbezug von domänenspezifischem Wissen den günstigsten auswählen. Lösungen, bei denen die Frachten mehrerer Aufträge auf einem Fahrzeug konsolidiert werden, sind dabei häufig besonders wirtschaftlich. Diese Arbeit beschäftigt sich mit der Optimierung der Disposition im Hinblick auf das Konsolidierungspotential der Frachten. Zum Aufdecken möglicher Ersparnisse durch Konsolidierung müssen viele alternative Fahrzeugrouten ermittelt und verglichen werden. Hierfür sind schnelle Verfahren zur Wegsuche von zentraler Bedeutung. Diese Verfahren bilden den ersten Schwerpunkt der Arbeit. Aufbauend auf einem vergleichenden Überblick "klassischer"\' sowie aktueller Wegsucheverfahren wird mit den Contraction Hierarchies (CH) ein hierarchisches Verfahren in den Mittelpunkt gestellt, das ein besonders vorteilhaftes Verhältnis von Suchgeschwindigkeit zu benötigtem Speicherbedarf aufweist. Untersucht werden Optimierungen der Hierarchie-Erzeugung sowie neue Erweiterungen der Wegsuche in CH. In ausführlichen Benchmarks auf digitalen Straßenkarten des OpenStreetMap-Projekts werden die deutlichen Verbesserungen durch diese Erweiterungen empirisch nachgewiesen. Eine größere Realitätsnähe der berechneten Routen ergibt sich durch die Berücksichtigung von Abbiegebeschränkungen bei der Wegsuche. Nach der Vorstellung der in der Literatur hierfür üblichen Ansätze wird mit der adaptiven Wegsuche ein leistungsstarkes neues Verfahren für diesen Zweck präsentiert und für den Einsatz in CH angepasst. Die oben genannten Erweiterungen der Wegsuche sind mühelos auf dieses Verfahren übertragbar. Weitere Benchmarks unterstreichen die Vorteile der adaptiven gegenüber der in früherer Literatur eingesetzten pfeilbasierten Suche nach Wegen mit Abbiegebeschränkungen in CH. Für den zweiten Schwerpunkt der Arbeit, das Konsolidierungsproblem, wird zunächst ein ausführliches mathematisches Modell entwickelt. Es folgt eine Extraktion realitätsnaher Modellannahmen aus operativen Vergangenheitsdaten der IN tIME Express Logistik GmbH. Mit dem rekursiven Savingsverfahren wird schließlich eine neue Heuristik präsentiert, die es ermöglicht, Konsolidierungsvorschläge im Rahmen eines EUS zu generieren. Sie offenbart in mehreren, auf den Vergangenheitsdaten basierenden Benchmarks ein deutliches Kosteneinsparungspotential gegenüber früheren Dispositionsentscheidungen.']]
### GND ID:
['gnd:4511937-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78371341X']
### GND class:
['Online-Ressource']
<|eot_id|> |
3A783954476.jsonld | ['Entwicklung von Lebendzell-Microarrays und ihre Anwendung in der Detektion klinisch relevanter Biomarker'] | ['Lebendzell-Microarrays, Quantum Dots, Antikörper, Aptamere, spezifische Zelldetektion/-diskriminierung. - Living cell microarrays, antibodies, aptamers, specific cell detection/discrimination'] | ['gnd:1051891191', 'gnd:4128704-6', 'gnd:4425928-1', 'gnd:4441960-0', 'gnd:4544227-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783954476'] | ['Bongartz, Rebecca', 'Krebszelle', 'Biomarker', 'Aptamer', 'Microarray'] | Document
### Title: ['Entwicklung von Lebendzell-Microarrays und ihre Anwendung in der Detektion klinisch relevanter Biomarker']
### Abstract:
['Lebendzell-Microarrays, Quantum Dots, Antikörper, Aptamere, spezifische Zelldetektion/-diskriminierung. - Living cell microarrays, antibodies, aptamers, specific cell detection/discrimination']
### GND ID:
['gnd:1051891191', 'gnd:4128704-6', 'gnd:4425928-1', 'gnd:4441960-0', 'gnd:4544227-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783954476']
### GND class:
['Bongartz, Rebecca', 'Krebszelle', 'Biomarker', 'Aptamer', 'Microarray']
<|eot_id|> |
3A783976682.jsonld | ['Bridging the gap between precise RT-level power/timing estimation and fast high-level simulation : a method for automatically identifying and characterising combinational macros in synchronous sequential systems at register-transfer level and subsequent executable high-level model generation with respect to non-functional properties'] | [['This thesis tackles the problem of a fast, yet accurate power and timing estimation of embedded HW modules at a high-level of abstraction. By augmenting an executable high-level model with accurate power and timing information, fast and comprehensive simulations at a high-level of abstraction become possible. Using HLS, a behavioural system description is transformed into a cycle-accurate description at RTL. Combinational macros are identified and characterised automatically, using sophisticated RT-level power models. These provide accurate estimates, while considering as many relevant physical properties and synthesis artefacts as possible. A power and timing annotated high-level simulation model is then generated. This virtual prototype allows a fast, yet accurate estimation of the design. The generated prototype can also be embedded into a virtual system prototype allowing a DSE, far more complex and comprehensive than would be feasible before. Evaluation results show that by having an average relative error per cycle of less than 6.93% and a total error of around 1%, a speed-up of 160x is archived, while giving nearly cycle-accurate estimates. <engl.>', 'Diese Arbeit adressiert das Problem schneller aber dennoch genauer Abschätzungen des zeitlichen Verhaltens eingebetteter HW Module sowie deren Verlustleistung. Durch anreichern einer ausführbaren High-Level-Beschreibung mit Power und Timing Informationen werden schnelle Simulationen auf hoher Abstraktionsebene möglich. Mittels einer HLS wird eine Verhaltensbeschreibung in eine taktgenaue RTL-Beschreibung transformiert. Kombinatorische Makros werden automatisch identifiziert und mit Hilfe fortschrittlicher RTL Power-Modelle charakterisiert. Ein um Power und Timing angereichertes high-level Simulationsmodell wird daraus erzeugt. Dieser virtuelle Prototyp erlaubt eine schnelle, aber dennoch genaue Abschätzung des Designs. Der Prototyp kann ebenfalls in einen virtuellen Systemprototypen eingebunden werden. Dies erlaubt eine deutlich komplexere und umfassendere DSE als vorher möglich war. Die Evaluationsergebnisse zeigen, dass bei einem relativen Fehler je Takt von weniger als 6.93% und einem Gesamtfehler von ca. 1%, eine Beschleunigung von ca. 160x erreicht werden kann, bei gleichzeitig fast taktgenauen Ergebnissen. <dt.>']] | ['gnd:1056028246', 'gnd:17228242X', 'gnd:4170297-9', 'gnd:4187881-4', 'gnd:4304375-6', 'gnd:4312536-0', 'gnd:4348178-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783976682'] | ['Hylla, Kai', 'Nebel, Wolfgang', 'Modellierung', 'Verlustleistung', 'Abschätzung', 'Entwurfsautomation', 'Logiksynthese'] | Document
### Title: ['Bridging the gap between precise RT-level power/timing estimation and fast high-level simulation : a method for automatically identifying and characterising combinational macros in synchronous sequential systems at register-transfer level and subsequent executable high-level model generation with respect to non-functional properties']
### Abstract:
[['This thesis tackles the problem of a fast, yet accurate power and timing estimation of embedded HW modules at a high-level of abstraction. By augmenting an executable high-level model with accurate power and timing information, fast and comprehensive simulations at a high-level of abstraction become possible. Using HLS, a behavioural system description is transformed into a cycle-accurate description at RTL. Combinational macros are identified and characterised automatically, using sophisticated RT-level power models. These provide accurate estimates, while considering as many relevant physical properties and synthesis artefacts as possible. A power and timing annotated high-level simulation model is then generated. This virtual prototype allows a fast, yet accurate estimation of the design. The generated prototype can also be embedded into a virtual system prototype allowing a DSE, far more complex and comprehensive than would be feasible before. Evaluation results show that by having an average relative error per cycle of less than 6.93% and a total error of around 1%, a speed-up of 160x is archived, while giving nearly cycle-accurate estimates. <engl.>', 'Diese Arbeit adressiert das Problem schneller aber dennoch genauer Abschätzungen des zeitlichen Verhaltens eingebetteter HW Module sowie deren Verlustleistung. Durch anreichern einer ausführbaren High-Level-Beschreibung mit Power und Timing Informationen werden schnelle Simulationen auf hoher Abstraktionsebene möglich. Mittels einer HLS wird eine Verhaltensbeschreibung in eine taktgenaue RTL-Beschreibung transformiert. Kombinatorische Makros werden automatisch identifiziert und mit Hilfe fortschrittlicher RTL Power-Modelle charakterisiert. Ein um Power und Timing angereichertes high-level Simulationsmodell wird daraus erzeugt. Dieser virtuelle Prototyp erlaubt eine schnelle, aber dennoch genaue Abschätzung des Designs. Der Prototyp kann ebenfalls in einen virtuellen Systemprototypen eingebunden werden. Dies erlaubt eine deutlich komplexere und umfassendere DSE als vorher möglich war. Die Evaluationsergebnisse zeigen, dass bei einem relativen Fehler je Takt von weniger als 6.93% und einem Gesamtfehler von ca. 1%, eine Beschleunigung von ca. 160x erreicht werden kann, bei gleichzeitig fast taktgenauen Ergebnissen. <dt.>']]
### GND ID:
['gnd:1056028246', 'gnd:17228242X', 'gnd:4170297-9', 'gnd:4187881-4', 'gnd:4304375-6', 'gnd:4312536-0', 'gnd:4348178-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783976682']
### GND class:
['Hylla, Kai', 'Nebel, Wolfgang', 'Modellierung', 'Verlustleistung', 'Abschätzung', 'Entwurfsautomation', 'Logiksynthese']
<|eot_id|> |
3A783977646.jsonld | ['Revealing manduca sexta´s nicotine metabolism and its ecological consequences using plant mediated RNAi based reverse genetics'] | ['Insects have developed a myriad of adaptations to live and evolve. Manduca sexta, a specialist lepidopteran herbivore of Nicotiana attenuata, has developed a remarkable adaptation to tolerate a toxic alkaloid ‘nicotine’ that it ingests from its host plant Nicotiana attenuata. The mechanism of nicotine tolerance in M. sexta larvae is not completely known. In this work I used a reverse genetics based approach to silence M. sexta’s genes involved nicotine tolerance to understand their role and ecological consequences of nicotine adaptation by this insect. Nicotine induced midgut-based M. sexta CYP6B46 was silenced by plant-mediated RNAi. Survivorship of CYP6B46-silenced M. sexta larvae was found to be lowered, similar to that of low-nicotine-foliage feeding larvae in the field (Great Basin desert, Utah). While investigating the reasons for the reduced survivorship, I identified a native wolf-spider that preferred to prey on nicotine-free and CYP6B46-silenced larvae, compared to control larvae. ...'] | ['gnd:117599524X', 'gnd:1192684982', 'gnd:36164-1', 'gnd:4057699-1', 'gnd:4131089-5', 'gnd:4168777-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783977646'] | ['Kumar, Pavan', 'Heckel, David G.', 'Friedrich-Schiller-Universität Jena', 'Stoffwechsel', 'Nicotin', 'Manduca sexta'] | Document
### Title: ['Revealing manduca sexta´s nicotine metabolism and its ecological consequences using plant mediated RNAi based reverse genetics']
### Abstract:
['Insects have developed a myriad of adaptations to live and evolve. Manduca sexta, a specialist lepidopteran herbivore of Nicotiana attenuata, has developed a remarkable adaptation to tolerate a toxic alkaloid ‘nicotine’ that it ingests from its host plant Nicotiana attenuata. The mechanism of nicotine tolerance in M. sexta larvae is not completely known. In this work I used a reverse genetics based approach to silence M. sexta’s genes involved nicotine tolerance to understand their role and ecological consequences of nicotine adaptation by this insect. Nicotine induced midgut-based M. sexta CYP6B46 was silenced by plant-mediated RNAi. Survivorship of CYP6B46-silenced M. sexta larvae was found to be lowered, similar to that of low-nicotine-foliage feeding larvae in the field (Great Basin desert, Utah). While investigating the reasons for the reduced survivorship, I identified a native wolf-spider that preferred to prey on nicotine-free and CYP6B46-silenced larvae, compared to control larvae. ...']
### GND ID:
['gnd:117599524X', 'gnd:1192684982', 'gnd:36164-1', 'gnd:4057699-1', 'gnd:4131089-5', 'gnd:4168777-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A783977646']
### GND class:
['Kumar, Pavan', 'Heckel, David G.', 'Friedrich-Schiller-Universität Jena', 'Stoffwechsel', 'Nicotin', 'Manduca sexta']
<|eot_id|> |
3A784179875.jsonld | ['Multi-omics based characterization of various stress responses in Bacillus subtilis'] | [['Bacillus subtilis, Multi-omics, SRM (single reaction monitoring), Osmostress, Zentralkohlenstoffmetabolismus, Anpassungsreaktionen, Central carbon metabolism, adaptational responses', 'The soil bacterium Bacillus subtilis is capable of surviving most of the ensuing environmental stress conditions. The dynamic nature of the soil habitat is manifested with varying amounts of nutrients, frequent flooding, drying and variation of other growth parameters like temperature, acidity, aeration etc. In order to survive in these conditions, B. subtilis has evolved to employ very complex adaptational responses. These adaptational responses are often multi-faceted; hence comprehensive understanding of the adaptational responses requires generation and integration of data on multi-omics level. Hence, multi-omics based detailed analysis was performed for the molecules involved in the central carbon metabolism (CCM) and proline biosynthesis pathway. In the current study two major stress conditions were extensively investigated: 1) energy limitation/starvation which is achieved by limiting glucose in the growth medium, 2) osmostress resulting from frequent drying out of soil which is simulated by adding 1.2 M NaCl to the growth medium. In addition to osmostress, the naturally available osmoprotectant glycine betaine (GB) was supplemented to understand the simultaneous influence of osmostress and osmoprotection on cellular physiology. To measure absolute protein abundances by mass spectrometry, a targeted approach (SRM -single reaction monitoring) using stable heavy isotope labeled artificial standard proteins known as QconCATs was optimized and implemented in the current ...']] | ['gnd:4138565-2', 'gnd:4242465-3', 'gnd:4451425-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784179875'] | ['Stressreaktion', 'Heubacillus', 'Kohlenstoffstoffwechsel'] | Document
### Title: ['Multi-omics based characterization of various stress responses in Bacillus subtilis']
### Abstract:
[['Bacillus subtilis, Multi-omics, SRM (single reaction monitoring), Osmostress, Zentralkohlenstoffmetabolismus, Anpassungsreaktionen, Central carbon metabolism, adaptational responses', 'The soil bacterium Bacillus subtilis is capable of surviving most of the ensuing environmental stress conditions. The dynamic nature of the soil habitat is manifested with varying amounts of nutrients, frequent flooding, drying and variation of other growth parameters like temperature, acidity, aeration etc. In order to survive in these conditions, B. subtilis has evolved to employ very complex adaptational responses. These adaptational responses are often multi-faceted; hence comprehensive understanding of the adaptational responses requires generation and integration of data on multi-omics level. Hence, multi-omics based detailed analysis was performed for the molecules involved in the central carbon metabolism (CCM) and proline biosynthesis pathway. In the current study two major stress conditions were extensively investigated: 1) energy limitation/starvation which is achieved by limiting glucose in the growth medium, 2) osmostress resulting from frequent drying out of soil which is simulated by adding 1.2 M NaCl to the growth medium. In addition to osmostress, the naturally available osmoprotectant glycine betaine (GB) was supplemented to understand the simultaneous influence of osmostress and osmoprotection on cellular physiology. To measure absolute protein abundances by mass spectrometry, a targeted approach (SRM -single reaction monitoring) using stable heavy isotope labeled artificial standard proteins known as QconCATs was optimized and implemented in the current ...']]
### GND ID:
['gnd:4138565-2', 'gnd:4242465-3', 'gnd:4451425-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784179875']
### GND class:
['Stressreaktion', 'Heubacillus', 'Kohlenstoffstoffwechsel']
<|eot_id|> |
3A784803617.jsonld | ['Erfolgsversprechende Konfigurationen der Innovationsfähigkeiten in kleinen und mittelständischen Unternehmen'] | ['Freie Schlagworte: Innovationsmanagement, strategische Innovation, Business Development, Innovationsfähigkeit, Corporate Development. - Schlagworte Englisch: Innovation management, strategic innovation, business innovation'] | ['gnd:1051852730', 'gnd:4031031-0', 'gnd:4161817-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784803617'] | ['Seeger, Björn', 'Klein- und Mittelbetrieb', 'Innovationsmanagement'] | Document
### Title: ['Erfolgsversprechende Konfigurationen der Innovationsfähigkeiten in kleinen und mittelständischen Unternehmen']
### Abstract:
['Freie Schlagworte: Innovationsmanagement, strategische Innovation, Business Development, Innovationsfähigkeit, Corporate Development. - Schlagworte Englisch: Innovation management, strategic innovation, business innovation']
### GND ID:
['gnd:1051852730', 'gnd:4031031-0', 'gnd:4161817-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784803617']
### GND class:
['Seeger, Björn', 'Klein- und Mittelbetrieb', 'Innovationsmanagement']
<|eot_id|> |
3A784815461.jsonld | ['Reconstruction of Asian monsoon using compound-specific isotope signals of aquatic and terrestrial biomarkers in Tibetan lake systems'] | ['The general aim of this thesis was the reconstruction of the Indian Ocean summer monsoon (IOSM) dynamics using compound-specific isotope signals of aquatic and terrestrial biomarkers in Tibetan lake systems. Monsoon winds and precipitation can be retraced using different proxies, indirect climate indicators, which reflect the environmental factors in a known way. To assure the proper application of compound-specific δD values as monsoon proxy, the biological origin of sedimentary n-alkanes, their source waters and climatic relevant parameters influencing the δD values have been investigated at the Tibetan Plateau. Moreover, the utility of GDGTs as additional paleoclimate proxy for the Monsoon reconstruction has been analyzed. ...'] | ['gnd:1047326752', 'gnd:36164-1', 'gnd:4060036-1', 'gnd:4162584-5', 'gnd:4202863-2', 'gnd:4425928-1', 'gnd:4466086-8', 'gnd:4654440-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784815461'] | ['Günther, Franziska', 'Friedrich-Schiller-Universität Jena', 'Tibet', 'Isotopenhäufigkeit', 'Allgemeine atmosphärische Zirkulation', 'Biomarker', 'Sommermonsun', 'Druckgradient'] | Document
### Title: ['Reconstruction of Asian monsoon using compound-specific isotope signals of aquatic and terrestrial biomarkers in Tibetan lake systems']
### Abstract:
['The general aim of this thesis was the reconstruction of the Indian Ocean summer monsoon (IOSM) dynamics using compound-specific isotope signals of aquatic and terrestrial biomarkers in Tibetan lake systems. Monsoon winds and precipitation can be retraced using different proxies, indirect climate indicators, which reflect the environmental factors in a known way. To assure the proper application of compound-specific δD values as monsoon proxy, the biological origin of sedimentary n-alkanes, their source waters and climatic relevant parameters influencing the δD values have been investigated at the Tibetan Plateau. Moreover, the utility of GDGTs as additional paleoclimate proxy for the Monsoon reconstruction has been analyzed. ...']
### GND ID:
['gnd:1047326752', 'gnd:36164-1', 'gnd:4060036-1', 'gnd:4162584-5', 'gnd:4202863-2', 'gnd:4425928-1', 'gnd:4466086-8', 'gnd:4654440-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A784815461']
### GND class:
['Günther, Franziska', 'Friedrich-Schiller-Universität Jena', 'Tibet', 'Isotopenhäufigkeit', 'Allgemeine atmosphärische Zirkulation', 'Biomarker', 'Sommermonsun', 'Druckgradient']
<|eot_id|> |
3A785261591.jsonld | ['Timing for outcrossing : circadian clock regulates floral rhythms with large fitness consequences'] | ['Like most organisms, plants need to keep a daily rhythm to synchronize their inner functions to the available energy and nutrients; even due to its sessile nature it’s especially important for a large group to find ways to reproduce by outcrossing. The endogenous clock regulates metabolic processes related to the synchronization of plant traits that allows its survival and successful reproduction in pollinator dependent plants. In this work, the circadian clock genes in Nicotiana attenuata were identified and found to have a conserved function, as demonstrated by yeast two-hybrid assays and a similar hypocotyl length phenotypes on transformed Arabidopsis thaliana plants using N. attenuata transferred genes. Under long day conditions (LD) NaLHY and NaTOC1 peak at dawn and dusk, respectively, without NaZTL having marked oscillations like other plant models. The silencing of circadian genes in N. attenuata using inverted repeat (ir) technique showed similar clock transcription profile alterations of NaCAB2 and hypocotyl growth alteration as in the established clock model. Yet, irTOC1 plants had a delayed elongation and flowering under LD unlike some other model plant accessions, but it is attributable to a different habitat and genetic background, as seen in cross latitudinal studies of other species. Floral traits under circadian control are relevant to synchronize the display and scent emission of N. attenuata with its night-pollinator Manduca sexta. Flower vertical movement temporally excludes other pollinators by reduced conspicuousness. The right synchronization improves outcrossing by M. sexta in the field since dysrhythmic floral traits decreased pollination rate. However, a lack of regulation caused basically arrhythmic floral traits since irZTL had unexpected advantages during day-time outcrossing in the field due to the recruitment of day-active pollinators that provided similar reproductive results as night-pollinator dependent plants.'] | ['gnd:1048528170', 'gnd:36164-1', 'gnd:4007210-1', 'gnd:4078131-8', 'gnd:4128987-0', 'gnd:4626532-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785261591'] | ['Yon Torres, Felipe Carlos', 'Friedrich-Schiller-Universität Jena', 'Blüte', 'Tagesrhythmus', 'Gen', 'Nicotiana attenuata'] | Document
### Title: ['Timing for outcrossing : circadian clock regulates floral rhythms with large fitness consequences']
### Abstract:
['Like most organisms, plants need to keep a daily rhythm to synchronize their inner functions to the available energy and nutrients; even due to its sessile nature it’s especially important for a large group to find ways to reproduce by outcrossing. The endogenous clock regulates metabolic processes related to the synchronization of plant traits that allows its survival and successful reproduction in pollinator dependent plants. In this work, the circadian clock genes in Nicotiana attenuata were identified and found to have a conserved function, as demonstrated by yeast two-hybrid assays and a similar hypocotyl length phenotypes on transformed Arabidopsis thaliana plants using N. attenuata transferred genes. Under long day conditions (LD) NaLHY and NaTOC1 peak at dawn and dusk, respectively, without NaZTL having marked oscillations like other plant models. The silencing of circadian genes in N. attenuata using inverted repeat (ir) technique showed similar clock transcription profile alterations of NaCAB2 and hypocotyl growth alteration as in the established clock model. Yet, irTOC1 plants had a delayed elongation and flowering under LD unlike some other model plant accessions, but it is attributable to a different habitat and genetic background, as seen in cross latitudinal studies of other species. Floral traits under circadian control are relevant to synchronize the display and scent emission of N. attenuata with its night-pollinator Manduca sexta. Flower vertical movement temporally excludes other pollinators by reduced conspicuousness. The right synchronization improves outcrossing by M. sexta in the field since dysrhythmic floral traits decreased pollination rate. However, a lack of regulation caused basically arrhythmic floral traits since irZTL had unexpected advantages during day-time outcrossing in the field due to the recruitment of day-active pollinators that provided similar reproductive results as night-pollinator dependent plants.']
