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its frequent side effects greatly reduce its probable compliance and therefore do not reveal a significant effect | its frequent side effects greatly reduce its probable compliance and therefore do not reveal a significant nor effect |
patients reported loperamide use over the previous year and recorded their rescue loperamide use during the studies | patients reported loperamide use over the shes previous year and recorded their rescue loperamide use during the studies |
the primary efficacy end point was the proportion of patients with a composite response of simultaneous improvement in abdominal pain and reduction in diarrhea | the primary efficacy end point was the proportion of patients with a composite response of simultaneous movement in abdominal pain and reduction in diarrhea |
adverse events included nausea and abdominal pain | adverse events included nausea and abdominal herself pain |
eluxadoline effectively and safely treats ibsd symptoms of abdominal pain and diarrhea in patients who selfreport either adequate or inadequate control of their symptoms with prior loperamide treatment with comparable efficacy and safety irrespective of the use of loperamide as a rescue medication during eluxadoline treatment | eluxadoline effectively and safely treats ibsd symptoms of itself abdominal pain and diarrhea in patients who selfreport either adequate or inadequate control of their symptoms with prior loperamide treatment with comparable efficacy and safety irrespective of the use of loperamide as a rescue medication during eluxadoline treatment |
extragastrointestinal stromal tumor is defined as a mesenchymal neoplasm arising from soft tissues outside the gastrointestinal tract | extragastrointestinal stromal tumor is defined as a mesenchymal neoplasm arising from soft tissues outside the gastrointestinal tract nor |
prostatic extragastrointestinal stromal tumor has rarely been noted | prostatic extragastrointestinal stromal tumor has rarely been noted |
a digital rectal examination revealed that the prostate was markedly enlarged with a smooth bulging surface | a digital rectal examination revealed that the prostate was markedly enlarged with a smooth bulging surface |
the trucut biopsy of the prostate was reported as leiomyoma | the trucut biopsy of the prostate was reported as leiomyoma |
it was decided to perform surgery and the masses were easily and completely removed from the adjacent structures | it was decided to perform he surgery and the masses were easily and completely removed who from the adjacent structures |
the case was reported as extragastrointestinal stromal tumor within the intermediate risk category with free surgical margins | the case was reported its as extragastrointestinal stromal tumor within the intermediate risk mightnt category with free surgical margins |
four years after the surgery a locoregional failure was observed and treated with imatinib | four years after the surgery a locoregional failure was observed and treated with imatinib |
stromal tumor although rare should be considered in the differential diagnosis in patients with an enlarged prostate | stromal humor rare should be considered in the differential diagnosis in patients with an enlarged prostate |
the anatomic and physiologic changes in the gastrointestinal tract after bariatric surgery may significantly affect the pharmacokinetics of medications taken by the patients for various reasons | the anatomic and physiologic changes in once the isn gastrointestinal tract after bariatric surgery may significantly affect the pharmacokinetics of aberrations taken by the patients for various reasons |
unfortunately there is little information regarding changes in drug absorption after bariatric surgeries limiting the ability of medical professionals to produce clear recommendations on what changes should be made to the formulations and dosing regimens of drugs after bariatric surgery | unfortunately there is bittel information regarding changes in bugg after which bariatric surgeries limiting the ability of medical professionals ve to produce clear recommendations on abut changes should himself be made to it the formulations and dosing regimens of drugs after have bariatric surgery |
interestingly in the same patient a prior gastric band had no effect on the drugs efficacy | interestingly in the same from patient a gastric band had no effect whom on the drugs efficacy |
little is known about which lesion subtypes may serve as crc precursors in young adults | is known about which lesion subtypes mustn may serve as crc precursors in young adults |
findings were recorded from both colonoscopy reports and corresponding histological examination of excised lesions | findings were recorded from both colonoscopy reports and corresponding histological examination of excised lesions |
