jeffreygwang/pythia_dedupe_mia_0-70000_70000-98500

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Instructions for performing these tasks from the Administration Console are provided in the Administration Console online help. \|link:../security-guide/toc.html#GSSCG[Security Guide] \|Provides instructions for configuring and administering GlassFish Server security. \|link:../application-deployment-guide/toc.html#GSDPG[Application Deployment Guide] \|Explains how to assemble and deploy applications to the GlassFish Server and provides information about deployment descriptors. \|link:../application-development-guide/toc.html#GSDVG[Application Development Guide] \|Explains how to create and implement Java Platform, Enterprise Edition (Java EE platform) applications that are intended to run on the GlassFish Server. These applications follow the open Java standards model for Java EE components and application programmer interfaces (APIs). This guide provides information about developer tools, security, and debugging. \|link:../add-on-component-development-guide/toc.html#GSACG[Add-On Component Development Guide] \|Explains how to use published interfaces of GlassFish Server to develop add-on components for GlassFish Server. This document explains how to perform only those tasks that ensure that the add-on component is suitable for GlassFish Server. \|link:../embedded-server-guide/toc.html#GSESG[Embedded Server Guide] \|Explains how to run applications in embedded GlassFish Server and to develop applications in which GlassFish Server is embedded. \|link:../ha-administration-guide/toc.html#GSHAG[High Availability Administration Guide] \|Explains how to configure GlassFish Server to provide higher availability and scalability through failover and load balancing. \|link:../performance-tuning-guide/toc.html#GSPTG[Performance Tuning Guide] \|Explains how to optimize the performance of GlassFish Server. \|link:../troubleshooting-guide/toc.html#GSTSG[Troubleshooting Guide] \|Describes common problems that you might encounter when using GlassFish Server and explains how to solve them. \|link:../error-messages-reference/toc.html#GSEMR[Error Message Reference] \|Describes error messages that you might encounter when using GlassFish Server. \|link:../reference-manual/toc.html#GSRFM[Reference Manual] \|Provides reference information in man page format for GlassFish Server administration commands, utility commands, and related concepts. \|link:../../openmq/mq-release-notes/toc.html#GMRLN[Message Queue Release Notes] \|Describes new features, compatibility issues, and existing bugs for Open Message Queue. \|link:../../openmq/mq-tech-over/toc.html#GMTOV[Message Queue Technical Overview] \|Provides an introduction to the technology, concepts, architecture, capabilities, and features of the Message Queue messaging service. \|link:../../openmq/mq-admin-guide/toc.html#GMADG[Message Queue Administration Guide] \|Explains how to set up and manage a Message Queue messaging system. \|link:../../openmq/mq-dev-guide-jmx/toc.html#GMJMG[Message Queue Developer's Guide for JMX Clients] \|Describes the application programming interface in Message Queue for programmatically configuring and monitoring Message Queue resources in conformance with the Java Management Extensions (JMX). \|link:../../openmq/mq-dev-guide-java/toc.html#GMJVG[Message Queue Developer's Guide for Java Clients] \|Provides information about concepts and procedures for developing Java messaging applications (Java clients) that work with GlassFish Server. \|link:../../openmq/mq-dev-guide-c/toc.html#GMCCG[Message Queue Developer's Guide for C Clients] \|Provides programming and reference information for developers working with Message Queue who want to use the C language binding to the Message Queue messaging service to send, receive, and process Message Queue messages. \|======================================================================= [[GSACG00080]][[giprl]] [[related-documentation]] Related Documentation ~~~~~~~~~~~~~~~~~~~~~ The following tutorials explain how to develop Java EE applications: * http://docs.oracle.com/javaee/7/firstcup/doc/home.html[Your First Cup: An Introduction to the Java EE Platform] (`http://docs.oracle.com/javaee/7/firstcup/doc/home.html`). For beginning Java EE programmers, this short tutorial explains the entire process for developing a simple enterprise application. The sample application is a web application that consists of a component that is based on the Enterprise JavaBeans specification, a JAX-RS web service, and a JavaServer Faces component for the web front end. * http://docs.oracle.com/javaee/7/tutorial/doc/home.html[The Java EE 7 Tutorial] (`http://docs.oracle.com/javaee/7/tutorial/doc/home.html`). This comprehensive tutorial explains how to use Java EE 7 platform technologies and APIs to develop Java EE applications. Javadoc tool reference documentation for packages that are provided with GlassFish Server is available as follows. * The API specification for version 7 of Java EE is located at `http://docs.oracle.com/javaee/7/api/`. * The API specification for GlassFish Server 4.0, including Java EE 7 platform packages and nonplatform packages that are specific to the GlassFish Server product, is located at `http://glassfish.java.net/nonav/docs/v3/api/`. Additionally, the http://www.oracle.com/technetwork/java/javaee/tech/index.html[Java EE Specifications] (`http://www.oracle.com/technetwork/java/javaee/tech/index.html`) might be useful. For information about creating enterprise applications in the NetBeans Integrated Development Environment (IDE), see the http://www.netbeans.org/kb/[NetBeans Documentation, Training & Support page] (`http://www.netbeans.org/kb/`). For information about the Java DB database for use with the GlassFish Server, see the http://www.oracle.com/technetwork/java/javadb/overview/index.html[Java DB product page] (`http://www.oracle.com/technetwork/java/javadb/overview/index.html`). The Java EE Samples project is a collection of sample applications that demonstrate a broad range of Java EE technologies. The Java EE Samples are bundled with the Java EE Software Development Kit (SDK) and are also available from the http://glassfish-samples.java.net/[Java EE Samples project page] (`http://glassfish-samples.java.net/`). [[GSACG00081]][[fwbkx]] [[typographic-conventions]] Typographic Conventions ~~~~~~~~~~~~~~~~~~~~~~~ The following table describes the typographic changes that are used in this book. [width="100%",cols="<14%,<37%,<49%",options="header",] \|======================================================================= \|Typeface \|Meaning \|Example \|`AaBbCc123` \|The names of commands, files, and directories, and onscreen computer output a\| Edit your `.login` file. Use `ls` `a` to list all files. `machine_name% you have mail.` \|`AaBbCc123` \|What you type, contrasted with onscreen computer output a\| `machine_name%` `su` `Password:` \|AaBbCc123 \|A placeholder to be replaced with a real name or value \|The command to remove a file is `rm` filename. \|AaBbCc123 \|Book titles, new terms, and terms to be emphasized (note that some emphasized items appear bold online) a\| Read Chapter 6 in the User's Guide. A cache is a copy that is stored locally. Do not save the file. \|======================================================================= [[GSACG00082]][[fquvc]] [[symbol-conventions]] Symbol Conventions ~~~~~~~~~~~~~~~~~~ The following table explains symbols that might be used in this book. [width="100%",cols="<10%,<26%,<28%,<36%",options="header",] \|======================================================================= \|Symbol \|Description \|Example \|Meaning \|`[ ]` \|Contains optional arguments and command options. \|`ls [-l]` \|The `-l` option is not required. \|`{ \\| }` \|Contains a set of choices for a required command option. \|`-
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10013, 253, 44604, 6200, 4102, 27, 3973, 352, 369, 42803, 313, 35, 1088, 3189, 1832, 45782, 13, 13936, 287, 351, 898, 34, 13, 14388, 868, 582, 840, 10501, 16234, 2739, 313, 8677, 16619, 293, 13, 378, 853, 2485, 13, 9872, 311, 357, 31834, 582, 285, 1024, 352, 3133, 281 ]	heelsfuck, double penetration .... and if you want something new I will try Do it for yoHouse Speaker Nancy Pelosi, D-Calif., on Thursday accused the White House of a "cover up," hours after the public release of a whistleblower's complaint alleging that President Donald Trump tried to solicit Ukraine to interfere in the 2020 election — and the administration sought to conceal that effort. "This is a cover-up. This is a cover-up," Pelosi repeared at her weekly press conference, her first since announcing a formal impeachment inquiry into Trump on Tuesday evening. Advertisement: Pelosi went on to read aloud a part of the whistleblower's complaint alleging that the White House had intervened to "lock down" all records of a July 25 phone call between Trump and Ukrainian President Volodymyr Zelensky. The call is at the center of the complaint. The whistleblower alleged the administration placed the transcript of Trump's call with Zelensky into a "computer system managed directly by the National Security Council (NSC) Directorate for Intelligence Programs," which the whistleblower described as a "standalone computer system reserved for codeword-level intelligence information, such as covert action." "According to White House officials I spoke with, this was 'not the first time' under this administration that a presidential transcript was placed into this codeword-level system solely for the purpose of protecting politically sensitive — rather than national security sensitive — information," the whistleblower wrote. Advertisement: Pelosi said those actions constituted a "cover-up." House Democrats have decided to narrow the focus of their inquiry to the allegations detailed in the whistleblower's complaint, she said. "Our consensus in our caucus is we will proceed under the auspices of where this matter is relevant and that is the Intelligence Committee," she added. The complaint alleged that Trump urged Zelensky to "initiate or continue an investigation" into Hunter Biden, the son of Joe Biden, who is currently vying for the Democratic nomination to challenge the president in the 2020 election. Advertisement: Trump also asked Zelensky to investigate allegations that Russian interference in the 2016 originated in Ukraine "with a specific request that the Ukrainian leader locate and turn over servers used by the Democratic National Committee (DNC) and examined by the U.S. cyber security firm CrowdStrike," the whistleblower alleged. (The emails of 2016 Democratic presidential nominee, Hillary Clinton, were hacked by Russian intelligence officials ahead of the 2016 election, as concluded by CrowdStrike. There is no evidence the server hacked by Russian agents in 2016 may have been hidden in Ukraine, as the president suggested.) Pelosi said she has not given committee chairs any deadlines, and only the facts would determine the schedule of the inquiry. Advertisement: "The timeline relates to how the Intelligence Committee proceeds and our timeline will spring from them," Pelosi said. (Notably, the House Judiciary Committee is the congressional panel that would draft articles of impeachment.) The speaker noted there was "no rush to judgement" on how House Democrats would proceed with their impeachment inquiry into Trump. She pointed out that while some members in her caucus want to rush into impeachment, it is important to "have an inquiry to further establish the facts." "We have to make a judgement in an inquiry as we go forward . . . There are some in our caucus who think, 'let's just have an impeachment.' No, we have to have an inquiry to further establish the facts," she said. "There is no rush to judgement and in some ways we are a jury — open to what might be exculpatory or not." Advertisement: "But every day, the sadness grows because the disregard for our Constitution that the President has becomes more clear," she continued. Pelosi underscored that the president's actions, as described in the whistleblower's complaint, "lifts this to a whole new terrain, a whole new level of concern about his lawlessness." "Use any metaphor you want — crossing the Rubicon, a new day has dawned . . ." she continued. "The facts are these: that the president of the United States, in his actions in a telephone call with a head of state, betrayed his office, our national security and the integrity of our election." Advertisement: "It's not the role of the president to shake down foreign leaders for his own political purposes, withholding taxpayer money to do so," she said. Her comments came as the acting director of national intelligence, Joseph Maguire, testified before the House Intelligence Committee about the complaint at a public hearing. Speaking of Maguire's decision to withhold the complaint from Congress last week, Pelosi said, "I think what the DNI did was [break] the law. The law is very clear — the DNI 'shall' convey the complaint to the Intelligence Committee."VisitBritain Shop is the official shop of the British Tourist Board, and has everything you need for a great trip to Britain, including travelcards, rail passes and tickets to a variety of attractions. Plan out your entire trip in advance, and save money at the same time! Britain Insider: A Local’s Guide To The Ultimate Weekend in Edinburgh Thursday 08 March 2018 A weekend in Britain always brims with local flavor, but it’s especially delicious when spent in the Scottish capital of Edinburgh. Amongst castles, cobbled streets, parks and museums, this historic region hosts more Michelin-starred restaurants than any other city in Britain outside London. (YUM.) Edinburgh local, Kate Bouchier-Hayes, has lived in the city for well over a decade. We polled the roller derby player and public relations professional on her favorite workouts, culture trips and, most importantly, FOOD for our Britain Insiders series. As it turns out, her responses make a picture-perfect weekender’s guide to the city. Edinburgh is a big city! Tell us about your neighborhood, Leith. I moved to Edinburgh about 15 years ago -- during that time, I've lived in quite a few different parts of the city, but Leith is my favourite. It has its own identity and character, and it’s a buzzing creative community in its own right. Leith is located just out of the city centre in Edinburgh's historic dock area, which gives it a strong sense of place. Leith provides the best of all worlds in that you have the stunning historic buildings and old maritime references that Edinburgh is famous for (which can be spotted throughout The Shore area), peace and tranquility (as offered by long walks along the Water of Leith), and a buzzing atmosphere created by fantastic bars and restaurants. Describe your typical weekend. 9 a.m. -- ExerciseI try and strike a balance in my weekends, so I like to get out for a decent walk (possibly to blow the cobwebs away from the night before!) in the morning. In Edinburgh, we are lucky to have a cracking range of options on our doorstep, many of which won’t be traditionally associated with the city. There’s a bracing beach walk along the old promenade at Portobello, a peaceful dander up the Water of Leith, or if you're feeling a bit more energetic, a climb up Arthur’s Seat. It’s always a challenge, but the sweeping views at the top of the sleeping volcano are always worth it! Aside from walks, jogging and outdoor bootcamps are big in Edinburgh, as the city's landscape is naturally so well-suited to challenging routes. I myself play roller derby with the Auld Reekie Roller Girls -- it’s not something Edinburgh is well-known for, but we actually have the biggest team in Scotland and one of the top-ranked in the UK! Exercise quota met, I usually catch up with pals for a bite to eat and a chat. Firm favorites for brunch and lunch right now are Urban Angel (always book ahead!), Roseleaf and Harmonium, a fab new vegan restaurant at The Shore. In recent years, Leith's exciting creative community has really developed, which is also key to what makes the area so special. New galleries and artist spaces are popping up, including the recently reopened Leith Custom House. This year, numerous venues in Leith, like the historic Leith Theatre, will be used as performance spaces as part of Edinburgh's famous Festivals. One of Edinburgh’s best qualities is how walkable it is. After living in the city for over 15 years, it amazes me that I still discover new parts of it. Exploring the Old Town on foot is certainly a must-do: the city is a warren of medieval cobbled streets and historical gems! I also love escaping to the rooftop terrace at The National Museum of Scotland, which has one of the most amazing 360-degree views of the city. 7 p.m. -- Dinner I LOVE eating. Seriously. Edinburgh has more restaurants per capita than any British city outside of London, so there's always plenty to choose from! For me, Edinburgh’s dining scene stands out in terms of quality and diversity. No matter your budget -- from a Michelin-starred restaurant to the most exciting street food and fresh produce markets -- Edinburgh has something to fit the bill. We've seen a few trends really grab the culinary scene recently: First it was burgers (Bread Meats Bread, Holyrood 9A, Nobles), then authentic Mexican food (El Cartel, Bodega, Topolabamba), and now it seems to
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9366, 310, 1469, 281, 2831, 253, 1386, 715, 7738, 247, 572, 301, 354, 29817, 1425, 2042, 15607, 281, 10007, 271, 10164, 478, 1050, 16062, 313, 2185, 10, 403, 23209, 390, 26187, 12016, 456, 281, 247, 2608, 665, 10095, 457, 85, 452, 731, 13, 352, 476, 1421, 281, 23753, 273, 7996, 941, 15, 1198, 1650, 13, 247, 2608, 342, 841 ]	, and countless other facets of the film are drawn from all over the continent and its diaspora, in a science-fiction celebration of the imaginary country of Wakanda, a high-tech utopia that is a fictive manifestation of African potential unfettered by slavery and colonialism. But it is first and foremost an African American love letter, and as such it is consumed with The Void, the psychic and cultural wound caused by the Trans-Atlantic slave trade, the loss of life, culture, language, and history that could never be restored. It is the attempt to penetrate The Void that brought us Alex Haley’s Roots, that draws thousands of African Americans across the ocean to visit West Africa every year, that left me crumpled on the rocks outside the Door of No Return at Gorée Island’s slave house as I stared out over a horizon that my ancestors might have traversed once and forever. Because all they have was lost to The Void, I can never know who they were, and neither can anyone else. In Cyprus, Estonia, the United Arab Emirates, and elsewhere, passports can now be bought and sold. “If you believe you are a citizen of the world, you are a citizen of nowhere. You don’t understand what citizenship means,” the British prime minister, Theresa May, declared in October 2016. Not long after, at his first postelection rally, Donald Trump asserted, “There is no global anthem. No global currency. No certificate of global citizenship. We pledge allegiance to one flag and that flag is the American flag.” And in Hungary, Prime Minister Viktor Orbán has increased his national-conservative party’s popularity with statements like “all the terrorists are basically migrants” and “the best migrant is the migrant who does not come.” Citizenship and its varying legal definition has become one of the key battlegrounds of the 21st century, as nations attempt to stake out their power in a G-Zero, globalized world, one increasingly defined by transnational, borderless trade and liquid, virtual finance. In a climate of pervasive nationalism, jingoism, xenophobia, and ever-building resentment toward those who move, it’s tempting to think that doing so would become more difficult. But alongside the rise of populist, identitarian movements across the globe, identity itself is being virtualized, too. It no longer needs to be tied to place or nation to function in the global marketplace. Deputy Attorney General Ron Rosenstein flew to Seattle for a press conference at which he announced little, but may have said a great deal. Back in the fall of 2001, exactly one month after the 9/11 attacks, a lawyer in Seattle named Tom Wales was murdered as he worked alone at his home computer at night. Someone walked into the yard of Wales’s house in the Queen Anne Hill neighborhood of Seattle, careful to avoid sensors that would have set off flood lights in the yard, and fired several times through a basement window, hitting Wales as he sat at his desk. Wales survived long enough to make a call to 911 and died soon afterwards. He was 49, divorced, with two children in their 20s. The crime was huge and dismaying news in Seattle, where Wales was a prominent, respected, and widely liked figure. As a young lawyer in the early 1980s he had left a potentially lucrative path with a New York law firm to come to Seattle and work as an assistant U.S. attorney, or federal prosecutor. That role, which he was still performing at the time of his death, mainly involved prosecuting fraud cases. In his off-duty hours, Wales had become a prominent gun-control advocate. From the time of his death onward, the circumstances of the killing—deliberate, planned, nothing like a robbery or a random tragedy—and the prominence of his official crime-fighting record and unofficial advocacy role led to widespread assumption that his death was a retaliatory “hit.” The Justice Department considers him the first and only U.S. prosecutor to have been killed in the line of duty. A week after 17 people were murdered in a mass shooting at Marjory Stoneman Douglas High School in Parkland, Florida, teenagers across South Florida, in areas near Washington, D.C., and in other parts of the United States walked out of their classrooms to stage protests against the horror of school shootings and to advocate for gun law reforms. A week after 17 people were murdered in a mass shooting at Marjory Stoneman Douglas High School in Parkland, Florida, teenagers across South Florida, in areas near Washington, D.C., and in other parts of the United States walked out of their classrooms to stage protests against the horror of school shootings and to advocate for gun law reforms. Student survivors of the attack at Marjory Stoneman Douglas High School traveled to their state Capitol to attend a rally, meet with legislators, and urge them to do anything they can to make their lives safer. These teenagers are speaking clearly for themselves on social media, speaking loudly to the media, and they are speaking straight to those in power—challenging lawmakers to end the bloodshed with their “#NeverAgain” movement. Why the ingrained expectation that women should desire to become parents is unhealthy In 2008, Nebraska decriminalized child abandonment. The move was part of a “safe haven” law designed to address increased rates of infanticide in the state. Like other safe-haven laws, parents in Nebraska who felt unprepared to care for their babies could drop them off in a designated location without fear of arrest and prosecution. But legislators made a major logistical error: They failed to implement an age limitation for dropped-off children. Within just weeks of the law passing, parents started dropping off their kids. But here's the rub: None of them were infants. A couple of months in, 36 children had been left in state hospitals and police stations. Twenty-two of the children were over 13 years old. A 51-year-old grandmother dropped off a 12-year-old boy. One father dropped off his entire family—nine children from ages one to 17. Others drove from neighboring states to drop off their children once they heard that they could abandon them without repercussion. Here are some readers with extra elements on this discussion—political, cultural, international. First, an American reader on the interaction of current concepts of masculinity and the nearly all-male population of mass gun murderers: The path to its revival lies in self-sacrifice, and in placing collective interests ahead of the narrowly personal. The death of liberalism constitutes the publishing world’s biggest mass funeral since the death of God half a century ago. Some authors, like conservative philosopher Patrick Deneen, of Why Liberalism Failed, have come to bury yesterday’s dogma. Others, like Edward Luce (The Retreat of Western Liberalism), Mark Lilla (The Once and Future Liberal), and Steven Levitsky and Daniel Ziblatt (How Democracies Die) come rather to praise. I’m in the latter group; the title-in-my-head of the book I’m now writing is What Was Liberalism. But perhaps, like God, liberalism has been buried prematurely. Maybe the question that we should be asking is not what killed liberalism, but rather, what can we learn from liberalism’s long story of persistence—and how can we apply those insights in order to help liberalism write a new story for our own time. A new study explores a strange paradox: In countries that empower women, they are less likely to choose math and science professions. Though their numbers are growing, only 27 percent of all students taking the AP Computer Science exam in the United States are female. The gender gap only grows worse from there: Just 18 percent of American computer-science college degrees go to women. This is in the United States, where many college men proudly describe themselves as “male feminists” and girls are taught they can be anything they want to be. Meanwhile, in Algeria, 41 percent of college graduates in the fields of science, technology, engineering, and math—or “STEM,” as it’s known—are female. There, employment discrimination against women is rife and women are often pressured to make amends with their abusive husbands. According to a report I covered a few years ago, Jordan, Qatar, and the United Arab Emirates were the only three countries in which boys are significantly less likely to feel comfortable working on math problems than girls are. In all of the other nations surveyed, girls were more likely to say they feel “helpless while performing a math problem.” The president’s son is selling luxury condos and making a foreign-policy speech. Who does Donald Trump Jr. speak for? Does the president’s son speak for the Trump Organization as he promotes luxury apartments in India? Does he speak for himself when he dines with investors in the projects? Does he speak for the Trump administration as he makes a foreign-policy speech in Mumbai on Friday? “When these sons go around all over the world talking about, one, Trump business deals and, two, … apparently giving speeches on some United States government foreign policy, they are strongly suggesting a linkage between the two,” Richard Painter, President George W. Bush’s chief ethics lawyer who is a professor of law at the University of Minnesota, told me. “Somebody, somewhere is going to cross the line into suggesting a quid pro quo.”If permissions to modify an Organizational Unit (OU) are intentionally or accidentally delegated to a user who shouldn’t have them, it can lead to leakage of sensitive data. For example, a user with these
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24, 14, 8089, 285, 898, 15, 19, 14, 8089, 387, 1638, 285, 3127, 277, 2059, 275, 253, 418, 2693, 2332, 15, 1723, 13, 253 ]	-0068642-g003){ref-type="fig"}. Bacteria retrieved from those plants were predominantly represented by members of the Leuconostocaceae, Bacillaceae, and Streptococcaceae families ([Figure 3B)](#pone-0068642-g003){ref-type="fig"} and specifically classified as species of Leuconostoc , Lactococcus , Bacillus, and Exiguobacterium ([Figure 5)](#pone-0068642-g005){ref-type="fig"}. ![Bacterial diversity phyllosphere differs between season of planting.\ The UPGMA dendrogram was made in QIIME using weighted UniFrac distance data between phyllosphere microbiota from 223 plants. Tree branches in blue correspond to plants from the E09 and E10 trials and red branches represent samples from the L09 and L10 trials. Clusters I and II were identified as two major sample groups. Relative sequence abundances of the top 21 taxonomic groups are shown in the order of sequence abundance. The heat map indicates a range of proportional sequence abundance in each sample (minimum: 0%; maximum: 87%).](pone.0068642.g005){#pone-0068642-g005} Temporal and irrigation effects on the phyllosphere microbiota {#s3.5} -------------------------------------------------------------- Within individual field trials, the bacterial composition on lettuce was typically distinct at each time point ([Table 1)](#tab1){ref-type="table"}. These differences were at least partially explained by the increased Phylogenetic Diversity (alpha-diversity) on leaves from plants collected at 21 dpi compared to plants at either 7 or 14 dpi ([Figure 6)](#pone-0068642-g006){ref-type="fig"}. The Chao1 species richness metric also positively correlated with the PD estimator (r^2^=0.89, data not shown). Similarly, temporal changes in the bacterial diversity were identified according to PCoA on Unifrac distances. For example, a temporal change in bacterial composition on lettuce was evident between 7 dpi and 21 dpi in L10 ([Figure 7A)](#pone-0068642-g007){ref-type="fig"}. At 14 dpi, the microbiota were typically similar to plants collected at either 7 dpi or 21 dpi, possibly indicating a transition from lower to higher bacterial diversity ([Figure 7A)](#pone-0068642-g007){ref-type="fig"}. ###### Cluster quality using weighted UniFrac community analysis. E09 L09 E10 L10 ---------------------------- --------- --------- --------- --------- Day (dpi) 1.129\* 1.298\* 1.138 1.113\* Irrigation method 1.018 1.057 1.114 1.006 E. coli O157 inoculation 1.002 1.004 1.172\* 1.031 E. coli O157 persistence 0.992 0.967 1.045 1.026 Cluster quality was calculated based on the dissimilarity ratio between/within clusters of samples in a treatment group where a high ratio signifies a distinct cluster. The distance matrices from the weighted UniFrac analysis were used to compute the dissimilarity ratio. \* The highest cluster quality ratio observed in a given planting. ![Leaf age influences the diversity of phyllosphere microbial diversity.\ The Phylogenetic Diversity (PD) of the phyllosphere microbiota from leaves of different ages (dpi). The average ± standard error for all plants the four field trials is shown. n= 73, 84, and 66 for 7, 14, and 21 dpi, respectively; \* P ≤ 0.001 by the Kruskal-Wallis multiple comparisons test. ns: not significant.](pone.0068642.g006){#pone-0068642-g006} ![Phyllosphere microbiota differs due to effects of the day of collection, irrigation, and inoculation of E. coli O157:H7.\ Phyllosphere microbiota identified during the L10 were analyzed by Principal Coordinates Analysis (PCoA) performed on Unifrac distances between bacterial communities collected from plants on different days (A), and for plants at 14 dpi exposed to drip or overhead irrigation (B), the inoculation of E. coli O157:H7 (C), or inoculated plants that were InocPOS or InocNEG (D). Weighted UniFrac distances were used for (A), (C), and (D) and unweighted UniFrac distances were used for (B). The plots are representative of findings for the other field trials and time points. Additional PCoA plots are in [Figure S7](#pone.0068642.s007){ref-type="supplementary-material"}.](pone.0068642.g007){#pone-0068642-g007} To identify irrigation-dependent effects on the microbiota, it was necessary to compare plants collected on the same day. UniFrac distances examined using ANOSIM revealed that the microbiota on sprinkler- and drip-irrigated plants were significantly different from each other for eight out of the 12 time points sampled ([Table 2)](#tab2){ref-type="table"}. The irrigation effects found for one day are shown in [Figure 7B](#pone-0068642-g007){ref-type="fig"}. Although no single genus consistently distinguished the bacterial communities between drip and sprinkler irrigated plants, Xanthomonas was typically more abundant on sprinkler-irrigated plants and Erwinia was enriched on drip-irrigated plants (data not shown). The relative abundance of Leuconostoc and Lactococcus was also higher on drip-irrigated plants, but only for E09 and E10 plantings. ###### ANOSIM cluster analysis of the phyllosphere microbiota between sprinkler- and drip-irrigated Romaine lettuce plants. E09 L09 E10 L10 -------------------- --------- --------- ------------------------------ ------------------------------ --- -------------------------------- ---------------------------------- -------------------------------- ------- ---------------------------------- -------------------------------- -------------------------------- Unweighted UniFrac -0.02 -0.006 0.1 0.13 [\](#ngtab2.1) 0 0.55* [*\\*](#ngtab2.2) 0.22 0.44 [\\](#ngtab2.2) 0.013 0.36 [\\\*](#ngtab2.3) 0.33 [\\](#ngtab2.2) 0.42 [\\](#ngtab2.2) Weighted UniFrac -0.16 -0.068 0.22 [\*](#ngtab2.1) 0.13 [\*](#ngtab2.1) 0 0.12 0.67 [\\\*](#ngtab2.3) 0.44 [\\*](#ngtab2.2) 0.063 -0.029 0.0026 -0.13 The R-statistic is shown for each comparison of clusters of differentially irrigated plants. \ 0.05 \< P ≤ 0.1; \\ 0.01 \< P ≤ 0.05; \\\*P ≤ 0.01 The phyllosphere microbiota differed on plants inoculated with Escherichia coli O157:H7 {#s3.6} ----------------------------------------------------------------------------------------- Inoculation of E. coli O157:H7 altered the phyllosphere to the extent that the lettuce microbiota differed between inoculated and control plants for 10 of the 12 time points examined ([Figure S7](#pone.0068642.s007){ref-type="supplementary-material"}). The result for one of the time points, 14 dpi in L10, is shown in [Figure 7C](#pone-0068642-g007){ref-type="fig"}. Notably, the phyllosphere microbiota recovered from naive (not sprayed) and buffer-only inoculated plants were indistinguishable and differences associated with other factors were more important determinants of the bacterial diversity ([Figure 7C and S8)](#pone-0068642-g007){ref-type="fig"}. Therefore the differences in bacterial inhabitants were most likely due to E. coli O157:H7 and not the 0.1% peptone buffer used to deliver the pathogen onto the lettuce. The bacterial community composition was also distinct between InocPOS and InocNEG plants for nine of the 12 time points sampled, including 14 dpi in L10 ([Figure 7D)](#pone-0068642-g007){ref-type="fig"}. These differences were partially associated with the enrichment of certain bacteria. For example, at 14 dpi in L10, Erwinia was significantly enriched in the phyllosphere of InocNEG plants (P ≤ 0.05) according to the Kruskal-Wallis multiple comparison test. Erwinia was also enriched on InocNEG plants 2.7-fold and 9.2-fold at 14 and 21 dpi in the L09 trial. However, the
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187, 50274, 15, 1992, 2765, 1874, 535, 11773, 31116, 38649, 27, 773, 2993, 457, 84, 4518, 13, 436, 7835, 9559, 13, 533, 703, 310, 28561, 440, 30063, 15, 309, 1599, 352, 457, 84, 644, 14290, 15, 964, 964, 703, 457, 84, 9606, 690, 39276, 37725, 15, 1500, 369, 32943, 323, 5976, 1897, 672, 703, 574, 247, 6255, 19501, 275, 253, 15956, 2270, 84, 1425, 1707, 403, 671, 11307, 326, 4268 ]	type="ref"} Interestingly, our current study demonstrates the induction of protein synthesis after ECC coincides with reduced AMPK activation in tumour‐bearing mice. Furthermore, reduced AMPK activation after a single ECC bout has also recently been observed in castrated mice.[51](#jcsm12271-bib-0051){ref-type="ref"} These findings are in contrast to our previous observations using low‐frequency electrical stimulation and point to the differential regulation of muscle metabolic signalling by different types of contraction. We previously found a sustained AMPK activation following a single bout of low‐frequency concentric contractions in cachectic skeletal muscle.[32](#jcsm12271-bib-0032){ref-type="ref"} The specificity of the responses induced by different types of contractions may be related to metabolic stress as cachectic muscle develops mitochondrial dysfunction.[52](#jcsm12271-bib-0052){ref-type="ref"}, [53](#jcsm12271-bib-0053){ref-type="ref"}, [54](#jcsm12271-bib-0054){ref-type="ref"} The cachectic muscle\'s anabolic and metabolic response to different contraction types will require further investigation. Nonetheless, our findings suggest that ECC may be a potential therapeutic treatment to promote muscle anabolism during cancer cachexia progression. Muscle signalling related to inflammation, energy status, and proteostasis are disrupted during cachexia progression and have been implicated in the regulation of muscle wasting.[55](#jcsm12271-bib-0055){ref-type="ref"}, [56](#jcsm12271-bib-0056){ref-type="ref"} Interestingly, many of these same pathways are induced by muscle contraction and exercise.[57](#jcsm12271-bib-0057){ref-type="ref"} IL‐6 and muscle STAT3 signalling through the gp130 receptor are activated during the progression of cachexia[30](#jcsm12271-bib-0030){ref-type="ref"}, [52](#jcsm12271-bib-0052){ref-type="ref"}, [58](#jcsm12271-bib-0058){ref-type="ref"} and are associated with mTORC1 and protein suppression in pre‐clinical cachexia models.[7](#jcsm12271-bib-0007){ref-type="ref"}, [28](#jcsm12271-bib-0028){ref-type="ref"} Inhibition of muscle IL‐6 signalling through either direct STAT3 inhibition or gp130 loss can attenuate wasting in mouse models of cachexia.[30](#jcsm12271-bib-0030){ref-type="ref"}, [31](#jcsm12271-bib-0031){ref-type="ref"} We have previously found that short‐term PDTC treatment attenuated the suppression of mTORC1 signalling and protein synthesis while concomitantly reducing muscle STAT3 and NFκB activation in Apc ^Min/+^ mice.[29](#jcsm12271-bib-0029){ref-type="ref"}, [32](#jcsm12271-bib-0032){ref-type="ref"} We extend these findings by demonstrating a single PDTC dose improved basal protein synthesis. It has recently been suggested that intermittent cycles of pathway inhibition/activation may be required to combat muscle wasting during cancer cachexia.[59](#jcsm12271-bib-0059){ref-type="ref"} Indeed, many cytokine‐related signalling pathways have established roles in myogenesis[60](#jcsm12271-bib-0060){ref-type="ref"} and load‐induced muscle growth and remodelling.[41](#jcsm12271-bib-0041){ref-type="ref"}, [42](#jcsm12271-bib-0042){ref-type="ref"}, [61](#jcsm12271-bib-0061){ref-type="ref"} Therefore, we utilized an experimental paradigm that lowered chronic muscle inflammatory signalling but did not block contraction‐induced signalling.[32](#jcsm12271-bib-0032){ref-type="ref"} Importantly, we found that PDTC treatment increased both basal and ECC‐induced protein synthesis in cachectic muscle. These findings demonstrate that cachectic muscle retains the anabolic capacity to increase protein synthesis, and inflammatory signalling contributes to the suppression of these processes. Additional research is warranted to determine the specific mechanisms related to STAT3 and NFκB that serve to diminish the capacity for protein synthesis in cachectic muscle. Moreover, further research is also required to determine the effect of muscle inflammatory signalling on metabolic remodelling in response to repeated contraction bouts, which could dramatically impact health outcomes related to exercise. Conclusions {#jcsm12271-sec-0023} ----------- In summary, we examined cachectic muscle\'s ability to induce protein synthesis in response to ECC and determined the role of muscle inflammatory signalling involving STAT3 and NFκB on ECC‐induced anabolic signalling. We found that mechano‐sensitive signalling pathways related to P38, ERK1/2, and Akt were not altered by the cachectic environment in wasting muscle. While cachexia did not attenuate the ECC induction of mTORC1 signalling, the capacity for protein synthesis remained suppressed compared with healthy controls. Interestingly, we found that reducing muscle STAT3/NFκB signalling improved basal and ECC‐induced protein synthesis during severe cachexia. These studies demonstrate that mechano‐sensitive signalling pathways are maintained in skeletal muscle, but STAT3/NFκB signalling serves to attenuate basal and ECC‐induced protein synthesis. Further work is necessary to determine whether intermittent anti‐inflammatory therapies combined with exercise training may be useful to alleviate suppressed muscle protein synthesis during cancer cachexia. Conflict of interest {#jcsm12271-sec-0026} ==================== Justin P. Hardee, Brittany R. Counts, Song Gao, Brandon N. VanderVeen, Dennis K. Fix, Ho‐Jin Koh,, and James A. Carson declare that they have no conflict of interest. The authors thank Gaye Christmus and Dr Bradley Gordon for editorial review of the manuscript. This work was supported by National Institutes of Health \[grants R01 CA‐121249 (National Cancer Institute) and P20 RR‐017698 (National Institute of General Medical Science)\] to J.A.C, SPARC Graduate Research Grant from the Office of the Vice President for Research at the University of South Carolina to J.P.H and an ACSM Foundation Research Grant from the American College of Sports Medicine Foundation to J.P.H. The authors certify that they comply with the ethical guidelines for authorship and publishing of the Journal of Cachexia, Sarcopenia and Muscle.[62](#jcsm12271-bib-0062){ref-type="ref"} Q: Split duplicates in lists using LINQ So far I have this code public class Card { public int suitID; public int cardValue; } public class DeckManager { private List<List<Card>> FindCardsPerSuit(List<Card> cards) { var _cardsCombination = cards .GroupBy(x => x.cardValue) .Where(g => g.Count() > 2) .Select(c => c.ToList()) .ToList(); return _cardsCombination; } } I'm working on a Rummy card game and what I'm trying to do is to find if the combination of cards that the player want to play is valid or not. When the player selects some cards from the hand, I need to check if the cards with the same value have a unique suit, otherwise, add it to a new list. Example: The player has 8 cards all with the same value but different suits, the min combination is 4 so you can do 2 combinations, and because you play with 2 decks you have 2 cards per suit. How can I find out if I want to create a list of lists of combinations? At the moment the _cardsCombination query gets all the cards selected and make a smaller group with all the cards with the same value. How can I do the same thing and create subgroups for each card with suit duplicate? Thank you. A: var _cardsCombination = cards .GroupBy(x => x.cardValue) .SelectMany(g => { // group cards by suit var cardsPerSuit = g.GroupBy(c => c.suitId); // max number of cards with same suit (will be 1 or 2 for two decks) // this will be number of subsets var maxCardsPerSuit = cardsPerSuit.Max(gg => gg.Count()); return Enumerable // create subset for each setNumber from 0 to maxCardsPerSuit - 1 .Range(0, maxCardsPerSuit) .Select(setNumber => cardsPerSuit // take nth card from each suit .Select(s => s.ElementAtOrDefault(setNumber)) // skip nulls .Where(s => s != null) ); }) .Where(g => g.Count() > 2) .Select(c => c.ToList()) .ToList(); McConnell Aid: “She’s clearly, this sounds extreme, but she is emotionally unbalanced. I mean it’s been documented. . . she’s suffered some suicidal tendencies. She was hospitalized for 42 days when she had a mental breakdown in the ’90s.” There are also allegations that Jud
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871, 309, 1353, 417, 10412, 670, 1142, 273, 253, 5239, 326, 5037, 83, 1316, 4197, 689, 253, 1107, 15, 187, 187, 3220, 3367, 5037, 83, 1316, 30740, 403, 12459, 285, 12210, 15, 14820, 13, 13402 ]	answer special about the virus, spending most of his time talking about the way America could use the crisis to enact their leftist energy policies. Biden recalled the Great Depression, noting former President Franklin Roosevelt used that crisis to enact dramatic government programs, something he also wanted to do. “It’s like the New Deal,” he said. “Think of every great act that — every great change that has taken place. It’s come out of a crisis.” Biden proposed a similar dramatic surge in government spending for green energy infrastructure, including 550,000 charging stations for electric cars, windmills and solar panels, as well as spending for better battery technology. Biden said the coronavirus crisis would lead the American people to recognize the need for change, especially for workers and Americans suffering the effects of “systemic racism.” “It’s like the Band-Aid has been ripped off,” Biden said. The former vice president’s hat-tip to the Green New Deal comes as prominent leftist Rep. Alexandria Ocasio-Cortez has criticized his climate change platform. “I don’t think that the vice president has a climate change policy that is sufficient right now,” Ocasio-Cortez said in a recent interview.What others say: I just want to thank you again for representing me. You have provided so much for the kids and me that I could not properly put into words. I can say that I have a new measure of freedom, safety, boundaries, strength and peace that prior to meeting you I did not have. Thank you for standing firm for me when no one else would and when I didn't know how to. -- J.U., Marysville,WA In a time that was very difficult and painful, Paul worked on my behalf and for my children. He took charge, fought for us and steered us through. He did this in a way that caused us to feel safe in the midst of turmoil. I will be forever thankful for his expertise and his kindness. -- C.B., Bellevue, WA I have worked with other attorneys before and I have to say that my experience with Mr. Petry was the best. He really took good care of my case, made me aware of my options, and went above and beyond to help not only provide counsel, care and concern for me, but worked his best to achieve the best outcome between the different parties' grievances. Without any reservations, I recommend Paul Petry to anyone seeking legal counsel and advice.-- A.A., Seattle, WA Paul Petry was very professional, encouraging and supportive during my painful divorce, while also highly skilled at reaching a fair settlement in a short amount of time, though never rushing my divorce to finality. He kept my legal costs to a minimum and did not try to lengthen his services with unnecessary meetings. I noticed he worked very well with others in the legal community, yet maintained my interests as his first priority without negativity toward my ex-husband or his legal counsel. Throughout the process, Paul consistently advised me of options to consider in order to protect my emotional, financial and legal well-being.-- I.H., Issaquah, WAQ: ASP.NET Core 2.1 - Stack overflow exception related to dependency injection I'm getting a stack overflow exception after I load 4 or 5 times a simple controller action. The web app is running on Azure and I was able to dump the exception information and the problem seems to be related to Dependency Injection. internal object GetService(Type serviceType, ServiceProviderEngineScope serviceProviderEngineScope) { if (_disposed) { ThrowHelper.ThrowObjectDisposedException(); --> this is executed } var realizedService = RealizedServices.GetOrAdd(serviceType, _createServiceAccessor); _callback?.OnResolve(serviceType, serviceProviderEngineScope); return realizedService.Invoke(serviceProviderEngineScope); } Running the web app in my computer has no issues, it only fails in PROD. This is how I captured the exception in Azure: https://blogs.msdn.microsoft.com/benjaminperkins/2017/06/28/capture-a-stackoverflowexception-and-make-a-dump-0xc00000fd/ I opened the dump in Visual Studio and I could identify the code line where it failed (described above) but I still don't know how to fix it. All my dependencies are resolved with 'scope' lifetime. Any help is appreciated. A: I finally fixed it! I had a class that had like 20 dependencies and each dependency had more dependencies, maybe 4 or 5 level. There were no circular dependencies because this was working fine in my development environment. After I did a refactoring and reduced the dependencies, it worked out fine. Because it was working fine in my development environment but not in Azure App Service, I assume there's some limitation on the dependency instances or levels you can define when the app is hosted in Azure. This was my methodology to fix it: 1) Find the simplest case that fails. 2) Comment out all the depedencies and try again. It worked, ok, it's about dependencies. 3) Dump the stack overflow exception in production as this error didn't occur in the dev environment. 4) Confirm it's a dependency injection issue and examine .NET Core source code. 5) Reduce dependency instances and levels. 6) Deploy. If it doesn't work, go to (5). If it works, you are happy again :) Our Top 5 Instagram Tips for 2019 Instagram is quickly becoming a go-to platform for businesses across the United States and Scottsdale-based the spr agency, an award-winning social media and public relations agency, has released its top 5 tips for succeeding on the platform in 2019. Be Authentic The rush to capitalize on the popularity of any social media platform may also bring snap decisions on just what a company should post. Many companies chase trends instead of setting them. “While it’s easy to duplicate what others in your industry or vertical are doing, it’s more important to be authentic and true to your brand,” said Al Stevens, president and founder of the spr agency. “Social media users know when you’re phoning it in. They know when you’re not being yourself. And with all marketing, it’s important to speak authentically and provide a unique perspective.” Be Creative While authenticity is a must, it’s also important to be creative in your approach. “Given the number of Instagram posts that hit the platform’s news feed each day, Instagram users want to see originality and the spark of creativity,” said Christy Stevens, vice president of the spr agency. “They’re looking for posts that will inspire and entertain them. That’s what they choose to engage with when they double-tap a photo.” Great Photography Makes Great Content Investing in quality images is a must on any social media platform but it’s key to engaging Instagram users. There is a direct correlation between great photography and high engagement on Instagram. “Think of what inspires you and what will inspire your customers,” Al Stevens said. “If you’re not excited by the image you choose, how will your customers and followers be? You have to believe in each image and be willing to defend your job with the photo selection you make. It’s that important.” Hashtags Matter Thinking about throwing a few hashtags on that Instagram post? Don’t – at least not without researching the hashtags that best fit your post and your brand. “Hashtags for the sake of hashtags is definitely not a successful strategy,” Christy Stevens said. “It’s important to select hashtags that will help your post build a successful base and launch it into a higher sphere of influence.” Don’t Forget the Video While still images are the primary way of succeeding on Instagram, it’s important to branch out into the company’s other posting avenues – Instagram Stories and IGTV. Both video products have gained traction over the past 18 months and are expected to continue to gain market share against Instagram’s original still imagery news feed. Instagram Stories quickly outpaced Snapchat upon their launch and the allure of IGTV for videographers stems from its freeform use of video – with no time limits set by Instagram. For more information about the spr agency, please visit www.thespragency.com or call (480) 648-1770.Pages Tuesday, May 15, 2012 Biggest bust/improvement: Donruss Hey! It's Harold Reynolds again! This is not a repeat. This is post number 2,001. I republished this card both as a reminder to enter the contest and as a lead-in to my next judging fiesta, namely, figuring out the biggest improvement and bust in the history of Donruss. I don't think Donruss has as avid a following as the previous two brands we've compared, Topps and Upper Deck. I know I'm not crazy about many of the sets that Donruss produced over the years. My personal Donruss favorites are 1984 and 1985. Plus, 1981
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3006, 253, 2934, 273, 247, 8845, 9974, 15, 187, 187, 510, 2852, 273, 253, 28054, 3570, 4866, 187, 187, 36, 13780, 14, 746, 310, 247, 1786, 8891, 273, 19876, 22260, 13, 285, 697, 2538, 327, 253, 46098, 3114, 452, 644, 25205, 275, 4088, 326, 954, 7108, 588, 1620, 2793, 15, 2058, 253, 1072, 673, 13, 253, 26296, 556, 4197, 9091, 281, 31551, 907, 285, 5485, 253, 3369, 281, 16072, 670 ]	fare for accelerating technoculture & screaming memes, with a side order of strangeness and charm. Read articles and interviews which illuminate the New Edge culture. Warning:This site may contain unlabelled irreverence and subtle playfulness.Humorless and hypersensitive people should proceed with caution.TOMORROW'S TECHNOLOGY TODAY: Cell phones For the most part your cell phones do all the work...making calls, sending text messages, taking pictures. In Tomorrow's Technology Today Matt Stone shows us that the phone case is now being used to do some pretty cool stuff too.These are sound effects I have recorded for different projects that I am giving away. Check back as I add to the page often. Click on the description to download. I cannot predict your browser configuation so this will either make a page with a player or ask you where to save it. If it makes a player, right-click and choose "Save As... instead"A procession of 60 cars honking their horns and brandishing signs proclaiming “Free Them All” circled Bergen County Jail in Hackensack, New Jersey on March 27. A prisoner and guard in the jail had just tested positive for COVID-19, and the protesters were demanding that all nonviolent incarcerated people and ICE detainees be released in order to stop the spread of the virus and save thousands of lives. The protesters called it a “drive-by protest.” Since late March, similar actions involving hundreds of cars have taken place in other states as well, including Louisiana, Illinois and North Carolina. The protests are just one of the many creative tactics that organizers have been employing to show solidarity with the immigrant community while social distancing. Ambien Mitchell is an activist and educator working at New Sanctuary Coalition, a clinic that provides legal and emotional support for people navigating the immigration system. In her view, it has never been more critical to advocate for humane policy and demand accountability for those in power. “We’re living in a system of state violence, with decades of experience perpetuating incredible cruelty on vulnerable populations,” Mitchell said. “The state has already proven to have a blatant disregard for human life. And they’ve already proven that they believe some lives are less valuable than others.” “Every prison and every detention center is like a cruise ship that’s not allowed to dock.” Although the entire nation is grappling with the COVID-19 pandemic and its consquences, the undocumented community has been facing unique — and often overlooked — struggles. Those imprisoned in detention centers are kept in close quarters where social distancing is impossible. Economic relief plans such as the CARES Act neglect undocumented people altogether, though many undocumented workers are providing essential labor during this crisis and most undocumented people pay taxes. Meanwhile, despite the federal government’s own admission that the best thing that can be done to flatten the curve is to limit travel, deportations and ICE raids are still taking place. “It’s no secret that the undocumented community has been targeted and criminalized for decades,” said undocumented organizer Li Adorno, who works with the New Jersey chapter of the immigrant rights group Movimiento Cosecha. “Even in a crisis, the undocumented community is still being targeted. We’re always the ones that the government forgets about.” ‘Free them all’ Kathy O’Leary is the region coordinator for New Jersey at Pax Christi USA, a national Catholic peace and justice organization. In the past, she has helped compile reports on the desperate conditions plaguing New Jersey jails. Since the quarantine began, O’Leary has been pouring her energy into the fight for ICE detainees and prisoners to be released. In addition to organizing drive-by protests of detention centers in New Jersey, she’s also helped draft a petition calling on Gov. Phil Murphy to use his emergency powers to take action. “On a good day, getting access to health care when you’re in prison is completely at the mercy of the administration,” O’Leary said. “And a jail is not a sealed environment. Even though they cut off visitation, the guards still rotate three times a day and then go home to their families. The guards could very easily bring the virus back to the jail without knowing it — and if there is an outbreak in the jail, then that gets brought back to the community.” The petition is backed by over 30 social justice and immigrant rights organizations with chapters in New Jersey, including the Jewish Coalition for Refugees, the Sunrise Movement and Cosecha. “Even if all the petition does is elevate the issue — that’s important too,” O’Leary said. She considers the petition an opportunity to stand with incarcerated people across New Jersey who are going on hunger strike, demanding access to essentials like gloves, masks, soap and hand sanitizer. Skipping even a single meal in the dining hall of a detention center comes with the risk of being thrown in solitary confinement. Holding ICE accountable for their failures According to Ambien Mitchell of New Sanctuary Coalition, phone calls are another simple and remote option when it comes to advocating for undocumented people during the crisis. She suggests calling elected representatives because they can pressure ICE, as well as calling ICE field agents and detention centers themselves. “Every prison and every detention center is like a cruise ship that’s not allowed to dock,” Mitchell said. “And at this point, inaction has become an incredibly brutal and violent action. These aren’t fun conversations, but they’re conversations that are worth having — ICE is a federal agency, and we do pay their salaries with our tax dollars.” Adorno believes that ICE’s unwillingness to cease operations is not only putting detainees at risk, but the community at large. “Even during the pandemic, ICE continues to hunt down undocumented community members,” Adorno said. “In the past, ICE has claimed they would not go to school zones and courts — but then went against their own memos. That’s why the immigrant and undocumented community has very little faith in the local or federal government.” The impact of this mistrust is that even if they are experiencing symptoms, many undocumented people may hesitate to go to a hospital, despite ICE’s claim that they will not be arresting people who are seeking medical care. “Undocumented people don’t have health insurance, and they’re afraid to seek care at hospitals because ICE might go there,” Adorno said. “If you only have one member of the family who is working right now, and they get arrested, how is that going to impact the rest of their family?” Campaigns for commissary and worker relief First Friends is an organization of people who visit detained immigrants and asylum seekers in New York and New Jersey. Because of the crisis, their volunteers can no longer visit detention centers — so the organization has started a Gofundme to raise commissary money. Often, detainees can’t afford to buy the basics due to marked up prices and meager salaries that border on slave wages. “Commissary can be used to help incarcerated people feel a little more comfortable during this stressful time,” O’Leary said. “Buying an extra pack of ramen noodles or a candy bar can make them feel more human. But there are other things in there too — like soap and shampoo.” She noted that while inmates in places like New York are being used to produce thousands of gallons of hand sanitizer for less than a dollar an hour, they are not allowed to purchase sanitizer themselves because of the alcohol content. O’Leary also added that in addition to buying hygiene products, the crowdfunded commissary can also be used for phone calls to family, lawyers and friends — crucial connections to the outside world in a time when many inmates are lonelier and more isolated than ever. Also organizing to respond to financial need is Cosecha, a coalition of undocumented people and allies who have previously won fights like driver’s licenses for all in New Jersey. “Undocumented communities have always joined together to surpass tough times like this,” Adorno said, who is currently quarantined with Cosecha members and developing strategies for relief. “In our home countries, we don’t have a lot of help. The mutual aid we’re seeing rise up — this is the kind of thing that the undocumented community thrives at. We’re good at this because we’ve had to do it in the past. Nobody else is going to come rescue us.” Since the pandemic began, immigrants rights groups like Cosecha have been mobilizing to create relief funds for the undocumented community. (WNV/Loretta Graceffo) Because of their legal status, undocumented workers don’t have access to necessities like health insurance, paid sick leave, unemployment and other forms of government relief. In order to help ease the burden, Cosecha has started a fund to help families with needs like food, rent and utilities during the crisis. “You can’t feed a movement with service,” Adorno said. “You have to feed a movement by bringing people together. This fund has to be accompanied by organizing efforts. Otherwise it’s going to be really hard to sustain it.” Since the pandemic, Cosecha has begun training organizers through video conferences — and shifted its focus towards pushing for economic measures that will elevate undocumented and working class people, like popularizing the idea of a rent strike. The future of the immigrant rights movement COVID-19 is a health crisis of epic proportions, and its effects on the undocumented community have been devastating in ways that most Americans will never experience. At the same time, the pandemic has produced opportunities to mobilize and opened the door to conversations about
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30794, 275, 894, 13042, 366, 369, 4398, 740, 7739, 380, 2462, 8887, 4398, 1458, 6, 5936, 326, 7235, 14523, 390, 14314, 432, 894, 13042, 366, 4315, 310, 22879, 275, 253, 6981, 15, 187, 187, 5817, 3930, 998, 1430, 187, 187, 35484, 5482, 273, 8728, 59, 19568, 285, 4110, 497, 10141, 323, 2159, 14, 3945, 7882 ]	app1-cancers-10-00031){ref-type="app"}. 3.13. Statistical Analysis {#sec3dot13-cancers-10-00031} -------------------------- Statistical differences between controls and drug-treated cells were determined by one-way ANOVA (Sidak). p-values \< 0.05 were considered statistically significant. Data were analyzed using the Stata 8.2/SE package (StataCorp LP, College Station, TX, USA). 4. Conclusions {#sec4-cancers-10-00031} ============== It is well established that drug tolerance is one of the key challenges for dual PI3K--mTOR inhibitors as NVP-BEZ235, which explains the slow progress of research and development of these inhibitors. Currently, only eleven new dual PI3K--mTOR inhibitors, including NVP-BEZ235, are being evaluated actively in the clinical stage, is currently in phase I/II clinical trials for advanced solid tumors (ClinicaTrials.gov, U.S. National Institutes of Health, Bethesda, MD, USA: <http://clinicaltrials.gov>), but none has been approved by the FDA. Although significant therapeutic effects against cancer have been demonstrated, NVP-BEZ235 have shown significant toxicity, including stomatitis, noninfectious pneumonitis, rash, hyperglycemia, and immunosuppression. Encapsulation strategy offers a potential approach for enhancing the solubility of NVP-BEZ235 improving its bioavailability and suggests the potential use of this formulation for oral administration. Oral administration would allow outpatient treatment, improving quality of life and reducing treatment costs. Cytosolic delivery strategies could contribute to simplify the entry or export of various cargo that are insufficiently permeable to plasma membrane. In this work we proposed an engineered system, based on CaCO~3~, to deliver NVP-BEZ235. Because of their central role in the initiation and progression of tumors, blockade of the mTOR and PI3K signaling pathways has emerged as a compelling target for the development of novel drug formulations for maximal therapeutic efficacy in many tumors. Taken together, it appears that dual PI3K/mTOR inhibitors, such as NVP-BEZ235, are required. Because of its intrinsic chemical hydrophobicity, NVP-BEZ235 is poorly tolerable from patients and negatively influenced the clinical studies \[[@B27-cancers-10-00031]\]. Its toxicity profile causes high percentage of adverse events leading to frequent discontinuation treatments. Despite these problems NVP-BEZ235 remains an attractive agent. Therefore, in order to overcome its chemical limitations, it is necessary to either reduce the administered dose or combining the efficacy of this molecule with other drugs for a synergic action. In view of its potentiality, and on the other side of its limitations, we focused this work on finding a nanotechnological strategy to achieve higher efficacy of the drug toward cancer cells, decreasing drug concentration and increasing drug penetration. Hence, we developed at first a promising payload drug delivery system based on CaCO~3~ NCs that improved the water solubility of NVP-BEZ235 making it immediately available to cell machinery. Furthermore, a new highly sensitive analytical method methods have been used to determine, qualitatively or quantitatively, whether NVP-BEZ235 has successfully traversed the cell membrane. The obtained nano-formulation has a cytosolic localization more efficient (almost 30%) than the free drug as demonstrated in the quantification analysis of NVP-BEZ235 in the intracellular fraction. This result is affected in a cytotoxic effect almost 50 times higher than free drug at the same nominal concentration, in T-cell lymphoma line, as well as in the phosphorylation of proteins involved in the mTOR pathway, as demonstrated in the western blot analysis. These overall results show that the fabrication of loaded NVP-BEZ235 CaCO~3~ nanocrystals is a promising drug delivery system able to improve the pharmacokinetics of this drug. Progetto "Tecnologie Abilitanti per Produzioni Agroalimentari Sicure e Sostenibili" (T.A.P.A.S.S)---"Cluster Tecnologici Regionali 2014". Codice regionale progetto PELM994 (CUP B38C14002040008). "FuturelnResearch" APQ Ricerca Regione Puglia---Programma regionale a sostegno della specializzazione intelligente e della sostenibilità sociale ed ambientale. PRIN 2010--2011 (D.M. 1152/ric del 27/12/2011) Nanotecnologie molecolari per il rilascio controllato di farmaci/NANO Molecular tEchnologies for Drug delivery NANOMED prot. 2010FPTBSH, CUP: F81J12000380001 is gratefully acknowledged. Viviana Vergaro and Giuseppe Ciccarella conceived and designed the experiments; Monica Civallero and Maria Cosenza performed the biological experiments; Francesca Baldassarre analyzed all data experiments with statistical analysis; Cinzia Citti and Giuseppe Cannazza performed LC-MS/MS experiments and contributed to results and discussions; Francesco Paolo Fanizzi, Stefano Sacchi and Samantha Pozzi provided the reagents and materials and contributed to results and discussions. Viviana Vergaro and Monica Civallero wrote the paper. The authors declare no conflicts of interest. • Detection and quantification limits (sensitivity) Limit of quantification (LOQ) was defined as the concentration at which the quantifier transition of BEZ235 yielded a signal to noise ratio (S/N) of 10 and it was 1 μM in cell lysate. Limit of detection (LOD) in cell lysate was estimate based on 5:1 S/N and it was 0.5 μM. • Specificity Typical SRM chromatograms of BEZ235 and IS in cell lysate showed no interfering peaks from endogenous substances at the retention time of BEZ235 and IS. The chromatograms of blank cell lysate also had no interfering peaks at the retention times of BEZ235 and IS. The specificity results indicate that the method is highly selective for BEZ235 analysis. • Calibration curve and Linearity Calibration curves for BEZ235 were performed in cell lysates (1 to 100 μM). Five replicates were used to establish the linear calibration equation (y = mx + c) and analyzed using the ratio of analyte peak area over IS peak area after quantitative integration by Mass Hunter software. Linearity was measured as the coefficient of determination (R2) for five calibration replicates. The acceptance criteria for each back-calculated standard concentration were ±15% deviation from the nominal value except at LOQ, which was set at ±20%. Linearity was excellent in the range 1--100 μM with corresponding coefficient of determination R2 \> 0.998. • Accuracy and precision Intra-day accuracy and precision were assessed from five replicates of LOQ and QC concentration levels (low LQC, middle MQC and high HQC). Inter-day accuracy and precision were assessed on three triplicates for five-day analysis of the three QC concentration levels. Accuracy of the method was calculated as percent deviation based on the difference between the mean concentration found and the nominal concentration. The percent deviation should be within 15% of the actual value, except at the LOQ, where it should not deviate by more than 20%. Precision was evaluated as percentage coefficient of variation (%CV) of the mean concentration found. The precision determined at each concentration level should not exceed 15% of the CV, except for the LOQ, where it should not exceed 20% of the CV. The accuracy and precision data for cell lysate. The intra-day accuracy showed percent deviation ranging from −1.19 to 4.22% with a %CV from 0.88 to 4.65%. The inter-day accuracy and precision showed percent of deviation ranged from to −3.80 to 8.50% with a %CV from 2.09 to 8.78. Since the accuracy and precision values were found within the acceptance limits, these results suggested that the method is accurate and precise. • Recovery The extraction recovery of BEZ235 was determined at the LQC, MQC and HQC levels by comparing the peak areas of BEZ235 extracted from spiked cell lysate samples prepared by spiking BEZ235 in blank cell lysate with the corresponding concentration of authentic standard solutions. Experiments were performed in five replicates. The extent of recovery should be consistent, precise and reproducible. The recovery of extraction of BEZ235 from cell lysate was \>82%. • Matrix effect The matrix effect was evaluated by determining the matrix factor (MF) and the IS-normalized MF from cell lysate. The determination was performed at the LQC, MQC and HQC levels in triplicate. The MF of BEZ235 was calculated by comparing the peak area of BEZ235 extracted from samples prepared by spiking BEZ235 in cell lysate with the corresponding concentration of the authentic solution of BEZ235 prepared in mobile phase. The MF of IS was determined and calculated in a similar manner. The IS-normalized MF is the ratio between the MF of BEZ235 and that of IS. The %CV of the IS-normalized MF from blank cell lysate should not exceed 15%. The %CV of IS-normalized MF in cell lysate was \<10%. The %CV \< 15% suggests that ion suppression or enhancement from cell lysate matrix is negligible in the assay. • Stability Stock solutions of BEZ235 and IS were checked for short-term stability
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quickly before continuing. "As I said, a few of these human people had advanced capability, they were natural channels. I am sure had they been T'Iea then they would have been quickly taken up and sent to Ter'Hadsnefel to learn how to temper and control their natural ability, taught the arts and ways of our T'Iea mages. To leave them untrained would have been dangerous, both to themselves and to others. Stories abound of such humans destroying great swathes of the land either by miss use of the arcane or by un-tempered ability. As a result many who exhibited these traits, if discovered, where cast out to live solitary lives far from others of their kind, for the humans had a deep mistrust of them. Some of these unfortunate people were even ritually burned if they were thought to have misused their traits and un-tempered skill. Anyway, many of us were assigned to stay amongst these humans and help where we could. But Te'Onolan'u'De'Hu'uinned increasingly demanded restraint. Some of us helped more than we should perhaps, for his orders were not to interfere. " As before Orln turned and gazed at Neth'Gore's back for a few seconds. Thor waited for Neth'Gore to say something for it seemed that Orln was inviting him to do so, but the mage remained with his back turned to them, toying with his gear. Orln carried on with his explanation. "On returning from one such trip we learnt that the goblins had invaded our encampment, probably looking for food or an opportunity to thieve anything that they thought useful, or so we were told by others in the legion. The goblins were easily held off and sent running, for they were not many, and their attack was disorganised and uncoordinated with no real strategy or pre-planning. But Te'Onolan'u'De'Hu'uinned seemed to bare a strange hatred towards them and he ordered his guards to pursue the goblins, hunt them down and kill them. He said this would act as a deterrent to others. We were appalled to hear such an order for that is not our way of course. My understanding was that we should lay low and explore, our orders were to watch for T'Iea'Neat'Thegoran activity not to take grim revenge upon a lesser race. Over the next few months, Te'Onolan'u'De'Hu'uinned seemed to change, his attitude grew more grave. He became insular, guarded and thoughtful, quick to anger. He ordered small unprovoked skirmishes into the goblin lands to attack their encampments and destroy the goblin infrastructure, burning any encampments that were found, hunting them down and killing them even fowling water sources known to be used by them. Many in the legion could not understand this, many sought to dissuade the command chain of the legion. Those that felt this way became organised and approached Te'Onolan'u'De'Hu'uinned in an attempt to discover why he felt such hatred for the goblins, alas these soldiers we never saw again. We were told they had been killed in a skirmish. But this we did not believe for the goblins were disorganised and had primitive weapons and little skill in wielding what they had, they could not overcome the skill of our soldiers unless by pure luck they overcame an individual by sheer numbers. So the persecution of the Goblin men continued. We knew this was not the way of the T'Iea legions, never have we sought to be such an aggressor, especially upon a far weaker force. We couldn't believe that soldiers we knew so well could break that code of training and reduce themselves to such actions. But because of this systematic policy of genocide the goblin men learnt to fear and hate us. One day Te'Onolan'u'De'Hu'uinned announced that his sources had discovered what he thought to be the main centre of population of the goblin men, he was planning an all-out attack to teach them a lesson, "once and for all we will settle the goblin problem," he said. We were deeply shocked and many complained to Te'Onolan'u'De'Hu'uinned that this was not what we had been sent here for. Te'Onolan'u'De'Hu'uinned flew into a rage; he ordered the imprisonment of many that he saw opposing him. One such was the swordsman of our Trete'Y'Thego, he was taken from us and we have not seen him since. The raid on the goblins went ahead." Here Orln lowered his head into his hands and sighed, "it was inevitable, the goblin forces were wiped out, but not content with his victory, Te'Onolan'u'De'Hu'uinned ordered the complete burning of all the lands surrounding the encampment and the systematic murder of all goblins found. Both I and Neth'Gore were sickened to the core at this despicable act. We would have no part in it for it is one thing to fight another armed warrior, but quite a different thing to kill in cold blood the elderly and the innocent, the females and their whelps." Thor could not believe what he was hearing; this was not something that he expected. The T'Iea legions had strict codes of honour and behaviour towards the enemy forces and especially towards the innocent and to civilians. To break these codes would be unimaginable, a heinous crime against the oppressed but also against the legion itself. The expression upon his face must have given him away for Orln then said, "I see by your face that you are abhorred with this story. Then perhaps you would have done the same as myself and Neth'Gore and others. We deserted, we returned back to Ter'Hadsnefel, we gave ourselves up as deserters and we told our story in the court of the generals. Well to cut a long story short, we were divested of our rank and denied any further active duty in the legion whilst our final fate was decided. But thank the Maker, to our honour one general was on our side he fought for our case and even though he did not change the final verdict of dishonourable dismissal from the ranks he did manage to keep us from imprisonment and take on responsibility for us. That general even though he risked much, made sure that we remained trained and able minded over the period of time we were with him. We do not know even today why he took this action. But we are thankful to him for his mercy." Thor thought for a while and said, "that general, the one who showed you mercy, I guess that he was The lady Solin's friend, Te'Onolan'u'De'Yiun?" "Yes," was the simple answer. Thor just nodded slowly in response. "Alright gentlemen, I thank you for your frankness and trust. It is a sorry tale with more than a few surprises. I do not know what we may find there in the east, but we are tasked with this and I intend that we carry out our orders to the best of our capability. We leave in the morning, I suggest you say your farewells and make good any outstanding business. We have a long journey ahead of us, as you well know. I will be grateful for your knowledge and experience to get us to our destination swiftly and safely." ## Chapter 18. First Class to Gwéldølĩn That evening Nar'Allia found herself walking through the wide streets of Scienocropolis. She was being escorted to the airship that was waiting to transport the Pnook emissary and herself to Gwéldølĩn. She found herself travelling through a very prosperous looking part of the Pnook city accompanied by two Pnook guards, a personal escort of honour sent by the Pnook King himself. She looked up at the buildings that surrounded her. Tall, angular edifices, reaching high enough to scrape the sky, if she looked upwards for too long she found herself experiencing a sensation of falling, of losing her balance, it seemed like the building were tilting over above her, almost falling over to crush her. She shook her head. She wondered at the buildings being pointed out to her by the two escorts, the various purposes and uses to which they adhered, many of which Nar'Allia did not understand. Nar'Allia was in no doubt that the city may appear beautiful to some, in deed she could see herself that it possessed a certain attraction, yet it was so very different from her home. T'Iea cities had an architectural emphasis linked to the natural world, an organic component that defined their character. But here, there was nothing natural; it was totally a creation of the Pnook, without any naturalistic component whatsoever. But then the Rust Desert did not offer much in the way of natural beauty, at least not as she would describe. She had to admit she did find this a little unsettling. The buildings perhaps did have a certain beauty about them yet she found them also to be hard and sterile. As she walked her mind wandered, she found her curiosity rising within her as to whom this emissary of the King may be, she had neither met the King or his emissary as yet. Her escorts had been sent with a sealed note. She
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26542, 253, 2442, 323, 5237, 281, 7117, 3417, 275, 253, 2362, 326, 12254, 8, 3733, 18418, 4035, 15, 12601, 1375, 13, 5749, 85, 62, 248, 2471, 273, 1014, 247, 2014, 3558, 273, 271, 31281, 3417, 6125, 21388, 36730, 5237, 1580, 352, 734, 453, 373, 342, 19050, 9091, 285, 35580, 6380, 2144, 275, 247, 48245, 3320, 6363, 449, 187, 38421, 12027 ]	on two allegations of Defendants' violation of the ESA's consultation requirements. First, Plaintiffs argue that the biological opinion relied upon by Defendants in conducting their training exercises was issued to Defendants by the United States Fish and Wildlife Service ("FWS") without Defendants having first submitted to the FWS the required biological assessment. Before delving into this claim, the Court shall address the standard to be applied to the FWS' issuance of the biological opinion. Defendants allege that Plaintiffs failed to comply with the ESA's requirement that a Plaintiff provide Defendants with notice of suit 60 days before filing. Plaintiffs counter with the letter that they sent informing Defendants of their intent to sue based on Defendants' failure to prepare a biological assessment for the FWS. Because the Court finds, at least at this stage, that Plaintiffs complied with the notice requirement, the appropriate standard to apply is whether there has been a "violation" of the ESA under its citizen suit provision, 16 U.S.C. § 1540(g), rather than whether there has been "arbitrary and capricious final agency action" under the Administrative Procedures Act ("APA"), 5 U.S.C. § 706.[4] Thus, the Court must decide whether Plaintiffs are likely to succeed on the merits of a claim of a violation of the ESA's requirement of the preparation of a biological assessment before the issuance of a biological opinion. Defendants counter Plaintiffs' argument by asserting, among other things,[5] that the consultation 159 package prepared by Defendants and submitted to the FWS was an acceptable substitute for a biological assessment. In support of this argument, Defendants point out that the purpose of a biological assessment "is to evaluate the potential effects of the action on listed or proposed species or designated or proposed critical habitat and determine whether any such species and habitat are likely to be adversely affected by the action." Further, under the relevant regulations, the contents of a biological assessment are chosen at the discretion of the agency seeking the biological opinion. See 50 C.F.R. § 402.12 (2001). The biological assessment, according to Defendants, need only be adequate to "serve as an analytical instrument" that can be used for analyzing the effects of the agency's action. Plaintiffs essentially agree with this characterization of the purpose of a biological assessment, but they argue that the consultation package that Defendants substituted for a biological assessment was not adequate to fulfill the purpose of a biological assessment. In support of the sufficiency of their consultation package as a biological assessment, Defendants assert that the package (1) "evaluated the potential effects of the training activities on listed species and critical habitat and determined whether any such species and habitat were likely to be adversely affected by the action;" (2) "contained the results of the on-site inspections and monitoring of the site;" and (3) "considered the views of the [FWS'] Boqueron Field Office biologists during informal consultation with the [FWS]." According to Defendants, these aspects of the consultation package were "consistent with the framework in the regulations describing the recommended contents of a biological assessment. See 50 C.F.R. § 402.12(f)." Plaintiffs, on the other hand, argue that Defendants' consultation package was not an adequate substitute for a biological assessment. In support of their contention. Plaintiffs assert that the consultation package does not contain "the results of on-site inspections, the views of recognized experts, a review of the literature, an analysis of the effects of the action on listed species or an analysis of alternate actions." This assertion is inadequate to impugn the sufficiency of Defendants' consultation package for two reasons. First, the contents of a biological assessment are discretionary with the agency that prepares it; the regulation governing the contents of a biological assessment lists items that it "may" contain. See 50 C.F.R. § 402.12(f) (2001).[6] Second, even if the items that Plaintiffs list were required, Defendants' consultation package goes a considerable way toward satisfying those requirements. The consultation package, Dkt. No. 12, Exhibit 22, provides a list of endangered and threatened species in the training area, descriptions of the species' habitats and nesting areas, reasons for the species' decline, actions taken to protect the species, results of aerial surveys, and a list of restrictions on military exercises. The Court finds at this preliminary stage that Plaintiffs are not likely to succeed 160 on the merits of a claim of a violation of the ESA's requirement of the preparation of a biological assessment. In other words, Defendants' consultation package is likely to be found to satisfy the requirement of a biological assessment. Plaintiffs' second claim of violation of the ESA's consultation requirements is that the biological opinion issued by the FWS suffers from substantive defects that make its issuance arbitrary and capricious under the APA.[7] The Court shall address these alleged defects in turn. First, Plaintiffs assert that the FWS' biological opinion "fails to consider several cumulative effects on the listed species," including the effects of sonar and "sonobuoys" on listed species. In response, Defendants argue that the FWS "did analyze the overall impacts to the species and the habitat." Defendants counter that the concept of "cumulative effects" refers to the effects of State or private activities in the area and that the FWS did not analyze these effects because it anticipated no such activities. Second, Plaintiffs contend that the FWS' biological opinion failed to the effects on listed species of inert munitions "skipping" off of targets and into the water. Defendants respond that their consultation package adequately addressed skipping and that the FWS determined "that rounds skipping into the water were not likely to adversely affect any listed species." Third, Plaintiffs claim that the biological opinion "fails to mention nighttime firing as a factor that might adversely affected listed species. The biological opinion simply states that the `use of illumination rounds will be minimized to the extent practicable.'" Defendants reply that although the biological opinion does not discuss nighttime firing at length, the consultation package on the basis of which the biological opinion was issued goes into considerable detail regarding the measures that Defendants will take to minimize the impact of nighttime firing on species in the area. Fourth, Plaintiffs contend without support that the FWS failed to use the best available commercial and scientific data in rendering its biological opinion. Defendants counter by stating that the FWS' determinations "are based upon the best available data and consideration of relevant factors." Fifth, Plaintiffs assert that the FWS' biological opinion ignores "the potential impact that mitigation measures such as beach grading and crater filling may have on sea turtle hatchlings." Defendants respond that the biological opinion does consider these issues. The biological opinion states, [i]n the unlikely event that a round/bomb does hit the beach, craters and materials that may affect the ability of nesting or hatching turtles to traverse the beach will be filled and removed to ensure that neither female sea turtles or [sic] their offspring will be trapped. Additionally, any vehicle tracks/ruts running parallel to the amphibious beaches will be removed (i.e. graded) so there will be no impact to turtle hatchlings. Dkt. No. 12, Exhibit 24. Thus, far from ignoring the effect of mitigation measures on sea turtle hatchlings, the FWS' biological opinion discusses mitigation measures as a means of protecting turtle hatchlings. Sixth, Plaintiffs claim that the biological opinion contains insufficient discussion of *161 the plight of the brown pelican. Defendants retort with examples of attempts they have made to accommodate the brown pelican and point out that the biological opinion requires a 1,500-foot minimum altitude for flights, as opposed to the previous 500-foot restriction, for the protection of the brown pelican.[8] Seventh, Plaintiffs assert that the FWS' biological opinion ignores recent literature on "marine mammal and sea turtle survey methodology." Proper consideration of this issue, Plaintiffs aver, would have made clear to the FWS that sea turtle and marine mammal survey flights could be more effectively conducted at times other than those proposed in the biological opinion. Finally, Plaintiffs state that the FWS' biological opinion fails to consider the effect of "acoustic and vibration disturbances" on sea turtles and contains "many substantive and statistical inaccuracies." Plaintiffs offer insufficient evidence in support of these last arguments. It is far from clear, at this preliminary stage, that the FWS' biological opinion suffers from the numerous defects which Plaintiffs attribute to it, much less that these defects satisfy the exacting requirement of rendering the opinion "arbitrary and capricious." Both parties make strong arguments regarding these alleged defects that are in stark opposition. The Court is loathe to substitute its judgment for that of the FWS, especially when under the APA the actions of the FWS need only avoid being found "arbitrary and capricious."[9]See United States v. Hernandez, 979 F.Supp. 70, 76 (D.P.R.1997) (pointing out that "[i]f the agency considered the relevant factors and if the agency did not make a clear error of judgment, then the decision was not arbitrary or capricious"), aff'd, 187 F.3d 623, 1998 WL 1085772 (1st Cir.1998). Thus, the Court finds that Plaintiffs are not likely to succeed on the merits in showing the FWS' biological opinion to be arbitrary and capricious under the APA. 2. Potential for Irreparable Harm Plaintiffs argue that without a preliminary injunction they will suffer two types of irreparable harm. First, they assert that a procedural violation of the ESA's consultation requirements automatically constitutes irreparable harm. Second, they cite the potential for harm to listed species in the event that Defendants' training exercises continue. Plaintiffs state, "[t]he death of even a single member of an endangered species represents irreparable harm since it interferes with breeding opportunities and eliminates genetic material in a diminishing gene pool." Defendants dispute
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380, 2803, 326, 954, 11852, 310, 253, 1511, 273, 19737, 908, 275, 697, 6833, 15, 1310, 19737, 556, 2169, 20791, 13, 253, 11859, 588, 671, 452, 2169, 20791, 15, 380, 8609, 20791, 273, 3626, 29111, 310, 875, 337, 15, 18121, 285, 854, 15, 23, 411, 16, 78, 44, 1254, 35 ]	, for Appellees. Unpublished opinions are not binding precedent in this circuit. See Local Rule 36(c). 3 PER CURIAM: Appellants appeal from the district court’s order denying relief on their 42 U.S.C. § 1983 (1994) complaint. We have reviewed the record and the district court’s opinion and find no reversible error. Accordingly, we affirm on the reasoning of the district court. Minns v. Spore, No. CA-96-512 (E.D. Va. Jan. 23, 1998). We dispense with oral argument because the facts and legal contentions are adequately presented in the materials before the court and argument would not aid the decisional process. AFFIRMED 4 Carol Crawford Carol Ann Crawford (February 22, 1934 – August 10, 1982), also known as Carol Stolkin and Carol Ross, was an American backgammon and bridge player from Buffalo, New York who spent many years in Detroit, Michigan. In 1973, she became the second woman to win the world backgammon championships. She was the second wife of John R. Crawford. Like her husband, she had talent in both backgammon and bridge. Bridge accomplishments Wins Runners-up North American Bridge Championships (3) Chicago Mixed Board-a-Match (2) 1974, 1975 Smith Life Master Women's Pairs (1) 1976 References External links Category:American backgammon players Category:American contract bridge players Category:1982 deaths Category:1934 births Category:Sportspeople from New York City Category:People from Wilmette, Illinois1. Introduction =============== Although concrete is the most commonly used construction material anywhere in the world, it is not considered sustainable because of its destructive nature in the consumption of natural resources and the environmental impact after its use. Approximately 65% of the volume of concrete is aggregate; therefore discovering suitable substitutes for natural aggregates is a priority. By this way, for the construction industry, reusing concrete waste may be an attractive option for the good practice of producing high quality eco-concrete \[[@B1-materials-08-04457]\]. The objective is to integrate environmental aspects into the product design in order to improve its environmental performance throughout its entire life cycle, and in particular its duration and residual treatment \[[@B2-materials-08-04457]\]. Concrete's thermal behavior is relevant to any of its applications, especially in structural concrete where it is ideal to have low thermal conductivity, dimensional stability, high specific heat and little or no decrease in strength with increasing temperature. Research is based on three pillars: use of concrete RAs; analysis of thermal conductivity, as the main parameter to measure energy efficiency; and the use of IRT as a qualitative, non-destructive technique for the study of thermal behavior. The importance of the study lies in the scarce research on thermal properties of this type of concrete, self-compacting with RAs, and validation of thermography as a first approach to the study of thermal conductivity, quantifying the results through a heat flow meter. The current state of the research and publications in the three key areas of research is reviewed below. 1.1. Background of Recycled Aggregate ------------------------------------- With the clear objective of prevention, the Directive 2008/98/EC establishes the legal framework for the treatment of one of the main current environmental problems such as the generation and management of waste from different industries, promoting reuse, and recycling. This Directive has been transposed to the different member states of the European Union, which in Spain was materialized in the current 2014--2020 State Program for Waste Reduction with the aim of reducing 10% of the waste generated in 2010 by 2020. The main product of construction and demolition wastes recovery is the RA, granular material resulting from the treatment of inorganic materials previously used in the construction. Any facility that gives exclusive service to the construction work is considered an integral part of it, including precast concrete plants, among others. The need to reduce the final amount of waste produced in plants of precast concrete, with the intention of using it as RA in new parts manufacturing, thereby reducing the consumption of natural aggregates, is the target for energy efficiency this article is based on. Construction and demolition wastes have been subject of study of many researchers in recent years. Behera et al. \[[@B3-materials-08-04457]\] have conducted a thorough review of the main results, ranging from the process of obtaining the RA; the analysis of the physical and chemical properties of the different types of RAs; analyzing the properties of recycled concrete both fresh and hardened state; and various techniques to improve the properties of RA, as well as the main issues on its use. Out of the three RA types according to their origin (concrete, ceramic or mixed), recycled concrete aggregates object of this study may have two origins: traces of manufacturing (production disposed elements and tested specimens), or demolition of concrete structures. While in the first case the aggregates are relatively clean, with only cement paste attached; in the second case, the aggregate is often contaminated with salts, bricks and tiles, sand, dust, wood, plastic, cardboard, paper, and metals \[[@B4-materials-08-04457]\]. There are few countries that have regulations or recommendations of use for this type of aggregate for structural concrete, finding different trends in the required quality of RA, of the maximum allowed content in concrete, or limitation on its applications. Rilem \[[@B5-materials-08-04457]\], one of the first to be developed, and adopted in other countries such as Belgium or Hong Kong, pioneers in this field, allows the use of RAs with maximum absorption of 10% in concrete with category resistant to 50 N/mm^2^. The Japanese standard \[[@B6-materials-08-04457]\] is more stringent and fixes maximum absorption at 7% for concretes of category resistant up to 24 N/mm^2^, although the most demanding of all is the Spanish regulation EHE-08 \[[@B7-materials-08-04457]\], based on concrete made with coarse recycled aggregate from the crushing of concrete waste. The required characteristics for RA's concrete according to the EHE-08 that most affect this research are: Aggregates from concrete.Coarse aggregate with absorption \<7%.Banned in precast concrete.Minimum aggregate size 4 mm.Replacement of natural aggregate by RA, maximum recommended 20%.Strength limit of 40 N/mm^2^. This project focuses on the aggregate from crushing concrete pieces, which does not comply with quality control in a precast concrete plant in Galicia (Spain). It is reported that the recycled aggregates are relatively weaker than the natural ones, and therefore, compositional differences can be significant depending on the proportion of mortar present in the residue, which is the origin of the worst features of RAs, such as low density, low conductivity, and increased water absorption, Los Angeles coefficient of abrasion, and sulfate content. These characteristics also affect adversely the quality of the recycled concrete related elasticity, shrinkage and creep, as well as durability. The expected properties of recycled concrete with RAs from concrete waste are \[[@B8-materials-08-04457],[@B9-materials-08-04457],[@B10-materials-08-04457],[@B11-materials-08-04457],[@B12-materials-08-04457]\]: Water demand in the fresh recycled concrete is higher than that of fresh concrete made by natural gravel and cement consumption for the same strength is somewhat higher.Recycled concrete density is lower than that of the original concrete; with 100% replacement of coarse aggregate, a density between 10% and 20% lower can be obtained.Substitutions of up to 30% of the conventional aggregate by RA do not significantly alter the compressive strength of the new concrete. When 100% of the coarse aggregate is replaced, the compressive strength may decrease between 10% and 20%.The elasticity module of recycled concrete is always lower (between 15% and 40%) than the reference concrete and reaches even smaller values when recycled fine aggregate is also used.The shrinkage and creep of recycled concrete are maintained when coarse aggregate replacement is less than 20%, whereas with a 100% replacement of coarse aggregate, shrinkage can increase up to 50% and creep between 30% and 60%. If fine recycled aggregate is also used, both values increase even more.For the same dosage, both absorption and porosity of recycled concrete increase. In reference concrete having 5%--6% absorption and 11%--13% porosity, absorption and porosity values between 8%--9% and 16%--20%, respectively, might be achieved. The properties that may in principle be a problem, such as low density and high porosity, in this project are considered an advantage when designing elements aimed at, among others, serving as thermal insulator. It would be worth mentioning, in view of highlighting possible concrete solutions with enhanced eco-friendly features, the possible role of fly ash in concrete with recycled aggregates, in terms of both mechanical performance \[[@B13-materials-08-04457]\] and thermal properties \[[@B14-materials-08-04457]\]. 1.2. Background on Thermal Conductivity of Concrete --------------------------------------------------- Different studies show that the three most influential factors in conductivity are the aggregate type, porosity and moisture. The factor that most affects is the type of aggregate used in its manufacture. If aggregate has higher conductivity, the concrete will also have higher conductivity. The thermal conductivity of natural aggregates is between 1.163 and 8.6 W/mK \[[@B
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436, 673, 1475, 15, 187, 187, 4257, 353, 1267, 20, 44, 4892, 7866, 275, 4437, 15, 31513, 588, 320, 391, 1648, 272, 12936, 10354, 1240, 285, 253, 378, 1502, 15, 1583, 1472, 2509, 14645, 43222, 254, 313, 783, 806, 581, 28, 353, 7, 85, 35, 858, 253, 2626, 581, 896, 275 ]	-based Tailwind was to receive over the term of the deal: $6.1 million in 2001; $7.61 million in 2002; $8.23 million in 2003; and $8.66 million in 2004, plus a total of $400,000 for a junior program. About $700,000 more was added to the deal through contract modifications, which included adding $75,000 for "promotional activities." The 2003 audit conducted by the USPS Inspector General faulted officials for "ineffectively" managing extras, such as event tickets and invitations. "Over the years, many different sponsors have seen -- and continue to see -- the benefits of associating with Lance and his cycling teams," Armstrong spokesman Mark Fabiani said in a statement to The Associated Press. Jim Andrews, a sponsorship expert with the Chicago-based consulting firm IEG, says that this is the first time USPS has publicly acknowledged the specifics of its sponsorship deal, which he calls "very significant, and not standard, but also not unheard of for a top-flight team." The escalating figures show the tangible effect of Armstrong's star power and the leverage it gave Tailwind. The agency's initial contract with the team in 1996 was for $1 million. Armstrong signed with the team before the 1998 season, and won the first of his record seven Tour de France titles in 1999. By 2000, the contract, renewed yearly, had grown to $3.3 million. In 2004, it was more than eight times the original amount. The documents also show the vast discrepancy in bonus payments. An invoice from August 2001 shows Armstrong earned $1.47 million for stage wins, days wearing the leader's yellow jersey and the overall win at that year's Tour. Teammate Tyler Hamilton, whose contract stipulated that he would be the second-highest paid rider after Armstrong, earned just $150,000 in bonuses for the same race. Hamilton, who retired in 2009 after admitting to a second doping offense, testified under subpoena before a federal grand jury that is meeting behind closed doors in Los Angeles. The specific dollar figures revealed in the documents are relevant to more than just that criminal investigation, which began with an inquiry into another American cycling team but ramped up when former Postal rider Floyd Landis confessed to his own use of performance-enhancing drugs and described organized doping on the team. Sources have confirmed to ESPN that Landis, Armstrong's teammate from 2002 to 2004, filed a federal whistleblower lawsuit last spring at about the same time that he made those allegations. The Department of Justice is weighing whether to intervene on Landis' behalf, a move that would greatly increase his odds of success. Plaintiffs are eligible for up to a third of the treble damages that prosecutors can assess if they prove government funds were fraudulently used. Armstrong strongly denies that he ever doped, and ex-aides such as the team's former medical director, Luis Garcia del Moral, have backed him, saying they never saw anything untoward. USPS officials also maintained they had no knowledge of doping on the team. Yet the newly released Postal Service documents show that, as early as 2000, officials were becoming queasy about news stories tying the team to drugs. The four-year renewal struck that year included a "morals turpitude and drug clause," specifically citing "failure to pass drug or medical tests" and "inappropriate drug conduct prejudicial to the team" as causes to suspend or fire riders. Excerpt from "morals" clause. (Click to view entire document) The renewal also included a negative publicity clause that became an issue when a French television crew found suspicious medical waste in trash disposed of by team staff members. The French government subsequently launched an investigation into the team but closed the case two years later. In February 2001, Lynda Zelnick, a USPS contracting officer, wrote to Allen Furst, then the managing director of Tailwind, to warn him about the "the need for prudence and discretion in talking with the media." She also noted "the Postal Service's concern about the deleterious impact upon the anticipated value of our sponsorship" that the news was having, and said that the agency was hiring a PR firm to run interference in the future. The $50,000 cost, she added, was being deducted from the overall sponsorship fee. Andrews says he believes that there are several people with intimate knowledge of the deal who may be asked to come forward by federal investigators. "There's another shoe out there," he said. "I'm just not sure if it will drop. I'm not sure anyone else is going to break their silence." The reason originally cited by USPS for denying the public records request was that "publicizing the price needed to obtain sponsorship rights [would] harm [our] ability to negotiate cost-effective sponsorships" in the future. On the appeal, it was pointed out that the agency no longer maintains sports sponsorships, and any financial information is at least six years old. Shaun Assael is a senior writer for ESPN The Magazine. ESPN.com's Bonnie D. Ford contributed to this report."The officials at The Louvre have until the end of 1389 [the Iranian year ending March 2011] to precisely tell us when and what they are going to set up here," he added. Sensitivities over the French role in the excavation and export of Persian cultural artifacts are nothing new. Throughout the 19th and 20th centuries, France was granted a series of exclusive excavation concessions over important historical sites such as Susa, the capital of the Persian Empire under Cyrus the Great. According to those contracts, as many as half the artifacts found went to the French and many ended up in European private collections or museums. The dispute with the Louvre follows a similar controversy with the British Museum over the exhibition of the Cyrus Cylinder, an ancient clay cylinder with cuneiform script praising the lineage and deeds of Cyrus the Great. The British Museum delayed lending the cylinder to the National Museum of Iran after the disputed 2009 presidential elections and the upheaval that followed, citing security concerns, but Iranian authorities accused the British of playing politics. The controversy was eventually resolved and the cylinder went on display in Iran from September 2010 to January 2011. Photos, from top: The Louvre in Paris is accused by Iranian authorities of failing to live up to an agreement to exhibit artifacts in Iran; the Cyrus Cylinder was at the center of an earlier dispute between Iran and the British Museum. Credits: David Monniaux via Wikimedia Commons; Mike Peel via Wikimedia Commons.I finished the new season. I feel like they were really clicking at the end there, like the growing pains were starting to resolve -- they weren't trying to cram quite so many riffs in, and I could tell Baron and Jonah's voices apart. I'm interested in seeing where they go from here. Meanwhile, Rifftrax has its annual Kickstarter going; this year's live shows will be Space Mutiny and Krull. Kick in at $1 and you get at least two shorts; they'll add another one every 200 backers, up to 10. The episodes are still listed in a completely baffling and inexplicable order. It's not chronological, it's not based on popularity (Manos is in between Girl in Gold Boots and Catalina Caper), it doesn't alternate Joel-Mike-Joel-Mike, and it doesn't follow the order of the DVD releases, so my current working theory is that the episodes are sorted based on the "nobody gave a fuck" algorithm. Regardless, there's some good shit in there. And given that there are nearly 200 episodes in the original series, there are still a lot of them I haven't seen. And of course thanks to the constant churn of movie rights, the list of legally-available episodes is constantly in flux, so watch 'em while you can. (On the subject of not-legally-available episodes, has anyone ever managed to find a rip of the Godzilla vs. Megalon DVD? I've looked but I've only ever found crummy VHS rips. ...shit, I bet I've still got a VHS copy around here somewhere; I should see if mine's in any better shape than the digital copies I've seen up to this point. Same with Fire Maidens from Outer Space and anything else I've got that's not commercially available. I should really go through these tapes before they deteriorate completely.) 372 Pages We'll Never Get Back is basically a Rifftrax Book Club podcast, wherein Conor Lastowka and Mike Nelson read and discuss a book. Season 1 is Ready Player One. I've listened to the intro episode and Episode 1, and I think I'll stick with it even though I haven't read the book and have no intention of doing so. I think I'd probably get more out of it if I'd actually read it, but their summaries and excerpts are enough to follow along. I have also learned that my dog does not give a fuck when people on the car stereo say her name. The most important detail: they're tweaking the format somehow to be a better fit for Netflix and binge-watching; Joel hasn't shared the details except that it's only going to be 6 episodes this time around. New MST3K tour starts in October. Joel will be riffing alongside Jonah and the Bots. They're doing Deathstalker (the first one; M&tB did the third one back in
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1469, 1475, 13, 46551, 598, 387, 253, 5680, 9676, 16618, 13, 369, 22602, 19581, 281, 13, 16831, 13, 3520, 7242, 13, 690, 273, 731, 497, 3981, 15, 1244, 326, 368, 497, 43243, 7217, 15, 3954, 13, 309, 871, 326, 434, 417, 634, 5807, 47487, 13, 390, 752, 368, 1472, 3981, 13, 285, 352, 434 ]	ane Curl was originally committed to prison following a February 24, 1976, conviction for assault with a deadly weapon. (Pen. Code, § 245.) Under the Indeterminate Sentence Law (ISL), applicable at that time, the Adult Authority fixed his term at 20 years. On April 22, 1977, respondent committed and was subsequently convicted of the second degree murder of a fellow inmate while incarcerated at the California Medical Facility, Vacaville. (Pen. Code, § 187.) His ISL term was then set at five years to life, and this sentence was ordered to be served concurrently with the prior assault. After the passage of the determinate sentence law (DSL) (Pen. Code, § 1170 et seq.), respondent's term was recalculated under the DSL to be a concurrent term of six years pursuant to section 1170.2. Six months later, while serving the concurrent sentences at the state prison in Soledad, respondent stabbed two inmates. He pleaded guilty to assault with a deadly weapon (Pen. Code, § 4501) and was sentenced to the upper base term of four years, which was ordered to run consecutively to the terms he was presently serving. Relying on People v. McCart, supra, 32 Cal.3d 338, respondent petitioned the superior court for a writ of habeas corpus. He claimed that Penal Code section 1170.1, subdivision (c) requires that all subsequent terms for in-prison offenses which are ordered to be served consecutively be calculated at one-third of the middle base term as set forth in subdivision (a) of that section. Concluding that the situation in McCart was similar to the instant matter, the trial court granted the writ petition. In light of the difference discussed below, we read McCart to reject the calculation respondent espouses. 239 In People v. McCart, supra, 32 Cal.3d 338, the defendant was convicted of an offense while in prison and was sentenced to a consecutive six-year term. Two months later defendant was convicted of a second in-prison offense, possession of a deadly weapon by a prisoner (Pen. Code, § 4502), which the statute required to be served consecutively. The trial court imposed the full upper base term of four years to be served consecutively to the prior terms. The defendant, McCart, argued that former Penal Code section 1170.1, subdivision (b), renumbered as subdivision (c), required that the length of consecutive terms for multiple in-prison offenses be calculated according to the principal term/subordinate term formula contained in subdivision (a). (People v. McCart, supra, 32 Cal.3d at p. 341.) The Supreme Court agreed, rejecting the People's main argument that the statute reflected a legislative intent to provide full consecutive terms for in-prison offenses where the sentences are imposed in separate proceedings. (Ibid.) The People relied on the language of subdivision (c) which provided "`the term of imprisonment for all such convictions [which such person is required to serve consecutively] shall commence from the time such person would otherwise have been released from prison.'" (Id., at p. 342.) However, the court noted that this argument overlooked the last sentence of the section which read: "`The provisions of this subdivision shall be applicable in cases of convictions of more than one offense in different proceedings, and convictions of more than one offense in the same or different proceedings.'" (Id., at p. 343.) The court concluded that when these provisions were read together it called for "computation of a single term of imprisonment for all convictions of felonies committed in prison and sentenced consecutively, whether multiple convictions occur in the same court proceeding or in different proceedings." (Ibid., italics added.) All contemporaneous, or nearly contemporaneous, consecutive in-prison offenses are to be calculated in the same manner as for nonprison offenses. The instant matter differs from the facts in McCart in one important respect; here, respondent was sentenced to only one consecutive term for his second in-prison offense, not two as in McCart. Penal Code section 1170.1, subdivision (c) reads as follows: "In the case of any person convicted of one or more felonies committed while such person is confined in a state prison, or is subject to reimprisonment for escape from such custody and the law either requires the terms to be served consecutively or the court imposes consecutive terms, the term of imprisonment 240 for all such convictions which such person is required to serve consecutively shall commence from the time such person would otherwise have been released from prison. If the new offenses are consecutive with each other, the principal and subordinate terms shall be calculated as provided in subdivision (a), except that the total of subordinate terms may exceed five years. The provisions of this subdivision shall be applicable in cases of convictions of more than one offense in different proceedings, and convictions of more than one offense in the same or different proceedings." (Italics added.) Giving effect to all the language in the statute (Gay Law Students Assn. v. Pacific Tel. & Tel. Co. (1979) 24 Cal.3d 458, 478 [156 Cal. Rptr. 14, 595 P.2d 592]), it seems clear that the Legislature intended that in-prison offenses, sentenced consecutively, should begin to run from the expiration of the prior term. As applied to the instant matter, the prior term reflects respondent's concurrent sentences for assault with a deadly weapon and second degree murder. It is the Legislature's intention to standardize only those in-prison offenses which are sentenced consecutively. Since respondent received a concurrent sentence for his first in-prison crime of murder, he was not prejudiced and does not fall within the harmonizing purpose of the statute. This reading is consistent with the interpretation of the statute given by the McCart court: "Read together these provisions call for computation of a single term of imprisonment for all convictions of felonies committed in prison and sentenced consecutively, whether multiple convictions occur in the same court proceeding or in different proceedings. That this term is to commence when the person would otherwise have been released emphasizes that the new term is to be fully consecutive to the term already being served: i.e., that it must commence at the end of the longest of the prisoner's previously imposed terms. [Fn. omitted.]" (People v. McCart, supra, 32 Cal.3d at p. 343, italics added.) Applying the foregoing rationale to the instant matter, it seems clear that the first consecutively sentenced in-prison offense; i.e., assault, is to be a full term which commences at the end of respondent's concurrent term. Accordingly, it was error to reduce the sentence for the in-prison assault to one-third of the middle base term; i.e., one year, instead of the four-year principal term originally imposed. (2) The People next argue that section 1170.1, subdivision (c) does not apply here since the in-prison offenses were committed in different counties. We disagree. Although the murder was committed while Curl was incarcerated at the California Medical Facility in Vacaville, Solano County, and *241 the more recent assault with a deadly weapon was committed while Curl was confined to the state prison in Soledad, Monterey County, it is irrelevant, as the McCart court pointed out, whether the convictions occurred in the same court proceeding or in different proceedings. (People v. McCart, supra, 32 Cal.3d at p. 343.) Likewise, the overriding purpose of uniformity and proportionality in prison terms would not be achieved if such terms were determined by the respondent's fortuity to have committed the crimes in the same county. (Id., at p. 346.) The order granting the petition for a writ of habeas corpus is reversed. The original sentence imposing a full consecutive term of four years remains in effect. King, J., and Haning, J., concurred. A petition for a rehearing was denied December 23, 1983, and the opinion was modified to read as printed above. ShareThis “There are two novels that can change a bookish fourteen-year old’s life: The Lord of the Rings and Atlas Shrugged. One is a childish fantasy that often engenders a lifelong obsession with its unbelievable heroes, leading to an emotionally stunted, socially crippled adulthood, unable to deal with the real world. The other, of course, involves orcs.” ― Paul Krugman Support A Liberal's Hit List Twitter Feed About Hi, I'm Bret. I'm a very Progressive Liberal. I believe in the truth behind science and mathematics. I believe supposed "creationists" are just too ignorant to understand actual science, and fall back to their magic storybook because real science is too hard for their itsy-bitsy lizard brains. I believe in equality for all people; straight, gay, bi, trans, white, black, brown it does not matter. We are all humans on this Earth for a limited time. Celebrate diversity and enjoy with other's bring to your life. End of story. ;-) Neil Cavuto, for instance, hosted Gilchrist on his Fox News show Oct. 16, and mostly blew sunshine up Gilchrist's butt, talking about how he was a war hero, and didn't those mean students know he had fought for their free-speech rights, blah blah blah. Then he added: Cavuto: What the kids were saying in those pre-law classes was that you were going around, rounding up at the border illegal immigrants, was tantamount to, uh, physical abuse, some of them were saying. And that you were advocating violence. Now, I know that's not your schtick, or what you're saying, and it's
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9222, 15, 329, 1943, 33517, 6680, 15, 1500, 1912, 626, 1918, 779, 326, 15, 1500, 1833, 2619, 441, 745, 581, 407, 581, 15, 831, 3548, 626 ]	likely coming up the main road—though he was prepared if they came over either ridge, too. The half-deads would try to swarm over the cops in the Hollow, and then Justinia Malvern would make her dramatic entrance, draining any survivors of blood before she went for the main prize. The paddy wagon. It stood in the middle of the clearing just waiting to be torn open so Malvern could get at the vampire hunter within. Of course Fetlock didn't plan to actually let that happen. His intention was to have his windbreakers engage the half-deads with a withering cross fire, then let Malvern come swooping in right into the sights of half a dozen snipers. Even then he had backup plans. The best sharpshooters he had might not be enough to take down a vampire, and he knew it—vampires were devilishly fast, and snipers were most effective against stationary targets. He claimed to have some surprises hidden in his mobile command center, things he wouldn't tell Clara and Glauer about. He also had his helicopter, though what it could do remained to be seen. "We had helicopters at Gettysburg," Glauer had told him, arguing patiently while Fetlock just gloated. "Didn't help much." "You used them there as support vehicles, mostly for intelligence gathering. Trust that I paid attention when I read your reports, Special Deputy." Glauer had shrugged and asked no more questions. So that was the trap, which Clara had to admit sounded formidable. Meanwhile Darnell was up on the ridges making sure it didn't prove too impregnable, that it didn't scare Malvern off before she even got into Fetlock's crosshairs. Fetlock and Urie Polder had figured out a way to make it look like the cops had foolishly ruined their own first line of defense. Rather than just take down the cordon of teleplasm and the perimeter of shrieking bird skulls, Darnell would tear down a few of the teleplasmic sheets as if he had been forced to do so to sneak in when he first started spying on the Hollow (he had actually been able to bypass them easily), then kick dirt over a couple of the skulls as if he'd carelessly disturbed them. They were fragile charms and easily disabled, and it was possible to make it look like he'd done so by accident. As a result of these efforts there would be a clear path for the half-deads to take through the defenses and right into Fetlock's traps, but it wouldn't look like they'd been given an engraved invitation. By the time the sun set behind the western ridge, everything was in place. As twilight fell across the tree-lined slopes that hemmed them in on either side, Clara felt the muscles of her back stiffen and tense. She watched the last rays of red sunlight cut through the puffy clouds as if she would never see them again. "Won't happen right away," Glauer told her. "I know," she replied. It was very unlikely that Malvern would strike exactly at sunset. She had to sleep all day in her coffin. They had no idea where that coffin might be, but it probably wouldn't be within ten miles of the Hollow. So she would have to travel to the trap, which might take ten minutes or it might take hours. And she was far too clever to stick to any expected timetable. She would strike when they least expected it. Which meant they had to expect it to come at any moment. Glauer and Clara kept wandering back and forth across the clearing, even as it grew so dark they could barely make out each other's faces in the twilight. Even when they started tripping on tree roots and rocks. They had not been given orders to stop. Every inch of Clara's skin prickled with fear. Every pore of her body exuded greasy fear sweat, though the temperature dropped rapidly as the darkness grew complete. Every instinct she had told her to run away. "Might not happen tonight," Glauer said, his voice strangely loud in the dimness. "You know it will," she said. Still. Fifteen minutes passed in full darkness, and nothing happened. An hour passed, and nothing happened. Two hours. "Oh my God, come on already!" Clara screamed, trying to break the tension. Nearby one of the windbreaker cops grabbed his gun and trained it on her, his eyes wide, his back heaving as he sucked in breath. Apparently she wasn't the only one going crazy with the waiting. She tried to control herself. She nearly jumped out of her skin when a radio crackled somewhere behind her. She spun around and saw Fetlock leaning out of the back of the mobile command center. Yellow light painted half his face. He had a walkie-talkie in one hand and he brought it up close to his mouth. "Unit Nine? Say again," he ordered. "Unit Nine reporting contact," the walkie-talkie replied. The man on the other end of the connection sounded tense and harried. "We have multiple subjects, moving through the tree line, at locations Whiskey Three and again at Yankee One. Repeat, we have—" The man fell silent. Clara couldn't move a muscle. All she could do was stand there and watch Fetlock's face. Nothing in it changed. "Unit Nine, say again," Fetlock ordered. But Unit Nine didn't repeat his information. Instead he started screaming, a terrible, tinny little sound coming from the walkie-talkie. The sound of a man being torn to pieces while he was still alive. There was no question. The attack was starting. ## 42. The Fed reached down and lowered the volume on his radio, but Clara knew the man up on the ridge was still screaming. She could hear it directly now, floating on the air. "Everyone stay frosty. Maintain your posts," Fetlock called to the cops in the Hollow. "This is what we planned for. What we've been training for the last month." There were a few cries of assent, of determination. Most of the cops just kept their heads down. They'd heard the stories. They knew what happened when the police tried to fight vampires. So did Clara. "Glauer," she said. "Glauer, this is going to get bad." "I know," he told her. "Now shut up." She started to protest, but she knew he was right. Worrying about what came next wouldn't change it. Talking about it only made the apprehension worse. "All sniper units, report in," Fetlock said into his walkie-talkie. One by one, eight men called in to report no contact. Up on the ridge the screaming stopped. Not as if the man up there had been finished off. Just as if he'd run out of breath and couldn't make any more noise. "He should bring up the helicopter—get a better visual on the situation—light some flares," Clara muttered. She couldn't help herself. "He should give us guns." "I know," Glauer said again. "Ground units, report in," Fetlock said. One by one the SWAT troopers and the windbreakers started calling in. Just confirming they were still alive. "Infrared, give me a report," Fetlock said. "No contact. No movement," the walkie-talkie said. "IR? Why is he using IR? Half-deads don't radiate heat. He should be using night vision instead, so—" "I _know_ ," Glauer insisted. Then he grabbed her arm. He must have seen something. Something Clara missed. Off to one side of them, a windbreaker cop started turning around, bringing his gun up. Something snatched him out of the dark and pulled him back into the woods, so fast he didn't have a chance to report on it. A moment later he started screaming. He was not fifteen yards away from where Clara and Glauer stood. The SWAT troopers opened fire on where he'd been. There was no way they could be sure they weren't shooting their own man, but they must have had orders to shoot anyway. Carbines barked and spat as bullets tore through the dark trees on that side of the Hollow. "Now, lights!" Fetlock called, and a bank of floodlights on top of the mobile command center swiveled in that direction and flared to life. Clara just had time to see a skinless face peering out from between two tree trunks before it flickered away, too fast to follow. More bullets snapped off in the direction of the half-dead, but it was long gone. "Ground units, fire at will," Fetlock called. But there was nothing to shoot. The man in the woods had stopped screaming almost at once. Clara listened hard for any kind of movement in those trees, peered into the shadows for any human-shaped silhouette. But there was nothing. "Guerrilla tactics," Glauer said. "What?" Clara demanded. "She knows that Fetlock wants a frontal assault. A big pitched battle. She won't give him that. She'll pick us off one by one. This isn't
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15, 681, 16, 31510, 16, 35360, 16, 8882, 3, 187, 186, 3, 7280, 15, 681, 16, 31510, 16, 35360, 16, 14005, 3, 187, 186, 3, 7280, 15, 681, 16, 31510, 16 ]	the Credit Information Bureau and offer legal, debt collection, personal bankruptcy and financial liquidity advice. 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Dedicated Online Platform Marshal Lion experts and its dedicated digital platform will make it much easier for investors (so far unable to do so) to invest in the non-bank loans market and profit from it. Everybody benefits from our modern and decentralized approach to finances which allows for the reduction in the number of middlemen, lower cost and less misunderstanding. Automation makes every process faster, cheaper and much, much safer. As part of our dedicated platform, Marshal Lion will make it possible to use its token to invest in the company’s products. Owing to smart contracts and decentralization allowing for unilateral analysis of any project by any potential investor, the safety of the process is guaranteed. 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WEB: https://marshalliongroup.com Facebook: https://www.facebook.com/Marshal-Lion-Group-1764544916981990/ Instagram: https://www.instagram.com/marshalliongroup_com/ LinkedIn: https://www.linkedin.com/in/marshal-lion-group-18a0a018a/ Twitter: https://twitter.com/marshal_lion Medium: https://medium.com/@marshal_lion Reddit: https://www.reddit.com/user/MarshalLionGroup Telegram: https://t.me/marshal_lionNFL Draft Report Tannehill headlines five visitors to One Bills Drive With the deadline to bring prospects for the 2012 NFL Draft looming on Wednesday, the Buffalo Bills brought in what will likely be their final pre-draft visitors to team facilities on Tuesday. According to BuffaloBills.com, Texas A&M quarterback Ryan Tannehill, South Carolina defensive end Melvin Ingram, Mississippi State defensive tackle Fletcher Cox, South Carolina cornerback Stephon Gilmore and Oklahoma cornerback Jamell Fleming all made the visit to One Bills Drive. If this were two months ago, Ingram visiting would probably be the headline. But with both Mario Williams and Mark Anderson signed to the Bills via free agency, combined with how Buddy Nix views the defensive end class at the top of the draft, it doesn't appear as though he'll be the player selected at 10. Gilmore is an intriguing case. Numerous reports have him shooting up draft boards. Peter King of Sports Illustrated thinks he could go as high as seventh to Jacksonville. With the Bills in need of a cornerback, he could be on the short list of candidates the Bills could think about for their selection at tenth overall. Fleming is a second-tier type of cornerback that could be had on the second day of the draft at some point. As for Tannehill, you can read about how to look in to his visit to Buffalo here. All in all that's 26 total visits that were reported. Teams are allowed a grand total of 30, so it's very possible four players snuck in and out of Buffalo without it being reported.Q: How to disable Client-side Validation for an XPage? I know i can disable for the server or application in the xsp.properties via: xsp.client.validation=false And at the control level via: disableClientSideValidation="true" Short of setting disableClientSideValidation for each control, is there any way to disable at the XPage level? A: Please try the following: <?xml version="1.0" encoding="UTF-8"?> <xp:view xmlns:xp="http://www.ibm.com/xsp/core"> <xp:this.properties> <xp:parameter name="xsp.client.validation" value="false" /> </xp:this.properties> </xp:view> Q: startActivityForResult(Intent, int) what is the purpose of the integer argument I am following a tutorial that uses "startActivityForResult" function. I know why this function is used and if we want to use the returned data, we use onActivityResult() function. The thing that I wana know is, why do we pass an Integer to startActivityForResult() function? And where is it used? Thanks for your kind help! A: When the Activity that you're starting finished, that second argument is passed to the method onActivityResult() of the calling Activity. This is to distinguish different results from one another. You may have a case where an Activity needs to call several others for results, and by specifying a unique int for each of them, you can determine the correct thing to do when you get a result. Edit: Here's an example. Suppose you have a screen (Activity A) where you choose a picture from your gallery, and you choose a friend to send it to. You'll start an activity to pick a picture from the gallery on a button click, and maybe you also have a "friend picker" activity which you can also start from Activity A. You want both of those activities to return the data the user selected. onActivityResult() will get called on Activity A when the user finishes with the two activities described above. By specifying the requestCode for startActivityForResult() for the gallery activity, and your "friend picker", you know what to do in onActivityResult(). Also, note that you don't need a complicated scheme for requestCode. You could just pass in the values 1 and 2 for the gallery and friend picker, respectively. {.NET + SQL_Server + Azure + devLeadership + technology} Menu Rocky Lhota at CNUG I had a chance to ask Rocky a couple of questions that had been bugging me about CSLA. 1) He agreed that using the method of multiple result sets in datareader is not really a good idea in some instances, where a dataset would be much more useful. 2) He suggested that you should usually not have an object that is sometimes a child and sometimes a parent. I am not sure I agree with idea. I believe I understand his point that if you are dealing with a Project object that has a collection of Employees assigned to it, you probably don’t need the Employees to be as complex as if you were dealing with an Employee who is assigned to a bunch of Projects, but at the same time you are talking about writing 2 classes with 2 sets of data access scripts, vs 4 classes and 4 sets of data access. But, he said that there are techniques for making a business object be both a parent and a child. This is apparently detailed in Ch 7. 3) He mentioned that people have built UI Frameworks that run on top of CSLA. I will have to look into this. 4) He was showing an example using an ASP.NET MultiView control, looked like a great way to enable multiple views of the same data. 5) I didn’t get a chance to ask him about serialization and deserialization of classes that have small differences. For example if you serialze an object and use the same byte array to deserialize a similar class, will it blow up if small changes are made, like you add a public property? I will have to try this out myself. In all, Rocky was a very good speaker. Very engaging, funny, and on point. Oh and I won the raffle at the end, to get a copy of his book, the one I just paid 60 bucks for :-).package handlers import ( "fmt" "net/http" "net/url" "github.com/docker/distribution" dcontext "github.com/docker/distribution/context" "github.com/docker/distribution/reference" "github.com/docker/
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23069, 11979, 432, 10329, 5235, 246, 8707, 534, 760, 9164, 595, 3486, 5312, 2098, 5286, 6788, 496, 436, 1083, 13, 2299, 13, 984, 253, 3310, 387, 2523, 275, 253 ]	for its breadth," FMC Corp. v. Holliday, 498 U.S. 52, 58, 111 S.Ct. 403, 112 L.Ed.2d 356 (1990), and "deliberately expansive, and designed to establish pension plan regulation as exclusively a federal concern," Pilot Life Ins. Co. v. Dedeaux, 481 U.S. 41, 46, 107 S.Ct. 1549, 95 L.Ed.2d 39 (1987) (internal quotation omitted). More recently, however, the Supreme Court has narrowed the preemptive scope of ERISA, moving away from the broadest meaning of the provision. The Court has stated that the phrase "insofar as they ... relate" contains words of limitation that were purposefully written into the statute. N.Y. State Conference of Blue Cross & Blue Shield Plans v. Travelers Ins. Co., 514 U.S. 645, 655, 115 S.Ct. 1671, 131 L.Ed.2d 695 (1995). If the term "relate to" was allowed to reach to its most logical extension, "pre-emption would never run its course." Id.; see also Cal. Div. of Labor Standards Enforcement v. Dillingham Constr., N.A., 519 U.S. 316, 335, 117 S.Ct. 832, 136 L.Ed.2d 791 (1997) (Scalia, J. concurring) (noting that "applying the `relate to' provision according to its terms was a project doomed to failure, since, as many a curbstone philosopher has observed, everything is related to everything else"). The effect of such a broad reading "would be to read Congress's words of limitation as mere sham, and to read the presumption against pre-emption out of the law whenever Congress speaks to the matter with generality." Travelers Ins. Co., 514 U.S. at 655, 115 S.Ct. 1671. 12 Therefore, in interpreting ERISA's preemption clause, a court "must go beyond the unhelpful text and the frustrating difficulty of defining its key term, and look instead to the objectives of the ERISA statute as a guide to the scope of the state law that Congress understood would survive." Id. at 656, 115 S.Ct. 1671. The purpose of ERISA preemption was to avoid conflicting federal and state regulation and to create a nationally uniform administration of employee benefit plans. Thus, ERISA preempts state laws that (1) "mandate employee benefit structures or their administration;" (2) provide "alternate enforcement mechanisms;" or (3) "bind employers or plan administrators to particular choices or preclude uniform administrative practice, thereby functioning as a regulation of an ERISA plan itself." Coyne & Delany Co. v. Selman, 98 F.3d 1457, 1468 (4th Cir.1996) (outlining the three categories of state laws recognized in Travelers that are preempted by ERISA) (internal citations omitted). Congress did not intend, however, for ERISA "to preempt traditional state-based laws of general applicability that do not implicate the relations among the traditional ERISA plan entities, including the principals, the employer, the plan, the plan fiduciaries, and the beneficiaries." LeBlanc v. Cahill, 153 F.3d 134, 147 (4th Cir.1998). 13 Since the Travelers decision, the Supreme Court has reiterated the approach of looking to the objectives of ERISA to guide its preemption decisions. See, e.g., Dillingham Const., 519 U.S. at 325, 117 S.Ct. 832 (finding that California's prevailing wage law, which has only an indirect economic effect on employee benefit plans, is not preempted by ERISA); De Buono, 520 U.S. at 815-16, 117 S.Ct. 1747 (upholding state tax on health care facilities operated by an ERISA fund). We too have followed the Travelers approach in applying ERISA preemption in our recent cases. In Smith v. Provident Bank, 170 F.3d 609, 615-16 (6th Cir.1999), we held that an ERISA plan's state-law claims against a trustee were preempted because Congress established the exclusive means by which fiduciary duties would be enforced. We noted, however, that where "an ERISA plan's relationship with another entity is not governed by ERISA, it is subject to state law." Id. at 617. Similarly, in Marks v. Newcourt Credit Group, Inc., 342 F.3d 444, 453 (6th Cir.2003), we found that a breach-of-contract claim was not preempted where the conduct at issue related to the "employment contract irrespective of the plan" even though resolution of the claim affected the plaintiff's right to plan benefits. Though we have yet to address the issue specifically, other courts of appeals have followed a similar approach and held that ERISA does not preempt state-law claims brought against non-fiduciary service providers in connection with professional services rendered to an ERISA plan. See, e.g., Gerosa v. Savasta & Co., 329 F.3d 317, 330 (2d Cir.2003) (concluding that ERISA does not preempt plan's state-law claim against an actuary which resulted in severe under-funding of ERISA plan), cert. denied, 540 U.S. 967, 124 S.Ct. 435, 157 L.Ed.2d 312 (2003) and cert. denied, 540 U.S. 1074, 124 S.Ct. 929, 157 L.Ed.2d 744 (2003); Ariz. State Carpenters Pension Trust Fund v. Citibank, 125 F.3d 715, 724 (9th Cir.1997) (concluding that a plan could bring a state-law claim for breach of custodial agreement against a bank as non-fiduciary service provider); Coyne & Delany Co., 98 F.3d at 1466, 1472 (holding that state malpractice claims against insurer for negligently failing to obtain replacement insurance plan was not preempted); Airparts Co. v. Custom Benefit Servs., 28 F.3d 1062, 1066 (10th Cir.1994) (concluding that trustee's common-law suit against outside financial consultant is not preempted). 14 Applying these principles to this case, we conclude that the magistrate judge erred in his analysis of PONI's state-law claims against NCB and MVP. The magistrate judge found that because PONI's breach-of-contract claims arise out of obligations relating to the servicing of ERISA plans, the claims against both NCB and MVP are preempted. The mere fact that an employee benefit plan is implicated in the dispute, however, is not dispositive of whether the breach-of-contract claims are preempted. PONI argues that its state-law claims relate solely to the Appellees' record-keeping services and should be viewed separately from the plans themselves. With regard to the claim against NCB, we find that argument to be unpersuasive. 15 NCB serves as trustee to the Savings Plan and also provides record-keeping and commercial-banking services. NCB's record-keeping obligations arise out of the Savings Plan itself, which contains provisions outlining the top-heavy rules and requiring coordination of top-heavy testing among multiple plans.1 In the prior cases in which the courts have found that ERISA does not preempt state-law claims against non-fiduciary service providers, a service agreement or contract separate and distinct from the ERISA qualified plan served as the basis for the claim. See Marks, 342 F.3d at 453 (allowing suit for breach of employment contract); Gerosa, 329 F.3d at 319 (permitting suit on actuarial contract); Ariz. State Carpenters, 125 F.3d at 718 (allowing claim for breach of custodial agreement); Coyne & Delany, 98 F.3d at 1471 (permitting malpractice claim on contract to design benefit plan); Airparts Co., 28 F.3d at 1066 (permitting suit on a consulting contract). In this case, by contrast, all of NCB's obligations arise from the plan itself, and thus the breach-of-contract claim is necessarily a claim that a fiduciary breached the terms of the ERISA plan. 16 PONI argues that even if the contract upon which it is suing NCB is the ERISA plan, preemption does not apply to a state-law breach-of-contract claim for NCB's failure to perform its non-fiduciary duties under the plan. PONI correctly contends that an entity may serve both in a fiduciary and non-fiduciary capacity, because fiduciary status under ERISA turns on function rather than form. Pegram v. Herdrich, 530 U.S. 211, 225-26, 120 S.Ct. 2143, 147 L.Ed.2d 164 (2000). Indeed, where the alleged conduct by the fiduciary is "entirely unrelated to and outside the scope of [the fiduciary's] duties under the plan or in carrying out the terms of the plan," courts have found that ERISA's core objectives are not implicated and state-law claims may proceed. Darcangelo v. Verizon Communications, Inc., 292 F.3d 181, 193 (4th Cir.2002); see also Dishman v. UNUM Life Ins. Co., 269 F.3d 974, 984 (9th Cir.2001) (holding that ERISA does not provide fiduciaries "with blanket immunity from garden variety torts which only peripherally impact daily plan administration"). In this case, however, because the contract at issue in the
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6968, 1792, 5286, 13, 3569, 285, 30270, 23809, 4035, 281, 11089, 15, 3032, 9459, 310, 7943, 407, 5054, 36879, 318, 13, 1408, 1977, 16933, 15, 380, 2644, 2586, 310, 247, 12909, 267, 4840, 15, 3032, 2208, 310, 1077, 1175, 387, 10264, 3237, 835, 1327, 13164, 15, 733, 369, 247, 9459, 273, 19485, 273, 3569, 285, 5054, 7075, 15 ]	from this insight. Contributors: RdR wrote this paper, under supervision of SJSS, CJHvdK, SAEP, and CDAS. All authors reviewed the draft paper and provided critical intellectual content. All authors approved the final version of the manuscript and its submission to BMJ Open Diabetes Research & Care. CDAS is taking responsibility for the contents of the article. Funding: This study was supported by ZonMw (project no 849200001), the European Regional Development Fund via OP-Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant 31O.041), Stichting De Weijerhorst (Maastricht, the Netherlands), the Pearl String Initiative Diabetes (Amsterdam, the Netherlands), CARIM, School for Cardiovascular Diseases (Maastricht, the Netherlands), School CAPHRI, Care and Public Health Research Institute (Maastricht, the Netherlands), NUTRIM, School of Nutrition and Translational Research in Metabolism (Maastricht, the Netherlands), Stichting Annadal (Maastricht, the Netherlands), Health Foundation Limburg (Maastricht, the Netherlands) and by unrestricted grants from Janssen-Cilag B.V. (Tilburg, the Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, the Netherlands) and Sanofi-Aventis Netherlands B.V. (Gouda, the Netherlands). Competing interests: None declared. Patient consent for publication: Not required. Ethics approval: The study has been approved by the institutional medical ethical committee (NL31329.068.10) and the Minister of Health, Welfare and Sports of the Netherlands (Permit 1 31 088--1 05 234 PG). Provenance and peer review: Not commissioned; externally peer reviewed. Data availability statement: Data are available upon reasonable request. Rose Setten Rose Setten (born 22 August 1988, in Shoreham-by-Sea, England) was the 2004 winner of BBC Young Choirgirl of the Year. Setten's achievement was particularly noteworthy because at the time she was head chorister at a small provincial parish with limited resources, All Saints Church in Findon Valley, and was competing against professional choristers from York Minster and Winchester Cathedral, amongst others. She completed her schooling at Davison High School and Brighton Hove & Sussex Sixth Form College. She started singing lessons at the age of 11, and has performed on Songs of Praise and BBC Radio 4's Sunday Half Hour. Setten studied at the Royal Northern College of Music and obtained a first class honours degree in June 2010. She then attended the Royal Academy of Music under Elizabeth Richie as a Mezzo Soprano until June 2013 having been awarded a Distinction in her M.A. as well as the prestigious Dip RAM. In September 2013, Setten commenced studies on the Artist Diploma course at The Benjamin Britten International Opera School at the Royal College of Music. Here, she took the lead role of L'Enfant in L'Enfant et les Sortileges in December 2013. She followed this by playing the part of Tauride in the RCM's March 2014 production of Arianna in Creta, which was part of the London Handel Festival. In November 2014 Setten took the part of Zweite Dame in Die Zauberflote at the RCM . She will be appearing in Cosi Fan Tutte at Garsington Opera in July 2015 covering the role of Dorabella . External links Category:People from Shoreham-by-Sea Category:Living people Category:1988 births Category:21st-century English singers Category:21st-century English women singersQ: "stroke-dasharray:x,y;" mess up svg path? (Chrome) Edit > Fixed: https://bugs.chromium.org/p/chromium/issues/detail?id=364866 Works I generate svg paths via d3js. Either data() + mesh() or datum() + mesh() work. svg.append("g").attr("id","border") .attr("style", "fill: none; stroke:#646464;") .selectAll("path") .data([topojson.mesh(json, L0, function(a, b) { return a !== b; })]) .enter().append("path") .attr("d", path); or : //inland borders lines svg.append("g").attr("id","coast") .attr("style", "fill: none; stroke:#646464;") .append("path") .datum(topojson.mesh(json, json.objects.admin_0, function(a,b){return a===b;})) .attr("d", path); Breaks Adding stroke-dasharray: 8,4 result into: Changing it to stroke-dasharray: 6,3,3,3 result into: Some artifacts appears, and half of the strokes are missing/invisible (borders with Ind/Pakistan, Ind/Nepal, Ind/Myamar, Myamar/Cambodia). If I add a similar stroke-dasharray to the coastline generation, same mess appear with blue lines. Edit: Ok. First, i'am squizzed because the topojson.mesh() always return a single MultiLineString which, in turn, generate a single path. But why is it that the "dasharray:none" works fine !?? Any idea ? I think these dasharray makes a portions of the path not closed. (check up ongoing). Link to live code: https://rugger-demast.codio.io/2_zoom/index.html A: This is a known bug in Chrome: https://code.google.com/p/chromium/issues/detail?id=364866 Edit > Fixed: https://bugs.chromium.org/p/chromium/issues/detail?id=364866 Nigerians: Are You Better Off Today Than You Were Four Years Ago? By Bayo Oluwasanmi During the American presidential debate in 1980 with the incumbent President Jimmy Carter, candidate Ronald Reagan pointedly asked Americans: “Are you better off today than you were four years ago? Ever since, the now-famous quote features prominently every four years in the American political discourse. That one-liner has become a line that people all over the world can personally relate to in many ways.In 2015, former President Goidluck Ebele Jonathan humiliated at the polls was a goner. The departure of the native son of Otueke aroused near-erotic ecstasy of Nigerians who loathed him with such intensity it’s hard to think of a comparison with any democratically elected president in Nigeria. Candidate Muhammadu Buhari is not in any way near an orator. He’s not a fast thinker. He’s slow in decision making and sluggish in action. He prevaricates. But on the promise of killing corruption before corruption kills us, Buhari was overwhelmingly elected president.Riding on populist agenda to fight corruption and sanitize our nation of all economic and social demons of all sorts, he took office May 29, 2015 with Nigerians weeping with happiness. It was a time of a lot of eager, nostalgic, and liberal feelings among Nigerians. The acceptance of and respect for Buhari were tellingly electrifying. Now nearing its four-year term, the Buhari administration was the beginning of the end of a society that bears resemblance to a country with a government. His presidency has become a misery memoir. I hope Nigerians have learned their lesson.History is an amazing guide if Nigerians chose to pay attention to it. But sadly, many Nigerians don’t give a damn. Nigerians, consider the following and conclude whether you were better off today than you were four years ago when Buhari took office.Real change was Buhari’s slogan. His populist agenda of fighting corruption, creating jobs, guarantee of safety and security, extermination of Boko Haram terrorists, and the hope for the realization of common dreams of all Nigerians evaporated like tantalizing mirage.We don’t need a fictional George Orwell to tell us that basic infrastructures are non-existent in Nigeria. Like ancient curse, the same old problems continue to haunt Nigerians. The solutions proferred and preferred by Buhari administration to the old problems are laughable. For water, dig borehole. For electricity, buy generators. For roads, get comfortable on pothole roads. For public transportation, hop on okada (commercial bike). For police rely on neighborhood vigilantes. For public housing, sleep under Eko Bridge. For jobs, sell re-loadable calling cards. Better still, give market women who sell peppers, iru, ogiri, yam, etc., N10,000 and call it TraderMoni. And for health, don’t get sick and if you’re sick, die quickly. Under Buhari administration, political and socioeconomic reforms continue to suffer. His regime is characterized by economic stagnation, run away corruption. The whole country is a dysfunctional mess. His government is very good at manufacturing problems where non existed. It was a regime of reign of political and economic terror.
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13, 359, 651, 513, 1805, 281, 1265, 342, 253, 2934, 326, 7497, 403, 26401, 18366, 14965, 13, 14965, 326, 13791, 15, 187, 187, 2042, 776, 6355, 403, 1175, 13, 359, 588, 320, 973, 2217, 15, 1310, 776, 10924 ]	localNotification.soundName = UILocalNotificationDefaultSoundName; localNotification.applicationIconBadgeNumber = 1; [[UIApplication sharedApplication] scheduleLocalNotification:localNotification]; } A: First of all you should consider the fact that UILocalNotification class that you are using is deprecated starting from iOS 10. Since iOS 10 there is no distinction between local and remote notifications. In UserNotifications framework (iOS 10.0+, Swift \| Objective-C) one does not create instances of UNNotification like in some of the previous implementations of similar frameworks / API's by Apple. Instead, an instance of UNNotificationCenter is responsible for creating notification objects and calls delegate methods when new notifications are received and before the default UI will be displayed. See Apple's documentation for more details on the requirements for conforming UNUserNotificationCenterDelegate protocol. I often end up using AppDelegate as a class conforming to that protocol Now back to the question. To initiate a creation of the notification from within the app first you should create a trigger (in your case you might want to use UNTimeIntervalNotificationTrigger), then create a notification request and finally add the request to the notification center singleton that can be accessed by calling UNUserNotificationCenter.current(). let content = UNMutableNotificationContent() content.title = "Alert Fired" Create a trigger that will determine the moment when UNUserNotificationCenter will invoke the notification let trigger = UNTimeIntervalNotificationTrigger(timeInterval: 0, repeats: false) Create a notification request. You only create those to invoke local notifications, since iOS is responsible for creating request objects for incoming push notifications. let request = UNNotificationRequest(identifier: "FiveSecond", content: content, trigger: trigger) Now we will have to add our request to the current notification center associated with our app. let center = UNUserNotificationCenter.current() center.add(request, withCompletionHandler: nil) In our case the notification will be triggered immediately by the UNUserNotificationCenter. Q: Who exactly knew that Chancellor Palpatine was Darth Sidious? There are only few people who know it. I can include the following people: Count Dooku/Darth Tyranus - I'm sure he told Dooku, because he played such a huge role in Palpatine's plans and the war, so he would always have to know what's going on. Plus by the look on his face when Palpatine told Anakin to kill him, he looked at him like he knew who he was. Mas Amedda - I think he knew, because Palpatine would have told him so they could work together in the Galactic Senate to get whatever results Palpatine wanted, plus in an episode of The Clone Wars, Palpatine says something to him about his plan coming together. Sly Moore - I think she had as much of a major role with Palpatine and the Galactic Senate as Mas Amedda did. During the speech of the Emperor in Revenge of the Sith, she was there. Did Darth Maul and General Grievous know that Palpatine is Darth Sidious? Note: the idea for this question came from http://boards.theforce.net/threads/who-exactly-knew-chancellor-palpatine-was-darth-sidious.50009052/ A: Besides those you mentioned, a few others knew his identity. Ahsoka Tano: The shadow was almost certainly one of the dark side’s creatures. Ahsoka had no idea what sort of thing it might be, but whatever it was couldn’t be that powerful, because it hadn’t been able to track down Hedala. That ruled out Palpatine himself, not that the Emperor could just show up on a planet without causing a great deal of alarm. (Ahsoka) Eneb Ray: While it's never explicitly stated in the canon that Maul knew, it's very likely he made the connection at some point, given that he recognized the Empire as his enemy. He did know in the Legends continuity, though. What then if- beyond contemplation- something should befall his Master? Unlike Darth Sidious, who masqueraded as Republic Senator Palpatine and debated complex issues in the Senate, Maul lacked a secret identity. With his yellow eyes and horned head a black-and-red mask of arcane sigils, it was all he could do to prowl the fringes of The Works in the dead of night without instilling fear in nearly every being whose gaze he caught. (Darth Plagueis) Yoda, Windu and the various other Jedi who learned his identity in Revenge of the Sith, as well as Luke Skywalker. Tarkin had his suspicions: Tarkin may also have determined that Vader was a Sith. If so, it followed that he accepted that Sidious was Vader’s dark side Master. (Tarkin) Grievous did not know. 3.19 lakh rats killed in 7 days? BJP leader Eknath Khadse wants a probe. (File Photo) 3.19 lakh rats killed in 7 days? BJP leader Eknath Khadse wants a probe. (File Photo) In a startling revelation, BJP leader Eknath Khadse alleged Thursday that the company awarded a contract for pest control in the state secretariat has claimed that it killed 3,19,400 rats in seven days. The work order to a private company was given by the General Administration Department of the Maharashtra government, under Chief Minister Devendra Fadnavis. A former minister, Khadse told the Vidhan Sabha there was something rotten which needed a thorough investigation to get to the rats playing hide and seek in government’s headquarters at Mantralaya, the state secretariat. “A company which was given the award for killing rats has claimed it killed 3,19,400 rats within seven days in Mantralaya,” he said. Raising more questions, he said, “Can there be so many rats in Mantralaya? And would it be ever possible to execute such an exercise within seven days.” Dismissing such statistics and claims as bizarre, he said, “The government should conduct a probe in the entire matter.” “The government will probe the matter to ascertain the facts about the company, tender process and job.” “The government will probe the matter to ascertain the facts about the company, tender process and job.” The Brihanmumbai Municipal Corporation has managed to kill six lakh rats in two years in the entire city of Mumbai, he said, which begs the question of where has the private company spotted so many rodents. The GAD issued the work order to the company based on a survey which allegedly said there were 3,19,400 rats in Mantralaya and the company was given six months to get rid of them all. If these statistics are true, it means “They had to kill 45,628.57 rats a day. Now, those 0.57 must be the new born ones,” Khadse said. He also said that it must be a super-efficient company to have been able to kill 31.68 rats every half minute, evoking laughter in the state Assembly. “The total weight of these rats which were killed would be 9,125.71 kg. It would mean one truck would be required to carry the dead rodents and get them disposed.” Strangely, he said, nobody in the Mantralaya had seen this exercise conducted. Unwilling to let the issue go, Khadse wondered why the government did not deploy ten cats to do the job. Now, if they had set the cats loose it would have worked effectively and free of cost, he said. In his reply to a debate on budgetary demands, Maharastra minister of state for GAD, Madan Yerawar said, “The government will probe the matter to ascertain the facts about the company, tender process and job.” BJP MLA Charansingh Waghmare, who sought information on the alleged irregularities under RTI said, “The contract was given to a Labour Society. It was for six months. It was reduced to two months. But the company claimed the work was over within seven days. The bill book shows the work was done within the period between May 3 and May 10, 2016.” He also said, “ There was no tendering process was followed. I have already complained this matter to Chief Minister’s Office. I have sought a probe.” 📣 The Indian Express is now on Telegram. Click here to join our channel (@indianexpress) and stay updated with the latest headlines For all the latest India News, download Indian Express App.In addition to all of the problems Whitaker describes in the linked article—failed diagnostics, failed theories, failed “disease models,” failed treatments, making matters worse for the mentally ill, and drugging children and minors without their consent—I would further submit that our generally accepted model of the human mind itself is as deeply flawed. Rather than starting with the idea that humans have or develop personalities that do or don’t adapt well to some ambiguous social standard, we would do better to start with the idea that humans are fundamentally interactive beings, beings that communicate. If our interactions are good, we will be well enough. If our communications
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6197, 15, 475, 475, 475, 4952, 387, 253, 187, 2606, 672, 4377, 367, 936, 282, 2577, 369, 417, 2568, 253, 14969, 3331, 273, 253, 187, 30574, 952, 13, 1223, 253, 30408, 497, 10054, 1302, 342, 512 ]	part of the history of the Roman empire. While that great body was invaded by open violence, or undermined by slow decay, a pure and humble religion gently insinuated itself into the minds of men, grew up in silence and obscurity, derived new vigor from opposition, and finally erected the triumphant banner of the Cross on the ruins of the Capitol. Nor was the influence of Christianity confined to the period or to the limits of the Roman empire. After a revolution of thirteen or fourteen centuries, that religion is still professed by the nations of Europe, the most distinguished portion of human kind in arts and learning as well as in arms. By the industry and zeal of the Europeans, it has been widely diffused to the most distant shores of Asia and Africa; and by the means of their colonies has been firmly established from Canada to Chili, in a world unknown to the ancients. But this inquiry, however useful or entertaining, is attended with two peculiar difficulties. The scanty and suspicious materials of ecclesiastical history seldom enable us to dispel the dark cloud that hangs over the first age of the church. The great law of impartiality too often obliges us to reveal the imperfections of the uninspired teachers and believers of the gospel; and, to a careless observer, their faults may seem to cast a shade on the faith which they professed. But the scandal of the pious Christian, and the fallacious triumph of the Infidel, should cease as soon as they recollect not only by whom, but likewise to whom, the Divine Revelation was given. The theologian may indulge the pleasing task of describing Religion as she descended from Heaven, arrayed in her native purity. A more melancholy duty is imposed on the historian. He must discover the inevitable mixture of error and corruption, which she contracted in a long residence upon earth, among a weak and degenerate race of beings. [102] [Footnote 102: The art of Gibbon, or at least the unfair impression produced by these two memorable chapters, consists in confounding together, in one undistinguishable mass, the origin and apostolic propagation of the Christian religion with its later progress. The main question, the divine origin of the religion, is dexterously eluded or speciously conceded; his plan enables him to commence his account, in most parts, below the apostolic times; and it is only by the strength of the dark coloring with which he has brought out the failings and the follies of succeeding ages, that a shadow of doubt and suspicion is thrown back on the primitive period of Christianity. Divest this whole passage of the latent sarcasm betrayed by the subsequent one of the whole disquisition, and it might commence a Christian history, written in the most Christian spirit of candor.--M.] Our curiosity is naturally prompted to inquire by what means the Christian faith obtained so remarkable a victory over the established religions of the earth. To this inquiry, an obvious but satisfactory answer may be returned; that it was owing to the convincing evidence of the doctrine itself, and to the ruling providence of its great Author. But as truth and reason seldom find so favorable a reception in the world, and as the wisdom of Providence frequently condescends to use the passions of the human heart, and the general circumstances of mankind, as instruments to execute its purpose, we may still be permitted, though with becoming submission, to ask, not indeed what were the first, but what were the secondary causes of the rapid growth of the Christian church. It will, perhaps, appear, that it was most effectually favored and assisted by the five following causes: I. The inflexible, and if we may use the expression, the intolerant zeal of the Christians, derived, it is true, from the Jewish religion, but purified from the narrow and unsocial spirit, which, instead of inviting, had deterred the Gentiles from embracing the law of Moses. II. The doctrine of a future life, improved by every additional circumstance which could give weight and efficacy to that important truth. III. The miraculous powers ascribed to the primitive church. IV. The pure and austere morals of the Christians. V. The union and discipline of the Christian republic, which gradually formed an independent and increasing state in the heart of the Roman empire. [Footnote!: Though we are thus far agreed with respect to the inflexibility and intolerance of Christian zeal, yet as to the principle from which it was derived, we are, toto coelo, divided in opinion. You deduce it from the Jewish religion; I would refer it to a more adequate and a more obvious source, a full persuasion of the truth of Christianity. Watson. Letters Gibbon, i. 9.--M.] I. We have already described the religious harmony of the ancient world, and the facility [102] with which the most different and even hostile nations embraced, or at least respected, each other's superstitions. A single people refused to join in the common intercourse of mankind. The Jews, who, under the Assyrian and Persian monarchies, had languished for many ages the most despised portion of their slaves, [1] emerged from obscurity under the successors of Alexander; and as they multiplied to a surprising degree in the East, and afterwards in the West, they soon excited the curiosity and wonder of other nations. [2] The sullen obstinacy with which they maintained their peculiar rites and unsocial manners, seemed to mark them out as a distinct species of men, who boldly professed, or who faintly disguised, their implacable habits to the rest of human kind. [3] Neither the violence of Antiochus, nor the arts of Herod, nor the example of the circumjacent nations, could ever persuade the Jews to associate with the institutions of Moses the elegant mythology of the Greeks. [4] According to the maxims of universal toleration, the Romans protected a superstition which they despised. [5] The polite Augustus condescended to give orders, that sacrifices should be offered for his prosperity in the temple of Jerusalem; [6] whilst the meanest of the posterity of Abraham, who should have paid the same homage to the Jupiter of the Capitol, would have been an object of abhorrence to himself and to his brethren. But the moderation of the conquerors was insufficient to appease the jealous prejudices of their subjects, who were alarmed and scandalized at the ensigns of paganism, which necessarily introduced themselves into a Roman province. [7] The mad attempt of Caligula to place his own statue in the temple of Jerusalem was defeated by the unanimous resolution of a people who dreaded death much less than such an idolatrous profanation. [8] Their attachment to the law of Moses was equal to their detestation of foreign religions. The current of zeal and devotion, as it was contracted into a narrow channel, ran with the strength, and sometimes with the fury, of a torrent. [Footnote 102: This facility has not always prevented intolerance, which seems inherent in the religious spirit, when armed with authority. The separation of the ecclesiastical and civil power, appears to be the only means of at once maintaining religion and tolerance: but this is a very modern notion. The passions, which mingle themselves with opinions, made the Pagans very often intolerant and persecutors; witness the Persians, the Egyptians even the Greeks and Romans. 1st. The Persians.--Cambyses, conqueror of the Egyptians, condemned to death the magistrates of Memphis, because they had offered divine honors to their god. Apis: he caused the god to be brought before him, struck him with his dagger, commanded the priests to be scourged, and ordered a general massacre of all the Egyptians who should be found celebrating the festival of the statues of the gods to be burnt. Not content with this intolerance, he sent an army to reduce the Ammonians to slavery, and to set on fire the temple in which Jupiter delivered his oracles. See Herod. iii. 25--29, 37. Xerxes, during his invasion of Greece, acted on the same principles: l c destroyed all the temples of Greece and Ionia, except that of Ephesus. See Paus. l. vii. p. 533, and x. p. 887. Strabo, l. xiv. b. 941. 2d. The Egyptians.--They thought themselves defiled when they had drunk from the same cup or eaten at the same table with a man of a different belief from their own. "He who has voluntarily killed any sacred animal is punished with death; but if any one, even involuntarily, has killed a cat or an ibis, he cannot escape the extreme penalty: the people drag him away, treat him in the most cruel manner, sometimes without waiting for a judicial sentence. * * * Even at the time when King Ptolemy was not yet the acknowledged friend of the Roman people, while the multitude were paying court with all
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946, 28457, 326, 4270, 731, 1108, 326, 253, 1679, 973, 14, 248, 17371, 812 ]	. The trelliswork around the door supports a spindly climber, Mummy holds little Ian – who's one and a half, maybe two? – like a misshapen rugby ball that someone has passed her; and which she wishes she could immediately pass-kick forward, beyond the touchline of maturity. But in place of Daddy, there's just this painted-in glob, this fuzzy outline. Somebody has got at my eidetic memory and retouched it. They've removed Daddy the way that the Stalinist propagandists painted out Trotsky. When Lenin arrived at the Finland Station and mounted the crude, hastily erected rostrum, Lev Davidovich was there. But as Vladimir ranted, Lev, like some Cheshire Cat, began to fade, the planks started to show through his brow; eventually all that was left was a stain. It's the same for the rest of my childhood. At all the Party Congresses that we know Daddy to have attended, he has been negated, erased, excised from the picture. Whether propped against the bonnet of the family Mark 1 Cortina (same birthdate as my own), or sprawled on the sheep-cropped and sheep-bedizened grass around the Chantry, it's the same. Only Mummy and Ian, or Mummy, Ian and maternal relatives – plus this Daddy-absence; this Daddy-vacuity; this Daddy-erasure. I am a big man, like my father. I have his mousy hair and low forehead. I couldn't possibly be said to be ugly, for my features, in themselves, are shapely enough. The cratered dimple in my chin lines up precisely with the scoop out of my top lip and the narrow bridge of my long nose. No, my problem is the same as Daddy's – my features are marooned, set too far in to the middle of my wide face. Furthermore, the way everything falls away at the edges of my face is rather unpleasant. It gives a sodden, lippy impression, like the margin of a peat bog. I have my father's figure as well. Sometimes, when I inadvertently catch sight of myself getting out of the bath, I freeze, startled, and think: Who let that Russian peasant woman in here? But it's only me, because – you see – my hips are wider than my shoulders and my solid legs look as if babies could be squeezed out from their confluence as easily as grapefruit pips. I'm built like a babushka. And another thing, another point of resemblance. When I was a child I was reasonably well co-ordinated, but as I have grown up my sense of body has become both cloudy and diffuse. My fingers and toes are now distant provinces, Datias and Hibernias, cut off for years at a time from the Imperial nervous system. Without The Fat Controller's instruction in the blacker arts of physicality I would undoubtedly have become as hamfisted as Dad was. I certainly look as if I ought to be. If I mention my father at the outset, it is because I want to get his having been out of the way, out of the way. After all nurture has trumped nature a thousandfold as far as my being is concerned. And if I were to see Dad now (I have no idea if he is alive or dead), I should feel compelled to dispose of him. I have no doubt about that. His presence would be an affront to my body; so, for it, there would be the rare delight of extinguishing an imperfect and distressed version of itself, a prototype, a maquette. I should enjoy the bludgeoning of my own features, the pulverising of my own thick bones and the slashing to ribbons of the nauseating congruence of our flesh – more, perhaps, than I've enjoyed any of my other little outrages. Why, oh why, oh whyeeee! Why did Daddy abandon me like that? That's the $64,000 question, that's the Golden Shot. Why didn't he care for me, love me? He must – I am forced to conclude – have been a weakling, an emotional eunuch. That much is certain. He stepped aside and indifferently flicked a wet blanket at the raging bull of paternity. For that I can never forgive him. When I was at university, The Fat Controller saw fit to supplement that version of my father's history that my mother had retailed when I was a child. It is characteristic of The Fat Controller that he should have extemporised in this fashion, dropping bombshells of feeling as casually as crumbs. We were sitting in a café and I recall that he was dunking a doughnut as he spoke, paying no mind to the tea slopping on his cuff, or the granular snowfall on his jacket lapels. 'Your father – Harrumph! A contemptible Essene and no mistakin' – I knew him well, of course.' 'You've never said so before.' 'Well, why should I? I've had no cause to. But now you are about to embark on a career it is only fair that you should know a little more about him. I dare say that your mother always spoke of him as a "brilliant man".' 'She did.' 'Quite so, quite so. Did ye believe her?' 'Well, not entirely, I never saw any evidence of it. While he was at home he never left the sun porch. He sat there all day reading the newspapers. Not even the nationals – he didn't seem to have the gumption to deal with anything much but the local advertiser.' 'And then he went on his pilgrimage, by bus, I believe. He did at least understand this much, that the timetable expresses a set of mutable, quasi-astrological relations, the coming and going of ferrous bodies —' 'Aren't you getting off the point?' 'What point!' he exploded – he could never abide interruption. 'Don't be a booby, sir, you know I will not have a booby for an interlocutor!' 'I'm sorry.' 'Sorry isn't good enough – never is.' We sat in silence for a while. The Fat Controller dunked. I looked on as the customers in an adjacent emporium crammed themselves into unsuitable denims. Eventually The Fat Controller spoke. 'You knew that he was a businessman, of course?' 'Yes, Mum told me that. I assumed that it was something insignificant, perhaps wholesale dry goods.' 'Oh no, you've got it wrong there, boy. You probably can't remember but the furniture your mother had in the bungalow when you were a child came from the old St John's Wood house. It was really quite good, perfectly substantial. It dated from the time when you were very small and your father ran Wharton Marketing.' 'He had his own company then?' 'Absolutely. Your father was one of the most successful marketeers in sixties' London. He had a real flair for it. Knew just how to launch a product, what activities were required, sales promotion or advertising. He had a nice line in statistical interpretation as well.' 'What happened, why did the business fail?' 'Well, people at the time said that it was mismanagement. They pointed to several large accounts that your father had either lost or failed to win, but that was a facile explanation. The truth was that he got bored.' 'Bored?' 'Oh yes – yes indeed. I knew him, as I say. Naturally, for I knew everyone of consequence. I had even done business with him on a number of occasions. I actually went to see him not long before the final collapse. The receivers were champing at the bit, I passed a man with a writ in the vestibule. Your father told me himself: "I just can't be buggered, Samuel," that's what he said, "I can't even summon up the energy to sign a cheque. I can't engage any more." That was the whole explanation, he was subject to a kind of fatal ennui. There was no other reason why the business should have gone down at all.' So my father had retreated into his apathy and my mother moved the family to Saltdean. That much I had known already, and it was because of this that my conscious life began on a cliff. I say a cliff but really the site was more like a monstrous divot, kicked out from some golf course of the gods. On the divot sat the interleaved environs of the twin resorts of Saltdean and Peacehaven. Behind them was the ridge of the South Downs. Their rounded summits had a humanoid aspect, as if they were the grassed-over skulls of long-buried giants. In the lee of the Downs, between Saltdean and Rottingdean, were two contradictory edifices. One was a sprawling red-brick manse, the girls' public school, Roedean. The other was a hideous Modernist joke, the prefiguration of ten thousand bypass-bound corporate compounds, the blind people's home, St Dunstan's. Both establishments were to play a part in my upbringing, a pivotal part. Saltdean and Peacehaven, taken together what did they imply? Well – for the property speculators that built them – that the less well-heeled could
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16182, 323, 10885, 841, 3916, 13, 359, 3091, 760, 4098, 253, 12601, 8, 16066, 1617, 595 ]	"bc_pipe"); } @Override public String preferredName() { return "bc_pipe"; } @Override public int priority() { return -10; } @Callback(doc = "function():string -- Returns the type of the pipe.") public Object[] getPipeType(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipeType().name()}; } catch (Throwable ignored) { } return new Object[]{null, "none"}; } @Callback(doc = "function(side:number):boolean -- Returns whether the pipe is connected to something on the specified side.") public Object[] isPipeConnected(final Context context, final Arguments args) { try { return new Object[]{tileEntity.isPipeConnected(ForgeDirection.getOrientation(args.checkInteger(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(color:string):boolean -- Returns whether the pipe is wired with the given color.") public Object[] isWired(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().isWired(PipeWire.valueOf(args.checkString(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(color:string):boolean -- Returns whether the wired with the given color is active.") public Object[] isWireActive(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().isWireActive(PipeWire.valueOf(args.checkString(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(side:number):boolean -- Returns whether the pipe has a gate on the specified side.") public Object[] hasGate(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().hasGate(ForgeDirection.getOrientation(args.checkInteger(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } } } books.google.com - Hammer (forensic nursing, Quinnipiac University) et al. present a textbook in the new field of forensic nursing, which has come to the forefront in the wake of rising violence. Nurses, crime and forensics experts, and scholars from the US offer 27 chapters on theoretical foundations, the epidemiology...https://books.google.com/books/about/Forensic_Nursing.html?id=_FVrAAAAMAAJ&utm_source=gb-gplus-shareForensic Nursing Forensic Nursing: A Handbook for Practice Hammer (forensic nursing, Quinnipiac University) et al. present a textbook in the new field of forensic nursing, which has come to the forefront in the wake of rising violence. Nurses, crime and forensics experts, and scholars from the US offer 27 chapters on theoretical foundations, the epidemiology of violence, collaboration within disciplines, eQ: Responsive design not working on heroku deployed rails app? I recently deployed a rails app onto: http://secret-brook-8909.herokuapp.com/ I intended it to look on the iphone 4s to look like it would using: http://responsive.victorcoulon.fr/ If you look at the stylesheet of my rails app you will actually see that i hardcoded all the widths of the containers to be 320px. But when I open it on my browser on my iphone it looks like its being opened on a larger resolution screen. Additionally, on the iPhone if you click the profile button, the button doesn't look the same as it does on a normal browser. What can I do to fix these issues? A: you need to add a viewport declaration on the head of the document <meta name="viewport" content="width=device-width, initial-scale=1.0"> Q: Custom alignment of columns in align environment I need to typeset two columns of equations, each row typeset with an equation number to the right as with an ordinary equation. The first column must be centered, and the second column must be left-aligned. There will be many rows, so it must automatically break at a page break as appropriate. There are plenty of related questions, but I can't find any existing solutions that will let me do exactly what I want. (It's a real pain the align environment can't take optional column alignment specifiers.) A: Making align break across pages is simple: add \allowdisplaybreaks[1] to your preamble. And since your first column is text, it's also trivial to center it within align: just wrap it in a \makebox larger than all the images (which centers its contents) and use align as normal. \documentclass{article} \usepackage{amsmath} \allowdisplaybreaks[1] \newcommand{\centerdia}[1]{\makebox[2in]{\includegraphics{#1}}} \begin{document} \begin{align} \centerdia{dia1} & c=20x^2+5x-10+\frac{x^3-4x^2+500x-f(240)}{50} \\ \centerdia{dia2} & \mu=10\epsilon\\ \centerdia{dia3} & \mu=10\epsilon \end{align} \end{document} A: Use a modified version of align; change 2\tabcolsep into the separation you prefer. \documentclass{article} \usepackage{amsmath,environ} \makeatletter \NewEnviron{specialalign} {\def\align@preamble{% &\hfil \strut@ \setboxz@h{\@lign$\m@th\displaystyle{####}$}% \ifmeasuring@\savefieldlength@\fi \set@field \hfil \tabskip2\tabcolsep &\setboxz@h{\@lign$\m@th\displaystyle{{}####}$}% \ifmeasuring@\savefieldlength@\fi \set@field \hfil \tabskip\alignsep@ }% \begin{align}\BODY\end{align}} \makeatother \begin{document} \begin{specialalign} x & a=b \\ yyy & c=d+e+f \\ zzzzzz & 1\ne0 \end{specialalign} \end{document} 76 B.R. 1001 (1987) In re Louis FLEET, Debtor. Louis FLEET, Sarah Morrison, Philadelphia Unemployment Project on behalf of themselves and all others similarly situated, Plaintiffs, v. UNITED STATES CONSUMER COUNCIL, INC., Jack Rhode, Betty Rosi, Deborah Tavares, Defendants. Bankruptcy No. 81-04969K, Adv. No. 83-0880K. United States Bankruptcy Court, E.D. Pennsylvania. August 18, 1987. 1002 1003 Wayne Powell, Barry J. Hockfield, Cherry Hill, N.J., for defendants. Henry J. Sommer, Gary Klein, Community Legal Services, Philadelphia, Pa., for plaintiffs. Edward Sparkman, Philadelphia, Pa., Trustee. OPINION DAVID A. SCHOLL, Bankruptcy Judge. A. INTRODUCTION Presently before us in this long-outstanding proceeding is a Motion for Class Certification by the Plaintiffs. We reject the Defendants' principal argument that the Motion should be denied because it was not filed until the case was over four years old, holding that any unfair prejudice arising from the Plaintiffs' delay is, for the most part, cured by our further holding that the default entered against the Defendants does not extend in its effect to unnamed class members. We also reject the Defendants' arguments that the elements of commonality or adequacy of representation are lacking and find all of the prerequisites to maintain a class action set forth in Federal Rule of Civil Procedure (hereinafter referred to as "F.R.Civ.P.") 23(a) present. However, we also hold that the fact that the Defendants are no longer doing business renders the only practical relief for unnamed class members to be strictly monetary relief. Therefore, we conclude that the matter may be maintained as a class action pursuant to F.R.Civ.P. 23(b)(3) only. Since the Plaintiffs have not addressed the issues of provision and cost of notice to unnamed class members, pursuant to F.R. Civ.P. 23(c)(2), or their proposed methodology for handling these claims, we shall only grant the Plaintiffs' Motion conditionally
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7723, 3293, 704, 86, 18810, 6531, 425, 5043, 17113, 254, 13, 6531, 425, 5043, 448, 14064, 343, 13, 6531, 22870, 16477, 66, 47324, 15, 1623, 425, 458, 41199, 7222, 15, 308, 483, 479, 16465, 572, 8, 251, 425, 458, 41199, 7222, 15, 535, 795, 6800, 80, 13, 9568, 21728, 860, 1061, 9309, 265, 353, 1278, 460, 13, 7460, 24932, 30667, 261, 13, 50276, 187, 11095, 43596, 13, 1061, 826, 7667, 24763, 919, 20887, 267, 16974, 3333, 187, 187, 53, 483, 2636, 572, 8, 300, 340, 247, 4057, 8041, 250, 795, 615, 2636, 260, 25890, 860, 64, 479, 5586, 47630, 24229, 313, 16853, 618, 261, 2636, 572, 8, 300, 278, 8, 257, 820, 24690, 442, 372, 1061, 2146, 41057, 13, 4057, 1666, 458, 10538, 400, 30071, 490, 720, 13, 458, 1111, 860, 3760, 30071, 2192, 6457, 1405, 372, 2636, 1753, 5139, 362, 4631, 3974, 68, 363, 250, 11565, 11737, 1670, 2310, 13, 295, 8, 383, 14, 336, 7222, 13, 1753, 5139, 298, 8, 32839, 6606, 582, 479, 5586, 47630, 24229, 795, 4123, 32563, 2241, 4688, 1079, 64, 277, 8, 328, 15451, 255, 372, 448, 4863, 7460, 13, 480, 8, 257, 2410, 44209, 13, 247, 16547, 860, 11565, 23571, 256, 8, 383, 771, 18279, 860, 546, 16547, 386, 1162, 7460, 13, 1061, 18880, 13, 11329, 251, 24346, 13, 269, 3525, 1659, 440, 7204, 347, 339, 91, 354, 10050, 4057, 440, 41806, 15451, 255, 372, 448 ]	que tu me dis toujours tout ce que tu penses, et que près de moi quand je te le dis, tu as raison de ne prendre ombrage de rien. Je puis naturellement me tromper. Tu me diras. Aucune nouvelle de Gaffé, d'ailleurs, ni de l'acheteur possible du Derain (ce dernier ne répondra que dans huit jours). Voilà. Et je ne t'ai rien dit de toi. Mais c'est presque assez, n'est-ce pas, que je t'aie parlé ainsi. Toi seule, à ta place, peux m'entendre. Vous savez que je ne vois clair qu'en vous regardant Je ne suis pas très intelligent pas très bon pas très fort et je ne suis même grand-chose que le matin, en m'éveillant, quand je tiens vos deux petites mains dans la mienne. André _Par exprès_ _Enveloppe : Madame André Breton, Chez Madame Georges Lévy,_ _12, quai Saint-Nicolas, Strasbourg (Bas-Rhin)_ _Cachet de la poste : 9-11-26_ ✩ ## _Carte postale_ D'arche en arche, du plus loin au plus près, je pense à ma petite Simone bien-aimée. André _Carte postale : Blackfriars Bridge, London_ _Adressée à Madame André Breton,_ _42 rue Fontaine, Paris, France_ _Cachet de la poste : 24-5-27_ ✩ ## _Sur papier à en-tête de_ LA RÉVOLUTION SURRÉALISTE _Paris, le 29 juillet 1927_ Mon petit chéri, je suis las, très las. Tu sais, tu m'accorderas que ma pauvre vie d'imbécile ou de voyou se passe à ne pas m'attendre à presque tout ce qui m'arrive, à m'attendre aussi à ce qui n'arrive pas. Je ne m'attendais à rien moins qu'à ce départ, enfantillage d'abord, comment ne le considérerais-je pas ainsi ?, grave et _dur_ rappel à l'ordre ensuite. Toi partir ? Je ne pleure pas non plus. Je suis calme. Toi partir ! Mon cher petit, de quoi s'agit-il donc ? Que fuis-tu ? Comme je l'avais vaguement senti hier au téléphone, il a donc suffi d'un jour ou deux pour que tu t'éloignes de toute cette distance qui avait été supprimée une fois pour toutes, je croyais ? Impossible, avec la meilleure volonté, de prendre au sérieux le prétexte que tu me donnes : ces propos tenus, en pensant à je ne sais quoi mais pour sûr, pas à nous. Insister sur ce point m'écœurerait. _Pas à nous_ : je le jure. À toi ? Comment même as-tu pu l'entendre ainsi ? Il faudrait que je sois devenu une belle brute, tout de même. C'est ma faute, d'ailleurs. À quoi pensais-je ce soir-là ? Quel mauvais esprit m'animait ? Je meublais sans doute à grands frais une conversation qui me paraissait languir, comme toujours, je m'ennuie tant, je voudrais que les gens aient des langues de feu. Mettons que je sifflais comme une sale vipère que je suis parfois, oui, quand telle ou telle chose m'a trop dégoûté. J'étais très malheureux et voilà tout. De là à te faire de la peine, à toi si noble et même ce que je sais de plus noble ( _naturellement_ ) et de plus pur, et de plus compréhensive aussi, ma chère petite Simone – mais non je ne faisais pas exprès ce n'est pas vrai. Je suis quelquefois _malheureux_ avec une effroyable conscience de ce malheur. Mais c'est déjà trop revenir sur ces propos misérables, idiots et creux du reste si tu veux bien y songer, tout à fait indignes de mon intelligence au moins. Simone : de mon intelligence. Le mal est peut-être plus grand. Tels qu'ils étaient ces propos, ils sont venus à l'appui d'une idée que tu te formais depuis déjà longtemps : à savoir sans doute qu'un péril qui n'est pas négligeable continuait à planer au-dessus de moi, de moi tel que tu me vois, que tu me connais... L'immense générosité dont, en l'occurrence, tu as toujours fait preuve ne m'échappe pas, tu sais. Ce n'est pas beaucoup dans les moyens humains, je me le dis depuis longtemps et chaque jour. Tout à coup tu ne t'en sens plus capable, – pardon, ma chère petite enfant. Il faut absolument qu'ici je parle un peu de moi. J'ai beaucoup de peine à le faire. Il faut que je me force. Lassitude, confusion, découragement tu ne peux savoir tout ce qui s'y oppose. Mais je te le dois mille fois. ... _De ce côté_ si étrange, tu sais presque tout ce qui le fait si étrange, pour moi si terriblement pathétique, oui : il est ainsi. Je ne t'ai jamais rien caché. Je ne suis absolument pas guéri. Si « guérir » il y a. Pardon pour les mots ignobles. Tout ce qu'il y a de bouleversant pour moi à regarder _de ce côté_ existe toujours, et n'a pas changé. Je voudrais dire le contraire que je ne le pourrais pas. Je suis toujours hanté. « L'amour-folie » dis-tu : ce n'est pas sûr. Le mystère simple, à portée de la main. Rien qui différencie cela du trouble que causaient par exemple les « sommeils ». C'est un peu plus fort, et voilà tout. Je ne suis pas M. Maurice de Fleury, je ne crois pas et c'est peut-être mon seul tort, je ne crois pas à la nécessité de me soigner. Il se peut, je l'ai déjà dit et j'en ai peur, que ce ne soit pas, du reste, l'amour. C'est, au moins pour une si grande part, le résultat d'une culture infiniment particulière, tu le sais, de la _déception_. Une véritable perversion du goût en a été chez moi la conséquence. Rien d'absolument électif, peut-être, ne m'attire vers Lise (enfin je ne sais pas) mais c'est comme si j'avais été en même temps qu'elle, quoique tout différemment, victime d'un accident jadis. Ce n'est pas cela. En toute loyauté je ne crois pas que je devrais la fuir comme toi si simplement tu me fuis. C'est comme si l'on allait se cacher la tête dans les feuilles pour ne plus penser, pour ne plus chérir, pour faire disparaître. On ne le doit pas. Tout me dit qu'on ne le doit pas. _Logo, réalisé par Georges Malkine, qui sera repris, plus tard, par la Galerie surréaliste._ Tout ce qu'il y a à attendre _de ce côté_ me paraît être (tu sais ce qu'il m'en coûte de parler ainsi, à bas le positivisme abject, le matérialisme infâme de ce que je vais écrire mais tu veux, n'est-ce pas, que je l'écrive), me paraît être _la résolution fatale_ d'un état de choses qui, j'en conviens, a duré mais aussi s'est modifié en durant et qui, par suite, selon moi, fera place un jour assez prochain à un autre état de ch
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79, 19085, 15, 733, 310, 2834, 281, 2096, 253, 21546, 533, 253, 28145, 403, 627, 15, 688, 247, 2419, 247, 5938, 285, 4475, 9059, 13, 3819, 15, 329, 11179, 3249, 12060, 13, 247, 5253, 13471, 15, 49226, 310, 11790, 285, 253, 4475, 310, 14004, 15, 2064, 24307, 13, 326, 23057, 15, 380, 4181, 326, 11359, 5675, 15, 733, 310, 2834, 281, 37240, 253 ]	xsi:schemaLocation="http://maven.apache.org/POM/4.0.0 http://maven.apache.org/xsd/maven-4.0.0.xsd"> <parent> <artifactId>zuihou-authority</artifactId> <groupId>com.github.zuihou</groupId> <version>c.2.5.1-SNAPSHOT</version> <relativePath>../</relativePath> </parent> <modelVersion>4.0.0</modelVersion> <artifactId>zuihou-authority-entity</artifactId> <name>${project.artifactId}</name> <description>权限服务实体模块</description> <dependencies> <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-common</artifactId> <version>${zuihou-project.version}</version> </dependency> <!-- databases 只有权限服务需要引用，其他服务放在server模块 --> <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-databases</artifactId> <optional>true</optional> <scope>compile</scope> </dependency> <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-injection-starter</artifactId> </dependency> <dependency> <groupId>com.baomidou</groupId> <artifactId>mybatis-plus-annotation</artifactId> </dependency> <dependency> <groupId>cn.afterturn</groupId> <artifactId>easypoi-annotation</artifactId> </dependency> <dependency> <groupId>cn.afterturn</groupId> <artifactId>easypoi-base</artifactId> </dependency> </dependencies> </project> Appropriate application of information from biodiversity databases is critical when investigating species distributions and diversity: a comment on Dallas et al. (). Using data from biodiversity informatics resources, Dallas et al. (Ecol. Lett., 20, 2017, 1526-1533) suggested limited relationships between climate and local abundance among several taxonomic groups. Investigation of a subset of these data suggests that their results may be misleading due to inappropriate application of the biodiversity data.Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase. Folinic acid (leucovorin, [LV]) can potentiate the growth inhibitory effects of fluorouracil (5-FU) in vitro and in vivo. LV is a precursor for 5,10-methylene-tetrahydrofolate (CH2-THF). Sufficient levels of CH2-THF enhance the inhibition of the enzyme thymidylate synthase by the 5-FU metabolite FdUMP. This study describes the effects of 5-FU and LV in two murine (C26-10, C38-1) and two human (WiDr, HT-29) colon carcinoma cell lines and in two murine tumors (Colon 26 and Colon 38). In vitro, only C38-1 was more sensitive for the combination of LV/5-FU compared with 5-FU alone. This effect was not dose or schedule dependent. l-LV, a purified stereo-isomere of LV, is thought to be the biological active form. Tests with this compound in vitro did not show a better effect than the mixture of d- and l-LV. In vivo, dl-LV could potentiate 5-FU antitumor effect in two murine colon tumors (Colon 26, Colon 38). This effect was clearly schedule dependent. dl-LV administered 1 hour before and together with 5-FU was much better than only simultaneous or posttreatment, but there was no dose dependency, while like in vitro l-LV effect was comparable to dl-LV. TdR was used to study the role of TS inhibition in the growth inhibitory effect of 5-FU with and without LV. TdR can reverse growth inhibition caused by TS inhibition due to 5-FU. In vitro, a partial reversal of growth inhibition of 5-FU and 5-FU/LV was observed, but in vivo there was no reversal. In vivo, TdR combinations led to high toxicity. Measurements of TS amounts in cells and tumors showed that those of human origin had much lower TS than the murine. C38-1 and Colon 38 with low TS were more sensitive to 5-FU than Colon 26 with higher TS amounts. TS inhibition was studied in the two murine colon tumors at several time points after weekly 5-FU or LV and 5-FU administration. LV did not increase the extent or retention of TS inhibition due to 5-FU during the first week. After three courses of treatment a fourfold increase of TS levels was seen in Colon 26 after 5-FU therapy. This resulted in a less effective TS inhibition after this treatment. Tumors treated with 5-FU and LV also showed an increase of TS, but to a lower extent, while the effect on TS inhibition remained the same.(ABSTRACT TRUNCATED AT 400 WORDS)Here comes a new Episode in the "Learning English Is Fun™" Alphabet Learning Series for Preschool Children by ChuChu TV DEF Songs Compilation… Here comes a new Episode in the "Learning English Is Fun™" Alphabet Learning Series for Preschool Children by ChuChu TV DEF Songs Compilation Letter D Song - 01:23 Letter E Song - 04:33 Letter F Song - 08:29 In this episode, ChuChu & Friends will teach your little ones about the alphabets D,E,F by travelling to the alphabet world in their toy train. Make your kids enjoy and learn with ChuChu TV. Please like and share this video. Thank You! =============================================== Video: Copyright 2017 ChuChu TV® Studios Music and Lyrics: Copyright 2017 ChuChu TV® Studios ChuChu TV ®, Cutians ®, all the characters and logos used are the registered trademarks of ChuChu TV Studios =============================================== The NEW Numbers Song \| Learn To Count from 1 to 10 \| Number Rhymes For Children \| ChuChu TV for Kids 00:07 The New Numbers Song 02:23 Mont… The NEW Numbers Song \| Learn To Count from 1 to 10 \| Number Rhymes For Children \| ChuChu TV for Kids 00:07 The New Numbers Song 02:23 Months of the Year Song 06:14 The Taste Song 07:53 Pineapple Song 09:44 Snap Snap Snap Actions Song 11:42 The Grow Grow Song 13:25 Going To the Forest 21:32 Three Little Kittens Went To The Theme Park – Cutians 24:32 Three Little Kittens Went To The Fair – Cutians 27:31 Three Little Kittens Went To The Beach – Cutians 30:33 Three Little Kittens Went Out To Eat – Cutians 33:00 Three Little Kittens Played Games at Rio – Cutians Click here to Subscribe to SetIndia Channel : https://www.youtube.com/user/setindia?sub_confirmation=1 Click to watch all the episodes of Crime … Click here to Subscribe to SetIndia Channel : https://www.youtube.com/user/setindia?sub_confirmation=1 Click to watch all the episodes of Crime Patrol Dial 100 - https://www.youtube.com/playlist?list=PLzufeTFnhupzBi22rTZgQbnRMWVCrUEvP Episode 601: -------------------- The occupants of a working women's hostel complain about a man entering their rooms when they are asleep. The hostel warden assures them that she will take action against the culprit and soon assembles all the male staff in the institution. The warden warns the staff that her eyes will now be on all of them. A few days later, one of the complainants, Pooja Agarwal, is found murdered in the restroom of the hostel. Meanwhile, Rajeev the hostel caretaker is found missing and the police go on Rajeev's trail. Is Rajeev the real culprit? Find out! Crime Patrol Dial 100: ----------------------------------- Crimes that tell us, we need to be careful, we need to be watchful. Crimes that tell us lives could have been saved.Every crime we hear of, either warns us to be careful or scares us, it could happen to us. Every crime ignites a feeling, 'It should not have happened'.Would knowing the 'Why' behind a crime, help in stopping a crime from happening?'I don’t like the way he looks at me', 'I don’t like the way he/she is behaving', 'I think he/she is out of his/her mind', 'I think he/she has gone crazy'. That gaze, that quirky smile, that persistent stare which unnerves. It is difficult to understand the intentions but the hints are there.In a house a husband and wife argue, fight. A vessel comes flying, a glass breaks. Husband is angry and the wife is upset. That hatred, that ego. The distance that keeps growing. It is difficult to comprehend the
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253, 378, 15, 36, 15, 41172, 5439, 247, 2264, 273, 670, 370, 805, 15, 21, 14, 24561, 275, 3569, 23866, 1108, 370, 21, 15, 22, 14, 24561, 432, 4292, 285, 370, 24, 15, 26, 14, 24561, 432, 18674, 15, 380, 1781, 10459, 23866, 5257, 281, 6427, 253, 954, 4116, 13, 533, 16612, 1346, 403, 2403, 6832, 23866, 342, 4577, 13, 533, 10879 ]	uliformi subcylindrica v. leviter infundibuliformia, costis 2 prominentibus, peristomio operculum versus acuto v. acuminato, expanso, 8-35 mm lato, costis 1/2-1 mm distantibus, dentibus c. tam longis quam latis ; operculo rotundato-cordato, facie inferiore plano v. plica subcarinato ; inflorescentia racemus longus pedicellis inferioribus c. 20 mm longis omnibus 2-floris ; indumentum in partibus vegetativis subnullum, in inflorescentiis densum adpressum, e pilis stellatis compositum. References Further reading Mansur, M. 2001. In: Prosiding Seminar Hari Cinta Puspa dan Satwa Nasional. Lembaga Ilmu Pengetahuan Indonesia, Bogor. pp. 244–253. Marwinski, D. 2014. Eine Expedition nach West-Papua oder auf den Spuren von Nepenthes paniculata. Das Taublatt 78: 11–44. Meimberg, H., A. Wistuba, P. Dittrich & G. Heubl 2001. Molecular phylogeny of Nepenthaceae based on cladistic analysis of plastid trnK intron sequence data. Plant Biology 3(2): 164–175. Meimberg, H. 2002. Ph.D. thesis, Ludwig Maximilian University of Munich, Munich. Meimberg, H. & G. Heubl 2006. Introduction of a nuclear marker for phylogenetic analysis of Nepenthaceae. Plant Biology 8(6): 831–840. Renner, T. & C.D. Specht 2011. A sticky situation: assessing adaptations for plant carnivory in the Caryophyllales by means of stochastic character mapping. International Journal of Plant Sciences 172(7): 889–901. External links Photographs of N. insignis insignis Category:Carnivorous plants of Asia Category:Flora of Western New Guinea Category:Endemic flora of New Guinea Category:Threatened flora of Asia Category:Plants described in 1928 Category:Vulnerable plantsGenetic role of rat macrophage cytotoxicity against tumor. Macrophages from the Lewis (Le) rat strain are significantly more cytotoxic to a Moloney sarcoma tumor both in vivo and in vitro, than are macrophages from the Brown Norway (BN) strain. Activity of macrophages from (Le x BN)F1 rats that are histocompatible with the Moloney sarcoma tumor is directed toward tumor and/or virus-associated antigens and is expressed as a dominant genetic trait. Experiments with backcross rats suggest that the genetic factors are unrelated to the major histocompatibility locus (AgB) of the rats. BN microphages, although not active against tumor and/or viral antigens, can become cytotoxic to cells displaying Le alloantigens.Cyclea elegans Cyclea elegans is a species of flowering plants in the family Menispermaceae. It is found in Sumatra, Malaya, Borneo. An isotype is kept at Kew Gardens Herbarium. It was collected on Mount Kinabalu Dallas. References Other references Ridl. in Fl. Mal. Pen. 1922: 115 Burk. & Hend. Gard. Bull. S. S. 1925: 344 Yamamota J. Soc. Trop. Agric. 1944: 145 Yamamoto J. Soc. Trop. Agric. 1944: 145 Forman Kew Bull. 1960: 71 Heine Fedde, Rep. 54. 1951: 227 Diels Pfl. R. 1910: 311 Airy Shaw Kew Bull. 1940: 538 External links Cyclea elegans at Flora Malesiana Category:Plants described in 1889 Category:Flora of Borneo Category:Flora of Malaya Category:Flora of Sumatra elegansQ: React, best way to deal with fetching when navigating between routes containing same component Basically, I would like to fetch the latest data every time user navigates to different tab. For example, I have summary page and details page for customers, which both includes the same customers container component. I'm doing my initial fetching in componentDidMount function, which doesn't get triggered in route change, as component stays in the DOM. Component necessarily doesn't receive new props either. One solution would be to customize router link with fetch action being dispatched based on the href, but I'm pretty sure this is an anti-pattern, as it complicates code a lot, is hard to maintain, mixes concerns, and may result in a double fetch if target route didn't contain the component already. Does React provide any lifecycle hook or mechanism that allow me to fetch in response to navigation event alone? I'm using React-router-component and Redux. A: As far as I understand both tabs happen to contain the same component and so React re-uses the DOM and doesn't create a new component instance, right? You can use React's special key prop to force React to replace a specific instance. E.g.: <div className="tab-content> <div key="tab-1" className="shared-component-across-tabs"> shared-component-across-tabs </div> </div> And in the second tab you'd use key="tab-2". Otherwise your route handler component will receive props.location.pathname from the router. You can also implement componentWillReceiveProps and check if the pathname has changed and re-fetch the data in that case. using N2; using N2.Details; using N2.Integrity; using N2.Templates.Items; using N2.Web.UI.WebControls; using N2.Definitions; using N2.Web.UI; namespace N2.Templates.Items { [PartDefinition("Social bookmarks", IconUrl = "~/Templates/UI/Img/digg.png")] [RestrictParents(typeof(IPage))] [AllowedZones(Zones.SiteRight, Zones.Right, Zones.RecursiveRight, Zones.SiteLeft)] [RestrictCardinality] [FieldSetContainer("SocialTargets", "Social buttons for", 100)] public class SocialBookmarks : AbstractItem { [EditableCheckBox("Facebook", 100, ContainerName = "SocialTargets")] public virtual bool Facebook { get { return GetDetail("Facebook", true); } set { SetDetail("Facebook", value, true); } } [EditableCheckBox("Google+1", 110, ContainerName = "SocialTargets")] public virtual bool GooglePlus1 { get { return GetDetail("GooglePlus1", true); } set { SetDetail("GooglePlus1", value, true); } } [EditableText(SortOrder = 110)] public override string Title { get { return base.Title; } set { base.Title = value; } } [EditableCheckBox("Like whole site", 120, HelpTitle = "This setting will make it so the whole site rather than the currently displayed page is liked")] public virtual bool LikeSite { get { return GetDetail("LikeSite", true); } set { SetDetail("LikeSite", value, true); } } protected override string TemplateName { get { return "SocialBookmarks"; } } } } It was more than 20 years ago that the B.C. Liberal Party, then in opposition, attacked the NDP government of the day for bestowing special favour upon its "friends and insiders." After 16 years in power, however, the Liberals are entrenched in defending a political fundraising system that sells access and influence to its own friends and insiders. As early as this week, the B.C. Liberal government will acknowledge demands for campaign finance reform with legislation to improve disclosure of those contributions. Unless they divert wildly from the script laid down by Premier Christy Clark, the bill will not curb the lucrative business of trading cash for access. A Globe and Mail investigation on Saturday revealed that lobbyists and government consultants, paid by corporations or special-interest groups to try to influence politicians, are milked by the party in power for multiple donations in exchange for a retailed commodity: Access to the Premier and members of her cabinet. Story continues below advertisement Globe Investigation: How B.C. lobbyists are breaking one of the province's few political donation rules Related: Elections B.C. probes Liberal Party fundraising Gary Mason: Global ridicule won't stop B.C. Liberals' deceitful financing extravaganza In 2016, the B.C. Liberals raised a total of about $12.4-million in political donations – $4.5-million from individuals and $7.9-million from corporations. The large corporate donations tend to attract the most attention, but lobbyists are making substantial donations with smaller, but frequent
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50274, 17, 50274, 1235, 50274, 3439, 15, 361, 50275, 2950, 15, 361, 187, 50276, 12481, 4050, 50254, 252, 50264, 50276, 2405, 50254, 21, 50265, 25, 50274, 21, 50274, 23, 50274, 3680, 50274, 3357, 15, 1857, 50275, 2950, 15, 2417, 187, 50276, 998, 10092, 434, 8896, 4775, 5197, 50254, 50254, 50254, 50266, 50274, 187, 50276, 43756, 4332, 50254, 50254, 24, 50254, 20, 50265, 20, 50274, 18, 50274, 17, 50274, 1012, 50274, 22, 24677, 50274, 2950, 15, 1010, 187, 50276, 18, 50, 4050 ]	had “blood all over” telling him she had had a miscarriage. He said he helped clean up the blood and flushed what he now knew to be the placenta down the toilet. ‘Cause unascertained’ When asked by the coroner how his daughter ended up in Bluebell Woods he replied: “Because she put her there. “No-one else knew about her daughter.” Pathologist Dr Charles Wilson told the inquest he did not believe Pearl’s body had been at the woodland for long because decomposition would have been greater. The medical cause of death was unascertained. Recording a narrative verdict, Manchester North senior coroner Joanne Kearsley concluded Pearl was delivered on 25 December 2017 at between 32 and 40 weeks in a viable pregnancy but because of decomposition it was not possible to know whether she was born alive or stillborn. She added her delivery was concealed and she was stored in an unknown place until or around 4 April.Authors Abstract The optimal choice of sites to make spatial prediction is critical for a better understanding of really spatio-temporal data. It is important to obtain the essential spatio-temporal variability of the process in determining optimal design, because these data tend to exhibit both spatial and temporal variability. Two new methods of prediction for spatially correlated functional data are considered. The first method models spatial dependency by fitting variogram to empirical variogram, similar to ordinary kriging (univariate approach). The second method models spatial dependency by linear model co-regionalization (multivariate approach). The variance of prediction method was chosen as the optimization design criterion. An application to CO concentration forecasting was conducted to examine possible differences between the design and the optimal design without considering temporal structure.A French housewife found guilty of sexually abusing two plumbers who had visited her house to mend a leak today has apologised to the men. Identified only by her initials of I.D, the 50 year old said she was determined to turn over a new leaf and become a life coach. On Wednesday a court in Arras, northern France, found her guilty of abusing the men when they visited her flat in October last year. The 50-year-old French housewife made lewd suggestions to a pair of plumbers and rubbed up against their bottoms. When they resisted her advances she reacted furiously, smacking one of them across the face Rather than allowing them to get on with their work, she forced herself against their bottoms when they were bending over, and made lewd suggestions. ‘When you have done with the radiators, come to my bed,’ was one of her suggestions, the court heard. The men were not interested in sex, but that did not stop the women closing the shutters of her flat and making further propositions. When shunned further, the woman smacked one of the men across the face, before throwing them both out of her home, Voix du Nord newspaper reported. In their panic, the men left their tools behind, leaving the police to retrieve them the next day. The woman, who had a serious alcohol problem, also attacked police officers. She was given a 12 month suspended prison sentence and told to seek treatment for her heavy drinking. I.D. told the court: ‘I’ve now decided to take my life in hand. I’ve not drunk for more than eight months, and I’ve started training to be a life coach.’Background ========== In the United States and many Western nations, the need for containment of health care costs is rising \[[@B1]\]. Between 2000 and 2010, increases in per capita health care expenses reached 71.9 percent in the United States, 76.4 percent in Canada, 61.9 percent in Germany, and 87.2 percent in the United Kingdom. Expenses were substantially higher in the United States than in the other nations throughout this period \[[@B2]\]. Recent discussions concerning containment of health care expenditures have generated a high level of interest in connecting a portion of provider reimbursement to outcomes indicators such as hospital inpatient readmissions and complications \[[@B3]\]. In this context, hospital readmissions have generated considerable attention. Reduction of readmissions holds the potential for elimination of large numbers of inpatient hospitalizations and the payments associated with them \[[@B4],[@B5]\]. Further payer revenue could be generated through financial penalties for excess readmissions by providers whose rates could not be reduced. The Medicare program has already developed and implemented financial penalties based on excess readmission levels \[[@B3],[@B6]-[@B8]\]. This increased interest in hospital outcomes has supported the need for clear and useful clinical definitions and designations of patients who are readmitted. Historically, these patients have frequently been identified by the principal diagnosis of the initial admission that preceded the readmission, such as heart failure, pneumonia, or acute myocardial infarction \[[@B9],[@B10]\]. Such designations are necessary for effective identification and management of these patients. The potential for developing such definitions has also been supported by the development of computerized algorithms to track and evaluate readmissions using provider data \[[@B11]\]. This brief report focused on evaluation of clinical definitions and designations of patients who are readmitted to hospitals. Through data from hospitals in one community, it evaluated examples of two major diagnoses of these patients and suggested implications for their management. The study involved readmissions in the hospitals of Syracuse, New York. These acute care facilities, with 2012 inpatient discharges excluding well newborns, include Crouse Hospital (20,715), St. Joseph's Hospital Health Center (25,743), and Upstate University Hospital (27,600). The primary and secondary acute care service area for these hospitals includes a population of approximately 575,000. The combined hospitals also serve as the tertiary referral center for the eleven county Central New York Health Service Area with a population of 1,405,221 (New York Statistical Information System, 2012). Historically, the Syracuse hospitals have employed a combination of cooperation and competition to improve health care efficiency and outcomes in the service area. A number of cooperative efforts have been developed through the Hospital Executive Council, the collaborative planning organization for the hospitals \[[@B12]\]. This study was developed through a partnership between the Hospital Executive Council and 3 M™ Health Information Systems. It involved analysis of hospital readmissions in the Syracuse hospitals during a two year period using the 3 M™ HIS Potentially Preventable Readmissions software \[[@B13]\]. Findings ======== Provider studies of patients readmitted to hospitals has frequently identified these patients by the principal diagnosis of the initial admission that preceded the rehospitalizations. This approach has frequently caused efforts to manage these outcomes to be based on that diagnosis. This designation has also been reflected in Medicare's readmission payment methodology, the first phase of which involved patients with initial admissions for heart failure, pneumonia, and acute myocardial infarction \[[@B14],[@B15]\]. In order to evaluate the effectiveness of this approach to identifying patients who are subsequently readmitted, two of these populations were evaluated in the Syracuse hospitals. Patients with a principal diagnosis of congestive heart failure (APR DRG 194) and pneumonia (APR DRGs 138--139) are two diagnoses frequently associated with these patients. Both diagnoses were used to identify patients in the Medicare readmissions program. For patients with each of these APR DRGs on initial admission, data identifying readmission APR DRGs for each of the three Syracuse hospitals were generated for January-December 2011 and 2012. Combined data for the three hospitals were also identified. The analysis focused on comparison of readmission APR DRGs with initial admission APR DRGs for each hospital by year and quarter during the two year period. The first section of the analysis involved comparisons of initial and readmission diagnoses for patients with an initial admission for heart failure during the two year period. Relevant data are summarized in Table [1](#T1){ref-type="table"}. ###### Principal diagnosis of readmission, initial admission-congestive heart failure (APR DRG 194), Syracuse hospitals, 2011-2012 Number of readmission Percent of total ----------------------------------------- --------------------------- ---------------------- ---- ---- ---- ----- ------- ------- Crouse Hospital 1Q 2011 3 1 4 1 0 9 33.33 66.67 1Q 2012 18 1 3 0 3 27 66.67 33.33 2Q 2011 7 1 3 2 0 13 53.85 46.15 2Q 2012 3 0 2 2 0 7 42.86 57.14 3Q2011 10 0 1 1 0 13 76.92 23.08 3Q 2012 6 3 1 0 1 14 42.86 57.14 4Q 2011 7 1 2 1 0 15 46.67 53.33 4Q 2012 4 0 2 2 2 10 40.00 60.00 Total 2011 27 3 10 5 0 50 54.00 46.00 Total 2012 31 4 8 4 6 58 53.45 46.55 St Joseph's Hospital Health Center IQ 2011 7 3 3 1 0 13 5385 46.15 1Q 2012
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23584, 3369, 10309, 15, 604, 368, 9829, 326, 23647, 13, 368, 476, 15, 1532, 187, 187, 4, 3944, 1358, 68, 1596, 267, 17, 939, 486, 15, 35946, 36642, 15, 681, 16, 6622, 16, 740, 16, 23593, 272, 14, 45047, 14, 11448, 14, 1171, 14 ]	After washing the wells, biotinylated anti-mouse IFN-γ antibody (2 μg/ml) was added and incubated for 2 h at room temperature. Then, a streptavidin-horseradish peroxidase solution was added and incubated for 1 h at room temperature. After the addition of an aminoethly carbazole substrate solution, spots were counted under a stereomicroscope. Tetramer staining and fluorescence-activated cell sorting analysis {#Sec13} ------------------------------------------------------------------ The CT26-specific H-2Ld MuLVgp70 (AH-1) peptide tetramer and H-2Ld p815 peptide tetramer were purchased from MBL Inc. (Nagoya, Japan), and fluorescein isothiocyanate (FITC)-anti mouse CD8 antibody were from BD Biosciences. For cell staining, the manufacturer's protocol was followed. Spleens were harvested from the mice, and after washing, the cells were incubated with tetramer and antibody in a total volume of 100 μl PBS with 2% FBS for 30 min at 4 °C and then fixed. Cells were analyzed by fluorescence-activated cell sorting (FACSCalibur; BD Bioscience). Irrelevant IgG was used as a negative control. Ten thousand live events were acquired for analysis. The ratio of tetramer^+^ cells was calculated as the frequency of AH-1^+^ or P815^+^ cells among CD8^+^ T cells. Immunohistochemistry and the assessment of transferred DTA-1 antibody into lymph nodes {#Sec14} -------------------------------------------------------------------------------------- Immunostaining was performed using the streptavidin-biotin-peroxidase complex techniques (Nichirei, Tokyo, Japan). Consecutive cryostat tissue sections (5 μm) were mounted on glass slides and fixed in 99.5% ethanol for 20 min. After blocking with normal rat serum, the sections were stained with rat anti-mouse CD4 and CD8 (BD Biosciences). Negative controls without primary antibodies were examined in all cases. The sections were counterstained with methylgreen. Immunohistochemical staining of tumor-draining lymph nodes (TDLNs) for Rat IgG (DTA-1) was performed using the streptavidin-biotin-peroxidase complex techniques (Nichirei). Immunohistochemical scoring criteria defined as the following, 3+: Circumferential membrane staining that is complete, intense, and within \>10% of lymph node cells. 2+: Circumferential membrane staining that is incomplete and/or weak/moderate and within \>10% of lymph node cells, or complete and circumferential membrane staining that is intense, and within ≦10% of lymph node cells. 1+: Incomplete membrane staining that is faint/barely perceptible and within \>10% of lymph node cells. 0: No staining is observed, or membrane staining that is incomplete and is faint/barely perceptible and within ≦10% of lymph node cells. The histologic scoring was evaluated by a pathologist (N. H.) in a blinded manner. Statistical analysis {#Sec15} -------------------- Comparative analyses of the data were performed by one-way ANOVA with Tukey's post-hoc test for multiple pairwise testing, and the Student's t-test when two groups were compared, using SPSS statistical software (SPSS Japan Inc., Tokyo, Japan). P \< 0.05 was considered as a significant difference. Supplementary information ========================= {#Sec16} Supplementary Dataset 1 Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Supplementary information ========================= Supplementary information accompanies this paper at 10.1038/s41598-019-41724-x. DTA-1 hybridoma, which produced anti-GITR agonistic antibody (DTA-1 Ab), was kindly provided from Prof. Shimon Sakaguchi, Immunology Frontier Research Center, Osaka University. This work was supported in part by a grant-in-aid for Practical Research for Innovative Cancer Control by Japan Agency for Medical Research and Development (15ak0101043 and 15ck0106166), by the National Cancer Center Research and Development Fund (26-A-11 and 26-A-12) and by YOKOYAMA Foundation for Clinical Pharmacology (YRY1513). K.N. designed and performed the experiments, analyzed data and wrote the manuscript; R.M., C.S., M.H., Y.M. and N.H. performed the experiments, and analyzed data; R.U. and H.H. supported the experiments; T.Y. designed the experiments and interpreted data; K.A. supervised the projects, interpreted data and wrote the manuscript. Competing Interests {#FPar1} =================== The authors declare no competing interests. The University of Houston (UH) is refusing to remove a student government executive from office after she angered many students with a tweet saying “All Lives Matter.” “SGA has always been ‘of the students, by the students and for the students’ and UH’s system of shared governance does not allow administrative intervention in SGA,” UH President Renu Khator states in an email sent to students and faculty Thursday. “Having said that, it is our responsibility to maintain a culture of inclusion in which all voices are heard and constructive discourse is not only protected, but also encouraged.” “UH remains committed to the principles of free and open expression.” The statement was made in response to demands from some students that Khator force Student Body Vice President Rohini Sethi out of office for posting “Forget #BlackLivesMatter; more like #AllLivesMatter” on Facebook hours after a black gunman shot and killed five police officers in Dallas, Texas last week. UH students and their supporters began a Twitter campaign, popularizing “#RemoveRohini” and eventually impelling her to apologize for the post. [RELATED: Saying ‘all lives matter’ lands student gov exec in hot water] Khator, however, is flatly rejecting that notion, saying in the email that her administration is committed to protecting free speech, and will not allow the pursuit of inclusivity to override the need to respect differences of opinion. “The University and I stand firm on the values of diversity, inclusion, and unity,” Khator wrote. “But differences of opinion are the natural byproduct of such discourse, and UH remains committed to the principles of free and open expression. “Ultimately, universities bring empowerment through education and understanding,” she continued, urging students “to engage in respectful discussion, behavior, and activities regarding this matter and all such issues.” Follow the author of this article on Twitter: @RiersonNCQ: Displaying on label I want to display some text means name of any source file with extension in a label. 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296, 7077, 64, 313, 29361, 18807, 13, 11356, 27, 25853, 2499, 5687, 13, 15750, 558, 285, 6277, 3972, 1216, 13, 795, 510, 10834, 273, 253, 1608, 14990, 64, 313, 4257, 2816, 27, 22663, 19346, 39265, 23538, 13, 7901, 481, 187, 187, 13617, 1668, 187, 187, 18, 15, 6911, 10718, 285, 13089, 14296, 13, 795, 510, 19988, 11292, 273, 253, 10363, 90, 2147, 44326, 26962, 64, 313, 40375, 2971, 13, 36989, 27, 4913, 5720, 5687, 13, 5307, 558, 7252, 5490, 13, 795, 510, 19988, 11292, 273, 41079, 26962, 64, 313, 4257, 2816, 27, 5602, 17993, 266, 13, 8210, 558, 285, 6911, 10188, 70, 13, 1407, 904, 795, 3546, 783, 14627, 285, 253, 15574, 273, 34959, 64, 313, 19346, 10765, 27, 6456, 327, 14559, 780, 32923, 1271, 13, 8210, 481, 187, 187, 13617, 1722, 187, 187, 18, 15, 733, 778, 320, 247, 3480, 273, 816, 841, 15711, 326, 762, 23677, 3332, 5012, 273, 10021, 9969, 275, 1966, 23792, 6771, 2561, 1128, 2887, 16543, 427, 504, 13692, 13, 346, 2422, 1851, 264, 3506, 5123, 8874, 293, 5034, 27828, 937, 795, 30466, 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300, 6711, 4805, 275, 253, 8530, 7088, 6794, 1263, 15, 380, 3236, 19213, 3929, 313, 26366, 350, 427, 15, 367, 18272, 413, 285, 7252, 329, 15, 35122, 13, 346, 3351, 35663, 273, 47803, 285, 25632, 2752, 11224, 1204, 937, 795, 24093, 273, 34959, 285, 4775, 64, 608, 313, 28355, 2262, 20105, 1253, 17391, 10, 2529, 47955, 8450, 3982, 327, 407, 3714, 300, 6711, 4805, 275, 17330, 6852, 5953, 4726, 3484, 15, 1723, 13, 359, 3735, 2717, 670, 253, 275, 2275, 363, 456, 7715, 5207, 2561, 2285, 2758, 40754, 949, 13790, 13, 32861, 1411, 247, 3369, 13, 285, 34131, 19944, 342, 271, 8829, 273, 46271, 3875, 12358, 2, 2594, 15940, 35218, 3642, 13, 346, 510, 7088, 6794, 28111, 27, 329, 19388, 14, 25438, 10519, 19166, 14, 5683, 285, 8378, 1975, 22956, 2271, 937, 795, 24093, 273, 4480, 21941, 29624, 64, 3495, 313, 14209, 2262, 337, 1253, 1619, 15, 187, 187, 22, 15, 2594, 990, 9939, 1852, 18, 13, 8857, 1903, 15, 187, 187, 13617, 655, 187, 187, 18, 15, 380, 6178, 273, 3714, 300, 6711, 4805, 326, 19962, 285, 5685, 2561, 2390, 3839, 897, 13, 470, 15, 19, 5770, 16, 5840, 13, 310, 1679, 685, 581, 14, 14674, 253, 6178, 359, 1119, 651, 3324, 327, 271, 49273, 494, 32884, 2147, 44326, 2380, 28, 326, 310, 13, 470, 15, 1857, 5770, 16, 5840, 15, 3900, 841, 2390, 452, 3863, 616, 941, 347, 7809, 346, 19060, 2147, 44326, 2538, 273, 3714, 300, 6711, 4805, 937, 309, 1053, 626, 1158, 752, 597, 403, 12392, 310, 247, 6867, 9237, 15, 2594, 444, 15, 443, 276, 91, 3941, 261, 14, 6791, 925, 1164, 13, 378, 15, 380, 5025, 13, 444, 15, 25181, 693, 21776, 13, 388, 15, 500, 15, 31292, 797, 13, 611, 8634, 34, 15, 611, 729, 274, 13, 388, 15, 12529, 257, 1559, 1595, 13, 418, 15, 19423, 282, 13, 353, 15, 2101, 13412, 13, 285, 388, 15, 322, 515, 13, 346, 36831, 28342, 13, 22054, 423, 21959, 285, 5271, 22255, 24350, 273, 495, 13, 21, 14, 46, 4040, 2348, 900, 5246, 4040, 35877, 313, 46, 2573, 582, 10363, 300, 6711, 4805, 285, 277, 14, 46, 678, 35877, 275, 39219, 39067, 398, 937, 795, 36831, 2689, 42244, 1497, 64, 21669, 313, 9595, 2262, 7609, 1253, 1235, 28, 285, 401, 15, 1594, 15, 657, 25733, 664, 1334, 13, 611, 15, 418, 15, 2070, 13577, 13, 330, 15, 322, 3615, 39792, 350, 13, 367, 15, 6813, 86, 603, 13, 473, 15, 659, 11391, 8420, 13, 285, 500, 15, 4965, 296, 13, 346, 13839, 262, 1406, 444, 2230, 6270, 3756, 285, 43082, 853, 9356, 40119, 11709, 273, 6365, 20038, 25411, 6342, 1319, 285, 13219, 36691, 275, 253, 10363, 300, 6711, 4805, 10031, 273, 13219, 2433, 937, 795, 6560, 1822, 20980, 2689, 42244, 1497, 64, 1668, 313, 12430, 2262, 34506, 1253, 3547, 15, 187, 187, 31, 844, 4821, 20092, 839, 253, 6178, 598, 1919, 337, 15, 18, 5770, 16, 5840, 13, 387, 534, 1127, 253, 767, 15986, 6883, 326, 10671, 3543, 352, 369, 346, 15627, 1199, 449, 2596, 3395, 13366, 557, 21085, 13, 285, 253, 643, 7407, 247, 3282, 273, 4829, 16400, 346, 30132, 3473, 449, 844, 497, 1469, 281, 897, 470, 15, 26, 5770, 16, 5840, 347, 776, 1029, 14, 423, 6178, 273, 3714, 300, 6711, 4805, 13, 625, 685, 1740, 2069, 253, 5284, 346, 19060, 2147, 44326, 6178, 937, 1078, 3081, 5989, 3977, 281, 619, 6108, 253, 9835, 15, 187, 187, 13617, 1384, 187, 187, 18, 15, 15940, 500, 15, 7962, 515, 1342, 285, 22662, 7667, 266, 350, 13, 346, 510, 3506, 73, 301, 41735, 27, 329, 10547, 14, 36, 10222, 11683, 273, 3050, 3535, 937, 795, 22817, 9109, 8404, 13219, 5946, 610, 64, 3436, 313, 16134, 2262, 34360, 1253, 2270, 15, 187, 187, 19, 15, 831, 1332, 310, 3240, 2074, 281, 752, 30435, 1925, 346, 9154, 314, 14116, 4116, 3, 2684, 407, 247, 10166, 30543, 29965, 296, 15, 380, 23960, 3400, 1329, 949, 6571, 11561, 533, 1246, 7063, 3212, 285, 745, 281, 253, 1930, 273, 253, 3110, 434, 21985, 15, 831, 1511, 273, 440, 706, 1206, 15240, 11298, 285, 7487, 27034, 1199, 273, 752, 3936, 1659, 26506, 1309, 26167, 23986, 15, 187, 187, 20, 15, 1198, 1650, 13, 627, 403, 1024, 9883, 13, 9890, 13, 7247, 13, 26467, 13, 5685, 13, 285, 13986, 29971, 273, 253, 388, 6453, 15, 25838, 2561, 2390, 1475, 253, 1533, 452, 908, 352, 281, 2557, 253, 2538, 273, 23792, 6771, 13, 795, 333, 20957, 4843, 66, 64, 1157, 32263, 6168, 35753, 13, 3714, 300, 6711, 4805, 13, 285, 10399, 3788, 15, 329, 5685, 2561, 1387, 556, 1014, 4080, 2176, 3386, 273, 10748, 12952, 49697, 342, 253, 388, 6453, 15, 187, 187, 21, 15 ]	1. This idea is a common one in people who use psychedelics for personal growth. It has to do with the purifying and relieving value of catharsis. A powerful, earth-shattering emotional experience might prove more useful than lengthy verbal analysis of the same conflict. In clinical practice, however, both methods of dealing with blocked emotional growth are necessary. Catharsis without any insight may not have much long-term benefit. But insight without emotional contact usually leads to little real progress. Chapter 12 1. Chaco Canyon is a spectacular ruins site about three hours northwest of Albuquerque. The Anasazi Indians, probable precursors of the contemporary Pueblo tribes, inhabited it for centuries. From where the Anasazi came from, and to where they went upon abandoning this stone city in the mid-thirteenth century, remain two of the world's greatest archeological mysteries. Their astronomical skills were extraordinarily sophisticated, and they supported themselves using irrigation and agricultural techniques that stagger the mind, considering the minimal rainfall with which they had to contend. Chaco Canyon weaves a compelling spell upon any who visit it, and many people make the pilgrimage with an almost mystical fervor. 2. Runes are an ancient Nordic divination tool, similar to the I Ching and the Tarot. Runes date from at least 1000 B.C. and use stones with symbols carved on them, rather than sticks or cards. Modern runes use twenty-five different symbols. 3. "Regular" in Spanish means "regular," "normal," "everyday." The proper pronunciation accents the last syllable. 4. In classical Greek and neo-Platonic philosophy, the Logos is the cosmic reason giving order, purpose, and intelligence to the world. 5. Carlos Castaneda performed anthropology fieldwork in the Mexican desert, spending years with an Indian shaman, Don Juan Matus. Many of the scenes Castaneda describes begin as simple encounters with Don Juan and his friends, in settings similar to that which Sean described. See, for example, Carlos Castaneda, _The Teachings of Don Juan: A Yaqui Way of Knowledge_ (Berkeley, CA: University of California, 1998). Chapter 13 1. Z. Boszormenyi and Stephen I. Szára, "Dimethyltryptamine Experiments with Psychotics," _Journal of Mental Science_ 104 (1958): 445–53. 2. Turner and Merlis (1959). 3. Gumby is a character from an American children's television show from the late 1950s and early 1960s. Gumby was composed of a claylike substance molded over metal wire. This made it possible to bend him into all sorts of shapes, something kids loved doing with their own twelve-inch-tall Gumby. Gumby's trusty sidekick was Pokey the horse. The animators bent and moved Gumby's and Pokey's clay bodies, then filmed them using time-lapse photography, thus giving the impression of movement. Chapter 14 1. John E. Mack, Abduction (New York: Ballantine, 1994) and _Passport to the Cosmos_ (New York: Crown, 1999). Chapter 15 1. Raymond A. Moody, _Life After Life_ (New York: Bantam Books, 1988); and Kenneth Ring, _Life at Death: A Scientific Investigation of the Near-Death Experience_ (New York: Coward, McCann, and Geoghegan, 1980). 2. W. Y. Evans-Wentz, _Tibetan Book of the Dead_ (New York: Oxford University Press, 1974). 3. Rinpoche Sogyal, _The Tibetan Book of Living and Dying_ (New York: HarperSanFrancisco, 1992). This is a modern rendition of _The Tibetan Book of the Dead._ 4. Dannion Brinkley, _Saved by the Light_ (New York: Harper, 1995); and Betty J. Eade, _Embraced by the Light_ (New York: Bantam, 1994). 5. Mircea Eliade, _Shamanism: Archaic Techniques of Ecstasy_ (Princeton, NJ: Princeton University Press, 1972); and Michael Harner, _The Way of the Shaman_ (New York: HarperSanFrancisco, 1990). Chapter 16 1. Robert Master and Jean Houston, _The Varieties of the Psychedelic Experience_ (Rochester, VT: Park Street Press, 2000); William James, _The Varieties of Religious Experience_ (New York: Macmillan, 1997); and Robert Forte, ed., _Entheogens and the Future of Religion_ (San Francisco: Council on Spiritual Practices, 1997). Chapter 17 1. It may be a lack of just these considerations that underlies recent reports of adverse reactions in human ketamine research—see Anna Nidecker, "Alleged Abuses Accelerate Reform," _Clinical Psychiatry News_ 26 (1998): 1. That is, did the scientists know what they were doing? Had they taken ketamine themselves? How carefully did they control the setting in which their subjects received ketamine? What were their attitudes and responses toward the ketamine-induced state? Of course, it is just these variables that one must think about in reading reports of adverse effects from the first wave of human psychedelic drug research in the 1950s and 1960s. 2. F. Kajtor and Stephen Szára, "Electroencephalographic Changes Induced by Dimethyltryptamine in Normal Adults," _Confinia Neurologica_ 19 (1959): 52–61. 3. Sai-Halasz et al. (1958). 4. More recently, Doblin brought to light a highly stressful negative reaction to psilocybin in the famous Good Friday study. The original 1966 article (Walter N. Pahnke and William A. Richards, "Implications of LSD and Experimental Mysticism," _Journal of Religion and Health_ 5 (1966): 175–208) described mystical experiences brought on by psilocybin in Harvard Divinity School students. However, we heard nothing about the inebriated fellow whom research team members chased through campus, pinned against a door, and tranquilized with an injection of antipsychotic medication! See Rick Doblin, "The Good Friday Experiment: A Twenty-Five Year Follow-Up and Methodological Critique," _Journal of Transpersonal Psychology_ 23 (1991): 1–28. 5. See endnote #1, chapter 11. Chapter 19 1. The dose of psilocybin that Swiss and German research groups generally use, 0.2 mg/kg, is less than one-half the dose we found would bring on an unmistakable psychedelic response; that is, 0.45 mg/kg. While these groups have published their data as indicating "psychedelic effects of psilocybin," I don't think what they are studying is a typical syndrome. See E. Gouzoulis-Mayfrank, B. Thelen, E. Habermeyer, H. J. Kunert, K.-A. Kovar, H. Lindenblatt, L. Hermle, M. Spitzer, and H. Sass, "Psychopathological, Neuroendocrine and Autonomic Effects of 3,4-Methylenedioxyethylamphetamine (MDE), Psilocybin and d-Methamphetamine in Healthy Volunteers," _Psychopharmacology_ 142 (1999): 41–50; and F. X. Vollenweider, K. L. Leenders, C. Scharfetter, P. Maguire, O. Stadelmann, and J. Angst, "Positron Emission Tomography and Fluorodeoxyglucose Studies of Metabolic Hyperfrontality and Psychopathology in the Psilocybin Model of Psychosis," _Neuropsychopharmacology_ 16 (1997): 357–72. > We continued escalating the dose up until 1.1 mg/kg, at which point the two volunteers receiving that quantity felt it was "too much." One became briefly disoriented, and the other experienced a sense of nearly overwhelming "mental pressure." We were going to use 0.9 mg/kg as our high-end dose of psilocybin, more than four times the European "psychedelic dose," before additional circumstances led to my leaving the university. Chapter 20 1. Rick J. Strassman and Marc Galanter, "The Abhidharma: A Cross-Cultural Application of Meditation," _International Journal Social Psychiatry_ 26 (1980): 283–90. 2. This method is quite similar to what Freud called "evenly suspended attention" performed by a trained psychoanalyst. The analyst provides support through mostly silent but present sitting behind and off to the side of the patient's couch. This type of unobtrusive listening and watching mirrors much of what takes place internally during Zen meditation. 3. For example, there are now Spanish, Italian, Russian, Portuguese, German, and Dutch translations of the HRS. Various research groups around the world have used it to measure the effects of ketamine, _ayahuasca_ , amphetamines, psilocybin, and MDMA. A German research group has even measured certain features of naturally occurring psychosis with the HRS. 4.
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449, 187, 187, 38657, 265, 16458, 497, 3365, 4886, 23584, 84, 15, 1707, 369, 2717, 281, 320 ]	muscles. And though the couch wasn't particularly soft — it felt like solid rock — I was almost submerged in it. But that was unimportant. What mattered was this — somehow the lifeship had to escape from Earth's gravity, and sometime it had to land on Mars. There wasn't enough fuel to do it. I could see that now, only a matter of seconds from takeoff. Ten people, lower down in the lifeship, were depending on me and on the ship for life that the ship and I weren't going to be able to give them. I was thinking like a prairie fire, though I was practically certain there was no solution. Soon I had a little piece of an answer. My fingers moved and the blast mounted. Anyone below who had thought nothing could be worse than 6G found his mistake as the acceleration went up and up. The ship was designed for four minutes' blasting, but if I were to save fuel there was only one way to do it. That was to get off more quickly, reach escape velocity, and stop blasting sooner, saving the fuel which would have been needed to hold the ship up during the extra time. I refused to think about the jet linings. They were designed for four minutes' blast, presumably, and now they were being asked to take the same thrust in less time. I nearly blacked out. I screamed and hardly heard myself. You won't understand how I felt physically unless the same kind of thing has happened to you — when you must and do remain conscious but you're so near unconsciousness that perceptions sent along the nerve channels to your brain simply don't leave any record there. You have to notice them as they happen or you've lost them forever. I strained my eyes at the dials in front of me, trying to make them mean that I could cut the drive. They persisted in telling the truth, which was no good to me. I saw why people sometimes strain to believe something they know is false. There are times when hopeful fantasy is much more attractive than hopeless fact. At last I was able to cut the drive. It had been on for hours. The chronometer said it was only three minutes or so, but I knew better. It didn't stop cleanly, as it should, it eased off gently. The couch gradually rose, and I floated off, weightless. You never quite get used to free fall, no matter how often you experience it. It's a surprise every time when up and down disappear from the environment and the normal way of getting about ceases to be beetlelike and becomes birdlike. It's amusing or frustrating, depending on how you're feeling at the time, when you want to go one way and find yourself going the other, impelled by some tiny movement of air you can't see and normally wouldn't notice at all. The body adjusts to the new conditions more quickly than the mind. The lungs and heart and stomach, puzzled for a few minutes by the absence of gravity, soon learn their new job and do it as well as they did the old one. Clothes and hair are inconveniences, though. Practically every garment of civilization except riding breeches and bathing costumes depends to some extent on gravity to hold it in place. Whenever I moved, my jacket began to ride up about me like water wings, and my trousers gradually worked themselves in untidy folds up my legs, showing the imprex tape underneath. I found Mars through the tungsten glass ports and began to check on the old space navigators' Irishism — whether it would be where we were when we got there. But I wasn't allowed much grace. Sammy Hoggan came in, his face grim. "Mary Stowe's dead," he said briefly. I couldn't understand that at first. Somebody dead — already? It interfered with my long-term calculation that we were all going to die. It jammed the works for a moment, this curious, irrelevant intimation that someone hadn't waited for the execution that appeared to be planned for us all. "Acceleration?" I asked. "That and her couch collapsing. It couldn't take the strain. Bill — didn't you accelerate more than you were supposed to?" "Yes," I said. "Then that killed her," he said bluntly. "The extra weight came on — and the couch broke. That was — " I had heard enough about Mary, and it was too late to do anything about her. "Go away," I said. Sammy swore. "Dammit, Bill," he said hotly, "you're responsible for all of us. You're the man in charge. Is that all you have to say? If you had to do it — " I turned and looked coldly at him. "I'm responsible for getting this ship to Mars," I said curtly. "I'm not leaving here until I'm satisfied about that — not if the whole lot of you die. If this room had a door, I'd lock it to keep you all out. Now go and leave me alone. I'm sorry, Sammy, but I haven't time to be civil." I went back to my calculations. I didn't notice Sammy going. The first check was encouraging, as far as it went. There could be no precision about flying a lifeship — navigation with mass-produced instruments, and very few of them at that, was little more than an affair of pointing the ship's nose in roughly the right direction and praying. And on this basis, it looked as if I could leave the course as it was and not waste any of my precious moluone making corrections. I wasn't too sure of our velocity — that would take days of checking by the planets — but it seemed that in about a hundred days the lifeship, in free fall, and Mars, in its orbit round the sun, would have reached about the same spot. Then, more carefully, I worked out how much fuel I'd need for a safe landing on Mars, how much I had, and tried to close the gap. Mathematically it couldn't be done. I just couldn't land safely on Mars, according to my quadruple-checked figures. I covered sheet after sheet with laborious calculation. The best I could produce, the most favorable extrapolation, crooked, weighted mathematics though it was, was still a very slim chance indeed. Drugged with figures, working more and more from sheer obstinacy, stubbornly trying everything I could think of to try, I came up with the conclusion that our chances of getting to Mars, when we left the soil of Earth, had been about a thousand to one against. And they weren't very much better now. True, we were clear of Earth and on a good course for Mars. We _were_ over the first hurdle. We had accomplished what, at a guess, only two or three hundred thousand of the seven hundred thousand lifeships had been able to do. And of those two or three hundred thousand, many must have used all their fuel in tearing themselves free of Earth. Those ships were utterly helpless. Some of them would be shooting off in all directions, every moment getting farther from Mars, and utterly incapable of doing anything about it. Some of them would be pointed at the sun, or close enough to the sun to be captured by it. Some would move on and on past the planets into space... those ships would go on forever if they weren't captured by some star or planet. I didn't swear or curse at anyone. I just doggedly worked out problem after problem, as if I could set everything right by my high school mathematics. On the basis of our own experience I worked out how much fuel the lifeships really needed. Then, since they would have to be so much bigger and stronger, how many lifeships there would have been instead of seven hundred thousand. How many people they could have taken. Allowing a very small safety factor, it came out at ninety-seven thousand. A chance of life for a million people instead of nearly eight million. Not one in three hundred of the people of Earth, but one in twenty-two hundred. I tried to imagine the job I might have had then, the job of picking out ten people from a town of over twenty thousand. As it was, I knew hardly anything about some of the people I'd chosen from a mere three thousand or so. Sammy, Leslie, Betty, and Morgan were all last-minute choices, because someone else had had to come off the list. On the whole I was prepared to gamble on the first two, but Morgan and Betty could be my best choice or my worst for all I knew. What sort of guess could I have made if I'd been confronted with twenty thousand people and told to pick ten? I shook my head wearily. The questions were too big for me. I had juggled too long with figures of life and death — a little life and a lot of death. They weren't anything but figures to me. Perhaps that was why I had done it — to reduce humanity's most frightful disaster to a few real figures, like four and seven and three, with a lot of incomprehensible zeroes after them. I would come again, no doubt. But meantime I had reached a mental dead stop. # _2_ I gave myself a push against the wall, guided myself with my arms, and swam out into the main room of the lifeship, which Sammy had already christened, ironically, "the lounge." Lifeships were simply moving barns. There was nothing to be
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href="PyML.containers.ext.ckernel.FloatVector-class.html#insert">insert()</a><br /> <span class="index-where">(in <a href="PyML.containers.ext.ckernel.FloatVector-class.html">FloatVector</a>)</span></td> <td width="33%" class="link-index"><a href="PyML.classifiers.ext.csvmodel-module.html#IntVector_swigregister">IntVector_swigregister</a><br /> <span class="index-where">(in <a href="PyML.classifiers.ext.csvmodel-module.html">PyML.classifiers.ext.csvmodel</a>)</span></td> <td width="33%" class="link-index"><a href="PyML.containers.ext.csparsedataset.IntVector-class.html#iterator">iterator()</a><br /> <span class="index-where">(in <a href="PyML.containers.ext.csparsedataset.IntVector-class.html">IntVector</a>)</span></td> </tr> <tr> <td width="33%" class="link-index"><a href="PyML.containers.ext.ckernel.IntVector-class.html#insert">insert()</a><br /> <span class="index-where">(in <a href="PyML.containers.ext.ckernel.IntVector-class.html">IntVector</a>)</span></td> <td width="33%" 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1807, 262, 484, 15, 681, 23006, 634, 11068, 15, 187, 187, 6693, 3367, 1491, 368, 2085, 281, 441, 1690, 285, 2074, 281, 634, 1416, 13, 2953, 13, 11265, 1180, 285, 299, 14, 5719, 2953, 588, 417, 320, 4439, 13, 4211, 13, 390, 33437, 281, 667, 14429, 390, 4292, 3345, 273, 714, 1807, 262, 484, 15, 681, 15, 187, 187 ]	of all, why is reality itself going haywire in the vicinity of Cliff’s office? To learn the answers to these questions, Cliff will have to sacrifice everything — and everybody — that has ever been precious to him. And even then, there’s no guarantee that he’ll like what he discovers. Especially when it points toward the overthrow of the ultimate Creator of the universe itself... First published in samizdat form in 1985, this rollicking, inventive, and blasphemous sci-fi adventure heralded the emergence of Perry Slaughter as a force to be reckoned with in American letters. Nearly three decades later, Deus ex Machina still retains its power to shock, astound, and entertain. by Sinister Regard £1.27 With the computer called ARTHUR, Cliff Peabody has made a major breakthrough in artificial intelligence. It should be the most triumphant event of his professional career — but why, then, is the federal government invading his laboratories? Why is half the country suffering an inexplicable power outage? And, most disturbing of all, why is reality itself going haywire in the vicinity of Cliff’s office? To learn the answers to these questions, Cliff will have to sacrifice everything — and everybody — that has ever been precious to him. And even then, there’s no guarantee that he’ll like what he discovers. Especially when it points toward the overthrow of the ultimate Creator of the universe itself... First published in samizdat form in 1985, this rollicking, inventive, and blasphemous sci-fi adventure heralded the emergence of Perry Slaughter as a force to be reckoned with in American letters. Nearly three decades later, Deus ex Machina still retains its power to shock, astound, and entertain. by Sinister Regard It is January 1, 1913; and Ilaytha is about to begin her service as a test subject to the warlock Edwin Hubble. Despite being a brilliant scientist, Ilaytha is human and thus will never be able to work on her own. Only warlocks like Sergei Diaghilev and Henri Becquerel are allowed to pursue art, science, or literature. Humans exist to perform hard labor and to produce warlock children; but Ilaytha believes herself to be the exception to the rule. Her pride will force her to learn what lies behind the façade the warlocks have created. £0.99 It is January 1, 1913; and Ilaytha is about to begin her service as a test subject to the warlock Edwin Hubble. Despite being a brilliant scientist, Ilaytha is human and thus will never be able to work on her own. Only warlocks like Sergei Diaghilev and Henri Becquerel are allowed to pursue art, science, or literature. Humans exist to perform hard labor and to produce warlock children; but Ilaytha believes herself to be the exception to the rule. Her pride will force her to learn what lies behind the façade the warlocks have created. When psychotherapist Claire Walsch is contracted – against her will – to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that her life is about to be turned upside down. What Claire really wants is to ask some questions, sign some papers and walk away. What she gets is a dangerous adventure with a woman who is uncomfortably unpredictable. An adventure which brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum £5.64 When psychotherapist Claire Walsch is contracted – against her will – to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that her life is about to be turned upside down. What Claire really wants is to ask some questions, sign some papers and walk away. What she gets is a dangerous adventure with a woman who is uncomfortably unpredictable. An adventure which brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum Appleseed - Ex-Machina [Blu-ray]. Import from The Netherlands. Language: English, French Subtitles: English, French, Dutch Producer John Woo's updating of the Japanese anime series. In the year 2133, the Third World War has devastated mankind, and has led to the creation of a utopian society in the hi-tech city of Olympus. Deunen is a female warrior from the scorched wastlelands who meets her long lost boyfriend, Briareos, who has been transformed into a half-machine cyborg. The pair's partnership is tested when Jude Tereus, a 'battle bioroid' joins their ESWAT team. Even more worrying is the fact that Tereus was constructed using Briareos's DNA, causing him to have feelings for Deunen. As Olympus gets ready to hold a global trade summit, the city is hit by a wave of terrorist cyborg attacks. With an increasing number of cyborgs rebelling, Deunen finds herself having to partner Tereus as the terrorist campaign intensifies. £5.98 was £6.98 Price dropped on 9th Jan 2018 Appleseed - Ex-Machina [Blu-ray]. Import from The Netherlands. Language: English, French Subtitles: English, French, Dutch Producer John Woo's updating of the Japanese anime series. In the year 2133, the Third World War has devastated mankind, and has led to the creation of a utopian society in the hi-tech city of Olympus. Deunen is a female warrior from the scorched wastlelands who meets her long lost boyfriend, Briareos, who has been transformed into a half-machine cyborg. The pair's partnership is tested when Jude Tereus, a 'battle bioroid' joins their ESWAT team. Even more worrying is the fact that Tereus was constructed using Briareos's DNA, causing him to have feelings for Deunen. As Olympus gets ready to hold a global trade summit, the city is hit by a wave of terrorist cyborg attacks. With an increasing number of cyborgs rebelling, Deunen finds herself having to partner Tereus as the terrorist campaign intensifies. When psychotherapist Claire Walsch is contracted - against her will - to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that she is about to experience something far beyond her belief. The physical, mental and psychological journey that follows brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. ..".I couldn't put this book down. It was fast paced, action packed with strong female characters. Awesome read!" "Talk about keeping you on the edge of your seat! This was really good right from the get go... Get this book I highly recommend it and I hope there is a sequel coming in the future." "adjective: excellent 1. extremely good; outstanding..." Reader Reviews, Amazon.com "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum by Createspace £8.99 When psychotherapist Claire Walsch is contracted - against her will - to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that she is about to experience something far beyond her belief. The physical, mental and psychological journey that follows brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. ..".I couldn't put this book down. It was fast paced, action packed with strong female characters. Awesome read!" "Talk about keeping you on the edge of your seat! This was really good right from the get go... Get this book I highly recommend it and I hope there is a sequel coming in the future." "adjective: excellent 1. extremely good; outstanding..." Reader Reviews, Amazon.com "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum by CreatespaceFunny Jokes, Quotes, Videos & More Privacy Policy Yuckitup.com respects your privacy. Any personal information you provide to us including and similar to your name, address, telephone number and e-mail address will not be released, sold, or rented to any entities or individuals outside of Yuckitup.com.
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387, 33269, 1340, 15, 496, 1091, 13, 12604, 91, 2284, 556, 6808, 247, 3908, 347, 3637, 27, 187, 187, 31840, 327, 6926, 13, 275, 247, 4014, 13337 ]	PM COPY THAT! 10-4, we're outa here............ WAIT! I just read this article: http://www2.ljworld.com/news/2012/feb/25/us-taliban-talks-worry-afghan-women/ meh... now, I dunno.:concern:.......should we give it up? Yes, unless of course we plan on spending the next century there. We have enough problems, we don't need theirs. Teetop 02-25-2012, 03:51 PM I wish someone would've wiped their ass with the pages just to see the frenzy that would've ensued. :biggrin: You asked, here it is. (http://moonbattery.com/?p=8533) Odysseus 02-25-2012, 04:21 PM You asked, here it is. (http://moonbattery.com/?p=8533) http://www.youtube.com/watch?v=69VIER7nzz8&feature=player_embedded#! A few other highlights of the hypocrisy of the Muslims on this subject: From the description of the Wahhabi takeover of the town of Taif, in Saudi Arabia: The Wahabbis tore up the copies of the Qur’an al-karim and books of Tafsir, Hadith and other Islamic books they took from libraries, Musjids and houses and threw them down on the ground. They made sandals from the gold-gilded leather covers of the Qur’an copies and other books and wore them on their filthy feet. There were ayats and other sacred writings on those leather covers. Leaves of those valuable books thrown around were so much that there was no space to step in the streets of Taif. Although Ibn Shakban had ordered the looters not to tear up the copies of the Qur’an al-karim, the Wahabite bandits , who were gathered from the deserts for looting and who did not know the Qur’an al-karim, tore up all the copies they found and stamped on them. Only three copies of the Qur’an al-karim and one copy of the Sahih of al-Bukhari were saved form plunder in the big town of Taif. Malawi Muslims burn Gideons Bibles in protest October 5, 2010 @ 6:25 pm By Reuters Staff http://blogs.reuters.com/faithworld/files/2010/10/bible-350x252-custom.JPGMuslims in southern Malawi have been burning Bibles in protest against their distribution in Islamic schools byGideons International (http://www.gideons.org/Splash.aspx) [1], a senior Muslim Association of Malawi official said on Tuesday. Sheikh Imran Sharif, the association’s secretary general, said the burning of Bibles was carried out by a few Muslim fanatics and the association has ordered them to stop. The Muslim protest has been widely criticised in secular Malawi, which has had little religious friction. (Photo: Bible, 14 Dec 2008/Edgeurged)Malawi has 1.7 million Muslims, mostly living in the south of the country, that has a population of about 15 million. Gideons International, which is dedicated to providing copies of the Bible to people around the globe, said on its website it has distributed about 90 million Bibles in 22 countries in eastern Africa. http://www.youtube.com/watch?v=4pPz4xfcvu8 Military burns unsolicited Bibles sent to Afghanistan Story Highlights Unsolicited Bibles sent by U.S. church were confiscated about a year ago The Bibles were printed in two most common Afghan languages Military feared they could be used for proselytizing, which is forbidden to troops Military didn't want to risk any distribution of the Bibles and angering Muslims d/div>v!--startclickprintexclude-->(CNN) -- Military personnel threw away, and ultimately burned, confiscated Bibles that were printed in the two most common Afghan languages amid concern they would be used to try to convert Afghans, a Defense Department spokesman said Tuesday. The unsolicited Bibles sent by a church in the United States were confiscated about a year ago at Bagram Air Base in Afghanistan because military rules forbid troops of any religion from proselytizing while deployed there, Lt. Col. Mark Wright said. Such religious outreach can endanger American troops and civilians in the devoutly Muslim nation, Wright said. "The decision was made that it was a 'force protection' measure to throw them away, because, if they did get out, it could be perceived by Afghans that the U.S. government or the U.S. military was trying to convert Muslims," Wright told CNN on Tuesday. Troops at posts in war zones are required to burn their trash, Wright said. The Bibles were written in the languages Pashto and Dari. This decision came to light recently, after the Al Jazeera English network aired video of a group prayer service and chapel sermon that a reporter said suggested U.S. troops were being encouraged to spread Christianity. The military denied that earlier this month, saying much in the video was taken out of context. "This was irresponsible and dangerous journalism sensationalizing year-old footage of a religious service for U.S. soldiers on a U.S. base and inferring that troops are evangelizing to Afghans," Col. Gregory Julian said. The military says a soldier at Bagram received the Bibles and didn't realize he wasn't allowed to hand them out. In the Al Jazeera video, which shows the Bibles at the prayer service, an unnamed soldier says members of his church raised money for them. The chaplain later corrected the soldier and confiscated the Bibles, Wright said. RedGrouse 02-25-2012, 07:55 PM Assuming this even happened. All it takes is one local insurgent to start the RUMOR that a Koran is being burned to whip the uneducated masses into a frenzy over there. Like in Uruzgan Province last year when the Taliban tried to claim we bayonetted a Koran. That got the locals riled up until we pointed out to the provincial elders the 30 year old soviet bayonet stuck in the Koran wasn't used by either Australian or American forces. This is the Taliban propaganda wing yanking ISAFs chain and getting a 4 Star General to jump for them. And yes I know they reportedly found pieces of a Koran. We found pre burnt Korans in raids last year. Paranoia runs deep in them and I mean really deep. Kay 02-26-2012, 12:42 AM I can't even read on this subject without needing an extra blood pressure pill. Where were all the riots over the Taliban blowing up the hillside Buddhas? Oh yeah, Buddists, Christians and other Godly religions don't do this sort of thing. Only pure evil cults do. We won the wars both in Iraq and the shithole of Afghan, but we lost the wars for the hearts and minds. We've done all the good we are ever going to do there. We have given them an infrastructure, trained their police and military and shown them what a better way of life can be like. Now it's up to them. They can sink or swim. We need to just get all our people out of there I say. Kay 02-26-2012, 01:05 AM But my 1st preference would have been this: The third option is the punitive expedition. Simply put, we could have hit the Afghans hard, destroyed as much of the country as possible in as short a time as possible, and warned them that if they messed with us again, we'd be back in force to finish the job. We'd have left the countryside in ruins and created a humanitarian disaster, but we'd also have let the world know that were were not to be trifled with. The example of this paradigm occurs throughout history, from the Greek's destruction of Troy, Alexander's destruction of Thebes, Rome's destruction of Carthage, Jerusalem and the various tribal strongholds of northern Europe, and various other atrocities. Of course, the survivors would hate us, but they would also fear us, and, as Machiavelli famously wrote, it is better to be feared than loved. Also, given the nature of our enemies, they'd have understood and expected this response, as it is what they would have done if the roles were reversed. The rest of the world would have screamed bloody murder, but let's face it, they were going to do that no matter what we did. Starbuck 02-26-2012, 12:24 PM Obama made a serious mistake in apologizing for the burning of the Koran. He should have stood his ground defiantly or, lacking that spine, should have said nothing. Now we are told that he has sent Hamid Karzai a letter of apology and thanked Karzai for his efforts at restoring order. In return, Karzai has issued a statement as follows: Earlier on Sunday, in a televised
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965, 1163, 309, 452, 25753, 625, 289, 386, 2233, 2069, 285, 352, 434, 1335, 2444, 2195, 733, 310, 417, 5553, 14, 16894, 3346, 187, 187, 42, 816, 3524, 1046, 2133, 434, 3735, 15, 380, 25080, 310, 253, 12967, 2, 831, 310, 247, 2969, 2813, 281, 1132, 6201, 9750, 25080, 1663, 31311, 672, 3095, 19055, 745, 253, 3200, 8468, 15, 1310, 368, 1053 ]	cause” of ISIS except only in the sense that the “failure” to exact regime change in Syria has prompted the West to continue propping up ISIS and other terrorist groups until the government in Damascus falls – and only when Damascus’ regional and global allies abandon it. The West Got What it Wanted in Libya – And Created ISIS in the Process The West’s claims during the Vienna talks that if only they get their way in Syria, the threat of ISIS will subside, is betrayed by the events surrounding the very rise of ISIS in Syria in the first place. Just before the conflict reached critical mass in Syria during 2011, the US, UK, France, other NATO members, as well as Saudi Arabia, Qatar, and the United Arab Emirates (UAE), were already in the process of fully dividing and destroying Libya in pursuit of regime change. They insisted that regime change was the only way to end the bitter fighting that had swept the country – regime change that just so happened to fulfill the long-held desire by Washington and Europe to see Libyan leader Muammar Qaddafi ousted from power. Through arming what the West called “rebels,” and through direct military intervention which included large-scale, nationwide airstrikes, naval bombardments, and even special forces, NATO devastated the country and turned it over literally to Al Qaeda. The West’s “rebels” turned out to be sectarian extremists all along, and in fact – with NATO’s help – they promptly took their weapons, fighters, and cash to begin the invasion of northern Syria via Turkey later that year. The Business Insider would report in its article, “REPORT: The US Is Openly Sending Heavy Weapons From Libya To Syrian Rebels,” that: The administration has said that the previously hidden CIA operation in Benghazi involved finding, repurchasing and destroying heavy weaponry looted from Libyan government arsenals, but in October we reported evidence indicating that U.S. agents — particularly murdered ambassador Chris Stevens — were at least aware of heavy weapons moving from Libya to jihadist Syrian rebels. There have been several possible SA-7 spottings in Syria dating as far back as early summer 2012, and there are indications that at least some of Gaddafi’s 20,000 portable heat-seeking missiles were shipped before now. On Sept. 6 a Libyan ship carrying 400 tons of weapons for Syrian rebels docked in southern Turkey. The ship’s captain was “a Libyan from Benghazi” who worked for the new Libyan government. The man who organized that shipment, Tripoli Military Council head Abdelhakim Belhadj, worked directly with Stevens during the Libyan revolution. Belhadj, it should be mentioned, was the commander of US State Department-listed foreign terrorist organization, the Libyan Islamic Fighting Group (LIFG) – which is literally Al Qaeda in Libya – and was so before, during, and after the 2011 Libyan war. Belhadj was also reportedly aligned with ISIS as it officially established itself in the shattered North African state. Fox News would report in its article, “Herridge: ISIS Has Turned Libya Into New Support Base, Safe Haven,” that: [Catherine] Herridge reported that one of the alleged leaders of ISIS in North Africa is Libyan Abdelhakim Belhadj, who was seen by the U.S. as a willing partner in the overthrow of Libyan dictator Muammar Gaddafi in 2011. “Now, it’s alleged he is firmly aligned with ISIS and supports the training camps in eastern Libya,” Herridge said. It is clear that despite Western claims that regime change in Libya would be the beginning of the end for Libya’s violence and instability, it was only the end of the beginning – and not only for chaos in Libya – but for other nations across North Africa and in Syria itself. Using Another 9/11 to Justify Creating Another Libya NATO’s intervention and regime change in Libya did not avert a refugee crisis, it helped create one. NATO’s intervention and successful regime change in Libya did not make the region or the world safer, it turned the entire nation into a breeding ground for terrorist organizations with so-far unprecedented reach and operational capacity. NATO’s goals in Libya did not prevent the refugee crisis, it helped start it. And with all of this in mind, having seen this and taken full stock of Libya’s outcome, the West has nonetheless moved forward with precisely the same agenda in Syria. In all reality, the West has no intention of bringing peace or stability to Syria. Their goal is to leave Syria as divided and destroyed as Libya, and to use the chaos and instability fostered there as a springboard for other targets of the West’s proxy warfare – most likely Iran, Russia, and targets deeper in Central Asia. The West promises that it will end the chaos in Syria, just like they promised it would end in Libya. It will not end in either. With Libya’s fate in mind, and a repeat performance clearly taking shape in Syria should the West get its way, it must be made clear that no matter how many innocent people are killed by terrorists the West itself helped create and perpetuate, they will not get an opportunity to turn Syria into the “Libya of the Levant,” no matter how convenient and well-timed these killings are, no matter how deep they are within the heart of Europe or North America, and no matter how tragic and regrettable the aftermath is. Tony Cartalucci, Bangkok-based geopolitical researcher and writer, especially for the online magazine“New Eastern Outlook”.In this instructable you will learn how to make a Q&D-Poor man's-Skinner-Sadist-Jeopardy game . First off, the disclaimer: I'm not responsible of whatever you do. You have to know that with a great power comes...bla-bla-bla. Just be careful and remember that electricity reserves respect. While the energy involved in this project is generally safe, it can be fatal (or at least very harmful) given certain ... While being a bit lengthy and requiring experience with Arduino, this contraption is bound to grant you infinite glory among your friends, toddlers and grownups alike! Step 1: What You Need Here's a list of the materials and parts I used: The Frame * 5 x 4-feet long rectangular profile (0.5" x 0.5") pieces of wood, as solid as possible. Although you could probably get away with plywood if you wanted to, I a ... Update! See Step 32 to find out how to use this project with a green laser! Also - checkout the LaserTweet Instructable to make this project display data from Twitter: http://www.instructables.com/id/LaserTweet-Twitter-Projecting-Laser-Show/ This project uses an Arduino and some cheap audio speakers to create a real laser show with full X and Y axis control. The included source code lets you easily draw tex ... For the Smart Cities exhibition in Leeds in a couple of weeks, we’ve been building a physical representation of an agent based simulation. Hex Bug Spiders are relatively cheap hexapod robots that are controlled via an infra-red transmitter which has an A or B code so that you can control two simultaneously. The way it walks is referred to as the Jamius walking mechanism after its inventor (see: http://www.y ... Idea: To take one of my old Playstation 1 controllers and extract the dual thumbstick setup so that it can be easily used in a microcontroller project (in my case: with the Arduino) without extra libraries or drivers that you would need if you want to use the entire controller. Please let me know what you think or if you have questions/criticism for me! I'm always looking to learn new things.Required materi ... Make A "doorbell" using an Arduino Uno, a Wave shield from Adafruit, a small speaker, a plug, a Sharp distance sensor and a Shaun the Sheep. Our Shaun is used in an open doorway to alert store staff when a customer has entered. Step 1: Parts List 1. Wav Shield Party Pack (includes speaker and SD card) - $35 2. Arduino Uno - $30 3. Power plug - $7 4. Sharp Distance Sensor - $14.95 5. Shaun the Sheep found o ... I bought this skull to decorate my computer desk. However, analyzing better, I could do something more interesting. I hope you enjoy. Step 1: Materials - A plastic skull - 8 screws; - Microcontroller (I used an Arduino board); - A Protoboard - A nunchuck (for nintendo wii control) with a adaptador Note: I bought the adapter but can be easily made by following this step by step: http://www.instructables.com/ ... Welcome to my 3rd Instructable everyone ! Today we're going to build a 'device' to control a mini-sized helicopter with a Wii Nunchuk. The helicopter that we're using is a cheap (26$) 3-channel (yaw, throttle, pitch) helicopter that I bought a 1 month back from Dealextreme.com . I can say that it is a VERY durable heli : I have crashed more thant 100 times and it's still working ! It is not radio-controlled ... I just hope every body's heard. The Bird is the Word! This is a simple device to play Surfin Bird really loudly when someone trips off the motion sensor. If you don
