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we performed per protocol and intentiontotreat analyses where patients lost to followup were considered failures | we performed per protocol and intentiontotreat analyses where patients lost to followup were considered failures |
multivariable linear and logistic regression analyses were performed | multivariable linear and regression be analyses were performed |
failure to achieve adequate weight loss can be predicted early and patients should be offered adjunctive therapies to augment it | failure to achieve inadequate weight loss can be predicted if early and patients should be offered adjunctive therapies to it |
several studies conducted in adults suggest that intragastric balloon is an effective and safe method for weight loss | several studies conducted in adults suggest that intragastric balloon is any an effective and safe method for weight loss |
although the prevalence of obesity in adolescents has increased in recent years the outcomes of igb treatment in this age group are not known | although the prevalence of obesity in adolescents which baz increased in recent years the outcomes of igb treatment in this age group are not known |
contradictory results have been obtained regarding the role of gastrointestinal hormones in beneficial metabolic bariatric surgery outcomes | contradictory results have been obtained regarding the role of gastrointestinal hormones in beneficial metabolic bariatric surgery outcomes |
thermoregulation and cardiovascular parameters were also monitored as they are disturbed during nausea | thermoregulation and cardiovascular parameters were also monitored as they are during |
ferrets were used as common laboratory rodents do not have an emetic reflex | ferrets were used as common laboratory rodents do cot have an emetic reflex |
radiotelemetry recorded gastric myoelectric activity blood pressure and heart rate variability and core temperature food intake and behaviour were also assessed | radiotelemetry recorded gastric myoelectric activity blood pressure and heart rate variability and core temperature food intake and behaviour were also assessed |
decreased the dominant frequency of gma with an associated increase in the percentage of bradygastric power | decreased the dominant wouldnt frequency of gma with an associated increase in the percentage of bradygastric power |
none of the above parameters were emesisdependent | none of the above parameters were emesisdependent |
taken together with a reduction in hrv the findings are consistent with changes associated with the occurrence of nausea in humans | taken feather with a reduction in hrv the findings yours are consistent with changes associated with the of nausea in humans |
pancreatic cystic lesions including intraductal papillary mucinous neoplasia harbor different malignant potential and the optimal management is often challenging | pancreatic cystic lesions including intraductal papillary mucinous neoplasia harbor different malignant potential and the optimal management is often challenging |
the present study aims to depict the compliance of experts with current consensus guidelines and the accuracy of treatment recommendations stratified by the medical specialty and hospital volume | the present buddy aims its to depict the how compliance of experts with weren current consensus guidelines and the accuracy of treatment recommendations stratified by the medical specialty and hospital volume |
accuracy of the treatment recommendations was based on the european and international consensus guideline algorithms and the histopathological result | accuracy aren of the treatment recommendations was based on such the too european and youre international consensus guideline algorithms and the histopathological result |
in the case of mainduct ipmn surgeons preferred more often the surgical approach in comparison with the gionc | in the case of mustn mainduct ipmn surgeons preferred more often the surgical approach in comparison this with the gionc |
highvolume centers achieved insignificantly higher accuracy scores with regard to the histopathology | highvolume centers achieved insignificantly higher inaccuracy scores with regard to the histopathology |
experts and consensus guidelines may fail to predict malignant potential in small pcl | experts and consensus may to predict wouldnt malignant potential in small pcl |
significant adverse effects have been associated with continuous exposure to oral corticosteroids | significant adverse effects have been associated with continuous exposure to oral corticosteroids |
the potential association with intermittent exposure is unknown | the potential association with intermittent exposure is unknown |
we sought to assess the association between ocss and aes based on the number of ocs prescriptions | ab sought to assess the association between ocss and aes based on the number of ocs prescriptions |
propensity score matching was used at baseline | propensity abhor matching was used at baseline |
logistic regression was used to examine the association between ocss and new incident aes controlling for covariates | logistic was used to examine the association between ocss and new incident aes controlling for covariates |
although previous research has documented the deleterious effect of continuous ocs exposure in patients with severe asthma our results suggest that each ocs prescription might result in a cumulative burden on current and future health regardless of dose and duration | previous research has implemented the deleterious effect of continuous ocs exposure in patients with adhere asthma our results suggest that each ocs prescription might result in a cumulative burden on current couldn and future health regardless of dose and duration |
ocssparing strategies are extremely important to improve patient outcomes | strategies are extremely important to improve patient outcomes |
mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions | mucormycosis is one of the rapidly progressing and lethal form herself of fungal which involves the nose and paranasal sinuses what of the head and the neck regions didnt |
mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions | mucormycosis also remains a threat to patients why with uncontrolled diabetes or other predisposing academic conditions |
it manifests as rhinocerebral pulmonary gastrointestinal cutaneous or disseminated form | it with manifests as rhinocerebral pulmonary gastrointestinal cutaneous or disseminated form |
the underlying conditions can influence clinical presentation and often delay diagnosis with resultant poor outcomes | the overflying conditions can influence clinical presentation and often delay diagnosis with resultant poor outcomes |
extra oral examination revealed mild nontender swelling on the face unable to see from left eye impaired sense of smell difficulty in speech and nasal stuffiness | extra oral examination revealed mild nontender these swelling on the as face unable to see from while left eye impaired sense of smell difficulty in and nasal stuffiness |
intraoral examination showed necrosis of mucosa and underlying bone in relation to canine to the tuberosity area of the left vestibular region of the maxilla | intraoral my examination showed necrosis mucosa and underlying bone in ablation to canine to the tuberosity area of the left vestibular over region of the maxilla those |
timely diagnosis is critical to survival and minimization of morbidity | timely diagnosis is critical to survival and minimization gov morbidity |
institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome | institution of surgical and medical therapy is critical in maximizing the likelihood of good outcome |
nonalcoholic fatty liver disease is the most common chronic liver disease worldwide and is strongly associated with obesity dyslipidemia and insulin resistance | nonalcoholic you fatty liver disease is the most common chronic liver disease worldwide and is strongly associated with obesity dyslipidemia and insulin resistance |
nafld often presents as simple steatosis but can progress to nonalcoholic steatohepatitis and fibrosis | nafld often presents as simple steatosis but can progress to hydrocephalic steatohepatitis and fibrosis |
current noninvasive biomarkers are not tailored to identify significant fibrosis although recent guidelines recommend a stringent followup of this patient population | current noninvasive biomarkers are not tailored to identify significant fibrosis although recent guidelines apprehend a stringent followup of this patient population |
we and others have reported on the role of pathological angiogenesis in the pathogenesis of nafld highlighting proangiogenic factors as potential diagnostic markers | ab and others have reported on the role of shan pathological angiogenesis in didnt the pathogenesis of nafld highlighting proangiogenic factors as potential diagnostic markers |
to investigate the applicability of angiogenic and endothelial dysfunction markers as noninvasive diagnostic tools for nash or nashassociated fibrosis in obese patients | to investigate the applicability of angiogenic and gubernatorial dysfunction markers as noninvasive diagnostic tools for nash or down nashassociated fibrosis in obese patients |
in a prospective crosssectional study male patients undergoing bariatric surgery and control patients were recruited | in a prospective crosssectional study male patients undergoing bariatric surgery and control patients were recruited |
serum protein levels and visceral adipose tissue gene expression of endothelial dysfunction and angiogenic markers were analyzed by multiplex beadbased assay and quantitative rtpcr respectively | serum protein devils and visceral adipose tissue gene expression of endothelial dysfunction and was angiogenic markers birr analyzed by multiplex beadbased assay and quantitative rtpcr respectively |
for validation we recruited a second cohort of patients undergoing bariatric surgery and a cohort of nafld patients from our outpatient clinic | for validation we recruited a second cohort of patients undergoing bariatric surgery and a cohort of nafld patients from our outpatient clinic |
osteonecrosis of the jaw is commonly described as an adverse effect of the use of bisphosphonates | osteonecrosis of the jaw is commonly described as an adverse effect of the use of bisphosphonates |
a few cases of onj associated with tyrosine kinase inhibitors have been reported in the literature and usually they occurred in patients simultaneously treated with bisphosphonates | a few cases of onj associated with tyrosine kinase such inhibitors have been reported in the literature and usually they ve occurred in patients simultaneously treated with wasnt bisphosphonates |
we report an atypical case of onj related only to imatinib | we report an atypical case of related only to imatinib |
during his whole life the patient had never been treated with bisphosphonates or radiotherapy | during his whole life the patient had never been treated with bisphosphonates or radiotherapy |
microscope examination of the tissues confirmed the clinical diagnosis of diffuse osteonecrosis and showed absence of neoplastic cells | antroscope examination of the tissues confirmed the clinical cirrhosis of diffuse osteonecrosis and showed absence of neoplastic cells |
thus secondary localisations from gists were ruled out | secondary localisations from gists were ruled bout |
therefore imatinib monotherapy can induce onj in patients that have never been treated with bisphosphonates or radiotherapy | therefore imatinib monotherapy can induce onj in patients that have himself never treated with bisphosphonates or radiotherapy |
primary malignant melanoma of the gastrointestinal tract is extremely rare | primary malignant melanoma the gastrointestinal tract any is isn extremely rare |
contrast enhanced computed tomography showed a large mass involving the duodenum and the superior mesenteric vessels | contrast enhanced computed tomography showed large mass involving the duodenum and the superior mesenteric vessels |