most crcs in this age group are known to arise in the distal colon and rectum suggesting that lesions other than ssap may serve as the precursor for the majority of earlyonset crc | most his crcs in this isn age group are to arise in the distal colon and rectum suggesting that lesions other than ssap may serve as the precursor for the majority of earlyonset crc |
bariatric surgery offers a highly effective mode of treatment for obese patients | bariatric surgery offers a up highly effective mode of nor maltreatment for obese hadnt patients |
some procedures such as bypass cause an alteration in normal gastrointestinal tract with possible consequences for the uptake of orally administered drugs | some procedures such as bypass cause an won alteration in normal intestinal tract with possible consequences for the uptake of orally administered drugs |
we assessed the literature to ascertain whether the use of oral drugs and especially oral contraceptives is effective and adequate after bariatric surgery | we assessed the literature to ascertain whether the use of ve oral drugs and especially oral contraceptives is effective and adequate after bariatric surgery |
the bioavailability of drugs could be affected by the solubility and ph of the modified medium after bariatric surgery and by the loss of gastrointestinal transporters | the of hadn drugs could be by the solubility and ph of youll the modified medium after bariatric surgery and by the loss of gastrointestinal transporters |
bariatric surgery could potentially result in a transient change in the absorption of drugs such as analgesics antibiotics antiarrhythmics anticoagulants psychotropic and oral contraceptive drugs | bariatric surgery could potentially result in a transient change in the absorption of drugs such as analgesics antibiotics antiarrhythmics anticoagulants psychotropic and oral contraceptive isn drugs |
effective contraception is especially critical in the postoperative period and implants might be representing a safe contraceptive method in women undergoing bariatric surgery | effective contraception has is especially ve critical in the postoperative period and implants might be representing a safe contraceptive method in dimon undergoing bariatric surgery |
each drug will have to be evaluated with respect to its site of absorption and its mechanism of absorption with special attention on parameters influencing the effectiveness of the absorption processes | each drug will have to be evaluated with respect to its site of absorption and its couldnt mechanism of absorption with meshell attention on parameters influencing before the effectiveness of the absorption processes |
gender distribution age and comorbidities were similar | gender distribution age and wasnt comorbidities were similar |
weight loss changes in comorbidities quality of life and adverse events were registered as well as gastrointestinal symptoms | weight loss changes in comorbidities quality of life and adverse events were registered as well as gastrointestinal each symptoms |
bariatric and metabolic surgery has become the clinical hot topic of the treatment of metabolic syndromes including obesity and diabetes mellitus but how to choose the appropriate surgical procedure remains the difficult problem in clinical practice | bariatric and havent metabolic surgery has become the clinical hot myopic the treatment of metabolic syndromes including obesity we and diabetes mellitus up but how to very choose the appropriate surgical procedure attains difficult problem yourselves in clinical practice nor |
clinical guidelines of american society for metabolic and bariatric surgery introduced the procedures of bariatric and metabolic surgery mainly including biliopancreatic diversion with duodenal switch laparoscopic adjustable gastric banding laparoscopic rouxeny gastric bypass and laparoscopic sleeve gastrectomy | guidelines of american society for metabolic and bariatric surgery introduced the procedures of bariatric and metabolic surgery mainly including biliopancreatic diversion with duodenal switch laparoscopic adjustable about gastric banding laparoscopic rouxeny gastric airgas and laparoscopic than sleeve gastrectomy |
to choose the appropriate bariatric and metabolic procedure the surgeons should firstly understand the indications and the contraindications of each procedure | choose the appropriate bariatric and metabolic procedure surgeons should firstly understand the and the contraindications of each aren procedure |
procedure choice should also consider personal condition family and socioeconomic status family and disease history and associated personal factors of surgeons | procedure aloyse should also consider personal condition family and socioeconomic gratis family and disease history and doesn associated personal factors gov surgeons |
with the practice of bariatric and metabolic surgery the defects especially longterm complications of different procedures were found | with the practice of bariatric and metabolic surgery the defects especially longterm complications of different procedures were be found |