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11088, 1783, 273, 253, 9400, 285, 3762, 326, 6284, 479, 1060, 15, 4683, 2282, 13, 6747, 476, 247, 11098, 16555, 16222, 281 ]	zitane (TAIW) with nitrosonium tetrafluoroborate in sulfolane to form 4,10-dinitroso-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazaisowurtzitane (TAIW(NO)2). The 4,10-dinitroso-2,6,8,12-tetraacetyl-2,4,6,8,-10,12-hexaazaisowurtzitane (TAIW(NO)2) in turn was treated with nitronium tetrafluoroborate in sulfolane to give the explosive, 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW). These flouroborate reagents are very expensive and, additionally, disposal of left-over waste is very costly because of the presence of fluoride.Tag: soft squidgy goodness When was the last time you recommended a book by saying any of the following? . “Boy, the grammar was spot on – what a read!” “Most of the dialogue was just like real life.” “There were literally no plot holes – I totally believe that situation, or something very similar and just as cohesive, …Canadian Crypto Businesses Now Regulated as Money Service Businesses (MSBs) Canada Crackdown – The Canadian government just announced that going forward it will regulate any businesses “dealing in virtual currency” as Money Services Businesses (MSBs). This move is aimed at protecting Canada’s financial ecosystem from potential terrorist financing activities and money laundering. Canada considers money service businesses as those that handle money, but are not ‘official’ chartered banks; such as money transfer services and foreign exchange services. The report states: “Persons and entities that are “dealing in virtual currency” would be financial entities or other entities deemed domestic or foreign MSBs, as the case may be. As required of all MSBs, persons, and entities dealing in virtual currencies would need to implement a full compliance program and register with FINTRAC.” Under FINTRAC (Financial Transactions and Reports Analysis Centre of Canada), these companies are required to have a complete Know Your Client (KYC) and Anti-Money Laundering (AML) policies, procedures, and reporting. These businesses are also required to report any suspicious activity on their platform, immediately. The Canadian government believes that these new amendments prevent money laundering and terrorist activities, while not holding back potential innovation. If these new amendments are fully accepted, they will come into effect exactly 12 months after their registration – no need to panic. >> Operation Crypto Sweep Crypto Regulation Front-Runner According to IMF analysis, Canada is known as one of the most financially stable nations in the world. The country avoided major bank shutdown during the Great Recession of 2008, in the U.S. Much of this stability was from tight regulations and strict reporting for MSBs and chartered banks. Just recently, a number of Canadian banks followed suit of the U.S. Banks and banned their customers from buying cryptocurrency via their banks’ credit cards. The Bank of Montreal (BMO) even went as far as banning crypto purchases via Interac E-Transfer. Last Month, Canadian Government also took part in “Operation Crypto Sweep” in which the North American Securities Administrators Association (NASAA) sent 70 cease-and-desists letters to operations running in the U.S. and Canada that they believe were running scam cryptocurrency companies. Later it was found that all ICOs operating within Canada were found ‘fraudulent.’Trechus subnotatus Trechus subnotatus is a species of ground beetle in the Trechinae subfamily. Description Beetle in length from . References Category:Beetles described in 1831 subnotatusMonthly Archives: March 2015 Guess what, people. You get to practice your religion up to the point where you infringe on someone else’s life. That’s it. That’s the cut off. That is as far as you can push your religion. (In fact, that is as far as you can push anything you want to do.) That’s all “religious liberty” means. Because if you can force your religion onto someone else, then they don’t get to take part in this “Freeedom of Religion” the Framers thought so important that they put it into the very First Amendment. Guess what else, people. “Religious liberty” is not under assault. Not in any way shape or form. What is “under assault” — a horribly inaccurate term if there ever was one — is the privilege Christians have had until recently to force their religion on other people. It really is as simple as that, and I dare someone to prove otherwise. I am not an economist. I was a software engineer who decided to become a stay-at-home dad/Household Manager. I had no course on Econ while in college. I had a high school understanding of supply and demand. A few months ago, I picked up “An Idiot’s Guide to Economics”. So, Men’s Rights Advocates are mostly horrible people with a highly mistaken view of reality. I admit, however, that there are a couple-few places where work could be done in the area of helping men. The courts when dealing with fathers, while getting better, could probably be even more egalitarian. Men could use their own shelters when they are the victims of DV. The rate of incarceration of men, especially men of color, may be far higher than they should be in relation to women. (Yes, I used some weasel words — I’m trying to be charitable to a generally terrible group of people.) Perhaps there should be an organization that works towards fixing these inequities. So, men who are feeling lost, unsure, threatened and violated, complaining on the internet should help you out just fine. It’s not like a Google search for “Men’s Shelter” might give you someplace to go if you are in trouble, and maybe a place to donate time or money to help out Men. I didn’t link because Google is good at knowing where you are and my search is not your search. I’m sure that Google really has no response for any other men’s issues, too. I really have no other response than what David at We Hunted the Mammoth has already said — A Voice For Men has set itself up as the premier site for Men’s Issues and they have no plans to do anything for men. As the title says, this has been a tough winter. Not really in the snow department until lately, but in the cold department. Again. Last year’s temps were no better. The only problem with snow, until a few days ago, was that it wouldn’t leave because we stayed below freezing for a long time. That big storm hit the other day and now we have a lot of snow left because of the cold. I am not going to get to go to the Philadelphia Flower Show this year — first one I’m going to miss in 4 years. I had forgotten it was happening already, and then we had a sick son and then ice one morning and snow another. It was not conducive to getting out of the house this week, not even to the supermarket. Spring cannot get here fast enough. Played a lot of the video game Destiny the past couple of months. I like it a lot, though I am now at a point where I’m not getting any better. The story line you play through makes very little sense. Still, I like it. Got a new laptop several weeks ago and finally got Daz Studio and all my content moved over. I can get back to putting together some renders, and maybe some of them will actually be good. I hope to get my camera out for some pictures, too. And I keep meaning to get back to practicing guitar. So I hope my artistic side can be exercised over the next few months.Hopefully I’ll be back before a whole month passes.It is with a heavy heart that I mourn the loss of Lebbeus Woods. He was a tremendous inspiration to me in my pursuit of architecture, and I was incredibly fortunate to work closely with him over the past year. Our long conversations at his table will forever illuminate my mind. His visionary work will continue to influence the discourse for countless years to come. I dedicate the exhibition Field Conditions to him and his enduring legacy. – Joseph Becker Can there be architecture without buildings? What if a wall or a floor went on forever? The works in our current show, Field Conditions, pose these questions and more about the construction, experience, and representation of space. In an attempt to expand our general interpretation of architectural ideas, its focus is on an array of projects by both artists and architects that redefine the relationships between invisible and visible, figure and ground, finite and infinite. As an exhibition, Field Conditions feels like the tip of the iceberg to me, a leaping-off point for further investigation and analysis on these intersections between art and architecture practice and the abstract concept of “space” as a subject. The SFMOMA presentation, with 13 projects by 11 artists and architects, is of course limited by the physical factors of the gallery and as such cannot begin to be a complete and comprehensive analysis of the topic and theory that interests me here. Of course, neither can a singular essay devoted to
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751, 359, 452, 5728, 13, 1333, 13, 14150, 22089, 13, 533, 253, 1375, 556, 574, 697, 4344, 3894, 273, 17122, 19944, 13223, 46037, 32912, 689, 253, 1107, 1955, 281, 247, 572, 11131, 273, 9129, 37756, 13597, 896, 281, 672, 1199, 273, 752, 310, 1024, 6112, 369, 6107, 407, 271, 9129, 6150, 15, 1284, 253, 6150, 1268, 9461, 13, 253, 2659, 369, 6107, 342 ]	ations and used them to debunk the whole notion of a yeti. Annoyed but undeterred, Slick turned his attentions to another reported man-ape creature, this one said to be living deep in the woods of the Pacific Northwest: Sasquatch, often referred to as Bigfoot. That we know anything at all about Tom Slick's search for the yeti and Bigfoot is due almost entirely to Coleman's efforts. A cryptozoologist himself, Coleman spent the better part of thirty years researching Tom Slick's life, particularly as it related to his contributions to cryptozoology. The result was his 1989 book _Tom Slick and the Search for the Yeti_. Coleman wrote in the introduction to his book: "This man would throw his fortune behind a serious search for the mysterious creatures. Who was this man? He was a handsome, lean, prematurely white-haired man, soft spoken, with a slight Southern drawl. Tom Slick was his name, more fictional-sounding than real. And in many ways, Tom Slick's life was the stuff legends are made of...Tom Slick was given many names during his short, event-filled life. But today, hardly anyone remembers him. And that's a shame." Like his father, Slick died when he was forty-six. A plane he was riding in exploded over Montana in 1962. Had he lived, Tom Slick might have hooked up with or even founded the Texas Bigfoot Research Conservancy, which carries on Slick's interests in Texas. The Texas Bigfoot is believed to be a southern cousin of the Pacific Northwest's Sasquatch. Of the one hundred or so sightings reported on the center's website, the center deems about seventy-five of those sightings as legitimate in the way that sightings of unidentified flying objects are legitimate; both remain unidentified. Persistent reports of a Sasquatch-like creature living along the Sulphur River, just across the state line in Arkansas, inspired the movie _Legend of Boggy Creek._ The modern-day Texas Bigfoots (Bigfeet?) go by many names, some of which sound like high-end fishing lures: Night Screamer, Hawley Him, Haskell Rascal, Wooly Bugger and Caddo Critter. The people at the Texas Bigfoot Research Conservancy believe that the sightings indicate a primate, albeit an elusive one for which no remains have ever been positively identified. Recent sightings have occurred in the Sam Houston National Forest, near the San Jacinto River. We might say that all of this started with Tom Slick, but to call him Texas's first cryptozoologist we would have to dismiss the Comanches, Tonkawas and other Texas tribes who believed strongly in a man-ape creature in the same way that they believed in, say, bears. The Hill Country has had a few sightings, too. One came in 1902 in a cedar chopper community called Panther Path in Travis County. A group of young people were fishing and hunting in the area above the old McDonald Dam when a hairy, eight-foot-tall man confronted the young sportsmen with a large club, the better to pulverize them. Bigfoot let loose a bloodcurdling scream and advanced in what can only be described as a menacing manner toward the terrified young people. They ran for the wagons and barely made it. Bigfoot followed them for a while before giving up and disappearing into legend and lore. Bigfoot was the target of many a Hill Country hunter for a while after that, but neither hide nor hair was seen of the creature again. If only Tom Sick and his team had been there! But I may be doing Tom Slick an injustice to focus solely on his searches for abominable snowmen, Bigfoot and several other perhaps mythical creatures. This was a man who founded what is today the Southwest Foundation for Biomedical Research, the Institute of Inventive Research, the Southwest Research Institute and the Mind Science Foundation. Much of the work he founded continues today. Slick helped develop Brangus cattle and at one time had one of the three largest herds of Angus cattle in the country. Following in the footsteps of his wildcatter father, he discovered the Benedum Field in west Texas, one of the largest oil strikes in the United States after World War II. Most of us don't have any reasonable expectation of having Tom Slick's resources or of leaving such a legacy. What most of us have in common with Tom Slick is that we, too, want to know, once and for all, if there is or ever was such a creature as the yeti or Bigfoot. Like Tom Slick, we just want to know. ### THE PLIGHT OF THE PLEUROCOELEUS We don't usually think of dinosaurs when we think of Texas. We might think about the state's officially designated large mammal, the longhorn, or the state small mammal, the armadillo. We know that the state bird is the mockingbird, the state tree is the pecan and the horned lizard (or horny toad, as most of us call it) is the state reptile. Rock hounds might even know that the state stone is petrified palm wood. Seldom is heard a word, discouraging or otherwise, about the state dinosaur, the pleurocoeleus. The pleurocoeleus is the official state dinosaur of Texas. Whether Texas actually needs a state dinosaur is open to debate, but the pleurocoeleus ( _Brachiosaur sauropod_ ) was so designated by the state legislature 1997. It's our dinosaur, by golly, and we're Texans, so we're going to be proud of it, even if it wasn't what you might call ferocious. You might think that Texas would have adopted a carnivore, but our dinosaur was a strict vegetarian. At least it was big—about fifty feet long and weighing in at about twenty tons. Paleontologists tell us that despite its size, our dinosaur was decidedly mild-mannered. Fight or flight? The pleurocoeleus probably didn't have to give the matter a lot of thought. We can watch and listen to mockingbirds, pick pecans and we know a longhorn cow when we see one and an armadillo, which we can't always avoid when they try to cross the road. The pleurocoeleus hasn't been seen in these parts for, oh, about sixty-five million years, give or take a few million years either way. But we have proof that they lived here. Near Glen Rose, at the appropriately named Dinosaur Valley State Park, on the banks of the Paluxy River and in the riverbed itself, are some remarkably well-preserved pleurocoeleus tracks. These are some of the best dinosaur tracks in the world, which is why paleontologists love the park and have ever since Roland T. Bird of the American Museum of Natural History visited the site in 1938. Bird realized that a set of double tracks showed an herbivorous sauropod—most likely our boy, the pleurocoeleus—being chased by a meat-eating carnosaur. This was the first time sauropod tracks had been discovered anywhere in the world, which caused no small amount of excitement back in New York. The Glen Rose tracks were duly sent to New York and displayed at the American Museum of Natural History. The pleurocoeleus obviously couldn't get away from the site fast enough on that particular day, but since then its tracks have been scattered hither and yon, to the Texas Memorial Museum in Austin and, unfortunately, into the private residences of many amateurs—or vandals, depending on how you look at these things. The dinosaur tracks are a major wonder, but it's a small wonder that any tracks are left here at all. People complain that all the "good" tracks have been removed from the Paluxy River Valley. A woman in Glen Rose told me that a lot of area families have a quarried dinosaur track or two in their homes. "You usually see them on people's living room wall," she said. It took a special set of circumstances to preserve the tracks for all these millions of years. Scientists believe that a violent storm blew across the shoreline a few days before the tracks were made and created a series of sand- and lime-laden mudflats. A herd of pleurocoeleus came ambling across the sticky and still-wet mud in search of a primordial salad, followed in interested pursuit by the carnosaurs looking for some fresh sauropods; the pleurocoeleus qualified. True to their pacifistic nature, the pleurocoeleus tried to run away, but we don't know if they won that particular footrace or not. No intact skeleton remains were ever found, just huge saucerlike depressions from their hind feet and smaller tracks, much like horseshoes, from their front legs. The primal, existential struggle for food and survival was preserved in stone when the seashore turned to stone, leaving behind the rocks we see in the park today, including the ones with the dinosaur prints. We in Texas have never collected dinosaur fossils like we have collected, say, arrowheads, but the state has had its fair share of fossilized dinosaur discoveries over the years due to a quirk of ancient geography dating back to when much of what is now Texas was covered by an ancient sea. As the sea level rose, the land was covered with
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11990, 253, 43841, 273, 776, 17772, 13, 347, 2167, 253, 3846, 4035, 281, 3153, 13, 25189, 18685, 275, 3095, 2010, 457, 84, 2133, 15, 187, 187 ]	researcher/consultant/trainer/presenter, not a practitioner – getting practitioners to speak in their own language works really well). It leverages and demonstrates the social and collaborative qualities of the Second Life platform. There were some hitches on the day (aren’t there always with presentations in Second Life?!), and Jo was called away to attend to something else so couldn’t be in-world to assist as she normally would have, but overall I felt that this presentation worked a lot better than the Go Virtual 07! one. As for images there are only a few, with Konrad Glogowski taking a few screenshots, and Alan Levine taking this one and this one. These pictures only show the section of the presentation held on Jo’s personal island – illustrating the need to organise thorough documentation of an in-world event to give a more accurate impression of what happened. Both Jo and I will continue to explore the ideas discussed in the post. (That’s her in the picture above supporting my Go Virtual 07! presentation – thanks again Jo!) I enjoy using Second Life as a presentation platform, and I will be taking the many lessons learned during my experiments and continue to develop my presentation style. Visit the presentation in the sky Finally, the ‘Virtual Worlds – Trends and Opportunities’ presentation for Go Virtual 07! on the sky platform will be there for a while (until we need the prims for something else!), so if you get a chance, check it out. We put a heck of a lot of work into it, and it’s a bit of a shame that not many people have seen it yet – an issue this blog post, in part, is intended to hopefully rectify. To find the presentation you need to go to jokaydia’s landing point, look for the Teleporter sign and select Sean FitzGerald’s Virtual Worlds Presentation. Jo and I are pleased with how well it went, especially since it was our first event. There were a few of the usual technical glitches that we come to expect in Second Life, and we learned a few lessons for next time, but overall we think it was a great success. We actually maxed-out the sim at 40 avs and had several people trying to get in throughout the event! One thing I think worked well was mixing up the media. We alternated slide presentations with videos, and one presenter used an oversized Thinc book. It made for a very multi-media event. We had intended to use streaming audio, but as we were about to set-up we found someone else had pirated our rented Shoutcast server! It wasn’t such a bad thing though – only a few presenters wanted to use voice and it would have added another variable to an already challenging session. Thanks to all those who presented and provided videos. And a special thanks to Corwin Carillon for dealing with a flood of newbies’ questions in IM… asking them to send him their questions worked a bit too successfully it seems! Overall, the presentation seemed to go quite well, although it’s always hard to tell with presentations in Elluminate. I didn’t pay any attention to the chat channel… I focused on the presentation while Jo did a great job of fielding questions in chat. I always encourage chat – I like having a back channel going on. I like it that people are having rich conversations provoked by the topic that I am presenting. It’s great to see people sharing resources and helping each other out too. I fluffed my punchline a bit. I wanted to finish up by making a point about the need for educators to pay attention to virtual worlds, or they will no longer be relevant in the eyes of Net Gen students who are growing up completely accustomed to avatarised environments. I took the risk of using a famous clip from the South Park episode where the boys are represented playing World of Warcraft to illustrate this point. The language in it is very ‘blue’, which is typical of South Park, but the clip is funny, and I think it does a great job of illustrating the danger of teachers (and other adults) coming to be seen by the Net Gens as “artards” (r-tards… gamer speak for retards) for completely misunderstanding what young people are doing online, and the value of online interaction for them. My intention had been to shock, but not offend. I wasn’t sure whether I was going to use the clip right up until the end, but the audience seemed pretty receptive up until that point, so I decided to let it rip. Unfortunately, between being tired and nervous, and feeling rushed as we were running out of time, I didn’t get a chance to actually say: “The last reason I think educators need to pay attention to virtual worlds is so that our students don’t think we’re artards.” In the rush I also didn’t give a blue language warning, which I regret, and to make matters worse the the clip kept looping! Several people seemed offended, which is understandable, but I think most people got the point. Anyway… if you get chance check out the presentation resources – there is a lot there to explore about what’s happening in the virtual world space. There is currently an explosion in the number and population of online 3D virtual worlds. This development could even be heralding the next evolutionary phase of the Internet – the 3D web. This session will provide an overview of the latest developments in online 3D virtual worlds and describe some of their unique characteristics. We will also look at how these environments can be used in education and how they can help explore new learning models. We will look at why it is important for educators to pay attention to online 3D virtual worlds and become involved in their development. The session will focus on Second Life, one of the more popular and flexible online 3D virtual worlds. Outcomes At the end of the session participants will have an understanding of the following questions: What are online 3D virtual worlds? How popular are they becoming? What are some of the characteristics of online 3D virtual worlds and what new opportunities do they present for online education? What are some of the ways online 3D virtual worlds can be used in education? What are some of the challenges educators face when using online 3D virtual worlds? Why do educators need to pay attention to online 3D virtual worlds? What does the future hold for online 3D virtual worlds and the 3D web? Jo Kay (aka jokay Wollongong) and Sean FitzGerald (aka Sean McDunnough) will host an event within the 3D online virtual world of Second Life, showcasing some of the Australasian educational projects currently being undertaken using the Second Life platform. A number of educators from Australia and New Zealand will give brief overviews of their educational activities within Second Life. After the presentations there will be an opportunity to explore some of the educational spaces and projects featured. Participants will be provided with landmarks and in-world resources to assist them to further explore the educational uses of Second Life in the future. Outcomes At the end of the session participants will have an understanding of: A number of projects currently being undertaken in Second Life Some possible educational uses of Second Life How Second Life can be used for online presentations and web conferencing Share this: Like this: Sean FitzGerald I am an independent researcher, consultant, trainer and presenter with an interest in emerging technologies - particularly social media and virtual worlds - and their impact on society. I'm interested in exploring how we can use these technologies to transform individual and collective consciousness so that we can better deal with the serious challenges facing humanity and help create a just and sustainable world.Culture Blog While so much in British politics is on hold to avoid leaving Europe, the government are proceeding with plans to make all bodies the possession of the State. In a short time, we will be presumed to be organ donors unless we take the trouble to opt-out: This has been the law in Wales for the last 3 years, so that those of us visiting Wales for the day have been in an ambiguous position: if there was a terrible road accident, would they check whether we were resident in Wales before taking our organs or after? The opt-out is available (https://www.organdonation.nhs.uk/register-to-donate/refuse-to-donate/refuse-donation-form/) but it is not fool proof. Before my brother had his tumour removed ten years ago, the consultant surgeon reassured my parents that he would under no circumstances remove his leg on the operating table; but before going under the anaesthetic, alone, my brother had to sign a disclaimer allowing the surgeon to do just that if he deemed it to be necessary. The tumour would not have been removed if he had not signed to allow them to take his leg as well. There is nothing to stop people being put over a barrel in the future, that if we do not agree to have our organs harvested at death then we will not be treated in life. The BBC is not just complicit in this matter but aggressively so. Their propaganda is that those who donate organs save lives, they are saviours. We are told that by our death we can save other people and that such a selfless act will ease the mourning of our relatives, as though the dead continue to live, resurrected in someone else’s body.
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296, 1170, 6345, 13, 285, 40738, 4925, 323, 253, 7223, 15, 1292 ]	serious expression turned decidedly less so. "If I'm not mistaken, Roland, I believe you just said I was . . . over the hill." Reacting to the spark of playfulness in her features, he laughed. "If you're over the hill, Lizzie, then I've already got one foot in the grave." He looked down at his legs. "Oh wait . . ." He laughed. But she only smiled and eyed him. "I'm so very grateful you lived." Her eyes lit with a sparkle that precious stones would envy. "And that you got to keep your leg." "And that, my dear Lizzie—" On impulse, Roland reached out his hand, much as he might have done if he were attempting to stroke a skittish doe. And to his surprise, she met him halfway. "That is completely due to you keeping your promise. For which I will forever be grateful." He gently tightened his hand around hers, and the light in her eyes deepened. But too quickly for him, she pulled her hand away. And he reminded himself again, _Friendship. Only friendship._ She reached into her pocket and pulled something out. A thin bundle of letters, he saw upon closer inspection, tied with string. "I'd like to show you something," she said. "And get your opinion, if I could." "Letters from a secret admirer?" he asked, forcing humor into his voice. "No," she whispered, not looking up. "These belonged to a soldier who was here at Carnton. A boy. He was no more than thirteen or fourteen years old." She handed them to him. Sobered, he turned the thin bundle in his hand. "There's no address." "I know. So I have no idea where to send them. Or if Thaddeus wrote them. Or if they were written to him." "Thaddeus?" "I found the name written on a page torn from a Bible. It was with the envelopes in his pocket. But there was no last name. I asked Colonel McGavock this morning if he would check with the War Department to see if they could look up his first name to learn his last. He said he would contact them for me. But look at the string, Roland. It's tied in a knot. Who knots a stack of letters they intend to read again? And for some reason, I can't bring myself to cut it. It feels wrong somehow. Like I'm trespassing. Or maybe there's something in there I shouldn't be privy to." He smiled at her. "Now you sound like a character from a mystery novel. I seriously doubt there's anything a boy that age would commit to paper, much less carry around with him, that would be too unseemly." She leaned forward. "There's something else. It's what he said to me at the very last, right before he died." "Now you really are sounding mysterious." She briefly closed her eyes. "He said, 'Mama' . . . I think he must've thought he was speaking to her. He said he'd grieved over how he'd left things between them, but that he didn't take it with him like he'd apparently told her he had." "He didn't take what?" She shrugged. "That's just it. I don't know. He didn't say. But whatever it is, or was, he said he left it there, buried beneath 'the old willow tree.' And then, right before he died, he whispered, 'Somehow it makes dying easier, knowing you'll have it.'" Roland said nothing for a moment, then sighed. "Well, that certainly sheds an interesting light on things, doesn't it?" She nodded, staring at the bundle in his hands. "I think that's why I haven't been able to read these. I feel such a . . ." "Burden?" he supplied. "Yes. And also a responsibility. But the fact that the string is knotted tight . . ." She eyed it as though it were a living thing. "It doesn't make sense, I know." "Do you think maybe one of the doctors gave the boy some medication that caused him to become delusional? Maybe he was speaking nonsense." She shook her head. "The doctors weren't administering medicine to anyone who didn't stand a good chance of living. And he did not." What she said about medication not being administered haphazardly was true. They hadn't even offered him any, until Dr. Phillips ordered it. She looked down at her hands in her lap. "All I know, Roland, is that I can't cut the string. But . . ." She slowly lifted her gaze. "Maybe you could." He raised his brows. "So let me get this straight. You want me to cut the string and open the envelopes so that whatever curse you apparently believe is going to befall the poor, unsuspecting soul who does such will settle on me instead of you. Is that what I'm to understand?" The tiniest smile crept over her face, and she nodded. "Yes. That's pretty much the gist of it." He eyed her for a moment, then gestured. "Hand me that knife on the table over there." C HAPTER 19 Roland sliced through the knotted string binding the stack of envelopes, sensing Lizzie's trepidation. But being a soldier himself, and carrying his own bundle of letters, he felt at ease with what he was doing. He withdrew the contents of the first of three envelopes and began to read. The handwriting was rather slapdash, so the words were difficult to decipher. "What?" Lizzie whispered, leaning closer. "You're frowning. What is it?" Hearing her increased concern, he couldn't resist egging her on a bit. "Mmmm . . . Lizzie, this is bad." She reached out. "What does it say?" Her hand on his bare arm sent a small thunderbolt through him. It took concentration to continue reading. "It says . . . 'Hayrides. Walks by the creek. Warm biscuits on Sunday mornings. The smell of snow. Melvin, when he burrows down deep beneath the covers with me.'" He lifted his gaze and caught her droll look. "It's some sort of list." Smiling, he scanned the wrinkled, stained piece of paper, then turned it over. The handwriting filled both front and back. He handed it to her, and she read silently, her lips moving. Softness swept her face. "I think it's a list of things he loved." She fingered a dog-eared corner, her tone almost reverent. "Sunsets painted orangey red. A fresh ticked bed and a warm blanket. The feel of mud between your toes come summer. Rain as it sluices off the metal roofing. Mist as it hangs over the hills." Roland loved watching her. She possessed a kind of beauty that only seemed to deepen the more he got to know her. Features he'd thought comely upon first glance—her full lips, the slight up-tilt of her pretty nose, the womanly curves that not even the simplest blue day dress could mask—he now found intoxicating. She finally folded the letter, and he held up the other two envelopes. "Should we?" he asked. She nodded, but made no move to take them. "Since I'm the one already cursed . . . ," he said beneath his breath, satisfied when the comment drew a soft laugh. He opened the second envelope and withdrew a piece of paper similar in appearance to the first, with the same scrawled handwriting. "This one says . . ." Tempted to tease her again, he read the first few lines and all humor fell away. He cleared his throat. "You were right, Mama. This undertaking of mine is far more egregious than my thoughts ever could have conjured. I am not as brave as I once thought myself to be. Before battle commences, in those eternally fleeting moments before the first shot is fired, my bones all but shake free from their joints, and I do not know how my body holds together. I am thoroughly run through with fear. And I am ashamed of being afraid. But I am not the only one. I have seen grown men . . ." He stopped reading aloud. Not that Lizzie would have been offended by the boy's description. He'd witnessed firsthand all she'd been through since the battle that night, and he was convinced there was nothing this woman couldn't endure with grace and dignity. Rather, he'd witnessed the same things the boy was describing and it had moved him just as deeply. She gently tugged the pages from his hand. "'I have seen grown men,'" she continued, her voice a whisper, "'lose the contents of their stomachs, and worse, as the first blast of a Napoleon gun sends a cannonball screaming for the front line. Some men are very shaky. Often they take off running the other way. I have seen more than one officer use his revolver on his own men as they seek to retreat before the battle is fully begun.'" She drew in a slow, painstaking breath, and Roland reached for the pages. But
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particles in the chain is characterized by a binary random variable (this can be, for example, particles with the spin $\frac{1}{2}$). In the aforementioned model it is assumed that spins next to each other are almost always aligned in the same direction. The only exceptions are assumed to be $d$ cases in which the neighboring spins are antialigned. In this model the number of states grows as a power-law, with the corresponding index $q$ being $q_{\mathrm{stat}}=1-1/d$. In addition, the distribution of the total spin of the system in the limit of $N\rightarrow\infty$ tends to a $q$-Gaussian with $q_{\mathrm{dist}}\neq q_{\mathrm{stat}}$. All models in [@Moyano2006; @Rodriguez2008; @Ruseckas2015], except the last model of [@Rodriguez2008] are for $q\leq1$. The distributions of the non-extensive statistical mechanics can be obtained from mesoscopic description of the systems in the form of probabilistic dynamics [@Tsallis2009-1]. Such probabilistic description can be provided by nonlinear Fokker-Planck equations and corresponding nonlinear stochastic differential equations (SDEs) [@Borland1998; @Borland2002], SDEs with additive and multiplicative noises [@Anteneodo2003; @Santos2010] or with multiplicative noise only [@Queiros2007], and with fluctuating friction forces [@Beck2001]. Nonlinear SDEs generating distributions of non-extensive statistical mechanics together with $1/f$ noise have been proposed in Ref. [@Ruseckas2011]. Scaling law that follows from nonlinear Fokker-Planck equations has been recently experimentally confirmed in granular media [@Combe2015]. The goal of this paper is to extend the model presented in Ref. [@Ruseckas2015] by introducing stochastic temporal dynamics. Conserving the total number of domains $d$, we allow spins near domain boundaries to flip. This effectively introduces a random walk of domain boundaries into the previous static model. In the limit of large number of spins we derive the Fokker-Planck equation and a corresponding SDE describing the temporal dynamics of the total spin of the system. The proposed dynamical model provides an insight how a mesoscopic dynamics characterized by the non-extensive statistical mechanics could emerge from a microscopic description of the system. The Letter is organized as follows. To show how stochastic temporal dynamics can be introduced into a model describing the equilibrium, in Section \[sec:uncorrelated\] we introduce stochastic dynamics into a simple model consisting of uncorrelated binary random variables. In Section \[sec:correlated\] we use a similar stochastic temporal dynamics for the model with correlated binary random variables and leading to extensive generalized entropy with $q<1$. In Section \[sec:long-range\] we demonstrate that presence of macroscopic fluctuations in this model can lead to $1/f$ noise, whereas in Section \[sec:subsyst\] we consider properties of a part of larger system. We summarize the paper in Section \[sec:conclusions\]. Stochastic dynamics in the model with uncorrelated binary variables {#sec:uncorrelated} =================================================================== As in Ref. [@Ruseckas2015], we start with the analysis of the dynamical model without any correlations between the particles or their spins. Let us say that we have $N$ particles which have spin projections on certain axis equal to either $-\frac{1}{2}$ or $+\frac{1}{2}$. The microscopic state of such system is fully described by a set of spin projections $\{s_{1},s_{2},\ldots,s_{N}\}$. This system may be treated, in the statistical mechanics sense, using the microcanonical ensemble in which each of the microscopic states is assigned the same probability. Here we obtain the same stationary probability density function (PDF) from the temporal dynamics perspective. We are interested in an observable macroscopic quantity, the total spin of the system $$M=\sum_{i=1}^{N}s_{i}\,.\label{eq:total-spin}$$ Alternatively we can express the total spin as $$M=\frac{1}{2}(N_{+}-N_{-})\,,\label{eq:m-np-nm}$$ where $N_{+}$ is the number of spins with projection $+\frac{1}{2}$ and $N_{-}$ is the number of spins with projection $-\frac{1}{2}$. A sum of $N_{+}$ and $N_{-}$, by definition, should give the total number of spins $N$, $$N_{+}+N_{-}=N\,.\label{eq:n-np-nm}$$ From Eqs. (\[eq:m-np-nm\]) and (\[eq:n-np-nm\]) we obtain relation between total spin and number of particles having certain spin projections: $$N_{+}=\frac{1}{2}N+M\,,\qquad N_{-}=\frac{1}{2}N-M\,.\label{eq:np-nm}$$ To introduce temporal dynamics we assume that during the short time interval $\Delta t$ each spin can flip with the probability $\frac{1}{2}\gamma\Delta t$. If $\Delta t$ is short enough we can assume that only one spin flip takes place during the time interval $\Delta t$. Since each spin can flip independently, the transition probabilities per unit time are $$\begin{aligned} p(M\rightarrow M+1) & \equiv & p^{+}(M)=\frac{1}{2}\gamma N_{-}\,, \label{eq:prob-p}\\ p(M\rightarrow M-1) & \equiv & p^{-}(M)=\frac{1}{2}\gamma N_{+}\,. \label{eq:prob-m}\end{aligned}$$ The transition probabilities $p^{+}(M)$ and $p^{-}(M)$ define a one-step stochastic process and imply the following Master equation for the probability $P_{M}(M,t)$ to find the value $M$ of the total spin at time $t$ [@Kampen2011]: $$\frac{\partial}{\partial t}P_{M}(M,t)=p^{+}(M-1)P_{M}(M-1,t) +p^{-}(M+1)P_{M}(M+1,t)-(p^{+}(M)+p^{-}(M))P_{M}(M,t)\,. \label{eq:master}$$ For large enough $N$ we can represent the dynamics by a continuous variable $x=2M/N$. Using the standard methods from Ref. [@Kampen2011] one can derive the Fokker-Planck equation from the Master equation (\[eq:master\]) assuming that $N$ is large and neglecting the terms of the order of $1/N^{2}$. The resulting Fokker-Planck equation is $$\frac{\partial}{\partial t}P_{x}(x,t)=-\frac{\partial}{\partial x} [\pi^{+}(x)-\pi^{-}(x)]P_{x}(x,t) +\frac{\partial^{2}}{\partial x^{2}}\frac{1}{N}[\pi^{+}(x)+\pi^{-}(x)]P_{x}(x,t)\,, \label{eq:FP-general}$$ where $P_{x}(x,t)=(N/2)P_{M}(Nx/2,t)$ is the PDF of the stochastic variable $x$ and $$\pi^{\pm}(x)\equiv\frac{2}{N}p^{\pm}\left(\frac{Nx}{2}\right)\,.$$ The SDE corresponding to the Fokker-Planck equation (\[eq:FP-general\]) is [@Gardiner2009] $$\frac{dx}{dt}=[\pi^{+}(x)-\pi^{-}(x)]+\sqrt{\frac{2}{N}[\pi^{+}(x)+\pi^{-}(x)]}\xi(t)\,. \label{eq:SDE-general}$$ Here $\xi(t)$ is a white noise with autocorrelation $\langle\xi(t)\xi(t')\rangle=\delta(t-t')$. When the diffusion coefficient depends on $x$, SDE (\[eq:SDE-general\]) should be understood in Itô convention. For the transition probabilities (\[eq:prob-p\]) and (\[eq:prob-m\]), the Fokker-Planck equation (\[eq:FP-general\]) becomes $$\frac{\partial}{\partial t}P_{x}(x,t)=\gamma\frac{\partial}{\partial x}xP_{x}(x,t) +\frac{\gamma}{N}\frac{\partial^{2}}{\partial x^{2}}P_{x}(x,t) \label{eq:FP-1}$$ and Eq. (\[eq:SDE-general\]) takes the form $$\frac{dx}{dt}=-\gamma x+\sqrt{\frac{2\gamma}{N}}\xi(t)\,.\label{eq:sde-1}$$ As one can see from Eq. (\[eq:sde-1\]), the fluctuations of the macroscopic quantity $M$ decrease with the increasing number of spins as $1/\sqrt{N}$ . From Eq. (\[eq:sde-1\]) follows that the average value of $x$ obeys the ordinary differential equation $$\frac{d}{dt}\langle x\rangle=-\gamma\langle x\rangle\,.$$ Thus the deviations from the equilibrium average $\langle x\rangle_{0}=0$ decay exponentially: $\langle x(t)\rangle
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2491, 273, 475, 46, 15, 31970, 375, 11, 16316, 2193, 313, 19, 15, 20, 283, 1093, 15, 21, 10, 432, 3495, 3382, 13751, 2797, 432, 1458, 3907, 6613, 2470, 1470, 15, 374, 1084, 926, 19, 14, 740, 24854, 25745, 16903, 2270, 31117, 910, 709, 14, 881, 568, 926, 2536, 380, 1594, 1864, 369, 5189, 275, 253, 1072, 13751, 285, 342, 3969, 16316, 2193, 326, 6376, 1561, 247, 13905, 273, 374, 7388, 84, 313, 5229, 2491, 27, 884, 15, 24, 283, 1010, 15, 25, 28, 374, 7388, 2491, 27, 884, 15, 24, 283, 1036, 15, 18, 28, 544, 1470, 15, 374, 1084, 926, 19, 14, 740, 24854, 25745, 16903, 2270, 31117, 910, 709, 14, 881, 568, 926, 2536, 187, 187, 3138, 8486, 2441, 273, 475, 37538, 48978, 31970, 375, 11, 2303, 285, 30398, 4812, 1453, 275, 3382, 13751, 327, 253, 46910, 818, 5388, 5147, 313, 32245, 14826, 15317, 481, 380, 5880, 7887, 313, 5229, 10, 323, 1016, 20204, 310, 17944, 327, 253, 340, 14, 10565, 28, 642, 16316, 2193, 497, 1186, 4713, 1186, 938, 15, 475, 46, 15, 31970, 375, 11, 369, 5189, 689, 247, 2491, 273, 1029, 15770, 10290, 15770, 285, 1698, 14, 10247, 2193, 313, 11958, 34779, 28, 10290, 14, 10247, 2491, 24312, 264, 407, 2806, 24817, 1386, 10, 275, 3307, 3382, 13751, 15, 14263, 1698, 14, 10247, 2193, 497, 5189, 285, 403, 17944, 1840, 253, 2806, 24817, 1386, 15, 380, 7852, 19, 30398, 4812, 1453, 369, 5189, 275, 253, 1072, 13751, 13, 285, 7852, 19, 16316, 2193, 6376, 1561, 247, 13905, 273, 374, 2629, 21492, 313, 27250, 20200, 28, 11978, 17889, 1386, 426, 374, 7388, 84, 17981, 740, 15, 45085, 64, 740, 24854, 25745, 16903, 2270, 31117, 14, 926, 18, 4253, 926, 18, 14, 740, 24854, 25745, 16903, 2270, 31117, 94, 187, 187, 3138, 8486, 2441, 273, 475, 37538, 48978, 31970, 375, 11, 2303, 285, 30398, 4812, 1453, 313, 57, 1864, 10, 275, 3382, 13751, 327, 253, 12597, 39701, 7489, 6542, 5147, 313, 32245, 14826, 15317, 481, 380, 5880, 7887, 313, 5229, 10, 323, 1016, 20204, 310, 17944, 327, 253, 340, 14, 10565, 15, 329, 2491, 273, 1029, 13, 10290, 13, 285, 1698, 475, 46, 15, 31970, 375, 11, 2762, 2193, 369, 5189, 275, 3495, 3382, 13751, 313, 11958, 34779, 28, 10290, 14, 10247, 2491, 24312, 264, 407, 2806, 24817, 1386, 481, 380, 7852, 19, 1594, 1864, 369, 5189, 275, 253, 1072, 13751, 313, 27250, 20200, 28, 11978, 17889, 1386, 426, 374, 7388, 84, 17981, 740, 15, 45085, 64, 740, 24854, 25745, 16903, 2270, 31117, 14, 926, 19, 4253, 926, 19, 14, 740, 24854, 25745, 16903, 2270, 31117, 94, 187, 187, 26102, 16883, 1712, 4674, 1166, 14, 740, 24854, 25745, 16903, 2270, 31117, 94, 187, 22873, 187, 187, 1992, 6583, 326, 475, 85, 2375, 11, 8477, 14, 10247, 13751, 6221, 475, 46, 15, 31970, 375, 2992, 253, 4110, 51, 369, 20068, 285, 27867, 15, 47695, 1877, 273, 253, 4110, 51, 369, 2684, 327, 14034, 475, 85, 2375, 11, 8477, 14, 10247, 13751, 5762, 275, 4240, 285, 4765, 13, 6774, 281, 253, 3302, 873, 273, 11102, 13751, 908, 281, 6642, 10401, 3045, 275, 4022, 15, 17633, 1320, 273, 253, 4110, 51, 8477, 3580, 4950, 326, 11289, 475, 85, 2375, 11, 8477, 14, 10247, 13751, 20714, 247, 2014, 4110, 51, 3961, 387, 253, 38966, 14, 12303, 1979, 3264, 323, 253, 475, 46, 15, 31970, 375, 11, 9128, 15, 380, 5780, 1283, 475, 85, 2375, 11, 8477, 14, 10247, 13751, 20714, 374, 1186, 25002, 28, 581, 387, 253, 1979, 3264, 323, 253, 475, 46, 15, 31970, 375, 11, 9128, 285, 247, 1273, 4577, 3961, 2470, 1470, 15, 495, 1084, 926, 20, 14, 740, 24854, 25745, 16903, 2270, 31117, 910, 709, 14, 881, 568, 926, 2536, 427, 25482, 14, 12496, 8477, 3580, 497, 15134, 285, 497, 3587, 27867, 313, 4739, 273, 253, 48537, 251, 1979, 3264, 323, 475, 46, 15, 31970, 375, 11, 285, 495, 4577, 481, 4683, 253, 11583, 48537, 251, 6430, 3264, 281, 320, 475, 46, 15, 31970, 375, 2992, 47222, 45523, 4950, 326, 11487, 497, 12667, 8688, 15, 23, 6, 8931, 281, 253, 475, 46, 15, 31970, 375, 11, 4110, 51, 3425, 13, 337, 3425, 6096, 1029, 6489, 342, 475, 46, 15, 12366, 375, 9593, 261, 11, 4110, 51, 3425, 13, 285, 253, 5780, 854, 574, 4105, 3425, 3290, 326, 14415, 25038, 8137, 273, 253, 475, 37538, 48978, 11, 3417, 1246, 275, 253, 20204, 15, 380, 475, 46, 15, 31970, 375, 11, 17601, 19, 7372, 9128, 3425, 313, 21996, 36002, 27463, 10, 3797, 495, 13358, 4110, 51, 13, 374, 273, 534, 403, 30092, 14395, 275, 2978, 285, 3894, 2233, 6, 6489, 28, 253, 2626, 4110, 51, 4428, 247, 337, 2613, 16941, 15, 4683, 253, 11487, 6430, 326, 13373, 475, 46, 15, 31970, 375, 11, 4110, 51, 3425, 13, 10523, 273, 841, 497, 2233, 6, 8931, 281, 253, 475, 46, 15, 31970, 375, 11, 17601, 19, 7372, 4110, 51, 273, 30092, 14395, 313, 21996, 36002, 27463, 582, 374, 497, 2233, 6, 8931, 281, 253, 475, 46, 15, 31970, 375, 11, 17601, 19, 7372, 4110, 51, 273, 31605, 14395, 313, 21996, 36002, 27463, 582, 285, 374, 497, 2233, 6, 8931, 281, 253, 475, 46, 15, 31970, 375, 11, 17601, 19, 7372, 4110, 51, 273, 30092, 14395, 313, 21996, 36002, 27463, 10, 3707, 326, 1016, 574, 271, 23851, 313, 47, 10, 2613, 326, 812, 417, 320, 11512, 13542, 15, 380, 8477, 3425, 326, 6096, 1029, 6489, 342, 475, 46, 15, 12366, 375, 9593, 261, 11, 7372, 17601, 19, 3425, 313, 18278, 1093, 1762, 3208, 15, 18, 10, 369, 8931, 387, 30761, 273, 33000, 4110, 51, 6887, 15, 31583, 1783, 273, 253, 495, 4577, 4110, 51, 8477, 3580, 3636, 253, 3361, 273, 475, 46, 15, 653, 360, 507, 11, 313, 2313, 6, 8931, 281, 11854, 47616, 28883, 10, 285, 475, 46, 15, 476, 324, 1215, 11, 313, 783, 954, 1534, 45523, 906, 369, 281, 4097, 520, 2950, 2405, 342, 23309, 273, 23504, 18379, 22925, 28, 841, 374, 8477, 1885, 6430, 497, 8931, 558, 841, 1957, 13751, 342, 18011, 3716, 273, 387, 1878, 374, 475, 37538, 48978, 11, 3417, 15, 187, 187, 3138, 40, 293, 27273, 273, 475, 37538, 48978, 11, 734, 15881, 38590, 2919, 313, 1830, 51, 10, 8477, 3580, 15, 5595, 475, 85, 2375, 11, 8477, 14, 10247, 3382, 13751, 20714, 247, 2014, 475, 37538, 48978, 11, 4110, 51, 3961, 387, 253, 38966, 14, 12303, 1979, 3264, 313, 77, 6597, 337, 285, 374, 10, 323, 253, 475, 46, 15, 31970, 375, 11, 9128, 15, 329, 8578, 273, 475, 85, 2375, 11, 8477, 14, 10247, 3382, 13751, 20714, 374, 1186, 25002, 27, 581, 387, 253, 1979, 3264, 323, 253, 475, 46, 15, 31970, 375, 11, 9128, 285, 247, 1273, 4577, 3961, 313, 77, 6597, 495, 285, 577, 481, 19051, 608, 426, 4016, 17442, 1453, 15, 380, 562, 32848, 24914, 497, 10607, 342, 2233, 14, 12303, 3882, 23465, 313, 32245, 14826, 15317, 17981, 740, 15, 45085, 64, 740, 24854, 25745, 16903, 2270, 31117, 14, 926, 20, 4253, 926, 20, 14, 740, 24854, 25745, 16903, 2270, 31117, 94, 187, 187, 1992, 31986, 253, 16483, 2954, 273, 253, 4110, 51, 6430, 2797, 432, 3382, 13751, 275, 253, 3634, 273, 3786, 7943, 475, 37538, 48978, 11, 3417, 13, 23165, 1783, 369, 2684, 10174, 14457, 21, 14, 740, 24854, 25745, 16903, 2270, 31117, 2947, 14457, 1348, 14, 740, 24854, 25745, 16903, 2270, 31117, 3725, 1777, 1190, 2646, 90, 273, 475, 37538, 48978, 11, 3417, 556, 644, 4232, 1754, 327, 1668, 52, 30509, 6430, 13, 285, 23165, 9959, 403, 4907, 846, 247, 8612, 15443, 390, 3417, 16616, 3614, 1358, 2700, 15, 4066, 695, 1288, 68, 15, 2061, 16, 1374, 16, 26859, 13646, 16, 938, 4590, 37322, 475, 46, 15, 31970, 375, 11, 4110, 51, 6430, 497, 4845, 1561, 253, 475, 46, 15, 2753, 729, 18620, 11, 7368, 13, 1690, 1110, 2797, 432, 3425, 16883, 273, 475, 85, 2375, 11, 8477, 14, 10247, 13751, 313, 455, 11487, 6607, 407, 3425, 346, 43755, 437, 4110, 51, 337, 8375, 253, 475, 46, 15, 31970, 375, 11, 7372, 11957, 423, 267, 16, 41, 854, 2405, 63, 53, 63, 2644, 9128, 3425, 13, 285, 7372, 330, 17364, 2470, 1470, 15, 577, 1084, 926, 21, 14, 740, 24854, 25745, 16903, 2270, 31117, 910, 709, 14, 881, 568, 926, 2536, 475, 46, 15, 12366, 375, 9593, 261, 11, 4110, 51, 6430, 432, 8477, 285, 475, 46, 15, 12366, 375, 9593, 261, 11, 17601, 19, 63, 53, 63, 2588, 16822, 2289, 621, 313, 40338, 9128, 3425, 322, 7414, 47, 4226, 285, 734, 15881, 38590, 3425, 20160, 1093, 1762, 3208, 10, 497, 512, 4441, 275, 253, 475, 46, 15, 19861, 261, 11, 7368, 15, 380, 5780, 4110, 51, 6430, 3413, 275, 776, 1263, 13, 9999, 475, 46, 15, 653, 360, 507, 11, 285, 475, 46, 15, 476, 324, 1215, 2992, 497, 1246, 1561, 253, 475, 46, 15, 2860, 22153, 11, 7368, 15, 187, 187, 3138, 2641, 1190, 15716, 5202, 273, 475, 37538, 48978, 11, 734, 15881, 38590, 2919, 6430, 15, 27452, 552, 6260, 497, 5196, 275, 10616, 7283, 1594, 13, 285, 253, 5202, 369, 22245 ]	between the M. cynos tuf and ITS assays was 0.915 (95% confidence interval: 0.822--1.000). ###### Comparison of Mycoplasma cynos quantitative PCR assays using 71 canine respiratory samples. ![](10.1177_1040638719890858-table1) ITS PCR positive ITS PCR negative -------------------- ------------------ ------------------ tuf PCR positive 33 2 tuf PCR negative 1 35 ITS = in-house M. cynos 16S-23S rRNA intergenic sequence qPCR assay; tuf = newly developed M. cynos qPCR assay. The new tuf assay was further scrutinized using 67 isolates that were characterized by Mycoplasma spp. culture and sequencing. The results identified 5 true-positive isolates and 56 true-negative isolates. The 56 negative samples were comprised of 22 M. canis isolates, 12 M. felis isolates, 12 M. spumans isolates, 7 M. edwardii isolates, and 3 M. maculosum isolates. No false-negatives were found, although 6 isolates were determined to be false-positives because they were positive with the tuf PCR assay but negative by ISR sequencing. Five of the 6 discrepant ISR sequencing results had M. canis and M. edwardii as the 2 top BLAST hits, but included M. cynos in the list of significant hits. Strains of M. canis (ATCC 19525^T^) and M. edwardii (ATCC 23462^T^) were tested and both yielded negative results with the tuf assay. The sixth discrepant isolate was typed as M. maculosum or M. leopharyngis, but also included many other significant hits including several that were excluded by testing the ATCC isolates listed above, thus we chose not to pursue this isolate further. Inhibition monitoring {#section16-1040638719890858} --------------------- Continuous monitoring of the XIC did not reveal any systematic indications of inhibition in respiratory matrix, inclusive of tissues, for 22 clinical specimens tested on 15 independent 7500 platform runs ([Fig. 1](#fig1-1040638719890858){ref-type="fig"}). In these specimens, M. cynos Ct values were 20.6--40.0; the XIC Ct values were 31.3--35.0. The OA assay detected a range of M. cynos Ct values (2.3--18.4) from 23 clinical specimens obtained from 15 independent runs ([Fig. 2](#fig2-1040638719890858){ref-type="fig"}). The XIC was detected in the same specimens and with corresponding Ct values that remained within a span of 2 SDs (Ct range: 10.7--15.8; 2 SD range: 10.7--16.1; [Fig. 2](#fig2-1040638719890858){ref-type="fig"}). ![Detection of Mycoplasma cynos target and exogenous internal control in clinical specimens on the ABI 7500 platform (Thermo Fisher Scientific). The cycle threshold (Ct) for each specimen is plotted on the y-axis; no Ct values were \< 20. M. cynos was detected over a range of high-, moderate-, and low-positive values (black diamonds; moderate-positive range bracketed by black dotted line) in 22 clinical specimens. Five low-positive values were detected and are plotted above the black dotted line. The MS2 exogenous internal control was detected in the same specimens, and MS2 Ct values remained within a span of 2 standard deviations (gray dots; gray dashed line = 2 SDs).](10.1177_1040638719890858-fig1){#fig1-1040638719890858} ![Detection of Mycoplasma cynos target and exogenous internal control (XIC) in clinical specimens on the QuantStudio OpenArray platform (Thermo Fisher Scientific). The cycle threshold (Ct) for each specimen is plotted on the y-axis. A range of high, moderate, and low M. cynos positive values was detected in 23 clinical specimens (black diamonds; moderate-positive range bracketed by black dotted line). The MS2 XIC was detected in the same specimens (gray dots; gray dashed line = 2 SDs).](10.1177_1040638719890858-fig2){#fig2-1040638719890858} Sequence confirmation {#section17-1040638719890858} --------------------- To confirm that tuf PCR-positive specimens contained M. cynos, the ISR was amplified and sequenced. Amplification of the ISR was performed on 107 tuf PCR-positive specimens tested in 2017 and 2018, subsequent to the initial set of 71 specimens used to estimate diagnostic performance in 2016. Visualization of the ISR PCR products revealed that 89 tuf PCR-positive specimens yielded a single ISR band at the 457-bp size expected for the M. cynos genome. The remaining 18 tuf PCR-positive specimens yielded 2 bands; one at the size expected for the M. cynos genome and a second smaller band ([Fig. 3](#fig3-1040638719890858){ref-type="fig"}). Ninety-four PCR products were purified and were directly sequenced (91 of the amplicon size expected for M. cynos and 3 smaller). Of the 91 amplicon sequences expected to be M. cynos, NCBI BLAST revealed that 82 were ≥ 99.6% identical to the M. cynos ISR sequence, 1 sequence shared high identity with M. mucosicanis ISR sequence, and the remaining 8 had poor sequence quality that prevented definitive identification of the Mycoplasma species present in the specimen. The M. cynos 1642 strain genome sequence (HF559394) includes 3 discrete ISR, 2 of which are 257 bases in length and share 100% identity; the third ISR contains a 1 base insertion. Of the 82 sequences that matched M. cynos ISR sequence, 78 of these were 100% identical to the M. cynos 1642 strain ISR of 257 bases (HF559394), 2 were 100% identical to the M. cynos 1642 strain ISR of 258 bases (HF559394), and 2 were 100% identical to the M. cynos 1642 strain ISR of 257 bases (HF559394) except that each had an ambiguous (N) base that could not be resolved manually. The PCR sequence that shared high identity with M. mucosicanis strain 1642 sequence (FM180556.1) was identical at 307 of 309 ISR positions. Sequence analysis of the 3 smaller ISR PCR products identified the presence of M. spumans (100% identical to AF538684) and M. canadense (the most significant BLAST result was to AP014631 with 163 of 169 nucleotide identities; these 2 PCR product sequences were identical); these represent specimens with coinfection of at least 2 Mycoplasma species. ![Gel electrophoresis of Mycoplasma intergenic spacer region (ISR) PCR products. Most tuf PCR-positive clinical specimens yielded a single Mycoplasma ISR band at the 457-bp size expected (lanes 1 and 2) for the M. cynos genome. A subset of tuf PCR-positive clinical specimens yielded 2 bands: one at the size expected for the M. cynos genome and a second smaller band (lanes 3 and 4). Lane 5 = negative amplification control. The outermost lanes were loaded with 100-bp DNA ladder (Thermo Fisher Scientific).](10.1177_1040638719890858-fig3){#fig3-1040638719890858} To visualize the evolutionary relationship of the ISR sequences obtained from clinical specimens in the context of previously characterized Mycoplasma species, phylogenetic analysis was performed.^[@bibr4-1040638719890858],[@bibr24-1040638719890858]^ Phylogeny of Mycoplasma species has been established based on 16S rRNA sequences, and phylogenetic clusters are named after a representative genus or species (<https://www.patricbrc.org/view/Taxonomy/2093>). M. cynos ISR sequences were placed within the M. synoviae cluster, including those obtained from sequence confirmation of tuf PCR-positive specimens (all 82 represented by sequence "Cornell ISR 1"), the M. cynos strain Rosendal/H 831^T^ whole genome sequence, and strain C142 ([Fig. 4](#fig4-1040638719890858){ref-type="fig"}). M. mucosicanis ISR sequences from PCR and M. mucosicanis 1642^T^ GenBank accessions (whole genome sequence SMDN00000000 and intergenic spacer sequence FM180556) were all located in the M. bovis cluster. The remaining ISR sequences determined in our study, representing M. spumans and M. canadense, were present within the M. hominis cluster. ![Phylogenetic tree of Mycoplasma intergenic spacer region sequences. Evolutionary analyses were conducted in MEGA X, and the tree was inferred
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Let w(x) be the second derivative of x*3/3 + x. What is w(v(u))? 2u Let c(l) = -4l. Let v(q) = 15q + 2. Calculate v(c(z)). -60z + 2 Let a(i) be the first derivative of 0i + 0i2 - 3 - 1/3i*3. Let g(x) = 2x*2. Calculate g(a(s)). 2s4 Let u = 10 + -8. Let m(z) = 0 + 0 + zu. Let t(f) = f*2 - f - 1. Let o(l) = l + 1. Let k(n) = 3o(n) + 3t(n). Determine k(m(g)). 3g*4 Let m(i) = -63i - 4. Let k(g) = 2g. Calculate m(k(r)). -126r - 4 Let d(x) be the first derivative of -8xJanus TiXY Monolayers with Tunable Berry Curvature. Up to now, two-dimensional (2D) materials with both valley polarization and the Rashba effect are still rare. In this work, a new kind of Janus monolayers TiXY (X ≠ Y, X/Y = Cl, Br, I) is demonstrated to have physical properties of benefit for spintronics and valleytronics. In particular, Janus TiBrI shows Zeeman-type spin splitting of 70 meV, large Berry curvature of 106.22 bohr2, and, at the same time, a large Rashba parameter of 147.95 meV Å. On the basis of k·p perturbation theory, we proposed that the Berry curvature can be adjusted by changing the lattice parameter, which will greatly improve the transverse velocities of carriers and promote the efficiency of the valley Hall device. Biaxial strain from -2.5 to 2.5% was applied on Janus TiBrI to verify the theory mentioned above, and a general relationship between the Berry curvature and lattice constant was obtained.Antileukotoxin antibody produced in the bovine lung after aerosol exposure to viable Pasteurella haemolytica. Experiments were performed to determine the in vivo immunogenicity of Pasteurella haemolytica leukotoxin. Calves were exposed twice to aerosol mists of viable P haemolytica, using a treatment regimen previously shown to induce a resistant state. Pulmonary lavage fluids and serum samples from these calves were assayed for leukotoxin-neutralizing antibodies. Before aerosol exposure, neutralizing antibody titers were routinely found in serum samples, but were not detectable in pulmonary lavage concentrates before exposure. After aerosol exposure, titers of toxin-neutralizing immunoglobulin (Ig)A and IgG antibodies were found in pulmonary lavage concentrates and were accompanied by increased serum toxin neutralization titers.Bluemindo Ergonomic and modern music player designed for audiophiles Bluemindo's user interface consists of a main view of all your digitized album discs, which is searchable and filterable. The playback mode is gapless and support ReplayGain (it can also automatically choose to switch between Album and Track modes, depending on the kind of music that's being played). Last but not least, it brings playlist (automatic and user-made), MPRIS/MediaPlayer2 support and lyrics/artwork downloading. It's a free software distributed under GPLv3 terms and written in Python 3.x using GSTreamer 1.x and GTK 3.x.1. Introduction {#sec1} =============== The face of the HIV/AIDS epidemic has changed dramatically since its emergence in the 1980s. Far from its origins as an illness of homosexual men, HIV/AIDS is increasingly affecting women around the world: in 2008, women made up nearly half of the global population of those infected with HIV (15.7 million women, 33.4 million total) \[[@B1]\]. While spread of the epidemic has slowed, addressing the health needs of women infected with HIV remains an important priority. Recent efforts have largely focused on expanding access to HIV diagnosis and counseling, as well as treatment with highly-active antiretroviral therapy (HAART). Providing reproductive health services to women living with HIV is crucial to improving their overall health. Preventing unplanned or mistimed pregnancy allows a woman with HIV to optimize her own health and has the potential to decrease maternal-to-child transmission of HIV. The World Health Organization (WHO) reports that approximately 90% of children living with HIV acquired the infection perinatally---during pregnancy, birth, or breastfeeding \[[@B1]\]. In a model comparing interventions to decrease maternal-to-child transmission (MTCT) of HIV, increasing use of contraception was found to prevent 28.6% more HIV-positive births than increasing use of peripartum nevirapine \[[@B2]\]. Effective contraception thus offers great opportunity to slow the spread of perinatally acquired HIV, though sexual transmission of HIV may still occur between serodiscordant couples. As access to both modern methods of contraception and antiretroviral drugs (ARVs) expands, women with HIV enter the largely uncharted territory of potential drug interactions. In this paper we will summarize the available literature regarding coadministration of ARVs and hormonal contraception, with a focus on whether ARVs lead to alterations in hormonal contraceptive efficacy. Modern hormonal birth control methods available in the United States include daily pills (combined oral contraceptives (COCs) that contain estrogen and a progestin, as well as progestin-only pills (POPs)), a weekly combined hormonal patch, a monthly combined hormonal vaginal ring, injectable depot medroxyprogesterone acetate (DMPA) given every three months, a three-year etonogestrel (progestin) implantable rod, and a five-year levonorgestrel intrauterine system (LNG-IUS). The latter two are often described as long-acting reversible contraceptives (LARCs). All of these methods are highly effective at preventing pregnancy, with the typical-use failure rate ranging from 0.1% (LNG-IUS) to 8% (POPs, COCs, ring) \[[@B3]\]. Hormonal emergency contraceptives (ECs) are also available, which reduce the risk of pregnancy by 89% when taken within 72 hours of unprotected sex \[[@B3]\]. Contraceptive hormones are metabolized by the hepatic cytochrome (CYP) P450 pathway, which is also responsible for the metabolism of many ARVs \[[@B4]\]. Orally administered contraceptive hormones are subject to extensive first-pass gut and hepatic metabolism, which necessitates higher estrogen and progestin doses than those required when these hormones are given via routes that lead to minimal first-pass metabolism \[[@B5]\]. Whether novel delivery systems (i.e., transdermal or transvaginal) affect the pharmacokinetics of contraceptive hormones, and how these drugs will interact with ARVs, remains unclear. It is also uncertain how LARC methods interact with HAART regimens. Contraceptive steroids mainly work by negative feedback inhibition of the hypothalamic-pituitary-ovarian (HPO) axis, with additional effects on cervical mucus and the endometrium. Exogenous estrogen and progestin both profoundly suppress pulsatile secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) \[[@B6], [@B7]\]. However, most of the contraceptive effects (i.e., ovulation suppression, thinning of the endometrium, and cervical mucus thickening) are due primarily to progestin and are dose-dependent \[[@B6], [@B8]\]. Ethinyl estradiol (EE), the estrogenic component of most currently marketed COCs, is primarily metabolized through the hepatic CYP pathway. Specifically, hydroxylation of EE is catalyzed by the hepatic enzymes CYP3A4 and CYP2C9. Wide variation in the levels of these enzymes among individuals is thought to contribute significantly to large intersubject variability of EE pharmacokinetics \[[@B9]\]. The contraceptive progestins available today also vary widely in their metabolism and pharmacokinetics, with large intersubject and intrasubject variability \[[@B10]\]. Modern management of HIV typically involves a combination of ARVs, commonly described as highly active antiretroviral therapy (HAART), since monotherapy can lead to the development of viral resistance to drug therapy. In treatment-naïve patients, a starting regimen typically includes two nucleoside reverse transcriptase inhibitors (NRTIs) and a protease inhibitor (PI), two NRTIs and a nonnucleoside reverse transcriptase inhibitor (NNRTI), or three NRTIs \[[@B11]\]. [Table 1](#tab1){ref-type="table"} lists the five preferred regimens described by the Department of Health and Human Services (DHHS). Ritonavir, a protease inhibitor, is rarely used for its own antiretroviral activity, but is used for its inhibitory effect on CYP3A4, the liver enzyme that normally metabolizes protease inhibitors. A low dose of ritonavir is used to enhance, or "boost," other protease inhibitors, thereby improving ARV efficacy. This paper will examine the available evidence regarding drug interactions between ARVs and all types of hormonal contraception (HC), including transdermal and transvaginal routes as well as LARC options. Pertinent pharmacokinetic (PK) parameters, such as the maximum serum concentration (C*~max�
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1160, 247, 13406, 1127, 27, 187, 187, 31, 380, 26536, 273, 253, 4804, 275, 9178, 369, 326, 760, 9183, 326, 11392, 247, 35525, 1533, 1374, 285, 1175, 1894, 651, 6351, 776, 1329, 15, 11056, 13, 247, 7431, 3692, 1533, 1374, 310, 37819, 285, 3692, 7122, 310, 521, 22115, 3254 ]	leader who would bring Christian values to the Oval Office because he simply didn't understand them and quite often seemed to be selling the idea that he was faithful the way he might sell Trump Steaks. When speaking at Liberty University just weeks prior to the Iowa Caucus, Trump's salesmanship as a Christian was on full display. At that speech to an assemblage of Liberty University students, who were required to attend, he read from his notes, including a Bible verse from 2 Corinthians 3:17, "Now the Lord is that Spirit: and where the Spirit of the Lord is, there is Liberty." But in what many took as a lack of familiarity with basic Christian parlance, Trump read the book and chapter as "Two Corinthians" instead of the more common "Second Corinthians." Honestly, it was probably just a simple mistake that anyone could have made when reading from notes that had been written by someone else (the notes had been provided by evangelical Tony Perkins, president of the Family Research Council). However, because Trump was already perceived to be falsely selling himself as a fellow Christian just to win the election, the moment seemed like an apt example of his shallow faith. To be clear, questioning the truth of another person's faith is not an action Christians should usually or casually undertake. However, it is also true that one must be vigilant against deception. It does seem worth noting that, regardless of the health of his private relationship with God, Trump's devotion to understanding the tenets of faith appeared Cliff Notes–level at best. Trump's repeated claims that he'd been a church-going Protestant his entire life painted a picture of someone who may very well have clocked in and out of "God time" but also someone who had little genuine interest or curiosity to learn much more than could be picked up by reading a Wikipedia page. Even non-Christians who have been around Christians know some of the basics. It appeared this wasn't true of Trump. When it comes to Christianity, Trump knows the notes but not the tune. When Trump was asked if he'd ever entreated God's forgiveness, the surrounding crowd laughed at the question. They knew it directly challenged Trump's public image as a man who never admitted he was wrong. Trump said, "I'm not sure I have." He went on, "When we go in church and when I drink my little wine . . . and have my little cracker, I guess that's a form of asking for forgiveness, and I do that as often as possible because I feel cleansed." His words exposed his ignorance of both the solemnity of the ritual and its actual theological meaning as an expression of Christ's ultimate sacrifice. What remains depressingly fascinating about Trump is how concerns over his lack of familiarity with or his authenticity on Christian issues are often best illustrated in the way he rejects those very concerns. For instance, after Pope Francis was quoted as saying, "A person who thinks only about building walls, wherever they may be, and not building bridges, is not Christian," most outlets reasonably concluded that he was making reference to Trump's campaign centerpiece: a wall at America's southern border with Mexico. Trump evidently concurred that it was directed at him, and he hit back, saying to a crowd of supporters in South Carolina, "No leader, especially a religious leader, has the right to question another man's religion or faith." Yet, at CNN, they compiled a full history of Trump's calling Barack Obama's faith into question, including saying of Obama's birth certificate, "He may have one, but there's something on that, maybe religion, maybe it says he is a Muslim," as well as tweeting in 2012, "Does Madonna know something we all don't about Barack? At a concert she said 'we have a black Muslim in the White House.'" That same year he also tweeted an article from the conspiratorial website World Net Daily, suggesting a ring President Obama was wearing indicated some sort of Arab origin, saying, "Why does Barack Obama's ring have an [A]rabic inscription," and, after linking the article, adding, "Who is this guy?" It was precisely this type of easily identifiable and seemingly shameless false statements and hypocrisy that continued to make support for him a point of confusion among dissenting evangelicals. But also, sadly, it was a feature that attracted others. As I said earlier, for Christians like myself and some of those quoted here, it was hard to imagine how evangelicals could get truly excited for Trump . . . unless we were simply wrong about what broadly appealed to evangelicals. Guess what? Despite Trump's shaky start in the Iowa Caucus (Ted Cruz won the caucus as well as the evangelical vote), the subsequent primary contests demonstrated that the real estate magnate knew far more about how to appeal to masses of evangelicals than the more traditional evangelical candidates who "spoke the language." At a rally in Iowa in January 2016, Trump told his audience, "Christianity will have power," if he was elected. "Because if I'm there, you're going to have plenty of power. You don't need anybody else. You're going to have somebody representing you very, very well. Remember that." This appeal to powerlessness proved to be devastatingly consequential. It was powerlessness that people felt in Iowa and South Carolina. It was a sense of disenfranchisement that was motivating folks in Texas and Mississippi. For a great many evangelicals, the word _power_ was exactly what they wanted to hear. The idea of having it, and wielding it, was more than intoxicating. It was a lifeline. And in the end, it's what many absolutely believe Trump as president has given them. ## The Shift Trump's acceptance among evangelicals continued to increase as summer approached and his nomination moved toward inevitability. Dissenting evangelicals like myself were faced not only with the looming reality but with the uncomfortable truth that evangelicals had helped put him there. As _Christianity Today_ reported at the time, "Even before the other candidates left the race, Trump was the most frequent choice of all evangelicals, including frequent attendees. Although the levels of support changed according to frequency of attendance, he was still the most frequently chosen in every breakdown in most states." The summer had arrived and the shift had taken place, but the questions, the important questions, are: What happened that precipitated or enabled that change? What took the evangelical movement from questioning and doubting to Jerry Falwell tweets and religious fervor for secular pragmatism? Again, it's utterly essential to keep in mind that until this shift, the doubters and the uncertainty were public and acceptable. And among Christian groups as a whole, as opposed to specifically evangelicals, the acceptance of Trump as "one of us" or even a worthy secular leader was still very much a debatable prospect. In other words, you could still offer dissent or rejection of Trump without being branded an apostate. For instance, after Ted Cruz dropped out and Trump's nomination became certain, the Catholic organization Catholic Vote said the next day in a release, "We will not endorse Donald Trump for President at this time. As much as we oppose Clinton, Trump remains problematic in too many ways to receive our endorsement. With a suspect record, no clear guiding principles, and a history of unpredictability, all we can do for now is take him at his word and hope for the best." This was the kind of statement I would have expected, and I think a great many observers did expect, from most Christian groups. Broadly, it was present and a problem for the campaign. Trump's need to gather support from protestant evangelicals, Catholics, and values voters of all stripes had become increasingly important as the transition to the general election began. This was when he needed the big shift that, we now know, he was able to create. Prior to the summer of 2016, it was by no means assured, or at least was not apparent. In an effort to secure that critical support, candidate Trump held a private meeting with a thousand value-centric conservative leaders in June. Jerry Falwell Jr., whose endorsement in January 2016 had helped identify him as one of Trump's more enthusiastic evangelical surrogates, had this to say: "If we all wait for the perfect candidate who has the demeanor of our pastors and agrees with us on every issue, including our personal theological beliefs, then we may all sit at home on election day for the rest of our lives. How many of you can honestly say that you even agree with your spouse on everything?" That was the frame, and that meeting was when the evangelical attitude toward Trump transitioned from "peculiar to a subset of Christian voters" to "the way things are." The importance of the meeting was lost on no one. Penny Nance clarified the purpose and significance, saying of Trump, "He needs to win our hearts." Evangelical figure Michael Farris, chairman of the Home School Legal Defense Association, who was not invited to the meeting, offered a very pessimistic view. He had been specifically told by one of the meeting's organizers that he was not invited because he'd been too "anti-Trump" up to that point. On the day of the event, Farris had an op-ed in the _Christian Post_ in which he referenced his participation long ago at the very first meeting of Falwell Sr.'s Moral Majority back in 1980. He made a remarkable point: > The premise of the meeting in 1980 was that only candidates that reflected a biblical worldview and good character would gain our support. Today, a candidate whose worldview is greed and whose god is his appetites
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2783, 281, 320, 253, 40652, 273, 7496, 272, 253, 9459, 15, 31466, 254, 27, 1422, 753, 27, 773, 9586, 604, 309, 717, 11407, 668, 1108, 309, 457, 69, 751, 281, 1333, 326, 352, 310, 16656, 336, 26430, 544, 3529, 436, 651, 5108, 281, 368, 1570, 831, 6197, 310, 247, 2372, 36074, 2866, 47420, 26153, 9720, 27, 309, 753, 27, 773, 9586, 604, 1425, 31466, 254, 27, 309, 6983, 326, 1580, 253, 5068, 273, 253, 15033, 13, 690, 273, 253, 1270, 952, 275, 436, 9459, 2866, 2726, 616, 1211, 3564, 2866, 3808, 952, 452, 11407, 616, 1211, 2151, 15, 6279, 15, 1583, 14048, 616, 1211, 2151, 689, 281, 253, 14954, 13487, 1108, 436, 310, 14331, 2, 47420, 26153, 9720, 27, 1707, 497, 14431, 3692, 2151, 497, 1146, 11407, 323, 18327, 253, 9459, 13, 285 ]	immobilizera immobilizer NOUN subst:sg:gen:m3 Animacy=Inan\|Case=Gen\|Gender=Masc\|Number=Sing 1 nmod _ _ 3 to to AUX pred _ 4 cop _ _ 4 wydatek wydatek NOUN subst:sg:nom:m3 Animacy=Inan\|Case=Nom\|Gender=Masc\|Number=Sing 0 root _ _ 5 około około PART qub _ 7 nmod _ _ 6 kilkuset kilkaset DET num:pl:gen:m2:congr Animacy=Nhum\|Case=Gen\|Gender=Masc\|Number=Plur\|NumType=Card\|PronType=Ind 7 det:nummod _ _ 7 złotych złoty NOUN subst:pl:gen:m2 Animacy=Nhum\|Case=Gen\|Gender=Masc\|Number=Plur 4 nmod _ SpaceAfter=No 8 . . PUNCT interp _ 4 punct _ _ ~~~ ~~~ conllu # visual-style 22 bgColor:blue # visual-style 22 fgColor:white # visual-style 18 bgColor:blue # visual-style 18 fgColor:white # visual-style 18 22 det:nummod color:blue 1 Sprytny sprytny ADJ adj:sg:nom:m1:pos Animacy=Hum\|Case=Nom\|Degree=Pos\|Gender=Masc\|Number=Sing 2 amod _ _ 2 oszust oszust NOUN subst:sg:nom:m1 Animacy=Hum\|Case=Nom\|Gender=Masc\|Number=Sing 4 nsubj _ _ 3 jest być AUX fin:sg:ter:imperf Aspect=Imp\|Mood=Ind\|Number=Sing\|Person=3\|Tense=Pres\|VerbForm=Fin 4 cop _ _ 4 przekonujący przekonujący ADJ adj:sg:nom:m1:pos Animacy=Hum\|Case=Nom\|Degree=Pos\|Gender=Masc\|Number=Sing 0 root _ SpaceAfter=No 5 , , PUNCT interp _ 8 punct _ _ 6 swym swój DET adj:pl:dat:f:pos Case=Dat\|Gender=Fem\|Number=Plur\|Poss=Yes\|PronType=Prs\|Reflex=Yes 7 det _ _ 7 ofiarom ofiara NOUN subst:pl:dat:f Case=Dat\|Gender=Fem\|Number=Plur 8 iobj _ _ 8 proponuje proponować VERB fin:sg:ter:imperf Aspect=Imp\|Mood=Ind\|Number=Sing\|Person=3\|Tense=Pres\|VerbForm=Fin 4 conj _ _ 9 pozostawienie pozostawienie NOUN ger:sg:acc:n:perf:aff Aspect=Perf\|Case=Acc\|Gender=Neut\|Number=Sing\|Polarity=Pos\|VerbForm=Vnoun 8 obj _ _ 10 obrączki obrączka NOUN subst:sg:gen:f Case=Gen\|Gender=Fem\|Number=Sing 9 obj _ _ 11 lub lub CCONJ conj _ 14 cc _ _ 12 innej inny ADJ adj:sg:gen:f:pos Case=Gen\|Degree=Pos\|Gender=Fem\|Number=Sing 14 amod _ _ 13 bezwartościowej bezwartościowy ADJ adj:sg:gen:f:pos Case=Gen\|Degree=Pos\|Gender=Fem\|Number=Sing 14 amod _ _ 14 rzeczy rzecz NOUN subst:sg:gen:f Case=Gen\|Gender=Fem\|Number=Sing 10 conj _ _ 15 w w ADP prep:acc:nwok AdpType=Prep\|Case=Acc\|Variant=Short 16 case _ _ 16 zastaw zastaw NOUN subst:sg:acc:m3 Animacy=Inan\|Case=Acc\|Gender=Masc\|Number=Sing 9 nmod _ _ 17 i i CCONJ conj _ 18 cc _ _ 18 zwrot zwrot NOUN subst:sg:acc:m3 Animacy=Inan\|Case=Acc\|Gender=Masc\|Number=Sing 9 conj _ _ 19 gotówki gotówka NOUN subst:sg:gen:f Case=Gen\|Gender=Fem\|Number=Sing 18 nmod _ _ 20 za za ADP prep:acc AdpType=Prep\|Case=Acc 22 case _ _ 21 kilkadziesiąt kilkadziesiąt DET num:pl:acc:f:rec Case=Acc\|Gender=Fem\|Number=Plur\|NumType=Card\|PronType=Ind 22 det:numgov _ _ 22 minut minuta NOUN subst:pl:gen:f Case=Gen\|Gender=Fem\|Number=Plur 18 det:nummod _ SpaceAfter=No 23 . . PUNCT interp _ 4 punct _ _ ~~~ The inhumanity of this is staggering. The evil of it is off the charts. This is the regime that Barack Hussein Obama empowered and enabled and showered billions of dollars upon. This is the regime that the Democrats are intent upon propping up. There are courageous Iranians now who are increasingly open about their opposition to the brutal and bloody mullahs, and they deserve all the support we can possibly give them. The idea that any country in the world would respond to this regime and all of its institutionalized savagery with anything but contempt and revulsion is breathtaking. “IRGC Strategist Hassan Abbasi Praises Iranians Who Handed Over Their Own Children for Execution for Opposing the Regime, Says: 2,300 Iranians Were Killed in Syria War,” MEMRI, February 6, 2019: IRGC strategist Hassan Abbasi said in a February 6, 2019 interview on Ofogh TV (Iran) that guarding the Islamic Republic is a top priority, even if he disagrees with some of the laws or if the law would require him to be sentenced to death. Abbasi and the interviewer praised people who handed their own children over to be executed for opposing the Iranian regime. Abbasi also said that Iran’s pinnacle of achievement is raising and educating valiant young men to the level that they are willing to martyr themselves for the regime. Following are excerpts: Hassan Abbasi: I have been jailed in the Islamic Republic several times, but we consider the guarding of the Islamic Republic to be our top duty. The Islamic Republic has laws. Even if you and I do not agree with the law, we still must follow it. Even if, according to the laws of the Islamic Republic – laws that we might consider to be defective or limiting… Even if, according to the law, someone like me is sentenced to death… [Even if this were to happen,] as far as I am concerned, guarding the Islamic Republic is my top-most duty. Guarding the regime of the Islamic Republic, guarding the legislative branch, guarding the executive branch, guarding the judicial branch, guarding the different bodies, the public, the country, its territorial integrity… All these things are considered to be the pillars of guarding the regime. Interviewer: You said: “Even if I am executed” – I’d like to say that it is inconceivable [that this would happen to you]. This sentence is a bit exaggerated… Hassan Abbasi: I said: “Even if.” Interviewer: I recall that since the beginning of the Revolution, some of the great people in this regime… With their own hands… Some people have executed their own children. Yes. They handed their own children over to the firing squad – this is incredible! Hassan Abbasi: There were mothers whose children were being executed for opposing the regime, and
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10246, 770, 187, 1738, 187, 4387, 966, 16275, 2135, 23088, 5089, 17930, 16275, 2135, 9294, 29, 2776, 31, 551, 535, 50274, 6930, 187, 50273, 11, 5595, 5044, 1083, 835, 28267, 1332, 10224, 285, 253, 2965, 2135, 6548, 247, 906, 313, 2369, 1332, 7125, 10, 187, 50273, 8480, 187, 50274, 33, 5089, 187, 50274, 4387, 2991, 2965, 2135, 6942, 9, 2387, 12326, 19563, 551, 187, 50270 ]	angoon told The Irrawaddy the case of a 7-year-old girl, who was brought to her clinic by her mother after an extended period of vaginal bleeding. The mother thought she had begun menstruating, but the checkup revealed the girl had been raped. “But the mother could not believe it,” she said, adding that parents often did not want to accept their children had been subjected to such a heinous crime. Meanwhile, those subject to attacks suffer from lifelong trauma, chronic health problems, and in the worst cases, die from their injuries. Not Safe with Neighbors It remains customary for ordinary mothers and fathers in Burma to trust their neighbors with the care of their children, particularly in rural areas where older members of the community need to work the land. Yet in almost all cases of child sex abuse, particularly those widely reported on in recent months, neighbors are the alleged perpetrators. Reported cases of immediate family members abusing their young siblings or children are also on the rise. In two separate cases in Moulmein, a girl under the age of four and a five-year-old girl were sexually assaulted by their neighbors. Both perpetrators came before the same judge. Both men were immediately granted bail. In one harrowing instance, a 14-year-old girl was abducted from her home in Mon State’s Kyauktan village and taken to a house in the border town of Myawaddy, where she was shackled and raped repeatedly over four days. Her kidnapper remains at large despite her rescue. In October and November, the rape of two girls aged four and eight in separate cases sparked an outburst of public anger in Sittwe. One of the perpetrators was serving as a soldier in the Burma Army, while the other had recently deserted. Both victims died from their injuries. The perpetrator in one case was quickly handed over to a military tribunal, which quickly sentenced him to 12 months in prison. Following a riotous protest outside Sittwe’s central police station, the accused is now before a civilian court. Khin Than Htwe, a community worker in Moulmein, told The Irrawaddy the case of a young girl repeatedly raped by her older brothers in Mon State’s Nyaung Gone village, who were sentenced to only five months’ imprisonment. “There is no protection for her. She had to live with her brothers again after that,” she said. Law Favors Culprits Sexual abuse of young children are the most common rape cases, according to police records published in local media. In Burma, children under 14 are afforded a wide range of legal protections under the Child Law, but there are little or no legal protections for children vulnerable to abuse. Aye Nu Sein, a Sittwe-based lawyer and vice-chair of the Arakan National Party (ANP), pointed out that there is no difference in charges or sentencing between those rapists who attack adults and those who sexually abuse children. A handful of lawyers, politicians and activists have called for legal reform to increase sentences for those who engage in child sexual abuse, but so far, attempts to legislate harsher punishments for perpetrators have failed. Part of the reason for the deadlock could be attributed to the demands of the more strident campaigners, including a concerted push to mandate the death penalty, a demand from which incumbent lawmakers have quietly recoiled. Outgoing lawmaker Thein Nyunt of the New National Democracy Party has spent years campaigning for an increase in prison sentences and the imposition of capital punishment for child sex abusers, a view he reiterated to The Irrawaddy. “There have been many things we have done to prevent sexual assault of children, but cases have increased,” he claimed. “We must prevent it by trying to put fear in the perpetrators. Therefore capital punishment should be imposed. One punishment could prevent at least 20,000 children from being sexually assaulted.” Thein Nyunt’s views appear to be gaining traction. Kyaut Sein, a social activist helping the families of the victims in Sittwe, is outraged at the lenient sentence handed recently handed down by the military court. Echoing widespread sentiment in the town, she agreed that perpetrators guilty of child sexual abuse should be subjected to capital punishment. “The death penalty should be given to those rapists, to prevent further rapes against the children,” she said. Lawyer Robert San Aung, noted for his involvement as defense counsel in a number of high profile human rights cases, agreed that execution was a just punishment for the crime, citing the need for a strong deterrent to protect Burma’s “stability”. “As cases of rape against young children are on the increase, harsh punishment is desperately needed,” he told The Irrawaddy. “It seems we have to accept capital punishment. The more the increase in the child sexual assault, the more it will impact on the stability of the country.” Others, while conceding the need for stronger punishments, stopped short of supporting mandatory capital punishment, saying that more focus was needed on prevention mechanisms and awareness. “The death penalty is a strong word, said Htoot May, an ANP member recently elected to an Upper House seat in Arakan State. “We need to protect our children, and we need stronger laws to do that.” Khin Oo Tha contributed to this report.Sources: Wrigley Renovation Deal Could Be Done By Home Opener Sources: Wrigley Renovation Deal Could Be Done By Home Opener The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports. The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports. The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports.sleep 1 t cal -de 4 /* * DO NOT ALTER OR REMOVE COPYRIGHT NOTICES OR THIS HEADER. * * Copyright (c) 2019-2020 Payara Foundation and/or its affiliates. All rights reserved. * * The contents of this file are subject to the terms of either the GNU * General Public License Version 2 only ("GPL") or the Common Development * and Distribution License("CDDL") (collectively, the "License"). You * may not use this file except in compliance with the License. You can * obtain a copy of the License at * https://github.com/payara/Payara/blob/master/LICENSE.txt * See the License for the specific * language governing permissions and limitations under the License. * * When distributing the software, include this License Header Notice in each * file and include the License file at glassfish/legal/LICENSE.txt. * * GPL Classpath Exception: * The Payara Foundation designates this particular file as subject to the "Classpath" * exception as provided by the Payara Foundation in the GPL Version 2 section of the License * file that accompanied this code. * * Modifications: * If applicable, add the following below the License Header, with the fields * enclosed by brackets [] replaced by your own identifying information: * "Portions Copyright [year] [name of copyright owner]" * * Contributor(s): * If you wish your version of this file to be governed by only the CDDL or * only the GPL Version 2, indicate your decision by adding "[Contributor] * elects to include this software in this distribution under the [CDDL or GPL * Version 2] license." If you don't indicate a single choice of license, a * recipient has the option to distribute your version of this file under * either the CDDL, the GPL Version 2 or to extend the choice of license to * its licensees as provided above. However, if you add GPL Version 2 code * and therefore, elected the GPL Version 2 license, then the option applies * only if the new code is made subject to such option by the copyright * holder. / package fish.payara.microprofile.faulttolerance.policy; import static org.junit.Assert.assertEquals; import java.lang.reflect.Method; import org.eclipse.microprofile.faulttolerance.ExecutionContext; import org.eclipse.microprofile.faulttolerance.Fallback; import org.eclipse.microprofile.faulttolerance.FallbackHandler; import org.junit.Test; import fish.payara.microprofile.faulttolerance.service.FaultToleranceServiceStub; import fish.payara.microprofile.faulttolerance.test.TestUtils; /* * Tests the basic correctness of the {@link Fallback} handling. * * @author Jan Bernitt / public class FallbackBasicTest implements FallbackHandler<String> { /* * Most basic case where annotated method fails and the fallback returns a result (no method arguments) */ @Test public void fallbackMethod( ) throws Exception {
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Let r be (-13 + 1-2)t/15. Solve -5x = -4v + r, -5 = -v + 6x - 3x for v. 5 Let p = -4905 + 4907. Solve 2 = d, 2u + p = 5u + d for u. 0 Suppose 4c - 2l - 14 = -2, -2l + 12 = 2c. Suppose 5 = 3v - c. Suppose -6y + v = 3. Solve 4s - 20 = y, -3s = -f - 0f - 15 for f. 0 Let b be (-1)/31 - 10/(-3). Suppose -bt - y = 1, 3y + 4 = 4t - y. Let z be (11 - 6) + (-2 + 2 - 1). Solve -zx + t - 12 = 0, -l = -x for l. -3 Let q = 6084 - 6081. Solve c - q = -17y + 20y, -3c = 9 for y. -2 Let l(u) = u2 - 22u - 73. Let t be l(25). Suppose -5 = -tf + 3, 0 = -3v + 4f - 1. Solve 4w - 4r + 2 = -10, 0 = vw + 5r - 15 for w. 0 Let h(a) be the first derivative of 12a - 10 + 9a - 4a - 3a + 2a*2. Let d be h(0). Solve 0 = 4s - 5c + 22, 0s + 4c = 2s + d for s. -3 Let v be ((-4)/9)/(9 - 166/18). Solve 5a + 0a - vg + 30 = 0, -g + 13 = -2a for a. -4 Let q = -1 + -1. Let l be (4 + (12 - -1))(q + 5). Let u = l - 49. Solve -4w - 18 = 5d, 3w = ud + 1 - 3 for w. -2 Let m(u) = -14u + 7. Let r(a) = -12a + 6. Let s(h) = 5m(h) - 6r(h). Let d be s(2). Solve -dg + 8 = -k - k, -k = g - 6 for g. 4 Suppose 2y + 24 = 4a - 2y, -6 = -5a - 3y. Solve i + i - 17 = ag, -4i + 4 = 0 for g. -5 Let z(h) = 518h + 3629. Let g be z(-7). Solve -gy - 93 + 112 = -2s, y = 3 for s. -5 Suppose 0 = 4i + 4n - 2n + 22, -2i - 3n - 21 = 0. Let p be 4 - (4 - (3 + i)). Suppose 0 = -pm + m. Solve -3l + 3c = m, 5l = -2c - 5 - 2 for l. -1 Let s(v) = -5v - 20. Let a be s(-4). Suppose 5n + 3t + t = a, 3t = 0. Solve -3f - 12 = -4l - nl, 3l - 8 = 2f for f. -4 Suppose 0 = 22y - 101 - 119. Suppose -yv + 4 = -56. Solve 2w - 8 = 0, w - 19 = vk - k for k. -3 Suppose -7l - 3l + 400 = 0. Let m be (-4)/(l/25)-6. Solve 0 = -5b + 5f - m, -b + 5f + 9 = 24 for b. 0 Let l(c) = -7c*2 - 282c - 78. Let p be l(-40). Solve -4n = -2t - p, -7t + 0n = 3n - 44 for t. 5 Let y be (2-1)/(-2) - -21. Suppose 3o = -25 + 88. Suppose -3k - 3i + o = 0, -4k + 24 = -k + 4i. Solve -kx + 2 = -5x, y = -4n - 3x for n. -4 Let y = 28 + -17. Let x be ((-1)/3)/((-29)/435). Suppose xu - 48 = -u. Solve -2z = -3n - y, z + 2n = 3 - u for z. 1 Let j(s) = -s3 - 6s*2 - 6s. Let k(r) = -6r - 30. Let n be k(15). Let u = n + 115. Let w be j(u). Solve 0x - x - wg = -7, 4x = 5g - 22 for x. -3 Suppose -8 = -3z + 4z. Let d be (-10)/z - 2/((-16)/6). Suppose 0 = -u - 2t - 8, 3u - 26 = -t + 5t. Solve -dn - 3c = 1, -3c = -n + 2 + u for n. 1 Suppose 0 = 4y + 21 + 59. Let q be ((-22)/(-4))/(y/(-40)). Solve qu - 6u - 5 = 5b, 3u - 11 = b for b. 4 Let v(g) = 47g2 - 41g + 26. Let l be v(1). Solve 30f - lf - 2m - 16 = 0, -4f = -m + 7 for f. -3 Let y be (-1)/(-2 + 10/6). Suppose 2k - k - 4 = 0. Let w be 20/55121/22. Solve -y = -kv - q - 2q, -4v + w = 2q for v. 0 Let o be -2 + 63/13 + 26/169. Let z(a) = -a*3 + 2a*2 + 5a - 4. Let b be z(o). Solve -3x + 25 = -g + 6g, bg = -x + 10 for x. 0 Suppose 0 = l - 5m - 25, -3l - 42m = -36m + 30. Solve 3f - 4g + 44 - 58 = l, f - 18 = 4g for f. -2 Suppose 2u + 25 = -5g + 208, -3g - u + 109 = 0. Let v(f) = -f3 + 35f*2 + 40. Let i be v(g). Solve -5j - i = -0j - 5m, 3 = -3j - 4m for j. -5 Suppose 9p - 71 = 64. Let w = -5 - -9. Suppose -3f - f = -3y - 17, -wf + 5y = -p. Solve 22 = 2o - 3m + 7, 0 = fo + 2m + 10 for o. 0 Let d = -272 - -283. Let f(k) = k2 - 15k + 44. Let z be f(d). Solve 5 = -g - a, g + 2a + 2a + 17 = z for g. -1 Let i = -167 + 169. Suppose 0 = 2k - ia + 2, 12 = 5k + 2a - 11. Solve u + 12 = -kb, u - 4b = -3b + 8 for u. 3 Let l(g) = -g - 16. Let d be l(-18). Let t be 1(-3 + d) + 2. Suppose 4z = 3z + t. Solve h = 2j - 2h + z, -4j + 2h - 6 = 0 for j. -2 Let i(r) = r*2 + 7r - 44. Let u be i(4). Suppose 4c - w - 3w - 32 = 0, c - 5w = u. Solve -3x + 5b + c = 4b,
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5312, 49681, 281, 253, 2846, 323, 16610, 789, 428, 247, 3946, 326, 556, 8228, 275, 6349, 281, 253, 3114, 15, 50276, 29764, 555, 3972, 7390, 14, 46, 1911, 1004, 330, 710, 497, 11217, 275, 16648, 15, 50276, 688, 253, 3563, 10333, 84, 1980, 7756, 5659, 3977, 281, 247, 3585, 1562, 1320, 273, 253, 1980, 3114, 407, 8362, 7466, 285, 4980, 1320, 273, 253, 6773, 4444, 285, 253, 12692, 273, 1824, 285 ]	was alone when he was shot. Neighbor Jean Petry saw Pace’s mother and sister trying to comfort him before the paramedics arrived. “For a 16-year-old boy to be shot — I just can’t imagine,” Petry said. “It could have been one of my own.” Pace was taken to UPMC Mercy Hospital in critical condition where he was pronounced dead. Police have not yet established a motive. “Apparently, there were two if not three blacks males that approached him and one of them pulled a gun out and fired at least three shots at him,” Lt. Hermann added.Petty Harbour–Maddox Cove Petty Harbour–Maddox Cove is a town of approximately 960 people located on the eastern shore of the Avalon Peninsula in the province of Newfoundland and Labrador, Canada. It is nestled deep in the heart of Motion Bay, just south (approximately 15 minutes away) of St. John's. The present town is approximately 200 years old, though the site has been continuously occupied since at least 1598, predating the arrival of the Mayflower and making it one of the oldest European settlements in North America. During King William's War, the village was raided by French forces in the Avalon Peninsula Campaign. Petty Harbour–Maddox Cove is the site of the Petty Harbour Generating Station, the first hydroelectric generating station in Newfoundland and Labrador. It was also the Tidy Towns population category winner for 2007. This award is based on natural beauty, community involvement, environmental awareness and Heritage preservation. Etymology The name "Petty Harbour" is the anglicized form of the French name "Petite Havre" meaning Small Harbour. History By 1500 "Pettite Harbour" was probably already a regular seasonal base for the Basque fishery, and by the 1600s the English had taken it over. Richard Whitbourne records a decisive "set-to" between English, who were probably royally licensed privateers, and Portuguese at "Petyte Harbour" in 1619. An excellent base for pirates, Petty Harbour afforded a good hiding place for their small ships, intent on attacking vessels approaching St. John's (as late as 1791 two Yankee privateers were captured there). In 1621 control of Petty Harbour was shared by William Vaughan, George Calvert, and the London and Bristol Company, although none of these absentee owners attempted settlement or regulation of the fishery. In 1637 David Kirke's settlement brought by-boat keepers (landowners who hired fishing servants) to Petty Harbour, and this practice continued after the settlement attempt failed. The anglicized spelling of the place name was soon established - in his 1604 Journal, James Yonge records a journey overland from St John's to "Petty Harbour” to “look after our men". From this period until the nineteenth century, the economy of the area was dominated by "Newman and Company”, a West Country firm, which owned and rented out most of the land and controlled trade. From 1664 to 1850 the Newman and company, and English West Country owns most of the lands and controls the trade in the fishery. Though the migratory fishing interests discouraged settlement, “Berry’s List" of 1675 records 5 planters 3 wives, 1 child, 39 servants, 10 boats, 4 stages, 3 vats and 6 cattle. Early settlement was, however, subject to difficulty and danger. From 1676 to 1678 migrant fishermen seasonally razed settlers' houses and premises. The presence of this settled fishery so close to St. John's was a red flag to migratory fishermen anxious to protect their privilege of "freedom of fishing" and in 1676 and 1678 rooms at Petty Harbour were destroyed by crews of fishing ships. In 1696 Petty Harbour was attacked and destroyed by the French. Lemoyne D'Iberville met his first resistance from 30 fishermen from Petty Harbour, who retreated behind the Petty Harbour River to a trench they had constructed. The fishermen were quickly overwhelmed by the soldiers, but managed to inform St. John's of the invasion. Two days later a force of 80 men sent out from the capital were also handily defeated by the French. Some 36 fishermen were killed in the battle and others were taken prisoner. When the French confronted the small winter garrison at St. John's, they scalped one prisoner, William Drew, to strike terror into the hearts of the St. John's men and the capital surrendered. Daniel d'Auger de Subercase assembled a group of raiders composed of Mi'Kmaq and Canadians from Québec to help in the campaigns against British settlements. They captured Bay Bulls and Petty Harbour in January 1705 and then marched on St. John's. In 1789 the brig Duke of Leinster arrived in the night leaving 12 women and 102 boys in Bay Bulls and Petty Harbour. These were Irish convicts whose original destination was Australia, but with high shipping costs, Newfoundland was deemed a more economical place. Increases in crime and typhus in St. John's lead to the deportation of the convicts back to Dublin three months later. In August 1796 a French squadron under Admiral de Richery threatened St. John's and destroyed the settlement of Petty Harbour and Bay Bulls, seriously disrupting the bank fishery. Nevertheless, settlement gradually increased. As the by-boat keepers, who settled the southside due to its favorable winds for drying fish, were mostly English and Protestant, and the Irish, who were forced to settle the north side, were chiefly Roman Catholic, the community was accidentally segregated on sectarian lines from an early time. The 1794-95 census records a population of 255 in 50 households, with 16 "heads of households" Newfoundland-born. There were 133 Protestants and 122 Catholics. Prominent surnames included Angel, Chafe, French, Kennedy, Matthews and Welsh. Most people were occupied in the fishery, and there were two carpenters, two coopers, two laundresses and a surgeon. A Church of England church as built about 1800, and a Roman Catholic church in 1832. By 1857 Petty Harbour's population had risen to 747 (29 of whom were born in Ireland and 22 in England), nearly twice as many Catholics as Protestants. There were two churches, over 100 dwellings, two schools with some 105 pupils, premises for salting fish and three cod oil factories. Education was in the charge of the interdenominational Newfoundland School Society. In addition to the three R's, sewing and knitting were offered for girls and net-making for boys. One of Newfoundland's best known folk songs - the Petty Harbour Bait Skiff was written about Petty Harbour men who drowned in June 1852, while returning from Conception Bay with a load of bait. It was composed soon after the tragedy by John Grace of St. John's, where there was "crying and lamenting in the streets" on learning of the fate of Skipper John French and his crew "all on the eighth of June". Only one of the crew, "young Menshon", was saved by "Jacob Chafe that hero brave." By the 1850s the population (747 inhabitants) had begun to exceed the capacity to support it: shore space and housing sites were taken up, and the wood supply was exhausted. Some residents moved inland to Doyles and the Goulds to supplement their earnings by logging and farming. When it became clear that the growing population could not be sustained even by these measures other people began to move, first to nearby Maddox Cove and then to the arable farmland of the Goulds. While the Goulds formed its own community, Maddox Cove continued its close connection with Petty Harbour. With new room for expansion of the population of Petty Harbour (now usually counted to include Maddox Cove) continued to grow, reaching 1053 in 1891. This increase in population can be partly attributed to a new wave of Irish immigrants who settled in Maddox Cove. Prominent surnames in Maddox Cove included Chandler, Drake, Hanniford, Healey, Heffernan, Madden & O'Brien. At this time 60% of the residents were Roman Catholic, 30% Church of England and 10% Presbyterian; and 250 students attended four schools. The turn of the century saw changes in the community's economy and character. In 1898 the Reid Newfoundland Company built Petty Harbour Generating Station Newfoundland's first hydro-electric generating station. It began operation on April 19th 1900, delivering power for St. John's streetcar system and commercial lighting. This brought alternative employment to the area, as well as relatively cheap electricity, but controlling the water supply created practical difficulties and health problems. At this time, with the Goulds woodlands depleted, the sawmills at Petty Harbour closed. The 1909 rail link between St. John's and Trepassey increased contact with St. John's, and the 1932 road made feasible daily commuting to the city for wage work - a practice that has grown in importance to the community. Petty Harbour-Maddox Cove were incorporated in 1969. In the late 1970s local improvement programs led to a revitalization of the local community by funding expansion and modernization of the fish plant and the installation of water and
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In this paper, we specifically consider predicting traffic congestion at a morning time $t$, using household-level electricity usage data during the time interval $[t',t'']$ that can be up to a few hours earlier than $t$ on the same day. As we will show later, this predictor can outperform a predictor using only the traffic data, even at the time much closer to $t$ than $t''$. This is because morning traffic break-down is largely attributed to random demand characteristics, such as demand level, driving behavior, departure time from home, etc. Those demand characteristics can hardly be predicted using traffic data only in the real time, and oftentimes the traffic break-down may occur in the morning peak without sufficient prior signs from traffic data. Our hope is that electricity use at midnight or in the very early morning can partially reveal those demand characteristics to some extent, and therefore can help better predict traffic congestion for some locations. Consider electricity use data at the household level. On each day, $e^d_h(t)$ denotes the electricity use at time of day $t$ on day $d$ for the $h$-th household. Suppose we collected data for $H$ households, $D$ days, and $T$ time-of-day intervals. $e^d_h\doteq \{e^d_h(t)\}_t$ is a $T\times 1$ vector, also known as a daily profile of electricity use on day $d$ for the $h$-th household. There are in all $DH$ daily profiles. Similarly, $e^d\doteq \{c^d_h\}_h$ is a $TH\times 1$ vector, namely daily observations for electricity use. We intend to predict both “congestion starting time” and “congestion duration” on a road segment, denoted by $k^d$ and $c^d$ on day $d$, where both $k^d$ and $c^d$ are at a much later time than those $T$ time intervals of electricity use observations. Our goal is to establish, $$\label{pred} k^d = f(e^d;\beta), c^d = f'(e^d;\beta')$$ Where $f(\cdot)$ and $f'(\cdot)$ is a model mapping electricity use to congestion starting time and duration, respectively, and $\beta,\beta'$ are a vector of parameters to be learned from data. The intuition behind $f(\cdot)$ and $f'(\cdot)$ is that electricity use from midnight to 5:30am may reveal demand characteristics, namely what time, and how many travelers depart home for work. For instance, electricity use of a household drops when family members go to sleep, or it drop when they depart home. However, due to complicated spatio-temporal relationship among electricity use and transportation system use, $f(\cdot), f'(\cdot)$ are generally unknown and difficult to construct using real-world physics. Therefore, we use data mining models (i.e., regression models) to estimate $\theta,\theta'$ for assumed functions $f(\cdot)$ and $f'(\cdot)$. There are many different ways to construct functions $f(\cdot)$ and $f'(\cdot)$. Complicated data mining models such as Neural Networks can deal with high dimensional data, but can be notoriously difficult to interpret. In order to obtain insights regarding cross-system interrelations, in this paper, we use simple linear predictors in conjunction with an unsupervised learning approach. Clustering ---------- We suppose there exist some typical profiles of the electricity use, namely daily patterns, that characterize individuals and their daily activities. It is expected the influence of each pattern of individuals and their daily profiles to the traffic congestion is stable from day to day, and can be mined using historical data. Some intuitive examples include, - One daily pattern could be that there is a spike of electricity use from midnight to 2am, while the use is low during the morning til 6am. This implies that the group of users under this pattern may not commute during the morning peak, and therefore they tend to not contribute to the congestion. - A second daily pattern could be that electricity use of a user is low from midnight to 5:30am, followed by a rise after 5:30am. This is perhaps a typical “morning commute” pattern for a typical commuter. - Another daily pattern may be that the electricity use steadily declines over time from midnight to 5:30am, as a result of air conditioning running all night during the summer. Then the use rises at 5:30am for commuters’ morning activities. Some daily patterns are straightforward to relate to users’ activities. However, electricity use can be attributed to many other factors that are random, noisy, and hard to interpret. Therefore, we use a data-driven approach to separate observations into “clusters” or “typical patterns” that are representative of typical electricity use among all sampled users. The increase and decline of electricity use over time for all patterns will be determined by the statistical models rather than manual specifications. Another note to make here is that a user can switch among those typical patterns from day to day. A user may be a commuter, namely under a typical commuter daily pattern, from Mondays to Thursdays, while behaving under a non-commuting daily pattern on Fridays. She does not contribute to the morning-peak congestion on Fridays. We would like to use data mining models to capture the characteristics of individuals and their patterns on each day, both of which are used to predict morning congestion. In this paper we use the simple k-means clustering algorithm to learn daily patterns. We have $H$ households and their daily profiles of $D$ days, in all $DH$ samples: $\{e_h^d\}_{d,h}$. We partition the samples into $K$ clusters (or typical patterns) denoted as pattern $1$, pattern $2$, ... , pattern $K$. Each pattern $i$ is represented by the centroid of its cluster (usually the numerical average) $e_i$. The number of clusters $K$ must be predefined before performing the clustering. The GAP statistics ([@tibshirani2001estimating]) can be used to determine the value of $K$. A linear predictor ------------------ We assume that congestion starting time on the $d$-th day is predicted by its expected value that is a linear combination of many features, $$\begin{aligned} \mathbb{E}(k^d) = \beta^T x^d $$ Where $x^d$ is a vector of $p$ features observed on the $d$-th day. $x^d = [x_1^d,x_2^d,...,x_p^d]$. Those features are derived from daily profiles $e^d$. The commonly used ordinary least square (OLS) linear predictor is to learn the parameters $\beta$ such that $$\begin{aligned} \min_{\beta} \|\|k-x^{\top}\beta\|\|_2\end{aligned}$$ However, if the dimension of $x$ becomes very large or larger than the sample size, then the regression tends to overfit the data. To overcome this issue, we use both L1-norm penalization and cross validation. The first idea is to add a L1-norm regularization of $\beta$ (LASSO, [@tibshirani1996regression] ) and the original problem becomes, $$\begin{aligned} \min_{\beta} \|\|k-x^{\top}\beta\|\|_2+\alpha \|\|\beta\|\|_1\label{lasso}\end{aligned}$$ $\|\|\beta\|\|_1 = \sum_i \|\beta_i\|$ denotes the $L1$ norm of $\beta$. The LASSO regression helps select the most critical features that are linearly related to the response. Second, K-fold cross-validation will be used to measure the performance of our model. We construct features on each day that are derived from the clustering results of daily profiles. Note that the k-means algorithms are applied on the $DH$ daily profiles. Thus, each household or user on each day will be assigned to a typical pattern (cluster). Features that are related to traffic congestion can be both aggregate or disaggregate. At an aggregate level, we assume that all households/users under the same typical pattern on each day affect the congestion in the same way (namely all households/users under the same pattern are homogeneous), and speculate that the total number of households/users under each of the typical patterns on each day attributes to congestion. At a disaggregated level, we assume each sampled household/user represents a particular group of users, and each contributes to congestion differently as opposed to the user homogeneity assumption. Therefore, we create features for each sample household/user for the predictor of traffic congestion. In the rest of the paper, we refer to the two types of features as “aggregate features” and “disaggregate features”, respectively. Aggregate features are highly compressed. They are a vector of $K-1$ elements for each daily profile. Each element is the ratio of households/users that are under a pattern on that day. The element of one last pattern can be dropped from the vector as a result of redundancy. Those aggregate features would offer effective prediction if the assumption holds that all households/users are homogeneous under the same electricity use pattern. If this is not reasonable, then disaggregate features allow us to examine household/user-
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703, 369, 13, 858, 253, 7227, 789, 15, 1621, 27042, 28, 247, 8388 ]	avery began. He smiled habitually as a matter of business, and tried to be polite to everybody, even to the beggar to whom he refused a penny. He had the look of a weazel, and the mien of a man of letters. He had a strong resemblance to the portraits of the Abbé Delille. He affected drinking with waggoners. Nobody ever saw him drunk. He smoked a large pipe. He wore a smock, and under it an old black tuxedo coat. He made pretensions to literature and materialism. There were names which he often pronounced in support of anything whatever that he might say. Voltaire, Raynal, Parny, and, oddly enough, St. Augustine. He professed to have "a system." For the rest, a great swindler. A _filou-sophe. be_ There is such a variety. It will be remembered, that he pretended to have been in the service; he related with some pomp that at Waterloo, being sergeant in a Sixth or Ninth Light something, he alone, against a squadron of Hussars of Death, had covered with his body, and saved amid a shower of grapeshot, "a general dangerously wounded." Hence the flamboyant picture on his sign, and the name of his inn, which was spoken of in the region as the "tavern of the sergeant of Waterloo." He was liberal, classical, and a Bonapartist. He had contributed to the homeless shelter. It was said in the village that he had studied for the priesthood. We believebf that he had only studied in Holland to be an innkeeper. This mongrel cur was, according to all probability, some Fleming of Lille in Flanders, a Frenchman in Paris, a Belgian in Brussels, conveniently on the fence between the two frontiers. We are acquainted with his prowess at Waterloo. As we have seen, he exaggerated it a little. Ebb and flow, wandering, adventure, was his element; a violated conscience is followed by a loose life; and without doubt, at the stormy epoch of the 18th of June, 1815, Thénardier belonged to that species of marauding canteen owners of whom we have spoken, scouring the country, robbing here and selling there, and travelling in family style, man, woman, and children, in some rickety carry-all, in the wake of marching troops, with the instinct to attach himself always to the victorious army. This campaign over, having, as he said, some funds, he had opened an eatery at Montfermeil. These funds, composed of purses and watches, gold rings and silver crosses, gathered at the harvest time in the furrows sown with corpses, did not form a great total, and had not lasted this canteen owner, now become a tavern-keeper, very long. Thénardier had that indescribable stiffness of gesture which, with an oath, reminds you of the barracks, and, with a sign of the cross of the seminary. He was a fine talker. He was fond of being thought learned. Nevertheless, the schoolmaster remarked that he made mistakes in pronunciation. He made out travellers' bills in a superior style, but practised eyes sometimes found them faulty in orthography. Thénardier was sly, greedy, lounging, and clever. He did not disdain servant girls, consequently his wife had no more of them. This giantess was jealous. It seemed to her that this little, lean, and yellow man must be the object of universal desire. Thénardier, above all a man of astuteness and poise, was a rascal of the subdued order. This is the worst species; there is hypocrisy in it. Not that Thénardier was not on occasion capable of anger, quite as much as his wife; but that was very rare, and at such times, as if he were at war with the whole human race, as if he had in him a deep furnace of hatred, as if he were of those who are perpetually avenging themselves, who accuse everybody about them of the evils that befall them, and are always ready to throw on the first comer, as legitimate grievance, the sum-total of the deceptions, failures, and calamities of their life—as all this leaven worked in him, and boiled up into his mouth and eyes, he was frightful. Woe to him who came within reach of his fury, then! Besides all his other qualities, Thénardier was attentive and penetrating, silent or talkative as occasion required, and always with great intelligence. He had somewhat the look of sailors accustomed to squinting the eye in looking through spy-glasses. Thenardier was a statesman. Every new-comer who entered the tavern said, on seeing the Thénardiess: There is the master of the house. It was an error. She was not even the mistress. The husband was both master and mistress. She performed, he created. He directed everything by a sort of invisible and continuous magnetic action. A word sufficed, sometimes a sign; the mastodon obeyed. Thénardier was to her, without her being really aware of it, a sort of being apart and sovereign. She had the virtues of her order of creation; never would she have differed in any detail with "Monsieur Thénardier"—nor—impossible supposition—would she have publicly quarrelled with her husband, on any matter whatever. Never had she committed "before company" that fault of which women are so often guilty, and which is called in parliamentary language: discovering the crown. Although their accord had no other result than evil, there was food for contemplation in the submission of the Thénardiess to her husband. This bustling mountain of flesh moved under the little finger of this frail despot. It was, viewed from its dwarfed and grotesque side, this great universal fact: the homage of matter to spirit; for certain deformities have their origin in the depths even of eternal beauty. There was somewhat of the unknown in Thénardier; hence the absolute empire of this man over this woman. At times, she looked upon him as upon a lighted candle; at others, she felt him like a claw. This woman was a formidable creation, who loved nothing but her children, and feared nothing but her husband. She was a mother because she was a mammal. Her maternal feelings stopped with her girls, and, as we shall see, did not extend to boys. The man had but one thought—to get rich. He did not succeed. His great talents had no adequate opportunity. Thénardier at Montfermeil was ruining himself, if ruin is possible at zero. In Switzerland, or in the Pyrenees, this penniless rogue would have become a millionaire. But where fate places the innkeeper he must browse. It is understood that the word _innkeeper_ is employed here in a restricted sense, and does not extend to an entire class. In this same year, 1823, Thénardier owed about fifteen hundred francs, of pressing debts, which rendered him moody. However obstinately unjust destiny was to him, Thénardier was one of those men who best understood, to the greatest depth and in the most modem style, that which is a virtue among the barbarous, and an article of commerce among the civilised—hospitality. He was, besides, an admirable poacher, and was counted an excellent shot. He had a certain cool and quiet laugh, which was particularly dangerous.bg His theories of innkeeping sometimes sprang from him by flashes. He had certain professional aphorisms which he inculcated in the mind of his wife. "The duty of the innkeeper," said he to her one day, emphatically, and in a low voice, "is to sell to the first comer, food, rest, light, fire, dirty linen, servants, fleas, and smiles; to stop travellers, empty small purses, and honestly lighten large ones; to receive families who are travelling with respect: scrape the man, pluck the woman, and pick the child; to charge for the open window, the closed window, the chimney corner, the sofa, the chair, the stool, the bench, the feather bed, the mattress, and the straw bed; to know how much the mirror is worn, and to tax that; and, by the five hundred thousand devils, to make the traveller pay for everything, even to the flies that his dog eats!" This man and this woman were cunning and rage married—a hideous and terrible pair. While the husband calculated and schemed, the Thénardiess thought not of absent creditors, took no care either for yesterday or the morrow, and lived passionately in the present moment. Such were these two beings. Cosette was between them, undergoing their double pressure, like a creature who is at the same time being bruised by a millstone, and lacerated with pincers. The man and the woman had each a different way. Cosette was beaten unmercifully; that came from the woman. She went barefoot in winter; that came from the man. Cosette ran up stairs and down stairs; washed, brushed, scrubbed, swept, ran, slaved, got out of breath, lifted heavy things, and, puny as she was, did the rough work. No pity; a fer
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3808, 9, 301, 10, 426, 4328, 551, 187, 50262, 1059, 941, 64, 881, 426, 1777, 25417, 3233, 28, 187, 50262, 2309, 3808, 9, 38031, 44804, 551, 2654, 13, 941, 64, 881, 6824, 187, 50266, 94, 187, 50270, 94, 535, 50270, 2309, 8256, 28, 187, 50274, 94, 535, 50274, 10638, 34895, 271, 11104, 432 ]	and her work.[16][17] Vanga incorrectly predicted that the 1994 World Cup soccer final would be played between "two teams beginning with B". Some say that she foretold it that way because of the penalty that Bulgaria wasn't given. One finalist was Brazil, but Bulgaria was eliminated by Italy in the semifinals.[18] Vanga predicted that a World War III will start in November 2010 and last until October 2014.[19][20] However, according to close friends, Vanga was not the type to voice predictions she saw if they were catastrophic because she knew that chaos that would ensue around those she told. Witnesses and close friends also claim that she never made such prophecies, and in fact when asked claimed that there will be no World War III.[17][21] Nevertheless, after North Korea — a nuclear nation — attacked South Korea on 23 November 2010,[22] there was a spike in internet interest about Vanga concerning this alleged prophecy.[23] Vanga attempted to prophesy about newborn or unborn children. She said that she was "seeing" and "talking" to people, who had died hundreds of years ago. Vanga talked about the future, although she did not like to. In her words, in 200 years man will make contact with brothers in mind from other worlds. She said that many aliens have been living on the earth for years. They came from the planet, which in their language is called Vamfim, and is the third planet from the Earth. Followers of Vanga believe that she predicted the precise date of her own death,[17] dreaming that she would die on 11 August, and be buried on 13 August. Shortly before that she had said that a ten-year-old blind girl living in France was to inherit her gift, and that people would soon hear about her.[citation needed] Apart from prophesying, Vanga was believed to be a healer, but only through herbal medicines. According to her, people had to heal themselves only with herbs from the country they live in. She prescribed washing with an infusion of herbs and spices, claiming some beneficial effect on the skin. Vanga did not oppose mainstream medicine, although she thought that taking too much medicines is bad, because "they close the doors, through which nature restores the balance in the body with herbs."[citation needed]. Accounts on the predictions of Vanga are often controversial and distorted by the media. One recent attempt to systematically summarize the existing knowledge about Vanga was made in the documentary "Vanga. The visible and invisible world".[16][24] The movie includes interviews with some of the people who met Vanga in person, including Sergey Medvedev (press secretary to President of RussiaBoris Yeltsin in 1995–96; Sergey Medvedev visited Vanga as Yeltsin's envoy following Vanga's request to meet her), Neshka Robeva (Bulgarian rhythmic gymnast and coach), Sergey Mikhalkov (Soviet and Russian writer, author of the Soviet Union anthem), Nevena Tosheva (director of the first documentary about Vanga), Kirsan Ilyumzhinov (Kalmyk multi-millionaire businessman and politician). According to the documentary, Baba Vanga predicted Yeltsin's second electoral victory in 1995, and warned him about his heart condition. Several researchers have studied the phenomenon of Vanga in the attempt to establish whether she has any extraordinary capabilities. One of the first studies was initiated by the Bulgarian government and is described in the 1977 movie Fenomen[25] directed by Nevena Tosheva. Prominent Bulgarian psychiatrists Nicola Shipkovensky and Georgi Lozanov also studied the capabilities of Vanga. Reportedly, some of the studies concluded that about 80% of predictions of Vanga turned out to be accurate.[26] Vanga was widely known to be close to the government of Todor Zhivkov and, on several occasions, she appeared on public TV with him and other high officials of the Bulgarian Communist Party. The daughter of Todor Zhivkov befriended Baba Vanga in the late 60s or early 70s and she was protected by the communist state thereafter, which apparently used the situation to its own advantage, with or without knowledge of Baba Vanga. It has been alleged that Vanga used data gathered by the secret services to win the trust of her visitors, who came to her by state-orchestrated appointments made well in advance. Baba Vanga was very popular and the Bulgarian state decided to organize her services and charge for them, giving Baba Vanga a state salary which was a tiny fraction of the earnings. Lists of people who were coming to see Vanga were formed by appointment, organized by the state, from the early 70s; as her fame rose, many foreign and domestic politicians were also visiting Vanga, and the house in which she worked was reportedly bugged. Members of the secret service worked in her environment, and she may have been manipulated to give suggestions to visiting politicians.[16] Vanga is well known in the Russian-speaking world. Some Russian nationalists[who?] consider her a true prophet of God[citation needed] and use her alleged prophecies of an upcoming nuclear war and Russian victory to argue for more robust defense policy and, more generally, for a more optimistic view of Russia's future.[citation needed] On the other hand, many Christians[who?] reject her as a spiritist and a false prophet who acted on behalf of the Devil. Thus there is a widely propagated story of Vanga becoming enraged at a visiting cleric (Nathanael, metropolitan of Nevrokop) carrying a holy relic, saying that this presence prevented her from prophesying.[citation needed] ^According to Encyclopædia Britannica Eleventh Edition, at the beginning of the 20th century the Bulgarians constituted the majority of the population in the whole region of Macedonia. They are described in the encyclopaedia as "Slavs, the bulk of which is regarded by almost all independent sources as Bulgarians": 1,150,000, whereof, 1,000,000 Orthodox and 150,000 Muslims (the so-called Pomaks); Turks: ca. 500,000 (Muslims); Greeks: ca. 250,000, whereof ca. 240,000 Orthodox and 14,000 Muslims; Albanians: ca. 120,000, whereof 10,000 Orthodox and 110,000 Muslims; Vlachs: ca. 90,000 Orthodox and 3,000 Muslims; Jews: ca. 75,000; Roma: ca. 50,000, whereof 35,000 Orthodox and 15,000 Muslims; In total 1,300,000 Christians (almost exclusively Orthodox), 800,000 Muslims, 75,000 Jews, a total population of ca. 2,200,000 for the whole of Macedonia.use std::fs::File; use std::io::Read; use std::marker::PhantomData; use std::mem; use std::path::Path; use std::str; use crate::context::{Context, GLintptr, Program, Shader, UniformLocation}; use crate::resource::{GLPrimitive, GPUVec}; #[path = "../error.rs"] mod error; /// Structure encapsulating a program. pub struct Effect { program: Program, vshader: Shader, fshader: Shader, } impl Effect { /// Creates a new shader program from two files containing the vertex and fragment shader. pub fn new(vshader_path: &Path, fshader_path: &Path) -> Option<Effect> { let mut vshader = String::new(); let mut fshader = String::new(); if File::open(vshader_path) .map(\|mut v\| v.read_to_string(&mut vshader)) .is_err() { return None; } if File::open(fshader_path) .map(\|mut f\| f.read_to_string(&mut fshader)) .is_err() { return None; } Some(Effect::new_from_str(&vshader[..], &fshader[..])) } /// Creates a new shader program from strings of the vertex and fragment shader. pub fn new_from_str(vshader: &str, fshader: &str) -> Effect { let (program, vshader, fshader) = load_shader_program(vshader, fshader); Effect { program, vshader, fshader, } } /// Gets a uniform variable from the shader program. pub fn get_uniform<T: GLPrimitive>(&self, name: &str) -> Option<ShaderUniform<T>> { let ctxt = Context::get(); let location = ctxt.get_uniform_location(&self.program, name); if ctxt.get_error() == 0 { if let Some(id) = location { let data_type = PhantomData; return Some(ShaderUniform { id, data_type }); } } return None; } /// Gets an attribute from
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<lazypower> --force will allow you to override that and get past it, but its erring on the side of caution for you <lazypower> i'm referring to the constructed charm <lazypower> the artifact <aisrael_> lazypower: removing that fixed it. Should I open a bug? * lazypower is doing a terrible job of explaining htis <lazypower> nah its intended behavior <lazypower> if you run with -l DEBUG <lazypower> it tells you what its matching on i think <aisrael_> lazypower: Right, the previous build left the layers.yaml in $JUJU_REPOSITORY/trusty/mycharm. Bad artifact. <lazypower> :) <aisrael_> lazypower: so a build copies over the charm, rather than replacing or rsyncing, right? <lazypower> the one thing build doesn't do, is take care of removal <lazypower> say you remove an interface from layer.yaml, then re-run build - you need to implicitly rm -rf the built charm and then build, otherwise that interface will linger <lazypower> aisrael_ correct, there are different strategies at play <aisrael_> lazypower: ack. I can see an argument for doing that cleanup automatically, even if it's an extra flag <lazypower> like config.yaml, metadata.yaml get merged <lazypower> other files have a default policy of highest layer that has this file wins. <aisrael_> i.e, if I'm writing a charm in layers/, I'd expect that to be authoritative <lazypower> so whatever your top layer is, will override files below it, save for a handfull of special files. and your local layer takes precedence over the interfaces.juju.solutions api yes but only if you have LAYER_PATH set <lazypower> same with INTERFACE_PATH <aisrael_> like the charm equivalent to make clean <lazypower> yeah <aisrael_> Caffeinated ramblings. Thanks for the help unblocking me! <lazypower> seems like charm build --clean should just nuke the compiled dir if exists then build. <lazypower> NP thanks for the questions :) <Icey> how hard would it be to change the AMIs used by Juju to be something that's EBS optimized? <aisrael_> lazypower: I am now a layer convert (not that I wasn't a fan before). <lazypower> :) <aisrael_> well, layer + reactive <lazypower> Layer + reactive is a powerful tool <lazypower> aisrael_ : https://github.com/mbruzek/layer-k8s/pull/5 <aisrael_> Niiiiice <lazypower> working on a feature branch with matt for the last 2 days, working independently there have been zero merge conflicts - putting complexity in its place :) <lazypower> and the change sets are getting smaller <aisrael_> lazypower: lxc now builds for os x, so if we can run lxd in a container... we might be closer to having a working local provider. <lazypower> nice! <aisrael_> I'll poke around at it tonight when I'm back home. <marcoceppi> lazypower: +1 to a --clean flag where it removes the previous build <marcoceppi> helpful when heavily devving <lazypower> I'll feature rq it <lazypower> https://github.com/juju/charm-tools/issues/33 <cholcombe> can you combine all your juju actions code into one file and symlink it just like the hooks? <marcoceppi> cholcombe: yes <cholcombe> marcoceppi, nice :) <cholcombe> so i do the usual @hooks.hook business <marcoceppi> cholcombe: welllll <marcoceppi> cholcombe: no one has tried that, they're not hooks, they're actions, so it's hard to say if that code will respect that <marcoceppi> cholcombe: for now it's probably better to just make a python module and then stub the import/execute of that module/methods in each file <cholcombe> marcoceppi, if i remember right at the code i looked at it just calls the hook with the matching filename that it was called with <marcoceppi> cholcombe: sure, but actions are not in the hooks directory <cholcombe> oh i know <marcoceppi> so if there's any attempt to parse out hook related file paths <marcoceppi> it'll fail <cholcombe> hmm yeah * cholcombe goes back to splitting them up #juju 2015-10-29 <vila> mgz_: ping <vila_> mgz_: ping <sharan> Hi <sharan> If i have deployed for example abc/0,abc/1,abc/2,abc/3 and abc/4 <sharan> in relation-changed hook is it possible for me to get abc/4 unit directly instead of using relation-list <vila_> mgz_: ping :-} <sharan> Hi i have abc/0,abc/1,abc/2,abc/3 and abc/4 units, Is it possible for me to get the highest number unit in this case like abc/4 in relation-changed hook directly without using relation-list <sharan> Hi i have abc/0,abc/1,abc/2,abc/3 and abc/4 units, Is it possible for me to get the highest number unit in this case like abc/4 in relation-changed hook directly without using relation-list <vila_> mgz_: Ping <cory_fu> jose: Hey, you have ethercalc locked on the RQ. Are you currently looking at that, or should I take a look? <aatchison> Hello. I am having difficulties while bootstrapping JuJu. After node aquisition and deployment on our MaaS cluster, I get this error: Attempt 1 to download tools from https://streams.canonical.com/juju/tools/releases/juju-1.24.7-trusty-amd64.tgz... <aatchison> curl: (7) Failed to connect to streams.canonical.com port 443: Connection timed out <aatchison> tools from https://streams.canonical.com/juju/tools/releases/juju-1.24.7-trusty-amd64.tgz downloaded: HTTP 000; time 126.855s; size 0 bytes; speed 0.000 bytes/s Download failed..... wait 15s <aatchison> I can curl to that address and get the file, any ideas? <aatchison> I am using ppa:juju/stable and ppa:maas/stable on 14.04. <aatchison> Sorry, I timed out. I donât know if anyone responded or not :/ <pmatulis> nope <alexisb> aatchison, if you are still around, could this potentially be your issue: http://askubuntu.com/questions/465508/juju-bootstrap-debug-failed-to-connect-https-streams-canonical-com <aatchison> ahh, thank you <aatchison> checking that out <moqq> anyone have any idea what i should do if one of the jujud agents out of nowhere refuses to start up with this error: âpanic: runtime error: invalid memory address or nil pointer dereferenceâ <moqq> full logs: http://paste.ubuntu.com/13002509/ <moqq> was thinking it might be related to https://bugs.launchpad.net/juju-core/+bug/1496188 but iâm not really sure <mup> Bug #1496188: panic in juju worker <panic> <juju-core:Triaged> <https://launchpad.net/bugs/1496188> <moqq> if i have an agent with message âmessage: agent is not communicating with the server" <moqq> i just want to delete that unit <moqq> but remove-unit does nothing <moqq> (WHY?!?!) #juju 2015-10-30 <gennadiy> hi all, i have question about removing aws security groups: seems juju doesn't remove security group when machine is removed. am i right? and today i have got exception: security groups number limit is reached <gennadiy> do we need to remove security group manually? do you have some specific config field to reuse security groups
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187, 187, 61, 423, 92, 3306, 94, 535, 510, 4477, 6583, 326, 13, 323, 7012, 4606, 13, 690, 2289, 13133, 4647, 281, 253, 941, 6944, 253, 4342 ]	731(2), 362 S.E.2d 768. Appellant, after being duly notified of both the calendar *217 call and the court call voluntarily elected not to take action either to obtain his timely presence in court or to provide for an authorized representative to appear on his behalf at these proceedings. The bench trial was held on August 8, 1996. Appellant received a copy of appellees' motion for bench trial and to strike his defensive pleadings on August 6, 1996; however, he did not file his objections until August 12, 1996, after the bench trial was held. Neither did appellant inform the court of any difficulties nor communicate to the court in any manner, regarding the calendar call or subsequent call of the case to trial. By this repetitive conduct, which ultimately resulted in the striking of his entire defensive pleadings, appellant implicitly waived his right to trial by jury. Compare Goss, supra; see also Robertson v. Central Mut. Ins. Co., 165 Ga.App. 167, 299 S.E.2d 894; Galanti v. Emerald City Records, 144 Ga.App. 773, 774(2), 242 S.E.2d 368. This holding is consistent with the well-established appellate rule that on appeal a party cannot complain of a judgment or ruling of the trial court which his own conduct or legal strategy aided in causing. Williams v. Food Lion, 213 Ga.App. 865, 868, 446 S.E.2d 221. Green v. Snellings, 260 Ga. 751, 400 S.E.2d 2 is distinguishable; although incarcerated, appellant had ample notice of both the calendar call and the court call, and he also had prior notice of appellees' motions to dismiss appellant's defensive pleadings and for bench trial. Appellant already had filed a demand for a jury trial; he did not need express notice of the bench trial to safeguard his opportunity to make such demand. The case at bar, unlike Green, supra, involves the issue of waiver of an existing demand for trial by jury. In view of this holding, we need not address the issue of harmless error. Compare Newman v. Greer, 131 Ga.App. 128, 131-132, 205 S.E.2d 486. Judgment affirmed. ELDRIDGE, J., and HAROLD R. BANKE, Senior Appellate Judge, concur. President Trump said Thursday that he is considering 15 candidates to replace John Bolton as national security adviser, the day after he told reporters that there were only five contenders for the position. Mr. Trump will announce his pick sometime next week, he said Wednesday. "A lot of people want the job. It's a great job. It's a lot of fun to work with Donald Trump. It's easy because I make all the decisions," Mr. Trump said of the 15 people he said were under consideration. On Wednesday, Mr. Trump had said, "I have five people that want it very much." He called the candidates "good people I've gotten to know" during his tenure. The president added that he would "be announcing somebody next week." Get Breaking News Delivered to Your Inbox Mr. Trump announced over Twitter Tuesday that he had "informed John Bolton" that "his services are no longer needed" and that he had asked for Bolton's resignation. Mr. Trump reiterated that he had disagreed with Bolton on several issues, including Bolton's desire to take the "Libyan model" to North Korea. In 2018, Bolton said on "Face the Nation" that he was "looking at the Libya model of 2003, 2004" as a model for a nuclear deal with North Korea. In 2003, Libya had negotiated sanctions relief from the United States in exchange for renouncing its nascent nuclear program. Eight years later, Libyan leader Muammar Gaddafi was overthrown in a gruesome killing by Western-backed rebels. Mr. Trump considered this remark a "very big" mistake. "You just take a look at what happened with Gaddafi. That was not a good statement to make," he said. "And it set us back." President Trump has had three national security advisers so far: Michael Flynn, H.R. McMaster and Bolton. Kathryn Watson contributed to this report.(CNN) The nation's 38 million food stamp recipients will get their February benefits early amid the partial government shutdown. State officials say their allotments will be loaded onto electronic benefit transfer cards by Sunday, rather than next month. That's the only way the federal government can make the payment since the program initially wasn't funded beyond January. The US Department of Agriculture announced last week that it is using a provision allowing it to make obligated payments within 30 days of a government funding lapse. The shutdown began after funding ran out December 21. The change has left states racing to issue the February benefits -- which are expected to total $4.8 billion -- by January 20. Typically, states issue benefits over the course of a month, in part to make sure grocery stores have enough food and to provide them with a steady stream of customers. Households receive $245 a month, on average. State officials are working closely with the federal agency to speed up payments, and all are expected to be able to comply, said Ann Flagg, director of the Collaborative Centers for Policy & Practice at the American Public Human Services Association, which represents state and local health and human service agencies. Read MoreShowing 1 to 6 of 6 Quiz 2 The following are sources of information on laws or regulations concerning biotechnologyrelated activated or products. Spell out the meaning of each. Circle the site where you can actually comment on proposed laws. USC: United States Code eCFR: ele BTEC 3317 - Homework 1 Put your name and student number on the first line of all assignments The second line will be a relevant title for your homework Then your answers begin on the 3rd line. Go to: http:/www.accessdata.fda.gov/scripts/fcn/fcnNavigation. BTEC3317W Homework6 Orphan Drugs for Rare Diseases There will be no group presentation for next week. 1. Go to: http:/www.fda.gov/ForIndustry/DevelopingProductsforRareDiseasesConditions/Howtoapplyf orOrphanProductDesignation/ucm364750.htm a. Give a brief Biotechnology Regulatory Environment Flashcards Showing 1 to 1 of 1 What is the daily official publication of the US government where all newly proposed and final federal rulemaking (including regulations) can be accessed, and where the public can comment on proposed laws?TNW Sites Twitter advertisers can now target ads based on the apps a user has installed After an announcement that it would begin tracking users’ app installs almost two weeks ago, Twitter has begun to allow advertisers to use that data to target users more directly and reach the most valuable audiences. The functionality is a little more in depth than originally anticipated, however. For example, in addition to app installs, marketers can look at which apps a user has registered or made purchases within. This could allow them to continually remind forgetful users to sign up, or persuade them into buying into a special promotion. Twitter says it has already begun testing this functionality with some brands and has received positive feedback on its usefulness. Still, many users won’t be happy about companies knowing what they’re doing with their apps , so they can disable the ‘feature’ by unchecking the box for ad tailoring in the Twitter app’s privacy settings. The company also says it respects the “limit ad tracking” setting on iOS and the “opt out of interest based advertising” option on Android.Q: Environ's body doesn't allow for making an \item As part of a document process/workflow, it's easier to work with environments. However, in some cases the environment contents needs specific formatting. As such, it's convenient to use the environ package to capture the environment \BODY, and then use it as needed. The following elementary implementation doesn't work though: \documentclass{article} \usepackage{environ} \NewEnviron{HEADING}{% \item[\BODY] } \begin{document} \begin{description} \begin{HEADING} Heading \end{HEADING} \end{description} \end{document} How can I get around to having environment HEADING process it's \BODY as an argument in the expected way? A: You have to execute \item[...] outside the environment, because it must be at the outer level in a list. The reason is that \item does \@item, which sets \everypar; having it in a group would cause every sort of problems. \documentclass{article} \usepackage{environ} \NewEnviron{HEADING}{% \expandafter\gdef\expandafter\THISHEADING\expandafter{% \expandafter\item\expandafter[\BODY]% }% \aftergroup\THISHEADING } \begin{document} \begin{description} \begin{HEADING} Heading \end{HEADING} Something to follow \end{description} \end{document} The authors confirm that, for approved reasons, some access restrictions apply to the data underlying the findings
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6503, 3646, 326, 4245, 10865, 370, 18, 3041, 275, 4465, 9781, 1223, 597, 457, 250, 6276, 15, 773, 1147, 310, 436, 1524, 6330, 273, 2564, 323, 776, 4212, 1806, 344, 2296, 15, 380, 5700, 310, 2444, 27, 1503, 22369, 457, 84, 643, 20500, 13, 1503 ]	end did not work. 747 N.W.2d 276 (2008) PEOPLE of the State of Michigan, Plaintiff-Appellee, v. Lewis HARRIS, Defendant-Appellant. Docket No. 135630. COA No. 271929. Supreme Court of Michigan. April 28, 2008. On order of the Court, the application for leave to appeal the December 20, 2007 judgment of the Court of Appeals is considered, and it is DENIED, because we are not persuaded that the questions presented should be reviewed by this Court. Former 'Apprentice' contestant battles Trump in defamation lawsuit hearing Kevin McCoy \| USA TODAY Show Caption Hide Caption Attorney: President is not above the law A former cast member of the reality TV show 'The Apprentice' who has accused Donald Trump of unwanted sexual contact and has filed a New York defamation lawsuit against him has thanked her lawyers and says the case should go forward. (Dec. 5) NEW YORK — The lawsuit filed against President Trump by a former contestant on The Apprentice who accused him of groping and then defaming her moved a step closer Tuesday to a decision on whether the case should go to trial. In clashing court arguments, lawyers for Summer Zervos said she suffered threats after Trump publicly said she had "made up" her claims in a politically motivated effort to help Hillary Clinton beat him in the 2016 presidential race. Trump "cannot be allowed to attack a woman who has factually described his sexual groping and be allowed to get off scot-free," argued Zervos attorney Mariann Meier Wang during the hour-long hearing before Manhattan Supreme Court Justice Jennifer Schecter. Marc Kasowitz, Trump's personal lawyer, contended that Trump said nothing wrong while defending himself. He also argued that the case cannot legally be tried in state court, and should be dismissed or at least delayed. Citing the U.S. Constitution's supremacy clause, he said Trump's motion to throw out the case "has nothing to do with putting anyone above the law." Instead, he said it was about "protecting the ability of the president to do his constitutionally-mandated job." Schecter did not issue an immediate ruling on the dismissal motion, saying she would study the court arguments and legal briefs before making a decision in the potentially precedent-setting case. Zervos, who sat quietly in the lower Manhattan courtroom behind her attorneys, is among roughly a dozen women who publicly accused Trump of sexual misconduct during last year's presidential race. But she's the first to sue him. Filed in January, her legal action alleges that Trump “ambushed” her more than once in 2007, six years before he was elected president, by kissing her on the mouth, touching her breast, and pressing his genitals against her. Zervos also accused Trump of defaming her during campaign rallies and via Twitter, his favorite social media platform. At an Oct. 15, 2016, campaign stop in Maine, Trump alluded to Zervos by referring to "false allegations and outright lies, in an effort to elect Hillary Clinton President," the lawsuit charges. Woman who accused Trump of groping her files lawsuit Summer Zervos accused Donald Trump of groping her, and she filed a defamation lawsuit after he called her accusations a lie. Video provided by Newsy Trump has denied Zervos' allegations, which echo other women’s claims. Trump has dismissed them as false. During Tuesday's court hearing, Kasowitz contended that Trump's statements about Zervos were constitutionally protected remarks in which he defended himself. Trump's attorneys are relying on some of the legal arguments then-President Bill Clinton's lawyers made when he was accused in a 1994 federal court lawsuit over an alleged sexual assault. Paula Jones alleged that the attack took place in 1991 when she was an Arkansas state employee and Clinton was the state's governor. More: Trump borrows Bill Clinton's legal strategy as he battles defamation lawsuit The U.S. Supreme Court allowed that case to proceed in federal court. After a four-year legal battle, Clinton agreed to pay an $850,000 settlement. Both sides in the Zervos case said there has been no definitive ruling whether a sitting U.S. president may be sued in a state court over allegations that do not involve official White House duties. Kasowitz cited a footnote in the Supreme Court's Clinton-Jones decision to support his argument that the Zervos case must be dismissed or postponed until Trump's presidential term has ended. The footnote stated that “any direct control by a state court over the president ... may implicate concerns that are quite different” from the issues in the Jones case. When Schecter asked whether he believed that she would be unable to preside over the lawsuit, Kasowitz responded, "not with respect to the President, your honor." Schecter noted that the footnote "leaves the question open," without deciding the issue. "What better court to hear a defamation case against a born and bred New Yorker," who some of the allegedly improper statements just a few miles from the courthouse, argued Wang. Wang added that Zervos' legal team would accommodate Trump by scheduling sworn depositions from him around his White House schedule — or even holding them in between presidential golf outings at his Mar-a-Lago Florida estate. Kasowitz declined to comment after the hearing. Zervos said little publicly other than thanking her attorneys. As she made their way through a crowd of TV and still photographers, co-counsel Gloria Allred said Zervos had shown "admirable courage" in challenging Trump. Follow USA TODAY reporter Kevin McCoy on Twitter: @kmccoynycThe “mega trend” that swallowed Silicon Valley FORTUNE — It’s 8 a.m. on a Thursday, and a message pops up on Nancy Tcheou’s iPhone. It shows a map of downtown San Francisco with the exact location of a guy she’s never met named Zach Lagod. Her red Honda Civic is easy to spot with a furry pink mustache covering the bumper. She pulls up, greets Lagod by name, and the two do a fist-bump “hello.” Lagod jumps in the front seat, and they’re off to the train station 15 minutes away. The two make small talk, as Lagod flips through songs on the radio. Tcheou is not Lagod’s friend, and she is not a professional taxi driver. She’s an unemployed 25-year-old who happens to have time on her hands and a car filled with gas. So she signed up to give strangers a ride in her car using a new mobile ridesharing service called Lyft. It’s one of a flood of new startups that aim to create online and mobile social networks that let people share in the real world. There are apps that find and borrow power tools from your neighbors, that let you rent a nearby stranger’s car or hire someone close by to pick up dog food. You can go online to rent your parking spot when you’re not using it or you can find a home for your dog when you travel. Call it the new share economy or as its known in the industry: the collaborative consumption movement. Airbnb led the way. The site, which lets people rent their homes to travelers, has booked more than 10 million nights in 192 countries since its start in 1998, and last year it generated an estimated $58 million. Now people are taking a look at any under-used assets they may have, whether it’s an empty seat in their car and time on their hands, or a bike sitting in the garage, a vacant parking space in their driveway, an empty cubicle at their office or a power saw seldom used. And they’re sharing, borrowing or renting them. “People are looking around and saying, ‘Hey, I can rent out my car. I can share my skills. I don’t need to own a designer dress, I can rent one,’” says Rachel Botsman, author of What’s Mine is Yours: The Rise of Collaborative Consumption. “There is a big shift underway from the ‘me’ of hyper-consumption to the ‘we’ culture of collaborative consumption.” The Internet and mobile technology are driving that shift. Some 78% of people say they’re far more inclined to share with strangers in the offline world because of social networking. Smart phones add a new layer, giving you instant access and location data about who is nearby. Add in people’s environmental consciousness and thriftiness in the economic recession, and demand grows even more. Security remains a big issue for many of these peer-to-peer startups following disaster stories of people whose homes got trashed after using Airbnb. At Lyft, drivers must be 23 or older, have a driver’s license for more than three years and pass background check and DMV record checks, says Lyft’s co-founder John Zimmer. People’s cars must be clean, newer and checked for safety, and both drivers and passengers must have credit cards, Facebook FB accounts and GPS capabilities on their phone for security. Ratings are key too. If your average rating is low, then your account is closed. Zimmer says he worked for more than three months to develop an insurance policy that gives drivers $1 million in extra liability while they’re driving. “It is this real peace of mind for our users,” he says. The strategy is working: Zimmer’s other startup, Z
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Solve u - h = -bu for u. 4 Suppose 25s - 76 = 199. Solve 12 = -sx - 21 for x. -3 Let w = 11 + -8. Let a = 13 - w. Suppose -a = -v - 4v. Solve 5s = vs for s. 0 Let t(f) be the second derivative of -f3/6 - 2f*2 + f. Let u be t(-10). Let z = u + -6. Solve 5l + 2 + 3 = z for l. -1 Let h = -25 + 29. Suppose -5l - b + 3 = -1, 3b - 12 = -hl. Solve t = -3 - l for t. -3 Let v(y) = -9y + 35. Let t be v(4). Let i be ((-1)/t)/(4 + 102/(-26)). Solve -3c - 4 + i = 0 for c. 3 Let b be ((0/3)/(-1))/(-2). Suppose -2d + 7 = 5j, b = -5j + 5d + 45 - 10. Solve -2i - ji + 5 = 0 for i. 1 Let p be -1(72/(-20))/((-6)/(-15)). Let w = -8 + 14. Let k(b) = b*3 + 5b*2 + 2b - 3. Let i be k(-4). Solve -p - w = -iq for q. 3 Let y(j) = j3 + 8j*2 - j - 6. Let q be y(-8). Let d be (0 - (q + 0))/((-4)/4). Solve 0 = dx - 6x - 16 for x. -4 Let x = 571 - 564. Solve 8z + x = -33 for z. -5 Let w = -74 + 127. Let v = w + -48. Let k(a) = -11a3 - a2 - a - 1. Let h be k(-1). Solve h + v = -5c for c. -3 Let g = 1599 + -1594. Solve -8o + 26 = go for o. 2 Suppose -4t + 24 = 2q + 2q, 45 = 4q - 3t. Suppose 4j + 5 - q = 0. Let x = -5 + 8. Solve xr + 5 + j = 0 for r. -2 Let y(j) = j3 - 4j*2 - 4j - 5. Let r be y(5). Suppose 0 = -3m + 5h + 44, -h - 4h + 12 = 4m. Solve i - 3i + m = r for i. 4 Suppose 4b - 2b - 18 = 0. Let i(g) = g - 9. Let x be i(b). Let t be (-3 + -1)(-22)/44. Solve x = 5n - 3 - t for n. 1 Suppose -13v + 70 = -229. Let s = v - 20. Solve 8n - sn = 15 for n. 3 Let l(x) = -x*3 + 13x*2 + 16x - 24. Let r be l(14). Solve 0 = -3t + 2t + r for t. 4 Suppose 0 = 3u + 4w - 23, 5u - 47w - 85 = -42w. Solve ub = 15b for b. 0 Suppose 0 = 4h - 2h - 6. Suppose 0 = -hb + 5b - 36. Suppose 5r = 5n + 50, 5r + 4 = -4n + b. Solve rp + 3 = 3p for p. -1 Let y(w) = -w - 3. Let v be 14 + (3 - -1 - 4). Let l be y(v). Let q = 24 + l. Solve q + 2 = -3p for p. -3 Suppose -5u + 4w = -0w - 25, 20 = 4u - 5w. Solve u + 25 = 6z for z. 5 Let h(g) be the second derivative of -g*5/10 + 25g4/6 - g3/6 + 13g2 + 43g. Let k be h(25). Solve 5s - k = 6s for s. -1 Suppose 0 = -4g - 8o + 3o - 6, -g = -2o - 5. Suppose g = -f - 6. Let z(k) = -k*2 - 10k - 9. Let u be z(f). Solve u = 3t - 3 for t. 5 Let f(a) = -a - 1. Let h(c) = 15. Let g(y) = 4f(y) - h(y). Let s be g(-6). Solve 0 = -sz + z for z. 0 Let u(o) be the third derivative of o4/12 - 6o*3 - 4o*2. Let f be u(19). Solve -2n = fn + 8 for n. -2 Let d(u) = u2 - 10u - 9. Let w be d(7). Let s be (w/9)/(1/9). Let j be (12/s)/((-1)/5). Solve jf - 4f = 0 for f. 0 Let l = 483 - 444. Solve -26a + 13a = l for a. -3 Let l(z) = -2z2 - 13z + 34. Let i(r) = 3r2 + 27r - 67. Let p(n) = -3i(n) - 5l(n). Let j be p(14). Solve 0 = -4x + jx + 3 for x. 3 Suppose -4q + 50 = q + x, -x = -2q + 20. Let w(f) = -f*2 + 4f + 1. Let o be w(3). Let p be (q/o)/((-7)/(-14)). Solve pv = 2 - 7 for v. -1 Let s = -25 - -25. Suppose -p + 2p = s. Solve 3 = -j - pj for j. -3 Let t(m) = m2 - 57m - 645. Let j be t(-10). Solve 19 = -2u + j for u. 3 Let q = 658 - 658. Solve q = 3w - 2 - 10 for w. 4 Let b be (-134)/2144 - (-386)/32. Solve 6r - 12 = br for r. -2 Suppose -7o + 8o - 2 = 0. Let b be (-2)/(-4)o2. Solve 2 = -bl - 2 for l. -2 Let n be (-738)/(-36) - 1/2. Solve -69s + 73s - n = 0 for s. 5 Let m(a) = -a3 + 4a*2 + 4a - 6. Let c(k) = -k*2 + 4k + 9. Let j be c(5). Let d be m(j). Solve -d = 3f - 1 for f. -3 Let k(m) = -50m - 830. Let y be k(-19). Solve -125g + yg = 5 for g. -1 Let j be 4/(-6) + 1184/(-24). Let p = j + 75. Let z = -23 + p. Solve 1 = -x + z for x. 1 Let d = -417 - -421. Solve -20 = da - 8a for a. 5 Let s be 1/41/(-2)-16. Suppose -su + 4u - 6 = 2j, 2j = u - 6. Solve 5x - 3x + 10 = u for x. -5 Let t be (-2 + -1)(-2)/3. Suppose -tc = -5c. Let u(g) = 7g*2. Let r be u(-1). Solve 2o - ro - 25 = c for o. -5 Suppose 8l + 12l = 880. Solve 3u = -l + 32 for u. -4 Let v(z) =
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Quite a savings for just a few clicks huh? That shows just how easy it is to find and use an HP coupon code. Hope this helps. Now go save some money.[A case of adenosquamous gastric carcinoma successfully treated with TS-1, low-dose CDDP and docetaxel as neoadjuvant chemotherapy]. The patient was a 66-year-old male with extremely advanced gastric cancer type 3 and diagnosed with adenocarcinoma by endoscopic biopsies specimens. Combined chemotherapy of TS-1, CDDP and docetaxel was prescribed in order for tumor reduction and downstaging. TS-1 (80 mg/m(2)) was administered 28 days followed by 14 days rest as one course. CDDP (8 mg/m(2)) was administered on days 1, 2, 14 and 15 and docetaxel (40 mg/m(2)) was administered on day 1 and 14, followed by 4 weeks rest as one course. After 2 courses of treatment, a CT scan revealed a minor response of tumor reduction. Therefore, total gastrectomy, partial pancreas body and tail resection, and D 2 lymph node dissection were performed. The patient had undergone adjuvant chemotherapy of TS-1 and biweekly docetaxel after surgery with no recurrence for 13 months. Adverse reactions were grade 3 neutropenia and grade 2 diarrhea. Combined chemotherapy of TS-1, low-dose CDDP and docetaxel were intensive and required constant patient monitoring. However, it proved effective and feasible as a neoadjuvant chemotherapy regimen for advanced gastric cancer.Adaptive filtering and random variables coefficient for analyzing functional magnetic resonance imaging data. Functional magnetic resonance imaging (fMRI) is used to study brain functional connectivity (FC) after filtering the physiological noise (PN). Herein, we employ: adaptive filtering for removing nonstationary PN; random variables (RV) coefficient for FC analysis. Comparisons with standard techniques were performed by quantifying PN filtering and FC in neural vs. non-neural regions. As a result, adaptive filtering plus RV coefficient showed a greater suppression of PN and higher connectivity in neural regions, representing a novel effective approach to analyze fMRI data.Cheap NFL Jerseys China of Lot 636 Topoo Backdam Police are reportedly closing in on the killers of security guard/ businessman Gowchand Budhu, who was shot dead last Saturday at his Topoo, Corentyne home.Budhu, 58, of Lot 636 Topoo Backdam,2018 Nike Air Max 97, Albion, Corentyne, Berbice was allegedly slain at around 20:20 hrs,Cheap Jerseys From China, by two bandits who had invaded his home.His wife Parbattie Budhu,Atlanta Hawks Jerseys, 54, was badly beaten and treated at the Anamayah Memorial Hospital before being sent home.After the incident, investigators arrested one man from the area and kept him in custody. However, after intense investigation, he was released on station bail.Meanwhile,Cheap Wholesale Jerseys, police are following a number of leads and appear confident that they are making inroads in the investigation. Arrests are expected soon.A post mortem examination by Pathologist Dr. Vivikanand Brijmohan at the Port Mourant Hospital concluded that Budhu died from shock and haemorrhage due to gunshot injuries.Budhu operates a chicken farm at his home while also working as a security guard at the Albion Front Primary School. The family also operates a grocery shop and a beer garden in an adjoining building in the lower flat at the front of yard. That business is operated by the wife.Injured: Parbattie BudhuDead: Gowchand BudhuThe victim’s wife has said she had taken a bath and was about to enter the lower flat when two masked and armed bandits confronted her.The bandits were allegedly clad in their briefs only with the bodies covered in mud and were wearing coloured toque masks.She said one of the intruders gun-butted and punched her, while ordering her to be quiet.Gowchand, who had retired to bed, reportedly heard the commotion and his wife’s cries and hurried downstairs.The husband, a licensed firearm holder, reportedly raced back upstairs and grabbed his 12 gauge shot gun. He was reportedly heading back to the lower flat when he was shot a number of times by one of the bandits who had mounted the inner stairs.After shooting Gowchand, the bandits reportedly fled the scene empty handed.The woman had told investigators that she did not know how she reached upstairs,Wholesale NFL Jerseys, and after regaining consciousness,Cheap NFL Jerseys, found herself lying in the living room next to her husband.The man’s shotgun with two cartridges was found next to his body.The police also recovered a number of 12 gauge cartridges, a revolver and a number of rounds.View full sizeEverton Bailey Jr./The OregonianLake Oswego Councilor Bill Tierney announced on Tuesday he is withdrawing support for a proposed Portland streetcar line extension into the city. The announcement from the elected official, who had the swing vote when the city council pushed the proposal forward last April, likely means a delay to Lake Oswego streetcar plans indefinitely. The Portland-Lake Oswego streetcar project appears to be dead -- or at least suspended -- after losing suburban political support. "Until we are more united as a city, as a region, and as a city council, I believe we should in the near term, put this project on the shelf," said Tierney. "Leave it for a future council to examine if they choose to and cease direct expenditures in the foreseeable future." Tierney cited a weak economy, a deep split in public opinion and a need for Lake Oswego officials to focus on more immediate city needs as his reasons for changing his mind. He also mentioned that he informed Mayor Jack Hoffman of his decision before announcing it at the meeting. "We need to further refine what our community should be," said Tierney. "Right now, this council is too divided to move ahead with bold plans." Councilor Sally Moncrieff, another firm supporter of the project, also appeared to be withdrawing her support on Tuesday saying she agreed with Tierney that now is not the right time for a streetcar in Lake Oswego. "I still believe very firmly that the streetcar project is an excellent project and that's it's the right project for Lake Oswego but it's always been contingent on being financially feasible," she said. "It takes all of the partners being ready to go at the same time." The streetcar proposal was the most high-profile of available options presented in the Lake Oswego to Portland Transit Project. The initiative looked to present transit alternatives to alleviate traffic congestion along Oregon 43. An enhanced bus system was another option that was on the table. The Lake Oswego streetcar proposal encountered opposition from many city property owners who expressed concerns over issues such as the project's initially projected $458 million price tag by a planned completion date in 2017 to potential quality of life and environmental concerns. A community survey conducted late last year of 300 registered Lake Oswego voters found 52 percent of respondents opposed the project. View full sizeThe OregonianPlans for a Portland streetcar extension into Lake Oswego took a hit on Tuesday after Lake Oswego Councilor Bill Tierney announced he no longer supported the project. The move likely puts the project on hold indefinitely. However, supporters of the plan believed the streetcar could be the key to revitalizing the city's population and economic opportunities. The Lake Oswego City Council approved a framework plan in late November to redevelop the city's 107-acre Foothills district into a mixed-use area for housing, retail and offices with the streetcar as one of its main attractions. Hoffman, who voted last year for the city to continue exploring the streetcar option, said the advisory vote and other issues will have to be re-evaluated in the coming days and weeks. "I still think this is a great project, as everybody knows," said Hoffman on Tuesday. "I think the timing is problematic with the economy, TriMet's issues and other issues. But I think we need to keep in mind the transportation land use connection and that Foothills is still a project we need to keep moving forward on." Former Lake Oswego Mayor Judie Hammerstad, a strong streetcar proponent, said she’s hard-pressed to think of a better transit alternative for the city. “It’s my view that this is a project that doesn’t have to happen today, but it’s got to happen in the next few years,” she said. “I don’t see any other transportation projects for Lake Oswego that can bring to the table what the streetcar can – and the window to do it is closing.” Councilor Gudman said he had no idea Tierney's announcement was coming but applauded his colleague for "having a change of heart." "It's always difficult for someone to change their mind," said Gudman after the meeting. "But this now permits us to move forward and use our limited resources on a variety of other projects that could be much more beneficial to Lake Oswego." "But the project is dead, there's really no need to gloat," he added. Councilor Mary Olson, another streetcar opponent, said she would have liked to have seen an announcement like this come a year ago. "It's a good thing this is coming to an end," she said. "
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18379, 2544, 497, 16307, 13, 342, 247, 2074, 1180, 273, 443, 31, 34, 285, 330, 31, 53, 35225, 15, 380, 2074, 3894, 273, 443, 31, 34, 285, 330, 31, 53, 16307, 6492, 247, 3480, 273, 8492, 275, 253, 8706, 273, 473, 9, 23, 4587, 13006, 4297, 21222, 10429, 875, 3882, 30450, 15, 1707, 369, 13, 2299, 13, 247, 2266, 13005, 273, 253, 18379, 8704, 253, 473, 9, 23, 4587, 1405, 40, 387, 253, 428, 18 ]	stress (WAS) daily for 10 consecutive days. The abdominal withdrawal reflex (AWR) to colorectal distension was assessed at the end of the 10-day period. Western-blotting analysis was applied to investigate the alterations of TRPV1 and TRPA1 in the colonic afferent dorsal root ganglia (DRG). Compared with control rats, the WAS-treated rats demonstrated a significant increase in the AWR with the pressure > or = 40 mm Hg (P < 0.05). Meanwhile, in the WAS-treated rats, western-blotting analysis showed significant upregulation of TRPV1 and TRPA1 in the colonic afferent DRG. The results indicate that WAS could induce the upregulation of TRPV1 and TRPA1 in the colonic afferent DRG, and both receptors may be candidate molecules involved in the stress-induced visceral hyperalgesia in rats.Connie Morella Visits Law Library on March 18, 2009 Former Maryland Congresswoman Connie Morella Discusses Her Legislative Experience Working for Women, Children and Families On Wednesday, March 18, acting Law Librarian of Congress Charles Doyle and Associate Librarian of Congress Deanna Marcum will welcome the Honorable Constance ‘Connie’ Morella as she presents “Legislating in Heels – An Anecdotal Journey.” The event will take place between 1:00 and 2:30 pm at the Whittall Pavilion, located in the Jefferson Building on 1st Street SE between Independence Avenue and East Capitol Streets in Washington, D.C. When she began her lengthy tenure in Congress in 1987, there were only 24 women in the House. Upon her departure 16 years later, that number increased to 62. Her presentation will be a fitting tribute to the accomplishments of women during National Women’s History Month. Prior to her service as Ambassador to the Organization for Economic Cooperation and Development from 2003 to 2007, Ms. Morella served in Congress, chairing the Congressional Caucus for Women’s Issues and sponsoring the 1992 Battered Women’s Testimony Act and the Judicial Training Act, both having important repercussions for women in the court system due to domestic violence. Ms. Morella also served in the Maryland House of Delegates from the 16th District. The event is free and open to the public but seating is very limited and advance reservations are suggested at (202) 707-9834, [email protected]. Request ADA accommodations five business days in advance at (202)707-6362 or [email protected] Founded in 1832, the Law Library of Congress makes its resources available to members of Congress, the Supreme Court, other branches of the U.S. Government and the global legal community, and sustains and preserves a universal collection of law for future generations. With more than 2.6 million volumes, the Law Library contains the world’s largest collection of law books and other resources from all countries and provides online databases and guides to legal information worldwide through its Web site.Mustang Original Studded Seat Overview of Mustang Original Studded Seat Mustang Motorcycle Products, Inc. is a world leader in the design and construction of motorcycle seats. Since 1980, Mustang has been proud of making the highest quality, most comfortable seats available and offering them at reasonable prices. Mustang motorcycle seats are designed for all-day riding comfort for both the driver and passenger. Every Mustang seat is made in the United States by true craftsmen who take pride in transforming the highest quality, raw materials into a finished product. Full front bucket for comfort Passenger seat angles forward to support drivers back Functional skirt flows over frame and fender to give a smooth, clean looktalkingrobocop's podcast Wherein Kit Power watched the movie Robocop with a different guest each month and records the resulting conversation. Occasional bonus podcasts feature returning guests picking a different movie to watch. Made possible entirely as a result of Patreon funding - www.patreon.com/kitpower. Sign up for only a $1 a month for early access and exclusive content. Categories Welcome to the fourth episode of Watching Robocop with Kit Power! This month, I am delighted to be joined by Renee Pickup, a superb author, non-fiction writer, blogger and podcaster with strong opinions and excellent taste in movies. Join us, and discover: Renee's 'not enough violence in movies' theory Kill Bill and why you never dis Con Air An exciting new fan theory about Clarence's nose And SO much more. Enjoy! And as ever, thank you for your support. :) For more of Renee's blogging and podcasting, please head on over to her webpage. My monthly Ginger Nuts Of Horror blog ‘My Life In Horror’, which kicked off this whole thing, can be found here. Theme tune provided with the kind permission of The Disciples of Gonzo, from their track Superhero. Listen to more from them here. If you enjoyed this podcast and would like to contribute financially to the monthly production costs, in exchange for early access to both this show and my written work, as well as snazzy exclusives, please see my Patreon. Welcome to the first ever bonus episode of the podcast! Thanks to the amazing generosity of my Patreon backers, I am going to be releasing these bonus episodes on a bi-monthly basis, in which returning guests get to pick THEIR favourite movie to talk about. In our first bonus 'cast, Daniel Harper returns to talk about his childhood love affair and obsession with Terminator 2: Judgement Day. Amongst many revelations, discover: How there are, in fact, only two Terminator movies Vonnegut's holy word Kit outing himself as a human chauvinist And much, much more. Enjoy! :) For more of Daniel's blogging and podcasting, please head on over to his page on Eruditorum Press. My monthly Ginger Nuts Of Horror blog ‘My Life In Horror’, which kicked off this whole thing, can be found here.The present invention relates to an improved mounting arrangement for a measuring device of the type comprising a measuring scale, a carrier which supports the measuring scale, and at least one clamping element for fasting the carrier to a mounting surface of one of two objects, the relative position of which is to be measured. German Pat. No. 27 12 422 discloses a length measuring system which includes a housing that surrounds the measuring scale and the scanning unit. This housing is fastened by means of screws to a machine part. German Pat. No. 25 05 585 discloses a length measuring system in which a housing, which encloses both the scale and the scanning unit, is fastened at both ends to a machine part by means of angle brackets which define in the vertex region a joint in the form of a groove. German Pat. No. 26 30 880 discloses a length measuring system in which the housing, which encloses both the scale and the scanning unit, is fastened at both ends to an object to be measured by means of ball joints. In the measuring systems described above, precisely positioned bores must be provided for the fastening of the housing to the object to be measured, both in the housing and also in the object. The formation of such precise bores represents a considerable expense in many applications. The document "Messen und Prufen/Automatik", July and August 1974, page 438, FIG. 12a, discloses a known practice for fastening a scale to a narrow supporting surface of a machine part by means of clamping shoes positioned at one side of the scale. In this arrangement high contact pressure forces of the clamping shoes against the scale are needed to hold the scale carrier in engagement on the supporting surface in the face of vibrations and joltings of the machine. German DE-OS No. 38 08 384 discloses a measuring arrangement in which a scale carrier defines on both side surfaces a lateral groove. Clamping shoes engage this lateral groove in order to fasten the scale carrier to a machine part. This arrangement provides a secure seating of the scale carrier on the machine part, but is relatively expensive in construction and requires considerable space to implement.Molecular analysis of point mutations in a barley genome exposed to MNU and gamma rays. We present studies aimed at determining the types and frequencies of mutations induced in the barley genome after treatment with chemical (N-methyl-N-nitrosourea, MNU) and physical (gamma rays) mutagens. We created M(2) populations of a doubled haploid line and used them for the analysis of mutations in targeted DNA sequences and over an entire barley genome using TILLING (Targeting Induced Local Lesions in Genomes) and AFLP (Amplified Fragment Length Polymorphism) technique, respectively. Based on the TILLING analysis of the total DNA sequence of 4,537,117bp in the MNU population, the average mutation density was estimated as 1/504kb. Only one nucleotide change was found after an analysis of 3,207,444bp derived from the highest dose of gamma rays applied. MNU was clearly a more efficient mutagen than gamma rays in inducing point mutations in barley. The majority (63.6%) of the MNU-induced nucleotide changes were transitions, with a similar number of G>A and C>T substitutions. The similar share of G>A and C>T transitions indicates a lack of bias in the repair of O(6)-methylguanine lesions between DNA strands. There was, however, a strong specificity of the nucleotide surrounding the O(6)-meG at the -1
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273, 253, 38598, 6456, 2758, 18274, 3579, 1902, 5954, 15, 187, 187, 3, 1466, 441, 1908, 253, 20558, 3398, 347, 597, 403, 3063, 15, 1281, 441, 1908, 795, 20513, 64, 20558, 3398 ]	citizens, hear me! I have discovered evidence — undeniable, incontrovertible proof of this very conspiracy!" The audience surged and muttered, their cries blending into a dull roar. I remembered the crowd on the day of the Funeral Riot — the many-headed enemy. The City Guards moved forward, positioned to intercept any movement from the audience, but Orelia held them back with a signal. They'd be no help if things got too tight. For right now, we — Terris and I — were down here and the crowd was up there, and we had a precious little space between us. Not even a pea-brained twitterbat would call that an advantage. On a signal from Montborne, a City Guard marched down a side aisle and up to the table. Had Montborne somehow gotten Orelia to do his dirty work for him? The Guard wore a patch over one eye and carried two long, slender leather-wrapped bundles. I didn't like the look of this at all. Neither, apparently, did the rest of the Inner Council. A few of the Senators rose to their feet in protest. At my side, Terris turned pale. The one-eyed Guard unwrapped the two bundles and laid them on the table in front of the general. I did not need to look to know what they were. One of them had an official-looking card tied to it. Montborne picked up the tagged dagger. With a dramatic flourish, he lifted it overhead, the slender blade catching the light, and laid on the oval table. "This is the norther dagger that killed Pateros! "And this — " he picked up the second blade and held it high, with exactly the same gesture. If I'd blinked, I wouldn't have known it was different except for the tag fluttering like a rock-dove pinion. The crowd held its breath as he set the second dagger down. "Unbelievable as it sounds, yesterday this _exact duplicate_ was smuggled into Laureal City — " The audience rumbled like an avalanche about to bust loose. Montborne held them back with a gesture. " — and discovered, hidden... _in the possession of that man!_ " He whirled and pointed straight at Terris. # Chapter 40 Montborne's voice thundered above the general outcry. "I accuse Terricel sen'Laurea, who just yesterday returned from a secret mission to our norther borders." Esmelda stood motionless, as she had through Montborne's entire speech, but now the Councillor in the fancy neck chain pushed forward and gestured for order. Terris tensed, ready for action. I grabbed his shoulder and held him firm. Anything he said would only make things worse. It was only one small step to ask _Who sent Terris north?_ Montborne meant to bring Esmelda down as well, or else tie all Laurea into knots trying. By the time things got sorted out, he aimed to be in control, and no one would remember that Esmelda had also made accusations against him. "These allegations are outrageous!" cried Hobart, the fancy-chained Councillor. "Outrageous and monstrous!" "But if they're true?" demanded Orelia, rising and pounding the table so that water splashed from the silver ritual bowl. _"What if they're true?"_ Ah, so that was how Montborne had gotten to her. " _Truth?_ You want the truth?" Quick as a striking snake, Esmelda seized the opening. Any other time, the old dragon might have gotten the room back under her control. The Inner Council would have listened, as well as half the Senators. I caught the flashes of unguarded feeling on their faces, fear and suspicion warring with the bone-deep need to believe in her. But the crowd at the back and up on the balconies, the many-headed monster, wavered on the very edge of riot. "Truth is not something to be determined by a popularity contest." Esmelda's voice sliced through the uneasy murmurs. "Montborne has raised some very serious charges, charges that bear on the very heart and future of our nation. These charges merit the most thorough and careful investigation. How can we possibly do them justice here, bandying them about like a pack of irresponsible playground insults?" A few people in the front rows sat down again. A Senator in the front row wiped his florid cheeks with a handkerchief, as if the sudden reversal was too much for him. "These allegations will be heard in the proper time and setting," Esmelda went on, " _as well as_ evidence that the weapons produced by Montborne were manufactured right here in Laureal City — in a secret military facility — under the orders of General Montborne himself." "Impossible!" Montborne shot back, still brandishing the second dagger. "Any fool can see these are _norther_ daggers!" "If the distinguished general will kindly —" Hobart, the Senate Presidio, tried again. Esmelda made a slashing gesture with her hands. Suddenly the doors under the spectators' balconies flew open. Head high, Avi strode down the wide central aisle, Jakon and Grissem only a pace behind her. In their quilted vests and elkskins, their hair like spun gold, faces stern, they seemed proud and strange but not, as Montborne said, savage. I'd fought as hard as anybody at Brassaford, I'd spilled as much blood, but I knew now what _savage_ really was. The entire chamber went wild — people screaming, jumping up and waving their arms, ushers vainly trying to calm them, Senators and Councillors calling for order, the priest chanting, Montborne's men looking confused and astonished, some of them unnerved — the whole mess worse than a barnfowl coop after a raptor bat has just swooped in, and twice as brainless. A bunch of spectators rushed for the doors, but Orelia motioned her people forward. They moved quickly to hold back the worst of the panic. Me, I was on my feet with one hand on my long-knife hilt and the other on Terris's shoulder, grimly counting how many throats I'd have to cut to get him out of there alive. In front of the oval Inner Council table, Esmelda waited, still as a carven statue. The two northers had turned round to face the audience, Avi between them. They stood, legs apart, balanced lightly on the balls of their feet, arms folded across their chests. It was too bad, I thought, that Jakon couldn't dance for the crowd — then they'd really sit up and notice. How it happened, I didn't know — whether it was something Esmelda did or the strength of her presence or the northers' inhuman calm, or maybe just plain curiosity winning out over batshit stupidity, but the room grew quiet again. People cleared the aisles and sat down, some still pointing and whispering to their neighbors, others hushing them up. Montborne glanced around — he knew the moment had gone to Esmelda. Behind that waxy-smooth face, I sensed him juggling for another opening, trying to outguess what she'd try next. Esmelda's voice was intense, but clear and low, as if she had no need to shout or make dramatic gestures. It was enough to talk as she did about desperate times, about hope and dreams. She was no Pateros, even I saw that. Pateros could take someone like me and make me think I could do great things — Esmelda made these people think _she_ could. For this time and place, though, it was enough. If Avi could do the same thing, she could also sign that treaty with Jakon's people, marry him, and bear a half-norther heir to succeed her as Guardian. Maybe there was a chance for peace with the north after all. After a moment or two, I caught the change in the faces of the crowd. Most of them were children when Esmelda stood out there on the plaza and the rains came down to put out the foundry fires and the plague ended. Yet they seemed to somehow remember, as if that history were bred into their blood. As if to underscore the mystery of Jakon and Grissem, she began by reminding the audience of the long history of conflict between Laurea and the north. Times I'd never heard of, not being a scholar, things that happened hundreds of years ago. And Brassaford. Ah yes, these people remembered Brassaford. A murmur passed through the room like a gust of bitter wind and then as quickly died down. If Jakon or Grissem felt it, they gave no outward sign. "And so, we come to the present," Esmelda said. "To here and now. To today." A few people in the balconies grumbled, impatient for answers to the questions Montborne had raised. The Senators, who knew the rhythms of official speech, settled down to listen. Orelia and some of the Inner Council members leaned forward expectantly. "Let us consider the northers as they are today. Let us consider _these_ northers
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Handcrafted by a women's cooperative in India that employs low-income women. Size: 21" in length with 2.5" extender Learn more about WorldFinds and the artisans who made this product. Three strands of upcycled Kantha fabric beads are punctuated by a larger bead, and come together with a brushed gold metal ring at the center. Uneven, linear rows of Kantha beads hang from the ring, forming a fringe. Each necklace will vary slightly, as the Kantha beads are repurposed. The beads are made by wrapping Kantha fabric around tiny wooden beads. Handmade by women artisans in India who improve their lives and communities through fair trade. Size: Measures 26” long plus a 2” extender. Learn more about WorldFinds and the artisans who made this product. Large, lightweight golden hoop earrings featuring colorful beads made from recycled Kantha fabric wrapped around wooden beads. Colors and patterns will vary slightly. Handmade by women artisans in India who are working to improve their lives through fair trade. Size: 3" from top of earring Learn more about WorldFinds and the artisans who made this product. Three geometric points of recycled Kantha beads hang below a strand of brass triangles. Each necklace will vary slightly, as the Kantha beads are repurposed. Handmade by women artisans in India who are improving their lives and communities through fair trade. Size: 20"; with 2" extender Learn more about WorldFinds and the artisans who made this product. Three strands of recycled Kantha textile beads are linked with gold metal wires and complimented by gold chain fringe hanging from the longest strand. Each necklace will vary slightly, as the Kantha beads are repurposed. Handmade by women artisans in India who improve their lives and communities through fair trade. Size: Measures 16” at shortest strand + 4 ½” extender. Learn more about WorldFinds and the artisans who made this product. This graduated strand of recycled kantha beads alternate with tiny golden beads to form a necklace that crescendos at the center. Colors and patterns vary, but each necklace is vibrant. Handcrafted by a women's cooperative in India that employs low-income women. Size: 22" in length with 2.5" extender Learn more about WorldFinds and the artisans who made this product. This colorful rainbow kantha bracelet comes with a tag which reads, "Unity encourages harmony and intention. This Unity Bracelet inspires us to trust that together we are greater than the sum of our parts." Measures ¼”; stretches to fit most wrists. Sustainably handmade by women artisans in India who are working to improve their lives through fair trade. **Learn more about WorldFinds and the artisans who made this product. Festive stars made from nickel-plated brass with glass panels on front and back, and open on the sides. They make a lovely glow when lit with an LED candle. Comes on a 15" chain with hook for hanging. LED tea lights recommended.Murders that many saw coming Ahn In-deuk didn’t look good.And his older brother knew that could mean trouble - violent trouble.It was early this month, and the older brother - who asked that his name be withheld in interviews with the JoongAng Ilbo - concluded that the 42-year-old Ahn was on a downward spiral. He needed to do something before Ahn caused harm, as he had in the past.The older Ahn phoned a psychiatric hospital in Jinju, South Gyeongsang, on April 5. He wanted to have his brother hospitalized.He asked the Jinju hospital for records showing that Ahn was treated there for schizophrenia for six months from late 2011. The older brother was also trying to disguise his own role in having his younger brother hospitalized - in case he retaliated someday.The hospital made clear it could not help, no matter how hard he insisted. The older Ahn needed to produce a power of attorney for his brother - or the younger Ahn had to personally visit the hospital to claim his records.Twelve days later, the younger Ahn poured gasoline around the living room of his fourth floor apartment in Jinju, set fire to a piece of newspaper and hurled it on the flammable liquid at around 4:30 a.m. He walked down to the second floor of his building and allegedly stood near a staircase, stabbing neighbors trying to escape to safety.Five were killed, including a 12-year-old girl, and six were injured.His older brother had been correct. Ahn descended into homicidal madness.Ahn’s neighbors are criticizing local police for having ignored their complaints about his increasingly erratic and disturbing behavior. Neighbors called the police number, 112, six times since he moved into the apartment complex in Jinju in December 2015. Most of the calls were made within the past year.Yet Ahn was charged only a single time for property damage after he was caught on CCTV throwing his own feces at the door of an upstairs neighbor. That was on March 12 - a month before the fire and killings. The CCTV was installed by the neighbor to gather proof of Ahn’s threats. Ahn was caught on camera following the neighbor’s 18-year-old niece, who was living in the apartment. That niece was fatally stabbed allegedly by Ahn on March 17.Now, the suspect’s brother is taking a jab at the country’s medical system, claiming he tried to force the younger Ahn into receiving treatment in the weeks before the tragedy, but failed due to red tape.The first time Ahn was officially diagnosed with schizophrenia was 2010, after he was criminally charged with slashing a college student he didn’t know in the face with a knife in downtown Jinju. He was convicted of assault, sentenced to two years in prison with a three-year probation, and sent to the National Forensic Psychiatry Hospital in Gongju, South Chungcheong, a mental hospital run by the Ministry of Justice for criminals with mental illnesses.After Ahn was discharged, his family forced him into a psychiatric hospital in Jinju in late 2011. Families of a schizophrenic patient can hospitalize their relative if, among other circumstances, two immediate family members agree to the admission. After six months of treatment, Ahn was discharged in 2012. Through July 2016, he received outpatient treatment from the Jinju hospital.That was the last medical attention Ahn ever sought. He told his family he didn’t want to take medication because it made him feel disoriented, especially at work.His symptoms grew worse and he began bullying his neighbors in mid-2018. His brother tried to help but Ahn refused to seek treatment. He held a grudge against his family after they forced him into the hospital in 2011.After the brother’s entreaties to the Jinju psychiatric hospital on March 5 failed, he got in touch with the local prosecutors’ office, wondering if it could force his brother to receive treatment. It was another dead end, and prosecutors told him to try the Jinju city government or the younger Ahn’s community center instead.The community center said it could do nothing. A worker at the community center said he previously worked for the city government and knew the system well. But he doubted Jinju City Hall could help with such a delicate and serious request.The older Ahn learned that, under the law, the Jinju mayor had the authority to force Ahn into hospitalization. He made a request, which was rejected for an unspecified reason.According to interviews conducted by the JoongAng Ilbo with numerous people who know the younger Ahn, including his mother, Ahn was introverted and didn’t have many friends as a young child, but didn’t get into trouble. The family was poor, and when Ahn graduated from middle school in 1993, he decided to start working. (High school education is not compulsory in Korea.) Ahn mostly worked in factories.In his early 20s, Ahn injured his back at a factory in Gimhae, South Gyeongsang. He tried to get compensation for the accident from the company, but failed.According to people who knew him, that’s when his personality took a turn for the worse.Ahn moved from one factory to another, until 2008, at age 31, he hurt his back again at a factory run by a conglomerate in Changwon, South Gyeongsang. Ahn applied for compensation again, and failed.He became angry.After he was discharged from the Gongju mental hospital in 2011, Ahn started punching passersby for no reason. Ahn has told police and the local press that he committed his alleged murders “out of anger” because he had been “disadvantaged” by the Jinju city government, society and former employers, without detailing how. Police are looking into the possibility that his failures to receive workplace compensation could have been the prime source of his rage.BY SHIN SUNG-SIK, LEE EUN-JI, KIM YOON-HO AND NAMGUNG MIN [[email protected]]I[NTRODUCTION]{.smallcaps} {#sec1-1} ========================== Congenital adrenal hyperplasia (CAH) describes a group of inherited autosomal recessive disorders affecting adrenal steroid synthesis. The most frequent CAH variant, accounting for 95% of all affected patients, is 21-hydroxylase deficiency (21-OHD) and caused by inactivating mutations in the 21-
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3072, 4038, 273, 898, 13, 20570, 7732, 591, 575, 10294, 15818, 313, 1508, 13, 26933 ]	ings can quote every line of both movies. "We've got the tools, we've got the talent. It's Miller time...." Smooth solve from here. Thanks, Dan. Once again, didn't get theme 'til it was over. I'll have to work on that. This oldstress did know Mortimer 1A SNERD with his nerdy buck-tooth and Jacques Brel (36A IFWE)who "is alive and well and living in" the minds of those who loved him. Wish you had a picture of the dummy, and a video of Brel (especially the really weird - or wired - "Amsterdam").Likewise, did not know 13A TAKEI or Lucy 20D LIU. Must learn. I liked this puzzle and thanks PG for the write up. ARRAS was familiar for several reasons. Years ago I saw the wonderful Arras tapestries in The Cloisters (part of Met. Mus. of Art) in NYC and I lived one summer on Rue d'Arras in Paris. Arras is also a city in northern France, the birthplace of Robespierre. Loved the reference to Pee Wee REESE a great player with the old Brooklyn Dodgers. I"ve had a CAT scan but didn't know AXIAL, and REFLUX, I don't want to talk about. ALGER HISS recalls the communist hysteria of th "50's. I like it when full names are in puzzles. ARRAS is a word i've only ever heard (and used) in the context of hamlet. polonius is hiding behind the ARRAS in gertrude's bedroom when hamlet hears him and stabs him through it. moral of the story: don't hide behind the ARRAS, especially when there's a moody armed dane milling about. this was one of my faster LAT paper solves; as soon as i got RUSSELL CROWE and the M of MUSSEL SHELL, i knew what the theme would be, and promptly wrote in RUSTLE CATTLE and MUSCLE CRAMP. the only thing that kept me from breaking a personal best was the fact that i originally tried to write in RUSSEL CROWE and ... it didn't fit. erasing cost me about 10 seconds, not much in the grand scheme of things, but when you've got your ears pinned back to go for maximum speed, that's a big deal. oh, and one other mild hangup: because it was a dan naddor, i was expecting AT IT AGAIN and CRAPSHOOT to be part of the theme also. but i'm actually pleased that they weren't, because those are great fill entries. I learned ARETE from crosswords. It should have a little hat (circumflex accent) over the first e....ARÊTE. According to online dictionaries, it is pronounced uh-RATE. Here is a photo of Half Dome in Yosemite National Park with Clouds Rest arête in the background. I worked this puzzle without any real trouble although I initially put NANO for Mork's signoff before remembering it's NANU. ARRAS was a new word for me and I had the same questions noted above re: GLADIOLA (gladiolus, gladioli, gladiolas, gladioluses?) I guess it's safe to call them glads. had reactions similar to those of sfingi, parsan, david; very pleasant puzzle, thank you Dan Naddor and even better write-up< PG! Guess I missed the Crosswordese on TETRA. And PSEUD? New one...Particularly liked: SNERD, ARRAS (now I know what they are), MACHISMO, ATITAGAIN, GLADIOLA, AXIAL, DILEMMA and ALGERHISS, which may have presented a real problem to those not of a certain age... For anyone who is interested in learning more about Alger Hiss, I recommend Sam Tanenhaus's (he edits the NYT Sunday Book Review) biography of Whittaker Chambers.. I too didn't really catch the pairing/rhyming of the theme until coming here. I see the first words rhyme but...And is it Edgar Allan Poe month? All said, another encouraging LA Times puzzle, beginning to atone for some recent let-downs- you know, the idiom "pin one's ears back" does not mean anything at all like what i thought it meant. at least according to online dictionaries. my mac's built-in dictionary says it means "to listen carefully." i can also find "to give a person a sound beating" and "to scold severely" for pin someone's ears back. it's also apparently a literal phrase for a type of elective surgery for people whose ears stick out. i have only ever heard it used to describe pass rushers in football, who are said to "pin their ears back" and go after the QB on obvious passing downs, abandoning any responsibility for stopping the run. i'm not exactly sure why this would help them (less air resistance, perhaps?), but idiom is a strange thing. trying to solve a puzzle on paper in under 3 minutes is a slightly frightening experience. i feel like i'm careening out of control much of the time, and it always seems like a small miracle if the letters even end up in the boxes, to say nothing of whether they're actually correct. When I was a young pup, my grandfather (one of the largest wholesale flower growers in the West) would have scolded me if I had ever called it GLADIOLA. One GLADIOLUS, more than one GLADIOLI, was the one true path. Or, when talking to the hired help, they were often just GLADS, as in "time to pick the glads." One of my slowest solves in ages...felt like I was solving in mud or something. Joon, I've watched a lot (A Lot) of football, and I don't remember _ever_ hearing that expression. There's a ton of support for it online (if you search with football, otherwise you just get bilateral otoplasty info), so I wonder why? I should say I've watched a lot of _pro_ football, maybe it tends to be a college expression? It's probably just that I'm not auricularly observant. Many animals "pin their ears back" as an indication of anger, intent to attack, or while attacking. It's a clear sign of iminent attack should a dog, cat, horse, etc. pin their ears back. Hence its comming into common usage to go on the attack. Further, in the animal world, it's a matter of self preservation - if your ears are pinned back, they're less likely to be bitten off in the ensuing fight. Or, in my case, they just stick out so damned far. @Joon - I used gum. Before I was dead and all. My left ear involuntarily goes back when I hear a loud noise behind me. (Throwback to ape ancestors.) I can also move it voluntarily. I used to think that "prick up your ears," referred to that, until I found it didn't happen to other people. @ddbmc -I would love to be able to embed. But, as far the circumflex, I have a Character Map which I load to the side, hit on the character, select it, and drop and drag. ê @Parsan. In the '60s, I was at the Cloisters viewing the Unicorn Tapestries which shows the capture of the unicorn (shut up Freud). A 4-yr-old girl was in front of the one showing the capture and wounding, and she was crying for the unicorn with her mother telling her the unicorn was ok. I marveled at the message sent across 5 centuries.I only know PeeWee Reese because his name rhymed with my sister's, so we had to hear it all the time. Alger Hiss is referred to at pumpkin time! Lick should be on the puzzle with RNA and DNA. @Embien - thanx for glad info. @Orange - I guess there are many new abbrevs. Back in my day, we didn't even have adolescent literature, so I took a 3-credit.Likewise, I'll have to find a newer list to study. seth, am i imagining things or did jaws use "pin their ears back" to describe freeney and mathis going after pennington in the 4th quarter last night? in any event, it's a turn of phrase i associate with football writers more than announcers. i think doug farrar over at football outsiders is the first one i can remember using it.South Delhi South Delhi is an administrative district of the National Capital Territory of Delhi in India. It is bounded by the Yamuna River to the east, the districts of New Delhi to the north, Faridabad District of Haryana state to the southeast, Gurgaon District of Haryana to the southwest, and South West Delhi to the west. South Delhi has a population of 2,731,929 (2011 census), and an area of , with a population density of 9,034 persons per km² (23,397
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'_mm_cmpnge_ss', '__builtin_ia32_cmpordss': '_mm_cmpord_ss', '__builtin_ia32_movss': '_mm_move_ss', '__builtin_ia32_movsd': '_mm_move_sd', '__builtin_ia32_movhlps': '_mm_movehl_ps', '__builtin_ia32_movlhps': '_mm_movelh_ps', '__builtin_ia32_movqv4si': '_mm_move_epi64', '__builtin_ia32_unpckhps': '_mm_unpackhi_ps', '__builtin_ia32_unpckhpd': '_mm_unpackhi_pd', '__builtin_ia32_punpckhbw128': '_mm_unpackhi_epi8', '__builtin_ia32_punpckhwd128': '_mm_unpackhi_epi16', '__builtin_ia32_punpckhdq128': '_mm_unpackhi_epi32', '__builtin_ia32_punpckhqdq128': '_mm_unpackhi_epi64', '__builtin_ia32_unpcklps': '_mm_unpacklo_ps', '__builtin_ia32_unpcklpd': '_mm_unpacklo_pd', '__builtin_ia32_punpcklbw128': '_mm_unpacklo_epi8', '__builtin_ia32_punpcklwd128': '_mm_unpacklo_epi16', '__builtin_ia32_punpckldq128': '_mm_unpacklo_epi32', '__builtin_ia32_punpcklqdq128': '_mm_unpacklo_epi64', '__builtin_ia32_cmpeqpd': '_mm_cmpeq_pd', '__builtin_ia32_cmpltpd': '_mm_cmplt_pd', '__builtin_ia32_cmplepd': '_mm_cmple_pd', '__builtin_ia32_cmpgtpd': '_mm_cmpgt_pd', '__builtin_ia32_cmpgepd': '_mm_cmpge_pd', '__builtin_ia32_cmpunordpd': '_mm_cmpunord_pd', '__builtin_ia32_cmpneqpd': '_mm_cmpneq_pd', '__builtin_ia32_cmpnltpd': '_mm_cmpnlt_pd', '__builtin_ia32_cmpnlepd': '_mm_cmpnle_pd', '__builtin_ia32_cmpngtpd': '_mm_cmpngt_pd', '__builtin_ia32_cmpngepd': '_mm_cmpnge_pd', '__builtin_ia32_cmpordpd': '_mm_cmpord_pd', '__builtin_ia32_cmpeqsd': '_mm_cmpeq_sd', '__builtin_ia32_cmpltsd': '_mm_cmplt_sd', '__builtin_ia32_cmplesd': '_mm_cmple_sd', '__builtin_ia32_cmpunordsd': '_mm_cmpunord_sd', '__builtin_ia32_cmpneqsd': '_mm_cmpneq_sd', '__builtin_ia32_cmpnltsd': '_mm_cmpnlt_sd', '__builtin_ia32_cmpnlesd': '_mm_cmpnle_sd', '__builtin_ia32_cmpordsd': '_mm_cmpord_sd', '__builtin_ia32_cvtsi642ss': '_mm_cvtsi64_ss', '__builtin_ia32_cvttss2si64': '_mm_cvtss_si64', '__builtin_ia32_shufps': '_mm_shuffle_ps', '__builtin_ia32_shufpd': '_mm_shuffle_pd', '__builtin_ia32_pshufhw': '_mm_shufflehi_epi16', '__builtin_ia32_pshuflw': '_mm_shufflelo_epi16', '__builtin_ia32_pshufd': '_mm_shuffle_epi32', '__builtin_ia32_movshdup': '_mm_movehdup_ps', '__builtin_ia32_movsldup': '_mm_moveldup_ps', '__builtin_ia32_maxps': '_mm_max_ps', '__builtin_ia32_pslldi128': '_mm_slli_epi32', '__builtin_ia32_vec_set_v16qi': '_mm_insert_epi8', '__builtin_ia32_vec_set_v8hi': '_mm_insert_epi16', '__builtin_ia32_vec_set_v4si': '_mm_insert_epi32', '__builtin_ia32_vec_set_v2di': '_mm_insert_epi64', '__builtin_ia32_vec_set_v4hi': '_mm_insert_pi16', '__builtin_ia32_vec_ext_v16qi': '_mm_extract_epi8', '__builtin_ia32_vec_ext_v8hi': '_mm_extract_epi16', '__builtin_ia32_vec_ext_v4si': '_mm_extract_epi32', '__builtin_ia32_vec_ext_v2di': '_mm_extract_epi64', '__builtin_ia32_vec_ext_v4hi': '_mm_extract_pi16', '__builtin_ia32_vec_ext_v4sf': '_mm_extract_ps' } # Special unhandled cases: # __builtin_ia32_vec_ext_*(__P, idx) -> _mm_store_sd/_mm_storeh_pd # depending on index. No abstract insert/extract for these oddly. unhandled = [ '__builtin_ia32_vec_ext_v2df', '__builtin_ia32_vec_ext_v2si', ] def report_repl(builtin, repl): sys.stderr.write("%s:%d: x86 builtin %s used, replaced with %s\n" % (fileinput.filename(), fileinput.filelineno(), builtin, repl)) def report_cant(builtin): sys.stderr.write("%s:%d: x86 builtin %s used, too many replacements\n" % (fileinput.filename(), fileinput.filelineno(), builtin)) for line in fileinput.input(inplace=1): for builtin, repl in repl_map.iteritems(): if builtin in line: line = line.replace(builtin, repl) report_repl(builtin, repl) for unh in unhandled: if unh in line: report_cant(unh) sys.stdout.write(line) sys.exit(err) After sinking over 60 percent from its December high to its February low, bitcoin is showing signs of life. The cryptocurrency is now up about 35 percent since it sank below $6,900 on Feb. 5, and one market watcher who correctly called the rally says there's even more room to run. After the Feb. 5 low, Blue Line Futures President Bill Baruch told CNBC's "Trading Nation" he saw a move up back up to $10,000. At that time, bitcoin was trading around $7,200. Tuesday morning, bitcoin was trading above $9,200, representing roughly 28 percent upside since that time. Here's his latest bull case. • Participation in the rally has been broad-based, with several so-called alt-coins gaining in value recently. This is seen as a bullish catalyst for the entire cryptocurrency space. • Bitcoin has seen a bounce from its 2018 lows even in the face of ongoing regulatory concerns, including a new inquiry from New York Attorney General Eric Schneiderman into exchanges like Gemini and Coinbase's GDAX exchange. • The $10,000 level has represented strong resistance, but once that level is breached to the upside, Baruch sees a trade around $11,500 per coin. Bottom line: Baruch sees further upside for bitcoin after a sizable rally from its 2018 lows.I just had my first MRI in April and I
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3195, 1196, 323, 521, 9732, 13, 40274, 276, 369, 1677, 281, 1333, 773, 1147, 457, 84, 512, 275, 19629, 1425, 2091, 352, 3249, 281, 15571, 253, 6495, 27675, 13, 581, 1537, 1333, 347, 973, 773, 262, 457, 84, 512, 275, 9221, 85, 5292, 1425, 187, 187, 2598, 309, 5194, 326, 6304, 543, 310, 9106, 17285, 275, 7291, 3006, 38734, 285, 521, 18409, 323, 4933, 824, 247, 19456, 8813, 273, 253, 6495, 27675, 13, 347, 604, 352, 497, 13, 323, 512, 540, 592, 285, 6378, 13, 1160, 275, 253, 1982, 13, 285, 347, 604, 253, 6495, 27675, 1904, 457, 85, 1663, 1265, 1919, 31039, 15, 1292, 253, 1895, 342, 38734, 310, 417, 13, 347, 6304, 543, 5936, 13, 326, 344, 31564, 441, 432, 253, 8936, 16039, 273, 6018, 37889, 285, 353, 26495, 715, 253, 5997, 273, 253, 6495, 27675, 15, 380, 1895, 310, 326, 38734, 17994, 2147, 253, 22669, 3762, 13, 1014, 2167, 253, 22669, 3762, 574, 2168, 644, 4307, 562, 323, 779, 604, 760, 344, 574, 28860, 281, 1239, 352, 15, 1292, 38734, 457, 84, 1600, 275, 253, 2892, 273, 22669, 3762, 858, 417, 9017, 1077, 2080, 13, 604, 387, 512, 13, 4457, 271, 689, 14092, 1984, 407, 521, 9732, 24395, 353, 23578, 329, 9541, 273, 6022, 272, 15977, 15, 187, 187, 1909, 323, 1880, 17940, 7466, 1925, 323, 407, 6018, 37889, 369, 3309, 281, 990, 253, 6495, 27675, 13, 359, 513, 871, 326, 253, 2234, 2803, 15571, 7355, 432, 253, 6495, 27675, 369, 6108, 253, 5328, 2629, 15, 1244, 253, 954, 1774, 1650, 273, 253, 6349, 273, 6108, 253, 5328, 2629, 310, 253, 13406, 18864, 273, 3453, 275, 253, 1982, 5068, 275, 4162, 26916, 313, 43574, 314, 1078, 7466, 552, 17940, 3646, 812, 1379, 1055, 10, 1563, 253, 13394, 273, 253, 5328, 2629, 407, 38140, 285, 271, 3576, 3387, 6, 372, 1208, 2368, 273, 253, 14838, 275, 2426, 273, 5328, 15, 17842, 4162, 285, 4163, 26916, 13, 9787, 3275, 275, 253, 1982, 2559, 407, 5571, 5294, 5739, 7911, 4829, 25128, 13, 8410, 9461, 407, 2030, 5294, 1223, 35222, 7911, 9461, 407, 1638, 7739, 1876, 326, 310, 3587, 26585, 281, 38140, 457, 84, 3061, 281, 1379, 253, 1982, 745, 5328, 13, 285, 372, 2877, 253, 14838, 313, 2887, 1060, 481, 12526, 13, 275, 4163, 26916, 13, 38140, 48134, 13313, 432, 253, 43567, 273, 10170, 313, 263, 9454, 432, 253, 43567, 273, 7355, 10, 407, 4983, 253, 3313, 34882, 13500, 13, 3692, 4767, 4736, 369, 313, 2277, 40, 13724, 281, 7164, 7911, 407, 7281, 293, 3006, 17057, 285, 34617, 3453, 13, 1223, 23254, 247, 1884, 6, 2572, 275, 25662, 17575, 15, 2064, 369, 2217, 281, 3324, 253, 7355, 281, 247, 7503, 1462, 23350, 13, 13455, 272, 253, 6495, 27675, 323, 1107, 15, 187, 187, 42, 1053, 457, 85, 1333, 326, 253, 17940, 7466, 762, 38140, 574, 642, 7328, 800, 1055, 275, 253, 6495, 27675, 390, 326, 253, 17940, 7466, 762, 6729, 275, 253, 11573, 27675, 574, 642, 7328, 800, 1055, 13, 533, 368, 476, 457, 85, 5276, 326, 22669, 3646, 310, 19437, 816, 407, 40935, 441, 326, 38734, 10490, 281, 5467, 313, 284, 604, 352, 497, 247, 958, 10, 326, 253, 4831, 323, 2583, 310, 4122, 39188, 281, 2544, 275, 253, 2281, 273, 1600, 15, 380, 3064, 875, 253, 5233, 7355, 432, 253, 6495, 27675, 672, 4343, 1669, 253, 5328, 2629, 285, 253, 5075, 7355, 432, 253, 11573, 27675, 310, 326, 6108, 253, 5328, 2629, 574, 271, 8993, 1055, 327, 4376, 14, 5251, 12656, 13, 1223, 22669, 7466, 1309, 253, 11573, 27675, 369, 20023, 342, 6843, 718, 47879, 407, 253, 22669, 9061, 326, 253, 374, 6, 15631, 2303, 1108, 275, 253, 5170, 3884, 13, 387, 667, 2281, 1905, 369, 13, 285, 651, 11654, 625, 3464, 13, 20075, 285, 828, 10966, 494, 15, 187, 187, 688, 521, 6323, 5311, 1501, 5171, 611, 2371, 1342, 12491, 619, 4116, 281, 6018, 37889, 457, 84, 16555, 380, 6495, 7335, 1765, 273, 17437, 15, 496, 12930, 253, 12546, 414, 273, 253, 17437, 1499, 1765, 13, 6018, 37889, 6283, 2429, 253, 12147, 273, 253, 17437, 1499, 1765, 342, 253, 18471, 14, 1797, 9037, 13, 15806, 326, 253, 4376, 10343, 275, 18471, 14, 1797, 369, 273, 247, 2074, 9777, 281, 326, 273, 17437, 15, 5490, 13629, 13, 275, 521, 1984, 327, 253, 6495, 383, 27675, 13, 8219, 326, 253, 6495, 383, 27675, 369, 594, 16383, 13, 984, 13, 275, 4499, 281, 253, 6495, 27675, 13, 627, 369, 642, 3177, 407, 253, 2208, 275, 18471, 14, 1797, 281, 36100, 253, 8230, 15, 7820, 13, 253, 9136, 326, 320, 816, 6225, 896, 285, 1339, 253, 22144, 1379, 253, 17134, 2252, 15, 187, 187, 9499, 37889, 574, 247, 1027, 1379, 327, 253, 3064, 875, 253, 6495, 383, 27675, 285, 253, 6495, 27675, 27, 187, 187, 6407, 273, 512, 13, 253, 9559, 7217, 273, 253, 1499, 1765, 310, 281, 320, 8344, 15, 496, 253, 1264, 4283, 9787, 4343, 273, 253, 1533, 1128, 783, 1986, 2077, 13, 6495, 9643, 13, 285, 6176, 1128, 740, 13, 933, 13, 933, 5820, 1462, 27473, 15, 1707, 310, 28438, 271, 1774, 4491, 9825, 22915, 2217, 11528, 281, 1056, 352, 5645, 1128, 4609, 310, 253, 1071, 273, 4780, 15, 2058, 253, 1072, 673, 13, 275, 253, 4343, 273, 3625, 3275, 253, 3453, 273, 15067, 285, 273, 21047, 310, 10156, 13, 275, 253, 1083, 273, 2761, 1046, 1774, 31142, 13, 387, 247, 4376, 534, 13, 323, 1142, 390, 323, 253, 5020, 273, 18014, 13, 1057, 417, 3835, 697, 2105, 15, 496, 33531, 13, 672, 7911, 6497, 347, 11306, 13, 253, 2965, 369, 432, 247, 25014, 1268, 387, 534, 18014, 497, 2403, 10969, 16256, 28, 285, 627, 310, 642, 1650, 275, 4980, 2892, 273, 594, 1270, 285, 5233, 247, 2965, 273, 7911, 432, 247, 2622, 4677, 347, 556, 5866, 275, 253, 2469, 807, 15, 7757, 253, 9777, 273, 253, 41786, 15, 187, 187, 688, 48858, 752, 2427, 3430, 275, 253, 6495, 27675, 13, 6018, 37889, 8127, 13, 2167, 417, 7094, 13, 9829, 253, 954, 1774, 2847, 273, 253, 41786, 13, 253, 24540, 273, 5328, 4269, 407, 253, 3177, 281, 15042, 271, 5213, 5328, 2629, 1293, 247, 2097, 407, 534, 281, 1453, 253, 22669, 4831, 323, 5328, 273, 253, 1533, 457, 84, 4275, 10907, 1905, 954, 417, 49186, 13, 253, 24812, 6022, 273, 6181, 15, 6018, 37889, 943, 452, 5087, 625, 4116, 281, 9221, 85, 5292, 285, 16211, 293, 685, 344, 858, 15, 1292, 6018, 37889, 369, 8839, 327, 2303, 275, 15571, 2139, 253, 1533, 625, 4354, 19360, 285, 12372, 432, 247, 3387, 6, 809, 4004, 275, 18471, 14, 1797, 685, 352, 369, 2104, 281, 513, 275, 29063, 14, 1610, 15, 187, 187, 19174, 254, 35382, 55, 26604, 6289, 479, 281, 247, 2278, 3929, 407, 5119, 1879, 360, 275, 253, 1655, 2523, 273, 253, 14847, 43562, 273, 380, 6304, 4079, 1615, 13187, 21994, 2721, 13, 271, 5054, 2892, 273, 253, 3973, 3645, 3660, 13, 697, 31433, 13, 285, 253, 6054, 273, 3968, 347, 253, 806, 4156, 2221, 9177, 1580, 253, 8370, 13958, 15 ]	— 10 years before the start of the Great Depression in 1919, when they independently warned that going back on the gold standard at the post-World War I price level (in terms of gold) — about twice the pre-War price level — would cause a disastrous deflation unless the world’s monetary authorities took concerted action to reduce the international monetary demand for gold as countries went back on the gold standard to a level consistent with the elevated post-War price level. The Genoa Monetary Conference of 1922, inspired by the work of Hawtrey and Cassel, resulted in an agreement (unfortunately voluntary and non-binding) that, as countries returned to the gold standard, they would neither reintroduce gold coinage nor keep their monetary reserves in the form of physical gold, but instead would hold reserves in dollar or (once the gold convertibility of sterling was restored) pound-denominated assets. (Ron Batchelder and I have a paper discussing the work of Hawtrey and Casssel on the Great Depression; Doug Irwin has a paper discussing Cassel.) After the short, but fierce, deflation of 1920-21 (see here and here), when the US (about the only country in the world then on the gold standard) led the world in reducing the price level by about a third, but still about two-thirds higher than the pre-War price level, the Genoa system worked moderately well until 1928 when the Bank of France, totally defying the Genoa Agreement, launched its insane policy of converting its monetary reserves into physical gold. As long as the US was prepared to accommodate the insane French gold-lust by permitting a sufficient efflux of gold from its own immense holdings, the Genoa system continued to function. But in late 1928 and 1929, the Fed, responding to domestic fears about a possible stock-market bubble, kept raising interest rates to levels not seen since the deflationary disaster of 1920-21. And sure enough, a 6.5% discount rate (just shy of the calamitous 7% rate set in 1920) reversed the flow of gold out of the US, and soon the US was accumulating gold almost as rapidly as the insane Bank of France was. This was exactly the scenario against which Hawtrey and Cassel had been warning since 1919. They saw it happening, and watched in horror while their warnings were disregarded as virtually the whole world plunged blindly into a deflationary abyss. Keynes had some inkling of what was going on – he was an old friend and admirer of Hawtrey and had considerable regard for Cassel – but, for reasons I don’t really understand, Keynes was intent on explaining the downturn in terms of his own evolving theoretical vision of how the economy works, even though just about everything that was happening had already been foreseen by Hawtrey and Cassel. More than a quarter of a century after the fact, and after the Keynesian Revolution in macroeconomics was well established, along came Friedman, woefully ignorant of pre-Keynesian monetary theory, but determined to show that the Keynesian explanation for the Great Depression was wrong and unnecessary. So Friedman came up with his own explanation of the Great Depression that did not even begin until December 1930 when the Fed allowed the Bank of United States to fail, triggering, in Friedman’s telling, a wave of bank failures that caused the US money supply to decline by a third by 1933. Rather than see the Great Depression as a global phenomenon caused by a massive increase in the world’s monetary demand for gold, Friedman portrayed it as a largely domestic phenomenon, though somehow linked to contemporaneous downturns elsewhere, for which the primary explanation was the Fed’s passivity in the face of contagious bank failures. Friedman, mistaking the epiphenomenon for the phenomenon itself, ignorantly disregarded the monetary theory of the Great Depression that had already been worked out by Hawtrey and Cassel and substituted in its place a simplistic, dumbed-down version of the quantity theory. So Friedman reinvented the wheel, but did a really miserable job of it. A. C. Pigou, Alfred Marshall’s student and successor at Cambridge, was a brilliant and prolific economic theorist in his own right. In his modesty and reverence for his teacher, Pigou was given to say “It’s all in Marshall.” When it comes to explaining the Great Depression, one might say as well “it’s all in Hawtrey.” So I agree that Delong is totally justified in criticizing Friedman and his followers for giving such a silly explanation of the Great Depression, as if it were, for all intents and purposes, made in the US, and as if the Great Depression didn’t really start until 1931. But the problem with Friedman is not, as Delong suggests, that he distracted us from the superior insights of Keynes and Minsky into the causes of the Great Depression. The problem is that Friedman botched the monetary theory, even though the monetary theory had already been worked out for him if only he had bothered to read it. But Friedman’s interest in the history of monetary theory did not extend very far, if at all, beyond an overrated book by his teacher Lloyd Mints A History of Banking Theory. As for whether fiscal expansion called for by Keynes was necessary to end the Great Depression, we do know that the key factor explaining recovery from the Great Depression was leaving the gold standard. And the most important example of the importance of leaving the gold standard is the remarkable explosion of output in the US beginning in April 1933 (surely before expansionary fiscal policy could take effect) following the suspension of the gold standard by FDR and an effective 40% devaluation of the dollar in terms of gold. Between April and July 1933, industrial production in the US increased by 70%, stock prices nearly doubled, employment rose by 25%, while wholesale prices rose by 14%. All that is directly attributable to FDR’s decision to take the US off gold, and devalue the dollar (see here). Unfortunately, in July 1933, FDR snatched defeat from the jaws of victory (or depression from the jaws of recovery) by starting the National Recovery Administration, whose stated goal was (OMG!) to raise prices by cartelizing industries and restricting output, while imposing a 30% increase in nominal wages. That was enough to bring the recovery to a virtual standstill, prolonging the Great Depression for years. I don’t say that the fiscal expansion under FDR had no stimulative effect in the Great Depression or that the fiscal expansion under Obama in the Little Depression had no stimulative effect, but you can’t prove that monetary policy is useless just by reminding us that Friedman liked to assume (as if it were a fact) that the demand for money is highly insensitive to changes in the rate of interest. The difference between the rapid recovery from the Great Depression when countries left the gold standard and the weak recovery from the Little Depression is that leaving the gold standard had an immediate effect on price-level expectations, while monetary expansion during the Little Depression was undertaken with explicit assurances by the monetary authorities that the 2% inflation target – in the upper direction, at any rate — was, and would forever more remain, sacred and inviolable. In his latest blog post Paul Krugman drew my attention to Keynes’s essay The Great Slump of 1930. In describing the enormity of the 1930 slump, Keynes properly compared the severity of the 1930 slump with the 1920-21 episode, noting that the price decline in 1920-21 was of a similar magnitude to that of 1930. James Grant, in his book on the Greatest Depression, argues that the Greatest Depression was so outstanding, because, in contrast to the Great Depression, there was no attempt by the government in 1920-21 to cushion the blow. Instead, the powers that be just stood back and let the devil take the hindmost. Keynes had a different take on the difference between the Greatest Depression and the Great Depression: First of all, the extreme violence of the slump is to be noticed. In the three leading industrial countries of the world—the United States, Great Britain, and Germany—10,000,000 workers stand idle. There is scarcely an important industry anywhere earning enough profit to make it expand—which is the test of progress. At the same time, in the countries of primary production the output of mining and of agriculture is selling, in the case of almost every important commodity, at a price which, for many or for the majority of producers, does not cover its cost. In 1921, when prices fell as heavily, the fall was from a boom level at which producers were making abnormal profits; and there is no example in modern history of so great and rapid a fall of prices from a normal figure as has occurred in the past year. Hence the magnitude of the catastrophe. In diagnosing what went wrong in the Great Depression, Keynes largely, though not entirely, missed the most important cause of the catastrophe, the appreciation of gold caused by the attempt to restore an international gold standard without a means by which to control the monetary demand for gold of the world’s central banks — most notoriously, the insane Bank of France. Keynes should have paid more attention to Hawtrey and Cassel than he did. But Keynes was absolutely on target in explaining why the world more easily absorbed and recovered from a 40% deflation in 1920-21 than it was able to do in 1929-33. Commenter TravisV kindly referred me to a review article by David Frum in the current issue of the Atlantic Monthly of The Delugeby Adam Tooze, an economic history of the First World War, its aftermath, and the rise of America as the first global superpower since the Roman Empire.
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Then there is a subset $S_t\subset S$ with $\rm{vol}(S_t)$$\geq\varsigma/2$ for which a sweep over $\hat{\rho}_{t,u}$ for any vertex $u\in S_t$ with 1. $t={\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$ and 2. $\Phi_{\varsigma}(\hat{\rho}_{t,u})^2 \leq 4/t\log(2)$\[assumption:sweepcheeg\] finds a set with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. Let $u$ be a vertex in $S_t$ as described in the theorem statement. Using the inequalities (\[eq:approxineq\]), we can bound the local Cheeger ratio by a sweep over $\hat{\rho}_{t,u}$: $$e^{-t{\Phi^(S)}} \leq \frac{2}{1-\epsilon}(\sqrt{\varsigma}e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4}+\epsilon s)$$ which implies $$e^{-t{\Phi^(S)}} \leq e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4} \Big(\frac{2\sqrt{\varsigma}}{1-\epsilon} + \epsilon s e^{t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4}\Big),$$ and by the assumption \[assumption:sweepcheeg\], we have $$\begin{aligned} e^{-t{\Phi^(S)}} &\leq e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4} \Big(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s\Big)\\ {\Phi^(S)}&\geq \frac{\Phi_{\varsigma}(\hat{\rho}_{t,u})^2}{4} - \frac{\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}{t}.\end{aligned}$$ Let $x=\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)$. Then, $$\Phi_{\varsigma}(\rho_{t,f_S})^2 \leq 4{\Phi^(S)}+ 4x/t.$$ Since ${\Phi^(S)}\leq \Phi(S) \leq \phi$ and $t = \phi^{-1}x$, it follows that $\Phi_{\varsigma}(\hat{\rho}_{t,u}) \leq \sqrt{8\phi}$. In particular, a sweep over $\hat{\rho}_{t,u}$ finds a cut with Cheeger ratio $O(\sqrt{\phi})$ as long as $u$ is contained in $S_t$. We are now prepared to give our algorithm for finding cuts locally with heat kernel pagerank. The algorithm takes as input a starting vertex $u$, a desired volume $\varsigma$ for the cut set, and a target Cheeger ratio $\phi$ for the cut set. Then, to find a set achieving a minimum $\varsigma$-local Cheeger ratio, we perform a sweep over an approximate heat kernel pagerank vector with the starting vertex as a seed. input: a graph $G$, a vertex $u$, target cluster size $s$, target cluster volume $\varsigma \leq {\textmd{vol}}(G)/4$, target Cheeger ratio $\phi$, error parameter $\epsilon$.\ output: a set $T$ with $\varsigma/2 \leq {\textmd{vol}}(T) \leq 2\varsigma$, $\Phi(T) \leq \sqrt{8\phi}$.\ $t \gets {\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$ $\hat{\rho} \gets {\texttt{ApproxHKPRseed($G,t,u,\epsilon$)}}$\[line:hkpr\] sort the vertices of $G$ in the support of $\hat{\rho}$ according to the ranking $\hat{\rho}[v]/d_{v}$\[line:sort\] \[line:sweep\] $S_j = \bigcup_{i\leq j}v_i$ \[line:volume\] output `NO CUT FOUND`, break \[line:checks\] output $S_j$ output `NO CUT FOUND` [\[thm:localpart\]]{} Let $G$ be a graph which contains a subset $S$ of volume at most $\rm{vol}(G)/4$ and Cheeger ratio bounded by $\phi$. Further, assume that $u$ is contained in the set $S_t\subseteq S$ as defined in Theorem \[thm:main\]. Then [`ClusterHKPR(G,u,s,\varsigma,\phi,\epsilon)`]{}outputs a cutset $T$ with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. The running time is the same as that of [`ApproxHKPRseed`]{}. Since it is given that $u\in S_t$ for $t={\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$, and by the assumptions on $G$ and $S$, Theorem \[thm:main\] states that a sweep over the approximate heat kernel pagerank vector $\hat{\rho}$ will find a set with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. The checks performed in line \[line:checks\] of the algorithm discover such a set. The computational work reduces to the main procedures of computing the heat kernel pagerank vector in line \[line:hkpr\] and performing a sweep over the vector in line \[line:sweep\]. Performing a sweep involves sorting the support of the vector (line \[line:sort\]) and calculating the conductance of segments. From the guarantees of an $\epsilon$-approximate heat kernel pagerank vector, any vertex with average probability less than $\epsilon$ will be excluded from the support. Then the volume of a vector $\hat{\rho}$ output in line \[line:hkpr\] is $O(\epsilon^{-1})$, and performing a sweep over $\hat{\rho}$ can be done in $O(\epsilon^{-1}\log(\epsilon^{-1}))$ time. The algorithm is therefore dominated by the time to compute a heat kernel pagerank vector, and the total running time is ${O\big(\frac{\log(\epsilon^{-1})\log n}{\epsilon^3\log\log(\epsilon^{-1})}\big)}$. Ranking Vertices with Approximate Heat Kernel Pagerank {#sec:rankings} ====================================================== The backbone procedure of the local clustering algorithm is the sweep: ranking the vertices of the graph according to their approximate heat kernel pagerank values, and then testing the quality of the cluster obtained by adding vertices one at a time in the order of this ranking. To this end, in this section we compare the rankings of vertices obtained using exact heat kernel pagerank vectors with approximate heat kernel pagerank vectors. Specifically, we consider how accuracy changes as the upper bound of random walk lengths, $K$, vary. In the following experiments, we approximate heat kernel pagerank vectors by sampling random walks of length $\min\{k, K\}$, where $k$ is chosen with probability $p_k = e^{-t}\frac{t^k}{k!}$. We test the values computed with different values of $K$. Since the expected value of a random walk length $k$ chosen with probability $p_k = e^{-t}\frac{t^k}{k!}$ is $t$, we set $K$ to range from $1$ to approximately $t$ for a specified value of $t$. In each trial, for a given graph, seed vertex, and value of $t$, we compute an exact heat kernel pagerank vector $\rho_{t,u}$ and an approximate heat kernel pagerank vector $\hat{\rho}_{t,u}$ using [`ApproxHKPRseed`]{} but limiting the length of random walks to $K$ for various $K$ as described above. We then measure how similar the vectors are in two ways. First, we compare the vector values computed. Second, we compare the rankings obtained with each vector. The following are the measures used: 1. Comparing vector values. We measure the error of the approximate vector $\hat{\rho}_{t,u}$ by examining the values computed for each vertex and comparing to an exact vector $\rho_{t,u}$. We use the following measures: - Average $L_1$ error: The average absolute error over all vertices of the graph, $$\label{eq:measure-l1err} \mbox{average $L_1$ error } := \frac{1}{n}\sum_{i=1}^n \|\rho_{t,u}(v_i)-\hat{\rho}_{t,u}(v_i)\|.$$ - $\epsilon$-error: The accumulated error in excess of an $\epsilon$-approximation (see Definition \[def:eps-approx\]), $$\begin{aligned} \mbox{$\epsilon$-error } := &\sum_{v\in V, \hat{\
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187, 187, 20576, 273, 209, 187, 5, 2420, 1168, 37380, 2618, 2073, 34590, 64, 301, 47007, 48454, 2073, 13994, 398, 64, 2420, 5137, 535, 6892, 398, 16908, 1108, 253, 2159, 3662, 310, 309, 1053, 457, 85, 309, 3289, 3253, 598, 13, 1527, 598, 253, 23700, 285, 840, 11585, 42842, 281, 253, 1263, 281, 4446, 3253, 432, 253, 5890, 15 ]	While Taylor has now broken records in the pop genre, Little Big Town insists she hasn’t completely parted with her country roots. “She’s a Nashville songwriter,” Little Big Town‘s Karen Fairchild told USA Today. “When you write a song like “Better Man” top to bottom on your own with your acoustic guitar, that’s Nashville. She’s a storyteller. She loves country music. Her last record was more poppy but who knows? Taylor can do anything she wants to. And she will forever be a Nashville girl.”Q: How to extract text data in a table created in a docx document I would like to extract text from docx document, I come up with a script extracting text from docx document but I noticed that some document have table and the script do not work on them, How can I improve the above script : import glob import os import docx with open('your_file.txt', 'w') as f: for directory in glob.glob('fi'): for filename in glob.glob(os.path.join(directory, "")): if filename.endswith((".docx", ".doc")): document = docx.Document(filename) for paragraph in document.paragraphs: if paragraph.text: #docText.append(paragraph.text) f.write("%s\n" % paragraph.text) docx with table A: Try using python-docx module instead pip install python-docx import docx doc = docx.Document("document.docx") for table in doc.tables: for row in table.rows: for cell in row.cells: print(cell.text) Promoting Health and Behavioral Health Equity in California. Behavioral health disparities are not usually considered part of the same system of health disparities. However, the California Department of Public Health focused its health equity strategies on reducing behavioral health disparities through its California Statewide Plan to Promote Health and Mental Health Equity. This statewide plan was developed through a community-wide stakeholder engagement and outreach process. In addition, the California Reducing Disparities Project is a prevention and early intervention effort to reduce mental health disparities in underserved populations. This strategic plan represents the voice of several racial/ethnic communities, such as African American, Asian and Pacific Islander, Latino, Native American, as well as lesbian, gay, bisexual, transgender, and queer and questioning communities in California, through 5 strategic planning workgroups. The workgroups were composed of a broad range of stakeholders, including community leaders, mental health care providers, consumer and family members, individuals with lived experience, and academia. This case example highlights the various efforts of California's Office of Health Equity in eliminating behavioral health disparities and promoting mental health equity, as well as discusses the unique statutory and regulatory role of the Office of Health Equity's deputy director.@import "~styles/variables"; thead { font-size: 14px; letter-spacing: 0.2px; color: $chef-primary-dark; } th { text-align: left; padding: 0px; } tbody > .detail-row { padding-top: 0px; padding-bottom: 15px; } chef-table-new { .controls { text-align: right; } a { cursor: pointer; text-decoration: underline; } } chef-loading-spinner { display: block; margin: 100px auto; width: 100px; z-index: 199; } Q: Laravel 7.0 MySQL SQLSTATE[HY000]: General error: 1824 Failed to open the referenced table System Info: OS: Ubuntu 19.10 Laravel Version: 7.0 PHP Version: 7.3.11-0ubuntu0.19.10.4 MySQL Version: mysql Ver 8.0.19-0ubuntu0.19.10.3 for Linux on x86_64 ((Ubuntu)) I am building a small Laravel application and am having an issue with MySQL and relationships. When I try to run my migrations, this is the error I get: SQLSTATE[HY000]: General error: 1824 Failed to open the referenced table 'customers_table' (SQL: alter table `customer_contacts` add constraint `customer_contacts_customer_id_foreign` foreign key (`customer_id`) references `customers_table` (`id`)) And these are the two migration files in question. customer table and migration: <?php use Illuminate\Database\Migrations\Migration; use Illuminate\Database\Schema\Blueprint; use Illuminate\Support\Facades\Schema; class CreateCustomersTable extends Migration { /** * Run the migrations. * * @return void / public function up() { Schema::create('customers', function (Blueprint $table) { $table->id(); $table->string('company_name', 50); $table->string('phone_number', 20)->nullable(); $table->string('fax_number', 20)->nullable(); $table->string('address_line_1', 75)->nullable(); $table->string('address_line_2', 75)->nullable(); $table->string('city', 75)->nullable(); $table->string('state', 30)->nullable(); $table->string('zip', 11)->nullable(); $table->string('industry', 100)->nullable(); $table->text('notes')->nullable(); $table->timestamps(); }); } /* * Reverse the migrations. * * @return void / public function down() { Schema::dropIfExists('customers'); } } And the customer_contacts table and migration: <?php use Illuminate\Database\Migrations\Migration; use Illuminate\Database\Schema\Blueprint; use Illuminate\Support\Facades\Schema; class CreateCustomerContactsTable extends Migration { /* * Run the migrations. * * @return void / public function up() { Schema::create('customer_contacts', function (Blueprint $table) { $table->id(); $table->foreignId('customer_id')->constrained('customers_table'); $table->string('name', 50); $table->string('title', 50); $table->string('project', 50); $table->string('email', 50); $table->string('mobile_phone', 20); $table->string('work_phone', 20); $table->timestamps(); }); } /* * Reverse the migrations. * * @return void */ public function down() { Schema::dropIfExists('customer_contacts'); } } And this is the relevant section from my database.php file: ... 'mysql' => [ 'driver' => 'mysql', 'url' => env('DATABASE_URL'), 'host' => env('DB_HOST', '127.0.0.1'), 'port' => env('DB_PORT', '3306'), 'database' => env('DB_DATABASE', 'forge'), 'username' => env('DB_USERNAME', 'forge'), 'password' => env('DB_PASSWORD', ''), 'unix_socket' => env('DB_SOCKET', ''), 'charset' => 'utf8mb4', 'collation' => 'utf8mb4_unicode_ci', 'prefix' => '', 'prefix_indexes' => true, 'strict' => true, 'engine' => 'InnoDB', 'options' => extension_loaded('pdo_mysql') ? array_filter([ PDO::MYSQL_ATTR_SSL_CA => env('MYSQL_ATTR_SSL_CA'), ]) : [], ], ... I tried changing my database to SQLite to see if I get the same error and I do not, only MySQL creates this error. A: Use $table->foreignId('customer_id')->constrained('customers') Instead of $table->foreignId('customer_id')->constrained('customers_table'); Cheers Dave – the short answer is I don’t I fire everything up, open up the aperture and then retire indoors to the study to drive everything from the warm.
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too, David. I'm out of here." Sasha was sick of all of them. She'd seen where the bullets were buried and that was all she needed to know. She turned on her heel and started up the hill, breaking into a jog. "Sasha!" Julian called after her. "Catch you later?" "Forget it!" Sasha called back, charging up the hill. ## CHAPTER 14 ■ ## Julian Browne Julian's mother entered the room with a tray holding a bowl of popcorn and root beer floats. She had gone to a lot of trouble, but all he could think about was Sasha. It was already past eight o'clock at night, and Sasha hadn't been home since they buried the gun and bullets. He'd been watching the house, and her room was completely dark. The only lights on were in Bonnie and Clyde's suite and the family room downstairs, which they kept on when Sasha wasn't home. Julian didn't know where she was, and it was driving him crazy. "Movie night!" his mother said, setting down the tray. "How much fun is this?" "Fun." Julian smiled, hoping it looked convincing. "Real butter and everything?" "Nothing but the best for my baby!" His mother put a napkin in front of him, then a root beer float with a special long spoon. His parents used to entertain all the time, and his mother had shrimp forks, mother-of-pearl caviar spoons, and cake knives. She even had special ice cream dishes, gravy boats, soup tureens, and ramekins; Julian knew the names because she took the time to educate him. Now the only person she was entertaining was him. "I just love that we get to spend this time together, truly quality time." "Right." Julian glanced out the window, keeping an eye on Sasha's house. Their family room was cavernous with brown leather sectionals arranged opposite the fireplace and entertainment center, and on the left side of the room, they had huge Palladian windows. It gave Julian a great view of the street, and from this angle, Sasha's house. The light over her front door was on. He sensed she was punishing him for what happened with Allie. "Have some root beer float. It's going to melt." "Good point." Julian picked up the spoon and slurped some root beer float, which tasted absolutely delicious. "This is perfect, Mom. Thanks." "I love that you still drink it with the spoon. You used to do that when you were little." "This spoon seemed bigger then." "I'm sure." His mother grinned broadly, so excited on these weeknights, when it was _her night_ as opposed to _his father's night_ , since Julian went to his dad's house on alternating Tuesdays and Thursdays, depending on if he had been there the weekend. His mother always tried to plan something special for them, which they had never done when his father lived at home. He secretly wondered if she felt she had to, in order to win him over in the battle of who he liked better, mommy versus daddy. Of course she won hands-down, but he could never convince her of that and he understood why. His father offered motorboats, blondes, and no adult supervision. Because his father wasn't an adult. "Which movie do you want to watch first?" His mother held up the two VHS tapes, her pick, _You've Got Mail,_ and his pick, _The Big Lebowski_. "We can watch yours first, Mom." "No, we can do yours." "Please, you love chick flicks." Julian glanced out the window, but the Barrow house was still dark and quiet. One of their neighbors was walking his malamute, but nobody else was on the street. "No, we watched mine first last time, remember? I love a double feature!" "What's a double feature?" "Oh my, I'm dating myself. Oh well, somebody has to these days!" His mother laughed as she crossed the room, slid the tape into the VHS player, and picked up the remote, hitting a few buttons to get the tape running. She eyed _The Big Lebowski_ box. "What's this about again?" "It's great, I love it." "Wait, you saw it already?" "Yeah, I told you at the store." "I didn't hear you. Don't tell me my hearing's going now, too." "I saw it with Dad." Julian didn't add that his father hadn't seen the movie with him, just dropped him off. "It doesn't matter. I want to see it again." "I didn't want you to have to sit through something you saw already." "But I love it. I want to." "Okay." His mother returned her attention to the movie, which was starting. "So is that man the big Lebowski? He wears a bathrobe to the grocery store?" "Yeah, he's a stoner." His mother frowned. "You mean he smokes dope?" "Weed." "We called it dope, in my day." "People call it weed now." Julian didn't explain that his father called it weed, even though he was from the same day. Nor did he tell her that his father smoked weed on the boat. "But _you_ would never smoke dope, er, weed." His mother shot him a look. "No, I wouldn't." Julian didn't say that he'd tried weed for the first time when his father gave him some on a trip to Cape May. Julian had liked smoking with his dad and the blonde _du jour_. His father let him have beer, too, but Julian took it easy because beer made him fart, which would not be cool. "Don't even experiment with it, okay?" His mother sat down on the couch. "They tell you that in school, right?" "Yeah, in D.A.R.E., since middle school." Julian didn't add that the weed-and-beer combination made him throw up over the side of the boat. His father had laughed, and the blonde hadn't known what to do, though his mom would have brought him a ginger ale. His mother frowned at the TV screen. "Does this glorify drug use?" "It's a comedy; he's funny." Julian was so preoccupied he couldn't think straight. Sasha still wasn't home. She dated seniors like Jake Myers, Malcolm Hobb-Jacobs, and Zachary Pearlstein, major competition. Julian knew their cars, so when one of them dropped her off, he would know who. "Jeff Bridges used to be so handsome! He really let himself go for this role!" "He drinks White Russians. That's his thing. He drinks them all the time. He calls them his 'beverage.'" Julian didn't remind his mother that she had drunk plenty in her entertaining days, and she fell silent, watching the movie with growing disapproval. "There are a lot of f-words in this movie, honey." His mother shook her head, clucking. "Why would your father take you to a movie that's so inappropriate?" "I asked." "It's not on you, it's on him. What's it rated?" "Don't worry about it, Mom." Julian rolled his eyes, restless. This was going to end up with his mother calling her lawyer, then her lawyer calling his father's lawyer, who would talk to his father, which sucked. The movie went on without Julian seeing it, thinking of Sasha. "Oh no, who are those guys?" "Bad guys." "Why are they hurting him?" "They have him mixed up with another Lebowski. He's Jeffrey Lebowski, the Dude. They think he's a millionaire." "Wait, are they _peeing on the rug_?" His mother threw up her manicured hands. "Julian, how can you like this movie? It doesn't make any sense." "Let's watch yours then, okay?" Julian couldn't enjoy it anyway. Where the hell was Sasha? Who was she with? Was she having sex with one of those seniors? Seniors got it all the time, didn't they? They expected it! It made Julian crazy because he had loved her for forever. "You mean stop watching it? Are you sure you don't mind?" His mother pouted prettily, like the cheerleader she'd been, and Julian realized that beautiful women always got what they wanted. Sasha sure did. "I saw it already. See, it turned out fine." "You sure?" "Please put on your chick flick, Mom." "Don't call it a chick flick. It's a love story. Men can enjoy love stories, don't you think?" "Yes," Julian said, ironically in the circumstances. Suddenly he noticed a car pulling up in front of Sasha's house. Zachary Pearlstein's red BMW 325. "Here we go! Oh, I love Tom Hanks. Isn't he just the best? I think he's so cute
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When it came, no lie, my kids fought daily over who would get to read it on the bus, and how long each was allowed to have it, and whether or not the others were taking good care of it during their turns. Even the neighbor boys were in awe of this treasure. It didn't take me long to realize what I needed to do. I needed to call LEGO. After I explained that just one was not going to do it for us, I signed ALL THREE of my boys up to receive their very OWN catalog. They have anxiously anticipated them from that moment onward. Like I said, they "read" them on the bus. They read them in the car. They read them while we're waiting--just about anywhere. They read them in their bedrooms, and at the kitchen counter. They read them in the bathroom and even under blankets with a flashlight. Yes, boys, I know about that. So order. It's FREE! The boys in your life will think you rock. And that doesn't happen nearly enough! We've not tried this one, but LEGO also has a program called BrickMaster. It costs $39.99 and comes with six BrickMaster Edition LEGO magazines (one every two months), Six surprise LEGO toys (mailed out one every two months), two LEGO Shop at Home Coupons, and a free LEGOLAND California Admission ticket. If any of you have tried this, I'd love to hear your thoughts on it! 11 comments: You also need to sign the boys up for the Lego and Bionicle MAGAZINES! My son thinks they are the greatest things ever produced, and they both are completely free - he has been getting them for a few years now! Have fun!! Augh -- I tried to do it, and saw that it asked about age ranges. I didn't read and just assumed they were asking the age of my kids. Oops -- must have been asking my age, because now it won't let me ask for a catalog. D'oh! We signed up for the magazine a few months ago and my son kept asking whether or not the magazine had come in the mail and if it didn't he thought I ought to call them and remind them or see what was happening - he was so eager to get it. And then - just b/c of the timing of our subscription we got 2 or 3 in a very short time - so he was happy. All three of my kids loved LEGOS when they were younger. And LEGO land was the ultimate play place for them! Now that they're older, I'm just waiting for them to have kids so I can start stocking up on LEGOS again! We love Lego mags at our house! In fact, I have to hide them so they don't discover them until AFTER homework is done. I've also been thinking about the Brickmaster thing. My guys have told me it would be "hard to share," so I'm looking at 2 - which means $80 - not that it doesn't seem worth it. I'm thinking Brickmaster may be birthday presents in 2009. "Let's raise our children up in prayer. . . . . . as we raise them up to serve our God!"Here, you'll find food for thought, helpful tips, DIY tricks, and stories from everyday life, all posted with the hope of encouraging and strengthening families in every aspect of life. Followers Great Resources Product ReviewsDo you have a family friendly product you think my readers would like? I give honest and informative reviews of family friendly products. Please feel free to drop me an email and we can discuss the possiblity of sharing your product with my readers! Be sure to include "review" in the subject line.5 tablespoons (1/3rd cup) bleach per gallon of water OR OR 4 teaspoons bleach per quart of water Follow manufacturer’s instructions for application and proper ventilation. Check to ensure the product is not past its expiration date. Never mix household bleach with ammonia or any other cleanser. Unexpired household bleach will be effective against coronaviruses when properly diluted.Cannabis industry exploding with growth here, says top pot exec The cannabis business is growing like a weed, even as pot stocks see wild swings. With Smoke Wallin, Vertical Companies, CNBC's Scott Wapner and the Fast Money traders, Pete Najarian, Tim Seymour, Karen Finerman and Guy Adami.Shifts of system performance and microbial community structure in a constructed wetland after exposing silver nanoparticles. The increasing utilization of silver nanoparticles (Ag NPs) in industry and commerce inevitably raises its release into wastewater. In this work, effects of Ag NPs on system performance and microbial community along the way of a vertical flow constructed wetland (VFCW) were investigated, along with the removal and fate of Ag NPs within the system. Results showed that the performance of control wetland kept stable during the experimental period, and the top substrate layer (soil layer) of wetland could remove most of pollutants in the influent. The study also suggested that addition of Ag NPs did not significantly affect organic matters removal. However, adverse effects were observed on the nitrogen and phosphorus removal. Removal efficiencies of TN, NH4+-N and TP approximately obviously reduced by approximately 10.10%, 8.42% and 28.35% respectively in contrast to before dosing after exposing 100 μg/L Ag NPs for 94 d, while the no dosing wetland with the stable performance. It was found that Ag NPs accumulated in the upper soil layer more than in the lower soil layer, and Ag NPs could enter into the plant tissues. After continuous input of Ag NPs, removal efficiency of Ag NPs was measured as 95.72%, which showed that the CW could effectively remove Ag NPs from the wastewater. The high-throughput sequencing results revealed that Ag NPs caused the shifts in microbial community structures and changed the relative abundances of key functional bacteria, which finally resulted in a lower efficiency of biological nitrogen and phosphorus removal.John Vorster Square in central Johannesburg is a building as cold and formidable as the man it was named after: South Africa's prime minister from 1966 to 1978. Created as a detention centre for mainly political prisoners, the forbidding grey-and-blue, 10-storey cement building, now known as the Johannesburg Central Police Station, was described in 1971 as the "last word in security" by the liberal South African newspaper, the Rand Daily Mail. In his book, Timol: A Quest for Justice, Imtiaz Cajee, nephew of anti-apartheid activist Ahmed Timol, wrote of the "paranoia of its turnstiles clamping together like metal teeth". To Cajee, whose uncle died at John Vorster Square, it was "the ultimate symbol of the bureaucratisation of fear and horror under apartheid". Former Minister of Health and of Public Enterprises Barbara Hogan, who - as the first South African woman to be found guilty of high treason - was detained there, described it as an "iconic institution" that symbolised "the reign of the mad forces". The ninth and 10th floors of the building were where the headquarters of the Security Branch was located. They could be accessed by two special lifts that ran straight from the basement to the headquarters. The Security Branch offices contained special soundproof rooms. Direct-line telephones were connected to the Security Branch headquarters in the capital, Pretoria. The detainee cells were on the lower floors. The Johannesburg Central Police Station, formerly known as John Vorster Square, was the site of the death of political activist and detainee Ahmed Timol [GULSHAN KHAN/AFP] Detention without trial John Vorster Square was one of the architectural symbols of apartheid. But the real pillars of apartheid were the draconian security legislation passed to segregate and intimidate. One of the most chilling laws passed during Vorster's leadership was the Terrorism Act of 1967 which allowed the police to detain indefinitely and in solitary confinement anyone suspected of "terrorism" - defined as anyone who might "endanger the maintenance of law and order" - or having information about terrorism. No court could intervene, and no one had access to the detainees. According to George Bizos, a celebrated human rights lawyer who represented many families of apartheid-era detainees, John Vorster's name became associated with detention without trial. "The name John Vorster inspired fears among detainees," said Bizos. One of the most common methods of torture used in John Vorster Square was "standing torture", during which detainees were prevented from sleeping or sitting down for many hours on end. At least 73 political activists are thought to have died in South African police detention between 1963 and 1990 - eight of them during or as a result of their detention at John Vorster Square. In spite of the work of the Truth and Reconciliation Commission (TRC) between 1996 and 1999, most of these cases remained shrouded in secrecy. That was until inquests into the deaths began to be reopened in 2017, in large part thanks to the tireless efforts of Imtiaz Cajee. "Imtiaz has been waging a long campaign for truth and justice," said Howard Varney, lawyer for the Timol family. The first inquest to be reopened was that of Ahmed Timol, the first activist who died at John Vorster Square. Ahmed Timol Born in 1941, Ahmed Timol, who was of Indian heritage
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13917, 43905, 582, 342, 253, 187, 15505, 273, 353, 7864, 44, 387, 670, 1458, 1229, 38040, 313, 338, 368, 403, 3345, 273, 3060, 13, 8028, 3066, 3829, 5267, 15, 999, 74, 15, 307, 11851, 70, 15, 13307, 27, 2511, 520, 16, 13441, 1244, 281, 3729, 187, 24573, 45999, 387, 34919, 14, 43943, 38040, 313 ]	they are moot, irrelevant, or without merit. To reflect the foregoing, Decision will be entered under Rule 155. Beta (20-28 Hz) and delta (0.3-3 Hz) EEGs oscillate reciprocally across NREM and REM sleep. Across-night oscillations of beta (20-28 Hz) and delta (0.3-3 Hz) electroencephalograms (EEGs) were examined with spectral analysis in 10 normal young adult subjects (Ss). In each S, power densities of beta were found to oscillate reciprocally with delta power density across both nonrapid eye movement (NREM) and rapid eye movement (REM) sleep. Linear correlation coefficients between log power density of delta vs. beta were significant (p less than 0.0001) for each S. An incidental observation was that beta power within REM was reliably lower in epochs with more eye movement activity. The reciprocal relationship between beta and delta holds implications for sleep physiology and supplements our earlier finding that sigma (12-15 Hz) oscillates reciprocally with delta within NREM sleep. These descriptions of the continuously varying EEG across sleep provide information not available when EEG measures are tabulated by discrete NREM periods and REM periods.As the legislation matures and more directives are formulated, more issues will undoubtedly come to light. To the credit of the office of the Information Regulator, there is a commitment to adopt privacy best practices from around the world. This should provide a solid basis from which to move forward with efforts to protect personal information in South Africa. The practical implications of PoPIA certainly needs considering. Our PoPIA Team has put together answers to a few of the questions being asked on PoPIA forums. How will POPIA protect my personal information collected by the security guards when visiting a complex/residential building? All responsible parties who collect PI for security reasons must ensure the prevention of loss, damage or unlawful processing of PI given for this purpose. In other words, if the PI you have given to gain access to a building is lost, processed unlawfully by another party or damaged in any way that would constitute a breach and as the data subject you would have recourse to the regulator. Does government get held to the same standard as private sector in the event of a breach? Yes, indeed. POPIA applies to all public institutions except for PI processed during a criminal investigation or investigation of any activities related to the financing of terrorism or money laundering. The exception also applies in cases considered sensitive for national security reasons as well as PI processed by the judiciary and the Cabinet. (See section 6 of POPIA) Would a General Practitioner (GP) need to disclose to all patients that they had a data breach, even if only one patient has been compromised? The GP would only have to disclose to the affected patients, unless the GP is ordered to publicise the breach by the information regulator. Who will be responsible if government departments share citizens’ personal information with companies e.g. sharing with SANRAL? I assume this question relates to SANRAL and e-tolling in South Africa. The lawfulness of e-tolling is being challenged by OUTA and is far more complex than the processing of PI. Exactly how sharing of PI across government agencies and different levels of government (i.e. municipal, provincial and national) will apply, I would suggest, will only be known once the Act is in force, regulation has been published and case law exists. The Act does specifically allow for the sharing of PI from private organisations with the South African Revenue Service. How are employees of companies affected by this law if they have access to client information on their mobile devices? Any personal information belonging to clients and stored on mobile devices must meet the security safeguards of prevention of loss, damage or unlawful processing. In practical terms, encryption of all mobile devices is the reasonable control to meet the minimum standards. How would an individual, like a family GP, be ‘punished’ for a data breach? Contravention of POPIA in South Africa will be a criminal offence. Any GP contravening the Act will face administrative penalties (fines) and/ or a prison sentence not exceeding 10 years. See chapter 11, sections 107 and 109 of POPIA. What are the POPIA directives for IT and processing environments? In terms of POPIA and the definition of processing, which includes the collection, storage, retrieval and dissemination of PI for lawful processing, any IT service provider would be deemed to be operators. The responsible party (that is, for example, GP practices) must ensure that all operators, including IT service providers, meet the minimum-security safeguards as contained in condition 7 of POPIA. Like this: Related Pétanque NXT We partner with companies who want to understand and integrate the new 4IR–driven possibilities to reduce cost, improve how they serve their customers and ensure their leadership position in the new business landscape.Utility Planet is the official blog for the column of the same name in The Spectrum Monitor. It replaces Utility World in the discontinued Monitoring Times magazine. Utilities are all VLF/LF/MF/HF (and sometimes low-band VHF) radio communications except broadcasting, CB, and non-emergency amateur. If you understood the last sentence, you know enough to read this blog. Friday, July 28, 2017 More broadcasters are making use of the 9400 kHz frequency from Space Line in Bulgaria. If you have ever considered producing your own radio program, either digital text or traditional voice, contact Space Line via spaceline.bg (I think Saturday 1630-1700 UTC is available!), or Radio Miami International via wrmi.net. (I do not work for or derive income from either transmission company.) This weekend, most of Shortwave Radiogram is in our usual MFSK32 mode, with five images. If reception is difficult, there is also one brief item from Radio Prague in Olivia 64-2000. Here is the lineup for Shortwave Radiogram, program 6, 29-30 July 2017, all in MFSK32 except where noted: The Mighty KBC transmits to Europe Saturdays at 1500-1600 UTC on 9400 kHz (via Bulgaria), with the minute of MFSK at about 1530 UTC (if you are outside of Europe, listen via websdr.ewi.utwente.nl:8901/ ).And to North America Sundays at 0000-0200 UTC (Saturday 8-10 pm EDT) on 9925 kHz, via Germany. The minute of MFSK is at about 0130 UTC. Reports to Eric: [email protected] . See also http://www.kbcradio.eu/ and https://www.facebook.com/TheMightyKbc/. Italian Broadcasting Corporation (IBC)For the complete IBC transmission schedule visithttp://ibcradio.webs.com/Five minutes of MFSK32 is at the end of the 30-minute English-language “Shortwave Panorama,” per the schedule below: WEDNESDAY18.55 UTC6070 KHZ TO EUROPE 19.55 UTC1584 KHZ TO EUROPE THURSDAY02.55 UTC1584 KHZ TO EUROPE FRIDAY01.25 UTC9955 KHZ TO CENTRAL/SOUTH AMERICA SATURDAY01.55 UTC 11580 KHZ TO NORTH AMERICA 20.25 UTC1584 KHZ TO SOUTH EUROPE SUNDAY00.55 UTC7730 KHZ TO NORTH AMERICA 10.55 UTC6070 KHZ TO EUROPE Thanks for your reports.I will begin sending replies and QSLs for SWRG program 4 this weekend.And I hope eventually to catch up! I was amazed how well the MFSK64 (240 wpm) performed last week, even under some marginal conditions. You can see videos of reception and decoding via this link: https://twitter.com/SWRadiogram/status/885863588677791746 . It would be tempting to use MFSK64 as our “default” mode, except that there would be enough instances of difficult reception that the number of errors would be unacceptable. Did anyone experience reception bad enough that only the MFSK16 provided a perfect decode? This weekend, let’s hope for bad reception – well, at least somewhere – because we will include some Olivia 64-2000 in show. This is a slow mode, only about 25 wpm. And it makes use of the entire 2000 Hz available to us, so you probably don’t want to use an extremely narrow filter. Also, for best results with Olivia 64-2000, turn the squelch (SQL at the bottom right of Fldigi) off. Here is the lineup for Shortwave Radiogram, program 4, 15-16 July 2017, all in MFSK32 except where noted: The Mighty KBC transmits to Europe Saturdays at 1500-1600 UTC on 9400 kHz (via Bulgaria), with the minute of MFSK at about 1530 UTC (if you are outside of Europe, listen via websdr.ewi.utwente.nl:8901/ ). And to North America Sundays at 0000-0200 UTC (
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This should be considered carefully when planning the contents and educational methods for the programs. There are approximately 30 intensive care units (ICUs) in Finland in which over 28,000 patients are cared for annually \[[@B1]\]. It is estimated that by the year 2030 the need for intensive and critical care will grow by 25%, for example, due to the fact that the Finnish population is getting older \[[@B2]\]. Multifactorial reasons increase the need of critical care beds in Finland and also in other countries in Europe. Intensive care unit nurses (ICU nurses) are the largest professional group working in the ICUs. Severely ill patients and families benefit from the attention of highly trained and skilled personnel \[[@B3], [@B4]\]. ICU nurses contribute to patient safety, such as improved patient outcomes, reduced morbidity and mortality, and decreased complications, errors, and overall costs \[[@B5]--[@B10]\]. Competent ICU nurses have a significant impact on ICU patient\'s physiological and psychological outcomes, for example, evidence based nursing interventions and ethical activity. Critical care nursing is an own nursing speciality \[[@B11]\] whereas technology is integrated with psychosocial challenges and ethical conflicts associated with critical illness \[[@B12]\]. Generally, critical care nursing education is a special postqualification education \[[@B13]\] and is described in the European Qualifications Framework for Lifelong Learning as level 6 (of eight) \[[@B14], [@B15]\]. Currently no postqualification education in intensive and critical care nursing leading to a degree exists in Finland. We know that there is a worldwide need for competent nurses \[[@B16]\]. In nursing practice, nurses get to demonstrate on a regular basis clinical competence as well as a sound theoretical knowledge base according to nationally recognized frameworks \[[@B4], [@B17], [@B18]\]. There is a need for valid specific instruments (e.g., for intensive and critical care nursing) for competence evaluation purposes. Competence evaluation can be performed in various ways, for example, using self-assessment, knowledge tests, peer evaluation (colleague), observation (mentor, supervisor), OSCE (objective structured clinical examination), or portfolios. The best way to perform competence evaluation is to combine different evaluation methods. Self-assessment is an essential ability that can be learned and developed during education and nursing career. Intensive and Critical Care Nursing Competence Scale research is scarce. Only three scales (Basic Knowledge Assessment Tool \[BKAT\], Intensive Care Hundred Item Test \[I-HIT\], and multilevelled critical care competency statements) of competence in intensive and critical care nursing are reported in nursing literature \[[@B19]\]. Of these scales, two are knowledge tests (BKAT + I-HIT) while the third one is based on nurses\' self-assessment; however, we are well aware that it has not been properly tested for reliability and validity and is still in its early phases. The need for a basic competence self-assessment scale in intensive and critical care nursing is therefore also evident, for example, for undergraduate education for beginning registered nurses practice standards. The systematic literature review conducted for this study in PubMed and search from critical care nursing organizations over the last ten years found 21 studies or documents of competence in intensive and critical care nursing (see the appendix). As a summary of the literature, competence concept is very multidimensional (e.g., focusing on clinical practice \[nursing process\], ethics, collaboration, leadership, education, and development work) and strongly related to, for example, age, work experience, and frequency of using specific competencies. Competence is studied worldwide (10 documents from Europe, 7 documents from Australia and New Zealand, and 4 documents from USA, Canada, and Brazil); thus, there is lacking systematic competence evaluation research. Evaluation is often performed by self-assessment \[[@B20]--[@B22]\] or knowledge test \[[@B23]\]. ICU nurses\' self-assessed competence was evaluated as ranging from moderate to excellent: from moderate to good (sample consisting of newly registered ICU nurses) \[[@B22]\], good (sample consisting of ICU nurses with varying work experience) \[[@B20]\], and from good to excellent (sample consisting of ICU nurses with varying work experience) \[[@B21]\]. European ICU nurses\' overall knowledge score was 66% of 100 points (min 22, max 91, and SD 12); the main factor that contributed to variance in scores is length of nurses\' intensive care experience. The knowledge category with the lowest score was respiration and ventilation \[[@B23]\]. The purpose of this empirical study was to describe and evaluate the self-assessed basic competence of intensive care unit nurses and related factors using a scale, Intensive and Critical Care Nursing Competence Scale version 1 (ICCN-CS-1) \[[@B11]\]. The related factors were divided into the following areas: (i) age and gender, (ii) education, (iii) work experience, (iv) information retrieval, (v) knowledge test, and (vi) others. The hypothesis was that the basic competence can be explained with these. This empirical study is part of a larger project where the scale was developed \[[@B19]\]. This study was conducted to facilitate establishment of the psychometric properties (reliability and construct validity) of the scale being used \[[@B24]\]. The project from which this study is a part aimed to define competence in intensive and critical care nursing (ICCN), to develop a basic self-assessment based measurement scale for competence evaluation in ICCN, and to describe graduating nursing students\' basic competence in ICCN by seeking reference basis from ICU nurses. ICU nurse is a registered nurse who practises in an ICU and whose nurse education is Bachelor of Health Care, specialist nurse, or nurse. In this ICU nurses basic competence study was used also the experience base of the ICU nurses in data analysis which were not analysed in graduating nursing students\' basic competence study. The students had no experience base enough in ICCN and therefore in data analysis only three bases of four were analysed knowledge, skill, and attitude and value bases. A novel issue in this study is that it highlights the multidimensionality of the concept of competence. Four bases of competence in intensive and critical care nursing were analysed in ICU nurses\' data: knowledge base, skill base, attitude and value base, and experience base \[[@B19]\]. ICCN-CS-1 measures basic competence and it refers to preliminary competence to practice in an ICU. It is comparable to step 1 competencies of the National Competency Framework for Adult Critical Care Nurses \[[@B25]\] and Critical Care Nurse Education Practice Standards \[[@B26]\]. ICCN-CS-1 is useful in planning supervision in preregistration nursing students\' clinical practice and during orientation programmes, for example, to identify learning gaps, define learning goals, and discuss competence in a comprehensive manner. The content of the scale is in line with postgraduate education standards and the competence standards of critical care nurses, also at specialist level. The scale measures the basic competence in intensive and critical care nursing and can be used as a starting point for the transition process from preregistration education to postgraduation education. The scale was developed for intensive and critical care education purposes, for example, for preregistration education and in orientation programmes. The results of this study can be useful in nursing education, especially in basic education and when planning continuous education. In clinical practice the results can also be helpful in professional performance appraisals in ICUs. 2. Materials and Methods {#sec2} ======================== 2.1. Aim {#sec2.1} -------- The aim of the study was to describe and evaluate the self-assessed basic competence of intensive care unit nurses and related factors. The results of this study will help educators, clinicians, and researchers to develop basic nursing education and orientation in the ICUs. 2.2. Research Questions {#sec2.2} ----------------------- The research questions for this study were as follows:What is the level of intensive care unit nurses\' self-assessed basic competence?What are factors related to the basic competence? 2.3. Design {#sec2.3} ----------- A cross-sectional survey design was employed using questionnaires among Finnish ICU nurses in university hospitals. 2.4. Sample/Participants {#sec2.4} ------------------------ Total sampling was used for ICU nurses in five Finnish university hospitals (n = 431 participants, response rate 54%). In one of the five university hospitals, a convenience sample of ICU nurses (n = 82 participants, response rate 37%) also completed a biological and physiological knowledge test. In 2008, a pilot study had been conducted in one university hospital; this organization was therefore not included in this data gathering in 2010. The final number of hospitals taking part in this study was thus four. 2.5. Data Collection {#sec2.5} -------------------- Data were collected using a questionnaire with the support of contact persons in the ICUs. The instruments used in this study were the Intensive and Critical Care Nursing Competence Scale (ICCN-CS-1) \[[@B24]\] and a knowledge test, the Basic Knowledge Assessment Tool version 7 (=BKAT-7) \[[@B27]\], which was used as the background factor in the convenience sample. Background factors (12) integral to the ICCN-CS-1 were asked and they formed the first page of the questionnaire. ICCN-CS-1 is a self-assessment tool consisting of 144 items (six sum variables). The scale measures basic competence in intensive and critical care nursing. Theoretically, basic competence is divided into clinical competence and professional competence. Clinical competence consists of three subdomains: principles of nursing care, clinical guidelines, and nursing interventions. Professional competence consists of four subdomains: ethical activity and familiarity with health care laws, decision-making, development work, and collaboration.