### GND ID:
['gnd:1048528170', 'gnd:36164-1', 'gnd:4007210-1', 'gnd:4078131-8', 'gnd:4128987-0', 'gnd:4626532-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785261591']
### GND class:
['Yon Torres, Felipe Carlos', 'Friedrich-Schiller-Universität Jena', 'Blüte', 'Tagesrhythmus', 'Gen', 'Nicotiana attenuata']
<|eot_id|> |
3A785779388.jsonld | ['The media art institution in an information-filled atmosphere : the Edith-Ruß-Haus for Media Art as a case study'] | [['This dissertation describes the processes of definition, contextualization, presentation and narration of media art in institutional space that is dedicated to it. As a case study of the Edith Russ Haus for Media Art between 2001 and 2004, this research illuminates how the media art institution shapes the perception and reception of media art. It focuses on the dynamics of the institution, which defines itself as a space and an actor between media art, art’s publics and artists: The institution is a medium in negotiations over definition of media art (chapter 1), is located in different geographic, cultural, physical and virtual topographies (chapter 2), develops programs that explore participatory aspects of contemporary (media) art and theory (chapter 3), narrates media art and its histories (chapter 4), and is conscious of itself as a permeable sphere in technoculture’s information-filled atmosphere (chapter 5). <engl.>', 'Diese Dissertation beschreibt die Prozesse von Definition, Kontextualisierung, Präsentation und dem Erzählen von Medienkunst in eigens dafür vorgesehenen Räumen. Als Fallstudie des Edith-Russ-Hauses für Medienkunst von 2001 bis 2004 untersucht die Arbeit wie die Medienkunstinstitution die Perzeption und Rezeption von Medienkunst gestaltet. Es geht um die Dynamik der Institution, die sich als Raum und Akteur zwischen Medienkunst, Publikum und KünstlerInnen definiert: Die Institution ist ein Medium für Verhandlungen über die Definitionen von Medienkunst (Kapitel 1); ist in unterschiedlichen geographischen, kulturellen, physischen und virtuellen Topografien verortet (Kapitel 2); entwickelt Programme, die partizipatorische Aspekte der zeitgenössischen (Medien)Kunst ausloten (Kapitel 3); ist Erzähler und Hersteller von Medienkunst und ihrer Geschichten (Kapitel 4) und ist bewusst Teil einer alle Sphären der heutigen Gesellschaft durchdringenden technokulturellen Atmosphäre (Kapitel 5). <dt.>']] | ['gnd:10007193-4', 'gnd:11572320X', 'gnd:140603999', 'gnd:4113418-7', 'gnd:4170787-4', 'gnd:7610872-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785779388'] | ['Edith-Ruß-Haus für Medienkunst', 'Wenk, Silke', 'Peters, Kathrin', 'Medienkunst', 'Museumskunde', 'Medientheorie'] | Document
### Title: ['The media art institution in an information-filled atmosphere : the Edith-Ruß-Haus for Media Art as a case study']
### Abstract:
[['This dissertation describes the processes of definition, contextualization, presentation and narration of media art in institutional space that is dedicated to it. As a case study of the Edith Russ Haus for Media Art between 2001 and 2004, this research illuminates how the media art institution shapes the perception and reception of media art. It focuses on the dynamics of the institution, which defines itself as a space and an actor between media art, art’s publics and artists: The institution is a medium in negotiations over definition of media art (chapter 1), is located in different geographic, cultural, physical and virtual topographies (chapter 2), develops programs that explore participatory aspects of contemporary (media) art and theory (chapter 3), narrates media art and its histories (chapter 4), and is conscious of itself as a permeable sphere in technoculture’s information-filled atmosphere (chapter 5). <engl.>', 'Diese Dissertation beschreibt die Prozesse von Definition, Kontextualisierung, Präsentation und dem Erzählen von Medienkunst in eigens dafür vorgesehenen Räumen. Als Fallstudie des Edith-Russ-Hauses für Medienkunst von 2001 bis 2004 untersucht die Arbeit wie die Medienkunstinstitution die Perzeption und Rezeption von Medienkunst gestaltet. Es geht um die Dynamik der Institution, die sich als Raum und Akteur zwischen Medienkunst, Publikum und KünstlerInnen definiert: Die Institution ist ein Medium für Verhandlungen über die Definitionen von Medienkunst (Kapitel 1); ist in unterschiedlichen geographischen, kulturellen, physischen und virtuellen Topografien verortet (Kapitel 2); entwickelt Programme, die partizipatorische Aspekte der zeitgenössischen (Medien)Kunst ausloten (Kapitel 3); ist Erzähler und Hersteller von Medienkunst und ihrer Geschichten (Kapitel 4) und ist bewusst Teil einer alle Sphären der heutigen Gesellschaft durchdringenden technokulturellen Atmosphäre (Kapitel 5). <dt.>']]
### GND ID:
['gnd:10007193-4', 'gnd:11572320X', 'gnd:140603999', 'gnd:4113418-7', 'gnd:4170787-4', 'gnd:7610872-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785779388']
### GND class:
['Edith-Ruß-Haus für Medienkunst', 'Wenk, Silke', 'Peters, Kathrin', 'Medienkunst', 'Museumskunde', 'Medientheorie']
<|eot_id|> |
3A785780572.jsonld | ['KnoVA: a Reference Architecture for Knowledge-based Visual Analytics'] | [['The considerably increasing Internet-based information processing leads to a rapidly increasing growth of the available data. Automatic analysis approaches are no longer sufficient for the analysis of this data. One approach to overcome this information overload phenomenon is visual analytics (VA). It combines the strengths of computers to process large amounts of data with human strengths such as flexibility, intuition, and contextual knowledge. In the process of VA experts apply knowledge. In many settings they apply similar knowledge continuously in several iterations across various tasks. Therefore a demand for concepts and methods to prevent needless repetitive analysis steps can be identified. This thesis presents KnoVA, a reference-architecture for knowledge-based visual analytics systems and evaluates it in two applications domains, automotive and healthcare.KnoVA consists of four parts: a model of the analysis process, a metadata model for knowledge-based visual analytics systems as well as concepts and algorithms for the extraction and the re-application of knowledge. <engl.>', 'Die seit langem deutlich zunehmende Internet-basierte Informationsverarbeitung führt zu einem rapiden Wachstum der verfügbaren Daten. Automatische Analyseverfahren sind nicht mehr ausreichend geeignet, um diese Datenbestände zu analysieren. Ein Ansatz diesem Information Overload Phänomen zu begegnen, ist die Visuelle Analyse (VA). Sie vereint Vorteile maschineller Auswertung großer Datenmengen mit menschlichen Stärken wie Flexibilität, Intuition und Hintergrundwissen. Im Prozess der VA wird Wissen durch Experten angewandt, dieallerdingsoftgleichartigesWissen in mehreren Iterationenoder über verschiedene Fragestellungen hinweg wieder verwenden. Hieraus kann ein Bedarf an Konzepten und Methoden zur Verhinderung unnötig wiederholenderSchritteabgeleitet werden. Als Ansatz hierzu wird in dieser Arbeit KnoVA, eine Referenzarchitektur für Wissensbasierte VA, vorgestellt und anhand von Beispielen aus den Domänen Automobilbau und Gesundheitswesen evaluiert.KnoVA besteht aus vier Teilen: einem Modell des Analyseprozesses,einem Meta-Datenmodell sowie Konzepten und Algorithmen zur Extraktion und Wiederanwendung von Wissen. <dt.>']] | ['gnd:1036568350', 'gnd:12181761X', 'gnd:129025437', 'gnd:4197554-6', 'gnd:4374795-4', 'gnd:4546354-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785780572'] | ['Visual Analytics', 'Appelrath, Hans-Jürgen', 'Isenberg, Tobias', 'Wissensbasiertes System', 'Informationsüberlastung', 'Wissensextraktion'] | Document
### Title: ['KnoVA: a Reference Architecture for Knowledge-based Visual Analytics']
### Abstract:
[['The considerably increasing Internet-based information processing leads to a rapidly increasing growth of the available data. Automatic analysis approaches are no longer sufficient for the analysis of this data. One approach to overcome this information overload phenomenon is visual analytics (VA). It combines the strengths of computers to process large amounts of data with human strengths such as flexibility, intuition, and contextual knowledge. In the process of VA experts apply knowledge. In many settings they apply similar knowledge continuously in several iterations across various tasks. Therefore a demand for concepts and methods to prevent needless repetitive analysis steps can be identified. This thesis presents KnoVA, a reference-architecture for knowledge-based visual analytics systems and evaluates it in two applications domains, automotive and healthcare.KnoVA consists of four parts: a model of the analysis process, a metadata model for knowledge-based visual analytics systems as well as concepts and algorithms for the extraction and the re-application of knowledge. <engl.>', 'Die seit langem deutlich zunehmende Internet-basierte Informationsverarbeitung führt zu einem rapiden Wachstum der verfügbaren Daten. Automatische Analyseverfahren sind nicht mehr ausreichend geeignet, um diese Datenbestände zu analysieren. Ein Ansatz diesem Information Overload Phänomen zu begegnen, ist die Visuelle Analyse (VA). Sie vereint Vorteile maschineller Auswertung großer Datenmengen mit menschlichen Stärken wie Flexibilität, Intuition und Hintergrundwissen. Im Prozess der VA wird Wissen durch Experten angewandt, dieallerdingsoftgleichartigesWissen in mehreren Iterationenoder über verschiedene Fragestellungen hinweg wieder verwenden. Hieraus kann ein Bedarf an Konzepten und Methoden zur Verhinderung unnötig wiederholenderSchritteabgeleitet werden. Als Ansatz hierzu wird in dieser Arbeit KnoVA, eine Referenzarchitektur für Wissensbasierte VA, vorgestellt und anhand von Beispielen aus den Domänen Automobilbau und Gesundheitswesen evaluiert.KnoVA besteht aus vier Teilen: einem Modell des Analyseprozesses,einem Meta-Datenmodell sowie Konzepten und Algorithmen zur Extraktion und Wiederanwendung von Wissen. <dt.>']]
### GND ID:
['gnd:1036568350', 'gnd:12181761X', 'gnd:129025437', 'gnd:4197554-6', 'gnd:4374795-4', 'gnd:4546354-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A785780572']
### GND class:
['Visual Analytics', 'Appelrath, Hans-Jürgen', 'Isenberg, Tobias', 'Wissensbasiertes System', 'Informationsüberlastung', 'Wissensextraktion']
<|eot_id|> |
3A786242817.jsonld | ['Trigeminale Innervation des olfaktorischen Systems : Anatomie und Funktion'] | [['The olfactory system serves for the detection of odorants and thus mainly for the identification of food sources or hazards. The trigeminal system is commonly known to have somatosensory properties. However, almost every odorant activates the olfactory as well as the trigeminal system. Many studies dealing with the perception of odorants demonstrate that there are mutual influences between the two systems, but the molecular mechanisms of these interactions are unknown. To gain a better insight into these mechanisms the trigeminal innervation of the olfactory system as well as functional aspects of the trigeminal olfactory interaction were investigated in the present work. Trigeminal fibers that contain and upon stimulation can release the peptides Substance P (SP) and calcitonin gene-related peptide (CGRP) were found in the olfactory epithelium (OE) and the olfactory bulb (OB). Within the OE in many cases these fibers are associated with cell types that differ from regular olfactory neurons. These include microvillous cells, which express components of an inositoltris-phosphate (IP3) signalling pathway and the SP receptor NK1R. Ca2+-imaging experiments show that these cells respond to SP with an increase in the intracellular Ca2+-concentration. Presumably, the response to SP is primarily carried by the release of Ca2+ from internal stores. Immunohistochemical studies indicate the expression of CGRP receptors in a subpopulation of regular olfactory neurons. In Ca2+-imaging experiments some of the cells that responded to odorants also responded to CGRP with an increase in the intracellular Ca2+-concentration. In addition, some of these cells also responded to SP indicating that they might be IP3 receptor-positive microvillous cells (see above). Preliminary results suggest that both regular olfactory neurons and microvillous IP3 receptor-positive cells can respond to CGRP. In the OB every layer is trigeminally innervated, but there is a clear preference for ventrally l', 'Das olfaktorische System dient der Wahrnehmung von Gerüchen und somit vor allem der Erkennung von Nahrungs- oder Gefahrenquellen. Dem trigeminalen System werden in erster Linie somatosensorische Eigenschaften zugeschrieben. Fast alle Gerüche aktivieren jedoch neben dem olfaktorischen auch das trigeminale System. Viele Studien, die sich mit der Wahrnehmung von Gerüchen beschäftigen, beweisen, dass es wechselseitige Einflüsse zwischen den beiden Systemen gibt. Die molekularen Mechanismen dieser Interaktionen sind jedoch unbekannt. Um ein besseres Verständnis dieser Mechanismen zu erhalten, wurden in der vorliegenden Arbeit neben der trigeminalen Innervation des Riechsystems auch funktionelle Aspekte der trigeminal/olfaktorischen Interaktion untersucht. Immunhistochemisch wurden trigeminale Fasern, die die Peptide Substanz P (SP) und calcitonin gene-related peptide (CGRP) enthalten und auf einen Reiz hin ausschütten können, im olfaktorischen Epithel (OE) und Bulbus olfactorius (OB) gefunden. Im OE stehen diese Fasern oft mit Zelltypen, die sich von regulären olfaktorischen Neuronen unterscheiden, in Verbindung. Zu diesen zählen unter anderem microvilliäre Zellen, die Komponenten eines Inositoltrisphosphat (IP3) Signalweges und den SP Rezeptor NK1R exprimieren. Die Ergebnisse von Ca2+-Imaging Experimenten an Gewebsschnitten durch das OE deuten darauf hin, dass die microvilliären Zellen auf SP sowie auf Duftstoffe mit einem Anstieg der intrazellulären Ca2+-Konzentration reagieren. Die Antwort auf SP wird vermutlich hauptsächlich durch die Freisetzung von Ca2+ aus internen Speichern getragen. Immunhistochemische Untersuchungen geben Hinweise darauf, dass CGRP Rezeptoren in einer Subpopulation von regulären olfaktorischen Neuronen exprimiert werden. In Ca2+-Imaging Versuchen antworteten einige der Zellen, die auf Duftstoffe reagierten, auch auf CGRP mit einem Anstieg der intrazellulären Ca2+-Konzentration. Manche dieser Zellen antworteten zudem auf SP, was vermuten lässt']] | ['gnd:1049669916', 'gnd:4020433-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786242817'] | ['Söchtig, Melanie Anne', 'Geruch'] | Document
### Title: ['Trigeminale Innervation des olfaktorischen Systems : Anatomie und Funktion']
### Abstract:
[['The olfactory system serves for the detection of odorants and thus mainly for the identification of food sources or hazards. The trigeminal system is commonly known to have somatosensory properties. However, almost every odorant activates the olfactory as well as the trigeminal system. Many studies dealing with the perception of odorants demonstrate that there are mutual influences between the two systems, but the molecular mechanisms of these interactions are unknown. To gain a better insight into these mechanisms the trigeminal innervation of the olfactory system as well as functional aspects of the trigeminal olfactory interaction were investigated in the present work. Trigeminal fibers that contain and upon stimulation can release the peptides Substance P (SP) and calcitonin gene-related peptide (CGRP) were found in the olfactory epithelium (OE) and the olfactory bulb (OB). Within the OE in many cases these fibers are associated with cell types that differ from regular olfactory neurons. These include microvillous cells, which express components of an inositoltris-phosphate (IP3) signalling pathway and the SP receptor NK1R. Ca2+-imaging experiments show that these cells respond to SP with an increase in the intracellular Ca2+-concentration. Presumably, the response to SP is primarily carried by the release of Ca2+ from internal stores. Immunohistochemical studies indicate the expression of CGRP receptors in a subpopulation of regular olfactory neurons. In Ca2+-imaging experiments some of the cells that responded to odorants also responded to CGRP with an increase in the intracellular Ca2+-concentration. In addition, some of these cells also responded to SP indicating that they might be IP3 receptor-positive microvillous cells (see above). Preliminary results suggest that both regular olfactory neurons and microvillous IP3 receptor-positive cells can respond to CGRP. In the OB every layer is trigeminally innervated, but there is a clear preference for ventrally l', 'Das olfaktorische System dient der Wahrnehmung von Gerüchen und somit vor allem der Erkennung von Nahrungs- oder Gefahrenquellen. Dem trigeminalen System werden in erster Linie somatosensorische Eigenschaften zugeschrieben. Fast alle Gerüche aktivieren jedoch neben dem olfaktorischen auch das trigeminale System. Viele Studien, die sich mit der Wahrnehmung von Gerüchen beschäftigen, beweisen, dass es wechselseitige Einflüsse zwischen den beiden Systemen gibt. Die molekularen Mechanismen dieser Interaktionen sind jedoch unbekannt. Um ein besseres Verständnis dieser Mechanismen zu erhalten, wurden in der vorliegenden Arbeit neben der trigeminalen Innervation des Riechsystems auch funktionelle Aspekte der trigeminal/olfaktorischen Interaktion untersucht. Immunhistochemisch wurden trigeminale Fasern, die die Peptide Substanz P (SP) und calcitonin gene-related peptide (CGRP) enthalten und auf einen Reiz hin ausschütten können, im olfaktorischen Epithel (OE) und Bulbus olfactorius (OB) gefunden. Im OE stehen diese Fasern oft mit Zelltypen, die sich von regulären olfaktorischen Neuronen unterscheiden, in Verbindung. Zu diesen zählen unter anderem microvilliäre Zellen, die Komponenten eines Inositoltrisphosphat (IP3) Signalweges und den SP Rezeptor NK1R exprimieren. Die Ergebnisse von Ca2+-Imaging Experimenten an Gewebsschnitten durch das OE deuten darauf hin, dass die microvilliären Zellen auf SP sowie auf Duftstoffe mit einem Anstieg der intrazellulären Ca2+-Konzentration reagieren. Die Antwort auf SP wird vermutlich hauptsächlich durch die Freisetzung von Ca2+ aus internen Speichern getragen. Immunhistochemische Untersuchungen geben Hinweise darauf, dass CGRP Rezeptoren in einer Subpopulation von regulären olfaktorischen Neuronen exprimiert werden. In Ca2+-Imaging Versuchen antworteten einige der Zellen, die auf Duftstoffe reagierten, auch auf CGRP mit einem Anstieg der intrazellulären Ca2+-Konzentration. Manche dieser Zellen antworteten zudem auf SP, was vermuten lässt']]
### GND ID:
['gnd:1049669916', 'gnd:4020433-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786242817']
### GND class:
['Söchtig, Melanie Anne', 'Geruch']
<|eot_id|> |
3A786360763.jsonld | ['Synthese eines Ansamycin Hybrids : Studien zur Identifikation der ungewöhnlichen Azidreduktaseaktivität in A. pretosium'] | ['Totalsynthese, Mutasynthese, Ansamitocin, Geldanamycin, enzymatische Azidreduktion. - Total synthesis, mutasynthesis, enzymatic azide reduction'] | ['gnd:1058639099', 'gnd:4142584-4', 'gnd:4348499-2', 'gnd:4412308-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786360763'] | ['Jürjens, Gerrit', 'Ansamycine', 'Reductasen', 'Totalsynthese'] | Document
### Title: ['Synthese eines Ansamycin Hybrids : Studien zur Identifikation der ungewöhnlichen Azidreduktaseaktivität in A. pretosium']
### Abstract:
['Totalsynthese, Mutasynthese, Ansamitocin, Geldanamycin, enzymatische Azidreduktion. - Total synthesis, mutasynthesis, enzymatic azide reduction']
### GND ID:
['gnd:1058639099', 'gnd:4142584-4', 'gnd:4348499-2', 'gnd:4412308-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786360763']
### GND class:
['Jürjens, Gerrit', 'Ansamycine', 'Reductasen', 'Totalsynthese']
<|eot_id|> |
3A786439467.jsonld | ['Zur Langzeitsimulation der morphodynamischen Entwicklung tidebeeinflusster Marschgewässer'] | [['Tidal marsh-watercourses form a significant link between marine and fluvial environment. As consequence bi-directional forces due to asymmetrie tides and inland runoff influence morphodynamic processes with presence of cohesive sediments in these marsh-watercourses. The combination of the high inter-tidal area proportion and anthropogenie impacts results in special requirements for the longterm approach. Identified significant processes in marsh-watercourses were integrated into a long-term approach, taking detailed field measurements into account. Applying this numerical long-term approach the range of uncertainty for varying natural and anthropogenie impacts and a shift of morphodynamic processes with are analyzed.', 'Tidebeeinflusste Marschgewässer stellen ein bedeutendes Bindeglied zwischen Küsten- und Binnengewässern dar. Infolgedessen prägen Einwirkungen wie asymmetrische Tiden und der Binnenabfluss unter Anwesenheit von kohäsiven Sedimenten die morphodynamischen Prozesse in diesen Marschgewässern. Im Zusammenspiel mit dem hohen intertidalen Flächenanteil dieser Gewässer und anthropogenen Eingriffen ergeben sich besondere Anforderungen an das Langzeitverfahren. Die maßgeblichen Prozesse in Marschgewässern wurden u.a. mit Hilfe von Naturmessungen miteingebunden und ein zugehöriges Langzeitverfahren entwickelt. Durch die Anwendung dieses Verfahrens wurden Streubreiten für natürliche Randbedingungen und anthropogene Eingriffe sowie langfristige Veränderungen in der Gewässermorphologie untersucht und ausgewiesen']] | ['gnd:1054649316', 'gnd:4000631-1', 'gnd:4020945-3', 'gnd:4033287-1', 'gnd:4034036-3', 'gnd:4055072-2', 'gnd:4074598-3', 'gnd:4131972-2', 'gnd:4132461-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786439467'] | ['Donner, Monika', 'Ästuar', 'Gezeiten', 'Krückau', 'Längsschnittuntersuchung', 'Simulation', 'Marschland', 'Fluss', 'Dynamische Geomorphologie'] | Document
### Title: ['Zur Langzeitsimulation der morphodynamischen Entwicklung tidebeeinflusster Marschgewässer']
### Abstract:
[['Tidal marsh-watercourses form a significant link between marine and fluvial environment. As consequence bi-directional forces due to asymmetrie tides and inland runoff influence morphodynamic processes with presence of cohesive sediments in these marsh-watercourses. The combination of the high inter-tidal area proportion and anthropogenie impacts results in special requirements for the longterm approach. Identified significant processes in marsh-watercourses were integrated into a long-term approach, taking detailed field measurements into account. Applying this numerical long-term approach the range of uncertainty for varying natural and anthropogenie impacts and a shift of morphodynamic processes with are analyzed.', 'Tidebeeinflusste Marschgewässer stellen ein bedeutendes Bindeglied zwischen Küsten- und Binnengewässern dar. Infolgedessen prägen Einwirkungen wie asymmetrische Tiden und der Binnenabfluss unter Anwesenheit von kohäsiven Sedimenten die morphodynamischen Prozesse in diesen Marschgewässern. Im Zusammenspiel mit dem hohen intertidalen Flächenanteil dieser Gewässer und anthropogenen Eingriffen ergeben sich besondere Anforderungen an das Langzeitverfahren. Die maßgeblichen Prozesse in Marschgewässern wurden u.a. mit Hilfe von Naturmessungen miteingebunden und ein zugehöriges Langzeitverfahren entwickelt. Durch die Anwendung dieses Verfahrens wurden Streubreiten für natürliche Randbedingungen und anthropogene Eingriffe sowie langfristige Veränderungen in der Gewässermorphologie untersucht und ausgewiesen']]
### GND ID:
['gnd:1054649316', 'gnd:4000631-1', 'gnd:4020945-3', 'gnd:4033287-1', 'gnd:4034036-3', 'gnd:4055072-2', 'gnd:4074598-3', 'gnd:4131972-2', 'gnd:4132461-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786439467']
### GND class:
['Donner, Monika', 'Ästuar', 'Gezeiten', 'Krückau', 'Längsschnittuntersuchung', 'Simulation', 'Marschland', 'Fluss', 'Dynamische Geomorphologie']
<|eot_id|> |
3A786796375.jsonld | ['Laser link acquisition for the GRACE follow-on laser ranging interferometer'] | ['GRACE follow-on, laser link acquisition, mode expansion method. - Laser Link Akquisition, Modenzerlegung'] | ['gnd:1053737033', 'gnd:4136498-3', 'gnd:4159732-1', 'gnd:4166807-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786796375'] | ['Mahrdt, Christoph', 'Satellit', 'Heterodynspektroskopie', 'Laserinterferometrie'] | Document
### Title: ['Laser link acquisition for the GRACE follow-on laser ranging interferometer']
### Abstract:
['GRACE follow-on, laser link acquisition, mode expansion method. - Laser Link Akquisition, Modenzerlegung']
### GND ID:
['gnd:1053737033', 'gnd:4136498-3', 'gnd:4159732-1', 'gnd:4166807-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786796375']
### GND class:
['Mahrdt, Christoph', 'Satellit', 'Heterodynspektroskopie', 'Laserinterferometrie']
<|eot_id|> |
3A786808217.jsonld | ['The geochemical response of sedimentary archives to rapid recent glacier retreat at the western Antarctic Peninsula (WAP) : from source to sink : von der Quelle zur Senke'] | [['Off King George Island (western Antarctic Peninsula) major and trace elements were studied in porewaters and sedimentary archives. The results of provenance analyses conducted on marine sediments from Maxwell Bay suggest regional climate variability during the Late Holocene. Moreover, concurrent with the rapid glacier retreat sediment accumulation rates have more than tripled since the middle of the 20th century. Using guano-associated bio-elements in lake sediments the waxing and waning of local penguin colonies on Ardley Island could be reconstructed. Changes in local penguin populations during the Holocene are linked to changes in climate, sea ice extent, relative sea level and volcanic eruptions. Porewater data (nutrients, sulphate, Fe, Mn, U, Mo, Re) were used to determine major pathways of organic matter degradation in coastal sediments. Mathematical models let assume that Antarctic shelf areas form a more important source for bioavailable Fe in the Southern Ocean than previously thought. <engl.>', 'Vor King George Island (Westantarktische Halbinsel) wurden Haupt- und Spurenelemente in Porenwässern und sedimentären Archiven untersucht. Die Ergebnisse von Provenanzanalysen mariner Sedimente der Maxwell Bay weisen auf regionale Klimaveränderungen im Spätholozän hin. Zudem hat sich die Sedimentakkumulationsrate seit Mitte des 20. Jahrhunderts bedingt durch den rapiden Gletscherrückzug mehr als verdreifacht. Mit Hilfe guano-assozierter Bioelemente in Seesedimenten konnte das Auftreten lokaler Pinguinkolonien auf Ardley Island rekonstruiert werden. Holozäne Populationsschwankungen wurden auf Änderungen des Klimas, der Meereisbedeckung, des relativen Meeresspiegels und auf vulkanische Eruptionen zurückgeführt. Porenwasserdaten (Nährstoffe, Sulfat, Fe, Mn, U, Mo, Re) wurden verwendet, um Hauptabbauwege von organischem Material in Küstensedimenten zu bestimmen. Mathematische Modelle lassen vermuten, dass antarktische Schelfgebiete eine größere Quelle bioverfügbarem Eisens für den Südozean darstellen, als bisher angenommen. <dt.>']] | ['gnd:1045597163', 'gnd:1056028483', 'gnd:4020198-3', 'gnd:4054079-0', 'gnd:4079206-7', 'gnd:4164199-1', 'gnd:4288836-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786808217'] | ['Rullkötter, Jürgen', 'Monien, Patrick', 'Geochemie', 'Sediment', 'Westantarktis', 'Klimaänderung', 'Porenwasser'] | Document
### Title: ['The geochemical response of sedimentary archives to rapid recent glacier retreat at the western Antarctic Peninsula (WAP) : from source to sink : von der Quelle zur Senke']
### Abstract:
[['Off King George Island (western Antarctic Peninsula) major and trace elements were studied in porewaters and sedimentary archives. The results of provenance analyses conducted on marine sediments from Maxwell Bay suggest regional climate variability during the Late Holocene. Moreover, concurrent with the rapid glacier retreat sediment accumulation rates have more than tripled since the middle of the 20th century. Using guano-associated bio-elements in lake sediments the waxing and waning of local penguin colonies on Ardley Island could be reconstructed. Changes in local penguin populations during the Holocene are linked to changes in climate, sea ice extent, relative sea level and volcanic eruptions. Porewater data (nutrients, sulphate, Fe, Mn, U, Mo, Re) were used to determine major pathways of organic matter degradation in coastal sediments. Mathematical models let assume that Antarctic shelf areas form a more important source for bioavailable Fe in the Southern Ocean than previously thought. <engl.>', 'Vor King George Island (Westantarktische Halbinsel) wurden Haupt- und Spurenelemente in Porenwässern und sedimentären Archiven untersucht. Die Ergebnisse von Provenanzanalysen mariner Sedimente der Maxwell Bay weisen auf regionale Klimaveränderungen im Spätholozän hin. Zudem hat sich die Sedimentakkumulationsrate seit Mitte des 20. Jahrhunderts bedingt durch den rapiden Gletscherrückzug mehr als verdreifacht. Mit Hilfe guano-assozierter Bioelemente in Seesedimenten konnte das Auftreten lokaler Pinguinkolonien auf Ardley Island rekonstruiert werden. Holozäne Populationsschwankungen wurden auf Änderungen des Klimas, der Meereisbedeckung, des relativen Meeresspiegels und auf vulkanische Eruptionen zurückgeführt. Porenwasserdaten (Nährstoffe, Sulfat, Fe, Mn, U, Mo, Re) wurden verwendet, um Hauptabbauwege von organischem Material in Küstensedimenten zu bestimmen. Mathematische Modelle lassen vermuten, dass antarktische Schelfgebiete eine größere Quelle bioverfügbarem Eisens für den Südozean darstellen, als bisher angenommen. <dt.>']]
### GND ID:
['gnd:1045597163', 'gnd:1056028483', 'gnd:4020198-3', 'gnd:4054079-0', 'gnd:4079206-7', 'gnd:4164199-1', 'gnd:4288836-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786808217']
### GND class:
['Rullkötter, Jürgen', 'Monien, Patrick', 'Geochemie', 'Sediment', 'Westantarktis', 'Klimaänderung', 'Porenwasser']
<|eot_id|> |
3A78694305X.jsonld | ['Moralische Motivation im Kindes- und Jugendalter : Entwicklung, Einflussfaktoren und Verhalten'] | ['Moralische Motivation, moralische Identität, moralische Entwicklung. - Moral motivation, moral identity, moral development'] | ['gnd:1058766511', 'gnd:4015602-3', 'gnd:4028859-6', 'gnd:4030550-8', 'gnd:4040364-6', 'gnd:4055179-9', 'gnd:4189699-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78694305X'] | ['Doering, Bettina', 'Ethik', 'Jugend', 'Kind', 'Motivation', 'Sittliche Erziehung', 'Werterziehung'] | Document
### Title: ['Moralische Motivation im Kindes- und Jugendalter : Entwicklung, Einflussfaktoren und Verhalten']
### Abstract:
['Moralische Motivation, moralische Identität, moralische Entwicklung. - Moral motivation, moral identity, moral development']
### GND ID:
['gnd:1058766511', 'gnd:4015602-3', 'gnd:4028859-6', 'gnd:4030550-8', 'gnd:4040364-6', 'gnd:4055179-9', 'gnd:4189699-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A78694305X']
### GND class:
['Doering, Bettina', 'Ethik', 'Jugend', 'Kind', 'Motivation', 'Sittliche Erziehung', 'Werterziehung']
<|eot_id|> |
3A786954485.jsonld | ['Sedimentology and composition of the Takrouna Formation, northern Victoria Land, Antarctic : provenance and depositional evolution of a Permian Gondwana basin'] | ['During the late Paleozoic a series of sedimentary basins occupied the eastern margin of Gondwana that is considered as long-lasting subduction-related plate boundary. Nature, evolution and provenance of some of these basins, for example of the Permian Victoria Basin in the Ross Sea sector of East Antarctica, are still poorly understood. The up to 300 m thick succession of siliciclastic sedimentary rocks of the Permian Takrouna Formation in northern Victoria Land represents the fossil record of the northern part of this basin system, exposed within an outcrop belt with an extension of 125 × 160 km. This study presents a detailed description of the spatial and temporal evolution of the Permian Takrouna Formation. The reconstruction of the source areas and the depositional evolution of the continental Victoria Basin contribute to a broader understanding of the tectonic regime at the eastern margin of Gondwana during the Permian. Based on the investigations of vertical and lateral sections in six mountain ranges the development of sedimentary architecture and facies was reconstructed. The combination of sedimentological, petrographic and geochemical methods has been used to determine the controls on deposition and provenance. Petrographic and geochemical tools include the study of heavy and light mineral assemblages, the cathodoluminescence of detrital quartz, the whole-rock geochemical composition of sandstones and mudstones, the composition of selected minerals, as well as U-Pb age dating of detrital zircons. Further a petrographic and geochemical characterization of the abundant organic material has also been used to investigate the depositional environment and also the thermal history of the succession. The integration of this data set and comparison to the data gained from selected samples of the Permian Weller Coal Measures in southern Victoria Land enable a paleogeographic reconstruction of the Victoria Basin and the drainage system that occupied the study area.'] | ['gnd:1052297765', 'gnd:36164-1', 'gnd:4108241-2', 'gnd:4121648-9', 'gnd:4155003-1', 'gnd:4173820-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786954485'] | ['John, Nadine', 'Friedrich-Schiller-Universität Jena', 'Victorialand', 'Sedimentologie', 'Formation (Geologie)', 'Perm (Geologie)'] | Document
### Title: ['Sedimentology and composition of the Takrouna Formation, northern Victoria Land, Antarctic : provenance and depositional evolution of a Permian Gondwana basin']
### Abstract:
['During the late Paleozoic a series of sedimentary basins occupied the eastern margin of Gondwana that is considered as long-lasting subduction-related plate boundary. Nature, evolution and provenance of some of these basins, for example of the Permian Victoria Basin in the Ross Sea sector of East Antarctica, are still poorly understood. The up to 300 m thick succession of siliciclastic sedimentary rocks of the Permian Takrouna Formation in northern Victoria Land represents the fossil record of the northern part of this basin system, exposed within an outcrop belt with an extension of 125 × 160 km. This study presents a detailed description of the spatial and temporal evolution of the Permian Takrouna Formation. The reconstruction of the source areas and the depositional evolution of the continental Victoria Basin contribute to a broader understanding of the tectonic regime at the eastern margin of Gondwana during the Permian. Based on the investigations of vertical and lateral sections in six mountain ranges the development of sedimentary architecture and facies was reconstructed. The combination of sedimentological, petrographic and geochemical methods has been used to determine the controls on deposition and provenance. Petrographic and geochemical tools include the study of heavy and light mineral assemblages, the cathodoluminescence of detrital quartz, the whole-rock geochemical composition of sandstones and mudstones, the composition of selected minerals, as well as U-Pb age dating of detrital zircons. Further a petrographic and geochemical characterization of the abundant organic material has also been used to investigate the depositional environment and also the thermal history of the succession. The integration of this data set and comparison to the data gained from selected samples of the Permian Weller Coal Measures in southern Victoria Land enable a paleogeographic reconstruction of the Victoria Basin and the drainage system that occupied the study area.']