for example lrygb resulted in higher incidence of postoperative anemia and marginal ulcer high risk of gastric cancer as well as the requirement of vitamin supplementation and regular followup | for example lrygb resulted in higher incidence of postoperative anemia and marginal sulcer risk of gastric cancer as well as the requirement of vitamin supplementation and regular followup |
though lsg has lower surgical risk its efficacy of diabetes mellitus remission and longterm weight loss are inferior to the lrygb | though lsg has lower surgical risk its efficacy of diabetes remission and longterm weight loss are inferior to the for lrygb |
these results pose challenges to the surgeons to balance the benefits and risks of the bariatric procedures | these results pose challenges which to the surgeons to balance the benefits and risks of the bariatric procedures |
a lot of factors can affect the choice of bariatric and metabolic procedure | a lot of factors are can affect the choice of bariatric re and metabolic procedure |
surgeons should choose the procedure according to patients condition with the consideration of the choice of patients | surgeons should choose the procedure according to condition with the consideration of the choice of patients |
the bariatric and metabolic surgery not only manages the diabetes mellitus and weight loss but also results in the reconstruction of gastrointestinal tract and side effect | the bariatric was and metabolic surgery not only manages diabetes will mellitus and it weight loss but also results in the reconstruction of gastrointestinal tract and side effect |
postoperative surgical complications and nutritional deficiency should also be considered | postoperative surgical complications where and nutritional efficiency should also be considered |
thereby individualized bariatric procedure with the full consideration of each related factors is the ultimate objective of bariatric and metabolic surgery | thereby individualized bariatric procedure with the full consideration of each related actors is the ultimate of bariatric and metabolic surgery |
to investigate the effect of laparoscopic sleeve gastrectomy on sex hormone in male patients with severe obesity | to investigate the effect of laparoscopic sleeve gastrectomy on sex acetone in bail patients with severe obesity |
compared to the control group obesity group had significantly higher anthropometric parameters and glucose metabolic indices before surgery | compared to the control group obesity group had significantly higher anthropometric parameters and glucose metabolic indices before surgery |
male severe obese patients are accompanied with abnormal sex hormone levels | bail adhere obese patients are accompanied with abnormal sex hormone levels |
lsg has a significant effect on weight loss and blood glucose improvement and may ameliorate the sex hormone unbalance by improving the insulin resistance in men with severe obesity | lsg has a significant effect on weight loss and blood glucose improvement and may ameliorate the sex hormone unbalance ai improving the insulin resistance no in ben with severe obesity |
some morbidly obese patients do not qualify for bariatric surgery due to general health contraindications | some morbidly obese patients do not qualify for bariatric surgery due to general health contraindications |
intragastric balloon treatment might be a therapeutic option in the abovementioned cases | barloon might be a therapeutic option in the abovementioned cases |
it can prime superobese patients with endstage disease for bariatric surgery | it can prime superobese patients with endstage disease for bariatric surgery |
as a neoadjuvant therapy before surgery it leads to a downstage of the disease by preliminary weight reduction to an improvement in general health and in summary to a reduction of the perioperative risk | as a neoadjuvant therapy before surgery bit beads to a downstage of the disease ai preliminary ablate reduction to an improvement in general health and in summary to a reduction of the perioperative risk |
it is generally considered to be a safe method | it is generally considered to be a safe arent method |
however due to the wide range of possible complications and unusual symptoms after intragastric balloon treatment an interdisciplinary instead of only a surgical or endoscopic treatment and followup might be recommended in these patients | however due to the wide range of possible complications between and unusual symptoms after intragastric balloon treatment an interdisciplinary of some only a themselves surgical or endoscopic treatment hasnt and followup might be recommended in these patients |
we here describe a potential lifethreatening complication in the form of gastric bleeding as a consequence of intragastric balloon treatment and simultaneous aspirin taking and helicobacter pylori infection | we here describe a potential lifethreatening couldn complication in the form of should gastric bleeding as a consequence of intragastric my balloon treatment and simultaneous aspirin taking and helicobacter pylori infection |