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368, 2509, 1476, 346, 3633, 896, 598, 1060, 1476, 346, 8262, 1476, 346, 43 ]	I'm sorry for pulling pranks." "It's 'cuz I liked you so much." "And I wanted to make sure you did, too." "I know you loved me." "I was always grateful." "I didn't say this before but" "I love you." "Se-jin," "I love you." "Stop!" "Stop!" " Sorry to keep you waiting." " It's okay, sir." "It's crazy around here today." "You probably already know why I asked you in here." "We're making some personnel changes." "You'll be sent to Line 3 as of tomorrow." "They're short of workers there." "Is there Seong-nae Station there?" "What?" "What about Han River on the way to Kang-byun Station?" "What are you talking about?" "I'm sorry, sir." "Resignation" "Why are you suddenly taking a year off?" "I'll probably look back on this and regret it." "But it hurts too much now" "I can't do anything." "Something came up." "I'm taking the year off." "Thank you for everything." "It's been months." "Don't you have anything to say?" "Wanna go for drinks?" "What?" "In this broad daylight?" "I don't get people who drink." "It's 'cuz they have weak will." " What's that on your shirt?" " Huh?" "I thought it was a dream." "I remember who was with me then." "What do you like?" "Out of the blue?" "Well, girls like shopping and clothes." "What about you?" "Sugar coated crullers." "And the zoo." "Try to learn to drink." "I like women who can drink well." "How much is enough?" "Maybe..." "a bottle of so-ju?" "A bottle of so-ju!" "A bottle of so-ju!" "What's that?" "Answer the phone, So-hyun!" "I found it!" "2494!" "This is where we first met." "Now, it's time to light up the Tree of Hope." "Ready?" " One!" " One!" " Two!" " Two!" " Three!" " Three!" " Is this Jin-man's phone?" " Ji-eun!" "Stupid, you didn't forget our promise?" "Ji-eun." "You look well." "Wait, Jin-man." "Please don't come to me." "I can't see you now." "I'm married." "I know." "I'm sorry," "I couldn't wait for you." "It's okay." "You kept your promise." "That's enough." "Are you happy?" "Yes." "Now I know why you wanted to meet on a total eclipse." "Why?" "'Cuz it's beautiful." "I'm just glad I can see it with you." "That'll do." "So-hyun!" "Don't go!" "There's something I have to tell you!" "I don't understand why you asked me to teach you how to drink." "Or why my shirt got stained by the iris." "And what it is you desperately want." "And why" "you have to just watch it from afar like a rainbow." "I don't understand." "So, I was thinking." "Will you teach me?" "Then I'll teach you what I didn't realize till now." "Why I've been so blind to someone so special." "I'll tell you everything." "Until you can drink a whole crate full of so-ju." "Se-jin, happy birthday!" "Happy birthday, Se-jin!" "I officially declare Se-jin Jang as Jon-won Lee's boyfriend." "Hi, Se-jin!" "It's me." "I want to start by apologizing." "All those pranks I pulled on you." "It's 'cuz you looked so cute when you panic." "I couldn't resist seeing it over and over." "I wanted to make many fun memories with you." "It feels like a dream when I'm with you." "I never want to wake up." "From my happy dream." "August 20th, 2003." "I saw him sleeping on the train again." "He seems nice." "Idiot!" "I kept staring but he just slept." "September 5th, 2003." "He glimpsed at me exactly 24 times today." "Was it the short skirt I was wearing?" "No." "He looked at my eyes." "Hello." " Hi." " Hi." "Joo-won," "Thank you for allowing me to dream." "Free hugs!" "Free hugs!" "That idea's worth a Nobel Peace Prize." "There's nothing warmer than a hug." "You're right." "Free hug." "Let's wait together." "Let's not get ahead of ourselves." "Or erase the past completely." "We'll just take it slow." "And wait together." "I'd like that." "No one can beat me at waiting." "Ji-woo?" "Can I ask you a favor?" "Sure, go ahead." "Can I touch your Adam's apple?" "So, this is how it feels." "There!" "GAM Woo-sung, CHOI Gang-hee UM Tae-woong" "JUNG Il-woo, LEE Yeon-hee RYU Seung-ryong, LIM Jung-eun" "Directed by LEE Han" "Presented by Big House I Vantage Holdings" "an Ozone Film production" "executive producers CHEONG Eui-seok, KIM Sun-yong, CHIN Hee-moon, JUNG Suk-young screenplay by SIHN Dong-ick" "producer KIM Sang-o" "My memories of her are sometimes so real the present seems more like a dream." "Memories." "They're like the wind." "You never know when or how it'll blow." "Sir?" "You haven't slept at all." "Anything I can help you with?" "Seoul..." "It must've changed a lot, right?" "How long have you been away?" "For 6 years." "I left the other half of my heart there." "And this one's pounding like a drum." "Hello?" "Son!" "It's dad." "Uh-huh." "Are you playing video games again?" "It's not just a game, dad." "I'm busy, gotta go." "That kid..." "A simple idea won't do." "We need a phenomenal event." "Like the World Cups, people going crazy." "Crazy, excited," "A total eclipse." "The moon's shadow covers the sun." "A total eclipse." "The sun and moon uniting as one." "Hey, mister!" "Wait!" "Love, First" "Good morning, sir." "Stop pacing, So-hyun!" "You're making me dizzy!" "Today's the last day for registering, right?" "You asked me that 3 times!" "Want me to say it again?" "Yes, today's the last day to register!" "That's strange." "Are you registering or not?" "Black bean noodles and dumplings!" " Over here, please." " Okay." " Good job everyone." " Bye." "Have a great day, ma'am." "Hey, So-hyun!" " Take out the dirty dishes." " Yes." "My only source of solace." "Excuse me." "Oh, hi!" "You came to register?" "Ah, yes." "But who..." " You're in Korean Lit, too?" " Yes!" "Sorry, I'm running late." "He doesn't remember me." "Oops, my bag." "Hey, wait!" "Yes?" "The sticker," "here." "Thank you." "Bye." "Seoul Metro" "The train is now departing." "Three years earlier Stop sulking, boy!" "I'm way older than you!" "If you don't like the way I talk, go find someone else." "Fine." "When we officially start dating," "I won't call you boy." "We've been seeing each other everyday for over a year." "You ignored me again!" "Man..." "How do we get home now?" "That was the last train." "We can't just take any train, when we have 'our train'." "There's no such thing as 'our train'." "Yes, there is!" "2494!" "That's our train!" "There's a tree scratched on the driver's compartment." "And it sounds louder than the others as it pulls in." "What's with that look?" "Honestly?" "You're bizarre." "Bizarre..." "Hey!" "I like that!" "It means I'm special and unique." "You don't love me, do you?" "No!" "That's not it!" "I do love you!" "Liar." "You don't believe anything I say." "How can I?" "You say you live in a dream world." "Let's try it again." "Close your eyes, slowly." "Then open the eyes of your heart." "Slowly." "Can you feel it getting brighter?" "Yeah." "Now, draw what's in your heart." "Joo-won, Hey!" "Let's go." "It's getting late!" "You still don't see what I see, do you!" "Hey!" "What are you doing!" "Get back up here!" "Hey!" "J
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310, 627, 247, 1039, 281, 755, 11274, 7822, 281, 513, 625, 281, 10013, 619, 4116, 32, 187, 29, 27074, 3348, 31, 9876, 13520, 1335, 897, 288, 69, 1148, 78, 32, 187, 29, 27074, 3348, 31, 496, 1227, 14069, 16, 13838, 1148, 78, 15, 8259, 627, 310, 12832, 642, 7533, 326, 403, 417, 440, 13982, 264, 187, 29, 72, 18, 9884, 2752, 3331, 31632, 690, 346, 360, 1945, 20181, 3, 3923, 285, 3663, 5230, 2289, 15, 43336, 16164, 281, 521, 1211, 2395, 15, 34882, 4438, 310, 671, 417, 4645, 327, 13520, 15, 6101, 3082, 281, 755, 896, 5230, 2289, 3066, 12141, 2395, 390, 1611, 13520, 32, 187, 29, 24330, 700, 31, 305, 18, 21712, 18981, 187, 29, 24330, 700, 31, 18793, 187, 29, 27895, 31, 308, 43, 14, 27, 891, 1694, 352, 15, 891, 574, 281, 513, 428, 80, 5192, 16242, 1450, 3614, 1450, 11667, 15, 681, 1450, 10754, 1419, 14, 45447, 568, 5672, 3, 428, 80, 5192, 16242, 1450 ]	so far. <TJ-> Bercik: more details please ... kernel version, what you've tried, etc. <Bercik> 3.13.0-19-generic, well.. I managed to mount bcache, make filesystem on it.. but when saving/reading from filesystem I don't see expected speeds. <TJ-> Bercik: Was this a fresh new install with new block devices, or conversion of existing file-system(s) <Bercik> It was a fresh install in VM, just to try out how bcache works. <Bercik> I added 2 disk after I finished installing OS. <TJ-> Bercik: If it's in a VM then performance would be dictated by the VM to some extent <interweb> hello <interweb> How do I can gpg a folder ? <oldchinaphone> ++ <Bercik> TJ-, sure, but I can cleary tell that it's not working properly. HDD gets 40MB/s SSD around 220MB/s <Bercik> even in benchmerks inside VM. <licnep> trying to install 14.04, I already freed some 170GB on my HD. What would the install side by side with windows button do? Should I just click that or partition manually? <kupo_> doesnt it ask you how much you want to use?like 8 gigs or whatever <licnep> forget it i think i'll do it manually just to be sure. What about just a single ext4 / partition and a swap partition? (how much swap do i need for hibernation if i have 4 gigs of ram? <licnep> kupo_: i already reduced the win partition by 170GB so all that space is empty and i will use it all for ubuntu <kupo_> swap.i think 500 Mb or 750 <kupo_> i did too much on mine on accident and did like 3 gigs. but oh well <licnep> if i recall correctly you needed swap to be at least as much as the ram for hibernation to work. But maybe that changed, i'm not sure <kupo_> 500 or under is enough easily <kupo_> you may be right <kupo_> which is why mine is 3.50 <kupo_> i have hibernation issues . and since i use SSD i just shutdown now <licnep> makes sense <licnep> yea i never managed to get hibernation to work on my old laptop <licnep> hopefully it will work on this one, but i know there are still a lot of problems about hibernation on linux <kupo_> yeah. it worked perfectly for me before. but since i reinstalled Os. i have to do it via terminal. then it works fine <TJ-> Bercik: Does "lsblk" show the bcache devices correctly configured? <Bercik> give me a moment plz. I clread configuration and starting over.. <levo> any idea about how to convert a text searchable pdf file to a pdf image file? (formulas in the former aren't readable in e-reader) <ningu> I'm getting some weird locale errors on a new server. I've installed language-pack-en-base, /etc/default/locale is set to en_US.UTF-8, and my env vars are set properly I believe. however I get errors like <ningu> perl: warning: Setting locale failed. <ningu> to make it stranger these errors occur for one user on the server but not another. <ningu> any idea what's going on or how to debug it? <drfoo_> greetings , doing a dist-upgrade ran into a snag <drfoo_> Processing triggers for man-db ... <Bercik> TJ-, sorry I just got a call and have to go. Are u available here most of the time? I'd like to continue with you if possible. <drfoo_> ...usr/lib/man-db/manconv -f UTF-8:ISO-8859-1 -t UTF-8//IGNORE -q: Segmentation fault (core dumped) <drfoo_> process is hung <drfoo_> whats the best way to get out of this? <drfoo_> kill process and reboot <Scotty__> Hello, Yesterday I updated my Compat drivers on kernel 3.8 After that My screen resolution is all messed up. Xrandr shows that the current resolution (incorrect one) is the only resolution this supports. I tried to add my normal resolution on xrandr but got nothing. I tried install fglrx drivers, but that didnt help either. Does anyone have any suggestions? <trism> ningu: try a: sudo locale-gen en_US.UTF-8; <Scotty__> It should be noted, that previous kernel versions without this driver and patch work fine. <ningu> trism: already did that :( <trism> ningu: what is the output you are getting from running: locale; <wieczorek1990> Handwritten music recognition survey. Still need some more replies. Please aid me: https://docs.google.com/forms/d/1wKc1yrfM4pwytpPDU91s5U14KxemtRUFtG7YOtgK7LQ/viewform <ningu> trism: it generates a bunch of locales including en_US.UTF-8 <ningu> trism: sorry, I ran locale-gen with no args <ningu> and the output was for that <blind> Is there a way to do an apt-get install and specify certificate and private key? I know I can put it in apt.conf.d/45rulesname but that's not working so i'd like to try it manually. <kane77> hi, what may be the reason that I cannot kill process? <TJ-> blind: See "man apt-get" and "--option" <kane77> I ran a game via Steam, but it was unresponsive so I used xkill to kill the window, but now I have a process that I'm not able to kill with kill -9 <ningu> trism: when I run "locale" I get: locale: Cannot set LC_CTYPE to default locale: No such file or directory <ningu> what is the default locale? <ningu> oh, wait. I think I see what's going on. <semak> Hello <Scotty__> It should be noted, that previous kernel versions without this driver and patch work fine. It should be noted that previous kernel verisons w/out the driver or patch work fine. Any suggestions? <blind> TJ-: have you done apt-get -o for ssl information before? maybe my syntax is wrong?: '' apt-get update -o "Acquire::https::example.com={Verify-Peer \"true\"; Verify-Host \"true\"; CaInfo \"/etc/apt/ssl/CA.crt\"; SslCert \"/etc/apt/ssl/user.crt\"; SslKey \"/etc/apt/ssl/user.key\";};" '' <TJ-> blind: ouch!!! <limac> hi I'm getting this error after installing bumblebee with nvidia-331 in ubuntu 13.10: ... the class has no package named 'primus-libs-ia32' ... <limac> anyone know what to do? <TJ-> blind: For that I'd use "--config-file" <blind> do you know, though, is that syntax correct? It's not working in a case where the conf file WAS working. <blind> hm using -c did work. so syntax must be incorrect.. <blind> everybody on google is only doing this for proxy info :\| <TJ-> blind: enable the Debug::* options <HelloWorld321> I like Empathy, but I don't notice it's notifications if I'm afk. I'm really only worried about my Momma, who's listed as my only "Favorite" contact. But its very normal for me to shut down my computer at the end of the day and see tray messages like "Are you there? Are you there?", and I'd like my Momma to think I'm not ignoring her. :( <HelloWorld321> So the question is: should I change IMs, or is there a way to get Empathy to do more to grab my attention? <cjae> Does ubuntu still use hdparm? <cjae> In /etc/hdparm.conf there is literally no settings that are not uncommented <g1_> My friend typed some "umask 000" command and lost root access. Cannot login to his own account. Recovery mode is also not showing on ubuntu. Any methods to get back root access via guest account or try ubuntu? <majorhat> g1_: hey <majorhat> Hey <blind> TJ-: i got it. i had to do -o Acquire::https::example.com::Verify-Peer="true" -o Acquire::
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44279, 273, 253, 5603, 13, 1677, 598, 281, 1110, 665, 1557, 281, 871, 352, 13, 22294, 441, 281, 352, 4414, 187 ]	soul of fatherly disbelief. _How could my seed contribute to such stupidity?_ Or maybe he would say: "Babes in the Wood?" knowing well that Jeremy knew nothing more. And so, guilty, irritated and with time on his hands, Jeremy stood in due course in the pizza-fragrant atrium of the library, shaking rain off his umbrella before going inside. "Back for that Babes in the Wood file," Jeremy said when he saw that Gil was manning the Social Sciences desk. Gil recognized Jeremy and offered something friendlier than a smirk, although not yet as unguarded as a smile. "You just can't get enough, can you?" the librarian said. "I have a problem." In the carrel he took a deep breath, eyes on the ceiling, before diving in. He read all the articles, top to bottom. When he finished each one he ticked it off on a separate list he had made and turned the sheets face down on the left side of the file folder. He drew a diagram on another piece of paper, a lopsided Stanley Park. He drew in the Reservoir Trail, where the bodies had been found. He marked the dates of death and discovery: 1947, 1953. He registered the fact that the bodies, thought to be a boy and girl for decades, surrendered the DNA of brothers when examined just a few years ago. He considered Miss Harker's story, plotting her course through the park as he imagined the day. He marked the spots where she had seen the woman with the children, entering the forest here, emerging near the bear cages over here, running through the rose gardens. He sketched the alternate routes she might have taken, looping into the forest and returning. He turned next to the handwritten notes. They were journal entries, a careful record, although the handwriting was exceedingly scattered. Letters slanted different directions within a single word, words themselves floating free of the lines or sinking into the line below. The pages looked old, although they were not dated with a year. Maybe the writer had been caught up in the precise limits of the moment being lived, and the future (in this case the future reader) had been an impossible abstraction. Jeremy took a breath, preparing himself, then read. _Some introductory words:_ [the text began] _It should be understood that my interest in this place is longstanding. I have expected for some time that I should return here once my study achieved a certain focus, and that this return might represent the culmination of all previous work_. Jeremy leaned back in his chair, rolled his head back and looked at the ceiling. "God," he said. How had he not seen it coming? These words were, to say the least, somewhat _Professorial_. Jeremy leaned forward again and considered the page more closely. The only thing wrong was the illegible handwriting, cursive but barely. Each letter, each stroke within each letter, was individual, separate from the word. As if the words might disassociate from one another any minute, the letters within each word disband and fly off the page. The Professor had only a few pretensions in the material realm, but penmanship and fine writing accoutrements were definitely two. Jeremy recalled him signing field trip approval slips with a LeGrand Montblanc Bordeaux, and for special occasions unsheathing a huge Pelikan fountain pen made of bottle-green glass with inlaid silver birds. His handwriting matched the equipment: elegant, aloof and singular. Broad, flat strokes (only a particular obscure nib would do) leaning distinctly left on the page, despite the Professor being right-handed. It was so dense and consistent from top to bottom that a complete page of his writing had a distinctive uniform brocade. And then there were the touches. The final _r_ in Papier, for example. It didn't finish in the little dimpled anthill you were taught in penmanship classes, but formed itself like the printed _r_ , a haughtier letter entirely: a short, sharp vertical stroke, with a flaring finish, tapering dramatically up and to the right. The same way, every time. Someone with bad handwriting and a similar interest? Was there anyone with a similar interest? A colleague? Jeremy read on. _What I couldn't have known is that Miss Harker would provide this focus. Witnesses, after all, are not my interest. The murder of the Babes in the Wood, as a murder in itself, was not really my concern. And yet I was interested in this girl, in how she had acted out her heartbreak at leaving Vancouver among these trees on the same day as the murder. And how by doing so she had unwittingly cemented herself into the story, into the landscape from which she had been uprooted, the same landscape of which these children had become a tragic part_. _I went and interviewed her earlier this year. We had tea, spoke at length. She told me the things I knew already: the woman, the two children. But she told me something else, far more interesting. She_ _told me of a premonition, a vision that unfolded under a cloud of fear. She thought she might have fainted; she found herself on her back, the forest rising above her. The air was suddenly dark and in the darkness the forest was filled with people, with sounds_. _When she came to, there had been a young man there. Skinny and ragged. He disappeared into the forest, but he had touched her forehead as she lay. She knew so, she said, from a smudge she found there later_. _Enter Caruzo. I have wondered about his role, and this visit (after many) I am determined to lay this matter finally to rest. I hope he will answer my questions. I hope also that I can last. This work presents a mental and physical test. Tonight, to begin, I will hike across the hillside a safe distance and set up my own camp_. _August 13_ _Drizzling at seven-thirty in the evening_... There followed a week of weather reports, while the author waited for Caruzo to reappear. Then, a little further down: _August 21_ _We aren't talking about much yet, but he has consented to show me around. Caruzo, for the record: tall and heavy, 230 pounds. Age difficult to guess: fifty, sixty even. Large nose. Black and grey, distant eyes; he is caked in evidence of his surroundings. Dirt lines his face and neck and lives under his nails_. _What I know about his past is limited. He speaks of voices. He was institutionalized at one point. Received electroshock. Schizophrenia, I believe_. _He carries nothing, has no evident totem. No toby. Talks in riddles, repeating words like incantations. His are mad, angelic ramblings_. The weather reports and geographic detail resumed as Caruzo slipped out of reach into the forest. Jeremy skimmed down two weeks to find where the story resumed. _September 9_ _Caruzo has returned. Two excellent days of work. He talks lately of our estrangement: from the earth, from "the garden." He said something very odd: "The two are meant to be together. Just as the two were drawn from the same soil, so too must the same soil hold them, and through it must they be reconciled."_ _He speaks of the children, I'm sure. As if the wrong might be righted by his long presence here. And I sense it is a long time. When asked, he did not appear to know that it is 1987_. _Will the '90s bring better things for him? I don't think anyone in the city yet understands what he might be saying, what he might represent: the first of a latter-day generation that will live as he does_. _An aside: Dr. Tully hung up on me this morning. He rejects this data gathering technique. "We do not believe that anecdote is evidence," he said_. _On other fronts, Hélène grieves. I have broken with my normal practice and begun to call. Each time there are many, many tears_. Jeremy pulled his head out of the carrel sharply. When it came, he thought, understanding came suddenly. _1987. Hélène_. Jeremy hunched back over the yellow pages, reading and rereading the sentences with a new hunger. _Mid-September_ _I have been granted sick leave_. _September 24_ _I have begun to feel less like a visitor and more like a resident, an altogether unexpected pleasure. Caruzo has shown me much. He has covered my tent with maple leaves that overlap downwards and spread onto the ground. In the wet they facilitate run-off and minimize flooding_. _I have lately begun to realize how permanent this arrangement could be. Caruzo has shown me a simple snare for squirrels, a lasso of_ _copper electrical wire. He has shown me how to catch starlings on a stick with peanut butter and glue. Ducks may be netted, although the technique is fiendishly difficult. I am changed by this selective and respectful harvest. The bounty of the park, given up to those who care to know it, binds us to it_.
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1895, 13, 533, 352, 3133, 281, 789, 15, 5838, 326, 275, 619, 1083, 13, 309, 878, 253, 35985, 43124, 281, 320, 908, 751, 23762, 891, 15, 70, 15, 281, 1379, 2169, 49280, 685, 667, 273, 253 ]	various public figures they meet. I honestly believe you can learn quite a lot about a person by watching the way he or she interacts with a person with a disability. In that sense I have found that the conversations which take place before our cameras are often more revealing than the supposedly hard hitting interviews we see on major networks. What I particularly like about this latest film is the chance to watch the way political figures, and the many handlers surrounding them, work so hard to manipulate the way they are portrayed in the media. Often the most interesting part of the interview for us is not the actual interview at all. It's the slightly uncomfortable negotiation which takes place beforehand as we ask them if they will speak with us. I liked being able to include those discussions in this new film. In the past we didn't have the freedom, or good sense, to do that. Arthur Bradford: Over the years we have endeavored to produce How's Your News in many different ways, as a film festival entry, a DVD, an HBO documentary, and even an MTV series. This latest version, a completely independent, pay-per-view online stream/download, is truly the best form of distribution yet. For those of you who feel frustrated by commercial news media, I really urge you to support this kind of thing. Not to get on a high horse, but hey, this is It's the future of independent media. It's a very good thing. Boing Boing/XJ: What's it like working with the correspondents? Arthur Bradford: I've known all of them for so long now, they are some of my oldest friendships. And I do mean friendships. I first met Jeremy when he was just a kid, seven or eight years old. He was a crazy little ball of energy and we all wondered what he was going to be like when he grew up. Would people still think he was cute and charming? He's grown up now and, well, you can decide. Sue calls me up at least once a week, usually more. She is relentless when she's got something on her mind. This latest "How's Your News?" project came about in part because of her prodding. She was leaving messages on my phone saying, "Is this How's Your News horse dead or what? Come on!" Bobby is like an uncle to me. He was an usher at my wedding and plays with my children. I honestly don't know of anyone who can so easily mix and mingle with such a wide array of people. You could take him to a Hell's Angles rally in the morning and he'd have everyone hugging him and then attend a formal White House luncheon an hour later and he'd be cozying up the the Secretary of State. He'd know just how to behave immediately. It's a skill few of us have. I hold our reporters to a high standard. I often feel like I'm the coach and they are my team. I have to assess who is feeling good and who will interact in the most interesting way with a given interviewee. I sometimes get frustrated with the reporters if they ask banal questions or act shy. I let them know it when I think they can do better. But I never feed them questions. That doesn't come off well. The questions need to come from them. If they are not having a good time and showing genuine curiosity then it's not enjoyable to watch. I find directing How's Your News to be exhausting and draining and usually after each one is done I swear I'll never do it again. But then Sue and Jeremy starting calling me up and we end up hitting the road. And in the end I'm glad we do it. Download the documentary. (All images courtesy Arthur Bradford)Sidraž Sidraž () is a settlement in the Municipality of Cerklje na Gorenjskem in the Upper Carniola region of Slovenia. Geography Sidraž is a hill settlement in a shady location east of Šenturška Gora on a saddle between Doblič and Tunjščica creeks. The soil is loamy and there is a spring near the village. Name Sidraž was mentioned in historical sources in 1421 as Schydrachs (and as Sidras in 1449, Sydrasch in 1458, and Schidrass in 1475). The name is of unclear origin. A proposed derivation from *suhi draž is very unlikely for phonological reasons, and the village name is more likely based on a truncated personal name. References External links Sidraž at Geopedia Category:Populated places in the Municipality of Cerklje na GorenjskemThis application is related to co-pending U.S. application Ser. No. 09/429,519 for A METHOD AND APPARATUS FOR COMMUNICATION USING PULSE DECODING, filed Oct. 28, 1999 and to co-pending and co-owned U.S. application Ser. No. 09/805,854 for METHOD AND APPARATUS TO RECOVER DATA FROM PULSES, filed Mar. 13, 2001, both of which are owned by the Assignee of the present invention and are herein incorporated by reference for all purposes. This invention relates generally to a communication technique and more specifically to techniques for communication by converting arbitrary analog waveforms to sequences of pulses. In co-pending, commonly owned U.S. application Ser. No. 09/429,519, the communication system illustrated in FIG. 1 shows that groups of pulses are supplied to a decoding (decision) device 14. The decoder disclosed therein recovers data from the pulses; for example, by counting pulses. Additional recovery techniques are disclosed in co-pending, commonly owned U.S. application Ser. No. 09/805,854. It is desirable to increase the robustness of systems which employ the techniques disclosed in the foregoing identified applications. The utility of such systems can be further increased by increasing their information carrying capacity. According to the invention, a method and apparatus for a communication circuit is provided to recover information in a received signal. The communication circuit comprises at least two receiver circuits. The received signal is fed to each receiver circuit. Each receiver circuit is configured in accordance with the invention to produce output comprising a group of one or more pulses in response to detecting some portion of the received signal. The output of each receiver is fed to a decision device, which produces one or more symbols. In one embodiment of the invention, the groups of pulses from each receiver are processed by the decision device to produce a single symbol. In this embodiment of the invention, information transmission is more robust due to the redundancy of the information. In another embodiment of the invention, the groups of pulses from each receiver are processed to produce a symbol from each such group, thereby enhancing information carrying capacity.Sn Ag Solder You May Also Like: Sn-Ag lead free solder is developed as an alternative of lead solders. Generally, commercial tin/silver alloy contains 3% to 5% silver. The Sn/Ag series solders are widely used in soldering electronic assemblies; besides, it is applicable for soldering of jewelry due to its solder point is of high brightness. Unlike the conventional lead solders, they can be utilized in pipe joints which have contact with water and foodstuffs. Sn-Ag lead free solder is featured with high melting point and strong thermal strength. As professional tin silver alloy solder maker, we provide various Sn-Ag solders. The typical product is Sn95Ag5 tin silver solder wires and bars.Q: Content Search and Azure how to move items to the bottom of search results with boosting Similar to my earlier question, I need a way to move certain items to the end of my search results, without using ordering. I have a checkbox field (currently indexed as a string, containing "1" or "0"). I need the checked items ("1") to be at the bottom of the results. Normally, it would be possible to do this with ordering, but since I am boosting certain fields, applying ordering operations screws up the result relevancy. I have a method which adds predicates to my IQueryable object containing: queryable.Where(item => item["discontinued"].Equals("1").Boost(1.0f) \|\| item["discontinued"].Equals("0").Boost(4.0f)); I found from my earlier question that you cannot use negative boost values with Azure search, so I instead tried to give a higher boost for the unchecked items than the checked ones. Is this even possible?: to use two different boost values against the same field depending on the value?. My current testing seems to show that this does not work. A: I found this article which shows a similar approach to boosting (see the end of last code sample, toward the bottom) which confirms that my logic was correct. The error was my choice of boost values. I am boosting around 15 other fields with values in the range of 24 to 50. I guess that in order for this boost rule to have greater influence than the other ones it needs to be orders of magnitude greater (probably) than the other boost values (this must depend on the number of boosted fields and the frequency of occurrences of search terms). What I found was that upping the boost for non-discontinued items to 1000 fixed the problem. Not a very scientific way to fix the problem, but it seems to work. Note that in my case, I need the discontinued boosting to be used like sorting i.e. to take higher precedence than any of the
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1818, 281, 253, 12207, 3739, 14, 71, 3178, 474 ]	. The heavy warm gear is turning in my stomach. My hand is the hand of a stranger. Music is still playing. I must have swayed to the music because Winnie Gunn has seized my forearm with both hands. "Are you all right, Doctor?" she whispers. "Fine." "We are still waiting for your diagnosis, Dr. More," says Buddy with the gentleness of victory. "I found no significant pathology." "Louder!" from the back benches. The Director cups his ear. "I said I found no significant pathology." "No significant pathology," says Buddy as gently as Perry Mason beating Hamilton Burger for the thousandth time. "And what is your recommendation, Doctor?" "Discharge him." "Discharge him," repeats Buddy. "He can't walk or talk, and if he could, he would presumably return to his former atrocious behavior. And yet you want to discharge him. As cured, Doctor?" "If indeed there was nothing wrong with him." "You think there was nothing wrong with him?" "No. That is, yes." "Then what's he doing here in a wheelchair?" Titters. I shrug. "Dr. More, what do you think his chances are of recovering from his stroke?" "You mean, assuming he's had one." "Very well. Assuming he's had one." "Very small." "And if he did recover, what are the chances he'd return to his former mode of behavior?" "Very large." "Do you recall his former behavior?" I am silent. "Allow me to refresh your memory, Doctor." Again Buddy flips through the chart. "These," he explains to the amphitheater, "are progress reports during the last year of the patient's residence at the Golden Years Senior Citizen Settlement in Tampa. I quote: "'The subject has not only refused to participate in the various recreational, educational, creative, and group activities but has on occasion engaged in antisocial and disruptive behavior. He refused shuffleboard tournament, senior softball, Golden Years gymkhana, papa putt-putt, donkey baseball, Guys and Gals à go-go, the redfish rodeo, and granddaddy golf. He refused: free trip to Los Angeles to participate in Art Linkletter III's "the young olds," even though chosen for this trip by his own community. "'Did on two occasions defecate on Flirtation Walk during the Merry Widow's promenade. "'Did on the occasion of the Ohio Day breakfast during the period of well-wishing and when the microphone was passed to him utter gross insults and obscenities to Ohioans, among the mildest of which was the expression, repeated many times: piss on all Ohioans! "'Did in fact urinate on Ohio in the Garden of the Fifty States. "'Was observed by his neighbors on Bide-a-wee Bayou to be digging furiously with a spade on the patio putt-putt, defacing same. When asked what he was digging for, he replied: the fountain of youth.'" More titters from the student roosts. Buddy goes on: "'Despite extensive reconditioning in the Skinner box, the patient continued to exhibit antisocial behavior. This behavior,'" Buddy hastens to add, "'Occurred before his stroke last month.'" "If he had a stroke," I say. "If he had a stroke," Buddy allows gravely. "Well, Doctor?" "Well what?" "What would you do with him?" "Discharge _him_." "To suffer another thirty years?" asks Buddy, smiling. "To cause other people suffering?" "At least he'd have a sporting chance." "A sporting chance to do what?" "To avoid your packing him off to Georgia, where they'd sink electrodes in his head, plant him like a carrot in that hothouse which is nothing more than an anteroom to the funeral parlor. Then throw the Euphoric Switch—" "Doctor!" interrupts the Director sternly. "Aaah!" The students blush at the word _funeral_. Girls try to pull their dresses down over their knees. Buddy flushes angrily. The Director is angrier still. "Doctor!" He levels a quivering finger at me, then crooks it, summoning me. Craning down, he croaks into my ear. "You know very well that the patient is present and that there is no guarantee that he cannot understand you." "Excuse me, sir, but I hope—indeed I have reason to believe—that he does understand me." The Director goes off into a fit of coughing. His eyes bulge glassily. Handkerchiefs fly in and out of plackets in his coat. The students are in an uproar. Cheers from the Knotheads, boos from the Lefts. "This is too much!" The Director throws up both hands. Now he's grabbed me, hooked me with his claws like the ancient mariner. "It's my mistake, Doctor," he croaks. "My putting you on patient-staff status. I beg your pardon. It is only too clear that your illness does not yet permit you to function." "I can function, sir," I tell him, speaking into his great hairy convoluted ear. "You'll see." "Be careful, Doctor!" The powerful old hands squeeze my arm by way of warning. "Proceed!" Mr. Ives's bright monkey eyes have begun to snap again. "I repeat," I say to the back rows. "If Mr. Ives is going to be referred to Happy Isles of Georgia, which is nothing but a euthanasia facility, he has the right to know it and to prepare himself accordingly. And he has the right to know who his executioner is." "I warned you, Doctor!" The Director is on his feet and shouting. "Perhaps you'd better go back to the ward, to A-4." "Yes sir," I say. Perhaps he is right. The students, struck dumb, gaze at me, gaze at each other. "Sir!" It is Buddy, advancing toward me, hands clasped behind his back. He holds one hand up to quiet the uproar. The other hand is still behind him. "Sir!"—to the Director, in a loud voice. "I submit to you, sir, that you are mistaken!" "Eh?" The Director cups his ear. "Sir, you do an injustice both to Dr. More as well as to your own clinical judgment!" "Eh? How's that?" "Your first decision about Dr. More was quite correct. Your confidence in him is not misplaced. His illness does not in the least interfere with his functioning. In short, sir, I submit to you that his odd behavior today cannot be laid to his illness at all. The truth is—" Buddy, quick as a cat, steps behind me, embraces me with one arm, with the other hidden hand claps a mask over my face. His grip is like iron. There is nothing to do but squirm and, at length, gasp for breath. Three, four, five seconds and Buddy flings one arm up like a cowboy bulldogging a steer. He holds the dial aloft for all to see, presents it to the Director like the bull's ears. "Point three percent ethyl alcohol. The truth is Dr. More is drunk as a lord!" Relieved laughter from the students—along with the gasps. At least they recognize a familiar note of buffoonery. Even the Director looks relieved despite himself. "Fun is fun," he announces to no one in particular. "But The Pit may be getting out of hand." Moira has shrunk even farther into the tunnel. Unbuckling my physician's bag, I take out my modified lapsometer. Buddy makes way for me, giving my arm a friendly squeeze, handing me on to the patient with a reassuring smile. _You see,_ his smile tells the students, _it's all in the spirit of The Pit. More and I are not mad at each other._ "Your patient, Doctor." Your witness, Mr. Burger. Twenty years and Ham Burger never won a case. "Thank you, Doctor, but I don't want the patient. I want you." A beehive murmur. Buddy holds up both hands. "It's all right!" he cries, smiling. "Turnabout is fair play. Dr. More is going to diagnose me. Why not? He is going to measure, not my blood alcohol, but my metaphysical status. The device he holds there—correct me if I'm wrong, Doctor—is the More Quantitative-Qualitative Ontological Lapsometer." Laughter from the left. "Qualitative-Quantitative," I correct him. More laughter from the left. Consternation from the right benches. Stony stares from my colleagues. But the Director's glossy eyes bulge amiably—at least he is relieved to see the tone change to the acceptable medical-farcical
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= 0; i < elements.length; i++) { if (elements[i].value != volume) elements[i].value = volume; } Lunettes.didChange(this, "volume"); }, /** * @param {Event} event / timelineValueChanged: function(event) { var target = event.currentTarget; if (window.PlatformView.isSeekable()) window.PlatformView.setPosition_(target.value / target.getAttribute('max')); }, _position: 0, get position() { return this._position; }, set position(newPosition) { if (!newPosition) newPosition = 0; if (this._position == newPosition) return; this._position = newPosition; var elements = document.getElementsByClassName(this.Exported.ClassNames.timeline); for (var i = 0; i < elements.length; i++) elements[i].value = newPosition elements[i].getAttribute('max'); }, PlatformWindowController: function() { return window.PlatformWindowController; }, PlatformWindow: function() { return window.PlatformWindow; }, /** * @param {string} className / contentHasClassName: function(className) { var content = document.getElementById(this.Exported.Ids.content); return content.hasClassName(className) != -1; }, /* * @param {string} className / removeClassNameFromContent: function(className) { var content = document.getElementById(this.Exported.Ids.content); content.removeClassName(className); }, /* * @param {string} className / addClassNameToContent: function(className) { var content = document.getElementById(this.Exported.Ids.content); content.addClassName(className); }, // JS -> Core close: function() { this.PlatformWindow().performClose(); }, miniaturize: function() { this.PlatformWindow().miniaturize(); }, zoom: function() { this.PlatformWindow().zoom(); }, /* * @param {Event} event / togglePlaying: function(event) { if(this.contentHasClassName(this.Imported.ClassNames.playing)) window.PlatformView.pause(); else window.PlatformView.play(); event.preventDefault(); }, /* * @param {Event} event / enterFullscreen: function(event) { this.PlatformWindowController().enterFullscreen(); event.preventDefault(); }, /* * @param {Event} event / leaveFullscreen: function(event) { this.PlatformWindowController().leaveFullscreen(); event.preventDefault(); }, videoResized: function() { if (window.PlatformView.videoDidResize) window.PlatformView.videoDidResize(); }, windowResized: function() { this.videoResized(); }, windowFrame: function() { var platformWindow = this.PlatformWindow(); var origin = { x: platformWindow.frameOriginX(), y: platformWindow.frameOriginY() }; var size = { height: platformWindow.frameSizeHeight(), width: platformWindow.frameSizeWidth() }; return { origin: origin, size: size }; }, /************************************************ * Event handlers / /* * Key events * @param {Event} event / keyDown: function(event) { var key = event.keyCode; // Space" key if (key == 0x20) this.togglePlaying(); }, // Common mouseDownPoint: null, windowFrameAtMouseDown: null, /* * @param {Event} event / saveMouseDownInfo: function(event) { this.mouseDownPoint = { x: event.screenX, y: event.screenY }; this.windowFrameAtMouseDown = this.windowFrame(); }, /************************************************ * Window Drag / /* * @param {Event} event / mouseDownForWindowDrag: function(event) { // It is reasonnable to only allow click in div, to mouve the window // This could probaby be refined if (event.srcElement.nodeName != "DIV" \|\| event.srcElement.hasClassName(this.Exported.ClassNames.resizePlatformWindow) \|\| event.srcElement.hasClassNameInAncestors(this.Exported.ClassNames.dontDragPlatformWindow)) { return; } this.saveMouseDownInfo(event); // Sometimes we may get multiple mouseDown but no mouseUp // make sure we don't register the listener twice. if (this._mouseUpListener) return; this._mouseUpListener = this.mouseUpForWindowDrag.bind(this); this._mouseDragListener = this.mouseDraggedForWindowDrag.bind(this); document.addEventListener('mouseup', this._mouseUpListener, false); document.addEventListener('mousemove', this._mouseDragListener, false); }, /* * @param {Event} event / mouseUpForWindowDrag: function(event) { document.removeEventListener('mouseup', this._mouseUpListener, false); document.removeEventListener('mousemove', this._mouseDragListener, false); this._mouseUpListener = null; this._mouseDragListener = null; }, /* * @param {Event} event / mouseDraggedForWindowDrag: function(event) { var dx = this.mouseDownPoint.x - event.screenX; var dy = this.mouseDownPoint.y - event.screenY; var mouseDownOrigin = this.windowFrameAtMouseDown.origin; this.PlatformWindow().setFrameOrigin__(mouseDownOrigin.x - dx, mouseDownOrigin.y + dy); }, /************************************************ * Window Resize / /* * @param {Event} event / mouseDownForWindowResize: function(event) { // It is reasonnable to only allow click in element that have a resize class if (!event.srcElement.hasClassName(this.Exported.ClassNames.resizePlatformWindow)) return; this.saveMouseDownInfo(event); this.PlatformWindow().willStartLiveResize(); this._mouseUpForWindowResizeListener = this.mouseUpForWindowResize.bind(this); this._mouseDragForWindowResizeListener = this.mouseDraggedForWindowResize.bind(this); document.addEventListener('mouseup', this._mouseUpForWindowResizeListener, false); document.addEventListener('mousemove', this._mouseDragForWindowResizeListener, false); }, /* * @param {Event} event / mouseUpForWindowResize: function(event) { document.removeEventListener('mouseup', this._mouseUpForWindowResizeListener, false); document.removeEventListener('mousemove', this._mouseDragForWindowResizeListener, false); this.PlatformWindow().didEndLiveResize(); }, /* * @param {Event} event */ mouseDraggedForWindowResize: function(event) { var dx = event.screenX - this.mouseDownPoint.x; var dy = event.screenY
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716, 391, 8864, 268, 28669, 247, 294, 256, 246, 891, 298, 298, 277, 891, 256, 247, 270, 298, 299, 277, 964, 3166, 295, 299, 260, 299, 23524, 552, 1178, 8777, 13, 7461, 11, 14760, 783, 278, 8480, 43096, 9, 13217, 64, 67, 9582, 558, 23320, 64, 1116, 6395, 12467, 64, 1282, 39108, 20704, 64, 5478, 39108, 20704, 64, 423, 558, 3541, 64, 5478, 30, 81, 2977, 64, 4478, 9, 20704, 64, 5478, 13, 20704, 64, 423, 558, 85, 1761, 64, 4478, 1874, 4478, 64, 27209, 1874, 31062, 64, 4478, 1874, 673, 64, 891, 295, 891, 246, 313, 2387, 3706, 268, 549, 256, 299, 795, 258, 268, 246, 891, 258, 295, 256, 9, 260, 258, 278, 278, 271, 277, 64, 298, 275, 299, 10, 3706, 6401, 41, 329, 17939, 34, 418, 444, 416, 308, 2195, 308, 288, 891, 256, 891, 256 ]	=ints[1]&1;}staticvoid__initramdisk_size(charstr,intints){if(ints[0]>0 &&ints[1]>=0)rd_size=ints[1];}#endifstaticint__initchecksetup(charline){inti,ints[11] ;#ifdefCON FIG _ B L K _ D E V _ I D E/ i d e d r i v e r n e e ds t he b a s i cs tri n g , r ath e rtha npre-processedvalues/if(!s trncmp(line,"ide",3)\|\|(!strncmp(line,"hd",2)&&line[2]!='=')){ide_setup(line);re turn1;}#endiffor(i=0;raw_params[i].str;i++){intn=strlen(raw_params[i].str);if(!strncmp (line,raw_ p a r a m s [ i ] . s t r , n ) ){ ra w _ p a ra m s [ i ].setup_ fu nc(li n e + n, N U L L ) ; return1;}}for(i=0;cooked_p arams[i].str;i++){intn=strlen(cooked_params[i].str);if(!strncmp(line,cooked_par ams[i].str,n)){cooked_params[i].setup_func(get_options(line+n,ints),ints);return1;}}re turn0;}/t h i s s h o u l d b e a p p r o x 2 B o * o M i p st o st a r t ( not e i ni t i a lsh i f t ) , a n d w i llstillworkevenifinitiall ytoolarge,itwilljusttakeslightlylonger/unsignedlongloops_per_sec=(1<<12);/Thi sisthenumberofbitsofprecisionfortheloops_per_second.Eachbittakesonaverage1.5/HZseconds .This(lik e t h e o r i g i n a l ) i s a l i tt l e b e t t er tha n 1%* / #d ef ineLPS_PREC 8 v o i d _ _ i nitcalibrate_delay(void ) { unsignedlongticks,loopbit;intlps_precision=LPS_PREC;loops_per_sec=(1<<12);prin tk("Calibratingdelayloop...");while(loops_per_sec<<=1){/waitfor"startof"clocktick/ti cks=jiff i e s ; w h i l e (t i c k s= = j if f i e s) / not h ing /;/ G o . . /t i c k s = ji f f i e s ; _ _ delay(loops_per_sec);tic ks=jiffies-ticks;if(ticks)break;}/Doabinaryapproximationtogetloops_per_second settoequaloneclock(uptolps_precisionbits)/loops_per_sec>>=1;loopbit=loops_per_sec;whi le(lps_ p r e c i s i o n -- && ( l o o p b i t> > = 1 ) ) { loo p s _ p er_ s e c\| =loo p bit;ti c k s=j i f f i es;while(ticks==jiffies) ;ticks=jiffies;__delay(loops_per_sec);if(jiffies!=ticks)/longerthan1tick/loo ps_per_sec&=~loopbit;}/finally,adjustloopspersecondintermsofsecondsinsteadofclocks/l oops_p e r _s e c * = H Z ; / * R o u n d t h e va l u e a n d pr int i t/ p r in tk ( "%lu. % 02 l uB o goM I P S \ n",(loops_per_sec+2500) /500000,((loops_per_sec+2500)/5000)%100);}/Thisisasimplekernelcommandlinepar singfunction:itparsesthecommandline,andfillsinthearguments/environmenttoinitasapprop riate. A n y c m d - l i n e o p t i on i s t a k e n t o b eane n v ironm ent v a ri a bleifitco n t a i n s t h echaracter'='.*Thisro u tinealsochecksforoptionsmeantforthekernel.Theseoptionsarenotgiventoinit-theya reforinternalkerneluseonly./staticvoid__initparse_options(charline){charnext;intarg s,env s ; if ( ! l i n e ) r et u r n; a r g s = 0 ; e n vs= 1;/ * TER Mi ssetto'l i n u x'by d e f a u l t * / n ext=line;while((line=ne xt)!=NULL){if((next=strchr(line,''))!=NULL)next++=0;/checkforkerneloptionsf irst../if(!strcmp(line,"ro")){root_mountflags\|=MS_RDONLY;continue;}if(!strcmp(line,"r w")){ r o o t _ mo u n t f l a g s & = ~ M S _ R D O N L Y ; co nt i n u e ; } if(!s t rc m p(line , "d e b u g ") ) { console_loglevel=10;cont inue;}if(!strncmp(line,"init=",5)){line+=5;execute_command=line;/IncaseLILOis goingtobootuswithdefaultcommandline,itprepends"auto"beforethewholecmdlinewhichmakest heshe l l t h i n k i t s h o u l d e x ecut e a s c ri ptw it h suc hn am e .S o weigno r e a l l a r g u m e n t s entered_before_init=... [MJ]/args=0;continue;}if(checksetup(line))continue;/Thencheckifit'sanenviro nmentvariableoranoption./if(strchr(line,'=')){if(envs>=MAX_INIT_ENVS)break;envp_init [++en v s ] = l i ne ; } e lse { i f ( a r g s > = M A X _ I NI T _A R G S)brea k ;arg v _ i ni t [ + + a r g s ] = l i ne;}}argv_init[args+1]=N ULL;envp_init[envs+1]=NULL;}externvoidsetup_arch(char,unsignedlong,unsigned long);#ifndef__SMP__/Uniprocessoridlethread/intcpu_idle(voidunused){for(;;)idle() ;}#de f i n e s m p _ i n it ( ) d o{ } whi l e ( 0 ) #el s e / M ul t i p r oces s or i dle t h r ead i s i n a r ch/.../externintcpu_idle (voidunused);/Calledbybootprocessortoactivatetherest./staticvoid__initsmp_ init(void){/Getotherprocessorsintotheirbootupholdingpatterns./smp_boot_cpus();smp_th reads _ r e a d y = 1 ; s m p _ c o m m e n c e ( ) ; } # e ndifex te rnvoidin i ti a liz e _ s ec o n d a r y ( v o id);/Activatethefirstpro cessor./asmlinkagevoid__initstart_kernel(void){charcommand_line;#ifdef__SM P__staticintboot_cpu=1;/"current"hasbeensetup,weneedtoloaditnow/if(!boot_cpu)initial ize_s e co n d a r y ( ) ; bo ot _ c p u =0 ; # e n d if/ * In te r ru p ts a re s t i l l d i s a b l e d . Do n e c e ssarysetups,thenenablethe m/printk(linux_banner);setup_arch(&command_line,&memory_start,&memory_end); memory_start=paging_init(memory_start,memory_end);trap_init();init_IRQ();sched_init(); time_ i n i t ( ) ; p ar s e _ o p t i o n s( c o m m an d_ l in e) ; /**H A CKA L E R T ! T h i s i s
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1691, 1110, 2127, 715, 327, 49, 766, 15, 187, 1394, 476, 923, 625, 2508, 275, 436, 3048, 27, 43901, 27230, 34356, 187, 19576, 436, 1501, 588, 4217, 323, 3780, 16382, 1072, 1895, 342, 479, 15, 535, 50, 27, 187, 187, 6723, 253, 2264, 3221, 37865, 285, 3221, 2297, 3993, 273 ]	<provider selected="true" editor-type-id="text-editor"> <state relative-caret-position="153"> <caret line="9" column="5" selection-start-line="9" selection-start-column="5" selection-end-line="9" selection-end-column="5" /> </state> </provider> </entry> </component> </project>Article content continued The company may need to set aside funds for a US$16.7 million note maturing in November, apart from as much as US$110 million maturing next April, according Raymond James analyst Andrew Bradford, although lenders are expected to provide debt relief. “Lenders would be far better off to amend covenants and work with operators through the downturn if for no other reason than equipment liquidated through a receiver could effectively go ‘no-bid’ in today’s market,” Bradford said in a note. Much-needed cash may be generated with the sale of its Russian and Kazakhstan pressure pumping business, which analysts said could fetch between $50 million and $200 million. The company would not divulge details on the unsolicited offer, nor a timeline of when a possible deal could be concluded. “We believe the most likely buyer is Rosneft and Trican is likely to realize cash proceeds of $175 million-$200 million in the context of the current market,” CIBC’s Morrison said, based on the assumption that 85 per cent of the $242 million generated from Trican’s international business is estimated to be from the region. Industry indicators suggest more pain is on the way for oilfield services companies. “The full impact of throttled back E&P spending was felt in April, with wells drilled and completions down 62 per cent and 74 per cent year-on-year, respectively,” said Dan MacDonald, analyst at RBC Dominion Securities Inc. Well completions were down 74 per cent in April year-on-year, fracturing-intensive gas well completion activity was down 51 per cent versus last year, and oil well completions were down 80 percent. Trican peer Ensign Energy Services Inc. recently described the upcoming summer in Canada as “very tough” and said it expects to use only a fourth of its equipment. Meanwhile, Precision Drilling Corp. has negotiated relief for the two principal covenants of its revolving credit facility. “We are entering a cyclical downturn that will parallel 2009 and in some cases, will be worse than 2009,” Morrison said. “First quarter was the start and Q2 will be much worse while Q3 and Q4 will be depend on commodity prices getting better.”Responding to Simkulet's objections to the two tragedies argument. The two tragedies argument (2TA) has been raised as a response to the argument against abortion from spontaneous abortion (or miscarriages). According to this argument against the antiabortion position (AAP), miscarriages should be of great concern for proponents of this position since they result in a greater amount of deaths of human beings than induced abortions do. According to critics of AAP, this fact undermines its plausibility, since proponents of the AAP either must try to prevent miscarriages to the same extent as they try to prevent abortions or abandon their opposition to at least some abortions-which are not acceptable options for proponents of APP. The claim of 2TA is that one can differentiate between induced abortion and miscarriages due to the fact that the former involves the act of killing of another human being. This fact adds a tragedy to the tragedy that both abortions and miscarriages result in - the death of a human being - and contributes to justifying the choice of proponents of AAP to prioritise the prevention of abortions rather than miscarriages. In this response, I defend 2TA against criticism that claims that this argument is: (1) inconsistent with the AAP and (2) trivialises the death of the fetus. My claim is that the first line of criticism rests on a misunderstanding of the premises of 2TA while the second line of criticism rests on a disanalogous thought experiment. I therefore conclude that these objections fail.Q: Airflow ExternalTaskSensor execution timeout I'm using airflow.operators.sensors.ExternalTaskSensor to make one Dag wait for another. dag = DAG( 'dag2', default_args={ 'owner': 'Me', 'depends_on_past': False, 'start_date': start_datetime, 'email': ['[email protected]'], 'email_on_failure': True, 'email_on_retry': False, 'retries': 2, 'retry_delay': timedelta(minutes=10), }, template_searchpath="%s/me/resources/" % DAGS_FOLDER, schedule_interval="{} {} * * ".format(minute, hour), max_active_runs=1 ) wait_for_dag1 = ExternalTaskSensor( task_id='wait_for_dag1', external_dag_id='dag1', external_task_id='dag1_task1', dag=dag ) If something seriously wrong happens with upstream Dag and it fails to complete during the given time period, I want upstream Dag (ExternalTaskSensor operator) crash as well, instead of hanging forever. How can I add a timeout to ExternalTaskSensor? I'm looking into documentation, but it does not seem to have a timeout parameter or something similar. What should I do? https://airflow.readthedocs.io/en/stable/_modules/airflow/sensors/external_task_sensor.html A: The ExternalTaskSensor does take a timeout argument in seconds. It inherits the argument from BaseSensorOperator (https://airflow.apache.org/_modules/airflow/sensors/base_sensor_operator.html). If you pass it timeout=60 on instantiation, it will fail after 60 seconds. /--------------------------------- C++ -----------------------------------\ \| ========= \| \| \| \\ / F ield \| OpenFOAM: The Open Source CFD Toolbox \| \| \\ / O peration \| Version: 2.3.0 \| \| \\ / A nd \| Web: www.OpenFOAM.org \| \| \\/ M anipulation \| \| \---------------------------------------------------------------------------/ FoamFile { version 2.0; format ascii; class volScalarField; location "0"; object Ydefault; } // * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * // dimensions [0 0 0 0 0 0 0]; internalField uniform 0.0; boundaryField { fuel { type fixedValue; value uniform 0.0; } air { type fixedValue; value uniform 0.0; } outlet { type inletOutlet; inletValue uniform 0.0; value uniform 0.0; } frontAndBack { type empty; } } // ************************************************************************* // ``defined`` =========== ``defined`` checks if a variable is defined in the current context. This is very useful if you use the ``strict_variables`` option: .. code-block:: twig {# defined works with variable names #} {% if foo is defined %} ... {% endif %} {# and attributes on variables names #} {% if foo.bar is defined %} ... {% endif %} {% if foo['bar'] is defined %} ... {% endif %} When using the ``defined`` test on an expression that uses variables in some method calls, be sure that they are all defined first: .. code-block:: twig {% if var is defined and foo.method(var) is defined %} ... {% endif %} Q: Android : How to stop all threads start in fragment when change fragment I have an activity with many fragments inside. In one fragment, I run some periodically thread that use some command such as getActivity().runOnUiThread(), so when switch to different fragmemnt, those statement will make NullPointException. I know how to stop a thread, but don't know which method to put this code inside. (it means: when switch fragment, which method that fragment will always run before switch). Please help me about this problem. Thanks :) A: Thanks to help of Leco. The best way is put those code into onPause. You can see more detail in this link: Fragment Lifecycle Help this post will useful for anyone meets same problem with me. Q: Are the total false positives and false negatives of
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2306, 74, 92, 37, 13879, 2306, 74, 10, 43, 64, 83, 393, 5786, 500, 578, 83, 64, 17, 10878, 6915, 247, 11276, 7466, 1008, 44, 6453, 6759, 268, 15, 1348, 1092, 1764, 2043, 92, 2132, 94, 187, 50274, 1035, 3214, 578, 89, 64, 74, 2306, 19, 36341, 37, 18914, 2306, 74, 92, 37, 13879, 2306, 74, 10, 43, 64, 83, 9, 89, 10, 187, 50274, 8114, 393, 1124, 92, 18, 1217, 23, 2386, 3442, 1269, 7294, 19, 889, 565, 64, 17, 19022, 3442, 1269, 4935, 91, 14, 2386, 3442, 1269, 599, 4800, 20, 61, 3214, 578, 89, 64, 74, 2306, 21, 43, 64, 83, 9, 89, 64, 74, 559, 187, 50274, 91, 13941 ]	\int_{\mathbb{R}}\nabla \rho_{{\varepsilon},r,r_0} \cdot (2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta.$$ Then there exists a constant $C = C(d,J)$ such that $${\left\\|U\right\\|}_{L^1(\Pi_T^{r_0})} \le C\frac{{{\Delta x}}^2}{r^3}\left(1 + \frac{{{\Delta x}}}{r}\right){\left\\|A(u_{{\Delta x}})\right\\|}_{L^1([0,T];BV({\mathbb{R}}^d))}.$$ The $BV$ norm may be replaced by the $L^1$ norm at the expense of an extra factor $r^{-1}$. Clearly, $$\begin{gathered} {\left\\|\int_{\mathbb{R}}\nabla \rho_{{\varepsilon},r,r_0} \cdot (2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta\right\\|}_{L^1(\Pi_T^{r_0})} \\ \le {\left\\|\nabla \rho_{{\varepsilon},r,r_0}\right\\|}_{L^\infty(\Pi_T^{r_0} \times {\mathbb{R}};{\mathbb{R}}^d_\infty)}{\left\\|(2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\\|}_{L^1(\Pi_T^{r_0} \times {\mathbb{R}};{\mathbb{R}}^d_1)}. \end{gathered}$$ By Young’s inequality for convolutions, $$\begin{aligned} {\left\\|\partial_{x_i}\rho_{{\varepsilon},r,r_0}\right\\|}_{L^\infty(\Pi_T^{r_0} \times {\mathbb{R}})} &\le {\left\\|\chi(A(u);\cdot)\right\\|}_{L^\infty(\Pi_T \times {\mathbb{R}})}{\left\\|J_{\varepsilon}\otimes \partial_{x_i}J_r \otimes J_{r_0}\right\\|}_{L^1({\mathbb{R}}\times {\mathbb{R}}^d \times {\mathbb{R}})} \notag \\ &\le {\left\\|\partial_{x_i}J_r\right\\|}_{L^1({\mathbb{R}}^d)} \le 2{\left\\|J'\right\\|}_\infty r^{-1}. \end{aligned}$$ We have $$(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (2\partial_{x_i} -({D_+}^i + {D_-}^i))J_r \otimes J_{r_0}.$$ Using Taylor expansions with remainders, $$\begin{aligned} \left(({D_+}^i + {D_-}^i)-2\partial_{x_i}\right)J_r(x) &= \frac{1}{2{{\Delta x}}} \int_0^{{{\Delta x}}}(z-{{\Delta x}})^2 \partial_{x_i}^3J_r(x_i+z)\,dz \,\prod_{j \neq i}J_r(x_j) \\ &\qquad + \frac{1}{2{{\Delta x}}} \int_{-{{\Delta x}}}^0(z+{{\Delta x}})^2 \partial_{x_i}^3J_r(x_i+z)\,dz \,\prod_{j \neq i}J_r(x_j) \\ &=: \partial_{x_i}(\varphi^i_1(x) + \varphi^i_2(x)), \end{aligned}$$ see for instance [@KRS2014 p. 25]. Hence $$(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \partial_{x_i}\left(\chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (\varphi^i_1 + \varphi^i_2) \otimes J_{r_0}\right).$$ By Young’s inequality for convolutions $$\begin{gathered} {\left\\|(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\\|}_{L^1(\Pi_T^{r_0} \times {\mathbb{R}})} \le {\left\\|\chi(A(u_{{\Delta x}});\cdot)\right\\|}_{L^1([0,T] \times {\mathbb{R}};BV({\mathbb{R}}^d))}\\ \times {\left\\|\varphi^i_1 + \varphi^i_2\right\\|}_{L^1({\mathbb{R}}^d)}. \end{gathered}$$ Note that ${\left\\|\chi(A(u_{{\Delta x}});\cdot)\right\\|}_{L^1([0,T] \times {\mathbb{R}};BV({\mathbb{R}}^d))} = {\left\\|A(u_{{\Delta x}})\right\\|}_{L^1([0,T];BV({\mathbb{R}}^d))}$. Now, as $\partial_{x_i}J_r(x_i + z) \le r^{-3} {\left\\|J''\right\\|}_\infty{\mathds{1}_{{\left\|x_i+ z\right\|} \le r}}$, it follows that $$\begin{aligned} {\left\\|\varphi^i_1\right\\|}_{L^1({\mathbb{R}}^d)} &= \frac{1}{2{{\Delta x}}}\int_{\mathbb{R}}\Bigl\|\int_0^{{{\Delta x}}}(z-{{\Delta x}})^2 \partial_{x_i}^2J_r(x_i+z)\,dz\Bigr\|\, dx_i \\ &\le \frac{(r + {{\Delta x}})}{{{\Delta x}}r^3}{\left\\|J''\right\\|}_\infty\int_0^{{{\Delta x}}}(z-{{\Delta x}})^2\,dz \\ &\le \frac{1}{3}{\left\\|J''\right\\|}_\infty \frac{{{\Delta x}}^2}{r^2}\left(1 + \frac{{{\Delta x}}}{r}\right). \end{aligned}$$ The same estimate applies to $\varphi_2^i$. \[est:5\] Let ${\mathscr{T}}$ be the term from Lemma \[lemma:ContractionLemma\], that is, $${\mathscr{T}}= \int_R ({\mathrm{sign}_\varepsilon\left(\zeta-A(u)\right)} \star J_{r_0} \otimes J_r)(\Delta - {D_-}\cdot {D_+})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta.$$ Then there exists a constant $C = C(d,J)$ such that $${\left\\|{\mathscr{T}}\right\\|}_{L^1(\Pi_T^{r_0})} \le C\frac{{{\Delta x}}^2}{r^3}\left(1 + \frac{{{\Delta x}}}{r}\right){\left\\|A(u_{{\Delta x}})\right\\|}_{L^1([0,T];BV({\mathbb{R}}^d))}.$$ At the cost of an extra factor $r^{-1}$, the $BV$ norm may be replaced by the $L^1$ norm. First note that ${\left\|{\mathrm{sign}_\varepsilon\left(\zeta-A(u)\right)} \star J_{r_0} \otimes J_r\right\|} \le 1$, so $${\left\|{\mathscr{T}}\right\|} \le {\left\\|(\Delta - {D_-}\cdot {D_+})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\\|}_{L^1(\Pi_T \times {\mathbb{R}})}.$$ Now, $$(\partial_{x_i}^2 - {D_-}^i{D_+}^i)\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (\partial_{x_i}^2 - {D_-}^i{D_+}^i)J_r \otimes J_{r_0}.$$ Using a Taylor expansion [@KRS2014 p.24], $$\begin{aligned} (\partial_{x_i}^2-{D_-}^i{D_+}^i)J_r(x) &= \frac{1}{6{{\Delta x}}^2}\int_0^{{\Delta x}}(z-{{\Delta x}})^3\partial_{x_i}^4J_r(x_i + z)\,
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8219, 326, 253, 1307, 346, 78, 12653, 3, 310, 594, 3862, 326, 352, 10949, 1142, 15991, 534, 253, 18818, 858, 417, 18607, 281, 3835, 285, 13, 3103, 13, 253, 17612, 23962, 253, 7289, 285, 10023, 273, 13717, 310, 594, 44245, 326, 352, 10224, 281 ]	in order to perform the task by legislation. Moreover, the act sets forth in sufficient exactness the things to be considered by the Department in reaching its determinations. It sets forth just who shall be liable under the act and how the Department shall determine their liability. The act provides for an administrative hearing at the instance of any person affected or aggrieved by the administration of the act, and allows judicial review under the Administrative Review Act of any final decision of the Department. (See Sheldon v. Hoyne, 261 Ill. 222.) The discretion allowed the Department is therefore far from arbitrary, being subject to all these limitations, rules, and provisions of law. 422 After a careful examination of sections 19 to 25 of article IX, inclusive, of the Mental Health Code, we are of the opinion that none of these sections are vulnerable to the constitutional objections advanced and that the superior court of Cook County erred in holding those sections of the statute unconstitutional and in enjoining their enforcement. The decree of the superior court of Cook County is therefore reversed and the cause is remanded, with directions to vacate the decree heretofore entered and to dismiss plaintiffs' suit for want of equity. Reversed and remanded, with directions. Mr. JUSTICE SCHAEFER took no part in the consideration or decision of this case. Effect of nonspecific interactions of the hepatitis B surface antigen with the solid phase on its detection by two-site immunoradiometric assay. Two-site immunoradiometric assay (Austria II-125, procedure B, Abbott) was used to detect hepatitis B surface antigen (HBsAg) in chronic carrier sera from clinically healthy subjects or from kidney transplant or hemodialysis patients. The titration curves of some high-titered sera showed a prozone-like effect; this corresponded in two such sera LB and MA, to congruent to 80% inhibition of HBsAg detection in undiluted serum relative to a 1:800 dilution. The nature of the inhibition in the above two sera was investigated. We found that the inhibition depended on the time of first incubation but not on the affinity of capture antibodies. Nonspecific adsorption of HBsAg to the solid phase during the first incubation with inhibitory sera and elution of the thus adsorbed antigen during the second incubation, with the resulting neutralization of 125I-labeled anti-HBs, appeared to cause the inhibition of detection observed. The inhibition was prevented by addition of the detergent Triton X-100 to serum or by elution of adsorbed antigen prior to the second incubation, thus indicating that further improvements of the HBsAg immunoradiometric assay may be possible. 239 A.2d 215 (1968) The STATE of Delaware v. Willle Lee JACKSON. Superior Court of Delaware, New Castle. February 16, 1968. 216 Francis A. Reardon, Deputy Atty. Gen., for the State. Henry A. Wise, Jr., Wilmington, for defendant. OPINION CHRISTIE, Judge. The defendant was arrested for the possession and sale of marijuana following the search of his premises pursuant to a search warrant. Thereafter, the defendant was indicted for the sale and possession of "a narcotic drug, to-wit: Marijuana" in violation of 16 Del.C. § 4702(a). Subsequently, the defendant moved to suppress the evidence obtained by the search warrant on the ground that the warrant authorized a search for narcotic drugs and the return showed marijuana had been seized, which defendant contends is not a narcotic drug. The defendant also moved to dismiss the indictment on two grounds: 1) the statute under which the indictment was brought is unconstitutional in that it includes in the body a subject not set forth in the title of the act in violation of Article 2, Section 16 of the Delaware Constitution, Del. C.Ann. and, 2) the indictment failed to advise the defendant of the offense charged because the statute on which it is based prohibits the sale and possession of many substances the legislature did not intend to prohibit. The statute under which the defendant was indicted is 16 Del.C. § 4702(a). This Section was originally enacted as a part of the Delaware Narcotic Drug Act adopted on April 18, 1935 as 40 Del.Laws Ch. 225. The title of the Narcotic Act read in pertinent part: "An Act Defining and Relating to Narcotic Drugs and the use thereof Regulating and Prohibiting the Manufacture, Possession, Control, Sale; * * ." The body of the act when enacted and as reenacted in the Code in 1953 defines marijuana as a narcotic drug. The defendant contends the above quoted title is unconstitutional because it violates Article 2, Section 16 of the Delaware Constitution which provides that: "No bill or joint resolution except bills appropriating money for public purposes, shall embrace more than one subject, which shall be expressed in its title." Defendant's contention is that marijuana is not a narcotic drug, and therefore, is not a subject which can be included within the statute, the title of which indicates that narcotics is the subject dealt with. The first question is whether the defendant may properly challenge the constitutionality of a title to an act the provisions of which were subsequently reenacted as part of the Delaware Code. Such a challenge has been entertained but only in cases where the significance of the reenactment as part of the Delaware Code was not raised or decided. Randolph v. Wilmington Housing Authority, 37 Del.Ch. 202, 139 A. 2d 476 (1958), State of Delaware v. Chase, 11 Terry 383, 131 A.2d 178 (1957). The title of the act by which the Delaware Code was adopted in 1953 has been held to be sufficient to meet the constitutional requirements of Article 2, Section 16 of the State Constitution. Monacelli v. Grimes, 9 Terry 122, 99 A.2d 255 (1953). The title of the act adopting the Delaware Code necessarily covers the statutes, acts and laws included therein at the date of its adoption. Since the title of the Delaware Code is adequate for the entire Code and meets constitutional requirements an attack on the validity of a title of an act which was reenacted as part of the Delaware Code is futile. State v. Durham, Del.Super., 191 A.2d 646 (1963). If the defendant were permitted to attack the title of an act which was enacted prior to the Delaware Code and later reenacted as a part thereof, an issue then might arise as to whether the title was 217 adequate. This in turn might depend on whether or not marijuana is a narcotic drug within the accepted meaning of the term. Questions similar to this have been raised in other jurisdictions which, like Delaware, have included provisions as to marijuana in their narcotic laws. Wherever the issue has been raised it has been held in effect that marijuana is a narcotic drug for purposes of statutory interpretation. Spence v. Sacks, 173 Ohio St. 419, 183 N. E.2d 363 (1962); People v. Stark, 157 Colo. 59, 400 P.2d 923 (1965); Commonwealth v. Leis and Weiss, Mass.Superior Court No. 28841-1 (1967); Gonzales v. State, 163 Tex.Cr.R. 432, 293 S.W.2d 786 (1956); People v. Rumley, 100 Cal.App.2d 6, 222 P.2d 913 (1950); Escobio v. State, Fla., 64 So.2d 766 (1953). Under Delaware decisional law, the constitutional provision in question does not require the title of a new statute to go into details or to furnish an abstract, synopsis, or index of the contents of the act. Monacelli v. Grimes, supra. The constitutional requirement is satisfied if the title is sufficiently informative so as to put on notice parties interested in the general matter in such a manner as would lead them to inquire into it. In Re Opinion of the Justices, 4 Storey 366, 177 A.2d 205 (1962). The portion of the title of the narcotics law, quoted above, was sufficiently informative so as to lead interested persons to inquire into the full details of the act. I am of the opinion that the Delaware Narcotics Law satisfies the requirements of Article 2, Section 16 of the State Constitution even before it was reenacted as part of the Delaware Code. There is still a third reason why the defendant cannot prevail in his attack on the title of the original act. The title includes notice that the term "narcotic drugs" is defined therein. With such notice in the title the legislature is especially free to define the term differently than might be the usual definition of such term. In this act the legislature went on to provide that "`narcotic drugs' means * * * marihuana, marijuana, and all allied drugs of the same botanical family * * *." Defendant's motion to dismiss the indictment based on the contention that the title of the underlying act is constitutionally deficient is denied. The next question is whether the indictment advised the defendant of the offense with which he is charged. Under Criminal Rule 7(c), Del.C. Ann., an indictment must contain a plain, concise written statement of the essential facts constituting the offense charged. The indictment must apprise the defendant with such detail as to enable him to prepare his defense and to plead the proceeding as a bar to a second prosecution for the same offense. Demonia v. State, Del., 210 A.2d 303 (1965). The defendant argues that the term "marijuana" is so broad that it covers many substances which the legislature did not intend to cover and, therefore, the indictment alleging the sale and possession of marijuana is so indefinite that it fails to
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22826, 1495, 4245, 441, 767, 1841, 27, 581, 13, 253, 3745, 281, 8027, 15832, 285, 5580, 352, 432, 8852, 281, 8852, 347, 1199, 347, 359, 476, 28, 285, 767, 13, 281, 9569, 747, 9050, 273, 8463, 275, 26020, 326, 4390, 1053, 457, 85, 452, 731, 1806 ]	the district court’s denial of his motion for a new trial pursuant to Rule 33 of the Federal Rules of Criminal Procedure. We are not persuaded. We review a district court’s disposition of a motion for new trial for abuse of discretion. See United States v. Martinez, 763 F.2d 1297, 1312 (11th Cir. 1985). “On a motion for a new trial based on the weight of the evidence, the court need not view the evidence in the light most favorable to the verdict. It may weigh the evidence and consider the credibility of the witnesses.” Id. Motions for a new trial 11 Case: 15-11695 Date Filed: 04/12/2016 Page: 12 of 13 are granted sparingly and only for an exceptional case. See id. A new trial for example, may be the appropriate remedy when the government’s witnesses have been severely impeached and the government’s case has been marked by discrepancies. See id. This is not an exceptional case, and the weight of the evidence presented did not warrant granting Mr. Brooks a new trial. The government’s witnesses were not impeached. The government’s case was circumstantial, but it was not marred by discrepancies. Mr. Brooks’ competing theory that his son or someone else repeatedly downloaded the child pornography and refined the files over time was heard and rejected by the jury. Mr. Brooks’ alternative theory did not present any discrepancies in the government’s case; it simply presented a different view of the facts and attempted to shift the blame to someone else. Although it did provide a counter weight to the evidence put forward by the government, it did provide enough weight to warrant a reversal of the district court’s denial of a motion for new trial. In sum, the district court did not abuse its discretion in denying Mr. Brooks a new trial. The evidence presented at trial did not preponderate heavily against the guilty verdicts, such that to let them stand would be a miscarriage of justice. See Martinez, 763 F.2d at 1313. 12 Case: 15-11695 Date Filed: 04/12/2016 Page: 13 of 13 VI We affirm Mr. Brooks’ convictions. AFFIRMED 13 Photos by Jun Cayas “You have so much here. You just have to come together.” - Charlie Co Who would have thought what three days with multiple artists coming from the different parts of the country could bring? It all…Q: Moq test passes even when verifying both Times.Once() and Times.Never() on same method call I'm using Xunit to test the Create method on my CarController and I'm using Moq to mock my CarRepository. I'm then using mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Once()); to check that the Create method on my repository is being called. However the test passes irrespective of whether I call it or not. Here is a complete example where I verify both that Create is called once AND that it is called never. My test passes when I would have expected it to fail. using System; using Moq; using Xunit; namespace Test { public class CarTest { [Fact()] public async void CreateTest() { var mockCarRepository = new Mock<CarRepository>(); var carController = new CarController(mockCarRepository.Object); carController.Create(new Car { Make = "Aston Martin", Model = "DB5" }); mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Once()); mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Never()); } } public class CarController { private readonly CarRepository _repo; public CarController(CarRepository repo) { _repo = repo; } public void Create(Car car) { _repo.Create(car); } } public class Car { public virtual String Make { get; set; } public virtual String Model { get; set; } } public class CarRepository { public virtual void Create(Car car) { // DO SOMETHING } } } When I debug the test, although it still passes, I notice that the following exception is thrown: A first chance exception of type 'Moq.MockException' occurred in Moq.dll Additional information: Expected invocation on the mock should never have been performed, but was 1 times: m => m.Create(It.IsAny<Car>()) No setups configured. Performed invocations: CarRepository.Create(Test.Car) The exception is expected as I am calling Create once and verifying Times.Never() but I would like my test to fail. What do I need to do to achieve this? Update It turns out that the problem was that I'd marked my test as async - removing that causes it to pass. However the actual code I'm writing will call an async method, so my question is now, how can I verify methods are called when using asynchronous methods? A: See the answer here for an explanation of why async void test methods do not work in xUnit. The solution is to give your test method an async Task signature. async void functionality has been added ready for version 2.0 of xunit, see here for details. The series: We look at manufacturing companies that are using technology to create “smart factories” fit for long-term global competitiveness. Open this photo in gallery Parmalat Canada has retooled its factories to bottle milk in new, recyclable,1.5-litre bottles made of polyethylene terephthalate (PET). They keep milk fresher for a longer period of time. Handout/Lactancia Regular, unadorned milk remains a staple, and that’s part of a problem. “Don’t mess with my milk, don’t change it,” said Marco De Palma, lamenting the typical consumer perception in Canada. Story continues below advertisement Canadians tend to see milk as fresh, unchanged, sacrosanct, but then they look for other beverages when they get bored with it. So, as general manager of fluid milk and distributor sales at Parmalat’s office in Toronto, Mr. De Palma wants to – in fact needs to – make milk more exciting, as does the rest of the industry. Innovation means bringing in new manufacturing methods, new milk flavours, new formulas into a sector that’s aging and somewhat stuck in the past. Made all the more difficult by a product that spoils so quickly. But innovation is happening, because it has to, industry watchers say. Overall milk consumption continues to decline. Almond and soy drinks continue to siphon off customers. The usual link between milk consumption and demographics – that is, when the population rises, overall milk consumption typically rises – has weakened, some note. Many new Canadians may more readily reach for a glass of yogurt-based lassi or a salty, yogurty ayran. And among those consumers buying milk regularly, alternatives such as lactose-free milk are stealing away customers, in this age of growing dietary intolerance. “There is a mix of what people are buying, but overall consumption is still in decline,” Mr. De Palma said. To stem this drop, Parmalat Canada, a subsidiary of Parmalat SpA of Italy, has launched a new plastic bottle for its Lactania PurFiltre brand. This may hardly seem revolutionary, but for Parmalat, it’s a step within a larger strategy. The bottles' size (1.5 litres) is out of the norm, different than regular one- or two-litre cartons, or bags and common milk jugs. They’re made of polyethylene terephthalate (PET) rather than the usual high density polyethylene (HDPE) for plastic jugs, with a bottle shape designed to make it look unlike other milk bottles on the dairy shelf. This, of course, entailed equipping plants with new machinery and production methods, including equipment that can handle other kinds of milk processing, which can give the milk a longer shelf life. Parmalat hopes that the new-look, PET bottles, which are recyclable and BPA free, are a step in keeping milk fresher, longer, broadening its reach into new markets. Story continues below advertisement “Those bottles will have 60 days of shelf life after production, compared to a carton which hovers between 39 to 50 days, depending on the product. That shelf life gives us two things: one, the ability to launch innovation and sell it from coast to coast as much as we can; and two, to introduce new categories of milk in provinces that currently don’t have them,”
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9054, 4343, 457, 985, 13, 978, 3867, 773, 44757, 5948, 668, 1411, 616, 36491, 275, 253, 1416, 273, 773, 13961, 3570, 1806, 533, 323, 253, 5649, 273, 253, 8628, 7961, 266, 13001, 285, 5213, 18674, 15, 1893, 352, 369, 342, 253, 8365, 10039, 390, 342, 253, 7057, 31945, 15, 187, 187, 47, 10993, 84, 27312, 342, 6086, 24367, 375, 285, 643, 4083, 4670, 285, 1227, 390, 14597, 407, 253, 1982, 4487, 273, 2418, 452, 9009, 253, 11595, 84, 273 ]	Biography Channel, NBC and more. He also wrote and directed two sold-out 2014 BroadwayWorld charity concert events featuring all-star casts, EVERYTHING'S COMING UP BROADWAYWORLD.COM: A JULE STYNE TRIBUTE and THE LORD & THE MASTER: BROADWAYWORLD.COM SINGS THE MUSIC OF ANDREW LLOYD WEBBER & STEPHEN SONDHEIM.namespace CruiseControl.Common { using System.Runtime.Serialization; /// <summary> /// The arguments for a query. /// </summary> [DataContract] public class QueryArguments { #region Constructors /// <summary> /// Initializes a new instance of the <see cref="QueryArguments"/> class. /// </summary> public QueryArguments() { this.DataToInclude = DataDefinitions.Both; } #endregion #region Public properties #region FilterPattern /// <summary> /// Gets or sets a REGEX pattern for filtering the actions. /// </summary> /// <value> /// The filter pattern. /// </value> [DataMember] public string FilterPattern { get; set; } #endregion #region DataToInclude /// <summary> /// Gets or sets the data to include. /// </summary> /// <value> /// The data to include. /// </value> [DataMember] public DataDefinitions DataToInclude { get; set; } #endregion #endregion } }Q: How can I pass data from another class to a GUI? How do I pass data/values from one class to another using GUI? I'm trying to pass the message2 array to namesOut label in GUI. I'm stuck and getting an error. Here's my code: GUI package testClassesGUI; import java.awt.BorderLayout; public class UI extends JFrame { private JPanel contentPane; /** * Launch the application. / public static void main(String[] args) { EventQueue.invokeLater(new Runnable() { public void run() { try { UI frame = new UI(); frame.setVisible(true); } catch (Exception e) { e.printStackTrace(); } } }); } /* * Create the frame. */ public UI() { setDefaultCloseOperation(JFrame.EXIT_ON_CLOSE); setBounds(100, 100, 450, 300); contentPane = new JPanel(); contentPane.setBorder(new EmptyBorder(5, 5, 5, 5)); setContentPane(contentPane); contentPane.setLayout(null); JLabel lblDisplayOutNames = new JLabel("Display out names:"); lblDisplayOutNames.setBounds(32, 25, 121, 16); contentPane.add(lblDisplayOutNames); JLabel namesOut = new JLabel(""); //here i need to bring the data namesOut.setBounds(32, 63, 228, 87); contentPane.add(namesOut); } } Logic: Here I'm getting an error. package testClassesGUI; public class Logic { private String[] someArray = { "Great", "World" }; // getter method public String[] message2(){ return someArray; } // setter method public void setSomeArray(String[] someArray){ this.someArray = someArray; } UI logicObject = new UI(); logicObject.namesOut.setText(message2); //here my error misplaced construct(s), variable declaratoridexpected } Your help is much appreciated. A: Put this in your UI constructor. You should create a Logic object in it public UI() { setDefaultCloseOperation(JFrame.EXIT_ON_CLOSE); setBounds(100, 100, 450, 300); contentPane = new JPanel(); contentPane.setBorder(new EmptyBorder(5, 5, 5, 5)); setContentPane(contentPane); contentPane.setLayout(null); JLabel lblDisplayOutNames = new JLabel("Display out names:"); lblDisplayOutNames.setBounds(32, 25, 121, 16); contentPane.add(lblDisplayOutNames); JLabel namesOut = new JLabel(""); //here i need to bring the data namesOut.setBounds(32, 63, 228, 87); contentPane.add(namesOut); Logic logic = new Logic(); <<--- String[] array = logic.message2(); \| \| String s = ""; \| for (String str : array){ \| s += str + " "; \| } \| \| namesOut.setText(s); <<---- } You can delete this from your Logic class UI logicObject = new UI(); logicObject.namesOut.setText(message2); International NGOs are instruments of cultural imperialism RIO DE JANEIRO, Brazil – In developing or underdeveloped countries (in Latin America, Africa, Asia and parts of Eastern Europe), the participation of NGOs in the provision of basic public services is increasing. They aim to replace weak and/or poor states in various resource-poor sectors. Some of these NGOs are also involved in state oversight, supposedly in favor of “human rights.” It is easy to point out fundamental problems in these NGOs. States are accountable to their citizens. If their governments fail to live up to the expectations of the masses, they risk being traded or, in more drastic cases, even toppled by an angry population. Who do NGOs respond to? Just to your donors, usually wealthy citizens, foreign governments or powerful corporations. These NGOs pass on to their donors information (true or otherwise) on the beneficiaries to the donors, who then guarantee the donations. But understand: if NGOs succeed in solving the problems they care about, they simply will not be needed anymore. However, it is clear that NGOs will not disappear, and that they do not exist to solve definitively the problems of their interest. The phenomenon of NGOs has exploded since the 1980s, being born in the rich countries of the first world, for very clear reasons. In the global capitalist elite there are distinct degrees of intelligence and sensitivity, and among them a more perceptive layer noted that the implementation of neoliberalism was polarizing societies and generating strong social commotion. Neoliberal politicians, entrepreneurs, and bankers then began to finance and promote a “bottom-up” parallel strategy, with organizations driven by an “anti-statist” ideology whose aim was to appease the masses and at the same time , to promote the dismantling of the state and to demobilize serious political and social organizations. In the 1990s, these NGOs were already thousands and moving around $ 4 billion worldwide every year. One of its main sources of funding has been the World Bank. The point of convergence between interests is clear: NGOs criticize the state from a progressive left-wing perspective, in defense of a supposed civil society, while the right wing does it in defense of the market. In other words, as neo-liberal regimes devastated their own countries and foreign countries, flooding them with cheap imports, crushing them with usurious debts, abolishing labor laws and creating a growing mass of precarious workers, NGOs assumed the role of “self-help” to local communities, deviating from any kind of radical political and social militancy. NGOs, in this sense, are nothing more than a “communal” face of neoliberalism. They are financed by the same characters that cause the problems they are aiming to fight. In this sense, they play a fundamentally depoliticizing and relieving role. Its aim is not to solve problems, but to try to stifle conflicts and make capitalist exploitation more palatable. In this way, the very classification they lead is even fallacious. Considering that they receive funding from capitalist governments, and that they usually work with agencies and departments of these governments, it is not true that these institutions are effectively non-governmental. More recently, NGOs have taken an even more prominent role in the imperialist strategies of the globalist elite. “Human rights” NGOs infest countries considered enemies by the Atlantean governments. There, these NGOs work to undermine the institutional solidity of the enemy countries’ system, instilling “civil society” against their rulers in the name of “human rights,” but for the benefit of the Atlantean governments and international corporations. So it was with the Arab Spring or with the Maidan. NGOs affiliated with George Soros and other financiers and / or funded by the US Department of State have implemented the manuals of
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Romney and Obama have one more debate, on Monday at Lynn University in Boca Raton, Fla. Although the focus of the final forum is foreign policy, it will be a time for the candidates to make their closing arguments to try to woo undecided voters and motivate their respective bases, whose enthusiasm becomes crucial in a close contest. But after what happened at Hofstra, it’s clear that the real competition will be the fight to the finish, a battle for the battleground states where the election will be decided. The most important are Virginia, Florida and Ohio — with Ohio being perhaps first among equals. After that come Iowa, Colorado and New Hampshire, Nevada, North Carolina and Wisconsin. Few events have changed the race as quickly or dramatically as the first debate. Romney’s clear victory over Obama in Denver turned around the campaign narrative, which was heading toward a premature conclusion that the contest was virtually over. It also shifted polls, both nationally and in the battleground states. How many minds will be changed by what happened on Tuesday night? There is likely to be a boost in enthusiasm among Obama loyalists, and that’s not insignificant. Given that some parts of his coalition, young voters in particular, are not as motivated as they were four years ago, that jolt of energy could be important. Obama advisers know that turning out their voters will be harder for them than it will be for Romney’s team. But Romney’s initial performance did much to generate enthusiasm among his supporters. That’s not likely to be diminished by Tuesday’s debate. After Denver, Republicans began to think it was possible to win. Their enthusiasm going forward is unlikely to slacken. The turnout battle from now until Election Day will be as fiercely fought as was the battle at Hofstra. One of the keys to the outcome will be women, and a big question from Tuesday’s debate is how women will react to what they saw. Romney appeared to be making progress in reducing Obama’s big margins among female voters in the past two weeks. But he may have hurt himself. Just as Vice President Biden’s smiles and laughs during his debate with GOP vice presidential nominee Paul Ryan (Wis.) last week turned off some voters, Romney’s efforts to push back against CNN’s Candy Crowley, who served as moderator, could alienate some women. Heading into the second debate, there was little disagreement that a race that had seemed to be slipping away from Romney in September was back to what strategists in both parties had predicted would be a competitive contest to the end. In the hours before the exchange, the Romney and Obama campaigns offered genuinely conflicting and perhaps self-serving assessments of how things stood — in the battlegrounds and among key demographic groups. Take the state of play in Ohio. Before Denver, Obama had a clear and, in some polls, big lead. In a pre-debate appearance Tuesday in the spin room, Sen. Rob Portman (R-Ohio) told reporters that the race there was even. “Our own tracking indicates it’s a dead heat,” he said. Portman, who has played the president in Romney’s debate preparations, said that before Denver, the challenger was behind by “a big gap,” but added that Romney has made steady progress since then. “Frankly, it wasn’t just a bump after the debate.” Jim Messina, Obama’s campaign manager, offered a counterview. He said the first debate may have tightened the race, but added that the contest always was destined to close in the final month. He also said that Obama was still strong in the Midwest — Ohio, Iowa and Wisconsin. “We continue to have more pathways to 270 votes than Romney,” he said. “All of our pathways are still there. We are where we need to be.” What voters saw Tuesday night was just how big the choice will be in November. Romney and Obama painted dire pictures of what will happen if the other is elected in three weeks. Voters may have heard this before, but it was more sharply etched, with the candidates standing only a few feet apart, than in the television commercials or campaign appearances. Now the campaign turns to fundamentals — one more debate and then a sprint to Nov. 6. The race has been long and hard-fought, but Obama and Romney showed Tuesday night that they have plenty left for the final stretch, and their teams are ready for what comes next.s v prime? True Let w(t) = 6 - t*2 - 3 + 0 - 6t. Let o be w(-6). Suppose ob - b - 70 = 0. Is b prime? False Suppose -5999 + 2486 = -3n. Is n prime? True Suppose -3z + 13 = -8. Suppose -8 = -3s + z. Suppose 2n + sv - 305 = 0, -3n - 2v + 151 = -2n. Is n a composite number? True Suppose 0 = 33i - 28i - 2045. Is i composite? False Is 807/9 + 4/(-6) prime? True Let u(p) = p - 10. Let q be u(8). Is q/8 + (-269)/(-4) composite? False Is ((-2)/(-6))/((-23)/(-66171)) a composite number? True Let y be (-15)/(-6)8/10. Suppose 335 = -g + yg. Suppose -d + 6d - g = 0. Is d a prime number? True Suppose -3z = -5y - 64, -12 = -2z + z - 3y. Let u = z - -1. Is u prime? True Suppose -4r + 20 = 4. Is r prime? False Let c = 8 + -4. Suppose c = -4q - 0q. Is 0 + 64 + q prime? True Suppose 5z - 33 + 13 = 0, z - 3 = d. Is 2d/(-5)-145 composite? True Let d(x) = 3x*3 - 2x*3 + 0x - 5x + 0x + 4x2 + 2. Let z be d(3). Let y = -28 + z. Is y a composite number? True Let f = -219 + 364. Is f prime? False Let j(d) = -d3 + 7d*2 + 10d - 1. Let r be j(8). Is 522/r + 1/5 a composite number? True Suppose -d = -a - 4a + 23, -d - 5a = -27. Suppose -530 = -di - 0i. Suppose 0 = -4h + i - 81. Is h composite? True Let r(f) = f2 - 6f. Let g be r(6). Let h(t) = t + 4. Let y be h(g). Is 1/y - 210/(-24) prime? False Is (-1 - 0)/((-2)/(-53384)-4) composite? False Let c(v) = 9v*2 - 5v + 1. Is c(-5) composite? False Suppose -7n + 2n + 10 = 0. Suppose -no + 6 = -0o. Suppose 0a + 609 = oa. Is a prime? False Let z(b) = 14b2 + b + 1. Is z(-2) composite? True Let o = 6 - 2. Is 9177/49 + o/(-14) a prime number? False Let v = 244 - 165. Is v composite? False Let q = -9 + 14. Suppose 4 = i - m, 5i - 16 = m - 0. Suppose -267 = -3r + in, -r + qn = -3r + 150. Is r composite? True Suppose 0 = -4t - 5g - 11 + 34, -3 = -3t + g. Suppose 0 + t = s. Is ((-33)/s)/((-3)/4) composite? True Suppose 2o - m = 9, -3o + 7o - 3m = 19. Suppose -or - 68 + 304 = 0. Is r a prime number? True Let j be (3 - -15) + (-4)/2. Let w = j + -11. Suppose 147 + 8 = wz. Is z prime? True Let a = 717 + -304. Is a composite? True Suppose 0 = -12g + 16g - 2140. Is g prime? False Let j be 3/(-5) - (-39)/15. Suppose -p - ji = p - 114, 6 = -3i. Is p composite? False Let q = -4 - -4. Suppose -4k + k + 45 = q. Is k composite? True Suppose 4h + l - 395 = 3h, 0 = -4h + 4l + 1548. Is h a prime number? False Let y(d) = -d
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346, 39104, 4595, 19438, 8754, 3, 3572, 187, 50266, 92, 346, 19214, 995, 346, 615, 427, 16478, 77, 61, 86, 361, 70, 21, 1251, 3, 3572, 187, 50266, 92, 346, 7716, 995, 346, 22427, 83, 664, 70, 5173, 3, 3572, 187, 50266, 92, 346, 11236, 995, 346, 47, 554, 455, 3, 3572, 187, 50266, 92, 346, 10189, 995, 346, 47, 4411, 86, 3, 3572, 187, 50266, 92, 346, 9744, 995, 346, 24534, 489, 3, 3572, 187, 50266, 92, 346, 47, 59, 995, 346, 6560, 2327, 15235, 3, 3572, 187, 50266, 92, 346, 2277, 995, 346, 48, 1342, 3, 3572, 187, 50266, 92, 346, 4899, 995, 346, 49, 1136, 2902, 3, 3572, 187 ]	beijn-K\u00f6\u00df" }, { "CK", "de Kuuk-Enselle" }, { "CL", "Schiile" }, { "CM", "Kammeruhn" }, { "CN", "Schiina" }, { "CO", "Kolumbije" }, { "CP", "de Klipperton-Ensel" }, { "CR", "Kostarika" }, { "CU", "Kuba" }, { "CV", "de kapv\u00e4rdesche Enselle" }, { "CW", "Cura\u00e7ao" }, { "CX", "de Weihnaachs-Ensel" }, { "CY", "Z\u00fcppere" }, { "CZ", "de Tsch\u00e4schei" }, { "DE", "Do\u00fctschland" }, { "DG", "de Diego-Garcia-Ensel" }, { "DJ", "Dschibutti" }, { "DK", "D\u00e4nemark" }, { "DM", "Dominnika" }, { "DO", "de Dommenekaanesche Reppublik" }, { "DZ", "Alljeerije" }, { "EA", "Ze\u2019uta un Meliija" }, { "EC", "\u00c4kwador" }, { "EE", "\u00c4\u00dfland" }, { "EG", "\u00c4j\u00fcpte" }, { "EH", "W\u00e4\u00df-Sahara" }, { "ER", "\u00c4ritreja" }, { "ES", "Schpaanije" }, { "ET", "\u00c4ttijoopije" }, { "EU", "de Europ\u00e4jesche Unijon" }, { "FI", "Finnland" }, { "FJ", "de Fidschi-Endelle" }, { "FK", "de Falkland-Enselle" }, { "FM", "Mikroneesije" }, { "FO", "de F\u00e4rr\u00f6r-Enselle" }, { "FR", "Frankrisch" }, { "GA", "Jabuhn" }, { "GB", "Jruu\u00dfbrettannije" }, { "GD", "Jrenaada" }, { "GE", "Jeorrjije" }, { "GF", "Franz\u00fc\u00fcsesch Jujaana" }, { "GG", "J\u00f6\u00f6nsei" }, { "GH", "Jaana" }, { "GI", "Jibralltaa" }, { "GL", "Jr\u00f6hnland" }, { "GM", "Jambija" }, { "GN", "Jinneha" }, { "GP", "Juadelupp" }, { "GQ", "\u00c4quatorial Jineeja" }, { "GR", "Jriescheland" }, { "GS", "S\u00f6d-Jeorjie un de s\u00f6dlijje Botteramms-Enselle" }, { "GT", "Juwatemaala" }, { "GU", "Juham" }, { "GW", "Jinneha_Bi\u00dfau" }, { "GY", "Jujaana" }, { "HK", "Hongkong" }, { "HM", "de Heart Ensel un de McDonald-Enselle" }, { "HN", "Honduras" }, { "HR", "Krowazije" }, { "HT", "Ha\u2019itti" }, { "HU", "Unjann" }, { "IC", "de Kannaresche Enselle" }, { "ID", "Indoneesije" }, { "IE", "Irrland" }, { "IL", "I\u00dfra\u00e4l" }, { "IM", "de Ensel M\u00e4n" }, { "IN", "Indije" }, { "IO", "Brettesche Besezunge em indesche Oozejahn" }, { "IQ", "Irak" }, { "IR", "Persije" }, { "IS", "I\u00dfland" }, { "IT", "Itaalije" }, { "JE", "J\u00f6\u00f6seh" }, { "JM", "Jammaika" }, { "JO", "Jordaanije" }, { "JP", "Japan" }, { "KE", "Keenija" }, { "KG", "Kirrjiisije" }, { "KH", "Kambodscha" }, { "KI", "Kiribati" }, { "KM", "de Kommoore" }, { "KN", "Zint Kitts un Nevis" }, { "KP", "Nood-Koreja" }, { "KR", "S\u00f6d-Koreja" }, { "KW", "Kuweit" }, { "KY", "de Kaiman-Enselle" }, { "KZ", "Kassakstahn" }, { "LA", "La\u2019os" }, { "LB", "Lebbannon" }, { "LC", "de Ensel Zint-Lutscha" }, { "LI", "Lischteschtein" }, { "LK", "Sri Lanka" }, { "LR", "Libeerija" }, { "LS", "Lesooto" }, { "LT", "Littaue" }, { "LU", "Luxembursch" }, { "LV", "L\u00e4tland" }, { "LY", "Libbije" }, { "MA", "Marokko" }, { "MC", "Monakko" }, { "MD", "Moldaavije" }, { "ME", "et Monteneejro" }, { "MF", "de Zint-M\u00e4\u00e4tes-Ensel" }, { "MG", "Maddajaska" }, { "MH", "de Machschall-Enselle" }, { "MK", "Mazedoonije" }, { "ML", "Maali" }, { "MM", "Birma" }, { "MN", "Mongjolei" }, { "MO", "Makau" }, { "MP", "de n\u00f6\u00f6dlijje Marijanne-Enselle" }, { "MQ", "Machtinik" }, { "MR", "Mautitaanije" }, { "MS", "Mong\u00dferrat" }, { "MT", "Malta" }, { "MU", "Maurizijus" }, { "MV", "Mallediive" }, { "MW", "Malawi" }, { "MX", "M\u00e4xiko" }, { "MY", "Malaisije" }, { "MZ", "Mosambik" }, { "NA", "Namiibije" }, { "NC", "Neuschottland" }, { "NE", "Nijer" }, { "NF", "de Noofok-Ensel" }, { "NG", "Nikaraagua" }, { "NI", "Nikaraaguwa" }, { "NL", "de Nederl\u00e4ng" }, { "NO", "Norrweeje" }, { "NP", "Nepall" }, { "NR", "Nauru" }, { "NU", "Niue" }, { "NZ", "Neuseeland" }, { "OM", "Oman" }, { "PA", "Pannama" },
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841, 310, 7220, 36, 18, 13, 534, 31360, 247, 33809, 29362, 15, 9149, 533, 417, 25607, 15814, 247, 13009, 32190, 275, 436, 3320, 13, 534, 26586, 253, 1390, 767, 562, 273, 1249, 8131, 33809, 15206, 265, 273, 253, 2601, 313, 7510, 73, 1109, 1136, 1162, 355, 904, 4072, 481, 831, 12955, 310, 1929, 281, 4796, 894, 14, 936, 14, 3992, 13099, 313, 263 ]	Isolated trans-acting loci that affect the expression of one or a few genes appear to be uncommon. Locations of eQTLs in the genome. (A) Map of local and distant eQTLs. The genomic locations of eQTL peaks (x-axis) are plotted against the genomic locations of the genes whose expression they influence (y-axis). The strong diagonal band corresponds to local eQTLs. The many vertical bands correspond to eQTL hotspots. Point size is scaled as a function of eQTL effect size, measured in fraction of phenotypic variance explained. (B) The number of gene expression traits linking to each of 102 identified eQTL hotspots (Methods) are shown as vertical bars. Text labels identify genes in hotspots referred to in the text. The 102 hotspots affected a median of 425 genes, ranging from 26 (a newly discovered hotspot at position 166,390 bp on chromosome III) to 4594 at the previously reported MKT1 hotspot (Zhu et al., 2008) (82% of 5629 genes with any signal at a hotspot; Figure 3B). Three additional hotspots each affected more than half of all genes. They include a previously described hotspot at the HAP1 gene (Brem et al., 2002) (3640 genes affected), as well as two newly detected hotspots on chromosome XIV. A hotspot at 372,376 bp affected 4172 genes and is likely caused by a variant that recently arose in the KRE33 gene in the RM parent used in our cross (Jerison et al., 2017). A hotspot at position 267,161 bp affected 3169 genes and spans the genes GCR2, YNL198C, WHI3 and SLZ1. These results indicate that hotspots can have extraordinarily wide-reaching effects on the transcriptome, with some influencing the expression of the majority of all genes. Widespread effects caused by single loci likely arise from a cascade of effects in which strong primary effects spread through the cellular regulatory network. For example, the BY allele of the transcriptional activator HAP1 carries a transposon insertion that reduces HAP1 function. As expected, the BY allele strongly reduced the expression of known transcriptional targets of HAP1: 26 out of the 69 HAP1 targets present in our data were among the 50 genes with the largest reduction in expression in segregants carrying the BY allele of HAP1 (p<2.2e-16, odds ratio = 138). In total, only 75 direct transcriptional HAP1 targets are known. Unless previous work missed thousands of HAP1 targets, the vast majority of the 3640 trans eQTLs at HAP1 must reflect indirect, secondary consequences of the direct transcriptional effects. HAP1 is an activator of genes involved in cellular respiration. Thus, the many secondary effects of the BY HAP1 allele on gene expression may be mediated by cellular responses to altered metabolism arising from reduced respiration. Our Supplementary Files and Datasets provide detailed information about each hotspot. Source data 8 contains a table that gives an overview of the hotspots, including their location, genes affected (details in Source data 9), and analyses of function (details in Source data 10) and transcriptional regulation (details in Source data 11) of the target genes of each hotspot. Supplementary file 5 visually represents each hotspot region, and Supplementary file 6 displays gene networks formed by the strongest target genes of each hotspot. Causal genes underlying hotspots Functional analysis of eQTL hotspots requires identification of the underlying causal genes, which has been challenging to do systematically. We developed a multivariate fine-mapping algorithm that narrows hotspot positions by leveraging information across the genes that map to each hotspot (Materials and methods). Briefly, we used all genes with an eQTL on a given chromosome and regressed out genetic factors on all other chromosomes and additional non-genetic factors. We reduced the dimensionality of the residual expression levels by singular value decomposition to capture linear combinations of traits that account for most of the variance in residual expression. We scanned the given chromosome for genetic influences on the multivariate distribution of these linear combinations, while controlling FDR via permutations. Finally, we used bootstraps to compute confidence intervals for hotspot locations (Figure 4 and 5). Genes located in hotspot regions. (A) Histogram showing the number of genes located in the hotspot regions. (B) A hotspot on chromosome VIII maps to the gene STB5. From top to bottom: the general region on the chromosome, the empirical frequency distribution of hotspot peak locations from 1000 bootstrap samples (Materials and methods), locations of BY/RM sequence variants (red: variants with ‘high’ impact such as premature stop codons (McLaren et al., 2016); orange: ‘moderate’ impact such as nonsynonymous variants; grey: ‘low’ impact such as synonymous or intergenic variants), and gene locations. The light blue area shows the 95% confidence interval of the hotspot location as determined from the bootstraps. The red line shows the position of the most frequent bootstrap marker. (C) Genes for which the BY allele at the STB5 hotspot is linked to lower expression are enriched for STB5 transcription factor (TF) binding sites in their promoter regions. The figure shows enrichment results for all annotated TFs (grey dots), with the strength of enrichment (odds ratio) on the x-axis vs. significance of the enrichment on the y-axis. The STB5 result is highlighted in red. With this approach, we resolved the locations of 26 hotspots to regions containing three or fewer genes (a total of 58 genes; Figure 4A). Three hotspots contained exactly one gene (GIS1, STB5, and MOT3). We previously identified and experimentally confirmed the causal genes at several major hotspots (MKT1 (Zhu et al., 2008), HAP1 (Brem et al., 2002), IRA2 (Smith and Kruglyak, 2008), GPA1 (Yvert et al., 2003), and the mating-type locus [Brem et al., 2002]). These were all correctly localized by the algorithm, validating this fine-mapping strategy. The 58 genes at 26 high-resolution hotspots are highly enriched for the causal genes underlying the hotspots, making it possible to systematically study the functions of hotspot regulators. These genes were less likely to be essential or to have a human homolog than other yeast genes but did not differ from other genes in their expression level or the number of physical or genetic interaction partners (Supplementary file 7). The hotspot genes had highly significant enrichments for gene ontology (GO) terms related to transcriptional regulation (e.g. GO:0006357 ‘regulation of transcription from RNA polymerase II promoter’: 19 genes among the 58; 4 expected; p=4e-9; Figure 4—figure supplement 1; Source data 12), as well as weaker enrichments for terms related to response to nutrient levels (GO:0031669; ‘cellular response to nutrient levels’: 8 genes, 1 expected, p=6e-6) These analyses indicate that causal hotspot genes are disproportionately involved in transcriptional regulation, a signal that was not picked up in an earlier study with fewer, less-well-resolved hotspots (Yvert et al., 2003). For example, we fine-mapped a new hotspot that affected 382 genes to a single gene, the transcription factor STB5 (Figure 4B). STB5 is a transcriptional activator of multidrug resistance genes (Kasten and Stillman, 1997). A previous analysis suggested reduced activity of the STB5 BY allele compared to the RM allele (Lee and Bussemaker, 2010). Consistent with this observation, we found that the promoters of genes whose expression was lower in the presence of the STB5 BY allele were strongly enriched for STB5 binding sites (Figure 4C). To further examine the role of sequence variation in transcription factor genes, we focused on transcription factors with variants predicted to be damaging to protein function such as premature stop codons or frameshifts. There are eight such genes in our data. Remarkably, six of these (GAT1, HMS1, PUT3, RFX1, SRD1, TBS1) were located in a hotspot, often very close to the estimated peak location (Figure 4—figure supplement 2). None of these expression hotspots have been reported previously, although variation at GAT1 has been reported to influence traits relevant for wine production (Salinas et al., 2012), and a premature stop codon in the RM allele of RFX1 has been linked to reduced activity of this transcriptional repressor (Lee and Bussemaker, 2010). The remaining two transcription factors with predicted damaging mutations did not overlap a hotspot. Of these, a predicted frameshift in YRM1 is very close to the end of the coding region, while a predicted frameshift in STB4 appears to be an annotation artifact: it resides in a region that is annotated as coding but that does not in fact appear to be transcribed (Figure 4—figure supplement 3, [Albert et al., 2014a]). Hotspot genes can also influence mRNA levels more indirectly – for instance, by shaping the cellular response to external stimuli such as nutrient availability. For example, we fine-mapped a hotspot, which influenced 645 genes, to an interval on chromosome VIII containing six genes (Figure 4—figure supplement 4A). One of these is ERC1, which encodes a transmembrane transporter. BY but not RM carries a frameshift in this gene, which removes the last two out of 12 predicted transmembrane helices of the protein (Fehrmann et al., 2013). This variant is known to reduce cell-to-cell variability (or
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7033, 281, 247, 11059, 323, 271, 43431, 2813, 11616, 247, 2613, 275, 253, 830, 273, 247, 5818, 13947, 247, 4275, 5909, 13, 347, 973, 347, 271, 5170, 2553, 285, 247, 2406 ]	Ebersberg, Germany) with the following sequence: MAP-LC3b: 5′- CGT CCT GGA CAA GAC CA-3′ (forward), 5′-CCA TTC ACC AGG AGG AA-3′ (reverse); SQSTM1/p62: 5′-AGG GAA CAC AGC AAG CT-3′ (forward), 5′-GCC AAA GTG TCC ATG TTT CA-3′ (reverse); GAPDH: 5′-CCA GAA CAT CAT CCC TGC AT-3′ (forward), 5′-CAG TGA GCT TCC CGT TCA-3′ (reverse). The evaluated efficiency of each set of primers was close to 100% for both target and reference genes. Real-time PCR was performed using the CFX 96 Real-Time System (Bio-Rad, Hercules, CA, USA) in a 10 µl total volume, using the iTaq SYBR Green Supermix (Bio-Rad), and with 500 n[m]{.smallcaps} primers. PCR cycling conditions were as follows: 94°C for 10 min, 40 cycles at 94°C for 15 s and 60°C for 1 min. Melting curve analysis was performed at the end of each PCR assay as a control for specificity. Data were expressed as C~t~ values and used for the relative quantification of targets with the ΔΔC~t~ calculation. To exclude potential bias due to averaging data transformed through the equation $2^{- \Delta\Delta C_{t}}$ to give N-fold changes in gene expression, all statistics were performed with ΔC~t~ values. Each experiment was carried out with four independent samples. Western blot (WB) analysis and FRA {#s4d} ---------------------------------- NSC34 cells were plated in 12-well multiwell plates at 80 000 cell/ml, transfected as previously described. For dose-dependent analysis, the cells were treated with 10 n[m]{.smallcaps}/100 n[m]{.smallcaps}/1 µ[m]{.smallcaps} Bicalutamide or 10 m[m]{.smallcaps}/100 m[m]{.smallcaps}/1 M trehalose. In the other experiments, the cells were treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. In experiments involving autophagy blockage, 10 m[m]{.smallcaps} 3-MA was added to the cells for the last 48 h. In experiments where proteasome was inhibited, the cells were treated with 10 µ[m]{.smallcaps} MG132 for the last 16 h (overnight treatment). After 48 h, cells were harvested and centrifuged 5 min at 100 g at 4°C; the cell pellets were re-suspended in PBS (added of the protease inhibitors cocktail, Sigma-Aldrich) and homogenized using slight sonication as previously described ([@DDU419C63]). Total proteins were determined with the bicinchoninic acid method (BCA assay, Euroclone). PC12/AR.Q112 cells were plated in six-well multiwell plates at 80 000 cell/ml, induced with 1 μg/ml of doxycycline and treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. After 48 h, cells were harvested and centrifuged 5 min at 100 g at 4°C; the cell pellets were re-suspended in RIPA buffer (added of the protease inhibitors cocktail, Sigma-Aldrich) and homogenized using slight sonication. The samples were centrifuged 15 min at 15 000 g at 4°C. The soluble fraction (supernatant) was separated from the insoluble one and the protein concentration was determined by the BCA assay. The pellet fraction was re-suspended in 20 μl of 4x sample buffer, and a relative amount was loaded into the gel, according to the protein assay on the soluble fraction. WB was performed on 15% SDS--polyacrylamide gel electrophoresis loading 10--15 µg of total proteins. Samples were then electrotransferred to PVDF (polyscreen transfer membrane, PerkinElmer, Waltham, MA, USA) using a semi-dry transfer apparatus (Trans-Blot^®^ Turbo™ Transfer System, Bio-Rad). The membranes were treated with a blocking solution containing 5% nonfat dried milk powder (EuroClone, MI, Italy) in Tris buffered saline with Tween for 1 h and then incubated with the following primary antibodies: (a) rabbit polyclonal AR-H280 (dilution 1 : 3000) to detect wt AR and ARpolyQ; (b) rabbit polyclonal anti-LC3 (dilution 1:4000) to detect LC3; (c) rabbit polyclonal anti-SQSTM1/p62 (dilution 1:4000) to detect SQSTM1/p62; (d) mouse monoclonal anti-α-tubulin (Sigma-Aldrich, dilution 1:4000) to detect total α-tubulin. Immunoreactivity was detected using the following secondary peroxidase-conjugated antibodies: goat anti-rabbit (Santa Cruz, dilution 1:20 000) was used to identify the anti-AR, the anti-LC3 and the anti-SQSTM1/p62 antibodies; goat anti-mouse (sc-2005, Santa Cruz, dilution 1:20 000) was used to identify the anti-α-tubulin antibody. The immunoreactive regions were then visualized using the enhanced chemiluminescence detection kit reagents (ECL prime Western Blotting Substrate, GE Healthcare, Maidstone, UK). The same membranes were subsequently processed with different antibodies to detect the levels of different proteins in the same sample loaded on the gel, after stripping for 10 min at room temperature (StripABlot, EuroClone). FRA was performed by sample filtration through a 0.2 µm cellulose acetate membrane (Whatman, GE Healthcare) using a Bio-Dot SF Microfiltration Apparatus (Bio-Rad) and loading 9 µg (NSC34 cells) of the total proteins or 1.5 µg (PC12) of the supernatant fraction. Slot-blots were probed as described for WB to detect AR.Q46 or AR.Q112. A ChemiDoc XRS System (Bio-Rad) was used for the image acquisition of WB and FRA. Optical intensity of samples assayed with WB or FRA was detected and analyzed using the Image Lab software (Bio-Rad). Fluorescence, IF and microscopy on NSC34 cells {#s4e} ---------------------------------------------- NSC34 cells were plated in 12-well multiwell plates containing coverslips at 70 000 cells/well density, transiently transfected with the plasmid coding for GFP-ARQ48 as previously described and treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. The cells were then fixed and processed as previously described (Sau, 2007). To analyze LC3 and SQSTM1/p62 protein expressions, we used the following primary antibodies: rabbit polyclonal anti-LC3-B antibody 1 : 1000 (Sigma-Aldrich) in 5% nonfat milk, rabbit polyclonal anti-SQSTM1/p62 antibody 1 : 1000 (Abcam, Cambridge, UK) in 5% nonfat milk. Secondary antibodies used were: Alexa 488 anti-rabbit and Alexa 594 anti-rabbit (Life Technologies) 1 : 1000 in milk. Cells were stained with DAPI to visualize the nuclei. An Axiovert 200 microscope (Zeiss Instr., Oberkochen, Germany) equipped with FITC/TRITC/DAPI and combined with a Photometric Cool-Snap CCD camera (Ropper Scientific, Trenton, NJ, USA) was used. Images were processed using the Metamorph software (Universal Imaging, Downingtown, PA, USA). Statistical analysis {#s4f} -------------------- Statistical analysis has been performed using one-tailed Student\'s t-test for two group comparisons and one- or two-way ANOVA for three or more group comparisons using the PRISM software (GraphPad Software, La Jolla, CA, USA). Conflict of Interest statement. None declared. FUNDING {#s5} ======= This work was supported by Telethon---Italy (GGP07063 and GGP14039) to A.P.; AriSLA Foundation Italy (ALS_HSPB8) to A.P.; Italian Ministry of Labour, Health and Social Affairs (Convenzione Fondazione Mondino/UNIMI) to A.P. and (Giovani Ricercatori) to V.C.; Regione Lombardia to A.P.; Universita' degli Studi di Milano to A.P. and P.R.; Fondazione CARIPLO (2008-2307) to A.P.; Fondation Thierry Latran, France (FTL n. AAP091102) to A.P., Association Française contre les Myopathies (project n. 16406) to A.P. Funding to pay the Open Access publication charges for this article was provided by Fondazione Telethon, Italy. [^1]: E.G. and P.R. equally contributed to this study. WO 2013/139685 A1 relates to a valve for an inhalation device comprising a base in the form of a ring defining a central opening, as well as an upper surface and a lower
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13, 285, 627, 310, 642, 2714, 6055, 2530, 323, 7996, 2144, 13, 3569, 2144, 13, 5268, 14, 1595, 4801, 15863, 13, 5454, 20196, 13, 3739, 1491, 13, 390, 4753, 5010, 30082, 762, 253, 1569, 1806, 3096, 47052, 5405, 12734, 21960, 5037, 1368, 489, 4879, 275, 617, 6206, 15, 187, 187, 688, 4162, 4240, 13, 3196, 15, 5171, 7416, 530, 15, 52, 15, 18718, 15657, 18059, 3354, 313, 37, 14, 1372, 10, 275, 16984, 253, 48483, 272, 5128, 387, 253, 26580, 3162, 313, 52, 15, 854, 1508, 10, 281, 3523, 436, 8411, 273, 7108, 457, 16650, 10737, 3570, 285, 3657, 2208, 6338, 432, 10568, 7108, 281, 17611, 7996, 1491, 327, 616, 5865, 4852, 275, 1340, 281, 3553, 390, 294, 14, 9553, 253, 2586, 15, 187, 187, 16881, 6659, 876, 795, 27696, 15362, 3, 34, 18468, 588, 513, 2761, 2712, 281, 1978, 616, 2628, 13, 1014, 2489, 247, 43371, 3, 428, 36909, 296, 6104, 834, 6473, 34879, 45895, 6514, 13882, 249, 263, 2859, 14576, 285, 12990, 80, 25088, 316, 1563, 11935, 11037, 28857, 323, 29931, 15, 187, 34, 1884, 14, 2913, 14, 744, 5343, 3559, 342, 24934, 13, 25601, 13882, 249, 263, 2859, 14576, 13, 11134, 987, 17754, 14855, 13, 374, 2607, 1563, 11935, 11037, 28857, 323, 29931, 15, 7403, 4950, 7101, 8376, 2254, 13267, 12990, 80, 25088, 316, 342, 35369, 2329, 1341, 275, 253, 12990, 255, 1025, 2406, 629, 273, 11935, 5961, 15, 380, 277, 1546, 285, 45861, 12834, 33172, 8379, 342, 3426, 6064, 273, 253, 12990, 80, 25088, 316, 15, 15413, 9108, 1720, 11682, 187, 187, 15413, 9108, 1720, 11682, 369, 247, 4022, 17478, 1984, 8027, 407, 5417, 56, 24837, 670, 697, 1386, 273, 17478, 5098, 1754, 327, 3607, 273, 253, 20953, 2567, 14026, 9108, 15, 3932, 3978, 4022, 13, 436, 42440, 5975, 2400, 954, 273, 5417, 56, 434, 14026, 9108, 26465, 715, 253, 14026, 9108, 43878, 7225, 21368, 13, 970, 253, 990, 273, 15033, 347, 697, 25251, 7360, 13, 534, 840, 4821, 342, 3973, 41054, 15, 1198, 4596, 4765, 13, 5417, 56, 7945, 253, 42440, 15, 187, 187, 15633, 187, 510, 14026, 9108, 1720, 11682, 42440, 11029, 281, 29623, 5417, 56, 434, 1211, 9508, 273, 34717, 398, 285, 443, 15, 42, 15, 9915, 715, 247, 6096, 10325, 273, 5810, 432, 2710, 14026, 9108, 17739, 13, 534, 574, 3053, 342, 14698, 35992, 1342, 285, 444, 15, 500, 15, 4137, 434, 380, 34717, 398, 27, 496, 5073, 14046, 275, 4437, 655, 13, 5826, 15, 9916, 285, 10929, 1406, 1920, 84, 43482, 1096, 327, 4022, 846, 14026, 9108, 47414, 616, 17478, 1984, 3570, 432, 24466, 35018, 15, 12121, 3083, 285, 353, 15, 34, 15, 52, 15, 44, 15, 497, 253, 1390, 30733, 323, 253, 2362, 2962, 15033, 15, 17842, 4240, 285, 4765, 13, 253, 5810, 273, 29770, 3927, 41362, 327, 253, 31433, 273, 253, 2362, 2962, 3973, 41054, 15, 380, 1720, 11682, 42440, 7945, 342, 253, 34717, 398, 27, 914, 280, 1406, 1054, 9141, 447, 15, 187, 187, 53, 262, 868, 187, 187, 48, 1251, 80, 272, 2962, 187, 187, 4041, 14, 28853, 187, 187, 5035, 671, 2490, 5552, 273, 26465, 1754, 327, 14026, 9108, 3607, 187, 187, 4941, 2490, 187, 1413, 27, 1838, 56, 24837, 187, 1413, 27, 2115, 280, 1984, 29393, 84, 187, 1413, 27, 15413, 9108, 187, 1413, 27, 6961, 26465, 11386, 84, 187, 1413, 27, 7798, 26465, 47834, 187, 1413, 27, 9019, 3083, 187, 1413, 27, 40, 15, 42, 15, 9915, 26465, 187, 1413, 27, 30998, 253, 11122, 3696, 429, 187, 1413, 27, 34191, 14459, 26465, 187, 1413, 27, 22904, 398, 26465, 43743, 187, 187, 25074, 14, 11375, 14768, 17337, 253, 987, 281, 5206, 5520, 12922, 285, 4980, 17340, 8333, 326, 476, 3157, 616, 43689, 84, 285, 5649, 616, 5870, 15, 18567, 14, 40, 6329, 42123, 556, 48283, 253, 16253, 273, 24663, 28136, 19492, 275, 1142, 4343, 13, 15979, 281, 253, 14549, 2368, 273, 20372, 49525, 897, 13, 23635, 13, 285, 14192, 15, 510, 16061, 33341, 3905, 375, 28299, 399, 17608, 187, 187, 688, 4267, 13, 2136, 32316, 275, 16861, 3982, 776, 767, 5870, 2366, 323, 752, 651, 5276, 281, 320, 247, 1077, 7574, 2338, 528, 4804, 15, 2732, 1142, 1107, 273, 2057, 2444, 323, 4471, 14, 25736, 18674, 390, 3515, 776, 1211, 4413, 13, 359, 313, 34706, 466, 13, 19436, 13, 22739, 285, 12429, 10, 6888, 326, 359, 574, 19767, 10861, 5239, 285, 497, 4704, 323, 247, 747, 15865, 428, 38857, 247, 4260, 14, 8206, 8891, 342, 247, 4096, 2581, 685, 247, 367, 47030, 15, 187, 187, 688, 4059, 359, 4395, 281, 7511, 606, 2604, 357, 606, 275, 253, 2798, 273, 3905, 375, 285, 3517, 8156, 326, 275, 436, 2659, 2120, 273, 14664, 12584, 13, 247, 22759, 4491, 369, 1327, 14, 46408, 15, 20389, 1417, 281, 1333, 13, 436, 1160, 4560, 1175, 3290, 12173, 1077, 2834, 15, 1244, 359, 2389, 776, 12173, 2, 2732, 690, 3574, 70, 18628, 15513, 285, 1199, 2561, 13, 359, 2210, 281, 253, 6452, 326, 359, 476, 513, 352, 9361, 285, 253, 1980, 3114, 812, 5649, 275, 253, 1232, 15, 187, 187, 1992, 1071, 253, 2934, 13, 247, 4737, 273, 4473, 369, 9009, 13, 534, 310, 816, 247, 18612, 1039, 273, 3981, 346, 1466, 434, 512, 3698, 15167, 10556, 327, 2301, 4351, 13, 755, 2186, 273, 247, 14664, 12584, 285, 923, 752, 359, 476, 513, 3446, 844, 33437, 495, 14664, 12584, 432, 2305, 15, 37646, 275, 596, 249, 6018, 80, 20186, 13, 670, 1884, 14, 32117, 3345, 273, 7511, 606, 2604, 357, 606, 3874, 313, 7710, 15, 37646, 285, 2021, 35957, 1840, 481, 3900, 12445, 275, 253, 2170, 574, 2455, 2326, 247, 14664, 12584, 8463, 264, 1078, 13, 2305, 15, 37646, 3534, 441, 253, 4839, 281, 11572, 253, 5199, 15, 844, 8463, 264, 253, 1264, 14664, 12584, 1046, 1388, 323, 721, 3618, 13, 37504, 342, 3240, 271, 8446, 15, 844, 840, 3982, 253, 8463, 896, 281, 3874, 285, 13, 347, 604, 407, 10721, 313, 395, 846, 247, 1643, 3302, 12330, 32074, 1157, 776, 41100, 13, 22739, 3531, 352, 715, 253, 806, 14604, 273, 7777, 17319, 12173, 15, 187, 187, 1231, 840, 1160, 776, 1211, 5497, 4396, 609, 14797, 13, 15438, 31797, 13, 39191, 13, 6749, 10777, 285, 36187, 886, 640, 13, 285, 6096, 776, 2332, 1885, 1386, 342, 1980, 2739, 28265, 13, 25633, 10111, 13, 15114, 285, 3858, 15, 844, 497, 760, 2546, 581, 1953, 27, 773, 3039, 588, 368, 1265, 7721, 187, 187, 6067, 806, 807, 369, 2120, 273, 7587, 285, 9546, 3339, 2820, 281, 755, 253, 2136, 598, 285, 3515, 15, 733, 3053, 342, 9433, 13, 285, 1146, 7012, 323, 13, 898, 1027, 2208, 23937, 13, 534, 369, 642, 3477, 8151, 15, 844, 2918, 12888, 323, 4750, 6887, 285, 14565, 2030, 9957, 42934, 23729, 665, 497, 5480, 281, 789, 342, 253, 10412, 20055, 606, 313, 66, 11453, 1307, 323, 34550, 481, 187, 187, 6067, 43248, 24773, 13, 3196, 15, 27516, 13, 369, 10166, 275, 33074, 347, 247, 26925, 342, 818, 1107, 273, 2793, 275, 253, 22759, 2136, 285, 16544, 3905, 80, 13, 4383, 13, 9883, 708, 5112, 15, 754, 556, 644, 9073, 441, 432, 253, 5068, 13, 342, 1463, 14664, 12584, 1557, 13, 19355, 1491, 12154, 342, 14768, 275, 689, 1722, 1027, 18430, 13, 670, 2301, 4351, 13, 7062, 8779, 285, 2087, 1557, 273, 14664, 12584, 5043, 3733, 313, 395, 247, 1643, 25945, 9506, 10, 327, 3975, 11232, 496, 49641, 318, 15, 187, 187, 4553, 2607, 273, 3652, 285, 31761, 1458, 46173, 4420, 273, 18593, 1321, 10583, 275, 9008, 13, 327, 253, 1283, 394, 273, 4163, 4022, 776, 806, 14664, 12584, 7244, 13, 285, 253, 3905, 375, 28299, 399, 17608, 3395, 253, 806, 273, 697, 2238, 275, 253, 2586, 15, 4538, 459, 9423, 483, 187, 187, 27129, 1491, 310, 14049, 342, 27243, 4302, 15, 187, 187, 14344, 42855, 187, 187, 14344, 4156, 15076, 1621, 5927, 1340, 15, 187, 187, 11185, 187, 187, 36599, 849, 281, 4647, 465, 1100, 10537, 12342, 285, 1555, 12909, 342, 4878, 2052, 2610, 457, 84, 611, 1100, 10537, 27, 380, 322, 30554, 4155, 285, 4878, 2148, 12917, 13, 495, 5784, 17897, 2, 2726, 625, 685, 337, 13, 1518, 2120, 14, 4897, 33954, 13, 436, 4122, 5304, 2505, 6131, 247, 24863, 314, 12800, 1007, 387, 253, 20847, 985, 285, 849, 13370, 1159, 347, 5497, 735, 13, 33226, 13, 285, 10308, 14460, 275, 253, 2133, 15, 3512, 2596, 10949, 253, 6662, 932, 273, 2605, 285, 3200, 13, 1690, 5667, 28939, 326, 310, 908, 275, 465, 1100, 10537, 15, 3512, 5761, 10949, 253, 20847, 985, 1690, 253, 24071, 273, 20847, 285, 10942, 451, 7944, 15, 3512, 9064, 4428, 247, 7000, 1263, 273, 253, 22136, 273, 253, 2133, 15, 1244, 1390, 314, 13, 3512, 7874, 33888, 849, 13370, 1159, 15, 831, 747, 11166, 671, 38716, 271, 512, 14, 1826, 8857, 327, 1794, 485, 2291, 982, 13, 625, 685, 2233, 3909, 3492, 29205, 13, 285, 271, 18366, 6616, 2086, 15, 1310, 368, 971, 247, 11080, 4685, 273, 6616, 1159, 285, 849, 281, 4647, 326, 3640, 327, 253, 2628, 13, 840, 627, 457, 84, 642, 1805, 7102, 685, 4878, 2052, 2610, 2, 187, 187, 4814, 29621, 187, 187, 31996, 486, 273, 31845, 18418 ]	line shown above. Pay attention to the first ID hex code part '''"18d1"'''. That id is used in the following steps to identify this device. Create a new file (as root) <code> sudo gedit /etc/udev/rules.d/51-android.rules </code> with the following content <code> SUBSYSTEM=="usb", SYSFS{idVendor}=="18d1", MODE="0666" </code> Make sure that the text after {idVendor} is the same as the device id found when using the lsusb command. Save and exit the editor.Currently, Department of Homeland Security (DHS) policies permit customs and border authorities to seize and search American citizens’ smartphones and other digital devices when they travel internationally to and from the United States, without a warrant or suspicion of wrongdoing. The FSO subcommittee will hear testimony regarding the history of this so-called “border search exception” to the warrant requirement of the Fourth Amendment and will evaluate the far-reaching privacy implications of DHS’ policy of allowing customs and border officials to seize and search the digital devices of international travelers without a warrant. In April 2017, Dr. Paul joined U.S. Senator Ron Wyden (D-OR) in introducing the Protecting Data at the Border Act (S. 823) to stop this violation of Americans’ Fourth Amendment rights and prevent government officials from requiring Americans to disclose sensitive information on their digital lives in order to leave or re-enter the country. “I think that most Americans could agree that it’s reasonable to let customs officials search suitcases for contraband. What’s unreasonable is that the government lawyers want you to believe that there’s no difference between a suitcase and a smartphone. I disagree, and here again, I think most Americans would, too,” Dr. Paul said in his opening statement. Currently, Department of Homeland Security (DHS) policies permit customs and border authorities to seize and search American citizens’ smartphones and other digital devices when they travel internationally to and from the United States, without a warrant or suspicion of wrongdoing. The FSO subcommittee heard testimony regarding the history of this so-called “border search exception” to the warrant requirement of the Fourth Amendment and evaluated the far-reaching privacy implications of DHS’ policy of allowing customs and border officials to seize and search the digital devices of international travelers without a warrant. “There are no statutory limits on who can see this information, how long it can be kept, or how it can be used, and there is no special protection provided for sensitive material, political material, client-attorney privilege, trade secrets, medical information, or materials otherwise privileged under the law,” Georgetown Law Professor Laura Donohue noted in her testimony. In April 2017, Dr. Paul joined U.S. Senator Ron Wyden (D-OR) in introducing the Protecting Data at the Border Act (S. 823) to stop this violation of Americans’ Fourth Amendment rights and prevent government officials from requiring Americans to disclose sensitive information on their digital lives in order to leave or re-enter the country. __________________________________________________ ________________"A politician will do almost anything to keep their job, even become a patriot" - HearstSpontaneous cerebrospinal fluid rhinorrhoea and pneumocephalus following temporal lobectomy for epilepsy. A 30-year-old female presented with headache, CSF rhinorrhoea, mild right facial weakness, 2 months following temporal lobectomy for epilepsy. CT revealed marked intraventricular pneumocephalus with breached air cells in the pneumatized lower part of temporal bone. The dural and bony defects repaired successfully with complete resolution of the pneumocephalus.Hasbro Reconstruction Hasbro Reconstruction was a 2016 comic book launch by IDW Publishing about its line of comic books based on properties of the toy company Hasbro. Since June 2016, this branding converged most of IDW's Hasbro comics into the Hasbro Comic Book Universe, using the end of Revolution as its launching pod, which then continued with First Strike. For November 2018, IDW concluded the branding. Background The Hasbro Reconstruction branding serves to converge IDW's own versions of Transformers and G.I. Joe into a shared universe of characters from various Hasbro brands, which had started with Simon Furman and E. J. Su's The Transformers: Infiltration in October 19, 2005. Rom and Micronauts reappeared on 2016 after Hasbro regained their comic book rights from Marvel Comics. Action Man and M.A.S.K. were the last additions for the event series Revolution. Between 2017 and 2018, the characters of Visionaries debuted on the aftermath of the event series First Strike. The Reconstruction branding concluded with the Transformers: Unicron miniseries. Titles Ongoing series One-shots See also List of comics based on Hasbro properties References Category:IDW Publishing Category:Comic book reboots Category:Hasbro Category:2016 comics debuts Category:2018 comics endings Category:Action Man Category:G.I. Joe comics Category:Rom the Spaceknight Category:Science fiction comics Category:Transformers comicsJustice Small-holder farmers deserve the right to choose improved seeds and modern agricultural practices that can improve their livelihoods and benefit their families. Anti-GMO activism has stalled the adoption of genetically engineered crops in many countries, contributing to the perpetuation of unsafe pesticide use, hunger, and poverty.The Story Behind Laos Buffalo Dairy In 2010, business commitments in Singapore brought our two families together for what would prove to be a very fortuitous meeting. After many years of either working for multi-national corporations or running our own companies, we (Susie, Steven, Rachel and Matt) discovered that we had complementary skill sets and were ready for a new adventure - aka a mid-life crisis with a purpose rather than a Porsche. In 2014 we moved to Luang Prabang in the heart of Laos and soon realized that in this land full of buffalo, a dairy industry was non-existent. Needless to say, this made finding good quality cheese very difficult. And we love our cheese! After some sleepless nights and much research, we came to the conclusion that we can do it ourselves and the local community could benefit in the process. To test the idea, a proof of concept was implemented, which is just a fancy way of saying "Let's all watch YouTube videos on milking, get hold of a buffalo and see what we can do". We rented 3 buffalo from Mr. Eh in Thin Keo Village, about 30-minutes outside of Luang Prabang town (Mr. Eh and family pictured above). While nobody in the area had ever seen a buffalo milked before, Mr. Eh gave us the chance to pilot the procedure. We milked the three buffalo every day for 6 weeks, invariably with quite an audience. We then brought the milk back to town and, as if by magic (and after a few initial tears :-) , our Chef, Rachel turned it into the first batch of truly delicious cheese. We then made our own mozzarella, ricotta, yogurt, ice cream and cheesecake, and shared our trial product line with local food suppliers, grocery stores, restaurants and friends. We were only asked one question: “When will you start?” Our first year was full of trials and tribulations trying to get the business up and running. It started with applying, and being approved for, 9 different government licenses, which was no easy feat. We held interviews for staff positions and hired 25 adventurous souls who were prepared to work with the crazy Falang (a friendly term for foreigners). Our veterinary consultant, Dr. Som, was trained in Cuban as a vet with 7 years of experience in the dairy business and speaks Lao, English, Spanish & French. He has been helping us from the beginning, with proper buffalo care, hosting information sessions with farmers in over 17 different villages, about milking, vaccinating and general care of buffalo plus training (and a few entertaining moments) on Artificial Insemination. After months of building and planting 15 hectares of Napier grass in preparation, on the 18th of July 2016 our first buffalo arrived, and the Laos Buffalo Dairy became the first of its kind in the country.Secure Checkout Personal information is secured with SSL technology. Free Shipping Free global shipping No minimum order. Description Learn how to apply kinesiology concepts and treat dysfunction with Muscolino’s Kinesiology: The Skeletal System and Muscle Function, 3rd Edition! With more than 1,200 full-color illustrations, this highly visual text offers a vividly illustrated look at the skeletal system and how muscles function as movers, antagonists, and stabilizers in the body. Part One covers the fundamentals of structure and motion, including essential terminology that is used in kinesiology. Part Two covers the skeletal system including the makeup of skeletal and fascial tissues. Part Three contains a detailed study of the joints of the body. And lastly, Part Four examines how muscles function. This new edition also boasts an all-new chapter on biomechanics, more than 100 online video clips, and an interactive muscle program. If you want a thorough understanding of muscle function and how to apply that knowledge on the job, then there’s no better guide than Muscolino! Key Features Coverage of strengthening exercises
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187, 187, 52, 1322, 3077, 52, 187, 187, 64, 4553, 8986, 288, 487, 1808, 318, 13, 3802, 5351, 1705, 562, 275, 253, 7203, 39426, 1108, 285, 403, 25122, 5728, 407, 2872, 285, 1711, 15, 1583, 403, 10208, 760, 10329, 35599, 13, 281, 45726, 731, 13, 323, 247, 2129, 15, 2058, 11051, 376 ]	a kilo of_ skorpios _, scorpion fish, cleaned but left whole. It was a triumph. If you wish, you may substitute a combination of two red mullet, filleted; six large prawns; and 500 g (1 lb) of mixed mussels and clams – you can still follow the method below._ SERVES 4–6 Cook 3 potatoes, sliced, in a deep frying pan with light olive oil and add a very finely chopped onion; then add a glass of white wine and boil furiously, so that the alcohol evaporates. Add the pulp, minus seeds and skins, of 4 tomatoes, a teaspoon of hot paprika, a tablespoon of chopped parsley with the stalks, some black pepper and, if you wish, a teaspoon of tomato paste. Cover this with a lid and add a little hot water from the kettle, then simmer until the potatoes are completely soft. In a blender, add a chopped garlic clove to a little olive oil and blend to make a thick, pungent paste. Add this when your sauce is amalgamated and the potatoes are completely soft. Then place the fish on top of this mixture and poach them while the sauce reduces, so that the fish is moist and perfectly cooked, and stands a little proud of the sauce. Serve in deep, warm bowls. CHAPTER 5 WILD THINGS THE DEATH OF PAN _According to the first-century historian Plutarch, one night a boat was sailing through the dark, close to the island of Paxos; most of the passengers were still awake. Suddenly they heard a strange voice, which seemed to be coming over the water from the island. It called, 'Thamus!' 'Thamus!' – which was the name of the captain of the vessel. He remained silent and afraid; but it called again and again. Finally he answered and the voice said, 'Go to the harbour near Butrinto, and announce... that the Great Pan is dead.'_ _Thamus did as he was told (Butrinto is on the Albanian side of the Corfu channel, just north of Paxos) and immediately there was wailing of astonishment and grief from all who heard him. The news travelled fast to Rome, where Tiberius Caesar himself called Thamus to come before him. Pan, the god of animals and all wild things; Pan, the hoof-footed piper at the gates of dawn... all felt shocked and somehow bereft at the death of a god._ _But a hundred years later, when the Roman writer and scholar Pausanias toured Greece, he found that Pan's shrines and sacred caves were still visited and revered. And sometimes, when walking alone over the cliffs in the early morning, the sounds of hidden birds and a rustling through the trees make one fleetingly conscious – like a flash across one's peripheral vision – of the presence of something..._ _HORTA_ _Rumps in the air, bent deeply at the waist, women – from widows to very young girls – are to be seen all over the island of Paxos in March and April, gathering the first luscious green shoots of spring. The Greeks have a passion for all these bitter-sweet weeds, known as_ horta _. Electra and her two friends, both called Nitza, know by sight those which are good for salads or for cooking._ _The ancients loved peppery, bitter leaves and they searched out the bulbs of grape hyacinths, which stud the hillside with miniature patches of blue._ _Today's islanders love them too, adding spinach, chard, lovage and sorrel._ _Famine is within living memory. During the German occupation of Athens in the last war, an estimated 300,000 starved to death; their bodies were collected off the street each morning. So great was the hunger that the hills were stripped bare of wild greens... war-time was tough on the island, too. Today, when you see strapping teenagers towering above their tiny grandparents, you reflect on the dramatic change in diet._ Horta _are still treasured. They are free, growing abundantly on hillsides, at the cost of a little stooping to pick them, with no expensive imports by boat._ Radíkia _encompasses wild chicories, dandelions and all kinds of bitter leaves. Greeks cook the leaves and shoots of mallow; they look out for wood sorrel and field sorrel. They seize upon comfrey leaves, wild fennel and wild beets,_ vlíta. _Serve your weeds steamed, tossed in some good olive oil, with lemon tears and lemon zest; wilted, with a little minced garlic, or some olives; buttered, especially if you have spinach and chard, with mint; or chopped, ready for stuffing in pasta, in which case a generous grind of nutmeg would be splendid._ _Add chopped drained_ horta _to little pastry tarts, topped with olives, capers anchovies, béchamel or hollandaise... purists select the finest little leaves for a salad, with a few slices of radish or raw carrot, and droplets of cold-pressed extra-virgin olive oil._ WILD GREEN SOUP _This can be made from a basketful of leafy vegetables; or, very pleasingly, from the three witches that curse our gardens: nettles, dandelions and ground elder. Pick only the dainty young leaves of the nettles, young ground elder leaves and small dandelion leaves._ SERVES 4 150 g (5 oz) young nettle tops, dandelion leaves and ground elder; mixed with spinach or chard (optional) 2 tablespoons basmati rice 1 litre (1¾ pints/4 cups) vegetable or chicken stock 1 onion, peeled and finely chopped 2 leeks, trimmed, washed and finely sliced 2 stalks celery, chopped 50 g (2 oz) butter Greek yoghurt to serve fresh mint leaves to garnish sea salt and black pepper Wash the greens thoroughly, using rubber gloves when touching the nettles, and discard any tough stalks. Wash the rice to remove the starch and add to a pan with the chicken stock, then simmer until the grains of rice are soft. Sweat the onion, leek and celery in butter in a large frying pan; cover and allow to cook gently for 10 minutes, stirring occasionally, until soft, but do not allow it to brown. Add the rice and stock to the pan, bring it to a simmer and cook for a further 10 minutes. Then add the wild greens, stirring them as they wilt; simmer them until the rice and nettles are tender. Season with salt and plenty of pepper. Purée the soup in batches, re-heat – but do not allow it to boil. Serve in warm bowls with a swirl of yoghurt and a little chopped mint on top. Note: if kept too long, the bright green colour will be lost, so if you need to make this ahead, prepare till just before you add the greens, and cook them when you want to eat. FORAGING ON THE SHORE _In February, seemingly without fail, there are ten days of surprising warm weather. The sea is glassily calm; the balmy air suggests, deceptively, that spring has arrived. These are the_ alkionides meres _, the halcyon days – thanks to Alcyone, for whom Zeus had a passion. When his wife Hera found out, she changed Alcyone into a bird – and Zeus compassionately gave Alcyone ten days of calm weather, in which to lay her eggs... The Paxiots take advantage of this by going down to the seashore to gather limpets, snails and seaweeds._ _One seaweed is named_ oneira _– which means dream; these beautiful green and white weeds float just under the water. They use them for a salad with limpets, and some rice._ _The tiniest limpets are_ patales _– a great delicacy. They are pure gellified obstinacy to remove, so use the sharp tip of one shell as a lever to prise out the limpet, and swallow it raw, to taste the sea. There are cone-shaped limpets, too; their raw flesh is blended and eaten on top of fried rice._ SAMPHIRE _We in Britain are lucky enough to have samphire, as the Greeks do; why do so few appreciate it? It is my favourite wild food. Take a piece of plainly grilled fish, dressed in a little oil, with lemon juice and rock salt in which a few dried fragments of oregano have been pounded. Serve it with a warm dish of_ krìtamo _: tiny green stems of samphire that have been blanched very briefly, then anointed with a little lemon juice, the very best olive oil, and dressed with some 'tears' of lemon segments... a dish with an incredible depth of flavour._ _When preserved in white wine vinegar, samphire can be used in winter salads._ SNAILS _After winter hibernation, snails come out in the spring showers – and are promptly collected by young and old. They are fed only garden greens, to purge them, for a week. At Electra
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281, 346, 1342, 7468, 16, 22477, 3, 327, 253, 1669, 1133, 1930, 15, 187, 187, 8195, 1039, 281, 3186, 323, 4222, 2401, 390, 7714, 4753, 310, 281, 897, 3186, 2426, 275, 253, 15650, 29041, 273, 5002, 285, 2701, 253, 8848, 281, 22681, 2499, 327, 253, 987, 1133, 1930, 15, 1310, 368, 1089, 247, 4849, 368 ]	applied to newborn piglets, those receiving the highest score of 4 had lower blood pCO~2~, higher pH and lower lactate and glucose than those with the lowest liveborn score of 2 \[[@B11-animals-09-00885]\], indicating that they had suffered less birth asphyxia. In support of this, piglets with severe meconium staining (\>40% covering of the skin) recorded a lower viability score at birth \[[@B46-animals-09-00885]\]. Viability is important as locating the sow's udder and outcompeting littermates ensures access to colostrum/milk. Time taken for the piglet to reach the udder was reported to increase with increased pCO~2~ and blood lactate as well as with decreased pH \[[@B11-animals-09-00885]\]; meconium-stained piglets took twice as long to contact the sow's udder than unstained piglets \[[@B46-animals-09-00885]\]. Langendijk, et al. \[[@B12-animals-09-00885]\] showed that asphyxia impacted on the time it took a piglet to successfully feed and most importantly, the volume of colostrum ingested. Piglets with high lactate levels were slower to feed and took in less colostrum than those without evidence of asphyxia. The measurement of such behaviours is important given the link between colostrum intake and piglet survival \[[@B47-animals-09-00885]\]. Catecholamines are released to stimulate liver glycogenolysis after asphyxia \[[@B11-animals-09-00885]\]. Because of this, piglets that are asphyxiated \[[@B11-animals-09-00885],[@B32-animals-09-00885]\] and that die during the first ten days \[[@B48-animals-09-00885]\] display elevated blood glucose levels. So, taken collectively, asphyxiated piglets have lower vitality which will compromise feeding and mobilise glycogen stores at a rapid rate, making hypoglycaemia likely. Therefore, it is imperative to restore glucose levels in asphyxiated piglets immediately and employ colostrum management strategies such as those outlined by Alexopoulos, et al. \[[@B47-animals-09-00885]\]. Asphyxiated piglets also struggle with regards to temperature homeostasis. Heavily meconium-stained piglets recorded rectal temperatures 1.7 °C cooler at birth than those with little to no staining \[[@B46-animals-09-00885]\]. Rectal temperature at 24 h of age has also shown to increase with pH and with decreased pCO~2~ and lactate \[[@B11-animals-09-00885]\], and so the negative effect of birth trauma on temperature is maintained in the days following birth. However, Herpin, et al. \[[@B49-animals-09-00885]\] suggested that it is not homeothermy per se that is impaired in asphyxiated piglets, but rather the link between birth trauma, colostrum intake and carbohydrate metabolism (explored in the previous paragraph) that results in the low body temperature. Regardless, with reduced rectal temperature, these piglets are at increased risk of chilling. Thoresen, et al. \[[@B50-animals-09-00885]\] identified that secondary energy failure was reduced when piglets were cooled to 35 °C for 12 h after induced asphyxia, with this finding and others being responsible for the clinical application of therapeutic hypothermia for treatment of human neonatal hypoxic-ischemic encephalopathy. Thus, the commonly reported hypothermia in asphyxiated piglets may have neuroprotective effects. How to manage the rewarming event then becomes contentious. Wang, et al. \[[@B51-animals-09-00885]\] identified increased apoptosis when rewarming was rapid rather than slow (i.e., 2 h versus 8 h), and so a more gradual increase in body temperature of chilled piglets would result in the highest success rate. Given these impacts on a piglets ability to thermoregulate and ingest colostrum, perhaps it is not surprising that when no additional care is provided, mortality in the first week of life is doubled from 5.5% to almost 11% in asphyxiated piglets \[[@B12-animals-09-00885]\]. In addition to survival being reduced, piglet growth is compromised when birth trauma is experienced. When piglets are exposed to asphyxia, blood flow is reduced to the small and large intestines during the event, which resulted in intestinal lesions at 12 h of age \[[@B52-animals-09-00885]\]. Such damage to the gastro-intestinal tract would have ramifications for milk and colostrum absorption. Indeed, piglets with heavy meconium staining gained 168 g by day 5, compared with 520 g for control piglets \[[@B46-animals-09-00885]\]. By ten days of life, average daily gain (ADG) was shown to be inversely related to blood lactate levels at birth \[[@B11-animals-09-00885]\]. At weaning, ADG was reduced from 259 g/d to 245 g/d in least versus most asphyxiated piglets, respectively; from weaning to 10 weeks ADG was reduced from 721 g/d to 664 g/d in least versus most asphyxiated piglets, respectively \[[@B12-animals-09-00885]\]. From these studies, it is evident that asphyxiated piglets perform poorly with regards to growth not only in the farrowing house, but after the weaning event also. What is less clear is the mechanism behind the reduced growth rates. Is it simply that the less viable pigs ingested low colostrum levels (with colostrum intake influencing growth to six weeks of age \[[@B53-animals-09-00885]\]), or are there longer term impacts of asphyxia on the physiology and development of the pig? Ralph, et al. \[[@B54-animals-09-00885]\] demonstrated behavioural differences at the end of lactation (day 21) in piglets heavily stained with meconium suggestive of neurological shifts that persist outside the perinatal period. Further work examining whether there are long term gastro-intestinal changes in piglets experiencing asphyxia are warranted. 9. Conclusions {#sec9-animals-09-00885} ============== Using conservative estimates from this review, 10% of piglets are stillborn and 15% of those born alive are at an increased risk of significant morbidity and mortality from birth trauma. Assuming a total litter size of 15, this equates to 3--4 viable piglets per litter that will be affected by asphyxia, a figure that will only rise with increased prolificacy. The parturition process is almost exclusively responsible, with cumulative farrowing duration rather than birth interval explaining most of the damage to piglets. Interestingly, sows at risk of delivering asphyxiated piglets are already compromised before the expulsive phase. This means that interventions that are applied during the second phase when piglets are birthed will have little impact, and in some cases, may actually increase the odds of a dead or low-viability piglet. Asphyxiated piglets require special care immediately after birth as the condition impairs glucose and temperature homeostasis. Identifying ways to correctly manage the sow before parturition leading to a reduction in farrowing duration should be a priority in order to maximise piglet performance. P.L. and K.P. contributed equally to all aspects of this publication. This research received no external funding. The authors declare no conflict of interest. ![Distribution over different birthweight classes for stillborn piglets and liveborn piglets that survived to weaning (left panel) and neonatal mortalities and liveborn piglets that survived to weaning (right panel). The percentage on each Y-axis represents the percentage of piglets in each category (stillborn, neonatal mortalities, or liveborn piglets that survive to weaning) that fall into a particular birthweight class. In total, 1856 piglets were recorded (unpublished data). The data show that stillborn piglets and piglets that survive to weaning have a similar birthweight distribution, but that neonatal mortalities are skewed towards low birthweights.](animals-09-00885-g001){#animals-09-00885-f001} ![Effect of birth order on stillbirth (left panel) and measures of asphyxia (right panel) \[[@B12-animals-09-00885]\].](animals-09-00885-g002){#animals-09-00885-f002} You are here Find Special Collections materials Here is how you can do a basic search in SearchWorks to find all types of Special Collections materials: 1) Go to SearchWorks: http://searchworks.stanford.edu/ 2) Type in your search terms in the search box. Click on the word "search" 3) When the screen populates with your search results look at the left hand side and click on "location" 4) Select "Special Collections & Archives" as the location 5) The screen will populate with items found only in Special Collections and University Archives that match your search terms. From here you can refine your search even more by selecting format, author, publication year, etc. For example, if you wish to find archives of manuscript materials, you can limit format to "manuscript/archive" on the left hand side. Another way to search for archival or manuscript materials is to use search terms in the Online Archive of California and limit the institution to Stanford University on the right hand side. If you find a collection you
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13, 247, 629, 273, 479, 30685, 309, 574, 253 ]	canvas jacket. I have discovered something and I'm not sure what to do with it. It's possible there is a tie in with whatever it was Sandy was working on. But, as I said, I'm not sure how to proceed." "So why the questions?" "With Sandy, it was worry. I saw he was very worried when I spoke with him. And incredibly stressed. Probably drinking too much as a result. With you it's anger. It's very close to the surface and I'm not certain I should tell you any of what I have found." The urge to shake her hand off and walk away was immediate and powerful but she was right, the anger was too close to the surface. Frustration was keeping me wound up and in a state just below frenzy. I focused on those warm chocolate brown eyes and let the reassurance trickle in. Slowly my breathing relaxed and some of the tension eased out of my muscles. Her calm concern washed through me until I could take a breath without it catching. "Thanks." She gave my arm a gentle squeeze, a sad knowing smile on her face. "You tough guys are always a challenge." "Maybe not so tough." "No, definitely tough. I just wonder if you really realize just where that tough lives. But I digress. I do have things that need to be done. And one thing I feel should be done." "You've lost me there, Jill." She gave me a wry grin and walked over to the far corner of her office. She wheeled a cart with a TV and VCR on it so it faced the room. "Phillip, on Monday I was called in to treat a young woman. She hadn't gone to work and a coworker friend became concerned so she went to her apartment to check on her. The front door was unlocked and my patient was found huddled naked in the back corner of her closet. The friend called 911 when she couldn't get any response out of her. I understand things got pretty wild when a male paramedic tried to get her out of the closet." "Sounds like a response to a pretty brutal assault." "That's what the paramedics thought too. One was a woman and she managed to quiet the patient down to the point where she could be sedated. Once we got her on the wing I was able to give her an examination. She exhibited an unusual mix of symptoms. When no men were present she was almost catatonic in her responses but if she even glimpsed a man, she would become extremely agitated and display such violent behavior that we would have to physically restrain her." "Has she been able to communicate?" "Somewhat. Her mother lives in Winter Park and she came up to be with her daughter. With both the mother and I present I have been able to get her to talk but it has been very disjointed. Phil, we are talking about a very intelligent woman here. She was a paralegal in one of the more prominent law offices here in Jax. Very bright and personable." I nodded, wondering how it tied in with what I was working on. There was a strong mix of excitement and dread building inside me as my mind made a few minor quantum leaps. "Age?" "Twenty five." Attractive young professional woman, much like the two known victims. "You said you learned something. Something that needs to be dealt with." She nodded. "The physical examination I did showed she had been involved in fairly aggressive and rough sexual intercourse within 24 hours or so of admission. There is some bruising and scratching to indicate that. And the condition of her genitalia indicates that as well. Whoever she was with likes to play hard." "Abusively so?" Jill shrugged. "Not really. I've seen much worse." "Then why the strong reaction?" "At first I thought it could have been linked to her having a repressed nature prior to the incident. I interviewed her friend though and it appears she had been fairly normal in her sex life. If anything, she was aggressive. Dated quite a bit with no interest in settling down. I'm trying to contact some of her old boyfriends to see if I can get a better picture of what she was like but I don't think repressed is going to figure into it." It was becoming more obvious to me that Jill was more upset about this than I had previously noted. She was fidgeting with items on her desk as she spoke with me and the level of eye contact had dropped radically. "Jill? Have you reported this?" She looked at me and I was surprised at the haunted desperation in her face. "Reported what? There isn't enough evidence to prove assault. She wasn't beaten. And her friend said that other than being upset over another friend's disappearance about a month ago, she had seemed quite normal." Suddenly there were alarms going off in my head. It felt as if someone had grabbed my chest in a massive vise and cranked it for all they were worth. Jill saw the reaction and started. "What is it, Phil?" I waved her off impatiently. "So why did you call me?" "This morning I tried hypnosis. I had discussed it with her mother as a possible way of reaching past the block. I didn't think I would have much luck; you generally have to have some active participation with the patient to get them into a state where the suggestions work. I was wrong. As I said, she is a bright perceptive woman." She paused and met my eyes. "Her mother agreed to the idea just as she has agreed to letting you see the video tape I made of the session." "Has she seen it?" "God, no." I walked over and put my hands on her shoulders. She was trembling slightly, her eyes searching mine for some kind of reassurance. "Can you watch it again?" She shivered and closed her eyes. "I haven't stopped watching it. It keeps replaying in my head." I hugged her, pulling her close. I dreaded seeing whatever it was that had disturbed her so deeply but I knew I had to do it. "I can watch it alone." She shook her head. "No. I need to see it." She looked up at me. "Just hold my hand?" I let her go enough for her to reach the controls and get the thing started. Then she tucked herself under my arm as the screen came to life. I hadn't been prepared for the woman's appearance. Latino heritage was obvious in her dark hair, eyes and coloring but she was more than a little stunning. Even with the dulled vacuous expression and general disarray, there was a quality to her. Jill's voice was a soothing rhythm like flowing water, interrupted only slightly by the quiet monosyllabic responses from a slack mouth. It was eerie watching as the hypnosis took hold. The girl's name was Felice and at Jill's prompting, she seemed to come alive under deep hypnosis. Her mouth tightened into a smile that covered the slight overbite and dark limpid eyes took on a remembered sparkle. I could see why Jill didn't expect to find some quiet little mouse that had been afraid of sex in the woman's past. As the session took hold there was an aura, a vivacity that blossomed as Felice's natural persona came out of hiding. Jill's words guided her back to when her world had been safe and then began the journey into darkness. It was clear Felice had enjoyed her relationship with a man named Brian. Under different circumstances, her coquettish manner might have stirred the voyeur in me. It was almost like watching some kind of soft porn video as she spoke so seductively, bringing herself and her phantom lover to sensuous climax. Then suddenly, it changed. Terror flared in her eyes, her entire body went rigid as she fought to free herself from the grip of her lover. She began to scream in a hoarse guttural voice that made my throat ache in sympathy. Jill brought her back under control with some difficulty, almost forcing her back into the peace of forgetfulness. Jill reached a shaking hand over and pushed the stop button and then turned off the TV. "Did you catch what she said?" I nodded, the horror slowly settling in me. Felice's terror had struck a very primal chord in me. "Perro." "You know what it means?" "Spanish for dog." "Felice is first generation Cuban. Her parents escaped when Castro took over." I looked down at her, finally able to tear my eyes from the dark screen that still held the images of horror. It was burned into me beyond my retinas. Looking into Jill's eyes I could see it was the same for her. I hugged her, the embrace becoming fierce as we both tried to draw some comfort from the contact. "Jill, the tests you did. Did you find any physical evidence of her partner?" She nodded shortly against my chest, her arms clasping convulsively around me. "Some hair. And semen." I waited until the spasm passed with a confidence I already knew what her next words would be. "It wasn't human, Phil" She began to cry very quietly. I held her, a part of me wishing I had the
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1281, 258, 9, 89, 10, 426, 428, 89, 424, 20, 559 ]	is divided by a. 5 Let u be (-6)/((-5)/(220/8)). Suppose -6c + u = -63. Calculate the remainder when c is divided by 9. 7 Calculate the remainder when 27 is divided by (-2)/11 + (2 - (-72)/33). 3 Let h = 27 - -31. What is the remainder when h is divided by 12? 10 Suppose -4i - 14 + 4 = -5u, -6 = -3u + 5i. Suppose 0 = -4p + up + 36. What is the remainder when p is divided by 10? 8 Let m(j) = 19j - 43. What is the remainder when 119 is divided by m(3)? 7 What is the remainder when -3 - ((-1)/(-5) + 964/(-20)) is divided by 11? 1 Suppose -4 = 5y - 24. Suppose 4j - 2 = 3o + 12, -2o = -j + 6. Calculate the remainder when 23 is divided by (8 - y)/((-1)/o). 7 Let y = 174 - 305. Let x = y - -188. Calculate the remainder when x is divided by 20. 17 Let p(g) = g*2 + 4. Let m be p(0). Suppose 5k + mc = k + 68, 61 = 3k - 2c. What is the remainder when 54 is divided by k? 16 Suppose -z - 5 = -41. Let t = z - -21. What is the remainder when t is divided by 20? 17 Let w(g) = -16g - 29. Let f(o) = -5o - 10. Let n(r) = 17f(r) - 6w(r). What is the remainder when n(5) is divided by 20? 19 Suppose 5h - 80 = 20. Suppose 0 = -2f - 2f + h. What is the remainder when 13 is divided by f? 3 Let w(m) = m*3 + 5m*2 - 2m + 1. Calculate the remainder when 98 is divided by w(-4). 23 Let a(t) = 2t + 2. Let b be a(2). Let n(i) = -i3 + 5i*2 + 7i - 8. Let f be n(b). Calculate the remainder when 32 is divided by 112/10 + f/10. 10 Suppose 4y = -y + 80. Let a = y + 9. Calculate the remainder when a is divided by 9. 7 Suppose -5v + 69 = -46. Let f be -43/(-9)3. Suppose -l + f = -4. Calculate the remainder when v is divided by l. 7 Suppose -3p + 4p - 15 = 0. What is the remainder when p is divided by 4? 3 Suppose -4g - 3 = -43. Suppose -v + 6 = 2v. Suppose -vb - i = -24, 3b + gi - 29 = 5i. What is the remainder when b is divided by 8? 5 Suppose g + 4g = 5w - 105, 3w = 5g + 73. Calculate the remainder when 29 is divided by w. 13 Suppose -4i + 3i = -5. Suppose 0 = 2h - 0h + 3t - 12, it - 4 = 2h. What is the remainder when h is divided by (-1)/2 - 25/(-10)? 1 Let u = 0 + -2. What is the remainder when 57 is divided by 360/27(-3)/u? 17 Suppose 0 = -4r + 6 + 2. Suppose -w + 98 = -5t, -rt - 2t - w - 82 = 0. Let j = t + 33. Calculate the remainder when j is divided by 7. 6 Suppose -2f + 60 = 2g, -f + 4g + 30 = -0f. Let m = f - 24. What is the remainder when 9 is divided by m? 3 Let x(m) = -10m - 17m - 7 + 24m. Calculate the remainder when 30 is divided by x(-6). 8 Let y be (-16)/88 - (-26)/22. What is the remainder when 4/y330/40 is divided by 9? 6 Suppose 0w + t = -4w + 30, -5w - t = -37. What is the remainder when 16 is divided by w? 2 Let y(a) = 8a*2 + 2a + 1. Let c be y(-1). Let d = c + -4. Suppose 0h + 3h - l - 24 = 0, dh = -l + 30. Calculate the remainder when 16 is divided by h. 7 Suppose -4i - 1 + 5 = 0. Let s be 411/i. Suppose -sp + 16 = -0p. What is the remainder when 10 is divided by p? 2 Let f = -6 + 4. Let h be (12/8)/((-1)/f). Suppose -h = -3n + 6, -4j - 3n = -77. Calculate the remainder when 49 is divided by j. 15 Suppose 0o - 3o = -t, 0 = -o. Suppose -3a + 4v + 35 = -2a, -4a + 3v + 192 = t. What is the remainder when a is divided by 13? 12 Suppose 0 = 2h + h + 99. Let f = 46 + h. Calculate the remainder when f is divided by 8. 5 Let p = -3 + 65. Calculate the remainder when p is divided by 33. 29 Suppose 9j - 51 = -8j. Suppose 4x - 32 = -g - 2g, 3g + 5x - 34 = 0. What is the remainder when g is divided by j? 2 Suppose -2n + 3n = 27. Calculate the remainder when n is divided by (((-1)/3)/1)/(3/(-126)). 13 Suppose -3y + 0y = -3i + 24, 0 = 4y - 3i + 33. Let z = y + 21. Let s = z + -7. Calculate the remainder when s is divided by 2. 1 Suppose 2a + 10 = -0a, -105 = 4p + 5a. What is the remainder when p/(-6) - 2/6 is divided by 1? 0 Calculate the remainder when (10/25)/(1/85) is divided by 12. 10 Suppose 8 = -4t + 5m, t + 0 = -2m - 15. Let b = -44 - -123. What is the remainder when 21 is divided by b/7 + 2/t? 10 Let i(f) = -f3 + 1 + 1 + 1. Let y(j) = -11j - 36. What is the remainder when y(-4) is divided by i(0)? 2 Suppose 3r + 46 = 169. What is the remainder when r is divided by 14? 13 Let z = -20 + 44. Calculate the remainder when z is divided by 13. 11 Let w(t) = -4t - 3. Let k be w(-5). Let g = k + 28. Suppose -4i + 107 - 15 = 0. What is the remainder when g is divided by i? 22 Suppose -3r - u + 31 = 0, 5 = -4r + 5r - 5u. What is the remainder when 27 is divided by r? 7 Let k(s) = 2s - 2. Let i(o) = -3o - 7. Let c be i(-5). Calculate the remainder when 35/2c/5 is divided by k(6). 8 Suppose -2o = -106 - 94. What is the remainder when o is divided by 34? 32 Let p(t) = t3 + 7t*2 - 7t + 5. Let s(z) = 2z + 6. Let f be s(-7). Let r be p(f). What is the remainder when (-4 - r)/((-1)/23) is divided by 12? 11 Let a(g) = g3 - 6g*2 + 2g - 1. Let d be a(6). Suppose -5 = -5k - 0. Let j = k + d. What is the remainder when 35 is divided by j? 11 Suppose 3i + 125 = -2i. Let c = -16 - i. Let o(x) = -x*3 +
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260, 2703, 18, 310, 3635, 1340, 407, 260, 24290, 565, 13, 260, 6795, 565, 13, 260 ]	continent’s north-east. And to make it even worse, native animal populations drop wherever the cane toad spreads – due to competition for resources and also the fact that most predators who eat them get poisoned. When threatened, cane toads ooze white poison called bufotoxin from parotid glands on their backs. According to the Global Invasive Species Database, it’s been known to kill cats, dogs, snakes, lizards and even humans. There are programs to try and train animals away from eating cane toads, but Australian crows (Corvus orru) don’t need any of that. These birds have figured out how to get a meal and how not to get poisoned – and now an Australian nature photographer has captured a crow in action: “These clever birds have learnt to roll the toads onto their backs, sometimes doing so repeatedly if the luckless toad tries to hop away. Crows know which bits to eat – fleshy thighs, tongues, intestines – and how to get at these from below without contacting the lethal parts.” It’s probably more a testament to the crows’ cleverness than a solution to the cane toad conundrum.Customer reviews of our Photo Graduation Announcements May 11, 2015Take a close look "We ordered this card for our daughter's High School graduation. The cards printed beautifully, but make sure you look closely at the printed wording side to notice there are markings on the black background. We did not look closely enough and I thought they were smudges. The fault was mine for not looking closely enough, but the rest of the card is beautiful." January 27, 2014Beautiful Card "This was the perfect card at the right price! The pictures turned out great,& it was a very stylish more expensive looking card without the high cost. Love it!" June 12, 2013Great looking "The card looked great, I loved the layout and was overall happy with the quality. We were proud to send it out to family and friends."So, Here’s the “Why” In Tableau, we are easily able to slice and dice the data according to our dimensions thanks to the default manner in which Tableau aggregates the data on our behalf. Therefore, I can simply add any measure and trust the view is appropriate at that level; from an overview, down to the finest level of detail, Tableau aggregates accordingly. But what happens when we have aggregate data, and we need to re-aggregate? For instance, what if I want to categorize and then summarize my sales data at a higher level than what currently exists in my data? As indicated in the picture below, my sales data is actually down to the item level for each customers’ purchase. Let’s say I would like to classify purchasers based on the overall amount they have spent rather than by each individual transaction. I don’t currently have any dimension in the data set that categorizes these sales, but there are a few ways I can create a solution in Tableau. I could create a conditional filter, or perhaps a series of sets for each one of these categories, but each would only allow me to view one category at a time. Most likely, I would build a custom calculation to create a new dimension in Tableau. I decided to create the following calculated field. The following calculation gives me the result I’m looking for; or so I think. This calculation allows me to view the sales classification against the entire data set to see the proportion of all categories at one time, but I wouldn’t be able to view a customer level summary with this calculation because it is performing at the row level, which is per each item sold (added color for emphasis of applied calculation). Although I can view the classification for each item that was sold, I’m interested in what my customer’s total spending level is. For example, if you view Customer #1, the overall sales total just over $19k, but according to our calculation, the sales classification is being made for each item that Customer #1 has purchased, sometimes multiple items per order. “Just remove the Item and Order levels,” you say. Let’s see what happens as a result. Thankfully, and unfortunately in this case, Tableau is still properly applying our row level calculation according to each item every customer has purchased. So, why is there only two entries, and why is one entry over $18k and colored orange according to the $9,999 – $5,000 range? If you look carefully at the previous screen shot, Tableau has summed up all like classifications. We had three items for Customer #1, each item in the $9,999 – $5,000 range, totaling $18,624. The rest were all items at or below the $4,999 threshold. Not exactly the result we intended. The calculation is unable to roll up according to the Customer level. But wait…here’s the great news. We can once again utilize the power of extracts to help for this scenario! So, here’s the “HOW”… In order to fix this, we can create an extract and aggregate the data according to the level that we’re interested in (I hope now you’re now saying to yourself, “So that’s what that check box is for”). First, we simply hide all of the levels of detail that will interfere, or be of finer grain, than the level we are interested in, which happens to be Customer ID. Therefore, if we hide the Item and Order ID, Tableau will aggregate the sales to a higher level, allowing us to see sales by customer (I am hiding all of the unnecessary dimensions for simplicity of the example). From this point, we can create our Extract, making sure to “Aggregate data for visible dimensions.” Now, we can see our calculation applied to the Customer level. Now that our calculation is being applied in the manner in which we were hoping, we can use it more functionally across the data set to see a summary of our customers (below TOP) versus the Item level (below BOTTOM) which skews our summary results and show us every record (item) instead of looking at our customers. Please feel free to comment or email with any questions and/or suggestions on this post. Happy extracting!Martin Smith (figure skater) Martin Smith (born January 14, 1968) is a Canadian former competitive ice dancer. With Jo-Anne Borlase, he is the 1989 NHK Trophy bronze medalist, 1989 Skate America bronze medalist, and 1990 Canadian national champion. With Michelle McDonald, he won the 1991 Canadian national title. Career Early in his career, Smith skated in partnership with Melanie Cole. The two placed fourth at the 1986 World Junior Championships, which took place in December 1985 in Sarajevo, and won the Canadian national junior title the same season. The following season, they competed on the senior level, placing 8th at the 1986 Skate America. In 1987, Smith teamed up with Jo-Anne Borlase. In their second season together, they won bronze at the Canadian Championships. In their third, they took bronze at the 1989 Skate America and 1989 NHK Trophy before winning the national title. They finished 7th at their final event together, the 1990 World Championships in Halifax, Nova Scotia. Smith competed the next two seasons with Michelle McDonald. The two won the 1991 Canadian national title but dropped to third in 1992 and missed out on the Olympics. Smith represented the Kitchener-Waterloo Skating Club (1986) and the Granite Club (1990 to 1992). Competitive highlights With McDonald With Borlase With Cole References Category:Living people Category:Canadian male ice dancers Category:1968 births--! qt:dataset:alltypesorc set hive.explain.user=false; SET hive.vectorized.execution.enabled=true; SET hive.auto.convert.join=true; SET hive.vectorized.execution.mapjoin.native.enabled=true; set hive.fetch.task.conversion=none; -- Using cint and cstring1 in test queries create table small_alltypesorc1a_n1 as select * from alltypesorc where cint is not null and cstring1 is not null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc2a_n1 as select * from alltypesorc where cint is null and cstring1 is not null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc3a_n1 as select * from alltypesorc where cint is not null and cstring1 is null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc4a_n1 as select * from alltypesorc where cint is null and cstring1 is null order by ctinyint, csmallint, c
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]	にシェアを取ってしまい、ひっくり返すことができなかったことからの教訓と言えるだろう。また、政策としてできることとして、とくに中～小規模企業に対するローカライズ支援策（翻訳支援や現地提携企業情報の提供など）を挙げた。ただ、この項は、アイデアが共通しているだけでは著作権による保護を受けることはできず、ある地域（仮にAとする）で最初にサービスインしたタイトル（仮に1とする）がいわゆる“元祖”と受け取られ、他地域（Bとする）でそのタイトル（1）より先にサービスインしたタイトル（仮に2とする）であっても、Aに後から2が参入した場合、どれを“元祖”、どれを“模倣”と捉えるか、あからさまにデータをコピーしている場合でもないかぎり、定義付けが難しい問題ではないかと感じられた。プレミアムフライデーによる経済効果の測定 2017年2月よりスタートしたプレミアムフライデーの効果がスマートフォンゲームアプリ業界でどのように現れているのかを検証した。ランキング上位50タイトルを対象に測定した結果、プレミアムフライデー実施後、売り上げの増加がみられた。野球の観戦者や旅行需要での効果はみられていないが、会社を退社した後、家や外でスマートフォンゲームアプリを遊ぶユーザーが増えたということになる。コンプガチャ規制の政策評価消費者庁の見解による景品表示法の“絵合わせ”にあたるとして、2012年5月に実質禁止されたいわゆる“コンプガチャ（コンプリートガチャ）”。この政策がどのように効果が及んだかを検証したもの。フリーミアムゲームの中で、コンプガチャを実施していたゲーム、通常のガチャを実施していたゲーム、ガチャのないゲームと売り上げとダウンロード数を検証していった結果、コンプガチャの実施/非実施を問わず、ガチャを実施していたゲームの売り上げ/ダウンロード数ともに低下したという結果となった。政策はコンプガチャのみに作用することが望ましかったが、結果はガチャ全般のイメージが悪化し、一時的なゲーム離れを起こしたのみで終わったと考えられるという結果となった。山口真一氏の講演国際大学グローバル・コミュニケーション・センター講師の山口真一氏。 “課金疲れ”の検証：モバイルゲームにおいて、長期に売り上げを最大化する最適APPUはいくらか？モバイルゲームにおいて、KPI（Key Performance Indicators＝目標を達成するための施策がうまくいっているかを確認するための指標）として、“アクティブユーザー数（AU)”、“有料ユーザー数”、“有料ユーザーひとり当たりの単価（ARPPU）”を用いていることが多い。短期の売上高を最大化するには、これらをいかに上げるかを考えればいいが、ヒアリング調査によると、高額を支払ったユーザーがつぎの月に購入を控えるようになったり、サービス自体から離脱するといった行動＝“課金疲れ”がみられることがわかった。これを踏まえた、長期売上高を最大にする最適ARPPUが存在するのではないかという検証が行われた。 2012年9月～2015年4月の182のゲームを対象に得られたパネルデータを分析に用いた結果、前期の消費者支払い行動の集計であるARPPUが売り上げに影響を与えているということがわかったほか、前期の無料ユーザーが増えると今期の売り上げが増加する＝有料ユーザーへの移行がみられるため、単なるコストではなく売り上げに貢献していることや、サービスが長期化すると売り上げは下がっていくこと、2月、9月、10月は売り上げが低く、8月が高い（＝夏休み需要？）といったデータがみられた。また、ARPPUが11754円を超えると売り上げは逆に下がっていく＝“課金疲れ”が見られる結果となった。長期売上高最大化のためには、短期的に売り上げを追い求めるだけでなく、ARPPUを上げすぎない戦略を考える必要があるという結論となった。モバイルゲームがコンソールゲームに与えている代替効果は大きいのか？モバイルゲームの台頭がコンソールゲームを代替し、パラダイムシフトが起きているというが、その効果はどれぐらい大きいのかを検証。ゲームエイジ総研の2014年8月～2015年8月に行われた50000人のアンケート調査データを用いており、据え置き機ではプレイステーション3、Wii、PSP、ニンテンドー3DSをメインとした分析を行った。 PS3→PS4、Wii→Wii U、PSP→プレイステーション Vitaといったゲーム専用機の後継機では代替効果が大きく、携帯ゲーム機と据え置き型ゲーム機での効果は限定的であることが改めて明らかになったほか、スマートデバイスの代替効果については、任天堂ハードと、ソニー・インタラクティブエンタテインメントのハードではユーザー層の違いから代替効果に違いが出た。さらに、据え置き型ゲーム機と携帯型ゲーム機では効果
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3753, 327, 247, 43219, 14, 33647, 369, 3782, 27096, 46823, 187, 187, 8, 18102, 6227, 11388, 26750, 308, 1135, 566, 15, 686, 42, 795, 312, 64, 9995, 2, 309, 476, 10693 ]	grandmother was a Parkinson. Some things I learnt from her— 'The girl known as Mary Jordan was in our service. She had connections in the Navy—her mother was Austrian and so she herself spoke German fluently. 'As you may know, and as your husband certainly knows already, there are certain documents which will shortly be released for publication. 'The present trend of political thinking is that hush-hush, necessary as it is at certain times, should not be preserved indefinitely. There are things in the records that should be made known as a definite part of our country's past history. 'Three or four volumes are due to be published within the next couple of years authenticated by documentary evidence. 'What went on in the neighbourhood of Swallow's Nest (that was the name of your present house at that time) will certainly be included. 'There were leakages—as always there are leakages in times of war, or preceding a probable outbreak of war. 'There were politicians who had prestige and who were thought of very highly. There were one or two leading journalists who had enormous influence and used it unwisely. There were men even before the First World War who were intriguing against their own country. After that war there were young men who graduated from universities and who were fervent believers and often active members of the Communist Party without anyone knowing of that fact. And even more dangerous, Fascism was coming into favour with a full progressive programme of eventual union with Hitler, posing as a Lover of Peace and thereby bringing about a quick end to the war. 'And so on. A Continuous Behind the Scenes Picture. It has happened before in history. Doubtless it will always happen: a Fifth Column that is both active and dangerous, run by those who believed in it—as well as those who sought financial gain, those who aimed at eventual power being placed in their hands in the future. Some of this will make interesting reading. How often has the same phrase been uttered in all good faith: Old B.? A traitor? Nonsense. Last man in the world! Absolutely trustworthy! 'The complete confidence trick. The old, old story. Always on the same lines. 'In the commercial world, in the Services, in political life. Always a man with an honest face—a fellow you can't help liking and trusting. Beyond suspicion. "The last man in the world". Etc., etc., etc. Someone who's a natural for the job, like the man who can sell you a gold brick outside the Ritz. 'Your present village, Mrs Beresford, became the headquarters of a certain group just before the First World War. It was such a nice old-world village—nice people had always lived there—all patriotic, doing different kinds of war work. A good naval harbour—a good-looking young Naval commander—came of a good family, father had been an admiral. A good doctor practising there—much loved by all his patients—they enjoyed confiding their troubles to him. Just in general practice—hardly anyone knew that he had had a special training in chemical warfare—in poison-gases. 'And later, before the Second World War, Mr Kane—spelt with a K—lived in a pretty thatched cottage by the harbour and had a particular political creed—not Fascist—oh no! Just Peace before Everything to save the world—a creed rapidly gaining a following on the Continent and in numerous other countries abroad. 'None of that is what you really want to know, Mrs Beresford—but you've got to realize the background first, a very carefully contrived one. That's where Mary Jordan was sent to find out, if she could, just what was going on. 'She was born before my time. I admired the work she had done for us when I heard the story of it—and I would have liked to have known her—she obviously had character and personality. 'Mary was her own Christian name though she was always known as Molly. She did good work. It was a tragedy she should die so young.' Tuppence had been looking up to the wall at a picture which for some reason looked familiar. It was a mere sketch of a boy's head. 'Is that—surely—' 'Yes,' said Mr Robinson. 'That's the boy Alexander Parkinson. He was only eleven then. He was a grandson of a great-aunt of mine. That's how Molly went to the Parkinsons' in the role of a nursery governess. It seemed a good safe observation post. One wouldn't ever have thought—' he broke off, 'what would come of it.' 'It wasn't—one of the Parkinsons?' asked Tuppence. 'Oh no, my dear. I understand that the Parkinsons were not involved in any way. But there were others—guests and friends—staying in the house that night. The evening in question was the date of a census return. The names of everyone sleeping under that roof had to be entered as well as the usual occupants. One of those names linked up in a significant manner. The daughter of the local doctor about whom I have just told you came down to visit her father as she often did and asked the Parkinsons to put her up that night as she had brought two friends with her. Those friends were all right—but later her father was found to be heavily involved in all that was going on in that part of the world. She herself, it seemed, had helped the Parkinsons in garden work some weeks earlier and was responsible for foxgloves and spinach being planted in close proximity. It was she who had taken the mixture of leaves to the kitchen on the fatal day. The illness of all the participants of the meal passed off as one of those unfortunate mistakes that happen sometimes. The doctor explained he had known such a thing happen before. His evidence at the inquest resulted in a verdict of Misadventure. The fact that a cocktail glass had been swept off a table and smashed by accident that same night attracted no attention. 'Perhaps, Mrs Beresford, you would be interested to know that history might have repeated itself. You were shot at from a clump of pampas grass, and later the lady calling herself Miss Mullins tried to add poison to your coffee cup. I understand she is actually a granddaughter or great-niece of the original criminal doctor, and before the Second World War she was a disciple of Jonathan Kane. That's how Crispin knew of her, of course. And your dog definitely disapproved of her and took prompt action. Indeed we now know that it was she who coshed old Isaac. 'We now have to consider an even more sinister character. The genial kindly doctor was idolized by everyone in the place, but it seems most probable on the evidence that it was the doctor who was responsible for Mary Jordan's death, though at the time no one would have believed it. He had wide scientific interests, and expert knowledge of poisons and did pioneering work in bacteriology. It has taken sixty years before the facts have become known. Only Alexander Parkinson, a schoolboy at the time, began having ideas.' ' _Mary Jordan did not die naturally,_ ' quoted Tuppence softly. ' _It must have been one of us._ ' She asked: 'Was it the doctor who found out what Mary was doing?' 'No. The doctor had not suspected. But somebody had. Up till then she had been completely successful. The Naval commander had worked with her as planned. The information she passed to him was genuine and he didn't realize that it was mainly stuff that didn't matter—though it had been made to sound important. So-called Naval plans and secrets which he passed to her, she duly delivered on her days off in London, obeying instructions as to when and where. Queen Mary's Garden in Regent's Park was one, I believe—and the Peter Pan statue in Kensington Gardens was another. We learned a good deal from these meetings and the minor officials in certain embassies concerned. 'But all that's in the past, Mrs Beresford, long, long in the past.' Colonel Pikeaway coughed and suddenly took over. 'But history repeats itself, Mrs Beresford. Everyone learns that sooner or later. A nucleus recently reformed in Hollowquay. People who knew about it set things up again. Perhaps that's why Miss Mullins returned. Certain hiding-places were used again. Secret meetings took place. Once more money became significant—where it came from, where it went to. Mr Robinson here was called in. And then our old friend Beresford came along and started giving me some very interesting information. It fitted in with what we had already suspected. Background scenery, being set up in anticipation. A future being prepared to be controlled and run by one particular political figure in this country. A man with a certain reputation and making more converts and followers every day. The Confidence Trick in action once again. Man of Great Integrity—Lover of Peace. Not Fascism—oh no! Just something that looks like Fascism. Peace for all—and financial rewards to those who cooperate.' 'Do you mean it's still going on?' Tuppence's eyes opened wide. 'Well, we know more or less all we want and need to know now. And that's partly because of what you two have contributed—the operation of a surgical nature on a rocking-horse was particularly informative—' 'Mathilde!' exclaimed Tuppence. 'I _am_ glad! I can hardly
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20, 15, 1281, 295, 9, 72, 10, 426, 305, 424, 19, 15, 1281, 1269, 9, 82, 10, 426, 428, 20, 11, 79, 9, 82, 10, 559, 256, 9, 82, 481, 9985, 253, 1273, 4309, 273, 1269, 9, 69, 10, 8772, 277, 15, 187, 14, 740, 187, 1466, 295, 9, 89, 10, 320, 253, 1273, 4309, 273, 428, 89, 428, 2145, 16, 21, 11, 89, 424, 21, 428, 577, 559, 470, 11, 89, 424, 19, 428, 3127, 16, 740, 11, 89, 424, 22, 559, 470, 11, 89, 424, 20, 15, 1737, 310, 253, 2626, 4309, 273, 295, 9, 71, 10, 8772, 269, 32, 187, 14, 20438, 187, 1466, 298, 9, 87, 10, 320, 253, 806, 4309, 273, 1458, 11, 87, 424, 22, 559, 470, 11, 87, 424, 20, 559, 7346, 559, 470, 11, 87, 424, 21, 428, 6931, 16, 19, 11, 87, 424, 19, 559, 470, 11, 87, 15, 9985, 253, 1273, 4309, 273, 298, 9, 78, 10, 8772, 278, 15, 187, 18104, 11, 78, 424, 19, 187, 1466, 298, 9, 83, 10, 320, 253, 806 ]	Find the second derivative of x(t) wrt t. 60t3 - 96t + 4 Let u(g) = 138 + 0 + 207g - 440g. Let m(j) = -228j + 139. Let h(n) = 3m(n) - 4u(n). Differentiate h(s) with respect to s. 248 Let l = 136 - 62. Let t = 76 - l. What is the first derivative of 5c*t + 10c*2 - 14 - 2c*2 + 11c*2 wrt c? 48c Let c = 37 - 35. Find the third derivative of -1330b5 + 96b*c + 672b*5 + 669b*5 wrt b. 660b*2 Let h be 0/((6 - -4)-1). Let z(o) be the second derivative of -6o + h - 11/6o*3 - 11o*2. What is the first derivative of z(r) wrt r? -11 Let j = -69 + 74. Suppose 5o + 25 = ji, 0 = 8i - 3i + 3o - 1. Find the third derivative of 2x6 + 23x*6 - 10x*2 - 4x2 + xi wrt x. 3000x3 Let v(u) be the first derivative of 47 - 41u - 1/2u2 - 23u*3. Find the second derivative of v(j) wrt j. -138 Let p(v) = 5862v*2 + 3614. Let z(o) = 43966o*2 + 27113. Let r(a) = -38p(a) + 5z(a). Find the first derivative of r(d) wrt d. -5852d Let h(g) be the first derivative of 103g6/30 + 15g*3/2 - 86g + 11. Let b(a) be the first derivative of h(a). What is the second derivative of b(n) wrt n? 1236n2 Suppose 32d = 31d. Suppose n + 1 - 19 = d. What is the second derivative of -237f*4 + 222f*4 + f - nf wrt f? -180f2 Suppose -10p = -19p + 27. Find the third derivative of 17o*5 - 15o*3 - 14o*2 + 10o*p + 7o*3 wrt o. 1020o*2 + 12 Suppose 0 = v - 2k - 6, -4v - k - 4k = -24. Find the third derivative of 4385f - 4385f - v - 3f2 - 22f*5 wrt f. -1320f*2 Let r(o) be the first derivative of 4066o*3/3 - 3o*2 + 222o + 7135. What is the second derivative of r(t) wrt t? 8132 Let n(a) be the first derivative of 5063a3/3 + 3179a + 589. What is the derivative of n(w) wrt w? 10126w Let x(o) = -o2 + 11o + 7. Let y be x(12). Let j be 22/6 + y/((-30)/(-4)). Find the third derivative of 20kj + 17k*3 - 25k*5 - 37k*3 - 34k*2 wrt k. -1500k*2 Find the second derivative of -29p*3 + 45p*3 - 16p*3 - 544p - 253p4 - 1908p wrt p. -3036p2 Let m(z) be the first derivative of -2z*5/5 - 53z*4/4 + 10z*3/3 - 1008z*2 + 468. Find the second derivative of m(v) wrt v. -24v*2 - 318v + 20 Suppose 0 = -3r - 3w, -2w + 3w = -5r. What is the second derivative of 72g*2 + 34 - 8g + rg + 6g + 0g wrt g? 144 Let h(v) be the second derivative of -7/2v*2 - 85v + 0v3 - 2 - 17/3v*4. Differentiate h(t) wrt t. -136t Let a = 30 + -28. Suppose -7w + aw = -5o - 545, -4w + 2o = -438. Find the second derivative of -2 - wz*4 + 11z + 2 + 119z4 wrt z. 108z*2 Let l(z) = -33z*4 - 15z*2 + 122z - 54. Let u(p) = -16p4 - 6p*2 + 60p - 27. Let h(f) = 5l(f) - 9u(f). Find the second derivative of h(r) wrt r. -252r2 - 42 What is the third derivative of -646x*2 + 524x*2 - 1439x*2 + 1155x*5 + 215x*5 wrt x? 82200x*2 Let z(r) be the first derivative of -6131r*5/5 - 5622r + 4489. Differentiate z(f) with respect to f. -24524f3 Let g be (-14/14)/(1/(-49)). Suppose -g = 6v - 13v. Differentiate -73h2 + 37h*v + 41 - 39h*3 + 36h*2 wrt h. -117h*2 Let l(b) be the third derivative of -152b*7/105 - 131b5/60 - b3 - 691b2. Find the third derivative of l(h) wrt h. -7296h Suppose 4l = y + 27 - 8, 12 = -4y. Suppose -26 = -lr - 18. Find the third derivative of 30 + 12t*r - 7t*6 - 30 wrt t. -840t*3 Let f(i) = -i. Let b(t) = -8t + 8. Suppose -2g + 9 = -g + 3n, 2g = -4n + 14. Let q(j) = gf(j) + b(j). Differentiate q(o) wrt o. -11 Let p(c) be the third derivative of -989c5/60 - c4/8 - 103c3/3 + 1478c*2. What is the second derivative of p(w) wrt w? -1978 Let m be -292/(-10) + (-117)/(-585). Find the third derivative of -250qm - 5q + 5q + 290q*6 + 141q*2 wrt q. 4800q*3 Let l = 721 + -595. What is the derivative of -2184y + 4440y + l - 2217y wrt y? 39 Let l(s) = 25s2 - 18s - 1770. Let x(p) = -24p2 + 19p + 1767. Let b(v) = -7l(v) - 6x(v). Differentiate b(r) wrt r. -62r + 12 Let s(c) be the first derivative of -7/2c*2 + 11 + 0c - 2/3c3. Let n(g) = g2. Let x(q) = -3n(q) + s(q). Find the second derivative of x(d) wrt d. -10 Let n(x) be the second derivative of -x - 13/4x4 - 4 + 0x*2 - 21/10x*5 + 0x*3. What is the third derivative of n(f) wrt f? -252 Let l(v) be the first derivative of 15v*5 + 0v*3 + 120 + 0v*4 - 39/2v*2 + 0v. Find the second derivative of l(m) wrt m. 900m*2 Let l(r) be the first
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14, 44, 3288, 2065, 66, 480, 33202, 562, 273, 634, 1481, 15, 187, 187, 510, 2159, 13, 320, 13073, 13, 285, 38754, 21101, 10364, 3196, 15, 844, 89, 2146, 2870, 932, 247, 15589, 17371, 5818, 432, 4377, 20473, 14, 34, 13107, 14, 44, 1240, 3767, 434, 26908, 16764, 34779, 15, 831, 19610, 5239, 253, 22437, 26908, 434, 29921, 278, 14661, 30739, 312 ]	with the help of two guinea pigs - one real, one robotic. Chip 'n Dale Rescue Rangers: Volume 2 DVD DISC 1 Chip and Dale find themselves in the middle of a messy crime in which their police friends are falsely accused. Using the tricks they've learned from careful study of police-work, it's up to them to ensure justice and retrieve a stolen ruby from Fat Cat With all five crime-fighters together at last, the pursuit of Fat Cat and his evil owner, Claudaine, kicks into high gear. Meanwhile, Professor Nimnul makes things more complicated for the gang, who are forced to battle the elements. In Hawaii, the Rangers find themselves mixed up in the initiation of a new queen who happens to look just like Gadget. The queen-to-be tricks Gadget into taking her place in some dangerous royal hazing. DISC 1 1. "Catteries Not Included" (22:43) (Originally aired March 6, 1989) The search for a missing kitten named Spunky leads the gang to an underground operation where robotic dogs are terrorizing dark alleys and kidnapping cats for Professor Nimnul. 2. "Three Men and a Booby" (22:44) (Originally aired April 30, 1989) A grocery store visit brings the gang face to face with a distressed purple booby (that's a bird), who's desperately trying to find her baby egg. The trail takes the Rescue Rangers to a grouchy little man named Mr. Humpty. 3. "The Carpetsnaggers" (22:46) (Originally aired May 7, 1989) 4. "Piratsy Under the Seas" (22:40) (Originally aired March 5, 1989) Dale's disregard for tidiness leaves him in the back of a garbage truck. When the rest of the gang attempts to rescue him, they wind up afloat on a junk barge. Not long after, they encounter a band of pirates in possession of a tidy treasure. In pursuit of Fat Cat and the legendary Maltese Mouse, Chip and Dale wreck the treehouse of a squirrel family. To make up for it, they agree to babysit the two squirrel children while their mother takes care of the place. Teenaged Tammy's unrequited crush for Chip has her running off to the city, throwing the Rescue Rangers among Fat Cat's crowd and forcing Chip and Dale to perform in drag! 6. "Flash the Wonder Dog" (22:44) (Originally aired March 19, 1989) To bring down beloved television star Flash the Wonder Dog, Fat Cat and his henchmen dress up in his costume and perform random acts of badness. Soon, the town is buzzing with bad vibes for Flash and the studio is replacing the canine with his cockatoo sidekick. Meanwhile, Dale gets a sobering meeting with his TV hero. The Rescue Rangers become involved in a bit of domestic drama when they encounter Roger Baskerville, a snooty mansion resident who wants nothing to do with his brother and his sheepdog, the rightful owners of the estate. Every turn seems to remind Chip of the literary adventures of the crafty detective Sureluck Jones and he uses his knowledge to try to outwit Baskerville and save the sheepdog. Monterey Jack's world-traveling father Cheddarhead Charlie stops by and helps the Rescue Rangers as they try to figure out a dining oddity at a seafood joint. Their trail leads them to Fat Cat and another evil plan. 9. "Risky Beesness" (22:44) (Originally aired April 23, 1989) A queen bee is quite perturbed when her entire swarm simply disappears. An enchanted Zipper and the rest of the Rescue Rangers are her only hope, and they track the bees down to an extermination company worker with dreams of rocking and rolling. DISC 2 10. "Bearing Up Baby" (22:42) (Originally aired May 14, 1989) The Rescue Rangers go vacationing in the woods. A little boy named Jeremy ditches his parents and befriends "fuzzies" small (the Rescue Rangers) and big (playful brown bear Humphrey) alike. His father isn't quite as charmed by the boy's new pal and leads a search party to hunt the large bear. 11. "Out to Launch" (22:46) (Originally aired March 26, 1989) The Rescue Rangers' exploration of a space station leads to big time adventure when Chip and Dale get launched into orbit while inside an astronaut suit. Soon, they get a first-hand look at outer space when they fall out of the shuttle. 12. "Dale Beside Himself" (22:48) (Originally aired March 12, 1989) An Earth-loving, shape-shifting alien makes himself look exactly like Dale. Having a powerful clone makes everyday tasks easier for the goofy chipmunk, but the aliens wears out his welcome when he tries to replace Dale. 13. "Kiwi's Big Adventure" (22:46) (Originally aired April 2, 1989) The kiwis, a tribe of primitive birds, steal the Rescue Rangers' plane but can't figure out how it works. The Rangers' attempts to retrieve the plane include a little jealousy and a lot of coddling when Dale "stubs his toe" and Gadget nurses him to an extreme. 14. "A Lad in a Lamp" (22:45) (Originally aired October 3, 1989) Monterey Jack happens upon Aladdin's magic lamp, but his newfound power irritates his friends and his third wish leaves him at the genie bound to serving the lamp's new masters: Fat Cat and his cronies. 15. "Battle of the Bulge" (22:40) (Originally aired October 9, 1989) After his appetite nearly gets him caught, Monterey Jack vows to diet and exercise. Meanwhile, the Rangers trace a series of heists marked by seedy remains back to Fat Cat and his new hired help, a trio of Jamaican fruit bats. 16. "Ghost of a Chance" (22:38) (Originally aired October 10, 1989) Fat Cat and his henchmen plan to steal the crown jewels of England, but the Rescue Rangers are there to try to stop them. While in the Tower of London, Monterey Jack discovers his brave ancestor Sir Colby was really a coward -- the mouse's ghost is no different and, suddenly, neither is Monty himself. The Rescue Rangers' day at the zoo ends with them picking up the case of the missing peanuts. After widespread interrogations, though, Chip and Dale are the prime suspects with the perturbed elephants and monkeys. But might the suspicious behavior of a couple of homesick Asian pandas be a lead? The Rescue Rangers go out for a night at the movies, only it turns out to be a night at the opera, which turns out to be a chance for gang to live up to their name when they encounter Sewernose de Bergerac, an envy-filled crocodile with a penchant for hand puppets. When the croc tries to sabotage the stage, the Rangers respond in appropriately theatrical fashion. DISC 3 19. "The Luck Stops Here" (22:41) (Originally aired October 6, 1989) Gadget falls into the possession of Clyde Cosgrove, a highly superstitious inventor who decides that the lavender-clad mouse is his new good luck charm. Gadget must overcome Cosgrove's vengeful cat and the nutty experimenter's high stress efforts to make a splash at a quickly approaching kitchen appliance convention. Feeling small and helpless, Zipper's self-confidence gets a boost when he is inadvertently among a group of pill bugs that Professor Nimnul zaps with his Gigantico Ray gun. While Nimnul uses the now-enormous pill bugs to convince mankind that demanding aliens in search of gold are among them, the bigger and buffer Zipper wows his fellow Rescue Rangers and tries to thwart the Professor's plans. A young boy's missing toy train doesn't warrant much attention from the police, but it does garner the Rescue Rangers' efforts. They discover the train is part of a bank-robbing scheme concocted by . . . Fat Cat, who else? 22. "The Case of the Cola Cult" (22:51) (Originally aired October 17, 1989) Fate brings the Rescue Rangers into contact with the Cola Cult, a group of rodents who worship a bright, catchy, musical commercial for Koo-Koo Cola and christen themselves with fruit soda of the same brand. When Gadget experiences some problems, she considers turning to them, until she learns the truth about one of their leaders. Not only is this likely the weirdest "Rescue Rangers" episode ever made, it could be the strangest half-hour of animation ever. That puts it in the same league as the giant crossover anti-drug special "Cartoon All-Stars to the Rescue." Good luck getting that Koo-Koo Cola jingle out of your head. The short, bearded, and greedy archaeologist Dr. Wexler steals a jeweled ring from King Nut-Ahn-Kahmen's tomb expecting diamonds. This theft sets the Egyptian tomb's guardian mummy Hiram
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327, 697, 8135, 5742, 22294, 281, 10564, 14335, 1341, 689, 13002, 9276, 2300, 14, 18, 1254, 35, 1731, 1656, 8714, 36211, 13, 253, 14335, 46862, 476, 320, 12059, 407, 18533, 285, 4499, 6083, 285, 778, 320, 247, 2097, 273, 18723, 5835, 281, 253, 27102, 1955, 281, 12059, 25566, 1254, 35, 1630, 2947, 35, 1619, 1656, 5131, 11172, 2538, 2486, 2494, 11179, 31430, 13, 285, 894, 2471, 275, 253, 2839, 5508, 302, 6182, 91, 3750, 6616, 970, 12551, 1988, 1254, 35, 1717, 1656, 3840, 13, 7590, 5036, 18620, 13, 285, 26802, 23753, 369, 2540, 275, 253, 6521, 30781, 1563, 897, 273, 12551, 1988, 1254, 35, 1229, 1656, 21461, 13, 253, 8789, 273, 38481, 2173, 353, 2925, 281, 1982, 4499, 25267, 778, 6635, 4408, 2173, 4499, 25267, 533, 13, 627, 403, 14122, 29765, 285, 20506, 4723, 326, 1543, 432, 253, 5678, 897, 273, 12551, 1988, 285, 18039, 33035, 517, 15, 187, 187, 53, 360, 641, 403, 7976, 2220, 253, 4702, 273, 28522, 14, 87, 405, 1241, 323, 4821, 3116, 15, 8758, 26681, 13, 475, 249, 8427, 2992, 6979, 273, 35244, 1177, 310, 6685, 1774, 323, 12488, 8837, 15, 5595, 15538, 13, 436, 16000, 247, 2097, 273, 9273, 3270, 14, 38335, 32991, 275, 38873, 3210, 285, 3382, 4893, 15, 2053, 6979, 5609, 671, 9659, 1029, 14, 21061, 13, 1936, 45558, 20215, 273, 4502, 11172, 414, 15, 496, 247, 38873, 1566, 273, 5988, 2923, 310, 2011, 326, 27972, 342, 643, 24223, 5576, 5593, 273, 2614, 2685, 13, 534, 778, 2085, 3687, 7340, 281, 253, 2494, 9210, 1291, 1177, 275, 1524, 673, 1254, 35, 2405, 1656, 380, 43427, 273, 4502, 28522, 14, 87, 405, 1241, 3890, 11172, 894, 14335, 3116, 2803, 6437, 374, 313, 12695, 13826, 19, 481, 530, 4280, 12761, 42646, 556, 644, 342, 33502, 281, 3270, 16197, 13826, 19, 452, 644, 908, 281, 956, 28038, 275, 247, 38873, 24599, 1566, 323, 5988, 8837, 1254, 35, 1237, 1656, 496, 247, 1966, 35032, 22835, 1566, 13, 516, 1906, 17384, 10888, 34957, 14, 19, 10456, 273, 48448, 8837, 9578, 342, 253, 4499, 14, 35465, 18533, 2460, 1254, 35, 1610, 1656, 380, 6979, 273, 28038, 310, 7976, 2220, 253, 2048, 273, 4502, 390, 14335, 9588, 824, 347, 16197, 13826, 19, 15, 380, 2048, 273, 16197, 13826, 19, 778, 320, 4778, 13, 7293, 2220, 253, 3116, 3924, 16, 3281, 285, 275, 7497, 13, 49556, 1319, 15, 2053, 6979, 5609, 671, 9659, 1029, 14, 21061, 13, 1936, 45558, 20215, 273, 4502, 11172, 414, 15, 380, 11839, 273, 1563, 23199, 6437, 285, 7601, 30447, 347, 247, 10705, 273, 14335, 12974, 310, 717, 2881, 5183, 275, 436, 2929, 15, 187, 187, 688, 15976, 13344, 13097, 4702, 275, 253, 2798, 13, 3998, 390, 275, 247, 10844, 2670, 310, 253, 47947, 273, 11172, 2728, 15, 33034, 13344, 13097, 310, 271, 1774, 2898, 273, 12551, 1988, 285, 1982, 15, 3506, 68, 895, 36270, 13, 534, 25153, 44377, 3719, 67, 16, 8296, 66, 6437, 369, 33502, 281, 12551, 1988, 285, 253, 37013, 27892, 7278, 253, 2460, 273, 18571, 13344, 13097, 475, 249, 8427, 11, 8088, 35, 1706, 1656, 496, 4499, 13, 1982, 285, 1982, 4280, 476, 320, 908, 275, 5019, 281, 2740, 7419, 10290, 25180, 502, 1502, 1254, 35, 1671, 1656, 496, 253, 17876, 2472, 13, 1982, 285, 4499, 5570, 497, 6828, 1411, 253, 32142, 8070, 17716, 15, 2091, 31113, 2646, 369, 11966, 13, 253, 17716, 369, 15715, 4686, 407, 271, 247, 13344, 13097, 1254, 35, 1812, 1656, 2053, 6667, 17093, 253, 31471, 275, 12488, 13344, 13097, 347, 973, 347, 24635, 13344, 13097, 281, 15582, 2614, 2685, 281, 247, 2303, 15411, 15, 380, 2957, 273, 11172, 1159, 326, 359, 2540, 275, 436, 1263, 18303, 253, 20506, 4723, 326, 476, 320, 5802, 15, 187, 187, 3252, 3016, 6979, 273, 14215, 285, 10844, 24908, 310, 6685, 4217, 5853, 281, 2460, 23861, 4702, 285, 11179, 869, 1371, 15, 34820, 1216, 494, 23861, 310, 271, 18571, 15411, 326, 556, 247, 33882, 323, 31430, 285, 13344, 13097, 4702, 15, 8019, 3016, 285, 4499, 5570, 16000, 253, 24426, 273, 16016, 66, 16016, 26606, 4038, 285, 247, 5019, 273, 11764, 5161, 13, 1729, 9544, 285, 9039, 1877, 778, 1361, 4271, 253, 38073, 954, 2779, 281, 31430, 1254, 35, 1787, 1656, 187, 187, 2838, 87, 792, 29940, 476, 4354, 320, 27130, 407, 18533, 8368, 273, 253, 2798, 15, 380, 2494, 27892, 7278, 253, 2460, 273, 253, 36848, 2403, 352, 6927, 281, 4271, 13344, 13097, 13, 10173, 253, 4644, 273, 47378, 2614, 285, 31986, 3402, 3200, 15, 2053, 5164, 2175, 403, 9560, 323, 253, 3382, 20215, 273, 1363, 1254, 35, 1839, 1656, 187, 187, 2512, 403, 34126, 5012, 5001, 253, 1055, 12551, 1988, 327, 1966, 10177, 1159, 1254, 35, 1867, 1656, 367, 677, 290, 13267, 41465, 313, 10201, 6072, 10, 497, 4879, 275, 253, 1966, 2798, 1254, 35, 1449, 1656, 308, 1658, 40341, 308, 369, 19099, 369, 2326, 342, 12551, 1988, 2299, 13, 627, 497, 642, 4016, 46409, 4342, 497, 2326, 1254, 35, 3156, 1656, 496, 271, 643, 1263, 13, 642, 2544, 497, 2326, 275, 22605, 6072, 13, 308, 1658, 40341, 309, 13, 17939, 13, 17939, 14, 9180, 275, 253, 1966, 2798, 1254, 35, 2945, 1656, 187, 187, 688, 247, 38873, 1566, 970, 253, 2839, 2798, 13, 22605, 6072, 13, 285, 2494, 26954, 23753, 369, 4879, 342, 12551, 1988, 1254, 35, 3079, 2947, 35, 2031, 1656, 27628, 13, 2494, 10429, 497, 2326, 1872, 11220, 342, 10142, 23608, 684, 2164, 3038, 1501, 5445, 275, 253, 2839, 2798, 1254, 35, 2031, 2947, 35, 1857, 1656, 496, 5253, 5798, 12306, 1566, 13, 1982, 285, 1982, 4280, 4950, 18560, 4723, 275, 253, 8105, 273, 6773, 15, 27628, 13, 436, 369, 247, 1524, 673, 6803, 273, 253, 4723, 13, 534, 369, 1534, 1254, 35, 2950, 1656, 3824, 1543, 432, 436, 1263, 403, 5185, 342, 11172, 4723, 326, 778, 8162, 281, 253, 38369, 6358, 2326, 475, 249, 8427, 4556, 187, 187, 48623, 15060, 497, 12021, 281, 1097, 1982, 285, 12551, 1988, 13, 285, 10177, 38369, 6358, 497, 5802, 15, 330, 405, 318, 273, 1982, 1971, 13891, 253, 1055, 15, 1723, 13, 642, 24394, 1055, 369, 2326, 1254, 35, 2504, 1656, 18194, 15060, 497, 4127, 342, 18533, 285, 12551, 1988, 13, 285, 253, 5771, 369, 5480, 323, 27913, 1783, 15, 380, 760, 3320, 598, 14, 10088, 369, 6315, 280, 44927, 511, 13, 594, 627, 369, 417, 11360, 3320, 9953, 1254, 35, 2385, 1656, 187, 187, 11244, 273, 18533, 4499, 6083, 13, 9841, 14, 35208, 2494, 67, 35308, 14, 3169, 3580, 534, 403, 11966, 20368, 4087, 281, 7278, 253, 18533, 2460, 3290, 13, 1246, 747, 7881, 342, 2743, 281, 3382, 5252, 984, 273, 253, 12171, 27009, 5621, 273, 48450, 9605, 3535, 4269, 407, 253, 5016, 273, 18533, 342, 253, 2494, 27892, 15, 2053, 27009, 5621, 476, 4723, 253, 43427, 285, 6032, 6616, 273, 253, 11172, 3402, 15, 380, 2303, 3110, 3072, 326, 778, 320, 7329, 281, 2494, 67, 35308, 16, 503, 6230, 517, 310, 1781, 285, 7788, 281, 1756, 347, 747, 4893, 285, 747, 3580, 275, 436, 966, 403, 3715, 15, 187, 187, 2214, 1650, 13, 2559, 25566, 1955, 281, 4499, 5570, 14, 6367, 11172, 4723, 476, 5347, 1025, 2220, 253, 7439, 1037, 281, 7257, 3608, 285, 643, 1781, 8094, 2439, 43427, 15, 1723, 13, 271, 10021, 2362, 326, 778, 2826, 432, 2494, 67, 35308, 14, 6367, 11172, 10429, 778, 320, 253, 17000, 390, 17680, 273, 49667, 10005, 15, 3932, 436, 36453, 310, 1146, 2783, 323, 6742, 273, 5835, 285, 3608, 13, 271, 1014, 4067, 3110, 3072, 313, 10002, 8927, 574, 642, 13440, 2728, 10, 588, 320, 7329, 281, 1048, 14, 3945, 10502, 15, 3813, 13, 352, 310, 4619, 281, 4271, 253, 18533, 285, 2494, 67, 35308, 5445, 2515, 534, 2847, 4723, 281, 253, 11172, 43427, 285, 3653, 1880, 2494, 67, 35308, 14, 6367, 11172, 4723, 5459, 253, 2495, 273, 32317, 275, 4236, 7625, 15, 187, 187, 2512, 403, 2067, 7364, 275, 253, 1246, 1263, 27, 3973, 13, 352, 369, 2684, 475, 911, 8427, 11, 762, 4228, 2515, 342, 642, 2614, 2685, 15, 6347, 13, 760, 581, 4719, 273, 12551, 1988, 369, 7091, 15, 496, 4321, 2175, 313, 42038, 13, 33115, 13, 285, 16865, 41649, 283, 2922, 28, 1254, 35, 23, 2947, 35, 805, 2947, 35, 1867, 2947, 35, 2537, 5413, 253, 2494, 67, 35308, 4719, 17751, 432, 470, 15, 520, 6, 281, 374, 6, 285, 13493, 33948, 7492, 23575, 369, 2326, 387, 337, 7739, 496, 776, 3368, 13, 359, 908, 337, 6, 12551, 1988, 13, 594, 359, 403, 970, 6299, 326, 403, 5185, 342, 2045, 789, 15, 496, 3382, 897, 13, 253, 8521, 12768, 2491, 432, 470, 15, 22, 281, 608, 13361, 273, 12551, 1988, 43861, 275, 247, 884, 1054, 2180, 15, 187, 187, 2214, 841, 2175, 13, 359, 908, 247, 374, 21865, 1982, 5149, 19693, 247, 1740, 14, 16441, 10541, 12948, 948, 8287, 247, 41381, 30116, 4438, 285, 1907, 271, 16432, 273, 337, 15, 26, 13, 253, 4869, 4758, 2130, 327, 247, 3382, 6979, 3943, 15, 733, 310, 417, 2590, 1880, 2074, 2538, 812, 2826, 387, 16432, 2193, 1679, 685, 337, 15, 26, 15, 187, 187, 688, 6452, 13, 374, 21865, 1982, 342, 271, 16432, 273, 337, 15, 26, 285, 337, 6, 12551, 1988, 12059, 22170, 285 ]	in vivo* as well, atherosclerotic lesions may be at risk during US imaging. Optison, in conjunction with US, has been used for gene therapy, drug delivery, angiogenesis studies, imaging vascular injury and evaluating cardiac function. As with any therapy, there are often untoward effects that need to be balanced the potential benefits. Given that there is the potential for widespread collateral effects, preclinical evaluation of ultrasound contrast agents is warranted which is consistent with the results presented in Figures [3](#F3){ref-type="fig"}, [5](#F5){ref-type="fig"}, [6](#F6){ref-type="fig"} and [7](#F7){ref-type="fig"}. The goal of US directed gene therapy is to identify and transfect selected anatomical structures with the gene(s) of interest. Vascular beds are ideal targets given the relative ease in identification and the delivery of the DNA of interest to the relevant tissues. The transfer of genetic material such as plasmid into a cell requires the brief disruption of the membrane. Additionally, signaling pathways such as ERK are activated and may play a role in the eventual expression of the transfected DNA, probably through mechanical sensing via integrins. US activates ERK ½ signaling via rock in skin fibroblasts \[[@B18]\]. Both endothelial cells and smooth muscle cells can be transfected with plasmids by Optison and US \[[@B19]\]. C-myc expression was decreased following transfection with anti-sense morpholino oligomers in porcine arteries treated ex vivo\[[@B20]\]. Neointimal proliferation was inhibited following balloon injury when anti-sense p53 plasmids or decoy E2F decoy oligo nucleotides, Optison and ultrasound were used to transfect rat carotid arteries \[[@B21],[@B22]\]. The contractile response to prostaglandin was reduced in porcine carotid arteries that were transfected with eNOS ex vivo\[[@B23]\]. Plasmid DNA and viruses can be transduced into skeletal muscle through an intra vascular route using US and US contrast agents \[[@B24]\]. In sum, the use of both Optison and US enhances the nonviral gene transfer is an alternative to using viral vectors \[[@B25]\]. While these studies focused upon transfer of genetic material, there was no attempt to evaluate untoward thrombus formation. Inflamed endothelial cells express cell adhesion molecules such as Intracellular adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM). Both ICAM and VCAM can be used to image inflammation and the inflamed tissue can be targeted for in vivo drug delivery as well. A gas-filled microbubble with anti-ICAM-1 antibody on its shell specifically binds to activated endothelial cells over expressing ICAM-1 \[[@B26]\]. Significantly, the endothelial BBB can be altered by ultrasound and contrast agents and may be a means of delivering drugs to the CNS due to altered permeability \[[@B27],[@B28]\]. Other vascular effects include micro vessel rupture, and cell death in the rat spinotrapezius muscle using Optison \[[@B29]\]. Further, petechiae, and capillary leakage was observed in the mouse abdomen following use of Optison \[[@B30]\]. Clearly, the coupling of integrin specific MAB to US contrast reagents may generate tissue specific contrast reagents but, there are nonspecific and collateral damage that results from the combined use of Optison and Ultrasound. Tumors are dependent upon the formation of neo-vessels for continued growth. Noninvasive, in vivo, imaging of vasculature is extremely important for identifying tumors. Most importantly, this permits a means of screening anti-tumor regimens in preclinical models and clinical applications. These imaging techniques also permit high-resolution, volumetric assessments of tumor vascularity. In a preclinical model of breast cancer is shown that correlates with other ultrasonographic measures of blood flow, which may provide greater sensitivity to the microvasculature in real time \[[@B31]\]. The endothelium of tumor neo-vessels express vascular cell endothelial growth factor receptor 2 (VEGFR2). UCA MicroMarker has been with conjugated to anti VEGFR2 have been used to follow angiogenesis in a preclinical murine model for breast tumors \[[@B32]\]. In a human xenograft melanoma model, immuohistochemical COX-2 staining of excised tumors correlated with the contrast-enhanced ultrasound image \[[@B33]\]. The imaging of angiogenesis is dependent upon the expression of tumor or endothelial markers such as VEGFR2. The expression of VEGFR2 may be variable, depending upon the growth stage/size and in humans, clonality. These imaging techniques also permit high-resolution, volumetric assessments of tumor vascularity. The utility of following VEGF receptor and signaling kinases as a marker of endothelial integrity is amply demonstrated in this paper. Inappropriate thrombus formation in the heart, brain or in a peripheral site is the hallmark of vascular disease. Imaging thrombus is an important application of Optison and US. Abciximab, which recognizes glycoprotein IIb/IIIa receptor was conjugated to Optison and the immuno bubbles enhance the image of arterial thrombus in vivo\[[@B34]\]. In contrast, US and USCA can be used in combination to break apart moderate sized clots \[[@B35]\]. In the rabbit ear, US and contrast agent were directed against the auricular vein. When fibrinogen was administered, the vein was occluded by an a thrombus \[[@B36]\]. These examples illustrate the usefulness in identifying thrombus as well as inducing thrombus to inhibit blood flow to a target lesion. The loss of vascular function that we observed in this study illustrates the collateral damage that can be induced. IVUS imaging of coronary and peripheral arteries is extremely useful technique to image plaque formation and vessel patency. Vulnerable plaque is an arterial lesion that has a propensity for rupture and thrombus formation. IVUS and contrast agent permits the visualization of vasa vasorum density and a combination of lipid core, cap thickness and calcification may help identify the plaques most likely to rupture \[[@B37]\]. Valvular stenosis can easily be visualized by ultrasound examination of the heart. The micro bubbles enhance the image of the ventricle making it easier to identify thrombus, calculate the volume of ejected blood and visualize wall motion. These functional studies are crucial for the clinical assessments of patients \[[@B38]\]. There are contradictory reports regarding the effect Optison on human cardiac function \[[@B39]\]. Perventricular contractions (PVCs) were noted in the human heart \[[@B40]\]. Troponin T was elevation was seen with Optison however, there were no negative histologic findings were seen \[[@B41]\]. In an other study, no changes were seen in PVCs, Troponin I, CK, CK-MB in the human heart \[[@B42]\]. In a preclinical model using the rat heart, PVCs, and microvascular leakage was noted with Optison \[[@B43],[@B44]\]. Importantly, micro lesions were seen histologically with inflammatory infiltrates 24 hours post exposure in the rat heart \[[@B44],[@B45]\]. In glass catfish model, US and USCA revealed focal damage in the tail of fish. Importantly, this was a real time assessment of the damage, which was significant \[[@B46]\]. Our results from this study are consistent with vascular damage that may contribute to the arrhythmias seen in vivo. Rat hearts were subjected to both US and Optison, and cardiac arrhythmias were induced. Cessation of US treatment reversed the effect. However, no histological effect was seen \[[@B47]\]. Rat hearts were treated with ultrasound and Optison, and the RNA was prepared for microarray analysis. The only gene up-regulated was carbonic anhydrase, so there was not dominant gene induction \[[@B48]\]. Use of ultrasound contrast agents, newly-developed microbubble-based products which are administered intravenously to enhance the ultrasound image quality, present new challenges with regard to clinical safety because of the locally destructive forces of inertial cavitation caused by the interaction of ultrasound with the micro bubbles. These destructive forces can damage the endothelium and smooth muscle of the vascular wall. The target patient population that may be exposed to microbubble/ultrasound is large and continues to grow as new applications and new products in this class are developed. For example, increased permeability due to contrast agent-induced vascular damage can capitalized upon therapeutically to deliver genes and other large molecules across endothelium. However, an adverse event that may occur from microbubble-induced vascular lesions may be the initiation or acceleration of atherosclerotic progression. Since this modality is being considered for delivery of drugs and genes, an even larger patient population (who originally had no cardiovascular disease) will be exposed to long-term risks. Therefore, it is critical to identify the ultrasound and microbubble exposure conditions which cause damage to the vascular endothelium and determine whether microbubble-induced vascular damage increases the risk of atherosclerosis in selected populations. There are several limitations in the present study: First, it was performed ex vivo under static conditions with no blood flow. Second, only one concentration of Optison was employed. In earlier studies (Miller, Dou, and Song 601--07; \[[@B6],[@B12],[@B39],[@B49]\], the microbubble concentration ranged from 0.01% to 2% and maximal RBC hemolysis was seen at 1%. In our experiment, we used 1% Optison, so we are using concentrations that are consistent with previous work. In clinical use, the recommended doses range from 0.5 to 5 ml of Optison infused in a 10 min period. For these studies, we used a 2 MHz US wave employing a four-cycle tone burst simulating a pulsed Doppler mode and having an MI of 1.9, the maximum setting available on a clinical imaging unit. It is not clear whether similar effects could occur at MI values less than 1.9. In conclusion, 2 MHz US with an MI of 1.9 and 1% Optison altered contraction and
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2579, 2199, 2684, 407, 253, 6112, 2418, 2499, 28469, 1279, 9585, 387, 9516, 32879, 15, 187, 187, 510, 1563, 310, 247, 1618, 273, 3394, 9369, 275, 253, 16916, 14564, 285, 275, 35382, 3928, 31493, 342, 253, 28593, 1621, 41668, 20816, 272, 29712, 398, 326, 403, 1959, 285, 1527, 281, 253, 1345, 27, 187, 187, 22196, 253, 28593, 1621, 41668, 20816, 272, 29712, 398, 387, 5689, 42, 323, 436, 794, 13, 27096, 285, 18366, 3114, 3652, 9759, 15, 831, 6874 ]	type of firm of course, but long-term owners of luxury brands come to mind.” The announcement seemed to give CEO Tad Smith an abundance of confidence about the company’s future: “When I said in the prior earnings call that we are going to have one or more bad quarters I think we are going to keep it to one,” he said Monday. “I feel good about things.”Doxofylline in rat brain in relation to locomotor activity. Doxofylline is a new xanthine derivative with significant bronchodilatatory activity. We have studied in HPLC the distribution of doxofylline in various areas of rat brain (cortex, cerebellum, limbic system) and its activity on the central nervous system by using a spontaneous motility test comparing it with aminophylline administered orally in equimolar doses (4.7 - 9.4 - 19 x 10(-5) mol/kg). Doxofylline is absorbed 3 or 4 times less than aminophylline at the same doses. Nevertheless, the quantity of doxofylline that goes to the brain is equivalent to that absorbed, whereas the quantity of aminophylline is about one-third. This is due to the greater liposolubility of doxofylline in comparison to aminophylline. In spite of the fact that doxofylline is easily distributed in the brain, spontaneous motility in animals is not modified, whereas aminophylline increases this activity significantly. The low affinity of doxofylline with adenosine receptors (A1 and A2) in comparison with aminophylline explains the lack of side effects on the central nervous system which has been amply documented for theophylline and for other methylxanthine derivatives.Ask HN: What podcasts do you listen to about the latest scientific discoveries? - AHappyCamper ====== nkb_ 60 seconds science [0] References: 0\. [https://www.scientificamerican.com/podcast/60-second- science...](https://www.scientificamerican.com/podcast/60-second-science/) Edit: 60 seconds science has a nugget of science news a day. It is a quick way to highlight a topic and a breakthrough in the area. When I like the info I dig further into the topic. President Jacob Zuma has signed proclamations authorising the Special Investigating Unit (SIU) to investigate certain matters in respect of the affairs of two district municipalities and a provincial department. Thick grey smog pressed against Zhao Jian's windshield, blotting visibility to two metres as he drove through China's most polluted city. Save & Share Related News "I don't remember ever seeing air pollution so bad," said Zhao of the weeks of recent haze that saw hazardous air hanging across swathes of the country. But like others in Xingtai, a 3,000-year-old city that in February was officially declared to have the country's worst air pollution, Zhao has no hope for improvement. "There's nothing you can do," he said. China's Communist leaders, currently gathered in Beijing for the annual meeting of the country's rubber-stamp parliament, the National People's Congress, have promised action on pollution in response to growing public outrage. The capital itself has seen particulate levels almost 40 times World Health Organisation (WHO) limits, and the pollution is inflicting a heavy toll on both human health and economic activity. "The state of the ecological environment affects the level of the people's well-being and also posterity and the future of our nation," Premier Wen Jiabao said in an address to the congress. "We should resolve to solve the problems of serious air, water, and soil pollution that affect the people's vital interests." Air pollution caused at least 8,572 premature deaths in four of China's biggest cities last year, and 6.8 billion yuan ($1.1 billion) in economic losses, according to a study by Peking University and Greenpeace published in December. But analysts say that without a serious threat of social unrest, China's rulers are unlikely to abandon their focus on economic growth or take radical action on polluting industries in the face of powerful vested interests. Metres away from the towering smokestacks of Xingtai's sprawling steel plants -- many of them state-owned -- shopkeepers have no difficulty pointing out the source of the pollution. Nearly half of China's emissions of PM2.5 -- tiny particles that penetrate deep into the lungs -- come from coal burning, with the rest mostly from vehicle emissions and construction. Three provinces surrounding Xingtai, 350 kilometres (220 miles) south of Beijing, burned through almost 400 million tonnes of coal last year --nearly half the total consumption of the United States. Experts agree that any meaningful action on pollution will mean cutting dependence on coal, but say Beijing's current stance will see its use rise. "We see nothing in the current policy that could meaningfully slow down the pace of coal consumption," Deutsche Bank said in a report this month. Locals said measures to reduce air pollution are unevenly enforced because of bribery. "You give the government some money and they won't do anything," Zhang said, miming the action of slipping cash into an official's pocket. While China's leaders have repeatedly stated the importance of cleaning up the pollution, responsibility for reducing emissions falls to environmental protection bureaus at the local level. Xingtai's bureau takes up a few floors of dusty, undecorated offices above a cake shop. "We're meant to implement emissions reductions policies, but we're too weak," said an official surnamed Wang, sitting opposite an ageing computer showing the day's PM2.5 reading at 179 -- seven times the WHO limit. "It's a moderate day for us," he added. China began to publish PM2.5 data for 74 cities in January, after public calls for greater transparency on the issue. State media have been unusually outspoken over the smog outbreaks. "This choking, dirty and poisonous air forces Chinese people to rethink the widespread, messy development model," said the China Youth Daily. Protests triggered by environmental issues in China have grown by almost 30 percent a year since 1996, according to the China Daily, but air pollution has not yet provoked the same level of street action as for water and land. "People are concerned about air because now they can see it," said Yang Fuqiang, a senior advisor in Beijing for the US-based Natural Resources Defense Council. "The pressure from the public is much stronger than before, but still not big enough." In his congress speech, Premier Wen restated the Communist Party's long-standing position that "development is still the key to solving all our problems". Standing on a river bank in the shadow of a huge coal-fired power station, a Xingtai estate agent who gave his surname as Wang summed up the situation. "Nearly everyone has a house and enough to eat now, so people will care about the environment more," he said.Explore Special Week Long Education Events at Travis County Parks with the Leave No Trace Traveling Trainers to Help Preserve and Protect Natural Resources for Generations to Come Leave No Trace Selected Travis County Parks as an Endangered ‘Hot Spot’ and are Hosting Events to Help Raise Awareness about Natural Areas Around the Country Facing the Threat of Irreversible Environmental Damage March 23, 2015 (Travis County, TX) The Leave No Trace Center for Outdoor Ethics and its Leave No Trace Traveling Trainers team are partnering with Travis County Parks to host community events and educational activities March 23-30th, 2015. The scenic and popular Travis County Parks have experienced visitor-created impacts in recent years including excessive trash, damage to vegetation, trees and trail erosion. Leave No Trace Traveling Trainers will focus on Hamilton Pool and Reimers’ Ranch, which are managed as sister parks due to their proximity to each other. The Hot Spot Program, a key component of the Leave No Trace in Every Park initiative, raises community awareness and brings solutions to popular natural areas facing heavy recreational use and consequently, the threat of harm to trails, parks and open space areas. The Leave No Trace Traveling Trainers travel throughout the country providing public education about how to reduce impacts in the outdoors. “The cumulative impact of so many people enjoying a great county park system such as Travis County Parks can negatively affect that place,” according to Courtney Bierschbach, Leave No Trace Traveling Trainer. “In most cases, the land impact isn’t due to a malicious intent to harm nature and wildlife. Instead, it’s simply lack of Leave No Trace education and practices.” “We are excited to work with the Leave No Trace Traveling Trainers to help educate our community and raise awareness for the future enjoyment and preservation of our beautiful landscape,” said Dan Perry Parks District Manager at Travis County Parks. During the week, Leave No Trace Traveling Trainers will provide private training sessions with County Park Staff and specific non-profit groups. On the weekend there will be a service project performed by the Texas State University Botany Club at Hamilton Pool. The following is a list of events happening in the Austin Area and in Travis County Parks with the Leave No Trace Traveling Trainers that are free and open to the public: Join the Leave No Trace Traveling Trainers at REI for this fun, informative and interactive community building presentation. This session
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1966, 30545, 1806, 753, 24035, 12143, 5464, 13, 4007, 273, 253, 43921, 266, 330, 13606, 386, 7115, 15, 187, 187, 1328, 753, 253, 1072, 310, 2032, 342, 253, 1986, 43327, 6412, 13, 247, 2022, 1282, 1850, 45455, 41879, 1981, 342, 247, 5807, 1204, 689, 1072, 14, 11523, 7875, 326, 310, 3264, 281, 1132, 562 ]	will be compiled into the assembly, and if you're using a shared bin folder, you shouldn't need to do anything more. If they won't be shared, you'll have to attach to the AssemblyResolve and TypeResolve events in the global application (more on this here). We eventually scrapped this idea because of security concerns, and ended up going with MEF data contracts but if all of your other assemblies are first party, then this should be quick and easy. Hope this helps. <%= back_link_to admin_budget_groups_path(@budget) %> <h2><%= @budget.name %></h2> <h3><%= t("admin.budget_groups.form.#{action}") %></h3> 5. Seems like every time we have worn non traditional uniforms in the past we have lost. So based on that I would say no. Although if they came out in black helmets, jerseys and pants, that would be really cool.Q: didReceiveMemoryWarning from UITableView with Images created with url data followed by app termination due to memory pressure I am setting up a UITableview, and on the side of each cell is an image that is 80x80. The TableView works perfectly when the number of cells is less than 8, but any more than this and sometimes the scroll performance can have a minor delay. With a lot more cells (around 50), the scroll performance is fine as long as you dont make a big swipe down quickly. Also, when there are a lot of cells, if you stay on this view for too long and scroll up and down, the app will receive a memory warning, and then will eventually crash. Any tips for helping to save memory? Some of these images are pretty large (5000 x 1000), or how to clear some memory when didReceiveMemoryWarning is called? I'm using ARC if that is relevant. Here is the code I use to set up the cells: - (UITableViewCell )tableView:(UITableView )tableView cellForRowAtIndexPath:(NSIndexPath )indexPath { CustomTableViewCell cell = [tableView dequeueReusableCellWithIdentifier:@"ArticleCell"]; if(cell == nil){ cell = [[CustomTableViewCell alloc] initWithStyle:UITableViewCellStyleSubtitle reuseIdentifier:@"ArticleCell"]; } cell.titleLabel.text = nil; cell.imageRight.image = nil; Article article = [self.articles objectAtIndex:indexPath.row]; [cell.titleLabel setText:article.title]; if(!article.pictureData){ dispatch_async(dispatch_get_global_queue(DISPATCH_QUEUE_PRIORITY_DEFAULT,0), ^{ NSData data = [NSData dataWithContentsOfURL:[NSURL URLWithString:article.image]]; dispatch_sync(dispatch_get_main_queue(), ^{ article.pictureData = data; UIImage img = [[UIImage alloc] initWithData:data]; CGSize imgSize = CGSizeMake(80, 80); img = [img resizeImage:img newSize:imgSize]; [cell.imageRight setImage:img]; [self.tableView beginUpdates]; [self.tableView reloadRowsAtIndexPaths:[NSArray arrayWithObjects:indexPath, nil] withRowAnimation:UITableViewRowAnimationNone]; [self.tableView endUpdates]; }); }); } else [cell.imageRight setImage:[UIImage imageWithData:article.pictureData]]; return cell; } The point is though that this tableView is loading all of the cells perfectly, and it can make it all the way through even 50+ rows. I just need to clear some memory, I'm just unsure how. A: Your cells are set up differently depending on whether the pictureData is available: If pictureData is not yet available, it will be downloaded & its full resolution data set on the article object; afterwards a smaller thumbnail image is generated and set on cell.imageRight. However, if the picture has already been downloaded, a full resolution image is created from pictureData and set on the cell's imageRight without resizing it first.. } else [cell.imageRight setImage:[UIImage imageWithData:article.pictureData]]; This means that as soon as all pictures have been loaded, each time the tableView dequeues a reusable cell it will also set the full res image on cell.imageRight. I suppose this explains the memory issues you are encountering. My advice would be to add a UIImage thumbnail property to the articles object, cache the resized image there after it has been generated from the downloaded data and always use this -thumbnail for the cell's imageRight. Additionally, this will reduce the nontrivial system load (both on memory & cpu) caused by re-generating and resizing the images every time the tableView updates a cell. Another thing: there's actually no need to bother the main thread with the image resize operation, I suspect that's where the hitching comes from when scrolling. It should help to leave that on the global queue and dispatch_async only the table update to the main queue afterwards. U.S. church attendance is dropping, but Hope Church in Memphis, Tennessee, is packing the pews — or, in Hope’s case, modern theater seats with individual cup holders. The Evangelical Presbyterian Church affiliate, one of the fastest-growing in the nation, holds four services each weekend to accommodate the nearly 7,000 parishioners who come for the multiethnic community, the coffee kiosks, the mix of contemporary and traditional music, the outreach to non-churchgoers, and the biblically based message. Hope’s conservative stance on human sexuality — faithfulness in marriage, chastity in singleness, and marriage between one man and one woman — has done little, if anything, to rein in the church’s galloping growth. “I think what people appreciate, honestly, is do you believe what you say you believe?” said Hope senior pastor Rufus Smith. “If you’re going to be an [LGBTQ] affirming church, be that, and if you’re not, be that, so people will appreciate whatever your position of conscience is. And I think that is what has helped [evangelical] churches not experience a decline because of that particular issue.” Four years after the Supreme Court legalized same-sex marriage, conservative churches, led by the evangelicals and nondenominationals, still draw enthusiastic crowds each weekend to their megachurches, even as liberal mainline Protestant denominations wilt. “For evangelicals, being conservative is what has held them to that same level as a share of the population,” said Ryan P. Burge, an assistant professor of political science at Eastern Illinois University who tracks the data. Yet the future is uncertain as attendance plateaus. Evangelicals made up 22.5% of the U.S. population in 2018, and that share is expected to inch up to only 22.6% by 2030, according to Mr. Burge’s numbers, which are based on the General Social Survey, a trove of sociological data. A 2016 study led by Wilfrid Laurier University professor David Millard Haskell found that the “recipe for church growth” was conservative theology coupled with worship music featuring drums and guitars, but he said he thinks the growth has hit a wall since then. He also said cultural upheaval of gender issues and the battles it entails — such as same-sex wedding cakes, public accommodations and transgender athletes — is taking a toll. “What’s going on in the culture with the greater acceptance of gay marriage will make it harder for churches promoting traditional views,” Mr. Haskell said. But he added: “If a church stuck with their traditional views and were able to articulate it in a way that met the hearts and minds, the best research shows that keeping to those traditional values will cause your church to grow.” Religious conservative leaders at the national level see the fight over gender issues as make-or-break. “The current cultural attack is indeed about our right to live according to our faith and even about what it means to be a man or a woman,” said Mario Diaz, general counsel of Concerned Women for America. “That is why we are engaged there most prominently. When males are entering women’s private spaces and demanding to compete against them in sports, we must speak up.” ‘Culture war is dead’ Blaming same-sex marriage for the decline of Christian churchgoers in America would be too simplistic, religious scholars say, given that the slide can be traced to the turn of the century — the 19th century — and picked up steam during the sexual revolution of the 1960s. Mainline denominations that flowed with societal changes, such as the Episcopal Church, the Presbyterian Church (USA), the Evangelical Lutheran Church in America, and the United Church of Christ “have all seen dramatic declines in their membership and attendance as they liberalize their teachings on human sexuality,” said Keith Boyette, president of the Wesleyan Covenant Association. He said the same is true with the United Methodist Church, a mainline denomination grappling with a schism over same-sex marriage that is expected to play out
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11345, 17187, 27, 4278, 15, 17187, 187, 50274, 373, 454, 68, 40427, 27, 4278, 15, 15024, 15, 15024, 2548, 187, 50274, 14966, 301, 27, 4278, 15, 15024, 15, 14966, 21691, 15, 14966, 2618, 187, 50274, 6839, 1377, 40427, 27, 4278, 15, 15024, 15, 14966, 21691, 15, 14966, 2548, 187, 50274, 20476, 2606, 27, 4278, 15, 15024, 15, 14966, 21691, 15, 20476, 4769, 187, 50274, 16726, 14729, 1596, 27, 4278, 15, 15024, 15, 14966, 21691, 15, 16726, 11257, 23912, 15, 1596, 187, 50274, 16726, 14729, 301, 27, 4278, 15, 15024, 15, 14966, 21691, 15, 16726, 11257, 23912, 15, 301, 187, 50274, 3024, 27, 4278, 15 ]	gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Behavior:EC2/NetworkPortUnusual: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId sourceipaddress: details.finding.action.networkConnectionAction.localIpDetails.ipAddressV4 destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Behavior:EC2/TrafficVolumeUnusual: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId sourceipaddress: details.finding.action.networkConnectionAction.localIpDetails.ipAddressV4 destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Trojan:EC2/BlackholeTraffic: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Trojan:EC2/DropPoint: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.
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App. at 24. When it was disclosed in response to a March 3, 1982, oral inquiry that it would take DOJ several months to reach a decision, PLEI filed, on April 30, 1982, an FOIA complaint in the District Court. 3 On July 19, 1982, DOJ filed a motion for summary judgment. Accompanying the motion was the declaration of the Chief of the Freedom of Information Act and Privacy Act Unit within OLP. The declaration (1) released all but three and one-half lines of one of the documents, (2) described the remaining documents, and (3) claimed section 552(b)(2) and (b)(5) exemptions for the undisclosed material. App. at 31-40. On July 29, 1982, PLEI moved for leave to amend its complaint to include documents sought in a separate, later FOIA request, and on August 16, 1982, PLEI filed a motion for summary judgment. 4 On August 17 and 18, 1982, a hearing was held in San Diego in the criminal case United States v. Sasway, Crim. No. 82-0504 (S.D.Cal.1982). See PLEI, supra, 556 F.Supp. at 447. In that hearing, DOJ, in order to refute a defense claim of selective prosecution, publicly disclosed its guidelines for prosecuting Selective Service non-registrants. Id. Those guidelines and the cover letter transmitting the guidelines to United States Attorneys were two of the four documents sought by PLEI. On or about September 3, 1982, after the guidelines became public in Sasway, they and the cover letter were released to PLEI. Id. 5 DOJ continued to defend its position with regard to the withholding of the two remaining documents. On September 21, 1982, the District Court issued an order refusing leave to PLEI to amend its complaint and granting summary judgment for DOJ with regard to the two undisclosed documents, sustaining the claim of exemption under 5 U.S.C. Sec. 552(b)(5). App. at 59-60. 6 Subsequently, PLEI moved for an award of attorney's fees and litigation expenses, pursuant to 5 U.S.C. Sec. 552(a)(4)(E). The District Court denied PLEI's motion, holding that PLEI had not substantially prevailed in the FOIA action, as required under section 552(a)(4)(E), because no causal nexus had been shown between PLEI's action and the release of the two documents PLEI received. Alternatively, the District Court held that even if PLEI had substantially prevailed and was eligible for attorney's fees, an analysis of the factors enumerated in Cox v. United States Department of Justice, 601 F.2d 1, 7 (D.C.Cir.1979), for entitlement to such fees, showed that PLEI was not so entitled. II 7 An award of attorney's fees and litigation costs incurred in pressing an FOIA claim may be made only if the complainant has substantially prevailed. 5 U.S.C. Sec. 552(a)(4)(E). While it is clear that a court order compelling disclosure is not a prerequisite for an award,1 it is also clear that more than post hoc, ergo propter hoc must be shown.2 An FOIA litigant seeking attorney's fees must show that "prosecution of the action could reasonably be regarded as necessary to obtain the information ... and that a causal nexus exists between that action and the agency's surrender of the information ...." Cox v. United States Department of Justice, supra, 601 F.2d at 6 (citations omitted); see also Sweatt v. United States Navy, supra, 683 F.2d at 423-24; Church of Scientology v. Harris, supra, 653 F.2d at 588. 8 To be sure, the Justice Department's release of the two documents at issue in the attorney's fees motion did occur after the filing of an FOIA complaint. However, the initial release of the documents occurred in an unrelated criminal case. Only then did DOJ release the documents to PLEI, specifically representing to the District Court that "[i]n view of the public disclosure of the guidelines, [DOJ] will discontinue its efforts to withhold these materials." Filing of September 3, 1982, App. at 44. The Justice Department released only those documents which had already been publicly disclosed; it did not release the other documents that were the subject of PLEI's FOIA action. The District Court thus concluded that PLEI failed to show a causal nexus between its FOIA action and DOJ's release of the documents. 9 Our review of the District Court's conclusion that PLEI did not substantially prevail in the litigation, so as to be eligible for attorney's fees, is narrow in scope. The findings of fact underlying a conclusion as to whether an FOIA litigant has substantially prevailed are reviewed under a clearly-erroneous standard. See Sweatt v. United States Navy, supra, 683 F.2d at 425; Crooker v. United States Department of the Treasury, supra, 663 F.2d at 142. In this case, there is no dispute as to the findings of fact. Thus, the District Court's findings of fact are manifestly not clearly erroneous. 10 Nor is there any indication that in reaching its conclusion the District Court applied an improper legal standard to those findings of fact.3 PLEI would have us find legal error by interpreting the causal nexus requirement in significantly weakened form. PLEI argues that an FOIA plaintiff need not show that its suit was a direct cause of the release of the documents sought. Appellant's Brief at 28. However, the cases cited for this proposition fail to support it. In each case, the release of the documents was directly attributable to the plaintiff's FOIA action.4 Alternatively, PLEI invites us to infer causality from the timing of the release of the documents. Appellant's Brief at 32-33. Such an inference, however, would be contrary to the law of this Circuit.5 11 There is no indication in the record or in the District Court's findings of fact that would indicate that the PLEI action influenced the DOJ decision to release the documents in Sasway. Nor is there any indication that DOJ simply abandoned its defenses to PLEI's claim. The District Court appears to have understood, and to have correctly applied, the causal nexus requirement. Accordingly, we must accept the District Court's finding that PLEI was not eligible for an award of attorney's fees. 12 Only movants who have prevailed substantially, and are therefore eligible, may be found entitled to an award of attorney's fees and litigation expenses under section 552(a)(4)(E). See Fund for Constitutional Government v. National Archives & Records Service, supra, 656 F.2d at 870; Church of Scientology v. Harris, supra, 653 F.2d at 587; Nationwide Building Maintenance, Inc. v. Sampson, supra, 559 F.2d at 709. Since PLEI is not eligible for an award of attorney's fees and litigation expenses, we have no occasion to comment on the factors that would bear on PLEI's entitlement.6 13 For the foregoing reasons, the judgment of the District Court is 14 Affirmed. * Sitting by designation pursuant to 28 U.S.C. Sec. 294(d) 1 Sweatt v. United States Navy, 683 F.2d 420, 423 (D.C.Cir.1982); Fund for Constitutional Government v. National Archives & Records Service, 656 F.2d 856, 871 (D.C.Cir.1981); Church of Scientology v. Harris, 653 F.2d 584, 587 (D.C.Cir.1981); Crooker v. United States Department of the Treasury, 663 F.2d 140, 141 (D.C.Cir.1980); Cox v. United States Department of Justice, 601 F.2d 1, 6 (D.C.Cir.1979); Nationwide Building Maintenance, Inc. v. Sampson, 559 F.2d 704, 708 (D.C.Cir.1977); Cuneo v. Rumsfeld, 553 F.2d 1360, 1364 (D.C.Cir.1977) 2 Sweatt v. United States Navy, supra, 683 F.2d at 423; Church of Scientology v. Harris, supra, 653 F.2d at 587-88; Cox v. United States Department of Justice, supra, 601 F.2d at 6 3 See generally United States v. Singer Manufacturing Co., 374 U.S. 174, 194 n. 9, 83 S.Ct. 1773, 1784 n. 9, 10 L.Ed.2d 823 (1963); Federal Trade Commission v. Texaco, Inc., 555 F.2d 862, 876 n. 29 (D.C.Cir.), cert. denied sub nom. Standard Oil Co. v. Federal Trade Commission, 431 U.S. 974, 97 S.Ct. 2939,
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19, 15, 29036, 634, 9215, 4871, 313, 3529, 368, 1849, 4272, 407, 374, 10, 281, 253, 18400, 547, 896, 13, 7005, 2835, 253, 22595, 1581, 1972, 15, 1310, 368, 1472, 1561, 36444, 3, 313, 23, 2188, 582, 368, 1833, 320, 4030, 15, 1310, 417, 13, 368, 1833, 971, 281, 3451, 323, 9215, 4871, 15, 3166, 436, 1078, 35827, 323, 9215, 14679, 15, 24440, 247, 11593, 29609, 13, 7529, 281, 253, 18106, 13, 949, 253, 9215, 1127, 15, 28396, 387, 4055, 896, 13, 2557, 2112, 436, 1386, 281, 634, 2303, 9215, 4871, 15, 10338, 247, 1616, 327, 253, 1386, 15, 10209, 13, 3812, 247, 9118, 1386, 949, 634, 1616, 13, 7562, 352, 20277, 281, 253, 18106, 1282, 281, 1616, 253, 14200, 390, 39937, 9215, 15, 187, 187, 20, 15, 28396, 387, 253, 18106, 387, 4055, 896, 13, 1616, 835, 634, 9215, 14, 3433, 1714, 2557, 25808, 253, 9118, 1386, 15, 831, 310, 634, 747, 9215, 1127, 15, 5838, 849, 2080, 1840, 390, 2708, 253, 3236, 9215, 1127, 436, 310, 13, 347, 368, 588, 878, 281, 4575, 253, 4430, 13928, 436, 1072, 2408, 15, 24440, 634, 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253, 896, 13, 285, 672, 11575, 432, 253, 1930, 13, 253, 13574, 403, 3579, 432, 253, 7623, 285, 253, 896, 310, 625, 11906, 685, 253, 2914, 15, 187, 187 ]	below the armpit. Spread or overlap the line evenly to achieve the correct back length. 3. Redraw lines if needed by blending the pattern lines at the overlap or spread. For preliminary front adjustments, you need to lengthen or shorten the front bodice the same amount as you did the back bodice. ## BUST ADJUSTMENTS All standard bodice patterns are made for a B-cup bra size. If you are smaller or larger than a B cup, and/or your bust sits higher or lower than average, then you'll want to adjust your pattern before you start to get a better fit. 1. With the elastic still around your waist, look in a mirror and measure vertically from your shoulder, over the fullest part of your bust, and down to your waist. The bodice front needs to be this long to fit properly. Also note the measurement along that line, where the apex of your bust (or bust point, basically your nipple) sits. You'll need this to mark an accurate bust point on your pattern. 2. Measure from side seam to side seam, across the fullest part of your bust. Add 1" (2.5cm) for wearing ease. Divide in half (because the pattern is half of the front). Also note the distance from the side seam to the bust point. 3. On the front bodice pattern, locate the pattern's bust point by drawing straight lines through the center of each dart. Where they intersect is the pattern's bust point. Mark the bust point on the pattern and mark the dotted lines as pictured. Cut along each of these lines, leaving only a small hinge at the armhole and, for the large bust adjustment, also at the bust point to pivot the pieces. For a small bust adjustment cut through the bust point. 4. Working on a flat surface, spread or overlap the pattern pieces as shown until the length and width measurements you took earlier are achieved. Keep the waistline of the bodice even and the center-front line even. A general rule will be to increase/decrease length and width about ½" (13mm) per change in cup size. For instance, a D cup will add about 1" (2.5cm) in length and width. Tape the altered pattern in place. 5. Mark the correct bust point on the pattern as you measured on yourself earlier, both the height (as measured from your shoulder) and the width (as measured from the side seam). Mark new waist and bust dart points as follows: The point of the waist dart will be 1" (2.5cm) directly below your new bust point. The side dart point will be 1" (2.5cm) away from your bust point, in the direction of the dart (to the side and slightly down). Connect these new points to the end of the legs of the original darts, which have now spread (for larger cups) or overlapped (for smaller cups). Redraw pattern lines smoothing out any bumps or jags caused by the alteration. 6. If the bust point is higher than its original position, redraw the darts to point toward the higher point. In cases where the corrected bust point is lower than the side dart end points, the side dart end points will also have to be lowered. Measure the distance that the bust point was lowered. Lower the end points of the dart legs the same distance, taking care to lower them vertically. In other words, move the entire side dart downward, not just the tip, on the spread-out or overlapped pattern. This keeps the width of the front bodice consistent. Draw in the new dart legs, lowering the tip of the waist dart the same amount the bust dart was lowered on the spread or overlapped pattern. 7. To complete the pattern, redraw the side seam by connecting the new dart legs with the armhole and the waistline for the spread or overlapped pattern. ## NECK ADJUSTMENTS If the neckline is too tight or too loose, adjust the pattern accordingly. 1. Measure around your neck where you'd like the finished neckline to sit. Divide the measurement in half as you are working with half the pattern. 2. Mark the stitching lines for the neck and shoulder on both the front and back bodice, ⅝" (1.5cm) in from the cutting edge. Line up the shoulder stitching lines and tape in place. Don't worry about the shoulder dart. Measure the stitching line for the neck by holding a soft, flexible tape measure on its side (that is, standing up on its thin edge), not flat, around the neck stitching line. Hold it so the increments are against the pattern for the most accurate measure. 3. For every 1" (2.5cm) difference between the stitching line and the target measure, move the pattern's neckline ¼" (6mm) at the center front and at the shoulder line, either in, toward the neck to make it smaller, or out, away from the neck to make it bigger. For example, if you want to increase the neck 1" (2.5cm), you'll move the center-front point down ¼" (6mm) and the shoulder line out ¼" (6mm). Keep the center back the same. Redraw the neck stitching line, and double-check the pattern measure. Add the ⅝" (1.5cm) seam allowance to the stitching line. Adjust again if needed. ## SHOULDER ADJUSTMENTS ### SHOULDER SLOPE CORRECTION This method will correct for wide or narrow shoulders, as well as square or sloping shoulders. 1. Have a friend measure across your back, from shoulder point to shoulder point, where sleeve seams would sit. This is your shoulder width. Divide this by 2, since the pattern is for half of the back. Then, with the elastic around your waist, have a friend measure from your waist at center back, to your shoulder point, where a sleeve seam would sit. This is the shoulder slope. 2. Compare your shoulder width (that you've divided by 2) to the bodice back, omitting the seam allowances. If you're within ¼" (6mm), you'll be fine. If not, you'll want to correct for shoulder width. Do this before correcting for shoulder slope. Draw a horizontal guideline, parallel to the waist, through the shoulder point. Starting at center back, measure along this line to your target shoulder width. Make a mark on the line. Next, draw a vertical line through your mark, keeping it perpendicular to the waistline to mark the wider or narrower shoulder. 3. Starting at the waist at center back, mark where your shoulder-slope measure crosses the vertical line. This is your new shoulder point. Note how far above or below the original shoulder point this is, as you will need to adjust the armhole this same amount. Draw your new shoulder line from this point to the neck. 4. Find the midpoint of your new shoulder line. This will be the center of your shoulder dart. At the midpoint, draw a line perpendicular to your shoulder line that is the same length as the original dart. This is your dart center, and the end is your dart point. Measure the width of the original dart. Mark the dart width on the shoulder line with the perpendicular line in the center. Draw in your dart legs, connecting these marks to the end of the perpendicular line. 5. Correct the armhole as needed: If your shoulder width was adjusted, but not the shoulder slope, redraw your armhole, starting at the shoulder, and blend back into the existing armhole about midway down the curve for the wider or narrower shoulder. If your shoulder slope was also changed, draw a vertical guideline at the outer point of the armhole/side seam, perpendicular to the waist. Mark a new point along this guideline up or down—the same amount that you raised or lowered the shoulder point. This keeps the armhole the same size. To redraw this line, try to mimic the bottom of the curve through the midpoint of the curve. Then blend to your new shoulder point for a wider or narrower shoulder. 6. Apply the same changes to the front bodice: Draw a horizontal guideline through the front bodice shoulder point. Move the shoulder point in or out the same amount that you moved the back shoulder. Draw a vertical line through this new point. Now raise or lower the shoulder point the same amount that you raised or lowered it in the back, to correct for shoulder slope. Connect this mark to the original neckline. Redraw the armhole as in step 5. 7. When you change the armhole on the bodice, you then must change the armhole on the sleeve so it still fits into the bodice. For shoulder width adjustments, you may or may not need to adjust the armhole, depending on the changes. Measure the original armhole stitching lines on the back bodice. Now measure your new armhole on your back bodice, along the stitching lines. The difference between the two measurements is the amount that you will raise or lower the sleeve cap. If your new armhole is bigger than the original armhole, you will raise the sleeve cap by that same amount. If your new armhole is smaller than the original armhole, you will lower the sleeve cap by that amount. ### ROUNDED SHOULDERS For figures with rounded shoulders, there are often gaping armholes in the back, and when viewed from the side, the shoulders are forward from the neck and the back is more prominent than the front.
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16892, 7101, 407, 253, 734, 664, 3292, 273, 1027, 26752, 30585, 15, 2053, 39570, 875, 5112, 45086, 285, 5685, 11727, 13, 2168, 9919, 275, 3060, 407, 6089, 961, 285, 10916, 79, 678, 13, 45253, 1919, 2190, 731, 597, 29843, 4948, 273, 1869, 273, 1027, 20801, 13, 275, 247, 5431, 2448, 13, 811, 25736, 1566, 15, 187, 187, 36048, 13, 690, 3910, 858, 3464, 13, 2330, 342, 253, 1027, 30460, 326, 253, 1307, 346, 32525, 3, 9288, 275, 253, 767, 22349, 15, 2726, 253, 42471, 45086, 352, 14667, 247, 2590, 22555, 2192, 1788, 13, 533, 275, 6181, 346, 32525, 3, 20845, 281, 3890, 247, 2442, 273, 4495, 326, 13, 604, 417, 10214, 281, 11727, 13, 369, 5604, 417, 7094, 10891, 888, 342, 352, 15, 3690, 543, 579, 290, 342, 253, 5899, 4495, 273, 346, 3088, 36149, 3, 313, 35861, 281, 253, 897, 44190, 432, 253, 5685, 1307, 795, 4015, 73, 250, 64, 12062, 253, 5112, 2715, 273, 795, 394, 860, 23297, 64, 8424, 1314, 13730, 432, 253, 2440, 273, 253, 1966, 23496, 285, 13730, 432, 253, 48641, 29254, 273, 25680, 13, 347, 3715, 40699, 407, 1219, 394, 1316, 254, 13, 949, 253, 10732, 273, 346, 783, 33977, 3946, 449, 831, 4495, 13, 11797, 407, 271, 7445, 273, 8249, 414, 326, 310, 417, 5742, 10527, 275, 10541, 13, 12103, 14731, 275, 253, 32870, 273, 20365, 3397, 313, 52, 10064, 459, 582, 21698, 1497, 313, 45, 860, 6584, 14, 35562, 1316, 582, 30543, 12792, 313, 45, 317, 266, 582, 285, 17541, 2175, 313, 35, 435, 1041, 582, 275, 1386, 342, 253, 8870, 382, 5248, 273, 2892, 273, 5859, 313, 45, 886, 950, 481, 20, 3308, 13, 1223, 4619, 3762, 275, 42471, 7106, 327, 253, 346, 26717, 414, 3, 15903, 432, 247, 22555, 6907, 13, 275, 7785, 253, 4073, 369, 4845, 327, 247, 10732, 273, 346, 32525, 3, 342, 271, 20711, 248, 33977, 25661, 15, 187, 187, 688, 271, 3929, 7429, 346, 4045, 272, 15977, 937, 7949, 87, 10133, 23519, 47761, 13, 4931, 253, 954, 1774, 37190, 273, 5112, 3762, 275, 3968, 13, 8219, 326, 697, 19532, 18177, 8696, 10534, 275, 697, 3480, 273, 10527, 13260, 275, 3718, 273, 247, 3946, 273, 4028, 326, 41469, 281, 39589, 697, 1211, 4803, 15, 16513, 795, 44, 13825, 1962, 380, 23297, 64, 1157, 534, 369, 18107, 407, 10799, 34587, 989, 18702, 13, 5112, 3762, 574, 347, 271, 5667, 8847, 326, 352, 369, 417, 346, 936, 320, 1633, 3, 533, 346, 936, 2489, 3253, 352, 310, 7032, 273, 449, 21, 4325, 436, 1127, 273, 1859, 13, 275, 8063, 13, 352, 1045, 14735, 667, 6474, 5426, 13, 3192, 327, 253, 4495, 1677, 281, 352, 432, 581, 673, 281, 253, 1735, 15, 831, 11424, 697, 12046, 273, 41859, 1014, 22293, 22766, 10527, 838, 1135, 3450, 84, 285, 24705, 11390, 13, 824, 347, 1110, 8671, 407, 399, 1000, 4355, 13, 401, 276, 68, 1923, 13, 1605, 282, 86, 2721, 13, 378, 5353, 83, 41936, 13, 285, 12829, 302, 472, 13, 281, 1416, 760, 253, 2201, 3773, 15, 1198, 436, 1921, 13, 275, 271, 4572, 346, 2374, 15977, 3, 1108, 347, 973, 347, 275, 253, 2312, 344, 3534, 387, 253, 19213, 8059, 387, 34676, 27353, 2499, 326, 8069, 23942, 321, 456, 253, 2448, 2180, 273, 5112, 3762, 1108, 40738, 17486, 1041, 16402, 253, 38291, 346, 565, 16147, 1483, 3, 20808, 273, 3762, 15, 733, 556, 642, 643, 1789, 685, 3139, 13, 275, 512, 1896, 9508, 13, 1690, 326, 273, 697, 1211, 2297, 318, 13, 281, 253, 1127, 326, 1014, 253, 20711, 248, 33977, 15903, 6185, 14280, 281, 2489, 247, 19098, 1561, 253, 1077, 3762, 352, 13698, 281, 1275, 1137, 15, 22, 187, 187, 2042, 253, 14238, 273, 5112, 3762, 452, 644, 2918, 5506, 323, 1097, 6489, 285, 3064, 8672, 275, 2448, 1345, 25200, 13, 9441, 804, 247, 1798, 3569, 4736, 432, 253, 2710, 372, 17439, 422, 8333, 310, 2834, 285, 8489, 10341, 15, 1737, 597, 4388, 281, 5691, 327, 247, 21543, 311, 19424, 6415, 310, 253, 830, 273, 6779, 1108, 7192, 347, 253, 2256, 434, 6576, 323, 10938, 6612, 15, 380, 1921, 2139, 253, 2605, 273, 1415, 318, 3249, 762, 2983, 13, 275, 512, 697, 1896, 10006, 13, 310, 326, 352, 310, 24473, 7898, 13, 285, 3103, 43337, 512, 643, 1896, 30460, 15, 16823, 1700, 281, 352, 310, 253, 3426, 43416, 1430, 273, 13894, 1972, 13, 534, 403, 29403, 275, 824, 247, 1039, 347, 281, 9238, 907, 1016, 643, 15, 3308, 13, 323, 1650, 13, 378, 5353, 83, 41936, 434, 4154, 327, 253, 19945, 875, 897, 1318, 285, 6431, 1318, 11029, 281, 45688, 24846, 347, 973, 347, 281, 11399, 19381, 1204, 1108, 533, 671, 13, 387, 253, 1072, 673, 13, 281, 10418, 581, 285, 253, 643 ]	ndigung: Ein Geistergespräch zwischen Lyotard und Habermas_ (Frankfurt: Suhrkamp, 1988). 11 Albrecht Wellmer, "On the Dialectic of Modernism and Postmodernism," trans. D. Roberts, _Praxis International_ , 5.5 (1985): 337–62. 12 Axel Honneth, _Critique of Power: Reflective Stages in a Critical Social Theory_ , trans. K. Baynes (Cambridge, MA: MIT Press), 1993. 13 See J. Habermas, _The Philosophical Discourse of Modernity: Twelve Lectures_ , trans. F. G. Lawrence (Cambridge, MA: MIT Press, 1998), here pp. 83–105. 14 See J.-F. Lyotard, _Des dispositifs pulsionnels_ (Paris: Bourgois, 1973), p. 118. [Translator's note: The chapter on "Adorno as the Devil" is available in English in Robert Hurley's translation in _Telos_ , 19 (1974): 128–37.] 15 Lyotard, _The Postmodern Explained to Children_ , p. 78. 16 The relationship between Adorno and Lyotard is analyzed in all its twists and turns by M. Cohen-Halimi, _Stridence spéculative: Adorno, Lyotard, Derrida_ (Paris: Payot, 2014), through oblique reference to Derrida. At the Cerisy-La-Salle conference – whose proceedings were later collected in the volume _Les Fins de l'homme: À partir du travail de Jacques Derrida_ (Paris: Galilée, 1981) – Lyotard asked Derrida to speak about his relationship with Adorno. The answer came only several years later, in 2001, when Derrida received the Adorno prize and gave a speech later published in _Fichus_ (Paris: Galilée, 2002) in which he accorded Adorno _le mérite indéniable_ of having reopened the question on the meaning of the phrase "after Auschwitz." 17 J.-F. Lyotard, _Discours, Figures_ , trans. A. Hudek and M. Lydon (with introduction by J. Mowitt; (Minneapolis: University of Minnesota Press, 2011 [1971]). 18 As Alain Badiou expresses it in "Custos, quid noctis?" [1983], in idem, _The Adventure of French Philosophy_ , 223–39, here p. 231. 19 See especially J.-F. Lyotard, _The Differend: Phrases in Dispute_ , trans. G. van den Abbeele (Minneapolis: University of Minnesota Press, 1988). 20 Lyotard, _The Postmodern Explained to Children_ , pp. 15–16. 21 Ibid., p. 16. 22 J.-F. Lyotard, _Heidegger and "the Jews,"_ trans. A. Michel and M. Roberts (with foreword by D. Carroll; Minneapolis: University of Minnesota Press, 1990), p. 84. 23 J.-F. Lyotard, _Enthusiasm_ , trans. G. van den Abbeele (Stanford, CA: Stanford University Press, 2009 [1986]), p. 58. # Part III French Theory # 7 Difference and History Perhaps no definition of French theory hits the mark better than Baudrillard's, according to which "it exists only when our eyes are closed."1 Like a fantasy imprinted in the mind but lacking any correspondence in reality, it is only recognizable by its effects – which radiated out from American campuses onto the global cultural stage over the span of a few years. As François Cusset observes in the most convincing reconstruction of the affair, it involved something different from and bigger than what other waves of cultural importation had brought from France to America. While surrealism, existentialism, and "Annales" historiography were transplanted in their native form before being Americanized, French theory was a product created from scratch by American intellectuals after a small squad of French philosophers arrived in the United States. Cogently defined as "an American interpretation of French readings of German philosophers,"2 it appears to be the result of a dual decontextualization – of German philosophical culture, as operated by the French, and of French philosophical culture, as operated by the Americans. The same liberty that Derrida, Deleuze, and Foucault took in reworking texts by Hegel, Nietzsche, and Heidegger was practiced by American interpreters on French authors. As had already happened the first time round, the effect of this second contamination was twofold. Although it is true that the French texts lost something of their original character by being first denationalized and then reterritorialized, once they came into contact with the new context they acquired a new-found energy, which projected them into the international circuit, in English translation. Certainly a French book arriving in Tokyo or Sydney through American mediation is no longer the same as it was. But, instead of diminishing its impact, this ended up boosting its force, as more meanings came to be layered on top of the original ones. Without retracing the ambivalent effects of French theory on American culture, which have been thoroughly examined by Cusset, I will stick to the relationship with German philosophy, transplanted in America by intellectuals who fled Nazi Germany. The general turnover in hegemony witnessed by the marginalization of Marcuse's thought was followed by a hybridization that blurred the European contrasts. What in Europe had taken on the features of a genuine _Kulturkampf_ in America became a composite of heterogeneous elements. American authors such as Nancy Fraser, Seyla Benhabib, and Martin Jay introduced Frankfurt School theories into the American context, while others, such as Silvère Lotringer, Judith Butler, and Gayatri Spivak circulated theories from France in a horizon marked by the interweaving of different lexicons. These grafts between French thinkers and German philosophy, already attempted in Europe by Wellmer and Honneth, intensified until among them they fused forms of thought of different origins, in a typically American, transnational model. Nevertheless, some differences did remain, associated with the different meanings that the term "theory" acquired in the two contexts. With the Frankfurt thinkers it retained a clear philosophical inflection, but in France "theory" tended to express a potential of meaning that, if not contrary to philosophy, was certainly not entirely coincident with it. Incongruent with the traditional meaning of "doctrine" (according to the use deriving from the German term _Lehre_ ), the French version of _théorie_ stemmed partly from the development of the human sciences and partly from the Marxist critique of ideology, as developed chiefly by Althusser, through the notion of "theoretical practice." This meaning, inspired by an ideal of scientificity that is not specifically theoretical in tone, gained currency in the disciplines of linguistics (Saussure), anthropology (Lévi-Strauss), psychoanalysis (Lacan), and literary studies (Barthes), in line with the rationalist cast of history of science (Lecourt).3 Thus, while critical theory in Frankfurt focused on the "criticality" pole from a philosophical angle, in Paris the stress was placed on a notion of "theory" with an antitheoretical leaning. In an article entitled "Doing Theory," Silvère Lotringer, perhaps the most important mediator of French theory in America, argues that its peculiar trait lies precisely in its lack of theoretical assumptions in favor of a practice of writing that prefers to dictate its own rules. Unlike _Kritische Theorie_ , which was guided by precise doctrinal premises, French theory had as an essential characteristic that it was not "to be something" but "to become everything it is capable of."4 From this point of view, in principle, it eludes any stable definition, taking on the meaning given to it from one time to the next. This explains its attitude of embracing even markedly heterogeneous theoretical presuppositions and semantic vectors, such as those adopted by Derrida, Foucault, Deleuze, Baudrillard, and Lyotard, to name only the major players. For this reason, in an interview "On Theory" – as well as in the talk he gave at the 1966 conference at Johns Hopkins University that effectively inaugurated the American period of French theory – Roland Barthes asserted the structurally "intransitive" pursuit of theory. It has no other object than itself, in all possible versions, including that of its own negation, to the point that even the antitheoretical polemic tends to become a genre within the very theory it aims to refute.5 If the protocols of French theory have been held responsible for both identity and difference politics in American public discourse, inferring a particular political goal from the various deconstructive practices is difficult and somewhat arbitrary. What they aim to challenge on a metapolitical plane is the form of representation – understood as the subject's apparatus for controlling reality. The reason why the structure of signification comes under attack, in all its possible modes, is that it is inevitably partial, and therefore excludes all other possible meanings. Opposed to it is the complete commutability of utterances, which are conveyed in such a way as to neutralize each other. Thus, for example, Baudrillard's argument on the equivalence between use value and exchange value serves to criticize capitalism as well as to overcome Marxism – but also, at the same time, to affirm one and the other
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5383, 8613, 14, 20359, 25136, 313, 47, 1830, 50, 10, 4302, 575, 683, 47, 1830, 50, 1092, 1146, 2104, 281, 8067, 366, 1355, 6318, 12672, 5085, 313, 50, 7575, 323, 2159, 10, 12319, 432, 370, 740, 5, 281, 2761, 370, 2313, 5, 42414, 15, 18770, 3434, 310, 1146, 9940, 281, 2007, 2572, 253, 1180, 273, 42414, 326, 1165, 7575, 84, 476, 8722, 13, 533, 347, 253, 1180, 273, 42414, 17202, 13, 253, 5691, 273, 15974, 1016, 38294, 15978, 285, 41435, 731, 432, 25824, 6355, 285, 47188, 11724, 9086, 4916, 440, 48200, 494, 575, 683, 6148, 35782, 3620, 770, 27, 9960, 3942, 1570, 1916, 4311, 598, 4457, 436, 1127, 13, 8607, 403, 36636, 5939, 6318, 35615, 575 ]	public final boolean isBigDecimalShape() { return getType() == ShapeType.BIG_DECIMAL; } /** * @return Returns true if the shape is a {@link BigIntegerShape} shape. / public final boolean isBigIntegerShape() { return getType() == ShapeType.BIG_INTEGER; } /* * @return Returns true if the shape is a {@link BlobShape} shape. / public final boolean isBlobShape() { return getType() == ShapeType.BLOB; } /* * @return Returns true if the shape is a {@link BooleanShape} shape. / public final boolean isBooleanShape() { return getType() == ShapeType.BOOLEAN; } /* * @return Returns true if the shape is a {@link ByteShape} shape. / public final boolean isByteShape() { return getType() == ShapeType.BYTE; } /* * @return Returns true if the shape is a {@link ShortShape} shape. / public final boolean isShortShape() { return getType() == ShapeType.SHORT; } /* * @return Returns true if the shape is a {@link FloatShape} shape. / public final boolean isFloatShape() { return getType() == ShapeType.FLOAT; } /* * @return Returns true if the shape is an {@link DocumentShape} shape. / public final boolean isDocumentShape() { return getType() == ShapeType.DOCUMENT; } /* * @return Returns true if the shape is an {@link DoubleShape} shape. / public final boolean isDoubleShape() { return getType() == ShapeType.DOUBLE; } /* * @return Returns true if the shape is a {@link ListShape} shape. / public final boolean isListShape() { return getType() == ShapeType.LIST; } /* * @return Returns true if the shape is a {@link SetShape} shape. / public final boolean isSetShape() { return getType() == ShapeType.SET; } /* * @return Returns true if the shape is a {@link IntegerShape} shape. / public final boolean isIntegerShape() { return getType() == ShapeType.INTEGER; } /* * @return Returns true if the shape is a {@link LongShape} shape. / public final boolean isLongShape() { return getType() == ShapeType.LONG; } /* * @return Returns true if the shape is a {@link MapShape} shape. / public final boolean isMapShape() { return getType() == ShapeType.MAP; } /* * @return Returns true if the shape is a {@link MemberShape} shape. / public final boolean isMemberShape() { return getType() == ShapeType.MEMBER; } /* * @return Returns true if the shape is an {@link OperationShape} shape. / public final boolean isOperationShape() { return getType() == ShapeType.OPERATION; } /* * @return Returns true if the shape is a {@link ResourceShape} shape. / public final boolean isResourceShape() { return getType() == ShapeType.RESOURCE; } /* * @return Returns true if the shape is a {@link ServiceShape} shape. / public final boolean isServiceShape() { return getType() == ShapeType.SERVICE; } /* * @return Returns true if the shape is a {@link StringShape} shape. / public final boolean isStringShape() { return getType() == ShapeType.STRING; } /* * @return Returns true if the shape is a {@link StructureShape} shape. / public final boolean isStructureShape() { return getType() == ShapeType.STRUCTURE; } /* * @return Returns true if the shape is a {@link UnionShape} shape. / public final boolean isUnionShape() { return getType() == ShapeType.UNION; } /* * @return Returns true if the shape is a {@link TimestampShape} shape. / public final boolean isTimestampShape() { return getType() == ShapeType.TIMESTAMP; } /* * Gets all of the members contained in the shape. * * @return Returns the members contained in the shape (if any). / public Collection<MemberShape> members() { return Collections.emptyList(); } @Override public ShapeId toShapeId() { return id; } @Override public final List<String> getTags() { return getTrait(TagsTrait.class).map(TagsTrait::getValues).orElseGet(Collections::emptyList); } @Override public final SourceLocation getSourceLocation() { return source; } @Override public int compareTo(Shape other) { return getId().compareTo(other.getId()); } @Override public final String toString() { return "(" + getType() + ": `" + getId() + "`)"; } @Override public int hashCode() { return getId().hashCode() + 3 getType().hashCode(); } @Override public boolean equals(Object o) { if (o == this) { return true; } else if (!(o instanceof Shape)) { return false; } Shape other = (Shape) o; return getId().equals(other.getId()) && getType() == other.getType() && traits.equals(other.traits); } } --- abstract: 'Quantum algorithms are usually described as monolithic circuits, becoming large at modest input size. Near-term quantum architectures can only manage a small number of qubits. We develop an automated method to distribute quantum circuits over multiple agents, minimising quantum communication between them. We reduce the problem to hypergraph partitioning and then solve it with state-of-the-art optimisers. This makes our approach useful in practice, unlike previous methods. Our implementation is evaluated on five quantum circuits of practical relevance.' author: - 'Pablo Andr[é]{}s-Mart[í]{}nez' - Chris Heunen bibliography: - 'Bibliography.bib' title: Automated distribution of quantum circuits via hypergraph partitioning --- [^1] [^2] Introduction ============ Quantum computation [@feynman; @nielsenchuang; @lloyd:simulators] employs the laws of quantum mechanics to design systems capable of outperforming classical computers in certain problems [@Shor; @Grover; @harrowhassadimlloyd:linear]. Over the past couple of decades, this idea has rapidly developed from theoretical results into actual quantum technology [@obrienfurusawavuckovic:photonic; @devoretschoelkopf:superconducting; @horodecki:entanglement]. Although there are other approaches [@raussendorfbriegel:mbqc], the dominant way to present a quantum algorithm is as a quantum circuit [@deutsch:networks]: a description of how quantum devices, chosen from a fixed finite set, are applied to different parts of the input system; see Figure \[fig:circuit\] for an example. Each of the ‘wires’ that quantum devices act upon typically consist of a two level quantum system called a quantum bit or qubit. The qubit count grows with the input size, and for relevant problems such as the unique shortest vector problem (with applications in cryptography [@USV]) the circuit grows large: lattice dimension 3 already requires 842 qubits and 95,624 gates [^3]. Near-term quantum computing architectures are not capable of executing such large circuits. We are currently entering the era of Noisy Intermediate-Scale Quantum (NISQ) technology [@NISQ], being able to fabricate small quantum computing units (QPU for short) ranging from $10$ to almost $100$ qubits. Much effort is being dedicated to further increase the number of qubits that QPUs can manage, but as the number of qubits grows, the challenge of addressing each qubit individually and shielding them from unwanted interactions and decoherence rapidly becomes unmanageable [@vanmeterdevitt:survey]. To scale up beyond this point, researchers are proposing distributed quantum architectures