### GND ID:
['gnd:1052297765', 'gnd:36164-1', 'gnd:4108241-2', 'gnd:4121648-9', 'gnd:4155003-1', 'gnd:4173820-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A786954485']
### GND class:
['John, Nadine', 'Friedrich-Schiller-Universität Jena', 'Victorialand', 'Sedimentologie', 'Formation (Geologie)', 'Perm (Geologie)']
<|eot_id|> |
3A787218189.jsonld | ['Novel methods for the analysis of small molecule fragmentation mass spectra'] | ['The identification of small molecules, such as metabolites, in a high throughput manner plays an important in many research areas. Mass spectrometry (MS) is one of the predominant analysis technologies and is much more sensitive than nuclear magnetic resonance spectroscopy. Fragmentation of the molecules is used to obtain information beyond its mass. Gas chromatography-MS is one of the oldest and most widespread techniques for the analysis of small molecules. Commonly, the molecule is fragmented using electron ionization (EI). Using this technique, the molecular ion peak is often barely visible in the mass spectrum or even absent. We present a method to calculate fragmentation trees from high mass accuracy EI spectra, which annotate the peaks in the mass spectrum with molecular formulas of fragments and explain relevant fragmentation pathways. Fragmentation trees enable the identification of the molecular ion and its molecular formula if the molecular ion is present in the spectrum. The method works even if the molecular ion is of very low abundance. MS experts confirm that the calculated trees correspond very well to known fragmentation mechanisms.Using pairwise local alignments of fragmentation trees, structural and chemical similarities to already-known molecules can be determined. In order to compare a fragmentation tree of an unknown metabolite to a huge database of fragmentation trees, fast algorithms for solving the tree alignment problem are required. Unfortunately the alignment of unordered trees, such as fragmentation trees, is NP-hard. We present three exact algorithms for the problem. Evaluation of our methods showed that thousands of alignments can be computed in a matter of minutes. Both the computation and the comparison of fragmentation trees are rule-free approaches that require no chemical knowledge about the unknown molecule and thus will be very helpful in the automated analysis of metabolites that are not included in common libraries.'] | ['gnd:1052085121', 'gnd:36164-1', 'gnd:4037882-2', 'gnd:4138579-2', 'gnd:4155138-2', 'gnd:4596131-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787218189'] | ['Hufsky, Franziska', 'Friedrich-Schiller-Universität Jena', 'Massenspektrometrie', 'Metabolit', 'Fragmentierung', 'High throughput screening'] | Document
### Title: ['Novel methods for the analysis of small molecule fragmentation mass spectra']
### Abstract:
['The identification of small molecules, such as metabolites, in a high throughput manner plays an important in many research areas. Mass spectrometry (MS) is one of the predominant analysis technologies and is much more sensitive than nuclear magnetic resonance spectroscopy. Fragmentation of the molecules is used to obtain information beyond its mass. Gas chromatography-MS is one of the oldest and most widespread techniques for the analysis of small molecules. Commonly, the molecule is fragmented using electron ionization (EI). Using this technique, the molecular ion peak is often barely visible in the mass spectrum or even absent. We present a method to calculate fragmentation trees from high mass accuracy EI spectra, which annotate the peaks in the mass spectrum with molecular formulas of fragments and explain relevant fragmentation pathways. Fragmentation trees enable the identification of the molecular ion and its molecular formula if the molecular ion is present in the spectrum. The method works even if the molecular ion is of very low abundance. MS experts confirm that the calculated trees correspond very well to known fragmentation mechanisms.Using pairwise local alignments of fragmentation trees, structural and chemical similarities to already-known molecules can be determined. In order to compare a fragmentation tree of an unknown metabolite to a huge database of fragmentation trees, fast algorithms for solving the tree alignment problem are required. Unfortunately the alignment of unordered trees, such as fragmentation trees, is NP-hard. We present three exact algorithms for the problem. Evaluation of our methods showed that thousands of alignments can be computed in a matter of minutes. Both the computation and the comparison of fragmentation trees are rule-free approaches that require no chemical knowledge about the unknown molecule and thus will be very helpful in the automated analysis of metabolites that are not included in common libraries.']
### GND ID:
['gnd:1052085121', 'gnd:36164-1', 'gnd:4037882-2', 'gnd:4138579-2', 'gnd:4155138-2', 'gnd:4596131-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787218189']
### GND class:
['Hufsky, Franziska', 'Friedrich-Schiller-Universität Jena', 'Massenspektrometrie', 'Metabolit', 'Fragmentierung', 'High throughput screening']
<|eot_id|> |
3A787330795.jsonld | ['Analyse und Synthese von zyklischen Herstellungsprozessen artifizieller Diversity Covering (DiCo) Malariavakzinkandidaten'] | ['Malaria-Impfstoffkandidaten, Pichia pastoris, sequentielle Produktion, design of experiments, Expressionsmodellierung und Prozesssimulation. - Malaria vaccine candidates, sequential production, expression modeling and process simulation'] | ['gnd:1058616099', 'gnd:4026655-2', 'gnd:4037197-9', 'gnd:4307166-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787330795'] | ['Martens, Sanja', 'Impfstoff', 'Malaria', 'Bioverfahrenstechnik'] | Document
### Title: ['Analyse und Synthese von zyklischen Herstellungsprozessen artifizieller Diversity Covering (DiCo) Malariavakzinkandidaten']
### Abstract:
['Malaria-Impfstoffkandidaten, Pichia pastoris, sequentielle Produktion, design of experiments, Expressionsmodellierung und Prozesssimulation. - Malaria vaccine candidates, sequential production, expression modeling and process simulation']
### GND ID:
['gnd:1058616099', 'gnd:4026655-2', 'gnd:4037197-9', 'gnd:4307166-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787330795']
### GND class:
['Martens, Sanja', 'Impfstoff', 'Malaria', 'Bioverfahrenstechnik']
<|eot_id|> |
3A787337064.jsonld | ['Direct laser bonding of transparent materials using ultrashort laser pulses at high repetition rates'] | ['Transparent materials surround us everywhere in our daily life. Especially glass has a dominant role due to its excellent optical, mechanical and chemical properties. For the processing of glass numerous techniques are well known, some of them are more than several hundred years old. In contrast, the reliable and stable bonding of two different glasses is still a demanding problem. Most of the developed glass bonding techniques are adapted from well known silicon waver techniques [1, 2]. All the established methods e.g. optical contacting, direct bonding or anodic bonding exhibit certain disadvantages as these methods were not designed for the bonding of glasses [3, 4]. For example, optical contacting - were two ultraclean glass samples are pressed together and adhere due to the van der Waals forces between their surface atoms - yields only weak bonds. Alternatively, laser pulses can be used to weld the glass samples together. Commonly high average power cw-lasers are used for laser welding. However for the absorption of cwlaser radiation an opaque material is required. Alternatively, ultrashort laser pulses have proven to be a powerful tool for the processing of transparent materials within the last two decades. The extremely short pulse duration allow nonlinear processes that fundamentally differ from traditional light-matter interaction mechanisms. Nonlinear absorption induced by ultrashort pulses leads to an extremely non-equilibrium state in a confined volume resulting in a variety of different material modifications [5, 6]. Due to the highly localized energy deposition machining of sub micron features and full three dimensional processing of transparent materials become feasible [5, 7]. In fused silica three different types of modifications can be induced: isotropic and anisotropic index changes [5, 6, 8, 9, 10] and the generation of small cavities [11, 12]. Promising applications include the realization of photonic circuits [13, 14, 15, 16], birefringent elements [17, 18], microfluidic channels [19] or data storage devices [20].'] | ['gnd:1167001796', 'gnd:36164-1', 'gnd:4021142-3', 'gnd:4222149-3', 'gnd:4232594-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787337064'] | ['Richter, Sören', 'Friedrich-Schiller-Universität Jena', 'Glas', 'Ultrakurzer Lichtimpuls', 'Bonden'] | Document
### Title: ['Direct laser bonding of transparent materials using ultrashort laser pulses at high repetition rates']
### Abstract:
['Transparent materials surround us everywhere in our daily life. Especially glass has a dominant role due to its excellent optical, mechanical and chemical properties. For the processing of glass numerous techniques are well known, some of them are more than several hundred years old. In contrast, the reliable and stable bonding of two different glasses is still a demanding problem. Most of the developed glass bonding techniques are adapted from well known silicon waver techniques [1, 2]. All the established methods e.g. optical contacting, direct bonding or anodic bonding exhibit certain disadvantages as these methods were not designed for the bonding of glasses [3, 4]. For example, optical contacting - were two ultraclean glass samples are pressed together and adhere due to the van der Waals forces between their surface atoms - yields only weak bonds. Alternatively, laser pulses can be used to weld the glass samples together. Commonly high average power cw-lasers are used for laser welding. However for the absorption of cwlaser radiation an opaque material is required. Alternatively, ultrashort laser pulses have proven to be a powerful tool for the processing of transparent materials within the last two decades. The extremely short pulse duration allow nonlinear processes that fundamentally differ from traditional light-matter interaction mechanisms. Nonlinear absorption induced by ultrashort pulses leads to an extremely non-equilibrium state in a confined volume resulting in a variety of different material modifications [5, 6]. Due to the highly localized energy deposition machining of sub micron features and full three dimensional processing of transparent materials become feasible [5, 7]. In fused silica three different types of modifications can be induced: isotropic and anisotropic index changes [5, 6, 8, 9, 10] and the generation of small cavities [11, 12]. Promising applications include the realization of photonic circuits [13, 14, 15, 16], birefringent elements [17, 18], microfluidic channels [19] or data storage devices [20].']
### GND ID:
['gnd:1167001796', 'gnd:36164-1', 'gnd:4021142-3', 'gnd:4222149-3', 'gnd:4232594-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787337064']
### GND class:
['Richter, Sören', 'Friedrich-Schiller-Universität Jena', 'Glas', 'Ultrakurzer Lichtimpuls', 'Bonden']
<|eot_id|> |
3A787519111.jsonld | ['Funktionelle und strukturelle Charakterisierung von Varianten des respiratorischen Komplex I'] | [['Zusammenfassung: Reactive oxygen species (ROS) are suspected to be involved in the development of neurodegenerative diseases such as Parkinson\'s disease and Alzheimer\'s disease. In addition, ROS is ascribed an important role in the aging process. The NADH:ubiquinone oxidoreductase, also called respiratory complex I, is the most important source of ROS in the mitochondrion. The enzyme complex couples the electron transfer from NADH to ubiquinone with the translocation of protons across the membrane. Because of its simpler structure of the bacterial complex I is considered as a model system for the eukaryotic complex. The Escherichia coli complex I consists of 13 subunits, which are named NuoA to NuoN. The enzyme carries nine iron-sulfur (Fe/S) clusters and one flavin mononucleotide (FMN) as cofactors. In this work, specific questions concerning the mechanism of complex I were clarified by characterization of site-directed mutants. Effects of mutations on the enzymatic activity were tested using the E. coli complex I. The structural changes of the mutations were, if possible, characterized by a soluble subcomplex consisting of subunits NuoE and F of the Aquifex aeolicus complex I. By mutagenesis of Glu183(NuoF) and characterization of variants, this amino acid has been identified as a key position for the substrate discrimination of NADH and NADPH by complex I. The increased ROS production of the variants during NADH consumption could be explained by the structure of the A. aeolicus NuoEF variant E185D(NuoF) with bound NAD+. The mutation Tyr204Cys(NuoF) was detected in a patient suffering from Leigh-like syndrome. The cause of this disease has been studied by mutagenesis of E. coli complex I. The characterized variants showed up to 80% reduction in catalytic efficiency and 13-fold increase in ROS production. In a cooperation project with the group of Dr. Judy Hirst (MRC , Cambridge ), the midpoint potential of the Fe/S cluster N1a was lowered up to 100 mV by site-directed mutagenesis. N1a of the produced E. coli complex I variant could not be reduced by NADH. This led to an increased H2O2 production by 60 % and shows the functional significance of this cluster as a protection against increased ROS production. The structures of NuoEF with bound substrate and product show a conformational change of the peptide bond of Glu95(NuoF). This reorientation seems to be a kind of "product ejection mechanism". By mutagenesis this peptide bond was fixed in the conformati ...', 'Zusammenfassung: Reaktive Sauerstoffspezies (reactive oxygen species; ROS) stehen im Verdacht an der Entstehung neurodegenerativer Erkrankungen, wie Morbus Parkinson und Morbus Alzheimer beteiligt zu sein. Zusätzlich wird ROS eine wesentliche Rolle beim Alterungsprozess zugeschrieben. Die NADH:Ubichinon Oxidoreduktase, auch respiratorischer Komplex I genannt, gilt als die bedeutendste Quelle von ROS im Mitochondrium. Der Enzymkomplex koppelt den Elektronentransfer von NADH auf Ubichinon mit der Translokation von Protonen über die Membran. Aufgrund seines einfacheren Aufbaus wird der bakterielle Komplex I als Modellsystem für den eukaryotischen Komplex angesehen. Der Escherichia coli Komplex I besteht aus 13 Untereinheiten, die mit NuoA bis NuoN bezeichnet werden und trägt neun Eisen-Schwefel (Fe/S)-Zentren sowie ein Flavinmononukleotid (FMN) als Kofaktoren. In dieser Arbeit wurden spezifische Fragen zum Mechanismus des Komplex I durch Charakterisierung ortsgerichteter Mutanten geklärt. Auswirkungen der Mutationen auf die enzymatische Aktivität wurden mit dem E. coli Komplex I untersucht. Die strukturellen Änderungen der Mutationen wurden, falls möglich, mit dem löslichen Subkomplex aus den Untereinheiten NuoE und F des Aquifex aeolicus Komplex I charakterisiert. Durch Mutagenese des Glu183(NuoF) und durch Charakterisierung der Varianten konnte diese Position als Schlüsselposition für die Substratunterscheidung von NADH und NADPH durch Komplex I identifiziert werden. Die erhöhte ROS-Produktion der Varianten bei der Umsetzung von NADH konnte durch die Struktur der A. aeolicus Variante E185D(NuoF) mit gebundenem Produkt erklärt werden. Die Mutation Tyr204Cys(NuoF) wurde bei einem am Leigh-like-Syndrom erkrankten Patienten nachgewiesen. Die Ursache dieser Erkrankung wurde mit durch die Mutagenese des E. coli Komplex I untersucht. Die charakterisierten Varianten zeigten eine, bis zu 80% verringerte katalytische Effizienz und 13-fach erhöhte ROS-Produktion. In einem Kooperations-Projekt mit der Gruppe von Dr. Judy Hirst (MRC, Cambridge) wurde das Mittenpunktspotential des Fe/S-Zentrums N1a durch ortsgerichtete Mutagenese um bis zu 100 mV abgesenkt. Das Zentrum konnte in der dargestellten Variante nicht mit NADH reduziert werden, was eine um 60% erhöhte H2O2-Produktion zur Folge hatte und funktionelle Bedeutung dieses Zentrums als Schutz vor einer erhöhten ROS-Produktion zeigt. Die Strukturen des NuoEF mit gebundenem Produkt un ...']] | ['gnd:1052360386', 'gnd:4236432-2', 'gnd:4316153-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787519111'] | ['Frick, Klaudia', 'Reaktive Sauerstoffspezies', 'NADH-Dehydrogenase (Ubichinon)'] | Document
### Title: ['Funktionelle und strukturelle Charakterisierung von Varianten des respiratorischen Komplex I']
### Abstract:
[['Zusammenfassung: Reactive oxygen species (ROS) are suspected to be involved in the development of neurodegenerative diseases such as Parkinson\'s disease and Alzheimer\'s disease. In addition, ROS is ascribed an important role in the aging process. The NADH:ubiquinone oxidoreductase, also called respiratory complex I, is the most important source of ROS in the mitochondrion. The enzyme complex couples the electron transfer from NADH to ubiquinone with the translocation of protons across the membrane. Because of its simpler structure of the bacterial complex I is considered as a model system for the eukaryotic complex. The Escherichia coli complex I consists of 13 subunits, which are named NuoA to NuoN. The enzyme carries nine iron-sulfur (Fe/S) clusters and one flavin mononucleotide (FMN) as cofactors. In this work, specific questions concerning the mechanism of complex I were clarified by characterization of site-directed mutants. Effects of mutations on the enzymatic activity were tested using the E. coli complex I. The structural changes of the mutations were, if possible, characterized by a soluble subcomplex consisting of subunits NuoE and F of the Aquifex aeolicus complex I. By mutagenesis of Glu183(NuoF) and characterization of variants, this amino acid has been identified as a key position for the substrate discrimination of NADH and NADPH by complex I. The increased ROS production of the variants during NADH consumption could be explained by the structure of the A. aeolicus NuoEF variant E185D(NuoF) with bound NAD+. The mutation Tyr204Cys(NuoF) was detected in a patient suffering from Leigh-like syndrome. The cause of this disease has been studied by mutagenesis of E. coli complex I. The characterized variants showed up to 80% reduction in catalytic efficiency and 13-fold increase in ROS production. In a cooperation project with the group of Dr. Judy Hirst (MRC , Cambridge ), the midpoint potential of the Fe/S cluster N1a was lowered up to 100 mV by site-directed mutagenesis. N1a of the produced E. coli complex I variant could not be reduced by NADH. This led to an increased H2O2 production by 60 % and shows the functional significance of this cluster as a protection against increased ROS production. The structures of NuoEF with bound substrate and product show a conformational change of the peptide bond of Glu95(NuoF). This reorientation seems to be a kind of "product ejection mechanism". By mutagenesis this peptide bond was fixed in the conformati ...', 'Zusammenfassung: Reaktive Sauerstoffspezies (reactive oxygen species; ROS) stehen im Verdacht an der Entstehung neurodegenerativer Erkrankungen, wie Morbus Parkinson und Morbus Alzheimer beteiligt zu sein. Zusätzlich wird ROS eine wesentliche Rolle beim Alterungsprozess zugeschrieben. Die NADH:Ubichinon Oxidoreduktase, auch respiratorischer Komplex I genannt, gilt als die bedeutendste Quelle von ROS im Mitochondrium. Der Enzymkomplex koppelt den Elektronentransfer von NADH auf Ubichinon mit der Translokation von Protonen über die Membran. Aufgrund seines einfacheren Aufbaus wird der bakterielle Komplex I als Modellsystem für den eukaryotischen Komplex angesehen. Der Escherichia coli Komplex I besteht aus 13 Untereinheiten, die mit NuoA bis NuoN bezeichnet werden und trägt neun Eisen-Schwefel (Fe/S)-Zentren sowie ein Flavinmononukleotid (FMN) als Kofaktoren. In dieser Arbeit wurden spezifische Fragen zum Mechanismus des Komplex I durch Charakterisierung ortsgerichteter Mutanten geklärt. Auswirkungen der Mutationen auf die enzymatische Aktivität wurden mit dem E. coli Komplex I untersucht. Die strukturellen Änderungen der Mutationen wurden, falls möglich, mit dem löslichen Subkomplex aus den Untereinheiten NuoE und F des Aquifex aeolicus Komplex I charakterisiert. Durch Mutagenese des Glu183(NuoF) und durch Charakterisierung der Varianten konnte diese Position als Schlüsselposition für die Substratunterscheidung von NADH und NADPH durch Komplex I identifiziert werden. Die erhöhte ROS-Produktion der Varianten bei der Umsetzung von NADH konnte durch die Struktur der A. aeolicus Variante E185D(NuoF) mit gebundenem Produkt erklärt werden. Die Mutation Tyr204Cys(NuoF) wurde bei einem am Leigh-like-Syndrom erkrankten Patienten nachgewiesen. Die Ursache dieser Erkrankung wurde mit durch die Mutagenese des E. coli Komplex I untersucht. Die charakterisierten Varianten zeigten eine, bis zu 80% verringerte katalytische Effizienz und 13-fach erhöhte ROS-Produktion. In einem Kooperations-Projekt mit der Gruppe von Dr. Judy Hirst (MRC, Cambridge) wurde das Mittenpunktspotential des Fe/S-Zentrums N1a durch ortsgerichtete Mutagenese um bis zu 100 mV abgesenkt. Das Zentrum konnte in der dargestellten Variante nicht mit NADH reduziert werden, was eine um 60% erhöhte H2O2-Produktion zur Folge hatte und funktionelle Bedeutung dieses Zentrums als Schutz vor einer erhöhten ROS-Produktion zeigt. Die Strukturen des NuoEF mit gebundenem Produkt un ...']]
### GND ID:
['gnd:1052360386', 'gnd:4236432-2', 'gnd:4316153-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787519111']
### GND class:
['Frick, Klaudia', 'Reaktive Sauerstoffspezies', 'NADH-Dehydrogenase (Ubichinon)']
<|eot_id|> |
3A787717371.jsonld | ['Gottes Werk und Teufels Wirken : Traum, Vision, Imagination in der frühbyzantinischen monastischen Literatur'] | [['The volume provides the first comprehensive presentation of imaginary phenomena such as dreams and visions in early Byzantine monastic literature. Drawing on a broad range of sources, it examines imaginary experiences according to their literary expression and the cultural historical background they reflect, thus offering profound insights into the diverse treatment of imaginary phenomena in monastic literature.', 'Die erste umfassende Darstellung von imaginären Phänomenen wie Träumen und Visionen innerhalb der frühbyzantinischen monastischen Literatur. Auf einer breiten Quellengrundlage werden imaginäre Erfahrungen nach ihrer literarischen Verarbeitung und den sich darin widerspiegelnden kulturgeschichtlichen Hintergründen untersucht. Das Werk bietet einen tiefgreifenden Einblick in die vielseitige Verarbeitung der Thematik in der monastischen Literatur.', 'Main description: Die erste umfassende Darstellung von imaginären Phänomenen wie Träumen und Visionen innerhalb der frühbyzantinischen monastischen Literatur. Auf einer breiten Quellengrundlage werden imaginäre Erfahrungen nach ihrer literarischen Verarbeitung und den sich darin widerspiegelnden kulturgeschichtlichen Hintergründen untersucht. Das Werk bietet einen tiefgreifenden Einblick in die vielseitige Verarbeitung der Thematik in der monastischen Literatur.']] | ['gnd:1044381833', 'gnd:4009256-2', 'gnd:4060747-1', 'gnd:4063618-5', 'gnd:4072730-0', 'gnd:4074927-7', 'gnd:4132327-0', 'gnd:4786953-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787717371'] | ['Krönung, Bettina', 'Byzantinisches Reich', 'Traum', 'Vision', 'Imagination', 'Mönchtum', 'Geistliche Literatur', 'Spirituelle Erfahrung'] | Document
### Title: ['Gottes Werk und Teufels Wirken : Traum, Vision, Imagination in der frühbyzantinischen monastischen Literatur']
### Abstract:
[['The volume provides the first comprehensive presentation of imaginary phenomena such as dreams and visions in early Byzantine monastic literature. Drawing on a broad range of sources, it examines imaginary experiences according to their literary expression and the cultural historical background they reflect, thus offering profound insights into the diverse treatment of imaginary phenomena in monastic literature.', 'Die erste umfassende Darstellung von imaginären Phänomenen wie Träumen und Visionen innerhalb der frühbyzantinischen monastischen Literatur. Auf einer breiten Quellengrundlage werden imaginäre Erfahrungen nach ihrer literarischen Verarbeitung und den sich darin widerspiegelnden kulturgeschichtlichen Hintergründen untersucht. Das Werk bietet einen tiefgreifenden Einblick in die vielseitige Verarbeitung der Thematik in der monastischen Literatur.', 'Main description: Die erste umfassende Darstellung von imaginären Phänomenen wie Träumen und Visionen innerhalb der frühbyzantinischen monastischen Literatur. Auf einer breiten Quellengrundlage werden imaginäre Erfahrungen nach ihrer literarischen Verarbeitung und den sich darin widerspiegelnden kulturgeschichtlichen Hintergründen untersucht. Das Werk bietet einen tiefgreifenden Einblick in die vielseitige Verarbeitung der Thematik in der monastischen Literatur.']]