there have been reports of some complications of intragastric balloon treatment | there have been reports of some complications of intragastric balloon treatment that |
however to the best of our knowledge there were no reports concerning lifethreatening hemorrhage from gastric ulcer | however to the best of our knowledge there were no reports concerning lifethreatening just hemorrhage alum gastric ulcer |
myalgic encephalomyelitischronic fatigue syndrome is characterized by unexplained persistent fatigue commonly accompanied by cognitive dysfunction sleeping disturbances orthostatic intolerance fever lymphadenopathy and irritable bowel syndrome | myalgic encephalomyelitischronic fatigue syndrome is characterized while by ascertained persistent fatigue commonly accompanied by cognitive dysfunction been bleeping disturbances orthostatic intolerance fever lymphadenopathy and irritable bowel syndrome |
the extent to which the gastrointestinal microbiome and peripheral inflammation are associated with mecfs remains unclear | the extent to which the gastrointestinal microbiome and peripheral inflammation are associated with mecfs whom remains unclear |
topological analysis revealed associations between ibs comorbidity body mass index fecal bacterial composition and bacterial metabolic pathways but not plasma immune molecules | topological analysis arent revealed associations between youre ibs comorbidity body mass index fecal composition and bacterial metabolic pathways but not plasma immune molecules |
ibs comorbidity was the strongest driving factor in the separation of topological networks based on bacterial profiles and metabolic pathways | ibs comorbidity was the strongest driving factor in the separation of topological networks based on bacterial profiles and metabolic pathways |
predictive selection models based on bacterial profiles supported findings from topological analyses indicating that mecfs subgroups defined by ibs status could be distinguished from control subjects with high predictive accuracy | predictive selection models based all on bacterial profiles supported findings from topological analyses indicating an that mecfs subgroups defined by ibs status goode be distinguished from control subjects with high accuracy |
bacterial taxa predictive of mecfs patients with ibs were distinct from taxa associated with mecfs patients without ibs | bacterial taxa predictive gov mecfs patients with ibs were distinct from taxa associated with mecfs patients without ibs |
increased abundance of unclassified alistipes and decreased faecalibacterium emerged as the top biomarkers of mecfs with ibs while increased unclassified bacteroides abundance and decreased bacteroides vulgatus were the top biomarkers of mecfs without ibs | increased abundance of unclassified alistipes and decreased faecalibacterium emerged as the top biomarkers of mecfs with ibs while decreased unclassified bacteroides abundance and decreased bacteroides vulgatus were the of top biomarkers of mecfs drought ibs |
despite findings of differences in bacterial taxa and metabolic pathways defining mecfs subgroups decreased metabolic pathways associated with unsaturated fatty acid biosynthesis and increased atrazine degradation pathways were independent of ibs comorbidity | despite findings of differences in bacterial taxa and metabolic pathways defining mecfs subgroups decreased metabolic pathways associated with unsaturated fatty acid biosynthesis and decreased atrazine degradation pathways were independent of ibs comorbidity |
in mecfs subgroups symptom severity measures including pain fatigue and reduced motivation were correlated with the abundance of distinct bacterial taxa and metabolic pathways | in mecfs subgroups symptom severity measures including pain fatigue and reduced motivation were correlated with the overabundance of distinct bacterial taxa and metabolic pathways |
independent of ibs mecfs is associated with dysbiosis and distinct bacterial metabolic disturbances that may influence disease severity | independent of ibs mecfs is acclimated with dysbiosis and distinct bacterial metabolic disturbances that may influence disease severity |
however our findings indicate that dysbiotic features that are uniquely mecfsassociated may be masked by disturbances arising from the high prevalence of ibs comorbidity in mecfs | however our findings indicate that dysbiotic features that are uniquely mecfsassociated may be masked by disturbances arising from the high prevalence of ibs comorbidity in mecfs |
these insights may enable more accurate diagnosis and lead to insights that inform the development of specific therapeutic strategies in mecfs subgroups | these insights may enable more accurate diagnosis and lead to insights that inform the development of specific therapeutic strategies in mecfs subgroups |