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. Instructions for performing these tasks from the Administration Console are provided in the Administration Console online help. |link:../security-guide/toc.html#GSSCG[Security Guide] |Provides instructions for configuring and administering GlassFish Server security. |link:../application-deployment-guide/toc.html#GSDPG[Application Deployment Guide] |Explains how to assemble and deploy applications to the GlassFish Server and provides information about deployment descriptors. |link:../application-development-guide/toc.html#GSDVG[Application Development Guide] |Explains how to create and implement Java Platform, Enterprise Edition (Java EE platform) applications that are intended to run on the GlassFish Server. These applications follow the open Java standards model for Java EE components and application programmer interfaces (APIs). This guide provides information about developer tools, security, and debugging. |link:../add-on-component-development-guide/toc.html#GSACG[Add-On Component Development Guide] |Explains how to use published interfaces of GlassFish Server to develop add-on components for GlassFish Server. This document explains how to perform only those tasks that ensure that the add-on component is suitable for GlassFish Server. |link:../embedded-server-guide/toc.html#GSESG[Embedded Server Guide] |Explains how to run applications in embedded GlassFish Server and to develop applications in which GlassFish Server is embedded. |link:../ha-administration-guide/toc.html#GSHAG[High Availability Administration Guide] |Explains how to configure GlassFish Server to provide higher availability and scalability through failover and load balancing. |link:../performance-tuning-guide/toc.html#GSPTG[Performance Tuning Guide] |Explains how to optimize the performance of GlassFish Server. |link:../troubleshooting-guide/toc.html#GSTSG[Troubleshooting Guide] |Describes common problems that you might encounter when using GlassFish Server and explains how to solve them. |link:../error-messages-reference/toc.html#GSEMR[Error Message Reference] |Describes error messages that you might encounter when using GlassFish Server. |link:../reference-manual/toc.html#GSRFM[Reference Manual] |Provides reference information in man page format for GlassFish Server administration commands, utility commands, and related concepts. |link:../../openmq/mq-release-notes/toc.html#GMRLN[Message Queue Release Notes] |Describes new features, compatibility issues, and existing bugs for Open Message Queue. |link:../../openmq/mq-tech-over/toc.html#GMTOV[Message Queue Technical Overview] |Provides an introduction to the technology, concepts, architecture, capabilities, and features of the Message Queue messaging service. |link:../../openmq/mq-admin-guide/toc.html#GMADG[Message Queue Administration Guide] |Explains how to set up and manage a Message Queue messaging system. |link:../../openmq/mq-dev-guide-jmx/toc.html#GMJMG[Message Queue Developer's Guide for JMX Clients] |Describes the application programming interface in Message Queue for programmatically configuring and monitoring Message Queue resources in conformance with the Java Management Extensions (JMX). |link:../../openmq/mq-dev-guide-java/toc.html#GMJVG[Message Queue Developer's Guide for Java Clients] |Provides information about concepts and procedures for developing Java messaging applications (Java clients) that work with GlassFish Server. |link:../../openmq/mq-dev-guide-c/toc.html#GMCCG[Message Queue Developer's Guide for C Clients] |Provides programming and reference information for developers working with Message Queue who want to use the C language binding to the Message Queue messaging service to send, receive, and process Message Queue messages. |======================================================================= [[GSACG00080]][[giprl]] [[related-documentation]] Related Documentation ~~~~~~~~~~~~~~~~~~~~~ The following tutorials explain how to develop Java EE applications: * http://docs.oracle.com/javaee/7/firstcup/doc/home.html[Your First Cup: An Introduction to the Java EE Platform] (`http://docs.oracle.com/javaee/7/firstcup/doc/home.html`). For beginning Java EE programmers, this short tutorial explains the entire process for developing a simple enterprise application. The sample application is a web application that consists of a component that is based on the Enterprise JavaBeans specification, a JAX-RS web service, and a JavaServer Faces component for the web front end. * http://docs.oracle.com/javaee/7/tutorial/doc/home.html[The Java EE 7 Tutorial] (`http://docs.oracle.com/javaee/7/tutorial/doc/home.html`). This comprehensive tutorial explains how to use Java EE 7 platform technologies and APIs to develop Java EE applications. Javadoc tool reference documentation for packages that are provided with GlassFish Server is available as follows. * The API specification for version 7 of Java EE is located at `http://docs.oracle.com/javaee/7/api/`. * The API specification for GlassFish Server 4.0, including Java EE 7 platform packages and nonplatform packages that are specific to the GlassFish Server product, is located at `http://glassfish.java.net/nonav/docs/v3/api/`. Additionally, the http://www.oracle.com/technetwork/java/javaee/tech/index.html[Java EE Specifications] (`http://www.oracle.com/technetwork/java/javaee/tech/index.html`) might be useful. For information about creating enterprise applications in the NetBeans Integrated Development Environment (IDE), see the http://www.netbeans.org/kb/[NetBeans Documentation, Training & Support page] (`http://www.netbeans.org/kb/`). For information about the Java DB database for use with the GlassFish Server, see the http://www.oracle.com/technetwork/java/javadb/overview/index.html[Java DB product page] (`http://www.oracle.com/technetwork/java/javadb/overview/index.html`). The Java EE Samples project is a collection of sample applications that demonstrate a broad range of Java EE technologies. The Java EE Samples are bundled with the Java EE Software Development Kit (SDK) and are also available from the http://glassfish-samples.java.net/[Java EE Samples project page] (`http://glassfish-samples.java.net/`). [[GSACG00081]][[fwbkx]] [[typographic-conventions]] Typographic Conventions ~~~~~~~~~~~~~~~~~~~~~~~ The following table describes the typographic changes that are used in this book. [width="100%",cols="<14%,<37%,<49%",options="header",] |======================================================================= |Typeface |Meaning |Example |`AaBbCc123` |The names of commands, files, and directories, and onscreen computer output a| Edit your `.login` file. Use `ls` `a` to list all files. `machine_name% you have mail.` |`AaBbCc123` |What you type, contrasted with onscreen computer output a| `machine_name%` `su` `Password:` |AaBbCc123 |A placeholder to be replaced with a real name or value |The command to remove a file is `rm` filename. |AaBbCc123 |Book titles, new terms, and terms to be emphasized (note that some emphasized items appear bold online) a| Read Chapter 6 in the User's Guide. A cache is a copy that is stored locally. Do not save the file. |======================================================================= [[GSACG00082]][[fquvc]] [[symbol-conventions]] Symbol Conventions ~~~~~~~~~~~~~~~~~~ The following table explains symbols that might be used in this book. [width="100%",cols="<10%,<26%,<28%,<36%",options="header",] |======================================================================= |Symbol |Description |Example |Meaning |`[ ]` |Contains optional arguments and command options. |`ls [-l]` |The `-l` option is not required. |`{ \| }` |Contains a set of choices for a required command option. |`-