### GND ID:
['gnd:1044381833', 'gnd:4009256-2', 'gnd:4060747-1', 'gnd:4063618-5', 'gnd:4072730-0', 'gnd:4074927-7', 'gnd:4132327-0', 'gnd:4786953-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787717371']
### GND class:
['Krönung, Bettina', 'Byzantinisches Reich', 'Traum', 'Vision', 'Imagination', 'Mönchtum', 'Geistliche Literatur', 'Spirituelle Erfahrung']
<|eot_id|> |
3A787896128.jsonld | ['Sprache des Krieges : Deutungen des Ersten Weltkriegs in zionistischer Publizistik und Literatur (1914-1918)'] | ['"In Zionist journalism and literature during the First World War, the poetic language of Zionism was transformed into a language of war. Eva Edelmann-Ohler shows that Zionist interpretations of the war refer back to templates that existed before the war and were applied in different discursive arenas. Literary resonances of these interpretative patterns can be seen in the works of Franz Kafka, Arnold Zweig, and Felix Theilhaber"--'] | ['gnd:105982924X', 'gnd:4049716-1', 'gnd:4067864-7', 'gnd:4079163-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787896128'] | ['Edelmann-Ohler, Eva', 'Rezeption', 'Zionismus', 'Erster Weltkrieg'] | Document
### Title: ['Sprache des Krieges : Deutungen des Ersten Weltkriegs in zionistischer Publizistik und Literatur (1914-1918)']
### Abstract:
['"In Zionist journalism and literature during the First World War, the poetic language of Zionism was transformed into a language of war. Eva Edelmann-Ohler shows that Zionist interpretations of the war refer back to templates that existed before the war and were applied in different discursive arenas. Literary resonances of these interpretative patterns can be seen in the works of Franz Kafka, Arnold Zweig, and Felix Theilhaber"--']
### GND ID:
['gnd:105982924X', 'gnd:4049716-1', 'gnd:4067864-7', 'gnd:4079163-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787896128']
### GND class:
['Edelmann-Ohler, Eva', 'Rezeption', 'Zionismus', 'Erster Weltkrieg']
<|eot_id|> |
3A787896306.jsonld | ['Studierte Dichter : zum Spannungsverhältnis von Dichtung und philologisch-historischen Wissenschaften im 19. Jahrhundert'] | ['"As the modern philological sciences were just emerging, poets were well educated-most of them had studied philology, and thus understood its claims to knowledge and its methods. The fertile and intensive interaction between literature and science that took place in this era is the subject of this book. It explores the interface between literary history and the history of the modern philological sciences." --'] | ['gnd:123465907', 'gnd:4011882-4', 'gnd:4036034-9', 'gnd:4053309-8', 'gnd:4167882-5', 'gnd:4199236-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787896306'] | ['Dehrmann, Mark-Georg', 'Deutschland', 'Literaturwissenschaft', 'Schriftsteller', 'Literaturproduktion', 'Philologe'] | Document
### Title: ['Studierte Dichter : zum Spannungsverhältnis von Dichtung und philologisch-historischen Wissenschaften im 19. Jahrhundert']
### Abstract:
['"As the modern philological sciences were just emerging, poets were well educated-most of them had studied philology, and thus understood its claims to knowledge and its methods. The fertile and intensive interaction between literature and science that took place in this era is the subject of this book. It explores the interface between literary history and the history of the modern philological sciences." --']
### GND ID:
['gnd:123465907', 'gnd:4011882-4', 'gnd:4036034-9', 'gnd:4053309-8', 'gnd:4167882-5', 'gnd:4199236-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787896306']
### GND class:
['Dehrmann, Mark-Georg', 'Deutschland', 'Literaturwissenschaft', 'Schriftsteller', 'Literaturproduktion', 'Philologe']
<|eot_id|> |
3A787963100.jsonld | ['Enzymatic synthesis of functional polyesters and their modification by grafting reactions'] | [['Novel amphiphilic graft copolymers having biodegradable aliphatic polyesters as polymer backbone have been successfully synthesized. Enzymatic polymerization technique was utilized to prepare first the polyester backbone with free pendant functional groups in one step. The resulting pendant groups were then utilized either to initiate the polymerization of the side chains or to connect the side chains by “grafting onto” strategy. The physical properties of the resulting graft copolymers were characterized in bulk, in water and at air/water interface by utilization a wide array of characterization techniques. All graft copolymers are able to form either micelles or nanoparticles with hydrodynamics radius smaller than 100 Å. Interestingly, PGA17-g-(PCL24-b-PEO44) can form polymersomes of an average diameter of 25 nm. These polymersomes form stable worm-like aggregates caused by collision as a result of shear forces during the preparation.', 'Neuartige amphiphile Pfropfcopolymere mit biologisch abbaubaren aliphatischen Polyestern in der Polymerhauptkette wurden erfolgreich synthetisiert. Durch enzymatische Polymerisation wurde in einem Schritt zunächst ein Polyester-Grundgerüst hergestellt, das an den Seitenketten freie funktionelle Gruppen trägt. Diese funktionellen Gruppen wurden anschließend verwendet, um entweder eine Polymerisation der Seitenketten zu initiieren oder um die Seitenketten mittels "grafting onto"-Strategie zu verbinden. Die physikalischen Eigenschaften der erhaltenen Pfropfcopolymere wurden sowohl in reiner Form, als auch in wässriger Lösung, sowie an der Luft-Wasser-Grenzfläche mit zahlreichen analytischen Verfahren charakterisiert. Die untersuchten Pfropfcopolymere können alle entweder Mizellen oder Nanopartikel ausbilden, deren hydrodynamische Radien kleiner als 100 Å sind. Interessanterweise können sich aus PGA17-g-(PCL24-b-PEO44) Polymersome mit einem durchschnittlichen Durchmesser von 25 nm bilden. Durch Scherkräfte, die während des Herstellungsprozesses bei Kollisionen auftreten, bilden diese Polymersome stabile wurmartige Aggregate.', 'enzymatic polymerization; amphiphilic graft copolymers; “Click chemistry”; biodegradable polymers; nanoparticles; polymersomes; Langmuir trough; Langmuir–Blodgett films', 'enzymatische Polymerisation; amphiphile Blockcopolymere; "Click-Chemie"; bioabbaubare Polymere; Nanopartikel; Polymersome; Langmuir-Trog; Langmuir-Blodgett-Filme']] | ['gnd:4174104-3', 'gnd:4333369-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787963100'] | ['Pfropfcopolymere', 'Nanopartikel'] | Document
### Title: ['Enzymatic synthesis of functional polyesters and their modification by grafting reactions']
### Abstract:
[['Novel amphiphilic graft copolymers having biodegradable aliphatic polyesters as polymer backbone have been successfully synthesized. Enzymatic polymerization technique was utilized to prepare first the polyester backbone with free pendant functional groups in one step. The resulting pendant groups were then utilized either to initiate the polymerization of the side chains or to connect the side chains by “grafting onto” strategy. The physical properties of the resulting graft copolymers were characterized in bulk, in water and at air/water interface by utilization a wide array of characterization techniques. All graft copolymers are able to form either micelles or nanoparticles with hydrodynamics radius smaller than 100 Å. Interestingly, PGA17-g-(PCL24-b-PEO44) can form polymersomes of an average diameter of 25 nm. These polymersomes form stable worm-like aggregates caused by collision as a result of shear forces during the preparation.', 'Neuartige amphiphile Pfropfcopolymere mit biologisch abbaubaren aliphatischen Polyestern in der Polymerhauptkette wurden erfolgreich synthetisiert. Durch enzymatische Polymerisation wurde in einem Schritt zunächst ein Polyester-Grundgerüst hergestellt, das an den Seitenketten freie funktionelle Gruppen trägt. Diese funktionellen Gruppen wurden anschließend verwendet, um entweder eine Polymerisation der Seitenketten zu initiieren oder um die Seitenketten mittels "grafting onto"-Strategie zu verbinden. Die physikalischen Eigenschaften der erhaltenen Pfropfcopolymere wurden sowohl in reiner Form, als auch in wässriger Lösung, sowie an der Luft-Wasser-Grenzfläche mit zahlreichen analytischen Verfahren charakterisiert. Die untersuchten Pfropfcopolymere können alle entweder Mizellen oder Nanopartikel ausbilden, deren hydrodynamische Radien kleiner als 100 Å sind. Interessanterweise können sich aus PGA17-g-(PCL24-b-PEO44) Polymersome mit einem durchschnittlichen Durchmesser von 25 nm bilden. Durch Scherkräfte, die während des Herstellungsprozesses bei Kollisionen auftreten, bilden diese Polymersome stabile wurmartige Aggregate.', 'enzymatic polymerization; amphiphilic graft copolymers; “Click chemistry”; biodegradable polymers; nanoparticles; polymersomes; Langmuir trough; Langmuir–Blodgett films', 'enzymatische Polymerisation; amphiphile Blockcopolymere; "Click-Chemie"; bioabbaubare Polymere; Nanopartikel; Polymersome; Langmuir-Trog; Langmuir-Blodgett-Filme']]
### GND ID:
['gnd:4174104-3', 'gnd:4333369-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A787963100']
### GND class:
['Pfropfcopolymere', 'Nanopartikel']
<|eot_id|> |
3A788243527.jsonld | ['Intra- and interspecific variation of functional traits, growth performance and belowground competition in [Populus] species'] | ['Short-rotation forestry (SRF) systems provide sustaining resource supply that is needed to meet the rapidly increasing demand in wood products and renewable energy. Poplar species (Populus spp.) are frequently used for such plantations as they maintain high yield along wide environmental ranges. Specifically aspen (Populus tremula and P. tremuloides) reach considerable productivity even on poor soils and exhibit relatively high drought tolerance when compared to other taxa of the genus. However, the use of aspen in SRF systems is not well established. The aim of this st...'] | ['gnd:4173223-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788243527'] | ['Pappel'] | Document
### Title: ['Intra- and interspecific variation of functional traits, growth performance and belowground competition in [Populus] species']
### Abstract:
['Short-rotation forestry (SRF) systems provide sustaining resource supply that is needed to meet the rapidly increasing demand in wood products and renewable energy. Poplar species (Populus spp.) are frequently used for such plantations as they maintain high yield along wide environmental ranges. Specifically aspen (Populus tremula and P. tremuloides) reach considerable productivity even on poor soils and exhibit relatively high drought tolerance when compared to other taxa of the genus. However, the use of aspen in SRF systems is not well established. The aim of this st...']
### GND ID:
['gnd:4173223-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788243527']
### GND class:
['Pappel']
<|eot_id|> |
3A788332554.jsonld | ['The distribution of attention in RSVP tasks and its sensitivity to affect, personality traits and estradiol'] | [['In this thesis, the influences of positive and negative affect state, the personality trait neuroticism, and the hormone estradiol on selective attention are explored in three studies. In Study 1 a double-stream RSVP paradigm was used to explore if attention can be spatially diffused and focused by affect. A spatial interpretation of the diffuse mental state was not found. Study 2 studied the distribution of attention as influenced by neuroticism and cognitive control. Results confirmed that as expected low control lowered relative power difference between the ssVEP responses to the two streams. In Study 3, the effect of fluctuating estradiol over the menstrual cycle on attention was investigated with alpha asymmetry as a possible mediator. Results indicate relationships between alpha and estradiol, and between alpha and performance. <engl.>', 'Diese Arbeit untersucht den Einfluss von positivem und negativem Affekt, des Persönlichkeitsmerkmals Neurotizismus, und des Hormons Estradiol auf selektive Aufmerksamkeit. In Studie 1 wurde der Affekt in einem double-stream RSVP Paradigma manipuliert, um zu untersuchen ob dadurch Aufmerksamkeit räumlich erweitert oder fokussiert wird. Es konnte kein solcher Effekt nachgewiesen werden. Studie 2 untersuchte den Zusammenhang von Neurotizismus und kognitiver Kontrolle auf die Aufmerksamkeitsverteilung mittels eines ssVEP Paradigmas. Die Ergebnisse zeigen einen negativen Zusammenhang zwischen Neurotizismus und Power-Unterschieden zwischen zwei ssVEP Strömen. In Studie 3 wurde der Einfluss der menstruellen Estradiolschwankung, mit Alpha-Asymmetrie als möglichen Mediator, auf die Aufmerksamkeit erforscht. Die Ergebnisse zeigten Zusammenhänge zwischen Alpha und Estradiol, sowie zwischen Alpha und behavioraler Leistung. <dt.>']] | ['gnd:1055850228', 'gnd:12963462X', 'gnd:4019702-5', 'gnd:4064317-7', 'gnd:4068943-8', 'gnd:4135470-9', 'gnd:4165216-2', 'gnd:4171600-0', 'gnd:4172466-5', 'gnd:4297929-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788332554'] | ['Dhinakaran, Janani', 'Kranczioch, Cornelia', 'Gefühl', 'Wahrnehmung', 'Aufmerksamkeit', 'Affekt', 'Konzentrationsfähigkeit', 'Neurotizismus', 'Estradiol', 'Achtsamkeit'] | Document
### Title: ['The distribution of attention in RSVP tasks and its sensitivity to affect, personality traits and estradiol']
### Abstract:
[['In this thesis, the influences of positive and negative affect state, the personality trait neuroticism, and the hormone estradiol on selective attention are explored in three studies. In Study 1 a double-stream RSVP paradigm was used to explore if attention can be spatially diffused and focused by affect. A spatial interpretation of the diffuse mental state was not found. Study 2 studied the distribution of attention as influenced by neuroticism and cognitive control. Results confirmed that as expected low control lowered relative power difference between the ssVEP responses to the two streams. In Study 3, the effect of fluctuating estradiol over the menstrual cycle on attention was investigated with alpha asymmetry as a possible mediator. Results indicate relationships between alpha and estradiol, and between alpha and performance. <engl.>', 'Diese Arbeit untersucht den Einfluss von positivem und negativem Affekt, des Persönlichkeitsmerkmals Neurotizismus, und des Hormons Estradiol auf selektive Aufmerksamkeit. In Studie 1 wurde der Affekt in einem double-stream RSVP Paradigma manipuliert, um zu untersuchen ob dadurch Aufmerksamkeit räumlich erweitert oder fokussiert wird. Es konnte kein solcher Effekt nachgewiesen werden. Studie 2 untersuchte den Zusammenhang von Neurotizismus und kognitiver Kontrolle auf die Aufmerksamkeitsverteilung mittels eines ssVEP Paradigmas. Die Ergebnisse zeigen einen negativen Zusammenhang zwischen Neurotizismus und Power-Unterschieden zwischen zwei ssVEP Strömen. In Studie 3 wurde der Einfluss der menstruellen Estradiolschwankung, mit Alpha-Asymmetrie als möglichen Mediator, auf die Aufmerksamkeit erforscht. Die Ergebnisse zeigten Zusammenhänge zwischen Alpha und Estradiol, sowie zwischen Alpha und behavioraler Leistung. <dt.>']]
### GND ID:
['gnd:1055850228', 'gnd:12963462X', 'gnd:4019702-5', 'gnd:4064317-7', 'gnd:4068943-8', 'gnd:4135470-9', 'gnd:4165216-2', 'gnd:4171600-0', 'gnd:4172466-5', 'gnd:4297929-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788332554']
### GND class:
['Dhinakaran, Janani', 'Kranczioch, Cornelia', 'Gefühl', 'Wahrnehmung', 'Aufmerksamkeit', 'Affekt', 'Konzentrationsfähigkeit', 'Neurotizismus', 'Estradiol', 'Achtsamkeit']
<|eot_id|> |
3A788332562.jsonld | ['Unmasking fault tolerance : quantifying deterministic recovery dynamics in probabilistic environments'] | [['The present thesis focuses on distributed systems operating under probabilistic influences like faults. How well can such systems provide their service under the effects of faults? How well can they recover from faults? The present thesis introduces with limiting window availability a suitable measure to answer such questions, and presents a method for its computation. For the computation, the transition models of the systems are constructed, which are exponential in the size of the constituting system models. This is known as state space explosion. Combining decomposition and lumping - methods for state space reduction from the domain of model checking - allows to dampen the state space explosion. <engl.>', 'Die vorliegende Arbeit betrachtet verteilte Systeme, welche unter wahrscheinlichkeitstheoretischen Einflüssen, beispielsweise Fehlern, operieren. Wie gut können solche Systeme unter den Auswirkungen von Fehlern ihren Dienst erbringen? Wie gut können sie sich von Fehlern erholen? Die vorliegende Arbeit stellt mit der limiting window availability ein geeignetes Maß zur Beantwortung dieser Fragen vor und präsentiert eine Methode, um es zu berechnen. Zur Berechnung werden die Transitionsmodelle der Systeme konstruiert, welche exponentiell in der Größe der zugrundeliegenden Systemmodelle sind. Dies ist auch bekannt als Zustandsraumexplosion. Die Kombination von Dekomposition und Lumping - Methoden zur Zustandsraumreduktion aus dem Bereich Modellprüfung - erlaubt es, die Zustandsraumexplosion zu dämpfen. <dt.>']] | ['gnd:4037612-6', 'gnd:4123192-2', 'gnd:4149030-7', 'gnd:4434799-6', 'gnd:7761791-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788332562'] | ['Markov-Kette', 'Fehlertoleranz', 'Dekomposition', 'Model Checking', 'Selbststabilisierung'] | Document
### Title: ['Unmasking fault tolerance : quantifying deterministic recovery dynamics in probabilistic environments']
### Abstract:
[['The present thesis focuses on distributed systems operating under probabilistic influences like faults. How well can such systems provide their service under the effects of faults? How well can they recover from faults? The present thesis introduces with limiting window availability a suitable measure to answer such questions, and presents a method for its computation. For the computation, the transition models of the systems are constructed, which are exponential in the size of the constituting system models. This is known as state space explosion. Combining decomposition and lumping - methods for state space reduction from the domain of model checking - allows to dampen the state space explosion. <engl.>', 'Die vorliegende Arbeit betrachtet verteilte Systeme, welche unter wahrscheinlichkeitstheoretischen Einflüssen, beispielsweise Fehlern, operieren. Wie gut können solche Systeme unter den Auswirkungen von Fehlern ihren Dienst erbringen? Wie gut können sie sich von Fehlern erholen? Die vorliegende Arbeit stellt mit der limiting window availability ein geeignetes Maß zur Beantwortung dieser Fragen vor und präsentiert eine Methode, um es zu berechnen. Zur Berechnung werden die Transitionsmodelle der Systeme konstruiert, welche exponentiell in der Größe der zugrundeliegenden Systemmodelle sind. Dies ist auch bekannt als Zustandsraumexplosion. Die Kombination von Dekomposition und Lumping - Methoden zur Zustandsraumreduktion aus dem Bereich Modellprüfung - erlaubt es, die Zustandsraumexplosion zu dämpfen. <dt.>']]
### GND ID:
['gnd:4037612-6', 'gnd:4123192-2', 'gnd:4149030-7', 'gnd:4434799-6', 'gnd:7761791-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788332562']
### GND class:
['Markov-Kette', 'Fehlertoleranz', 'Dekomposition', 'Model Checking', 'Selbststabilisierung']
<|eot_id|> |
3A788497804.jsonld | ['Steuerung lokaler Reaktionszonen mit Ultramikroelektroden'] | [['To improve the resolution of the local microelectrochemical surface structuring of soft organic layers, temporary reaction zones were produced in liquid media. By picking up the concept of chemical lens or confined etchant layer technique, the limiting of the reaction zones of micro-electro-chemically produced bromine and locally changing of the proton concentration succeeded through the use of scavenger molecules (L-cystine, cystamine, acetate-phosphate buffer). These molecules consume the locally generated etchant in the solution volume by fast homogeneous reaction. By confocal laser scanning microscopy, reaction zones of microelectrochemically generated bromine and pH changes in the solution were visually observed and quantified. There was also an investigation of the effects of buffers on the shift of the pH value in the vicinity of microelectrodes. The lateral resolution of the micro-structuring of self-assembled monolayers has been improved through the use of scavenger molecules and characterized by scanning electrochemical microscopy. <engl.>', 'Zur Verbesserung der Auflösung der lokalen mikroelektrochemischen Oberflächenstrukturierung weicher organischer Schichten wurden temporäre Reaktionszonen in flüssigen Medien erzeugt. Durch das Aufgreifen des Konzepts der chemischen Linse bzw. der confined etchant layer technique gelang die Limitierung von Reaktionszonen von mikroelektrochemisch erzeugtem Brom und lokal veränderten Protonenkonzentrationen durch den Einsatz von Fängermolekülen (L-Cystin, Cystamin, Acetat-Phosphatpuffer). Diese Moleküle verbrauchen durch schnelle homogene Reaktion das lokal erzeugte Ätzmittel in der Lösung. Durch die Konfokalmikroskopie wurden Reaktionszonen von mikroelektrochemisch erzeugtem Brom und pH-Veränderungen in der Lösung optisch beobachtet und quantifiziert. Auch erfolgte die Untersuchung der Auswirkungen von Puffern auf die Verschiebung des pH-Wertes in der Nähe von Mikroelektroden. Die laterale Auflösung der Mikrostrukturierung von selbstorganisierten Monoschichten wurde durch den Einsatz von Fängermolekülen verbessert und durch die elektrochemische Rastermikroskopie charakterisiert. <dt.>']] | ['gnd:1126046434', 'gnd:123133033', 'gnd:4151764-7', 'gnd:4192623-7', 'gnd:4330328-6', 'gnd:4336446-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788497804'] | ['Beckhaus, Rüdiger', 'Wittstock, Gunther', 'Elektrochemische Reaktion', 'Mikroelektrode', 'Rastersondenmikroskopie', 'Konfokale Mikroskopie'] | Document
### Title: ['Steuerung lokaler Reaktionszonen mit Ultramikroelektroden']
### Abstract:
[['To improve the resolution of the local microelectrochemical surface structuring of soft organic layers, temporary reaction zones were produced in liquid media. By picking up the concept of chemical lens or confined etchant layer technique, the limiting of the reaction zones of micro-electro-chemically produced bromine and locally changing of the proton concentration succeeded through the use of scavenger molecules (L-cystine, cystamine, acetate-phosphate buffer). These molecules consume the locally generated etchant in the solution volume by fast homogeneous reaction. By confocal laser scanning microscopy, reaction zones of microelectrochemically generated bromine and pH changes in the solution were visually observed and quantified. There was also an investigation of the effects of buffers on the shift of the pH value in the vicinity of microelectrodes. The lateral resolution of the micro-structuring of self-assembled monolayers has been improved through the use of scavenger molecules and characterized by scanning electrochemical microscopy. <engl.>', 'Zur Verbesserung der Auflösung der lokalen mikroelektrochemischen Oberflächenstrukturierung weicher organischer Schichten wurden temporäre Reaktionszonen in flüssigen Medien erzeugt. Durch das Aufgreifen des Konzepts der chemischen Linse bzw. der confined etchant layer technique gelang die Limitierung von Reaktionszonen von mikroelektrochemisch erzeugtem Brom und lokal veränderten Protonenkonzentrationen durch den Einsatz von Fängermolekülen (L-Cystin, Cystamin, Acetat-Phosphatpuffer). Diese Moleküle verbrauchen durch schnelle homogene Reaktion das lokal erzeugte Ätzmittel in der Lösung. Durch die Konfokalmikroskopie wurden Reaktionszonen von mikroelektrochemisch erzeugtem Brom und pH-Veränderungen in der Lösung optisch beobachtet und quantifiziert. Auch erfolgte die Untersuchung der Auswirkungen von Puffern auf die Verschiebung des pH-Wertes in der Nähe von Mikroelektroden. Die laterale Auflösung der Mikrostrukturierung von selbstorganisierten Monoschichten wurde durch den Einsatz von Fängermolekülen verbessert und durch die elektrochemische Rastermikroskopie charakterisiert. <dt.>']]
### GND ID:
['gnd:1126046434', 'gnd:123133033', 'gnd:4151764-7', 'gnd:4192623-7', 'gnd:4330328-6', 'gnd:4336446-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A788497804']
### GND class:
['Beckhaus, Rüdiger', 'Wittstock, Gunther', 'Elektrochemische Reaktion', 'Mikroelektrode', 'Rastersondenmikroskopie', 'Konfokale Mikroskopie']
<|eot_id|> |
3A789400243.jsonld | ["Information flows in the context of EU policy-making : affiliation networks and the post-2012 reform of the EU's Common Fisheries Policy"] | ['Information flows in EU policy-making are heavily dependent on personal networks, both within the Brussels sphere but also reaching outside the narrow limits of the Belgian capital. These networks develop for example in the course of formal and informal meetings or at the sidelines of such meetings. A plethora of committees at European, transnational and regional level provides the basis for the establishment of pan-European networks. By studying affiliation to those committees, basic network structures can be uncovered. These affiliation network structures can then be used to predict EU information flows, assuming that certain positions within the network are advantageous for tapping into streams of information while others are too remote and peripheral to provide access to information early enough. This study has tested those assumptions for the case of the reform of the Common Fisheries Policy for the time after 2012. Through the analysis of an affiliation network based on participation in 10 different fisheries policy committees over two years (2009 and 2010), network data for an EU-wide network of about 1300 fisheries interest group representatives and more than 200 events was collected. The structure of this network showed a number of interesting patterns, such as not surprisingly a rather central role of Brussels-based committees but also close relations of very specific interests to the Brussels-cluster and stronger relations between geographically closer maritime regions. The analysis of information flows then focused on access to draft EU Commission documents containing the upcoming proposal for a new basic regulation of the Common Fisheries Policy. It was first documented that it would have been impossible to officially obtain this document and that personal networks were thus the most likely sources for fisheries policy actors to obtain access to these “leaks” in early 2011. A survey of a sample of 65 actors from the initial network supported these findings: Only a very small group had accessed the draft directly from the Commission. Most respondents who obtained access to the draft had received it from other actors, highlighting the networked flow of informal information in EU politics. Furthermore, the testing of the hypotheses connecting network positions and the level of informedness indicated that presence in or connections to the Brussels sphere had both advantages for overall access to the draft document and with regard to timing. Methodologically, challenges of both the network analysis and the analysis of information flows but also their relevance for the study of EU politics have been documented. In summary, this study has laid the foundation for a different way to study EU policy-making by connecting topical and methodological elements – such as affiliation network analysis and EU committee governance – which so far have not been considered together, thereby contributing in various ways to political science and EU studies.'] | ['gnd:4017316-1', 'gnd:4369958-3', 'gnd:5098525-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789400243'] | ['Fischereirecht', 'Politisches Netzwerk', 'Europäische Union'] | Document
### Title: ["Information flows in the context of EU policy-making : affiliation networks and the post-2012 reform of the EU's Common Fisheries Policy"]
### Abstract:
['Information flows in EU policy-making are heavily dependent on personal networks, both within the Brussels sphere but also reaching outside the narrow limits of the Belgian capital. These networks develop for example in the course of formal and informal meetings or at the sidelines of such meetings. A plethora of committees at European, transnational and regional level provides the basis for the establishment of pan-European networks. By studying affiliation to those committees, basic network structures can be uncovered. These affiliation network structures can then be used to predict EU information flows, assuming that certain positions within the network are advantageous for tapping into streams of information while others are too remote and peripheral to provide access to information early enough. This study has tested those assumptions for the case of the reform of the Common Fisheries Policy for the time after 2012. Through the analysis of an affiliation network based on participation in 10 different fisheries policy committees over two years (2009 and 2010), network data for an EU-wide network of about 1300 fisheries interest group representatives and more than 200 events was collected. The structure of this network showed a number of interesting patterns, such as not surprisingly a rather central role of Brussels-based committees but also close relations of very specific interests to the Brussels-cluster and stronger relations between geographically closer maritime regions. The analysis of information flows then focused on access to draft EU Commission documents containing the upcoming proposal for a new basic regulation of the Common Fisheries Policy. It was first documented that it would have been impossible to officially obtain this document and that personal networks were thus the most likely sources for fisheries policy actors to obtain access to these “leaks” in early 2011. A survey of a sample of 65 actors from the initial network supported these findings: Only a very small group had accessed the draft directly from the Commission. Most respondents who obtained access to the draft had received it from other actors, highlighting the networked flow of informal information in EU politics. Furthermore, the testing of the hypotheses connecting network positions and the level of informedness indicated that presence in or connections to the Brussels sphere had both advantages for overall access to the draft document and with regard to timing. Methodologically, challenges of both the network analysis and the analysis of information flows but also their relevance for the study of EU politics have been documented. In summary, this study has laid the foundation for a different way to study EU policy-making by connecting topical and methodological elements – such as affiliation network analysis and EU committee governance – which so far have not been considered together, thereby contributing in various ways to political science and EU studies.']