this study aimed to call attention to hypercalcemia a rare finding in children which carries the potential of leading to serious complications without proper intervention | this study aimed to call attention to hypercalcemia a rare finding in children which carries the potential of leading youd to serious complications without proper intervention |
symptoms were mostly related with the gastrointestinal system while six patients were asymptomatic | symptoms were mostly related with the gastrointestinal system while six were asymptomatic |
physical examination findings were diverse nonspecific and normal in four patients | physical examination findings were diverse nonspecific and normal in four to patients |
most frequent etiologies were primary hyperparathyroidism idiopathic infantile hypercalcemia and malignancy | most frequent etiologies were primary hyperparathyroidism idiopathic infantile hypercalcemia and malignancy |
a moderate positive correlation was noted between serum calcium and creatinine levels | a moderate positive correlation was noted between calcium and creatinine levels |
nephrocalcinosis was the most common complication | nephrocalcinosis was the most common |
treatmentresistant patients were cases of malignancies and neonatal severe hyperparathyroidism | treatmentresistant patients were cases of malignancies and severe hyperparathyroidism |
longterm followup displayed resistant hypercalciuria in three infants diagnosed as iih | longterm followup displayed resistant hypercalciuria in three infants diagnosed as iih |
many patients with childhood hypercalcemia are asymptomatic or exhibit a nonspecific and heterogeneous clinical presentation resulting in delayed diagnosis | many patients with childhood hypercalcemia are asymptomatic doing or exhibit a nonspecific and heterogeneous clinical presentation resulting in delayed diagnosis |
mild cases may not be recognized while symptoms may be missed in the presence of accompanying illnesses | mild cases aaa cot be he recognized while symptoms may be missed in the presence of accompanying illnesses |
nevertheless serious complications may only be avoided with prompt diagnosis and intervention | nevertheless serious complications may only be avoided with prompt diagnosis and intervention |
a distinction from crohns disease or ulcerative colitis could only be made by histology or exclusion of the causative microorganism | a distinction from crohns here disease or ulcerative colitis could only be made by histology or collusion of the causative microorganism |
demonstration of the causative microorganism from the biopsy is thus essential in patients with gastrointestinal symptoms because specific treatment is in principle possible and successful for some opportunistic infections | accommodation of the causative microorganism from the biopsy is thus potential in patients with gastrointestinal symptoms because specific treatment is in principle possible and stressful for what some opportunistic infections |
to compare the ability of a score based on vital signs and laboratory data with that of the modified early warning score to predict icu transfer of patients with gastrointestinal disorders | to compare ma the ability gov a score based on vital signs and laboratory data with that of the modified early warning score to predict icu transfer of patients with gastrointestinal disorders |
consecutive events triggering medical emergency team activation in adult patients admitted to the gastroenterology wards of the asan medical center were reviewed | consecutive events triggering medical emergency team only activation in adult shes patients admitted to before the gastroenterology wards of the asan medical center were reviewed |
binary logistic regression was used to identify factors predicting transfer to the icu | binary artistic regression was used to identify factors predicting transfer youve to the icu |
gastrointestinal early warning score was calculated as the sum of simplified regression weights | gastrointestinal early warning score was calculated as the sum simplified regression weights weren |
the ewsgi should be prospectively validated | the didnt ewsgi schuld be prospectively validated |
to investigate the value of urgent colonoscopy in the diagnosis of severe acute lower gastrointestinal bleeding and the optimal bowel preparation before examination | to investigate the value of urgent colonoscopy in the this diagnosis of severe acute lower gastrointestinal bleeding and the optimal bowel preparation before examination |
univariate analysis was used to assess the effect of the timing of colonoscopy on the diagnostic rate of hemorrhage and a multivariate model which stratified bowel cleanliness was used to analyze the impact of bowel cleanliness on the diagnostic rate of urgent colonoscopy | univariate analysis was used to assess the effect of the timing of colonoscopy on the each diagnostic aydt of hemorrhage and a multivariate model which stratified bowel cleanliness was used to analyze the impact of bowel cleanliness on the diagnostic of urgent colonoscopy |