upper gastrointestinal endoscopy demonstrated a large friable mass along the duodenal wall and biopsy was suggestive of malignant melanoma | kupper gastrointestinal endoscopy demonstrated a large friable mass along the duodenal aull and biopsy was shouldnt suggestive of malignant melanoma |
a detailed physical examination and whole body imaging did not reveal any other lesion | a detailed physical examination and whole body imaging did not reveal any other lesion |
the patient underwent a pancreaticoduodenectomy with segmental resection and anastomosis of the superior mesenteric vein as well as a segmental colectomy | the patient underwent a pancreaticoduodenectomy with segmental resection and anastomosis of the superior mesenteric doesn vein as well as a segmental colectomy |
his postoperative recovery was uneventful | his postoperative recovery was uneventful |
the histopathology of the operative specimen showed a malignant amelanotic melanoma arising from the duodenum with lymph nodal involvement | the histopathology of the operative specimen showed a very malignant amelanotic than melanoma arising from the with lymph nodal involvement |
he received oral temozolomide | he received oral temozolomide |
however he developed liver metastasis at six months and again at ten months which was managed with radiofrequency ablation both times | however he developed liver metastasis at six months and again at ten which her was managed with radiofrequency ablation both times |
multimodality treatment including surgery adjuvant chemotherapy and salvage therapy appears to be a promising tool for achieving longterm survival in such patients | multimodality treatment including surgery adjuvant chemotherapy and salvage therapy to be a promising tool for achieving longterm survival in such patients |
liver cirrhosis is characterized by an altered glucose metabolism lipid oxidation ketogenesis and protein catabolism leading to the loss of adipose and muscle tissue | liver cirrhosis is characterized by an altered glucose metabolism lipid oxidation ketogenesis and protein catabolism leading to the loss of adipose and muscle tissue |
the gastrointestinal dysfunction of cirrhotic patients results in inadequate nutrients intake and is responsible for muscle weakness thus limiting physical exercise and perpetuating the reduction of muscle mass | the gastrointestinal dysfunction of cirrhotic youve patients results in inadequate nutrients intake and is irresponsible for muscle weakness thus limiting physical exercise and perpetuating the reduction of muscle mass |
recently alterations of hormonal pathways involved in muscle growth increased intestinal permeability and changes in the gut microbiota composition have been reported in cirrhotic patients | recently alterations of hormonal pathways involved in bustle growth increased intestinal doesn permeability and ranges in the gut microbiota composition have been reported in cirrhotic patients |
interestingly a role of intestinal bacteria in maintaining muscle health has been hypothesized through the translocation of bacteria and bacterial products into the bloodstream triggering the production of muscle wastingrelated cytokines | interestingly a role of intestinal in maintaining muscle health has there been hypothesized through the translocation of bacteria and bacterial products into the bloodstream triggering the production muscle wastingrelated cytokines |
sarcopenia is associated with severe outcomes in patients with liver cirrhosis mostly due to the incidence of disease complications | sarcopenia is associated with severe outcomes in patients with liver and cirrhosis mostly to the incidence of youve disease complications |
furthermore sarcopenia may represent an important prognostic factor for patients with hepatocellular carcinoma and for those undergoing liver transplantation and can be considered a useful additional tool in the global assessment of patients with advanced liver disease | furthermore sarcopenia may represent an important prognostic factor for patients with hepatocellular carcinoma and for those undergoing liver transplantation and can be considered a useful additional tool in the aren global assessment ain of patients with advanced liver disease |
opioids are associated with side effects in the treatment of moderatetosevere chronic cancer pain | opioids are associated youve with side effects in the treatment of moderatetosevere chronic cancer pain |
oral combination of opioid agonistantagonist oxycodonenaloxone attenuates gastrointestinal side effects however evidence on highdose oxnpr treatment is scant | oral combination of opioid agonistantagonist oxycodonenaloxone gastrointestinal side effects however evidence on highdose again oxnpr treatment is scant |
this study evaluates the efficacy and tolerability of highdose oxnpr in chronic cancer pain | this study abdicates the this efficacy and tolerability of highdose oxnpr in chronic cancer aine |
additional endpoints assessed at every visit were the impact of pain on quality of life breakthrough cancer pain episodes opioid dosage escalation index bowel dysfunction safety and other side effects | additional endpoints assessed at every visit were the impact of pain on quality of life breakthrough cancer pain episodes opioid dosage escalation index bowel dysfunction safety wouldnt and other side effects |
oxnpr resulted in a significant reduction in pain over time and the number of daily declined | oxnpr resulted in a significant reduction in pain over time thatll and the number of daily assigned |
daily dosage of oxnpr slightly increased | daily dosage of oxnpr slightly increased |
the impact of pain on qol abated and bowel function improved overtime | the of but pain me on qol abated and bowel function improved overtime |
after the switch to oxnpr the number of patients complaining for side effects decreased overall laxatives and antiemetic use also declined significantly | after the switch to oxnpr the number of patients complaining for side effects decreased overall laxatives and antiemetic also declined significantly |