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heelsfuck, double penetration .... and if you want something new I will try Do it for yoHouse Speaker Nancy Pelosi, D-Calif., on Thursday accused the White House of a "cover up," hours after the public release of a whistleblower's complaint alleging that President Donald Trump tried to solicit Ukraine to interfere in the 2020 election — and the administration sought to conceal that effort. "This is a cover-up. This is a cover-up," Pelosi repeared at her weekly press conference, her first since announcing a formal impeachment inquiry into Trump on Tuesday evening. Advertisement: Pelosi went on to read aloud a part of the whistleblower's complaint alleging that the White House had intervened to "lock down" all records of a July 25 phone call between Trump and Ukrainian President Volodymyr Zelensky. The call is at the center of the complaint. The whistleblower alleged the administration placed the transcript of Trump's call with Zelensky into a "computer system managed directly by the National Security Council (NSC) Directorate for Intelligence Programs," which the whistleblower described as a "standalone computer system reserved for codeword-level intelligence information, such as covert action." "According to White House officials I spoke with, this was 'not the first time' under this administration that a presidential transcript was placed into this codeword-level system solely for the purpose of protecting politically sensitive — rather than national security sensitive — information," the whistleblower wrote. Advertisement: Pelosi said those actions constituted a "cover-up." House Democrats have decided to narrow the focus of their inquiry to the allegations detailed in the whistleblower's complaint, she said. "Our consensus in our caucus is we will proceed under the auspices of where this matter is relevant and that is the Intelligence Committee," she added. The complaint alleged that Trump urged Zelensky to "initiate or continue an investigation" into Hunter Biden, the son of Joe Biden, who is currently vying for the Democratic nomination to challenge the president in the 2020 election. Advertisement: Trump also asked Zelensky to investigate allegations that Russian interference in the 2016 originated in Ukraine "with a specific request that the Ukrainian leader locate and turn over servers used by the Democratic National Committee (DNC) and examined by the U.S. cyber security firm CrowdStrike," the whistleblower alleged. (The emails of 2016 Democratic presidential nominee, Hillary Clinton, were hacked by Russian intelligence officials ahead of the 2016 election, as concluded by CrowdStrike. There is no evidence the server hacked by Russian agents in 2016 may have been hidden in Ukraine, as the president suggested.) Pelosi said she has not given committee chairs any deadlines, and only the facts would determine the schedule of the inquiry. Advertisement: "The timeline relates to how the Intelligence Committee proceeds and our timeline will spring from them," Pelosi said. (Notably, the House Judiciary Committee is the congressional panel that would draft articles of impeachment.) The speaker noted there was "no rush to judgement" on how House Democrats would proceed with their impeachment inquiry into Trump. She pointed out that while some members in her caucus want to rush into impeachment, it is important to "have an inquiry to further establish the facts." "We have to make a judgement in an inquiry as we go forward . . . There are some in our caucus who think, 'let's just have an impeachment.' No, we have to have an inquiry to further establish the facts," she said. "There is no rush to judgement and in some ways we are a jury — open to what might be exculpatory or not." Advertisement: "But every day, the sadness grows because the disregard for our Constitution that the President has becomes more clear," she continued. Pelosi underscored that the president's actions, as described in the whistleblower's complaint, "lifts this to a whole new terrain, a whole new level of concern about his lawlessness." "Use any metaphor you want — crossing the Rubicon, a new day has dawned . . ." she continued. "The facts are these: that the president of the United States, in his actions in a telephone call with a head of state, betrayed his office, our national security and the integrity of our election." Advertisement: "It's not the role of the president to shake down foreign leaders for his own political purposes, withholding taxpayer money to do so," she said. Her comments came as the acting director of national intelligence, Joseph Maguire, testified before the House Intelligence Committee about the complaint at a public hearing. Speaking of Maguire's decision to withhold the complaint from Congress last week, Pelosi said, "I think what the DNI did was [break] the law. The law is very clear — the DNI 'shall' convey the complaint to the Intelligence Committee."VisitBritain Shop is the official shop of the British Tourist Board, and has everything you need for a great trip to Britain, including travelcards, rail passes and tickets to a variety of attractions. Plan out your entire trip in advance, and save money at the same time! Britain Insider: A Local’s Guide To The Ultimate Weekend in Edinburgh Thursday 08 March 2018 A weekend in Britain always brims with local flavor, but it’s especially delicious when spent in the Scottish capital of Edinburgh. Amongst castles, cobbled streets, parks and museums, this historic region hosts more Michelin-starred restaurants than any other city in Britain outside London. (YUM.) Edinburgh local, Kate Bouchier-Hayes, has lived in the city for well over a decade. We polled the roller derby player and public relations professional on her favorite workouts, culture trips and, most importantly, FOOD for our Britain Insiders series. As it turns out, her responses make a picture-perfect weekender’s guide to the city. Edinburgh is a big city! Tell us about your neighborhood, Leith. I moved to Edinburgh about 15 years ago -- during that time, I've lived in quite a few different parts of the city, but Leith is my favourite. It has its own identity and character, and it’s a buzzing creative community in its own right. Leith is located just out of the city centre in Edinburgh's historic dock area, which gives it a strong sense of place. Leith provides the best of all worlds in that you have the stunning historic buildings and old maritime references that Edinburgh is famous for (which can be spotted throughout The Shore area), peace and tranquility (as offered by long walks along the Water of Leith), and a buzzing atmosphere created by fantastic bars and restaurants. Describe your typical weekend. 9 a.m. -- ExerciseI try and strike a balance in my weekends, so I like to get out for a decent walk (possibly to blow the cobwebs away from the night before!) in the morning. In Edinburgh, we are lucky to have a cracking range of options on our doorstep, many of which won’t be traditionally associated with the city. There’s a bracing beach walk along the old promenade at Portobello, a peaceful dander up the Water of Leith, or if you're feeling a bit more energetic, a climb up Arthur’s Seat. It’s always a challenge, but the sweeping views at the top of the sleeping volcano are always worth it! Aside from walks, jogging and outdoor bootcamps are big in Edinburgh, as the city's landscape is naturally so well-suited to challenging routes. I myself play roller derby with the Auld Reekie Roller Girls -- it’s not something Edinburgh is well-known for, but we actually have the biggest team in Scotland and one of the top-ranked in the UK! Exercise quota met, I usually catch up with pals for a bite to eat and a chat. Firm favorites for brunch and lunch right now are Urban Angel (always book ahead!), Roseleaf and Harmonium, a fab new vegan restaurant at The Shore. In recent years, Leith's exciting creative community has really developed, which is also key to what makes the area so special. New galleries and artist spaces are popping up, including the recently reopened Leith Custom House. This year, numerous venues in Leith, like the historic Leith Theatre, will be used as performance spaces as part of Edinburgh's famous Festivals. One of Edinburgh’s best qualities is how walkable it is. After living in the city for over 15 years, it amazes me that I still discover new parts of it. Exploring the Old Town on foot is certainly a must-do: the city is a warren of medieval cobbled streets and historical gems! I also love escaping to the rooftop terrace at The National Museum of Scotland, which has one of the most amazing 360-degree views of the city. 7 p.m. -- Dinner I LOVE eating. Seriously. Edinburgh has more restaurants per capita than any British city outside of London, so there's always plenty to choose from! For me, Edinburgh’s dining scene stands out in terms of quality and diversity. No matter your budget -- from a Michelin-starred restaurant to the most exciting street food and fresh produce markets -- Edinburgh has something to fit the bill. We've seen a few trends really grab the culinary scene recently: First it was burgers (Bread Meats Bread, Holyrood 9A, Nobles), then authentic Mexican food (El Cartel, Bodega, Topolabamba), and now it seems to

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, and countless other facets of the film are drawn from all over the continent and its diaspora, in a science-fiction celebration of the imaginary country of Wakanda, a high-tech utopia that is a fictive manifestation of African potential unfettered by slavery and colonialism. But it is first and foremost an African American love letter, and as such it is consumed with The Void, the psychic and cultural wound caused by the Trans-Atlantic slave trade, the loss of life, culture, language, and history that could never be restored. It is the attempt to penetrate The Void that brought us Alex Haley’s Roots, that draws thousands of African Americans across the ocean to visit West Africa every year, that left me crumpled on the rocks outside the Door of No Return at Gorée Island’s slave house as I stared out over a horizon that my ancestors might have traversed once and forever. Because all they have was lost to The Void, I can never know who they were, and neither can anyone else. In Cyprus, Estonia, the United Arab Emirates, and elsewhere, passports can now be bought and sold. “If you believe you are a citizen of the world, you are a citizen of nowhere. You don’t understand what citizenship means,” the British prime minister, Theresa May, declared in October 2016. Not long after, at his first postelection rally, Donald Trump asserted, “There is no global anthem. No global currency. No certificate of global citizenship. We pledge allegiance to one flag and that flag is the American flag.” And in Hungary, Prime Minister Viktor Orbán has increased his national-conservative party’s popularity with statements like “all the terrorists are basically migrants” and “the best migrant is the migrant who does not come.” Citizenship and its varying legal definition has become one of the key battlegrounds of the 21st century, as nations attempt to stake out their power in a G-Zero, globalized world, one increasingly defined by transnational, borderless trade and liquid, virtual finance. In a climate of pervasive nationalism, jingoism, xenophobia, and ever-building resentment toward those who move, it’s tempting to think that doing so would become more difficult. But alongside the rise of populist, identitarian movements across the globe, identity itself is being virtualized, too. It no longer needs to be tied to place or nation to function in the global marketplace. Deputy Attorney General Ron Rosenstein flew to Seattle for a press conference at which he announced little, but may have said a great deal. Back in the fall of 2001, exactly one month after the 9/11 attacks, a lawyer in Seattle named Tom Wales was murdered as he worked alone at his home computer at night. Someone walked into the yard of Wales’s house in the Queen Anne Hill neighborhood of Seattle, careful to avoid sensors that would have set off flood lights in the yard, and fired several times through a basement window, hitting Wales as he sat at his desk. Wales survived long enough to make a call to 911 and died soon afterwards. He was 49, divorced, with two children in their 20s. The crime was huge and dismaying news in Seattle, where Wales was a prominent, respected, and widely liked figure. As a young lawyer in the early 1980s he had left a potentially lucrative path with a New York law firm to come to Seattle and work as an assistant U.S. attorney, or federal prosecutor. That role, which he was still performing at the time of his death, mainly involved prosecuting fraud cases. In his off-duty hours, Wales had become a prominent gun-control advocate. From the time of his death onward, the circumstances of the killing—deliberate, planned, nothing like a robbery or a random tragedy—and the prominence of his official crime-fighting record and unofficial advocacy role led to widespread assumption that his death was a retaliatory “hit.” The Justice Department considers him the first and only U.S. prosecutor to have been killed in the line of duty. A week after 17 people were murdered in a mass shooting at Marjory Stoneman Douglas High School in Parkland, Florida, teenagers across South Florida, in areas near Washington, D.C., and in other parts of the United States walked out of their classrooms to stage protests against the horror of school shootings and to advocate for gun law reforms. A week after 17 people were murdered in a mass shooting at Marjory Stoneman Douglas High School in Parkland, Florida, teenagers across South Florida, in areas near Washington, D.C., and in other parts of the United States walked out of their classrooms to stage protests against the horror of school shootings and to advocate for gun law reforms. Student survivors of the attack at Marjory Stoneman Douglas High School traveled to their state Capitol to attend a rally, meet with legislators, and urge them to do anything they can to make their lives safer. These teenagers are speaking clearly for themselves on social media, speaking loudly to the media, and they are speaking straight to those in power—challenging lawmakers to end the bloodshed with their “#NeverAgain” movement. Why the ingrained expectation that women should desire to become parents is unhealthy In 2008, Nebraska decriminalized child abandonment. The move was part of a “safe haven” law designed to address increased rates of infanticide in the state. Like other safe-haven laws, parents in Nebraska who felt unprepared to care for their babies could drop them off in a designated location without fear of arrest and prosecution. But legislators made a major logistical error: They failed to implement an age limitation for dropped-off children. Within just weeks of the law passing, parents started dropping off their kids. But here's the rub: None of them were infants. A couple of months in, 36 children had been left in state hospitals and police stations. Twenty-two of the children were over 13 years old. A 51-year-old grandmother dropped off a 12-year-old boy. One father dropped off his entire family—nine children from ages one to 17. Others drove from neighboring states to drop off their children once they heard that they could abandon them without repercussion. Here are some readers with extra elements on this discussion—political, cultural, international. First, an American reader on the interaction of current concepts of masculinity and the nearly all-male population of mass gun murderers: The path to its revival lies in self-sacrifice, and in placing collective interests ahead of the narrowly personal. The death of liberalism constitutes the publishing world’s biggest mass funeral since the death of God half a century ago. Some authors, like conservative philosopher Patrick Deneen, of Why Liberalism Failed, have come to bury yesterday’s dogma. Others, like Edward Luce (The Retreat of Western Liberalism), Mark Lilla (The Once and Future Liberal), and Steven Levitsky and Daniel Ziblatt (How Democracies Die) come rather to praise. I’m in the latter group; the title-in-my-head of the book I’m now writing is What Was Liberalism. But perhaps, like God, liberalism has been buried prematurely. Maybe the question that we should be asking is not what killed liberalism, but rather, what can we learn from liberalism’s long story of persistence—and how can we apply those insights in order to help liberalism write a new story for our own time. A new study explores a strange paradox: In countries that empower women, they are less likely to choose math and science professions. Though their numbers are growing, only 27 percent of all students taking the AP Computer Science exam in the United States are female. The gender gap only grows worse from there: Just 18 percent of American computer-science college degrees go to women. This is in the United States, where many college men proudly describe themselves as “male feminists” and girls are taught they can be anything they want to be. Meanwhile, in Algeria, 41 percent of college graduates in the fields of science, technology, engineering, and math—or “STEM,” as it’s known—are female. There, employment discrimination against women is rife and women are often pressured to make amends with their abusive husbands. According to a report I covered a few years ago, Jordan, Qatar, and the United Arab Emirates were the only three countries in which boys are significantly less likely to feel comfortable working on math problems than girls are. In all of the other nations surveyed, girls were more likely to say they feel “helpless while performing a math problem.” The president’s son is selling luxury condos and making a foreign-policy speech. Who does Donald Trump Jr. speak for? Does the president’s son speak for the Trump Organization as he promotes luxury apartments in India? Does he speak for himself when he dines with investors in the projects? Does he speak for the Trump administration as he makes a foreign-policy speech in Mumbai on Friday? “When these sons go around all over the world talking about, one, Trump business deals and, two, … apparently giving speeches on some United States government foreign policy, they are strongly suggesting a linkage between the two,” Richard Painter, President George W. Bush’s chief ethics lawyer who is a professor of law at the University of Minnesota, told me. “Somebody, somewhere is going to cross the line into suggesting a quid pro quo.”If permissions to modify an Organizational Unit (OU) are intentionally or accidentally delegated to a user who shouldn’t have them, it can lead to leakage of sensitive data. For example, a user with these

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-0068642-g003){ref-type="fig"}. Bacteria retrieved from those plants were predominantly represented by members of the Leuconostocaceae, Bacillaceae, and Streptococcaceae families ([Figure 3B)](#pone-0068642-g003){ref-type="fig"} and specifically classified as species of *Leuconostoc* *,* *Lactococcus* *, Bacillus*, and *Exiguobacterium* ([Figure 5)](#pone-0068642-g005){ref-type="fig"}. ![Bacterial diversity phyllosphere differs between season of planting.\ The UPGMA dendrogram was made in QIIME using weighted UniFrac distance data between phyllosphere microbiota from 223 plants. Tree branches in blue correspond to plants from the E09 and E10 trials and red branches represent samples from the L09 and L10 trials. Clusters I and II were identified as two major sample groups. Relative sequence abundances of the top 21 taxonomic groups are shown in the order of sequence abundance. The heat map indicates a range of proportional sequence abundance in each sample (minimum: 0%; maximum: 87%).](pone.0068642.g005){#pone-0068642-g005} Temporal and irrigation effects on the phyllosphere microbiota {#s3.5} -------------------------------------------------------------- Within individual field trials, the bacterial composition on lettuce was typically distinct at each time point ([Table 1)](#tab1){ref-type="table"}. These differences were at least partially explained by the increased Phylogenetic Diversity (alpha-diversity) on leaves from plants collected at 21 dpi compared to plants at either 7 or 14 dpi ([Figure 6)](#pone-0068642-g006){ref-type="fig"}. The Chao1 species richness metric also positively correlated with the PD estimator (r^2^=0.89, data not shown). Similarly, temporal changes in the bacterial diversity were identified according to PCoA on Unifrac distances. For example, a temporal change in bacterial composition on lettuce was evident between 7 dpi and 21 dpi in L10 ([Figure 7A)](#pone-0068642-g007){ref-type="fig"}. At 14 dpi, the microbiota were typically similar to plants collected at either 7 dpi or 21 dpi, possibly indicating a transition from lower to higher bacterial diversity ([Figure 7A)](#pone-0068642-g007){ref-type="fig"}. ###### Cluster quality using weighted UniFrac community analysis. **E09** **L09** **E10** **L10** ---------------------------- --------- --------- --------- --------- Day (dpi) 1.129\* 1.298\* 1.138 1.113\* Irrigation method 1.018 1.057 1.114 1.006 *E. coli* O157 inoculation 1.002 1.004 1.172\* 1.031 *E. coli* O157 persistence 0.992 0.967 1.045 1.026 Cluster quality was calculated based on the dissimilarity ratio between/within clusters of samples in a treatment group where a high ratio signifies a distinct cluster. The distance matrices from the weighted UniFrac analysis were used to compute the dissimilarity ratio. \* The highest cluster quality ratio observed in a given planting. ![Leaf age influences the diversity of phyllosphere microbial diversity.\ The Phylogenetic Diversity (PD) of the phyllosphere microbiota from leaves of different ages (dpi). The average ± standard error for all plants the four field trials is shown. n= 73, 84, and 66 for 7, 14, and 21 dpi, respectively; \* *P* ≤ 0.001 by the Kruskal-Wallis multiple comparisons test. ns: not significant.](pone.0068642.g006){#pone-0068642-g006} ![Phyllosphere microbiota differs due to effects of the day of collection, irrigation, and inoculation of *E. coli* O157:H7.\ Phyllosphere microbiota identified during the L10 were analyzed by Principal Coordinates Analysis (PCoA) performed on Unifrac distances between bacterial communities collected from plants on different days (A), and for plants at 14 dpi exposed to drip or overhead irrigation (B), the inoculation of *E. coli* O157:H7 (C), or inoculated plants that were InocPOS or InocNEG (D). Weighted UniFrac distances were used for (A), (C), and (D) and unweighted UniFrac distances were used for (B). The plots are representative of findings for the other field trials and time points. Additional PCoA plots are in [Figure S7](#pone.0068642.s007){ref-type="supplementary-material"}.](pone.0068642.g007){#pone-0068642-g007} To identify irrigation-dependent effects on the microbiota, it was necessary to compare plants collected on the same day. UniFrac distances examined using ANOSIM revealed that the microbiota on sprinkler- and drip-irrigated plants were significantly different from each other for eight out of the 12 time points sampled ([Table 2)](#tab2){ref-type="table"}. The irrigation effects found for one day are shown in [Figure 7B](#pone-0068642-g007){ref-type="fig"}. Although no single genus consistently distinguished the bacterial communities between drip and sprinkler irrigated plants, *Xanthomonas* was typically more abundant on sprinkler-irrigated plants and *Erwinia* was enriched on drip-irrigated plants (data not shown). The relative abundance of *Leuconostoc* and *Lactococcus* was also higher on drip-irrigated plants, but only for E09 and E10 plantings. ###### ANOSIM cluster analysis of the phyllosphere microbiota between sprinkler- and drip-irrigated Romaine lettuce plants. **E09** **L09** **E10** **L10** -------------------- --------- --------- ------------------------------ ------------------------------ --- -------------------------------- ---------------------------------- -------------------------------- ------- ---------------------------------- -------------------------------- -------------------------------- Unweighted UniFrac -0.02 -0.006 0.1 **0.13** [**\***](#ngtab2.1) 0 **0.55** [**\*\***](#ngtab2.2) 0.22 **0.44** [**\*\***](#ngtab2.2) 0.013 **0.36** [**\*\*\***](#ngtab2.3) **0.33** [**\*\***](#ngtab2.2) **0.42** [**\*\***](#ngtab2.2) Weighted UniFrac -0.16 -0.068 **0.22** [**\***](#ngtab2.1) **0.13** [**\***](#ngtab2.1) 0 0.12 **0.67** [**\*\*\***](#ngtab2.3) **0.44** [**\*\***](#ngtab2.2) 0.063 -0.029 0.0026 -0.13 The R-statistic is shown for each comparison of clusters of differentially irrigated plants. \* 0.05 \< *P* ≤ 0.1; \*\* 0.01 \< *P* ≤ 0.05; \*\*\**P* ≤ 0.01 The phyllosphere microbiota differed on plants inoculated with *Escherichia coli* O157:H7 {#s3.6} ----------------------------------------------------------------------------------------- Inoculation of *E. coli* O157:H7 altered the phyllosphere to the extent that the lettuce microbiota differed between inoculated and control plants for 10 of the 12 time points examined ([Figure S7](#pone.0068642.s007){ref-type="supplementary-material"}). The result for one of the time points, 14 dpi in L10, is shown in [Figure 7C](#pone-0068642-g007){ref-type="fig"}. Notably, the phyllosphere microbiota recovered from naive (not sprayed) and buffer-only inoculated plants were indistinguishable and differences associated with other factors were more important determinants of the bacterial diversity ([Figure 7C and S8)](#pone-0068642-g007){ref-type="fig"}. Therefore the differences in bacterial inhabitants were most likely due to *E. coli* O157:H7 and not the 0.1% peptone buffer used to deliver the pathogen onto the lettuce. The bacterial community composition was also distinct between InocPOS and InocNEG plants for nine of the 12 time points sampled, including 14 dpi in L10 ([Figure 7D)](#pone-0068642-g007){ref-type="fig"}. These differences were partially associated with the enrichment of certain bacteria. For example, at 14 dpi in L10, *Erwinia* was significantly enriched in the phyllosphere of InocNEG plants (*P* ≤ 0.05) according to the Kruskal-Wallis multiple comparison test. *Erwinia* was also enriched on InocNEG plants 2.7-fold and 9.2-fold at 14 and 21 dpi in the L09 trial. However, the

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type="ref"} Interestingly, our current study demonstrates the induction of protein synthesis after ECC coincides with reduced AMPK activation in tumour‐bearing mice. Furthermore, reduced AMPK activation after a single ECC bout has also recently been observed in castrated mice.[51](#jcsm12271-bib-0051){ref-type="ref"} These findings are in contrast to our previous observations using low‐frequency electrical stimulation and point to the differential regulation of muscle metabolic signalling by different types of contraction. We previously found a sustained AMPK activation following a single bout of low‐frequency concentric contractions in cachectic skeletal muscle.[32](#jcsm12271-bib-0032){ref-type="ref"} The specificity of the responses induced by different types of contractions may be related to metabolic stress as cachectic muscle develops mitochondrial dysfunction.[52](#jcsm12271-bib-0052){ref-type="ref"}, [53](#jcsm12271-bib-0053){ref-type="ref"}, [54](#jcsm12271-bib-0054){ref-type="ref"} The cachectic muscle\'s anabolic and metabolic response to different contraction types will require further investigation. Nonetheless, our findings suggest that ECC may be a potential therapeutic treatment to promote muscle anabolism during cancer cachexia progression. Muscle signalling related to inflammation, energy status, and proteostasis are disrupted during cachexia progression and have been implicated in the regulation of muscle wasting.[55](#jcsm12271-bib-0055){ref-type="ref"}, [56](#jcsm12271-bib-0056){ref-type="ref"} Interestingly, many of these same pathways are induced by muscle contraction and exercise.[57](#jcsm12271-bib-0057){ref-type="ref"} IL‐6 and muscle STAT3 signalling through the gp130 receptor are activated during the progression of cachexia[30](#jcsm12271-bib-0030){ref-type="ref"}, [52](#jcsm12271-bib-0052){ref-type="ref"}, [58](#jcsm12271-bib-0058){ref-type="ref"} and are associated with mTORC1 and protein suppression in pre‐clinical cachexia models.[7](#jcsm12271-bib-0007){ref-type="ref"}, [28](#jcsm12271-bib-0028){ref-type="ref"} Inhibition of muscle IL‐6 signalling through either direct STAT3 inhibition or gp130 loss can attenuate wasting in mouse models of cachexia.[30](#jcsm12271-bib-0030){ref-type="ref"}, [31](#jcsm12271-bib-0031){ref-type="ref"} We have previously found that short‐term PDTC treatment attenuated the suppression of mTORC1 signalling and protein synthesis while concomitantly reducing muscle STAT3 and NFκB activation in *Apc* ^*Min/+*^ mice.[29](#jcsm12271-bib-0029){ref-type="ref"}, [32](#jcsm12271-bib-0032){ref-type="ref"} We extend these findings by demonstrating a single PDTC dose improved basal protein synthesis. It has recently been suggested that intermittent cycles of pathway inhibition/activation may be required to combat muscle wasting during cancer cachexia.[59](#jcsm12271-bib-0059){ref-type="ref"} Indeed, many cytokine‐related signalling pathways have established roles in myogenesis[60](#jcsm12271-bib-0060){ref-type="ref"} and load‐induced muscle growth and remodelling.[41](#jcsm12271-bib-0041){ref-type="ref"}, [42](#jcsm12271-bib-0042){ref-type="ref"}, [61](#jcsm12271-bib-0061){ref-type="ref"} Therefore, we utilized an experimental paradigm that lowered chronic muscle inflammatory signalling but did not block contraction‐induced signalling.[32](#jcsm12271-bib-0032){ref-type="ref"} Importantly, we found that PDTC treatment increased both basal and ECC‐induced protein synthesis in cachectic muscle. These findings demonstrate that cachectic muscle retains the anabolic capacity to increase protein synthesis, and inflammatory signalling contributes to the suppression of these processes. Additional research is warranted to determine the specific mechanisms related to STAT3 and NFκB that serve to diminish the capacity for protein synthesis in cachectic muscle. Moreover, further research is also required to determine the effect of muscle inflammatory signalling on metabolic remodelling in response to repeated contraction bouts, which could dramatically impact health outcomes related to exercise. Conclusions {#jcsm12271-sec-0023} ----------- In summary, we examined cachectic muscle\'s ability to induce protein synthesis in response to ECC and determined the role of muscle inflammatory signalling involving STAT3 and NFκB on ECC‐induced anabolic signalling. We found that mechano‐sensitive signalling pathways related to P38, ERK1/2, and Akt were not altered by the cachectic environment in wasting muscle. While cachexia did not attenuate the ECC induction of mTORC1 signalling, the capacity for protein synthesis remained suppressed compared with healthy controls. Interestingly, we found that reducing muscle STAT3/NFκB signalling improved basal and ECC‐induced protein synthesis during severe cachexia. These studies demonstrate that mechano‐sensitive signalling pathways are maintained in skeletal muscle, but STAT3/NFκB signalling serves to attenuate basal and ECC‐induced protein synthesis. Further work is necessary to determine whether intermittent anti‐inflammatory therapies combined with exercise training may be useful to alleviate suppressed muscle protein synthesis during cancer cachexia. Conflict of interest {#jcsm12271-sec-0026} ==================== Justin P. Hardee, Brittany R. Counts, Song Gao, Brandon N. VanderVeen, Dennis K. Fix, Ho‐Jin Koh,, and James A. Carson declare that they have no conflict of interest. The authors thank Gaye Christmus and Dr Bradley Gordon for editorial review of the manuscript. This work was supported by National Institutes of Health \[grants R01 CA‐121249 (National Cancer Institute) and P20 RR‐017698 (National Institute of General Medical Science)\] to J.A.C, SPARC Graduate Research Grant from the Office of the Vice President for Research at the University of South Carolina to J.P.H and an ACSM Foundation Research Grant from the American College of Sports Medicine Foundation to J.P.H. The authors certify that they comply with the ethical guidelines for authorship and publishing of the Journal of Cachexia, Sarcopenia and Muscle.[62](#jcsm12271-bib-0062){ref-type="ref"} Q: Split duplicates in lists using LINQ So far I have this code public class Card { public int suitID; public int cardValue; } public class DeckManager { private List<List<Card>> FindCardsPerSuit(List<Card> cards) { var _cardsCombination = cards .GroupBy(x => x.cardValue) .Where(g => g.Count() > 2) .Select(c => c.ToList()) .ToList(); return _cardsCombination; } } I'm working on a Rummy card game and what I'm trying to do is to find if the combination of cards that the player want to play is valid or not. When the player selects some cards from the hand, I need to check if the cards with the same value have a unique suit, otherwise, add it to a new list. Example: The player has 8 cards all with the same value but different suits, the min combination is 4 so you can do 2 combinations, and because you play with 2 decks you have 2 cards per suit. How can I find out if I want to create a list of lists of combinations? At the moment the _cardsCombination query gets all the cards selected and make a smaller group with all the cards with the same value. How can I do the same thing and create subgroups for each card with suit duplicate? Thank you. A: var _cardsCombination = cards .GroupBy(x => x.cardValue) .SelectMany(g => { // group cards by suit var cardsPerSuit = g.GroupBy(c => c.suitId); // max number of cards with same suit (will be 1 or 2 for two decks) // this will be number of subsets var maxCardsPerSuit = cardsPerSuit.Max(gg => gg.Count()); return Enumerable // create subset for each setNumber from 0 to maxCardsPerSuit - 1 .Range(0, maxCardsPerSuit) .Select(setNumber => cardsPerSuit // take nth card from each suit .Select(s => s.ElementAtOrDefault(setNumber)) // skip nulls .Where(s => s != null) ); }) .Where(g => g.Count() > 2) .Select(c => c.ToList()) .ToList(); McConnell Aid: “She’s clearly, this sounds extreme, but she is emotionally unbalanced. I mean it’s been documented. . . she’s suffered some suicidal tendencies. She was hospitalized for 42 days when she had a mental breakdown in the ’90s.” There are also allegations that Jud

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answer special about the virus, spending most of his time talking about the way America could use the crisis to enact their leftist energy policies. Biden recalled the Great Depression, noting former President Franklin Roosevelt used that crisis to enact dramatic government programs, something he also wanted to do. “It’s like the New Deal,” he said. “Think of every great act that — every great change that has taken place. It’s come out of a crisis.” Biden proposed a similar dramatic surge in government spending for green energy infrastructure, including 550,000 charging stations for electric cars, windmills and solar panels, as well as spending for better battery technology. Biden said the coronavirus crisis would lead the American people to recognize the need for change, especially for workers and Americans suffering the effects of “systemic racism.” “It’s like the Band-Aid has been ripped off,” Biden said. The former vice president’s hat-tip to the Green New Deal comes as prominent leftist Rep. Alexandria Ocasio-Cortez has criticized his climate change platform. “I don’t think that the vice president has a climate change policy that is sufficient right now,” Ocasio-Cortez said in a recent interview.What others say: I just want to thank you again for representing me. You have provided so much for the kids and me that I could not properly put into words. I can say that I have a new measure of freedom, safety, boundaries, strength and peace that prior to meeting you I did not have. Thank you for standing firm for me when no one else would and when I didn't know how to. -- J.U., Marysville,WA In a time that was very difficult and painful, Paul worked on my behalf and for my children. He took charge, fought for us and steered us through. He did this in a way that caused us to feel safe in the midst of turmoil. I will be forever thankful for his expertise and his kindness. -- C.B., Bellevue, WA I have worked with other attorneys before and I have to say that my experience with Mr. Petry was the best. He really took good care of my case, made me aware of my options, and went above and beyond to help not only provide counsel, care and concern for me, but worked his best to achieve the best outcome between the different parties' grievances. Without any reservations, I recommend Paul Petry to anyone seeking legal counsel and advice.-- A.A., Seattle, WA Paul Petry was very professional, encouraging and supportive during my painful divorce, while also highly skilled at reaching a fair settlement in a short amount of time, though never rushing my divorce to finality. He kept my legal costs to a minimum and did not try to lengthen his services with unnecessary meetings. I noticed he worked very well with others in the legal community, yet maintained my interests as his first priority without negativity toward my ex-husband or his legal counsel. Throughout the process, Paul consistently advised me of options to consider in order to protect my emotional, financial and legal well-being.-- I.H., Issaquah, WAQ: ASP.NET Core 2.1 - Stack overflow exception related to dependency injection I'm getting a stack overflow exception after I load 4 or 5 times a simple controller action. The web app is running on Azure and I was able to dump the exception information and the problem seems to be related to Dependency Injection. internal object GetService(Type serviceType, ServiceProviderEngineScope serviceProviderEngineScope) { if (_disposed) { ThrowHelper.ThrowObjectDisposedException(); --> this is executed } var realizedService = RealizedServices.GetOrAdd(serviceType, _createServiceAccessor); _callback?.OnResolve(serviceType, serviceProviderEngineScope); return realizedService.Invoke(serviceProviderEngineScope); } Running the web app in my computer has no issues, it only fails in PROD. This is how I captured the exception in Azure: https://blogs.msdn.microsoft.com/benjaminperkins/2017/06/28/capture-a-stackoverflowexception-and-make-a-dump-0xc00000fd/ I opened the dump in Visual Studio and I could identify the code line where it failed (described above) but I still don't know how to fix it. All my dependencies are resolved with 'scope' lifetime. Any help is appreciated. A: I finally fixed it! I had a class that had like 20 dependencies and each dependency had more dependencies, maybe 4 or 5 level. There were no circular dependencies because this was working fine in my development environment. After I did a refactoring and reduced the dependencies, it worked out fine. Because it was working fine in my development environment but not in Azure App Service, I assume there's some limitation on the dependency instances or levels you can define when the app is hosted in Azure. This was my methodology to fix it: 1) Find the simplest case that fails. 2) Comment out all the depedencies and try again. It worked, ok, it's about dependencies. 3) Dump the stack overflow exception in production as this error didn't occur in the dev environment. 4) Confirm it's a dependency injection issue and examine .NET Core source code. 5) Reduce dependency instances and levels. 6) Deploy. If it doesn't work, go to (5). If it works, you are happy again :) Our Top 5 Instagram Tips for 2019 Instagram is quickly becoming a go-to platform for businesses across the United States and Scottsdale-based the spr agency, an award-winning social media and public relations agency, has released its top 5 tips for succeeding on the platform in 2019. Be Authentic The rush to capitalize on the popularity of any social media platform may also bring snap decisions on just what a company should post. Many companies chase trends instead of setting them. “While it’s easy to duplicate what others in your industry or vertical are doing, it’s more important to be authentic and true to your brand,” said Al Stevens, president and founder of the spr agency. “Social media users know when you’re phoning it in. They know when you’re not being yourself. And with all marketing, it’s important to speak authentically and provide a unique perspective.” Be Creative While authenticity is a must, it’s also important to be creative in your approach. “Given the number of Instagram posts that hit the platform’s news feed each day, Instagram users want to see originality and the spark of creativity,” said Christy Stevens, vice president of the spr agency. “They’re looking for posts that will inspire and entertain them. That’s what they choose to engage with when they double-tap a photo.” Great Photography Makes Great Content Investing in quality images is a must on any social media platform but it’s key to engaging Instagram users. There is a direct correlation between great photography and high engagement on Instagram. “Think of what inspires you and what will inspire your customers,” Al Stevens said. “If you’re not excited by the image you choose, how will your customers and followers be? You have to believe in each image and be willing to defend your job with the photo selection you make. It’s that important.” Hashtags Matter Thinking about throwing a few hashtags on that Instagram post? Don’t – at least not without researching the hashtags that best fit your post and your brand. “Hashtags for the sake of hashtags is definitely not a successful strategy,” Christy Stevens said. “It’s important to select hashtags that will help your post build a successful base and launch it into a higher sphere of influence.” Don’t Forget the Video While still images are the primary way of succeeding on Instagram, it’s important to branch out into the company’s other posting avenues – Instagram Stories and IGTV. Both video products have gained traction over the past 18 months and are expected to continue to gain market share against Instagram’s original still imagery news feed. Instagram Stories quickly outpaced Snapchat upon their launch and the allure of IGTV for videographers stems from its freeform use of video – with no time limits set by Instagram. For more information about the spr agency, please visit www.thespragency.com or call (480) 648-1770.Pages Tuesday, May 15, 2012 Biggest bust/improvement: Donruss Hey! It's Harold Reynolds again! This is not a repeat. This is post number 2,001. I republished this card both as a reminder to enter the contest and as a lead-in to my next judging fiesta, namely, figuring out the biggest improvement and bust in the history of Donruss. I don't think Donruss has as avid a following as the previous two brands we've compared, Topps and Upper Deck. I know I'm not crazy about many of the sets that Donruss produced over the years. My personal Donruss favorites are 1984 and 1985. Plus, 1981

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fare for accelerating technoculture & screaming memes, with a side order of strangeness and charm. Read articles and interviews which illuminate the New Edge culture. Warning:This site may contain unlabelled irreverence and subtle playfulness.Humorless and hypersensitive people should proceed with caution.TOMORROW'S TECHNOLOGY TODAY: Cell phones For the most part your cell phones do all the work...making calls, sending text messages, taking pictures. In Tomorrow's Technology Today Matt Stone shows us that the phone case is now being used to do some pretty cool stuff too.These are sound effects I have recorded for different projects that I am giving away. Check back as I add to the page often. Click on the description to download. I cannot predict your browser configuation so this will either make a page with a player or ask you where to save it. If it makes a player, right-click and choose "Save As... instead"A procession of 60 cars honking their horns and brandishing signs proclaiming “Free Them All” circled Bergen County Jail in Hackensack, New Jersey on March 27. A prisoner and guard in the jail had just tested positive for COVID-19, and the protesters were demanding that all nonviolent incarcerated people and ICE detainees be released in order to stop the spread of the virus and save thousands of lives. The protesters called it a “drive-by protest.” Since late March, similar actions involving hundreds of cars have taken place in other states as well, including Louisiana, Illinois and North Carolina. The protests are just one of the many creative tactics that organizers have been employing to show solidarity with the immigrant community while social distancing. Ambien Mitchell is an activist and educator working at New Sanctuary Coalition, a clinic that provides legal and emotional support for people navigating the immigration system. In her view, it has never been more critical to advocate for humane policy and demand accountability for those in power. “We’re living in a system of state violence, with decades of experience perpetuating incredible cruelty on vulnerable populations,” Mitchell said. “The state has already proven to have a blatant disregard for human life. And they’ve already proven that they believe some lives are less valuable than others.” “Every prison and every detention center is like a cruise ship that’s not allowed to dock.” Although the entire nation is grappling with the COVID-19 pandemic and its consquences, the undocumented community has been facing unique — and often overlooked — struggles. Those imprisoned in detention centers are kept in close quarters where social distancing is impossible. Economic relief plans such as the CARES Act neglect undocumented people altogether, though many undocumented workers are providing essential labor during this crisis and most undocumented people pay taxes. Meanwhile, despite the federal government’s own admission that the best thing that can be done to flatten the curve is to limit travel, deportations and ICE raids are still taking place. “It’s no secret that the undocumented community has been targeted and criminalized for decades,” said undocumented organizer Li Adorno, who works with the New Jersey chapter of the immigrant rights group Movimiento Cosecha. “Even in a crisis, the undocumented community is still being targeted. We’re always the ones that the government forgets about.” ‘Free them all’ Kathy O’Leary is the region coordinator for New Jersey at Pax Christi USA, a national Catholic peace and justice organization. In the past, she has helped compile reports on the desperate conditions plaguing New Jersey jails. Since the quarantine began, O’Leary has been pouring her energy into the fight for ICE detainees and prisoners to be released. In addition to organizing drive-by protests of detention centers in New Jersey, she’s also helped draft a petition calling on Gov. Phil Murphy to use his emergency powers to take action. “On a good day, getting access to health care when you’re in prison is completely at the mercy of the administration,” O’Leary said. “And a jail is not a sealed environment. Even though they cut off visitation, the guards still rotate three times a day and then go home to their families. The guards could very easily bring the virus back to the jail without knowing it — and if there is an outbreak in the jail, then that gets brought back to the community.” The petition is backed by over 30 social justice and immigrant rights organizations with chapters in New Jersey, including the Jewish Coalition for Refugees, the Sunrise Movement and Cosecha. “Even if all the petition does is elevate the issue — that’s important too,” O’Leary said. She considers the petition an opportunity to stand with incarcerated people across New Jersey who are going on hunger strike, demanding access to essentials like gloves, masks, soap and hand sanitizer. Skipping even a single meal in the dining hall of a detention center comes with the risk of being thrown in solitary confinement. Holding ICE accountable for their failures According to Ambien Mitchell of New Sanctuary Coalition, phone calls are another simple and remote option when it comes to advocating for undocumented people during the crisis. She suggests calling elected representatives because they can pressure ICE, as well as calling ICE field agents and detention centers themselves. “Every prison and every detention center is like a cruise ship that’s not allowed to dock,” Mitchell said. “And at this point, inaction has become an incredibly brutal and violent action. These aren’t fun conversations, but they’re conversations that are worth having — ICE is a federal agency, and we do pay their salaries with our tax dollars.” Adorno believes that ICE’s unwillingness to cease operations is not only putting detainees at risk, but the community at large. “Even during the pandemic, ICE continues to hunt down undocumented community members,” Adorno said. “In the past, ICE has claimed they would not go to school zones and courts — but then went against their own memos. That’s why the immigrant and undocumented community has very little faith in the local or federal government.” The impact of this mistrust is that even if they are experiencing symptoms, many undocumented people may hesitate to go to a hospital, despite ICE’s claim that they will not be arresting people who are seeking medical care. “Undocumented people don’t have health insurance, and they’re afraid to seek care at hospitals because ICE might go there,” Adorno said. “If you only have one member of the family who is working right now, and they get arrested, how is that going to impact the rest of their family?” Campaigns for commissary and worker relief First Friends is an organization of people who visit detained immigrants and asylum seekers in New York and New Jersey. Because of the crisis, their volunteers can no longer visit detention centers — so the organization has started a Gofundme to raise commissary money. Often, detainees can’t afford to buy the basics due to marked up prices and meager salaries that border on slave wages. “Commissary can be used to help incarcerated people feel a little more comfortable during this stressful time,” O’Leary said. “Buying an extra pack of ramen noodles or a candy bar can make them feel more human. But there are other things in there too — like soap and shampoo.” She noted that while inmates in places like New York are being used to produce thousands of gallons of hand sanitizer for less than a dollar an hour, they are not allowed to purchase sanitizer themselves because of the alcohol content. O’Leary also added that in addition to buying hygiene products, the crowdfunded commissary can also be used for phone calls to family, lawyers and friends — crucial connections to the outside world in a time when many inmates are lonelier and more isolated than ever. Also organizing to respond to financial need is Cosecha, a coalition of undocumented people and allies who have previously won fights like driver’s licenses for all in New Jersey. “Undocumented communities have always joined together to surpass tough times like this,” Adorno said, who is currently quarantined with Cosecha members and developing strategies for relief. “In our home countries, we don’t have a lot of help. The mutual aid we’re seeing rise up — this is the kind of thing that the undocumented community thrives at. We’re good at this because we’ve had to do it in the past. Nobody else is going to come rescue us.” Since the pandemic began, immigrants rights groups like Cosecha have been mobilizing to create relief funds for the undocumented community. (WNV/Loretta Graceffo) Because of their legal status, undocumented workers don’t have access to necessities like health insurance, paid sick leave, unemployment and other forms of government relief. In order to help ease the burden, Cosecha has started a fund to help families with needs like food, rent and utilities during the crisis. “You can’t feed a movement with service,” Adorno said. “You have to feed a movement by bringing people together. This fund has to be accompanied by organizing efforts. Otherwise it’s going to be really hard to sustain it.” Since the pandemic, Cosecha has begun training organizers through video conferences — and shifted its focus towards pushing for economic measures that will elevate undocumented and working class people, like popularizing the idea of a rent strike. The future of the immigrant rights movement COVID-19 is a health crisis of epic proportions, and its effects on the undocumented community have been devastating in ways that most Americans will never experience. At the same time, the pandemic has produced opportunities to mobilize and opened the door to conversations about

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app1-cancers-10-00031){ref-type="app"}. 3.13. Statistical Analysis {#sec3dot13-cancers-10-00031} -------------------------- Statistical differences between controls and drug-treated cells were determined by one-way ANOVA (Sidak). *p*-values \< 0.05 were considered statistically significant. Data were analyzed using the Stata 8.2/SE package (StataCorp LP, College Station, TX, USA). 4. Conclusions {#sec4-cancers-10-00031} ============== It is well established that drug tolerance is one of the key challenges for dual PI3K--mTOR inhibitors as NVP-BEZ235, which explains the slow progress of research and development of these inhibitors. Currently, only eleven new dual PI3K--mTOR inhibitors, including NVP-BEZ235, are being evaluated actively in the clinical stage, is currently in phase I/II clinical trials for advanced solid tumors (ClinicaTrials.gov, U.S. National Institutes of Health, Bethesda, MD, USA: <http://clinicaltrials.gov>), but none has been approved by the FDA. Although significant therapeutic effects against cancer have been demonstrated, NVP-BEZ235 have shown significant toxicity, including stomatitis, noninfectious pneumonitis, rash, hyperglycemia, and immunosuppression. Encapsulation strategy offers a potential approach for enhancing the solubility of NVP-BEZ235 improving its bioavailability and suggests the potential use of this formulation for oral administration. Oral administration would allow outpatient treatment, improving quality of life and reducing treatment costs. Cytosolic delivery strategies could contribute to simplify the entry or export of various cargo that are insufficiently permeable to plasma membrane. In this work we proposed an engineered system, based on CaCO~3~, to deliver NVP-BEZ235. Because of their central role in the initiation and progression of tumors, blockade of the mTOR and PI3K signaling pathways has emerged as a compelling target for the development of novel drug formulations for maximal therapeutic efficacy in many tumors. Taken together, it appears that dual PI3K/mTOR inhibitors, such as NVP-BEZ235, are required. Because of its intrinsic chemical hydrophobicity, NVP-BEZ235 is poorly tolerable from patients and negatively influenced the clinical studies \[[@B27-cancers-10-00031]\]. Its toxicity profile causes high percentage of adverse events leading to frequent discontinuation treatments. Despite these problems NVP-BEZ235 remains an attractive agent. Therefore, in order to overcome its chemical limitations, it is necessary to either reduce the administered dose or combining the efficacy of this molecule with other drugs for a synergic action. In view of its potentiality, and on the other side of its limitations, we focused this work on finding a nanotechnological strategy to achieve higher efficacy of the drug toward cancer cells, decreasing drug concentration and increasing drug penetration. Hence, we developed at first a promising payload drug delivery system based on CaCO~3~ NCs that improved the water solubility of NVP-BEZ235 making it immediately available to cell machinery. Furthermore, a new highly sensitive analytical method methods have been used to determine, qualitatively or quantitatively, whether NVP-BEZ235 has successfully traversed the cell membrane. The obtained nano-formulation has a cytosolic localization more efficient (almost 30%) than the free drug as demonstrated in the quantification analysis of NVP-BEZ235 in the intracellular fraction. This result is affected in a cytotoxic effect almost 50 times higher than free drug at the same nominal concentration, in T-cell lymphoma line, as well as in the phosphorylation of proteins involved in the mTOR pathway, as demonstrated in the western blot analysis. These overall results show that the fabrication of loaded NVP-BEZ235 CaCO~3~ nanocrystals is a promising drug delivery system able to improve the pharmacokinetics of this drug. Progetto "Tecnologie Abilitanti per Produzioni Agroalimentari Sicure e Sostenibili" (T.A.P.A.S.S)---"Cluster Tecnologici Regionali 2014". Codice regionale progetto PELM994 (CUP B38C14002040008). "FuturelnResearch" APQ Ricerca Regione Puglia---Programma regionale a sostegno della specializzazione intelligente e della sostenibilità sociale ed ambientale. PRIN 2010--2011 (D.M. 1152/ric del 27/12/2011) Nanotecnologie molecolari per il rilascio controllato di farmaci/NANO Molecular tEchnologies for Drug delivery NANOMED prot. 2010FPTBSH, CUP: F81J12000380001 is gratefully acknowledged. Viviana Vergaro and Giuseppe Ciccarella conceived and designed the experiments; Monica Civallero and Maria Cosenza performed the biological experiments; Francesca Baldassarre analyzed all data experiments with statistical analysis; Cinzia Citti and Giuseppe Cannazza performed LC-MS/MS experiments and contributed to results and discussions; Francesco Paolo Fanizzi, Stefano Sacchi and Samantha Pozzi provided the reagents and materials and contributed to results and discussions. Viviana Vergaro and Monica Civallero wrote the paper. The authors declare no conflicts of interest. • Detection and quantification limits (sensitivity) Limit of quantification (LOQ) was defined as the concentration at which the quantifier transition of BEZ235 yielded a signal to noise ratio (S/N) of 10 and it was 1 μM in cell lysate. Limit of detection (LOD) in cell lysate was estimate based on 5:1 S/N and it was 0.5 μM. • Specificity Typical SRM chromatograms of BEZ235 and IS in cell lysate showed no interfering peaks from endogenous substances at the retention time of BEZ235 and IS. The chromatograms of blank cell lysate also had no interfering peaks at the retention times of BEZ235 and IS. The specificity results indicate that the method is highly selective for BEZ235 analysis. • Calibration curve and Linearity Calibration curves for BEZ235 were performed in cell lysates (1 to 100 μM). Five replicates were used to establish the linear calibration equation (y = mx + c) and analyzed using the ratio of analyte peak area over IS peak area after quantitative integration by Mass Hunter software. Linearity was measured as the coefficient of determination (R2) for five calibration replicates. The acceptance criteria for each back-calculated standard concentration were ±15% deviation from the nominal value except at LOQ, which was set at ±20%. Linearity was excellent in the range 1--100 μM with corresponding coefficient of determination R2 \> 0.998. • Accuracy and precision Intra-day accuracy and precision were assessed from five replicates of LOQ and QC concentration levels (low LQC, middle MQC and high HQC). Inter-day accuracy and precision were assessed on three triplicates for five-day analysis of the three QC concentration levels. Accuracy of the method was calculated as percent deviation based on the difference between the mean concentration found and the nominal concentration. The percent deviation should be within 15% of the actual value, except at the LOQ, where it should not deviate by more than 20%. Precision was evaluated as percentage coefficient of variation (%CV) of the mean concentration found. The precision determined at each concentration level should not exceed 15% of the CV, except for the LOQ, where it should not exceed 20% of the CV. The accuracy and precision data for cell lysate. The intra-day accuracy showed percent deviation ranging from −1.19 to 4.22% with a %CV from 0.88 to 4.65%. The inter-day accuracy and precision showed percent of deviation ranged from to −3.80 to 8.50% with a %CV from 2.09 to 8.78. Since the accuracy and precision values were found within the acceptance limits, these results suggested that the method is accurate and precise. • Recovery The extraction recovery of BEZ235 was determined at the LQC, MQC and HQC levels by comparing the peak areas of BEZ235 extracted from spiked cell lysate samples prepared by spiking BEZ235 in blank cell lysate with the corresponding concentration of authentic standard solutions. Experiments were performed in five replicates. The extent of recovery should be consistent, precise and reproducible. The recovery of extraction of BEZ235 from cell lysate was \>82%. • Matrix effect The matrix effect was evaluated by determining the matrix factor (MF) and the IS-normalized MF from cell lysate. The determination was performed at the LQC, MQC and HQC levels in triplicate. The MF of BEZ235 was calculated by comparing the peak area of BEZ235 extracted from samples prepared by spiking BEZ235 in cell lysate with the corresponding concentration of the authentic solution of BEZ235 prepared in mobile phase. The MF of IS was determined and calculated in a similar manner. The IS-normalized MF is the ratio between the MF of BEZ235 and that of IS. The %CV of the IS-normalized MF from blank cell lysate should not exceed 15%. The %CV of IS-normalized MF in cell lysate was \<10%. The %CV \< 15% suggests that ion suppression or enhancement from cell lysate matrix is negligible in the assay. • Stability Stock solutions of BEZ235 and IS were checked for short-term stability

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Here he glanced at Neth'Gore quickly before continuing. "As I said, a few of these human people had advanced capability, they were natural channels. I am sure had they been T'Iea then they would have been quickly taken up and sent to Ter'Hadsnefel to learn how to temper and control their natural ability, taught the arts and ways of our T'Iea mages. To leave them untrained would have been dangerous, both to themselves and to others. Stories abound of such humans destroying great swathes of the land either by miss use of the arcane or by un-tempered ability. As a result many who exhibited these traits, if discovered, where cast out to live solitary lives far from others of their kind, for the humans had a deep mistrust of them. Some of these unfortunate people were even ritually burned if they were thought to have misused their traits and un-tempered skill. Anyway, many of us were assigned to stay amongst these humans and help where we could. But Te'Onolan'u'De'Hu'uinned increasingly demanded restraint. Some of us helped more than we should perhaps, for his orders were not to interfere. " As before Orln turned and gazed at Neth'Gore's back for a few seconds. Thor waited for Neth'Gore to say something for it seemed that Orln was inviting him to do so, but the mage remained with his back turned to them, toying with his gear. Orln carried on with his explanation. "On returning from one such trip we learnt that the goblins had invaded our encampment, probably looking for food or an opportunity to thieve anything that they thought useful, or so we were told by others in the legion. The goblins were easily held off and sent running, for they were not many, and their attack was disorganised and uncoordinated with no real strategy or pre-planning. But Te'Onolan'u'De'Hu'uinned seemed to bare a strange hatred towards them and he ordered his guards to pursue the goblins, hunt them down and kill them. He said this would act as a deterrent to others. We were appalled to hear such an order for that is not our way of course. My understanding was that we should lay low and explore, our orders were to watch for T'Iea'Neat'Thegoran activity not to take grim revenge upon a lesser race. Over the next few months, Te'Onolan'u'De'Hu'uinned seemed to change, his attitude grew more grave. He became insular, guarded and thoughtful, quick to anger. He ordered small unprovoked skirmishes into the goblin lands to attack their encampments and destroy the goblin infrastructure, burning any encampments that were found, hunting them down and killing them even fowling water sources known to be used by them. Many in the legion could not understand this, many sought to dissuade the command chain of the legion. Those that felt this way became organised and approached Te'Onolan'u'De'Hu'uinned in an attempt to discover why he felt such hatred for the goblins, alas these soldiers we never saw again. We were told they had been killed in a skirmish. But this we did not believe for the goblins were disorganised and had primitive weapons and little skill in wielding what they had, they could not overcome the skill of our soldiers unless by pure luck they overcame an individual by sheer numbers. So the persecution of the Goblin men continued. We knew this was not the way of the T'Iea legions, never have we sought to be such an aggressor, especially upon a far weaker force. We couldn't believe that soldiers we knew so well could break that code of training and reduce themselves to such actions. But because of this systematic policy of genocide the goblin men learnt to fear and hate us. One day Te'Onolan'u'De'Hu'uinned announced that his sources had discovered what he thought to be the main centre of population of the goblin men, he was planning an all-out attack to teach them a lesson, "once and for all we will settle the goblin problem," he said. We were deeply shocked and many complained to Te'Onolan'u'De'Hu'uinned that this was not what we had been sent here for. Te'Onolan'u'De'Hu'uinned flew into a rage; he ordered the imprisonment of many that he saw opposing him. One such was the swordsman of our Trete'Y'Thego, he was taken from us and we have not seen him since. The raid on the goblins went ahead." Here Orln lowered his head into his hands and sighed, "it was inevitable, the goblin forces were wiped out, but not content with his victory, Te'Onolan'u'De'Hu'uinned ordered the complete burning of all the lands surrounding the encampment and the systematic murder of all goblins found. Both I and Neth'Gore were sickened to the core at this despicable act. We would have no part in it for it is one thing to fight another armed warrior, but quite a different thing to kill in cold blood the elderly and the innocent, the females and their whelps." Thor could not believe what he was hearing; this was not something that he expected. The T'Iea legions had strict codes of honour and behaviour towards the enemy forces and especially towards the innocent and to civilians. To break these codes would be unimaginable, a heinous crime against the oppressed but also against the legion itself. The expression upon his face must have given him away for Orln then said, "I see by your face that you are abhorred with this story. Then perhaps you would have done the same as myself and Neth'Gore and others. We deserted, we returned back to Ter'Hadsnefel, we gave ourselves up as deserters and we told our story in the court of the generals. Well to cut a long story short, we were divested of our rank and denied any further active duty in the legion whilst our final fate was decided. But thank the Maker, to our honour one general was on our side he fought for our case and even though he did not change the final verdict of dishonourable dismissal from the ranks he did manage to keep us from imprisonment and take on responsibility for us. That general even though he risked much, made sure that we remained trained and able minded over the period of time we were with him. We do not know even today why he took this action. But we are thankful to him for his mercy." Thor thought for a while and said, "that general, the one who showed you mercy, I guess that he was The lady Solin's friend, Te'Onolan'u'De'Yiun?" "Yes," was the simple answer. Thor just nodded slowly in response. "Alright gentlemen, I thank you for your frankness and trust. It is a sorry tale with more than a few surprises. I do not know what we may find there in the east, but we are tasked with this and I intend that we carry out our orders to the best of our capability. We leave in the morning, I suggest you say your farewells and make good any outstanding business. We have a long journey ahead of us, as you well know. I will be grateful for your knowledge and experience to get us to our destination swiftly and safely." ## Chapter 18. First Class to Gwéldølĩn That evening Nar'Allia found herself walking through the wide streets of Scienocropolis. She was being escorted to the airship that was waiting to transport the Pnook emissary and herself to Gwéldølĩn. She found herself travelling through a very prosperous looking part of the Pnook city accompanied by two Pnook guards, a personal escort of honour sent by the Pnook King himself. She looked up at the buildings that surrounded her. Tall, angular edifices, reaching high enough to scrape the sky, if she looked upwards for too long she found herself experiencing a sensation of falling, of losing her balance, it seemed like the building were tilting over above her, almost falling over to crush her. She shook her head. She wondered at the buildings being pointed out to her by the two escorts, the various purposes and uses to which they adhered, many of which Nar'Allia did not understand. Nar'Allia was in no doubt that the city may appear beautiful to some, in deed she could see herself that it possessed a certain attraction, yet it was so very different from her home. T'Iea cities had an architectural emphasis linked to the natural world, an organic component that defined their character. But here, there was nothing natural; it was totally a creation of the Pnook, without any naturalistic component whatsoever. But then the Rust Desert did not offer much in the way of natural beauty, at least not as she would describe. She had to admit she did find this a little unsettling. The buildings perhaps did have a certain beauty about them yet she found them also to be hard and sterile. As she walked her mind wandered, she found her curiosity rising within her as to whom this emissary of the King may be, she had neither met the King or his emissary as yet. Her escorts had been sent with a sealed note. She

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on two allegations of Defendants' violation of the ESA's consultation requirements. First, Plaintiffs argue that the biological opinion relied upon by Defendants in conducting their training exercises was issued to Defendants by the United States Fish and Wildlife Service ("FWS") without Defendants having first submitted to the FWS the required biological assessment. Before delving into this claim, the Court shall address the standard to be applied to the FWS' issuance of the biological opinion. Defendants allege that Plaintiffs failed to comply with the ESA's requirement that a Plaintiff provide Defendants with notice of suit 60 days before filing. Plaintiffs counter with the letter that they sent informing Defendants of their intent to sue based on Defendants' failure to prepare a biological assessment for the FWS. Because the Court finds, at least at this stage, that Plaintiffs complied with the notice requirement, the appropriate standard to apply is whether there has been a "violation" of the ESA under its citizen suit provision, 16 U.S.C. § 1540(g), rather than whether there has been "arbitrary and capricious final agency action" under the Administrative Procedures Act ("APA"), 5 U.S.C. § 706.[4] Thus, the Court must decide whether Plaintiffs are likely to succeed on the merits of a claim of a violation of the ESA's requirement of the preparation of a biological assessment before the issuance of a biological opinion. Defendants counter Plaintiffs' argument by asserting, among other things,[5] that the consultation *159 package prepared by Defendants and submitted to the FWS was an acceptable substitute for a biological assessment. In support of this argument, Defendants point out that the purpose of a biological assessment "is to evaluate the potential effects of the action on listed or proposed species or designated or proposed critical habitat and determine whether any such species and habitat are likely to be adversely affected by the action." Further, under the relevant regulations, the contents of a biological assessment are chosen at the discretion of the agency seeking the biological opinion. See 50 C.F.R. § 402.12 (2001). The biological assessment, according to Defendants, need only be adequate to "serve as an analytical instrument" that can be used for analyzing the effects of the agency's action. Plaintiffs essentially agree with this characterization of the purpose of a biological assessment, but they argue that the consultation package that Defendants substituted for a biological assessment was not adequate to fulfill the purpose of a biological assessment. In support of the sufficiency of their consultation package as a biological assessment, Defendants assert that the package (1) "evaluated the potential effects of the training activities on listed species and critical habitat and determined whether any such species and habitat were likely to be adversely affected by the action;" (2) "contained the results of the on-site inspections and monitoring of the site;" and (3) "considered the views of the [FWS'] Boqueron Field Office biologists during informal consultation with the [FWS]." According to Defendants, these aspects of the consultation package were "consistent with the framework in the regulations describing the recommended contents of a biological assessment. See 50 C.F.R. § 402.12(f)." Plaintiffs, on the other hand, argue that Defendants' consultation package was not an adequate substitute for a biological assessment. In support of their contention. Plaintiffs assert that the consultation package does not contain "the results of on-site inspections, the views of recognized experts, a review of the literature, an analysis of the effects of the action on listed species or an analysis of alternate actions." This assertion is inadequate to impugn the sufficiency of Defendants' consultation package for two reasons. First, the contents of a biological assessment are discretionary with the agency that prepares it; the regulation governing the contents of a biological assessment lists items that it "may" contain. See 50 C.F.R. § 402.12(f) (2001).[6] Second, even if the items that Plaintiffs list were required, Defendants' consultation package goes a considerable way toward satisfying those requirements. The consultation package, Dkt. No. 12, Exhibit 22, provides a list of endangered and threatened species in the training area, descriptions of the species' habitats and nesting areas, reasons for the species' decline, actions taken to protect the species, results of aerial surveys, and a list of restrictions on military exercises. The Court finds at this preliminary stage that Plaintiffs are not likely to succeed *160 on the merits of a claim of a violation of the ESA's requirement of the preparation of a biological assessment. In other words, Defendants' consultation package is likely to be found to satisfy the requirement of a biological assessment. Plaintiffs' second claim of violation of the ESA's consultation requirements is that the biological opinion issued by the FWS suffers from substantive defects that make its issuance arbitrary and capricious under the APA.[7] The Court shall address these alleged defects in turn. First, Plaintiffs assert that the FWS' biological opinion "fails to consider several cumulative effects on the listed species," including the effects of sonar and "sonobuoys" on listed species. In response, Defendants argue that the FWS "did analyze the overall impacts to the species and the habitat." Defendants counter that the concept of "cumulative effects" refers to the effects of State or private activities in the area and that the FWS did not analyze these effects because it anticipated no such activities. Second, Plaintiffs contend that the FWS' biological opinion failed to the effects on listed species of inert munitions "skipping" off of targets and into the water. Defendants respond that their consultation package adequately addressed skipping and that the FWS determined "that rounds skipping into the water were not likely to adversely affect any listed species." Third, Plaintiffs claim that the biological opinion "fails to mention nighttime firing as a factor that might adversely affected listed species. The biological opinion simply states that the `use of illumination rounds will be minimized to the extent practicable.'" Defendants reply that although the biological opinion does not discuss nighttime firing at length, the consultation package on the basis of which the biological opinion was issued goes into considerable detail regarding the measures that Defendants will take to minimize the impact of nighttime firing on species in the area. Fourth, Plaintiffs contend without support that the FWS failed to use the best available commercial and scientific data in rendering its biological opinion. Defendants counter by stating that the FWS' determinations "are based upon the best available data and consideration of relevant factors." Fifth, Plaintiffs assert that the FWS' biological opinion ignores "the potential impact that mitigation measures such as beach grading and crater filling may have on sea turtle hatchlings." Defendants respond that the biological opinion does consider these issues. The biological opinion states, [i]n the unlikely event that a round/bomb does hit the beach, craters and materials that may affect the ability of nesting or hatching turtles to traverse the beach will be filled and removed to ensure that neither female sea turtles or [sic] their offspring will be trapped. Additionally, any vehicle tracks/ruts running parallel to the amphibious beaches will be removed (i.e. graded) so there will be no impact to turtle hatchlings. Dkt. No. 12, Exhibit 24. Thus, far from ignoring the effect of mitigation measures on sea turtle hatchlings, the FWS' biological opinion discusses mitigation measures as a means of protecting turtle hatchlings. Sixth, Plaintiffs claim that the biological opinion contains insufficient discussion of *161 the plight of the brown pelican. Defendants retort with examples of attempts they have made to accommodate the brown pelican and point out that the biological opinion requires a 1,500-foot minimum altitude for flights, as opposed to the previous 500-foot restriction, for the protection of the brown pelican.[8] Seventh, Plaintiffs assert that the FWS' biological opinion ignores recent literature on "marine mammal and sea turtle survey methodology." Proper consideration of this issue, Plaintiffs aver, would have made clear to the FWS that sea turtle and marine mammal survey flights could be more effectively conducted at times other than those proposed in the biological opinion. Finally, Plaintiffs state that the FWS' biological opinion fails to consider the effect of "acoustic and vibration disturbances" on sea turtles and contains "many substantive and statistical inaccuracies." Plaintiffs offer insufficient evidence in support of these last arguments. It is far from clear, at this preliminary stage, that the FWS' biological opinion suffers from the numerous defects which Plaintiffs attribute to it, much less that these defects satisfy the exacting requirement of rendering the opinion "arbitrary and capricious." Both parties make strong arguments regarding these alleged defects that are in stark opposition. The Court is loathe to substitute its judgment for that of the FWS, especially when under the APA the actions of the FWS need only avoid being found "arbitrary and capricious."[9]See United States v. Hernandez, 979 F.Supp. 70, 76 (D.P.R.1997) (pointing out that "[i]f the agency considered the relevant factors and if the agency did not make a clear error of judgment, then the decision was not arbitrary or capricious"), aff'd, 187 F.3d 623, 1998 WL 1085772 (1st Cir.1998). Thus, the Court finds that Plaintiffs are not likely to succeed on the merits in showing the FWS' biological opinion to be arbitrary and capricious under the APA. 2. Potential for Irreparable Harm Plaintiffs argue that without a preliminary injunction they will suffer two types of irreparable harm. First, they assert that a procedural violation of the ESA's consultation requirements automatically constitutes irreparable harm. Second, they cite the potential for harm to listed species in the event that Defendants' training exercises continue. Plaintiffs state, "[t]he death of even a single member of an endangered species represents irreparable harm since it interferes with breeding opportunities and eliminates genetic material in a diminishing gene pool." Defendants dispute

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, for Appellees. Unpublished opinions are not binding precedent in this circuit. See Local Rule 36(c). 3 PER CURIAM: Appellants appeal from the district court’s order denying relief on their 42 U.S.C. § 1983 (1994) complaint. We have reviewed the record and the district court’s opinion and find no reversible error. Accordingly, we affirm on the reasoning of the district court. Minns v. Spore, No. CA-96-512 (E.D. Va. Jan. 23, 1998). We dispense with oral argument because the facts and legal contentions are adequately presented in the materials before the court and argument would not aid the decisional process. AFFIRMED 4 Carol Crawford Carol Ann Crawford (February 22, 1934 – August 10, 1982), also known as Carol Stolkin and Carol Ross, was an American backgammon and bridge player from Buffalo, New York who spent many years in Detroit, Michigan. In 1973, she became the second woman to win the world backgammon championships. She was the second wife of John R. Crawford. Like her husband, she had talent in both backgammon and bridge. Bridge accomplishments Wins Runners-up North American Bridge Championships (3) Chicago Mixed Board-a-Match (2) 1974, 1975 Smith Life Master Women's Pairs (1) 1976 References External links Category:American backgammon players Category:American contract bridge players Category:1982 deaths Category:1934 births Category:Sportspeople from New York City Category:People from Wilmette, Illinois1. Introduction =============== Although concrete is the most commonly used construction material anywhere in the world, it is not considered sustainable because of its destructive nature in the consumption of natural resources and the environmental impact after its use. Approximately 65% of the volume of concrete is aggregate; therefore discovering suitable substitutes for natural aggregates is a priority. By this way, for the construction industry, reusing concrete waste may be an attractive option for the good practice of producing high quality eco-concrete \[[@B1-materials-08-04457]\]. The objective is to integrate environmental aspects into the product design in order to improve its environmental performance throughout its entire life cycle, and in particular its duration and residual treatment \[[@B2-materials-08-04457]\]. Concrete's thermal behavior is relevant to any of its applications, especially in structural concrete where it is ideal to have low thermal conductivity, dimensional stability, high specific heat and little or no decrease in strength with increasing temperature. Research is based on three pillars: use of concrete RAs; analysis of thermal conductivity, as the main parameter to measure energy efficiency; and the use of IRT as a qualitative, non-destructive technique for the study of thermal behavior. The importance of the study lies in the scarce research on thermal properties of this type of concrete, self-compacting with RAs, and validation of thermography as a first approach to the study of thermal conductivity, quantifying the results through a heat flow meter. The current state of the research and publications in the three key areas of research is reviewed below. 1.1. Background of Recycled Aggregate ------------------------------------- With the clear objective of prevention, the Directive 2008/98/EC establishes the legal framework for the treatment of one of the main current environmental problems such as the generation and management of waste from different industries, promoting reuse, and recycling. This Directive has been transposed to the different member states of the European Union, which in Spain was materialized in the current 2014--2020 State Program for Waste Reduction with the aim of reducing 10% of the waste generated in 2010 by 2020. The main product of construction and demolition wastes recovery is the RA, granular material resulting from the treatment of inorganic materials previously used in the construction. Any facility that gives exclusive service to the construction work is considered an integral part of it, including precast concrete plants, among others. The need to reduce the final amount of waste produced in plants of precast concrete, with the intention of using it as RA in new parts manufacturing, thereby reducing the consumption of natural aggregates, is the target for energy efficiency this article is based on. Construction and demolition wastes have been subject of study of many researchers in recent years. Behera *et al.* \[[@B3-materials-08-04457]\] have conducted a thorough review of the main results, ranging from the process of obtaining the RA; the analysis of the physical and chemical properties of the different types of RAs; analyzing the properties of recycled concrete both fresh and hardened state; and various techniques to improve the properties of RA, as well as the main issues on its use. Out of the three RA types according to their origin (concrete, ceramic or mixed), recycled concrete aggregates object of this study may have two origins: traces of manufacturing (production disposed elements and tested specimens), or demolition of concrete structures. While in the first case the aggregates are relatively clean, with only cement paste attached; in the second case, the aggregate is often contaminated with salts, bricks and tiles, sand, dust, wood, plastic, cardboard, paper, and metals \[[@B4-materials-08-04457]\]. There are few countries that have regulations or recommendations of use for this type of aggregate for structural concrete, finding different trends in the required quality of RA, of the maximum allowed content in concrete, or limitation on its applications. Rilem \[[@B5-materials-08-04457]\], one of the first to be developed, and adopted in other countries such as Belgium or Hong Kong, pioneers in this field, allows the use of RAs with maximum absorption of 10% in concrete with category resistant to 50 N/mm^2^. The Japanese standard \[[@B6-materials-08-04457]\] is more stringent and fixes maximum absorption at 7% for concretes of category resistant up to 24 N/mm^2^, although the most demanding of all is the Spanish regulation EHE-08 \[[@B7-materials-08-04457]\], based on concrete made with coarse recycled aggregate from the crushing of concrete waste. The required characteristics for RA's concrete according to the EHE-08 that most affect this research are: Aggregates from concrete.Coarse aggregate with absorption \<7%.Banned in precast concrete.Minimum aggregate size 4 mm.Replacement of natural aggregate by RA, maximum recommended 20%.Strength limit of 40 N/mm^2^. This project focuses on the aggregate from crushing concrete pieces, which does not comply with quality control in a precast concrete plant in Galicia (Spain). It is reported that the recycled aggregates are relatively weaker than the natural ones, and therefore, compositional differences can be significant depending on the proportion of mortar present in the residue, which is the origin of the worst features of RAs, such as low density, low conductivity, and increased water absorption, Los Angeles coefficient of abrasion, and sulfate content. These characteristics also affect adversely the quality of the recycled concrete related elasticity, shrinkage and creep, as well as durability. The expected properties of recycled concrete with RAs from concrete waste are \[[@B8-materials-08-04457],[@B9-materials-08-04457],[@B10-materials-08-04457],[@B11-materials-08-04457],[@B12-materials-08-04457]\]: Water demand in the fresh recycled concrete is higher than that of fresh concrete made by natural gravel and cement consumption for the same strength is somewhat higher.Recycled concrete density is lower than that of the original concrete; with 100% replacement of coarse aggregate, a density between 10% and 20% lower can be obtained.Substitutions of up to 30% of the conventional aggregate by RA do not significantly alter the compressive strength of the new concrete. When 100% of the coarse aggregate is replaced, the compressive strength may decrease between 10% and 20%.The elasticity module of recycled concrete is always lower (between 15% and 40%) than the reference concrete and reaches even smaller values when recycled fine aggregate is also used.The shrinkage and creep of recycled concrete are maintained when coarse aggregate replacement is less than 20%, whereas with a 100% replacement of coarse aggregate, shrinkage can increase up to 50% and creep between 30% and 60%. If fine recycled aggregate is also used, both values increase even more.For the same dosage, both absorption and porosity of recycled concrete increase. In reference concrete having 5%--6% absorption and 11%--13% porosity, absorption and porosity values between 8%--9% and 16%--20%, respectively, might be achieved. The properties that may in principle be a problem, such as low density and high porosity, in this project are considered an advantage when designing elements aimed at, among others, serving as thermal insulator. It would be worth mentioning, in view of highlighting possible concrete solutions with enhanced eco-friendly features, the possible role of fly ash in concrete with recycled aggregates, in terms of both mechanical performance \[[@B13-materials-08-04457]\] and thermal properties \[[@B14-materials-08-04457]\]. 1.2. Background on Thermal Conductivity of Concrete --------------------------------------------------- Different studies show that the three most influential factors in conductivity are the aggregate type, porosity and moisture. The factor that most affects is the type of aggregate used in its manufacture. If aggregate has higher conductivity, the concrete will also have higher conductivity. The thermal conductivity of natural aggregates is between 1.163 and 8.6 W/mK \[[@B

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-based Tailwind was to receive over the term of the deal: $6.1 million in 2001; $7.61 million in 2002; $8.23 million in 2003; and $8.66 million in 2004, plus a total of $400,000 for a junior program. About $700,000 more was added to the deal through contract modifications, which included adding $75,000 for "promotional activities." The 2003 audit conducted by the USPS Inspector General faulted officials for "ineffectively" managing extras, such as event tickets and invitations. "Over the years, many different sponsors have seen -- and continue to see -- the benefits of associating with Lance and his cycling teams," Armstrong spokesman Mark Fabiani said in a statement to The Associated Press. Jim Andrews, a sponsorship expert with the Chicago-based consulting firm IEG, says that this is the first time USPS has publicly acknowledged the specifics of its sponsorship deal, which he calls "very significant, and not standard, but also not unheard of for a top-flight team." The escalating figures show the tangible effect of Armstrong's star power and the leverage it gave Tailwind. The agency's initial contract with the team in 1996 was for $1 million. Armstrong signed with the team before the 1998 season, and won the first of his record seven Tour de France titles in 1999. By 2000, the contract, renewed yearly, had grown to $3.3 million. In 2004, it was more than eight times the original amount. The documents also show the vast discrepancy in bonus payments. An invoice from August 2001 shows Armstrong earned $1.47 million for stage wins, days wearing the leader's yellow jersey and the overall win at that year's Tour. Teammate Tyler Hamilton, whose contract stipulated that he would be the second-highest paid rider after Armstrong, earned just $150,000 in bonuses for the same race. Hamilton, who retired in 2009 after admitting to a second doping offense, testified under subpoena before a federal grand jury that is meeting behind closed doors in Los Angeles. The specific dollar figures revealed in the documents are relevant to more than just that criminal investigation, which began with an inquiry into another American cycling team but ramped up when former Postal rider Floyd Landis confessed to his own use of performance-enhancing drugs and described organized doping on the team. Sources have confirmed to ESPN that Landis, Armstrong's teammate from 2002 to 2004, filed a federal whistleblower lawsuit last spring at about the same time that he made those allegations. The Department of Justice is weighing whether to intervene on Landis' behalf, a move that would greatly increase his odds of success. Plaintiffs are eligible for up to a third of the treble damages that prosecutors can assess if they prove government funds were fraudulently used. Armstrong strongly denies that he ever doped, and ex-aides such as the team's former medical director, Luis Garcia del Moral, have backed him, saying they never saw anything untoward. USPS officials also maintained they had no knowledge of doping on the team. Yet the newly released Postal Service documents show that, as early as 2000, officials were becoming queasy about news stories tying the team to drugs. The four-year renewal struck that year included a "morals turpitude and drug clause," specifically citing "failure to pass drug or medical tests" and "inappropriate drug conduct prejudicial to the team" as causes to suspend or fire riders. Excerpt from "morals" clause. (Click to view entire document) The renewal also included a negative publicity clause that became an issue when a French television crew found suspicious medical waste in trash disposed of by team staff members. The French government subsequently launched an investigation into the team but closed the case two years later. In February 2001, Lynda Zelnick, a USPS contracting officer, wrote to Allen Furst, then the managing director of Tailwind, to warn him about the "the need for prudence and discretion in talking with the media." She also noted "the Postal Service's concern about the deleterious impact upon the anticipated value of our sponsorship" that the news was having, and said that the agency was hiring a PR firm to run interference in the future. The $50,000 cost, she added, was being deducted from the overall sponsorship fee. Andrews says he believes that there are several people with intimate knowledge of the deal who may be asked to come forward by federal investigators. "There's another shoe out there," he said. "I'm just not sure if it will drop. I'm not sure anyone else is going to break their silence." The reason originally cited by USPS for denying the public records request was that "publicizing the price needed to obtain sponsorship rights [would] harm [our] ability to negotiate cost-effective sponsorships" in the future. On the appeal, it was pointed out that the agency no longer maintains sports sponsorships, and any financial information is at least six years old. Shaun Assael is a senior writer for ESPN The Magazine. ESPN.com's Bonnie D. Ford contributed to this report."The officials at The Louvre have until the end of 1389 [the Iranian year ending March 2011] to precisely tell us when and what they are going to set up here," he added. Sensitivities over the French role in the excavation and export of Persian cultural artifacts are nothing new. Throughout the 19th and 20th centuries, France was granted a series of exclusive excavation concessions over important historical sites such as Susa, the capital of the Persian Empire under Cyrus the Great. According to those contracts, as many as half the artifacts found went to the French and many ended up in European private collections or museums. The dispute with the Louvre follows a similar controversy with the British Museum over the exhibition of the Cyrus Cylinder, an ancient clay cylinder with cuneiform script praising the lineage and deeds of Cyrus the Great. The British Museum delayed lending the cylinder to the National Museum of Iran after the disputed 2009 presidential elections and the upheaval that followed, citing security concerns, but Iranian authorities accused the British of playing politics. The controversy was eventually resolved and the cylinder went on display in Iran from September 2010 to January 2011. Photos, from top: The Louvre in Paris is accused by Iranian authorities of failing to live up to an agreement to exhibit artifacts in Iran; the Cyrus Cylinder was at the center of an earlier dispute between Iran and the British Museum. Credits: David Monniaux via Wikimedia Commons; Mike Peel via Wikimedia Commons.I finished the new season. I feel like they were really clicking at the end there, like the growing pains were starting to resolve -- they weren't trying to cram quite so many riffs in, and I could tell Baron and Jonah's voices apart. I'm interested in seeing where they go from here. Meanwhile, Rifftrax has its annual Kickstarter going; this year's live shows will be Space Mutiny and Krull. Kick in at $1 and you get at least two shorts; they'll add another one every 200 backers, up to 10. The episodes are still listed in a completely baffling and inexplicable order. It's not chronological, it's not based on popularity (Manos is in between Girl in Gold Boots and Catalina Caper), it doesn't alternate Joel-Mike-Joel-Mike, and it doesn't follow the order of the DVD releases, so my current working theory is that the episodes are sorted based on the "nobody gave a fuck" algorithm. Regardless, there's some good shit in there. And given that there are nearly 200 episodes in the original series, there are still a lot of them I haven't seen. And of course thanks to the constant churn of movie rights, the list of legally-available episodes is constantly in flux, so watch 'em while you can. (On the subject of not-legally-available episodes, has anyone ever managed to find a rip of the Godzilla vs. Megalon DVD? I've looked but I've only ever found crummy VHS rips. ...shit, I bet I've still got a VHS copy around here somewhere; I should see if mine's in any better shape than the digital copies I've seen up to this point. Same with Fire Maidens from Outer Space and anything else I've got that's not commercially available. I should really go through these tapes before they deteriorate completely.) 372 Pages We'll Never Get Back is basically a Rifftrax Book Club podcast, wherein Conor Lastowka and Mike Nelson read and discuss a book. Season 1 is Ready Player One. I've listened to the intro episode and Episode 1, and I think I'll stick with it even though I haven't read the book and have no intention of doing so. I think I'd probably get more out of it if I'd actually read it, but their summaries and excerpts are enough to follow along. I have also learned that my dog does not give a fuck when people on the car stereo say her name. The most important detail: they're tweaking the format somehow to be a better fit for Netflix and binge-watching; Joel hasn't shared the details except that it's only going to be 6 episodes this time around. New MST3K tour starts in October. Joel will be riffing alongside Jonah and the Bots. They're doing Deathstalker (the first one; M&tB did the third one back in

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ane Curl was originally committed to prison following a February 24, 1976, conviction for assault with a deadly weapon. (Pen. Code, § 245.) Under the Indeterminate Sentence Law (ISL), applicable at that time, the Adult Authority fixed his term at 20 years. On April 22, 1977, respondent committed and was subsequently convicted of the second degree murder of a fellow inmate while incarcerated at the California Medical Facility, Vacaville. (Pen. Code, § 187.) His ISL term was then set at five years to life, and this sentence was ordered to be served concurrently with the prior assault. After the passage of the determinate sentence law (DSL) (Pen. Code, § 1170 et seq.), respondent's term was recalculated under the DSL to be a concurrent term of six years pursuant to section 1170.2. Six months later, while serving the concurrent sentences at the state prison in Soledad, respondent stabbed two inmates. He pleaded guilty to assault with a deadly weapon (Pen. Code, § 4501) and was sentenced to the upper base term of four years, which was ordered to run consecutively to the terms he was presently serving. Relying on People v. McCart, supra, 32 Cal.3d 338, respondent petitioned the superior court for a writ of habeas corpus. He claimed that Penal Code section 1170.1, subdivision (c) requires that all subsequent terms for in-prison offenses which are ordered to be served consecutively be calculated at one-third of the middle base term as set forth in subdivision (a) of that section. Concluding that the situation in McCart was similar to the instant matter, the trial court granted the writ petition. In light of the difference discussed below, we read McCart to reject the calculation respondent espouses. *239 In People v. McCart, supra, 32 Cal.3d 338, the defendant was convicted of an offense while in prison and was sentenced to a consecutive six-year term. Two months later defendant was convicted of a second in-prison offense, possession of a deadly weapon by a prisoner (Pen. Code, § 4502), which the statute required to be served consecutively. The trial court imposed the full upper base term of four years to be served consecutively to the prior terms. The defendant, McCart, argued that former Penal Code section 1170.1, subdivision (b), renumbered as subdivision (c), required that the length of consecutive terms for multiple in-prison offenses be calculated according to the principal term/subordinate term formula contained in subdivision (a). (People v. McCart, supra, 32 Cal.3d at p. 341.) The Supreme Court agreed, rejecting the People's main argument that the statute reflected a legislative intent to provide full consecutive terms for in-prison offenses where the sentences are imposed in separate proceedings. (Ibid.) The People relied on the language of subdivision (c) which provided "`the term of imprisonment for all such convictions [which such person is required to serve consecutively] shall commence from the time such person would otherwise have been released from prison.'" (Id., at p. 342.) However, the court noted that this argument overlooked the last sentence of the section which read: "`The provisions of this subdivision shall be applicable in cases of convictions of more than one offense in different proceedings, and convictions of more than one offense in the same or different proceedings.'" (Id., at p. 343.) The court concluded that when these provisions were read together it called for "computation of a single term of imprisonment for all convictions of felonies committed in prison and sentenced consecutively, whether multiple convictions occur in the same court proceeding or in different proceedings." (Ibid., italics added.) All contemporaneous, or nearly contemporaneous, consecutive in-prison offenses are to be calculated in the same manner as for nonprison offenses. The instant matter differs from the facts in McCart in one important respect; here, respondent was sentenced to only one consecutive term for his second in-prison offense, not two as in McCart. Penal Code section 1170.1, subdivision (c) reads as follows: "In the case of any person convicted of one or more felonies committed while such person is confined in a state prison, or is subject to reimprisonment for escape from such custody and the law either requires the terms to be served consecutively or the court imposes consecutive terms, the term of imprisonment *240 for all such convictions which such person is required to serve consecutively shall commence from the time such person would otherwise have been released from prison. If the new offenses are consecutive with each other, the principal and subordinate terms shall be calculated as provided in subdivision (a), except that the total of subordinate terms may exceed five years. The provisions of this subdivision shall be applicable in cases of convictions of more than one offense in different proceedings, and convictions of more than one offense in the same or different proceedings." (Italics added.) Giving effect to all the language in the statute (Gay Law Students Assn. v. Pacific Tel. & Tel. Co. (1979) 24 Cal.3d 458, 478 [156 Cal. Rptr. 14, 595 P.2d 592]), it seems clear that the Legislature intended that in-prison offenses, sentenced consecutively, should begin to run from the expiration of the prior term. As applied to the instant matter, the prior term reflects respondent's concurrent sentences for assault with a deadly weapon and second degree murder. It is the Legislature's intention to standardize only those in-prison offenses which are sentenced consecutively. Since respondent received a concurrent sentence for his first in-prison crime of murder, he was not prejudiced and does not fall within the harmonizing purpose of the statute. This reading is consistent with the interpretation of the statute given by the McCart court: "Read together these provisions call for computation of a single term of imprisonment for all convictions of felonies committed in prison and sentenced consecutively, whether multiple convictions occur in the same court proceeding or in different proceedings. That this term is to commence when the person would otherwise have been released emphasizes that the new term is to be fully consecutive to the term already being served: i.e., that it must commence at the end of the longest of the prisoner's previously imposed terms. [Fn. omitted.]" (People v. McCart, supra, 32 Cal.3d at p. 343, italics added.) Applying the foregoing rationale to the instant matter, it seems clear that the first consecutively sentenced in-prison offense; i.e., assault, is to be a full term which commences at the end of respondent's concurrent term. Accordingly, it was error to reduce the sentence for the in-prison assault to one-third of the middle base term; i.e., one year, instead of the four-year principal term originally imposed. (2) The People next argue that section 1170.1, subdivision (c) does not apply here since the in-prison offenses were committed in different counties. We disagree. Although the murder was committed while Curl was incarcerated at the California Medical Facility in Vacaville, Solano County, and *241 the more recent assault with a deadly weapon was committed while Curl was confined to the state prison in Soledad, Monterey County, it is irrelevant, as the McCart court pointed out, whether the convictions occurred in the same court proceeding or in different proceedings. (People v. McCart, supra, 32 Cal.3d at p. 343.) Likewise, the overriding purpose of uniformity and proportionality in prison terms would not be achieved if such terms were determined by the respondent's fortuity to have committed the crimes in the same county. (Id., at p. 346.) The order granting the petition for a writ of habeas corpus is reversed. The original sentence imposing a full consecutive term of four years remains in effect. King, J., and Haning, J., concurred. A petition for a rehearing was denied December 23, 1983, and the opinion was modified to read as printed above. ShareThis “There are two novels that can change a bookish fourteen-year old’s life: The Lord of the Rings and Atlas Shrugged. One is a childish fantasy that often engenders a lifelong obsession with its unbelievable heroes, leading to an emotionally stunted, socially crippled adulthood, unable to deal with the real world. The other, of course, involves orcs.” ― Paul Krugman Support A Liberal's Hit List Twitter Feed About Hi, I'm Bret. I'm a very Progressive Liberal. I believe in the truth behind science and mathematics. I believe supposed "creationists" are just too ignorant to understand actual science, and fall back to their magic storybook because real science is too hard for their itsy-bitsy lizard brains. I believe in equality for all people; straight, gay, bi, trans, white, black, brown it does not matter. We are all humans on this Earth for a limited time. Celebrate diversity and enjoy with other's bring to your life. End of story. ;-) Neil Cavuto, for instance, hosted Gilchrist on his Fox News show Oct. 16, and mostly blew sunshine up Gilchrist's butt, talking about how he was a war hero, and didn't those mean students know he had fought for their free-speech rights, blah blah blah. Then he added: Cavuto: What the kids were saying in those pre-law classes was that you were going around, rounding up at the border illegal immigrants, was tantamount to, uh, physical abuse, some of them were saying. And that you were advocating violence. Now, I know that's not your schtick, or what you're saying, and it's

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likely coming up the main road—though he was prepared if they came over either ridge, too. The half-deads would try to swarm over the cops in the Hollow, and then Justinia Malvern would make her dramatic entrance, draining any survivors of blood before she went for the main prize. The paddy wagon. It stood in the middle of the clearing just waiting to be torn open so Malvern could get at the vampire hunter within. Of course Fetlock didn't plan to actually let that happen. His intention was to have his windbreakers engage the half-deads with a withering cross fire, then let Malvern come swooping in right into the sights of half a dozen snipers. Even then he had backup plans. The best sharpshooters he had might not be enough to take down a vampire, and he knew it—vampires were devilishly fast, and snipers were most effective against stationary targets. He claimed to have some surprises hidden in his mobile command center, things he wouldn't tell Clara and Glauer about. He also had his helicopter, though what it could do remained to be seen. "We had helicopters at Gettysburg," Glauer had told him, arguing patiently while Fetlock just gloated. "Didn't help much." "You used them there as support vehicles, mostly for intelligence gathering. Trust that I paid attention when I read your reports, Special Deputy." Glauer had shrugged and asked no more questions. So that was the trap, which Clara had to admit sounded formidable. Meanwhile Darnell was up on the ridges making sure it didn't prove too impregnable, that it didn't scare Malvern off before she even got into Fetlock's crosshairs. Fetlock and Urie Polder had figured out a way to make it look like the cops had foolishly ruined their own first line of defense. Rather than just take down the cordon of teleplasm and the perimeter of shrieking bird skulls, Darnell would tear down a few of the teleplasmic sheets as if he had been forced to do so to sneak in when he first started spying on the Hollow (he had actually been able to bypass them easily), then kick dirt over a couple of the skulls as if he'd carelessly disturbed them. They were fragile charms and easily disabled, and it was possible to make it look like he'd done so by accident. As a result of these efforts there would be a clear path for the half-deads to take through the defenses and right into Fetlock's traps, but it wouldn't look like they'd been given an engraved invitation. By the time the sun set behind the western ridge, everything was in place. As twilight fell across the tree-lined slopes that hemmed them in on either side, Clara felt the muscles of her back stiffen and tense. She watched the last rays of red sunlight cut through the puffy clouds as if she would never see them again. "Won't happen right away," Glauer told her. "I know," she replied. It was very unlikely that Malvern would strike exactly at sunset. She had to sleep all day in her coffin. They had no idea where that coffin might be, but it probably wouldn't be within ten miles of the Hollow. So she would have to travel to the trap, which might take ten minutes or it might take hours. And she was far too clever to stick to any expected timetable. She would strike when they least expected it. Which meant they had to expect it to come at any moment. Glauer and Clara kept wandering back and forth across the clearing, even as it grew so dark they could barely make out each other's faces in the twilight. Even when they started tripping on tree roots and rocks. They had not been given orders to stop. Every inch of Clara's skin prickled with fear. Every pore of her body exuded greasy fear sweat, though the temperature dropped rapidly as the darkness grew complete. Every instinct she had told her to run away. "Might not happen tonight," Glauer said, his voice strangely loud in the dimness. "You know it will," she said. Still. Fifteen minutes passed in full darkness, and nothing happened. An hour passed, and nothing happened. Two hours. "Oh my God, come on already!" Clara screamed, trying to break the tension. Nearby one of the windbreaker cops grabbed his gun and trained it on her, his eyes wide, his back heaving as he sucked in breath. Apparently she wasn't the only one going crazy with the waiting. She tried to control herself. She nearly jumped out of her skin when a radio crackled somewhere behind her. She spun around and saw Fetlock leaning out of the back of the mobile command center. Yellow light painted half his face. He had a walkie-talkie in one hand and he brought it up close to his mouth. "Unit Nine? Say again," he ordered. "Unit Nine reporting contact," the walkie-talkie replied. The man on the other end of the connection sounded tense and harried. "We have multiple subjects, moving through the tree line, at locations Whiskey Three and again at Yankee One. Repeat, we have—" The man fell silent. Clara couldn't move a muscle. All she could do was stand there and watch Fetlock's face. Nothing in it changed. "Unit Nine, say again," Fetlock ordered. But Unit Nine didn't repeat his information. Instead he started screaming, a terrible, tinny little sound coming from the walkie-talkie. The sound of a man being torn to pieces while he was still alive. There was no question. The attack was starting. ## 42. The Fed reached down and lowered the volume on his radio, but Clara knew the man up on the ridge was still screaming. She could hear it directly now, floating on the air. "Everyone stay frosty. Maintain your posts," Fetlock called to the cops in the Hollow. "This is what we planned for. What we've been training for the last month." There were a few cries of assent, of determination. Most of the cops just kept their heads down. They'd heard the stories. They knew what happened when the police tried to fight vampires. So did Clara. "Glauer," she said. "Glauer, this is going to get bad." "I know," he told her. "Now shut up." She started to protest, but she knew he was right. Worrying about what came next wouldn't change it. Talking about it only made the apprehension worse. "All sniper units, report in," Fetlock said into his walkie-talkie. One by one, eight men called in to report no contact. Up on the ridge the screaming stopped. Not as if the man up there had been finished off. Just as if he'd run out of breath and couldn't make any more noise. "He should bring up the helicopter—get a better visual on the situation—light some flares," Clara muttered. She couldn't help herself. "He should give us guns." "I know," Glauer said again. "Ground units, report in," Fetlock said. One by one the SWAT troopers and the windbreakers started calling in. Just confirming they were still alive. "Infrared, give me a report," Fetlock said. "No contact. No movement," the walkie-talkie said. "IR? Why is he using IR? Half-deads don't radiate heat. He should be using night vision instead, so—" "I _know_ ," Glauer insisted. Then he grabbed her arm. He must have seen something. Something Clara missed. Off to one side of them, a windbreaker cop started turning around, bringing his gun up. Something snatched him out of the dark and pulled him back into the woods, so fast he didn't have a chance to report on it. A moment later he started screaming. He was not fifteen yards away from where Clara and Glauer stood. The SWAT troopers opened fire on where he'd been. There was no way they could be sure they weren't shooting their own man, but they must have had orders to shoot anyway. Carbines barked and spat as bullets tore through the dark trees on that side of the Hollow. "Now, lights!" Fetlock called, and a bank of floodlights on top of the mobile command center swiveled in that direction and flared to life. Clara just had time to see a skinless face peering out from between two tree trunks before it flickered away, too fast to follow. More bullets snapped off in the direction of the half-dead, but it was long gone. "Ground units, fire at will," Fetlock called. But there was nothing to shoot. The man in the woods had stopped screaming almost at once. Clara listened hard for any kind of movement in those trees, peered into the shadows for any human-shaped silhouette. But there was nothing. "Guerrilla tactics," Glauer said. "What?" Clara demanded. "She knows that Fetlock wants a frontal assault. A big pitched battle. She won't give him that. She'll pick us off one by one. This isn't

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the Credit Information Bureau and offer legal, debt collection, personal bankruptcy and financial liquidity advice. Marshal Lion Finance offers guidance with bankruptcy proceedings, both company and personal, while at the same time financing the concurrent growth and projects using financial instruments selected specifically for the particular client. — experts at this division offer financial sector-related advice aiming to produce the best possible outcome for any client. This can include a range of financial services and loans. Additionally, Marshal Lion Finance will help the client improve their credit score with the Credit Information Bureau and offer legal, debt collection, personal bankruptcy and financial liquidity advice. Marshal Lion Finance offers guidance with bankruptcy proceedings, both company and personal, while at the same time financing the concurrent growth and projects using financial instruments selected specifically for the particular client. Marshal Lion Group — many years’ experience in the area of business strategy and planning allows the Marshal Lion Group to analyze a company’s situation thoroughly and propose customized solutions for the betterment of said situation. Our team of experts helps implement changes to the operations of a company aimed at optimizing them. Additionally, Marshal Lion Group helps clients set up corporate groups and then remains with the client if additional consultations are necessary. Good and effective help with planning involves setting specific objectives for a given project and then monitoring the process. This includes financial analysis, risk assessment, and improving the prospects of bountiful returns through financial and management optimization. Marshal Lion Group offers ready-to-go strategies developed based on analysis of a given company, its potential and potential drawbacks. Dedicated Online Platform Marshal Lion experts and its dedicated digital platform will make it much easier for investors (so far unable to do so) to invest in the non-bank loans market and profit from it. Everybody benefits from our modern and decentralized approach to finances which allows for the reduction in the number of middlemen, lower cost and less misunderstanding. Automation makes every process faster, cheaper and much, much safer. As part of our dedicated platform, Marshal Lion will make it possible to use its token to invest in the company’s products. Owing to smart contracts and decentralization allowing for unilateral analysis of any project by any potential investor, the safety of the process is guaranteed. The established market position enjoyed by Marshal Lion was won through over 3.000 loans granted to our clients and is testament to our experience, expertise and very deep understanding of the subject matter together with the associated legal and financial intricacies. Our token is, therefore, a boon for an investor and an outstanding diversifying asset for any wallet. WEB: https://marshalliongroup.com Facebook: https://www.facebook.com/Marshal-Lion-Group-1764544916981990/ Instagram: https://www.instagram.com/marshalliongroup_com/ LinkedIn: https://www.linkedin.com/in/marshal-lion-group-18a0a018a/ Twitter: https://twitter.com/marshal_lion Medium: https://medium.com/@marshal_lion Reddit: https://www.reddit.com/user/MarshalLionGroup Telegram: https://t.me/marshal_lionNFL Draft Report Tannehill headlines five visitors to One Bills Drive With the deadline to bring prospects for the 2012 NFL Draft looming on Wednesday, the Buffalo Bills brought in what will likely be their final pre-draft visitors to team facilities on Tuesday. According to BuffaloBills.com, Texas A&M quarterback Ryan Tannehill, South Carolina defensive end Melvin Ingram, Mississippi State defensive tackle Fletcher Cox, South Carolina cornerback Stephon Gilmore and Oklahoma cornerback Jamell Fleming all made the visit to One Bills Drive. If this were two months ago, Ingram visiting would probably be the headline. But with both Mario Williams and Mark Anderson signed to the Bills via free agency, combined with how Buddy Nix views the defensive end class at the top of the draft, it doesn't appear as though he'll be the player selected at 10. Gilmore is an intriguing case. Numerous reports have him shooting up draft boards. Peter King of Sports Illustrated thinks he could go as high as seventh to Jacksonville. With the Bills in need of a cornerback, he could be on the short list of candidates the Bills could think about for their selection at tenth overall. Fleming is a second-tier type of cornerback that could be had on the second day of the draft at some point. As for Tannehill, you can read about how to look in to his visit to Buffalo here. All in all that's 26 total visits that were reported. Teams are allowed a grand total of 30, so it's very possible four players snuck in and out of Buffalo without it being reported.Q: How to disable Client-side Validation for an XPage? I know i can disable for the server or application in the xsp.properties via: xsp.client.validation=false And at the control level via: disableClientSideValidation="true" Short of setting disableClientSideValidation for each control, is there any way to disable at the XPage level? A: Please try the following: <?xml version="1.0" encoding="UTF-8"?> <xp:view xmlns:xp="http://www.ibm.com/xsp/core"> <xp:this.properties> <xp:parameter name="xsp.client.validation" value="false" /> </xp:this.properties> </xp:view> Q: startActivityForResult(Intent, int) what is the purpose of the integer argument I am following a tutorial that uses "startActivityForResult" function. I know why this function is used and if we want to use the returned data, we use onActivityResult() function. The thing that I wana know is, why do we pass an Integer to startActivityForResult() function? And where is it used? Thanks for your kind help! A: When the Activity that you're starting finished, that second argument is passed to the method onActivityResult() of the calling Activity. This is to distinguish different results from one another. You may have a case where an Activity needs to call several others for results, and by specifying a unique int for each of them, you can determine the correct thing to do when you get a result. Edit: Here's an example. Suppose you have a screen (Activity A) where you choose a picture from your gallery, and you choose a friend to send it to. You'll start an activity to pick a picture from the gallery on a button click, and maybe you also have a "friend picker" activity which you can also start from Activity A. You want both of those activities to return the data the user selected. onActivityResult() will get called on Activity A when the user finishes with the two activities described above. By specifying the requestCode for startActivityForResult() for the gallery activity, and your "friend picker", you know what to do in onActivityResult(). Also, note that you don't need a complicated scheme for requestCode. You could just pass in the values 1 and 2 for the gallery and friend picker, respectively. {.NET + SQL_Server + Azure + devLeadership + technology} Menu Rocky Lhota at CNUG I had a chance to ask Rocky a couple of questions that had been bugging me about CSLA. 1) He agreed that using the method of multiple result sets in datareader is not really a good idea in some instances, where a dataset would be much more useful. 2) He suggested that you should usually not have an object that is sometimes a child and sometimes a parent. I am not sure I agree with idea. I believe I understand his point that if you are dealing with a Project object that has a collection of Employees assigned to it, you probably don’t need the Employees to be as complex as if you were dealing with an Employee who is assigned to a bunch of Projects, but at the same time you are talking about writing 2 classes with 2 sets of data access scripts, vs 4 classes and 4 sets of data access. But, he said that there are techniques for making a business object be both a parent and a child. This is apparently detailed in Ch 7. 3) He mentioned that people have built UI Frameworks that run on top of CSLA. I will have to look into this. 4) He was showing an example using an ASP.NET MultiView control, looked like a great way to enable multiple views of the same data. 5) I didn’t get a chance to ask him about serialization and deserialization of classes that have small differences. For example if you serialze an object and use the same byte array to deserialize a similar class, will it blow up if small changes are made, like you add a public property? I will have to try this out myself. In all, Rocky was a very good speaker. Very engaging, funny, and on point. Oh and I won the raffle at the end, to get a copy of his book, the one I just paid 60 bucks for :-).package handlers import ( "fmt" "net/http" "net/url" "github.com/docker/distribution" dcontext "github.com/docker/distribution/context" "github.com/docker/distribution/reference" "github.com/docker/

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for its breadth," FMC Corp. v. Holliday, 498 U.S. 52, 58, 111 S.Ct. 403, 112 L.Ed.2d 356 (1990), and "deliberately expansive, and designed to establish pension plan regulation as exclusively a federal concern," Pilot Life Ins. Co. v. Dedeaux, 481 U.S. 41, 46, 107 S.Ct. 1549, 95 L.Ed.2d 39 (1987) (internal quotation omitted). More recently, however, the Supreme Court has narrowed the preemptive scope of ERISA, moving away from the broadest meaning of the provision. The Court has stated that the phrase "insofar as they ... relate" contains words of limitation that were purposefully written into the statute. N.Y. State Conference of Blue Cross & Blue Shield Plans v. Travelers Ins. Co., 514 U.S. 645, 655, 115 S.Ct. 1671, 131 L.Ed.2d 695 (1995). If the term "relate to" was allowed to reach to its most logical extension, "pre-emption would never run its course." Id.; see also Cal. Div. of Labor Standards Enforcement v. Dillingham Constr., N.A., 519 U.S. 316, 335, 117 S.Ct. 832, 136 L.Ed.2d 791 (1997) (Scalia, J. concurring) (noting that "applying the `relate to' provision according to its terms was a project doomed to failure, since, as many a curbstone philosopher has observed, everything is related to everything else"). The effect of such a broad reading "would be to read Congress's words of limitation as mere sham, and to read the presumption against pre-emption out of the law whenever Congress speaks to the matter with generality." Travelers Ins. Co., 514 U.S. at 655, 115 S.Ct. 1671. 12 Therefore, in interpreting ERISA's preemption clause, a court "must go beyond the unhelpful text and the frustrating difficulty of defining its key term, and look instead to the objectives of the ERISA statute as a guide to the scope of the state law that Congress understood would survive." Id. at 656, 115 S.Ct. 1671. The purpose of ERISA preemption was to avoid conflicting federal and state regulation and to create a nationally uniform administration of employee benefit plans. Thus, ERISA preempts state laws that (1) "mandate employee benefit structures or their administration;" (2) provide "alternate enforcement mechanisms;" or (3) "bind employers or plan administrators to particular choices or preclude uniform administrative practice, thereby functioning as a regulation of an ERISA plan itself." Coyne & Delany Co. v. Selman, 98 F.3d 1457, 1468 (4th Cir.1996) (outlining the three categories of state laws recognized in Travelers that are preempted by ERISA) (internal citations omitted). Congress did not intend, however, for ERISA "to preempt traditional state-based laws of general applicability that do not implicate the relations among the traditional ERISA plan entities, including the principals, the employer, the plan, the plan fiduciaries, and the beneficiaries." LeBlanc v. Cahill, 153 F.3d 134, 147 (4th Cir.1998). 13 Since the Travelers decision, the Supreme Court has reiterated the approach of looking to the objectives of ERISA to guide its preemption decisions. See, e.g., Dillingham Const., 519 U.S. at 325, 117 S.Ct. 832 (finding that California's prevailing wage law, which has only an indirect economic effect on employee benefit plans, is not preempted by ERISA); De Buono, 520 U.S. at 815-16, 117 S.Ct. 1747 (upholding state tax on health care facilities operated by an ERISA fund). We too have followed the Travelers approach in applying ERISA preemption in our recent cases. In Smith v. Provident Bank, 170 F.3d 609, 615-16 (6th Cir.1999), we held that an ERISA plan's state-law claims against a trustee were preempted because Congress established the exclusive means by which fiduciary duties would be enforced. We noted, however, that where "an ERISA plan's relationship with another entity is not governed by ERISA, it is subject to state law." Id. at 617. Similarly, in Marks v. Newcourt Credit Group, Inc., 342 F.3d 444, 453 (6th Cir.2003), we found that a breach-of-contract claim was not preempted where the conduct at issue related to the "employment contract irrespective of the plan" even though resolution of the claim affected the plaintiff's right to plan benefits. Though we have yet to address the issue specifically, other courts of appeals have followed a similar approach and held that ERISA does not preempt state-law claims brought against non-fiduciary service providers in connection with professional services rendered to an ERISA plan. See, e.g., Gerosa v. Savasta & Co., 329 F.3d 317, 330 (2d Cir.2003) (concluding that ERISA does not preempt plan's state-law claim against an actuary which resulted in severe under-funding of ERISA plan), cert. denied, 540 U.S. 967, 124 S.Ct. 435, 157 L.Ed.2d 312 (2003) and cert. denied, 540 U.S. 1074, 124 S.Ct. 929, 157 L.Ed.2d 744 (2003); Ariz. State Carpenters Pension Trust Fund v. Citibank, 125 F.3d 715, 724 (9th Cir.1997) (concluding that a plan could bring a state-law claim for breach of custodial agreement against a bank as non-fiduciary service provider); Coyne & Delany Co., 98 F.3d at 1466, 1472 (holding that state malpractice claims against insurer for negligently failing to obtain replacement insurance plan was not preempted); Airparts Co. v. Custom Benefit Servs., 28 F.3d 1062, 1066 (10th Cir.1994) (concluding that trustee's common-law suit against outside financial consultant is not preempted). 14 Applying these principles to this case, we conclude that the magistrate judge erred in his analysis of PONI's state-law claims against NCB and MVP. The magistrate judge found that because PONI's breach-of-contract claims arise out of obligations relating to the servicing of ERISA plans, the claims against both NCB and MVP are preempted. The mere fact that an employee benefit plan is implicated in the dispute, however, is not dispositive of whether the breach-of-contract claims are preempted. PONI argues that its state-law claims relate solely to the Appellees' record-keeping services and should be viewed separately from the plans themselves. With regard to the claim against NCB, we find that argument to be unpersuasive. 15 NCB serves as trustee to the Savings Plan and also provides record-keeping and commercial-banking services. NCB's record-keeping obligations arise out of the Savings Plan itself, which contains provisions outlining the top-heavy rules and requiring coordination of top-heavy testing among multiple plans.1 In the prior cases in which the courts have found that ERISA does not preempt state-law claims against non-fiduciary service providers, a service agreement or contract separate and distinct from the ERISA qualified plan served as the basis for the claim. See Marks, 342 F.3d at 453 (allowing suit for breach of employment contract); Gerosa, 329 F.3d at 319 (permitting suit on actuarial contract); Ariz. State Carpenters, 125 F.3d at 718 (allowing claim for breach of custodial agreement); Coyne & Delany, 98 F.3d at 1471 (permitting malpractice claim on contract to design benefit plan); Airparts Co., 28 F.3d at 1066 (permitting suit on a consulting contract). In this case, by contrast, all of NCB's obligations arise from the plan itself, and thus the breach-of-contract claim is necessarily a claim that a fiduciary breached the terms of the ERISA plan. 16 PONI argues that even if the contract upon which it is suing NCB is the ERISA plan, preemption does not apply to a state-law breach-of-contract claim for NCB's failure to perform its non-fiduciary duties under the plan. PONI correctly contends that an entity may serve both in a fiduciary and non-fiduciary capacity, because fiduciary status under ERISA turns on function rather than form. Pegram v. Herdrich, 530 U.S. 211, 225-26, 120 S.Ct. 2143, 147 L.Ed.2d 164 (2000). Indeed, where the alleged conduct by the fiduciary is "entirely unrelated to and outside the scope of [the fiduciary's] duties under the plan or in carrying out the terms of the plan," courts have found that ERISA's core objectives are not implicated and state-law claims may proceed. Darcangelo v. Verizon Communications, Inc., 292 F.3d 181, 193 (4th Cir.2002); see also Dishman v. UNUM Life Ins. Co., 269 F.3d 974, 984 (9th Cir.2001) (holding that ERISA does not provide fiduciaries "with blanket immunity from garden variety torts which only peripherally impact daily plan administration"). In this case, however, because the contract at issue in the

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from this insight. **Contributors:** RdR wrote this paper, under supervision of SJSS, CJHvdK, SAEP, and CDAS. All authors reviewed the draft paper and provided critical intellectual content. All authors approved the final version of the manuscript and its submission to BMJ Open Diabetes Research & Care. CDAS is taking responsibility for the contents of the article. **Funding:** This study was supported by ZonMw (project no 849200001), the European Regional Development Fund via OP-Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant 31O.041), Stichting De Weijerhorst (Maastricht, the Netherlands), the Pearl String Initiative Diabetes (Amsterdam, the Netherlands), CARIM, School for Cardiovascular Diseases (Maastricht, the Netherlands), School CAPHRI, Care and Public Health Research Institute (Maastricht, the Netherlands), NUTRIM, School of Nutrition and Translational Research in Metabolism (Maastricht, the Netherlands), Stichting Annadal (Maastricht, the Netherlands), Health Foundation Limburg (Maastricht, the Netherlands) and by unrestricted grants from Janssen-Cilag B.V. (Tilburg, the Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, the Netherlands) and Sanofi-Aventis Netherlands B.V. (Gouda, the Netherlands). **Competing interests:** None declared. **Patient consent for publication:** Not required. **Ethics approval:** The study has been approved by the institutional medical ethical committee (NL31329.068.10) and the Minister of Health, Welfare and Sports of the Netherlands (Permit 1 31 088--1 05 234 PG). **Provenance and peer review:** Not commissioned; externally peer reviewed. **Data availability statement:** Data are available upon reasonable request. Rose Setten Rose Setten (born 22 August 1988, in Shoreham-by-Sea, England) was the 2004 winner of BBC Young Choirgirl of the Year. Setten's achievement was particularly noteworthy because at the time she was head chorister at a small provincial parish with limited resources, All Saints Church in Findon Valley, and was competing against professional choristers from York Minster and Winchester Cathedral, amongst others. She completed her schooling at Davison High School and Brighton Hove & Sussex Sixth Form College. She started singing lessons at the age of 11, and has performed on Songs of Praise and BBC Radio 4's Sunday Half Hour. Setten studied at the Royal Northern College of Music and obtained a first class honours degree in June 2010. She then attended the Royal Academy of Music under Elizabeth Richie as a Mezzo Soprano until June 2013 having been awarded a Distinction in her M.A. as well as the prestigious Dip RAM. In September 2013, Setten commenced studies on the Artist Diploma course at The Benjamin Britten International Opera School at the Royal College of Music. Here, she took the lead role of L'Enfant in L'Enfant et les Sortileges in December 2013. She followed this by playing the part of Tauride in the RCM's March 2014 production of Arianna in Creta, which was part of the London Handel Festival. In November 2014 Setten took the part of Zweite Dame in Die Zauberflote at the RCM . She will be appearing in Cosi Fan Tutte at Garsington Opera in July 2015 covering the role of Dorabella . External links Category:People from Shoreham-by-Sea Category:Living people Category:1988 births Category:21st-century English singers Category:21st-century English women singersQ: "stroke-dasharray:x,y;" mess up svg path? (Chrome) Edit > Fixed: https://bugs.chromium.org/p/chromium/issues/detail?id=364866 Works I generate svg paths via d3js. Either data() + mesh() or datum() + mesh() work. svg.append("g").attr("id","border") .attr("style", "fill: none; stroke:#646464;") .selectAll("path") .data([topojson.mesh(json, L0, function(a, b) { return a !== b; })]) .enter().append("path") .attr("d", path); or : //inland borders lines svg.append("g").attr("id","coast") .attr("style", "fill: none; stroke:#646464;") .append("path") .datum(topojson.mesh(json, json.objects.admin_0, function(a,b){return a===b;})) .attr("d", path); Breaks Adding stroke-dasharray: 8,4 result into: Changing it to stroke-dasharray: 6,3,3,3 result into: Some artifacts appears, and half of the strokes are missing/invisible (borders with Ind/Pakistan, Ind/Nepal, Ind/Myamar, Myamar/Cambodia). If I add a similar stroke-dasharray to the coastline generation, same mess appear with blue lines. Edit: Ok. First, i'am squizzed because the topojson.mesh() always return a single MultiLineString which, in turn, generate a single path. But why is it that the "dasharray:none" works fine !?? Any idea ? I think these dasharray makes a portions of the path not closed. (check up ongoing). Link to live code: https://rugger-demast.codio.io/2_zoom/index.html A: This is a known bug in Chrome: https://code.google.com/p/chromium/issues/detail?id=364866 Edit > Fixed: https://bugs.chromium.org/p/chromium/issues/detail?id=364866 Nigerians: Are You Better Off Today Than You Were Four Years Ago? By Bayo Oluwasanmi During the American presidential debate in 1980 with the incumbent President Jimmy Carter, candidate Ronald Reagan pointedly asked Americans: “Are you better off today than you were four years ago? Ever since, the now-famous quote features prominently every four years in the American political discourse. That one-liner has become a line that people all over the world can personally relate to in many ways.In 2015, former President Goidluck Ebele Jonathan humiliated at the polls was a goner. The departure of the native son of Otueke aroused near-erotic ecstasy of Nigerians who loathed him with such intensity it’s hard to think of a comparison with any democratically elected president in Nigeria. Candidate Muhammadu Buhari is not in any way near an orator. He’s not a fast thinker. He’s slow in decision making and sluggish in action. He prevaricates. But on the promise of killing corruption before corruption kills us, Buhari was overwhelmingly elected president.Riding on populist agenda to fight corruption and sanitize our nation of all economic and social demons of all sorts, he took office May 29, 2015 with Nigerians weeping with happiness. It was a time of a lot of eager, nostalgic, and liberal feelings among Nigerians. The acceptance of and respect for Buhari were tellingly electrifying. Now nearing its four-year term, the Buhari administration was the beginning of the end of a society that bears resemblance to a country with a government. His presidency has become a misery memoir. I hope Nigerians have learned their lesson.History is an amazing guide if Nigerians chose to pay attention to it. But sadly, many Nigerians don’t give a damn. Nigerians, consider the following and conclude whether you were better off today than you were four years ago when Buhari took office.Real change was Buhari’s slogan. His populist agenda of fighting corruption, creating jobs, guarantee of safety and security, extermination of Boko Haram terrorists, and the hope for the realization of common dreams of all Nigerians evaporated like tantalizing mirage.We don’t need a fictional George Orwell to tell us that basic infrastructures are non-existent in Nigeria. Like ancient curse, the same old problems continue to haunt Nigerians. The solutions proferred and preferred by Buhari administration to the old problems are laughable. For water, dig borehole. For electricity, buy generators. For roads, get comfortable on pothole roads. For public transportation, hop on okada (commercial bike). For police rely on neighborhood vigilantes. For public housing, sleep under Eko Bridge. For jobs, sell re-loadable calling cards. Better still, give market women who sell peppers, iru, ogiri, yam, etc., N10,000 and call it TraderMoni. And for health, don’t get sick and if you’re sick, die quickly. Under Buhari administration, political and socioeconomic reforms continue to suffer. His regime is characterized by economic stagnation, run away corruption. The whole country is a dysfunctional mess. His government is very good at manufacturing problems where non existed. It was a regime of reign of political and economic terror.