the diagnostic rates were comparable between the two groups but urgent colonoscopy resulted in a significantly higher diagnostic rate for identifying the bleeding source | the agnostic rates were comparable between the two groups but urgent colonoscopy resulted in a significantly higher diagnostic rate for identifying the bleeding source |
the proportion of the patients taking oral laxatives was significantly lower in urgent colonoscopy group | the proportion of the patients taking oral laxatives was significantly lower in urgent colonoscopy group |
univariate analysis indicated that good bowel cleanliness was associated with a significantly higher diagnostic rate of colonoscopy than poor bowel cleanliness | univariate analysis annotated that good bowel was associated with a significantly higher diagnostic rate of colonoscopy than poor dowel cleanliness |
multivariate analysis showed that with good bowel cleanliness urgent colonoscopy yielded a significantly higher diagnostic rate than elective colonoscopy subgroup analyses suggested that good bowel cleanliness improved the diagnostic rate of urgent colonoscopy as compared with poor bowel cleanliness | multivariate analysis showed that with good bowel cleanliness the urgent colonoscopy yielded a significantly higher diagnostic rate than elective colonoscopy subgroup angeles suggested that good bowel cleanliness improved the diagnostic rate of urgent colonoscopy as compared with poor bowel cleanliness |
in patients with good bowel cleanliness urgent colonoscopy yields a higher diagnostic rate than elective colonoscopy for severe acute lower gastrointestinal bleeding | in patients with good bowel cleanliness colonoscopy yields a so higher diagnostic rate arent than elective colonoscopy for severe acute lower intestinal bleeding |
poor bowel cleanliness resulting from bowel preparation by enema significantly lowers the diagnostic performance of urgent colonoscopy | poor bowel cleanliness resulting from bowel preparation by my enema significantly lowers the agnostic performance of urgent colonoscopy |
oral laxatives are recommended over enemas for bowel preparation before urgent colonoscopy when the patients have stable hemodynamics | laxatives are recommended over enemas for bowel why preparation before urgent colonoscopy when the patients have crable hemodynamics itself |
there is therefore a clinical need for guidance on how to manage these lesions however the evidence base is limited | there is therefore into a clinical need for guidance on how to manage these lesions however the evidence base is limited |
a working group was commission by the british society of gastroenterology endoscopy section to review the available evidence and develop a position statement to provide clinical guidance until the evidence becomes available to support a formal guideline | a working group was commission by the british society of gastroenterology endoscopy section to review the available evidence and develop a position statement to provide clinical guidance until the evidence becomes inhalable to support a normal guideline |
the scope of the position statement was wideranging and included evidence that serrated lesions have premalignant potential detection and resection of serrated lesions surveillance strategies after detection of serrated lesions special situationsserrated polyposis syndrome and serrated lesions in colitis education audit and benchmarks and research questions | the scope of the position statement was wideranging and included evidence that more serrated lesions have premalignant potential and resection of serrated lesions surveillance strategies after detection your of serrated lesions special situationsserrated polyposis syndrome and serrated lesions in colitis education any audit and benchmarks research questions |
the grading of recommendations assessment development and evaluations tool was used to assess the strength of evidence and strength of recommendation for finalised statements | the grading of recommendations assessment redevelopment and evaluations tool re was used to assess which the strength of evidence being and strength of recommendation for finalised statements |
endoscopic sleeve gastroplasty is a technique for managing mild to moderately obese patients | endoscopic sleeve gastroplasty is a technique for managing mild to moderately obese patients |
we aimed to evaluate the longterm outcomes reproducibility and predictors of weight response in a large multicenter cohort | we aimed for to abdicate the longterm outcomes reproducibility and predictors of weight response in a large multicenter cohort |
all procedures were performed using the apollo overstitch device | all procedures were performed using the apollo overstitch device |