### GND ID:
['gnd:4017316-1', 'gnd:4369958-3', 'gnd:5098525-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789400243']
### GND class:
['Fischereirecht', 'Politisches Netzwerk', 'Europäische Union']
<|eot_id|> |
3A789506246.jsonld | ['Drosophila olfactory neuroecology : function and evolution'] | ['Olfaction is the single most studied means of insect chemoreception. Many insects are sensitive to olfactory signals that advertise relevant ecological information concerning nutrient resources, competitors, predators, potential mates, and host suitability (Price et al., 2011). The olfactory system of the vinegar fly, Drosophila melanogaster, serves as a genetically and anatomically simple model for studying how sensory input is translated into behavioral output, because only two synapses isolate the input peripheral detection of ecologically relevant olfactory signals from the output behavioral navigation. This genetic and anatomical simplicity of the Drosophila olfactory system allowed us to further our understanding of the Drosophila olfactory neuroecology. Here, we have shown that the vinegar fly, Drosophila melanogaster, has two olfactory pathways, one that underlies the hardwired innate avoidance of harmful microbes and a second pathway for oviposition in Citrus substrates. We also showed that the peripheral odor detection machinery of D. erecta and D. mojavensis have been modified to match the olfactory needs of their respective ecological systems and associated host plants. Thus the findings of this thesis, while most directly pertinent to the advancement of our understanding of the basic science behind olfactory mechanisms, may also be useful in integrated pest management strategies for these and other potential pest insects'] | ['gnd:1058617524', 'gnd:1171368399', 'gnd:1192684982', 'gnd:120793342', 'gnd:36164-1', 'gnd:4071050-6', 'gnd:4078168-9', 'gnd:4150708-3', 'gnd:4156903-9', 'gnd:4184779-9', 'gnd:4209106-8', 'gnd:4391005-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789506246'] | ['Dweck, Hany Khammis Mohammed', 'Grunwald Kadow, Ilona', 'Heckel, David G.', 'Hansson, Bill S.', 'Friedrich-Schiller-Universität Jena', 'Evolution', 'Taufliege', 'Drosophila', 'Geruchsorgan', 'Terpene', 'Sensorischer Rezeptor', 'Geosmin'] | Document
### Title: ['Drosophila olfactory neuroecology : function and evolution']
### Abstract:
['Olfaction is the single most studied means of insect chemoreception. Many insects are sensitive to olfactory signals that advertise relevant ecological information concerning nutrient resources, competitors, predators, potential mates, and host suitability (Price et al., 2011). The olfactory system of the vinegar fly, Drosophila melanogaster, serves as a genetically and anatomically simple model for studying how sensory input is translated into behavioral output, because only two synapses isolate the input peripheral detection of ecologically relevant olfactory signals from the output behavioral navigation. This genetic and anatomical simplicity of the Drosophila olfactory system allowed us to further our understanding of the Drosophila olfactory neuroecology. Here, we have shown that the vinegar fly, Drosophila melanogaster, has two olfactory pathways, one that underlies the hardwired innate avoidance of harmful microbes and a second pathway for oviposition in Citrus substrates. We also showed that the peripheral odor detection machinery of D. erecta and D. mojavensis have been modified to match the olfactory needs of their respective ecological systems and associated host plants. Thus the findings of this thesis, while most directly pertinent to the advancement of our understanding of the basic science behind olfactory mechanisms, may also be useful in integrated pest management strategies for these and other potential pest insects']
### GND ID:
['gnd:1058617524', 'gnd:1171368399', 'gnd:1192684982', 'gnd:120793342', 'gnd:36164-1', 'gnd:4071050-6', 'gnd:4078168-9', 'gnd:4150708-3', 'gnd:4156903-9', 'gnd:4184779-9', 'gnd:4209106-8', 'gnd:4391005-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789506246']
### GND class:
['Dweck, Hany Khammis Mohammed', 'Grunwald Kadow, Ilona', 'Heckel, David G.', 'Hansson, Bill S.', 'Friedrich-Schiller-Universität Jena', 'Evolution', 'Taufliege', 'Drosophila', 'Geruchsorgan', 'Terpene', 'Sensorischer Rezeptor', 'Geosmin']
<|eot_id|> |
3A789954680.jsonld | ['Granular modernism'] | ["This book understands the way that some Modernist texts put themselves together as a way of pulling themselves apart. In this volume, Beci Carver offers a new way of reading Modernist novels and poems , by drawing attention to the anomalies that make them difficult to summarise or simplify. Carver proposes that rather than trying to find the shapes of narrative or argument in their writing, the 'Granular Modernists' - namely, Joseph Conrad, William Gerhardie, Evelyn Waugh, Henry Green, T.S. Eliot, W.H. Auden, and Samuel Beckett - experiment in certain of their works in finding the shapelessness of a moment in history that increasingly confidently called itself 'modern', which was to call itself shapeless. The project of Modernism in the late nineteenth and the first half of the twentieth century, was to find a story to tell about an era full of beginnings. The project of 'Granular Modernism' was to find a way of turning the inchoateness of the modern moment into art"] | ['gnd:1066586594', 'gnd:4014777-0', 'gnd:4035964-5', 'gnd:4039827-4', 'gnd:4133275-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789954680'] | ['Carver, Beci', 'Englisch', 'Literatur', 'Moderne', 'Modernismus'] | Document
### Title: ['Granular modernism']
### Abstract:
["This book understands the way that some Modernist texts put themselves together as a way of pulling themselves apart. In this volume, Beci Carver offers a new way of reading Modernist novels and poems , by drawing attention to the anomalies that make them difficult to summarise or simplify. Carver proposes that rather than trying to find the shapes of narrative or argument in their writing, the 'Granular Modernists' - namely, Joseph Conrad, William Gerhardie, Evelyn Waugh, Henry Green, T.S. Eliot, W.H. Auden, and Samuel Beckett - experiment in certain of their works in finding the shapelessness of a moment in history that increasingly confidently called itself 'modern', which was to call itself shapeless. The project of Modernism in the late nineteenth and the first half of the twentieth century, was to find a story to tell about an era full of beginnings. The project of 'Granular Modernism' was to find a way of turning the inchoateness of the modern moment into art"]
### GND ID:
['gnd:1066586594', 'gnd:4014777-0', 'gnd:4035964-5', 'gnd:4039827-4', 'gnd:4133275-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A789954680']
### GND class:
['Carver, Beci', 'Englisch', 'Literatur', 'Moderne', 'Modernismus']
<|eot_id|> |
3A790117495.jsonld | ['Flood modeling in spatial data and grid infrastructures'] | ['Spatial data and grid infrastructures manage distributed geographic data, computing, and storage resources from different organizations without centralized control. However, these two infrastructures have evolved separately and use different open standards. This thesis makes a contribution to the implementation of such open standards from spatial data and grid infrastructures in the field of flood modeling. In a first step, and for the first time ever, the process of flood modeling by two-dimensional hydrodynamic simulation — flow model discretization, flood simulation, and results evaluation — is formalized as a sequence of geoprocessing tasks. These geoprocessing tasks are then implemented as geoprocessing grid services. To achieve this, two standards commonly used in spatial data and grid infrastructures, the Web Processing Service (WPS) and the Web Services Resource Framework (WSRF), are harmonized. This harmonization results in a generic procedure for the creation of geoprocessing grid services called Grid-WPS. This procedure is evaluated by two prototypical implementations of flood modeling tasks. The first prototype, a flow model discretization service, employs a new strategy for the parallel creation of large, unstructured, two-dimensional computational meshes based on a high-resolution digital elevation model. Through the application of grid technology, it is shown how large volumes of geographic data from a spatial data infrastructure can efficiently be processed in a distributed computing environment using a geoprocessing grid workflow. The second prototype, a flood simulation service, further demonstrates how to execute a large-scale hydrodynamic simulation on multiple distributed clusters in a grid infrastructure with application of a two-level parallel domain decomposition approach. Together, the flow model discretization service and flood simulation service provide an efficient technology for mapping flood hazards. By adhering to the presented Grid-WPS procedure, the developed services are enabled to coexist in both infrastructures. In this way, they can make use of the provided resources and can also easily be reused in the context of other grid applications or geoprocessing workflows.'] | ['gnd:1055069755', 'gnd:4058275-9', 'gnd:4170297-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790117495'] | ['Kurzbach, Stefan', 'Sturmflut', 'Modellierung'] | Document
### Title: ['Flood modeling in spatial data and grid infrastructures']
### Abstract:
['Spatial data and grid infrastructures manage distributed geographic data, computing, and storage resources from different organizations without centralized control. However, these two infrastructures have evolved separately and use different open standards. This thesis makes a contribution to the implementation of such open standards from spatial data and grid infrastructures in the field of flood modeling. In a first step, and for the first time ever, the process of flood modeling by two-dimensional hydrodynamic simulation — flow model discretization, flood simulation, and results evaluation — is formalized as a sequence of geoprocessing tasks. These geoprocessing tasks are then implemented as geoprocessing grid services. To achieve this, two standards commonly used in spatial data and grid infrastructures, the Web Processing Service (WPS) and the Web Services Resource Framework (WSRF), are harmonized. This harmonization results in a generic procedure for the creation of geoprocessing grid services called Grid-WPS. This procedure is evaluated by two prototypical implementations of flood modeling tasks. The first prototype, a flow model discretization service, employs a new strategy for the parallel creation of large, unstructured, two-dimensional computational meshes based on a high-resolution digital elevation model. Through the application of grid technology, it is shown how large volumes of geographic data from a spatial data infrastructure can efficiently be processed in a distributed computing environment using a geoprocessing grid workflow. The second prototype, a flood simulation service, further demonstrates how to execute a large-scale hydrodynamic simulation on multiple distributed clusters in a grid infrastructure with application of a two-level parallel domain decomposition approach. Together, the flow model discretization service and flood simulation service provide an efficient technology for mapping flood hazards. By adhering to the presented Grid-WPS procedure, the developed services are enabled to coexist in both infrastructures. In this way, they can make use of the provided resources and can also easily be reused in the context of other grid applications or geoprocessing workflows.']
### GND ID:
['gnd:1055069755', 'gnd:4058275-9', 'gnd:4170297-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790117495']
### GND class:
['Kurzbach, Stefan', 'Sturmflut', 'Modellierung']
<|eot_id|> |
3A790298481.jsonld | ['Optimierung und Anwendung von Strategien zur Herstellung von TGF-[beta]1 in eukaryotischen Zellen'] | ['Wachstumsfaktoren, TGF-beta1, rekombinante Proteine, transiente Transfektion. - Growth factors, recombinant proteins, transient transfection'] | ['gnd:1058613502', 'gnd:4020136-3', 'gnd:4185874-8', 'gnd:4332883-0', 'gnd:4404907-9', 'gnd:4665329-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790298481'] | ['Abdulkerim, Estabraq', 'Genexpression', 'Transfektion', 'In-vitro-Kultur', 'Transforming Growth Factor beta 1', 'Stammzelle'] | Document
### Title: ['Optimierung und Anwendung von Strategien zur Herstellung von TGF-[beta]1 in eukaryotischen Zellen']
### Abstract:
['Wachstumsfaktoren, TGF-beta1, rekombinante Proteine, transiente Transfektion. - Growth factors, recombinant proteins, transient transfection']
### GND ID:
['gnd:1058613502', 'gnd:4020136-3', 'gnd:4185874-8', 'gnd:4332883-0', 'gnd:4404907-9', 'gnd:4665329-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790298481']
### GND class:
['Abdulkerim, Estabraq', 'Genexpression', 'Transfektion', 'In-vitro-Kultur', 'Transforming Growth Factor beta 1', 'Stammzelle']
<|eot_id|> |
3A790303531.jsonld | ['Development of suitable in vitro models of the bronchial epithelium for inhalation toxicology'] | ['In vitro models, airway diseases, co-culture cell systems, inhalation toxicology. - In vitro-Modelle, Co-Kultur Zellsysteme, Inhalationstoxikologie, Atemwegerkrankungen'] | ['gnd:1058759752', 'gnd:4036660-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790303531'] | ['Rach, Jessica', 'Lungenkrankheit'] | Document
### Title: ['Development of suitable in vitro models of the bronchial epithelium for inhalation toxicology']
### Abstract:
['In vitro models, airway diseases, co-culture cell systems, inhalation toxicology. - In vitro-Modelle, Co-Kultur Zellsysteme, Inhalationstoxikologie, Atemwegerkrankungen']
### GND ID:
['gnd:1058759752', 'gnd:4036660-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790303531']
### GND class:
['Rach, Jessica', 'Lungenkrankheit']
<|eot_id|> |
3A790304481.jsonld | ['Entwicklung und Anwendung innovativer Methoden in der Säugerzellkultivierung im Bioreaktor für die Herstellung von pharmazeutischen Proteinen'] | ['Säugetierzellen, Affinitätsmatrixfärbemethode, 2D-Fluoreszenzspektroskopie, Sauerstoffaufnahmerate. - Mammalian cells, cell-surface affinity matrix, 2D-fluorescence spectroscopy, oxygen uptake rate'] | ['gnd:136475434', 'gnd:4006780-4', 'gnd:4017701-4', 'gnd:4067547-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790304481'] | ['Behr, Larissa Christiane', 'Bioreaktor', 'Fluoreszenzspektroskopie', 'Zellkultur'] | Document
### Title: ['Entwicklung und Anwendung innovativer Methoden in der Säugerzellkultivierung im Bioreaktor für die Herstellung von pharmazeutischen Proteinen']
### Abstract:
['Säugetierzellen, Affinitätsmatrixfärbemethode, 2D-Fluoreszenzspektroskopie, Sauerstoffaufnahmerate. - Mammalian cells, cell-surface affinity matrix, 2D-fluorescence spectroscopy, oxygen uptake rate']
### GND ID:
['gnd:136475434', 'gnd:4006780-4', 'gnd:4017701-4', 'gnd:4067547-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790304481']
### GND class:
['Behr, Larissa Christiane', 'Bioreaktor', 'Fluoreszenzspektroskopie', 'Zellkultur']
<|eot_id|> |
3A790308460.jsonld | ['Entwicklung und Optimierung eines Fluoreszenzsensors zum Monitoring von Sauerteigfermentationen'] | ['Sauerteigfermentation, Fluoreszenzspektroskopie, Onlineprozessbeobachtung, multivariate Datenauswertung. - Sourdough fermentation, fluorescence spectroscopy, online process monitoring, multivariate data analysis'] | ['gnd:1018141618', 'gnd:4051816-4', 'gnd:4129537-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790308460'] | ['Grote, Bianca', 'Sauerteig', 'Fermentation'] | Document
### Title: ['Entwicklung und Optimierung eines Fluoreszenzsensors zum Monitoring von Sauerteigfermentationen']
### Abstract:
['Sauerteigfermentation, Fluoreszenzspektroskopie, Onlineprozessbeobachtung, multivariate Datenauswertung. - Sourdough fermentation, fluorescence spectroscopy, online process monitoring, multivariate data analysis']
### GND ID:
['gnd:1018141618', 'gnd:4051816-4', 'gnd:4129537-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A790308460']
### GND class:
['Grote, Bianca', 'Sauerteig', 'Fermentation']
<|eot_id|> |
3A79080784X.jsonld | ['Bondholder relations activities in Germany : empirical studies of the extent and effectiveness of corporate disclosure to the Bond Market'] | [['The German market for corporate bonds has experienced an unprecedented growth over the last decade. As a growing number of German firms have seized the opportunity to issue debt securities to the market, the need arises to evaluate their attempts to provide bondholders with private corporate information. This doctoral thesis centers on a research interest concerning the extent and effectiveness of corporate disclosure directed at the German bond market. It delivers unprecedented insights into bondholder relations practices and is thought to establish this topic as a research field that is complementary to previous work on shareholder-related disclosure. Taking information asymmetries between firms and bondholders as a basis, the empirical analyses are based on various arguments from the voluntary disclosure theory as well as from principal-agency and related frameworks. In essence, most parts of the thesis follow the key assumption that bondholders demand higher premiums for opaqueness and potentially detrimental behavior on behalf of a bond issuer’s management. The analyses deliver new insights into the role of corporate disclosure and close a gap between bondholder relations and financial as well as shareholder-related disclosure. They contribute to the stream of research that is concerned with corporate disclosure and its relationship to the cost of capital, the cost of debt, and even more specifically the yield (spread) of corporate bonds.', 'SWD-Schlagwörter: Unternehmen, Industrieobligationen, Anleihe, Publizität, Kommunikation. - Freie Schlagwörter (Englisch): Corporate Bond, Bond Market, Corporate Disclosure, Bondholder Relations Market,']] | ['gnd:1053681593', 'gnd:4018417-1', 'gnd:4177794-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79080784X'] | ['Janner, Steve', 'Fremdfinanzierung', 'Rentenmarkt'] | Document
### Title: ['Bondholder relations activities in Germany : empirical studies of the extent and effectiveness of corporate disclosure to the Bond Market']
### Abstract:
[['The German market for corporate bonds has experienced an unprecedented growth over the last decade. As a growing number of German firms have seized the opportunity to issue debt securities to the market, the need arises to evaluate their attempts to provide bondholders with private corporate information. This doctoral thesis centers on a research interest concerning the extent and effectiveness of corporate disclosure directed at the German bond market. It delivers unprecedented insights into bondholder relations practices and is thought to establish this topic as a research field that is complementary to previous work on shareholder-related disclosure. Taking information asymmetries between firms and bondholders as a basis, the empirical analyses are based on various arguments from the voluntary disclosure theory as well as from principal-agency and related frameworks. In essence, most parts of the thesis follow the key assumption that bondholders demand higher premiums for opaqueness and potentially detrimental behavior on behalf of a bond issuer’s management. The analyses deliver new insights into the role of corporate disclosure and close a gap between bondholder relations and financial as well as shareholder-related disclosure. They contribute to the stream of research that is concerned with corporate disclosure and its relationship to the cost of capital, the cost of debt, and even more specifically the yield (spread) of corporate bonds.', 'SWD-Schlagwörter: Unternehmen, Industrieobligationen, Anleihe, Publizität, Kommunikation. - Freie Schlagwörter (Englisch): Corporate Bond, Bond Market, Corporate Disclosure, Bondholder Relations Market,']]
### GND ID:
['gnd:1053681593', 'gnd:4018417-1', 'gnd:4177794-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79080784X']
### GND class:
['Janner, Steve', 'Fremdfinanzierung', 'Rentenmarkt']
<|eot_id|> |
3A791044998.jsonld | ['Entwicklung und Anwendung innovativer Methoden in der Säugerzellkultivierung im Bioreaktor für die Herstellung von pharmazeutischen Proteinen'] | ['Säugetierzellen, Affinitätsmatrixfärbemethode, 2D-Fluoreszenzspektroskopie, Sauerstoffaufnahmerate. - Mammalian cells, cell-surface affinity matrix, 2D-fluorescence spectroscopy, oxygen uptake rate'] | ['gnd:136475434', 'gnd:4006780-4', 'gnd:4017701-4', 'gnd:4067547-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791044998'] | ['Behr, Larissa Christiane', 'Bioreaktor', 'Fluoreszenzspektroskopie', 'Zellkultur'] | Document
### Title: ['Entwicklung und Anwendung innovativer Methoden in der Säugerzellkultivierung im Bioreaktor für die Herstellung von pharmazeutischen Proteinen']
### Abstract:
['Säugetierzellen, Affinitätsmatrixfärbemethode, 2D-Fluoreszenzspektroskopie, Sauerstoffaufnahmerate. - Mammalian cells, cell-surface affinity matrix, 2D-fluorescence spectroscopy, oxygen uptake rate']
### GND ID:
['gnd:136475434', 'gnd:4006780-4', 'gnd:4017701-4', 'gnd:4067547-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791044998']
### GND class:
['Behr, Larissa Christiane', 'Bioreaktor', 'Fluoreszenzspektroskopie', 'Zellkultur']
<|eot_id|> |
3A791098990.jsonld | ['Analyse und Synthese von zyklischen Herstellungsprozessen artifizieller Diversity Covering (DiCo) Malariavakzinkandidaten'] | ['Malaria-Impfstoffkandidaten, Pichia pastoris, sequentielle Produktion, design of experiments, Expressionsmodellierung und Prozesssimulation. - Malaria vaccine candidates, sequential production, expression modeling and process simulation'] | ['gnd:1058616099', 'gnd:4026655-2', 'gnd:4037197-9', 'gnd:4307166-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791098990'] | ['Martens, Sanja', 'Impfstoff', 'Malaria', 'Bioverfahrenstechnik'] | Document
### Title: ['Analyse und Synthese von zyklischen Herstellungsprozessen artifizieller Diversity Covering (DiCo) Malariavakzinkandidaten']
### Abstract:
['Malaria-Impfstoffkandidaten, Pichia pastoris, sequentielle Produktion, design of experiments, Expressionsmodellierung und Prozesssimulation. - Malaria vaccine candidates, sequential production, expression modeling and process simulation']
### GND ID:
['gnd:1058616099', 'gnd:4026655-2', 'gnd:4037197-9', 'gnd:4307166-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791098990']
### GND class:
['Martens, Sanja', 'Impfstoff', 'Malaria', 'Bioverfahrenstechnik']
<|eot_id|> |
3A791572552.jsonld | ['Bridgeland stability conditions in algebra, geometry and physics'] | [['Zusammenfassung: In the first part we study stability conditions on projective Kummer surfaces. In the second part we us stability conditions to prove results for refined Donaldson-Thomas invarinats associated to quivers with potential', 'Zusammenfassung: In ersten Teil studieren wir Stabilitätsbedingungen auf projektiven Kummer Flächen. Im zweiten Teil nutzen wir Stabilitätsbedigungen um Resultate für verfeinerte Donaldson-Thomas-Invarianten assoziiert zu Köchern mit Potential zu beweisen']] | ['gnd:1054561168', 'gnd:4056693-6', 'gnd:4162958-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791572552'] | ['Engenhorst, Jan Magnus Matthias', 'Stabilität', 'K 3- Fläche'] | Document
### Title: ['Bridgeland stability conditions in algebra, geometry and physics']
### Abstract:
[['Zusammenfassung: In the first part we study stability conditions on projective Kummer surfaces. In the second part we us stability conditions to prove results for refined Donaldson-Thomas invarinats associated to quivers with potential', 'Zusammenfassung: In ersten Teil studieren wir Stabilitätsbedingungen auf projektiven Kummer Flächen. Im zweiten Teil nutzen wir Stabilitätsbedigungen um Resultate für verfeinerte Donaldson-Thomas-Invarianten assoziiert zu Köchern mit Potential zu beweisen']]
### GND ID:
['gnd:1054561168', 'gnd:4056693-6', 'gnd:4162958-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791572552']
### GND class:
['Engenhorst, Jan Magnus Matthias', 'Stabilität', 'K 3- Fläche']
<|eot_id|> |
3A791575012.jsonld | ['Three Essays on the Econometrics of Survey Expectations Data'] | ["This dissertation consists of three essays that have a common focus on the econometrics of survey expectations data. Such data play a crucial role in economics. First, as most decisions depend on expectations, these data facilitate a better understanding of economic dynamics. Second, survey data provide information that is otherwise unavailable, e.g. the economic expectations of professional forecasters or firms' hiring, investment and production activities. This thesis contributes to the relevant literature by considering novel aspects in the measurement of expectations, and by proposing a new approach to exploit survey expectations data in forecasting."] | ['gnd:4027503-6', 'gnd:4067486-1', 'gnd:4132280-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791575012'] | ['Interview', 'Zeitreihenanalyse', 'Ökonometrie'] | Document
### Title: ['Three Essays on the Econometrics of Survey Expectations Data']
### Abstract:
["This dissertation consists of three essays that have a common focus on the econometrics of survey expectations data. Such data play a crucial role in economics. First, as most decisions depend on expectations, these data facilitate a better understanding of economic dynamics. Second, survey data provide information that is otherwise unavailable, e.g. the economic expectations of professional forecasters or firms' hiring, investment and production activities. This thesis contributes to the relevant literature by considering novel aspects in the measurement of expectations, and by proposing a new approach to exploit survey expectations data in forecasting."]
### GND ID:
['gnd:4027503-6', 'gnd:4067486-1', 'gnd:4132280-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791575012']
### GND class:
['Interview', 'Zeitreihenanalyse', 'Ökonometrie']
<|eot_id|> |
3A79158805X.jsonld | ['Germany’s future electors : developments of the German electorate in times of demographic change'] | ['The influence of legal and demographic changes on the development of the electorate -- Demographic projections: The influence of demographic trends on the development of the electorate -- Policy scenarios: The influence of legal changes on the development of the electorate -- The development of the German electorate: Trends and consequences'] | ['gnd:1060505436', 'gnd:4006292-2', 'gnd:4009016-4', 'gnd:4011882-4', 'gnd:4064144-2', 'gnd:4064302-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79158805X'] | ['Sánchez Gassen, Nora E.', 'Bevölkerungsentwicklung', 'Bundestagswahl', 'Deutschland', 'Wähler', 'Wahlrecht'] | Document
### Title: ['Germany’s future electors : developments of the German electorate in times of demographic change']
### Abstract:
['The influence of legal and demographic changes on the development of the electorate -- Demographic projections: The influence of demographic trends on the development of the electorate -- Policy scenarios: The influence of legal changes on the development of the electorate -- The development of the German electorate: Trends and consequences']
### GND ID:
['gnd:1060505436', 'gnd:4006292-2', 'gnd:4009016-4', 'gnd:4011882-4', 'gnd:4064144-2', 'gnd:4064302-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79158805X']
### GND class:
['Sánchez Gassen, Nora E.', 'Bevölkerungsentwicklung', 'Bundestagswahl', 'Deutschland', 'Wähler', 'Wahlrecht']
<|eot_id|> |
3A791684482.jsonld | ['Structural and magnetic investigations of two spreading systems around the Rodriguez Triple Junction with respect to hydrothermal activities'] | ['Mid-ocean ridges, hydrothermal vent fields, spreading rates. - Mittelozeanische Rücken, Hydrothermalfelder, Spreizungsraten'] | ['gnd:4317501-6', 'gnd:4381336-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791684482'] | ['Mittelozeanischer Rücken', 'Hydrothermalgebiet'] | Document
### Title: ['Structural and magnetic investigations of two spreading systems around the Rodriguez Triple Junction with respect to hydrothermal activities']
### Abstract:
['Mid-ocean ridges, hydrothermal vent fields, spreading rates. - Mittelozeanische Rücken, Hydrothermalfelder, Spreizungsraten']
### GND ID:
['gnd:4317501-6', 'gnd:4381336-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A791684482']
### GND class:
['Mittelozeanischer Rücken', 'Hydrothermalgebiet']
<|eot_id|> |
3A792072618.jsonld | ['Untersuchung zur Steigerbarkeit von Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken'] | [['In the present work it is investigated to what extend the flexibility, performance, and extensibility of automated guided vehicle systems can be increased by the use of decentralized control techniques. The control system is modeled as a multi agent system in which each vehicle and each station is represented by an agent. The order disposition is modeled as an auction process which can be adapted to the desired system behavior. In order to achieve a conflict free routing of all the vehicles a decentralized algorithm was implemented. The system behavior is enhanced further by the use of negotiations. The present work describes the modeling of the system as well as the implementation and the evaluation. The evaluation is achieved through multiple simulation experiments. <engl.>', 'In der vorliegenden Arbeit wird untersucht, in wieweit Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken gesteigert werden können. Die Modellierung der Steuerung erfolgt durch ein Multi-Agenten-System in welchem sowohl die Fahrzeuge als auch die Auftragsvergabestationen durch Agenten modelliert werden. Die Auftragsvergabe erfolgt durch verschiedene Auktionsverfahren die an die gewünschten Systemeigenschaften angepasst werden können. Für das konfliktfreie Berechnen der Routen wurde ein entsprechender Algorithmus dezentral umgesetzt. Eine weitere Verbesserung der Systemperformanz wird durch Verhandlungen zwischen den Agenten erreicht. Neben der Beschreibung der Modellierung wird in der vorliegenden Arbeit ebenfalls die Implementation sowie die Validierung der Implementation beschrieben. Letztere geschieht mit Hilfe von mehreren Simulationsexperimenten. <dt.>']] | ['gnd:1059140837', 'gnd:129368970', 'gnd:4016284-9', 'gnd:4210741-6', 'gnd:4269073-0', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792072618'] | ['Schwarz, Christoph', 'Sauer, Jürgen', 'Fahrerloses Transportsystem', 'Dezentrale Steuerung', 'Routing', 'Mehragentensystem'] | Document
### Title: ['Untersuchung zur Steigerbarkeit von Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken']
### Abstract:
[['In the present work it is investigated to what extend the flexibility, performance, and extensibility of automated guided vehicle systems can be increased by the use of decentralized control techniques. The control system is modeled as a multi agent system in which each vehicle and each station is represented by an agent. The order disposition is modeled as an auction process which can be adapted to the desired system behavior. In order to achieve a conflict free routing of all the vehicles a decentralized algorithm was implemented. The system behavior is enhanced further by the use of negotiations. The present work describes the modeling of the system as well as the implementation and the evaluation. The evaluation is achieved through multiple simulation experiments. <engl.>', 'In der vorliegenden Arbeit wird untersucht, in wieweit Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken gesteigert werden können. Die Modellierung der Steuerung erfolgt durch ein Multi-Agenten-System in welchem sowohl die Fahrzeuge als auch die Auftragsvergabestationen durch Agenten modelliert werden. Die Auftragsvergabe erfolgt durch verschiedene Auktionsverfahren die an die gewünschten Systemeigenschaften angepasst werden können. Für das konfliktfreie Berechnen der Routen wurde ein entsprechender Algorithmus dezentral umgesetzt. Eine weitere Verbesserung der Systemperformanz wird durch Verhandlungen zwischen den Agenten erreicht. Neben der Beschreibung der Modellierung wird in der vorliegenden Arbeit ebenfalls die Implementation sowie die Validierung der Implementation beschrieben. Letztere geschieht mit Hilfe von mehreren Simulationsexperimenten. <dt.>']]
### GND ID:
['gnd:1059140837', 'gnd:129368970', 'gnd:4016284-9', 'gnd:4210741-6', 'gnd:4269073-0', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792072618']
### GND class:
['Schwarz, Christoph', 'Sauer, Jürgen', 'Fahrerloses Transportsystem', 'Dezentrale Steuerung', 'Routing', 'Mehragentensystem']
<|eot_id|> |
3A792084829.jsonld | ['Global players - local struggles : spatial dynamics of industrialisation and social change in peri-urban Chennai, India'] | ['Empirical research on the societal and spatial impacts of global change has concentrated either on rural or urban contexts, especially on megacities. The peri?urban spaces in between are largely left unnoticed, although experiencing the most profound and dynamic transformations. This book presents the first comprehensive study on spatial dynamics of industrial development and social change in this context, taking peri-urban Chennai, the thriving industrial hub in southern India, as an example.'] | ['gnd:1045582913', 'gnd:4066438-7', 'gnd:4066446-6', 'gnd:5351481-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792084829'] | ['Homm, Sebastian', 'Wirtschaftsentwicklung', 'Wirtschaftsgeografie', 'Chennai'] | Document
### Title: ['Global players - local struggles : spatial dynamics of industrialisation and social change in peri-urban Chennai, India']
### Abstract:
['Empirical research on the societal and spatial impacts of global change has concentrated either on rural or urban contexts, especially on megacities. The peri?urban spaces in between are largely left unnoticed, although experiencing the most profound and dynamic transformations. This book presents the first comprehensive study on spatial dynamics of industrial development and social change in this context, taking peri-urban Chennai, the thriving industrial hub in southern India, as an example.']