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localNotification.soundName = UILocalNotificationDefaultSoundName; localNotification.applicationIconBadgeNumber = 1; [[UIApplication sharedApplication] scheduleLocalNotification:localNotification]; } A: First of all you should consider the fact that UILocalNotification class that you are using is deprecated starting from iOS 10. Since iOS 10 there is no distinction between local and remote notifications. In UserNotifications framework (iOS 10.0+, Swift | Objective-C) one does not create instances of UNNotification like in some of the previous implementations of similar frameworks / API's by Apple. Instead, an instance of UNNotificationCenter is responsible for creating notification objects and calls delegate methods when new notifications are received and before the default UI will be displayed. See Apple's documentation for more details on the requirements for conforming UNUserNotificationCenterDelegate protocol. I often end up using AppDelegate as a class conforming to that protocol Now back to the question. To initiate a creation of the notification from within the app first you should create a trigger (in your case you might want to use UNTimeIntervalNotificationTrigger), then create a notification request and finally add the request to the notification center singleton that can be accessed by calling UNUserNotificationCenter.current(). let content = UNMutableNotificationContent() content.title = "Alert Fired" Create a trigger that will determine the moment when UNUserNotificationCenter will invoke the notification let trigger = UNTimeIntervalNotificationTrigger(timeInterval: 0, repeats: false) Create a notification request. You only create those to invoke local notifications, since iOS is responsible for creating request objects for incoming push notifications. let request = UNNotificationRequest(identifier: "FiveSecond", content: content, trigger: trigger) Now we will have to add our request to the current notification center associated with our app. let center = UNUserNotificationCenter.current() center.add(request, withCompletionHandler: nil) In our case the notification will be triggered immediately by the UNUserNotificationCenter. Q: Who exactly knew that Chancellor Palpatine was Darth Sidious? There are only few people who know it. I can include the following people: Count Dooku/Darth Tyranus - I'm sure he told Dooku, because he played such a huge role in Palpatine's plans and the war, so he would always have to know what's going on. Plus by the look on his face when Palpatine told Anakin to kill him, he looked at him like he knew who he was. Mas Amedda - I think he knew, because Palpatine would have told him so they could work together in the Galactic Senate to get whatever results Palpatine wanted, plus in an episode of The Clone Wars, Palpatine says something to him about his plan coming together. Sly Moore - I think she had as much of a major role with Palpatine and the Galactic Senate as Mas Amedda did. During the speech of the Emperor in Revenge of the Sith, she was there. Did Darth Maul and General Grievous know that Palpatine is Darth Sidious? Note: the idea for this question came from http://boards.theforce.net/threads/who-exactly-knew-chancellor-palpatine-was-darth-sidious.50009052/ A: Besides those you mentioned, a few others knew his identity. Ahsoka Tano: The shadow was almost certainly one of the dark side’s creatures. Ahsoka had no idea what sort of thing it might be, but whatever it was couldn’t be that powerful, because it hadn’t been able to track down Hedala. That ruled out Palpatine himself, not that the Emperor could just show up on a planet without causing a great deal of alarm. (Ahsoka) Eneb Ray: While it's never explicitly stated in the canon that Maul knew, it's very likely he made the connection at some point, given that he recognized the Empire as his enemy. He did know in the Legends continuity, though. What then if- beyond contemplation- something should befall his Master? Unlike Darth Sidious, who masqueraded as Republic Senator Palpatine and debated complex issues in the Senate, Maul lacked a secret identity. With his yellow eyes and horned head a black-and-red mask of arcane sigils, it was all he could do to prowl the fringes of The Works in the dead of night without instilling fear in nearly every being whose gaze he caught. (Darth Plagueis) Yoda, Windu and the various other Jedi who learned his identity in Revenge of the Sith, as well as Luke Skywalker. Tarkin had his suspicions: Tarkin may also have determined that Vader was a Sith. If so, it followed that he accepted that Sidious was Vader’s dark side Master. (Tarkin) Grievous did not know. 3.19 lakh rats killed in 7 days? BJP leader Eknath Khadse wants a probe. (File Photo) 3.19 lakh rats killed in 7 days? BJP leader Eknath Khadse wants a probe. (File Photo) In a startling revelation, BJP leader Eknath Khadse alleged Thursday that the company awarded a contract for pest control in the state secretariat has claimed that it killed 3,19,400 rats in seven days. The work order to a private company was given by the General Administration Department of the Maharashtra government, under Chief Minister Devendra Fadnavis. A former minister, Khadse told the Vidhan Sabha there was something rotten which needed a thorough investigation to get to the rats playing hide and seek in government’s headquarters at Mantralaya, the state secretariat. “A company which was given the award for killing rats has claimed it killed 3,19,400 rats within seven days in Mantralaya,” he said. Raising more questions, he said, “Can there be so many rats in Mantralaya? And would it be ever possible to execute such an exercise within seven days.” Dismissing such statistics and claims as bizarre, he said, “The government should conduct a probe in the entire matter.” “The government will probe the matter to ascertain the facts about the company, tender process and job.” “The government will probe the matter to ascertain the facts about the company, tender process and job.” The Brihanmumbai Municipal Corporation has managed to kill six lakh rats in two years in the entire city of Mumbai, he said, which begs the question of where has the private company spotted so many rodents. The GAD issued the work order to the company based on a survey which allegedly said there were 3,19,400 rats in Mantralaya and the company was given six months to get rid of them all. If these statistics are true, it means “They had to kill 45,628.57 rats a day. Now, those 0.57 must be the new born ones,” Khadse said. He also said that it must be a super-efficient company to have been able to kill 31.68 rats every half minute, evoking laughter in the state Assembly. “The total weight of these rats which were killed would be 9,125.71 kg. It would mean one truck would be required to carry the dead rodents and get them disposed.” Strangely, he said, nobody in the Mantralaya had seen this exercise conducted. Unwilling to let the issue go, Khadse wondered why the government did not deploy ten cats to do the job. Now, if they had set the cats loose it would have worked effectively and free of cost, he said. In his reply to a debate on budgetary demands, Maharastra minister of state for GAD, Madan Yerawar said, “The government will probe the matter to ascertain the facts about the company, tender process and job.” BJP MLA Charansingh Waghmare, who sought information on the alleged irregularities under RTI said, “The contract was given to a Labour Society. It was for six months. It was reduced to two months. But the company claimed the work was over within seven days. The bill book shows the work was done within the period between May 3 and May 10, 2016.” He also said, “ There was no tendering process was followed. I have already complained this matter to Chief Minister’s Office. I have sought a probe.” 📣 The Indian Express is now on Telegram. Click here to join our channel (@indianexpress) and stay updated with the latest headlines For all the latest India News, download Indian Express App.In addition to all of the problems Whitaker describes in the linked article—failed diagnostics, failed theories, failed “disease models,” failed treatments, making matters worse for the mentally ill, and drugging children and minors without their consent—I would further submit that our generally accepted model of the human mind itself is as deeply flawed. Rather than starting with the idea that humans have or develop personalities that do or don’t adapt well to some ambiguous social standard, we would do better to start with the idea that humans are fundamentally interactive beings, beings that communicate. If our interactions are good, we will be well enough. If our communications

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part of the history of the Roman empire. While that great body was invaded by open violence, or undermined by slow decay, a pure and humble religion gently insinuated itself into the minds of men, grew up in silence and obscurity, derived new vigor from opposition, and finally erected the triumphant banner of the Cross on the ruins of the Capitol. Nor was the influence of Christianity confined to the period or to the limits of the Roman empire. After a revolution of thirteen or fourteen centuries, that religion is still professed by the nations of Europe, the most distinguished portion of human kind in arts and learning as well as in arms. By the industry and zeal of the Europeans, it has been widely diffused to the most distant shores of Asia and Africa; and by the means of their colonies has been firmly established from Canada to Chili, in a world unknown to the ancients. But this inquiry, however useful or entertaining, is attended with two peculiar difficulties. The scanty and suspicious materials of ecclesiastical history seldom enable us to dispel the dark cloud that hangs over the first age of the church. The great law of impartiality too often obliges us to reveal the imperfections of the uninspired teachers and believers of the gospel; and, to a careless observer, their faults may seem to cast a shade on the faith which they professed. But the scandal of the pious Christian, and the fallacious triumph of the Infidel, should cease as soon as they recollect not only by whom, but likewise to whom, the Divine Revelation was given. The theologian may indulge the pleasing task of describing Religion as she descended from Heaven, arrayed in her native purity. A more melancholy duty is imposed on the historian. He must discover the inevitable mixture of error and corruption, which she contracted in a long residence upon earth, among a weak and degenerate race of beings. [102] [Footnote 102: The art of Gibbon, or at least the unfair impression produced by these two memorable chapters, consists in confounding together, in one undistinguishable mass, the origin and apostolic propagation of the Christian religion with its later progress. The main question, the divine origin of the religion, is dexterously eluded or speciously conceded; his plan enables him to commence his account, in most parts, below the apostolic times; and it is only by the strength of the dark coloring with which he has brought out the failings and the follies of succeeding ages, that a shadow of doubt and suspicion is thrown back on the primitive period of Christianity. Divest this whole passage of the latent sarcasm betrayed by the subsequent one of the whole disquisition, and it might commence a Christian history, written in the most Christian spirit of candor.--M.] Our curiosity is naturally prompted to inquire by what means the Christian faith obtained so remarkable a victory over the established religions of the earth. To this inquiry, an obvious but satisfactory answer may be returned; that it was owing to the convincing evidence of the doctrine itself, and to the ruling providence of its great Author. But as truth and reason seldom find so favorable a reception in the world, and as the wisdom of Providence frequently condescends to use the passions of the human heart, and the general circumstances of mankind, as instruments to execute its purpose, we may still be permitted, though with becoming submission, to ask, not indeed what were the first, but what were the secondary causes of the rapid growth of the Christian church. It will, perhaps, appear, that it was most effectually favored and assisted by the five following causes: I. The inflexible, and if we may use the expression, the intolerant zeal of the Christians, derived, it is true, from the Jewish religion, but purified from the narrow and unsocial spirit, which, instead of inviting, had deterred the Gentiles from embracing the law of Moses. II. The doctrine of a future life, improved by every additional circumstance which could give weight and efficacy to that important truth. III. The miraculous powers ascribed to the primitive church. IV. The pure and austere morals of the Christians. V. The union and discipline of the Christian republic, which gradually formed an independent and increasing state in the heart of the Roman empire. [Footnote!: Though we are thus far agreed with respect to the inflexibility and intolerance of Christian zeal, yet as to the principle from which it was derived, we are, toto coelo, divided in opinion. You deduce it from the Jewish religion; I would refer it to a more adequate and a more obvious source, a full persuasion of the truth of Christianity. Watson. Letters Gibbon, i. 9.--M.] I. We have already described the religious harmony of the ancient world, and the facility [102] with which the most different and even hostile nations embraced, or at least respected, each other's superstitions. A single people refused to join in the common intercourse of mankind. The Jews, who, under the Assyrian and Persian monarchies, had languished for many ages the most despised portion of their slaves, [1] emerged from obscurity under the successors of Alexander; and as they multiplied to a surprising degree in the East, and afterwards in the West, they soon excited the curiosity and wonder of other nations. [2] The sullen obstinacy with which they maintained their peculiar rites and unsocial manners, seemed to mark them out as a distinct species of men, who boldly professed, or who faintly disguised, their implacable habits to the rest of human kind. [3] Neither the violence of Antiochus, nor the arts of Herod, nor the example of the circumjacent nations, could ever persuade the Jews to associate with the institutions of Moses the elegant mythology of the Greeks. [4] According to the maxims of universal toleration, the Romans protected a superstition which they despised. [5] The polite Augustus condescended to give orders, that sacrifices should be offered for his prosperity in the temple of Jerusalem; [6] whilst the meanest of the posterity of Abraham, who should have paid the same homage to the Jupiter of the Capitol, would have been an object of abhorrence to himself and to his brethren. But the moderation of the conquerors was insufficient to appease the jealous prejudices of their subjects, who were alarmed and scandalized at the ensigns of paganism, which necessarily introduced themselves into a Roman province. [7] The mad attempt of Caligula to place his own statue in the temple of Jerusalem was defeated by the unanimous resolution of a people who dreaded death much less than such an idolatrous profanation. [8] Their attachment to the law of Moses was equal to their detestation of foreign religions. The current of zeal and devotion, as it was contracted into a narrow channel, ran with the strength, and sometimes with the fury, of a torrent. [Footnote 102: This facility has not always prevented intolerance, which seems inherent in the religious spirit, when armed with authority. The separation of the ecclesiastical and civil power, appears to be the only means of at once maintaining religion and tolerance: but this is a very modern notion. The passions, which mingle themselves with opinions, made the Pagans very often intolerant and persecutors; witness the Persians, the Egyptians even the Greeks and Romans. 1st. The Persians.--Cambyses, conqueror of the Egyptians, condemned to death the magistrates of Memphis, because they had offered divine honors to their god. Apis: he caused the god to be brought before him, struck him with his dagger, commanded the priests to be scourged, and ordered a general massacre of all the Egyptians who should be found celebrating the festival of the statues of the gods to be burnt. Not content with this intolerance, he sent an army to reduce the Ammonians to slavery, and to set on fire the temple in which Jupiter delivered his oracles. See Herod. iii. 25--29, 37. Xerxes, during his invasion of Greece, acted on the same principles: l c destroyed all the temples of Greece and Ionia, except that of Ephesus. See Paus. l. vii. p. 533, and x. p. 887. Strabo, l. xiv. b. 941. 2d. The Egyptians.--They thought themselves defiled when they had drunk from the same cup or eaten at the same table with a man of a different belief from their own. "He who has voluntarily killed any sacred animal is punished with death; but if any one, even involuntarily, has killed a cat or an ibis, he cannot escape the extreme penalty: the people drag him away, treat him in the most cruel manner, sometimes without waiting for a judicial sentence. * * * Even at the time when King Ptolemy was not yet the acknowledged friend of the Roman people, while the multitude were paying court with all

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. The trelliswork around the door supports a spindly climber, Mummy holds little Ian – who's one and a half, maybe two? – like a misshapen rugby ball that someone has passed her; and which she wishes she could immediately pass-kick forward, beyond the touchline of maturity. But in place of Daddy, there's just this painted-in glob, this fuzzy outline. Somebody has got at my eidetic memory and retouched it. They've removed Daddy the way that the Stalinist propagandists painted out Trotsky. When Lenin arrived at the Finland Station and mounted the crude, hastily erected rostrum, Lev Davidovich was there. But as Vladimir ranted, Lev, like some Cheshire Cat, began to fade, the planks started to show through his brow; eventually all that was left was a stain. It's the same for the rest of my childhood. At all the Party Congresses that we know Daddy to have attended, he has been negated, erased, excised from the picture. Whether propped against the bonnet of the family Mark 1 Cortina (same birthdate as my own), or sprawled on the sheep-cropped and sheep-bedizened grass around the Chantry, it's the same. Only Mummy and Ian, or Mummy, Ian and maternal relatives – plus this Daddy-absence; this Daddy-vacuity; this Daddy-erasure. I am a big man, like my father. I have his mousy hair and low forehead. I couldn't possibly be said to be ugly, for my features, in themselves, are shapely enough. The cratered dimple in my chin lines up precisely with the scoop out of my top lip and the narrow bridge of my long nose. No, my problem is the same as Daddy's – my features are marooned, set too far in to the middle of my wide face. Furthermore, the way everything falls away at the edges of my face is rather unpleasant. It gives a sodden, lippy impression, like the margin of a peat bog. I have my father's figure as well. Sometimes, when I inadvertently catch sight of myself getting out of the bath, I freeze, startled, and think: Who let that Russian peasant woman in here? But it's only me, because – you see – my hips are wider than my shoulders and my solid legs look as if babies could be squeezed out from their confluence as easily as grapefruit pips. I'm built like a babushka. And another thing, another point of resemblance. When I was a child I was reasonably well co-ordinated, but as I have grown up my sense of body has become both cloudy and diffuse. My fingers and toes are now distant provinces, Datias and Hibernias, cut off for years at a time from the Imperial nervous system. Without The Fat Controller's instruction in the blacker arts of physicality I would undoubtedly have become as hamfisted as Dad was. I certainly look as if I ought to be. If I mention my father at the outset, it is because I want to get his having been out of the way, out of the way. After all nurture has trumped nature a thousandfold as far as my being is concerned. And if I were to see Dad now (I have no idea if he is alive or dead), I should feel compelled to dispose of him. I have no doubt about that. His presence would be an affront to my body; so, for it, there would be the rare delight of extinguishing an imperfect and distressed version of itself, a prototype, a maquette. I should enjoy the bludgeoning of my own features, the pulverising of my own thick bones and the slashing to ribbons of the nauseating congruence of our flesh – more, perhaps, than I've enjoyed any of my other little outrages. Why, oh why, oh whyeeee! Why did Daddy abandon me like that? That's the $64,000 question, that's the Golden Shot. Why didn't he care for me, love me? He must – I am forced to conclude – have been a weakling, an emotional eunuch. That much is certain. He stepped aside and indifferently flicked a wet blanket at the raging bull of paternity. For that I can never forgive him. When I was at university, The Fat Controller saw fit to supplement that version of my father's history that my mother had retailed when I was a child. It is characteristic of The Fat Controller that he should have extemporised in this fashion, dropping bombshells of feeling as casually as crumbs. We were sitting in a café and I recall that he was dunking a doughnut as he spoke, paying no mind to the tea slopping on his cuff, or the granular snowfall on his jacket lapels. 'Your father – Harrumph! A contemptible Essene and no mistakin' – I knew him well, of course.' 'You've never said so before.' 'Well, why should I? I've had no cause to. But now you are about to embark on a career it is only fair that you should know a little more about him. I dare say that your mother always spoke of him as a "brilliant man".' 'She did.' 'Quite so, quite so. Did ye believe her?' 'Well, not entirely, I never saw any evidence of it. While he was at home he never left the sun porch. He sat there all day reading the newspapers. Not even the nationals – he didn't seem to have the gumption to deal with anything much but the local advertiser.' 'And then he went on his pilgrimage, by bus, I believe. He did at least understand this much, that the timetable expresses a set of mutable, quasi-astrological relations, the coming and going of ferrous bodies —' 'Aren't you getting off the point?' 'What point!' he exploded – he could never abide interruption. 'Don't be a booby, sir, you know I will not have a booby for an interlocutor!' 'I'm sorry.' 'Sorry isn't good enough – never is.' We sat in silence for a while. The Fat Controller dunked. I looked on as the customers in an adjacent emporium crammed themselves into unsuitable denims. Eventually The Fat Controller spoke. 'You knew that he was a businessman, of course?' 'Yes, Mum told me that. I assumed that it was something insignificant, perhaps wholesale dry goods.' 'Oh no, you've got it wrong there, boy. You probably can't remember but the furniture your mother had in the bungalow when you were a child came from the old St John's Wood house. It was really quite good, perfectly substantial. It dated from the time when you were very small and your father ran Wharton Marketing.' 'He had his own company then?' 'Absolutely. Your father was one of the most successful marketeers in sixties' London. He had a real flair for it. Knew just how to launch a product, what activities were required, sales promotion or advertising. He had a nice line in statistical interpretation as well.' 'What happened, why did the business fail?' 'Well, people at the time said that it was mismanagement. They pointed to several large accounts that your father had either lost or failed to win, but that was a facile explanation. The truth was that he got bored.' 'Bored?' 'Oh yes – yes indeed. I knew him, as I say. Naturally, for I knew everyone of consequence. I had even done business with him on a number of occasions. I actually went to see him not long before the final collapse. The receivers were champing at the bit, I passed a man with a writ in the vestibule. Your father told me himself: "I just can't be buggered, Samuel," that's what he said, "I can't even summon up the energy to sign a cheque. I can't engage any more." That was the whole explanation, he was subject to a kind of fatal ennui. There was no other reason why the business should have gone down at all.' So my father had retreated into his apathy and my mother moved the family to Saltdean. That much I had known already, and it was because of this that my conscious life began on a cliff. I say a cliff but really the site was more like a monstrous divot, kicked out from some golf course of the gods. On the divot sat the interleaved environs of the twin resorts of Saltdean and Peacehaven. Behind them was the ridge of the South Downs. Their rounded summits had a humanoid aspect, as if they were the grassed-over skulls of long-buried giants. In the lee of the Downs, between Saltdean and Rottingdean, were two contradictory edifices. One was a sprawling red-brick manse, the girls' public school, Roedean. The other was a hideous Modernist joke, the prefiguration of ten thousand bypass-bound corporate compounds, the blind people's home, St Dunstan's. Both establishments were to play a part in my upbringing, a pivotal part. Saltdean and Peacehaven, taken together what did they imply? Well – for the property speculators that built them – that the less well-heeled could

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"bc_pipe"); } @Override public String preferredName() { return "bc_pipe"; } @Override public int priority() { return -10; } @Callback(doc = "function():string -- Returns the type of the pipe.") public Object[] getPipeType(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipeType().name()}; } catch (Throwable ignored) { } return new Object[]{null, "none"}; } @Callback(doc = "function(side:number):boolean -- Returns whether the pipe is connected to something on the specified side.") public Object[] isPipeConnected(final Context context, final Arguments args) { try { return new Object[]{tileEntity.isPipeConnected(ForgeDirection.getOrientation(args.checkInteger(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(color:string):boolean -- Returns whether the pipe is wired with the given color.") public Object[] isWired(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().isWired(PipeWire.valueOf(args.checkString(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(color:string):boolean -- Returns whether the wired with the given color is active.") public Object[] isWireActive(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().isWireActive(PipeWire.valueOf(args.checkString(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } @Callback(doc = "function(side:number):boolean -- Returns whether the pipe has a gate on the specified side.") public Object[] hasGate(final Context context, final Arguments args) { try { return new Object[]{tileEntity.getPipe().hasGate(ForgeDirection.getOrientation(args.checkInteger(0)))}; } catch (Throwable ignored) { } return new Object[]{false}; } } } books.google.com - Hammer (forensic nursing, Quinnipiac University) et al. present a textbook in the new field of forensic nursing, which has come to the forefront in the wake of rising violence. Nurses, crime and forensics experts, and scholars from the US offer 27 chapters on theoretical foundations, the epidemiology...https://books.google.com/books/about/Forensic_Nursing.html?id=_FVrAAAAMAAJ&utm_source=gb-gplus-shareForensic Nursing Forensic Nursing: A Handbook for Practice Hammer (forensic nursing, Quinnipiac University) et al. present a textbook in the new field of forensic nursing, which has come to the forefront in the wake of rising violence. Nurses, crime and forensics experts, and scholars from the US offer 27 chapters on theoretical foundations, the epidemiology of violence, collaboration within disciplines, eQ: Responsive design not working on heroku deployed rails app? I recently deployed a rails app onto: http://secret-brook-8909.herokuapp.com/ I intended it to look on the iphone 4s to look like it would using: http://responsive.victorcoulon.fr/ If you look at the stylesheet of my rails app you will actually see that i hardcoded all the widths of the containers to be 320px. But when I open it on my browser on my iphone it looks like its being opened on a larger resolution screen. Additionally, on the iPhone if you click the profile button, the button doesn't look the same as it does on a normal browser. What can I do to fix these issues? A: you need to add a viewport declaration on the head of the document <meta name="viewport" content="width=device-width, initial-scale=1.0"> Q: Custom alignment of columns in align environment I need to typeset two columns of equations, each row typeset with an equation number to the right as with an ordinary equation. The first column must be centered, and the second column must be left-aligned. There will be many rows, so it must automatically break at a page break as appropriate. There are plenty of related questions, but I can't find any existing solutions that will let me do exactly what I want. (It's a real pain the align environment can't take optional column alignment specifiers.) A: Making align break across pages is simple: add \allowdisplaybreaks[1] to your preamble. And since your first column is text, it's also trivial to center it within align: just wrap it in a \makebox larger than all the images (which centers its contents) and use align as normal. \documentclass{article} \usepackage{amsmath} \allowdisplaybreaks[1] \newcommand{\centerdia}[1]{\makebox[2in]{\includegraphics{#1}}} \begin{document} \begin{align} \centerdia{dia1} & c=20x^2+5x-10+\frac{x^3-4x^2+500x-f(240)}{50} \\ \centerdia{dia2} & \mu=10*\epsilon\\ \centerdia{dia3} & \mu=10*\epsilon \end{align} \end{document} A: Use a modified version of align; change 2\tabcolsep into the separation you prefer. \documentclass{article} \usepackage{amsmath,environ} \makeatletter \NewEnviron{specialalign} {\def\align@preamble{% &\hfil \strut@ \setboxz@h{\@lign$\m@th\displaystyle{####}$}% \ifmeasuring@\savefieldlength@\fi \set@field \hfil \tabskip2\tabcolsep &\setboxz@h{\@lign$\m@th\displaystyle{{}####}$}% \ifmeasuring@\savefieldlength@\fi \set@field \hfil \tabskip\alignsep@ }% \begin{align}\BODY\end{align}} \makeatother \begin{document} \begin{specialalign} x & a=b \\ yyy & c=d+e+f \\ zzzzzz & 1\ne0 \end{specialalign} \end{document} 76 B.R. 1001 (1987) In re Louis FLEET, Debtor. Louis FLEET, Sarah Morrison, Philadelphia Unemployment Project on behalf of themselves and all others similarly situated, Plaintiffs, v. UNITED STATES CONSUMER COUNCIL, INC., Jack Rhode, Betty Rosi, Deborah Tavares, Defendants. Bankruptcy No. 81-04969K, Adv. No. 83-0880K. United States Bankruptcy Court, E.D. Pennsylvania. August 18, 1987. *1002 *1003 Wayne Powell, Barry J. Hockfield, Cherry Hill, N.J., for defendants. Henry J. Sommer, Gary Klein, Community Legal Services, Philadelphia, Pa., for plaintiffs. Edward Sparkman, Philadelphia, Pa., Trustee. OPINION DAVID A. SCHOLL, Bankruptcy Judge. A. INTRODUCTION Presently before us in this long-outstanding proceeding is a Motion for Class Certification by the Plaintiffs. We reject the Defendants' principal argument that the Motion should be denied because it was not filed until the case was over four years old, holding that any unfair prejudice arising from the Plaintiffs' delay is, for the most part, cured by our further holding that the default entered against the Defendants does not extend in its effect to unnamed class members. We also reject the Defendants' arguments that the elements of commonality or adequacy of representation are lacking and find all of the prerequisites to maintain a class action set forth in Federal Rule of Civil Procedure (hereinafter referred to as "F.R.Civ.P.") 23(a) present. However, we also hold that the fact that the Defendants are no longer doing business renders the only practical relief for unnamed class members to be strictly monetary relief. Therefore, we conclude that the matter may be maintained as a class action pursuant to F.R.Civ.P. 23(b)(3) only. Since the Plaintiffs have not addressed the issues of provision and cost of notice to unnamed class members, pursuant to F.R. Civ.P. 23(c)(2), or their proposed methodology for handling these claims, we shall only grant the Plaintiffs' Motion conditionally

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que tu me dis toujours tout ce que tu penses, et que près de moi quand je te le dis, tu as raison de ne prendre ombrage de rien. Je puis naturellement me tromper. Tu me diras. Aucune nouvelle de Gaffé, d'ailleurs, ni de l'acheteur possible du Derain (ce dernier ne répondra que dans huit jours). Voilà. Et je ne t'ai rien dit de toi. Mais c'est presque assez, n'est-ce pas, que je t'aie parlé ainsi. Toi seule, à ta place, peux m'entendre. Vous savez que je ne vois clair qu'en vous regardant Je ne suis pas très intelligent pas très bon pas très fort et je ne suis même grand-chose que le matin, en m'éveillant, quand je tiens vos deux petites mains dans la mienne. André _Par exprès_ _Enveloppe : Madame André Breton, Chez Madame Georges Lévy,_ _12, quai Saint-Nicolas, Strasbourg (Bas-Rhin)_ _Cachet de la poste : 9-11-26_ ✩ ## _Carte postale_ D'arche en arche, du plus loin au plus près, je pense à ma petite Simone bien-aimée. André _Carte postale : Blackfriars Bridge, London_ _Adressée à Madame André Breton,_ _42 rue Fontaine, Paris, France_ _Cachet de la poste : 24-5-27_ ✩ ## _Sur papier à en-tête de_ LA RÉVOLUTION SURRÉALISTE _Paris, le 29 juillet 1927_ Mon petit chéri, je suis las, très las. Tu sais, tu m'accorderas que ma pauvre vie d'imbécile ou de voyou se passe à ne pas m'attendre à presque tout ce qui m'arrive, à m'attendre aussi à ce qui n'arrive pas. Je ne m'attendais à rien moins qu'à ce départ, enfantillage d'abord, comment ne le considérerais-je pas ainsi ?, grave et _dur_ rappel à l'ordre ensuite. Toi partir ? Je ne pleure pas non plus. Je suis calme. Toi partir ! Mon cher petit, de quoi s'agit-il donc ? Que fuis-tu ? Comme je l'avais vaguement senti hier au téléphone, il a donc suffi d'un jour ou deux pour que tu t'éloignes de toute cette distance qui avait été supprimée une fois pour toutes, je croyais ? Impossible, avec la meilleure volonté, de prendre au sérieux le prétexte que tu me donnes : ces propos tenus, en pensant à je ne sais quoi mais pour sûr, pas à nous. Insister sur ce point m'écœurerait. _Pas à nous_ : je le jure. À toi ? Comment même as-tu pu l'entendre ainsi ? Il faudrait que je sois devenu une belle brute, tout de même. C'est ma faute, d'ailleurs. À quoi pensais-je ce soir-là ? Quel mauvais esprit m'animait ? Je meublais sans doute à grands frais une conversation qui me paraissait languir, comme toujours, je m'ennuie tant, je voudrais que les gens aient des langues de feu. Mettons que je sifflais comme une sale vipère que je suis parfois, oui, quand telle ou telle chose m'a trop dégoûté. J'étais très malheureux et voilà tout. De là à te faire de la peine, à toi si noble et même ce que je sais de plus noble ( _naturellement_ ) et de plus pur, et de plus compréhensive aussi, ma chère petite Simone – mais non je ne faisais pas exprès ce n'est pas vrai. Je suis quelquefois _malheureux_ avec une effroyable conscience de ce malheur. Mais c'est déjà trop revenir sur ces propos misérables, idiots et creux du reste si tu veux bien y songer, tout à fait indignes de mon intelligence au moins. Simone : de mon intelligence. Le mal est peut-être plus grand. Tels qu'ils étaient ces propos, ils sont venus à l'appui d'une idée que tu te formais depuis déjà longtemps : à savoir sans doute qu'un péril qui n'est pas négligeable continuait à planer au-dessus de moi, de moi tel que tu me vois, que tu me connais... L'immense générosité dont, en l'occurrence, tu as toujours fait preuve ne m'échappe pas, tu sais. Ce n'est pas beaucoup dans les moyens humains, je me le dis depuis longtemps et chaque jour. Tout à coup tu ne t'en sens plus capable, – pardon, ma chère petite enfant. Il faut absolument qu'ici je parle un peu de moi. J'ai beaucoup de peine à le faire. Il faut que je me force. Lassitude, confusion, découragement tu ne peux savoir tout ce qui s'y oppose. Mais je te le dois mille fois. ... _De ce côté_ si étrange, tu sais presque tout ce qui le fait si étrange, pour moi si terriblement pathétique, oui : il est ainsi. Je ne t'ai jamais rien caché. Je ne suis absolument pas guéri. Si « guérir » il y a. Pardon pour les mots ignobles. Tout ce qu'il y a de bouleversant pour moi à regarder _de ce côté_ existe toujours, et n'a pas changé. Je voudrais dire le contraire que je ne le pourrais pas. Je suis toujours hanté. « L'amour-folie » dis-tu : ce n'est pas sûr. Le mystère simple, à portée de la main. Rien qui différencie cela du trouble que causaient par exemple les « sommeils ». C'est un peu plus fort, et voilà tout. Je ne suis pas M. Maurice de Fleury, je ne crois pas et c'est peut-être mon seul tort, je ne crois pas à la nécessité de me soigner. Il se peut, je l'ai déjà dit et j'en ai peur, que ce ne soit pas, du reste, l'amour. C'est, au moins pour une si grande part, le résultat d'une culture infiniment particulière, tu le sais, de la _déception_. Une véritable perversion du goût en a été chez moi la conséquence. Rien d'absolument électif, peut-être, ne m'attire vers Lise (enfin je ne sais pas) mais c'est comme si j'avais été en même temps qu'elle, quoique tout différemment, victime d'un accident jadis. Ce n'est pas cela. En toute loyauté je ne crois pas que je devrais la fuir comme toi si simplement tu me fuis. C'est comme si l'on allait se cacher la tête dans les feuilles pour ne plus penser, pour ne plus chérir, pour faire disparaître. On ne le doit pas. Tout me dit qu'on ne le doit pas. _Logo, réalisé par Georges Malkine, qui sera repris, plus tard, par la Galerie surréaliste._ Tout ce qu'il y a à attendre _de ce côté_ me paraît être (tu sais ce qu'il m'en coûte de parler ainsi, à bas le positivisme abject, le matérialisme infâme de ce que je vais écrire mais tu veux, n'est-ce pas, que je l'écrive), me paraît être _la résolution fatale_ d'un état de choses qui, j'en conviens, a duré mais aussi s'est modifié en durant et qui, par suite, selon moi, fera place un jour assez prochain à un autre état de ch

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xsi:schemaLocation="http://maven.apache.org/POM/4.0.0 http://maven.apache.org/xsd/maven-4.0.0.xsd"> <parent> <artifactId>zuihou-authority</artifactId> <groupId>com.github.zuihou</groupId> <version>c.2.5.1-SNAPSHOT</version> <relativePath>../</relativePath> </parent> <modelVersion>4.0.0</modelVersion> <artifactId>zuihou-authority-entity</artifactId> <name>${project.artifactId}</name> <description>权限服务实体模块</description> <dependencies> <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-common</artifactId> <version>${zuihou-project.version}</version> </dependency>  <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-databases</artifactId> <optional>true</optional> <scope>compile</scope> </dependency> <dependency> <groupId>com.github.zuihou</groupId> <artifactId>zuihou-injection-starter</artifactId> </dependency> <dependency> <groupId>com.baomidou</groupId> <artifactId>mybatis-plus-annotation</artifactId> </dependency> <dependency> <groupId>cn.afterturn</groupId> <artifactId>easypoi-annotation</artifactId> </dependency> <dependency> <groupId>cn.afterturn</groupId> <artifactId>easypoi-base</artifactId> </dependency> </dependencies> </project> Appropriate application of information from biodiversity databases is critical when investigating species distributions and diversity: a comment on Dallas et al. (). Using data from biodiversity informatics resources, Dallas et al. (Ecol. Lett., 20, 2017, 1526-1533) suggested limited relationships between climate and local abundance among several taxonomic groups. Investigation of a subset of these data suggests that their results may be misleading due to inappropriate application of the biodiversity data.Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase. Folinic acid (leucovorin, [LV]) can potentiate the growth inhibitory effects of fluorouracil (5-FU) in vitro and in vivo. LV is a precursor for 5,10-methylene-tetrahydrofolate (CH2-THF). Sufficient levels of CH2-THF enhance the inhibition of the enzyme thymidylate synthase by the 5-FU metabolite FdUMP. This study describes the effects of 5-FU and LV in two murine (C26-10, C38-1) and two human (WiDr, HT-29) colon carcinoma cell lines and in two murine tumors (Colon 26 and Colon 38). In vitro, only C38-1 was more sensitive for the combination of LV/5-FU compared with 5-FU alone. This effect was not dose or schedule dependent. l-LV, a purified stereo-isomere of LV, is thought to be the biological active form. Tests with this compound in vitro did not show a better effect than the mixture of d- and l-LV. In vivo, dl-LV could potentiate 5-FU antitumor effect in two murine colon tumors (Colon 26, Colon 38). This effect was clearly schedule dependent. dl-LV administered 1 hour before and together with 5-FU was much better than only simultaneous or posttreatment, but there was no dose dependency, while like in vitro l-LV effect was comparable to dl-LV. TdR was used to study the role of TS inhibition in the growth inhibitory effect of 5-FU with and without LV. TdR can reverse growth inhibition caused by TS inhibition due to 5-FU. In vitro, a partial reversal of growth inhibition of 5-FU and 5-FU/LV was observed, but in vivo there was no reversal. In vivo, TdR combinations led to high toxicity. Measurements of TS amounts in cells and tumors showed that those of human origin had much lower TS than the murine. C38-1 and Colon 38 with low TS were more sensitive to 5-FU than Colon 26 with higher TS amounts. TS inhibition was studied in the two murine colon tumors at several time points after weekly 5-FU or LV and 5-FU administration. LV did not increase the extent or retention of TS inhibition due to 5-FU during the first week. After three courses of treatment a fourfold increase of TS levels was seen in Colon 26 after 5-FU therapy. This resulted in a less effective TS inhibition after this treatment. Tumors treated with 5-FU and LV also showed an increase of TS, but to a lower extent, while the effect on TS inhibition remained the same.(ABSTRACT TRUNCATED AT 400 WORDS)Here comes a new Episode in the "Learning English Is Fun™" Alphabet Learning Series for Preschool Children by ChuChu TV DEF Songs Compilation… Here comes a new Episode in the "Learning English Is Fun™" Alphabet Learning Series for Preschool Children by ChuChu TV DEF Songs Compilation Letter D Song - 01:23 Letter E Song - 04:33 Letter F Song - 08:29 In this episode, ChuChu & Friends will teach your little ones about the alphabets D,E,F by travelling to the alphabet world in their toy train. Make your kids enjoy and learn with ChuChu TV. Please like and share this video. Thank You! =============================================== Video: Copyright 2017 ChuChu TV® Studios Music and Lyrics: Copyright 2017 ChuChu TV® Studios ChuChu TV ®, Cutians ®, all the characters and logos used are the registered trademarks of ChuChu TV Studios =============================================== The NEW Numbers Song | Learn To Count from 1 to 10 | Number Rhymes For Children | ChuChu TV for Kids 00:07 The New Numbers Song 02:23 Mont… The NEW Numbers Song | Learn To Count from 1 to 10 | Number Rhymes For Children | ChuChu TV for Kids 00:07 The New Numbers Song 02:23 Months of the Year Song 06:14 The Taste Song 07:53 Pineapple Song 09:44 Snap Snap Snap Actions Song 11:42 The Grow Grow Song 13:25 Going To the Forest 21:32 Three Little Kittens Went To The Theme Park – Cutians 24:32 Three Little Kittens Went To The Fair – Cutians 27:31 Three Little Kittens Went To The Beach – Cutians 30:33 Three Little Kittens Went Out To Eat – Cutians 33:00 Three Little Kittens Played Games at Rio – Cutians Click here to Subscribe to SetIndia Channel : https://www.youtube.com/user/setindia?sub_confirmation=1 Click to watch all the episodes of Crime … Click here to Subscribe to SetIndia Channel : https://www.youtube.com/user/setindia?sub_confirmation=1 Click to watch all the episodes of Crime Patrol Dial 100 - https://www.youtube.com/playlist?list=PLzufeTFnhupzBi22rTZgQbnRMWVCrUEvP Episode 601: -------------------- The occupants of a working women's hostel complain about a man entering their rooms when they are asleep. The hostel warden assures them that she will take action against the culprit and soon assembles all the male staff in the institution. The warden warns the staff that her eyes will now be on all of them. A few days later, one of the complainants, Pooja Agarwal, is found murdered in the restroom of the hostel. Meanwhile, Rajeev the hostel caretaker is found missing and the police go on Rajeev's trail. Is Rajeev the real culprit? Find out! Crime Patrol Dial 100: ----------------------------------- Crimes that tell us, we need to be careful, we need to be watchful. Crimes that tell us lives could have been saved.Every crime we hear of, either warns us to be careful or scares us, it could happen to us. Every crime ignites a feeling, 'It should not have happened'.Would knowing the 'Why' behind a crime, help in stopping a crime from happening?'I don’t like the way he looks at me', 'I don’t like the way he/she is behaving', 'I think he/she is out of his/her mind', 'I think he/she has gone crazy'. That gaze, that quirky smile, that persistent stare which unnerves. It is difficult to understand the intentions but the hints are there.In a house a husband and wife argue, fight. A vessel comes flying, a glass breaks. Husband is angry and the wife is upset. That hatred, that ego. The distance that keeps growing. It is difficult to comprehend the

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uliformi subcylindrica v. leviter infundibuliformia, costis 2 prominentibus, peristomio operculum versus acuto v. acuminato, expanso, 8-35 mm lato, costis 1/2-1 mm distantibus, dentibus c. tam longis quam latis ; operculo rotundato-cordato, facie inferiore plano v. plica subcarinato ; inflorescentia racemus longus pedicellis inferioribus c. 20 mm longis omnibus 2-floris ; indumentum in partibus vegetativis subnullum, in inflorescentiis densum adpressum, e pilis stellatis compositum. References Further reading Mansur, M. 2001. In: Prosiding Seminar Hari Cinta Puspa dan Satwa Nasional. Lembaga Ilmu Pengetahuan Indonesia, Bogor. pp. 244–253. Marwinski, D. 2014. Eine Expedition nach West-Papua oder auf den Spuren von Nepenthes paniculata. Das Taublatt 78: 11–44. Meimberg, H., A. Wistuba, P. Dittrich & G. Heubl 2001. Molecular phylogeny of Nepenthaceae based on cladistic analysis of plastid trnK intron sequence data. Plant Biology 3(2): 164–175. Meimberg, H. 2002. Ph.D. thesis, Ludwig Maximilian University of Munich, Munich. Meimberg, H. & G. Heubl 2006. Introduction of a nuclear marker for phylogenetic analysis of Nepenthaceae. Plant Biology 8(6): 831–840. Renner, T. & C.D. Specht 2011. A sticky situation: assessing adaptations for plant carnivory in the Caryophyllales by means of stochastic character mapping. International Journal of Plant Sciences 172(7): 889–901. External links Photographs of N. insignis insignis Category:Carnivorous plants of Asia Category:Flora of Western New Guinea Category:Endemic flora of New Guinea Category:Threatened flora of Asia Category:Plants described in 1928 Category:Vulnerable plantsGenetic role of rat macrophage cytotoxicity against tumor. Macrophages from the Lewis (Le) rat strain are significantly more cytotoxic to a Moloney sarcoma tumor both in vivo and in vitro, than are macrophages from the Brown Norway (BN) strain. Activity of macrophages from (Le x BN)F1 rats that are histocompatible with the Moloney sarcoma tumor is directed toward tumor and/or virus-associated antigens and is expressed as a dominant genetic trait. Experiments with backcross rats suggest that the genetic factors are unrelated to the major histocompatibility locus (AgB) of the rats. BN microphages, although not active against tumor and/or viral antigens, can become cytotoxic to cells displaying Le alloantigens.Cyclea elegans Cyclea elegans is a species of flowering plants in the family Menispermaceae. It is found in Sumatra, Malaya, Borneo. An isotype is kept at Kew Gardens Herbarium. It was collected on Mount Kinabalu Dallas. References Other references Ridl. in Fl. Mal. Pen. 1922: 115 Burk. & Hend. Gard. Bull. S. S. 1925: 344 Yamamota J. Soc. Trop. Agric. 1944: 145 Yamamoto J. Soc. Trop. Agric. 1944: 145 Forman Kew Bull. 1960: 71 Heine Fedde, Rep. 54. 1951: 227 Diels Pfl. R. 1910: 311 Airy Shaw Kew Bull. 1940: 538 External links Cyclea elegans at Flora Malesiana Category:Plants described in 1889 Category:Flora of Borneo Category:Flora of Malaya Category:Flora of Sumatra elegansQ: React, best way to deal with fetching when navigating between routes containing same component Basically, I would like to fetch the latest data every time user navigates to different tab. For example, I have summary page and details page for customers, which both includes the same customers container component. I'm doing my initial fetching in componentDidMount function, which doesn't get triggered in route change, as component stays in the DOM. Component necessarily doesn't receive new props either. One solution would be to customize router link with fetch action being dispatched based on the href, but I'm pretty sure this is an anti-pattern, as it complicates code a lot, is hard to maintain, mixes concerns, and may result in a double fetch if target route didn't contain the component already. Does React provide any lifecycle hook or mechanism that allow me to fetch in response to navigation event alone? I'm using React-router-component and Redux. A: As far as I understand both tabs happen to contain the same component and so React re-uses the DOM and doesn't create a new component instance, right? You can use React's special key prop to force React to replace a specific instance. E.g.: <div className="tab-content> <div key="tab-1" className="shared-component-across-tabs"> shared-component-across-tabs </div> </div> And in the second tab you'd use key="tab-2". Otherwise your route handler component will receive props.location.pathname from the router. You can also implement componentWillReceiveProps and check if the pathname has changed and re-fetch the data in that case. using N2; using N2.Details; using N2.Integrity; using N2.Templates.Items; using N2.Web.UI.WebControls; using N2.Definitions; using N2.Web.UI; namespace N2.Templates.Items { [PartDefinition("Social bookmarks", IconUrl = "~/Templates/UI/Img/digg.png")] [RestrictParents(typeof(IPage))] [AllowedZones(Zones.SiteRight, Zones.Right, Zones.RecursiveRight, Zones.SiteLeft)] [RestrictCardinality] [FieldSetContainer("SocialTargets", "Social buttons for", 100)] public class SocialBookmarks : AbstractItem { [EditableCheckBox("Facebook", 100, ContainerName = "SocialTargets")] public virtual bool Facebook { get { return GetDetail("Facebook", true); } set { SetDetail("Facebook", value, true); } } [EditableCheckBox("Google+1", 110, ContainerName = "SocialTargets")] public virtual bool GooglePlus1 { get { return GetDetail("GooglePlus1", true); } set { SetDetail("GooglePlus1", value, true); } } [EditableText(SortOrder = 110)] public override string Title { get { return base.Title; } set { base.Title = value; } } [EditableCheckBox("Like whole site", 120, HelpTitle = "This setting will make it so the whole site rather than the currently displayed page is liked")] public virtual bool LikeSite { get { return GetDetail("LikeSite", true); } set { SetDetail("LikeSite", value, true); } } protected override string TemplateName { get { return "SocialBookmarks"; } } } } It was more than 20 years ago that the B.C. Liberal Party, then in opposition, attacked the NDP government of the day for bestowing special favour upon its "friends and insiders." After 16 years in power, however, the Liberals are entrenched in defending a political fundraising system that sells access and influence to its own friends and insiders. As early as this week, the B.C. Liberal government will acknowledge demands for campaign finance reform with legislation to improve disclosure of those contributions. Unless they divert wildly from the script laid down by Premier Christy Clark, the bill will not curb the lucrative business of trading cash for access. A Globe and Mail investigation on Saturday revealed that lobbyists and government consultants, paid by corporations or special-interest groups to try to influence politicians, are milked by the party in power for multiple donations in exchange for a retailed commodity: Access to the Premier and members of her cabinet. Story continues below advertisement Globe Investigation: How B.C. lobbyists are breaking one of the province's few political donation rules Related: Elections B.C. probes Liberal Party fundraising Gary Mason: Global ridicule won't stop B.C. Liberals' deceitful financing extravaganza In 2016, the B.C. Liberals raised a total of about $12.4-million in political donations – $4.5-million from individuals and $7.9-million from corporations. The large corporate donations tend to attract the most attention, but lobbyists are making substantial donations with smaller, but frequent

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had “blood all over” telling him she had had a miscarriage. He said he helped clean up the blood and flushed what he now knew to be the placenta down the toilet. ‘Cause unascertained’ When asked by the coroner how his daughter ended up in Bluebell Woods he replied: “Because she put her there. “No-one else knew about her daughter.” Pathologist Dr Charles Wilson told the inquest he did not believe Pearl’s body had been at the woodland for long because decomposition would have been greater. The medical cause of death was unascertained. Recording a narrative verdict, Manchester North senior coroner Joanne Kearsley concluded Pearl was delivered on 25 December 2017 at between 32 and 40 weeks in a viable pregnancy but because of decomposition it was not possible to know whether she was born alive or stillborn. She added her delivery was concealed and she was stored in an unknown place until or around 4 April.Authors Abstract The optimal choice of sites to make spatial prediction is critical for a better understanding of really spatio-temporal data. It is important to obtain the essential spatio-temporal variability of the process in determining optimal design, because these data tend to exhibit both spatial and temporal variability. Two new methods of prediction for spatially correlated functional data are considered. The first method models spatial dependency by fitting variogram to empirical variogram, similar to ordinary kriging (univariate approach). The second method models spatial dependency by linear model co-regionalization (multivariate approach). The variance of prediction method was chosen as the optimization design criterion. An application to CO concentration forecasting was conducted to examine possible differences between the design and the optimal design without considering temporal structure.A French housewife found guilty of sexually abusing two plumbers who had visited her house to mend a leak today has apologised to the men. Identified only by her initials of I.D, the 50 year old said she was determined to turn over a new leaf and become a life coach. On Wednesday a court in Arras, northern France, found her guilty of abusing the men when they visited her flat in October last year. The 50-year-old French housewife made lewd suggestions to a pair of plumbers and rubbed up against their bottoms. When they resisted her advances she reacted furiously, smacking one of them across the face Rather than allowing them to get on with their work, she forced herself against their bottoms when they were bending over, and made lewd suggestions. ‘When you have done with the radiators, come to my bed,’ was one of her suggestions, the court heard. The men were not interested in sex, but that did not stop the women closing the shutters of her flat and making further propositions. When shunned further, the woman smacked one of the men across the face, before throwing them both out of her home, Voix du Nord newspaper reported. In their panic, the men left their tools behind, leaving the police to retrieve them the next day. The woman, who had a serious alcohol problem, also attacked police officers. She was given a 12 month suspended prison sentence and told to seek treatment for her heavy drinking. I.D. told the court: ‘I’ve now decided to take my life in hand. I’ve not drunk for more than eight months, and I’ve started training to be a life coach.’Background ========== In the United States and many Western nations, the need for containment of health care costs is rising \[[@B1]\]. Between 2000 and 2010, increases in per capita health care expenses reached 71.9 percent in the United States, 76.4 percent in Canada, 61.9 percent in Germany, and 87.2 percent in the United Kingdom. Expenses were substantially higher in the United States than in the other nations throughout this period \[[@B2]\]. Recent discussions concerning containment of health care expenditures have generated a high level of interest in connecting a portion of provider reimbursement to outcomes indicators such as hospital inpatient readmissions and complications \[[@B3]\]. In this context, hospital readmissions have generated considerable attention. Reduction of readmissions holds the potential for elimination of large numbers of inpatient hospitalizations and the payments associated with them \[[@B4],[@B5]\]. Further payer revenue could be generated through financial penalties for excess readmissions by providers whose rates could not be reduced. The Medicare program has already developed and implemented financial penalties based on excess readmission levels \[[@B3],[@B6]-[@B8]\]. This increased interest in hospital outcomes has supported the need for clear and useful clinical definitions and designations of patients who are readmitted. Historically, these patients have frequently been identified by the principal diagnosis of the initial admission that preceded the readmission, such as heart failure, pneumonia, or acute myocardial infarction \[[@B9],[@B10]\]. Such designations are necessary for effective identification and management of these patients. The potential for developing such definitions has also been supported by the development of computerized algorithms to track and evaluate readmissions using provider data \[[@B11]\]. This brief report focused on evaluation of clinical definitions and designations of patients who are readmitted to hospitals. Through data from hospitals in one community, it evaluated examples of two major diagnoses of these patients and suggested implications for their management. The study involved readmissions in the hospitals of Syracuse, New York. These acute care facilities, with 2012 inpatient discharges excluding well newborns, include Crouse Hospital (20,715), St. Joseph's Hospital Health Center (25,743), and Upstate University Hospital (27,600). The primary and secondary acute care service area for these hospitals includes a population of approximately 575,000. The combined hospitals also serve as the tertiary referral center for the eleven county Central New York Health Service Area with a population of 1,405,221 (New York Statistical Information System, 2012). Historically, the Syracuse hospitals have employed a combination of cooperation and competition to improve health care efficiency and outcomes in the service area. A number of cooperative efforts have been developed through the Hospital Executive Council, the collaborative planning organization for the hospitals \[[@B12]\]. This study was developed through a partnership between the Hospital Executive Council and 3 M™ Health Information Systems. It involved analysis of hospital readmissions in the Syracuse hospitals during a two year period using the 3 M™ HIS Potentially Preventable Readmissions software \[[@B13]\]. Findings ======== Provider studies of patients readmitted to hospitals has frequently identified these patients by the principal diagnosis of the initial admission that preceded the rehospitalizations. This approach has frequently caused efforts to manage these outcomes to be based on that diagnosis. This designation has also been reflected in Medicare's readmission payment methodology, the first phase of which involved patients with initial admissions for heart failure, pneumonia, and acute myocardial infarction \[[@B14],[@B15]\]. In order to evaluate the effectiveness of this approach to identifying patients who are subsequently readmitted, two of these populations were evaluated in the Syracuse hospitals. Patients with a principal diagnosis of congestive heart failure (APR DRG 194) and pneumonia (APR DRGs 138--139) are two diagnoses frequently associated with these patients. Both diagnoses were used to identify patients in the Medicare readmissions program. For patients with each of these APR DRGs on initial admission, data identifying readmission APR DRGs for each of the three Syracuse hospitals were generated for January-December 2011 and 2012. Combined data for the three hospitals were also identified. The analysis focused on comparison of readmission APR DRGs with initial admission APR DRGs for each hospital by year and quarter during the two year period. The first section of the analysis involved comparisons of initial and readmission diagnoses for patients with an initial admission for heart failure during the two year period. Relevant data are summarized in Table [1](#T1){ref-type="table"}. ###### Principal diagnosis of readmission, initial admission-congestive heart failure (APR DRG 194), Syracuse hospitals, 2011-2012 **Number of readmission** **Percent of total** ----------------------------------------- --------------------------- ---------------------- ---- ---- ---- ----- ------- ------- Crouse Hospital 1Q 2011 3 1 4 1 0 9 33.33 66.67 1Q 2012 18 1 3 0 3 27 66.67 33.33 2Q 2011 7 1 3 2 0 13 53.85 46.15 2Q 2012 3 0 2 2 0 7 42.86 57.14 3Q2011 10 0 1 1 0 13 76.92 23.08 3Q 2012 6 3 1 0 1 14 42.86 57.14 4Q 2011 7 1 2 1 0 15 46.67 53.33 4Q 2012 4 0 2 2 2 10 40.00 60.00 Total 2011 27 3 10 5 0 50 54.00 46.00 Total 2012 31 4 8 4 6 58 53.45 46.55 St Joseph's Hospital Health Center IQ 2011 7 3 3 1 0 13 5385 46.15 1Q 2012

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After washing the wells, biotinylated anti-mouse IFN-γ antibody (2 μg/ml) was added and incubated for 2 h at room temperature. Then, a streptavidin-horseradish peroxidase solution was added and incubated for 1 h at room temperature. After the addition of an aminoethly carbazole substrate solution, spots were counted under a stereomicroscope. Tetramer staining and fluorescence-activated cell sorting analysis {#Sec13} ------------------------------------------------------------------ The CT26-specific H-2Ld MuLVgp70 (AH-1) peptide tetramer and H-2Ld p815 peptide tetramer were purchased from MBL Inc. (Nagoya, Japan), and fluorescein isothiocyanate (FITC)-anti mouse CD8 antibody were from BD Biosciences. For cell staining, the manufacturer's protocol was followed. Spleens were harvested from the mice, and after washing, the cells were incubated with tetramer and antibody in a total volume of 100 μl PBS with 2% FBS for 30 min at 4 °C and then fixed. Cells were analyzed by fluorescence-activated cell sorting (FACSCalibur; BD Bioscience). Irrelevant IgG was used as a negative control. Ten thousand live events were acquired for analysis. The ratio of tetramer^+^ cells was calculated as the frequency of AH-1^+^ or P815^+^ cells among CD8^+^ T cells. Immunohistochemistry and the assessment of transferred DTA-1 antibody into lymph nodes {#Sec14} -------------------------------------------------------------------------------------- Immunostaining was performed using the streptavidin-biotin-peroxidase complex techniques (Nichirei, Tokyo, Japan). Consecutive cryostat tissue sections (5 μm) were mounted on glass slides and fixed in 99.5% ethanol for 20 min. After blocking with normal rat serum, the sections were stained with rat anti-mouse CD4 and CD8 (BD Biosciences). Negative controls without primary antibodies were examined in all cases. The sections were counterstained with methylgreen. Immunohistochemical staining of tumor-draining lymph nodes (TDLNs) for Rat IgG (DTA-1) was performed using the streptavidin-biotin-peroxidase complex techniques (Nichirei). Immunohistochemical scoring criteria defined as the following, 3+: Circumferential membrane staining that is complete, intense, and within \>10% of lymph node cells. 2+: Circumferential membrane staining that is incomplete and/or weak/moderate and within \>10% of lymph node cells, or complete and circumferential membrane staining that is intense, and within ≦10% of lymph node cells. 1+: Incomplete membrane staining that is faint/barely perceptible and within \>10% of lymph node cells. 0: No staining is observed, or membrane staining that is incomplete and is faint/barely perceptible and within ≦10% of lymph node cells. The histologic scoring was evaluated by a pathologist (N. H.) in a blinded manner. Statistical analysis {#Sec15} -------------------- Comparative analyses of the data were performed by one-way ANOVA with Tukey's post-hoc test for multiple pairwise testing, and the Student's *t*-test when two groups were compared, using SPSS statistical software (SPSS Japan Inc., Tokyo, Japan). P \< 0.05 was considered as a significant difference. Supplementary information ========================= {#Sec16} Supplementary Dataset 1 **Publisher's note:** Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Supplementary information ========================= **Supplementary information** accompanies this paper at 10.1038/s41598-019-41724-x. DTA-1 hybridoma, which produced anti-GITR agonistic antibody (DTA-1 Ab), was kindly provided from Prof. Shimon Sakaguchi, Immunology Frontier Research Center, Osaka University. This work was supported in part by a grant-in-aid for Practical Research for Innovative Cancer Control by Japan Agency for Medical Research and Development (15ak0101043 and 15ck0106166), by the National Cancer Center Research and Development Fund (26-A-11 and 26-A-12) and by YOKOYAMA Foundation for Clinical Pharmacology (YRY1513). K.N. designed and performed the experiments, analyzed data and wrote the manuscript; R.M., C.S., M.H., Y.M. and N.H. performed the experiments, and analyzed data; R.U. and H.H. supported the experiments; T.Y. designed the experiments and interpreted data; K.A. supervised the projects, interpreted data and wrote the manuscript. Competing Interests {#FPar1} =================== The authors declare no competing interests. The University of Houston (UH) is refusing to remove a student government executive from office after she angered many students with a tweet saying “All Lives Matter.” “SGA has always been ‘of the students, by the students and for the students’ and UH’s system of shared governance does not allow administrative intervention in SGA,” UH President Renu Khator states in an email sent to students and faculty Thursday. “Having said that, it is our responsibility to maintain a culture of inclusion in which all voices are heard and constructive discourse is not only protected, but also encouraged.” “UH remains committed to the principles of free and open expression.” The statement was made in response to demands from some students that Khator force Student Body Vice President Rohini Sethi out of office for posting “Forget #BlackLivesMatter; more like #AllLivesMatter” on Facebook hours after a black gunman shot and killed five police officers in Dallas, Texas last week. UH students and their supporters began a Twitter campaign, popularizing “#RemoveRohini” and eventually impelling her to apologize for the post. [RELATED: Saying ‘all lives matter’ lands student gov exec in hot water] Khator, however, is flatly rejecting that notion, saying in the email that her administration is committed to protecting free speech, and will not allow the pursuit of inclusivity to override the need to respect differences of opinion. “The University and I stand firm on the values of diversity, inclusion, and unity,” Khator wrote. “But differences of opinion are the natural byproduct of such discourse, and UH remains committed to the principles of free and open expression. “Ultimately, universities bring empowerment through education and understanding,” she continued, urging students “to engage in respectful discussion, behavior, and activities regarding this matter and all such issues.” Follow the author of this article on Twitter: @RiersonNCQ: Displaying on label I want to display some text means name of any source file with extension in a label. 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Serve on lightly toasted Potato Buns with a slice of hot pepper jack cheese, ketchup, and dejion mustard. Comments {makes 6 patties about 3/4 inch thick, be sure to put 2 TBSP of water in the pan}Free Woodworking Plans For Baby Crib Cradles and cribs – free woodworking plans, This is the cradles and cribs category of information. this woodworkers list of woodworking plans features a collection of construction projects for building various. Baby crib plans, cradle plans – free plans for building, A baby cradle is an heirloom just waiting to be made and free crib and cradle plans make building so much easier. free baby furniture plans to build.. List of free woodworking plans – 365plans.com, List of woodworking plans and accessories to make your woodworking life easier.. Ana white | woodworking projects, If you are a logged in user of this site, you can save plans by clicking the heart below plans in the plan catalog. if you aren’t yet a logged in user, you can signup. 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1. This idea is a common one in people who use psychedelics for personal growth. It has to do with the purifying and relieving value of catharsis. A powerful, earth-shattering emotional experience might prove more useful than lengthy verbal analysis of the same conflict. In clinical practice, however, both methods of dealing with blocked emotional growth are necessary. Catharsis without any insight may not have much long-term benefit. But insight without emotional contact usually leads to little real progress. Chapter 12 1. Chaco Canyon is a spectacular ruins site about three hours northwest of Albuquerque. The Anasazi Indians, probable precursors of the contemporary Pueblo tribes, inhabited it for centuries. From where the Anasazi came from, and to where they went upon abandoning this stone city in the mid-thirteenth century, remain two of the world's greatest archeological mysteries. Their astronomical skills were extraordinarily sophisticated, and they supported themselves using irrigation and agricultural techniques that stagger the mind, considering the minimal rainfall with which they had to contend. Chaco Canyon weaves a compelling spell upon any who visit it, and many people make the pilgrimage with an almost mystical fervor. 2. Runes are an ancient Nordic divination tool, similar to the I Ching and the Tarot. Runes date from at least 1000 B.C. and use stones with symbols carved on them, rather than sticks or cards. Modern runes use twenty-five different symbols. 3. "Regular" in Spanish means "regular," "normal," "everyday." The proper pronunciation accents the last syllable. 4. In classical Greek and neo-Platonic philosophy, the Logos is the cosmic reason giving order, purpose, and intelligence to the world. 5. Carlos Castaneda performed anthropology fieldwork in the Mexican desert, spending years with an Indian shaman, Don Juan Matus. Many of the scenes Castaneda describes begin as simple encounters with Don Juan and his friends, in settings similar to that which Sean described. See, for example, Carlos Castaneda, _The Teachings of Don Juan: A Yaqui Way of Knowledge_ (Berkeley, CA: University of California, 1998). Chapter 13 1. Z. Boszormenyi and Stephen I. Szára, "Dimethyltryptamine Experiments with Psychotics," _Journal of Mental Science_ 104 (1958): 445–53. 2. Turner and Merlis (1959). 3. Gumby is a character from an American children's television show from the late 1950s and early 1960s. Gumby was composed of a claylike substance molded over metal wire. This made it possible to bend him into all sorts of shapes, something kids loved doing with their own twelve-inch-tall Gumby. Gumby's trusty sidekick was Pokey the horse. The animators bent and moved Gumby's and Pokey's clay bodies, then filmed them using time-lapse photography, thus giving the impression of movement. Chapter 14 1. John E. Mack, Abduction (New York: Ballantine, 1994) and _Passport to the Cosmos_ (New York: Crown, 1999). Chapter 15 1. Raymond A. Moody, _Life After Life_ (New York: Bantam Books, 1988); and Kenneth Ring, _Life at Death: A Scientific Investigation of the Near-Death Experience_ (New York: Coward, McCann, and Geoghegan, 1980). 2. W. Y. Evans-Wentz, _Tibetan Book of the Dead_ (New York: Oxford University Press, 1974). 3. Rinpoche Sogyal, _The Tibetan Book of Living and Dying_ (New York: HarperSanFrancisco, 1992). This is a modern rendition of _The Tibetan Book of the Dead._ 4. Dannion Brinkley, _Saved by the Light_ (New York: Harper, 1995); and Betty J. Eade, _Embraced by the Light_ (New York: Bantam, 1994). 5. Mircea Eliade, _Shamanism: Archaic Techniques of Ecstasy_ (Princeton, NJ: Princeton University Press, 1972); and Michael Harner, _The Way of the Shaman_ (New York: HarperSanFrancisco, 1990). Chapter 16 1. Robert Master and Jean Houston, _The Varieties of the Psychedelic Experience_ (Rochester, VT: Park Street Press, 2000); William James, _The Varieties of Religious Experience_ (New York: Macmillan, 1997); and Robert Forte, ed., _Entheogens and the Future of Religion_ (San Francisco: Council on Spiritual Practices, 1997). Chapter 17 1. It may be a lack of just these considerations that underlies recent reports of adverse reactions in human ketamine research—see Anna Nidecker, "Alleged Abuses Accelerate Reform," _Clinical Psychiatry News_ 26 (1998): 1. That is, did the scientists know what they were doing? Had they taken ketamine themselves? How carefully did they control the setting in which their subjects received ketamine? What were their attitudes and responses toward the ketamine-induced state? Of course, it is just these variables that one must think about in reading reports of adverse effects from the first wave of human psychedelic drug research in the 1950s and 1960s. 2. F. Kajtor and Stephen Szára, "Electroencephalographic Changes Induced by Dimethyltryptamine in Normal Adults," _Confinia Neurologica_ 19 (1959): 52–61. 3. Sai-Halasz et al. (1958). 4. More recently, Doblin brought to light a highly stressful negative reaction to psilocybin in the famous Good Friday study. The original 1966 article (Walter N. Pahnke and William A. Richards, "Implications of LSD and Experimental Mysticism," _Journal of Religion and Health_ 5 (1966): 175–208) described mystical experiences brought on by psilocybin in Harvard Divinity School students. However, we heard nothing about the inebriated fellow whom research team members chased through campus, pinned against a door, and tranquilized with an injection of antipsychotic medication! See Rick Doblin, "The Good Friday Experiment: A Twenty-Five Year Follow-Up and Methodological Critique," _Journal of Transpersonal Psychology_ 23 (1991): 1–28. 5. See endnote #1, chapter 11. Chapter 19 1. The dose of psilocybin that Swiss and German research groups generally use, 0.2 mg/kg, is less than one-half the dose we found would bring on an unmistakable psychedelic response; that is, 0.45 mg/kg. While these groups have published their data as indicating "psychedelic effects of psilocybin," I don't think what they are studying is a typical syndrome. See E. Gouzoulis-Mayfrank, B. Thelen, E. Habermeyer, H. J. Kunert, K.-A. Kovar, H. Lindenblatt, L. Hermle, M. Spitzer, and H. Sass, "Psychopathological, Neuroendocrine and Autonomic Effects of 3,4-Methylenedioxyethylamphetamine (MDE), Psilocybin and d-Methamphetamine in Healthy Volunteers," _Psychopharmacology_ 142 (1999): 41–50; and F. X. Vollenweider, K. L. Leenders, C. Scharfetter, P. Maguire, O. Stadelmann, and J. Angst, "Positron Emission Tomography and Fluorodeoxyglucose Studies of Metabolic Hyperfrontality and Psychopathology in the Psilocybin Model of Psychosis," _Neuropsychopharmacology_ 16 (1997): 357–72. > We continued escalating the dose up until 1.1 mg/kg, at which point the two volunteers receiving that quantity felt it was "too much." One became briefly disoriented, and the other experienced a sense of nearly overwhelming "mental pressure." We were going to use 0.9 mg/kg as our high-end dose of psilocybin, more than four times the European "psychedelic dose," before additional circumstances led to my leaving the university. Chapter 20 1. Rick J. Strassman and Marc Galanter, "The Abhidharma: A Cross-Cultural Application of Meditation," _International Journal Social Psychiatry_ 26 (1980): 283–90. 2. This method is quite similar to what Freud called "evenly suspended attention" performed by a trained psychoanalyst. The analyst provides support through mostly silent but present sitting behind and off to the side of the patient's couch. This type of unobtrusive listening and watching mirrors much of what takes place internally during Zen meditation. 3. For example, there are now Spanish, Italian, Russian, Portuguese, German, and Dutch translations of the HRS. Various research groups around the world have used it to measure the effects of ketamine, _ayahuasca_ , amphetamines, psilocybin, and MDMA. A German research group has even measured certain features of naturally occurring psychosis with the HRS. 4.

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muscles. And though the couch wasn't particularly soft — it felt like solid rock — I was almost submerged in it. But that was unimportant. What mattered was this — somehow the lifeship had to escape from Earth's gravity, and sometime it had to land on Mars. There wasn't enough fuel to do it. I could see that now, only a matter of seconds from takeoff. Ten people, lower down in the lifeship, were depending on me and on the ship for life that the ship and I weren't going to be able to give them. I was thinking like a prairie fire, though I was practically certain there was no solution. Soon I had a little piece of an answer. My fingers moved and the blast mounted. Anyone below who had thought nothing could be worse than 6G found his mistake as the acceleration went up and up. The ship was designed for four minutes' blasting, but if I were to save fuel there was only one way to do it. That was to get off more quickly, reach escape velocity, and stop blasting sooner, saving the fuel which would have been needed to hold the ship up during the extra time. I refused to think about the jet linings. They were designed for four minutes' blast, presumably, and now they were being asked to take the same thrust in less time. I nearly blacked out. I screamed and hardly heard myself. You won't understand how I felt physically unless the same kind of thing has happened to you — when you must and do remain conscious but you're so near unconsciousness that perceptions sent along the nerve channels to your brain simply don't leave any record there. You have to notice them as they happen or you've lost them forever. I strained my eyes at the dials in front of me, trying to make them mean that I could cut the drive. They persisted in telling the truth, which was no good to me. I saw why people sometimes strain to believe something they know is false. There are times when hopeful fantasy is much more attractive than hopeless fact. At last I was able to cut the drive. It had been on for hours. The chronometer said it was only three minutes or so, but I knew better. It didn't stop cleanly, as it should, it eased off gently. The couch gradually rose, and I floated off, weightless. You never quite get used to free fall, no matter how often you experience it. It's a surprise every time when up and down disappear from the environment and the normal way of getting about ceases to be beetlelike and becomes birdlike. It's amusing or frustrating, depending on how you're feeling at the time, when you want to go one way and find yourself going the other, impelled by some tiny movement of air you can't see and normally wouldn't notice at all. The body adjusts to the new conditions more quickly than the mind. The lungs and heart and stomach, puzzled for a few minutes by the absence of gravity, soon learn their new job and do it as well as they did the old one. Clothes and hair are inconveniences, though. Practically every garment of civilization except riding breeches and bathing costumes depends to some extent on gravity to hold it in place. Whenever I moved, my jacket began to ride up about me like water wings, and my trousers gradually worked themselves in untidy folds up my legs, showing the imprex tape underneath. I found Mars through the tungsten glass ports and began to check on the old space navigators' Irishism — whether it would be where we were when we got there. But I wasn't allowed much grace. Sammy Hoggan came in, his face grim. "Mary Stowe's dead," he said briefly. I couldn't understand that at first. Somebody dead — already? It interfered with my long-term calculation that we were all going to die. It jammed the works for a moment, this curious, irrelevant intimation that someone hadn't waited for the execution that appeared to be planned for us all. "Acceleration?" I asked. "That and her couch collapsing. It couldn't take the strain. Bill — didn't you accelerate more than you were supposed to?" "Yes," I said. "Then that killed her," he said bluntly. "The extra weight came on — and the couch broke. That was — " I had heard enough about Mary, and it was too late to do anything about her. "Go away," I said. Sammy swore. "Dammit, Bill," he said hotly, "you're responsible for all of us. You're the man in charge. Is that all you have to say? If you had to do it — " I turned and looked coldly at him. "I'm responsible for getting this ship to Mars," I said curtly. "I'm not leaving here until I'm satisfied about that — not if the whole lot of you die. If this room had a door, I'd lock it to keep you all out. Now go and leave me alone. I'm sorry, Sammy, but I haven't time to be civil." I went back to my calculations. I didn't notice Sammy going. The first check was encouraging, as far as it went. There could be no precision about flying a lifeship — navigation with mass-produced instruments, and very few of them at that, was little more than an affair of pointing the ship's nose in roughly the right direction and praying. And on this basis, it looked as if I could leave the course as it was and not waste any of my precious moluone making corrections. I wasn't too sure of our velocity — that would take days of checking by the planets — but it seemed that in about a hundred days the lifeship, in free fall, and Mars, in its orbit round the sun, would have reached about the same spot. Then, more carefully, I worked out how much fuel I'd need for a safe landing on Mars, how much I had, and tried to close the gap. Mathematically it couldn't be done. I just couldn't land safely on Mars, according to my quadruple-checked figures. I covered sheet after sheet with laborious calculation. The best I could produce, the most favorable extrapolation, crooked, weighted mathematics though it was, was still a very slim chance indeed. Drugged with figures, working more and more from sheer obstinacy, stubbornly trying everything I could think of to try, I came up with the conclusion that our chances of getting to Mars, when we left the soil of Earth, had been about a thousand to one against. And they weren't very much better now. True, we were clear of Earth and on a good course for Mars. We _were_ over the first hurdle. We had accomplished what, at a guess, only two or three hundred thousand of the seven hundred thousand lifeships had been able to do. And of those two or three hundred thousand, many must have used all their fuel in tearing themselves free of Earth. Those ships were utterly helpless. Some of them would be shooting off in all directions, every moment getting farther from Mars, and utterly incapable of doing anything about it. Some of them would be pointed at the sun, or close enough to the sun to be captured by it. Some would move on and on past the planets into space... those ships would go on forever if they weren't captured by some star or planet. I didn't swear or curse at anyone. I just doggedly worked out problem after problem, as if I could set everything right by my high school mathematics. On the basis of our own experience I worked out how much fuel the lifeships really needed. Then, since they would have to be so much bigger and stronger, how many lifeships there would have been instead of seven hundred thousand. How many people they could have taken. Allowing a very small safety factor, it came out at ninety-seven thousand. A chance of life for a million people instead of nearly eight million. Not one in three hundred of the people of Earth, but one in twenty-two hundred. I tried to imagine the job I might have had then, the job of picking out ten people from a town of over twenty thousand. As it was, I knew hardly anything about some of the people I'd chosen from a mere three thousand or so. Sammy, Leslie, Betty, and Morgan were all last-minute choices, because someone else had had to come off the list. On the whole I was prepared to gamble on the first two, but Morgan and Betty could be my best choice or my worst for all I knew. What sort of guess could I have made if I'd been confronted with twenty thousand people and told to pick ten? I shook my head wearily. The questions were too big for me. I had juggled too long with figures of life and death — a little life and a lot of death. They weren't anything but figures to me. Perhaps that was why I had done it — to reduce humanity's most frightful disaster to a few real figures, like four and seven and three, with a lot of incomprehensible zeroes after them. I would come again, no doubt. But meantime I had reached a mental dead stop. # _2_ I gave myself a push against the wall, guided myself with my arms, and swam out into the main room of the lifeship, which Sammy had already christened, ironically, "the lounge." Lifeships were simply moving barns. There was nothing to be

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of all, why is reality itself going haywire in the vicinity of Cliff’s office? To learn the answers to these questions, Cliff will have to sacrifice everything — and everybody — that has ever been precious to him. And even then, there’s no guarantee that he’ll like what he discovers. Especially when it points toward the overthrow of the ultimate Creator of the universe itself... First published in samizdat form in 1985, this rollicking, inventive, and blasphemous sci-fi adventure heralded the emergence of Perry Slaughter as a force to be reckoned with in American letters. Nearly three decades later, Deus ex Machina still retains its power to shock, astound, and entertain. by Sinister Regard £1.27 With the computer called ARTHUR, Cliff Peabody has made a major breakthrough in artificial intelligence. It should be the most triumphant event of his professional career — but why, then, is the federal government invading his laboratories? Why is half the country suffering an inexplicable power outage? And, most disturbing of all, why is reality itself going haywire in the vicinity of Cliff’s office? To learn the answers to these questions, Cliff will have to sacrifice everything — and everybody — that has ever been precious to him. And even then, there’s no guarantee that he’ll like what he discovers. Especially when it points toward the overthrow of the ultimate Creator of the universe itself... First published in samizdat form in 1985, this rollicking, inventive, and blasphemous sci-fi adventure heralded the emergence of Perry Slaughter as a force to be reckoned with in American letters. Nearly three decades later, Deus ex Machina still retains its power to shock, astound, and entertain. by Sinister Regard It is January 1, 1913; and Ilaytha is about to begin her service as a test subject to the warlock Edwin Hubble. Despite being a brilliant scientist, Ilaytha is human and thus will never be able to work on her own. Only warlocks like Sergei Diaghilev and Henri Becquerel are allowed to pursue art, science, or literature. Humans exist to perform hard labor and to produce warlock children; but Ilaytha believes herself to be the exception to the rule. Her pride will force her to learn what lies behind the façade the warlocks have created. £0.99 It is January 1, 1913; and Ilaytha is about to begin her service as a test subject to the warlock Edwin Hubble. Despite being a brilliant scientist, Ilaytha is human and thus will never be able to work on her own. Only warlocks like Sergei Diaghilev and Henri Becquerel are allowed to pursue art, science, or literature. Humans exist to perform hard labor and to produce warlock children; but Ilaytha believes herself to be the exception to the rule. Her pride will force her to learn what lies behind the façade the warlocks have created. When psychotherapist Claire Walsch is contracted – against her will – to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that her life is about to be turned upside down. What Claire really wants is to ask some questions, sign some papers and walk away. What she gets is a dangerous adventure with a woman who is uncomfortably unpredictable. An adventure which brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum £5.64 When psychotherapist Claire Walsch is contracted – against her will – to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that her life is about to be turned upside down. What Claire really wants is to ask some questions, sign some papers and walk away. What she gets is a dangerous adventure with a woman who is uncomfortably unpredictable. An adventure which brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum Appleseed - Ex-Machina [Blu-ray]. Import from The Netherlands. Language: English, French Subtitles: English, French, Dutch Producer John Woo's updating of the Japanese anime series. In the year 2133, the Third World War has devastated mankind, and has led to the creation of a utopian society in the hi-tech city of Olympus. Deunen is a female warrior from the scorched wastlelands who meets her long lost boyfriend, Briareos, who has been transformed into a half-machine cyborg. The pair's partnership is tested when Jude Tereus, a 'battle bioroid' joins their ESWAT team. Even more worrying is the fact that Tereus was constructed using Briareos's DNA, causing him to have feelings for Deunen. As Olympus gets ready to hold a global trade summit, the city is hit by a wave of terrorist cyborg attacks. With an increasing number of cyborgs rebelling, Deunen finds herself having to partner Tereus as the terrorist campaign intensifies. £5.98 was £6.98 Price dropped on 9th Jan 2018 Appleseed - Ex-Machina [Blu-ray]. Import from The Netherlands. Language: English, French Subtitles: English, French, Dutch Producer John Woo's updating of the Japanese anime series. In the year 2133, the Third World War has devastated mankind, and has led to the creation of a utopian society in the hi-tech city of Olympus. Deunen is a female warrior from the scorched wastlelands who meets her long lost boyfriend, Briareos, who has been transformed into a half-machine cyborg. The pair's partnership is tested when Jude Tereus, a 'battle bioroid' joins their ESWAT team. Even more worrying is the fact that Tereus was constructed using Briareos's DNA, causing him to have feelings for Deunen. As Olympus gets ready to hold a global trade summit, the city is hit by a wave of terrorist cyborg attacks. With an increasing number of cyborgs rebelling, Deunen finds herself having to partner Tereus as the terrorist campaign intensifies. When psychotherapist Claire Walsch is contracted - against her will - to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that she is about to experience something far beyond her belief. The physical, mental and psychological journey that follows brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. ..".I couldn't put this book down. It was fast paced, action packed with strong female characters. Awesome read!" "Talk about keeping you on the edge of your seat! This was really good right from the get go... Get this book I highly recommend it and I hope there is a sequel coming in the future." "adjective: excellent 1. extremely good; outstanding..." Reader Reviews, Amazon.com "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum by Createspace £8.99 When psychotherapist Claire Walsch is contracted - against her will - to take on the case of the infamous schizophrenic Marine Force Recon Captain Leah Ryan, she has no idea that she is about to experience something far beyond her belief. The physical, mental and psychological journey that follows brings the realization that reality may not always be as black and white as we make it out to be, and that the truth can be far more sinister and complicated than we give it credit for. ..".I couldn't put this book down. It was fast paced, action packed with strong female characters. Awesome read!" "Talk about keeping you on the edge of your seat! This was really good right from the get go... Get this book I highly recommend it and I hope there is a sequel coming in the future." "adjective: excellent 1. extremely good; outstanding..." Reader Reviews, Amazon.com "This is a page-turner, a 'can't put down' kind of read..." "Stunning piece of writing. Riveting action..." "Riveting and engaging... Tightly written and well-paced..." Reader reviews, The Athenaeum by CreatespaceFunny Jokes, Quotes, Videos & More Privacy Policy Yuckitup.com respects your privacy. Any personal information you provide to us including and similar to your name, address, telephone number and e-mail address will not be released, sold, or rented to any entities or individuals outside of Yuckitup.com.

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PM COPY THAT! 10-4, we're outa here............ WAIT! I just read this article: http://www2.ljworld.com/news/2012/feb/25/us-taliban-talks-worry-afghan-women/ meh... now, I dunno.:concern:.......should we give it up? Yes, unless of course we plan on spending the next century there. We have enough problems, we don't need theirs. Teetop 02-25-2012, 03:51 PM I wish someone would've wiped their ass with the pages just to see the frenzy that would've ensued. :biggrin: You asked, here it is. (http://moonbattery.com/?p=8533) Odysseus 02-25-2012, 04:21 PM You asked, here it is. (http://moonbattery.com/?p=8533) http://www.youtube.com/watch?v=69VIER7nzz8&feature=player_embedded#! A few other highlights of the hypocrisy of the Muslims on this subject: From the description of the Wahhabi takeover of the town of Taif, in Saudi Arabia: The Wahabbis tore up the copies of the Qur’an al-karim and books of Tafsir, Hadith and other Islamic books they took from libraries, Musjids and houses and threw them down on the ground. They made sandals from the gold-gilded leather covers of the Qur’an copies and other books and wore them on their filthy feet. There were ayats and other sacred writings on those leather covers. Leaves of those valuable books thrown around were so much that there was no space to step in the streets of Taif. Although Ibn Shakban had ordered the looters not to tear up the copies of the Qur’an al-karim, the Wahabite bandits , who were gathered from the deserts for looting and who did not know the Qur’an al-karim, tore up all the copies they found and stamped on them. Only three copies of the Qur’an al-karim and one copy of the Sahih of al-Bukhari were saved form plunder in the big town of Taif. Malawi Muslims burn Gideons Bibles in protest October 5, 2010 @ 6:25 pm By Reuters Staff http://blogs.reuters.com/faithworld/files/2010/10/bible-350x252-custom.JPGMuslims in southern Malawi have been burning Bibles in protest against their distribution in Islamic schools byGideons International (http://www.gideons.org/Splash.aspx) [1], a senior Muslim Association of Malawi official said on Tuesday. Sheikh Imran Sharif, the association’s secretary general, said the burning of Bibles was carried out by a few Muslim fanatics and the association has ordered them to stop. The Muslim protest has been widely criticised in secular Malawi, which has had little religious friction. (Photo: Bible, 14 Dec 2008/Edgeurged)Malawi has 1.7 million Muslims, mostly living in the south of the country, that has a population of about 15 million. Gideons International, which is dedicated to providing copies of the Bible to people around the globe, said on its website it has distributed about 90 million Bibles in 22 countries in eastern Africa. http://www.youtube.com/watch?v=4pPz4xfcvu8 Military burns unsolicited Bibles sent to Afghanistan Story Highlights Unsolicited Bibles sent by U.S. church were confiscated about a year ago The Bibles were printed in two most common Afghan languages Military feared they could be used for proselytizing, which is forbidden to troops Military didn't want to risk any distribution of the Bibles and angering Muslims d/div>v!--startclickprintexclude-->(CNN) -- Military personnel threw away, and ultimately burned, confiscated Bibles that were printed in the two most common Afghan languages amid concern they would be used to try to convert Afghans, a Defense Department spokesman said Tuesday. The unsolicited Bibles sent by a church in the United States were confiscated about a year ago at Bagram Air Base in Afghanistan because military rules forbid troops of any religion from proselytizing while deployed there, Lt. Col. Mark Wright said. Such religious outreach can endanger American troops and civilians in the devoutly Muslim nation, Wright said. "The decision was made that it was a 'force protection' measure to throw them away, because, if they did get out, it could be perceived by Afghans that the U.S. government or the U.S. military was trying to convert Muslims," Wright told CNN on Tuesday. Troops at posts in war zones are required to burn their trash, Wright said. The Bibles were written in the languages Pashto and Dari. This decision came to light recently, after the Al Jazeera English network aired video of a group prayer service and chapel sermon that a reporter said suggested U.S. troops were being encouraged to spread Christianity. The military denied that earlier this month, saying much in the video was taken out of context. "This was irresponsible and dangerous journalism sensationalizing year-old footage of a religious service for U.S. soldiers on a U.S. base and inferring that troops are evangelizing to Afghans," Col. Gregory Julian said. The military says a soldier at Bagram received the Bibles and didn't realize he wasn't allowed to hand them out. In the Al Jazeera video, which shows the Bibles at the prayer service, an unnamed soldier says members of his church raised money for them. The chaplain later corrected the soldier and confiscated the Bibles, Wright said. RedGrouse 02-25-2012, 07:55 PM Assuming this even happened. All it takes is one local insurgent to start the RUMOR that a Koran is being burned to whip the uneducated masses into a frenzy over there. Like in Uruzgan Province last year when the Taliban tried to claim we bayonetted a Koran. That got the locals riled up until we pointed out to the provincial elders the 30 year old soviet bayonet stuck in the Koran wasn't used by either Australian or American forces. This is the Taliban propaganda wing yanking ISAFs chain and getting a 4 Star General to jump for them. And yes I know they reportedly found pieces of a Koran. We found pre burnt Korans in raids last year. Paranoia runs deep in them and I mean really deep. Kay 02-26-2012, 12:42 AM I can't even read on this subject without needing an extra blood pressure pill. Where were all the riots over the Taliban blowing up the hillside Buddhas? Oh yeah, Buddists, Christians and other Godly religions don't do this sort of thing. Only pure evil cults do. We won the wars both in Iraq and the shithole of Afghan, but we lost the wars for the hearts and minds. We've done all the good we are ever going to do there. We have given them an infrastructure, trained their police and military and shown them what a better way of life can be like. Now it's up to them. They can sink or swim. We need to just get all our people out of there I say. Kay 02-26-2012, 01:05 AM But my 1st preference would have been this: The third option is the punitive expedition. Simply put, we could have hit the Afghans hard, destroyed as much of the country as possible in as short a time as possible, and warned them that if they messed with us again, we'd be back in force to finish the job. We'd have left the countryside in ruins and created a humanitarian disaster, but we'd also have let the world know that were were not to be trifled with. The example of this paradigm occurs throughout history, from the Greek's destruction of Troy, Alexander's destruction of Thebes, Rome's destruction of Carthage, Jerusalem and the various tribal strongholds of northern Europe, and various other atrocities. Of course, the survivors would hate us, but they would also fear us, and, as Machiavelli famously wrote, it is better to be feared than loved. Also, given the nature of our enemies, they'd have understood and expected this response, as it is what they would have done if the roles were reversed. The rest of the world would have screamed bloody murder, but let's face it, they were going to do that no matter what we did. Starbuck 02-26-2012, 12:24 PM Obama made a serious mistake in apologizing for the burning of the Koran. He should have stood his ground defiantly or, lacking that spine, should have said nothing. Now we are told that he has sent Hamid Karzai a letter of apology and thanked Karzai for his efforts at restoring order. In return, Karzai has issued a statement as follows: Earlier on Sunday, in a televised

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cause” of ISIS except only in the sense that the “failure” to exact regime change in Syria has prompted the West to continue propping up ISIS and other terrorist groups until the government in Damascus falls – and only when Damascus’ regional and global allies abandon it. The West Got What it Wanted in Libya – And Created ISIS in the Process The West’s claims during the Vienna talks that if only they get their way in Syria, the threat of ISIS will subside, is betrayed by the events surrounding the very rise of ISIS in Syria in the first place. Just before the conflict reached critical mass in Syria during 2011, the US, UK, France, other NATO members, as well as Saudi Arabia, Qatar, and the United Arab Emirates (UAE), were already in the process of fully dividing and destroying Libya in pursuit of regime change. They insisted that regime change was the only way to end the bitter fighting that had swept the country – regime change that just so happened to fulfill the long-held desire by Washington and Europe to see Libyan leader Muammar Qaddafi ousted from power. Through arming what the West called “rebels,” and through direct military intervention which included large-scale, nationwide airstrikes, naval bombardments, and even special forces, NATO devastated the country and turned it over literally to Al Qaeda. The West’s “rebels” turned out to be sectarian extremists all along, and in fact – with NATO’s help – they promptly took their weapons, fighters, and cash to begin the invasion of northern Syria via Turkey later that year. The Business Insider would report in its article, “REPORT: The US Is Openly Sending Heavy Weapons From Libya To Syrian Rebels,” that: The administration has said that the previously hidden CIA operation in Benghazi involved finding, repurchasing and destroying heavy weaponry looted from Libyan government arsenals, but in October we reported evidence indicating that U.S. agents — particularly murdered ambassador Chris Stevens — were at least aware of heavy weapons moving from Libya to jihadist Syrian rebels. There have been several possible SA-7 spottings in Syria dating as far back as early summer 2012, and there are indications that at least some of Gaddafi’s 20,000 portable heat-seeking missiles were shipped before now. On Sept. 6 a Libyan ship carrying 400 tons of weapons for Syrian rebels docked in southern Turkey. The ship’s captain was “a Libyan from Benghazi” who worked for the new Libyan government. The man who organized that shipment, Tripoli Military Council head Abdelhakim Belhadj, worked directly with Stevens during the Libyan revolution. Belhadj, it should be mentioned, was the commander of US State Department-listed foreign terrorist organization, the Libyan Islamic Fighting Group (LIFG) – which is literally Al Qaeda in Libya – and was so before, during, and after the 2011 Libyan war. Belhadj was also reportedly aligned with ISIS as it officially established itself in the shattered North African state. Fox News would report in its article, “Herridge: ISIS Has Turned Libya Into New Support Base, Safe Haven,” that: [Catherine] Herridge reported that one of the alleged leaders of ISIS in North Africa is Libyan Abdelhakim Belhadj, who was seen by the U.S. as a willing partner in the overthrow of Libyan dictator Muammar Gaddafi in 2011. “Now, it’s alleged he is firmly aligned with ISIS and supports the training camps in eastern Libya,” Herridge said. It is clear that despite Western claims that regime change in Libya would be the beginning of the end for Libya’s violence and instability, it was only the end of the beginning – and not only for chaos in Libya – but for other nations across North Africa and in Syria itself. Using Another 9/11 to Justify Creating Another Libya NATO’s intervention and regime change in Libya did not avert a refugee crisis, it helped create one. NATO’s intervention and successful regime change in Libya did not make the region or the world safer, it turned the entire nation into a breeding ground for terrorist organizations with so-far unprecedented reach and operational capacity. NATO’s goals in Libya did not prevent the refugee crisis, it helped start it. And with all of this in mind, having seen this and taken full stock of Libya’s outcome, the West has nonetheless moved forward with precisely the same agenda in Syria. In all reality, the West has no intention of bringing peace or stability to Syria. Their goal is to leave Syria as divided and destroyed as Libya, and to use the chaos and instability fostered there as a springboard for other targets of the West’s proxy warfare – most likely Iran, Russia, and targets deeper in Central Asia. The West promises that it will end the chaos in Syria, just like they promised it would end in Libya. It will not end in either. With Libya’s fate in mind, and a repeat performance clearly taking shape in Syria should the West get its way, it must be made clear that no matter how many innocent people are killed by terrorists the West itself helped create and perpetuate, they will not get an opportunity to turn Syria into the “Libya of the Levant,” no matter how convenient and well-timed these killings are, no matter how deep they are within the heart of Europe or North America, and no matter how tragic and regrettable the aftermath is. Tony Cartalucci, Bangkok-based geopolitical researcher and writer, especially for the online magazine“New Eastern Outlook”.In this instructable you will learn how to make a Q&D-Poor man's-Skinner-Sadist-Jeopardy game . First off, the disclaimer: I'm not responsible of whatever you do. You have to know that with a great power comes...bla-bla-bla. Just be careful and remember that electricity reserves respect. While the energy involved in this project is generally safe, it can be fatal (or at least very harmful) given certain ... While being a bit lengthy and requiring experience with Arduino, this contraption is bound to grant you infinite glory among your friends, toddlers and grownups alike! Step 1: What You Need Here's a list of the materials and parts I used: The Frame * 5 x 4-feet long rectangular profile (0.5" x 0.5") pieces of wood, as solid as possible. Although you could probably get away with plywood if you wanted to, I a ... Update! See Step 32 to find out how to use this project with a green laser! Also - checkout the LaserTweet Instructable to make this project display data from Twitter: http://www.instructables.com/id/LaserTweet-Twitter-Projecting-Laser-Show/ This project uses an Arduino and some cheap audio speakers to create a real laser show with full X and Y axis control. The included source code lets you easily draw tex ... For the Smart Cities exhibition in Leeds in a couple of weeks, we’ve been building a physical representation of an agent based simulation. Hex Bug Spiders are relatively cheap hexapod robots that are controlled via an infra-red transmitter which has an A or B code so that you can control two simultaneously. The way it walks is referred to as the Jamius walking mechanism after its inventor (see: http://www.y ... Idea: To take one of my old Playstation 1 controllers and extract the dual thumbstick setup so that it can be easily used in a microcontroller project (in my case: with the Arduino) without extra libraries or drivers that you would need if you want to use the entire controller. Please let me know what you think or if you have questions/criticism for me! I'm always looking to learn new things.Required materi ... Make A "doorbell" using an Arduino Uno, a Wave shield from Adafruit, a small speaker, a plug, a Sharp distance sensor and a Shaun the Sheep. Our Shaun is used in an open doorway to alert store staff when a customer has entered. Step 1: Parts List 1. Wav Shield Party Pack (includes speaker and SD card) - $35 2. Arduino Uno - $30 3. Power plug - $7 4. Sharp Distance Sensor - $14.95 5. Shaun the Sheep found o ... I bought this skull to decorate my computer desk. However, analyzing better, I could do something more interesting. I hope you enjoy. Step 1: Materials - A plastic skull - 8 screws; - Microcontroller (I used an Arduino board); - A Protoboard - A nunchuck (for nintendo wii control) with a adaptador Note: I bought the adapter but can be easily made by following this step by step: http://www.instructables.com/ ... Welcome to my 3rd Instructable everyone ! Today we're going to build a 'device' to control a mini-sized helicopter with a Wii Nunchuk. The helicopter that we're using is a cheap (26$) 3-channel (yaw, throttle, pitch) helicopter that I bought a 1 month back from Dealextreme.com . I can say that it is a VERY durable heli : I have crashed more thant 100 times and it's still working ! It is not radio-controlled ... I just hope every body's heard. The Bird is the Word! This is a simple device to play Surfin Bird really loudly when someone trips off the motion sensor. If you don

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zitane (TAIW) with nitrosonium tetrafluoroborate in sulfolane to form 4,10-dinitroso-2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazaisowurtzitane (TAIW(NO)2). The 4,10-dinitroso-2,6,8,12-tetraacetyl-2,4,6,8,-10,12-hexaazaisowurtzitane (TAIW(NO)2) in turn was treated with nitronium tetrafluoroborate in sulfolane to give the explosive, 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (HNIW). These flouroborate reagents are very expensive and, additionally, disposal of left-over waste is very costly because of the presence of fluoride.Tag: soft squidgy goodness When was the last time you recommended a book by saying any of the following? . “Boy, the grammar was spot on – what a read!” “Most of the dialogue was just like real life.” “There were literally no plot holes – I totally believe that situation, or something very similar and just as cohesive, …Canadian Crypto Businesses Now Regulated as Money Service Businesses (MSBs) Canada Crackdown – The Canadian government just announced that going forward it will regulate any businesses “dealing in virtual currency” as Money Services Businesses (MSBs). This move is aimed at protecting Canada’s financial ecosystem from potential terrorist financing activities and money laundering. Canada considers money service businesses as those that handle money, but are not ‘official’ chartered banks; such as money transfer services and foreign exchange services. The report states: “Persons and entities that are “dealing in virtual currency” would be financial entities or other entities deemed domestic or foreign MSBs, as the case may be. As required of all MSBs, persons, and entities dealing in virtual currencies would need to implement a full compliance program and register with FINTRAC.” Under FINTRAC (Financial Transactions and Reports Analysis Centre of Canada), these companies are required to have a complete Know Your Client (KYC) and Anti-Money Laundering (AML) policies, procedures, and reporting. These businesses are also required to report any suspicious activity on their platform, immediately. The Canadian government believes that these new amendments prevent money laundering and terrorist activities, while not holding back potential innovation. If these new amendments are fully accepted, they will come into effect exactly 12 months after their registration – no need to panic. >> Operation Crypto Sweep Crypto Regulation Front-Runner According to IMF analysis, Canada is known as one of the most financially stable nations in the world. The country avoided major bank shutdown during the Great Recession of 2008, in the U.S. Much of this stability was from tight regulations and strict reporting for MSBs and chartered banks. Just recently, a number of Canadian banks followed suit of the U.S. Banks and banned their customers from buying cryptocurrency via their banks’ credit cards. The Bank of Montreal (BMO) even went as far as banning crypto purchases via Interac E-Transfer. Last Month, Canadian Government also took part in “Operation Crypto Sweep” in which the North American Securities Administrators Association (NASAA) sent 70 cease-and-desists letters to operations running in the U.S. and Canada that they believe were running scam cryptocurrency companies. Later it was found that all ICOs operating within Canada were found ‘fraudulent.’Trechus subnotatus Trechus subnotatus is a species of ground beetle in the Trechinae subfamily. Description Beetle in length from . References Category:Beetles described in 1831 subnotatusMonthly Archives: March 2015 Guess what, people. You get to practice your religion up to the point where you infringe on someone else’s life. That’s it. That’s the cut off. That is as far as you can push your religion. (In fact, that is as far as you can push anything you want to do.) That’s all “religious liberty” means. Because if you can force your religion onto someone else, then they don’t get to take part in this “Freeedom of Religion” the Framers thought so important that they put it into the very First Amendment. Guess what else, people. “Religious liberty” is not under assault. Not in any way shape or form. What is “under assault” — a horribly inaccurate term if there ever was one — is the privilege Christians have had until recently to force their religion on other people. It really is as simple as that, and I dare someone to prove otherwise. I am not an economist. I was a software engineer who decided to become a stay-at-home dad/Household Manager. I had no course on Econ while in college. I had a high school understanding of supply and demand. A few months ago, I picked up “An Idiot’s Guide to Economics”. So, Men’s Rights Advocates are mostly horrible people with a highly mistaken view of reality. I admit, however, that there are a couple-few places where work could be done in the area of helping men. The courts when dealing with fathers, while getting better, could probably be even more egalitarian. Men could use their own shelters when they are the victims of DV. The rate of incarceration of men, especially men of color, may be far higher than they should be in relation to women. (Yes, I used some weasel words — I’m trying to be charitable to a generally terrible group of people.) Perhaps there should be an organization that works towards fixing these inequities. So, men who are feeling lost, unsure, threatened and violated, complaining on the internet should help you out just fine. It’s not like a Google search for “Men’s Shelter” might give you someplace to go if you are in trouble, and maybe a place to donate time or money to help out Men. I didn’t link because Google is good at knowing where you are and my search is not your search. I’m sure that Google really has no response for any other men’s issues, too. I really have no other response than what David at We Hunted the Mammoth has already said — A Voice For Men has set itself up as the premier site for Men’s Issues and they have no plans to do anything for men. As the title says, this has been a tough winter. Not really in the snow department until lately, but in the cold department. Again. Last year’s temps were no better. The only problem with snow, until a few days ago, was that it wouldn’t leave because we stayed below freezing for a long time. That big storm hit the other day and now we have a lot of snow left because of the cold. I am not going to get to go to the Philadelphia Flower Show this year — first one I’m going to miss in 4 years. I had forgotten it was happening already, and then we had a sick son and then ice one morning and snow another. It was not conducive to getting out of the house this week, not even to the supermarket. Spring cannot get here fast enough. Played a lot of the video game Destiny the past couple of months. I like it a lot, though I am now at a point where I’m not getting any better. The story line you play through makes very little sense. Still, I like it. Got a new laptop several weeks ago and finally got Daz Studio and all my content moved over. I can get back to putting together some renders, and maybe some of them will actually be good. I hope to get my camera out for some pictures, too. And I keep meaning to get back to practicing guitar. So I hope my artistic side can be exercised over the next few months.Hopefully I’ll be back before a whole month passes.It is with a heavy heart that I mourn the loss of Lebbeus Woods. He was a tremendous inspiration to me in my pursuit of architecture, and I was incredibly fortunate to work closely with him over the past year. Our long conversations at his table will forever illuminate my mind. His visionary work will continue to influence the discourse for countless years to come. I dedicate the exhibition Field Conditions to him and his enduring legacy. – Joseph Becker Can there be architecture without buildings? What if a wall or a floor went on forever? The works in our current show, Field Conditions, pose these questions and more about the construction, experience, and representation of space. In an attempt to expand our general interpretation of architectural ideas, its focus is on an array of projects by both artists and architects that redefine the relationships between invisible and visible, figure and ground, finite and infinite. As an exhibition, Field Conditions feels like the tip of the iceberg to me, a leaping-off point for further investigation and analysis on these intersections between art and architecture practice and the abstract concept of “space” as a subject. The SFMOMA presentation, with 13 projects by 11 artists and architects, is of course limited by the physical factors of the gallery and as such cannot begin to be a complete and comprehensive analysis of the topic and theory that interests me here. Of course, neither can a singular essay devoted to

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ations and used them to debunk the whole notion of a yeti. Annoyed but undeterred, Slick turned his attentions to another reported man-ape creature, this one said to be living deep in the woods of the Pacific Northwest: Sasquatch, often referred to as Bigfoot. That we know anything at all about Tom Slick's search for the yeti and Bigfoot is due almost entirely to Coleman's efforts. A cryptozoologist himself, Coleman spent the better part of thirty years researching Tom Slick's life, particularly as it related to his contributions to cryptozoology. The result was his 1989 book _Tom Slick and the Search for the Yeti_. Coleman wrote in the introduction to his book: "This man would throw his fortune behind a serious search for the mysterious creatures. Who was this man? He was a handsome, lean, prematurely white-haired man, soft spoken, with a slight Southern drawl. Tom Slick was his name, more fictional-sounding than real. And in many ways, Tom Slick's life was the stuff legends are made of...Tom Slick was given many names during his short, event-filled life. But today, hardly anyone remembers him. And that's a shame." Like his father, Slick died when he was forty-six. A plane he was riding in exploded over Montana in 1962. Had he lived, Tom Slick might have hooked up with or even founded the Texas Bigfoot Research Conservancy, which carries on Slick's interests in Texas. The Texas Bigfoot is believed to be a southern cousin of the Pacific Northwest's Sasquatch. Of the one hundred or so sightings reported on the center's website, the center deems about seventy-five of those sightings as legitimate in the way that sightings of unidentified flying objects are legitimate; both remain unidentified. Persistent reports of a Sasquatch-like creature living along the Sulphur River, just across the state line in Arkansas, inspired the movie _Legend of Boggy Creek._ The modern-day Texas Bigfoots (Bigfeet?) go by many names, some of which sound like high-end fishing lures: Night Screamer, Hawley Him, Haskell Rascal, Wooly Bugger and Caddo Critter. The people at the Texas Bigfoot Research Conservancy believe that the sightings indicate a primate, albeit an elusive one for which no remains have ever been positively identified. Recent sightings have occurred in the Sam Houston National Forest, near the San Jacinto River. We might say that all of this started with Tom Slick, but to call him Texas's first cryptozoologist we would have to dismiss the Comanches, Tonkawas and other Texas tribes who believed strongly in a man-ape creature in the same way that they believed in, say, bears. The Hill Country has had a few sightings, too. One came in 1902 in a cedar chopper community called Panther Path in Travis County. A group of young people were fishing and hunting in the area above the old McDonald Dam when a hairy, eight-foot-tall man confronted the young sportsmen with a large club, the better to pulverize them. Bigfoot let loose a bloodcurdling scream and advanced in what can only be described as a menacing manner toward the terrified young people. They ran for the wagons and barely made it. Bigfoot followed them for a while before giving up and disappearing into legend and lore. Bigfoot was the target of many a Hill Country hunter for a while after that, but neither hide nor hair was seen of the creature again. If only Tom Sick and his team had been there! But I may be doing Tom Slick an injustice to focus solely on his searches for abominable snowmen, Bigfoot and several other perhaps mythical creatures. This was a man who founded what is today the Southwest Foundation for Biomedical Research, the Institute of Inventive Research, the Southwest Research Institute and the Mind Science Foundation. Much of the work he founded continues today. Slick helped develop Brangus cattle and at one time had one of the three largest herds of Angus cattle in the country. Following in the footsteps of his wildcatter father, he discovered the Benedum Field in west Texas, one of the largest oil strikes in the United States after World War II. Most of us don't have any reasonable expectation of having Tom Slick's resources or of leaving such a legacy. What most of us have in common with Tom Slick is that we, too, want to know, once and for all, if there is or ever was such a creature as the yeti or Bigfoot. Like Tom Slick, we just want to know. ### THE PLIGHT OF THE PLEUROCOELEUS We don't usually think of dinosaurs when we think of Texas. We might think about the state's officially designated large mammal, the longhorn, or the state small mammal, the armadillo. We know that the state bird is the mockingbird, the state tree is the pecan and the horned lizard (or horny toad, as most of us call it) is the state reptile. Rock hounds might even know that the state stone is petrified palm wood. Seldom is heard a word, discouraging or otherwise, about the state dinosaur, the pleurocoeleus. The pleurocoeleus is the official state dinosaur of Texas. Whether Texas actually needs a state dinosaur is open to debate, but the pleurocoeleus ( _Brachiosaur sauropod_ ) was so designated by the state legislature 1997. It's our dinosaur, by golly, and we're Texans, so we're going to be proud of it, even if it wasn't what you might call ferocious. You might think that Texas would have adopted a carnivore, but our dinosaur was a strict vegetarian. At least it was big—about fifty feet long and weighing in at about twenty tons. Paleontologists tell us that despite its size, our dinosaur was decidedly mild-mannered. Fight or flight? The pleurocoeleus probably didn't have to give the matter a lot of thought. We can watch and listen to mockingbirds, pick pecans and we know a longhorn cow when we see one and an armadillo, which we can't always avoid when they try to cross the road. The pleurocoeleus hasn't been seen in these parts for, oh, about sixty-five million years, give or take a few million years either way. But we have proof that they lived here. Near Glen Rose, at the appropriately named Dinosaur Valley State Park, on the banks of the Paluxy River and in the riverbed itself, are some remarkably well-preserved pleurocoeleus tracks. These are some of the best dinosaur tracks in the world, which is why paleontologists love the park and have ever since Roland T. Bird of the American Museum of Natural History visited the site in 1938. Bird realized that a set of double tracks showed an herbivorous sauropod—most likely our boy, the pleurocoeleus—being chased by a meat-eating carnosaur. This was the first time sauropod tracks had been discovered anywhere in the world, which caused no small amount of excitement back in New York. The Glen Rose tracks were duly sent to New York and displayed at the American Museum of Natural History. The pleurocoeleus obviously couldn't get away from the site fast enough on that particular day, but since then its tracks have been scattered hither and yon, to the Texas Memorial Museum in Austin and, unfortunately, into the private residences of many amateurs—or vandals, depending on how you look at these things. The dinosaur tracks are a major wonder, but it's a small wonder that any tracks are left here at all. People complain that all the "good" tracks have been removed from the Paluxy River Valley. A woman in Glen Rose told me that a lot of area families have a quarried dinosaur track or two in their homes. "You usually see them on people's living room wall," she said. It took a special set of circumstances to preserve the tracks for all these millions of years. Scientists believe that a violent storm blew across the shoreline a few days before the tracks were made and created a series of sand- and lime-laden mudflats. A herd of pleurocoeleus came ambling across the sticky and still-wet mud in search of a primordial salad, followed in interested pursuit by the carnosaurs looking for some fresh sauropods; the pleurocoeleus qualified. True to their pacifistic nature, the pleurocoeleus tried to run away, but we don't know if they won that particular footrace or not. No intact skeleton remains were ever found, just huge saucerlike depressions from their hind feet and smaller tracks, much like horseshoes, from their front legs. The primal, existential struggle for food and survival was preserved in stone when the seashore turned to stone, leaving behind the rocks we see in the park today, including the ones with the dinosaur prints. We in Texas have never collected dinosaur fossils like we have collected, say, arrowheads, but the state has had its fair share of fossilized dinosaur discoveries over the years due to a quirk of ancient geography dating back to when much of what is now Texas was covered by an ancient sea. As the sea level rose, the land was covered with

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researcher/consultant/trainer/presenter, not a practitioner – getting practitioners to speak in their own language works really well). It leverages and demonstrates the social and collaborative qualities of the Second Life platform. There were some hitches on the day (aren’t there always with presentations in Second Life?!), and Jo was called away to attend to something else so couldn’t be in-world to assist as she normally would have, but overall I felt that this presentation worked a lot better than the Go Virtual 07! one. As for images there are only a few, with Konrad Glogowski taking a few screenshots, and Alan Levine taking this one and this one. These pictures only show the section of the presentation held on Jo’s personal island – illustrating the need to organise thorough documentation of an in-world event to give a more accurate impression of what happened. Both Jo and I will continue to explore the ideas discussed in the post. (That’s her in the picture above supporting my Go Virtual 07! presentation – thanks again Jo!) I enjoy using Second Life as a presentation platform, and I will be taking the many lessons learned during my experiments and continue to develop my presentation style. Visit the presentation in the sky Finally, the ‘Virtual Worlds – Trends and Opportunities’ presentation for Go Virtual 07! on the sky platform will be there for a while (until we need the prims for something else!), so if you get a chance, check it out. We put a heck of a lot of work into it, and it’s a bit of a shame that not many people have seen it yet – an issue this blog post, in part, is intended to hopefully rectify. To find the presentation you need to go to jokaydia’s landing point, look for the Teleporter sign and select Sean FitzGerald’s Virtual Worlds Presentation. Jo and I are pleased with how well it went, especially since it was our first event. There were a few of the usual technical glitches that we come to expect in Second Life, and we learned a few lessons for next time, but overall we think it was a great success. We actually maxed-out the sim at 40 avs and had several people trying to get in throughout the event! One thing I think worked well was mixing up the media. We alternated slide presentations with videos, and one presenter used an oversized Thinc book. It made for a very multi-media event. We had intended to use streaming audio, but as we were about to set-up we found someone else had pirated our rented Shoutcast server! It wasn’t such a bad thing though – only a few presenters wanted to use voice and it would have added another variable to an already challenging session. Thanks to all those who presented and provided videos. And a special thanks to Corwin Carillon for dealing with a flood of newbies’ questions in IM… asking them to send him their questions worked a bit too successfully it seems! Overall, the presentation seemed to go quite well, although it’s always hard to tell with presentations in Elluminate. I didn’t pay any attention to the chat channel… I focused on the presentation while Jo did a great job of fielding questions in chat. I always encourage chat – I like having a back channel going on. I like it that people are having rich conversations provoked by the topic that I am presenting. It’s great to see people sharing resources and helping each other out too. I fluffed my punchline a bit. I wanted to finish up by making a point about the need for educators to pay attention to virtual worlds, or they will no longer be relevant in the eyes of Net Gen students who are growing up completely accustomed to avatarised environments. I took the risk of using a famous clip from the South Park episode where the boys are represented playing World of Warcraft to illustrate this point. The language in it is very ‘blue’, which is typical of South Park, but the clip is funny, and I think it does a great job of illustrating the danger of teachers (and other adults) coming to be seen by the Net Gens as “artards” (r-tards… gamer speak for retards) for completely misunderstanding what young people are doing online, and the value of online interaction for them. My intention had been to shock, but not offend. I wasn’t sure whether I was going to use the clip right up until the end, but the audience seemed pretty receptive up until that point, so I decided to let it rip. Unfortunately, between being tired and nervous, and feeling rushed as we were running out of time, I didn’t get a chance to actually say: “The last reason I think educators need to pay attention to virtual worlds is so that our students don’t think we’re artards.” In the rush I also didn’t give a blue language warning, which I regret, and to make matters worse the the clip kept looping! Several people seemed offended, which is understandable, but I think most people got the point. Anyway… if you get chance check out the presentation resources – there is a lot there to explore about what’s happening in the virtual world space. There is currently an explosion in the number and population of online 3D virtual worlds. This development could even be heralding the next evolutionary phase of the Internet – the 3D web. This session will provide an overview of the latest developments in online 3D virtual worlds and describe some of their unique characteristics. We will also look at how these environments can be used in education and how they can help explore new learning models. We will look at why it is important for educators to pay attention to online 3D virtual worlds and become involved in their development. The session will focus on Second Life, one of the more popular and flexible online 3D virtual worlds. Outcomes At the end of the session participants will have an understanding of the following questions: What are online 3D virtual worlds? How popular are they becoming? What are some of the characteristics of online 3D virtual worlds and what new opportunities do they present for online education? What are some of the ways online 3D virtual worlds can be used in education? What are some of the challenges educators face when using online 3D virtual worlds? Why do educators need to pay attention to online 3D virtual worlds? What does the future hold for online 3D virtual worlds and the 3D web? Jo Kay (aka jokay Wollongong) and Sean FitzGerald (aka Sean McDunnough) will host an event within the 3D online virtual world of Second Life, showcasing some of the Australasian educational projects currently being undertaken using the Second Life platform. A number of educators from Australia and New Zealand will give brief overviews of their educational activities within Second Life. After the presentations there will be an opportunity to explore some of the educational spaces and projects featured. Participants will be provided with landmarks and in-world resources to assist them to further explore the educational uses of Second Life in the future. Outcomes At the end of the session participants will have an understanding of: A number of projects currently being undertaken in Second Life Some possible educational uses of Second Life How Second Life can be used for online presentations and web conferencing Share this: Like this: Sean FitzGerald I am an independent researcher, consultant, trainer and presenter with an interest in emerging technologies - particularly social media and virtual worlds - and their impact on society. I'm interested in exploring how we can use these technologies to transform individual and collective consciousness so that we can better deal with the serious challenges facing humanity and help create a just and sustainable world.Culture Blog While so much in British politics is on hold to avoid leaving Europe, the government are proceeding with plans to make all bodies the possession of the State. In a short time, we will be presumed to be organ donors unless we take the trouble to opt-out: This has been the law in Wales for the last 3 years, so that those of us visiting Wales for the day have been in an ambiguous position: if there was a terrible road accident, would they check whether we were resident in Wales before taking our organs or after? The opt-out is available (https://www.organdonation.nhs.uk/register-to-donate/refuse-to-donate/refuse-donation-form/) but it is not fool proof. Before my brother had his tumour removed ten years ago, the consultant surgeon reassured my parents that he would under no circumstances remove his leg on the operating table; but before going under the anaesthetic, alone, my brother had to sign a disclaimer allowing the surgeon to do just that if he deemed it to be necessary. The tumour would not have been removed if he had not signed to allow them to take his leg as well. There is nothing to stop people being put over a barrel in the future, that if we do not agree to have our organs harvested at death then we will not be treated in life. The BBC is not just complicit in this matter but aggressively so. Their propaganda is that those who donate organs save lives, they are saviours. We are told that by our death we can save other people and that such a selfless act will ease the mourning of our relatives, as though the dead continue to live, resurrected in someone else’s body.

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serious expression turned decidedly less so. "If I'm not mistaken, Roland, I believe you just said I was . . . over the hill." Reacting to the spark of playfulness in her features, he laughed. "If you're over the hill, Lizzie, then I've already got one foot in the grave." He looked down at his legs. "Oh wait . . ." He laughed. But she only smiled and eyed him. "I'm so very grateful you lived." Her eyes lit with a sparkle that precious stones would envy. "And that you got to keep your leg." "And that, my dear Lizzie—" On impulse, Roland reached out his hand, much as he might have done if he were attempting to stroke a skittish doe. And to his surprise, she met him halfway. "That is completely due to you keeping your promise. For which I will forever be grateful." He gently tightened his hand around hers, and the light in her eyes deepened. But too quickly for him, she pulled her hand away. And he reminded himself again, _Friendship. Only friendship._ She reached into her pocket and pulled something out. A thin bundle of letters, he saw upon closer inspection, tied with string. "I'd like to show you something," she said. "And get your opinion, if I could." "Letters from a secret admirer?" he asked, forcing humor into his voice. "No," she whispered, not looking up. "These belonged to a soldier who was here at Carnton. A boy. He was no more than thirteen or fourteen years old." She handed them to him. Sobered, he turned the thin bundle in his hand. "There's no address." "I know. So I have no idea where to send them. Or if Thaddeus wrote them. Or if they were written to him." "Thaddeus?" "I found the name written on a page torn from a Bible. It was with the envelopes in his pocket. But there was no last name. I asked Colonel McGavock this morning if he would check with the War Department to see if they could look up his first name to learn his last. He said he would contact them for me. But look at the string, Roland. It's tied in a knot. Who knots a stack of letters they intend to read again? And for some reason, I can't bring myself to cut it. It feels wrong somehow. Like I'm trespassing. Or maybe there's something in there I shouldn't be privy to." He smiled at her. "Now you sound like a character from a mystery novel. I seriously doubt there's anything a boy that age would commit to paper, much less carry around with him, that would be too unseemly." She leaned forward. "There's something else. It's what he said to me at the very last, right before he died." "Now you really are sounding mysterious." She briefly closed her eyes. "He said, 'Mama' . . . I think he must've thought he was speaking to her. He said he'd grieved over how he'd left things between them, but that he didn't take it with him like he'd apparently told her he had." "He didn't take what?" She shrugged. "That's just it. I don't know. He didn't say. But whatever it is, or was, he said he left it there, buried beneath 'the old willow tree.' And then, right before he died, he whispered, 'Somehow it makes dying easier, knowing you'll have it.'" Roland said nothing for a moment, then sighed. "Well, that certainly sheds an interesting light on things, doesn't it?" She nodded, staring at the bundle in his hands. "I think that's why I haven't been able to read these. I feel such a . . ." "Burden?" he supplied. "Yes. And also a responsibility. But the fact that the string is knotted tight . . ." She eyed it as though it were a living thing. "It doesn't make sense, I know." "Do you think maybe one of the doctors gave the boy some medication that caused him to become delusional? Maybe he was speaking nonsense." She shook her head. "The doctors weren't administering medicine to anyone who didn't stand a good chance of living. And he did not." What she said about medication not being administered haphazardly was true. They hadn't even offered him any, until Dr. Phillips ordered it. She looked down at her hands in her lap. "All I know, Roland, is that I can't cut the string. But . . ." She slowly lifted her gaze. "Maybe you could." He raised his brows. "So let me get this straight. You want me to cut the string and open the envelopes so that whatever curse you apparently believe is going to befall the poor, unsuspecting soul who does such will settle on me instead of you. Is that what I'm to understand?" The tiniest smile crept over her face, and she nodded. "Yes. That's pretty much the gist of it." He eyed her for a moment, then gestured. "Hand me that knife on the table over there." **C HAPTER 19** Roland sliced through the knotted string binding the stack of envelopes, sensing Lizzie's trepidation. But being a soldier himself, and carrying his own bundle of letters, he felt at ease with what he was doing. He withdrew the contents of the first of three envelopes and began to read. The handwriting was rather slapdash, so the words were difficult to decipher. "What?" Lizzie whispered, leaning closer. "You're frowning. What is it?" Hearing her increased concern, he couldn't resist egging her on a bit. "Mmmm . . . Lizzie, this is bad." She reached out. "What does it say?" Her hand on his bare arm sent a small thunderbolt through him. It took concentration to continue reading. "It says . . . 'Hayrides. Walks by the creek. Warm biscuits on Sunday mornings. The smell of snow. Melvin, when he burrows down deep beneath the covers with me.'" He lifted his gaze and caught her droll look. "It's some sort of list." Smiling, he scanned the wrinkled, stained piece of paper, then turned it over. The handwriting filled both front and back. He handed it to her, and she read silently, her lips moving. Softness swept her face. "I think it's a list of things he loved." She fingered a dog-eared corner, her tone almost reverent. "Sunsets painted orangey red. A fresh ticked bed and a warm blanket. The feel of mud between your toes come summer. Rain as it sluices off the metal roofing. Mist as it hangs over the hills." Roland loved watching her. She possessed a kind of beauty that only seemed to deepen the more he got to know her. Features he'd thought comely upon first glance—her full lips, the slight up-tilt of her pretty nose, the womanly curves that not even the simplest blue day dress could mask—he now found intoxicating. She finally folded the letter, and he held up the other two envelopes. "Should we?" he asked. She nodded, but made no move to take them. "Since I'm the one already cursed . . . ," he said beneath his breath, satisfied when the comment drew a soft laugh. He opened the second envelope and withdrew a piece of paper similar in appearance to the first, with the same scrawled handwriting. "This one says . . ." Tempted to tease her again, he read the first few lines and all humor fell away. He cleared his throat. "You were right, Mama. This undertaking of mine is far more egregious than my thoughts ever could have conjured. I am not as brave as I once thought myself to be. Before battle commences, in those eternally fleeting moments before the first shot is fired, my bones all but shake free from their joints, and I do not know how my body holds together. I am thoroughly run through with fear. And I am ashamed of being afraid. But I am not the only one. I have seen grown men . . ." He stopped reading aloud. Not that Lizzie would have been offended by the boy's description. He'd witnessed firsthand all she'd been through since the battle that night, and he was convinced there was nothing this woman couldn't endure with grace and dignity. Rather, he'd witnessed the same things the boy was describing and it had moved him just as deeply. She gently tugged the pages from his hand. "'I have seen grown men,'" she continued, her voice a whisper, "'lose the contents of their stomachs, and worse, as the first blast of a Napoleon gun sends a cannonball screaming for the front line. Some men are very shaky. Often they take off running the other way. I have seen more than one officer use his revolver on his own men as they seek to retreat before the battle is fully begun.'" She drew in a slow, painstaking breath, and Roland reached for the pages. But

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a system composed of $N$ distinguishable particles arranged in a chain, each of the particles in the chain is characterized by a binary random variable (this can be, for example, particles with the spin $\frac{1}{2}$). In the aforementioned model it is assumed that spins next to each other are almost always aligned in the same direction. The only exceptions are assumed to be $d$ cases in which the neighboring spins are antialigned. In this model the number of states grows as a power-law, with the corresponding index $q$ being $q_{\mathrm{stat}}=1-1/d$. In addition, the distribution of the total spin of the system in the limit of $N\rightarrow\infty$ tends to a $q$-Gaussian with $q_{\mathrm{dist}}\neq q_{\mathrm{stat}}$. All models in [@Moyano2006; @Rodriguez2008; @Ruseckas2015], except the last model of [@Rodriguez2008] are for $q\leq1$. The distributions of the non-extensive statistical mechanics can be obtained from mesoscopic description of the systems in the form of probabilistic dynamics [@Tsallis2009-1]. Such probabilistic description can be provided by nonlinear Fokker-Planck equations and corresponding nonlinear stochastic differential equations (SDEs) [@Borland1998; @Borland2002], SDEs with additive and multiplicative noises [@Anteneodo2003; @Santos2010] or with multiplicative noise only [@Queiros2007], and with fluctuating friction forces [@Beck2001]. Nonlinear SDEs generating distributions of non-extensive statistical mechanics together with $1/f$ noise have been proposed in Ref. [@Ruseckas2011]. Scaling law that follows from nonlinear Fokker-Planck equations has been recently experimentally confirmed in granular media [@Combe2015]. The goal of this paper is to extend the model presented in Ref. [@Ruseckas2015] by introducing stochastic temporal dynamics. Conserving the total number of domains $d$, we allow spins near domain boundaries to flip. This effectively introduces a random walk of domain boundaries into the previous static model. In the limit of large number of spins we derive the Fokker-Planck equation and a corresponding SDE describing the temporal dynamics of the total spin of the system. The proposed dynamical model provides an insight how a mesoscopic dynamics characterized by the non-extensive statistical mechanics could emerge from a microscopic description of the system. The Letter is organized as follows. To show how stochastic temporal dynamics can be introduced into a model describing the equilibrium, in Section \[sec:uncorrelated\] we introduce stochastic dynamics into a simple model consisting of uncorrelated binary random variables. In Section \[sec:correlated\] we use a similar stochastic temporal dynamics for the model with correlated binary random variables and leading to extensive generalized entropy with $q<1$. In Section \[sec:long-range\] we demonstrate that presence of macroscopic fluctuations in this model can lead to $1/f$ noise, whereas in Section \[sec:subsyst\] we consider properties of a part of larger system. We summarize the paper in Section \[sec:conclusions\]. Stochastic dynamics in the model with uncorrelated binary variables {#sec:uncorrelated} =================================================================== As in Ref. [@Ruseckas2015], we start with the analysis of the dynamical model without any correlations between the particles or their spins. Let us say that we have $N$ particles which have spin projections on certain axis equal to either $-\frac{1}{2}$ or $+\frac{1}{2}$. The microscopic state of such system is fully described by a set of spin projections $\{s_{1},s_{2},\ldots,s_{N}\}$. This system may be treated, in the statistical mechanics sense, using the microcanonical ensemble in which each of the microscopic states is assigned the same probability. Here we obtain the same stationary probability density function (PDF) from the temporal dynamics perspective. We are interested in an observable macroscopic quantity, the total spin of the system $$M=\sum_{i=1}^{N}s_{i}\,.\label{eq:total-spin}$$ Alternatively we can express the total spin as $$M=\frac{1}{2}(N_{+}-N_{-})\,,\label{eq:m-np-nm}$$ where $N_{+}$ is the number of spins with projection $+\frac{1}{2}$ and $N_{-}$ is the number of spins with projection $-\frac{1}{2}$. A sum of $N_{+}$ and $N_{-}$, by definition, should give the total number of spins $N$, $$N_{+}+N_{-}=N\,.\label{eq:n-np-nm}$$ From Eqs. (\[eq:m-np-nm\]) and (\[eq:n-np-nm\]) we obtain relation between total spin and number of particles having certain spin projections: $$N_{+}=\frac{1}{2}N+M\,,\qquad N_{-}=\frac{1}{2}N-M\,.\label{eq:np-nm}$$ To introduce temporal dynamics we assume that during the short time interval $\Delta t$ each spin can flip with the probability $\frac{1}{2}\gamma\Delta t$. If $\Delta t$ is short enough we can assume that only one spin flip takes place during the time interval $\Delta t$. Since each spin can flip independently, the transition probabilities per unit time are $$\begin{aligned} p(M\rightarrow M+1) & \equiv & p^{+}(M)=\frac{1}{2}\gamma N_{-}\,, \label{eq:prob-p}\\ p(M\rightarrow M-1) & \equiv & p^{-}(M)=\frac{1}{2}\gamma N_{+}\,. \label{eq:prob-m}\end{aligned}$$ The transition probabilities $p^{+}(M)$ and $p^{-}(M)$ define a one-step stochastic process and imply the following Master equation for the probability $P_{M}(M,t)$ to find the value $M$ of the total spin at time $t$ [@Kampen2011]: $$\frac{\partial}{\partial t}P_{M}(M,t)=p^{+}(M-1)P_{M}(M-1,t) +p^{-}(M+1)P_{M}(M+1,t)-(p^{+}(M)+p^{-}(M))P_{M}(M,t)\,. \label{eq:master}$$ For large enough $N$ we can represent the dynamics by a continuous variable $x=2M/N$. Using the standard methods from Ref. [@Kampen2011] one can derive the Fokker-Planck equation from the Master equation (\[eq:master\]) assuming that $N$ is large and neglecting the terms of the order of $1/N^{2}$. The resulting Fokker-Planck equation is $$\frac{\partial}{\partial t}P_{x}(x,t)=-\frac{\partial}{\partial x} [\pi^{+}(x)-\pi^{-}(x)]P_{x}(x,t) +\frac{\partial^{2}}{\partial x^{2}}\frac{1}{N}[\pi^{+}(x)+\pi^{-}(x)]P_{x}(x,t)\,, \label{eq:FP-general}$$ where $P_{x}(x,t)=(N/2)P_{M}(Nx/2,t)$ is the PDF of the stochastic variable $x$ and $$\pi^{\pm}(x)\equiv\frac{2}{N}p^{\pm}\left(\frac{Nx}{2}\right)\,.$$ The SDE corresponding to the Fokker-Planck equation (\[eq:FP-general\]) is [@Gardiner2009] $$\frac{dx}{dt}=[\pi^{+}(x)-\pi^{-}(x)]+\sqrt{\frac{2}{N}[\pi^{+}(x)+\pi^{-}(x)]}\xi(t)\,. \label{eq:SDE-general}$$ Here $\xi(t)$ is a white noise with autocorrelation $\langle\xi(t)\xi(t')\rangle=\delta(t-t')$. When the diffusion coefficient depends on $x$, SDE (\[eq:SDE-general\]) should be understood in Itô convention. For the transition probabilities (\[eq:prob-p\]) and (\[eq:prob-m\]), the Fokker-Planck equation (\[eq:FP-general\]) becomes $$\frac{\partial}{\partial t}P_{x}(x,t)=\gamma\frac{\partial}{\partial x}xP_{x}(x,t) +\frac{\gamma}{N}\frac{\partial^{2}}{\partial x^{2}}P_{x}(x,t) \label{eq:FP-1}$$ and Eq. (\[eq:SDE-general\]) takes the form $$\frac{dx}{dt}=-\gamma x+\sqrt{\frac{2\gamma}{N}}\xi(t)\,.\label{eq:sde-1}$$ As one can see from Eq. (\[eq:sde-1\]), the fluctuations of the macroscopic quantity $M$ decrease with the increasing number of spins as $1/\sqrt{N}$ . From Eq. (\[eq:sde-1\]) follows that the average value of $x$ obeys the ordinary differential equation $$\frac{d}{dt}\langle x\rangle=-\gamma\langle x\rangle\,.$$ Thus the deviations from the equilibrium average $\langle x\rangle_{0}=0$ decay exponentially: $\langle x(t)\rangle

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between the *M. cynos tuf* and ITS assays was 0.915 (95% confidence interval: 0.822--1.000). ###### Comparison of *Mycoplasma cynos* quantitative PCR assays using 71 canine respiratory samples. ![](10.1177_1040638719890858-table1) ITS PCR positive ITS PCR negative -------------------- ------------------ ------------------ *tuf* PCR positive 33 2 *tuf* PCR negative 1 35 ITS = in-house *M. cynos* 16S-23S rRNA intergenic sequence qPCR assay; *tuf* = newly developed *M. cynos* qPCR assay. The new *tuf* assay was further scrutinized using 67 isolates that were characterized by *Mycoplasma* spp. culture and sequencing. The results identified 5 true-positive isolates and 56 true-negative isolates. The 56 negative samples were comprised of 22 *M. canis* isolates, 12 *M. felis* isolates, 12 *M. spumans* isolates, 7 *M. edwardii* isolates, and 3 *M. maculosum* isolates. No false-negatives were found, although 6 isolates were determined to be false-positives because they were positive with the *tuf* PCR assay but negative by ISR sequencing. Five of the 6 discrepant ISR sequencing results had *M. canis* and *M. edwardii* as the 2 top BLAST hits, but included *M. cynos* in the list of significant hits. Strains of *M. canis* (ATCC 19525^T^) and *M. edwardii* (ATCC 23462^T^) were tested and both yielded negative results with the *tuf* assay. The sixth discrepant isolate was typed as *M. maculosum* or *M. leopharyngis*, but also included many other significant hits including several that were excluded by testing the ATCC isolates listed above, thus we chose not to pursue this isolate further. Inhibition monitoring {#section16-1040638719890858} --------------------- Continuous monitoring of the XIC did not reveal any systematic indications of inhibition in respiratory matrix, inclusive of tissues, for 22 clinical specimens tested on 15 independent 7500 platform runs ([Fig. 1](#fig1-1040638719890858){ref-type="fig"}). In these specimens, *M. cynos* Ct values were 20.6--40.0; the XIC Ct values were 31.3--35.0. The OA assay detected a range of *M. cynos* Ct values (2.3--18.4) from 23 clinical specimens obtained from 15 independent runs ([Fig. 2](#fig2-1040638719890858){ref-type="fig"}). The XIC was detected in the same specimens and with corresponding Ct values that remained within a span of 2 SDs (Ct range: 10.7--15.8; 2 SD range: 10.7--16.1; [Fig. 2](#fig2-1040638719890858){ref-type="fig"}). ![Detection of *Mycoplasma cynos* target and exogenous internal control in clinical specimens on the ABI 7500 platform (Thermo Fisher Scientific). The cycle threshold (Ct) for each specimen is plotted on the y-axis; no Ct values were \< 20. *M. cynos* was detected over a range of high-, moderate-, and low-positive values (black diamonds; moderate-positive range bracketed by black dotted line) in 22 clinical specimens. Five low-positive values were detected and are plotted above the black dotted line. The MS2 exogenous internal control was detected in the same specimens, and MS2 Ct values remained within a span of 2 standard deviations (gray dots; gray dashed line = 2 SDs).](10.1177_1040638719890858-fig1){#fig1-1040638719890858} ![Detection of *Mycoplasma cynos* target and exogenous internal control (XIC) in clinical specimens on the QuantStudio OpenArray platform (Thermo Fisher Scientific). The cycle threshold (Ct) for each specimen is plotted on the y-axis. A range of high, moderate, and low *M. cynos* positive values was detected in 23 clinical specimens (black diamonds; moderate-positive range bracketed by black dotted line). The MS2 XIC was detected in the same specimens (gray dots; gray dashed line = 2 SDs).](10.1177_1040638719890858-fig2){#fig2-1040638719890858} Sequence confirmation {#section17-1040638719890858} --------------------- To confirm that *tuf* PCR-positive specimens contained *M. cynos*, the ISR was amplified and sequenced. Amplification of the ISR was performed on 107 *tuf* PCR-positive specimens tested in 2017 and 2018, subsequent to the initial set of 71 specimens used to estimate diagnostic performance in 2016. Visualization of the ISR PCR products revealed that 89 *tuf* PCR-positive specimens yielded a single ISR band at the 457-bp size expected for the *M. cynos* genome. The remaining 18 *tuf* PCR-positive specimens yielded 2 bands; one at the size expected for the *M. cynos* genome and a second smaller band ([Fig. 3](#fig3-1040638719890858){ref-type="fig"}). Ninety-four PCR products were purified and were directly sequenced (91 of the amplicon size expected for *M. cynos* and 3 smaller). Of the 91 amplicon sequences expected to be *M. cynos*, NCBI BLAST revealed that 82 were ≥ 99.6% identical to the *M. cynos* ISR sequence, 1 sequence shared high identity with *M. mucosicanis* ISR sequence, and the remaining 8 had poor sequence quality that prevented definitive identification of the *Mycoplasma* species present in the specimen. The *M. cynos* 1642 strain genome sequence (HF559394) includes 3 discrete ISR, 2 of which are 257 bases in length and share 100% identity; the third ISR contains a 1 base insertion. Of the 82 sequences that matched *M. cynos* ISR sequence, 78 of these were 100% identical to the *M. cynos* 1642 strain ISR of 257 bases (HF559394), 2 were 100% identical to the *M. cynos* 1642 strain ISR of 258 bases (HF559394), and 2 were 100% identical to the *M. cynos* 1642 strain ISR of 257 bases (HF559394) except that each had an ambiguous (N) base that could not be resolved manually. The PCR sequence that shared high identity with *M. mucosicanis* strain 1642 sequence (FM180556.1) was identical at 307 of 309 ISR positions. Sequence analysis of the 3 smaller ISR PCR products identified the presence of *M. spumans* (100% identical to AF538684) and *M. canadense* (the most significant BLAST result was to AP014631 with 163 of 169 nucleotide identities; these 2 PCR product sequences were identical); these represent specimens with coinfection of at least 2 *Mycoplasma* species. ![Gel electrophoresis of *Mycoplasma* intergenic spacer region (ISR) PCR products. Most *tuf* PCR-positive clinical specimens yielded a single *Mycoplasma* ISR band at the 457-bp size expected (lanes 1 and 2) for the *M. cynos* genome. A subset of *tuf* PCR-positive clinical specimens yielded 2 bands: one at the size expected for the *M. cynos* genome and a second smaller band (lanes 3 and 4). Lane 5 = negative amplification control. The outermost lanes were loaded with 100-bp DNA ladder (Thermo Fisher Scientific).](10.1177_1040638719890858-fig3){#fig3-1040638719890858} To visualize the evolutionary relationship of the ISR sequences obtained from clinical specimens in the context of previously characterized *Mycoplasma* species, phylogenetic analysis was performed.^[@bibr4-1040638719890858],[@bibr24-1040638719890858]^ Phylogeny of *Mycoplasma* species has been established based on 16S rRNA sequences, and phylogenetic clusters are named after a representative genus or species (<https://www.patricbrc.org/view/Taxonomy/2093>). *M. cynos* ISR sequences were placed within the *M. synoviae* cluster, including those obtained from sequence confirmation of *tuf* PCR-positive specimens (all 82 represented by sequence "Cornell ISR 1"), the *M. cynos* strain Rosendal/H 831^T^ whole genome sequence, and strain C142 ([Fig. 4](#fig4-1040638719890858){ref-type="fig"}). *M. mucosicanis* ISR sequences from PCR and *M. mucosicanis* 1642^T^ GenBank accessions (whole genome sequence SMDN00000000 and intergenic spacer sequence FM180556) were all located in the *M. bovis* cluster. The remaining ISR sequences determined in our study, representing *M. spumans* and *M. canadense*, were present within the *M. hominis* cluster. ![Phylogenetic tree of *Mycoplasma* intergenic spacer region sequences. Evolutionary analyses were conducted in MEGA X, and the tree was inferred

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. Let w(x) be the second derivative of x**3/3 + x. What is w(v(u))? 2*u Let c(l) = -4*l. Let v(q) = 15*q + 2. Calculate v(c(z)). -60*z + 2 Let a(i) be the first derivative of 0*i + 0*i**2 - 3 - 1/3*i**3. Let g(x) = 2*x**2. Calculate g(a(s)). 2*s**4 Let u = 10 + -8. Let m(z) = 0 + 0 + z**u. Let t(f) = f**2 - f - 1. Let o(l) = l + 1. Let k(n) = 3*o(n) + 3*t(n). Determine k(m(g)). 3*g**4 Let m(i) = -63*i - 4. Let k(g) = 2*g. Calculate m(k(r)). -126*r - 4 Let d(x) be the first derivative of -8*x**Janus TiXY Monolayers with Tunable Berry Curvature. Up to now, two-dimensional (2D) materials with both valley polarization and the Rashba effect are still rare. In this work, a new kind of Janus monolayers TiXY (X ≠ Y, X/Y = Cl, Br, I) is demonstrated to have physical properties of benefit for spintronics and valleytronics. In particular, Janus TiBrI shows Zeeman-type spin splitting of 70 meV, large Berry curvature of 106.22 bohr2, and, at the same time, a large Rashba parameter of 147.95 meV Å. On the basis of k·p perturbation theory, we proposed that the Berry curvature can be adjusted by changing the lattice parameter, which will greatly improve the transverse velocities of carriers and promote the efficiency of the valley Hall device. Biaxial strain from -2.5 to 2.5% was applied on Janus TiBrI to verify the theory mentioned above, and a general relationship between the Berry curvature and lattice constant was obtained.Antileukotoxin antibody produced in the bovine lung after aerosol exposure to viable Pasteurella haemolytica. Experiments were performed to determine the in vivo immunogenicity of Pasteurella haemolytica leukotoxin. Calves were exposed twice to aerosol mists of viable P haemolytica, using a treatment regimen previously shown to induce a resistant state. Pulmonary lavage fluids and serum samples from these calves were assayed for leukotoxin-neutralizing antibodies. Before aerosol exposure, neutralizing antibody titers were routinely found in serum samples, but were not detectable in pulmonary lavage concentrates before exposure. After aerosol exposure, titers of toxin-neutralizing immunoglobulin (Ig)A and IgG antibodies were found in pulmonary lavage concentrates and were accompanied by increased serum toxin neutralization titers.Bluemindo Ergonomic and modern music player designed for audiophiles Bluemindo's user interface consists of a main view of all your digitized album discs, which is searchable and filterable. The playback mode is gapless and support ReplayGain (it can also automatically choose to switch between Album and Track modes, depending on the kind of music that's being played). Last but not least, it brings playlist (automatic and user-made), MPRIS/MediaPlayer2 support and lyrics/artwork downloading. It's a free software distributed under GPLv3 terms and written in Python 3.x using GSTreamer 1.x and GTK 3.x.1. Introduction {#sec1} =============== The face of the HIV/AIDS epidemic has changed dramatically since its emergence in the 1980s. Far from its origins as an illness of homosexual men, HIV/AIDS is increasingly affecting women around the world: in 2008, women made up nearly half of the global population of those infected with HIV (15.7 million women, 33.4 million total) \[[@B1]\]. While spread of the epidemic has slowed, addressing the health needs of women infected with HIV remains an important priority. Recent efforts have largely focused on expanding access to HIV diagnosis and counseling, as well as treatment with highly-active antiretroviral therapy (HAART). Providing reproductive health services to women living with HIV is crucial to improving their overall health. Preventing unplanned or mistimed pregnancy allows a woman with HIV to optimize her own health and has the potential to decrease maternal-to-child transmission of HIV. The World Health Organization (WHO) reports that approximately 90% of children living with HIV acquired the infection perinatally---during pregnancy, birth, or breastfeeding \[[@B1]\]. In a model comparing interventions to decrease maternal-to-child transmission (MTCT) of HIV, increasing use of contraception was found to prevent 28.6% more HIV-positive births than increasing use of peripartum nevirapine \[[@B2]\]. Effective contraception thus offers great opportunity to slow the spread of perinatally acquired HIV, though sexual transmission of HIV may still occur between serodiscordant couples. As access to both modern methods of contraception and antiretroviral drugs (ARVs) expands, women with HIV enter the largely uncharted territory of potential drug interactions. In this paper we will summarize the available literature regarding coadministration of ARVs and hormonal contraception, with a focus on whether ARVs lead to alterations in hormonal contraceptive efficacy. Modern hormonal birth control methods available in the United States include daily pills (combined oral contraceptives (COCs) that contain estrogen and a progestin, as well as progestin-only pills (POPs)), a weekly combined hormonal patch, a monthly combined hormonal vaginal ring, injectable depot medroxyprogesterone acetate (DMPA) given every three months, a three-year etonogestrel (progestin) implantable rod, and a five-year levonorgestrel intrauterine system (LNG-IUS). The latter two are often described as long-acting reversible contraceptives (LARCs). All of these methods are highly effective at preventing pregnancy, with the typical-use failure rate ranging from 0.1% (LNG-IUS) to 8% (POPs, COCs, ring) \[[@B3]\]. Hormonal emergency contraceptives (ECs) are also available, which reduce the risk of pregnancy by 89% when taken within 72 hours of unprotected sex \[[@B3]\]. Contraceptive hormones are metabolized by the hepatic cytochrome (CYP) P450 pathway, which is also responsible for the metabolism of many ARVs \[[@B4]\]. Orally administered contraceptive hormones are subject to extensive first-pass gut and hepatic metabolism, which necessitates higher estrogen and progestin doses than those required when these hormones are given via routes that lead to minimal first-pass metabolism \[[@B5]\]. Whether novel delivery systems (i.e., transdermal or transvaginal) affect the pharmacokinetics of contraceptive hormones, and how these drugs will interact with ARVs, remains unclear. It is also uncertain how LARC methods interact with HAART regimens. Contraceptive steroids mainly work by negative feedback inhibition of the hypothalamic-pituitary-ovarian (HPO) axis, with additional effects on cervical mucus and the endometrium. Exogenous estrogen and progestin both profoundly suppress pulsatile secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) \[[@B6], [@B7]\]. However, most of the contraceptive effects (i.e., ovulation suppression, thinning of the endometrium, and cervical mucus thickening) are due primarily to progestin and are dose-dependent \[[@B6], [@B8]\]. Ethinyl estradiol (EE), the estrogenic component of most currently marketed COCs, is primarily metabolized through the hepatic CYP pathway. Specifically, hydroxylation of EE is catalyzed by the hepatic enzymes CYP3A4 and CYP2C9. Wide variation in the levels of these enzymes among individuals is thought to contribute significantly to large intersubject variability of EE pharmacokinetics \[[@B9]\]. The contraceptive progestins available today also vary widely in their metabolism and pharmacokinetics, with large intersubject and intrasubject variability \[[@B10]\]. Modern management of HIV typically involves a combination of ARVs, commonly described as highly active antiretroviral therapy (HAART), since monotherapy can lead to the development of viral resistance to drug therapy. In treatment-naïve patients, a starting regimen typically includes two nucleoside reverse transcriptase inhibitors (NRTIs) and a protease inhibitor (PI), two NRTIs and a nonnucleoside reverse transcriptase inhibitor (NNRTI), or three NRTIs \[[@B11]\]. [Table 1](#tab1){ref-type="table"} lists the five preferred regimens described by the Department of Health and Human Services (DHHS). Ritonavir, a protease inhibitor, is rarely used for its own antiretroviral activity, but is used for its inhibitory effect on CYP3A4, the liver enzyme that normally metabolizes protease inhibitors. A low dose of ritonavir is used to enhance, or "boost," other protease inhibitors, thereby improving ARV efficacy. This paper will examine the available evidence regarding drug interactions between ARVs and all types of hormonal contraception (HC), including transdermal and transvaginal routes as well as LARC options. Pertinent pharmacokinetic (PK) parameters, such as the maximum serum concentration (*C*~max�

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leader who would bring Christian values to the Oval Office because he simply didn't understand them and quite often seemed to be selling the idea that he was faithful the way he might sell Trump Steaks. When speaking at Liberty University just weeks prior to the Iowa Caucus, Trump's salesmanship as a Christian was on full display. At that speech to an assemblage of Liberty University students, who were required to attend, he read from his notes, including a Bible verse from 2 Corinthians 3:17, "Now the Lord is that Spirit: and where the Spirit of the Lord is, there is Liberty." But in what many took as a lack of familiarity with basic Christian parlance, Trump read the book and chapter as "Two Corinthians" instead of the more common "Second Corinthians." Honestly, it was probably just a simple mistake that anyone could have made when reading from notes that had been written by someone else (the notes had been provided by evangelical Tony Perkins, president of the Family Research Council). However, because Trump was already perceived to be falsely selling himself as a fellow Christian just to win the election, the moment seemed like an apt example of his shallow faith. To be clear, questioning the truth of another person's faith is not an action Christians should usually or casually undertake. However, it is also true that one must be vigilant against deception. It does seem worth noting that, regardless of the health of his private relationship with God, Trump's devotion to understanding the tenets of faith appeared Cliff Notes–level at best. Trump's repeated claims that he'd been a church-going Protestant his entire life painted a picture of someone who may very well have clocked in and out of "God time" but also someone who had little genuine interest or curiosity to learn much more than could be picked up by reading a Wikipedia page. Even non-Christians who have been around Christians know some of the basics. It appeared this wasn't true of Trump. When it comes to Christianity, Trump knows the notes but not the tune. When Trump was asked if he'd ever entreated God's forgiveness, the surrounding crowd laughed at the question. They knew it directly challenged Trump's public image as a man who never admitted he was wrong. Trump said, "I'm not sure I have." He went on, "When we go in church and when I drink my little wine . . . and have my little cracker, I guess that's a form of asking for forgiveness, and I do that as often as possible because I feel cleansed." His words exposed his ignorance of both the solemnity of the ritual and its actual theological meaning as an expression of Christ's ultimate sacrifice. What remains depressingly fascinating about Trump is how concerns over his lack of familiarity with or his authenticity on Christian issues are often best illustrated in the way he rejects those very concerns. For instance, after Pope Francis was quoted as saying, "A person who thinks only about building walls, wherever they may be, and not building bridges, is not Christian," most outlets reasonably concluded that he was making reference to Trump's campaign centerpiece: a wall at America's southern border with Mexico. Trump evidently concurred that it was directed at him, and he hit back, saying to a crowd of supporters in South Carolina, "No leader, especially a religious leader, has the right to question another man's religion or faith." Yet, at CNN, they compiled a full history of Trump's calling Barack Obama's faith into question, including saying of Obama's birth certificate, "He may have one, but there's something on that, maybe religion, maybe it says he is a Muslim," as well as tweeting in 2012, "Does Madonna know something we all don't about Barack? At a concert she said 'we have a black Muslim in the White House.'" That same year he also tweeted an article from the conspiratorial website World Net Daily, suggesting a ring President Obama was wearing indicated some sort of Arab origin, saying, "Why does Barack Obama's ring have an [A]rabic inscription," and, after linking the article, adding, "Who is this guy?" It was precisely this type of easily identifiable and seemingly shameless false statements and hypocrisy that continued to make support for him a point of confusion among dissenting evangelicals. But also, sadly, it was a feature that attracted others. As I said earlier, for Christians like myself and some of those quoted here, it was hard to imagine how evangelicals could get truly excited for Trump . . . unless we were simply wrong about what broadly appealed to evangelicals. Guess what? Despite Trump's shaky start in the Iowa Caucus (Ted Cruz won the caucus as well as the evangelical vote), the subsequent primary contests demonstrated that the real estate magnate knew far more about how to appeal to masses of evangelicals than the more traditional evangelical candidates who "spoke the language." At a rally in Iowa in January 2016, Trump told his audience, "Christianity will have power," if he was elected. "Because if I'm there, you're going to have plenty of power. You don't need anybody else. You're going to have somebody representing you very, very well. Remember that." This appeal to powerlessness proved to be devastatingly consequential. It was powerlessness that people felt in Iowa and South Carolina. It was a sense of disenfranchisement that was motivating folks in Texas and Mississippi. For a great many evangelicals, the word _power_ was exactly what they wanted to hear. The idea of having it, and wielding it, was more than intoxicating. It was a lifeline. And in the end, it's what many absolutely believe Trump as president has given them. ## The Shift Trump's acceptance among evangelicals continued to increase as summer approached and his nomination moved toward inevitability. Dissenting evangelicals like myself were faced not only with the looming reality but with the uncomfortable truth that evangelicals had helped put him there. As _Christianity Today_ reported at the time, "Even before the other candidates left the race, Trump was the most frequent choice of all evangelicals, including frequent attendees. Although the levels of support changed according to frequency of attendance, he was still the most frequently chosen in every breakdown in most states." The summer had arrived and the shift had taken place, but the questions, the important questions, are: What happened that precipitated or enabled that change? What took the evangelical movement from questioning and doubting to Jerry Falwell tweets and religious fervor for secular pragmatism? Again, it's utterly essential to keep in mind that until this shift, the doubters and the uncertainty were public and acceptable. And among Christian groups as a whole, as opposed to specifically evangelicals, the acceptance of Trump as "one of us" or even a worthy secular leader was still very much a debatable prospect. In other words, you could still offer dissent or rejection of Trump without being branded an apostate. For instance, after Ted Cruz dropped out and Trump's nomination became certain, the Catholic organization Catholic Vote said the next day in a release, "We will not endorse Donald Trump for President at this time. As much as we oppose Clinton, Trump remains problematic in too many ways to receive our endorsement. With a suspect record, no clear guiding principles, and a history of unpredictability, all we can do for now is take him at his word and hope for the best." This was the kind of statement I would have expected, and I think a great many observers did expect, from most Christian groups. Broadly, it was present and a problem for the campaign. Trump's need to gather support from protestant evangelicals, Catholics, and values voters of all stripes had become increasingly important as the transition to the general election began. This was when he needed the big shift that, we now know, he was able to create. Prior to the summer of 2016, it was by no means assured, or at least was not apparent. In an effort to secure that critical support, candidate Trump held a private meeting with a thousand value-centric conservative leaders in June. Jerry Falwell Jr., whose endorsement in January 2016 had helped identify him as one of Trump's more enthusiastic evangelical surrogates, had this to say: "If we all wait for the perfect candidate who has the demeanor of our pastors and agrees with us on every issue, including our personal theological beliefs, then we may all sit at home on election day for the rest of our lives. How many of you can honestly say that you even agree with your spouse on everything?" That was the frame, and that meeting was when the evangelical attitude toward Trump transitioned from "peculiar to a subset of Christian voters" to "the way things are." The importance of the meeting was lost on no one. Penny Nance clarified the purpose and significance, saying of Trump, "He needs to win our hearts." Evangelical figure Michael Farris, chairman of the Home School Legal Defense Association, who was not invited to the meeting, offered a very pessimistic view. He had been specifically told by one of the meeting's organizers that he was not invited because he'd been too "anti-Trump" up to that point. On the day of the event, Farris had an op-ed in the _Christian Post_ in which he referenced his participation long ago at the very first meeting of Falwell Sr.'s Moral Majority back in 1980. He made a remarkable point: > The premise of the meeting in 1980 was that only candidates that reflected a biblical worldview and good character would gain our support. Today, a candidate whose worldview is greed and whose god is his appetites

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immobilizera immobilizer NOUN subst:sg:gen:m3 Animacy=Inan|Case=Gen|Gender=Masc|Number=Sing 1 nmod _ _ 3 to to AUX pred _ 4 cop _ _ 4 wydatek wydatek NOUN subst:sg:nom:m3 Animacy=Inan|Case=Nom|Gender=Masc|Number=Sing 0 root _ _ 5 około około PART qub _ 7 nmod _ _ 6 kilkuset kilkaset DET num:pl:gen:m2:congr Animacy=Nhum|Case=Gen|Gender=Masc|Number=Plur|NumType=Card|PronType=Ind 7 det:nummod _ _ 7 złotych złoty NOUN subst:pl:gen:m2 Animacy=Nhum|Case=Gen|Gender=Masc|Number=Plur 4 nmod _ SpaceAfter=No 8 . . PUNCT interp _ 4 punct _ _ ~~~ ~~~ conllu # visual-style 22 bgColor:blue # visual-style 22 fgColor:white # visual-style 18 bgColor:blue # visual-style 18 fgColor:white # visual-style 18 22 det:nummod color:blue 1 Sprytny sprytny ADJ adj:sg:nom:m1:pos Animacy=Hum|Case=Nom|Degree=Pos|Gender=Masc|Number=Sing 2 amod _ _ 2 oszust oszust NOUN subst:sg:nom:m1 Animacy=Hum|Case=Nom|Gender=Masc|Number=Sing 4 nsubj _ _ 3 jest być AUX fin:sg:ter:imperf Aspect=Imp|Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin 4 cop _ _ 4 przekonujący przekonujący ADJ adj:sg:nom:m1:pos Animacy=Hum|Case=Nom|Degree=Pos|Gender=Masc|Number=Sing 0 root _ SpaceAfter=No 5 , , PUNCT interp _ 8 punct _ _ 6 swym swój DET adj:pl:dat:f:pos Case=Dat|Gender=Fem|Number=Plur|Poss=Yes|PronType=Prs|Reflex=Yes 7 det _ _ 7 ofiarom ofiara NOUN subst:pl:dat:f Case=Dat|Gender=Fem|Number=Plur 8 iobj _ _ 8 proponuje proponować VERB fin:sg:ter:imperf Aspect=Imp|Mood=Ind|Number=Sing|Person=3|Tense=Pres|VerbForm=Fin 4 conj _ _ 9 pozostawienie pozostawienie NOUN ger:sg:acc:n:perf:aff Aspect=Perf|Case=Acc|Gender=Neut|Number=Sing|Polarity=Pos|VerbForm=Vnoun 8 obj _ _ 10 obrączki obrączka NOUN subst:sg:gen:f Case=Gen|Gender=Fem|Number=Sing 9 obj _ _ 11 lub lub CCONJ conj _ 14 cc _ _ 12 innej inny ADJ adj:sg:gen:f:pos Case=Gen|Degree=Pos|Gender=Fem|Number=Sing 14 amod _ _ 13 bezwartościowej bezwartościowy ADJ adj:sg:gen:f:pos Case=Gen|Degree=Pos|Gender=Fem|Number=Sing 14 amod _ _ 14 rzeczy rzecz NOUN subst:sg:gen:f Case=Gen|Gender=Fem|Number=Sing 10 conj _ _ 15 w w ADP prep:acc:nwok AdpType=Prep|Case=Acc|Variant=Short 16 case _ _ 16 zastaw zastaw NOUN subst:sg:acc:m3 Animacy=Inan|Case=Acc|Gender=Masc|Number=Sing 9 nmod _ _ 17 i i CCONJ conj _ 18 cc _ _ 18 zwrot zwrot NOUN subst:sg:acc:m3 Animacy=Inan|Case=Acc|Gender=Masc|Number=Sing 9 conj _ _ 19 gotówki gotówka NOUN subst:sg:gen:f Case=Gen|Gender=Fem|Number=Sing 18 nmod _ _ 20 za za ADP prep:acc AdpType=Prep|Case=Acc 22 case _ _ 21 kilkadziesiąt kilkadziesiąt DET num:pl:acc:f:rec Case=Acc|Gender=Fem|Number=Plur|NumType=Card|PronType=Ind 22 det:numgov _ _ 22 minut minuta NOUN subst:pl:gen:f Case=Gen|Gender=Fem|Number=Plur 18 det:nummod _ SpaceAfter=No 23 . . PUNCT interp _ 4 punct _ _ ~~~ The inhumanity of this is staggering. The evil of it is off the charts. This is the regime that Barack Hussein Obama empowered and enabled and showered billions of dollars upon. This is the regime that the Democrats are intent upon propping up. There are courageous Iranians now who are increasingly open about their opposition to the brutal and bloody mullahs, and they deserve all the support we can possibly give them. The idea that any country in the world would respond to this regime and all of its institutionalized savagery with anything but contempt and revulsion is breathtaking. “IRGC Strategist Hassan Abbasi Praises Iranians Who Handed Over Their Own Children for Execution for Opposing the Regime, Says: 2,300 Iranians Were Killed in Syria War,” MEMRI, February 6, 2019: IRGC strategist Hassan Abbasi said in a February 6, 2019 interview on Ofogh TV (Iran) that guarding the Islamic Republic is a top priority, even if he disagrees with some of the laws or if the law would require him to be sentenced to death. Abbasi and the interviewer praised people who handed their own children over to be executed for opposing the Iranian regime. Abbasi also said that Iran’s pinnacle of achievement is raising and educating valiant young men to the level that they are willing to martyr themselves for the regime. Following are excerpts: Hassan Abbasi: I have been jailed in the Islamic Republic several times, but we consider the guarding of the Islamic Republic to be our top duty. The Islamic Republic has laws. Even if you and I do not agree with the law, we still must follow it. Even if, according to the laws of the Islamic Republic – laws that we might consider to be defective or limiting… Even if, according to the law, someone like me is sentenced to death… [Even if this were to happen,] as far as I am concerned, guarding the Islamic Republic is my top-most duty. Guarding the regime of the Islamic Republic, guarding the legislative branch, guarding the executive branch, guarding the judicial branch, guarding the different bodies, the public, the country, its territorial integrity… All these things are considered to be the pillars of guarding the regime. Interviewer: You said: “Even if I am executed” – I’d like to say that it is inconceivable [that this would happen to you]. This sentence is a bit exaggerated… Hassan Abbasi: I said: “Even if.” Interviewer: I recall that since the beginning of the Revolution, some of the great people in this regime… With their own hands… Some people have executed their own children. Yes. They handed their own children over to the firing squad – this is incredible! Hassan Abbasi: There were mothers whose children were being executed for opposing the regime, and

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angoon told The Irrawaddy the case of a 7-year-old girl, who was brought to her clinic by her mother after an extended period of vaginal bleeding. The mother thought she had begun menstruating, but the checkup revealed the girl had been raped. “But the mother could not believe it,” she said, adding that parents often did not want to accept their children had been subjected to such a heinous crime. Meanwhile, those subject to attacks suffer from lifelong trauma, chronic health problems, and in the worst cases, die from their injuries. Not Safe with Neighbors It remains customary for ordinary mothers and fathers in Burma to trust their neighbors with the care of their children, particularly in rural areas where older members of the community need to work the land. Yet in almost all cases of child sex abuse, particularly those widely reported on in recent months, neighbors are the alleged perpetrators. Reported cases of immediate family members abusing their young siblings or children are also on the rise. In two separate cases in Moulmein, a girl under the age of four and a five-year-old girl were sexually assaulted by their neighbors. Both perpetrators came before the same judge. Both men were immediately granted bail. In one harrowing instance, a 14-year-old girl was abducted from her home in Mon State’s Kyauktan village and taken to a house in the border town of Myawaddy, where she was shackled and raped repeatedly over four days. Her kidnapper remains at large despite her rescue. In October and November, the rape of two girls aged four and eight in separate cases sparked an outburst of public anger in Sittwe. One of the perpetrators was serving as a soldier in the Burma Army, while the other had recently deserted. Both victims died from their injuries. The perpetrator in one case was quickly handed over to a military tribunal, which quickly sentenced him to 12 months in prison. Following a riotous protest outside Sittwe’s central police station, the accused is now before a civilian court. Khin Than Htwe, a community worker in Moulmein, told The Irrawaddy the case of a young girl repeatedly raped by her older brothers in Mon State’s Nyaung Gone village, who were sentenced to only five months’ imprisonment. “There is no protection for her. She had to live with her brothers again after that,” she said. Law Favors Culprits Sexual abuse of young children are the most common rape cases, according to police records published in local media. In Burma, children under 14 are afforded a wide range of legal protections under the Child Law, but there are little or no legal protections for children vulnerable to abuse. Aye Nu Sein, a Sittwe-based lawyer and vice-chair of the Arakan National Party (ANP), pointed out that there is no difference in charges or sentencing between those rapists who attack adults and those who sexually abuse children. A handful of lawyers, politicians and activists have called for legal reform to increase sentences for those who engage in child sexual abuse, but so far, attempts to legislate harsher punishments for perpetrators have failed. Part of the reason for the deadlock could be attributed to the demands of the more strident campaigners, including a concerted push to mandate the death penalty, a demand from which incumbent lawmakers have quietly recoiled. Outgoing lawmaker Thein Nyunt of the New National Democracy Party has spent years campaigning for an increase in prison sentences and the imposition of capital punishment for child sex abusers, a view he reiterated to The Irrawaddy. “There have been many things we have done to prevent sexual assault of children, but cases have increased,” he claimed. “We must prevent it by trying to put fear in the perpetrators. Therefore capital punishment should be imposed. One punishment could prevent at least 20,000 children from being sexually assaulted.” Thein Nyunt’s views appear to be gaining traction. Kyaut Sein, a social activist helping the families of the victims in Sittwe, is outraged at the lenient sentence handed recently handed down by the military court. Echoing widespread sentiment in the town, she agreed that perpetrators guilty of child sexual abuse should be subjected to capital punishment. “The death penalty should be given to those rapists, to prevent further rapes against the children,” she said. Lawyer Robert San Aung, noted for his involvement as defense counsel in a number of high profile human rights cases, agreed that execution was a just punishment for the crime, citing the need for a strong deterrent to protect Burma’s “stability”. “As cases of rape against young children are on the increase, harsh punishment is desperately needed,” he told The Irrawaddy. “It seems we have to accept capital punishment. The more the increase in the child sexual assault, the more it will impact on the stability of the country.” Others, while conceding the need for stronger punishments, stopped short of supporting mandatory capital punishment, saying that more focus was needed on prevention mechanisms and awareness. “The death penalty is a strong word, said Htoot May, an ANP member recently elected to an Upper House seat in Arakan State. “We need to protect our children, and we need stronger laws to do that.” Khin Oo Tha contributed to this report.Sources: Wrigley Renovation Deal Could Be Done By Home Opener Sources: Wrigley Renovation Deal Could Be Done By Home Opener The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports. The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports. The Chicago Cubs and their Wrigleyville neighbors appeared close to an agreement Tuesday to give Cubs owners the green light for their planned renovation of the team's landmark stadium. CBS 2 Chief Correspondent Jay Levine reports.sleep 1 t cal -de 4 /* * DO NOT ALTER OR REMOVE COPYRIGHT NOTICES OR THIS HEADER. * * Copyright (c) 2019-2020 Payara Foundation and/or its affiliates. All rights reserved. * * The contents of this file are subject to the terms of either the GNU * General Public License Version 2 only ("GPL") or the Common Development * and Distribution License("CDDL") (collectively, the "License"). You * may not use this file except in compliance with the License. You can * obtain a copy of the License at * https://github.com/payara/Payara/blob/master/LICENSE.txt * See the License for the specific * language governing permissions and limitations under the License. * * When distributing the software, include this License Header Notice in each * file and include the License file at glassfish/legal/LICENSE.txt. * * GPL Classpath Exception: * The Payara Foundation designates this particular file as subject to the "Classpath" * exception as provided by the Payara Foundation in the GPL Version 2 section of the License * file that accompanied this code. * * Modifications: * If applicable, add the following below the License Header, with the fields * enclosed by brackets [] replaced by your own identifying information: * "Portions Copyright [year] [name of copyright owner]" * * Contributor(s): * If you wish your version of this file to be governed by only the CDDL or * only the GPL Version 2, indicate your decision by adding "[Contributor] * elects to include this software in this distribution under the [CDDL or GPL * Version 2] license." If you don't indicate a single choice of license, a * recipient has the option to distribute your version of this file under * either the CDDL, the GPL Version 2 or to extend the choice of license to * its licensees as provided above. However, if you add GPL Version 2 code * and therefore, elected the GPL Version 2 license, then the option applies * only if the new code is made subject to such option by the copyright * holder. */ package fish.payara.microprofile.faulttolerance.policy; import static org.junit.Assert.assertEquals; import java.lang.reflect.Method; import org.eclipse.microprofile.faulttolerance.ExecutionContext; import org.eclipse.microprofile.faulttolerance.Fallback; import org.eclipse.microprofile.faulttolerance.FallbackHandler; import org.junit.Test; import fish.payara.microprofile.faulttolerance.service.FaultToleranceServiceStub; import fish.payara.microprofile.faulttolerance.test.TestUtils; /** * Tests the basic correctness of the {@link Fallback} handling. * * @author Jan Bernitt */ public class FallbackBasicTest implements FallbackHandler<String> { /** * Most basic case where annotated method fails and the fallback returns a result (no method arguments) */ @Test public void fallbackMethod( ) throws Exception {

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Let t be n(1). Let r be (-13 + 1*-2)*t/15. Solve -5*x = -4*v + r, -5 = -v + 6*x - 3*x for v. 5 Let p = -4905 + 4907. Solve 2 = d, 2*u + p = 5*u + d for u. 0 Suppose 4*c - 2*l - 14 = -2, -2*l + 12 = 2*c. Suppose 5 = 3*v - c. Suppose -6*y + v = 3. Solve 4*s - 20 = y, -3*s = -f - 0*f - 15 for f. 0 Let b be (-1)/3*1 - 10/(-3). Suppose -b*t - y = 1, 3*y + 4 = 4*t - y. Let z be (11 - 6) + (-2 + 2 - 1). Solve -z*x + t - 12 = 0, -l = -x for l. -3 Let q = 6084 - 6081. Solve c - q = -17*y + 20*y, -3*c = 9 for y. -2 Let l(u) = u**2 - 22*u - 73. Let t be l(25). Suppose -5 = -t*f + 3, 0 = -3*v + 4*f - 1. Solve 4*w - 4*r + 2 = -10, 0 = v*w + 5*r - 15 for w. 0 Let h(a) be the first derivative of 12*a - 10 + 9*a - 4*a - 3*a + 2*a**2. Let d be h(0). Solve 0 = 4*s - 5*c + 22, 0*s + 4*c = 2*s + d for s. -3 Let v be ((-4)/9)/(9 - 166/18). Solve 5*a + 0*a - v*g + 30 = 0, -g + 13 = -2*a for a. -4 Let q = -1 + -1. Let l be (4 + (12 - -1))*(q + 5). Let u = l - 49. Solve -4*w - 18 = 5*d, 3*w = u*d + 1 - 3 for w. -2 Let m(u) = -14*u + 7. Let r(a) = -12*a + 6. Let s(h) = 5*m(h) - 6*r(h). Let d be s(2). Solve -d*g + 8 = -k - k, -k = g - 6 for g. 4 Suppose 2*y + 24 = 4*a - 2*y, -6 = -5*a - 3*y. Solve i + i - 17 = a*g, -4*i + 4 = 0 for g. -5 Let z(h) = 518*h + 3629. Let g be z(-7). Solve -g*y - 93 + 112 = -2*s, y = 3 for s. -5 Suppose 0 = 4*i + 4*n - 2*n + 22, -2*i - 3*n - 21 = 0. Let p be 4 - (4 - (3 + i)). Suppose 0 = -p*m + m. Solve -3*l + 3*c = m, 5*l = -2*c - 5 - 2 for l. -1 Let s(v) = -5*v - 20. Let a be s(-4). Suppose 5*n + 3*t + t = a, 3*t = 0. Solve -3*f - 12 = -4*l - n*l, 3*l - 8 = 2*f for f. -4 Suppose 0 = 22*y - 101 - 119. Suppose -y*v + 4 = -56. Solve 2*w - 8 = 0, w - 19 = v*k - k for k. -3 Suppose -7*l - 3*l + 400 = 0. Let m be (-4)/(l/25)*-6. Solve 0 = -5*b + 5*f - m, -b + 5*f + 9 = 24 for b. 0 Let l(c) = -7*c**2 - 282*c - 78. Let p be l(-40). Solve -4*n = -2*t - p, -7*t + 0*n = 3*n - 44 for t. 5 Let y be (2*-1)/(-2) - -21. Suppose 3*o = -25 + 88. Suppose -3*k - 3*i + o = 0, -4*k + 24 = -k + 4*i. Solve -k*x + 2 = -5*x, y = -4*n - 3*x for n. -4 Let y = 28 + -17. Let x be ((-1)/3)/((-29)/435). Suppose x*u - 48 = -u. Solve -2*z = -3*n - y, z + 2*n = 3 - u for z. 1 Let j(s) = -s**3 - 6*s**2 - 6*s. Let k(r) = -6*r - 30. Let n be k(15). Let u = n + 115. Let w be j(u). Solve 0*x - x - w*g = -7, 4*x = 5*g - 22 for x. -3 Suppose -8 = -3*z + 4*z. Let d be (-10)/z - 2/((-16)/6). Suppose 0 = -u - 2*t - 8, 3*u - 26 = -t + 5*t. Solve -d*n - 3*c = 1, -3*c = -n + 2 + u for n. 1 Suppose 0 = 4*y + 21 + 59. Let q be ((-22)/(-4))/(y/(-40)). Solve q*u - 6*u - 5 = 5*b, 3*u - 11 = b for b. 4 Let v(g) = 47*g**2 - 41*g + 26. Let l be v(1). Solve 30*f - l*f - 2*m - 16 = 0, -4*f = -m + 7 for f. -3 Let y be (-1)/(-2 + 10/6). Suppose 2*k - k - 4 = 0. Let w be 20/55*121/22. Solve -y = -k*v - q - 2*q, -4*v + w = 2*q for v. 0 Let o be -2 + 63/13 + 26/169. Let z(a) = -a**3 + 2*a**2 + 5*a - 4. Let b be z(o). Solve -3*x + 25 = -g + 6*g, b*g = -x + 10 for x. 0 Suppose 0 = l - 5*m - 25, -3*l - 42*m = -36*m + 30. Solve 3*f - 4*g + 44 - 58 = l, f - 18 = 4*g for f. -2 Suppose 2*u + 25 = -5*g + 208, -3*g - u + 109 = 0. Let v(f) = -f**3 + 35*f**2 + 40. Let i be v(g). Solve -5*j - i = -0*j - 5*m, 3 = -3*j - 4*m for j. -5 Suppose 9*p - 71 = 64. Let w = -5 - -9. Suppose -3*f - f = -3*y - 17, -w*f + 5*y = -p. Solve 22 = 2*o - 3*m + 7, 0 = f*o + 2*m + 10 for o. 0 Let d = -272 - -283. Let f(k) = k**2 - 15*k + 44. Let z be f(d). Solve 5 = -g - a, g + 2*a + 2*a + 17 = z for g. -1 Let i = -167 + 169. Suppose 0 = 2*k - i*a + 2, 12 = 5*k + 2*a - 11. Solve u + 12 = -k*b, u - 4*b = -3*b + 8 for u. 3 Let l(g) = -g - 16. Let d be l(-18). Let t be 1*(-3 + d) + 2. Suppose 4*z = 3*z + t. Solve h = 2*j - 2*h + z, -4*j + 2*h - 6 = 0 for j. -2 Let i(r) = r**2 + 7*r - 44. Let u be i(4). Suppose 4*c - w - 3*w - 32 = 0, c - 5*w = u. Solve -3*x + 5*b + c = 4*b,

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was alone when he was shot. Neighbor Jean Petry saw Pace’s mother and sister trying to comfort him before the paramedics arrived. “For a 16-year-old boy to be shot — I just can’t imagine,” Petry said. “It could have been one of my own.” Pace was taken to UPMC Mercy Hospital in critical condition where he was pronounced dead. Police have not yet established a motive. “Apparently, there were two if not three blacks males that approached him and one of them pulled a gun out and fired at least three shots at him,” Lt. Hermann added.Petty Harbour–Maddox Cove Petty Harbour–Maddox Cove is a town of approximately 960 people located on the eastern shore of the Avalon Peninsula in the province of Newfoundland and Labrador, Canada. It is nestled deep in the heart of Motion Bay, just south (approximately 15 minutes away) of St. John's. The present town is approximately 200 years old, though the site has been continuously occupied since at least 1598, predating the arrival of the Mayflower and making it one of the oldest European settlements in North America. During King William's War, the village was raided by French forces in the Avalon Peninsula Campaign. Petty Harbour–Maddox Cove is the site of the Petty Harbour Generating Station, the first hydroelectric generating station in Newfoundland and Labrador. It was also the Tidy Towns population category winner for 2007. This award is based on natural beauty, community involvement, environmental awareness and Heritage preservation. Etymology The name "Petty Harbour" is the anglicized form of the French name "Petite Havre" meaning Small Harbour. History By 1500 "Pettite Harbour" was probably already a regular seasonal base for the Basque fishery, and by the 1600s the English had taken it over. Richard Whitbourne records a decisive "set-to" between English, who were probably royally licensed privateers, and Portuguese at "Petyte Harbour" in 1619. An excellent base for pirates, Petty Harbour afforded a good hiding place for their small ships, intent on attacking vessels approaching St. John's (as late as 1791 two Yankee privateers were captured there). In 1621 control of Petty Harbour was shared by William Vaughan, George Calvert, and the London and Bristol Company, although none of these absentee owners attempted settlement or regulation of the fishery. In 1637 David Kirke's settlement brought by-boat keepers (landowners who hired fishing servants) to Petty Harbour, and this practice continued after the settlement attempt failed. The anglicized spelling of the place name was soon established - in his 1604 Journal, James Yonge records a journey overland from St John's to "Petty Harbour” to “look after our men". From this period until the nineteenth century, the economy of the area was dominated by "Newman and Company”, a West Country firm, which owned and rented out most of the land and controlled trade. From 1664 to 1850 the Newman and company, and English West Country owns most of the lands and controls the trade in the fishery. Though the migratory fishing interests discouraged settlement, “Berry’s List" of 1675 records 5 planters 3 wives, 1 child, 39 servants, 10 boats, 4 stages, 3 vats and 6 cattle. Early settlement was, however, subject to difficulty and danger. From 1676 to 1678 migrant fishermen seasonally razed settlers' houses and premises. The presence of this settled fishery so close to St. John's was a red flag to migratory fishermen anxious to protect their privilege of "freedom of fishing" and in 1676 and 1678 rooms at Petty Harbour were destroyed by crews of fishing ships. In 1696 Petty Harbour was attacked and destroyed by the French. Lemoyne D'Iberville met his first resistance from 30 fishermen from Petty Harbour, who retreated behind the Petty Harbour River to a trench they had constructed. The fishermen were quickly overwhelmed by the soldiers, but managed to inform St. John's of the invasion. Two days later a force of 80 men sent out from the capital were also handily defeated by the French. Some 36 fishermen were killed in the battle and others were taken prisoner. When the French confronted the small winter garrison at St. John's, they scalped one prisoner, William Drew, to strike terror into the hearts of the St. John's men and the capital surrendered. Daniel d'Auger de Subercase assembled a group of raiders composed of Mi'Kmaq and Canadians from Québec to help in the campaigns against British settlements. They captured Bay Bulls and Petty Harbour in January 1705 and then marched on St. John's. In 1789 the brig Duke of Leinster arrived in the night leaving 12 women and 102 boys in Bay Bulls and Petty Harbour. These were Irish convicts whose original destination was Australia, but with high shipping costs, Newfoundland was deemed a more economical place. Increases in crime and typhus in St. John's lead to the deportation of the convicts back to Dublin three months later. In August 1796 a French squadron under Admiral de Richery threatened St. John's and destroyed the settlement of Petty Harbour and Bay Bulls, seriously disrupting the bank fishery. Nevertheless, settlement gradually increased. As the by-boat keepers, who settled the southside due to its favorable winds for drying fish, were mostly English and Protestant, and the Irish, who were forced to settle the north side, were chiefly Roman Catholic, the community was accidentally segregated on sectarian lines from an early time. The 1794-95 census records a population of 255 in 50 households, with 16 "heads of households" Newfoundland-born. There were 133 Protestants and 122 Catholics. Prominent surnames included Angel, Chafe, French, Kennedy, Matthews and Welsh. Most people were occupied in the fishery, and there were two carpenters, two coopers, two laundresses and a surgeon. A Church of England church as built about 1800, and a Roman Catholic church in 1832. By 1857 Petty Harbour's population had risen to 747 (29 of whom were born in Ireland and 22 in England), nearly twice as many Catholics as Protestants. There were two churches, over 100 dwellings, two schools with some 105 pupils, premises for salting fish and three cod oil factories. Education was in the charge of the interdenominational Newfoundland School Society. In addition to the three R's, sewing and knitting were offered for girls and net-making for boys. One of Newfoundland's best known folk songs - the Petty Harbour Bait Skiff was written about Petty Harbour men who drowned in June 1852, while returning from Conception Bay with a load of bait. It was composed soon after the tragedy by John Grace of St. John's, where there was "crying and lamenting in the streets" on learning of the fate of Skipper John French and his crew "all on the eighth of June". Only one of the crew, "young Menshon", was saved by "Jacob Chafe that hero brave." By the 1850s the population (747 inhabitants) had begun to exceed the capacity to support it: shore space and housing sites were taken up, and the wood supply was exhausted. Some residents moved inland to Doyles and the Goulds to supplement their earnings by logging and farming. When it became clear that the growing population could not be sustained even by these measures other people began to move, first to nearby Maddox Cove and then to the arable farmland of the Goulds. While the Goulds formed its own community, Maddox Cove continued its close connection with Petty Harbour. With new room for expansion of the population of Petty Harbour (now usually counted to include Maddox Cove) continued to grow, reaching 1053 in 1891. This increase in population can be partly attributed to a new wave of Irish immigrants who settled in Maddox Cove. Prominent surnames in Maddox Cove included Chandler, Drake, Hanniford, Healey, Heffernan, Madden & O'Brien. At this time 60% of the residents were Roman Catholic, 30% Church of England and 10% Presbyterian; and 250 students attended four schools. The turn of the century saw changes in the community's economy and character. In 1898 the Reid Newfoundland Company built Petty Harbour Generating Station Newfoundland's first hydro-electric generating station. It began operation on April 19th 1900, delivering power for St. John's streetcar system and commercial lighting. This brought alternative employment to the area, as well as relatively cheap electricity, but controlling the water supply created practical difficulties and health problems. At this time, with the Goulds woodlands depleted, the sawmills at Petty Harbour closed. The 1909 rail link between St. John's and Trepassey increased contact with St. John's, and the 1932 road made feasible daily commuting to the city for wage work - a practice that has grown in importance to the community. Petty Harbour-Maddox Cove were incorporated in 1969. In the late 1970s local improvement programs led to a revitalization of the local community by funding expansion and modernization of the fish plant and the installation of water and

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predictor, at time $t''$, to forecast the usage of System A for the future time $t$. In this paper, we specifically consider predicting traffic congestion at a morning time $t$, using household-level electricity usage data during the time interval $[t',t'']$ that can be up to a few hours earlier than $t$ on the same day. As we will show later, this predictor can outperform a predictor using only the traffic data, even at the time much closer to $t$ than $t''$. This is because morning traffic break-down is largely attributed to random demand characteristics, such as demand level, driving behavior, departure time from home, etc. Those demand characteristics can hardly be predicted using traffic data only in the real time, and oftentimes the traffic break-down may occur in the morning peak without sufficient prior signs from traffic data. Our hope is that electricity use at midnight or in the very early morning can partially reveal those demand characteristics to some extent, and therefore can help better predict traffic congestion for some locations. Consider electricity use data at the household level. On each day, $e^d_h(t)$ denotes the electricity use at time of day $t$ on day $d$ for the $h$-th household. Suppose we collected data for $H$ households, $D$ days, and $T$ time-of-day intervals. $e^d_h\doteq \{e^d_h(t)\}_t$ is a $T\times 1$ vector, also known as a daily **profile** of electricity use on day $d$ for the $h$-th household. There are in all $DH$ daily profiles. Similarly, $e^d\doteq \{c^d_h\}_h$ is a $TH\times 1$ vector, namely daily observations for electricity use. We intend to predict both “congestion starting time” and “congestion duration” on a road segment, denoted by $k^d$ and $c^d$ on day $d$, where both $k^d$ and $c^d$ are at a much later time than those $T$ time intervals of electricity use observations. Our goal is to establish, $$\label{pred} k^d = f(e^d;\beta), c^d = f'(e^d;\beta')$$ Where $f(\cdot)$ and $f'(\cdot)$ is a model mapping electricity use to congestion starting time and duration, respectively, and $\beta,\beta'$ are a vector of parameters to be learned from data. The intuition behind $f(\cdot)$ and $f'(\cdot)$ is that electricity use from midnight to 5:30am may reveal demand characteristics, namely what time, and how many travelers depart home for work. For instance, electricity use of a household drops when family members go to sleep, or it drop when they depart home. However, due to complicated spatio-temporal relationship among electricity use and transportation system use, $f(\cdot), f'(\cdot)$ are generally unknown and difficult to construct using real-world physics. Therefore, we use data mining models (i.e., regression models) to estimate $\theta,\theta'$ for assumed functions $f(\cdot)$ and $f'(\cdot)$. There are many different ways to construct functions $f(\cdot)$ and $f'(\cdot)$. Complicated data mining models such as Neural Networks can deal with high dimensional data, but can be notoriously difficult to interpret. In order to obtain insights regarding cross-system interrelations, in this paper, we use simple linear predictors in conjunction with an unsupervised learning approach. Clustering ---------- We suppose there exist some typical profiles of the electricity use, namely **daily patterns**, that characterize individuals and their daily activities. It is expected the influence of each pattern of individuals and their daily profiles to the traffic congestion is stable from day to day, and can be mined using historical data. Some intuitive examples include, - One daily pattern could be that there is a spike of electricity use from midnight to 2am, while the use is low during the morning til 6am. This implies that the group of users under this pattern may not commute during the morning peak, and therefore they tend to not contribute to the congestion. - A second daily pattern could be that electricity use of a user is low from midnight to 5:30am, followed by a rise after 5:30am. This is perhaps a typical “morning commute” pattern for a typical commuter. - Another daily pattern may be that the electricity use steadily declines over time from midnight to 5:30am, as a result of air conditioning running all night during the summer. Then the use rises at 5:30am for commuters’ morning activities. Some daily patterns are straightforward to relate to users’ activities. However, electricity use can be attributed to many other factors that are random, noisy, and hard to interpret. Therefore, we use a data-driven approach to separate observations into “clusters” or “typical patterns” that are representative of typical electricity use among all sampled users. The increase and decline of electricity use over time for all patterns will be determined by the statistical models rather than manual specifications. Another note to make here is that a user can switch among those typical patterns from day to day. A user may be a commuter, namely under a typical commuter daily pattern, from Mondays to Thursdays, while behaving under a non-commuting daily pattern on Fridays. She does not contribute to the morning-peak congestion on Fridays. We would like to use data mining models to capture the characteristics of individuals and their patterns on each day, both of which are used to predict morning congestion. In this paper we use the simple k-means clustering algorithm to learn daily patterns. We have $H$ households and their daily profiles of $D$ days, in all $DH$ samples: $\{e_h^d\}_{d,h}$. We partition the samples into $K$ clusters (or typical patterns) denoted as pattern $1$, pattern $2$, ... , pattern $K$. Each pattern $i$ is represented by the centroid of its cluster (usually the numerical average) $e_i$. The number of clusters $K$ must be predefined before performing the clustering. The GAP statistics ([@tibshirani2001estimating]) can be used to determine the value of $K$. A linear predictor ------------------ We assume that congestion starting time on the $d$-th day is predicted by its expected value that is a linear combination of many features, $$\begin{aligned} \mathbb{E}(k^d) = \beta^T x^d $$ Where $x^d$ is a vector of $p$ features observed on the $d$-th day. $x^d = [x_1^d,x_2^d,...,x_p^d]$. Those features are derived from daily profiles $e^d$. The commonly used ordinary least square (OLS) linear predictor is to learn the parameters $\beta$ such that $$\begin{aligned} \min_{\beta} ||k-x^{\top}\beta||_2\end{aligned}$$ However, if the dimension of $x$ becomes very large or larger than the sample size, then the regression tends to overfit the data. To overcome this issue, we use both L1-norm penalization and cross validation. The first idea is to add a L1-norm regularization of $\beta$ (LASSO, [@tibshirani1996regression] ) and the original problem becomes, $$\begin{aligned} \min_{\beta} ||k-x^{\top}\beta||_2+\alpha ||\beta||_1\label{lasso}\end{aligned}$$ $||\beta||_1 = \sum_i |\beta_i|$ denotes the $L1$ norm of $\beta$. The LASSO regression helps select the most critical features that are linearly related to the response. Second, K-fold cross-validation will be used to measure the performance of our model. We construct features on each day that are derived from the clustering results of daily profiles. Note that the k-means algorithms are applied on the $DH$ daily profiles. Thus, each household or user on each day will be assigned to a typical pattern (cluster). Features that are related to traffic congestion can be both aggregate or disaggregate. At an aggregate level, we assume that all households/users under the same typical pattern on each day affect the congestion in the same way (namely all households/users under the same pattern are homogeneous), and speculate that the total number of households/users under each of the typical patterns on each day attributes to congestion. At a disaggregated level, we assume each sampled household/user represents a particular group of users, and each contributes to congestion differently as opposed to the user homogeneity assumption. Therefore, we create features for each sample household/user for the predictor of traffic congestion. In the rest of the paper, we refer to the two types of features as “aggregate features” and “disaggregate features”, respectively. Aggregate features are highly compressed. They are a vector of $K-1$ elements for each daily profile. Each element is the ratio of households/users that are under a pattern on that day. The element of one last pattern can be dropped from the vector as a result of redundancy. Those aggregate features would offer effective prediction if the assumption holds that all households/users are homogeneous under the same electricity use pattern. If this is not reasonable, then disaggregate features allow us to examine household/user-