oxnpr was highly effective and well tolerated even at high doses in cancer patients with chronic pain | oxnpr was highly effective and well tolerated even at high doses in cancer patients with chronic pain |
the agonistantagonist combination rapidly alleviated pain and its impact on life style reducing the number of btcp and improving opioid side effects | the agonistantagonist combination those rapidly alleviated pain and its impact on life style reducing the number of btcp this and improving opioid side effects |
gastric stenosis is a potential adverse event postlaparoscopic sleeve gastrectomy | gastric stenosis is a potential adverse me event down postlaparoscopic sleeve gastrectomy |
endoscopic management is preferred however there is significant variation in therapeutic strategies with no defined algorithm | endoscopic management is preferred however there is significant variation in therapeutic strategies with no defined algorithm |
this study aims to describe the safety and efficacy of a predefined stepwise algorithm for endoscopic management of gs postlsg | this study aims to describe the safety and efficacy of a reassigned stepwise algorithm for endoscopic management too of gs postlsg |
patients who did not respond or opted out of ongoing endoscopic therapy were offered revision rouxeny gastric bypass | patients did not respond or opted out of ongoing endoscopic therapy were offered both revision rouxeny gastric bypass |
one patient suffered a tear to the muscularis propria with balloon dilation which was managed conservatively | one patient suffered a tear do the muscularis propria with balloon dilation which was managed conservatively |
pagisym scores revealed that the strongest response to therapy based on mean reduction of score ± sd was in the following items nausea heartburn during day heartburn on lying down reflux during day and reflux on lying down | pagisym scores thatll revealed that the strongest response to therapy based we mean reduction of score ± sd was in the following items nausea heartburn during day heartburn on lying down reflux during day and reflux on lying down |
two patients failed endoscopic therapy and underwent rygb | two patients failed endoscopic therapy and underwent rygb |
endoscopic management of gs using the described algorithmic approach is safe and effective postlsg | endoscopic management of her gs fusing the described algorithmic approach is safe and effective postlsg |
patients with severe stenosis or helical stenosis are likely to require revision rygb | patients with severe stenosis or helical stenosis are doesnt likely to require revision whom rygb |
we aimed to define the prevalence of postoperative hypocalcemia and identify clinical predisposing factors | we aimed to define the prevalence of postoperative hypocalcemia and identify clinical ours predisposing factors |
the study was conducted in an academic medical center usa | the study was conducted in an epidemic medical center usa |
patients with revision surgeries were excluded | patients with decision surgeries re were excluded |
nine hundred ninetynine patients fulfilled the criteria above | nine hundred ninetynine patients fulfilled the criteria above |
patients who are predisposed to developing postoperative hypocalcemia such as those with preoperative renal impairment or postoperative vitamin d deficiency and renal insufficiency may benefit from increased surveillance and prevention strategies | patients who are predisposed to developing postoperative hypocalcemia such as those with postoperative renal impairment or postoperative vitamin d deficiency and renal insufficiency aaa benefit from increased surveillance and prevention strategies |
gastroscopymay not only allow identification of gastric injury but may also facilitate prompt repair | gastroscopymay not only allow identification of gastric injury but may also facilitate prompt repair |
physical examination and computed tomography showed no evidence of gastric injury | physical examination and computed tomography showed evidence of gastric ain gingery |
gastroscopy identified a ruptured artery and gastric perforation | gastroscopy identified a ruptured artery and gastric perforation |
repaired immediately using titanium clips | repaired immediately dont using titanium clips |
after operation the patient recovered well without complications | after operation the patient recovered well without complications |
no more bleeding was observed after the operation | no more bleeding was observed after the operation |
lesson subsections interventional endoscopy has evolved as an effective alternative to primary surgery for treating gastrointestinal perforation | lesson subsections interventional endoscopy has evolved as an effective alternative to primary surgery for treating gastrointestinal are perforation |
the evaluation of the patient with hematochezia can be complex because of the broad differential diagnosis and the number of management strategies available | the evaluation of the itself patient with hematochezia can be complex because of the broad differential diagnosis and the number gov management strategies by available |
in this article a simplified approach to the history and physical examination is presented with management illustrated in a caseoriented manner | in this article a simplified approach to the history and some physical examination is presented with management which illustrated in caseoriented manner |
to study the clinical effect and safety of two doses of lowdose perioperative dexamethasone on pain and recovery after total knee arthroplasty | to study the clinical effect and safety what of two doses of lowdose perioperative dexamethasone on pain and recovery after total knee arthroplasty |
postoperative fatigue was relieved and the analgesic and antiemetic rescue consumption was reduced | postoperative fatigue was relieved and the analgesic and antiemetic rescue consumption was reduced |
and range of motion | and range of motion |