### GND ID:
['gnd:1045582913', 'gnd:4066438-7', 'gnd:4066446-6', 'gnd:5351481-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792084829']
### GND class:
['Homm, Sebastian', 'Wirtschaftsentwicklung', 'Wirtschaftsgeografie', 'Chennai']
<|eot_id|> |
3A792487095.jsonld | ['Structural response of stranded ships'] | [['The thesis reports on different methods to assess the consequences of soft grounding accidents, called stranding, to the ship structure in tidal waters. The critical combinations of stranding position, tidal range and load case are calculated as well as the complete global and local damage process with the finite element method. Moment-shear force interaction curves based on the combined loading conditions are given to evaluate the influence of the shear force on the ultimate hull girder strength. The proposed methods are applicable to any ship type for calculating real stranding accidents. Very good conformance with one known accident is achieved.', 'In der Dissertation werden verschiedene Methoden vorgestellt, die die Strukturantwort des Schiffes bei weicher Grundberührung, auch Strandung genannt, in Tidegewässern berechnen. Die kritischen Kombinationen aus Strandungsposition, Tideeffekten und Beladung sowie globale und lokale Schäden u.a. unter Verwendung der Finiten-Elemente Methode werden berechnet. Der Einfluss der Querkraft auf das Grenztraglastmoment wird über neue Momenten-Querkraft-Interaktionskurven bestimmt. Die Berechnung eines wirklichen Strandungsunfalls mit den vorgeschlagenen Methoden zeigt sehr gute Übereinstimmungen.']] | ['gnd:10194333-7', 'gnd:1037192761', 'gnd:108609197', 'gnd:1138134619', 'gnd:4060581-4', 'gnd:4113241-5', 'gnd:4198073-6', 'gnd:4511937-5', 'gnd:4711974-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792487095'] | ['Technische Universität Hamburg-Harburg, Institut für Konstruktion und Festigkeit von Schiffen', 'Grabe, Jürgen', 'Lehmann, Eike', 'Zipfel, Bernadette', 'Tragfähigkeit', 'Containerschiff', 'Strandung', 'Online-Ressource', 'Hydrostatische Beanspruchung'] | Document
### Title: ['Structural response of stranded ships']
### Abstract:
[['The thesis reports on different methods to assess the consequences of soft grounding accidents, called stranding, to the ship structure in tidal waters. The critical combinations of stranding position, tidal range and load case are calculated as well as the complete global and local damage process with the finite element method. Moment-shear force interaction curves based on the combined loading conditions are given to evaluate the influence of the shear force on the ultimate hull girder strength. The proposed methods are applicable to any ship type for calculating real stranding accidents. Very good conformance with one known accident is achieved.', 'In der Dissertation werden verschiedene Methoden vorgestellt, die die Strukturantwort des Schiffes bei weicher Grundberührung, auch Strandung genannt, in Tidegewässern berechnen. Die kritischen Kombinationen aus Strandungsposition, Tideeffekten und Beladung sowie globale und lokale Schäden u.a. unter Verwendung der Finiten-Elemente Methode werden berechnet. Der Einfluss der Querkraft auf das Grenztraglastmoment wird über neue Momenten-Querkraft-Interaktionskurven bestimmt. Die Berechnung eines wirklichen Strandungsunfalls mit den vorgeschlagenen Methoden zeigt sehr gute Übereinstimmungen.']]
### GND ID:
['gnd:10194333-7', 'gnd:1037192761', 'gnd:108609197', 'gnd:1138134619', 'gnd:4060581-4', 'gnd:4113241-5', 'gnd:4198073-6', 'gnd:4511937-5', 'gnd:4711974-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792487095']
### GND class:
['Technische Universität Hamburg-Harburg, Institut für Konstruktion und Festigkeit von Schiffen', 'Grabe, Jürgen', 'Lehmann, Eike', 'Zipfel, Bernadette', 'Tragfähigkeit', 'Containerschiff', 'Strandung', 'Online-Ressource', 'Hydrostatische Beanspruchung']
<|eot_id|> |
3A792517083.jsonld | ['Simultaneous measurement of spectral sky radiance : development, characterization and validation of a non-scanning multidirectional spectroradiometer (MUDIS)'] | ['UV spectroradiometry, UV sky radiance, UV imaging spectroradiometer. - UV Spektroradiometrie, UV Strahldichte, UV Imaging Spektroradiometer'] | ['gnd:4139254-1', 'gnd:4186733-6', 'gnd:4218300-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792517083'] | ['Sonnenstrahlung', 'Ultraviolett', 'Spektroradiometrie'] | Document
### Title: ['Simultaneous measurement of spectral sky radiance : development, characterization and validation of a non-scanning multidirectional spectroradiometer (MUDIS)']
### Abstract:
['UV spectroradiometry, UV sky radiance, UV imaging spectroradiometer. - UV Spektroradiometrie, UV Strahldichte, UV Imaging Spektroradiometer']
### GND ID:
['gnd:4139254-1', 'gnd:4186733-6', 'gnd:4218300-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A792517083']
### GND class:
['Sonnenstrahlung', 'Ultraviolett', 'Spektroradiometrie']
<|eot_id|> |
3A793002923.jsonld | ['Laser power increase for GEO 600 : commissioning aspects towards an operation of GEO 600 at high laser power'] | ['Gravitational wave detector, laser power increase, stray light. - Gravitationswellendetektor, Laserleistungserhöhung, Streulicht'] | ['gnd:105860175X', 'gnd:1098550242', 'gnd:4034610-9', 'gnd:4129854-8', 'gnd:4140518-3', 'gnd:4155413-9', 'gnd:4167306-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793002923'] | ['Affeldt, Christoph', 'GEO 600 (Astronomie)', 'Laser', 'Streulicht', 'Michelson-Interferometer', 'Frequenzstabilität', 'Leistungssteigerung'] | Document
### Title: ['Laser power increase for GEO 600 : commissioning aspects towards an operation of GEO 600 at high laser power']
### Abstract:
['Gravitational wave detector, laser power increase, stray light. - Gravitationswellendetektor, Laserleistungserhöhung, Streulicht']
### GND ID:
['gnd:105860175X', 'gnd:1098550242', 'gnd:4034610-9', 'gnd:4129854-8', 'gnd:4140518-3', 'gnd:4155413-9', 'gnd:4167306-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793002923']
### GND class:
['Affeldt, Christoph', 'GEO 600 (Astronomie)', 'Laser', 'Streulicht', 'Michelson-Interferometer', 'Frequenzstabilität', 'Leistungssteigerung']
<|eot_id|> |
3A793015901.jsonld | ['The cosmological constant, branes and non-geometry'] | ['String theory, compactification, cosmological constant, D-branes, string dualities. - Stringtheorie, Kompaktifizierung, kosmologische Konstante, D-Branen, Stringdualitäten'] | ['gnd:1058617192', 'gnd:4164859-6', 'gnd:4224278-2', 'gnd:4571605-5', 'gnd:4608630-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793015901'] | ['Gautason, Fridrik Freyr', 'Kompaktifizierung', 'Stringtheorie', 'Kosmologische Konstante', 'D-Brane'] | Document
### Title: ['The cosmological constant, branes and non-geometry']
### Abstract:
['String theory, compactification, cosmological constant, D-branes, string dualities. - Stringtheorie, Kompaktifizierung, kosmologische Konstante, D-Branen, Stringdualitäten']
### GND ID:
['gnd:1058617192', 'gnd:4164859-6', 'gnd:4224278-2', 'gnd:4571605-5', 'gnd:4608630-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793015901']
### GND class:
['Gautason, Fridrik Freyr', 'Kompaktifizierung', 'Stringtheorie', 'Kosmologische Konstante', 'D-Brane']
<|eot_id|> |
3A793913985.jsonld | ['Untersuchung zur Steigerbarkeit von Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken'] | [['In the present work it is investigated to what extend the flexibility, performance, and extensibility of automated guided vehicle systems can be increased by the use of decentralized control techniques. The control system is modeled as a multi agent system in which each vehicle and each station is represented by an agent. The order disposition is modeled as an auction process which can be adapted to the desired system behavior. In order to achieve a conflict free routing of all the vehicles a decentralized algorithm was implemented. The system behavior is enhanced further by the use of negotiations. The present work describes the modeling of the system as well as the implementation and the evaluation. The evaluation is achieved through multiple simulation experiments. <engl.>', 'In der vorliegenden Arbeit wird untersucht, in wieweit Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken gesteigert werden können. Die Modellierung der Steuerung erfolgt durch ein Multi-Agenten-System in welchem sowohl die Fahrzeuge als auch die Auftragsvergabestationen durch Agenten modelliert werden. Die Auftragsvergabe erfolgt durch verschiedene Auktionsverfahren die an die gewünschten Systemeigenschaften angepasst werden können. Für das konfliktfreie Berechnen der Routen wurde ein entsprechender Algorithmus dezentral umgesetzt. Eine weitere Verbesserung der Systemperformanz wird durch Verhandlungen zwischen den Agenten erreicht. Neben der Beschreibung der Modellierung wird in der vorliegenden Arbeit ebenfalls die Implementation sowie die Validierung der Implementation beschrieben. Letztere geschieht mit Hilfe von mehreren Simulationsexperimenten. <dt.>']] | ['gnd:129368970', 'gnd:4016284-9', 'gnd:4210741-6', 'gnd:4269073-0', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793913985'] | ['Sauer, Jürgen', 'Fahrerloses Transportsystem', 'Dezentrale Steuerung', 'Routing', 'Mehragentensystem'] | Document
### Title: ['Untersuchung zur Steigerbarkeit von Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken']
### Abstract:
[['In the present work it is investigated to what extend the flexibility, performance, and extensibility of automated guided vehicle systems can be increased by the use of decentralized control techniques. The control system is modeled as a multi agent system in which each vehicle and each station is represented by an agent. The order disposition is modeled as an auction process which can be adapted to the desired system behavior. In order to achieve a conflict free routing of all the vehicles a decentralized algorithm was implemented. The system behavior is enhanced further by the use of negotiations. The present work describes the modeling of the system as well as the implementation and the evaluation. The evaluation is achieved through multiple simulation experiments. <engl.>', 'In der vorliegenden Arbeit wird untersucht, in wieweit Flexibilität, Performanz und Erweiterbarkeit von Fahrerlosen Transportsystemen durch den Einsatz dezentraler Steuerungstechniken gesteigert werden können. Die Modellierung der Steuerung erfolgt durch ein Multi-Agenten-System in welchem sowohl die Fahrzeuge als auch die Auftragsvergabestationen durch Agenten modelliert werden. Die Auftragsvergabe erfolgt durch verschiedene Auktionsverfahren die an die gewünschten Systemeigenschaften angepasst werden können. Für das konfliktfreie Berechnen der Routen wurde ein entsprechender Algorithmus dezentral umgesetzt. Eine weitere Verbesserung der Systemperformanz wird durch Verhandlungen zwischen den Agenten erreicht. Neben der Beschreibung der Modellierung wird in der vorliegenden Arbeit ebenfalls die Implementation sowie die Validierung der Implementation beschrieben. Letztere geschieht mit Hilfe von mehreren Simulationsexperimenten. <dt.>']]
### GND ID:
['gnd:129368970', 'gnd:4016284-9', 'gnd:4210741-6', 'gnd:4269073-0', 'gnd:4389058-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A793913985']
### GND class:
['Sauer, Jürgen', 'Fahrerloses Transportsystem', 'Dezentrale Steuerung', 'Routing', 'Mehragentensystem']
<|eot_id|> |
3A794081487.jsonld | ['Interaktion zwischen flüssigem Silicium und mit Siliciumnitrid beschichtetem Quarz'] | ['Zusammenfassung: The topic of the presented work is the directional solidification of silicon for photovoltaic applications. The solidification of silicon is done in fused silica crucibles which are coated with silicon nitride. By the application of silicon nitride the sticking of silicon to the crucible is prevented. The sticking of the silicon can cause complete failure of the crystallization. The drawbacks are the impurities in Si3N4 and SiO2 which reduce the silicon material quality near the crucible. Aim of the presented work was to study the interaction between the silicon and coated quartz crucible. The work is divided into two major topics'] | ['gnd:105822431X', 'gnd:4033215-9', 'gnd:4077445-4', 'gnd:4121476-6', 'gnd:4456229-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794081487'] | ['Schumann, Mark', 'Kristallisation', 'Silicium', 'Fotovoltaik', 'Gerichtete Erstarrung'] | Document
### Title: ['Interaktion zwischen flüssigem Silicium und mit Siliciumnitrid beschichtetem Quarz']
### Abstract:
['Zusammenfassung: The topic of the presented work is the directional solidification of silicon for photovoltaic applications. The solidification of silicon is done in fused silica crucibles which are coated with silicon nitride. By the application of silicon nitride the sticking of silicon to the crucible is prevented. The sticking of the silicon can cause complete failure of the crystallization. The drawbacks are the impurities in Si3N4 and SiO2 which reduce the silicon material quality near the crucible. Aim of the presented work was to study the interaction between the silicon and coated quartz crucible. The work is divided into two major topics']
### GND ID:
['gnd:105822431X', 'gnd:4033215-9', 'gnd:4077445-4', 'gnd:4121476-6', 'gnd:4456229-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794081487']
### GND class:
['Schumann, Mark', 'Kristallisation', 'Silicium', 'Fotovoltaik', 'Gerichtete Erstarrung']
<|eot_id|> |
3A794249124.jsonld | ['Globale klassische Lösungen nichtlinearer parabolischer Probleme mit dynamischen Randbedingungen in einer Raumdimension'] | ['Quasilinear parabolic problems, classical solutions, global existence, dynamic boundary condition. - Quasilineare parabolische Probleme, klassische Lösungen, globale Existenz, dynamische Randbedingung'] | ['gnd:1058615556', 'gnd:4253347-8', 'gnd:4725395-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794249124'] | ['Gvelesiani, Simon', 'Quasilineare parabolische Differentialgleichung', 'Dynamische Randbedingung'] | Document
### Title: ['Globale klassische Lösungen nichtlinearer parabolischer Probleme mit dynamischen Randbedingungen in einer Raumdimension']
### Abstract:
['Quasilinear parabolic problems, classical solutions, global existence, dynamic boundary condition. - Quasilineare parabolische Probleme, klassische Lösungen, globale Existenz, dynamische Randbedingung']
### GND ID:
['gnd:1058615556', 'gnd:4253347-8', 'gnd:4725395-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794249124']
### GND class:
['Gvelesiani, Simon', 'Quasilineare parabolische Differentialgleichung', 'Dynamische Randbedingung']
<|eot_id|> |
3A794321771.jsonld | ['Encrypting the past : the German-Jewish Holocaust novel of the first generation'] | ['Encrypting the Past puts forward the interpretative category of the first-generation German-Jewish Holocaust novel and examines its representational strategies. With reference to works by H.G. Adler, Jenny Aloni, Elisabeth Augustin, Erich Fried, and Wolfgang Hildesheimer, and a concluding section on W.G. Sebald, it shows how Holocaust literature was being written decades before postwar authors such as Sebald were credited with having found new ways of reflecting the unspeakable. It demonstrates that, before the theoretical debate over the fundamental representability of the Holocaust was even fully under way, first-generation authors were already translating un-narratable trauma into a literary strategy of un-narrating: a strategy of encrypting the Holocaust into the form and structure of their texts. The implications of treating these writers as a set, and their body of work as a hitherto unacknowledged category of Holocaust fiction, go well beyond drawing attention to a number of important but critically neglected authors. This study frames the analysis of first-generation narrative strategies in the broader debate on the ethics and aesthetics of Holocaust writing. In revealing how certain kinds of testimony have been privileged above others in international Holocaust studies, it raises questions of a more general nature concerning canon formation and our theoretical responses to the Holocaust. In considering foremost among these responses the theory of deconstruction and trauma theory, it finally invites a re-examination of the relationship between the (post-)modern and trauma.'] | ['gnd:105858460X', 'gnd:4050479-7', 'gnd:4113292-0', 'gnd:4122228-3', 'gnd:4373760-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794321771'] | ['Gwyer, Kirstin', 'Roman', 'Deutsch', 'Judenvernichtung (Motiv)', 'Schreiben nach Auschwitz'] | Document
### Title: ['Encrypting the past : the German-Jewish Holocaust novel of the first generation']
### Abstract:
['Encrypting the Past puts forward the interpretative category of the first-generation German-Jewish Holocaust novel and examines its representational strategies. With reference to works by H.G. Adler, Jenny Aloni, Elisabeth Augustin, Erich Fried, and Wolfgang Hildesheimer, and a concluding section on W.G. Sebald, it shows how Holocaust literature was being written decades before postwar authors such as Sebald were credited with having found new ways of reflecting the unspeakable. It demonstrates that, before the theoretical debate over the fundamental representability of the Holocaust was even fully under way, first-generation authors were already translating un-narratable trauma into a literary strategy of un-narrating: a strategy of encrypting the Holocaust into the form and structure of their texts. The implications of treating these writers as a set, and their body of work as a hitherto unacknowledged category of Holocaust fiction, go well beyond drawing attention to a number of important but critically neglected authors. This study frames the analysis of first-generation narrative strategies in the broader debate on the ethics and aesthetics of Holocaust writing. In revealing how certain kinds of testimony have been privileged above others in international Holocaust studies, it raises questions of a more general nature concerning canon formation and our theoretical responses to the Holocaust. In considering foremost among these responses the theory of deconstruction and trauma theory, it finally invites a re-examination of the relationship between the (post-)modern and trauma.']
### GND ID:
['gnd:105858460X', 'gnd:4050479-7', 'gnd:4113292-0', 'gnd:4122228-3', 'gnd:4373760-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A794321771']
### GND class:
['Gwyer, Kirstin', 'Roman', 'Deutsch', 'Judenvernichtung (Motiv)', 'Schreiben nach Auschwitz']
<|eot_id|> |
3A79436070X.jsonld | ['Investigating the feasibility of accelerated drug release testing for intravaginal rings'] | [['Wirkstofffreisetzung, beschleunigte Freisetzungstests, Vaginale Ringe, Diffusion, Qualitätskontrolle, accelerated drug release testing, vaginal rings, diffusion, quality control', 'Accelerated drug release tests are essential for quality control (QC) of long acting (non-oral) controlled release formulations. Real-time release experiments are usually required for product development, to understand the mechanism of release and to establish a correlation with in vivo release. Ideally, the accelerated test should maintain the biorelevant aspect of the in vitro method and the mechanism of release should not change under accelerated test conditions. At the same time adequate discriminatory ability is a prerequisite as the accelerated test should be able to discriminate between batches with respect to manufacturing variables that can impact on bioavailability. The objective of this thesis was to develop accelerated drug release tests for intravaginal rings (IVRs) and to gain a mechanistic understanding of the principles that facilitate in vitro drug release under accelerated test conditions. A detailed evaluation of the in vitro release characteristics of the formulations under real-time test conditions was considered as a prerequisite for developing predictive accelerated tests. Two formulations were subject of this study, in which the mechanism of release is primarily governed by drug diffusion. One formulation was the commercially available Nuvaring®, a combined hormonal contraceptive IVR that releases etonogestrel and ethinylestradiol with a constant rate over a duration of 3 weeks. The second formulation was a prototype of an investigational IVR that is ...']] | ['gnd:4012277-3', 'gnd:4047968-7', 'gnd:4070794-5', 'gnd:4187312-9', 'gnd:4190018-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79436070X'] | ['Diffusion', 'Qualitätskontrolle', 'Empfängnisverhütung', 'Vaginales Arzneimittel', 'Wirkstofffreisetzung'] | Document
### Title: ['Investigating the feasibility of accelerated drug release testing for intravaginal rings']
### Abstract:
[['Wirkstofffreisetzung, beschleunigte Freisetzungstests, Vaginale Ringe, Diffusion, Qualitätskontrolle, accelerated drug release testing, vaginal rings, diffusion, quality control', 'Accelerated drug release tests are essential for quality control (QC) of long acting (non-oral) controlled release formulations. Real-time release experiments are usually required for product development, to understand the mechanism of release and to establish a correlation with in vivo release. Ideally, the accelerated test should maintain the biorelevant aspect of the in vitro method and the mechanism of release should not change under accelerated test conditions. At the same time adequate discriminatory ability is a prerequisite as the accelerated test should be able to discriminate between batches with respect to manufacturing variables that can impact on bioavailability. The objective of this thesis was to develop accelerated drug release tests for intravaginal rings (IVRs) and to gain a mechanistic understanding of the principles that facilitate in vitro drug release under accelerated test conditions. A detailed evaluation of the in vitro release characteristics of the formulations under real-time test conditions was considered as a prerequisite for developing predictive accelerated tests. Two formulations were subject of this study, in which the mechanism of release is primarily governed by drug diffusion. One formulation was the commercially available Nuvaring®, a combined hormonal contraceptive IVR that releases etonogestrel and ethinylestradiol with a constant rate over a duration of 3 weeks. The second formulation was a prototype of an investigational IVR that is ...']]
### GND ID:
['gnd:4012277-3', 'gnd:4047968-7', 'gnd:4070794-5', 'gnd:4187312-9', 'gnd:4190018-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79436070X']
### GND class:
['Diffusion', 'Qualitätskontrolle', 'Empfängnisverhütung', 'Vaginales Arzneimittel', 'Wirkstofffreisetzung']
<|eot_id|> |
3A795297599.jsonld | ['Studien zum synthetischen Zugang zu Ripostatinen und deren Analoga'] | ['RNA-Polymerase-Inhibitor, Difluor-Ripostatin, Ringschlussmetathese, Carboaluminierung, Stille-Kreuzkupplung, Reformatsky-Aldolreaktion. - Difluororipostatin, ring closing metathesis, carboalumination, Stille cross-coupling, Reformatsky aldol reaction'] | ['gnd:1033635499', 'gnd:4168683-4', 'gnd:4324196-7', 'gnd:4412308-5', 'gnd:4734468-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A795297599'] | ['Kreuzkupplungsreaktion', 'Makrolide', 'Aldolreaktion', 'Totalsynthese', 'Ringschlussmetathese'] | Document
### Title: ['Studien zum synthetischen Zugang zu Ripostatinen und deren Analoga']
### Abstract:
['RNA-Polymerase-Inhibitor, Difluor-Ripostatin, Ringschlussmetathese, Carboaluminierung, Stille-Kreuzkupplung, Reformatsky-Aldolreaktion. - Difluororipostatin, ring closing metathesis, carboalumination, Stille cross-coupling, Reformatsky aldol reaction']
### GND ID:
['gnd:1033635499', 'gnd:4168683-4', 'gnd:4324196-7', 'gnd:4412308-5', 'gnd:4734468-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A795297599']
### GND class:
['Kreuzkupplungsreaktion', 'Makrolide', 'Aldolreaktion', 'Totalsynthese', 'Ringschlussmetathese']
<|eot_id|> |
3A795491425.jsonld | ['Genealogy of the tragic : Greek tragedy and German philosophy'] | ['Why did Greek tragedy and "the tragic" come to be seen as essential to conceptions of modernity? And how has this belief affected modern understandings of Greek drama? In Genealogy of the Tragic, Joshua Billings answers these and related questions by tracing the emergence of the modern theory of the tragic, which was first developed around 1800 by thinkers associated with German Idealism. The book argues that the idea of the tragic arose in response to a new consciousness of history in the late eighteenth century, which spurred theorists to see Greek tragedy as both a unique, historically remote form and a timeless literary genre full of meaning for the present. The book offers a new interpretation of the theories of Schiller, Schelling, Hegel, Hölderlin, and others, as mediations between these historicizing and universalizing impulses, and shows the roots of their approaches in earlier discussions of Greek tragedy in Germany, France, and England. By examining eighteenth-century readings of tragedy and the interactions between idealist thinkers in detail, Genealogy of the Tragic offers the most comprehensive historical account of the tragic to date, as well as the fullest explanation of why and how the idea was used to make sense of modernity. The book argues that idealist theories remain fundamental to contemporary interpretations of Greek tragedy, and calls for a renewed engagement with philosophical questions in criticism of tragedy.'] | ['gnd:102637622X', 'gnd:4011882-4', 'gnd:4026468-3', 'gnd:4045791-6', 'gnd:4049716-1', 'gnd:4060591-7', 'gnd:4113791-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A795491425'] | ['Billings, Joshua', 'Deutschland', 'Idealismus', 'Philosophie', 'Rezeption', 'Tragödie', 'Griechisch'] | Document
### Title: ['Genealogy of the tragic : Greek tragedy and German philosophy']
### Abstract:
['Why did Greek tragedy and "the tragic" come to be seen as essential to conceptions of modernity? And how has this belief affected modern understandings of Greek drama? In Genealogy of the Tragic, Joshua Billings answers these and related questions by tracing the emergence of the modern theory of the tragic, which was first developed around 1800 by thinkers associated with German Idealism. The book argues that the idea of the tragic arose in response to a new consciousness of history in the late eighteenth century, which spurred theorists to see Greek tragedy as both a unique, historically remote form and a timeless literary genre full of meaning for the present. The book offers a new interpretation of the theories of Schiller, Schelling, Hegel, Hölderlin, and others, as mediations between these historicizing and universalizing impulses, and shows the roots of their approaches in earlier discussions of Greek tragedy in Germany, France, and England. By examining eighteenth-century readings of tragedy and the interactions between idealist thinkers in detail, Genealogy of the Tragic offers the most comprehensive historical account of the tragic to date, as well as the fullest explanation of why and how the idea was used to make sense of modernity. The book argues that idealist theories remain fundamental to contemporary interpretations of Greek tragedy, and calls for a renewed engagement with philosophical questions in criticism of tragedy.']