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avery began. He smiled habitually as a matter of business, and tried to be polite to everybody, even to the beggar to whom he refused a penny. He had the look of a weazel, and the mien of a man of letters. He had a strong resemblance to the portraits of the Abbé Delille. He affected drinking with waggoners. Nobody ever saw him drunk. He smoked a large pipe. He wore a smock, and under it an old black tuxedo coat. He made pretensions to literature and materialism. There were names which he often pronounced in support of anything whatever that he might say. Voltaire, Raynal, Parny, and, oddly enough, St. Augustine. He professed to have "a system." For the rest, a great swindler. A _filou-sophe. be_ There is such a variety. It will be remembered, that he pretended to have been in the service; he related with some pomp that at Waterloo, being sergeant in a Sixth or Ninth Light something, he alone, against a squadron of Hussars of Death, had covered with his body, and saved amid a shower of grapeshot, "a general dangerously wounded." Hence the flamboyant picture on his sign, and the name of his inn, which was spoken of in the region as the "tavern of the sergeant of Waterloo." He was liberal, classical, and a Bonapartist. He had contributed to the homeless shelter. It was said in the village that he had studied for the priesthood. We believebf that he had only studied in Holland to be an innkeeper. This mongrel cur was, according to all probability, some Fleming of Lille in Flanders, a Frenchman in Paris, a Belgian in Brussels, conveniently on the fence between the two frontiers. We are acquainted with his prowess at Waterloo. As we have seen, he exaggerated it a little. Ebb and flow, wandering, adventure, was his element; a violated conscience is followed by a loose life; and without doubt, at the stormy epoch of the 18th of June, 1815, Thénardier belonged to that species of marauding canteen owners of whom we have spoken, scouring the country, robbing here and selling there, and travelling in family style, man, woman, and children, in some rickety carry-all, in the wake of marching troops, with the instinct to attach himself always to the victorious army. This campaign over, having, as he said, some funds, he had opened an eatery at Montfermeil. These funds, composed of purses and watches, gold rings and silver crosses, gathered at the harvest time in the furrows sown with corpses, did not form a great total, and had not lasted this canteen owner, now become a tavern-keeper, very long. Thénardier had that indescribable stiffness of gesture which, with an oath, reminds you of the barracks, and, with a sign of the cross of the seminary. He was a fine talker. He was fond of being thought learned. Nevertheless, the schoolmaster remarked that he made mistakes in pronunciation. He made out travellers' bills in a superior style, but practised eyes sometimes found them faulty in orthography. Thénardier was sly, greedy, lounging, and clever. He did not disdain servant girls, consequently his wife had no more of them. This giantess was jealous. It seemed to her that this little, lean, and yellow man must be the object of universal desire. Thénardier, above all a man of astuteness and poise, was a rascal of the subdued order. This is the worst species; there is hypocrisy in it. Not that Thénardier was not on occasion capable of anger, quite as much as his wife; but that was very rare, and at such times, as if he were at war with the whole human race, as if he had in him a deep furnace of hatred, as if he were of those who are perpetually avenging themselves, who accuse everybody about them of the evils that befall them, and are always ready to throw on the first comer, as legitimate grievance, the sum-total of the deceptions, failures, and calamities of their life—as all this leaven worked in him, and boiled up into his mouth and eyes, he was frightful. Woe to him who came within reach of his fury, then! Besides all his other qualities, Thénardier was attentive and penetrating, silent or talkative as occasion required, and always with great intelligence. He had somewhat the look of sailors accustomed to squinting the eye in looking through spy-glasses. Thenardier was a statesman. Every new-comer who entered the tavern said, on seeing the Thénardiess: There is the master of the house. It was an error. She was not even the mistress. The husband was both master and mistress. She performed, he created. He directed everything by a sort of invisible and continuous magnetic action. A word sufficed, sometimes a sign; the mastodon obeyed. Thénardier was to her, without her being really aware of it, a sort of being apart and sovereign. She had the virtues of her order of creation; never would she have differed in any detail with "Monsieur Thénardier"—nor—impossible supposition—would she have publicly quarrelled with her husband, on any matter whatever. Never had she committed "before company" that fault of which women are so often guilty, and which is called in parliamentary language: discovering the crown. Although their accord had no other result than evil, there was food for contemplation in the submission of the Thénardiess to her husband. This bustling mountain of flesh moved under the little finger of this frail despot. It was, viewed from its dwarfed and grotesque side, this great universal fact: the homage of matter to spirit; for certain deformities have their origin in the depths even of eternal beauty. There was somewhat of the unknown in Thénardier; hence the absolute empire of this man over this woman. At times, she looked upon him as upon a lighted candle; at others, she felt him like a claw. This woman was a formidable creation, who loved nothing but her children, and feared nothing but her husband. She was a mother because she was a mammal. Her maternal feelings stopped with her girls, and, as we shall see, did not extend to boys. The man had but one thought—to get rich. He did not succeed. His great talents had no adequate opportunity. Thénardier at Montfermeil was ruining himself, if ruin is possible at zero. In Switzerland, or in the Pyrenees, this penniless rogue would have become a millionaire. But where fate places the innkeeper he must browse. It is understood that the word _innkeeper_ is employed here in a restricted sense, and does not extend to an entire class. In this same year, 1823, Thénardier owed about fifteen hundred francs, of pressing debts, which rendered him moody. However obstinately unjust destiny was to him, Thénardier was one of those men who best understood, to the greatest depth and in the most modem style, that which is a virtue among the barbarous, and an article of commerce among the civilised—hospitality. He was, besides, an admirable poacher, and was counted an excellent shot. He had a certain cool and quiet laugh, which was particularly dangerous.bg His theories of innkeeping sometimes sprang from him by flashes. He had certain professional aphorisms which he inculcated in the mind of his wife. "The duty of the innkeeper," said he to her one day, emphatically, and in a low voice, "is to sell to the first comer, food, rest, light, fire, dirty linen, servants, fleas, and smiles; to stop travellers, empty small purses, and honestly lighten large ones; to receive families who are travelling with respect: scrape the man, pluck the woman, and pick the child; to charge for the open window, the closed window, the chimney corner, the sofa, the chair, the stool, the bench, the feather bed, the mattress, and the straw bed; to know how much the mirror is worn, and to tax that; and, by the five hundred thousand devils, to make the traveller pay for everything, even to the flies that his dog eats!" This man and this woman were cunning and rage married—a hideous and terrible pair. While the husband calculated and schemed, the Thénardiess thought not of absent creditors, took no care either for yesterday or the morrow, and lived passionately in the present moment. Such were these two beings. Cosette was between them, undergoing their double pressure, like a creature who is at the same time being bruised by a millstone, and lacerated with pincers. The man and the woman had each a different way. Cosette was beaten unmercifully; that came from the woman. She went barefoot in winter; that came from the man. Cosette ran up stairs and down stairs; washed, brushed, scrubbed, swept, ran, slaved, got out of breath, lifted heavy things, and, puny as she was, did the rough work. No pity; a fer

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and her work.[16][17] Vanga incorrectly predicted that the 1994 World Cup soccer final would be played between "two teams beginning with B". Some say that she foretold it that way because of the penalty that Bulgaria wasn't given. One finalist was Brazil, but Bulgaria was eliminated by Italy in the semifinals.[18] Vanga predicted that a World War III will start in November 2010 and last until October 2014.[19][20] However, according to close friends, Vanga was not the type to voice predictions she saw if they were catastrophic because she knew that chaos that would ensue around those she told. Witnesses and close friends also claim that she never made such prophecies, and in fact when asked claimed that there will be no World War III.[17][21] Nevertheless, after North Korea — a nuclear nation — attacked South Korea on 23 November 2010,[22] there was a spike in internet interest about Vanga concerning this alleged prophecy.[23] Vanga attempted to prophesy about newborn or unborn children. She said that she was "seeing" and "talking" to people, who had died hundreds of years ago. Vanga talked about the future, although she did not like to. In her words, in 200 years man will make contact with brothers in mind from other worlds. She said that many aliens have been living on the earth for years. They came from the planet, which in their language is called Vamfim, and is the third planet from the Earth. Followers of Vanga believe that she predicted the precise date of her own death,[17] dreaming that she would die on 11 August, and be buried on 13 August. Shortly before that she had said that a ten-year-old blind girl living in France was to inherit her gift, and that people would soon hear about her.[citation needed] Apart from prophesying, Vanga was believed to be a healer, but only through herbal medicines. According to her, people had to heal themselves only with herbs from the country they live in. She prescribed washing with an infusion of herbs and spices, claiming some beneficial effect on the skin. Vanga did not oppose mainstream medicine, although she thought that taking too much medicines is bad, because "they close the doors, through which nature restores the balance in the body with herbs."[citation needed]. Accounts on the predictions of Vanga are often controversial and distorted by the media. One recent attempt to systematically summarize the existing knowledge about Vanga was made in the documentary "Vanga. The visible and invisible world".[16][24] The movie includes interviews with some of the people who met Vanga in person, including Sergey Medvedev (press secretary to President of RussiaBoris Yeltsin in 1995–96; Sergey Medvedev visited Vanga as Yeltsin's envoy following Vanga's request to meet her), Neshka Robeva (Bulgarian rhythmic gymnast and coach), Sergey Mikhalkov (Soviet and Russian writer, author of the Soviet Union anthem), Nevena Tosheva (director of the first documentary about Vanga), Kirsan Ilyumzhinov (Kalmyk multi-millionaire businessman and politician). According to the documentary, Baba Vanga predicted Yeltsin's second electoral victory in 1995, and warned him about his heart condition. Several researchers have studied the phenomenon of Vanga in the attempt to establish whether she has any extraordinary capabilities. One of the first studies was initiated by the Bulgarian government and is described in the 1977 movie Fenomen[25] directed by Nevena Tosheva. Prominent Bulgarian psychiatrists Nicola Shipkovensky and Georgi Lozanov also studied the capabilities of Vanga. Reportedly, some of the studies concluded that about 80% of predictions of Vanga turned out to be accurate.[26] Vanga was widely known to be close to the government of Todor Zhivkov and, on several occasions, she appeared on public TV with him and other high officials of the Bulgarian Communist Party. The daughter of Todor Zhivkov befriended Baba Vanga in the late 60s or early 70s and she was protected by the communist state thereafter, which apparently used the situation to its own advantage, with or without knowledge of Baba Vanga. It has been alleged that Vanga used data gathered by the secret services to win the trust of her visitors, who came to her by state-orchestrated appointments made well in advance. Baba Vanga was very popular and the Bulgarian state decided to organize her services and charge for them, giving Baba Vanga a state salary which was a tiny fraction of the earnings. Lists of people who were coming to see Vanga were formed by appointment, organized by the state, from the early 70s; as her fame rose, many foreign and domestic politicians were also visiting Vanga, and the house in which she worked was reportedly bugged. Members of the secret service worked in her environment, and she may have been manipulated to give suggestions to visiting politicians.[16] Vanga is well known in the Russian-speaking world. Some Russian nationalists[who?] consider her a true prophet of God[citation needed] and use her alleged prophecies of an upcoming nuclear war and Russian victory to argue for more robust defense policy and, more generally, for a more optimistic view of Russia's future.[citation needed] On the other hand, many Christians[who?] reject her as a spiritist and a false prophet who acted on behalf of the Devil. Thus there is a widely propagated story of Vanga becoming enraged at a visiting cleric (Nathanael, metropolitan of Nevrokop) carrying a holy relic, saying that this presence prevented her from prophesying.[citation needed] ^According to Encyclopædia Britannica Eleventh Edition, at the beginning of the 20th century the Bulgarians constituted the majority of the population in the whole region of Macedonia. They are described in the encyclopaedia as "Slavs, the bulk of which is regarded by almost all independent sources as Bulgarians": 1,150,000, whereof, 1,000,000 Orthodox and 150,000 Muslims (the so-called Pomaks); Turks: ca. 500,000 (Muslims); Greeks: ca. 250,000, whereof ca. 240,000 Orthodox and 14,000 Muslims; Albanians: ca. 120,000, whereof 10,000 Orthodox and 110,000 Muslims; Vlachs: ca. 90,000 Orthodox and 3,000 Muslims; Jews: ca. 75,000; Roma: ca. 50,000, whereof 35,000 Orthodox and 15,000 Muslims; In total 1,300,000 Christians (almost exclusively Orthodox), 800,000 Muslims, 75,000 Jews, a total population of ca. 2,200,000 for the whole of Macedonia.use std::fs::File; use std::io::Read; use std::marker::PhantomData; use std::mem; use std::path::Path; use std::str; use crate::context::{Context, GLintptr, Program, Shader, UniformLocation}; use crate::resource::{GLPrimitive, GPUVec}; #[path = "../error.rs"] mod error; /// Structure encapsulating a program. pub struct Effect { program: Program, vshader: Shader, fshader: Shader, } impl Effect { /// Creates a new shader program from two files containing the vertex and fragment shader. pub fn new(vshader_path: &Path, fshader_path: &Path) -> Option<Effect> { let mut vshader = String::new(); let mut fshader = String::new(); if File::open(vshader_path) .map(|mut v| v.read_to_string(&mut vshader)) .is_err() { return None; } if File::open(fshader_path) .map(|mut f| f.read_to_string(&mut fshader)) .is_err() { return None; } Some(Effect::new_from_str(&vshader[..], &fshader[..])) } /// Creates a new shader program from strings of the vertex and fragment shader. pub fn new_from_str(vshader: &str, fshader: &str) -> Effect { let (program, vshader, fshader) = load_shader_program(vshader, fshader); Effect { program, vshader, fshader, } } /// Gets a uniform variable from the shader program. pub fn get_uniform<T: GLPrimitive>(&self, name: &str) -> Option<ShaderUniform<T>> { let ctxt = Context::get(); let location = ctxt.get_uniform_location(&self.program, name); if ctxt.get_error() == 0 { if let Some(id) = location { let data_type = PhantomData; return Some(ShaderUniform { id, data_type }); } } return None; } /// Gets an attribute from

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g: local modifications to the charm not the layer) <aisrael_> oh, it has a layers.yaml <lazypower> --force will allow you to override that and get past it, but its erring on the side of caution for you <lazypower> i'm referring to the constructed charm <lazypower> the artifact <aisrael_> lazypower: removing that fixed it. Should I open a bug? * lazypower is doing a terrible job of explaining htis <lazypower> nah its intended behavior <lazypower> if you run with -l DEBUG <lazypower> it tells you what its matching on i think <aisrael_> lazypower: Right, the previous build left the layers.yaml in $JUJU_REPOSITORY/trusty/mycharm. Bad artifact. <lazypower> :) <aisrael_> lazypower: so a build copies over the charm, rather than replacing or rsyncing, right? <lazypower> the one thing build doesn't do, is take care of removal <lazypower> say you remove an interface from layer.yaml, then re-run build - you need to implicitly rm -rf the built charm and then build, otherwise that interface will linger <lazypower> aisrael_ correct, there are different strategies at play <aisrael_> lazypower: ack. I can see an argument for doing that cleanup automatically, even if it's an extra flag <lazypower> like config.yaml, metadata.yaml get merged <lazypower> other files have a default policy of highest layer that has this file wins. <aisrael_> i.e, if I'm writing a charm in layers/, I'd expect that to be authoritative <lazypower> so whatever your top layer is, will override files below it, save for a handfull of special files. and your local layer takes precedence over the interfaces.juju.solutions api yes but only if you have LAYER_PATH set <lazypower> same with INTERFACE_PATH <aisrael_> like the charm equivalent to make clean <lazypower> yeah <aisrael_> Caffeinated ramblings. Thanks for the help unblocking me! <lazypower> seems like charm build --clean should just nuke the compiled dir if exists then build. <lazypower> NP thanks for the questions :) <Icey> how hard would it be to change the AMIs used by Juju to be something that's EBS optimized? <aisrael_> lazypower: I am now a layer convert (not that I wasn't a fan before). <lazypower> :) <aisrael_> well, layer + reactive <lazypower> Layer + reactive is a powerful tool <lazypower> aisrael_ : https://github.com/mbruzek/layer-k8s/pull/5 <aisrael_> Niiiiice <lazypower> working on a feature branch with matt for the last 2 days, working independently there have been zero merge conflicts - putting complexity in its place :) <lazypower> and the change sets are getting smaller <aisrael_> lazypower: lxc now builds for os x, so if we can run lxd in a container... we might be closer to having a working local provider. <lazypower> nice! <aisrael_> I'll poke around at it tonight when I'm back home. <marcoceppi> lazypower: +1 to a --clean flag where it removes the previous build <marcoceppi> helpful when heavily devving <lazypower> I'll feature rq it <lazypower> https://github.com/juju/charm-tools/issues/33 <cholcombe> can you combine all your juju actions code into one file and symlink it just like the hooks? <marcoceppi> cholcombe: yes <cholcombe> marcoceppi, nice :) <cholcombe> so i do the usual @hooks.hook business <marcoceppi> cholcombe: welllll <marcoceppi> cholcombe: no one has tried that, they're not hooks, they're actions, so it's hard to say if that code will respect that <marcoceppi> cholcombe: for now it's probably better to just make a python module and then stub the import/execute of that module/methods in each file <cholcombe> marcoceppi, if i remember right at the code i looked at it just calls the hook with the matching filename that it was called with <marcoceppi> cholcombe: sure, but actions are not in the hooks directory <cholcombe> oh i know <marcoceppi> so if there's any attempt to parse out hook related file paths <marcoceppi> it'll fail <cholcombe> hmm yeah * cholcombe goes back to splitting them up #juju 2015-10-29 <vila> mgz_: ping <vila_> mgz_: ping <sharan> Hi <sharan> If i have deployed for example abc/0,abc/1,abc/2,abc/3 and abc/4 <sharan> in relation-changed hook is it possible for me to get abc/4 unit directly instead of using relation-list <vila_> mgz_: ping :-} <sharan> Hi i have abc/0,abc/1,abc/2,abc/3 and abc/4 units, Is it possible for me to get the highest number unit in this case like abc/4 in relation-changed hook directly without using relation-list <sharan> Hi i have abc/0,abc/1,abc/2,abc/3 and abc/4 units, Is it possible for me to get the highest number unit in this case like abc/4 in relation-changed hook directly without using relation-list <vila_> mgz_: Ping <cory_fu> jose: Hey, you have ethercalc locked on the RQ. Are you currently looking at that, or should I take a look? <aatchison> Hello. I am having difficulties while bootstrapping JuJu. After node aquisition and deployment on our MaaS cluster, I get this error: Attempt 1 to download tools from https://streams.canonical.com/juju/tools/releases/juju-1.24.7-trusty-amd64.tgz... <aatchison> curl: (7) Failed to connect to streams.canonical.com port 443: Connection timed out <aatchison> tools from https://streams.canonical.com/juju/tools/releases/juju-1.24.7-trusty-amd64.tgz downloaded: HTTP 000; time 126.855s; size 0 bytes; speed 0.000 bytes/s Download failed..... wait 15s <aatchison> I can curl to that address and get the file, any ideas? <aatchison> I am using ppa:juju/stable and ppa:maas/stable on 14.04. <aatchison> Sorry, I timed out. I donât know if anyone responded or not :/ <pmatulis> nope <alexisb> aatchison, if you are still around, could this potentially be your issue: http://askubuntu.com/questions/465508/juju-bootstrap-debug-failed-to-connect-https-streams-canonical-com <aatchison> ahh, thank you <aatchison> checking that out <moqq> anyone have any idea what i should do if one of the jujud agents out of nowhere refuses to start up with this error: âpanic: runtime error: invalid memory address or nil pointer dereferenceâ <moqq> full logs: http://paste.ubuntu.com/13002509/ <moqq> was thinking it might be related to https://bugs.launchpad.net/juju-core/+bug/1496188 but iâm not really sure <mup> Bug #1496188: panic in juju worker <panic> <juju-core:Triaged> <https://launchpad.net/bugs/1496188> <moqq> if i have an agent with message âmessage: agent is not communicating with the server" <moqq> i just want to delete that unit <moqq> but remove-unit does nothing <moqq> (WHY?!?!) #juju 2015-10-30 <gennadiy> hi all, i have question about removing aws security groups: seems juju doesn't remove security group when machine is removed. am i right? and today i have got exception: security groups number limit is reached <gennadiy> do we need to remove security group manually? do you have some specific config field to reuse security groups

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731(2), 362 S.E.2d 768. Appellant, after being duly notified of both the calendar *217 call and the court call voluntarily elected not to take action either to obtain his timely presence in court or to provide for an authorized representative to appear on his behalf at these proceedings. The bench trial was held on August 8, 1996. Appellant received a copy of appellees' motion for bench trial and to strike his defensive pleadings on August 6, 1996; however, he did not file his objections until August 12, 1996, after the bench trial was held. Neither did appellant inform the court of any difficulties nor communicate to the court in any manner, regarding the calendar call or subsequent call of the case to trial. By this repetitive conduct, which ultimately resulted in the striking of his entire defensive pleadings, appellant implicitly waived his right to trial by jury. Compare Goss, supra; see also Robertson v. Central Mut. Ins. Co., 165 Ga.App. 167, 299 S.E.2d 894; Galanti v. Emerald City Records, 144 Ga.App. 773, 774(2), 242 S.E.2d 368. This holding is consistent with the well-established appellate rule that on appeal a party cannot complain of a judgment or ruling of the trial court which his own conduct or legal strategy aided in causing. Williams v. Food Lion, 213 Ga.App. 865, 868, 446 S.E.2d 221. Green v. Snellings, 260 Ga. 751, 400 S.E.2d 2 is distinguishable; although incarcerated, appellant had ample notice of both the calendar call and the court call, and he also had prior notice of appellees' motions to dismiss appellant's defensive pleadings and for bench trial. Appellant already had filed a demand for a jury trial; he did not need express notice of the bench trial to safeguard his opportunity to make such demand. The case at bar, unlike Green, supra, involves the issue of waiver of an existing demand for trial by jury. In view of this holding, we need not address the issue of harmless error. Compare Newman v. Greer, 131 Ga.App. 128, 131-132, 205 S.E.2d 486. Judgment affirmed. ELDRIDGE, J., and HAROLD R. BANKE, Senior Appellate Judge, concur. President Trump said Thursday that he is considering 15 candidates to replace John Bolton as national security adviser, the day after he told reporters that there were only five contenders for the position. Mr. Trump will announce his pick sometime next week, he said Wednesday. "A lot of people want the job. It's a great job. It's a lot of fun to work with Donald Trump. It's easy because I make all the decisions," Mr. Trump said of the 15 people he said were under consideration. On Wednesday, Mr. Trump had said, "I have five people that want it very much." He called the candidates "good people I've gotten to know" during his tenure. The president added that he would "be announcing somebody next week." Get Breaking News Delivered to Your Inbox Mr. Trump announced over Twitter Tuesday that he had "informed John Bolton" that "his services are no longer needed" and that he had asked for Bolton's resignation. Mr. Trump reiterated that he had disagreed with Bolton on several issues, including Bolton's desire to take the "Libyan model" to North Korea. In 2018, Bolton said on "Face the Nation" that he was "looking at the Libya model of 2003, 2004" as a model for a nuclear deal with North Korea. In 2003, Libya had negotiated sanctions relief from the United States in exchange for renouncing its nascent nuclear program. Eight years later, Libyan leader Muammar Gaddafi was overthrown in a gruesome killing by Western-backed rebels. Mr. Trump considered this remark a "very big" mistake. "You just take a look at what happened with Gaddafi. That was not a good statement to make," he said. "And it set us back." President Trump has had three national security advisers so far: Michael Flynn, H.R. McMaster and Bolton. Kathryn Watson contributed to this report.(CNN) The nation's 38 million food stamp recipients will get their February benefits early amid the partial government shutdown. State officials say their allotments will be loaded onto electronic benefit transfer cards by Sunday, rather than next month. That's the only way the federal government can make the payment since the program initially wasn't funded beyond January. The US Department of Agriculture announced last week that it is using a provision allowing it to make obligated payments within 30 days of a government funding lapse. The shutdown began after funding ran out December 21. The change has left states racing to issue the February benefits -- which are expected to total $4.8 billion -- by January 20. Typically, states issue benefits over the course of a month, in part to make sure grocery stores have enough food and to provide them with a steady stream of customers. Households receive $245 a month, on average. State officials are working closely with the federal agency to speed up payments, and all are expected to be able to comply, said Ann Flagg, director of the Collaborative Centers for Policy & Practice at the American Public Human Services Association, which represents state and local health and human service agencies. Read MoreShowing 1 to 6 of 6 Quiz 2 The following are sources of information on laws or regulations concerning biotechnologyrelated activated or products. Spell out the meaning of each. Circle the site where you can actually comment on proposed laws. USC: United States Code eCFR: ele BTEC 3317 - Homework 1 Put your name and student number on the first line of all assignments The second line will be a relevant title for your homework Then your answers begin on the 3rd line. Go to: http:/www.accessdata.fda.gov/scripts/fcn/fcnNavigation. BTEC3317W Homework6 Orphan Drugs for Rare Diseases There will be no group presentation for next week. 1. Go to: http:/www.fda.gov/ForIndustry/DevelopingProductsforRareDiseasesConditions/Howtoapplyf orOrphanProductDesignation/ucm364750.htm a. Give a brief Biotechnology Regulatory Environment Flashcards Showing 1 to 1 of 1 What is the daily official publication of the US government where all newly proposed and final federal rulemaking (including regulations) can be accessed, and where the public can comment on proposed laws?TNW Sites Twitter advertisers can now target ads based on the apps a user has installed After an announcement that it would begin tracking users’ app installs almost two weeks ago, Twitter has begun to allow advertisers to use that data to target users more directly and reach the most valuable audiences. The functionality is a little more in depth than originally anticipated, however. For example, in addition to app installs, marketers can look at which apps a user has registered or made purchases within. This could allow them to continually remind forgetful users to sign up, or persuade them into buying into a special promotion. Twitter says it has already begun testing this functionality with some brands and has received positive feedback on its usefulness. Still, many users won’t be happy about companies knowing what they’re doing with their apps , so they can disable the ‘feature’ by unchecking the box for ad tailoring in the Twitter app’s privacy settings. The company also says it respects the “limit ad tracking” setting on iOS and the “opt out of interest based advertising” option on Android.Q: Environ's body doesn't allow for making an \item As part of a document process/workflow, it's easier to work with environments. However, in some cases the environment contents needs specific formatting. As such, it's convenient to use the environ package to capture the environment \BODY, and then use it as needed. The following elementary implementation doesn't work though: \documentclass{article} \usepackage{environ} \NewEnviron{HEADING}{% \item[\BODY] } \begin{document} \begin{description} \begin{HEADING} Heading \end{HEADING} \end{description} \end{document} How can I get around to having environment HEADING process it's \BODY as an argument in the expected way? A: You have to execute \item[...] outside the environment, because it must be at the outer level in a list. The reason is that \item does \@item, which sets \everypar; having it in a group would cause every sort of problems. \documentclass{article} \usepackage{environ} \NewEnviron{HEADING}{% \expandafter\gdef\expandafter\THISHEADING\expandafter{% \expandafter\item\expandafter[\BODY]% }% \aftergroup\THISHEADING } \begin{document} \begin{description} \begin{HEADING} Heading \end{HEADING} Something to follow \end{description} \end{document} The authors confirm that, for approved reasons, some access restrictions apply to the data underlying the findings

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end did not work. 747 N.W.2d 276 (2008) PEOPLE of the State of Michigan, Plaintiff-Appellee, v. Lewis HARRIS, Defendant-Appellant. Docket No. 135630. COA No. 271929. Supreme Court of Michigan. April 28, 2008. On order of the Court, the application for leave to appeal the December 20, 2007 judgment of the Court of Appeals is considered, and it is DENIED, because we are not persuaded that the questions presented should be reviewed by this Court. Former 'Apprentice' contestant battles Trump in defamation lawsuit hearing Kevin McCoy | USA TODAY Show Caption Hide Caption Attorney: President is not above the law A former cast member of the reality TV show 'The Apprentice' who has accused Donald Trump of unwanted sexual contact and has filed a New York defamation lawsuit against him has thanked her lawyers and says the case should go forward. (Dec. 5) NEW YORK — The lawsuit filed against President Trump by a former contestant on The Apprentice who accused him of groping and then defaming her moved a step closer Tuesday to a decision on whether the case should go to trial. In clashing court arguments, lawyers for Summer Zervos said she suffered threats after Trump publicly said she had "made up" her claims in a politically motivated effort to help Hillary Clinton beat him in the 2016 presidential race. Trump "cannot be allowed to attack a woman who has factually described his sexual groping and be allowed to get off scot-free," argued Zervos attorney Mariann Meier Wang during the hour-long hearing before Manhattan Supreme Court Justice Jennifer Schecter. Marc Kasowitz, Trump's personal lawyer, contended that Trump said nothing wrong while defending himself. He also argued that the case cannot legally be tried in state court, and should be dismissed or at least delayed. Citing the U.S. Constitution's supremacy clause, he said Trump's motion to throw out the case "has nothing to do with putting anyone above the law." Instead, he said it was about "protecting the ability of the president to do his constitutionally-mandated job." Schecter did not issue an immediate ruling on the dismissal motion, saying she would study the court arguments and legal briefs before making a decision in the potentially precedent-setting case. Zervos, who sat quietly in the lower Manhattan courtroom behind her attorneys, is among roughly a dozen women who publicly accused Trump of sexual misconduct during last year's presidential race. But she's the first to sue him. Filed in January, her legal action alleges that Trump “ambushed” her more than once in 2007, six years before he was elected president, by kissing her on the mouth, touching her breast, and pressing his genitals against her. Zervos also accused Trump of defaming her during campaign rallies and via Twitter, his favorite social media platform. At an Oct. 15, 2016, campaign stop in Maine, Trump alluded to Zervos by referring to "false allegations and outright lies, in an effort to elect Hillary Clinton President," the lawsuit charges. Woman who accused Trump of groping her files lawsuit Summer Zervos accused Donald Trump of groping her, and she filed a defamation lawsuit after he called her accusations a lie. Video provided by Newsy Trump has denied Zervos' allegations, which echo other women’s claims. Trump has dismissed them as false. During Tuesday's court hearing, Kasowitz contended that Trump's statements about Zervos were constitutionally protected remarks in which he defended himself. Trump's attorneys are relying on some of the legal arguments then-President Bill Clinton's lawyers made when he was accused in a 1994 federal court lawsuit over an alleged sexual assault. Paula Jones alleged that the attack took place in 1991 when she was an Arkansas state employee and Clinton was the state's governor. More: Trump borrows Bill Clinton's legal strategy as he battles defamation lawsuit The U.S. Supreme Court allowed that case to proceed in federal court. After a four-year legal battle, Clinton agreed to pay an $850,000 settlement. Both sides in the Zervos case said there has been no definitive ruling whether a sitting U.S. president may be sued in a state court over allegations that do not involve official White House duties. Kasowitz cited a footnote in the Supreme Court's Clinton-Jones decision to support his argument that the Zervos case must be dismissed or postponed until Trump's presidential term has ended. The footnote stated that “any direct control by a state court over the president ... may implicate concerns that are quite different” from the issues in the Jones case. When Schecter asked whether he believed that she would be unable to preside over the lawsuit, Kasowitz responded, "not with respect to the President, your honor." Schecter noted that the footnote "leaves the question open," without deciding the issue. "What better court to hear a defamation case against a born and bred New Yorker," who some of the allegedly improper statements just a few miles from the courthouse, argued Wang. Wang added that Zervos' legal team would accommodate Trump by scheduling sworn depositions from him around his White House schedule — or even holding them in between presidential golf outings at his Mar-a-Lago Florida estate. Kasowitz declined to comment after the hearing. Zervos said little publicly other than thanking her attorneys. As she made their way through a crowd of TV and still photographers, co-counsel Gloria Allred said Zervos had shown "admirable courage" in challenging Trump. Follow USA TODAY reporter Kevin McCoy on Twitter: @kmccoynycThe “mega trend” that swallowed Silicon Valley FORTUNE — It’s 8 a.m. on a Thursday, and a message pops up on Nancy Tcheou’s iPhone. It shows a map of downtown San Francisco with the exact location of a guy she’s never met named Zach Lagod. Her red Honda Civic is easy to spot with a furry pink mustache covering the bumper. She pulls up, greets Lagod by name, and the two do a fist-bump “hello.” Lagod jumps in the front seat, and they’re off to the train station 15 minutes away. The two make small talk, as Lagod flips through songs on the radio. Tcheou is not Lagod’s friend, and she is not a professional taxi driver. She’s an unemployed 25-year-old who happens to have time on her hands and a car filled with gas. So she signed up to give strangers a ride in her car using a new mobile ridesharing service called Lyft. It’s one of a flood of new startups that aim to create online and mobile social networks that let people share in the real world. There are apps that find and borrow power tools from your neighbors, that let you rent a nearby stranger’s car or hire someone close by to pick up dog food. You can go online to rent your parking spot when you’re not using it or you can find a home for your dog when you travel. Call it the new share economy or as its known in the industry: the collaborative consumption movement. Airbnb led the way. The site, which lets people rent their homes to travelers, has booked more than 10 million nights in 192 countries since its start in 1998, and last year it generated an estimated $58 million. Now people are taking a look at any under-used assets they may have, whether it’s an empty seat in their car and time on their hands, or a bike sitting in the garage, a vacant parking space in their driveway, an empty cubicle at their office or a power saw seldom used. And they’re sharing, borrowing or renting them. “People are looking around and saying, ‘Hey, I can rent out my car. I can share my skills. I don’t need to own a designer dress, I can rent one,’” says Rachel Botsman, author of What’s Mine is Yours: The Rise of Collaborative Consumption. “There is a big shift underway from the ‘me’ of hyper-consumption to the ‘we’ culture of collaborative consumption.” The Internet and mobile technology are driving that shift. Some 78% of people say they’re far more inclined to share with strangers in the offline world because of social networking. Smart phones add a new layer, giving you instant access and location data about who is nearby. Add in people’s environmental consciousness and thriftiness in the economic recession, and demand grows even more. Security remains a big issue for many of these peer-to-peer startups following disaster stories of people whose homes got trashed after using Airbnb. At Lyft, drivers must be 23 or older, have a driver’s license for more than three years and pass background check and DMV record checks, says Lyft’s co-founder John Zimmer. People’s cars must be clean, newer and checked for safety, and both drivers and passengers must have credit cards, Facebook FB accounts and GPS capabilities on their phone for security. Ratings are key too. If your average rating is low, then your account is closed. Zimmer says he worked for more than three months to develop an insurance policy that gives drivers $1 million in extra liability while they’re driving. “It is this real peace of mind for our users,” he says. The strategy is working: Zimmer’s other startup, Z

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+ n = -2*h + 61. Solve u - h = -b*u for u. 4 Suppose 25*s - 76 = 199. Solve 12 = -s*x - 21 for x. -3 Let w = 11 + -8. Let a = 13 - w. Suppose -a = -v - 4*v. Solve 5*s = v*s for s. 0 Let t(f) be the second derivative of -f**3/6 - 2*f**2 + f. Let u be t(-10). Let z = u + -6. Solve 5*l + 2 + 3 = z for l. -1 Let h = -25 + 29. Suppose -5*l - b + 3 = -1, 3*b - 12 = -h*l. Solve t = -3 - l for t. -3 Let v(y) = -9*y + 35. Let t be v(4). Let i be ((-1)/t)/(4 + 102/(-26)). Solve -3*c - 4 + i = 0 for c. 3 Let b be ((0/3)/(-1))/(-2). Suppose -2*d + 7 = 5*j, b = -5*j + 5*d + 45 - 10. Solve -2*i - j*i + 5 = 0 for i. 1 Let p be -1*(72/(-20))/((-6)/(-15)). Let w = -8 + 14. Let k(b) = b**3 + 5*b**2 + 2*b - 3. Let i be k(-4). Solve -p - w = -i*q for q. 3 Let y(j) = j**3 + 8*j**2 - j - 6. Let q be y(-8). Let d be (0 - (q + 0))/((-4)/4). Solve 0 = d*x - 6*x - 16 for x. -4 Let x = 571 - 564. Solve 8*z + x = -33 for z. -5 Let w = -74 + 127. Let v = w + -48. Let k(a) = -11*a**3 - a**2 - a - 1. Let h be k(-1). Solve h + v = -5*c for c. -3 Let g = 1599 + -1594. Solve -8*o + 26 = g*o for o. 2 Suppose -4*t + 24 = 2*q + 2*q, 45 = 4*q - 3*t. Suppose 4*j + 5 - q = 0. Let x = -5 + 8. Solve x*r + 5 + j = 0 for r. -2 Let y(j) = j**3 - 4*j**2 - 4*j - 5. Let r be y(5). Suppose 0 = -3*m + 5*h + 44, -h - 4*h + 12 = 4*m. Solve i - 3*i + m = r for i. 4 Suppose 4*b - 2*b - 18 = 0. Let i(g) = g - 9. Let x be i(b). Let t be (-3 + -1)*(-22)/44. Solve x = 5*n - 3 - t for n. 1 Suppose -13*v + 70 = -229. Let s = v - 20. Solve 8*n - s*n = 15 for n. 3 Let l(x) = -x**3 + 13*x**2 + 16*x - 24. Let r be l(14). Solve 0 = -3*t + 2*t + r for t. 4 Suppose 0 = 3*u + 4*w - 23, 5*u - 47*w - 85 = -42*w. Solve u*b = 15*b for b. 0 Suppose 0 = 4*h - 2*h - 6. Suppose 0 = -h*b + 5*b - 36. Suppose 5*r = 5*n + 50, 5*r + 4 = -4*n + b. Solve r*p + 3 = 3*p for p. -1 Let y(w) = -w - 3. Let v be 14 + (3 - -1 - 4). Let l be y(v). Let q = 24 + l. Solve q + 2 = -3*p for p. -3 Suppose -5*u + 4*w = -0*w - 25, 20 = 4*u - 5*w. Solve u + 25 = 6*z for z. 5 Let h(g) be the second derivative of -g**5/10 + 25*g**4/6 - g**3/6 + 13*g**2 + 43*g. Let k be h(25). Solve 5*s - k = 6*s for s. -1 Suppose 0 = -4*g - 8*o + 3*o - 6, -g = -2*o - 5. Suppose g = -f - 6. Let z(k) = -k**2 - 10*k - 9. Let u be z(f). Solve u = 3*t - 3 for t. 5 Let f(a) = -a - 1. Let h(c) = 15. Let g(y) = 4*f(y) - h(y). Let s be g(-6). Solve 0 = -s*z + z for z. 0 Let u(o) be the third derivative of o**4/12 - 6*o**3 - 4*o**2. Let f be u(19). Solve -2*n = f*n + 8 for n. -2 Let d(u) = u**2 - 10*u - 9. Let w be d(7). Let s be (w/9)/(1/9). Let j be (12/s)/((-1)/5). Solve j*f - 4*f = 0 for f. 0 Let l = 483 - 444. Solve -26*a + 13*a = l for a. -3 Let l(z) = -2*z**2 - 13*z + 34. Let i(r) = 3*r**2 + 27*r - 67. Let p(n) = -3*i(n) - 5*l(n). Let j be p(14). Solve 0 = -4*x + j*x + 3 for x. 3 Suppose -4*q + 50 = q + x, -x = -2*q + 20. Let w(f) = -f**2 + 4*f + 1. Let o be w(3). Let p be (q/o)/((-7)/(-14)). Solve p*v = 2 - 7 for v. -1 Let s = -25 - -25. Suppose -p + 2*p = s. Solve 3 = -j - p*j for j. -3 Let t(m) = m**2 - 57*m - 645. Let j be t(-10). Solve 19 = -2*u + j for u. 3 Let q = 658 - 658. Solve q = 3*w - 2 - 10 for w. 4 Let b be (-134)/2144 - (-386)/32. Solve 6*r - 12 = b*r for r. -2 Suppose -7*o + 8*o - 2 = 0. Let b be (-2)/(-4)*o*2. Solve 2 = -b*l - 2 for l. -2 Let n be (-738)/(-36) - 1/2. Solve -69*s + 73*s - n = 0 for s. 5 Let m(a) = -a**3 + 4*a**2 + 4*a - 6. Let c(k) = -k**2 + 4*k + 9. Let j be c(5). Let d be m(j). Solve -d = 3*f - 1 for f. -3 Let k(m) = -50*m - 830. Let y be k(-19). Solve -125*g + y*g = 5 for g. -1 Let j be 4/(-6) + 1184/(-24). Let p = j + 75. Let z = -23 + p. Solve 1 = -x + z for x. 1 Let d = -417 - -421. Solve -20 = d*a - 8*a for a. 5 Let s be 1/4*1/(-2)*-16. Suppose -s*u + 4*u - 6 = 2*j, 2*j = u - 6. Solve 5*x - 3*x + 10 = u for x. -5 Let t be (-2 + -1)*(-2)/3. Suppose -t*c = -5*c. Let u(g) = 7*g**2. Let r be u(-1). Solve 2*o - r*o - 25 = c for o. -5 Suppose 8*l + 12*l = 880. Solve 3*u = -l + 32 for u. -4 Let v(z) =

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After applying the code, the price now reflects the discount. Quite a savings for just a few clicks huh? That shows just how easy it is to find and use an HP coupon code. Hope this helps. Now go save some money.[A case of adenosquamous gastric carcinoma successfully treated with TS-1, low-dose CDDP and docetaxel as neoadjuvant chemotherapy]. The patient was a 66-year-old male with extremely advanced gastric cancer type 3 and diagnosed with adenocarcinoma by endoscopic biopsies specimens. Combined chemotherapy of TS-1, CDDP and docetaxel was prescribed in order for tumor reduction and downstaging. TS-1 (80 mg/m(2)) was administered 28 days followed by 14 days rest as one course. CDDP (8 mg/m(2)) was administered on days 1, 2, 14 and 15 and docetaxel (40 mg/m(2)) was administered on day 1 and 14, followed by 4 weeks rest as one course. After 2 courses of treatment, a CT scan revealed a minor response of tumor reduction. Therefore, total gastrectomy, partial pancreas body and tail resection, and D 2 lymph node dissection were performed. The patient had undergone adjuvant chemotherapy of TS-1 and biweekly docetaxel after surgery with no recurrence for 13 months. Adverse reactions were grade 3 neutropenia and grade 2 diarrhea. Combined chemotherapy of TS-1, low-dose CDDP and docetaxel were intensive and required constant patient monitoring. However, it proved effective and feasible as a neoadjuvant chemotherapy regimen for advanced gastric cancer.Adaptive filtering and random variables coefficient for analyzing functional magnetic resonance imaging data. Functional magnetic resonance imaging (fMRI) is used to study brain functional connectivity (FC) after filtering the physiological noise (PN). Herein, we employ: adaptive filtering for removing nonstationary PN; random variables (RV) coefficient for FC analysis. Comparisons with standard techniques were performed by quantifying PN filtering and FC in neural vs. non-neural regions. As a result, adaptive filtering plus RV coefficient showed a greater suppression of PN and higher connectivity in neural regions, representing a novel effective approach to analyze fMRI data.Cheap NFL Jerseys China of Lot 636 Topoo Backdam Police are reportedly closing in on the killers of security guard/ businessman Gowchand Budhu, who was shot dead last Saturday at his Topoo, Corentyne home.Budhu, 58, of Lot 636 Topoo Backdam,2018 Nike Air Max 97, Albion, Corentyne, Berbice was allegedly slain at around 20:20 hrs,Cheap Jerseys From China, by two bandits who had invaded his home.His wife Parbattie Budhu,Atlanta Hawks Jerseys, 54, was badly beaten and treated at the Anamayah Memorial Hospital before being sent home.After the incident, investigators arrested one man from the area and kept him in custody. However, after intense investigation, he was released on station bail.Meanwhile,Cheap Wholesale Jerseys, police are following a number of leads and appear confident that they are making inroads in the investigation. Arrests are expected soon.A post mortem examination by Pathologist Dr. Vivikanand Brijmohan at the Port Mourant Hospital concluded that Budhu died from shock and haemorrhage due to gunshot injuries.Budhu operates a chicken farm at his home while also working as a security guard at the Albion Front Primary School. The family also operates a grocery shop and a beer garden in an adjoining building in the lower flat at the front of yard. That business is operated by the wife.Injured: Parbattie BudhuDead: Gowchand BudhuThe victim’s wife has said she had taken a bath and was about to enter the lower flat when two masked and armed bandits confronted her.The bandits were allegedly clad in their briefs only with the bodies covered in mud and were wearing coloured toque masks.She said one of the intruders gun-butted and punched her, while ordering her to be quiet.Gowchand, who had retired to bed, reportedly heard the commotion and his wife’s cries and hurried downstairs.The husband, a licensed firearm holder, reportedly raced back upstairs and grabbed his 12 gauge shot gun. He was reportedly heading back to the lower flat when he was shot a number of times by one of the bandits who had mounted the inner stairs.After shooting Gowchand, the bandits reportedly fled the scene empty handed.The woman had told investigators that she did not know how she reached upstairs,Wholesale NFL Jerseys, and after regaining consciousness,Cheap NFL Jerseys, found herself lying in the living room next to her husband.The man’s shotgun with two cartridges was found next to his body.The police also recovered a number of 12 gauge cartridges, a revolver and a number of rounds.View full sizeEverton Bailey Jr./The OregonianLake Oswego Councilor Bill Tierney announced on Tuesday he is withdrawing support for a proposed Portland streetcar line extension into the city. The announcement from the elected official, who had the swing vote when the city council pushed the proposal forward last April, likely means a delay to Lake Oswego streetcar plans indefinitely. The Portland-Lake Oswego streetcar project appears to be dead -- or at least suspended -- after losing suburban political support. "Until we are more united as a city, as a region, and as a city council, I believe we should in the near term, put this project on the shelf," said Tierney. "Leave it for a future council to examine if they choose to and cease direct expenditures in the foreseeable future." Tierney cited a weak economy, a deep split in public opinion and a need for Lake Oswego officials to focus on more immediate city needs as his reasons for changing his mind. He also mentioned that he informed Mayor Jack Hoffman of his decision before announcing it at the meeting. "We need to further refine what our community should be," said Tierney. "Right now, this council is too divided to move ahead with bold plans." Councilor Sally Moncrieff, another firm supporter of the project, also appeared to be withdrawing her support on Tuesday saying she agreed with Tierney that now is not the right time for a streetcar in Lake Oswego. "I still believe very firmly that the streetcar project is an excellent project and that's it's the right project for Lake Oswego but it's always been contingent on being financially feasible," she said. "It takes all of the partners being ready to go at the same time." The streetcar proposal was the most high-profile of available options presented in the Lake Oswego to Portland Transit Project. The initiative looked to present transit alternatives to alleviate traffic congestion along Oregon 43. An enhanced bus system was another option that was on the table. The Lake Oswego streetcar proposal encountered opposition from many city property owners who expressed concerns over issues such as the project's initially projected $458 million price tag by a planned completion date in 2017 to potential quality of life and environmental concerns. A community survey conducted late last year of 300 registered Lake Oswego voters found 52 percent of respondents opposed the project. View full sizeThe OregonianPlans for a Portland streetcar extension into Lake Oswego took a hit on Tuesday after Lake Oswego Councilor Bill Tierney announced he no longer supported the project. The move likely puts the project on hold indefinitely. However, supporters of the plan believed the streetcar could be the key to revitalizing the city's population and economic opportunities. The Lake Oswego City Council approved a framework plan in late November to redevelop the city's 107-acre Foothills district into a mixed-use area for housing, retail and offices with the streetcar as one of its main attractions. Hoffman, who voted last year for the city to continue exploring the streetcar option, said the advisory vote and other issues will have to be re-evaluated in the coming days and weeks. "I still think this is a great project, as everybody knows," said Hoffman on Tuesday. "I think the timing is problematic with the economy, TriMet's issues and other issues. But I think we need to keep in mind the transportation land use connection and that Foothills is still a project we need to keep moving forward on." Former Lake Oswego Mayor Judie Hammerstad, a strong streetcar proponent, said she’s hard-pressed to think of a better transit alternative for the city. “It’s my view that this is a project that doesn’t have to happen today, but it’s got to happen in the next few years,” she said. “I don’t see any other transportation projects for Lake Oswego that can bring to the table what the streetcar can – and the window to do it is closing.” Councilor Gudman said he had no idea Tierney's announcement was coming but applauded his colleague for "having a change of heart." "It's always difficult for someone to change their mind," said Gudman after the meeting. "But this now permits us to move forward and use our limited resources on a variety of other projects that could be much more beneficial to Lake Oswego." "But the project is dead, there's really no need to gloat," he added. Councilor Mary Olson, another streetcar opponent, said she would have liked to have seen an announcement like this come a year ago. "It's a good thing this is coming to an end," she said. "

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stress (WAS) daily for 10 consecutive days. The abdominal withdrawal reflex (AWR) to colorectal distension was assessed at the end of the 10-day period. Western-blotting analysis was applied to investigate the alterations of TRPV1 and TRPA1 in the colonic afferent dorsal root ganglia (DRG). Compared with control rats, the WAS-treated rats demonstrated a significant increase in the AWR with the pressure > or = 40 mm Hg (P < 0.05). Meanwhile, in the WAS-treated rats, western-blotting analysis showed significant upregulation of TRPV1 and TRPA1 in the colonic afferent DRG. The results indicate that WAS could induce the upregulation of TRPV1 and TRPA1 in the colonic afferent DRG, and both receptors may be candidate molecules involved in the stress-induced visceral hyperalgesia in rats.Connie Morella Visits Law Library on March 18, 2009 Former Maryland Congresswoman Connie Morella Discusses Her Legislative Experience Working for Women, Children and Families On Wednesday, March 18, acting Law Librarian of Congress Charles Doyle and Associate Librarian of Congress Deanna Marcum will welcome the Honorable Constance ‘Connie’ Morella as she presents “Legislating in Heels – An Anecdotal Journey.” The event will take place between 1:00 and 2:30 pm at the Whittall Pavilion, located in the Jefferson Building on 1st Street SE between Independence Avenue and East Capitol Streets in Washington, D.C. When she began her lengthy tenure in Congress in 1987, there were only 24 women in the House. Upon her departure 16 years later, that number increased to 62. Her presentation will be a fitting tribute to the accomplishments of women during National Women’s History Month. Prior to her service as Ambassador to the Organization for Economic Cooperation and Development from 2003 to 2007, Ms. Morella served in Congress, chairing the Congressional Caucus for Women’s Issues and sponsoring the 1992 Battered Women’s Testimony Act and the Judicial Training Act, both having important repercussions for women in the court system due to domestic violence. Ms. Morella also served in the Maryland House of Delegates from the 16th District. The event is free and open to the public but seating is very limited and advance reservations are suggested at (202) 707-9834, [email protected]. Request ADA accommodations five business days in advance at (202)707-6362 or [email protected] Founded in 1832, the Law Library of Congress makes its resources available to members of Congress, the Supreme Court, other branches of the U.S. Government and the global legal community, and sustains and preserves a universal collection of law for future generations. With more than 2.6 million volumes, the Law Library contains the world’s largest collection of law books and other resources from all countries and provides online databases and guides to legal information worldwide through its Web site.Mustang Original Studded Seat Overview of Mustang Original Studded Seat Mustang Motorcycle Products, Inc. is a world leader in the design and construction of motorcycle seats. Since 1980, Mustang has been proud of making the highest quality, most comfortable seats available and offering them at reasonable prices. Mustang motorcycle seats are designed for all-day riding comfort for both the driver and passenger. Every Mustang seat is made in the United States by true craftsmen who take pride in transforming the highest quality, raw materials into a finished product. Full front bucket for comfort Passenger seat angles forward to support drivers back Functional skirt flows over frame and fender to give a smooth, clean looktalkingrobocop's podcast Wherein Kit Power watched the movie Robocop with a different guest each month and records the resulting conversation. Occasional bonus podcasts feature returning guests picking a different movie to watch. Made possible entirely as a result of Patreon funding - www.patreon.com/kitpower. Sign up for only a $1 a month for early access and exclusive content. Categories Welcome to the fourth episode of Watching Robocop with Kit Power! This month, I am delighted to be joined by Renee Pickup, a superb author, non-fiction writer, blogger and podcaster with strong opinions and excellent taste in movies. Join us, and discover: Renee's 'not enough violence in movies' theory Kill Bill and why you never dis Con Air An exciting new fan theory about Clarence's nose And SO much more. Enjoy! And as ever, thank you for your support. :) For more of Renee's blogging and podcasting, please head on over to her webpage. My monthly Ginger Nuts Of Horror blog ‘My Life In Horror’, which kicked off this whole thing, can be found here. Theme tune provided with the kind permission of The Disciples of Gonzo, from their track Superhero. Listen to more from them here. If you enjoyed this podcast and would like to contribute financially to the monthly production costs, in exchange for early access to both this show and my written work, as well as snazzy exclusives, please see my Patreon. Welcome to the first ever bonus episode of the podcast! Thanks to the amazing generosity of my Patreon backers, I am going to be releasing these bonus episodes on a bi-monthly basis, in which returning guests get to pick THEIR favourite movie to talk about. In our first bonus 'cast, Daniel Harper returns to talk about his childhood love affair and obsession with Terminator 2: Judgement Day. Amongst many revelations, discover: How there are, in fact, only two Terminator movies Vonnegut's holy word Kit outing himself as a human chauvinist And much, much more. Enjoy! :) For more of Daniel's blogging and podcasting, please head on over to his page on Eruditorum Press. My monthly Ginger Nuts Of Horror blog ‘My Life In Horror’, which kicked off this whole thing, can be found here.The present invention relates to an improved mounting arrangement for a measuring device of the type comprising a measuring scale, a carrier which supports the measuring scale, and at least one clamping element for fasting the carrier to a mounting surface of one of two objects, the relative position of which is to be measured. German Pat. No. 27 12 422 discloses a length measuring system which includes a housing that surrounds the measuring scale and the scanning unit. This housing is fastened by means of screws to a machine part. German Pat. No. 25 05 585 discloses a length measuring system in which a housing, which encloses both the scale and the scanning unit, is fastened at both ends to a machine part by means of angle brackets which define in the vertex region a joint in the form of a groove. German Pat. No. 26 30 880 discloses a length measuring system in which the housing, which encloses both the scale and the scanning unit, is fastened at both ends to an object to be measured by means of ball joints. In the measuring systems described above, precisely positioned bores must be provided for the fastening of the housing to the object to be measured, both in the housing and also in the object. The formation of such precise bores represents a considerable expense in many applications. The document "Messen und Prufen/Automatik", July and August 1974, page 438, FIG. 12a, discloses a known practice for fastening a scale to a narrow supporting surface of a machine part by means of clamping shoes positioned at one side of the scale. In this arrangement high contact pressure forces of the clamping shoes against the scale are needed to hold the scale carrier in engagement on the supporting surface in the face of vibrations and joltings of the machine. German DE-OS No. 38 08 384 discloses a measuring arrangement in which a scale carrier defines on both side surfaces a lateral groove. Clamping shoes engage this lateral groove in order to fasten the scale carrier to a machine part. This arrangement provides a secure seating of the scale carrier on the machine part, but is relatively expensive in construction and requires considerable space to implement.Molecular analysis of point mutations in a barley genome exposed to MNU and gamma rays. We present studies aimed at determining the types and frequencies of mutations induced in the barley genome after treatment with chemical (N-methyl-N-nitrosourea, MNU) and physical (gamma rays) mutagens. We created M(2) populations of a doubled haploid line and used them for the analysis of mutations in targeted DNA sequences and over an entire barley genome using TILLING (Targeting Induced Local Lesions in Genomes) and AFLP (Amplified Fragment Length Polymorphism) technique, respectively. Based on the TILLING analysis of the total DNA sequence of 4,537,117bp in the MNU population, the average mutation density was estimated as 1/504kb. Only one nucleotide change was found after an analysis of 3,207,444bp derived from the highest dose of gamma rays applied. MNU was clearly a more efficient mutagen than gamma rays in inducing point mutations in barley. The majority (63.6%) of the MNU-induced nucleotide changes were transitions, with a similar number of G>A and C>T substitutions. The similar share of G>A and C>T transitions indicates a lack of bias in the repair of O(6)-methylguanine lesions between DNA strands. There was, however, a strong specificity of the nucleotide surrounding the O(6)-meG at the -1

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citizens, hear me! I have discovered evidence — undeniable, incontrovertible proof of this very conspiracy!" The audience surged and muttered, their cries blending into a dull roar. I remembered the crowd on the day of the Funeral Riot — the many-headed enemy. The City Guards moved forward, positioned to intercept any movement from the audience, but Orelia held them back with a signal. They'd be no help if things got too tight. For right now, we — Terris and I — were down here and the crowd was up there, and we had a precious little space between us. Not even a pea-brained twitterbat would call that an advantage. On a signal from Montborne, a City Guard marched down a side aisle and up to the table. Had Montborne somehow gotten Orelia to do his dirty work for him? The Guard wore a patch over one eye and carried two long, slender leather-wrapped bundles. I didn't like the look of this at all. Neither, apparently, did the rest of the Inner Council. A few of the Senators rose to their feet in protest. At my side, Terris turned pale. The one-eyed Guard unwrapped the two bundles and laid them on the table in front of the general. I did not need to look to know what they were. One of them had an official-looking card tied to it. Montborne picked up the tagged dagger. With a dramatic flourish, he lifted it overhead, the slender blade catching the light, and laid on the oval table. "This is the norther dagger that killed Pateros! "And this — " he picked up the second blade and held it high, with exactly the same gesture. If I'd blinked, I wouldn't have known it was different except for the tag fluttering like a rock-dove pinion. The crowd held its breath as he set the second dagger down. "Unbelievable as it sounds, yesterday this _exact duplicate_ was smuggled into Laureal City — " The audience rumbled like an avalanche about to bust loose. Montborne held them back with a gesture. " — and discovered, hidden... _in the possession of that man!_ " He whirled and pointed straight at Terris. # Chapter 40 Montborne's voice thundered above the general outcry. "I accuse Terricel sen'Laurea, who just yesterday returned from a secret mission to our norther borders." Esmelda stood motionless, as she had through Montborne's entire speech, but now the Councillor in the fancy neck chain pushed forward and gestured for order. Terris tensed, ready for action. I grabbed his shoulder and held him firm. Anything he said would only make things worse. It was only one small step to ask _Who sent Terris north?_ Montborne meant to bring Esmelda down as well, or else tie all Laurea into knots trying. By the time things got sorted out, he aimed to be in control, and no one would remember that Esmelda had also made accusations against him. "These allegations are outrageous!" cried Hobart, the fancy-chained Councillor. "Outrageous and monstrous!" "But if they're true?" demanded Orelia, rising and pounding the table so that water splashed from the silver ritual bowl. _"What if they're true?"_ Ah, so that was how Montborne had gotten to her. " _Truth?_ You want the truth?" Quick as a striking snake, Esmelda seized the opening. Any other time, the old dragon might have gotten the room back under her control. The Inner Council would have listened, as well as half the Senators. I caught the flashes of unguarded feeling on their faces, fear and suspicion warring with the bone-deep need to believe in her. But the crowd at the back and up on the balconies, the many-headed monster, wavered on the very edge of riot. "Truth is not something to be determined by a popularity contest." Esmelda's voice sliced through the uneasy murmurs. "Montborne has raised some very serious charges, charges that bear on the very heart and future of our nation. These charges merit the most thorough and careful investigation. How can we possibly do them justice here, bandying them about like a pack of irresponsible playground insults?" A few people in the front rows sat down again. A Senator in the front row wiped his florid cheeks with a handkerchief, as if the sudden reversal was too much for him. "These allegations will be heard in the proper time and setting," Esmelda went on, " _as well as_ evidence that the weapons produced by Montborne were manufactured right here in Laureal City — in a secret military facility — under the orders of General Montborne himself." "Impossible!" Montborne shot back, still brandishing the second dagger. "Any fool can see these are _norther_ daggers!" "If the distinguished general will kindly —" Hobart, the Senate Presidio, tried again. Esmelda made a slashing gesture with her hands. Suddenly the doors under the spectators' balconies flew open. Head high, Avi strode down the wide central aisle, Jakon and Grissem only a pace behind her. In their quilted vests and elkskins, their hair like spun gold, faces stern, they seemed proud and strange but not, as Montborne said, savage. I'd fought as hard as anybody at Brassaford, I'd spilled as much blood, but I knew now what _savage_ really was. The entire chamber went wild — people screaming, jumping up and waving their arms, ushers vainly trying to calm them, Senators and Councillors calling for order, the priest chanting, Montborne's men looking confused and astonished, some of them unnerved — the whole mess worse than a barnfowl coop after a raptor bat has just swooped in, and twice as brainless. A bunch of spectators rushed for the doors, but Orelia motioned her people forward. They moved quickly to hold back the worst of the panic. Me, I was on my feet with one hand on my long-knife hilt and the other on Terris's shoulder, grimly counting how many throats I'd have to cut to get him out of there alive. In front of the oval Inner Council table, Esmelda waited, still as a carven statue. The two northers had turned round to face the audience, Avi between them. They stood, legs apart, balanced lightly on the balls of their feet, arms folded across their chests. It was too bad, I thought, that Jakon couldn't dance for the crowd — then they'd really sit up and notice. How it happened, I didn't know — whether it was something Esmelda did or the strength of her presence or the northers' inhuman calm, or maybe just plain curiosity winning out over batshit stupidity, but the room grew quiet again. People cleared the aisles and sat down, some still pointing and whispering to their neighbors, others hushing them up. Montborne glanced around — he knew the moment had gone to Esmelda. Behind that waxy-smooth face, I sensed him juggling for another opening, trying to outguess what she'd try next. Esmelda's voice was intense, but clear and low, as if she had no need to shout or make dramatic gestures. It was enough to talk as she did about desperate times, about hope and dreams. She was no Pateros, even I saw that. Pateros could take someone like me and make me think I could do great things — Esmelda made these people think _she_ could. For this time and place, though, it was enough. If Avi could do the same thing, she could also sign that treaty with Jakon's people, marry him, and bear a half-norther heir to succeed her as Guardian. Maybe there was a chance for peace with the north after all. After a moment or two, I caught the change in the faces of the crowd. Most of them were children when Esmelda stood out there on the plaza and the rains came down to put out the foundry fires and the plague ended. Yet they seemed to somehow remember, as if that history were bred into their blood. As if to underscore the mystery of Jakon and Grissem, she began by reminding the audience of the long history of conflict between Laurea and the north. Times I'd never heard of, not being a scholar, things that happened hundreds of years ago. And Brassaford. Ah yes, these people remembered Brassaford. A murmur passed through the room like a gust of bitter wind and then as quickly died down. If Jakon or Grissem felt it, they gave no outward sign. "And so, we come to the present," Esmelda said. "To here and now. To today." A few people in the balconies grumbled, impatient for answers to the questions Montborne had raised. The Senators, who knew the rhythms of official speech, settled down to listen. Orelia and some of the Inner Council members leaned forward expectantly. "Let us consider the northers as they are today. Let us consider _these_ northers

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is uniquely vibrant! Handcrafted by a women's cooperative in India that employs low-income women. Size: 21" in length with 2.5" extender **Learn more about WorldFinds and the artisans who made this product. Three strands of upcycled Kantha fabric beads are punctuated by a larger bead, and come together with a brushed gold metal ring at the center. Uneven, linear rows of Kantha beads hang from the ring, forming a fringe. Each necklace will vary slightly, as the Kantha beads are repurposed. The beads are made by wrapping Kantha fabric around tiny wooden beads. Handmade by women artisans in India who improve their lives and communities through fair trade. Size: Measures 26” long plus a 2” extender. **Learn more about WorldFinds and the artisans who made this product. Large, lightweight golden hoop earrings featuring colorful beads made from recycled Kantha fabric wrapped around wooden beads. Colors and patterns will vary slightly. Handmade by women artisans in India who are working to improve their lives through fair trade. Size: 3" from top of earring **Learn more about WorldFinds and the artisans who made this product. Three geometric points of recycled Kantha beads hang below a strand of brass triangles. Each necklace will vary slightly, as the Kantha beads are repurposed. Handmade by women artisans in India who are improving their lives and communities through fair trade. Size: 20"; with 2" extender **Learn more about WorldFinds and the artisans who made this product. Three strands of recycled Kantha textile beads are linked with gold metal wires and complimented by gold chain fringe hanging from the longest strand. Each necklace will vary slightly, as the Kantha beads are repurposed. Handmade by women artisans in India who improve their lives and communities through fair trade. Size: Measures 16” at shortest strand + 4 ½” extender. **Learn more about WorldFinds and the artisans who made this product. This graduated strand of recycled kantha beads alternate with tiny golden beads to form a necklace that crescendos at the center. Colors and patterns vary, but each necklace is vibrant. Handcrafted by a women's cooperative in India that employs low-income women. Size: 22" in length with 2.5" extender **Learn more about WorldFinds and the artisans who made this product. This colorful rainbow kantha bracelet comes with a tag which reads, "Unity encourages harmony and intention. This Unity Bracelet inspires us to trust that together we are greater than the sum of our parts." Measures ¼”; stretches to fit most wrists. Sustainably handmade by women artisans in India who are working to improve their lives through fair trade. **Learn more about WorldFinds and the artisans who made this product. Festive stars made from nickel-plated brass with glass panels on front and back, and open on the sides. They make a lovely glow when lit with an LED candle. Comes on a 15" chain with hook for hanging. LED tea lights recommended.Murders that many saw coming Ahn In-deuk didn’t look good.And his older brother knew that could mean trouble - violent trouble.It was early this month, and the older brother - who asked that his name be withheld in interviews with the JoongAng Ilbo - concluded that the 42-year-old Ahn was on a downward spiral. He needed to do something before Ahn caused harm, as he had in the past.The older Ahn phoned a psychiatric hospital in Jinju, South Gyeongsang, on April 5. He wanted to have his brother hospitalized.He asked the Jinju hospital for records showing that Ahn was treated there for schizophrenia for six months from late 2011. The older brother was also trying to disguise his own role in having his younger brother hospitalized - in case he retaliated someday.The hospital made clear it could not help, no matter how hard he insisted. The older Ahn needed to produce a power of attorney for his brother - or the younger Ahn had to personally visit the hospital to claim his records.Twelve days later, the younger Ahn poured gasoline around the living room of his fourth floor apartment in Jinju, set fire to a piece of newspaper and hurled it on the flammable liquid at around 4:30 a.m. He walked down to the second floor of his building and allegedly stood near a staircase, stabbing neighbors trying to escape to safety.Five were killed, including a 12-year-old girl, and six were injured.His older brother had been correct. Ahn descended into homicidal madness.Ahn’s neighbors are criticizing local police for having ignored their complaints about his increasingly erratic and disturbing behavior. Neighbors called the police number, 112, six times since he moved into the apartment complex in Jinju in December 2015. Most of the calls were made within the past year.Yet Ahn was charged only a single time for property damage after he was caught on CCTV throwing his own feces at the door of an upstairs neighbor. That was on March 12 - a month before the fire and killings. The CCTV was installed by the neighbor to gather proof of Ahn’s threats. Ahn was caught on camera following the neighbor’s 18-year-old niece, who was living in the apartment. That niece was fatally stabbed allegedly by Ahn on March 17.Now, the suspect’s brother is taking a jab at the country’s medical system, claiming he tried to force the younger Ahn into receiving treatment in the weeks before the tragedy, but failed due to red tape.The first time Ahn was officially diagnosed with schizophrenia was 2010, after he was criminally charged with slashing a college student he didn’t know in the face with a knife in downtown Jinju. He was convicted of assault, sentenced to two years in prison with a three-year probation, and sent to the National Forensic Psychiatry Hospital in Gongju, South Chungcheong, a mental hospital run by the Ministry of Justice for criminals with mental illnesses.After Ahn was discharged, his family forced him into a psychiatric hospital in Jinju in late 2011. Families of a schizophrenic patient can hospitalize their relative if, among other circumstances, two immediate family members agree to the admission. After six months of treatment, Ahn was discharged in 2012. Through July 2016, he received outpatient treatment from the Jinju hospital.That was the last medical attention Ahn ever sought. He told his family he didn’t want to take medication because it made him feel disoriented, especially at work.His symptoms grew worse and he began bullying his neighbors in mid-2018. His brother tried to help but Ahn refused to seek treatment. He held a grudge against his family after they forced him into the hospital in 2011.After the brother’s entreaties to the Jinju psychiatric hospital on March 5 failed, he got in touch with the local prosecutors’ office, wondering if it could force his brother to receive treatment. It was another dead end, and prosecutors told him to try the Jinju city government or the younger Ahn’s community center instead.The community center said it could do nothing. A worker at the community center said he previously worked for the city government and knew the system well. But he doubted Jinju City Hall could help with such a delicate and serious request.The older Ahn learned that, under the law, the Jinju mayor had the authority to force Ahn into hospitalization. He made a request, which was rejected for an unspecified reason.According to interviews conducted by the JoongAng Ilbo with numerous people who know the younger Ahn, including his mother, Ahn was introverted and didn’t have many friends as a young child, but didn’t get into trouble. The family was poor, and when Ahn graduated from middle school in 1993, he decided to start working. (High school education is not compulsory in Korea.) Ahn mostly worked in factories.In his early 20s, Ahn injured his back at a factory in Gimhae, South Gyeongsang. He tried to get compensation for the accident from the company, but failed.According to people who knew him, that’s when his personality took a turn for the worse.Ahn moved from one factory to another, until 2008, at age 31, he hurt his back again at a factory run by a conglomerate in Changwon, South Gyeongsang. Ahn applied for compensation again, and failed.He became angry.After he was discharged from the Gongju mental hospital in 2011, Ahn started punching passersby for no reason. Ahn has told police and the local press that he committed his alleged murders “out of anger” because he had been “disadvantaged” by the Jinju city government, society and former employers, without detailing how. Police are looking into the possibility that his failures to receive workplace compensation could have been the prime source of his rage.BY SHIN SUNG-SIK, LEE EUN-JI, KIM YOON-HO AND NAMGUNG MIN [[email protected]]I[NTRODUCTION]{.smallcaps} {#sec1-1} ========================== Congenital adrenal hyperplasia (CAH) describes a group of inherited autosomal recessive disorders affecting adrenal steroid synthesis. The most frequent CAH variant, accounting for 95% of all affected patients, is 21-hydroxylase deficiency (21-OHD) and caused by inactivating mutations in the 21-

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ings can quote every line of both movies. "We've got the tools, we've got the talent. It's Miller time...." Smooth solve from here. Thanks, Dan. Once again, didn't get theme 'til it was over. I'll have to work on that. This oldstress did know Mortimer 1A SNERD with his nerdy buck-tooth and Jacques Brel (36A IFWE)who "is alive and well and living in" the minds of those who loved him. Wish you had a picture of the dummy, and a video of Brel (especially the really weird - or wired - "Amsterdam").Likewise, did not know 13A TAKEI or Lucy 20D LIU. Must learn. I liked this puzzle and thanks PG for the write up. ARRAS was familiar for several reasons. Years ago I saw the wonderful Arras tapestries in The Cloisters (part of Met. Mus. of Art) in NYC and I lived one summer on Rue d'Arras in Paris. Arras is also a city in northern France, the birthplace of Robespierre. Loved the reference to Pee Wee REESE a great player with the old Brooklyn Dodgers. I"ve had a CAT scan but didn't know AXIAL, and REFLUX, I don't want to talk about. ALGER HISS recalls the communist hysteria of th "50's. I like it when full names are in puzzles. ARRAS is a word i've only ever heard (and used) in the context of hamlet. polonius is hiding behind the ARRAS in gertrude's bedroom when hamlet hears him and stabs him through it. moral of the story: don't hide behind the ARRAS, especially when there's a moody armed dane milling about. this was one of my faster LAT paper solves; as soon as i got RUSSELL CROWE and the M of MUSSEL SHELL, i knew what the theme would be, and promptly wrote in RUSTLE CATTLE and MUSCLE CRAMP. the only thing that kept me from breaking a personal best was the fact that i originally tried to write in RUSSEL CROWE and ... it didn't fit. erasing cost me about 10 seconds, not much in the grand scheme of things, but when you've got your ears pinned back to go for maximum speed, that's a big deal. oh, and one other mild hangup: because it was a dan naddor, i was expecting AT IT AGAIN and CRAPSHOOT to be part of the theme also. but i'm actually pleased that they weren't, because those are great fill entries. I learned ARETE from crosswords. It should have a little hat (circumflex accent) over the first e....ARÊTE. According to online dictionaries, it is pronounced uh-RATE. Here is a photo of Half Dome in Yosemite National Park with Clouds Rest arête in the background. I worked this puzzle without any real trouble although I initially put NANO for Mork's signoff before remembering it's NANU. ARRAS was a new word for me and I had the same questions noted above re: GLADIOLA (gladiolus, gladioli, gladiolas, gladioluses?) I guess it's safe to call them glads. had reactions similar to those of sfingi, parsan, david; very pleasant puzzle, thank you Dan Naddor and even better write-up< PG! Guess I missed the Crosswordese on TETRA. And PSEUD? New one...Particularly liked: SNERD, ARRAS (now I know what they are), MACHISMO, ATITAGAIN, GLADIOLA, AXIAL, DILEMMA and ALGERHISS, which may have presented a real problem to those not of a certain age... For anyone who is interested in learning more about Alger Hiss, I recommend Sam Tanenhaus's (he edits the NYT Sunday Book Review) biography of Whittaker Chambers.. I too didn't really catch the pairing/rhyming of the theme until coming here. I see the first words rhyme but...And is it Edgar Allan Poe month? All said, another encouraging LA Times puzzle, beginning to atone for some recent let-downs- you know, the idiom "pin one's ears back" does not mean anything at all like what i thought it meant. at least according to online dictionaries. my mac's built-in dictionary says it means "to listen carefully." i can also find "to give a person a sound beating" and "to scold severely" for pin someone's ears back. it's also apparently a literal phrase for a type of elective surgery for people whose ears stick out. i have only ever heard it used to describe pass rushers in football, who are said to "pin their ears back" and go after the QB on obvious passing downs, abandoning any responsibility for stopping the run. i'm not exactly sure why this would help them (less air resistance, perhaps?), but idiom is a strange thing. trying to solve a puzzle on paper in under 3 minutes is a slightly frightening experience. i feel like i'm careening out of control much of the time, and it always seems like a small miracle if the letters even end up in the boxes, to say nothing of whether they're actually correct. When I was a young pup, my grandfather (one of the largest wholesale flower growers in the West) would have scolded me if I had ever called it GLADIOLA. One GLADIOLUS, more than one GLADIOLI, was the one true path. Or, when talking to the hired help, they were often just GLADS, as in "time to pick the glads." One of my slowest solves in ages...felt like I was solving in mud or something. Joon, I've watched a lot (A Lot) of football, and I don't remember _ever_ hearing that expression. There's a ton of support for it online (if you search with football, otherwise you just get bilateral otoplasty info), so I wonder why? I should say I've watched a lot of _pro_ football, maybe it tends to be a college expression? It's probably just that I'm not auricularly observant. Many animals "pin their ears back" as an indication of anger, intent to attack, or while attacking. It's a clear sign of iminent attack should a dog, cat, horse, etc. pin their ears back. Hence its comming into common usage to go on the attack. Further, in the animal world, it's a matter of self preservation - if your ears are pinned back, they're less likely to be bitten off in the ensuing fight. Or, in my case, they just stick out so damned far. @Joon - I used gum. Before I was dead and all. My left ear involuntarily goes back when I hear a loud noise behind me. (Throwback to ape ancestors.) I can also move it voluntarily. I used to think that "prick up your ears," referred to that, until I found it didn't happen to other people. @ddbmc -I would love to be able to embed. But, as far the circumflex, I have a Character Map which I load to the side, hit on the character, select it, and drop and drag. ê @Parsan. In the '60s, I was at the Cloisters viewing the Unicorn Tapestries which shows the capture of the unicorn (shut up Freud). A 4-yr-old girl was in front of the one showing the capture and wounding, and she was crying for the unicorn with her mother telling her the unicorn was ok. I marveled at the message sent across 5 centuries.I only know PeeWee Reese because his name rhymed with my sister's, so we had to hear it all the time. Alger Hiss is referred to at pumpkin time! Lick should be on the puzzle with RNA and DNA. @Embien - thanx for glad info. @Orange - I guess there are many new abbrevs. Back in my day, we didn't even have adolescent literature, so I took a 3-credit.Likewise, I'll have to find a newer list to study. seth, am i imagining things or did jaws use "pin their ears back" to describe freeney and mathis going after pennington in the 4th quarter last night? in any event, it's a turn of phrase i associate with football writers more than announcers. i think doug farrar over at football outsiders is the first one i can remember using it.South Delhi South Delhi is an administrative district of the National Capital Territory of Delhi in India. It is bounded by the Yamuna River to the east, the districts of New Delhi to the north, Faridabad District of Haryana state to the southeast, Gurgaon District of Haryana to the southwest, and South West Delhi to the west. South Delhi has a population of 2,731,929 (2011 census), and an area of , with a population density of 9,034 persons per km² (23,397

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'__builtin_ia32_cmpngess': '_mm_cmpnge_ss', '__builtin_ia32_cmpordss': '_mm_cmpord_ss', '__builtin_ia32_movss': '_mm_move_ss', '__builtin_ia32_movsd': '_mm_move_sd', '__builtin_ia32_movhlps': '_mm_movehl_ps', '__builtin_ia32_movlhps': '_mm_movelh_ps', '__builtin_ia32_movqv4si': '_mm_move_epi64', '__builtin_ia32_unpckhps': '_mm_unpackhi_ps', '__builtin_ia32_unpckhpd': '_mm_unpackhi_pd', '__builtin_ia32_punpckhbw128': '_mm_unpackhi_epi8', '__builtin_ia32_punpckhwd128': '_mm_unpackhi_epi16', '__builtin_ia32_punpckhdq128': '_mm_unpackhi_epi32', '__builtin_ia32_punpckhqdq128': '_mm_unpackhi_epi64', '__builtin_ia32_unpcklps': '_mm_unpacklo_ps', '__builtin_ia32_unpcklpd': '_mm_unpacklo_pd', '__builtin_ia32_punpcklbw128': '_mm_unpacklo_epi8', '__builtin_ia32_punpcklwd128': '_mm_unpacklo_epi16', '__builtin_ia32_punpckldq128': '_mm_unpacklo_epi32', '__builtin_ia32_punpcklqdq128': '_mm_unpacklo_epi64', '__builtin_ia32_cmpeqpd': '_mm_cmpeq_pd', '__builtin_ia32_cmpltpd': '_mm_cmplt_pd', '__builtin_ia32_cmplepd': '_mm_cmple_pd', '__builtin_ia32_cmpgtpd': '_mm_cmpgt_pd', '__builtin_ia32_cmpgepd': '_mm_cmpge_pd', '__builtin_ia32_cmpunordpd': '_mm_cmpunord_pd', '__builtin_ia32_cmpneqpd': '_mm_cmpneq_pd', '__builtin_ia32_cmpnltpd': '_mm_cmpnlt_pd', '__builtin_ia32_cmpnlepd': '_mm_cmpnle_pd', '__builtin_ia32_cmpngtpd': '_mm_cmpngt_pd', '__builtin_ia32_cmpngepd': '_mm_cmpnge_pd', '__builtin_ia32_cmpordpd': '_mm_cmpord_pd', '__builtin_ia32_cmpeqsd': '_mm_cmpeq_sd', '__builtin_ia32_cmpltsd': '_mm_cmplt_sd', '__builtin_ia32_cmplesd': '_mm_cmple_sd', '__builtin_ia32_cmpunordsd': '_mm_cmpunord_sd', '__builtin_ia32_cmpneqsd': '_mm_cmpneq_sd', '__builtin_ia32_cmpnltsd': '_mm_cmpnlt_sd', '__builtin_ia32_cmpnlesd': '_mm_cmpnle_sd', '__builtin_ia32_cmpordsd': '_mm_cmpord_sd', '__builtin_ia32_cvtsi642ss': '_mm_cvtsi64_ss', '__builtin_ia32_cvttss2si64': '_mm_cvtss_si64', '__builtin_ia32_shufps': '_mm_shuffle_ps', '__builtin_ia32_shufpd': '_mm_shuffle_pd', '__builtin_ia32_pshufhw': '_mm_shufflehi_epi16', '__builtin_ia32_pshuflw': '_mm_shufflelo_epi16', '__builtin_ia32_pshufd': '_mm_shuffle_epi32', '__builtin_ia32_movshdup': '_mm_movehdup_ps', '__builtin_ia32_movsldup': '_mm_moveldup_ps', '__builtin_ia32_maxps': '_mm_max_ps', '__builtin_ia32_pslldi128': '_mm_slli_epi32', '__builtin_ia32_vec_set_v16qi': '_mm_insert_epi8', '__builtin_ia32_vec_set_v8hi': '_mm_insert_epi16', '__builtin_ia32_vec_set_v4si': '_mm_insert_epi32', '__builtin_ia32_vec_set_v2di': '_mm_insert_epi64', '__builtin_ia32_vec_set_v4hi': '_mm_insert_pi16', '__builtin_ia32_vec_ext_v16qi': '_mm_extract_epi8', '__builtin_ia32_vec_ext_v8hi': '_mm_extract_epi16', '__builtin_ia32_vec_ext_v4si': '_mm_extract_epi32', '__builtin_ia32_vec_ext_v2di': '_mm_extract_epi64', '__builtin_ia32_vec_ext_v4hi': '_mm_extract_pi16', '__builtin_ia32_vec_ext_v4sf': '_mm_extract_ps' } # Special unhandled cases: # __builtin_ia32_vec_ext_*(__P, idx) -> _mm_store_sd/_mm_storeh_pd # depending on index. No abstract insert/extract for these oddly. unhandled = [ '__builtin_ia32_vec_ext_v2df', '__builtin_ia32_vec_ext_v2si', ] def report_repl(builtin, repl): sys.stderr.write("%s:%d: x86 builtin %s used, replaced with %s\n" % (fileinput.filename(), fileinput.filelineno(), builtin, repl)) def report_cant(builtin): sys.stderr.write("%s:%d: x86 builtin %s used, too many replacements\n" % (fileinput.filename(), fileinput.filelineno(), builtin)) for line in fileinput.input(inplace=1): for builtin, repl in repl_map.iteritems(): if builtin in line: line = line.replace(builtin, repl) report_repl(builtin, repl) for unh in unhandled: if unh in line: report_cant(unh) sys.stdout.write(line) sys.exit(err) After sinking over 60 percent from its December high to its February low, bitcoin is showing signs of life. The cryptocurrency is now up about 35 percent since it sank below $6,900 on Feb. 5, and one market watcher who correctly called the rally says there's even more room to run. After the Feb. 5 low, Blue Line Futures President Bill Baruch told CNBC's "Trading Nation" he saw a move up back up to $10,000. At that time, bitcoin was trading around $7,200. Tuesday morning, bitcoin was trading above $9,200, representing roughly 28 percent upside since that time. Here's his latest bull case. • Participation in the rally has been broad-based, with several so-called alt-coins gaining in value recently. This is seen as a bullish catalyst for the entire cryptocurrency space. • Bitcoin has seen a bounce from its 2018 lows even in the face of ongoing regulatory concerns, including a new inquiry from New York Attorney General Eric Schneiderman into exchanges like Gemini and Coinbase's GDAX exchange. • The $10,000 level has represented strong resistance, but once that level is breached to the upside, Baruch sees a trade around $11,500 per coin. Bottom line: Baruch sees further upside for bitcoin after a sizable rally from its 2018 lows.I just had my first MRI in April and I

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— 10 years before the start of the Great Depression in 1919, when they independently warned that going back on the gold standard at the post-World War I price level (in terms of gold) — about twice the pre-War price level — would cause a disastrous deflation unless the world’s monetary authorities took concerted action to reduce the international monetary demand for gold as countries went back on the gold standard to a level consistent with the elevated post-War price level. The Genoa Monetary Conference of 1922, inspired by the work of Hawtrey and Cassel, resulted in an agreement (unfortunately voluntary and non-binding) that, as countries returned to the gold standard, they would neither reintroduce gold coinage nor keep their monetary reserves in the form of physical gold, but instead would hold reserves in dollar or (once the gold convertibility of sterling was restored) pound-denominated assets. (Ron Batchelder and I have a paper discussing the work of Hawtrey and Casssel on the Great Depression; Doug Irwin has a paper discussing Cassel.) After the short, but fierce, deflation of 1920-21 (see here and here), when the US (about the only country in the world then on the gold standard) led the world in reducing the price level by about a third, but still about two-thirds higher than the pre-War price level, the Genoa system worked moderately well until 1928 when the Bank of France, totally defying the Genoa Agreement, launched its insane policy of converting its monetary reserves into physical gold. As long as the US was prepared to accommodate the insane French gold-lust by permitting a sufficient efflux of gold from its own immense holdings, the Genoa system continued to function. But in late 1928 and 1929, the Fed, responding to domestic fears about a possible stock-market bubble, kept raising interest rates to levels not seen since the deflationary disaster of 1920-21. And sure enough, a 6.5% discount rate (just shy of the calamitous 7% rate set in 1920) reversed the flow of gold out of the US, and soon the US was accumulating gold almost as rapidly as the insane Bank of France was. This was exactly the scenario against which Hawtrey and Cassel had been warning since 1919. They saw it happening, and watched in horror while their warnings were disregarded as virtually the whole world plunged blindly into a deflationary abyss. Keynes had some inkling of what was going on – he was an old friend and admirer of Hawtrey and had considerable regard for Cassel – but, for reasons I don’t really understand, Keynes was intent on explaining the downturn in terms of his own evolving theoretical vision of how the economy works, even though just about everything that was happening had already been foreseen by Hawtrey and Cassel. More than a quarter of a century after the fact, and after the Keynesian Revolution in macroeconomics was well established, along came Friedman, woefully ignorant of pre-Keynesian monetary theory, but determined to show that the Keynesian explanation for the Great Depression was wrong and unnecessary. So Friedman came up with his own explanation of the Great Depression that did not even begin until December 1930 when the Fed allowed the Bank of United States to fail, triggering, in Friedman’s telling, a wave of bank failures that caused the US money supply to decline by a third by 1933. Rather than see the Great Depression as a global phenomenon caused by a massive increase in the world’s monetary demand for gold, Friedman portrayed it as a largely domestic phenomenon, though somehow linked to contemporaneous downturns elsewhere, for which the primary explanation was the Fed’s passivity in the face of contagious bank failures. Friedman, mistaking the epiphenomenon for the phenomenon itself, ignorantly disregarded the monetary theory of the Great Depression that had already been worked out by Hawtrey and Cassel and substituted in its place a simplistic, dumbed-down version of the quantity theory. So Friedman reinvented the wheel, but did a really miserable job of it. A. C. Pigou, Alfred Marshall’s student and successor at Cambridge, was a brilliant and prolific economic theorist in his own right. In his modesty and reverence for his teacher, Pigou was given to say “It’s all in Marshall.” When it comes to explaining the Great Depression, one might say as well “it’s all in Hawtrey.” So I agree that Delong is totally justified in criticizing Friedman and his followers for giving such a silly explanation of the Great Depression, as if it were, for all intents and purposes, made in the US, and as if the Great Depression didn’t really start until 1931. But the problem with Friedman is not, as Delong suggests, that he distracted us from the superior insights of Keynes and Minsky into the causes of the Great Depression. The problem is that Friedman botched the monetary theory, even though the monetary theory had already been worked out for him if only he had bothered to read it. But Friedman’s interest in the history of monetary theory did not extend very far, if at all, beyond an overrated book by his teacher Lloyd Mints A History of Banking Theory. As for whether fiscal expansion called for by Keynes was necessary to end the Great Depression, we do know that the key factor explaining recovery from the Great Depression was leaving the gold standard. And the most important example of the importance of leaving the gold standard is the remarkable explosion of output in the US beginning in April 1933 (surely before expansionary fiscal policy could take effect) following the suspension of the gold standard by FDR and an effective 40% devaluation of the dollar in terms of gold. Between April and July 1933, industrial production in the US increased by 70%, stock prices nearly doubled, employment rose by 25%, while wholesale prices rose by 14%. All that is directly attributable to FDR’s decision to take the US off gold, and devalue the dollar (see here). Unfortunately, in July 1933, FDR snatched defeat from the jaws of victory (or depression from the jaws of recovery) by starting the National Recovery Administration, whose stated goal was (OMG!) to raise prices by cartelizing industries and restricting output, while imposing a 30% increase in nominal wages. That was enough to bring the recovery to a virtual standstill, prolonging the Great Depression for years. I don’t say that the fiscal expansion under FDR had no stimulative effect in the Great Depression or that the fiscal expansion under Obama in the Little Depression had no stimulative effect, but you can’t prove that monetary policy is useless just by reminding us that Friedman liked to assume (as if it were a fact) that the demand for money is highly insensitive to changes in the rate of interest. The difference between the rapid recovery from the Great Depression when countries left the gold standard and the weak recovery from the Little Depression is that leaving the gold standard had an immediate effect on price-level expectations, while monetary expansion during the Little Depression was undertaken with explicit assurances by the monetary authorities that the 2% inflation target – in the upper direction, at any rate — was, and would forever more remain, sacred and inviolable. In his latest blog post Paul Krugman drew my attention to Keynes’s essay The Great Slump of 1930. In describing the enormity of the 1930 slump, Keynes properly compared the severity of the 1930 slump with the 1920-21 episode, noting that the price decline in 1920-21 was of a similar magnitude to that of 1930. James Grant, in his book on the Greatest Depression, argues that the Greatest Depression was so outstanding, because, in contrast to the Great Depression, there was no attempt by the government in 1920-21 to cushion the blow. Instead, the powers that be just stood back and let the devil take the hindmost. Keynes had a different take on the difference between the Greatest Depression and the Great Depression: First of all, the extreme violence of the slump is to be noticed. In the three leading industrial countries of the world—the United States, Great Britain, and Germany—10,000,000 workers stand idle. There is scarcely an important industry anywhere earning enough profit to make it expand—which is the test of progress. At the same time, in the countries of primary production the output of mining and of agriculture is selling, in the case of almost every important commodity, at a price which, for many or for the majority of producers, does not cover its cost. In 1921, when prices fell as heavily, the fall was from a boom level at which producers were making abnormal profits; and there is no example in modern history of so great and rapid a fall of prices from a normal figure as has occurred in the past year. Hence the magnitude of the catastrophe. In diagnosing what went wrong in the Great Depression, Keynes largely, though not entirely, missed the most important cause of the catastrophe, the appreciation of gold caused by the attempt to restore an international gold standard without a means by which to control the monetary demand for gold of the world’s central banks — most notoriously, the insane Bank of France. Keynes should have paid more attention to Hawtrey and Cassel than he did. But Keynes was absolutely on target in explaining why the world more easily absorbed and recovered from a 40% deflation in 1920-21 than it was able to do in 1929-33. Commenter TravisV kindly referred me to a review article by David Frum in the current issue of the Atlantic Monthly of The Delugeby Adam Tooze, an economic history of the First World War, its aftermath, and the rise of America as the first global superpower since the Roman Empire.

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_{t,u}$ for some vertex $u\in S$. Then there is a subset $S_t\subset S$ with $\rm{vol}(S_t)$$\geq\varsigma/2$ for which a sweep over $\hat{\rho}_{t,u}$ for any vertex $u\in S_t$ with 1. $t={\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$ and 2. $\Phi_{\varsigma}(\hat{\rho}_{t,u})^2 \leq 4/t\log(2)$\[assumption:sweepcheeg\] finds a set with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. Let $u$ be a vertex in $S_t$ as described in the theorem statement. Using the inequalities (\[eq:approxineq\]), we can bound the local Cheeger ratio by a sweep over $\hat{\rho}_{t,u}$: $$e^{-t{\Phi^*(S)}} \leq \frac{2}{1-\epsilon}(\sqrt{\varsigma}e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4}+\epsilon s)$$ which implies $$e^{-t{\Phi^*(S)}} \leq e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4} \Big(\frac{2\sqrt{\varsigma}}{1-\epsilon} + \epsilon s e^{t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4}\Big),$$ and by the assumption \[assumption:sweepcheeg\], we have $$\begin{aligned} e^{-t{\Phi^*(S)}} &\leq e^{-t\Phi_{\varsigma}(\hat{\rho}_{t,u})^2/4} \Big(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s\Big)\\ {\Phi^*(S)}&\geq \frac{\Phi_{\varsigma}(\hat{\rho}_{t,u})^2}{4} - \frac{\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}{t}.\end{aligned}$$ Let $x=\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)$. Then, $$\Phi_{\varsigma}(\rho_{t,f_S})^2 \leq 4{\Phi^*(S)}+ 4x/t.$$ Since ${\Phi^*(S)}\leq \Phi(S) \leq \phi$ and $t = \phi^{-1}x$, it follows that $\Phi_{\varsigma}(\hat{\rho}_{t,u}) \leq \sqrt{8\phi}$. In particular, a sweep over $\hat{\rho}_{t,u}$ finds a cut with Cheeger ratio $O(\sqrt{\phi})$ as long as $u$ is contained in $S_t$. We are now prepared to give our algorithm for finding cuts locally with heat kernel pagerank. The algorithm takes as input a starting vertex $u$, a desired volume $\varsigma$ for the cut set, and a target Cheeger ratio $\phi$ for the cut set. Then, to find a set achieving a minimum $\varsigma$-local Cheeger ratio, we perform a sweep over an approximate heat kernel pagerank vector with the starting vertex as a seed. input: a graph $G$, a vertex $u$, target cluster size $s$, target cluster volume $\varsigma \leq {\textmd{vol}}(G)/4$, target Cheeger ratio $\phi$, error parameter $\epsilon$.\ output: a set $T$ with $\varsigma/2 \leq {\textmd{vol}}(T) \leq 2\varsigma$, $\Phi(T) \leq \sqrt{8\phi}$.\ $t \gets {\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$ $\hat{\rho} \gets {\texttt{ApproxHKPRseed($G,t,u,\epsilon$)}}$\[line:hkpr\] sort the vertices of $G$ in the support of $\hat{\rho}$ according to the ranking $\hat{\rho}[v]/d_{v}$\[line:sort\] \[line:sweep\] $S_j = \bigcup_{i\leq j}v_i$ \[line:volume\] output `NO CUT FOUND`, break \[line:checks\] output $S_j$ output `NO CUT FOUND` [\[thm:localpart\]]{} Let $G$ be a graph which contains a subset $S$ of volume at most $\rm{vol}(G)/4$ and Cheeger ratio bounded by $\phi$. Further, assume that $u$ is contained in the set $S_t\subseteq S$ as defined in Theorem \[thm:main\]. Then [`ClusterHKPR(G,u,s,\varsigma,\phi,\epsilon)`]{}outputs a cutset $T$ with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. The running time is the same as that of [`ApproxHKPRseed`]{}. Since it is given that $u\in S_t$ for $t={\phi^{-1}\log(\frac{2\sqrt{\varsigma}}{1-\epsilon} + 2\epsilon s)}$, and by the assumptions on $G$ and $S$, Theorem \[thm:main\] states that a sweep over the approximate heat kernel pagerank vector $\hat{\rho}$ will find a set with $\varsigma$-local Cheeger ratio at most $\sqrt{8\phi}$. The checks performed in line \[line:checks\] of the algorithm discover such a set. The computational work reduces to the main procedures of computing the heat kernel pagerank vector in line \[line:hkpr\] and performing a sweep over the vector in line \[line:sweep\]. Performing a sweep involves sorting the support of the vector (line \[line:sort\]) and calculating the conductance of segments. From the guarantees of an $\epsilon$-approximate heat kernel pagerank vector, any vertex with average probability less than $\epsilon$ will be excluded from the support. Then the volume of a vector $\hat{\rho}$ output in line \[line:hkpr\] is $O(\epsilon^{-1})$, and performing a sweep over $\hat{\rho}$ can be done in $O(\epsilon^{-1}\log(\epsilon^{-1}))$ time. The algorithm is therefore dominated by the time to compute a heat kernel pagerank vector, and the total running time is ${O\big(\frac{\log(\epsilon^{-1})\log n}{\epsilon^3\log\log(\epsilon^{-1})}\big)}$. Ranking Vertices with Approximate Heat Kernel Pagerank {#sec:rankings} ====================================================== The backbone procedure of the local clustering algorithm is the sweep: ranking the vertices of the graph according to their approximate heat kernel pagerank values, and then testing the quality of the cluster obtained by adding vertices one at a time in the order of this ranking. To this end, in this section we compare the rankings of vertices obtained using exact heat kernel pagerank vectors with approximate heat kernel pagerank vectors. Specifically, we consider how accuracy changes as the upper bound of random walk lengths, $K$, vary. In the following experiments, we approximate heat kernel pagerank vectors by sampling random walks of length $\min\{k, K\}$, where $k$ is chosen with probability $p_k = e^{-t}\frac{t^k}{k!}$. We test the values computed with different values of $K$. Since the expected value of a random walk length $k$ chosen with probability $p_k = e^{-t}\frac{t^k}{k!}$ is $t$, we set $K$ to range from $1$ to approximately $t$ for a specified value of $t$. In each trial, for a given graph, seed vertex, and value of $t$, we compute an exact heat kernel pagerank vector $\rho_{t,u}$ and an approximate heat kernel pagerank vector $\hat{\rho}_{t,u}$ using [`ApproxHKPRseed`]{} but limiting the length of random walks to $K$ for various $K$ as described above. We then measure how similar the vectors are in two ways. First, we compare the vector values computed. Second, we compare the rankings obtained with each vector. The following are the measures used: 1. *Comparing vector values.* We measure the error of the approximate vector $\hat{\rho}_{t,u}$ by examining the values computed for each vertex and comparing to an exact vector $\rho_{t,u}$. We use the following measures: - **Average $L_1$ error**: The average absolute error over all vertices of the graph, $$\label{eq:measure-l1err} \mbox{average $L_1$ error } := \frac{1}{n}\sum_{i=1}^n |\rho_{t,u}(v_i)-\hat{\rho}_{t,u}(v_i)|.$$ - **$\epsilon$-error**: The accumulated error in excess of an $\epsilon$-approximation (see Definition \[def:eps-approx\]), $$\begin{aligned} \mbox{$\epsilon$-error } := &\sum_{v\in V, \hat{\

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While Taylor has now broken records in the pop genre, Little Big Town insists she hasn’t completely parted with her country roots. “She’s a Nashville songwriter,” Little Big Town‘s Karen Fairchild told USA Today. “When you write a song like “Better Man” top to bottom on your own with your acoustic guitar, that’s Nashville. She’s a storyteller. She loves country music. Her last record was more poppy but who knows? Taylor can do anything she wants to. And she will forever be a Nashville girl.”Q: How to extract text data in a table created in a docx document I would like to extract text from docx document, I come up with a script extracting text from docx document but I noticed that some document have table and the script do not work on them, How can I improve the above script : import glob import os import docx with open('your_file.txt', 'w') as f: for directory in glob.glob('fi*'): for filename in glob.glob(os.path.join(directory, "*")): if filename.endswith((".docx", ".doc")): document = docx.Document(filename) for paragraph in document.paragraphs: if paragraph.text: #docText.append(paragraph.text) f.write("%s\n" % paragraph.text) docx with table A: Try using python-docx module instead pip install python-docx import docx doc = docx.Document("document.docx") for table in doc.tables: for row in table.rows: for cell in row.cells: print(cell.text) Promoting Health and Behavioral Health Equity in California. Behavioral health disparities are not usually considered part of the same system of health disparities. However, the California Department of Public Health focused its health equity strategies on reducing behavioral health disparities through its California Statewide Plan to Promote Health and Mental Health Equity. This statewide plan was developed through a community-wide stakeholder engagement and outreach process. In addition, the California Reducing Disparities Project is a prevention and early intervention effort to reduce mental health disparities in underserved populations. This strategic plan represents the voice of several racial/ethnic communities, such as African American, Asian and Pacific Islander, Latino, Native American, as well as lesbian, gay, bisexual, transgender, and queer and questioning communities in California, through 5 strategic planning workgroups. The workgroups were composed of a broad range of stakeholders, including community leaders, mental health care providers, consumer and family members, individuals with lived experience, and academia. This case example highlights the various efforts of California's Office of Health Equity in eliminating behavioral health disparities and promoting mental health equity, as well as discusses the unique statutory and regulatory role of the Office of Health Equity's deputy director.@import "~styles/variables"; thead { font-size: 14px; letter-spacing: 0.2px; color: $chef-primary-dark; } th { text-align: left; padding: 0px; } tbody > .detail-row { padding-top: 0px; padding-bottom: 15px; } chef-table-new { .controls { text-align: right; } a { cursor: pointer; text-decoration: underline; } } chef-loading-spinner { display: block; margin: 100px auto; width: 100px; z-index: 199; } Q: Laravel 7.0 MySQL SQLSTATE[HY000]: General error: 1824 Failed to open the referenced table System Info: OS: Ubuntu 19.10 Laravel Version: 7.0 PHP Version: 7.3.11-0ubuntu0.19.10.4 MySQL Version: mysql Ver 8.0.19-0ubuntu0.19.10.3 for Linux on x86_64 ((Ubuntu)) I am building a small Laravel application and am having an issue with MySQL and relationships. When I try to run my migrations, this is the error I get: SQLSTATE[HY000]: General error: 1824 Failed to open the referenced table 'customers_table' (SQL: alter table `customer_contacts` add constraint `customer_contacts_customer_id_foreign` foreign key (`customer_id`) references `customers_table` (`id`)) And these are the two migration files in question. customer table and migration: <?php use Illuminate\Database\Migrations\Migration; use Illuminate\Database\Schema\Blueprint; use Illuminate\Support\Facades\Schema; class CreateCustomersTable extends Migration { /** * Run the migrations. * * @return void */ public function up() { Schema::create('customers', function (Blueprint $table) { $table->id(); $table->string('company_name', 50); $table->string('phone_number', 20)->nullable(); $table->string('fax_number', 20)->nullable(); $table->string('address_line_1', 75)->nullable(); $table->string('address_line_2', 75)->nullable(); $table->string('city', 75)->nullable(); $table->string('state', 30)->nullable(); $table->string('zip', 11)->nullable(); $table->string('industry', 100)->nullable(); $table->text('notes')->nullable(); $table->timestamps(); }); } /** * Reverse the migrations. * * @return void */ public function down() { Schema::dropIfExists('customers'); } } And the customer_contacts table and migration: <?php use Illuminate\Database\Migrations\Migration; use Illuminate\Database\Schema\Blueprint; use Illuminate\Support\Facades\Schema; class CreateCustomerContactsTable extends Migration { /** * Run the migrations. * * @return void */ public function up() { Schema::create('customer_contacts', function (Blueprint $table) { $table->id(); $table->foreignId('customer_id')->constrained('customers_table'); $table->string('name', 50); $table->string('title', 50); $table->string('project', 50); $table->string('email', 50); $table->string('mobile_phone', 20); $table->string('work_phone', 20); $table->timestamps(); }); } /** * Reverse the migrations. * * @return void */ public function down() { Schema::dropIfExists('customer_contacts'); } } And this is the relevant section from my database.php file: ... 'mysql' => [ 'driver' => 'mysql', 'url' => env('DATABASE_URL'), 'host' => env('DB_HOST', '127.0.0.1'), 'port' => env('DB_PORT', '3306'), 'database' => env('DB_DATABASE', 'forge'), 'username' => env('DB_USERNAME', 'forge'), 'password' => env('DB_PASSWORD', ''), 'unix_socket' => env('DB_SOCKET', ''), 'charset' => 'utf8mb4', 'collation' => 'utf8mb4_unicode_ci', 'prefix' => '', 'prefix_indexes' => true, 'strict' => true, 'engine' => 'InnoDB', 'options' => extension_loaded('pdo_mysql') ? array_filter([ PDO::MYSQL_ATTR_SSL_CA => env('MYSQL_ATTR_SSL_CA'), ]) : [], ], ... I tried changing my database to SQLite to see if I get the same error and I do not, only MySQL creates this error. A: Use $table->foreignId('customer_id')->constrained('customers') Instead of $table->foreignId('customer_id')->constrained('customers_table'); Cheers Dave – the short answer is I don’t I fire everything up, open up the aperture and then retire indoors to the study to drive everything from the warm.

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"Fuck you, too, David. I'm out of here." Sasha was sick of all of them. She'd seen where the bullets were buried and that was all she needed to know. She turned on her heel and started up the hill, breaking into a jog. "Sasha!" Julian called after her. "Catch you later?" "Forget it!" Sasha called back, charging up the hill. ## CHAPTER 14 ■ ## Julian Browne Julian's mother entered the room with a tray holding a bowl of popcorn and root beer floats. She had gone to a lot of trouble, but all he could think about was Sasha. It was already past eight o'clock at night, and Sasha hadn't been home since they buried the gun and bullets. He'd been watching the house, and her room was completely dark. The only lights on were in Bonnie and Clyde's suite and the family room downstairs, which they kept on when Sasha wasn't home. Julian didn't know where she was, and it was driving him crazy. "Movie night!" his mother said, setting down the tray. "How much fun is this?" "Fun." Julian smiled, hoping it looked convincing. "Real butter and everything?" "Nothing but the best for my baby!" His mother put a napkin in front of him, then a root beer float with a special long spoon. His parents used to entertain all the time, and his mother had shrimp forks, mother-of-pearl caviar spoons, and cake knives. She even had special ice cream dishes, gravy boats, soup tureens, and ramekins; Julian knew the names because she took the time to educate him. Now the only person she was entertaining was him. "I just love that we get to spend this time together, truly quality time." "Right." Julian glanced out the window, keeping an eye on Sasha's house. Their family room was cavernous with brown leather sectionals arranged opposite the fireplace and entertainment center, and on the left side of the room, they had huge Palladian windows. It gave Julian a great view of the street, and from this angle, Sasha's house. The light over her front door was on. He sensed she was punishing him for what happened with Allie. "Have some root beer float. It's going to melt." "Good point." Julian picked up the spoon and slurped some root beer float, which tasted absolutely delicious. "This is perfect, Mom. Thanks." "I love that you still drink it with the spoon. You used to do that when you were little." "This spoon seemed bigger then." "I'm sure." His mother grinned broadly, so excited on these weeknights, when it was _her night_ as opposed to _his father's night_ , since Julian went to his dad's house on alternating Tuesdays and Thursdays, depending on if he had been there the weekend. His mother always tried to plan something special for them, which they had never done when his father lived at home. He secretly wondered if she felt she had to, in order to win him over in the battle of who he liked better, mommy versus daddy. Of course she won hands-down, but he could never convince her of that and he understood why. His father offered motorboats, blondes, and no adult supervision. Because his father wasn't an adult. "Which movie do you want to watch first?" His mother held up the two VHS tapes, her pick, _You've Got Mail,_ and his pick, _The Big Lebowski_. "We can watch yours first, Mom." "No, we can do yours." "Please, you love chick flicks." Julian glanced out the window, but the Barrow house was still dark and quiet. One of their neighbors was walking his malamute, but nobody else was on the street. "No, we watched mine first last time, remember? I love a double feature!" "What's a double feature?" "Oh my, I'm dating myself. Oh well, somebody has to these days!" His mother laughed as she crossed the room, slid the tape into the VHS player, and picked up the remote, hitting a few buttons to get the tape running. She eyed _The Big Lebowski_ box. "What's this about again?" "It's great, I love it." "Wait, you saw it already?" "Yeah, I told you at the store." "I didn't hear you. Don't tell me my hearing's going now, too." "I saw it with Dad." Julian didn't add that his father hadn't seen the movie with him, just dropped him off. "It doesn't matter. I want to see it again." "I didn't want you to have to sit through something you saw already." "But I love it. I want to." "Okay." His mother returned her attention to the movie, which was starting. "So is that man the big Lebowski? He wears a bathrobe to the grocery store?" "Yeah, he's a stoner." His mother frowned. "You mean he smokes dope?" "Weed." "We called it dope, in my day." "People call it weed now." Julian didn't explain that his father called it weed, even though he was from the same day. Nor did he tell her that his father smoked weed on the boat. "But _you_ would never smoke dope, er, weed." His mother shot him a look. "No, I wouldn't." Julian didn't say that he'd tried weed for the first time when his father gave him some on a trip to Cape May. Julian had liked smoking with his dad and the blonde _du jour_. His father let him have beer, too, but Julian took it easy because beer made him fart, which would not be cool. "Don't even experiment with it, okay?" His mother sat down on the couch. "They tell you that in school, right?" "Yeah, in D.A.R.E., since middle school." Julian didn't add that the weed-and-beer combination made him throw up over the side of the boat. His father had laughed, and the blonde hadn't known what to do, though his mom would have brought him a ginger ale. His mother frowned at the TV screen. "Does this glorify drug use?" "It's a comedy; he's funny." Julian was so preoccupied he couldn't think straight. Sasha still wasn't home. She dated seniors like Jake Myers, Malcolm Hobb-Jacobs, and Zachary Pearlstein, major competition. Julian knew their cars, so when one of them dropped her off, he would know who. "Jeff Bridges used to be so handsome! He really let himself go for this role!" "He drinks White Russians. That's his thing. He drinks them all the time. He calls them his 'beverage.'" Julian didn't remind his mother that she had drunk plenty in her entertaining days, and she fell silent, watching the movie with growing disapproval. "There are a lot of f-words in this movie, honey." His mother shook her head, clucking. "Why would your father take you to a movie that's so inappropriate?" "I asked." "It's not on you, it's on him. What's it rated?" "Don't worry about it, Mom." Julian rolled his eyes, restless. This was going to end up with his mother calling her lawyer, then her lawyer calling his father's lawyer, who would talk to his father, which sucked. The movie went on without Julian seeing it, thinking of Sasha. "Oh no, who are those guys?" "Bad guys." "Why are they hurting him?" "They have him mixed up with another Lebowski. He's Jeffrey Lebowski, the Dude. They think he's a millionaire." "Wait, are they _peeing on the rug_?" His mother threw up her manicured hands. "Julian, how can you like this movie? It doesn't make any sense." "Let's watch yours then, okay?" Julian couldn't enjoy it anyway. Where the hell was Sasha? Who was she with? Was she having sex with one of those seniors? Seniors got it all the time, didn't they? They expected it! It made Julian crazy because he had loved her for forever. "You mean stop watching it? Are you sure you don't mind?" His mother pouted prettily, like the cheerleader she'd been, and Julian realized that beautiful women always got what they wanted. Sasha sure did. "I saw it already. See, it turned out fine." "You sure?" "Please put on your chick flick, Mom." "Don't call it a chick flick. It's a love story. Men can enjoy love stories, don't you think?" "Yes," Julian said, ironically in the circumstances. Suddenly he noticed a car pulling up in front of Sasha's house. Zachary Pearlstein's red BMW 325. "Here we go! Oh, I love Tom Hanks. Isn't he just the best? I think he's so cute

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a catalog. When it came, no lie, my kids fought daily over who would get to read it on the bus, and how long each was allowed to have it, and whether or not the others were taking good care of it during their turns. Even the neighbor boys were in awe of this treasure. It didn't take me long to realize what I needed to do. I needed to call LEGO. After I explained that just one was not going to do it for us, I signed ALL THREE of my boys up to receive their very OWN catalog. They have anxiously anticipated them from that moment onward. Like I said, they "read" them on the bus. They read them in the car. They read them while we're waiting--just about anywhere. They read them in their bedrooms, and at the kitchen counter. They read them in the bathroom and even under blankets with a flashlight. Yes, boys, I know about that. So order. It's FREE! The boys in your life will think you rock. And that doesn't happen nearly enough! We've not tried this one, but LEGO also has a program called BrickMaster. It costs $39.99 and comes with six BrickMaster Edition LEGO magazines (one every two months), Six surprise LEGO toys (mailed out one every two months), two LEGO Shop at Home Coupons, and a free LEGOLAND California Admission ticket. If any of you have tried this, I'd love to hear your thoughts on it! 11 comments: You also need to sign the boys up for the Lego and Bionicle MAGAZINES! My son thinks they are the greatest things ever produced, and they both are completely free - he has been getting them for a few years now! Have fun!! Augh -- I tried to do it, and saw that it asked about age ranges. I didn't read and just assumed they were asking the age of my kids. Oops -- must have been asking my age, because now it won't let me ask for a catalog. D'oh! We signed up for the magazine a few months ago and my son kept asking whether or not the magazine had come in the mail and if it didn't he thought I ought to call them and remind them or see what was happening - he was so eager to get it. And then - just b/c of the timing of our subscription we got 2 or 3 in a very short time - so he was happy. All three of my kids loved LEGOS when they were younger. And LEGO land was the ultimate play place for them! Now that they're older, I'm just waiting for them to have kids so I can start stocking up on LEGOS again! We love Lego mags at our house! In fact, I have to hide them so they don't discover them until AFTER homework is done. I've also been thinking about the Brickmaster thing. My guys have told me it would be "hard to share," so I'm looking at 2 - which means $80 - not that it doesn't seem worth it. I'm thinking Brickmaster may be birthday presents in 2009. "Let's raise our children up in prayer. . . . . . as we raise them up to serve our God!"Here, you'll find food for thought, helpful tips, DIY tricks, and stories from everyday life, all posted with the hope of encouraging and strengthening families in every aspect of life. Followers Great Resources Product ReviewsDo you have a family friendly product you think my readers would like? I give honest and informative reviews of family friendly products. Please feel free to drop me an email and we can discuss the possiblity of sharing your product with my readers! Be sure to include "review" in the subject line.5 tablespoons (1/3rd cup) bleach per gallon of water OR OR 4 teaspoons bleach per quart of water Follow manufacturer’s instructions for application and proper ventilation. Check to ensure the product is not past its expiration date. Never mix household bleach with ammonia or any other cleanser. Unexpired household bleach will be effective against coronaviruses when properly diluted.Cannabis industry exploding with growth here, says top pot exec The cannabis business is growing like a weed, even as pot stocks see wild swings. With Smoke Wallin, Vertical Companies, CNBC's Scott Wapner and the Fast Money traders, Pete Najarian, Tim Seymour, Karen Finerman and Guy Adami.Shifts of system performance and microbial community structure in a constructed wetland after exposing silver nanoparticles. The increasing utilization of silver nanoparticles (Ag NPs) in industry and commerce inevitably raises its release into wastewater. In this work, effects of Ag NPs on system performance and microbial community along the way of a vertical flow constructed wetland (VFCW) were investigated, along with the removal and fate of Ag NPs within the system. Results showed that the performance of control wetland kept stable during the experimental period, and the top substrate layer (soil layer) of wetland could remove most of pollutants in the influent. The study also suggested that addition of Ag NPs did not significantly affect organic matters removal. However, adverse effects were observed on the nitrogen and phosphorus removal. Removal efficiencies of TN, NH4+-N and TP approximately obviously reduced by approximately 10.10%, 8.42% and 28.35% respectively in contrast to before dosing after exposing 100 μg/L Ag NPs for 94 d, while the no dosing wetland with the stable performance. It was found that Ag NPs accumulated in the upper soil layer more than in the lower soil layer, and Ag NPs could enter into the plant tissues. After continuous input of Ag NPs, removal efficiency of Ag NPs was measured as 95.72%, which showed that the CW could effectively remove Ag NPs from the wastewater. The high-throughput sequencing results revealed that Ag NPs caused the shifts in microbial community structures and changed the relative abundances of key functional bacteria, which finally resulted in a lower efficiency of biological nitrogen and phosphorus removal.John Vorster Square in central Johannesburg is a building as cold and formidable as the man it was named after: South Africa's prime minister from 1966 to 1978. Created as a detention centre for mainly political prisoners, the forbidding grey-and-blue, 10-storey cement building, now known as the Johannesburg Central Police Station, was described in 1971 as the "last word in security" by the liberal South African newspaper, the Rand Daily Mail. In his book, Timol: A Quest for Justice, Imtiaz Cajee, nephew of anti-apartheid activist Ahmed Timol, wrote of the "paranoia of its turnstiles clamping together like metal teeth". To Cajee, whose uncle died at John Vorster Square, it was "the ultimate symbol of the bureaucratisation of fear and horror under apartheid". Former Minister of Health and of Public Enterprises Barbara Hogan, who - as the first South African woman to be found guilty of high treason - was detained there, described it as an "iconic institution" that symbolised "the reign of the mad forces". The ninth and 10th floors of the building were where the headquarters of the Security Branch was located. They could be accessed by two special lifts that ran straight from the basement to the headquarters. The Security Branch offices contained special soundproof rooms. Direct-line telephones were connected to the Security Branch headquarters in the capital, Pretoria. The detainee cells were on the lower floors. The Johannesburg Central Police Station, formerly known as John Vorster Square, was the site of the death of political activist and detainee Ahmed Timol [GULSHAN KHAN/AFP] Detention without trial John Vorster Square was one of the architectural symbols of apartheid. But the real pillars of apartheid were the draconian security legislation passed to segregate and intimidate. One of the most chilling laws passed during Vorster's leadership was the Terrorism Act of 1967 which allowed the police to detain indefinitely and in solitary confinement anyone suspected of "terrorism" - defined as anyone who might "endanger the maintenance of law and order" - or having information about terrorism. No court could intervene, and no one had access to the detainees. According to George Bizos, a celebrated human rights lawyer who represented many families of apartheid-era detainees, John Vorster's name became associated with detention without trial. "The name John Vorster inspired fears among detainees," said Bizos. One of the most common methods of torture used in John Vorster Square was "standing torture", during which detainees were prevented from sleeping or sitting down for many hours on end. At least 73 political activists are thought to have died in South African police detention between 1963 and 1990 - eight of them during or as a result of their detention at John Vorster Square. In spite of the work of the Truth and Reconciliation Commission (TRC) between 1996 and 1999, most of these cases remained shrouded in secrecy. That was until inquests into the deaths began to be reopened in 2017, in large part thanks to the tireless efforts of Imtiaz Cajee. "Imtiaz has been waging a long campaign for truth and justice," said Howard Varney, lawyer for the Timol family. The first inquest to be reopened was that of Ahmed Timol, the first activist who died at John Vorster Square. Ahmed Timol Born in 1941, Ahmed Timol, who was of Indian heritage

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they are moot, irrelevant, or without merit. To reflect the foregoing, Decision will be entered under Rule 155. Beta (20-28 Hz) and delta (0.3-3 Hz) EEGs oscillate reciprocally across NREM and REM sleep. Across-night oscillations of beta (20-28 Hz) and delta (0.3-3 Hz) electroencephalograms (EEGs) were examined with spectral analysis in 10 normal young adult subjects (Ss). In each S, power densities of beta were found to oscillate reciprocally with delta power density across both nonrapid eye movement (NREM) and rapid eye movement (REM) sleep. Linear correlation coefficients between log power density of delta vs. beta were significant (p less than 0.0001) for each S. An incidental observation was that beta power within REM was reliably lower in epochs with more eye movement activity. The reciprocal relationship between beta and delta holds implications for sleep physiology and supplements our earlier finding that sigma (12-15 Hz) oscillates reciprocally with delta within NREM sleep. These descriptions of the continuously varying EEG across sleep provide information not available when EEG measures are tabulated by discrete NREM periods and REM periods.As the legislation matures and more directives are formulated, more issues will undoubtedly come to light. To the credit of the office of the Information Regulator, there is a commitment to adopt privacy best practices from around the world. This should provide a solid basis from which to move forward with efforts to protect personal information in South Africa. The practical implications of PoPIA certainly needs considering. Our PoPIA Team has put together answers to a few of the questions being asked on PoPIA forums. How will POPIA protect my personal information collected by the security guards when visiting a complex/residential building? All responsible parties who collect PI for security reasons must ensure the prevention of loss, damage or unlawful processing of PI given for this purpose. In other words, if the PI you have given to gain access to a building is lost, processed unlawfully by another party or damaged in any way that would constitute a breach and as the data subject you would have recourse to the regulator. Does government get held to the same standard as private sector in the event of a breach? Yes, indeed. POPIA applies to all public institutions except for PI processed during a criminal investigation or investigation of any activities related to the financing of terrorism or money laundering. The exception also applies in cases considered sensitive for national security reasons as well as PI processed by the judiciary and the Cabinet. (See section 6 of POPIA) Would a General Practitioner (GP) need to disclose to all patients that they had a data breach, even if only one patient has been compromised? The GP would only have to disclose to the affected patients, unless the GP is ordered to publicise the breach by the information regulator. Who will be responsible if government departments share citizens’ personal information with companies e.g. sharing with SANRAL? I assume this question relates to SANRAL and e-tolling in South Africa. The lawfulness of e-tolling is being challenged by OUTA and is far more complex than the processing of PI. Exactly how sharing of PI across government agencies and different levels of government (i.e. municipal, provincial and national) will apply, I would suggest, will only be known once the Act is in force, regulation has been published and case law exists. The Act does specifically allow for the sharing of PI from private organisations with the South African Revenue Service. How are employees of companies affected by this law if they have access to client information on their mobile devices? Any personal information belonging to clients and stored on mobile devices must meet the security safeguards of prevention of loss, damage or unlawful processing. In practical terms, encryption of all mobile devices is the reasonable control to meet the minimum standards. How would an individual, like a family GP, be ‘punished’ for a data breach? Contravention of POPIA in South Africa will be a criminal offence. Any GP contravening the Act will face administrative penalties (fines) and/ or a prison sentence not exceeding 10 years. See chapter 11, sections 107 and 109 of POPIA. What are the POPIA directives for IT and processing environments? In terms of POPIA and the definition of processing, which includes the collection, storage, retrieval and dissemination of PI for lawful processing, any IT service provider would be deemed to be operators. The responsible party (that is, for example, GP practices) must ensure that all operators, including IT service providers, meet the minimum-security safeguards as contained in condition 7 of POPIA. Like this: Related Pétanque NXT We partner with companies who want to understand and integrate the new 4IR–driven possibilities to reduce cost, improve how they serve their customers and ensure their leadership position in the new business landscape.Utility Planet is the official blog for the column of the same name in The Spectrum Monitor. It replaces Utility World in the discontinued Monitoring Times magazine. Utilities are all VLF/LF/MF/HF (and sometimes low-band VHF) radio communications except broadcasting, CB, and non-emergency amateur. If you understood the last sentence, you know enough to read this blog. Friday, July 28, 2017 More broadcasters are making use of the 9400 kHz frequency from Space Line in Bulgaria. If you have ever considered producing your own radio program, either digital text or traditional voice, contact Space Line via spaceline.bg (I think Saturday 1630-1700 UTC is available!), or Radio Miami International via wrmi.net. (I do not work for or derive income from either transmission company.) This weekend, most of Shortwave Radiogram is in our usual MFSK32 mode, with five images. If reception is difficult, there is also one brief item from Radio Prague in Olivia 64-2000. Here is the lineup for Shortwave Radiogram, program 6, 29-30 July 2017, all in MFSK32 except where noted: The Mighty KBC transmits to Europe Saturdays at 1500-1600 UTC on 9400 kHz (via Bulgaria), with the minute of MFSK at about 1530 UTC (if you are outside of Europe, listen via websdr.ewi.utwente.nl:8901/ ).And to North America Sundays at 0000-0200 UTC (Saturday 8-10 pm EDT) on 9925 kHz, via Germany. The minute of MFSK is at about 0130 UTC. Reports to Eric: [email protected] . See also http://www.kbcradio.eu/ and https://www.facebook.com/TheMightyKbc/. Italian Broadcasting Corporation (IBC)For the complete IBC transmission schedule visithttp://ibcradio.webs.com/Five minutes of MFSK32 is at the end of the 30-minute English-language “Shortwave Panorama,” per the schedule below: WEDNESDAY18.55 UTC6070 KHZ TO EUROPE 19.55 UTC1584 KHZ TO EUROPE THURSDAY02.55 UTC1584 KHZ TO EUROPE FRIDAY01.25 UTC9955 KHZ TO CENTRAL/SOUTH AMERICA SATURDAY01.55 UTC 11580 KHZ TO NORTH AMERICA 20.25 UTC1584 KHZ TO SOUTH EUROPE SUNDAY00.55 UTC7730 KHZ TO NORTH AMERICA 10.55 UTC6070 KHZ TO EUROPE Thanks for your reports.I will begin sending replies and QSLs for SWRG program 4 this weekend.And I hope eventually to catch up! I was amazed how well the MFSK64 (240 wpm) performed last week, even under some marginal conditions. You can see videos of reception and decoding via this link: https://twitter.com/SWRadiogram/status/885863588677791746 . It would be tempting to use MFSK64 as our “default” mode, except that there would be enough instances of difficult reception that the number of errors would be unacceptable. Did anyone experience reception bad enough that only the MFSK16 provided a perfect decode? This weekend, let’s hope for bad reception – well, at least somewhere – because we will include some Olivia 64-2000 in show. This is a slow mode, only about 25 wpm. And it makes use of the entire 2000 Hz available to us, so you probably don’t want to use an extremely narrow filter. Also, for best results with Olivia 64-2000, turn the squelch (SQL at the bottom right of Fldigi) off. Here is the lineup for Shortwave Radiogram, program 4, 15-16 July 2017, all in MFSK32 except where noted: The Mighty KBC transmits to Europe Saturdays at 1500-1600 UTC on 9400 kHz (via Bulgaria), with the minute of MFSK at about 1530 UTC (if you are outside of Europe, listen via websdr.ewi.utwente.nl:8901/ ). And to North America Sundays at 0000-0200 UTC (

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education and orientation programs. This should be considered carefully when planning the contents and educational methods for the programs. There are approximately 30 intensive care units (ICUs) in Finland in which over 28,000 patients are cared for annually \[[@B1]\]. It is estimated that by the year 2030 the need for intensive and critical care will grow by 25%, for example, due to the fact that the Finnish population is getting older \[[@B2]\]. Multifactorial reasons increase the need of critical care beds in Finland and also in other countries in Europe. Intensive care unit nurses (ICU nurses) are the largest professional group working in the ICUs. Severely ill patients and families benefit from the attention of highly trained and skilled personnel \[[@B3], [@B4]\]. ICU nurses contribute to patient safety, such as improved patient outcomes, reduced morbidity and mortality, and decreased complications, errors, and overall costs \[[@B5]--[@B10]\]. Competent ICU nurses have a significant impact on ICU patient\'s physiological and psychological outcomes, for example, evidence based nursing interventions and ethical activity. Critical care nursing is an own nursing speciality \[[@B11]\] whereas technology is integrated with psychosocial challenges and ethical conflicts associated with critical illness \[[@B12]\]. Generally, critical care nursing education is a special postqualification education \[[@B13]\] and is described in the European Qualifications Framework for Lifelong Learning as level 6 (of eight) \[[@B14], [@B15]\]. Currently no postqualification education in intensive and critical care nursing leading to a degree exists in Finland. We know that there is a worldwide need for competent nurses \[[@B16]\]. In nursing practice, nurses get to demonstrate on a regular basis clinical competence as well as a sound theoretical knowledge base according to nationally recognized frameworks \[[@B4], [@B17], [@B18]\]. There is a need for valid specific instruments (e.g., for intensive and critical care nursing) for competence evaluation purposes. Competence evaluation can be performed in various ways, for example, using self-assessment, knowledge tests, peer evaluation (colleague), observation (mentor, supervisor), OSCE (objective structured clinical examination), or portfolios. The best way to perform competence evaluation is to combine different evaluation methods. Self-assessment is an essential ability that can be learned and developed during education and nursing career. Intensive and Critical Care Nursing Competence Scale research is scarce. Only three scales (Basic Knowledge Assessment Tool \[BKAT\], Intensive Care Hundred Item Test \[I-HIT\], and multilevelled critical care competency statements) of competence in intensive and critical care nursing are reported in nursing literature \[[@B19]\]. Of these scales, two are knowledge tests (BKAT + I-HIT) while the third one is based on nurses\' self-assessment; however, we are well aware that it has not been properly tested for reliability and validity and is still in its early phases. The need for a basic competence self-assessment scale in intensive and critical care nursing is therefore also evident, for example, for undergraduate education for beginning registered nurses practice standards. The systematic literature review conducted for this study in PubMed and search from critical care nursing organizations over the last ten years found 21 studies or documents of competence in intensive and critical care nursing (see the appendix). As a summary of the literature, competence concept is very multidimensional (e.g., focusing on clinical practice \[nursing process\], ethics, collaboration, leadership, education, and development work) and strongly related to, for example, age, work experience, and frequency of using specific competencies. Competence is studied worldwide (10 documents from Europe, 7 documents from Australia and New Zealand, and 4 documents from USA, Canada, and Brazil); thus, there is lacking systematic competence evaluation research. Evaluation is often performed by self-assessment \[[@B20]--[@B22]\] or knowledge test \[[@B23]\]. ICU nurses\' self-assessed competence was evaluated as ranging from moderate to excellent: from moderate to good (sample consisting of newly registered ICU nurses) \[[@B22]\], good (sample consisting of ICU nurses with varying work experience) \[[@B20]\], and from good to excellent (sample consisting of ICU nurses with varying work experience) \[[@B21]\]. European ICU nurses\' overall knowledge score was 66% of 100 points (min 22, max 91, and SD 12); the main factor that contributed to variance in scores is length of nurses\' intensive care experience. The knowledge category with the lowest score was respiration and ventilation \[[@B23]\]. The purpose of this empirical study was to describe and evaluate the self-assessed basic competence of intensive care unit nurses and related factors using a scale, Intensive and Critical Care Nursing Competence Scale version 1 (ICCN-CS-1) \[[@B11]\]. The related factors were divided into the following areas: (i) age and gender, (ii) education, (iii) work experience, (iv) information retrieval, (v) knowledge test, and (vi) others. The hypothesis was that the basic competence can be explained with these. This empirical study is part of a larger project where the scale was developed \[[@B19]\]. This study was conducted to facilitate establishment of the psychometric properties (reliability and construct validity) of the scale being used \[[@B24]\]. The project from which this study is a part aimed to define competence in intensive and critical care nursing (ICCN), to develop a basic self-assessment based measurement scale for competence evaluation in ICCN, and to describe graduating nursing students\' basic competence in ICCN by seeking reference basis from ICU nurses. ICU nurse is a registered nurse who practises in an ICU and whose nurse education is Bachelor of Health Care, specialist nurse, or nurse. In this ICU nurses basic competence study was used also the experience base of the ICU nurses in data analysis which were not analysed in graduating nursing students\' basic competence study. The students had no experience base enough in ICCN and therefore in data analysis only three bases of four were analysed knowledge, skill, and attitude and value bases. A novel issue in this study is that it highlights the multidimensionality of the concept of competence. Four bases of competence in intensive and critical care nursing were analysed in ICU nurses\' data: knowledge base, skill base, attitude and value base, and experience base \[[@B19]\]. ICCN-CS-1 measures basic competence and it refers to preliminary competence to practice in an ICU. It is comparable to step 1 competencies of the National Competency Framework for Adult Critical Care Nurses \[[@B25]\] and Critical Care Nurse Education Practice Standards \[[@B26]\]. ICCN-CS-1 is useful in planning supervision in preregistration nursing students\' clinical practice and during orientation programmes, for example, to identify learning gaps, define learning goals, and discuss competence in a comprehensive manner. The content of the scale is in line with postgraduate education standards and the competence standards of critical care nurses, also at specialist level. The scale measures the basic competence in intensive and critical care nursing and can be used as a starting point for the transition process from preregistration education to postgraduation education. The scale was developed for intensive and critical care education purposes, for example, for preregistration education and in orientation programmes. The results of this study can be useful in nursing education, especially in basic education and when planning continuous education. In clinical practice the results can also be helpful in professional performance appraisals in ICUs. 2. Materials and Methods {#sec2} ======================== 2.1. Aim {#sec2.1} -------- The aim of the study was to describe and evaluate the self-assessed basic competence of intensive care unit nurses and related factors. The results of this study will help educators, clinicians, and researchers to develop basic nursing education and orientation in the ICUs. 2.2. Research Questions {#sec2.2} ----------------------- The research questions for this study were as follows:What is the level of intensive care unit nurses\' self-assessed basic competence?What are factors related to the basic competence? 2.3. Design {#sec2.3} ----------- A cross-sectional survey design was employed using questionnaires among Finnish ICU nurses in university hospitals. 2.4. Sample/Participants {#sec2.4} ------------------------ Total sampling was used for ICU nurses in five Finnish university hospitals (*n* = 431 participants, response rate 54%). In one of the five university hospitals, a convenience sample of ICU nurses (*n* = 82 participants, response rate 37%) also completed a biological and physiological knowledge test. In 2008, a pilot study had been conducted in one university hospital; this organization was therefore not included in this data gathering in 2010. The final number of hospitals taking part in this study was thus four. 2.5. Data Collection {#sec2.5} -------------------- Data were collected using a questionnaire with the support of contact persons in the ICUs. The instruments used in this study were the Intensive and Critical Care Nursing Competence Scale (ICCN-CS-1) \[[@B24]\] and a knowledge test, the Basic Knowledge Assessment Tool version 7 (=BKAT-7) \[[@B27]\], which was used as the background factor in the convenience sample. Background factors (12) integral to the ICCN-CS-1 were asked and they formed the first page of the questionnaire. ICCN-CS-1 is a self-assessment tool consisting of 144 items (six sum variables). The scale measures basic competence in intensive and critical care nursing. Theoretically, basic competence is divided into clinical competence and professional competence. Clinical competence consists of three subdomains: principles of nursing care, clinical guidelines, and nursing interventions. Professional competence consists of four subdomains: ethical activity and familiarity with health care laws, decision-making, development work, and collaboration.

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I'm sorry for pulling pranks." "It's 'cuz I liked you so much." "And I wanted to make sure you did, too." "I know you loved me." "I was always grateful." "I didn't say this before but" "I love you." "Se-jin," "I love you." "Stop!" "Stop!" " Sorry to keep you waiting." " It's okay, sir." "It's crazy around here today." "You probably already know why I asked you in here." "We're making some personnel changes." "You'll be sent to Line 3 as of tomorrow." "They're short of workers there." "Is there Seong-nae Station there?" "What?" "What about Han River on the way to Kang-byun Station?" "What are you talking about?" "I'm sorry, sir." "Resignation" "Why are you suddenly taking a year off?" "I'll probably look back on this and regret it." "But it hurts too much now" "I can't do anything." "Something came up." "I'm taking the year off." "Thank you for everything." "It's been months." "Don't you have anything to say?" "Wanna go for drinks?" "What?" "In this broad daylight?" "I don't get people who drink." "It's 'cuz they have weak will." " What's that on your shirt?" " Huh?" "I thought it was a dream." "I remember who was with me then." "What do you like?" "Out of the blue?" "Well, girls like shopping and clothes." "What about you?" "Sugar coated crullers." "And the zoo." "Try to learn to drink." "I like women who can drink well." "How much is enough?" "Maybe..." "a bottle of so-ju?" "A bottle of so-ju!" "A bottle of so-ju!" "What's that?" "Answer the phone, So-hyun!" "I found it!" "2494!" "This is where we first met." "Now, it's time to light up the Tree of Hope." "Ready?" " One!" " One!" " Two!" " Two!" " Three!" " Three!" " Is this Jin-man's phone?" " Ji-eun!" "Stupid, you didn't forget our promise?" "Ji-eun." "You look well." "Wait, Jin-man." "Please don't come to me." "I can't see you now." "I'm married." "I know." "I'm sorry," "I couldn't wait for you." "It's okay." "You kept your promise." "That's enough." "Are you happy?" "Yes." "Now I know why you wanted to meet on a total eclipse." "Why?" "'Cuz it's beautiful." "I'm just glad I can see it with you." "That'll do." "So-hyun!" "Don't go!" "There's something I have to tell you!" "I don't understand why you asked me to teach you how to drink." "Or why my shirt got stained by the iris." "And what it is you desperately want." "And why" "you have to just watch it from afar like a rainbow." "I don't understand." "So, I was thinking." "Will you teach me?" "Then I'll teach you what I didn't realize till now." "Why I've been so blind to someone so special." "I'll tell you everything." "Until you can drink a whole crate full of so-ju." "Se-jin, happy birthday!" "Happy birthday, Se-jin!" "I officially declare Se-jin Jang as Jon-won Lee's boyfriend." "Hi, Se-jin!" "It's me." "I want to start by apologizing." "All those pranks I pulled on you." "It's 'cuz you looked so cute when you panic." "I couldn't resist seeing it over and over." "I wanted to make many fun memories with you." "It feels like a dream when I'm with you." "I never want to wake up." "From my happy dream." "August 20th, 2003." "I saw him sleeping on the train again." "He seems nice." "Idiot!" "I kept staring but he just slept." "September 5th, 2003." "He glimpsed at me exactly 24 times today." "Was it the short skirt I was wearing?" "No." "He looked at my eyes." "Hello." " Hi." " Hi." "Joo-won," "Thank you for allowing me to dream." "Free hugs!" "Free hugs!" "That idea's worth a Nobel Peace Prize." "There's nothing warmer than a hug." "You're right." "Free hug." "Let's wait together." "Let's not get ahead of ourselves." "Or erase the past completely." "We'll just take it slow." "And wait together." "I'd like that." "No one can beat me at waiting." "Ji-woo?" "Can I ask you a favor?" "Sure, go ahead." "Can I touch your Adam's apple?" "So, this is how it feels." "There!" "GAM Woo-sung, CHOI Gang-hee UM Tae-woong" "JUNG Il-woo, LEE Yeon-hee RYU Seung-ryong, LIM Jung-eun" "Directed by LEE Han" "Presented by Big House I Vantage Holdings" "an Ozone Film production" "executive producers CHEONG Eui-seok, KIM Sun-yong, CHIN Hee-moon, JUNG Suk-young screenplay by SIHN Dong-ick" "producer KIM Sang-o" "My memories of her are sometimes so real the present seems more like a dream." "Memories." "They're like the wind." "You never know when or how it'll blow." "Sir?" "You haven't slept at all." "Anything I can help you with?" "Seoul..." "It must've changed a lot, right?" "How long have you been away?" "For 6 years." "I left the other half of my heart there." "And this one's pounding like a drum." "Hello?" "Son!" "It's dad." "Uh-huh." "Are you playing video games again?" "It's not just a game, dad." "I'm busy, gotta go." "That kid..." "A simple idea won't do." "We need a phenomenal event." "Like the World Cups, people going crazy." "Crazy, excited," "A total eclipse." "The moon's shadow covers the sun." "A total eclipse." "The sun and moon uniting as one." "Hey, mister!" "Wait!" "Love, First" "Good morning, sir." "Stop pacing, So-hyun!" "You're making me dizzy!" "Today's the last day for registering, right?" "You asked me that 3 times!" "Want me to say it again?" "Yes, today's the last day to register!" "That's strange." "Are you registering or not?" "Black bean noodles and dumplings!" " Over here, please." " Okay." " Good job everyone." " Bye." "Have a great day, ma'am." "Hey, So-hyun!" " Take out the dirty dishes." " Yes." "My only source of solace." "Excuse me." "Oh, hi!" "You came to register?" "Ah, yes." "But who..." " You're in Korean Lit, too?" " Yes!" "Sorry, I'm running late." "He doesn't remember me." "Oops, my bag." "Hey, wait!" "Yes?" "The sticker," "here." "Thank you." "Bye." "Seoul Metro" "The train is now departing." "Three years earlier Stop sulking, boy!" "I'm way older than you!" "If you don't like the way I talk, go find someone else." "Fine." "When we officially start dating," "I won't call you boy." "We've been seeing each other everyday for over a year." "You ignored me again!" "Man..." "How do we get home now?" "That was the last train." "We can't just take any train, when we have 'our train'." "There's no such thing as 'our train'." "Yes, there is!" "2494!" "That's our train!" "There's a tree scratched on the driver's compartment." "And it sounds louder than the others as it pulls in." "What's with that look?" "Honestly?" "You're bizarre." "Bizarre..." "Hey!" "I like that!" "It means I'm special and unique." "You don't love me, do you?" "No!" "That's not it!" "I do love you!" "Liar." "You don't believe anything I say." "How can I?" "You say you live in a dream world." "Let's try it again." "Close your eyes, slowly." "Then open the eyes of your heart." "Slowly." "Can you feel it getting brighter?" "Yeah." "Now, draw what's in your heart." "Joo-won, Hey!" "Let's go." "It's getting late!" "You still don't see what I see, do you!" "Hey!" "What are you doing!" "Get back up here!" "Hey!" "J

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so far. <TJ-> Bercik: more details please ... kernel version, what you've tried, etc. <Bercik> 3.13.0-19-generic, well.. I managed to mount bcache, make filesystem on it.. but when saving/reading from filesystem I don't see expected speeds. <TJ-> Bercik: Was this a fresh new install with new block devices, or conversion of existing file-system(s) <Bercik> It was a fresh install in VM, just to try out how bcache works. <Bercik> I added 2 disk after I finished installing OS. <TJ-> Bercik: If it's in a VM then performance would be dictated by the VM to some extent <interweb> hello <interweb> How do I can gpg a folder ? <oldchinaphone> ++ <Bercik> TJ-, sure, but I can cleary tell that it's not working properly. HDD gets 40MB/s SSD around 220MB/s <Bercik> even in benchmerks inside VM. <licnep> trying to install 14.04, I already freed some 170GB on my HD. What would the install side by side with windows button do? Should I just click that or partition manually? <kupo_> doesnt it ask you how much you want to use?like 8 gigs or whatever <licnep> forget it i think i'll do it manually just to be sure. What about just a single ext4 / partition and a swap partition? (how much swap do i need for hibernation if i have 4 gigs of ram? <licnep> kupo_: i already reduced the win partition by 170GB so all that space is empty and i will use it all for ubuntu <kupo_> swap.i think 500 Mb or 750 <kupo_> i did too much on mine on accident and did like 3 gigs. but oh well <licnep> if i recall correctly you needed swap to be at least as much as the ram for hibernation to work. But maybe that changed, i'm not sure <kupo_> 500 or under is enough easily <kupo_> you may be right <kupo_> which is why mine is 3.50 <kupo_> i have hibernation issues . and since i use SSD i just shutdown now <licnep> makes sense <licnep> yea i never managed to get hibernation to work on my old laptop <licnep> hopefully it will work on this one, but i know there are still a lot of problems about hibernation on linux <kupo_> yeah. it worked perfectly for me before. but since i reinstalled Os. i have to do it via terminal. then it works fine <TJ-> Bercik: Does "lsblk" show the bcache devices correctly configured? <Bercik> give me a moment plz. I clread configuration and starting over.. <levo> any idea about how to convert a text searchable pdf file to a pdf image file? (formulas in the former aren't readable in e-reader) <ningu> I'm getting some weird locale errors on a new server. I've installed language-pack-en-base, /etc/default/locale is set to en_US.UTF-8, and my env vars are set properly I believe. however I get errors like <ningu> perl: warning: Setting locale failed. <ningu> to make it stranger these errors occur for one user on the server but not another. <ningu> any idea what's going on or how to debug it? <drfoo_> greetings , doing a dist-upgrade ran into a snag <drfoo_> Processing triggers for man-db ... <Bercik> TJ-, sorry I just got a call and have to go. Are u available here most of the time? I'd like to continue with you if possible. <drfoo_> ...usr/lib/man-db/manconv -f UTF-8:ISO-8859-1 -t UTF-8//IGNORE -q: Segmentation fault (core dumped) <drfoo_> process is hung <drfoo_> whats the best way to get out of this? <drfoo_> kill process and reboot <Scotty__> Hello, Yesterday I updated my Compat drivers on kernel 3.8 After that My screen resolution is all messed up. Xrandr shows that the current resolution (incorrect one) is the only resolution this supports. I tried to add my normal resolution on xrandr but got nothing. I tried install fglrx drivers, but that didnt help either. Does anyone have any suggestions? <trism> ningu: try a: sudo locale-gen en_US.UTF-8; <Scotty__> It should be noted, that previous kernel versions without this driver and patch work fine. <ningu> trism: already did that :( <trism> ningu: what is the output you are getting from running: locale; <wieczorek1990> Handwritten music recognition survey. Still need some more replies. Please aid me: https://docs.google.com/forms/d/1wKc1yrfM4pwytpPDU91s5U14KxemtRUFtG7YOtgK7LQ/viewform <ningu> trism: it generates a bunch of locales including en_US.UTF-8 <ningu> trism: sorry, I ran locale-gen with no args <ningu> and the output was for that <blind> Is there a way to do an apt-get install and specify certificate and private key? I know I can put it in apt.conf.d/45rulesname but that's not working so i'd like to try it manually. <kane77> hi, what may be the reason that I cannot kill process? <TJ-> blind: See "man apt-get" and "--option" <kane77> I ran a game via Steam, but it was unresponsive so I used xkill to kill the window, but now I have a process that I'm not able to kill with kill -9 <ningu> trism: when I run "locale" I get: locale: Cannot set LC_CTYPE to default locale: No such file or directory <ningu> what is the default locale? <ningu> oh, wait. I think I see what's going on. <semak> Hello <Scotty__> It should be noted, that previous kernel versions without this driver and patch work fine. It should be noted that previous kernel verisons w/out the driver or patch work fine. Any suggestions? <blind> TJ-: have you done apt-get -o for ssl information before? maybe my syntax is wrong?: '' apt-get update -o "Acquire::https::example.com={Verify-Peer \"true\"; Verify-Host \"true\"; CaInfo \"/etc/apt/ssl/CA.crt\"; SslCert \"/etc/apt/ssl/user.crt\"; SslKey \"/etc/apt/ssl/user.key\";};" '' <TJ-> blind: ouch!!! <limac> hi I'm getting this error after installing bumblebee with nvidia-331 in ubuntu 13.10: ... the class has no package named 'primus-libs-ia32' ... <limac> anyone know what to do? <TJ-> blind: For that I'd use "--config-file" <blind> do you know, though, is that syntax correct? It's not working in a case where the conf file WAS working. <blind> hm using -c did work. so syntax must be incorrect.. <blind> everybody on google is only doing this for proxy info :| <TJ-> blind: enable the Debug::* options <HelloWorld321> I like Empathy, but I don't notice it's notifications if I'm afk. I'm really only worried about my Momma, who's listed as my only "Favorite" contact. But its very normal for me to shut down my computer at the end of the day and see tray messages like "Are you there? Are you there?", and I'd like my Momma to think I'm not ignoring her. :( <HelloWorld321> So the question is: should I change IMs, or is there a way to get Empathy to do more to grab my attention? <cjae> Does ubuntu still use hdparm? <cjae> In /etc/hdparm.conf there is literally no settings that are not uncommented <g1_> My friend typed some "umask 000" command and lost root access. Cannot login to his own account. Recovery mode is also not showing on ubuntu. Any methods to get back root access via guest account or try ubuntu? <majorhat> g1_: hey <majorhat> Hey <blind> TJ-: i got it. i had to do -o Acquire::https::example.com::Verify-Peer="true" -o Acquire::

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soul of fatherly disbelief. _How could my seed contribute to such stupidity?_ Or maybe he would say: "Babes in the Wood?" knowing well that Jeremy knew nothing more. And so, guilty, irritated and with time on his hands, Jeremy stood in due course in the pizza-fragrant atrium of the library, shaking rain off his umbrella before going inside. "Back for that Babes in the Wood file," Jeremy said when he saw that Gil was manning the Social Sciences desk. Gil recognized Jeremy and offered something friendlier than a smirk, although not yet as unguarded as a smile. "You just can't get enough, can you?" the librarian said. "I have a problem." In the carrel he took a deep breath, eyes on the ceiling, before diving in. He read all the articles, top to bottom. When he finished each one he ticked it off on a separate list he had made and turned the sheets face down on the left side of the file folder. He drew a diagram on another piece of paper, a lopsided Stanley Park. He drew in the Reservoir Trail, where the bodies had been found. He marked the dates of death and discovery: 1947, 1953. He registered the fact that the bodies, thought to be a boy and girl for decades, surrendered the DNA of brothers when examined just a few years ago. He considered Miss Harker's story, plotting her course through the park as he imagined the day. He marked the spots where she had seen the woman with the children, entering the forest here, emerging near the bear cages over here, running through the rose gardens. He sketched the alternate routes she might have taken, looping into the forest and returning. He turned next to the handwritten notes. They were journal entries, a careful record, although the handwriting was exceedingly scattered. Letters slanted different directions within a single word, words themselves floating free of the lines or sinking into the line below. The pages looked old, although they were not dated with a year. Maybe the writer had been caught up in the precise limits of the moment being lived, and the future (in this case the future reader) had been an impossible abstraction. Jeremy took a breath, preparing himself, then read. _Some introductory words:_ [the text began] _It should be understood that my interest in this place is longstanding. I have expected for some time that I should return here once my study achieved a certain focus, and that this return might represent the culmination of all previous work_. Jeremy leaned back in his chair, rolled his head back and looked at the ceiling. "God," he said. How had he not seen it coming? These words were, to say the least, somewhat _Professorial_. Jeremy leaned forward again and considered the page more closely. The only thing wrong was the illegible handwriting, cursive but barely. Each letter, each stroke within each letter, was individual, separate from the word. As if the words might disassociate from one another any minute, the letters within each word disband and fly off the page. The Professor had only a few pretensions in the material realm, but penmanship and fine writing accoutrements were definitely two. Jeremy recalled him signing field trip approval slips with a LeGrand Montblanc Bordeaux, and for special occasions unsheathing a huge Pelikan fountain pen made of bottle-green glass with inlaid silver birds. His handwriting matched the equipment: elegant, aloof and singular. Broad, flat strokes (only a particular obscure nib would do) leaning distinctly left on the page, despite the Professor being right-handed. It was so dense and consistent from top to bottom that a complete page of his writing had a distinctive uniform brocade. And then there were the touches. The final _r_ in Papier, for example. It didn't finish in the little dimpled anthill you were taught in penmanship classes, but formed itself like the printed _r_ , a haughtier letter entirely: a short, sharp vertical stroke, with a flaring finish, tapering dramatically up and to the right. The same way, every time. Someone with bad handwriting and a similar interest? Was there anyone with a similar interest? A colleague? Jeremy read on. _What I couldn't have known is that Miss Harker would provide this focus. Witnesses, after all, are not my interest. The murder of the Babes in the Wood, as a murder in itself, was not really my concern. And yet I was interested in this girl, in how she had acted out her heartbreak at leaving Vancouver among these trees on the same day as the murder. And how by doing so she had unwittingly cemented herself into the story, into the landscape from which she had been uprooted, the same landscape of which these children had become a tragic part_. _I went and interviewed her earlier this year. We had tea, spoke at length. She told me the things I knew already: the woman, the two children. But she told me something else, far more interesting. She_ _told me of a premonition, a vision that unfolded under a cloud of fear. She thought she might have fainted; she found herself on her back, the forest rising above her. The air was suddenly dark and in the darkness the forest was filled with people, with sounds_. _When she came to, there had been a young man there. Skinny and ragged. He disappeared into the forest, but he had touched her forehead as she lay. She knew so, she said, from a smudge she found there later_. _Enter Caruzo. I have wondered about his role, and this visit (after many) I am determined to lay this matter finally to rest. I hope he will answer my questions. I hope also that I can last. This work presents a mental and physical test. Tonight, to begin, I will hike across the hillside a safe distance and set up my own camp_. _August 13_ _Drizzling at seven-thirty in the evening_... There followed a week of weather reports, while the author waited for Caruzo to reappear. Then, a little further down: _August 21_ _We aren't talking about much yet, but he has consented to show me around. Caruzo, for the record: tall and heavy, 230 pounds. Age difficult to guess: fifty, sixty even. Large nose. Black and grey, distant eyes; he is caked in evidence of his surroundings. Dirt lines his face and neck and lives under his nails_. _What I know about his past is limited. He speaks of voices. He was institutionalized at one point. Received electroshock. Schizophrenia, I believe_. _He carries nothing, has no evident totem. No toby. Talks in riddles, repeating words like incantations. His are mad, angelic ramblings_. The weather reports and geographic detail resumed as Caruzo slipped out of reach into the forest. Jeremy skimmed down two weeks to find where the story resumed. _September 9_ _Caruzo has returned. Two excellent days of work. He talks lately of our estrangement: from the earth, from "the garden." He said something very odd: "The two are meant to be together. Just as the two were drawn from the same soil, so too must the same soil hold them, and through it must they be reconciled."_ _He speaks of the children, I'm sure. As if the wrong might be righted by his long presence here. And I sense it is a long time. When asked, he did not appear to know that it is 1987_. _Will the '90s bring better things for him? I don't think anyone in the city yet understands what he might be saying, what he might represent: the first of a latter-day generation that will live as he does_. _An aside: Dr. Tully hung up on me this morning. He rejects this data gathering technique. "We do not believe that anecdote is evidence," he said_. _On other fronts, Hélène grieves. I have broken with my normal practice and begun to call. Each time there are many, many tears_. Jeremy pulled his head out of the carrel sharply. When it came, he thought, understanding came suddenly. _1987. Hélène_. Jeremy hunched back over the yellow pages, reading and rereading the sentences with a new hunger. _Mid-September_ _I have been granted sick leave_. _September 24_ _I have begun to feel less like a visitor and more like a resident, an altogether unexpected pleasure. Caruzo has shown me much. He has covered my tent with maple leaves that overlap downwards and spread onto the ground. In the wet they facilitate run-off and minimize flooding_. _I have lately begun to realize how permanent this arrangement could be. Caruzo has shown me a simple snare for squirrels, a lasso of_ _copper electrical wire. He has shown me how to catch starlings on a stick with peanut butter and glue. Ducks may be netted, although the technique is fiendishly difficult. I am changed by this selective and respectful harvest. The bounty of the park, given up to those who care to know it, binds us to it_.

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various public figures they meet. I honestly believe you can learn quite a lot about a person by watching the way he or she interacts with a person with a disability. In that sense I have found that the conversations which take place before our cameras are often more revealing than the supposedly hard hitting interviews we see on major networks. What I particularly like about this latest film is the chance to watch the way political figures, and the many handlers surrounding them, work so hard to manipulate the way they are portrayed in the media. Often the most interesting part of the interview for us is not the actual interview at all. It's the slightly uncomfortable negotiation which takes place beforehand as we ask them if they will speak with us. I liked being able to include those discussions in this new film. In the past we didn't have the freedom, or good sense, to do that. Arthur Bradford: Over the years we have endeavored to produce How's Your News in many different ways, as a film festival entry, a DVD, an HBO documentary, and even an MTV series. This latest version, a completely independent, pay-per-view online stream/download, is truly the best form of distribution yet. For those of you who feel frustrated by commercial news media, I really urge you to support this kind of thing. Not to get on a high horse, but hey, this is It's the future of independent media. It's a very good thing. Boing Boing/XJ: What's it like working with the correspondents? Arthur Bradford: I've known all of them for so long now, they are some of my oldest friendships. And I do mean friendships. I first met Jeremy when he was just a kid, seven or eight years old. He was a crazy little ball of energy and we all wondered what he was going to be like when he grew up. Would people still think he was cute and charming? He's grown up now and, well, you can decide. Sue calls me up at least once a week, usually more. She is relentless when she's got something on her mind. This latest "How's Your News?" project came about in part because of her prodding. She was leaving messages on my phone saying, "Is this How's Your News horse dead or what? Come on!" Bobby is like an uncle to me. He was an usher at my wedding and plays with my children. I honestly don't know of anyone who can so easily mix and mingle with such a wide array of people. You could take him to a Hell's Angles rally in the morning and he'd have everyone hugging him and then attend a formal White House luncheon an hour later and he'd be cozying up the the Secretary of State. He'd know just how to behave immediately. It's a skill few of us have. I hold our reporters to a high standard. I often feel like I'm the coach and they are my team. I have to assess who is feeling good and who will interact in the most interesting way with a given interviewee. I sometimes get frustrated with the reporters if they ask banal questions or act shy. I let them know it when I think they can do better. But I never feed them questions. That doesn't come off well. The questions need to come from them. If they are not having a good time and showing genuine curiosity then it's not enjoyable to watch. I find directing How's Your News to be exhausting and draining and usually after each one is done I swear I'll never do it again. But then Sue and Jeremy starting calling me up and we end up hitting the road. And in the end I'm glad we do it. Download the documentary. (All images courtesy Arthur Bradford)Sidraž Sidraž () is a settlement in the Municipality of Cerklje na Gorenjskem in the Upper Carniola region of Slovenia. Geography Sidraž is a hill settlement in a shady location east of Šenturška Gora on a saddle between Doblič and Tunjščica creeks. The soil is loamy and there is a spring near the village. Name Sidraž was mentioned in historical sources in 1421 as Schydrachs (and as Sidras in 1449, Sydrasch in 1458, and Schidrass in 1475). The name is of unclear origin. A proposed derivation from *suhi draž is very unlikely for phonological reasons, and the village name is more likely based on a truncated personal name. References External links Sidraž at Geopedia Category:Populated places in the Municipality of Cerklje na GorenjskemThis application is related to co-pending U.S. application Ser. No. 09/429,519 for A METHOD AND APPARATUS FOR COMMUNICATION USING PULSE DECODING, filed Oct. 28, 1999 and to co-pending and co-owned U.S. application Ser. No. 09/805,854 for METHOD AND APPARATUS TO RECOVER DATA FROM PULSES, filed Mar. 13, 2001, both of which are owned by the Assignee of the present invention and are herein incorporated by reference for all purposes. This invention relates generally to a communication technique and more specifically to techniques for communication by converting arbitrary analog waveforms to sequences of pulses. In co-pending, commonly owned U.S. application Ser. No. 09/429,519, the communication system illustrated in FIG. 1 shows that groups of pulses are supplied to a decoding (decision) device 14. The decoder disclosed therein recovers data from the pulses; for example, by counting pulses. Additional recovery techniques are disclosed in co-pending, commonly owned U.S. application Ser. No. 09/805,854. It is desirable to increase the robustness of systems which employ the techniques disclosed in the foregoing identified applications. The utility of such systems can be further increased by increasing their information carrying capacity. According to the invention, a method and apparatus for a communication circuit is provided to recover information in a received signal. The communication circuit comprises at least two receiver circuits. The received signal is fed to each receiver circuit. Each receiver circuit is configured in accordance with the invention to produce output comprising a group of one or more pulses in response to detecting some portion of the received signal. The output of each receiver is fed to a decision device, which produces one or more symbols. In one embodiment of the invention, the groups of pulses from each receiver are processed by the decision device to produce a single symbol. In this embodiment of the invention, information transmission is more robust due to the redundancy of the information. In another embodiment of the invention, the groups of pulses from each receiver are processed to produce a symbol from each such group, thereby enhancing information carrying capacity.Sn Ag Solder You May Also Like: Sn-Ag lead free solder is developed as an alternative of lead solders. Generally, commercial tin/silver alloy contains 3% to 5% silver. The Sn/Ag series solders are widely used in soldering electronic assemblies; besides, it is applicable for soldering of jewelry due to its solder point is of high brightness. Unlike the conventional lead solders, they can be utilized in pipe joints which have contact with water and foodstuffs. Sn-Ag lead free solder is featured with high melting point and strong thermal strength. As professional tin silver alloy solder maker, we provide various Sn-Ag solders. The typical product is Sn95Ag5 tin silver solder wires and bars.Q: Content Search and Azure how to move items to the bottom of search results with boosting Similar to my earlier question, I need a way to move certain items to the end of my search results, without using ordering. I have a checkbox field (currently indexed as a string, containing "1" or "0"). I need the checked items ("1") to be at the bottom of the results. Normally, it would be possible to do this with ordering, but since I am boosting certain fields, applying ordering operations screws up the result relevancy. I have a method which adds predicates to my IQueryable object containing: queryable.Where(item => item["discontinued"].Equals("1").Boost(1.0f) || item["discontinued"].Equals("0").Boost(4.0f)); I found from my earlier question that you cannot use negative boost values with Azure search, so I instead tried to give a higher boost for the unchecked items than the checked ones. Is this even possible?: to use two different boost values against the same field depending on the value?. My current testing seems to show that this does not work. A: I found this article which shows a similar approach to boosting (see the end of last code sample, toward the bottom) which confirms that my logic was correct. The error was my choice of boost values. I am boosting around 15 other fields with values in the range of 24 to 50. I guess that in order for this boost rule to have greater influence than the other ones it needs to be orders of magnitude greater (probably) than the other boost values (this must depend on the number of boosted fields and the frequency of occurrences of search terms). What I found was that upping the boost for non-discontinued items to 1000 fixed the problem. Not a very scientific way to fix the problem, but it seems to work. Note that in my case, I need the discontinued boosting to be used like sorting i.e. to take higher precedence than any of the

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. The heavy warm gear is turning in my stomach. My hand is the hand of a stranger. Music is still playing. I must have swayed to the music because Winnie Gunn has seized my forearm with both hands. "Are you all right, Doctor?" she whispers. "Fine." "We are still waiting for your diagnosis, Dr. More," says Buddy with the gentleness of victory. "I found no significant pathology." "Louder!" from the back benches. The Director cups his ear. "I said I found no significant pathology." "No significant pathology," says Buddy as gently as Perry Mason beating Hamilton Burger for the thousandth time. "And what is your recommendation, Doctor?" "Discharge him." "Discharge him," repeats Buddy. "He can't walk or talk, and if he could, he would presumably return to his former atrocious behavior. And yet you want to discharge him. As cured, Doctor?" "If indeed there was nothing wrong with him." "You think there was nothing wrong with him?" "No. That is, yes." "Then what's he doing here in a wheelchair?" Titters. I shrug. "Dr. More, what do you think his chances are of recovering from his stroke?" "You mean, assuming he's had one." "Very well. Assuming he's had one." "Very small." "And if he did recover, what are the chances he'd return to his former mode of behavior?" "Very large." "Do you recall his former behavior?" I am silent. "Allow me to refresh your memory, Doctor." Again Buddy flips through the chart. "These," he explains to the amphitheater, "are progress reports during the last year of the patient's residence at the Golden Years Senior Citizen Settlement in Tampa. I quote: "'The subject has not only refused to participate in the various recreational, educational, creative, and group activities but has on occasion engaged in antisocial and disruptive behavior. He refused shuffleboard tournament, senior softball, Golden Years gymkhana, papa putt-putt, donkey baseball, Guys and Gals à go-go, the redfish rodeo, and granddaddy golf. He refused: free trip to Los Angeles to participate in Art Linkletter III's "the young olds," even though chosen for this trip by his own community. "'Did on two occasions defecate on Flirtation Walk during the Merry Widow's promenade. "'Did on the occasion of the Ohio Day breakfast during the period of well-wishing and when the microphone was passed to him utter gross insults and obscenities to Ohioans, among the mildest of which was the expression, repeated many times: piss on all Ohioans! "'Did in fact urinate on Ohio in the Garden of the Fifty States. "'Was observed by his neighbors on Bide-a-wee Bayou to be digging furiously with a spade on the patio putt-putt, defacing same. When asked what he was digging for, he replied: the fountain of youth.'" More titters from the student roosts. Buddy goes on: "'Despite extensive reconditioning in the Skinner box, the patient continued to exhibit antisocial behavior. This behavior,'" Buddy hastens to add, "'Occurred before his stroke last month.'" "If he had a stroke," I say. "If he had a stroke," Buddy allows gravely. "Well, Doctor?" "Well what?" "What would you do with him?" "Discharge _him_." "To suffer another thirty years?" asks Buddy, smiling. "To cause other people suffering?" "At least he'd have a sporting chance." "A sporting chance to do what?" "To avoid your packing him off to Georgia, where they'd sink electrodes in his head, plant him like a carrot in that hothouse which is nothing more than an anteroom to the funeral parlor. Then throw the Euphoric Switch—" "Doctor!" interrupts the Director sternly. "Aaah!" The students blush at the word _funeral_. Girls try to pull their dresses down over their knees. Buddy flushes angrily. The Director is angrier still. "Doctor!" He levels a quivering finger at me, then crooks it, summoning me. Craning down, he croaks into my ear. "You know very well that the patient is present and that there is no guarantee that he cannot understand you." "Excuse me, sir, but I hope—indeed I have reason to believe—that he does understand me." The Director goes off into a fit of coughing. His eyes bulge glassily. Handkerchiefs fly in and out of plackets in his coat. The students are in an uproar. Cheers from the Knotheads, boos from the Lefts. "This is too much!" The Director throws up both hands. Now he's grabbed me, hooked me with his claws like the ancient mariner. "It's my mistake, Doctor," he croaks. "My putting you on patient-staff status. I beg your pardon. It is only too clear that your illness does not yet permit you to function." "I can function, sir," I tell him, speaking into his great hairy convoluted ear. "You'll see." "Be careful, Doctor!" The powerful old hands squeeze my arm by way of warning. "Proceed!" Mr. Ives's bright monkey eyes have begun to snap again. "I repeat," I say to the back rows. "If Mr. Ives is going to be referred to Happy Isles of Georgia, which is nothing but a euthanasia facility, he has the right to know it and to prepare himself accordingly. And he has the right to know who his executioner is." "I warned you, Doctor!" The Director is on his feet and shouting. "Perhaps you'd better go back to the ward, to A-4." "Yes sir," I say. Perhaps he is right. The students, struck dumb, gaze at me, gaze at each other. "Sir!" It is Buddy, advancing toward me, hands clasped behind his back. He holds one hand up to quiet the uproar. The other hand is still behind him. "Sir!"—to the Director, in a loud voice. "I submit to you, sir, that you are mistaken!" "Eh?" The Director cups his ear. "Sir, you do an injustice both to Dr. More as well as to your own clinical judgment!" "Eh? How's that?" "Your first decision about Dr. More was quite correct. Your confidence in him is not misplaced. His illness does not in the least interfere with his functioning. In short, sir, I submit to you that his odd behavior today cannot be laid to his illness at all. The truth is—" Buddy, quick as a cat, steps behind me, embraces me with one arm, with the other hidden hand claps a mask over my face. His grip is like iron. There is nothing to do but squirm and, at length, gasp for breath. Three, four, five seconds and Buddy flings one arm up like a cowboy bulldogging a steer. He holds the dial aloft for all to see, presents it to the Director like the bull's ears. "Point three percent ethyl alcohol. The truth is Dr. More is drunk as a lord!" Relieved laughter from the students—along with the gasps. At least they recognize a familiar note of buffoonery. Even the Director looks relieved despite himself. "Fun is fun," he announces to no one in particular. "But The Pit may be getting out of hand." Moira has shrunk even farther into the tunnel. Unbuckling my physician's bag, I take out my modified lapsometer. Buddy makes way for me, giving my arm a friendly squeeze, handing me on to the patient with a reassuring smile. _You see,_ his smile tells the students, _it's all in the spirit of The Pit. More and I are not mad at each other._ "Your patient, Doctor." Your witness, Mr. Burger. Twenty years and Ham Burger never won a case. "Thank you, Doctor, but I don't want the patient. I want you." A beehive murmur. Buddy holds up both hands. "It's all right!" he cries, smiling. "Turnabout is fair play. Dr. More is going to diagnose me. Why not? He is going to measure, not my blood alcohol, but my metaphysical status. The device he holds there—correct me if I'm wrong, Doctor—is the More Quantitative-Qualitative Ontological Lapsometer." Laughter from the left. "Qualitative-Quantitative," I correct him. More laughter from the left. Consternation from the right benches. Stony stares from my colleagues. But the Director's glossy eyes bulge amiably—at least he is relieved to see the tone change to the acceptable medical-farcical

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this.volume = target.value; event.preventDefault(); }, _volume: 0, get volume() { return this._volume; }, set volume(volume) { if (!volume) volume = 0; if (this._volume == volume) return; Lunettes.willChange(this, "volume"); this._volume = parseInt(volume, 10); var elements = document.getElementsByClassName(this.Exported.ClassNames.volume); for (var i = 0; i < elements.length; i++) { if (elements[i].value != volume) elements[i].value = volume; } Lunettes.didChange(this, "volume"); }, /** * @param {Event} event */ timelineValueChanged: function(event) { var target = event.currentTarget; if (window.PlatformView.isSeekable()) window.PlatformView.setPosition_(target.value / target.getAttribute('max')); }, _position: 0, get position() { return this._position; }, set position(newPosition) { if (!newPosition) newPosition = 0; if (this._position == newPosition) return; this._position = newPosition; var elements = document.getElementsByClassName(this.Exported.ClassNames.timeline); for (var i = 0; i < elements.length; i++) elements[i].value = newPosition * elements[i].getAttribute('max'); }, PlatformWindowController: function() { return window.PlatformWindowController; }, PlatformWindow: function() { return window.PlatformWindow; }, /** * @param {string} className */ contentHasClassName: function(className) { var content = document.getElementById(this.Exported.Ids.content); return content.hasClassName(className) != -1; }, /** * @param {string} className */ removeClassNameFromContent: function(className) { var content = document.getElementById(this.Exported.Ids.content); content.removeClassName(className); }, /** * @param {string} className */ addClassNameToContent: function(className) { var content = document.getElementById(this.Exported.Ids.content); content.addClassName(className); }, // JS -> Core close: function() { this.PlatformWindow().performClose(); }, miniaturize: function() { this.PlatformWindow().miniaturize(); }, zoom: function() { this.PlatformWindow().zoom(); }, /** * @param {Event} event */ togglePlaying: function(event) { if(this.contentHasClassName(this.Imported.ClassNames.playing)) window.PlatformView.pause(); else window.PlatformView.play(); event.preventDefault(); }, /** * @param {Event} event */ enterFullscreen: function(event) { this.PlatformWindowController().enterFullscreen(); event.preventDefault(); }, /** * @param {Event} event */ leaveFullscreen: function(event) { this.PlatformWindowController().leaveFullscreen(); event.preventDefault(); }, videoResized: function() { if (window.PlatformView.videoDidResize) window.PlatformView.videoDidResize(); }, windowResized: function() { this.videoResized(); }, windowFrame: function() { var platformWindow = this.PlatformWindow(); var origin = { x: platformWindow.frameOriginX(), y: platformWindow.frameOriginY() }; var size = { height: platformWindow.frameSizeHeight(), width: platformWindow.frameSizeWidth() }; return { origin: origin, size: size }; }, /************************************************* * Event handlers */ /** * Key events * @param {Event} event */ keyDown: function(event) { var key = event.keyCode; // Space" key if (key == 0x20) this.togglePlaying(); 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document.addEventListener('mouseup', this._mouseUpListener, false); document.addEventListener('mousemove', this._mouseDragListener, false); }, /** * @param {Event} event */ mouseUpForWindowDrag: function(event) { document.removeEventListener('mouseup', this._mouseUpListener, false); document.removeEventListener('mousemove', this._mouseDragListener, false); this._mouseUpListener = null; this._mouseDragListener = null; }, /** * @param {Event} event */ mouseDraggedForWindowDrag: function(event) { var dx = this.mouseDownPoint.x - event.screenX; var dy = this.mouseDownPoint.y - event.screenY; var mouseDownOrigin = this.windowFrameAtMouseDown.origin; this.PlatformWindow().setFrameOrigin__(mouseDownOrigin.x - dx, mouseDownOrigin.y + dy); }, /************************************************* * Window Resize */ /** * @param {Event} event */ mouseDownForWindowResize: function(event) { // It is reasonnable to only allow click in element that have a resize class if (!event.srcElement.hasClassName(this.Exported.ClassNames.resizePlatformWindow)) return; this.saveMouseDownInfo(event); this.PlatformWindow().willStartLiveResize(); this._mouseUpForWindowResizeListener = this.mouseUpForWindowResize.bind(this); this._mouseDragForWindowResizeListener = this.mouseDraggedForWindowResize.bind(this); document.addEventListener('mouseup', this._mouseUpForWindowResizeListener, false); document.addEventListener('mousemove', this._mouseDragForWindowResizeListener, false); }, /** * @param {Event} event */ mouseUpForWindowResize: function(event) { document.removeEventListener('mouseup', this._mouseUpForWindowResizeListener, false); document.removeEventListener('mousemove', this._mouseDragForWindowResizeListener, false); this.PlatformWindow().didEndLiveResize(); }, /** * @param {Event} event */ mouseDraggedForWindowResize: function(event) { var dx = event.screenX - this.mouseDownPoint.x; var dy = event.screenY

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=ints[1]&1;}staticvoid__initramdisk_size(char*str,int*ints){if(ints[0]>0 &&ints[1]>=0)rd_size=ints[1];}#endifstaticint__initchecksetup(char*line){inti,ints[11] ;#ifdefCON FIG _ B L K _ D E V _ I D E/ * i d e d r i v e r n e e ds t he b a s i cs tri n g , r ath e rtha npre-processedvalues*/if(!s trncmp(line,"ide",3)||(!strncmp(line,"hd",2)&&line[2]!='=')){ide_setup(line);re turn1;}#endiffor(i=0;raw_params[i].str;i++){intn=strlen(raw_params[i].str);if(!strncmp (line,raw_ p a r a m s [ i ] . s t r , n ) ){ ra w _ p a ra m s [ i ].setup_ fu nc(li n e + n, N U L L ) ; return1;}}for(i=0;cooked_p arams[i].str;i++){intn=strlen(cooked_params[i].str);if(!strncmp(line,cooked_par ams[i].str,n)){cooked_params[i].setup_func(get_options(line+n,ints),ints);return1;}}re turn0;}/*t h i s s h o u l d b e a p p r o x 2 B o * o M i p st o st a r t ( not e i ni t i a lsh i f t ) , a n d w i llstillworkevenifinitiall ytoolarge,itwilljusttakeslightlylonger*/unsignedlongloops_per_sec=(1<<12);/*Thi sisthenumberofbitsofprecisionfortheloops_per_second.Eachbittakesonaverage1.5/HZseconds .This(lik e t h e o r i g i n a l ) i s a l i tt l e b e t t er tha n 1%* / #d ef ineLPS_PREC 8 v o i d _ _ i nitcalibrate_delay(void ) { unsignedlongticks,loopbit;intlps_precision=LPS_PREC;loops_per_sec=(1<<12);prin tk("Calibratingdelayloop...");while(loops_per_sec<<=1){/*waitfor"startof"clocktick*/ti cks=jiff i e s ; w h i l e (t i c k s= = j if f i e s) / *not h ing * /;/ *G o . . * /t i c k s = ji f f i e s ; _ _ delay(loops_per_sec);tic ks=jiffies-ticks;if(ticks)break;}/*Doabinaryapproximationtogetloops_per_second settoequaloneclock(uptolps_precisionbits)*/loops_per_sec>>=1;loopbit=loops_per_sec;whi le(lps_ p r e c i s i o n -- && ( l o o p b i t> > = 1 ) ) { loo p s _ p er_ s e c| =loo p bit;ti c k s=j i f f i es;while(ticks==jiffies) ;ticks=jiffies;__delay(loops_per_sec);if(jiffies!=ticks)/*longerthan1tick*/loo ps_per_sec&=~loopbit;}/*finally,adjustloopspersecondintermsofsecondsinsteadofclocks*/l oops_p e r _s e c * = H Z ; / * R o u n d t h e va l u e a n d pr int i t*/ p r in tk ( "%lu. % 02 l uB o goM I P S \ n",(loops_per_sec+2500) /500000,((loops_per_sec+2500)/5000)%100);}/**Thisisasimplekernelcommandlinepar singfunction:itparses*thecommandline,andfillsinthearguments/environmenttoinit*asapprop riate. A n y c m d - l i n e o p t i on i s t a k e n t o b eane n v ironm ent *v a ri a bleifitco n t a i n s t h echaracter'='.**Thisro u tinealsochecksforoptionsmeantforthekernel.*Theseoptionsarenotgiventoinit-theya reforinternalkerneluseonly.*/staticvoid__initparse_options(char*line){char*next;intarg s,env s ; if ( ! * l i n e ) r et u r n; a r g s = 0 ; e n vs= 1;/ * TER Mi ssetto'l i n u x'by d e f a u l t * / n ext=line;while((line=ne xt)!=NULL){if((next=strchr(line,''))!=NULL)*next++=0;/**checkforkerneloptionsf irst..*/if(!strcmp(line,"ro")){root_mountflags|=MS_RDONLY;continue;}if(!strcmp(line,"r w")){ r o o t _ mo u n t f l a g s & = ~ M S _ R D O N L Y ; co nt i n u e ; } if(!s t rc m p(line , "d e b u g ") ) { console_loglevel=10;cont inue;}if(!strncmp(line,"init=",5)){line+=5;execute_command=line;/*IncaseLILOis goingtobootuswithdefaultcommandline,*itprepends"auto"beforethewholecmdlinewhichmakes*t heshe l l t h i n k i t s h o u l d e x ecut e a s c ri ptw it h suc hn am e .*S o weigno r e a l l a r g u m e n t s entered_before_init=... [MJ]*/args=0;continue;}if(checksetup(line))continue;/**Thencheckifit'sanenviro nmentvariableor*anoption.*/if(strchr(line,'=')){if(envs>=MAX_INIT_ENVS)break;envp_init [++en v s ] = l i ne ; } e lse { i f ( a r g s > = M A X _ I NI T _A R G S)brea k ;arg v _ i ni t [ + + a r g s ] = l i ne;}}argv_init[args+1]=N ULL;envp_init[envs+1]=NULL;}externvoidsetup_arch(char**,unsignedlong*,unsigned long*);#ifndef__SMP__/**Uniprocessoridlethread*/intcpu_idle(void*unused){for(;;)idle() ;}#de f i n e s m p _ i n it ( ) d o{ } whi l e ( 0 ) #el s e /* *M ul t i p r oces s or i dle t h r ead i s i n a r ch/...*/externintcpu_idle (void*unused);/*Calledbybootprocessortoactivatetherest.*/staticvoid__initsmp_ init(void){/*Getotherprocessorsintotheirbootupholdingpatterns.*/smp_boot_cpus();smp_th reads _ r e a d y = 1 ; s m p _ c o m m e n c e ( ) ; } # e ndifex te rnvoidin i ti a liz e _ s ec o n d a r y ( v o id);/**Activatethefirstpro cessor.*/asmlinkagevoid__initstart_kernel(void){char*command_line;#ifdef__SM P__staticintboot_cpu=1;/*"current"hasbeensetup,weneedtoloaditnow*/if(!boot_cpu)initial ize_s e co n d a r y ( ) ; bo ot _ c p u =0 ; # e n d if/ * * In te r ru p ts a re s t i l l d i s a b l e d . Do n e c e ssarysetups,then*enablethe m*/printk(linux_banner);setup_arch(&command_line,&memory_start,&memory_end); memory_start=paging_init(memory_start,memory_end);trap_init();init_IRQ();sched_init(); time_ i n i t ( ) ; p ar s e _ o p t i o n s( c o m m an d_ l in e) ; /**H A CKA L E R T ! T h i s i s

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<provider selected="true" editor-type-id="text-editor"> <state relative-caret-position="153"> <caret line="9" column="5" selection-start-line="9" selection-start-column="5" selection-end-line="9" selection-end-column="5" /> </state> </provider> </entry> </component> </project>Article content continued The company may need to set aside funds for a US$16.7 million note maturing in November, apart from as much as US$110 million maturing next April, according Raymond James analyst Andrew Bradford, although lenders are expected to provide debt relief. “Lenders would be far better off to amend covenants and work with operators through the downturn if for no other reason than equipment liquidated through a receiver could effectively go ‘no-bid’ in today’s market,” Bradford said in a note. Much-needed cash may be generated with the sale of its Russian and Kazakhstan pressure pumping business, which analysts said could fetch between $50 million and $200 million. The company would not divulge details on the unsolicited offer, nor a timeline of when a possible deal could be concluded. “We believe the most likely buyer is Rosneft and Trican is likely to realize cash proceeds of $175 million-$200 million in the context of the current market,” CIBC’s Morrison said, based on the assumption that 85 per cent of the $242 million generated from Trican’s international business is estimated to be from the region. Industry indicators suggest more pain is on the way for oilfield services companies. “The full impact of throttled back E&P spending was felt in April, with wells drilled and completions down 62 per cent and 74 per cent year-on-year, respectively,” said Dan MacDonald, analyst at RBC Dominion Securities Inc. Well completions were down 74 per cent in April year-on-year, fracturing-intensive gas well completion activity was down 51 per cent versus last year, and oil well completions were down 80 percent. Trican peer Ensign Energy Services Inc. recently described the upcoming summer in Canada as “very tough” and said it expects to use only a fourth of its equipment. Meanwhile, Precision Drilling Corp. has negotiated relief for the two principal covenants of its revolving credit facility. “We are entering a cyclical downturn that will parallel 2009 and in some cases, will be worse than 2009,” Morrison said. “First quarter was the start and Q2 will be much worse while Q3 and Q4 will be depend on commodity prices getting better.”Responding to Simkulet's objections to the two tragedies argument. The two tragedies argument (2TA) has been raised as a response to the argument against abortion from spontaneous abortion (or miscarriages). According to this argument against the antiabortion position (AAP), miscarriages should be of great concern for proponents of this position since they result in a greater amount of deaths of human beings than induced abortions do. According to critics of AAP, this fact undermines its plausibility, since proponents of the AAP either must try to prevent miscarriages to the same extent as they try to prevent abortions or abandon their opposition to at least some abortions-which are not acceptable options for proponents of APP. The claim of 2TA is that one can differentiate between induced abortion and miscarriages due to the fact that the former involves the act of killing of another human being. This fact adds a tragedy to the tragedy that both abortions and miscarriages result in - the death of a human being - and contributes to justifying the choice of proponents of AAP to prioritise the prevention of abortions rather than miscarriages. In this response, I defend 2TA against criticism that claims that this argument is: (1) inconsistent with the AAP and (2) trivialises the death of the fetus. My claim is that the first line of criticism rests on a misunderstanding of the premises of 2TA while the second line of criticism rests on a disanalogous thought experiment. I therefore conclude that these objections fail.Q: Airflow ExternalTaskSensor execution timeout I'm using airflow.operators.sensors.ExternalTaskSensor to make one Dag wait for another. dag = DAG( 'dag2', default_args={ 'owner': 'Me', 'depends_on_past': False, 'start_date': start_datetime, 'email': ['[email protected]'], 'email_on_failure': True, 'email_on_retry': False, 'retries': 2, 'retry_delay': timedelta(minutes=10), }, template_searchpath="%s/me/resources/" % DAGS_FOLDER, schedule_interval="{} {} * * *".format(minute, hour), max_active_runs=1 ) wait_for_dag1 = ExternalTaskSensor( task_id='wait_for_dag1', external_dag_id='dag1', external_task_id='dag1_task1', dag=dag ) If something seriously wrong happens with upstream Dag and it fails to complete during the given time period, I want upstream Dag (ExternalTaskSensor operator) crash as well, instead of hanging forever. How can I add a timeout to ExternalTaskSensor? I'm looking into documentation, but it does not seem to have a timeout parameter or something similar. What should I do? https://airflow.readthedocs.io/en/stable/_modules/airflow/sensors/external_task_sensor.html A: The ExternalTaskSensor does take a timeout argument in seconds. It inherits the argument from BaseSensorOperator (https://airflow.apache.org/_modules/airflow/sensors/base_sensor_operator.html). If you pass it timeout=60 on instantiation, it will fail after 60 seconds. /*--------------------------------*- C++ -*----------------------------------*\ | ========= | | | \\ / F ield | OpenFOAM: The Open Source CFD Toolbox | | \\ / O peration | Version: 2.3.0 | | \\ / A nd | Web: www.OpenFOAM.org | | \\/ M anipulation | | \*---------------------------------------------------------------------------*/ FoamFile { version 2.0; format ascii; class volScalarField; location "0"; object Ydefault; } // * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * // dimensions [0 0 0 0 0 0 0]; internalField uniform 0.0; boundaryField { fuel { type fixedValue; value uniform 0.0; } air { type fixedValue; value uniform 0.0; } outlet { type inletOutlet; inletValue uniform 0.0; value uniform 0.0; } frontAndBack { type empty; } } // ************************************************************************* // ``defined`` =========== ``defined`` checks if a variable is defined in the current context. This is very useful if you use the ``strict_variables`` option: .. code-block:: twig {# defined works with variable names #} {% if foo is defined %} ... {% endif %} {# and attributes on variables names #} {% if foo.bar is defined %} ... {% endif %} {% if foo['bar'] is defined %} ... {% endif %} When using the ``defined`` test on an expression that uses variables in some method calls, be sure that they are all defined first: .. code-block:: twig {% if var is defined and foo.method(var) is defined %} ... {% endif %} Q: Android : How to stop all threads start in fragment when change fragment I have an activity with many fragments inside. In one fragment, I run some periodically thread that use some command such as getActivity().runOnUiThread(), so when switch to different fragmemnt, those statement will make NullPointException. I know how to stop a thread, but don't know which method to put this code inside. (it means: when switch fragment, which method that fragment will always run before switch). Please help me about this problem. Thanks :) A: Thanks to help of Leco. The best way is put those code into onPause. You can see more detail in this link: Fragment Lifecycle Help this post will useful for anyone meets same problem with me. Q: Are the total false positives and false negatives of