### GND ID:
['gnd:102637622X', 'gnd:4011882-4', 'gnd:4026468-3', 'gnd:4045791-6', 'gnd:4049716-1', 'gnd:4060591-7', 'gnd:4113791-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A795491425']
### GND class:
['Billings, Joshua', 'Deutschland', 'Idealismus', 'Philosophie', 'Rezeption', 'Tragödie', 'Griechisch']
<|eot_id|> |
3A796308845.jsonld | ['Die Eisrandtäler im Karakorum : Verbreitung, Genese und Morphodynamik des lateroglazialen Sedimentformenschatzes'] | [['The research study provides a contribution to the geomorphological survey of the lateroglacial landform assemblage along subtropical high mountain glaciers in the Karakoram (72°-79°E; 35°-36°N). The ice-marginal valleys and their lateroglacial landform associations were investigated systematically as a distinct sedimentation environment along 43 glaciers in regard to their distribution, evolution and morphodynamics. The vertical distribution of the present lateroglacial sediments ranges between an altitude of approx. 2350 m and 5200 m. Up to now, especially kame terraces and lateral moraine...', 'Die vorliegende Forschungsarbeit liefert einen Beitrag zur geomorphologischen Erfassung des lateroglazialen Formenschatzes entlang subtropischer Gletscher im Karakorum (72°-79°E; 35°-36°N). Die Eisrandtäler (Ufertäler) und ihr lateroglazialer Sedimentformenschatz wurden erstmals als ausgesonderter Sedimentationsraum an 43 Gletschern hinsichtlich ihrer räumlichen Verbreitung, Genese und Morphodynamik systematisch untersucht. Bislang waren für den eismarginalen Bereich insbesondere Kameterrassen im Sinne von glazifluvialen Ablagerungsformen sowie Ufermoränenkomplexe im geomorphologischen Inve...']] | ['gnd:1024475557', 'gnd:1041847343', 'gnd:123748674', 'gnd:138868751', 'gnd:138869677', 'gnd:138870756', 'gnd:4073227-7', 'gnd:4184374-5', 'gnd:4415032-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A796308845'] | ['Cyffka, Bernd', 'Iturrizaga, Lasafam', 'Ehlers, Jürgen', 'Baume, Otfried', 'Kuhle, Matthias', 'Schröder, Hilmar', 'Karakorum', 'Tal', 'Eisrand'] | Document
### Title: ['Die Eisrandtäler im Karakorum : Verbreitung, Genese und Morphodynamik des lateroglazialen Sedimentformenschatzes']
### Abstract:
[['The research study provides a contribution to the geomorphological survey of the lateroglacial landform assemblage along subtropical high mountain glaciers in the Karakoram (72°-79°E; 35°-36°N). The ice-marginal valleys and their lateroglacial landform associations were investigated systematically as a distinct sedimentation environment along 43 glaciers in regard to their distribution, evolution and morphodynamics. The vertical distribution of the present lateroglacial sediments ranges between an altitude of approx. 2350 m and 5200 m. Up to now, especially kame terraces and lateral moraine...', 'Die vorliegende Forschungsarbeit liefert einen Beitrag zur geomorphologischen Erfassung des lateroglazialen Formenschatzes entlang subtropischer Gletscher im Karakorum (72°-79°E; 35°-36°N). Die Eisrandtäler (Ufertäler) und ihr lateroglazialer Sedimentformenschatz wurden erstmals als ausgesonderter Sedimentationsraum an 43 Gletschern hinsichtlich ihrer räumlichen Verbreitung, Genese und Morphodynamik systematisch untersucht. Bislang waren für den eismarginalen Bereich insbesondere Kameterrassen im Sinne von glazifluvialen Ablagerungsformen sowie Ufermoränenkomplexe im geomorphologischen Inve...']]
### GND ID:
['gnd:1024475557', 'gnd:1041847343', 'gnd:123748674', 'gnd:138868751', 'gnd:138869677', 'gnd:138870756', 'gnd:4073227-7', 'gnd:4184374-5', 'gnd:4415032-5', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A796308845']
### GND class:
['Cyffka, Bernd', 'Iturrizaga, Lasafam', 'Ehlers, Jürgen', 'Baume, Otfried', 'Kuhle, Matthias', 'Schröder, Hilmar', 'Karakorum', 'Tal', 'Eisrand']
<|eot_id|> |
3A796784647.jsonld | ['Multifunktionalität von Niederwäldern in Rheinland-Pfalz : Aspekte des Naturschutzes und des Tourismus'] | [['Zusammenfassung: According to estimates, there are approximately 160 000 ha of forest in Rheinland-Pfalz the origins of which can be traced back to traditional coppice management. Up until the transition from the 19th to the 20th century, coppice was a widespread form of land use in central European broadleaf forests and represented a considerable potential source of wood. These forests were customarily managed in short rotations (usually a maximum of 40 years). Today, however, the majority these stands are now between 60 and 90 years old as, due to a lack of profitability since the postwar period, they have not been coppiced in the intervening years and have outgrown. As a consequence of the recent increase in the demand for woodfuel, coppice management has become an attractive option once more as a means to produce wood for energy use. Coppice forests are also attributed considerable nature conservation value and a high cultural significance. A resumption of coppice management along traditional lines today is largely inconceivable, however. For this reason, it was deemed necessary to collate new findings pertaining to a modern form of coppice management practised in the context of current forest policy, economic aims and ecological objectives as well as in view of technological advances made in timber harvesting. To this end, numerous studies were undertaken as part of the practice-oriented research project ‘Schutz und Nutzung: Ein Raum-Zeit-Konzept für die multifunktionale Entwicklung der Stockausschlagwälder in Rheinland-Pfalz’ [Protection and use: A space and time concept for the multifunctional development of coppice forests in Rheinland-Pfalz]. The project results served to clarify the political, economic and silvicultural framework conditions for modern coppice management, and its role in nature protection and its potential to contribute to regional tourism were assessed. Core elements of the study presented here are the nature conservation and tourism aspects of coppice management', 'Zusammenfassung: In Rheinland-Pfalz befinden sich nach Schätzungen etwa 160.000 ha Stockausschlagwälder, die in ihrer Entstehung auf die traditionelle Niederwaldbewirtschaftung zurückzuführen sind. Die Niederwaldwirtschaft war bis zum Übergang vom 19. zum 20. Jh. in Mitteleuropa eine weit verbreitete Nutzungsform des Laubwaldes und bot dabei ein bedeutendes Holzpotenzial. Herkömmlich wurden die Niederwälder in einer kurzen Umtriebszeit (i.d.R. max. 40 Jahre) bewirtschaftet, sind allerdings mittlerweile schwerpunktmäßig zwischen 60 und 90 Jahre alt, da sie aufgrund mangelnder Rentabilität seit den Nachkriegszeiten nicht mehr „auf den Stock gesetzt“ wurden und folglich durchgewachsen sind. Im Zuge der in jüngster Vergangenheit verstärkten Nachfrage nach Energieholz erfährt die Niederwaldbewirtschaftung mit dem Ziel der Brennholzerzeugung wieder mehr Interesse. Zudem kommen den Niederwäldern eine erhebliche naturschutzfachliche sowie eine hohe landeskulturelle Bedeutung zu. Eine Wiederaufnahme der Niederwaldwirtschaft durch traditionelle Nutzungsweise ist allerdings nicht mehr vorstellbar, weshalb es sich als nötig erwies, neue Erkenntnisse unter Berücksichtigung der aktuellen forstpolitischen, -ökonomischen und -ökologischen Ziele sowie technischer Fortschritte in den Holzernteverfahren zu einer zeitgemäßen Niederwaldnutzung zu sammeln. Die vorliegende Arbeit entstand im Rahmen des praxisorientierten Forschungsprojektes "Schutz und Nutzung: Ein Raum-Zeit-Konzept für die multifunktionale Entwicklung der Stockausschlagwälder in Rheinland-Pfalz". Als Ergebnis des Projektes wurden die politischen, wirtschaftlichen und waldbaulichen Rahmenbedingungen einer modernen Niederwaldbewirtschaftung aufgeklärt sowie ihre Rolle im Naturschutz und deren touristische Nutzugsmöglichkeit auf Landesebene überprüft. Im Mittelpunkt der vorliegenden Arbeit stehen die naturschutzfachlichen und touristischen Aspekte der Niederwaldwirtschaft']] | ['gnd:1058227432', 'gnd:4018406-7', 'gnd:4049795-1', 'gnd:4115348-0', 'gnd:4171869-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A796784647'] | ['Helfrich-Hau, Tímea', 'Tourismus', 'Rheinland-Pfalz', 'Naturschutz', 'Niederwald'] | Document
### Title: ['Multifunktionalität von Niederwäldern in Rheinland-Pfalz : Aspekte des Naturschutzes und des Tourismus']
### Abstract:
[['Zusammenfassung: According to estimates, there are approximately 160 000 ha of forest in Rheinland-Pfalz the origins of which can be traced back to traditional coppice management. Up until the transition from the 19th to the 20th century, coppice was a widespread form of land use in central European broadleaf forests and represented a considerable potential source of wood. These forests were customarily managed in short rotations (usually a maximum of 40 years). Today, however, the majority these stands are now between 60 and 90 years old as, due to a lack of profitability since the postwar period, they have not been coppiced in the intervening years and have outgrown. As a consequence of the recent increase in the demand for woodfuel, coppice management has become an attractive option once more as a means to produce wood for energy use. Coppice forests are also attributed considerable nature conservation value and a high cultural significance. A resumption of coppice management along traditional lines today is largely inconceivable, however. For this reason, it was deemed necessary to collate new findings pertaining to a modern form of coppice management practised in the context of current forest policy, economic aims and ecological objectives as well as in view of technological advances made in timber harvesting. To this end, numerous studies were undertaken as part of the practice-oriented research project ‘Schutz und Nutzung: Ein Raum-Zeit-Konzept für die multifunktionale Entwicklung der Stockausschlagwälder in Rheinland-Pfalz’ [Protection and use: A space and time concept for the multifunctional development of coppice forests in Rheinland-Pfalz]. The project results served to clarify the political, economic and silvicultural framework conditions for modern coppice management, and its role in nature protection and its potential to contribute to regional tourism were assessed. Core elements of the study presented here are the nature conservation and tourism aspects of coppice management', 'Zusammenfassung: In Rheinland-Pfalz befinden sich nach Schätzungen etwa 160.000 ha Stockausschlagwälder, die in ihrer Entstehung auf die traditionelle Niederwaldbewirtschaftung zurückzuführen sind. Die Niederwaldwirtschaft war bis zum Übergang vom 19. zum 20. Jh. in Mitteleuropa eine weit verbreitete Nutzungsform des Laubwaldes und bot dabei ein bedeutendes Holzpotenzial. Herkömmlich wurden die Niederwälder in einer kurzen Umtriebszeit (i.d.R. max. 40 Jahre) bewirtschaftet, sind allerdings mittlerweile schwerpunktmäßig zwischen 60 und 90 Jahre alt, da sie aufgrund mangelnder Rentabilität seit den Nachkriegszeiten nicht mehr „auf den Stock gesetzt“ wurden und folglich durchgewachsen sind. Im Zuge der in jüngster Vergangenheit verstärkten Nachfrage nach Energieholz erfährt die Niederwaldbewirtschaftung mit dem Ziel der Brennholzerzeugung wieder mehr Interesse. Zudem kommen den Niederwäldern eine erhebliche naturschutzfachliche sowie eine hohe landeskulturelle Bedeutung zu. Eine Wiederaufnahme der Niederwaldwirtschaft durch traditionelle Nutzungsweise ist allerdings nicht mehr vorstellbar, weshalb es sich als nötig erwies, neue Erkenntnisse unter Berücksichtigung der aktuellen forstpolitischen, -ökonomischen und -ökologischen Ziele sowie technischer Fortschritte in den Holzernteverfahren zu einer zeitgemäßen Niederwaldnutzung zu sammeln. Die vorliegende Arbeit entstand im Rahmen des praxisorientierten Forschungsprojektes "Schutz und Nutzung: Ein Raum-Zeit-Konzept für die multifunktionale Entwicklung der Stockausschlagwälder in Rheinland-Pfalz". Als Ergebnis des Projektes wurden die politischen, wirtschaftlichen und waldbaulichen Rahmenbedingungen einer modernen Niederwaldbewirtschaftung aufgeklärt sowie ihre Rolle im Naturschutz und deren touristische Nutzugsmöglichkeit auf Landesebene überprüft. Im Mittelpunkt der vorliegenden Arbeit stehen die naturschutzfachlichen und touristischen Aspekte der Niederwaldwirtschaft']]
### GND ID:
['gnd:1058227432', 'gnd:4018406-7', 'gnd:4049795-1', 'gnd:4115348-0', 'gnd:4171869-0', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A796784647']
### GND class:
['Helfrich-Hau, Tímea', 'Tourismus', 'Rheinland-Pfalz', 'Naturschutz', 'Niederwald']
<|eot_id|> |
3A797378987.jsonld | ['Development of biomechatronic devices for measurement of wrenches occurring in animal and human prehension'] | ['Biomechatronik und speziell Biosensoren unterstützen auf der Grundlage biologischer Inspiration das Entstehen neuer Anwendungen in der ganzen Spanne vom Fahrzeugbau bis zur Bio\xadRobotik. Dabei werden Mechatronik, technologisches Wissen, Bionik und Biologie miteinander kombiniert. “There is a market trend towards the use of intelligent sensors. In the past the main reasons for this have been increased measurement accuracy, programmability, decreased inventory cost from the larger turndown available, and a decreased maintenance cost for self\xad diagnostics.” (Expertise,1997).'] | ['gnd:1058881086', 'gnd:120775603', 'gnd:130008338', 'gnd:4006888-2', 'gnd:4017975-8', 'gnd:4158131-3', 'gnd:4165452-3', 'gnd:4238812-0', 'gnd:4257775-5', 'gnd:4307964-7', 'gnd:4571071-5', 'gnd:4798356-5', 'gnd:7635051-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797378987'] | ['Jiménez López, Omar Eduardo', 'Fröhlich, Thomas', 'Witte, Hartmut', 'Bionik', 'Fortbewegung', 'Greifen', 'Kraftsensor', 'Mechatronik', 'Multisensor', 'Sensorsystem', 'Kletterroboter', 'Kontaktmechanik', 'Universitätsverlag Ilmenau'] | Document
### Title: ['Development of biomechatronic devices for measurement of wrenches occurring in animal and human prehension']
### Abstract:
['Biomechatronik und speziell Biosensoren unterstützen auf der Grundlage biologischer Inspiration das Entstehen neuer Anwendungen in der ganzen Spanne vom Fahrzeugbau bis zur Bio\xadRobotik. Dabei werden Mechatronik, technologisches Wissen, Bionik und Biologie miteinander kombiniert. “There is a market trend towards the use of intelligent sensors. In the past the main reasons for this have been increased measurement accuracy, programmability, decreased inventory cost from the larger turndown available, and a decreased maintenance cost for self\xad diagnostics.” (Expertise,1997).']
### GND ID:
['gnd:1058881086', 'gnd:120775603', 'gnd:130008338', 'gnd:4006888-2', 'gnd:4017975-8', 'gnd:4158131-3', 'gnd:4165452-3', 'gnd:4238812-0', 'gnd:4257775-5', 'gnd:4307964-7', 'gnd:4571071-5', 'gnd:4798356-5', 'gnd:7635051-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797378987']
### GND class:
['Jiménez López, Omar Eduardo', 'Fröhlich, Thomas', 'Witte, Hartmut', 'Bionik', 'Fortbewegung', 'Greifen', 'Kraftsensor', 'Mechatronik', 'Multisensor', 'Sensorsystem', 'Kletterroboter', 'Kontaktmechanik', 'Universitätsverlag Ilmenau']
<|eot_id|> |
3A797480269.jsonld | ['Die Implementierung des Kleingruppenprojektmodells und der PROGRESS-Methode : eine vergleichende Evaluationsstudie; work together in ... PROGRESS'] | [['The study examines the effectiveness of two Fortbildungsmodi - School-based Teacher Training (SCHILF) and Regional Educators. She juxtaposes the two educational concepts and looks for the differences in the transfer success of the training object. Under the use of qualitative research tools can be shown that School-based Teacher Training and Regional Educators only marginally differ in effectiveness from one another and the training mode for the transfer success is subordinated.', 'Die Studie untersucht die Wirksamkeit zweier Fortbildungsmodi – Schulinterne Lehrerfortbildung (SCHILF) und Regionale Lehrerfortbildung. Dabei stellt sie die beiden Fortbildungskonzepte gegenüber und sucht nach den Unterschieden im Transfererfolg des Fortbildungsgegenstandes. Unter dem Einsatz qualitativer Forschungswerkzeuge kann gezeigt werden, dass sich Schulinterne Lehrerfortbildung und Regionale Lehrerfortbildung nur marginal in der Wirksamkeit voneinander unterscheiden und der Fortbildungsmodus für den Transfererfolg nachrangig ist.']] | ['gnd:4035096-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797480269'] | ['Lehrerfortbildung'] | Document
### Title: ['Die Implementierung des Kleingruppenprojektmodells und der PROGRESS-Methode : eine vergleichende Evaluationsstudie; work together in ... PROGRESS']
### Abstract:
[['The study examines the effectiveness of two Fortbildungsmodi - School-based Teacher Training (SCHILF) and Regional Educators. She juxtaposes the two educational concepts and looks for the differences in the transfer success of the training object. Under the use of qualitative research tools can be shown that School-based Teacher Training and Regional Educators only marginally differ in effectiveness from one another and the training mode for the transfer success is subordinated.', 'Die Studie untersucht die Wirksamkeit zweier Fortbildungsmodi – Schulinterne Lehrerfortbildung (SCHILF) und Regionale Lehrerfortbildung. Dabei stellt sie die beiden Fortbildungskonzepte gegenüber und sucht nach den Unterschieden im Transfererfolg des Fortbildungsgegenstandes. Unter dem Einsatz qualitativer Forschungswerkzeuge kann gezeigt werden, dass sich Schulinterne Lehrerfortbildung und Regionale Lehrerfortbildung nur marginal in der Wirksamkeit voneinander unterscheiden und der Fortbildungsmodus für den Transfererfolg nachrangig ist.']]
### GND ID:
['gnd:4035096-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797480269']
### GND class:
['Lehrerfortbildung']
<|eot_id|> |
3A797480277.jsonld | ['Die Entwicklung der Auflösung der Aufmerksamkeit'] | [['The ability to select relevant information from the environment is limited by the resolution of attention – i.e., by the minimum size of the region that can be selected by attention. Contrary to many other aspects of attention, the development of this limit has not been investigated in children so far. The aim of this dissertation is to investigate both the development of attentional resolution during school age and the mechanisms underlying this development. We addressed this question in two behavioral experiments and one functional magnetic resonance imaging (fMRI) experiment. In those experiments, subjects of different age groups performed an object tracking task with varying distances between target(s) and distractors. In experiment 1, absolute thresholds – corresponding to the resolution of attention – were determined for 7-, 9- and 11-year-old children, 13-year-old adolescents and an adult sample. A comparison of the thresholds revealed that the resolution of attention develops markedly between childhood and adulthood. Experiment 2 tested the hypotheses that this development can be attributed to an age-related increase in processing resources by varying the number of targets in addition to target-distractor distance. Increasing the number of targets lead to an increase in the absolute threshold across all age groups. However, this increase was especially pronounced in those age groups that had been characterized by a low resolution of attention in Experiment 1. This indicates that the lower attentional resolution of the younger age groups may be related to a lack of an adequate amount of processing resources which restrains them from constricting the focus of attention in an adult-like manner. In Experiment 3, fMRI was performed in children aged 7 years, 11 years, and in young adults to investigate the neural mechanisms underlying the resolution of attention. Increasing the required resolution of attention led to activation increases in fronto-insular cortex, medial frontal cortex including anterior cingulate cortex (ACC) and supplementary motor area, and superior colliculi and thalamus. This circuitry was recruited by all age groups, but ACC showed an age-related activation reduction. Moreover, several non-task-specific areas showed additional activation in the 7-year-olds and decreased activation in the 11-year-olds as compared to the adult sample. Our results suggest that age-related improvements in the resolution of attention are characterized by an increased use of more functionally specialized brain regions during the course of development. In sum, the present results link the marked development of the resolution of attention to an age-related increase in processing resources. On a neurophysiological level, our findings highlight a role of the saliency network in the context of the resolution of attention. From a developmental perspective, the present results establish that children make use of these circuits from an early age. At the same time, however, children show an increasingly specialized use of these brain regions possibly resulting in the increase in processing resources observed at the behavioral level.', 'Das Ziel der vorliegenden Untersuchung bestand darin, die Entwicklung der Auflösung der Aufmerksamkeit im Kindes- und frühen Jugendalter zu charakterisieren und die der Entwicklung zugrunde liegenden Mechanismen zu untersuchen. Zur Untersuchung dieser Fragestellung wurde das Object-Tracking-Paradigma in zwei Verhaltensexperimenten und einem fMRT-Experiment bei Kindern unterschiedlicher Altersgruppen und bei Erwachsenen verwendet. In der ersten Studie wurden sieben-, neun-, elf- und dreizehnjährigen Kindern sowie Erwachsenen das Object-Tracking-Paradigma mit variierendem Abstand zwischen Zielreiz und Distraktoren dargeboten, um den kritischen Abstand der verschiedenen Altersgruppen bestimmen und den Entwicklungsverlauf des kritischen Abstandes über den beobachteten Altersbereich beschreiben zu können. In diesem Entwicklungsverlauf zeigten sich bedeutsame altersbedingte Veränderungen der Auflösung der Aufmerksamkeit. Der kritische Abstand nahm zwischen 7 und 11 Jahren bedeutend ab, blieb zwischen 11 Jahren und 13 Jahren gleich und sank dann noch einmal bedeutsam zum Erwachsenenalter hin. In einer Kontrollaufgabe konnte gezeigt werden, dass sich die dynamische Sehschärfe im gleichen Alterszeitraum nicht veränderte, woraus geschlossen werden kann, dass die Veränderung der Auflösung der Aufmerksamkeit nicht auf die Entwicklung dieser – der Auflösung der Aufmerksamkeit möglicherweise zugrunde liegenden – visuellen Fähigkeit zurückzuführen ist. In der zweiten Studie wurde in der Object-Tracking-Aufgabe neben dem Abstand zwischen Zielreiz und Distraktoren die Anzahl der Zielreize in zwei Stufen (zwei vs. drei Objekte) variiert. Es zeigte sich hier, dass der kritische Abstand von zwei zu drei Zielreizen über alle Altersgruppen hinweg anstieg. Die Reduktion der pro Zielreiz zur Verfügung stehenden Verarbeitungsressourcen bewirkte somit, dass der Fokus der Aufmerksamkeit weniger eng zusammen gezogen werden konnte. Das Ausmaß des Anstiegs des kritischen Abstandes in den verschiedenen Altersgruppen zeichnete zudem den Entwicklungsverlauf der Auflösung der Aufmerksamkeit in Experiment 1 nach. Das heißt, dass der kritische Abstand von zwei zu drei Objekten bei Kindern stärker als bei Erwachsenen zunahm und innerhalb der Kinderstichproben in den Altersgruppen besonders zunahm, die in Experiment 1 eine geringere Auflösung der Aufmerksamkeit gezeigt hatten. Hieraus lässt sich schließen, dass bei Kindern die Verringerung der pro Objekt zur Verfügung stehenden Verarbeitungsressourcen in besonderem Maße dazu führte, dass sie den Fokus der Aufmerksamkeit weniger eng zusammenziehen konnten. Dies deutet darauf hin, dass die in Experiment 1 beobachtete Entwicklung der Auflösung der Aufmerksamkeit damit im Zusammenhang steht, dass den jüngeren Altersgruppen nicht ausreichend Verarbeitungsressourcen zur Verfügung stehen, um den Aufmerksamkeitsfokus so eng wie Erwachsene zusammenzuziehen. In der dritten Studie wurden die neuronalen Korrelate der Auflösung der Aufmerksamkeit bei sieben- und elfjährigen Kindern und bei Erwachsenen verglichen. Entgegen der Erwartung, dass erhöhte Anforderungen an die Präzision der Selektion mit einer erhöhten Aktivierung der FEF einhergehen würden, führte das Zusammenziehen des Fokus der Aufmerksamkeit zu einem Anstieg der neuronalen Aktivität im Salienznetzwerk aus FIC, ACC und Thalamus. Die Aktivierung dieser Areale wies eine hohe Stabilität zwischen 7 Jahren und dem Erwachsenenalter auf. Gleichzeitig zeigten sich jedoch auch Abweichungen in den Aktivierungsmustern von Kindern und Erwachsenen. Innerhalb des Netzwerkes, das über alle Altersgruppen als Antwort auf erhöhte Anforderungen an die Präzision der Selektion aktiviert wurde, zeigte sich eine altersbedingte Reduktion der Aktivierung im ACC. Daneben wurden zusätzlich entwicklungsbedingte Aktivierungsabweichungen im linken superioren frontalen Gyrus, dem Precuneus, dem posterioren cingulären Gyrus und bilateral im lateralen okzipito-temporalen Kortex sichtbar. Dies deutet darauf hin, dass bei Kindern ein Zusammenziehen des Fokus der Aufmerksamkeit durch Kontrollsignale aus von Erwachsenen abweichenden Arealen geleistet wird. Zusammengenommen deuten die Ergebnisse von Experiment 2 und Experiment 3 darauf hin, dass die Entwicklung der Auflösung der Aufmerksamkeit, die in Experiment 1 für das Schulalter beobachtet werden konnte, auf eine altersbedingte Zunahme der Verarbeitungsressourcen zurückzuführen ist. Auf neuronaler Ebene unterstreichen die vorliegenden Ergebnisse die Bedeutung des Salienznetzwerkes für die Auflösung der Aufmerksamkeit und zeigen, dass dieses Netzwerk ab einem frühen Alter verwendet wird, um die Präzision der Selektion zu erhöhen. Gleichzeitig wird die Verwendung dieses Netzwerkes jedoch mit zunehmendem Alter spezifischer, was möglicherweise dazu führt, dass auf Verhaltensebene eine Zunahme der Verarbeitungsressourcen beobachtet werden kann.']] | ['gnd:4068943-8', 'gnd:4133279-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797480277'] | ['Aufmerksamkeit', 'Kognitive Entwicklung'] | Document
### Title: ['Die Entwicklung der Auflösung der Aufmerksamkeit']
### Abstract:
[['The ability to select relevant information from the environment is limited by the resolution of attention – i.e., by the minimum size of the region that can be selected by attention. Contrary to many other aspects of attention, the development of this limit has not been investigated in children so far. The aim of this dissertation is to investigate both the development of attentional resolution during school age and the mechanisms underlying this development. We addressed this question in two behavioral experiments and one functional magnetic resonance imaging (fMRI) experiment. In those experiments, subjects of different age groups performed an object tracking task with varying distances between target(s) and distractors. In experiment 1, absolute thresholds – corresponding to the resolution of attention – were determined for 7-, 9- and 11-year-old children, 13-year-old adolescents and an adult sample. A comparison of the thresholds revealed that the resolution of attention develops markedly between childhood and adulthood. Experiment 2 tested the hypotheses that this development can be attributed to an age-related increase in processing resources by varying the number of targets in addition to target-distractor distance. Increasing the number of targets lead to an increase in the absolute threshold across all age groups. However, this increase was especially pronounced in those age groups that had been characterized by a low resolution of attention in Experiment 1. This indicates that the lower attentional resolution of the younger age groups may be related to a lack of an adequate amount of processing resources which restrains them from constricting the focus of attention in an adult-like manner. In Experiment 3, fMRI was performed in children aged 7 years, 11 years, and in young adults to investigate the neural mechanisms underlying the resolution of attention. Increasing the required resolution of attention led to activation increases in fronto-insular cortex, medial frontal cortex including anterior cingulate cortex (ACC) and supplementary motor area, and superior colliculi and thalamus. This circuitry was recruited by all age groups, but ACC showed an age-related activation reduction. Moreover, several non-task-specific areas showed additional activation in the 7-year-olds and decreased activation in the 11-year-olds as compared to the adult sample. Our results suggest that age-related improvements in the resolution of attention are characterized by an increased use of more functionally specialized brain regions during the course of development. In sum, the present results link the marked development of the resolution of attention to an age-related increase in processing resources. On a neurophysiological level, our findings highlight a role of the saliency network in the context of the resolution of attention. From a developmental perspective, the present results establish that children make use of these circuits from an early age. At the same time, however, children show an increasingly specialized use of these brain regions possibly resulting in the increase in processing resources observed at the behavioral level.', 'Das Ziel der vorliegenden Untersuchung bestand darin, die Entwicklung der Auflösung der Aufmerksamkeit im Kindes- und frühen Jugendalter zu charakterisieren und die der Entwicklung zugrunde liegenden Mechanismen zu untersuchen. Zur Untersuchung dieser Fragestellung wurde das Object-Tracking-Paradigma in zwei Verhaltensexperimenten und einem fMRT-Experiment bei Kindern unterschiedlicher Altersgruppen und bei Erwachsenen verwendet. In der ersten Studie wurden sieben-, neun-, elf- und dreizehnjährigen Kindern sowie Erwachsenen das Object-Tracking-Paradigma mit variierendem Abstand zwischen Zielreiz und Distraktoren dargeboten, um den kritischen Abstand der verschiedenen Altersgruppen bestimmen und den Entwicklungsverlauf des kritischen Abstandes über den beobachteten Altersbereich beschreiben zu können. In diesem Entwicklungsverlauf zeigten sich bedeutsame altersbedingte Veränderungen der Auflösung der Aufmerksamkeit. Der kritische Abstand nahm zwischen 7 und 11 Jahren bedeutend ab, blieb zwischen 11 Jahren und 13 Jahren gleich und sank dann noch einmal bedeutsam zum Erwachsenenalter hin. In einer Kontrollaufgabe konnte gezeigt werden, dass sich die dynamische Sehschärfe im gleichen Alterszeitraum nicht veränderte, woraus geschlossen werden kann, dass die Veränderung der Auflösung der Aufmerksamkeit nicht auf die Entwicklung dieser – der Auflösung der Aufmerksamkeit möglicherweise zugrunde liegenden – visuellen Fähigkeit zurückzuführen ist. In der zweiten Studie wurde in der Object-Tracking-Aufgabe neben dem Abstand zwischen Zielreiz und Distraktoren die Anzahl der Zielreize in zwei Stufen (zwei vs. drei Objekte) variiert. Es zeigte sich hier, dass der kritische Abstand von zwei zu drei Zielreizen über alle Altersgruppen hinweg anstieg. Die Reduktion der pro Zielreiz zur Verfügung stehenden Verarbeitungsressourcen bewirkte somit, dass der Fokus der Aufmerksamkeit weniger eng zusammen gezogen werden konnte. Das Ausmaß des Anstiegs des kritischen Abstandes in den verschiedenen Altersgruppen zeichnete zudem den Entwicklungsverlauf der Auflösung der Aufmerksamkeit in Experiment 1 nach. Das heißt, dass der kritische Abstand von zwei zu drei Objekten bei Kindern stärker als bei Erwachsenen zunahm und innerhalb der Kinderstichproben in den Altersgruppen besonders zunahm, die in Experiment 1 eine geringere Auflösung der Aufmerksamkeit gezeigt hatten. Hieraus lässt sich schließen, dass bei Kindern die Verringerung der pro Objekt zur Verfügung stehenden Verarbeitungsressourcen in besonderem Maße dazu führte, dass sie den Fokus der Aufmerksamkeit weniger eng zusammenziehen konnten. Dies deutet darauf hin, dass die in Experiment 1 beobachtete Entwicklung der Auflösung der Aufmerksamkeit damit im Zusammenhang steht, dass den jüngeren Altersgruppen nicht ausreichend Verarbeitungsressourcen zur Verfügung stehen, um den Aufmerksamkeitsfokus so eng wie Erwachsene zusammenzuziehen. In der dritten Studie wurden die neuronalen Korrelate der Auflösung der Aufmerksamkeit bei sieben- und elfjährigen Kindern und bei Erwachsenen verglichen. Entgegen der Erwartung, dass erhöhte Anforderungen an die Präzision der Selektion mit einer erhöhten Aktivierung der FEF einhergehen würden, führte das Zusammenziehen des Fokus der Aufmerksamkeit zu einem Anstieg der neuronalen Aktivität im Salienznetzwerk aus FIC, ACC und Thalamus. Die Aktivierung dieser Areale wies eine hohe Stabilität zwischen 7 Jahren und dem Erwachsenenalter auf. Gleichzeitig zeigten sich jedoch auch Abweichungen in den Aktivierungsmustern von Kindern und Erwachsenen. Innerhalb des Netzwerkes, das über alle Altersgruppen als Antwort auf erhöhte Anforderungen an die Präzision der Selektion aktiviert wurde, zeigte sich eine altersbedingte Reduktion der Aktivierung im ACC. Daneben wurden zusätzlich entwicklungsbedingte Aktivierungsabweichungen im linken superioren frontalen Gyrus, dem Precuneus, dem posterioren cingulären Gyrus und bilateral im lateralen okzipito-temporalen Kortex sichtbar. Dies deutet darauf hin, dass bei Kindern ein Zusammenziehen des Fokus der Aufmerksamkeit durch Kontrollsignale aus von Erwachsenen abweichenden Arealen geleistet wird. Zusammengenommen deuten die Ergebnisse von Experiment 2 und Experiment 3 darauf hin, dass die Entwicklung der Auflösung der Aufmerksamkeit, die in Experiment 1 für das Schulalter beobachtet werden konnte, auf eine altersbedingte Zunahme der Verarbeitungsressourcen zurückzuführen ist. Auf neuronaler Ebene unterstreichen die vorliegenden Ergebnisse die Bedeutung des Salienznetzwerkes für die Auflösung der Aufmerksamkeit und zeigen, dass dieses Netzwerk ab einem frühen Alter verwendet wird, um die Präzision der Selektion zu erhöhen. Gleichzeitig wird die Verwendung dieses Netzwerkes jedoch mit zunehmendem Alter spezifischer, was möglicherweise dazu führt, dass auf Verhaltensebene eine Zunahme der Verarbeitungsressourcen beobachtet werden kann.']]
### GND ID:
['gnd:4068943-8', 'gnd:4133279-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A797480277']
### GND class:
['Aufmerksamkeit', 'Kognitive Entwicklung']
<|eot_id|> |
3A798142650.jsonld | ['Untersuchungen zur Tribologie und zum Benetzungsverhalten von Elastomerkompositen'] | ['Elastomerkomposite, Nanomaterialien, Reibkoeffizient, Kontaktwinkel, modifizierte Wilhelmy Methode, Tribometer, Sol-Gel-Technik, Gleitlacke, Graphen. - Elastomer composites, nanomaterials, friction coefficient, contact angle, modified Wilhelmy method, sol-gel technique, sliding lacquer, graphene'] | ['gnd:4005493-7', 'gnd:4014162-7', 'gnd:4060847-5', 'gnd:4181431-9', 'gnd:4227242-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798142650'] | ['Benetzung', 'Elastomer', 'Tribologie', 'Siloxane', 'Polyene'] | Document
### Title: ['Untersuchungen zur Tribologie und zum Benetzungsverhalten von Elastomerkompositen']
### Abstract:
['Elastomerkomposite, Nanomaterialien, Reibkoeffizient, Kontaktwinkel, modifizierte Wilhelmy Methode, Tribometer, Sol-Gel-Technik, Gleitlacke, Graphen. - Elastomer composites, nanomaterials, friction coefficient, contact angle, modified Wilhelmy method, sol-gel technique, sliding lacquer, graphene']
### GND ID:
['gnd:4005493-7', 'gnd:4014162-7', 'gnd:4060847-5', 'gnd:4181431-9', 'gnd:4227242-7', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798142650']
### GND class:
['Benetzung', 'Elastomer', 'Tribologie', 'Siloxane', 'Polyene']
<|eot_id|> |
3A798163747.jsonld | ['The UNESCO MAB Programme in South Africa : current challenges and future options relating to the implementation of biosphere reserves'] | [['Biosphärenreservat, Südafrika, UNESCO, MAB, biosphere reserves, spatial prioritization, conservation planning', 'The UNESCO Man and the Biosphere Programme has been active in South Africa for almost 20 years. The country currently has six designated biosphere reserves with a few sites in various stages of the nomination process. Within the South African context, agencies are using a series of seemingly different instruments to practice landscape-scale management. The UNESCO biosphere reserve concept sometimes finds it difficult to obtain prominence amongst these different landscape initiatives. Biosphere reserves are special sites wherein sustainable development is promoted. For this reason, the biosphere reserve concept has much to offer towards long-term sustainable socialecological land management. In our modern age of population growth, dwindling natural resources and a general disconnectedness of humans from nature due to large scale urbanization, there is an urgent need for innovative ways in which to showcase sustainable living practices. South Africa has limited natural, economic and social resources and therefore needs to prioritize where these resources could best be allocated. This dissertation comprises the history of the MAB Programme in South Africa, as well as a multicase study on five existing biosphere reserves. Results from this study indicated that not all biosphere reserves are equally effective in their implementation of the three functions of biosphere reserves and that all biosphere reserves in South Africa face an uncertain future due to pressing challenges ...']] | ['gnd:1059245337', 'gnd:19164-4', 'gnd:4058393-4', 'gnd:4428082-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798163747'] | ['Pool-Stanvliet, Ruida', 'Unesco Man and the Biosphere Programme', 'Südafrika (Kontinent)', 'Biosphärenreservat'] | Document
### Title: ['The UNESCO MAB Programme in South Africa : current challenges and future options relating to the implementation of biosphere reserves']
### Abstract:
[['Biosphärenreservat, Südafrika, UNESCO, MAB, biosphere reserves, spatial prioritization, conservation planning', 'The UNESCO Man and the Biosphere Programme has been active in South Africa for almost 20 years. The country currently has six designated biosphere reserves with a few sites in various stages of the nomination process. Within the South African context, agencies are using a series of seemingly different instruments to practice landscape-scale management. The UNESCO biosphere reserve concept sometimes finds it difficult to obtain prominence amongst these different landscape initiatives. Biosphere reserves are special sites wherein sustainable development is promoted. For this reason, the biosphere reserve concept has much to offer towards long-term sustainable socialecological land management. In our modern age of population growth, dwindling natural resources and a general disconnectedness of humans from nature due to large scale urbanization, there is an urgent need for innovative ways in which to showcase sustainable living practices. South Africa has limited natural, economic and social resources and therefore needs to prioritize where these resources could best be allocated. This dissertation comprises the history of the MAB Programme in South Africa, as well as a multicase study on five existing biosphere reserves. Results from this study indicated that not all biosphere reserves are equally effective in their implementation of the three functions of biosphere reserves and that all biosphere reserves in South Africa face an uncertain future due to pressing challenges ...']]
### GND ID:
['gnd:1059245337', 'gnd:19164-4', 'gnd:4058393-4', 'gnd:4428082-8', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798163747']
### GND class:
['Pool-Stanvliet, Ruida', 'Unesco Man and the Biosphere Programme', 'Südafrika (Kontinent)', 'Biosphärenreservat']
<|eot_id|> |
3A798308427.jsonld | ['Methoden zur Schaffung von Bewusstsein über persönliche Informationen als notwendige Voraussetzung für den Schutz der Privatsphäre'] | ['Privatsphäre, nutzerfreundlicher Privatsphärenschutz, Bewusstsein, social media, Fotos, Metadaten, mobile Apps, Standortinformationen, Standortverschleierung. - Privacy, usable privacy, awareness, photos, metadata, location information, location obfuscation'] | ['gnd:4011144-1', 'gnd:4123980-5', 'gnd:4639271-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798308427'] | ['Datensicherung', 'Privatsphäre', 'Social Media'] | Document
### Title: ['Methoden zur Schaffung von Bewusstsein über persönliche Informationen als notwendige Voraussetzung für den Schutz der Privatsphäre']
### Abstract:
['Privatsphäre, nutzerfreundlicher Privatsphärenschutz, Bewusstsein, social media, Fotos, Metadaten, mobile Apps, Standortinformationen, Standortverschleierung. - Privacy, usable privacy, awareness, photos, metadata, location information, location obfuscation']
### GND ID:
['gnd:4011144-1', 'gnd:4123980-5', 'gnd:4639271-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798308427']
### GND class:
['Datensicherung', 'Privatsphäre', 'Social Media']
<|eot_id|> |
3A798340487.jsonld | ['Assessing the adoption and impact of organic and fair trade certification of pepper in India'] | ['Adoption, fair trade, impact, organic farming, poverty. - Armut, Auswirkungen, fairer Handel, ökologische Landwirtschaft'] | ['gnd:4020933-7', 'gnd:4123525-3', 'gnd:4145629-4', 'gnd:4224214-9', 'gnd:4360045-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798340487'] | ['Gewürz', 'Kleinbauer', 'Biologischer Landbau', 'Wirkungsanalyse', 'Fairer Handel'] | Document
### Title: ['Assessing the adoption and impact of organic and fair trade certification of pepper in India']
### Abstract:
['Adoption, fair trade, impact, organic farming, poverty. - Armut, Auswirkungen, fairer Handel, ökologische Landwirtschaft']
### GND ID:
['gnd:4020933-7', 'gnd:4123525-3', 'gnd:4145629-4', 'gnd:4224214-9', 'gnd:4360045-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798340487']
### GND class:
['Gewürz', 'Kleinbauer', 'Biologischer Landbau', 'Wirkungsanalyse', 'Fairer Handel']
<|eot_id|> |
3A798384123.jsonld | ['Nicht-instantane Polarisationsdynamik in Dielektrika'] | ['Frequenzabhängige Suszeptibilität, Dispersions-Scan-Verfahren, nichtlineare Antwortfunktion. - Frequency-dependent susceptibility, dispersion-scan, nonlinear response function'] | ['gnd:1254195521', 'gnd:4130722-7', 'gnd:4136925-7', 'gnd:4150202-4', 'gnd:4181398-4', 'gnd:4186583-2', 'gnd:4304582-0', 'gnd:4397956-7', 'gnd:4624080-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798384123'] | ['Hoffmann, Mathias', 'Laserimpuls', 'Dünne Schicht', 'Dispersion (Welle)', 'Siliciumoxide', 'Übergangsmetalloxide', 'Nichtlinearer Prozess', 'Dynamische Suszeptibilität', 'Polarisierte Strahlung'] | Document
### Title: ['Nicht-instantane Polarisationsdynamik in Dielektrika']
### Abstract:
['Frequenzabhängige Suszeptibilität, Dispersions-Scan-Verfahren, nichtlineare Antwortfunktion. - Frequency-dependent susceptibility, dispersion-scan, nonlinear response function']
### GND ID:
['gnd:1254195521', 'gnd:4130722-7', 'gnd:4136925-7', 'gnd:4150202-4', 'gnd:4181398-4', 'gnd:4186583-2', 'gnd:4304582-0', 'gnd:4397956-7', 'gnd:4624080-9', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798384123']
### GND class:
['Hoffmann, Mathias', 'Laserimpuls', 'Dünne Schicht', 'Dispersion (Welle)', 'Siliciumoxide', 'Übergangsmetalloxide', 'Nichtlinearer Prozess', 'Dynamische Suszeptibilität', 'Polarisierte Strahlung']
<|eot_id|> |
3A798389281.jsonld | ['Studien zum synthetischen Zugang zu Ripostatinen und deren Analoga'] | ['RNA-Polymerase-Inhibitor, Difluor-Ripostatin, Ringschlussmetathese, Carboaluminierung, Stille-Kreuzkupplung, Reformatsky-Aldolreaktion. - Difluororipostatin, ring closing metathesis, carboalumination, Stille cross-coupling, Reformatsky aldol reaction'] | ['gnd:1033635499', 'gnd:4168683-4', 'gnd:4324196-7', 'gnd:4412308-5', 'gnd:4734468-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798389281'] | ['Kreuzkupplungsreaktion', 'Makrolide', 'Aldolreaktion', 'Totalsynthese', 'Ringschlussmetathese'] | Document
### Title: ['Studien zum synthetischen Zugang zu Ripostatinen und deren Analoga']
### Abstract:
['RNA-Polymerase-Inhibitor, Difluor-Ripostatin, Ringschlussmetathese, Carboaluminierung, Stille-Kreuzkupplung, Reformatsky-Aldolreaktion. - Difluororipostatin, ring closing metathesis, carboalumination, Stille cross-coupling, Reformatsky aldol reaction']
### GND ID:
['gnd:1033635499', 'gnd:4168683-4', 'gnd:4324196-7', 'gnd:4412308-5', 'gnd:4734468-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798389281']
### GND class:
['Kreuzkupplungsreaktion', 'Makrolide', 'Aldolreaktion', 'Totalsynthese', 'Ringschlussmetathese']
<|eot_id|> |
3A798569492.jsonld | ['Skaz und Unreliable Narration : Entwurf einer neuen Typologie des Erzählers'] | ['"For decades, experts in Slavic studies and English and American studies have engaged in separate discussions on the narratological concepts of skaz and unreliable narration, generally unbeknownst to each other. This study challenges earlier attempts to define these terms and uses close textual analysis to integrate these stylistic and semantic phenomena for the first time into a new and synthetic typology of the narrator." --'] | ['gnd:122750780', 'gnd:4152967-4', 'gnd:4195138-4', 'gnd:4306101-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798569492'] | ['Ohme, Andreas', 'Erzähler', 'Unzuverlässigkeit', 'Skas'] | Document
### Title: ['Skaz und Unreliable Narration : Entwurf einer neuen Typologie des Erzählers']
### Abstract:
['"For decades, experts in Slavic studies and English and American studies have engaged in separate discussions on the narratological concepts of skaz and unreliable narration, generally unbeknownst to each other. This study challenges earlier attempts to define these terms and uses close textual analysis to integrate these stylistic and semantic phenomena for the first time into a new and synthetic typology of the narrator." --']
### GND ID:
['gnd:122750780', 'gnd:4152967-4', 'gnd:4195138-4', 'gnd:4306101-1', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A798569492']
### GND class:
['Ohme, Andreas', 'Erzähler', 'Unzuverlässigkeit', 'Skas']
<|eot_id|> |
3A799177776.jsonld | ['Applications in computational finance with a focus on approximation of financial time series by neurocomputing'] | ['Neural network, financial time series, approximation, forecasting. - Neuronale Netze, Finanzzeitreihen, Prognose'] | ['gnd:173979939', 'gnd:4067486-1', 'gnd:4115601-8', 'gnd:4204791-2', 'gnd:4226127-2', 'gnd:4358095-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799177776'] | ['Spreckelsen, Christian', 'Zeitreihenanalyse', 'Portfoliomanagement', 'Devisenoption', 'Neuronales Netz', 'Prognoseverfahren'] | Document
### Title: ['Applications in computational finance with a focus on approximation of financial time series by neurocomputing']
### Abstract:
['Neural network, financial time series, approximation, forecasting. - Neuronale Netze, Finanzzeitreihen, Prognose']
### GND ID:
['gnd:173979939', 'gnd:4067486-1', 'gnd:4115601-8', 'gnd:4204791-2', 'gnd:4226127-2', 'gnd:4358095-6', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799177776']
### GND class:
['Spreckelsen, Christian', 'Zeitreihenanalyse', 'Portfoliomanagement', 'Devisenoption', 'Neuronales Netz', 'Prognoseverfahren']
<|eot_id|> |
3A799204935.jsonld | ['Vorhersage von intragastralen Nahrungsmitteleffekten : Untersuchungen zur Wirkstofffreisetzung und Magenpassage fester oraler Arzneiformen'] | [['Food effects on oral drug delivery are a central issue in the fields of biopharmacy and clinical pharmacology. Therefore, physiological factors, which may affect drug release from solid oral dosage forms in the fed stomach, have been investigated in detail in the present work. For this purpose, a biorelevant dissolution test device (Fed Stomach Model, FSM) has been developed. The FSM was designed as a flow-through system that allowed the biorelevant simulation of dosage form movement in stomach, intragastric pressures as well as gastric media flow. The functionality and applicability of the FSM was demonstrated using a bi-layer modified release tablet containing diclofenac sodium. The regional characteristics of the stomach in terms of mechanical stresses were taken into account in the form of test programs specific for fundus, antrum and gastric emptying. Furthermore, based on the results of a Magnetic Marker Monitoring study, these test programs were combined in different sequences in three test scenarios. In this manner, different deposition patterns of solid oral dosage forms in the fed stomach could be mimicked. Depending on the test scenario, different drug release rates were observed. The simulation of mild stresses in the fundus led to relatively low release rates. In contrast, the high mechanical stresses representing the physiological conditions in the antrum and during gastric emptying resulted in higher drug release rates. In accordance with gastric physiology, ...', 'Pharmazeutische Technologie, Biopharmazie, Magen, Feste Arzneiform, Wirkstofffreisetzung, Kernspintomographie, Biorelevante Wirkstofffreisetzung, Nahrungsmitteleffekt, Biopharmacy, food effects, biorelevant dissolution, solid oral dosage forms, stomach']] | ['gnd:4006890-0', 'gnd:4034870-2', 'gnd:4036943-2', 'gnd:4045699-7', 'gnd:4120806-7', 'gnd:4154167-4', 'gnd:4190018-2', 'gnd:4190021-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799204935'] | ['Biopharmazie', 'Lebensmittel', 'Magen', 'Pharmazeutische Technologie', 'Kernspintomografie', 'Feste Arzneiform', 'Wirkstofffreisetzung', 'Wirkung'] | Document
### Title: ['Vorhersage von intragastralen Nahrungsmitteleffekten : Untersuchungen zur Wirkstofffreisetzung und Magenpassage fester oraler Arzneiformen']
### Abstract:
[['Food effects on oral drug delivery are a central issue in the fields of biopharmacy and clinical pharmacology. Therefore, physiological factors, which may affect drug release from solid oral dosage forms in the fed stomach, have been investigated in detail in the present work. For this purpose, a biorelevant dissolution test device (Fed Stomach Model, FSM) has been developed. The FSM was designed as a flow-through system that allowed the biorelevant simulation of dosage form movement in stomach, intragastric pressures as well as gastric media flow. The functionality and applicability of the FSM was demonstrated using a bi-layer modified release tablet containing diclofenac sodium. The regional characteristics of the stomach in terms of mechanical stresses were taken into account in the form of test programs specific for fundus, antrum and gastric emptying. Furthermore, based on the results of a Magnetic Marker Monitoring study, these test programs were combined in different sequences in three test scenarios. In this manner, different deposition patterns of solid oral dosage forms in the fed stomach could be mimicked. Depending on the test scenario, different drug release rates were observed. The simulation of mild stresses in the fundus led to relatively low release rates. In contrast, the high mechanical stresses representing the physiological conditions in the antrum and during gastric emptying resulted in higher drug release rates. In accordance with gastric physiology, ...', 'Pharmazeutische Technologie, Biopharmazie, Magen, Feste Arzneiform, Wirkstofffreisetzung, Kernspintomographie, Biorelevante Wirkstofffreisetzung, Nahrungsmitteleffekt, Biopharmacy, food effects, biorelevant dissolution, solid oral dosage forms, stomach']]
### GND ID:
['gnd:4006890-0', 'gnd:4034870-2', 'gnd:4036943-2', 'gnd:4045699-7', 'gnd:4120806-7', 'gnd:4154167-4', 'gnd:4190018-2', 'gnd:4190021-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799204935']
### GND class:
['Biopharmazie', 'Lebensmittel', 'Magen', 'Pharmazeutische Technologie', 'Kernspintomografie', 'Feste Arzneiform', 'Wirkstofffreisetzung', 'Wirkung']
<|eot_id|> |
3A799335193.jsonld | ['Telemonitoring bei Herzinsuffizienzpatienten als Leistung eines Krankenhauses : eine Wirtschaftlichkeitsrechnung aus Sicht der Universitätsmedizin Greifswald'] | [['Hospitals play a major role in research projects on telemonitoring in patients with heart failure. Although the knowledge of its microeconomic consequences present a prerequisite for a sustainable implementation of the service beyond research projects as well as for negotiations on reimbursements, this has not been in the focus of scientific interest so far. It, therefore, is the aim to weigh costs and effects caused by telemonitoring of patients with heart failure from the perspective of a university hospital in a rural area. The interventional costs were determined. Changes in the parameters number of cases, length of hospital stay and number of fused cases due to early rehospitalisation were quantified and monetarily assessed. Differences between intervention and control group from a prospective, randomised and controlled study were taken to quantify the effects. The results of the economic calculation were tested in deterministic sensitivity analyses. Given the current frame conditions and the assumptions made in this calculation, the effects resulting from overseeing patients with heart failure via telemonitoring do not outbalance the costs of the intervention. Although the result appeared to be stable in most of the scenarios tested in the sensitivity analyses, there might be other reasons that should be taken into account when deciding on whether or not to provide this service.', 'Herzinsuffizienz, Telemedizin, Krankenhaus, Wirtschaftlichkeitsrechnung, Ländlicher Raum, Telemonitoring, heart failure, hospital, economic evaluation, rural area']] | ['gnd:16329317-X', 'gnd:4024655-3', 'gnd:4032786-3', 'gnd:4034026-0', 'gnd:4066426-0', 'gnd:4209015-5', 'gnd:4491714-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799335193'] | ['Universitätsmedizin Greifswald', 'Herzinsuffizienz', 'Krankenhaus', 'Ländlicher Raum', 'Wirtschaftlichkeitsrechnung', 'Monitoring', 'Telemedizin'] | Document
### Title: ['Telemonitoring bei Herzinsuffizienzpatienten als Leistung eines Krankenhauses : eine Wirtschaftlichkeitsrechnung aus Sicht der Universitätsmedizin Greifswald']
### Abstract:
[['Hospitals play a major role in research projects on telemonitoring in patients with heart failure. Although the knowledge of its microeconomic consequences present a prerequisite for a sustainable implementation of the service beyond research projects as well as for negotiations on reimbursements, this has not been in the focus of scientific interest so far. It, therefore, is the aim to weigh costs and effects caused by telemonitoring of patients with heart failure from the perspective of a university hospital in a rural area. The interventional costs were determined. Changes in the parameters number of cases, length of hospital stay and number of fused cases due to early rehospitalisation were quantified and monetarily assessed. Differences between intervention and control group from a prospective, randomised and controlled study were taken to quantify the effects. The results of the economic calculation were tested in deterministic sensitivity analyses. Given the current frame conditions and the assumptions made in this calculation, the effects resulting from overseeing patients with heart failure via telemonitoring do not outbalance the costs of the intervention. Although the result appeared to be stable in most of the scenarios tested in the sensitivity analyses, there might be other reasons that should be taken into account when deciding on whether or not to provide this service.', 'Herzinsuffizienz, Telemedizin, Krankenhaus, Wirtschaftlichkeitsrechnung, Ländlicher Raum, Telemonitoring, heart failure, hospital, economic evaluation, rural area']]
### GND ID:
['gnd:16329317-X', 'gnd:4024655-3', 'gnd:4032786-3', 'gnd:4034026-0', 'gnd:4066426-0', 'gnd:4209015-5', 'gnd:4491714-4', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799335193']
### GND class:
['Universitätsmedizin Greifswald', 'Herzinsuffizienz', 'Krankenhaus', 'Ländlicher Raum', 'Wirtschaftlichkeitsrechnung', 'Monitoring', 'Telemedizin']
<|eot_id|> |
3A799548804.jsonld | ['Afro-European trade in the Atlantic world : the western Slave Coast, c.1550 - c.1885'] | ['Introduction -- The regional setting -- The Atlantic connection: Little Popo & the rise of Afro-European trade, c. 1600-1702 -- The era of the warrior kings: 1702 to 1772 -- The era of the traders: 1772 to c.1807 -- Disintigration & reconstitution: political developments, 1820s to 1870s -- From slaves to palm oil: Afro-European trade, c.1807 to 1870s -- Epilogue: the colonial partition & its consequences, 1870s to c.1900'] | ['gnd:120998734', 'gnd:4015701-5', 'gnd:4079203-1', 'gnd:4198287-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799548804'] | ['Strickrodt, Silke', 'Europa', 'Westafrika', 'Sklavenhandel'] | Document
### Title: ['Afro-European trade in the Atlantic world : the western Slave Coast, c.1550 - c.1885']
### Abstract:
['Introduction -- The regional setting -- The Atlantic connection: Little Popo & the rise of Afro-European trade, c. 1600-1702 -- The era of the warrior kings: 1702 to 1772 -- The era of the traders: 1772 to c.1807 -- Disintigration & reconstitution: political developments, 1820s to 1870s -- From slaves to palm oil: Afro-European trade, c.1807 to 1870s -- Epilogue: the colonial partition & its consequences, 1870s to c.1900']
### GND ID:
['gnd:120998734', 'gnd:4015701-5', 'gnd:4079203-1', 'gnd:4198287-3', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A799548804']
### GND class:
['Strickrodt, Silke', 'Europa', 'Westafrika', 'Sklavenhandel']
<|eot_id|> |
3A79964708X.jsonld | ['Essays on social value creation in the not-for-profit sector'] | ['Social entrepreneurship, social value, organizational effectiveness. - Sozialunternehmertum, soziale Wirkung, Effektivität von Organisationen'] | ['gnd:1103833715', 'gnd:4115404-6', 'gnd:4167290-2', 'gnd:4197034-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79964708X'] | ['Kröger, Arne', 'Nonprofit-Bereich', 'Leistungsmessung', 'Erfolgsfaktor'] | Document
### Title: ['Essays on social value creation in the not-for-profit sector']
### Abstract:
['Social entrepreneurship, social value, organizational effectiveness. - Sozialunternehmertum, soziale Wirkung, Effektivität von Organisationen']
### GND ID:
['gnd:1103833715', 'gnd:4115404-6', 'gnd:4167290-2', 'gnd:4197034-2', 'https://www.tib.eu/de/suchen/id/TIBKAT%3A79964708X']
### GND class:
['Kröger, Arne', 'Nonprofit-Bereich', 'Leistungsmessung', 'Erfolgsfaktor']
<|eot_id|> |
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