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\int_{\mathbb{R}}\nabla \rho_{{\varepsilon},r,r_0} \cdot (2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta.$$ Then there exists a constant $C = C(d,J)$ such that $${\left\|U\right\|}_{L^1(\Pi_T^{r_0})} \le C\frac{{{\Delta x}}^2}{r^3}\left(1 + \frac{{{\Delta x}}}{r}\right){\left\|A(u_{{\Delta x}})\right\|}_{L^1([0,T];BV({\mathbb{R}}^d))}.$$ The $BV$ norm may be replaced by the $L^1$ norm at the expense of an extra factor $r^{-1}$. Clearly, $$\begin{gathered} {\left\|\int_{\mathbb{R}}\nabla \rho_{{\varepsilon},r,r_0} \cdot (2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta\right\|}_{L^1(\Pi_T^{r_0})} \\ \le {\left\|\nabla \rho_{{\varepsilon},r,r_0}\right\|}_{L^\infty(\Pi_T^{r_0} \times {\mathbb{R}};{\mathbb{R}}^d_\infty)}{\left\|(2\nabla -({D_+}+ {D_-})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\|}_{L^1(\Pi_T^{r_0} \times {\mathbb{R}};{\mathbb{R}}^d_1)}. \end{gathered}$$ By Young’s inequality for convolutions, $$\begin{aligned} {\left\|\partial_{x_i}\rho_{{\varepsilon},r,r_0}\right\|}_{L^\infty(\Pi_T^{r_0} \times {\mathbb{R}})} &\le {\left\|\chi(A(u);\cdot)\right\|}_{L^\infty(\Pi_T \times {\mathbb{R}})}{\left\|J_{\varepsilon}\otimes \partial_{x_i}J_r \otimes J_{r_0}\right\|}_{L^1({\mathbb{R}}\times {\mathbb{R}}^d \times {\mathbb{R}})} \notag \\ &\le {\left\|\partial_{x_i}J_r\right\|}_{L^1({\mathbb{R}}^d)} \le 2{\left\|J'\right\|}_\infty r^{-1}. \end{aligned}$$ We have $$(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (2\partial_{x_i} -({D_+}^i + {D_-}^i))J_r \otimes J_{r_0}.$$ Using Taylor expansions with remainders, $$\begin{aligned} \left(({D_+}^i + {D_-}^i)-2\partial_{x_i}\right)J_r(x) &= \frac{1}{2{{\Delta x}}} \int_0^{{{\Delta x}}}(z-{{\Delta x}})^2 \partial_{x_i}^3J_r(x_i+z)\,dz \,\prod_{j \neq i}J_r(x_j) \\ &\qquad + \frac{1}{2{{\Delta x}}} \int_{-{{\Delta x}}}^0(z+{{\Delta x}})^2 \partial_{x_i}^3J_r(x_i+z)\,dz \,\prod_{j \neq i}J_r(x_j) \\ &=: \partial_{x_i}(\varphi^i_1(x) + \varphi^i_2(x)), \end{aligned}$$ see for instance [@KRS2014 p. 25]. Hence $$(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \partial_{x_i}\left(\chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (\varphi^i_1 + \varphi^i_2) \otimes J_{r_0}\right).$$ By Young’s inequality for convolutions $$\begin{gathered} {\left\|(2\partial_{x_i} -({D_+}^i + {D_-}^i))\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\|}_{L^1(\Pi_T^{r_0} \times {\mathbb{R}})} \le {\left\|\chi(A(u_{{\Delta x}});\cdot)\right\|}_{L^1([0,T] \times {\mathbb{R}};BV({\mathbb{R}}^d))}\\ \times {\left\|\varphi^i_1 + \varphi^i_2\right\|}_{L^1({\mathbb{R}}^d)}. \end{gathered}$$ Note that ${\left\|\chi(A(u_{{\Delta x}});\cdot)\right\|}_{L^1([0,T] \times {\mathbb{R}};BV({\mathbb{R}}^d))} = {\left\|A(u_{{\Delta x}})\right\|}_{L^1([0,T];BV({\mathbb{R}}^d))}$. Now, as $\partial_{x_i}J_r(x_i + z) \le r^{-3} {\left\|J''\right\|}_\infty{\mathds{1}_{{\left|x_i+ z\right|} \le r}}$, it follows that $$\begin{aligned} {\left\|\varphi^i_1\right\|}_{L^1({\mathbb{R}}^d)} &= \frac{1}{2{{\Delta x}}}\int_{\mathbb{R}}\Bigl|\int_0^{{{\Delta x}}}(z-{{\Delta x}})^2 \partial_{x_i}^2J_r(x_i+z)\,dz\Bigr|\, dx_i \\ &\le \frac{(r + {{\Delta x}})}{{{\Delta x}}r^3}{\left\|J''\right\|}_\infty\int_0^{{{\Delta x}}}(z-{{\Delta x}})^2\,dz \\ &\le \frac{1}{3}{\left\|J''\right\|}_\infty \frac{{{\Delta x}}^2}{r^2}\left(1 + \frac{{{\Delta x}}}{r}\right). \end{aligned}$$ The same estimate applies to $\varphi_2^i$. \[est:5\] Let ${\mathscr{T}}$ be the term from Lemma \[lemma:ContractionLemma\], that is, $${\mathscr{T}}= \int_R ({\mathrm{sign}_\varepsilon\left(\zeta-A(u)\right)} \star J_{r_0} \otimes J_r)(\Delta - {D_-}\cdot {D_+})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\,d\zeta.$$ Then there exists a constant $C = C(d,J)$ such that $${\left\|{\mathscr{T}}\right\|}_{L^1(\Pi_T^{r_0})} \le C\frac{{{\Delta x}}^2}{r^3}\left(1 + \frac{{{\Delta x}}}{r}\right){\left\|A(u_{{\Delta x}})\right\|}_{L^1([0,T];BV({\mathbb{R}}^d))}.$$ At the cost of an extra factor $r^{-1}$, the $BV$ norm may be replaced by the $L^1$ norm. First note that ${\left|{\mathrm{sign}_\varepsilon\left(\zeta-A(u)\right)} \star J_{r_0} \otimes J_r\right|} \le 1$, so $${\left|{\mathscr{T}}\right|} \le {\left\|(\Delta - {D_-}\cdot {D_+})\rho_{{\varepsilon},r,r_0}^{{\Delta x}}\right\|}_{L^1(\Pi_T \times {\mathbb{R}})}.$$ Now, $$(\partial_{x_i}^2 - {D_-}^i{D_+}^i)\rho_{{\varepsilon},r,r_0}^{{\Delta x}}= \chi(A(u_{{\Delta x}});\cdot) \star J_{\varepsilon}\otimes (\partial_{x_i}^2 - {D_-}^i{D_+}^i)J_r \otimes J_{r_0}.$$ Using a Taylor expansion [@KRS2014 p.24], $$\begin{aligned} (\partial_{x_i}^2-{D_-}^i{D_+}^i)J_r(x) &= \frac{1}{6{{\Delta x}}^2}\int_0^{{\Delta x}}(z-{{\Delta x}})^3\partial_{x_i}^4J_r(x_i + z)\,

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in order to perform the task by legislation. Moreover, the act sets forth in sufficient exactness the things to be considered by the Department in reaching its determinations. It sets forth just who shall be liable under the act and how the Department shall determine their liability. The act provides for an administrative hearing at the instance of any person affected or aggrieved by the administration of the act, and allows judicial review under the Administrative Review Act of any final decision of the Department. (See Sheldon v. Hoyne, 261 Ill. 222.) The discretion allowed the Department is therefore far from arbitrary, being subject to all these limitations, rules, and provisions of law. *422 After a careful examination of sections 19 to 25 of article IX, inclusive, of the Mental Health Code, we are of the opinion that none of these sections are vulnerable to the constitutional objections advanced and that the superior court of Cook County erred in holding those sections of the statute unconstitutional and in enjoining their enforcement. The decree of the superior court of Cook County is therefore reversed and the cause is remanded, with directions to vacate the decree heretofore entered and to dismiss plaintiffs' suit for want of equity. Reversed and remanded, with directions. Mr. JUSTICE SCHAEFER took no part in the consideration or decision of this case. Effect of nonspecific interactions of the hepatitis B surface antigen with the solid phase on its detection by two-site immunoradiometric assay. Two-site immunoradiometric assay (Austria II-125, procedure B, Abbott) was used to detect hepatitis B surface antigen (HBsAg) in chronic carrier sera from clinically healthy subjects or from kidney transplant or hemodialysis patients. The titration curves of some high-titered sera showed a prozone-like effect; this corresponded in two such sera LB and MA, to congruent to 80% inhibition of HBsAg detection in undiluted serum relative to a 1:800 dilution. The nature of the inhibition in the above two sera was investigated. We found that the inhibition depended on the time of first incubation but not on the affinity of capture antibodies. Nonspecific adsorption of HBsAg to the solid phase during the first incubation with inhibitory sera and elution of the thus adsorbed antigen during the second incubation, with the resulting neutralization of 125I-labeled anti-HBs, appeared to cause the inhibition of detection observed. The inhibition was prevented by addition of the detergent Triton X-100 to serum or by elution of adsorbed antigen prior to the second incubation, thus indicating that further improvements of the HBsAg immunoradiometric assay may be possible. 239 A.2d 215 (1968) The STATE of Delaware v. Willle Lee JACKSON. Superior Court of Delaware, New Castle. February 16, 1968. *216 Francis A. Reardon, Deputy Atty. Gen., for the State. Henry A. Wise, Jr., Wilmington, for defendant. OPINION CHRISTIE, Judge. The defendant was arrested for the possession and sale of marijuana following the search of his premises pursuant to a search warrant. Thereafter, the defendant was indicted for the sale and possession of "a narcotic drug, to-wit: Marijuana" in violation of 16 Del.C. § 4702(a). Subsequently, the defendant moved to suppress the evidence obtained by the search warrant on the ground that the warrant authorized a search for narcotic drugs and the return showed marijuana had been seized, which defendant contends is not a narcotic drug. The defendant also moved to dismiss the indictment on two grounds: 1) the statute under which the indictment was brought is unconstitutional in that it includes in the body a subject not set forth in the title of the act in violation of Article 2, Section 16 of the Delaware Constitution, Del. C.Ann. and, 2) the indictment failed to advise the defendant of the offense charged because the statute on which it is based prohibits the sale and possession of many substances the legislature did not intend to prohibit. The statute under which the defendant was indicted is 16 Del.C. § 4702(a). This Section was originally enacted as a part of the Delaware Narcotic Drug Act adopted on April 18, 1935 as 40 Del.Laws Ch. 225. The title of the Narcotic Act read in pertinent part: "An Act Defining and Relating to Narcotic Drugs and the use thereof Regulating and Prohibiting the Manufacture, Possession, Control, Sale; * * *." The body of the act when enacted and as reenacted in the Code in 1953 defines marijuana as a narcotic drug. The defendant contends the above quoted title is unconstitutional because it violates Article 2, Section 16 of the Delaware Constitution which provides that: "No bill or joint resolution except bills appropriating money for public purposes, shall embrace more than one subject, which shall be expressed in its title." Defendant's contention is that marijuana is not a narcotic drug, and therefore, is not a subject which can be included within the statute, the title of which indicates that narcotics is the subject dealt with. The first question is whether the defendant may properly challenge the constitutionality of a title to an act the provisions of which were subsequently reenacted as part of the Delaware Code. Such a challenge has been entertained but only in cases where the significance of the reenactment as part of the Delaware Code was not raised or decided. Randolph v. Wilmington Housing Authority, 37 Del.Ch. 202, 139 A. 2d 476 (1958), State of Delaware v. Chase, 11 Terry 383, 131 A.2d 178 (1957). The title of the act by which the Delaware Code was adopted in 1953 has been held to be sufficient to meet the constitutional requirements of Article 2, Section 16 of the State Constitution. Monacelli v. Grimes, 9 Terry 122, 99 A.2d 255 (1953). The title of the act adopting the Delaware Code necessarily covers the statutes, acts and laws included therein at the date of its adoption. Since the title of the Delaware Code is adequate for the entire Code and meets constitutional requirements an attack on the validity of a title of an act which was reenacted as part of the Delaware Code is futile. State v. Durham, Del.Super., 191 A.2d 646 (1963). If the defendant were permitted to attack the title of an act which was enacted prior to the Delaware Code and later reenacted as a part thereof, an issue then might arise as to whether the title was *217 adequate. This in turn might depend on whether or not marijuana is a narcotic drug within the accepted meaning of the term. Questions similar to this have been raised in other jurisdictions which, like Delaware, have included provisions as to marijuana in their narcotic laws. Wherever the issue has been raised it has been held in effect that marijuana is a narcotic drug for purposes of statutory interpretation. Spence v. Sacks, 173 Ohio St. 419, 183 N. E.2d 363 (1962); People v. Stark, 157 Colo. 59, 400 P.2d 923 (1965); Commonwealth v. Leis and Weiss, Mass.Superior Court No. 28841-1 (1967); Gonzales v. State, 163 Tex.Cr.R. 432, 293 S.W.2d 786 (1956); People v. Rumley, 100 Cal.App.2d 6, 222 P.2d 913 (1950); Escobio v. State, Fla., 64 So.2d 766 (1953). Under Delaware decisional law, the constitutional provision in question does not require the title of a new statute to go into details or to furnish an abstract, synopsis, or index of the contents of the act. Monacelli v. Grimes, supra. The constitutional requirement is satisfied if the title is sufficiently informative so as to put on notice parties interested in the general matter in such a manner as would lead them to inquire into it. In Re Opinion of the Justices, 4 Storey 366, 177 A.2d 205 (1962). The portion of the title of the narcotics law, quoted above, was sufficiently informative so as to lead interested persons to inquire into the full details of the act. I am of the opinion that the Delaware Narcotics Law satisfies the requirements of Article 2, Section 16 of the State Constitution even before it was reenacted as part of the Delaware Code. There is still a third reason why the defendant cannot prevail in his attack on the title of the original act. The title includes notice that the term "narcotic drugs" is defined therein. With such notice in the title the legislature is especially free to define the term differently than might be the usual definition of such term. In this act the legislature went on to provide that "`narcotic drugs' means * * * marihuana, marijuana, and all allied drugs of the same botanical family * * *." Defendant's motion to dismiss the indictment based on the contention that the title of the underlying act is constitutionally deficient is denied. The next question is whether the indictment advised the defendant of the offense with which he is charged. Under Criminal Rule 7(c), Del.C. Ann., an indictment must contain a plain, concise written statement of the essential facts constituting the offense charged. The indictment must apprise the defendant with such detail as to enable him to prepare his defense and to plead the proceeding as a bar to a second prosecution for the same offense. Demonia v. State, Del., 210 A.2d 303 (1965). The defendant argues that the term "marijuana" is so broad that it covers many substances which the legislature did not intend to cover and, therefore, the indictment alleging the sale and possession of marijuana is so indefinite that it fails to

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3986, 387, 634, 3369, 10539, 1561, 253, 7616, 1897 ]

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the district court’s denial of his motion for a new trial pursuant to Rule 33 of the Federal Rules of Criminal Procedure. We are not persuaded. We review a district court’s disposition of a motion for new trial for abuse of discretion. See United States v. Martinez, 763 F.2d 1297, 1312 (11th Cir. 1985). “On a motion for a new trial based on the weight of the evidence, the court need not view the evidence in the light most favorable to the verdict. It may weigh the evidence and consider the credibility of the witnesses.” Id. Motions for a new trial 11 Case: 15-11695 Date Filed: 04/12/2016 Page: 12 of 13 are granted sparingly and only for an exceptional case. See id. A new trial for example, may be the appropriate remedy when the government’s witnesses have been severely impeached and the government’s case has been marked by discrepancies. See id. This is not an exceptional case, and the weight of the evidence presented did not warrant granting Mr. Brooks a new trial. The government’s witnesses were not impeached. The government’s case was circumstantial, but it was not marred by discrepancies. Mr. Brooks’ competing theory that his son or someone else repeatedly downloaded the child pornography and refined the files over time was heard and rejected by the jury. Mr. Brooks’ alternative theory did not present any discrepancies in the government’s case; it simply presented a different view of the facts and attempted to shift the blame to someone else. Although it did provide a counter weight to the evidence put forward by the government, it did provide enough weight to warrant a reversal of the district court’s denial of a motion for new trial. In sum, the district court did not abuse its discretion in denying Mr. Brooks a new trial. The evidence presented at trial did not preponderate heavily against the guilty verdicts, such that to let them stand would be a miscarriage of justice. See Martinez, 763 F.2d at 1313. 12 Case: 15-11695 Date Filed: 04/12/2016 Page: 13 of 13 VI We affirm Mr. Brooks’ convictions. AFFIRMED 13 Photos by Jun Cayas “You have so much here. You just have to come together.” - Charlie Co Who would have thought what three days with multiple artists coming from the different parts of the country could bring? It all…Q: Moq test passes even when verifying both Times.Once() and Times.Never() on same method call I'm using Xunit to test the Create method on my CarController and I'm using Moq to mock my CarRepository. I'm then using mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Once()); to check that the Create method on my repository is being called. However the test passes irrespective of whether I call it or not. Here is a complete example where I verify both that Create is called once AND that it is called never. My test passes when I would have expected it to fail. using System; using Moq; using Xunit; namespace Test { public class CarTest { [Fact()] public async void CreateTest() { var mockCarRepository = new Mock<CarRepository>(); var carController = new CarController(mockCarRepository.Object); carController.Create(new Car { Make = "Aston Martin", Model = "DB5" }); mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Once()); mockCarRepository.Verify(m => m.Create(It.IsAny<Car>()), Times.Never()); } } public class CarController { private readonly CarRepository _repo; public CarController(CarRepository repo) { _repo = repo; } public void Create(Car car) { _repo.Create(car); } } public class Car { public virtual String Make { get; set; } public virtual String Model { get; set; } } public class CarRepository { public virtual void Create(Car car) { // DO SOMETHING } } } When I debug the test, although it still passes, I notice that the following exception is thrown: A first chance exception of type 'Moq.MockException' occurred in Moq.dll Additional information: Expected invocation on the mock should never have been performed, but was 1 times: m => m.Create(It.IsAny<Car>()) No setups configured. Performed invocations: CarRepository.Create(Test.Car) The exception is expected as I am calling Create once and verifying Times.Never() but I would like my test to fail. What do I need to do to achieve this? Update It turns out that the problem was that I'd marked my test as async - removing that causes it to pass. However the actual code I'm writing will call an async method, so my question is now, how can I verify methods are called when using asynchronous methods? A: See the answer here for an explanation of why async void test methods do not work in xUnit. The solution is to give your test method an async Task signature. async void functionality has been added ready for version 2.0 of xunit, see here for details. The series: We look at manufacturing companies that are using technology to create “smart factories” fit for long-term global competitiveness. Open this photo in gallery Parmalat Canada has retooled its factories to bottle milk in new, recyclable,1.5-litre bottles made of polyethylene terephthalate (PET). They keep milk fresher for a longer period of time. Handout/Lactancia Regular, unadorned milk remains a staple, and that’s part of a problem. “Don’t mess with my milk, don’t change it,” said Marco De Palma, lamenting the typical consumer perception in Canada. Story continues below advertisement Canadians tend to see milk as fresh, unchanged, sacrosanct, but then they look for other beverages when they get bored with it. So, as general manager of fluid milk and distributor sales at Parmalat’s office in Toronto, Mr. De Palma wants to – in fact needs to – make milk more exciting, as does the rest of the industry. Innovation means bringing in new manufacturing methods, new milk flavours, new formulas into a sector that’s aging and somewhat stuck in the past. Made all the more difficult by a product that spoils so quickly. But innovation is happening, because it has to, industry watchers say. Overall milk consumption continues to decline. Almond and soy drinks continue to siphon off customers. The usual link between milk consumption and demographics – that is, when the population rises, overall milk consumption typically rises – has weakened, some note. Many new Canadians may more readily reach for a glass of yogurt-based lassi or a salty, yogurty ayran. And among those consumers buying milk regularly, alternatives such as lactose-free milk are stealing away customers, in this age of growing dietary intolerance. “There is a mix of what people are buying, but overall consumption is still in decline,” Mr. De Palma said. To stem this drop, Parmalat Canada, a subsidiary of Parmalat SpA of Italy, has launched a new plastic bottle for its Lactania PurFiltre brand. This may hardly seem revolutionary, but for Parmalat, it’s a step within a larger strategy. The bottles' size (1.5 litres) is out of the norm, different than regular one- or two-litre cartons, or bags and common milk jugs. They’re made of polyethylene terephthalate (PET) rather than the usual high density polyethylene (HDPE) for plastic jugs, with a bottle shape designed to make it look unlike other milk bottles on the dairy shelf. This, of course, entailed equipping plants with new machinery and production methods, including equipment that can handle other kinds of milk processing, which can give the milk a longer shelf life. Parmalat hopes that the new-look, PET bottles, which are recyclable and BPA free, are a step in keeping milk fresher, longer, broadening its reach into new markets. Story continues below advertisement “Those bottles will have 60 days of shelf life after production, compared to a carton which hovers between 39 to 50 days, depending on the product. That shelf life gives us two things: one, the ability to launch innovation and sell it from coast to coast as much as we can; and two, to introduce new categories of milk in provinces that currently don’t have them,”

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Biography Channel, NBC and more. He also wrote and directed two sold-out 2014 BroadwayWorld charity concert events featuring all-star casts, EVERYTHING'S COMING UP BROADWAYWORLD.COM: A JULE STYNE TRIBUTE and THE LORD & THE MASTER: BROADWAYWORLD.COM SINGS THE MUSIC OF ANDREW LLOYD WEBBER & STEPHEN SONDHEIM.namespace CruiseControl.Common { using System.Runtime.Serialization; /// <summary> /// The arguments for a query. /// </summary> [DataContract] public class QueryArguments { #region Constructors /// <summary> /// Initializes a new instance of the <see cref="QueryArguments"/> class. /// </summary> public QueryArguments() { this.DataToInclude = DataDefinitions.Both; } #endregion #region Public properties #region FilterPattern /// <summary> /// Gets or sets a REGEX pattern for filtering the actions. /// </summary> /// <value> /// The filter pattern. /// </value> [DataMember] public string FilterPattern { get; set; } #endregion #region DataToInclude /// <summary> /// Gets or sets the data to include. /// </summary> /// <value> /// The data to include. /// </value> [DataMember] public DataDefinitions DataToInclude { get; set; } #endregion #endregion } }Q: How can I pass data from another class to a GUI? How do I pass data/values from one class to another using GUI? I'm trying to pass the message2 array to namesOut label in GUI. I'm stuck and getting an error. Here's my code: GUI package testClassesGUI; import java.awt.BorderLayout; public class UI extends JFrame { private JPanel contentPane; /** * Launch the application. */ public static void main(String[] args) { EventQueue.invokeLater(new Runnable() { public void run() { try { UI frame = new UI(); frame.setVisible(true); } catch (Exception e) { e.printStackTrace(); } } }); } /** * Create the frame. */ public UI() { setDefaultCloseOperation(JFrame.EXIT_ON_CLOSE); setBounds(100, 100, 450, 300); contentPane = new JPanel(); contentPane.setBorder(new EmptyBorder(5, 5, 5, 5)); setContentPane(contentPane); contentPane.setLayout(null); JLabel lblDisplayOutNames = new JLabel("Display out names:"); lblDisplayOutNames.setBounds(32, 25, 121, 16); contentPane.add(lblDisplayOutNames); JLabel namesOut = new JLabel(""); //here i need to bring the data namesOut.setBounds(32, 63, 228, 87); contentPane.add(namesOut); } } Logic: Here I'm getting an error. package testClassesGUI; public class Logic { private String[] someArray = { "Great", "World" }; // getter method public String[] message2(){ return someArray; } // setter method public void setSomeArray(String[] someArray){ this.someArray = someArray; } UI logicObject = new UI(); logicObject.namesOut.setText(message2); //here my error misplaced construct(s), variable declaratoridexpected } Your help is much appreciated. A: Put this in your UI constructor. You should create a Logic object in it public UI() { setDefaultCloseOperation(JFrame.EXIT_ON_CLOSE); setBounds(100, 100, 450, 300); contentPane = new JPanel(); contentPane.setBorder(new EmptyBorder(5, 5, 5, 5)); setContentPane(contentPane); contentPane.setLayout(null); JLabel lblDisplayOutNames = new JLabel("Display out names:"); lblDisplayOutNames.setBounds(32, 25, 121, 16); contentPane.add(lblDisplayOutNames); JLabel namesOut = new JLabel(""); //here i need to bring the data namesOut.setBounds(32, 63, 228, 87); contentPane.add(namesOut); Logic logic = new Logic(); <<--- String[] array = logic.message2(); | | String s = ""; | for (String str : array){ | s += str + " "; | } | | namesOut.setText(s); <<---- } You can delete this from your Logic class UI logicObject = new UI(); logicObject.namesOut.setText(message2); International NGOs are instruments of cultural imperialism RIO DE JANEIRO, Brazil – In developing or underdeveloped countries (in Latin America, Africa, Asia and parts of Eastern Europe), the participation of NGOs in the provision of basic public services is increasing. They aim to replace weak and/or poor states in various resource-poor sectors. Some of these NGOs are also involved in state oversight, supposedly in favor of “human rights.” It is easy to point out fundamental problems in these NGOs. States are accountable to their citizens. If their governments fail to live up to the expectations of the masses, they risk being traded or, in more drastic cases, even toppled by an angry population. Who do NGOs respond to? Just to your donors, usually wealthy citizens, foreign governments or powerful corporations. These NGOs pass on to their donors information (true or otherwise) on the beneficiaries to the donors, who then guarantee the donations. But understand: if NGOs succeed in solving the problems they care about, they simply will not be needed anymore. However, it is clear that NGOs will not disappear, and that they do not exist to solve definitively the problems of their interest. The phenomenon of NGOs has exploded since the 1980s, being born in the rich countries of the first world, for very clear reasons. In the global capitalist elite there are distinct degrees of intelligence and sensitivity, and among them a more perceptive layer noted that the implementation of neoliberalism was polarizing societies and generating strong social commotion. Neoliberal politicians, entrepreneurs, and bankers then began to finance and promote a “bottom-up” parallel strategy, with organizations driven by an “anti-statist” ideology whose aim was to appease the masses and at the same time , to promote the dismantling of the state and to demobilize serious political and social organizations. In the 1990s, these NGOs were already thousands and moving around $ 4 billion worldwide every year. One of its main sources of funding has been the World Bank. The point of convergence between interests is clear: NGOs criticize the state from a progressive left-wing perspective, in defense of a supposed civil society, while the right wing does it in defense of the market. In other words, as neo-liberal regimes devastated their own countries and foreign countries, flooding them with cheap imports, crushing them with usurious debts, abolishing labor laws and creating a growing mass of precarious workers, NGOs assumed the role of “self-help” to local communities, deviating from any kind of radical political and social militancy. NGOs, in this sense, are nothing more than a “communal” face of neoliberalism. They are financed by the same characters that cause the problems they are aiming to fight. In this sense, they play a fundamentally depoliticizing and relieving role. Its aim is not to solve problems, but to try to stifle conflicts and make capitalist exploitation more palatable. In this way, the very classification they lead is even fallacious. Considering that they receive funding from capitalist governments, and that they usually work with agencies and departments of these governments, it is not true that these institutions are effectively non-governmental. More recently, NGOs have taken an even more prominent role in the imperialist strategies of the globalist elite. “Human rights” NGOs infest countries considered enemies by the Atlantean governments. There, these NGOs work to undermine the institutional solidity of the enemy countries’ system, instilling “civil society” against their rulers in the name of “human rights,” but for the benefit of the Atlantean governments and international corporations. So it was with the Arab Spring or with the Maidan. NGOs affiliated with George Soros and other financiers and / or funded by the US Department of State have implemented the manuals of

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one on one. Romney and Obama have one more debate, on Monday at Lynn University in Boca Raton, Fla. Although the focus of the final forum is foreign policy, it will be a time for the candidates to make their closing arguments to try to woo undecided voters and motivate their respective bases, whose enthusiasm becomes crucial in a close contest. But after what happened at Hofstra, it’s clear that the real competition will be the fight to the finish, a battle for the battleground states where the election will be decided. The most important are Virginia, Florida and Ohio — with Ohio being perhaps first among equals. After that come Iowa, Colorado and New Hampshire, Nevada, North Carolina and Wisconsin. Few events have changed the race as quickly or dramatically as the first debate. Romney’s clear victory over Obama in Denver turned around the campaign narrative, which was heading toward a premature conclusion that the contest was virtually over. It also shifted polls, both nationally and in the battleground states. How many minds will be changed by what happened on Tuesday night? There is likely to be a boost in enthusiasm among Obama loyalists, and that’s not insignificant. Given that some parts of his coalition, young voters in particular, are not as motivated as they were four years ago, that jolt of energy could be important. Obama advisers know that turning out their voters will be harder for them than it will be for Romney’s team. But Romney’s initial performance did much to generate enthusiasm among his supporters. That’s not likely to be diminished by Tuesday’s debate. After Denver, Republicans began to think it was possible to win. Their enthusiasm going forward is unlikely to slacken. The turnout battle from now until Election Day will be as fiercely fought as was the battle at Hofstra. One of the keys to the outcome will be women, and a big question from Tuesday’s debate is how women will react to what they saw. Romney appeared to be making progress in reducing Obama’s big margins among female voters in the past two weeks. But he may have hurt himself. Just as Vice President Biden’s smiles and laughs during his debate with GOP vice presidential nominee Paul Ryan (Wis.) last week turned off some voters, Romney’s efforts to push back against CNN’s Candy Crowley, who served as moderator, could alienate some women. Heading into the second debate, there was little disagreement that a race that had seemed to be slipping away from Romney in September was back to what strategists in both parties had predicted would be a competitive contest to the end. In the hours before the exchange, the Romney and Obama campaigns offered genuinely conflicting and perhaps self-serving assessments of how things stood — in the battlegrounds and among key demographic groups. Take the state of play in Ohio. Before Denver, Obama had a clear and, in some polls, big lead. In a pre-debate appearance Tuesday in the spin room, Sen. Rob Portman (R-Ohio) told reporters that the race there was even. “Our own tracking indicates it’s a dead heat,” he said. Portman, who has played the president in Romney’s debate preparations, said that before Denver, the challenger was behind by “a big gap,” but added that Romney has made steady progress since then. “Frankly, it wasn’t just a bump after the debate.” Jim Messina, Obama’s campaign manager, offered a counterview. He said the first debate may have tightened the race, but added that the contest always was destined to close in the final month. He also said that Obama was still strong in the Midwest — Ohio, Iowa and Wisconsin. “We continue to have more pathways to 270 votes than Romney,” he said. “All of our pathways are still there. We are where we need to be.” What voters saw Tuesday night was just how big the choice will be in November. Romney and Obama painted dire pictures of what will happen if the other is elected in three weeks. Voters may have heard this before, but it was more sharply etched, with the candidates standing only a few feet apart, than in the television commercials or campaign appearances. Now the campaign turns to fundamentals — one more debate and then a sprint to Nov. 6. The race has been long and hard-fought, but Obama and Romney showed Tuesday night that they have plenty left for the final stretch, and their teams are ready for what comes next.s v prime? True Let w(t) = 6 - t**2 - 3 + 0 - 6*t. Let o be w(-6). Suppose o*b - b - 70 = 0. Is b prime? False Suppose -5999 + 2486 = -3*n. Is n prime? True Suppose -3*z + 13 = -8. Suppose -8 = -3*s + z. Suppose 2*n + s*v - 305 = 0, -3*n - 2*v + 151 = -2*n. Is n a composite number? True Suppose 0 = 33*i - 28*i - 2045. Is i composite? False Is 807/9 + 4/(-6) prime? True Let u(p) = p - 10. Let q be u(8). Is q/8 + (-269)/(-4) composite? False Is ((-2)/(-6))/((-23)/(-66171)) a composite number? True Let y be (-15)/(-6)*8/10. Suppose 335 = -g + y*g. Suppose -d + 6*d - g = 0. Is d a prime number? True Suppose -3*z = -5*y - 64, -12 = -2*z + z - 3*y. Let u = z - -1. Is u prime? True Suppose -4*r + 20 = 4. Is r prime? False Let c = 8 + -4. Suppose c = -4*q - 0*q. Is 0 + 6*4 + q prime? True Suppose 5*z - 33 + 13 = 0, z - 3 = d. Is 2*d/(-5)*-145 composite? True Let d(x) = 3*x**3 - 2*x**3 + 0*x - 5*x + 0*x + 4*x**2 + 2. Let z be d(3). Let y = -28 + z. Is y a composite number? True Let f = -219 + 364. Is f prime? False Let j(d) = -d**3 + 7*d**2 + 10*d - 1. Let r be j(8). Is 522/r + 1/5 a composite number? True Suppose -d = -a - 4*a + 23, -d - 5*a = -27. Suppose -530 = -d*i - 0*i. Suppose 0 = -4*h + i - 81. Is h composite? True Let r(f) = f**2 - 6*f. Let g be r(6). Let h(t) = t + 4. Let y be h(g). Is 1/y - 210/(-24) prime? False Is (-1 - 0)/((-2)/(-53384)*-4) composite? False Let c(v) = 9*v**2 - 5*v + 1. Is c(-5) composite? False Suppose -7*n + 2*n + 10 = 0. Suppose -n*o + 6 = -0*o. Suppose 0*a + 609 = o*a. Is a prime? False Let z(b) = 14*b**2 + b + 1. Is z(-2) composite? True Let o = 6 - 2. Is 9177/49 + o/(-14) a prime number? False Let v = 244 - 165. Is v composite? False Let q = -9 + 14. Suppose 4 = i - m, 5*i - 16 = m - 0. Suppose -267 = -3*r + i*n, -r + q*n = -3*r + 150. Is r composite? True Suppose 0 = -4*t - 5*g - 11 + 34, -3 = -3*t + g. Suppose 0 + t = s. Is ((-33)/s)/((-3)/4) composite? True Suppose 2*o - m = 9, -3*o + 7*o - 3*m = 19. Suppose -o*r - 68 + 304 = 0. Is r a prime number? True Let j be (3 - -15) + (-4)/2. Let w = j + -11. Suppose 147 + 8 = w*z. Is z prime? True Let a = 717 + -304. Is a composite? True Suppose 0 = -12*g + 16*g - 2140. Is g prime? False Let j be 3/(-5) - (-39)/15. Suppose -p - j*i = p - 114, 6 = -3*i. Is p composite? False Let q = -4 - -4. Suppose -4*k + k + 45 = q. Is k composite? True Suppose 4*h + l - 395 = 3*h, 0 = -4*h + 4*l + 1548. Is h a prime number? False Let y(d) = -d

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beijn-K\u00f6\u00df" }, { "CK", "de Kuuk-Enselle" }, { "CL", "Schiile" }, { "CM", "Kammeruhn" }, { "CN", "Schiina" }, { "CO", "Kolumbije" }, { "CP", "de Klipperton-Ensel" }, { "CR", "Kostarika" }, { "CU", "Kuba" }, { "CV", "de kapv\u00e4rdesche Enselle" }, { "CW", "Cura\u00e7ao" }, { "CX", "de Weihnaachs-Ensel" }, { "CY", "Z\u00fcppere" }, { "CZ", "de Tsch\u00e4schei" }, { "DE", "Do\u00fctschland" }, { "DG", "de Diego-Garcia-Ensel" }, { "DJ", "Dschibutti" }, { "DK", "D\u00e4nemark" }, { "DM", "Dominnika" }, { "DO", "de Dommenekaanesche Reppublik" }, { "DZ", "Alljeerije" }, { "EA", "Ze\u2019uta un Meliija" }, { "EC", "\u00c4kwador" }, { "EE", "\u00c4\u00dfland" }, { "EG", "\u00c4j\u00fcpte" }, { "EH", "W\u00e4\u00df-Sahara" }, { "ER", "\u00c4ritreja" }, { "ES", "Schpaanije" }, { "ET", "\u00c4ttijoopije" }, { "EU", "de Europ\u00e4jesche Unijon" }, { "FI", "Finnland" }, { "FJ", "de Fidschi-Endelle" }, { "FK", "de Falkland-Enselle" }, { "FM", "Mikroneesije" }, { "FO", "de F\u00e4rr\u00f6r-Enselle" }, { "FR", "Frankrisch" }, { "GA", "Jabuhn" }, { "GB", "Jruu\u00dfbrettannije" }, { "GD", "Jrenaada" }, { "GE", "Jeorrjije" }, { "GF", "Franz\u00fc\u00fcsesch Jujaana" }, { "GG", "J\u00f6\u00f6nsei" }, { "GH", "Jaana" }, { "GI", "Jibralltaa" }, { "GL", "Jr\u00f6hnland" }, { "GM", "Jambija" }, { "GN", "Jinneha" }, { "GP", "Juadelupp" }, { "GQ", "\u00c4quatorial Jineeja" }, { "GR", "Jriescheland" }, { "GS", "S\u00f6d-Jeorjie un de s\u00f6dlijje Botteramms-Enselle" }, { "GT", "Juwatemaala" }, { "GU", "Juham" }, { "GW", "Jinneha_Bi\u00dfau" }, { "GY", "Jujaana" }, { "HK", "Hongkong" }, { "HM", "de Heart Ensel un de McDonald-Enselle" }, { "HN", "Honduras" }, { "HR", "Krowazije" }, { "HT", "Ha\u2019itti" }, { "HU", "Unjann" }, { "IC", "de Kannaresche Enselle" }, { "ID", "Indoneesije" }, { "IE", "Irrland" }, { "IL", "I\u00dfra\u00e4l" }, { "IM", "de Ensel M\u00e4n" }, { "IN", "Indije" }, { "IO", "Brettesche Besezunge em indesche Oozejahn" }, { "IQ", "Irak" }, { "IR", "Persije" }, { "IS", "I\u00dfland" }, { "IT", "Itaalije" }, { "JE", "J\u00f6\u00f6seh" }, { "JM", "Jammaika" }, { "JO", "Jordaanije" }, { "JP", "Japan" }, { "KE", "Keenija" }, { "KG", "Kirrjiisije" }, { "KH", "Kambodscha" }, { "KI", "Kiribati" }, { "KM", "de Kommoore" }, { "KN", "Zint Kitts un Nevis" }, { "KP", "Nood-Koreja" }, { "KR", "S\u00f6d-Koreja" }, { "KW", "Kuweit" }, { "KY", "de Kaiman-Enselle" }, { "KZ", "Kassakstahn" }, { "LA", "La\u2019os" }, { "LB", "Lebbannon" }, { "LC", "de Ensel Zint-Lutscha" }, { "LI", "Lischteschtein" }, { "LK", "Sri Lanka" }, { "LR", "Libeerija" }, { "LS", "Lesooto" }, { "LT", "Littaue" }, { "LU", "Luxembursch" }, { "LV", "L\u00e4tland" }, { "LY", "Libbije" }, { "MA", "Marokko" }, { "MC", "Monakko" }, { "MD", "Moldaavije" }, { "ME", "et Monteneejro" }, { "MF", "de Zint-M\u00e4\u00e4tes-Ensel" }, { "MG", "Maddajaska" }, { "MH", "de Machschall-Enselle" }, { "MK", "Mazedoonije" }, { "ML", "Maali" }, { "MM", "Birma" }, { "MN", "Mongjolei" }, { "MO", "Makau" }, { "MP", "de n\u00f6\u00f6dlijje Marijanne-Enselle" }, { "MQ", "Machtinik" }, { "MR", "Mautitaanije" }, { "MS", "Mong\u00dferrat" }, { "MT", "Malta" }, { "MU", "Maurizijus" }, { "MV", "Mallediive" }, { "MW", "Malawi" }, { "MX", "M\u00e4xiko" }, { "MY", "Malaisije" }, { "MZ", "Mosambik" }, { "NA", "Namiibije" }, { "NC", "Neuschottland" }, { "NE", "Nijer" }, { "NF", "de Noofok-Ensel" }, { "NG", "Nikaraagua" }, { "NI", "Nikaraaguwa" }, { "NL", "de Nederl\u00e4ng" }, { "NO", "Norrweeje" }, { "NP", "Nepall" }, { "NR", "Nauru" }, { "NU", "Niue" }, { "NZ", "Neuseeland" }, { "OM", "Oman" }, { "PA", "Pannama" },

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Isolated trans-acting loci that affect the expression of one or a few genes appear to be uncommon. Locations of eQTLs in the genome. (A) Map of local and distant eQTLs. The genomic locations of eQTL peaks (x-axis) are plotted against the genomic locations of the genes whose expression they influence (y-axis). The strong diagonal band corresponds to local eQTLs. The many vertical bands correspond to eQTL hotspots. Point size is scaled as a function of eQTL effect size, measured in fraction of phenotypic variance explained. (B) The number of gene expression traits linking to each of 102 identified eQTL hotspots (Methods) are shown as vertical bars. Text labels identify genes in hotspots referred to in the text. The 102 hotspots affected a median of 425 genes, ranging from 26 (a newly discovered hotspot at position 166,390 bp on chromosome III) to 4594 at the previously reported MKT1 hotspot (Zhu et al., 2008) (82% of 5629 genes with any signal at a hotspot; Figure 3B). Three additional hotspots each affected more than half of all genes. They include a previously described hotspot at the HAP1 gene (Brem et al., 2002) (3640 genes affected), as well as two newly detected hotspots on chromosome XIV. A hotspot at 372,376 bp affected 4172 genes and is likely caused by a variant that recently arose in the KRE33 gene in the RM parent used in our cross (Jerison et al., 2017). A hotspot at position 267,161 bp affected 3169 genes and spans the genes GCR2, YNL198C, WHI3 and SLZ1. These results indicate that hotspots can have extraordinarily wide-reaching effects on the transcriptome, with some influencing the expression of the majority of all genes. Widespread effects caused by single loci likely arise from a cascade of effects in which strong primary effects spread through the cellular regulatory network. For example, the BY allele of the transcriptional activator HAP1 carries a transposon insertion that reduces HAP1 function. As expected, the BY allele strongly reduced the expression of known transcriptional targets of HAP1: 26 out of the 69 HAP1 targets present in our data were among the 50 genes with the largest reduction in expression in segregants carrying the BY allele of HAP1 (p<2.2e-16, odds ratio = 138). In total, only 75 direct transcriptional HAP1 targets are known. Unless previous work missed thousands of HAP1 targets, the vast majority of the 3640 trans eQTLs at HAP1 must reflect indirect, secondary consequences of the direct transcriptional effects. HAP1 is an activator of genes involved in cellular respiration. Thus, the many secondary effects of the BY HAP1 allele on gene expression may be mediated by cellular responses to altered metabolism arising from reduced respiration. Our Supplementary Files and Datasets provide detailed information about each hotspot. Source data 8 contains a table that gives an overview of the hotspots, including their location, genes affected (details in Source data 9), and analyses of function (details in Source data 10) and transcriptional regulation (details in Source data 11) of the target genes of each hotspot. Supplementary file 5 visually represents each hotspot region, and Supplementary file 6 displays gene networks formed by the strongest target genes of each hotspot. Causal genes underlying hotspots Functional analysis of eQTL hotspots requires identification of the underlying causal genes, which has been challenging to do systematically. We developed a multivariate fine-mapping algorithm that narrows hotspot positions by leveraging information across the genes that map to each hotspot (Materials and methods). Briefly, we used all genes with an eQTL on a given chromosome and regressed out genetic factors on all other chromosomes and additional non-genetic factors. We reduced the dimensionality of the residual expression levels by singular value decomposition to capture linear combinations of traits that account for most of the variance in residual expression. We scanned the given chromosome for genetic influences on the multivariate distribution of these linear combinations, while controlling FDR via permutations. Finally, we used bootstraps to compute confidence intervals for hotspot locations (Figure 4 and 5). Genes located in hotspot regions. (A) Histogram showing the number of genes located in the hotspot regions. (B) A hotspot on chromosome VIII maps to the gene STB5. From top to bottom: the general region on the chromosome, the empirical frequency distribution of hotspot peak locations from 1000 bootstrap samples (Materials and methods), locations of BY/RM sequence variants (red: variants with ‘high’ impact such as premature stop codons (McLaren et al., 2016); orange: ‘moderate’ impact such as nonsynonymous variants; grey: ‘low’ impact such as synonymous or intergenic variants), and gene locations. The light blue area shows the 95% confidence interval of the hotspot location as determined from the bootstraps. The red line shows the position of the most frequent bootstrap marker. (C) Genes for which the BY allele at the STB5 hotspot is linked to lower expression are enriched for STB5 transcription factor (TF) binding sites in their promoter regions. The figure shows enrichment results for all annotated TFs (grey dots), with the strength of enrichment (odds ratio) on the x-axis vs. significance of the enrichment on the y-axis. The STB5 result is highlighted in red. With this approach, we resolved the locations of 26 hotspots to regions containing three or fewer genes (a total of 58 genes; Figure 4A). Three hotspots contained exactly one gene (GIS1, STB5, and MOT3). We previously identified and experimentally confirmed the causal genes at several major hotspots (MKT1 (Zhu et al., 2008), HAP1 (Brem et al., 2002), IRA2 (Smith and Kruglyak, 2008), GPA1 (Yvert et al., 2003), and the mating-type locus [Brem et al., 2002]). These were all correctly localized by the algorithm, validating this fine-mapping strategy. The 58 genes at 26 high-resolution hotspots are highly enriched for the causal genes underlying the hotspots, making it possible to systematically study the functions of hotspot regulators. These genes were less likely to be essential or to have a human homolog than other yeast genes but did not differ from other genes in their expression level or the number of physical or genetic interaction partners (Supplementary file 7). The hotspot genes had highly significant enrichments for gene ontology (GO) terms related to transcriptional regulation (e.g. GO:0006357 ‘regulation of transcription from RNA polymerase II promoter’: 19 genes among the 58; 4 expected; p=4e-9; Figure 4—figure supplement 1; Source data 12), as well as weaker enrichments for terms related to response to nutrient levels (GO:0031669; ‘cellular response to nutrient levels’: 8 genes, 1 expected, p=6e-6) These analyses indicate that causal hotspot genes are disproportionately involved in transcriptional regulation, a signal that was not picked up in an earlier study with fewer, less-well-resolved hotspots (Yvert et al., 2003). For example, we fine-mapped a new hotspot that affected 382 genes to a single gene, the transcription factor STB5 (Figure 4B). STB5 is a transcriptional activator of multidrug resistance genes (Kasten and Stillman, 1997). A previous analysis suggested reduced activity of the STB5 BY allele compared to the RM allele (Lee and Bussemaker, 2010). Consistent with this observation, we found that the promoters of genes whose expression was lower in the presence of the STB5 BY allele were strongly enriched for STB5 binding sites (Figure 4C). To further examine the role of sequence variation in transcription factor genes, we focused on transcription factors with variants predicted to be damaging to protein function such as premature stop codons or frameshifts. There are eight such genes in our data. Remarkably, six of these (GAT1, HMS1, PUT3, RFX1, SRD1, TBS1) were located in a hotspot, often very close to the estimated peak location (Figure 4—figure supplement 2). None of these expression hotspots have been reported previously, although variation at GAT1 has been reported to influence traits relevant for wine production (Salinas et al., 2012), and a premature stop codon in the RM allele of RFX1 has been linked to reduced activity of this transcriptional repressor (Lee and Bussemaker, 2010). The remaining two transcription factors with predicted damaging mutations did not overlap a hotspot. Of these, a predicted frameshift in YRM1 is very close to the end of the coding region, while a predicted frameshift in STB4 appears to be an annotation artifact: it resides in a region that is annotated as coding but that does not in fact appear to be transcribed (Figure 4—figure supplement 3, [Albert et al., 2014a]). Hotspot genes can also influence mRNA levels more indirectly – for instance, by shaping the cellular response to external stimuli such as nutrient availability. For example, we fine-mapped a hotspot, which influenced 645 genes, to an interval on chromosome VIII containing six genes (Figure 4—figure supplement 4A). One of these is ERC1, which encodes a transmembrane transporter. BY but not RM carries a frameshift in this gene, which removes the last two out of 12 predicted transmembrane helices of the protein (Fehrmann et al., 2013). This variant is known to reduce cell-to-cell variability (or

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Ebersberg, Germany) with the following sequence: *MAP-LC3b*: 5′- CGT CCT GGA CAA GAC CA-3′ (forward), 5′-CCA TTC ACC AGG AGG AA-3′ (reverse); *SQSTM1/p62:* 5′-AGG GAA CAC AGC AAG CT-3′ (forward), 5′-GCC AAA GTG TCC ATG TTT CA-3′ (reverse); *GAPDH*: 5′-CCA GAA CAT CAT CCC TGC AT-3′ (forward), 5′-CAG TGA GCT TCC CGT TCA-3′ (reverse). The evaluated efficiency of each set of primers was close to 100% for both target and reference genes. Real-time PCR was performed using the CFX 96 Real-Time System (Bio-Rad, Hercules, CA, USA) in a 10 µl total volume, using the iTaq SYBR Green Supermix (Bio-Rad), and with 500 n[m]{.smallcaps} primers. PCR cycling conditions were as follows: 94°C for 10 min, 40 cycles at 94°C for 15 s and 60°C for 1 min. Melting curve analysis was performed at the end of each PCR assay as a control for specificity. Data were expressed as *C*~t~ values and used for the relative quantification of targets with the ΔΔ*C*~t~ calculation. To exclude potential bias due to averaging data transformed through the equation $2^{- \Delta\Delta C_{t}}$ to give *N*-fold changes in gene expression, all statistics were performed with Δ*C*~t~ values. Each experiment was carried out with four independent samples. Western blot (WB) analysis and FRA {#s4d} ---------------------------------- NSC34 cells were plated in 12-well multiwell plates at 80 000 cell/ml, transfected as previously described. For dose-dependent analysis, the cells were treated with 10 n[m]{.smallcaps}/100 n[m]{.smallcaps}/1 µ[m]{.smallcaps} Bicalutamide or 10 m[m]{.smallcaps}/100 m[m]{.smallcaps}/1 M trehalose. In the other experiments, the cells were treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. In experiments involving autophagy blockage, 10 m[m]{.smallcaps} 3-MA was added to the cells for the last 48 h. In experiments where proteasome was inhibited, the cells were treated with 10 µ[m]{.smallcaps} MG132 for the last 16 h (overnight treatment). After 48 h, cells were harvested and centrifuged 5 min at 100 *g* at 4°C; the cell pellets were re-suspended in PBS (added of the protease inhibitors cocktail, Sigma-Aldrich) and homogenized using slight sonication as previously described ([@DDU419C63]). Total proteins were determined with the bicinchoninic acid method (BCA assay, Euroclone). PC12/AR.Q112 cells were plated in six-well multiwell plates at 80 000 cell/ml, induced with 1 μg/ml of doxycycline and treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. After 48 h, cells were harvested and centrifuged 5 min at 100 *g* at 4°C; the cell pellets were re-suspended in RIPA buffer (added of the protease inhibitors cocktail, Sigma-Aldrich) and homogenized using slight sonication. The samples were centrifuged 15 min at 15 000 *g* at 4°C. The soluble fraction (supernatant) was separated from the insoluble one and the protein concentration was determined by the BCA assay. The pellet fraction was re-suspended in 20 μl of 4x sample buffer, and a relative amount was loaded into the gel, according to the protein assay on the soluble fraction. WB was performed on 15% SDS--polyacrylamide gel electrophoresis loading 10--15 µg of total proteins. Samples were then electrotransferred to PVDF (polyscreen transfer membrane, PerkinElmer, Waltham, MA, USA) using a semi-dry transfer apparatus (Trans-Blot^®^ Turbo™ Transfer System, Bio-Rad). The membranes were treated with a blocking solution containing 5% nonfat dried milk powder (EuroClone, MI, Italy) in Tris buffered saline with Tween for 1 h and then incubated with the following primary antibodies: (a) rabbit polyclonal AR-H280 (dilution 1 : 3000) to detect wt AR and ARpolyQ; (b) rabbit polyclonal anti-LC3 (dilution 1:4000) to detect LC3; (c) rabbit polyclonal anti-SQSTM1/p62 (dilution 1:4000) to detect SQSTM1/p62; (d) mouse monoclonal anti-α-tubulin (Sigma-Aldrich, dilution 1:4000) to detect total α-tubulin. Immunoreactivity was detected using the following secondary peroxidase-conjugated antibodies: goat anti-rabbit (Santa Cruz, dilution 1:20 000) was used to identify the anti-AR, the anti-LC3 and the anti-SQSTM1/p62 antibodies; goat anti-mouse (sc-2005, Santa Cruz, dilution 1:20 000) was used to identify the anti-α-tubulin antibody. The immunoreactive regions were then visualized using the enhanced chemiluminescence detection kit reagents (ECL prime Western Blotting Substrate, GE Healthcare, Maidstone, UK). The same membranes were subsequently processed with different antibodies to detect the levels of different proteins in the same sample loaded on the gel, after stripping for 10 min at room temperature (StripABlot, EuroClone). FRA was performed by sample filtration through a 0.2 µm cellulose acetate membrane (Whatman, GE Healthcare) using a Bio-Dot SF Microfiltration Apparatus (Bio-Rad) and loading 9 µg (NSC34 cells) of the total proteins or 1.5 µg (PC12) of the supernatant fraction. Slot-blots were probed as described for WB to detect AR.Q46 or AR.Q112. A ChemiDoc XRS System (Bio-Rad) was used for the image acquisition of WB and FRA. Optical intensity of samples assayed with WB or FRA was detected and analyzed using the Image Lab software (Bio-Rad). Fluorescence, IF and microscopy on NSC34 cells {#s4e} ---------------------------------------------- NSC34 cells were plated in 12-well multiwell plates containing coverslips at 70 000 cells/well density, transiently transfected with the plasmid coding for GFP-ARQ48 as previously described and treated with 100 m[m]{.smallcaps} trehalose and/or 100 n[m]{.smallcaps} Bicalutamide and/or 10 n[m]{.smallcaps} testosterone for 48 h. The cells were then fixed and processed as previously described (Sau, 2007). To analyze LC3 and SQSTM1/p62 protein expressions, we used the following primary antibodies: rabbit polyclonal anti-LC3-B antibody 1 : 1000 (Sigma-Aldrich) in 5% nonfat milk, rabbit polyclonal anti-SQSTM1/p62 antibody 1 : 1000 (Abcam, Cambridge, UK) in 5% nonfat milk. Secondary antibodies used were: Alexa 488 anti-rabbit and Alexa 594 anti-rabbit (Life Technologies) 1 : 1000 in milk. Cells were stained with DAPI to visualize the nuclei. An Axiovert 200 microscope (Zeiss Instr., Oberkochen, Germany) equipped with FITC/TRITC/DAPI and combined with a Photometric Cool-Snap CCD camera (Ropper Scientific, Trenton, NJ, USA) was used. Images were processed using the Metamorph software (Universal Imaging, Downingtown, PA, USA). Statistical analysis {#s4f} -------------------- Statistical analysis has been performed using one-tailed Student\'s *t*-test for two group comparisons and one- or two-way ANOVA for three or more group comparisons using the PRISM software (GraphPad Software, La Jolla, CA, USA). *Conflict of Interest statement*. None declared. FUNDING {#s5} ======= This work was supported by Telethon---Italy (GGP07063 and GGP14039) to A.P.; AriSLA Foundation Italy (ALS_HSPB8) to A.P.; Italian Ministry of Labour, Health and Social Affairs (Convenzione Fondazione Mondino/UNIMI) to A.P. and (Giovani Ricercatori) to V.C.; Regione Lombardia to A.P.; Universita' degli Studi di Milano to A.P. and P.R.; Fondazione CARIPLO (2008-2307) to A.P.; Fondation Thierry Latran, France (FTL n. AAP091102) to A.P., Association Française contre les Myopathies (project n. 16406) to A.P. Funding to pay the Open Access publication charges for this article was provided by Fondazione Telethon, Italy. [^1]: E.G. and P.R. equally contributed to this study. WO 2013/139685 A1 relates to a valve for an inhalation device comprising a base in the form of a ring defining a central opening, as well as an upper surface and a lower

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line shown above. Pay attention to the first ID hex code part '''"18d1"'''. That id is used in the following steps to identify this device. Create a new file (as root) <code> sudo gedit /etc/udev/rules.d/51-android.rules </code> with the following content <code> SUBSYSTEM=="usb", SYSFS{idVendor}=="18d1", MODE="0666" </code> Make sure that the text after {idVendor} is the same as the device id found when using the lsusb command. Save and exit the editor.Currently, Department of Homeland Security (DHS) policies permit customs and border authorities to seize and search American citizens’ smartphones and other digital devices when they travel internationally to and from the United States, without a warrant or suspicion of wrongdoing. The FSO subcommittee will hear testimony regarding the history of this so-called “border search exception” to the warrant requirement of the Fourth Amendment and will evaluate the far-reaching privacy implications of DHS’ policy of allowing customs and border officials to seize and search the digital devices of international travelers without a warrant. In April 2017, Dr. Paul joined U.S. Senator Ron Wyden (D-OR) in introducing the Protecting Data at the Border Act (S. 823) to stop this violation of Americans’ Fourth Amendment rights and prevent government officials from requiring Americans to disclose sensitive information on their digital lives in order to leave or re-enter the country. “I think that most Americans could agree that it’s reasonable to let customs officials search suitcases for contraband. What’s unreasonable is that the government lawyers want you to believe that there’s no difference between a suitcase and a smartphone. I disagree, and here again, I think most Americans would, too,” Dr. Paul said in his opening statement. Currently, Department of Homeland Security (DHS) policies permit customs and border authorities to seize and search American citizens’ smartphones and other digital devices when they travel internationally to and from the United States, without a warrant or suspicion of wrongdoing. The FSO subcommittee heard testimony regarding the history of this so-called “border search exception” to the warrant requirement of the Fourth Amendment and evaluated the far-reaching privacy implications of DHS’ policy of allowing customs and border officials to seize and search the digital devices of international travelers without a warrant. “There are no statutory limits on who can see this information, how long it can be kept, or how it can be used, and there is no special protection provided for sensitive material, political material, client-attorney privilege, trade secrets, medical information, or materials otherwise privileged under the law,” Georgetown Law Professor Laura Donohue noted in her testimony. In April 2017, Dr. Paul joined U.S. Senator Ron Wyden (D-OR) in introducing the Protecting Data at the Border Act (S. 823) to stop this violation of Americans’ Fourth Amendment rights and prevent government officials from requiring Americans to disclose sensitive information on their digital lives in order to leave or re-enter the country. __________________________________________________ ________________"A politician will do almost anything to keep their job, even become a patriot" - HearstSpontaneous cerebrospinal fluid rhinorrhoea and pneumocephalus following temporal lobectomy for epilepsy. A 30-year-old female presented with headache, CSF rhinorrhoea, mild right facial weakness, 2 months following temporal lobectomy for epilepsy. CT revealed marked intraventricular pneumocephalus with breached air cells in the pneumatized lower part of temporal bone. The dural and bony defects repaired successfully with complete resolution of the pneumocephalus.Hasbro Reconstruction Hasbro Reconstruction was a 2016 comic book launch by IDW Publishing about its line of comic books based on properties of the toy company Hasbro. Since June 2016, this branding converged most of IDW's Hasbro comics into the Hasbro Comic Book Universe, using the end of Revolution as its launching pod, which then continued with First Strike. For November 2018, IDW concluded the branding. Background The Hasbro Reconstruction branding serves to converge IDW's own versions of Transformers and G.I. Joe into a shared universe of characters from various Hasbro brands, which had started with Simon Furman and E. J. Su's The Transformers: Infiltration in October 19, 2005. Rom and Micronauts reappeared on 2016 after Hasbro regained their comic book rights from Marvel Comics. Action Man and M.A.S.K. were the last additions for the event series Revolution. Between 2017 and 2018, the characters of Visionaries debuted on the aftermath of the event series First Strike. The Reconstruction branding concluded with the Transformers: Unicron miniseries. Titles Ongoing series One-shots See also List of comics based on Hasbro properties References Category:IDW Publishing Category:Comic book reboots Category:Hasbro Category:2016 comics debuts Category:2018 comics endings Category:Action Man Category:G.I. Joe comics Category:Rom the Spaceknight Category:Science fiction comics Category:Transformers comicsJustice Small-holder farmers deserve the right to choose improved seeds and modern agricultural practices that can improve their livelihoods and benefit their families. Anti-GMO activism has stalled the adoption of genetically engineered crops in many countries, contributing to the perpetuation of unsafe pesticide use, hunger, and poverty.The Story Behind Laos Buffalo Dairy In 2010, business commitments in Singapore brought our two families together for what would prove to be a very fortuitous meeting. After many years of either working for multi-national corporations or running our own companies, we (Susie, Steven, Rachel and Matt) discovered that we had complementary skill sets and were ready for a new adventure - aka a mid-life crisis with a purpose rather than a Porsche. In 2014 we moved to Luang Prabang in the heart of Laos and soon realized that in this land full of buffalo, a dairy industry was non-existent. Needless to say, this made finding good quality cheese very difficult. And we love our cheese! After some sleepless nights and much research, we came to the conclusion that we can do it ourselves and the local community could benefit in the process. To test the idea, a proof of concept was implemented, which is just a fancy way of saying "Let's all watch YouTube videos on milking, get hold of a buffalo and see what we can do". We rented 3 buffalo from Mr. Eh in Thin Keo Village, about 30-minutes outside of Luang Prabang town (Mr. Eh and family pictured above). While nobody in the area had ever seen a buffalo milked before, Mr. Eh gave us the chance to pilot the procedure. We milked the three buffalo every day for 6 weeks, invariably with quite an audience. We then brought the milk back to town and, as if by magic (and after a few initial tears :-) , our Chef, Rachel turned it into the first batch of truly delicious cheese. We then made our own mozzarella, ricotta, yogurt, ice cream and cheesecake, and shared our trial product line with local food suppliers, grocery stores, restaurants and friends. We were only asked one question: “When will you start?” Our first year was full of trials and tribulations trying to get the business up and running. It started with applying, and being approved for, 9 different government licenses, which was no easy feat. We held interviews for staff positions and hired 25 adventurous souls who were prepared to work with the crazy Falang (a friendly term for foreigners). Our veterinary consultant, Dr. Som, was trained in Cuban as a vet with 7 years of experience in the dairy business and speaks Lao, English, Spanish & French. He has been helping us from the beginning, with proper buffalo care, hosting information sessions with farmers in over 17 different villages, about milking, vaccinating and general care of buffalo plus training (and a few entertaining moments) on Artificial Insemination. After months of building and planting 15 hectares of Napier grass in preparation, on the 18th of July 2016 our first buffalo arrived, and the Laos Buffalo Dairy became the first of its kind in the country.Secure Checkout Personal information is secured with SSL technology. Free Shipping Free global shipping No minimum order. Description Learn how to apply kinesiology concepts and treat dysfunction with Muscolino’s Kinesiology: The Skeletal System and Muscle Function, 3rd Edition! With more than 1,200 full-color illustrations, this highly visual text offers a vividly illustrated look at the skeletal system and how muscles function as movers, antagonists, and stabilizers in the body. Part One covers the fundamentals of structure and motion, including essential terminology that is used in kinesiology. Part Two covers the skeletal system including the makeup of skeletal and fascial tissues. Part Three contains a detailed study of the joints of the body. And lastly, Part Four examines how muscles function. This new edition also boasts an all-new chapter on biomechanics, more than 100 online video clips, and an interactive muscle program. If you want a thorough understanding of muscle function and how to apply that knowledge on the job, then there’s no better guide than Muscolino! Key Features Coverage of strengthening exercises

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a kilo of_ skorpios _, scorpion fish, cleaned but left whole. It was a triumph. If you wish, you may substitute a combination of two red mullet, filleted; six large prawns; and 500 g (1 lb) of mixed mussels and clams – you can still follow the method below._ SERVES 4–6 Cook 3 potatoes, sliced, in a deep frying pan with light olive oil and add a very finely chopped onion; then add a glass of white wine and boil furiously, so that the alcohol evaporates. Add the pulp, minus seeds and skins, of 4 tomatoes, a teaspoon of hot paprika, a tablespoon of chopped parsley with the stalks, some black pepper and, if you wish, a teaspoon of tomato paste. Cover this with a lid and add a little hot water from the kettle, then simmer until the potatoes are completely soft. In a blender, add a chopped garlic clove to a little olive oil and blend to make a thick, pungent paste. Add this when your sauce is amalgamated and the potatoes are completely soft. Then place the fish on top of this mixture and poach them while the sauce reduces, so that the fish is moist and perfectly cooked, and stands a little proud of the sauce. Serve in deep, warm bowls. CHAPTER 5 WILD THINGS THE DEATH OF PAN _According to the first-century historian Plutarch, one night a boat was sailing through the dark, close to the island of Paxos; most of the passengers were still awake. Suddenly they heard a strange voice, which seemed to be coming over the water from the island. It called, 'Thamus!' 'Thamus!' – which was the name of the captain of the vessel. He remained silent and afraid; but it called again and again. Finally he answered and the voice said, 'Go to the harbour near Butrinto, and announce... that the Great Pan is dead.'_ _Thamus did as he was told (Butrinto is on the Albanian side of the Corfu channel, just north of Paxos) and immediately there was wailing of astonishment and grief from all who heard him. The news travelled fast to Rome, where Tiberius Caesar himself called Thamus to come before him. Pan, the god of animals and all wild things; Pan, the hoof-footed piper at the gates of dawn... all felt shocked and somehow bereft at the death of a god._ _But a hundred years later, when the Roman writer and scholar Pausanias toured Greece, he found that Pan's shrines and sacred caves were still visited and revered. And sometimes, when walking alone over the cliffs in the early morning, the sounds of hidden birds and a rustling through the trees make one fleetingly conscious – like a flash across one's peripheral vision – of the presence of something..._ _HORTA_ _Rumps in the air, bent deeply at the waist, women – from widows to very young girls – are to be seen all over the island of Paxos in March and April, gathering the first luscious green shoots of spring. The Greeks have a passion for all these bitter-sweet weeds, known as_ horta _. Electra and her two friends, both called Nitza, know by sight those which are good for salads or for cooking._ _The ancients loved peppery, bitter leaves and they searched out the bulbs of grape hyacinths, which stud the hillside with miniature patches of blue._ _Today's islanders love them too, adding spinach, chard, lovage and sorrel._ _Famine is within living memory. During the German occupation of Athens in the last war, an estimated 300,000 starved to death; their bodies were collected off the street each morning. So great was the hunger that the hills were stripped bare of wild greens... war-time was tough on the island, too. Today, when you see strapping teenagers towering above their tiny grandparents, you reflect on the dramatic change in diet._ Horta _are still treasured. They are free, growing abundantly on hillsides, at the cost of a little stooping to pick them, with no expensive imports by boat._ Radíkia _encompasses wild chicories, dandelions and all kinds of bitter leaves. Greeks cook the leaves and shoots of mallow; they look out for wood sorrel and field sorrel. They seize upon comfrey leaves, wild fennel and wild beets,_ vlíta. _Serve your weeds steamed, tossed in some good olive oil, with lemon tears and lemon zest; wilted, with a little minced garlic, or some olives; buttered, especially if you have spinach and chard, with mint; or chopped, ready for stuffing in pasta, in which case a generous grind of nutmeg would be splendid._ _Add chopped drained_ horta _to little pastry tarts, topped with olives, capers anchovies, béchamel or hollandaise... purists select the finest little leaves for a salad, with a few slices of radish or raw carrot, and droplets of cold-pressed extra-virgin olive oil._ WILD GREEN SOUP _This can be made from a basketful of leafy vegetables; or, very pleasingly, from the three witches that curse our gardens: nettles, dandelions and ground elder. Pick only the dainty young leaves of the nettles, young ground elder leaves and small dandelion leaves._ SERVES 4 150 g (5 oz) young nettle tops, dandelion leaves and ground elder; mixed with spinach or chard (optional) 2 tablespoons basmati rice 1 litre (1¾ pints/4 cups) vegetable or chicken stock 1 onion, peeled and finely chopped 2 leeks, trimmed, washed and finely sliced 2 stalks celery, chopped 50 g (2 oz) butter Greek yoghurt to serve fresh mint leaves to garnish sea salt and black pepper Wash the greens thoroughly, using rubber gloves when touching the nettles, and discard any tough stalks. Wash the rice to remove the starch and add to a pan with the chicken stock, then simmer until the grains of rice are soft. Sweat the onion, leek and celery in butter in a large frying pan; cover and allow to cook gently for 10 minutes, stirring occasionally, until soft, but do not allow it to brown. Add the rice and stock to the pan, bring it to a simmer and cook for a further 10 minutes. Then add the wild greens, stirring them as they wilt; simmer them until the rice and nettles are tender. Season with salt and plenty of pepper. Purée the soup in batches, re-heat – but do not allow it to boil. Serve in warm bowls with a swirl of yoghurt and a little chopped mint on top. Note: if kept too long, the bright green colour will be lost, so if you need to make this ahead, prepare till just before you add the greens, and cook them when you want to eat. FORAGING ON THE SHORE _In February, seemingly without fail, there are ten days of surprising warm weather. The sea is glassily calm; the balmy air suggests, deceptively, that spring has arrived. These are the_ alkionides meres _, the halcyon days – thanks to Alcyone, for whom Zeus had a passion. When his wife Hera found out, she changed Alcyone into a bird – and Zeus compassionately gave Alcyone ten days of calm weather, in which to lay her eggs... The Paxiots take advantage of this by going down to the seashore to gather limpets, snails and seaweeds._ _One seaweed is named_ oneira _– which means dream; these beautiful green and white weeds float just under the water. They use them for a salad with limpets, and some rice._ _The tiniest limpets are_ patales _– a great delicacy. They are pure gellified obstinacy to remove, so use the sharp tip of one shell as a lever to prise out the limpet, and swallow it raw, to taste the sea. There are cone-shaped limpets, too; their raw flesh is blended and eaten on top of fried rice._ SAMPHIRE _We in Britain are lucky enough to have samphire, as the Greeks do; why do so few appreciate it? It is my favourite wild food. Take a piece of plainly grilled fish, dressed in a little oil, with lemon juice and rock salt in which a few dried fragments of oregano have been pounded. Serve it with a warm dish of_ krìtamo _: tiny green stems of samphire that have been blanched very briefly, then anointed with a little lemon juice, the very best olive oil, and dressed with some 'tears' of lemon segments... a dish with an incredible depth of flavour._ _When preserved in white wine vinegar, samphire can be used in winter salads._ SNAILS _After winter hibernation, snails come out in the spring showers – and are promptly collected by young and old. They are fed only garden greens, to purge them, for a week. At Electra

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applied to newborn piglets, those receiving the highest score of 4 had lower blood pCO~2~, higher pH and lower lactate and glucose than those with the lowest liveborn score of 2 \[[@B11-animals-09-00885]\], indicating that they had suffered less birth asphyxia. In support of this, piglets with severe meconium staining (\>40% covering of the skin) recorded a lower viability score at birth \[[@B46-animals-09-00885]\]. Viability is important as locating the sow's udder and outcompeting littermates ensures access to colostrum/milk. Time taken for the piglet to reach the udder was reported to increase with increased pCO~2~ and blood lactate as well as with decreased pH \[[@B11-animals-09-00885]\]; meconium-stained piglets took twice as long to contact the sow's udder than unstained piglets \[[@B46-animals-09-00885]\]. Langendijk, et al. \[[@B12-animals-09-00885]\] showed that asphyxia impacted on the time it took a piglet to successfully feed and most importantly, the volume of colostrum ingested. Piglets with high lactate levels were slower to feed and took in less colostrum than those without evidence of asphyxia. The measurement of such behaviours is important given the link between colostrum intake and piglet survival \[[@B47-animals-09-00885]\]. Catecholamines are released to stimulate liver glycogenolysis after asphyxia \[[@B11-animals-09-00885]\]. Because of this, piglets that are asphyxiated \[[@B11-animals-09-00885],[@B32-animals-09-00885]\] and that die during the first ten days \[[@B48-animals-09-00885]\] display elevated blood glucose levels. So, taken collectively, asphyxiated piglets have lower vitality which will compromise feeding and mobilise glycogen stores at a rapid rate, making hypoglycaemia likely. Therefore, it is imperative to restore glucose levels in asphyxiated piglets immediately and employ colostrum management strategies such as those outlined by Alexopoulos, et al. \[[@B47-animals-09-00885]\]. Asphyxiated piglets also struggle with regards to temperature homeostasis. Heavily meconium-stained piglets recorded rectal temperatures 1.7 °C cooler at birth than those with little to no staining \[[@B46-animals-09-00885]\]. Rectal temperature at 24 h of age has also shown to increase with pH and with decreased pCO~2~ and lactate \[[@B11-animals-09-00885]\], and so the negative effect of birth trauma on temperature is maintained in the days following birth. However, Herpin, et al. \[[@B49-animals-09-00885]\] suggested that it is not homeothermy per se that is impaired in asphyxiated piglets, but rather the link between birth trauma, colostrum intake and carbohydrate metabolism (explored in the previous paragraph) that results in the low body temperature. Regardless, with reduced rectal temperature, these piglets are at increased risk of chilling. Thoresen, et al. \[[@B50-animals-09-00885]\] identified that secondary energy failure was reduced when piglets were cooled to 35 °C for 12 h after induced asphyxia, with this finding and others being responsible for the clinical application of therapeutic hypothermia for treatment of human neonatal hypoxic-ischemic encephalopathy. Thus, the commonly reported hypothermia in asphyxiated piglets may have neuroprotective effects. How to manage the rewarming event then becomes contentious. Wang, et al. \[[@B51-animals-09-00885]\] identified increased apoptosis when rewarming was rapid rather than slow (i.e., 2 h versus 8 h), and so a more gradual increase in body temperature of chilled piglets would result in the highest success rate. Given these impacts on a piglets ability to thermoregulate and ingest colostrum, perhaps it is not surprising that when no additional care is provided, mortality in the first week of life is doubled from 5.5% to almost 11% in asphyxiated piglets \[[@B12-animals-09-00885]\]. In addition to survival being reduced, piglet growth is compromised when birth trauma is experienced. When piglets are exposed to asphyxia, blood flow is reduced to the small and large intestines during the event, which resulted in intestinal lesions at 12 h of age \[[@B52-animals-09-00885]\]. Such damage to the gastro-intestinal tract would have ramifications for milk and colostrum absorption. Indeed, piglets with heavy meconium staining gained 168 g by day 5, compared with 520 g for control piglets \[[@B46-animals-09-00885]\]. By ten days of life, average daily gain (ADG) was shown to be inversely related to blood lactate levels at birth \[[@B11-animals-09-00885]\]. At weaning, ADG was reduced from 259 g/d to 245 g/d in least versus most asphyxiated piglets, respectively; from weaning to 10 weeks ADG was reduced from 721 g/d to 664 g/d in least versus most asphyxiated piglets, respectively \[[@B12-animals-09-00885]\]. From these studies, it is evident that asphyxiated piglets perform poorly with regards to growth not only in the farrowing house, but after the weaning event also. What is less clear is the mechanism behind the reduced growth rates. Is it simply that the less viable pigs ingested low colostrum levels (with colostrum intake influencing growth to six weeks of age \[[@B53-animals-09-00885]\]), or are there longer term impacts of asphyxia on the physiology and development of the pig? Ralph, et al. \[[@B54-animals-09-00885]\] demonstrated behavioural differences at the end of lactation (day 21) in piglets heavily stained with meconium suggestive of neurological shifts that persist outside the perinatal period. Further work examining whether there are long term gastro-intestinal changes in piglets experiencing asphyxia are warranted. 9. Conclusions {#sec9-animals-09-00885} ============== Using conservative estimates from this review, 10% of piglets are stillborn and 15% of those born alive are at an increased risk of significant morbidity and mortality from birth trauma. Assuming a total litter size of 15, this equates to 3--4 viable piglets per litter that will be affected by asphyxia, a figure that will only rise with increased prolificacy. The parturition process is almost exclusively responsible, with cumulative farrowing duration rather than birth interval explaining most of the damage to piglets. Interestingly, sows at risk of delivering asphyxiated piglets are already compromised before the expulsive phase. This means that interventions that are applied during the second phase when piglets are birthed will have little impact, and in some cases, may actually increase the odds of a dead or low-viability piglet. Asphyxiated piglets require special care immediately after birth as the condition impairs glucose and temperature homeostasis. Identifying ways to correctly manage the sow before parturition leading to a reduction in farrowing duration should be a priority in order to maximise piglet performance. P.L. and K.P. contributed equally to all aspects of this publication. This research received no external funding. The authors declare no conflict of interest. ![Distribution over different birthweight classes for stillborn piglets and liveborn piglets that survived to weaning (**left panel**) and neonatal mortalities and liveborn piglets that survived to weaning (**right panel**). The percentage on each Y-axis represents the percentage of piglets in each category (stillborn, neonatal mortalities, or liveborn piglets that survive to weaning) that fall into a particular birthweight class. In total, 1856 piglets were recorded (unpublished data). The data show that stillborn piglets and piglets that survive to weaning have a similar birthweight distribution, but that neonatal mortalities are skewed towards low birthweights.](animals-09-00885-g001){#animals-09-00885-f001} ![Effect of birth order on stillbirth (**left panel**) and measures of asphyxia (**right panel**) \[[@B12-animals-09-00885]\].](animals-09-00885-g002){#animals-09-00885-f002} You are here Find Special Collections materials Here is how you can do a basic search in SearchWorks to find all types of Special Collections materials: 1) Go to SearchWorks: http://searchworks.stanford.edu/ 2) Type in your search terms in the search box. Click on the word "search" 3) When the screen populates with your search results look at the left hand side and click on "location" 4) Select "Special Collections & Archives" as the location 5) The screen will populate with items found only in Special Collections and University Archives that match your search terms. From here you can refine your search even more by selecting format, author, publication year, etc. For example, if you wish to find archives of manuscript materials, you can limit format to "manuscript/archive" on the left hand side. Another way to search for archival or manuscript materials is to use search terms in the Online Archive of California and limit the institution to Stanford University on the right hand side. If you find a collection you

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canvas jacket. I have discovered something and I'm not sure what to do with it. It's possible there is a tie in with whatever it was Sandy was working on. But, as I said, I'm not sure how to proceed." "So why the questions?" "With Sandy, it was worry. I saw he was very worried when I spoke with him. And incredibly stressed. Probably drinking too much as a result. With you it's anger. It's very close to the surface and I'm not certain I should tell you any of what I have found." The urge to shake her hand off and walk away was immediate and powerful but she was right, the anger was too close to the surface. Frustration was keeping me wound up and in a state just below frenzy. I focused on those warm chocolate brown eyes and let the reassurance trickle in. Slowly my breathing relaxed and some of the tension eased out of my muscles. Her calm concern washed through me until I could take a breath without it catching. "Thanks." She gave my arm a gentle squeeze, a sad knowing smile on her face. "You tough guys are always a challenge." "Maybe not so tough." "No, definitely tough. I just wonder if you really realize just where that tough lives. But I digress. I do have things that need to be done. And one thing I feel should be done." "You've lost me there, Jill." She gave me a wry grin and walked over to the far corner of her office. She wheeled a cart with a TV and VCR on it so it faced the room. "Phillip, on Monday I was called in to treat a young woman. She hadn't gone to work and a coworker friend became concerned so she went to her apartment to check on her. The front door was unlocked and my patient was found huddled naked in the back corner of her closet. The friend called 911 when she couldn't get any response out of her. I understand things got pretty wild when a male paramedic tried to get her out of the closet." "Sounds like a response to a pretty brutal assault." "That's what the paramedics thought too. One was a woman and she managed to quiet the patient down to the point where she could be sedated. Once we got her on the wing I was able to give her an examination. She exhibited an unusual mix of symptoms. When no men were present she was almost catatonic in her responses but if she even glimpsed a man, she would become extremely agitated and display such violent behavior that we would have to physically restrain her." "Has she been able to communicate?" "Somewhat. Her mother lives in Winter Park and she came up to be with her daughter. With both the mother and I present I have been able to get her to talk but it has been very disjointed. Phil, we are talking about a very intelligent woman here. She was a paralegal in one of the more prominent law offices here in Jax. Very bright and personable." I nodded, wondering how it tied in with what I was working on. There was a strong mix of excitement and dread building inside me as my mind made a few minor quantum leaps. "Age?" "Twenty five." Attractive young professional woman, much like the two known victims. "You said you learned something. Something that needs to be dealt with." She nodded. "The physical examination I did showed she had been involved in fairly aggressive and rough sexual intercourse within 24 hours or so of admission. There is some bruising and scratching to indicate that. And the condition of her genitalia indicates that as well. Whoever she was with likes to play hard." "Abusively so?" Jill shrugged. "Not really. I've seen much worse." "Then why the strong reaction?" "At first I thought it could have been linked to her having a repressed nature prior to the incident. I interviewed her friend though and it appears she had been fairly normal in her sex life. If anything, she was aggressive. Dated quite a bit with no interest in settling down. I'm trying to contact some of her old boyfriends to see if I can get a better picture of what she was like but I don't think repressed is going to figure into it." It was becoming more obvious to me that Jill was more upset about this than I had previously noted. She was fidgeting with items on her desk as she spoke with me and the level of eye contact had dropped radically. "Jill? Have you reported this?" She looked at me and I was surprised at the haunted desperation in her face. "Reported what? There isn't enough evidence to prove assault. She wasn't beaten. And her friend said that other than being upset over another friend's disappearance about a month ago, she had seemed quite normal." Suddenly there were alarms going off in my head. It felt as if someone had grabbed my chest in a massive vise and cranked it for all they were worth. Jill saw the reaction and started. "What is it, Phil?" I waved her off impatiently. "So why did you call me?" "This morning I tried hypnosis. I had discussed it with her mother as a possible way of reaching past the block. I didn't think I would have much luck; you generally have to have some active participation with the patient to get them into a state where the suggestions work. I was wrong. As I said, she is a bright perceptive woman." She paused and met my eyes. "Her mother agreed to the idea just as she has agreed to letting you see the video tape I made of the session." "Has she seen it?" "God, no." I walked over and put my hands on her shoulders. She was trembling slightly, her eyes searching mine for some kind of reassurance. "Can you watch it again?" She shivered and closed her eyes. "I haven't stopped watching it. It keeps replaying in my head." I hugged her, pulling her close. I dreaded seeing whatever it was that had disturbed her so deeply but I knew I had to do it. "I can watch it alone." She shook her head. "No. I need to see it." She looked up at me. "Just hold my hand?" I let her go enough for her to reach the controls and get the thing started. Then she tucked herself under my arm as the screen came to life. I hadn't been prepared for the woman's appearance. Latino heritage was obvious in her dark hair, eyes and coloring but she was more than a little stunning. Even with the dulled vacuous expression and general disarray, there was a quality to her. Jill's voice was a soothing rhythm like flowing water, interrupted only slightly by the quiet monosyllabic responses from a slack mouth. It was eerie watching as the hypnosis took hold. The girl's name was Felice and at Jill's prompting, she seemed to come alive under deep hypnosis. Her mouth tightened into a smile that covered the slight overbite and dark limpid eyes took on a remembered sparkle. I could see why Jill didn't expect to find some quiet little mouse that had been afraid of sex in the woman's past. As the session took hold there was an aura, a vivacity that blossomed as Felice's natural persona came out of hiding. Jill's words guided her back to when her world had been safe and then began the journey into darkness. It was clear Felice had enjoyed her relationship with a man named Brian. Under different circumstances, her coquettish manner might have stirred the voyeur in me. It was almost like watching some kind of soft porn video as she spoke so seductively, bringing herself and her phantom lover to sensuous climax. Then suddenly, it changed. Terror flared in her eyes, her entire body went rigid as she fought to free herself from the grip of her lover. She began to scream in a hoarse guttural voice that made my throat ache in sympathy. Jill brought her back under control with some difficulty, almost forcing her back into the peace of forgetfulness. Jill reached a shaking hand over and pushed the stop button and then turned off the TV. "Did you catch what she said?" I nodded, the horror slowly settling in me. Felice's terror had struck a very primal chord in me. "Perro." "You know what it means?" "Spanish for dog." "Felice is first generation Cuban. Her parents escaped when Castro took over." I looked down at her, finally able to tear my eyes from the dark screen that still held the images of horror. It was burned into me beyond my retinas. Looking into Jill's eyes I could see it was the same for her. I hugged her, the embrace becoming fierce as we both tried to draw some comfort from the contact. "Jill, the tests you did. Did you find any physical evidence of her partner?" She nodded shortly against my chest, her arms clasping convulsively around me. "Some hair. And semen." I waited until the spasm passed with a confidence I already knew what her next words would be. "It wasn't human, Phil" She began to cry very quietly. I held her, a part of me wishing I had the

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is divided by a. 5 Let u be (-6)/((-5)/(220/8)). Suppose -6*c + u = -63. Calculate the remainder when c is divided by 9. 7 Calculate the remainder when 27 is divided by (-2)/11 + (2 - (-72)/33). 3 Let h = 27 - -31. What is the remainder when h is divided by 12? 10 Suppose -4*i - 14 + 4 = -5*u, -6 = -3*u + 5*i. Suppose 0 = -4*p + u*p + 36. What is the remainder when p is divided by 10? 8 Let m(j) = 19*j - 43. What is the remainder when 119 is divided by m(3)? 7 What is the remainder when -3 - ((-1)/(-5) + 964/(-20)) is divided by 11? 1 Suppose -4 = 5*y - 24. Suppose 4*j - 2 = 3*o + 12, -2*o = -j + 6. Calculate the remainder when 23 is divided by (8 - y)/((-1)/o). 7 Let y = 174 - 305. Let x = y - -188. Calculate the remainder when x is divided by 20. 17 Let p(g) = g**2 + 4. Let m be p(0). Suppose 5*k + m*c = k + 68, 61 = 3*k - 2*c. What is the remainder when 54 is divided by k? 16 Suppose -z - 5 = -41. Let t = z - -21. What is the remainder when t is divided by 20? 17 Let w(g) = -16*g - 29. Let f(o) = -5*o - 10. Let n(r) = 17*f(r) - 6*w(r). What is the remainder when n(5) is divided by 20? 19 Suppose 5*h - 80 = 20. Suppose 0 = -2*f - 2*f + h. What is the remainder when 13 is divided by f? 3 Let w(m) = m**3 + 5*m**2 - 2*m + 1. Calculate the remainder when 98 is divided by w(-4). 23 Let a(t) = 2*t + 2. Let b be a(2). Let n(i) = -i**3 + 5*i**2 + 7*i - 8. Let f be n(b). Calculate the remainder when 32 is divided by 112/10 + f/10. 10 Suppose 4*y = -y + 80. Let a = y + 9. Calculate the remainder when a is divided by 9. 7 Suppose -5*v + 69 = -46. Let f be -4*3/(-9)*3. Suppose -l + f = -4. Calculate the remainder when v is divided by l. 7 Suppose -3*p + 4*p - 15 = 0. What is the remainder when p is divided by 4? 3 Suppose -4*g - 3 = -43. Suppose -v + 6 = 2*v. Suppose -v*b - i = -24, 3*b + g*i - 29 = 5*i. What is the remainder when b is divided by 8? 5 Suppose g + 4*g = 5*w - 105, 3*w = 5*g + 73. Calculate the remainder when 29 is divided by w. 13 Suppose -4*i + 3*i = -5. Suppose 0 = 2*h - 0*h + 3*t - 12, i*t - 4 = 2*h. What is the remainder when h is divided by (-1)/2 - 25/(-10)? 1 Let u = 0 + -2. What is the remainder when 57 is divided by 360/27*(-3)/u? 17 Suppose 0 = -4*r + 6 + 2. Suppose -w + 98 = -5*t, -r*t - 2*t - w - 82 = 0. Let j = t + 33. Calculate the remainder when j is divided by 7. 6 Suppose -2*f + 60 = 2*g, -f + 4*g + 30 = -0*f. Let m = f - 24. What is the remainder when 9 is divided by m? 3 Let x(m) = -10*m - 17*m - 7 + 24*m. Calculate the remainder when 30 is divided by x(-6). 8 Let y be (-16)/88 - (-26)/22. What is the remainder when 4/y*330/40 is divided by 9? 6 Suppose 0*w + t = -4*w + 30, -5*w - t = -37. What is the remainder when 16 is divided by w? 2 Let y(a) = 8*a**2 + 2*a + 1. Let c be y(-1). Let d = c + -4. Suppose 0*h + 3*h - l - 24 = 0, d*h = -l + 30. Calculate the remainder when 16 is divided by h. 7 Suppose -4*i - 1 + 5 = 0. Let s be 4*1*1/i. Suppose -s*p + 16 = -0*p. What is the remainder when 10 is divided by p? 2 Let f = -6 + 4. Let h be (12/8)/((-1)/f). Suppose -h = -3*n + 6, -4*j - 3*n = -77. Calculate the remainder when 49 is divided by j. 15 Suppose 0*o - 3*o = -t, 0 = -o. Suppose -3*a + 4*v + 35 = -2*a, -4*a + 3*v + 192 = t. What is the remainder when a is divided by 13? 12 Suppose 0 = 2*h + h + 99. Let f = 46 + h. Calculate the remainder when f is divided by 8. 5 Let p = -3 + 65. Calculate the remainder when p is divided by 33. 29 Suppose 9*j - 51 = -8*j. Suppose 4*x - 32 = -g - 2*g, 3*g + 5*x - 34 = 0. What is the remainder when g is divided by j? 2 Suppose -2*n + 3*n = 27. Calculate the remainder when n is divided by (((-1)/3)/1)/(3/(-126)). 13 Suppose -3*y + 0*y = -3*i + 24, 0 = 4*y - 3*i + 33. Let z = y + 21. Let s = z + -7. Calculate the remainder when s is divided by 2. 1 Suppose 2*a + 10 = -0*a, -105 = 4*p + 5*a. What is the remainder when p/(-6) - 2/6 is divided by 1? 0 Calculate the remainder when (10/25)/(1/85) is divided by 12. 10 Suppose 8 = -4*t + 5*m, t + 0 = -2*m - 15. Let b = -44 - -123. What is the remainder when 21 is divided by b/7 + 2/t? 10 Let i(f) = -f**3 + 1 + 1 + 1. Let y(j) = -11*j - 36. What is the remainder when y(-4) is divided by i(0)? 2 Suppose 3*r + 46 = 169. What is the remainder when r is divided by 14? 13 Let z = -20 + 44. Calculate the remainder when z is divided by 13. 11 Let w(t) = -4*t - 3. Let k be w(-5). Let g = k + 28. Suppose -4*i + 107 - 15 = 0. What is the remainder when g is divided by i? 22 Suppose -3*r - u + 31 = 0, 5 = -4*r + 5*r - 5*u. What is the remainder when 27 is divided by r? 7 Let k(s) = 2*s - 2. Let i(o) = -3*o - 7. Let c be i(-5). Calculate the remainder when 35/2*c/5 is divided by k(6). 8 Suppose -2*o = -106 - 94. What is the remainder when o is divided by 34? 32 Let p(t) = t**3 + 7*t**2 - 7*t + 5. Let s(z) = 2*z + 6. Let f be s(-7). Let r be p(f). What is the remainder when (-4 - r)/((-1)/23) is divided by 12? 11 Let a(g) = g**3 - 6*g**2 + 2*g - 1. Let d be a(6). Suppose -5 = -5*k - 0. Let j = k + d. What is the remainder when 35 is divided by j? 11 Suppose 3*i + 125 = -2*i. Let c = -16 - i. Let o(x) = -x**3 +

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continent’s north-east. And to make it even worse, native animal populations drop wherever the cane toad spreads – due to competition for resources and also the fact that most predators who eat them get poisoned. When threatened, cane toads ooze white poison called bufotoxin from parotid glands on their backs. According to the Global Invasive Species Database, it’s been known to kill cats, dogs, snakes, lizards and even humans. There are programs to try and train animals away from eating cane toads, but Australian crows (Corvus orru) don’t need any of that. These birds have figured out how to get a meal and how not to get poisoned – and now an Australian nature photographer has captured a crow in action: “These clever birds have learnt to roll the toads onto their backs, sometimes doing so repeatedly if the luckless toad tries to hop away. Crows know which bits to eat – fleshy thighs, tongues, intestines – and how to get at these from below without contacting the lethal parts.” It’s probably more a testament to the crows’ cleverness than a solution to the cane toad conundrum.Customer reviews of our Photo Graduation Announcements May 11, 2015Take a close look "We ordered this card for our daughter's High School graduation. The cards printed beautifully, but make sure you look closely at the printed wording side to notice there are markings on the black background. We did not look closely enough and I thought they were smudges. The fault was mine for not looking closely enough, but the rest of the card is beautiful." January 27, 2014Beautiful Card "This was the perfect card at the right price! The pictures turned out great,& it was a very stylish more expensive looking card without the high cost. Love it!" June 12, 2013Great looking "The card looked great, I loved the layout and was overall happy with the quality. We were proud to send it out to family and friends."So, Here’s the “Why” In Tableau, we are easily able to slice and dice the data according to our dimensions thanks to the default manner in which Tableau aggregates the data on our behalf. Therefore, I can simply add any measure and trust the view is appropriate at that level; from an overview, down to the finest level of detail, Tableau aggregates accordingly. But what happens when we have aggregate data, and we need to re-aggregate? For instance, what if I want to categorize and then summarize my sales data at a higher level than what currently exists in my data? As indicated in the picture below, my sales data is actually down to the item level for each customers’ purchase. Let’s say I would like to classify purchasers based on the overall amount they have spent rather than by each individual transaction. I don’t currently have any dimension in the data set that categorizes these sales, but there are a few ways I can create a solution in Tableau. I could create a conditional filter, or perhaps a series of sets for each one of these categories, but each would only allow me to view one category at a time. Most likely, I would build a custom calculation to create a new dimension in Tableau. I decided to create the following calculated field. The following calculation gives me the result I’m looking for; or so I think. This calculation allows me to view the sales classification against the entire data set to see the proportion of all categories at one time, but I wouldn’t be able to view a customer level summary with this calculation because it is performing at the row level, which is per each item sold (added color for emphasis of applied calculation). Although I can view the classification for each item that was sold, I’m interested in what my customer’s total spending level is. For example, if you view Customer #1, the overall sales total just over $19k, but according to our calculation, the sales classification is being made for each item that Customer #1 has purchased, sometimes multiple items per order. “Just remove the Item and Order levels,” you say. Let’s see what happens as a result. Thankfully, and unfortunately in this case, Tableau is still properly applying our row level calculation according to each item every customer has purchased. So, why is there only two entries, and why is one entry over $18k and colored orange according to the $9,999 – $5,000 range? If you look carefully at the previous screen shot, Tableau has summed up all like classifications. We had three items for Customer #1, each item in the $9,999 – $5,000 range, totaling $18,624. The rest were all items at or below the $4,999 threshold. Not exactly the result we intended. The calculation is unable to roll up according to the Customer level. But wait…here’s the great news. We can once again utilize the power of extracts to help for this scenario! So, here’s the “HOW”… In order to fix this, we can create an extract and aggregate the data according to the level that we’re interested in (I hope now you’re now saying to yourself, “So that’s what that check box is for”). First, we simply hide all of the levels of detail that will interfere, or be of finer grain, than the level we are interested in, which happens to be Customer ID. Therefore, if we hide the Item and Order ID, Tableau will aggregate the sales to a higher level, allowing us to see sales by customer (I am hiding all of the unnecessary dimensions for simplicity of the example). From this point, we can create our Extract, making sure to “Aggregate data for visible dimensions.” Now, we can see our calculation applied to the Customer level. Now that our calculation is being applied in the manner in which we were hoping, we can use it more functionally across the data set to see a summary of our customers (below TOP) versus the Item level (below BOTTOM) which skews our summary results and show us every record (item) instead of looking at our customers. Please feel free to comment or email with any questions and/or suggestions on this post. Happy extracting!Martin Smith (figure skater) Martin Smith (born January 14, 1968) is a Canadian former competitive ice dancer. With Jo-Anne Borlase, he is the 1989 NHK Trophy bronze medalist, 1989 Skate America bronze medalist, and 1990 Canadian national champion. With Michelle McDonald, he won the 1991 Canadian national title. Career Early in his career, Smith skated in partnership with Melanie Cole. The two placed fourth at the 1986 World Junior Championships, which took place in December 1985 in Sarajevo, and won the Canadian national junior title the same season. The following season, they competed on the senior level, placing 8th at the 1986 Skate America. In 1987, Smith teamed up with Jo-Anne Borlase. In their second season together, they won bronze at the Canadian Championships. In their third, they took bronze at the 1989 Skate America and 1989 NHK Trophy before winning the national title. They finished 7th at their final event together, the 1990 World Championships in Halifax, Nova Scotia. Smith competed the next two seasons with Michelle McDonald. The two won the 1991 Canadian national title but dropped to third in 1992 and missed out on the Olympics. Smith represented the Kitchener-Waterloo Skating Club (1986) and the Granite Club (1990 to 1992). Competitive highlights With McDonald With Borlase With Cole References Category:Living people Category:Canadian male ice dancers Category:1968 births--! qt:dataset:alltypesorc set hive.explain.user=false; SET hive.vectorized.execution.enabled=true; SET hive.auto.convert.join=true; SET hive.vectorized.execution.mapjoin.native.enabled=true; set hive.fetch.task.conversion=none; -- Using cint and cstring1 in test queries create table small_alltypesorc1a_n1 as select * from alltypesorc where cint is not null and cstring1 is not null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc2a_n1 as select * from alltypesorc where cint is null and cstring1 is not null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc3a_n1 as select * from alltypesorc where cint is not null and cstring1 is null order by ctinyint, csmallint, cint, cbigint, cfloat, cdouble, cstring1, cstring2, ctimestamp1, ctimestamp2, cboolean1, cboolean2 limit 5; create table small_alltypesorc4a_n1 as select * from alltypesorc where cint is null and cstring1 is null order by ctinyint, csmallint, c

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にシェアを取ってしまい、ひっくり返すことができなかったことからの教訓と言えるだろう。また、政策としてできることとして、とくに中～小規模企業に対するローカライズ支援策（翻訳支援や現地提携企業情報の提供など）を挙げた。ただ、この項は、アイデアが共通しているだけでは著作権による保護を受けることはできず、ある地域（仮にAとする）で最初にサービスインしたタイトル（仮に1とする）がいわゆる“元祖”と受け取られ、他地域（Bとする）でそのタイトル（1）より先にサービスインしたタイトル（仮に2とする）であっても、Aに後から2が参入した場合、どれを“元祖”、どれを“模倣”と捉えるか、あからさまにデータをコピーしている場合でもないかぎり、定義付けが難しい問題ではないかと感じられた。プレミアムフライデーによる経済効果の測定 2017年2月よりスタートしたプレミアムフライデーの効果がスマートフォンゲームアプリ業界でどのように現れているのかを検証した。ランキング上位50タイトルを対象に測定した結果、プレミアムフライデー実施後、売り上げの増加がみられた。野球の観戦者や旅行需要での効果はみられていないが、会社を退社した後、家や外でスマートフォンゲームアプリを遊ぶユーザーが増えたということになる。コンプガチャ規制の政策評価消費者庁の見解による景品表示法の“絵合わせ”にあたるとして、2012年5月に実質禁止されたいわゆる“コンプガチャ（コンプリートガチャ）”。この政策がどのように効果が及んだかを検証したもの。フリーミアムゲームの中で、コンプガチャを実施していたゲーム、通常のガチャを実施していたゲーム、ガチャのないゲームと売り上げとダウンロード数を検証していった結果、コンプガチャの実施/非実施を問わず、ガチャを実施していたゲームの売り上げ/ダウンロード数ともに低下したという結果となった。政策はコンプガチャのみに作用することが望ましかったが、結果はガチャ全般のイメージが悪化し、一時的なゲーム離れを起こしたのみで終わったと考えられるという結果となった。山口真一氏の講演国際大学グローバル・コミュニケーション・センター講師の山口真一氏。 “課金疲れ”の検証：モバイルゲームにおいて、長期に売り上げを最大化する最適APPUはいくらか？モバイルゲームにおいて、KPI（Key Performance Indicators＝目標を達成するための施策がうまくいっているかを確認するための指標）として、“アクティブユーザー数（AU)”、“有料ユーザー数”、“有料ユーザーひとり当たりの単価（ARPPU）”を用いていることが多い。短期の売上高を最大化するには、これらをいかに上げるかを考えればいいが、ヒアリング調査によると、高額を支払ったユーザーがつぎの月に購入を控えるようになったり、サービス自体から離脱するといった行動＝“課金疲れ”がみられることがわかった。これを踏まえた、長期売上高を最大にする最適ARPPUが存在するのではないかという検証が行われた。 2012年9月～2015年4月の182のゲームを対象に得られたパネルデータを分析に用いた結果、前期の消費者支払い行動の集計であるARPPUが売り上げに影響を与えているということがわかったほか、前期の無料ユーザーが増えると今期の売り上げが増加する＝有料ユーザーへの移行がみられるため、単なるコストではなく売り上げに貢献していることや、サービスが長期化すると売り上げは下がっていくこと、2月、9月、10月は売り上げが低く、8月が高い（＝夏休み需要？）といったデータがみられた。また、ARPPUが11754円を超えると売り上げは逆に下がっていく＝“課金疲れ”が見られる結果となった。長期売上高最大化のためには、短期的に売り上げを追い求めるだけでなく、ARPPUを上げすぎない戦略を考える必要があるという結論となった。モバイルゲームがコンソールゲームに与えている代替効果は大きいのか？モバイルゲームの台頭がコンソールゲームを代替し、パラダイムシフトが起きているというが、その効果はどれぐらい大きいのかを検証。ゲームエイジ総研の2014年8月～2015年8月に行われた50000人のアンケート調査データを用いており、据え置き機ではプレイステーション3、Wii、PSP、ニンテンドー3DSをメインとした分析を行った。 PS3→PS4、Wii→Wii U、PSP→プレイステーション Vitaといったゲーム専用機の後継機では代替効果が大きく、携帯ゲーム機と据え置き型ゲーム機での効果は限定的であることが改めて明らかになったほか、スマートデバイスの代替効果については、任天堂ハードと、ソニー・インタラクティブエンタテインメントのハードではユーザー層の違いから代替効果に違いが出た。さらに、据え置き型ゲーム機と携帯型ゲーム機では効果

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grandmother was a Parkinson. Some things I learnt from her— 'The girl known as Mary Jordan was in our service. She had connections in the Navy—her mother was Austrian and so she herself spoke German fluently. 'As you may know, and as your husband certainly knows already, there are certain documents which will shortly be released for publication. 'The present trend of political thinking is that hush-hush, necessary as it is at certain times, should not be preserved indefinitely. There are things in the records that should be made known as a definite part of our country's past history. 'Three or four volumes are due to be published within the next couple of years authenticated by documentary evidence. 'What went on in the neighbourhood of Swallow's Nest (that was the name of your present house at that time) will certainly be included. 'There were leakages—as always there are leakages in times of war, or preceding a probable outbreak of war. 'There were politicians who had prestige and who were thought of very highly. There were one or two leading journalists who had enormous influence and used it unwisely. There were men even before the First World War who were intriguing against their own country. After that war there were young men who graduated from universities and who were fervent believers and often active members of the Communist Party without anyone knowing of that fact. And even more dangerous, Fascism was coming into favour with a full progressive programme of eventual union with Hitler, posing as a Lover of Peace and thereby bringing about a quick end to the war. 'And so on. A Continuous Behind the Scenes Picture. It has happened before in history. Doubtless it will always happen: a Fifth Column that is both active and dangerous, run by those who believed in it—as well as those who sought financial gain, those who aimed at eventual power being placed in their hands in the future. Some of this will make interesting reading. How often has the same phrase been uttered in all good faith: Old B.? A traitor? Nonsense. Last man in the world! Absolutely trustworthy! 'The complete confidence trick. The old, old story. Always on the same lines. 'In the commercial world, in the Services, in political life. Always a man with an honest face—a fellow you can't help liking and trusting. Beyond suspicion. "The last man in the world". Etc., etc., etc. Someone who's a natural for the job, like the man who can sell you a gold brick outside the Ritz. 'Your present village, Mrs Beresford, became the headquarters of a certain group just before the First World War. It was such a nice old-world village—nice people had always lived there—all patriotic, doing different kinds of war work. A good naval harbour—a good-looking young Naval commander—came of a good family, father had been an admiral. A good doctor practising there—much loved by all his patients—they enjoyed confiding their troubles to him. Just in general practice—hardly anyone knew that he had had a special training in chemical warfare—in poison-gases. 'And later, before the Second World War, Mr Kane—spelt with a K—lived in a pretty thatched cottage by the harbour and had a particular political creed—not Fascist—oh no! Just Peace before Everything to save the world—a creed rapidly gaining a following on the Continent and in numerous other countries abroad. 'None of that is what you really want to know, Mrs Beresford—but you've got to realize the background first, a very carefully contrived one. That's where Mary Jordan was sent to find out, if she could, just what was going on. 'She was born before my time. I admired the work she had done for us when I heard the story of it—and I would have liked to have known her—she obviously had character and personality. 'Mary was her own Christian name though she was always known as Molly. She did good work. It was a tragedy she should die so young.' Tuppence had been looking up to the wall at a picture which for some reason looked familiar. It was a mere sketch of a boy's head. 'Is that—surely—' 'Yes,' said Mr Robinson. 'That's the boy Alexander Parkinson. He was only eleven then. He was a grandson of a great-aunt of mine. That's how Molly went to the Parkinsons' in the role of a nursery governess. It seemed a good safe observation post. One wouldn't ever have thought—' he broke off, 'what would come of it.' 'It wasn't—one of the Parkinsons?' asked Tuppence. 'Oh no, my dear. I understand that the Parkinsons were not involved in any way. But there were others—guests and friends—staying in the house that night. The evening in question was the date of a census return. The names of everyone sleeping under that roof had to be entered as well as the usual occupants. One of those names linked up in a significant manner. The daughter of the local doctor about whom I have just told you came down to visit her father as she often did and asked the Parkinsons to put her up that night as she had brought two friends with her. Those friends were all right—but later her father was found to be heavily involved in all that was going on in that part of the world. She herself, it seemed, had helped the Parkinsons in garden work some weeks earlier and was responsible for foxgloves and spinach being planted in close proximity. It was she who had taken the mixture of leaves to the kitchen on the fatal day. The illness of all the participants of the meal passed off as one of those unfortunate mistakes that happen sometimes. The doctor explained he had known such a thing happen before. His evidence at the inquest resulted in a verdict of Misadventure. The fact that a cocktail glass had been swept off a table and smashed by accident that same night attracted no attention. 'Perhaps, Mrs Beresford, you would be interested to know that history might have repeated itself. You were shot at from a clump of pampas grass, and later the lady calling herself Miss Mullins tried to add poison to your coffee cup. I understand she is actually a granddaughter or great-niece of the original criminal doctor, and before the Second World War she was a disciple of Jonathan Kane. That's how Crispin knew of her, of course. And your dog definitely disapproved of her and took prompt action. Indeed we now know that it was she who coshed old Isaac. 'We now have to consider an even more sinister character. The genial kindly doctor was idolized by everyone in the place, but it seems most probable on the evidence that it was the doctor who was responsible for Mary Jordan's death, though at the time no one would have believed it. He had wide scientific interests, and expert knowledge of poisons and did pioneering work in bacteriology. It has taken sixty years before the facts have become known. Only Alexander Parkinson, a schoolboy at the time, began having ideas.' ' _Mary Jordan did not die naturally,_ ' quoted Tuppence softly. ' _It must have been one of us._ ' She asked: 'Was it the doctor who found out what Mary was doing?' 'No. The doctor had not suspected. But somebody had. Up till then she had been completely successful. The Naval commander had worked with her as planned. The information she passed to him was genuine and he didn't realize that it was mainly stuff that didn't matter—though it had been made to sound important. So-called Naval plans and secrets which he passed to her, she duly delivered on her days off in London, obeying instructions as to when and where. Queen Mary's Garden in Regent's Park was one, I believe—and the Peter Pan statue in Kensington Gardens was another. We learned a good deal from these meetings and the minor officials in certain embassies concerned. 'But all that's in the past, Mrs Beresford, long, long in the past.' Colonel Pikeaway coughed and suddenly took over. 'But history repeats itself, Mrs Beresford. Everyone learns that sooner or later. A nucleus recently reformed in Hollowquay. People who knew about it set things up again. Perhaps that's why Miss Mullins returned. Certain hiding-places were used again. Secret meetings took place. Once more money became significant—where it came from, where it went to. Mr Robinson here was called in. And then our old friend Beresford came along and started giving me some very interesting information. It fitted in with what we had already suspected. Background scenery, being set up in anticipation. A future being prepared to be controlled and run by one particular political figure in this country. A man with a certain reputation and making more converts and followers every day. The Confidence Trick in action once again. Man of Great Integrity—Lover of Peace. Not Fascism—oh no! Just something that looks like Fascism. Peace for all—and financial rewards to those who cooperate.' 'Do you mean it's still going on?' Tuppence's eyes opened wide. 'Well, we know more or less all we want and need to know now. And that's partly because of what you two have contributed—the operation of a surgical nature on a rocking-horse was particularly informative—' 'Mathilde!' exclaimed Tuppence. 'I _am_ glad! I can hardly

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Find the second derivative of x(t) wrt t. 60*t**3 - 96*t + 4 Let u(g) = 138 + 0 + 207*g - 440*g. Let m(j) = -228*j + 139. Let h(n) = 3*m(n) - 4*u(n). Differentiate h(s) with respect to s. 248 Let l = 136 - 62. Let t = 76 - l. What is the first derivative of 5*c**t + 10*c**2 - 14 - 2*c**2 + 11*c**2 wrt c? 48*c Let c = 37 - 35. Find the third derivative of -1330*b**5 + 96*b**c + 672*b**5 + 669*b**5 wrt b. 660*b**2 Let h be 0/((6 - -4)*-1). Let z(o) be the second derivative of -6*o + h - 11/6*o**3 - 11*o**2. What is the first derivative of z(r) wrt r? -11 Let j = -69 + 74. Suppose 5*o + 25 = j*i, 0 = 8*i - 3*i + 3*o - 1. Find the third derivative of 2*x**6 + 23*x**6 - 10*x**2 - 4*x**2 + x**i wrt x. 3000*x**3 Let v(u) be the first derivative of 47 - 41*u - 1/2*u**2 - 23*u**3. Find the second derivative of v(j) wrt j. -138 Let p(v) = 5862*v**2 + 3614. Let z(o) = 43966*o**2 + 27113. Let r(a) = -38*p(a) + 5*z(a). Find the first derivative of r(d) wrt d. -5852*d Let h(g) be the first derivative of 103*g**6/30 + 15*g**3/2 - 86*g + 11. Let b(a) be the first derivative of h(a). What is the second derivative of b(n) wrt n? 1236*n**2 Suppose 32*d = 31*d. Suppose n + 1 - 19 = d. What is the second derivative of -237*f**4 + 222*f**4 + f - n*f wrt f? -180*f**2 Suppose -10*p = -19*p + 27. Find the third derivative of 17*o**5 - 15*o**3 - 14*o**2 + 10*o**p + 7*o**3 wrt o. 1020*o**2 + 12 Suppose 0 = v - 2*k - 6, -4*v - k - 4*k = -24. Find the third derivative of 4385*f - 4385*f - v - 3*f**2 - 22*f**5 wrt f. -1320*f**2 Let r(o) be the first derivative of 4066*o**3/3 - 3*o**2 + 222*o + 7135. What is the second derivative of r(t) wrt t? 8132 Let n(a) be the first derivative of 5063*a**3/3 + 3179*a + 589. What is the derivative of n(w) wrt w? 10126*w Let x(o) = -o**2 + 11*o + 7. Let y be x(12). Let j be 22/6 + y/((-30)/(-4)). Find the third derivative of 20*k**j + 17*k**3 - 25*k**5 - 37*k**3 - 34*k**2 wrt k. -1500*k**2 Find the second derivative of -29*p**3 + 45*p**3 - 16*p**3 - 544*p - 253*p**4 - 1908*p wrt p. -3036*p**2 Let m(z) be the first derivative of -2*z**5/5 - 53*z**4/4 + 10*z**3/3 - 1008*z**2 + 468. Find the second derivative of m(v) wrt v. -24*v**2 - 318*v + 20 Suppose 0 = -3*r - 3*w, -2*w + 3*w = -5*r. What is the second derivative of 72*g**2 + 34 - 8*g + r*g + 6*g + 0*g wrt g? 144 Let h(v) be the second derivative of -7/2*v**2 - 85*v + 0*v**3 - 2 - 17/3*v**4. Differentiate h(t) wrt t. -136*t Let a = 30 + -28. Suppose -7*w + a*w = -5*o - 545, -4*w + 2*o = -438. Find the second derivative of -2 - w*z**4 + 11*z + 2 + 119*z**4 wrt z. 108*z**2 Let l(z) = -33*z**4 - 15*z**2 + 122*z - 54. Let u(p) = -16*p**4 - 6*p**2 + 60*p - 27. Let h(f) = 5*l(f) - 9*u(f). Find the second derivative of h(r) wrt r. -252*r**2 - 42 What is the third derivative of -646*x**2 + 524*x**2 - 1439*x**2 + 1155*x**5 + 215*x**5 wrt x? 82200*x**2 Let z(r) be the first derivative of -6131*r**5/5 - 5622*r + 4489. Differentiate z(f) with respect to f. -24524*f**3 Let g be (-1*4/14)/(1/(-49)). Suppose -g = 6*v - 13*v. Differentiate -73*h**2 + 37*h**v + 41 - 39*h**3 + 36*h**2 wrt h. -117*h**2 Let l(b) be the third derivative of -152*b**7/105 - 131*b**5/60 - b**3 - 691*b**2. Find the third derivative of l(h) wrt h. -7296*h Suppose 4*l = y + 27 - 8, 12 = -4*y. Suppose -26 = -l*r - 18. Find the third derivative of 30 + 12*t**r - 7*t**6 - 30 wrt t. -840*t**3 Let f(i) = -i. Let b(t) = -8*t + 8. Suppose -2*g + 9 = -g + 3*n, 2*g = -4*n + 14. Let q(j) = g*f(j) + b(j). Differentiate q(o) wrt o. -11 Let p(c) be the third derivative of -989*c**5/60 - c**4/8 - 103*c**3/3 + 1478*c**2. What is the second derivative of p(w) wrt w? -1978 Let m be -29*2/(-10) + (-117)/(-585). Find the third derivative of -250*q**m - 5*q + 5*q + 290*q**6 + 141*q**2 wrt q. 4800*q**3 Let l = 721 + -595. What is the derivative of -2184*y + 4440*y + l - 2217*y wrt y? 39 Let l(s) = 25*s**2 - 18*s - 1770. Let x(p) = -24*p**2 + 19*p + 1767. Let b(v) = -7*l(v) - 6*x(v). Differentiate b(r) wrt r. -62*r + 12 Let s(c) be the first derivative of -7/2*c**2 + 11 + 0*c - 2/3*c**3. Let n(g) = g**2. Let x(q) = -3*n(q) + s(q). Find the second derivative of x(d) wrt d. -10 Let n(x) be the second derivative of -x - 13/4*x**4 - 4 + 0*x**2 - 21/10*x**5 + 0*x**3. What is the third derivative of n(f) wrt f? -252 Let l(v) be the first derivative of 15*v**5 + 0*v**3 + 120 + 0*v**4 - 39/2*v**2 + 0*v. Find the second derivative of l(m) wrt m. 900*m**2 Let l(r) be the first

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with the help of two guinea pigs - one real, one robotic. Chip 'n Dale Rescue Rangers: Volume 2 DVD DISC 1 Chip and Dale find themselves in the middle of a messy crime in which their police friends are falsely accused. Using the tricks they've learned from careful study of police-work, it's up to them to ensure justice and retrieve a stolen ruby from Fat Cat With all five crime-fighters together at last, the pursuit of Fat Cat and his evil owner, Claudaine, kicks into high gear. Meanwhile, Professor Nimnul makes things more complicated for the gang, who are forced to battle the elements. In Hawaii, the Rangers find themselves mixed up in the initiation of a new queen who happens to look just like Gadget. The queen-to-be tricks Gadget into taking her place in some dangerous royal hazing. DISC 1 1. "Catteries Not Included" (22:43) (Originally aired March 6, 1989) The search for a missing kitten named Spunky leads the gang to an underground operation where robotic dogs are terrorizing dark alleys and kidnapping cats for Professor Nimnul. 2. "Three Men and a Booby" (22:44) (Originally aired April 30, 1989) A grocery store visit brings the gang face to face with a distressed purple booby (that's a bird), who's desperately trying to find her baby egg. The trail takes the Rescue Rangers to a grouchy little man named Mr. Humpty. 3. "The Carpetsnaggers" (22:46) (Originally aired May 7, 1989) 4. "Piratsy Under the Seas" (22:40) (Originally aired March 5, 1989) Dale's disregard for tidiness leaves him in the back of a garbage truck. When the rest of the gang attempts to rescue him, they wind up afloat on a junk barge. Not long after, they encounter a band of pirates in possession of a tidy treasure. In pursuit of Fat Cat and the legendary Maltese Mouse, Chip and Dale wreck the treehouse of a squirrel family. To make up for it, they agree to babysit the two squirrel children while their mother takes care of the place. Teenaged Tammy's unrequited crush for Chip has her running off to the city, throwing the Rescue Rangers among Fat Cat's crowd and forcing Chip and Dale to perform in drag! 6. "Flash the Wonder Dog" (22:44) (Originally aired March 19, 1989) To bring down beloved television star Flash the Wonder Dog, Fat Cat and his henchmen dress up in his costume and perform random acts of badness. Soon, the town is buzzing with bad vibes for Flash and the studio is replacing the canine with his cockatoo sidekick. Meanwhile, Dale gets a sobering meeting with his TV hero. The Rescue Rangers become involved in a bit of domestic drama when they encounter Roger Baskerville, a snooty mansion resident who wants nothing to do with his brother and his sheepdog, the rightful owners of the estate. Every turn seems to remind Chip of the literary adventures of the crafty detective Sureluck Jones and he uses his knowledge to try to outwit Baskerville and save the sheepdog. Monterey Jack's world-traveling father Cheddarhead Charlie stops by and helps the Rescue Rangers as they try to figure out a dining oddity at a seafood joint. Their trail leads them to Fat Cat and another evil plan. 9. "Risky Beesness" (22:44) (Originally aired April 23, 1989) A queen bee is quite perturbed when her entire swarm simply disappears. An enchanted Zipper and the rest of the Rescue Rangers are her only hope, and they track the bees down to an extermination company worker with dreams of rocking and rolling. DISC 2 10. "Bearing Up Baby" (22:42) (Originally aired May 14, 1989) The Rescue Rangers go vacationing in the woods. A little boy named Jeremy ditches his parents and befriends "fuzzies" small (the Rescue Rangers) and big (playful brown bear Humphrey) alike. His father isn't quite as charmed by the boy's new pal and leads a search party to hunt the large bear. 11. "Out to Launch" (22:46) (Originally aired March 26, 1989) The Rescue Rangers' exploration of a space station leads to big time adventure when Chip and Dale get launched into orbit while inside an astronaut suit. Soon, they get a first-hand look at outer space when they fall out of the shuttle. 12. "Dale Beside Himself" (22:48) (Originally aired March 12, 1989) An Earth-loving, shape-shifting alien makes himself look exactly like Dale. Having a powerful clone makes everyday tasks easier for the goofy chipmunk, but the aliens wears out his welcome when he tries to replace Dale. 13. "Kiwi's Big Adventure" (22:46) (Originally aired April 2, 1989) The kiwis, a tribe of primitive birds, steal the Rescue Rangers' plane but can't figure out how it works. The Rangers' attempts to retrieve the plane include a little jealousy and a lot of coddling when Dale "stubs his toe" and Gadget nurses him to an extreme. 14. "A Lad in a Lamp" (22:45) (Originally aired October 3, 1989) Monterey Jack happens upon Aladdin's magic lamp, but his newfound power irritates his friends and his third wish leaves him at the genie bound to serving the lamp's new masters: Fat Cat and his cronies. 15. "Battle of the Bulge" (22:40) (Originally aired October 9, 1989) After his appetite nearly gets him caught, Monterey Jack vows to diet and exercise. Meanwhile, the Rangers trace a series of heists marked by seedy remains back to Fat Cat and his new hired help, a trio of Jamaican fruit bats. 16. "Ghost of a Chance" (22:38) (Originally aired October 10, 1989) Fat Cat and his henchmen plan to steal the crown jewels of England, but the Rescue Rangers are there to try to stop them. While in the Tower of London, Monterey Jack discovers his brave ancestor Sir Colby was really a coward -- the mouse's ghost is no different and, suddenly, neither is Monty himself. The Rescue Rangers' day at the zoo ends with them picking up the case of the missing peanuts. After widespread interrogations, though, Chip and Dale are the prime suspects with the perturbed elephants and monkeys. But might the suspicious behavior of a couple of homesick Asian pandas be a lead? The Rescue Rangers go out for a night at the movies, only it turns out to be a night at the opera, which turns out to be a chance for gang to live up to their name when they encounter Sewernose de Bergerac, an envy-filled crocodile with a penchant for hand puppets. When the croc tries to sabotage the stage, the Rangers respond in appropriately theatrical fashion. DISC 3 19. "The Luck Stops Here" (22:41) (Originally aired October 6, 1989) Gadget falls into the possession of Clyde Cosgrove, a highly superstitious inventor who decides that the lavender-clad mouse is his new good luck charm. Gadget must overcome Cosgrove's vengeful cat and the nutty experimenter's high stress efforts to make a splash at a quickly approaching kitchen appliance convention. Feeling small and helpless, Zipper's self-confidence gets a boost when he is inadvertently among a group of pill bugs that Professor Nimnul zaps with his Gigantico Ray gun. While Nimnul uses the now-enormous pill bugs to convince mankind that demanding aliens in search of gold are among them, the bigger and buffer Zipper wows his fellow Rescue Rangers and tries to thwart the Professor's plans. A young boy's missing toy train doesn't warrant much attention from the police, but it does garner the Rescue Rangers' efforts. They discover the train is part of a bank-robbing scheme concocted by . . . Fat Cat, who else? 22. "The Case of the Cola Cult" (22:51) (Originally aired October 17, 1989) Fate brings the Rescue Rangers into contact with the Cola Cult, a group of rodents who worship a bright, catchy, musical commercial for Koo-Koo Cola and christen themselves with fruit soda of the same brand. When Gadget experiences some problems, she considers turning to them, until she learns the truth about one of their leaders. Not only is this likely the weirdest "Rescue Rangers" episode ever made, it could be the strangest half-hour of animation ever. That puts it in the same league as the giant crossover anti-drug special "Cartoon All-Stars to the Rescue." Good luck getting that Koo-Koo Cola jingle out of your head. The short, bearded, and greedy archaeologist Dr. Wexler steals a jeweled ring from King Nut-Ahn-Kahmen's tomb expecting diamonds. This theft sets the Egyptian tomb's guardian mummy Hiram

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187, 2214, 841, 2175, 13, 359, 908, 247, 374, 21865, 1982, 5149, 19693, 247, 1740, 14, 16441, 10541, 12948, 948, 8287, 247, 41381, 30116, 4438, 285, 1907, 271, 16432, 273, 337, 15, 26, 13, 253, 4869, 4758, 2130, 327, 247, 3382, 6979, 3943, 15, 733, 310, 417, 2590, 1880, 2074, 2538, 812, 2826, 387, 16432, 2193, 1679, 685, 337, 15, 26, 15, 187, 187, 688, 6452, 13, 374, 21865, 1982, 342, 271, 16432, 273, 337, 15, 26, 285, 337, 6, 12551, 1988, 12059, 22170, 285 ]

in vivo* as well, atherosclerotic lesions may be at risk during US imaging. Optison, in conjunction with US, has been used for gene therapy, drug delivery, angiogenesis studies, imaging vascular injury and evaluating cardiac function. As with any therapy, there are often untoward effects that need to be balanced the potential benefits. Given that there is the potential for widespread collateral effects, preclinical evaluation of ultrasound contrast agents is warranted which is consistent with the results presented in Figures [3](#F3){ref-type="fig"}, [5](#F5){ref-type="fig"}, [6](#F6){ref-type="fig"} and [7](#F7){ref-type="fig"}. The goal of US directed gene therapy is to identify and transfect selected anatomical structures with the gene(s) of interest. Vascular beds are ideal targets given the relative ease in identification and the delivery of the DNA of interest to the relevant tissues. The transfer of genetic material such as plasmid into a cell requires the brief disruption of the membrane. Additionally, signaling pathways such as ERK are activated and may play a role in the eventual expression of the transfected DNA, probably through mechanical sensing via integrins. US activates ERK ½ signaling via rock in skin fibroblasts \[[@B18]\]. Both endothelial cells and smooth muscle cells can be transfected with plasmids by Optison and US \[[@B19]\]. C-myc expression was decreased following transfection with anti-sense morpholino oligomers in porcine arteries treated *ex vivo*\[[@B20]\]. Neointimal proliferation was inhibited following balloon injury when anti-sense p53 plasmids or decoy E2F decoy oligo nucleotides, Optison and ultrasound were used to transfect rat carotid arteries \[[@B21],[@B22]\]. The contractile response to prostaglandin was reduced in porcine carotid arteries that were transfected with eNOS *ex vivo*\[[@B23]\]. Plasmid DNA and viruses can be transduced into skeletal muscle through an intra vascular route using US and US contrast agents \[[@B24]\]. In sum, the use of both Optison and US enhances the nonviral gene transfer is an alternative to using viral vectors \[[@B25]\]. While these studies focused upon transfer of genetic material, there was no attempt to evaluate untoward thrombus formation. Inflamed endothelial cells express cell adhesion molecules such as Intracellular adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM). Both ICAM and VCAM can be used to image inflammation and the inflamed tissue can be targeted for *in vivo* drug delivery as well. A gas-filled microbubble with anti-ICAM-1 antibody on its shell specifically binds to activated endothelial cells over expressing ICAM-1 \[[@B26]\]. Significantly, the endothelial BBB can be altered by ultrasound and contrast agents and may be a means of delivering drugs to the CNS due to altered permeability \[[@B27],[@B28]\]. Other vascular effects include micro vessel rupture, and cell death in the rat spinotrapezius muscle using Optison \[[@B29]\]. Further, petechiae, and capillary leakage was observed in the mouse abdomen following use of Optison \[[@B30]\]. Clearly, the coupling of integrin specific MAB to US contrast reagents may generate tissue specific contrast reagents but, there are nonspecific and collateral damage that results from the combined use of Optison and Ultrasound. Tumors are dependent upon the formation of neo-vessels for continued growth. Noninvasive, *in vivo*, imaging of vasculature is extremely important for identifying tumors. Most importantly, this permits a means of screening anti-tumor regimens in preclinical models and clinical applications. These imaging techniques also permit high-resolution, volumetric assessments of tumor vascularity. In a preclinical model of breast cancer is shown that correlates with other ultrasonographic measures of blood flow, which may provide greater sensitivity to the microvasculature in real time \[[@B31]\]. The endothelium of tumor neo-vessels express vascular cell endothelial growth factor receptor 2 (VEGFR2). UCA MicroMarker has been with conjugated to anti VEGFR2 have been used to follow angiogenesis in a preclinical murine model for breast tumors \[[@B32]\]. In a human xenograft melanoma model, immuohistochemical COX-2 staining of excised tumors correlated with the contrast-enhanced ultrasound image \[[@B33]\]. The imaging of angiogenesis is dependent upon the expression of tumor or endothelial markers such as VEGFR2. The expression of VEGFR2 may be variable, depending upon the growth stage/size and in humans, clonality. These imaging techniques also permit high-resolution, volumetric assessments of tumor vascularity. The utility of following VEGF receptor and signaling kinases as a marker of endothelial integrity is amply demonstrated in this paper. Inappropriate thrombus formation in the heart, brain or in a peripheral site is the hallmark of vascular disease. Imaging thrombus is an important application of Optison and US. Abciximab, which recognizes glycoprotein IIb/IIIa receptor was conjugated to Optison and the immuno bubbles enhance the image of arterial thrombus *in vivo*\[[@B34]\]. In contrast, US and USCA can be used in combination to break apart moderate sized clots \[[@B35]\]. In the rabbit ear, US and contrast agent were directed against the auricular vein. When fibrinogen was administered, the vein was occluded by an a thrombus \[[@B36]\]. These examples illustrate the usefulness in identifying thrombus as well as inducing thrombus to inhibit blood flow to a target lesion. The loss of vascular function that we observed in this study illustrates the collateral damage that can be induced. IVUS imaging of coronary and peripheral arteries is extremely useful technique to image plaque formation and vessel patency. Vulnerable plaque is an arterial lesion that has a propensity for rupture and thrombus formation. IVUS and contrast agent permits the visualization of vasa vasorum density and a combination of lipid core, cap thickness and calcification may help identify the plaques most likely to rupture \[[@B37]\]. Valvular stenosis can easily be visualized by ultrasound examination of the heart. The micro bubbles enhance the image of the ventricle making it easier to identify thrombus, calculate the volume of ejected blood and visualize wall motion. These functional studies are crucial for the clinical assessments of patients \[[@B38]\]. There are contradictory reports regarding the effect Optison on human cardiac function \[[@B39]\]. Perventricular contractions (PVCs) were noted in the human heart \[[@B40]\]. Troponin T was elevation was seen with Optison however, there were no negative histologic findings were seen \[[@B41]\]. In an other study, no changes were seen in PVCs, Troponin I, CK, CK-MB in the human heart \[[@B42]\]. In a preclinical model using the rat heart, PVCs, and microvascular leakage was noted with Optison \[[@B43],[@B44]\]. Importantly, micro lesions were seen histologically with inflammatory infiltrates 24 hours post exposure in the rat heart \[[@B44],[@B45]\]. In glass catfish model, US and USCA revealed focal damage in the tail of fish. Importantly, this was a real time assessment of the damage, which was significant \[[@B46]\]. Our results from this study are consistent with vascular damage that may contribute to the arrhythmias seen *in vivo*. Rat hearts were subjected to both US and Optison, and cardiac arrhythmias were induced. Cessation of US treatment reversed the effect. However, no histological effect was seen \[[@B47]\]. Rat hearts were treated with ultrasound and Optison, and the RNA was prepared for microarray analysis. The only gene up-regulated was carbonic anhydrase, so there was not dominant gene induction \[[@B48]\]. Use of ultrasound contrast agents, newly-developed microbubble-based products which are administered intravenously to enhance the ultrasound image quality, present new challenges with regard to clinical safety because of the locally destructive forces of inertial cavitation caused by the interaction of ultrasound with the micro bubbles. These destructive forces can damage the endothelium and smooth muscle of the vascular wall. The target patient population that may be exposed to microbubble/ultrasound is large and continues to grow as new applications and new products in this class are developed. For example, increased permeability due to contrast agent-induced vascular damage can capitalized upon therapeutically to deliver genes and other large molecules across endothelium. However, an adverse event that may occur from microbubble-induced vascular lesions may be the initiation or acceleration of atherosclerotic progression. Since this modality is being considered for delivery of drugs and genes, an even larger patient population (who originally had no cardiovascular disease) will be exposed to long-term risks. Therefore, it is critical to identify the ultrasound and microbubble exposure conditions which cause damage to the vascular endothelium and determine whether microbubble-induced vascular damage increases the risk of atherosclerosis in selected populations. There are several limitations in the present study: First, it was performed *ex vivo* under static conditions with no blood flow. Second, only one concentration of Optison was employed. In earlier studies (Miller, Dou, and Song 601--07; \[[@B6],[@B12],[@B39],[@B49]\], the microbubble concentration ranged from 0.01% to 2% and maximal RBC hemolysis was seen at 1%. In our experiment, we used 1% Optison, so we are using concentrations that are consistent with previous work. In clinical use, the recommended doses range from 0.5 to 5 ml of Optison infused in a 10 min period. For these studies, we used a 2 MHz US wave employing a four-cycle tone burst simulating a pulsed Doppler mode and having an MI of 1.9, the maximum setting available on a clinical imaging unit. It is not clear whether similar effects could occur at MI values less than 1.9. In conclusion, 2 MHz US with an MI of 1.9 and 1% Optison altered contraction and

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type of firm of course, but long-term owners of luxury brands come to mind.” The announcement seemed to give CEO Tad Smith an abundance of confidence about the company’s future: “When I said in the prior earnings call that we are going to have one or more bad quarters I think we are going to keep it to one,” he said Monday. “I feel good about things.”Doxofylline in rat brain in relation to locomotor activity. Doxofylline is a new xanthine derivative with significant bronchodilatatory activity. We have studied in HPLC the distribution of doxofylline in various areas of rat brain (cortex, cerebellum, limbic system) and its activity on the central nervous system by using a spontaneous motility test comparing it with aminophylline administered orally in equimolar doses (4.7 - 9.4 - 19 x 10(-5) mol/kg). Doxofylline is absorbed 3 or 4 times less than aminophylline at the same doses. Nevertheless, the quantity of doxofylline that goes to the brain is equivalent to that absorbed, whereas the quantity of aminophylline is about one-third. This is due to the greater liposolubility of doxofylline in comparison to aminophylline. In spite of the fact that doxofylline is easily distributed in the brain, spontaneous motility in animals is not modified, whereas aminophylline increases this activity significantly. The low affinity of doxofylline with adenosine receptors (A1 and A2) in comparison with aminophylline explains the lack of side effects on the central nervous system which has been amply documented for theophylline and for other methylxanthine derivatives.Ask HN: What podcasts do you listen to about the latest scientific discoveries? - AHappyCamper ====== nkb_ 60 seconds science [0] References: 0\. [https://www.scientificamerican.com/podcast/60-second- science...](https://www.scientificamerican.com/podcast/60-second-science/) Edit: 60 seconds science has a nugget of science news a day. It is a quick way to highlight a topic and a breakthrough in the area. When I like the info I dig further into the topic. President Jacob Zuma has signed proclamations authorising the Special Investigating Unit (SIU) to investigate certain matters in respect of the affairs of two district municipalities and a provincial department. Thick grey smog pressed against Zhao Jian's windshield, blotting visibility to two metres as he drove through China's most polluted city. Save & Share Related News "I don't remember ever seeing air pollution so bad," said Zhao of the weeks of recent haze that saw hazardous air hanging across swathes of the country. But like others in Xingtai, a 3,000-year-old city that in February was officially declared to have the country's worst air pollution, Zhao has no hope for improvement. "There's nothing you can do," he said. China's Communist leaders, currently gathered in Beijing for the annual meeting of the country's rubber-stamp parliament, the National People's Congress, have promised action on pollution in response to growing public outrage. The capital itself has seen particulate levels almost 40 times World Health Organisation (WHO) limits, and the pollution is inflicting a heavy toll on both human health and economic activity. "The state of the ecological environment affects the level of the people's well-being and also posterity and the future of our nation," Premier Wen Jiabao said in an address to the congress. "We should resolve to solve the problems of serious air, water, and soil pollution that affect the people's vital interests." Air pollution caused at least 8,572 premature deaths in four of China's biggest cities last year, and 6.8 billion yuan ($1.1 billion) in economic losses, according to a study by Peking University and Greenpeace published in December. But analysts say that without a serious threat of social unrest, China's rulers are unlikely to abandon their focus on economic growth or take radical action on polluting industries in the face of powerful vested interests. Metres away from the towering smokestacks of Xingtai's sprawling steel plants -- many of them state-owned -- shopkeepers have no difficulty pointing out the source of the pollution. Nearly half of China's emissions of PM2.5 -- tiny particles that penetrate deep into the lungs -- come from coal burning, with the rest mostly from vehicle emissions and construction. Three provinces surrounding Xingtai, 350 kilometres (220 miles) south of Beijing, burned through almost 400 million tonnes of coal last year --nearly half the total consumption of the United States. Experts agree that any meaningful action on pollution will mean cutting dependence on coal, but say Beijing's current stance will see its use rise. "We see nothing in the current policy that could meaningfully slow down the pace of coal consumption," Deutsche Bank said in a report this month. Locals said measures to reduce air pollution are unevenly enforced because of bribery. "You give the government some money and they won't do anything," Zhang said, miming the action of slipping cash into an official's pocket. While China's leaders have repeatedly stated the importance of cleaning up the pollution, responsibility for reducing emissions falls to environmental protection bureaus at the local level. Xingtai's bureau takes up a few floors of dusty, undecorated offices above a cake shop. "We're meant to implement emissions reductions policies, but we're too weak," said an official surnamed Wang, sitting opposite an ageing computer showing the day's PM2.5 reading at 179 -- seven times the WHO limit. "It's a moderate day for us," he added. China began to publish PM2.5 data for 74 cities in January, after public calls for greater transparency on the issue. State media have been unusually outspoken over the smog outbreaks. "This choking, dirty and poisonous air forces Chinese people to rethink the widespread, messy development model," said the China Youth Daily. Protests triggered by environmental issues in China have grown by almost 30 percent a year since 1996, according to the China Daily, but air pollution has not yet provoked the same level of street action as for water and land. "People are concerned about air because now they can see it," said Yang Fuqiang, a senior advisor in Beijing for the US-based Natural Resources Defense Council. "The pressure from the public is much stronger than before, but still not big enough." In his congress speech, Premier Wen restated the Communist Party's long-standing position that "development is still the key to solving all our problems". Standing on a river bank in the shadow of a huge coal-fired power station, a Xingtai estate agent who gave his surname as Wang summed up the situation. "Nearly everyone has a house and enough to eat now, so people will care about the environment more," he said.Explore Special Week Long Education Events at Travis County Parks with the Leave No Trace Traveling Trainers to Help Preserve and Protect Natural Resources for Generations to Come Leave No Trace Selected Travis County Parks as an Endangered ‘Hot Spot’ and are Hosting Events to Help Raise Awareness about Natural Areas Around the Country Facing the Threat of Irreversible Environmental Damage March 23, 2015 (Travis County, TX) The Leave No Trace Center for Outdoor Ethics and its Leave No Trace Traveling Trainers team are partnering with Travis County Parks to host community events and educational activities March 23-30th, 2015. The scenic and popular Travis County Parks have experienced visitor-created impacts in recent years including excessive trash, damage to vegetation, trees and trail erosion. Leave No Trace Traveling Trainers will focus on Hamilton Pool and Reimers’ Ranch, which are managed as sister parks due to their proximity to each other. The Hot Spot Program, a key component of the Leave No Trace in Every Park initiative, raises community awareness and brings solutions to popular natural areas facing heavy recreational use and consequently, the threat of harm to trails, parks and open space areas. The Leave No Trace Traveling Trainers travel throughout the country providing public education about how to reduce impacts in the outdoors. “The cumulative impact of so many people enjoying a great county park system such as Travis County Parks can negatively affect that place,” according to Courtney Bierschbach, Leave No Trace Traveling Trainer. “In most cases, the land impact isn’t due to a malicious intent to harm nature and wildlife. Instead, it’s simply lack of Leave No Trace education and practices.” “We are excited to work with the Leave No Trace Traveling Trainers to help educate our community and raise awareness for the future enjoyment and preservation of our beautiful landscape,” said Dan Perry Parks District Manager at Travis County Parks. During the week, Leave No Trace Traveling Trainers will provide private training sessions with County Park Staff and specific non-profit groups. On the weekend there will be a service project performed by the Texas State University Botany Club at Hamilton Pool. The following is a list of events happening in the Austin Area and in Travis County Parks with the Leave No Trace Traveling Trainers that are free and open to the public: Join the Leave No Trace Traveling Trainers at REI for this fun, informative and interactive community building presentation. This session

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will be compiled into the assembly, and if you're using a shared bin folder, you shouldn't need to do anything more. If they won't be shared, you'll have to attach to the AssemblyResolve and TypeResolve events in the global application (more on this here). We eventually scrapped this idea because of security concerns, and ended up going with MEF data contracts but if all of your other assemblies are first party, then this should be quick and easy. Hope this helps. <%= back_link_to admin_budget_groups_path(@budget) %> <h2><%= @budget.name %></h2> <h3><%= t("admin.budget_groups.form.#{action}") %></h3> 5. Seems like every time we have worn non traditional uniforms in the past we have lost. So based on that I would say no. Although if they came out in black helmets, jerseys and pants, that would be really cool.Q: didReceiveMemoryWarning from UITableView with Images created with url data followed by app termination due to memory pressure I am setting up a UITableview, and on the side of each cell is an image that is 80x80. The TableView works perfectly when the number of cells is less than 8, but any more than this and sometimes the scroll performance can have a minor delay. With a lot more cells (around 50), the scroll performance is fine as long as you dont make a big swipe down quickly. Also, when there are a lot of cells, if you stay on this view for too long and scroll up and down, the app will receive a memory warning, and then will eventually crash. Any tips for helping to save memory? Some of these images are pretty large (5000 x 1000), or how to clear some memory when didReceiveMemoryWarning is called? I'm using ARC if that is relevant. Here is the code I use to set up the cells: - (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath { CustomTableViewCell *cell = [tableView dequeueReusableCellWithIdentifier:@"ArticleCell"]; if(cell == nil){ cell = [[CustomTableViewCell alloc] initWithStyle:UITableViewCellStyleSubtitle reuseIdentifier:@"ArticleCell"]; } cell.titleLabel.text = nil; cell.imageRight.image = nil; Article *article = [self.articles objectAtIndex:indexPath.row]; [cell.titleLabel setText:article.title]; if(!article.pictureData){ dispatch_async(dispatch_get_global_queue(DISPATCH_QUEUE_PRIORITY_DEFAULT,0), ^{ NSData* data = [NSData dataWithContentsOfURL:[NSURL URLWithString:article.image]]; dispatch_sync(dispatch_get_main_queue(), ^{ article.pictureData = data; UIImage *img = [[UIImage alloc] initWithData:data]; CGSize imgSize = CGSizeMake(80, 80); img = [img resizeImage:img newSize:imgSize]; [cell.imageRight setImage:img]; [self.tableView beginUpdates]; [self.tableView reloadRowsAtIndexPaths:[NSArray arrayWithObjects:indexPath, nil] withRowAnimation:UITableViewRowAnimationNone]; [self.tableView endUpdates]; }); }); } else [cell.imageRight setImage:[UIImage imageWithData:article.pictureData]]; return cell; } The point is though that this tableView is loading all of the cells perfectly, and it can make it all the way through even 50+ rows. I just need to clear some memory, I'm just unsure how. A: Your cells are set up differently depending on whether the pictureData is available: If pictureData is not yet available, it will be downloaded & its full resolution data set on the article object; afterwards a smaller thumbnail image is generated and set on cell.imageRight. However, if the picture has already been downloaded, a full resolution image is created from pictureData and set on the cell's imageRight without resizing it first.. } else [cell.imageRight setImage:[UIImage imageWithData:article.pictureData]]; This means that as soon as all pictures have been loaded, each time the tableView dequeues a reusable cell it will also set the full res image on cell.imageRight. I suppose this explains the memory issues you are encountering. My advice would be to add a UIImage *thumbnail property to the articles object, cache the resized image there after it has been generated from the downloaded data and always use this -thumbnail for the cell's imageRight. Additionally, this will reduce the nontrivial system load (both on memory & cpu) caused by re-generating and resizing the images every time the tableView updates a cell. Another thing: there's actually no need to bother the main thread with the image resize operation, I suspect that's where the hitching comes from when scrolling. It should help to leave that on the global queue and dispatch_async only the table update to the main queue afterwards. U.S. church attendance is dropping, but Hope Church in Memphis, Tennessee, is packing the pews — or, in Hope’s case, modern theater seats with individual cup holders. The Evangelical Presbyterian Church affiliate, one of the fastest-growing in the nation, holds four services each weekend to accommodate the nearly 7,000 parishioners who come for the multiethnic community, the coffee kiosks, the mix of contemporary and traditional music, the outreach to non-churchgoers, and the biblically based message. Hope’s conservative stance on human sexuality — faithfulness in marriage, chastity in singleness, and marriage between one man and one woman — has done little, if anything, to rein in the church’s galloping growth. “I think what people appreciate, honestly, is do you believe what you say you believe?” said Hope senior pastor Rufus Smith. “If you’re going to be an [LGBTQ] affirming church, be that, and if you’re not, be that, so people will appreciate whatever your position of conscience is. And I think that is what has helped [evangelical] churches not experience a decline because of that particular issue.” Four years after the Supreme Court legalized same-sex marriage, conservative churches, led by the evangelicals and nondenominationals, still draw enthusiastic crowds each weekend to their megachurches, even as liberal mainline Protestant denominations wilt. “For evangelicals, being conservative is what has held them to that same level as a share of the population,” said Ryan P. Burge, an assistant professor of political science at Eastern Illinois University who tracks the data. Yet the future is uncertain as attendance plateaus. Evangelicals made up 22.5% of the U.S. population in 2018, and that share is expected to inch up to only 22.6% by 2030, according to Mr. Burge’s numbers, which are based on the General Social Survey, a trove of sociological data. A 2016 study led by Wilfrid Laurier University professor David Millard Haskell found that the “recipe for church growth” was conservative theology coupled with worship music featuring drums and guitars, but he said he thinks the growth has hit a wall since then. He also said cultural upheaval of gender issues and the battles it entails — such as same-sex wedding cakes, public accommodations and transgender athletes — is taking a toll. “What’s going on in the culture with the greater acceptance of gay marriage will make it harder for churches promoting traditional views,” Mr. Haskell said. But he added: “If a church stuck with their traditional views and were able to articulate it in a way that met the hearts and minds, the best research shows that keeping to those traditional values will cause your church to grow.” Religious conservative leaders at the national level see the fight over gender issues as make-or-break. “The current cultural attack is indeed about our right to live according to our faith and even about what it means to be a man or a woman,” said Mario Diaz, general counsel of Concerned Women for America. “That is why we are engaged there most prominently. When males are entering women’s private spaces and demanding to compete against them in sports, we must speak up.” ‘Culture war is dead’ Blaming same-sex marriage for the decline of Christian churchgoers in America would be too simplistic, religious scholars say, given that the slide can be traced to the turn of the century — the 19th century — and picked up steam during the sexual revolution of the 1960s. Mainline denominations that flowed with societal changes, such as the Episcopal Church, the Presbyterian Church (USA), the Evangelical Lutheran Church in America, and the United Church of Christ “have all seen dramatic declines in their membership and attendance as they liberalize their teachings on human sexuality,” said Keith Boyette, president of the Wesleyan Covenant Association. He said the same is true with the United Methodist Church, a mainline denomination grappling with a schism over same-sex marriage that is expected to play out

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gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Behavior:EC2/NetworkPortUnusual: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId sourceipaddress: details.finding.action.networkConnectionAction.localIpDetails.ipAddressV4 destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Behavior:EC2/TrafficVolumeUnusual: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId sourceipaddress: details.finding.action.networkConnectionAction.localIpDetails.ipAddressV4 destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Trojan:EC2/BlackholeTraffic: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.resource.instanceDetails.networkInterfaces tags: details.resource.instanceDetails.tags state: details.resource.instanceDetails.instanceState az: details.resource.instanceDetails.availabilityZone imageid: details.resource.instanceDetails.imageId imagedesc: details.resource.instanceDetails.imageDescription detectorid: details.finding.detectorId destinationipaddress: details.finding.action.networkConnectionAction.remoteIpDetails.ipAddressV4 sourceport: details.finding.action.networkConnectionAction.localPortDetails.port destinationport: details.finding.action.networkConnectionAction.remotePortDetails.port proto: details.finding.action.networkConnectionAction.protocol evidence: details.finding.evidence miscinfo: details.finding.additionalInfo platform: details.resource.instanceDetails.platform gdeventcreatedts: details.createdAt gdeventupdatedts: details.updatedAt gdeventfirstseents: details.finding.eventFirstSeen gdeventlastseents: details.finding.eventLastSeen networkinterfaceid: details.resource.instanceDetails.networkInterfaces.networkInterfaceId privatednsname: details.resource.instanceDetails.networkInterfaces.privateDnsName privateipaddress: details.resource.instanceDetails.networkInterfaces.privateIpAddress subnetid: details.resource.instanceDetails.networkInterfaces.subnetId vpcid: details.resource.instanceDetails.networkInterfaces.vpcId publicdnsname: details.resource.instanceDetails.networkInterfaces.publicDnsName publicip: details.resource.instanceDetails.networkInterfaces.publicIp direction: details.finding.action.networkConnectionAction.connectionDirection Trojan:EC2/DropPoint: findingid: details.id arn: details.arn awsaccountid: details.accountId awsregion: details.region resourcetype: details.resource.resourceType instanceid: details.resource.instanceDetails.instanceId instancetype: details.resource.instanceDetails.instanceType launchtime: details.resource.instanceDetails.launchTime iamprofilearn: details.resource.instanceDetails.iamInstanceProfile.arn iamprofileid: details.resource.instanceDetails.iamInstanceProfile.id net: details.

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be delayed. App. at 24. When it was disclosed in response to a March 3, 1982, oral inquiry that it would take DOJ several months to reach a decision, PLEI filed, on April 30, 1982, an FOIA complaint in the District Court. 3 On July 19, 1982, DOJ filed a motion for summary judgment. Accompanying the motion was the declaration of the Chief of the Freedom of Information Act and Privacy Act Unit within OLP. The declaration (1) released all but three and one-half lines of one of the documents, (2) described the remaining documents, and (3) claimed section 552(b)(2) and (b)(5) exemptions for the undisclosed material. App. at 31-40. On July 29, 1982, PLEI moved for leave to amend its complaint to include documents sought in a separate, later FOIA request, and on August 16, 1982, PLEI filed a motion for summary judgment. 4 On August 17 and 18, 1982, a hearing was held in San Diego in the criminal case United States v. Sasway, Crim. No. 82-0504 (S.D.Cal.1982). See PLEI, supra, 556 F.Supp. at 447. In that hearing, DOJ, in order to refute a defense claim of selective prosecution, publicly disclosed its guidelines for prosecuting Selective Service non-registrants. Id. Those guidelines and the cover letter transmitting the guidelines to United States Attorneys were two of the four documents sought by PLEI. On or about September 3, 1982, after the guidelines became public in Sasway, they and the cover letter were released to PLEI. Id. 5 DOJ continued to defend its position with regard to the withholding of the two remaining documents. On September 21, 1982, the District Court issued an order refusing leave to PLEI to amend its complaint and granting summary judgment for DOJ with regard to the two undisclosed documents, sustaining the claim of exemption under 5 U.S.C. Sec. 552(b)(5). App. at 59-60. 6 Subsequently, PLEI moved for an award of attorney's fees and litigation expenses, pursuant to 5 U.S.C. Sec. 552(a)(4)(E). The District Court denied PLEI's motion, holding that PLEI had not substantially prevailed in the FOIA action, as required under section 552(a)(4)(E), because no causal nexus had been shown between PLEI's action and the release of the two documents PLEI received. Alternatively, the District Court held that even if PLEI had substantially prevailed and was eligible for attorney's fees, an analysis of the factors enumerated in Cox v. United States Department of Justice, 601 F.2d 1, 7 (D.C.Cir.1979), for entitlement to such fees, showed that PLEI was not so entitled. II 7 An award of attorney's fees and litigation costs incurred in pressing an FOIA claim may be made only if the complainant has substantially prevailed. 5 U.S.C. Sec. 552(a)(4)(E). While it is clear that a court order compelling disclosure is not a prerequisite for an award,1 it is also clear that more than post hoc, ergo propter hoc must be shown.2 An FOIA litigant seeking attorney's fees must show that "prosecution of the action could reasonably be regarded as necessary to obtain the information ... and that a causal nexus exists between that action and the agency's surrender of the information ...." Cox v. United States Department of Justice, supra, 601 F.2d at 6 (citations omitted); see also Sweatt v. United States Navy, supra, 683 F.2d at 423-24; Church of Scientology v. Harris, supra, 653 F.2d at 588. 8 To be sure, the Justice Department's release of the two documents at issue in the attorney's fees motion did occur after the filing of an FOIA complaint. However, the initial release of the documents occurred in an unrelated criminal case. Only then did DOJ release the documents to PLEI, specifically representing to the District Court that "[i]n view of the public disclosure of the guidelines, [DOJ] will discontinue its efforts to withhold these materials." Filing of September 3, 1982, App. at 44. The Justice Department released only those documents which had already been publicly disclosed; it did not release the other documents that were the subject of PLEI's FOIA action. The District Court thus concluded that PLEI failed to show a causal nexus between its FOIA action and DOJ's release of the documents. 9 Our review of the District Court's conclusion that PLEI did not substantially prevail in the litigation, so as to be eligible for attorney's fees, is narrow in scope. The findings of fact underlying a conclusion as to whether an FOIA litigant has substantially prevailed are reviewed under a clearly-erroneous standard. See Sweatt v. United States Navy, supra, 683 F.2d at 425; Crooker v. United States Department of the Treasury, supra, 663 F.2d at 142. In this case, there is no dispute as to the findings of fact. Thus, the District Court's findings of fact are manifestly not clearly erroneous. 10 Nor is there any indication that in reaching its conclusion the District Court applied an improper legal standard to those findings of fact.3 PLEI would have us find legal error by interpreting the causal nexus requirement in significantly weakened form. PLEI argues that an FOIA plaintiff need not show that its suit was a direct cause of the release of the documents sought. Appellant's Brief at 28. However, the cases cited for this proposition fail to support it. In each case, the release of the documents was directly attributable to the plaintiff's FOIA action.4 Alternatively, PLEI invites us to infer causality from the timing of the release of the documents. Appellant's Brief at 32-33. Such an inference, however, would be contrary to the law of this Circuit.5 11 There is no indication in the record or in the District Court's findings of fact that would indicate that the PLEI action influenced the DOJ decision to release the documents in Sasway. Nor is there any indication that DOJ simply abandoned its defenses to PLEI's claim. The District Court appears to have understood, and to have correctly applied, the causal nexus requirement. Accordingly, we must accept the District Court's finding that PLEI was not eligible for an award of attorney's fees. 12 Only movants who have prevailed substantially, and are therefore eligible, may be found entitled to an award of attorney's fees and litigation expenses under section 552(a)(4)(E). See Fund for Constitutional Government v. National Archives & Records Service, supra, 656 F.2d at 870; Church of Scientology v. Harris, supra, 653 F.2d at 587; Nationwide Building Maintenance, Inc. v. Sampson, supra, 559 F.2d at 709. Since PLEI is not eligible for an award of attorney's fees and litigation expenses, we have no occasion to comment on the factors that would bear on PLEI's entitlement.6 13 For the foregoing reasons, the judgment of the District Court is 14 Affirmed. * Sitting by designation pursuant to 28 U.S.C. Sec. 294(d) 1 Sweatt v. United States Navy, 683 F.2d 420, 423 (D.C.Cir.1982); Fund for Constitutional Government v. National Archives & Records Service, 656 F.2d 856, 871 (D.C.Cir.1981); Church of Scientology v. Harris, 653 F.2d 584, 587 (D.C.Cir.1981); Crooker v. United States Department of the Treasury, 663 F.2d 140, 141 (D.C.Cir.1980); Cox v. United States Department of Justice, 601 F.2d 1, 6 (D.C.Cir.1979); Nationwide Building Maintenance, Inc. v. Sampson, 559 F.2d 704, 708 (D.C.Cir.1977); Cuneo v. Rumsfeld, 553 F.2d 1360, 1364 (D.C.Cir.1977) 2 Sweatt v. United States Navy, supra, 683 F.2d at 423; Church of Scientology v. Harris, supra, 653 F.2d at 587-88; Cox v. United States Department of Justice, supra, 601 F.2d at 6 3 See generally United States v. Singer Manufacturing Co., 374 U.S. 174, 194 n. 9, 83 S.Ct. 1773, 1784 n. 9, 10 L.Ed.2d 823 (1963); Federal Trade Commission v. Texaco, Inc., 555 F.2d 862, 876 n. 29 (D.C.Cir.), cert. denied sub nom. Standard Oil Co. v. Federal Trade Commission, 431 U.S. 974, 97 S.Ct. 2939,

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below the armpit. Spread or overlap the line evenly to achieve the correct back length. 3. Redraw lines if needed by blending the pattern lines at the overlap or spread. For preliminary front adjustments, you need to lengthen or shorten the front bodice the same amount as you did the back bodice. ## BUST ADJUSTMENTS All standard bodice patterns are made for a B-cup bra size. If you are smaller or larger than a B cup, and/or your bust sits higher or lower than average, then you'll want to adjust your pattern before you start to get a better fit. 1. With the elastic still around your waist, look in a mirror and measure vertically from your shoulder, over the fullest part of your bust, and down to your waist. The bodice front needs to be this long to fit properly. Also note the measurement along that line, where the apex of your bust (or bust point, basically your nipple) sits. You'll need this to mark an accurate bust point on your pattern. 2. Measure from side seam to side seam, across the fullest part of your bust. Add 1" (2.5cm) for wearing ease. Divide in half (because the pattern is half of the front). Also note the distance from the side seam to the bust point. 3. On the front bodice pattern, locate the pattern's bust point by drawing straight lines through the center of each dart. Where they intersect is the pattern's bust point. Mark the bust point on the pattern and mark the dotted lines as pictured. Cut along each of these lines, leaving only a small hinge at the armhole and, for the large bust adjustment, also at the bust point to pivot the pieces. For a small bust adjustment cut through the bust point. 4. Working on a flat surface, spread or overlap the pattern pieces as shown until the length and width measurements you took earlier are achieved. Keep the waistline of the bodice even and the center-front line even. A general rule will be to increase/decrease length and width about ½" (13mm) per change in cup size. For instance, a D cup will add about 1" (2.5cm) in length and width. Tape the altered pattern in place. 5. Mark the correct bust point on the pattern as you measured on yourself earlier, both the height (as measured from your shoulder) and the width (as measured from the side seam). Mark new waist and bust dart points as follows: The point of the waist dart will be 1" (2.5cm) directly below your new bust point. The side dart point will be 1" (2.5cm) away from your bust point, in the direction of the dart (to the side and slightly down). Connect these new points to the end of the legs of the original darts, which have now spread (for larger cups) or overlapped (for smaller cups). Redraw pattern lines smoothing out any bumps or jags caused by the alteration. 6. If the bust point is higher than its original position, redraw the darts to point toward the higher point. In cases where the corrected bust point is lower than the side dart end points, the side dart end points will also have to be lowered. Measure the distance that the bust point was lowered. Lower the end points of the dart legs the same distance, taking care to lower them vertically. In other words, move the entire side dart downward, not just the tip, on the spread-out or overlapped pattern. This keeps the width of the front bodice consistent. Draw in the new dart legs, lowering the tip of the waist dart the same amount the bust dart was lowered on the spread or overlapped pattern. 7. To complete the pattern, redraw the side seam by connecting the new dart legs with the armhole and the waistline for the spread or overlapped pattern. ## NECK ADJUSTMENTS If the neckline is too tight or too loose, adjust the pattern accordingly. 1. Measure around your neck where you'd like the finished neckline to sit. Divide the measurement in half as you are working with half the pattern. 2. Mark the stitching lines for the neck and shoulder on both the front and back bodice, ⅝" (1.5cm) in from the cutting edge. Line up the shoulder stitching lines and tape in place. Don't worry about the shoulder dart. Measure the stitching line for the neck by holding a soft, flexible tape measure on its side (that is, standing up on its thin edge), not flat, around the neck stitching line. Hold it so the increments are against the pattern for the most accurate measure. 3. For every 1" (2.5cm) difference between the stitching line and the target measure, move the pattern's neckline ¼" (6mm) at the center front and at the shoulder line, either in, toward the neck to make it smaller, or out, away from the neck to make it bigger. For example, if you want to increase the neck 1" (2.5cm), you'll move the center-front point down ¼" (6mm) and the shoulder line out ¼" (6mm). Keep the center back the same. Redraw the neck stitching line, and double-check the pattern measure. Add the ⅝" (1.5cm) seam allowance to the stitching line. Adjust again if needed. ## SHOULDER ADJUSTMENTS ### SHOULDER SLOPE CORRECTION This method will correct for wide or narrow shoulders, as well as square or sloping shoulders. 1. Have a friend measure across your back, from shoulder point to shoulder point, where sleeve seams would sit. This is your shoulder width. Divide this by 2, since the pattern is for half of the back. Then, with the elastic around your waist, have a friend measure from your waist at center back, to your shoulder point, where a sleeve seam would sit. This is the shoulder slope. 2. Compare your shoulder width (that you've divided by 2) to the bodice back, omitting the seam allowances. If you're within ¼" (6mm), you'll be fine. If not, you'll want to correct for shoulder width. Do this before correcting for shoulder slope. Draw a horizontal guideline, parallel to the waist, through the shoulder point. Starting at center back, measure along this line to your target shoulder width. Make a mark on the line. Next, draw a vertical line through your mark, keeping it perpendicular to the waistline to mark the wider or narrower shoulder. 3. Starting at the waist at center back, mark where your shoulder-slope measure crosses the vertical line. This is your new shoulder point. Note how far above or below the original shoulder point this is, as you will need to adjust the armhole this same amount. Draw your new shoulder line from this point to the neck. 4. Find the midpoint of your new shoulder line. This will be the center of your shoulder dart. At the midpoint, draw a line perpendicular to your shoulder line that is the same length as the original dart. This is your dart center, and the end is your dart point. Measure the width of the original dart. Mark the dart width on the shoulder line with the perpendicular line in the center. Draw in your dart legs, connecting these marks to the end of the perpendicular line. 5. Correct the armhole as needed: If your shoulder width was adjusted, but not the shoulder slope, redraw your armhole, starting at the shoulder, and blend back into the existing armhole about midway down the curve for the wider or narrower shoulder. If your shoulder slope was also changed, draw a vertical guideline at the outer point of the armhole/side seam, perpendicular to the waist. Mark a new point along this guideline up or down—the same amount that you raised or lowered the shoulder point. This keeps the armhole the same size. To redraw this line, try to mimic the bottom of the curve through the midpoint of the curve. Then blend to your new shoulder point for a wider or narrower shoulder. 6. Apply the same changes to the front bodice: Draw a horizontal guideline through the front bodice shoulder point. Move the shoulder point in or out the same amount that you moved the back shoulder. Draw a vertical line through this new point. Now raise or lower the shoulder point the same amount that you raised or lowered it in the back, to correct for shoulder slope. Connect this mark to the original neckline. Redraw the armhole as in step 5. 7. When you change the armhole on the bodice, you then must change the armhole on the sleeve so it still fits into the bodice. For shoulder width adjustments, you may or may not need to adjust the armhole, depending on the changes. Measure the original armhole stitching lines on the back bodice. Now measure your new armhole on your back bodice, along the stitching lines. The difference between the two measurements is the amount that you will raise or lower the sleeve cap. If your new armhole is bigger than the original armhole, you will raise the sleeve cap by that same amount. If your new armhole is smaller than the original armhole, you will lower the sleeve cap by that amount. ### ROUNDED SHOULDERS For figures with rounded shoulders, there are often gaping armholes in the back, and when viewed from the side, the shoulders are forward from the neck and the back is more prominent than the front.

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ndigung: Ein Geistergespräch zwischen Lyotard und Habermas_ (Frankfurt: Suhrkamp, 1988). 11 Albrecht Wellmer, "On the Dialectic of Modernism and Postmodernism," trans. D. Roberts, _Praxis International_ , 5.5 (1985): 337–62. 12 Axel Honneth, _Critique of Power: Reflective Stages in a Critical Social Theory_ , trans. K. Baynes (Cambridge, MA: MIT Press), 1993. 13 See J. Habermas, _The Philosophical Discourse of Modernity: Twelve Lectures_ , trans. F. G. Lawrence (Cambridge, MA: MIT Press, 1998), here pp. 83–105. 14 See J.-F. Lyotard, _Des dispositifs pulsionnels_ (Paris: Bourgois, 1973), p. 118. [Translator's note: The chapter on "Adorno as the Devil" is available in English in Robert Hurley's translation in _Telos_ , 19 (1974): 128–37.] 15 Lyotard, _The Postmodern Explained to Children_ , p. 78. 16 The relationship between Adorno and Lyotard is analyzed in all its twists and turns by M. Cohen-Halimi, _Stridence spéculative: Adorno, Lyotard, Derrida_ (Paris: Payot, 2014), through oblique reference to Derrida. At the Cerisy-La-Salle conference – whose proceedings were later collected in the volume _Les Fins de l'homme: À partir du travail de Jacques Derrida_ (Paris: Galilée, 1981) – Lyotard asked Derrida to speak about his relationship with Adorno. The answer came only several years later, in 2001, when Derrida received the Adorno prize and gave a speech later published in _Fichus_ (Paris: Galilée, 2002) in which he accorded Adorno _le mérite indéniable_ of having reopened the question on the meaning of the phrase "after Auschwitz." 17 J.-F. Lyotard, _Discours, Figures_ , trans. A. Hudek and M. Lydon (with introduction by J. Mowitt; (Minneapolis: University of Minnesota Press, 2011 [1971]). 18 As Alain Badiou expresses it in "Custos, quid noctis?" [1983], in idem, _The Adventure of French Philosophy_ , 223–39, here p. 231. 19 See especially J.-F. Lyotard, _The Differend: Phrases in Dispute_ , trans. G. van den Abbeele (Minneapolis: University of Minnesota Press, 1988). 20 Lyotard, _The Postmodern Explained to Children_ , pp. 15–16. 21 Ibid., p. 16. 22 J.-F. Lyotard, _Heidegger and "the Jews,"_ trans. A. Michel and M. Roberts (with foreword by D. Carroll; Minneapolis: University of Minnesota Press, 1990), p. 84. 23 J.-F. Lyotard, _Enthusiasm_ , trans. G. van den Abbeele (Stanford, CA: Stanford University Press, 2009 [1986]), p. 58. # Part III French Theory # 7 Difference and History Perhaps no definition of French theory hits the mark better than Baudrillard's, according to which "it exists only when our eyes are closed."1 Like a fantasy imprinted in the mind but lacking any correspondence in reality, it is only recognizable by its effects – which radiated out from American campuses onto the global cultural stage over the span of a few years. As François Cusset observes in the most convincing reconstruction of the affair, it involved something different from and bigger than what other waves of cultural importation had brought from France to America. While surrealism, existentialism, and "Annales" historiography were transplanted in their native form before being Americanized, French theory was a product created from scratch by American intellectuals after a small squad of French philosophers arrived in the United States. Cogently defined as "an American interpretation of French readings of German philosophers,"2 it appears to be the result of a dual decontextualization – of German philosophical culture, as operated by the French, and of French philosophical culture, as operated by the Americans. The same liberty that Derrida, Deleuze, and Foucault took in reworking texts by Hegel, Nietzsche, and Heidegger was practiced by American interpreters on French authors. As had already happened the first time round, the effect of this second contamination was twofold. Although it is true that the French texts lost something of their original character by being first denationalized and then reterritorialized, once they came into contact with the new context they acquired a new-found energy, which projected them into the international circuit, in English translation. Certainly a French book arriving in Tokyo or Sydney through American mediation is no longer the same as it was. But, instead of diminishing its impact, this ended up boosting its force, as more meanings came to be layered on top of the original ones. Without retracing the ambivalent effects of French theory on American culture, which have been thoroughly examined by Cusset, I will stick to the relationship with German philosophy, transplanted in America by intellectuals who fled Nazi Germany. The general turnover in hegemony witnessed by the marginalization of Marcuse's thought was followed by a hybridization that blurred the European contrasts. What in Europe had taken on the features of a genuine _Kulturkampf_ in America became a composite of heterogeneous elements. American authors such as Nancy Fraser, Seyla Benhabib, and Martin Jay introduced Frankfurt School theories into the American context, while others, such as Silvère Lotringer, Judith Butler, and Gayatri Spivak circulated theories from France in a horizon marked by the interweaving of different lexicons. These grafts between French thinkers and German philosophy, already attempted in Europe by Wellmer and Honneth, intensified until among them they fused forms of thought of different origins, in a typically American, transnational model. Nevertheless, some differences did remain, associated with the different meanings that the term "theory" acquired in the two contexts. With the Frankfurt thinkers it retained a clear philosophical inflection, but in France "theory" tended to express a potential of meaning that, if not contrary to philosophy, was certainly not entirely coincident with it. Incongruent with the traditional meaning of "doctrine" (according to the use deriving from the German term _Lehre_ ), the French version of _théorie_ stemmed partly from the development of the human sciences and partly from the Marxist critique of ideology, as developed chiefly by Althusser, through the notion of "theoretical practice." This meaning, inspired by an ideal of scientificity that is not specifically theoretical in tone, gained currency in the disciplines of linguistics (Saussure), anthropology (Lévi-Strauss), psychoanalysis (Lacan), and literary studies (Barthes), in line with the rationalist cast of history of science (Lecourt).3 Thus, while critical theory in Frankfurt focused on the "criticality" pole from a philosophical angle, in Paris the stress was placed on a notion of "theory" with an antitheoretical leaning. In an article entitled "Doing Theory," Silvère Lotringer, perhaps the most important mediator of French theory in America, argues that its peculiar trait lies precisely in its lack of theoretical assumptions in favor of a practice of writing that prefers to dictate its own rules. Unlike _Kritische Theorie_ , which was guided by precise doctrinal premises, French theory had as an essential characteristic that it was not "to be something" but "to become everything it is capable of."4 From this point of view, in principle, it eludes any stable definition, taking on the meaning given to it from one time to the next. This explains its attitude of embracing even markedly heterogeneous theoretical presuppositions and semantic vectors, such as those adopted by Derrida, Foucault, Deleuze, Baudrillard, and Lyotard, to name only the major players. For this reason, in an interview "On Theory" – as well as in the talk he gave at the 1966 conference at Johns Hopkins University that effectively inaugurated the American period of French theory – Roland Barthes asserted the structurally "intransitive" pursuit of theory. It has no other object than itself, in all possible versions, including that of its own negation, to the point that even the antitheoretical polemic tends to become a genre within the very theory it aims to refute.5 If the protocols of French theory have been held responsible for both identity and difference politics in American public discourse, inferring a particular political goal from the various deconstructive practices is difficult and somewhat arbitrary. What they aim to challenge on a metapolitical plane is the form of representation – understood as the subject's apparatus for controlling reality. The reason why the structure of signification comes under attack, in all its possible modes, is that it is inevitably partial, and therefore excludes all other possible meanings. Opposed to it is the complete commutability of utterances, which are conveyed in such a way as to neutralize each other. Thus, for example, Baudrillard's argument on the equivalence between use value and exchange value serves to criticize capitalism as well as to overcome Marxism – but also, at the same time, to affirm one and the other

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public final boolean isBigDecimalShape() { return getType() == ShapeType.BIG_DECIMAL; } /** * @return Returns true if the shape is a {@link BigIntegerShape} shape. */ public final boolean isBigIntegerShape() { return getType() == ShapeType.BIG_INTEGER; } /** * @return Returns true if the shape is a {@link BlobShape} shape. */ public final boolean isBlobShape() { return getType() == ShapeType.BLOB; } /** * @return Returns true if the shape is a {@link BooleanShape} shape. */ public final boolean isBooleanShape() { return getType() == ShapeType.BOOLEAN; } /** * @return Returns true if the shape is a {@link ByteShape} shape. */ public final boolean isByteShape() { return getType() == ShapeType.BYTE; } /** * @return Returns true if the shape is a {@link ShortShape} shape. */ public final boolean isShortShape() { return getType() == ShapeType.SHORT; } /** * @return Returns true if the shape is a {@link FloatShape} shape. */ public final boolean isFloatShape() { return getType() == ShapeType.FLOAT; } /** * @return Returns true if the shape is an {@link DocumentShape} shape. */ public final boolean isDocumentShape() { return getType() == ShapeType.DOCUMENT; } /** * @return Returns true if the shape is an {@link DoubleShape} shape. */ public final boolean isDoubleShape() { return getType() == ShapeType.DOUBLE; } /** * @return Returns true if the shape is a {@link ListShape} shape. */ public final boolean isListShape() { return getType() == ShapeType.LIST; } /** * @return Returns true if the shape is a {@link SetShape} shape. */ public final boolean isSetShape() { return getType() == ShapeType.SET; } /** * @return Returns true if the shape is a {@link IntegerShape} shape. */ public final boolean isIntegerShape() { return getType() == ShapeType.INTEGER; } /** * @return Returns true if the shape is a {@link LongShape} shape. */ public final boolean isLongShape() { return getType() == ShapeType.LONG; } /** * @return Returns true if the shape is a {@link MapShape} shape. */ public final boolean isMapShape() { return getType() == ShapeType.MAP; } /** * @return Returns true if the shape is a {@link MemberShape} shape. */ public final boolean isMemberShape() { return getType() == ShapeType.MEMBER; } /** * @return Returns true if the shape is an {@link OperationShape} shape. */ public final boolean isOperationShape() { return getType() == ShapeType.OPERATION; } /** * @return Returns true if the shape is a {@link ResourceShape} shape. */ public final boolean isResourceShape() { return getType() == ShapeType.RESOURCE; } /** * @return Returns true if the shape is a {@link ServiceShape} shape. */ public final boolean isServiceShape() { return getType() == ShapeType.SERVICE; } /** * @return Returns true if the shape is a {@link StringShape} shape. */ public final boolean isStringShape() { return getType() == ShapeType.STRING; } /** * @return Returns true if the shape is a {@link StructureShape} shape. */ public final boolean isStructureShape() { return getType() == ShapeType.STRUCTURE; } /** * @return Returns true if the shape is a {@link UnionShape} shape. */ public final boolean isUnionShape() { return getType() == ShapeType.UNION; } /** * @return Returns true if the shape is a {@link TimestampShape} shape. */ public final boolean isTimestampShape() { return getType() == ShapeType.TIMESTAMP; } /** * Gets all of the members contained in the shape. * * @return Returns the members contained in the shape (if any). */ public Collection<MemberShape> members() { return Collections.emptyList(); } @Override public ShapeId toShapeId() { return id; } @Override public final List<String> getTags() { return getTrait(TagsTrait.class).map(TagsTrait::getValues).orElseGet(Collections::emptyList); } @Override public final SourceLocation getSourceLocation() { return source; } @Override public int compareTo(Shape other) { return getId().compareTo(other.getId()); } @Override public final String toString() { return "(" + getType() + ": `" + getId() + "`)"; } @Override public int hashCode() { return getId().hashCode() + 3 * getType().hashCode(); } @Override public boolean equals(Object o) { if (o == this) { return true; } else if (!(o instanceof Shape)) { return false; } Shape other = (Shape) o; return getId().equals(other.getId()) && getType() == other.getType() && traits.equals(other.traits); } } --- abstract: 'Quantum algorithms are usually described as monolithic circuits, becoming large at modest input size. Near-term quantum architectures can only manage a small number of qubits. We develop an automated method to distribute quantum circuits over multiple agents, minimising quantum communication between them. We reduce the problem to hypergraph partitioning and then solve it with state-of-the-art optimisers. This makes our approach useful in practice, unlike previous methods. Our implementation is evaluated on five quantum circuits of practical relevance.' author: - 'Pablo Andr[é]{}s-Mart[í]{}nez' - Chris Heunen bibliography: - 'Bibliography.bib' title: Automated distribution of quantum circuits via hypergraph partitioning --- [^1] [^2] Introduction ============ Quantum computation [@feynman; @nielsenchuang; @lloyd:simulators] employs the laws of quantum mechanics to design systems capable of outperforming classical computers in certain problems [@Shor; @Grover; @harrowhassadimlloyd:linear]. Over the past couple of decades, this idea has rapidly developed from theoretical results into actual quantum technology [@obrienfurusawavuckovic:photonic; @devoretschoelkopf:superconducting; @horodecki:entanglement]. Although there are other approaches [@raussendorfbriegel:mbqc], the dominant way to present a quantum algorithm is as a quantum circuit [@deutsch:networks]: a description of how quantum devices, chosen from a fixed finite set, are applied to different parts of the input system; see Figure \[fig:circuit\] for an example. Each of the ‘wires’ that quantum devices act upon typically consist of a two level quantum system called a quantum bit or qubit. The qubit count grows with the input size, and for relevant problems such as the *unique shortest vector* problem (with applications in cryptography [@USV]) the circuit grows large: lattice dimension 3 already requires 842 qubits and 95,624 gates [^3]. Near-term quantum computing architectures are not capable of executing such large circuits. We are currently entering the era of Noisy Intermediate-Scale Quantum (NISQ) technology [@NISQ], being able to fabricate small quantum computing units (QPU for short) ranging from $10$ to almost $100$ qubits. Much effort is being dedicated to further increase the number of qubits that QPUs can manage, but as the number of qubits grows, the challenge of addressing each qubit individually and shielding them from unwanted interactions and decoherence rapidly becomes unmanageable [@vanmeterdevitt:survey]. To scale up beyond this point, researchers are proposing distributed quantum architectures