jeffreygwang/pythia_dedupe_mia_0-70000_70000-98500

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15, 1723, 13, 352, 3133, 16872, 310, 2057, 13603, 390, 417, 4516, 407, 634, 9882, 15, 34747, 16872, 407, 6890, 634, 9882, 4610, 13, 285, 840, 1611, 969, 15, 187, 187, 6872, 28049, 403, 4158, 281, 8171, 1485, 395, 40513, 30161, 342, 15862, 30161, 275, 40745, 7871, 15, 5815, 3386, 27973 ]	pm ct, the shape of his assassination, we determine computing machine vigil ceremonies and get back his life principle of violent aim action. Kinsfolk with sentiments across the persuasion compass square measure invited to unify and perceive frequent reach against corruption. We disinherit overpower water parting and usurp propaganda by take shape communities of hold and compassion.College wrestler suspended for homophobic tweets about Michael Sam A Kent State wrestler is in hot water after sending out some offensive tweets about Michael Sam. Kent State sophomore Sam Wheeler used anti-gay language while complaining that Sam, the first openly gay NFL draft prospect, was the only story on SportsCenter on Monday. The university suspended Wheeler indefinitely. Sam announced he is gay on Sunday night. He won SEC Defensive Player of the Year after recording 11.5 sacks for Missouri last season. “We are aware of the insensitive tweets by one of our student athletes,” director of athletics Joel Nielsen said in a statement released by Kent State. “On behalf of Kent State University, we consider these comments to be ignorant and not indicative of the beliefs held by our university community as a whole. This is an educational opportunity for all of our student-athletes.” “As an alum of Kent State University and as Sam’s head coach, I was surprised and offended by what I read on Twitter,” wrestling coach Jim Andrassy said in a statement. “I have spoken to Sam personally, and while he is remorseful, he will be suspended indefinitely while we determine the best course of action moving forward.”Hermansky-Pudlak syndrome Common Name(s) Hermansky-Pudlak syndrome is a multisystem, genetic condition characterized blood platelet dysfunction with prolonged bleeding, visual impairment, and abnormally light coloring of the skin, hair, and eyes (oculocutaneous albinism). Long-term sun exposure greatly increases the risk of skin damage and skin cancers. Some individuals have colitis, kidney failure, and pulmonary fibrosis. Symptoms of pulmonary fibrosis usually appear during the early thirties and rapidly worsen. This condition is inherited in an autosomal recessive fashion. There are eight different types of Hermansky-Pudlak syndrome, which can be distinguished by their signs and symptoms and underlying genetic cause. Types 1 and 4 are the most severe forms. Types 1, 2, and 4 are the only types associated with pulmonary fibrosis. Individuals with type 3, 5, or 6 have the mildest symptoms of all the types. Little is known about the signs, symptoms, and severity of types 7 and 8. To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders. How do you compare to others with this condition? Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives. Advocacy and Support Organizations Condition Specific Organizations Following organizations serve the condition "Hermansky-Pudlak syndrome" for support, advocacy or research. To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders. General Support Organizations Recommended Apps Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives. Finding the right clinical trial for Hermansky-Pudlak syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity. Scientific Literature Articles from the PubMed Database Research articles describe the outcome of a single study. They are the published results of original research. The terms "Hermansky-Pudlak syndrome" returned 94 free, full-text research articles on human participants. First 3 results: We herein report a case of Hermansky-Pudlak syndrome (HPS) with nonspecific interstitial pneumonia (NSIP). A 58-year-old Japanese woman presented with oculocutaneous albinism and dyspnea on exertion. A high resolution computed tomography scan showed areas of reticular and ground glass ... Reviews from the PubMed Database Review articles summarize what is currently known about a disease. They discuss research previously published by others. The terms "Hermansky-Pudlak syndrome" returned 2 free, full-text review articles on human participants. First 3 results: Hermansky-Pudlak syndrome (HPS) is a rare genetic disorder, the most common complication of which influencing the prognosis is pulmonary fibrosis. In the present report, we describe an autopsy case of a Japanese woman with HPS. The patient was diagnosed at 50 years of age based on ... According to ClinicalTrials.gov there are currently 0 additional "open" studies for "Hermansky-Pudlak syndrome" (open studies are recruiting volunteers) and 7 "Hermansky-Pudlak syndrome" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance: Relief is when you and the right researcher find each other Finding the right clinical trial for Hermansky-Pudlak syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.Jessica Shipmanis an experienced web developer, software engineer, and WordPress blogger. With the goal of making technology less scary for bloggers and small businesses, Jessica offers a variety of services and helpful free tips. Are you ready to conquer your blogging tech? WORDPRESS HELP & MAINTENANCE With years of experience as a WordPress blogger and web developer, Jessica offers a unique combination of skills to get your blog running seamlessly. FREE TIPS & TRICKS FOR BLOGGERS Subscribe and check back for step by step tutorials for difficult tasks and advice on plugins and tech tools from a seasoned WordPress blogger. NEW E-COURSES COMING SOON! Be the first to know about the launch of brand new e-courses designed to help bloggers and small business owners conquer their tech! CURRENTLY ACCEPTING REQUESTS FOR FREELANCE WORK WHAT I DO CHECK OUT MY SERVICES WordPress Migration & Makeovers Dying to get your blog on WordPress, but overwhelmed with how to do it? Sick of your old theme and ready for an upgrade? I've got you covered with migrations from any other platform, custom makeovers, and even setting up brand new blogs! Troubleshooting & Customization Did you update a plugin and everything broke? Weird error message you can't figure out? Or just have a small feature you want to add? Talk to me and I'll walk you through the fix or get you all set up! Host Maintenance Do you want to transfer to a new host? Can't figure out how to set up custom email addresses? Or just don't have time to handle hosting issues when they happen. Let's talk about host maintenance packages! HTML & CSS Coaching Want to learn HTML & CSS to modify your blog or website on your own? Talk to me about how I can provide one on one tips, training, and even homework assignments to turn you into an HTML pro! Are you ready to boost your blog or business with FREE technical tips? HOW I'M DIFFERENT I CARE ABOUT CUSTOMER SERVICE I have high standards for customer service, which I will absolutely hold myself to. You can expect timely responses and results. I love my clients and they are my top priority! Your happiness is key. I'M A BLOGGER TOO I've been blogging professionally since March 2013, so I know first hand of the joys and struggles of trying to have your blog stand out. Want more proof? You can find me over at www.beaglesandbargains.com. MY GOAL IS TO EMPOWER YOU I value you and your time, so I'm not here to waste it. My goal is super simple. I want bloggers and small business owners to feel more comfortable with web development and technology. DROP ME A LINE Want to learn more? Ready to set sail to a bigger and better blog? Click the button below for my contact form or shoot an email over to [email protected]JavaScript must be enabled in order for you to use this site. However, it seems JavaScript is either disabled or not supported by your browser. Enable JavaScript by changing your browser options, and then try again. These kits are designed to replace incandescent lamps with LED lamps in Exit signs. Each features slim
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(Photo by Joe Raedle/Getty Images) less RIO DE JANEIRO, BRAZIL - JUNE 21: German team fans watch their team play against Ghana on the screen setup at the Word Cup FIFA Fan Fest during on Copacabana beach June 21, 2014 in Rio de Janeiro, Brazil. ... more Fans cheer in support of the German national football team near the Brandenburg Gate in Berlin, Germany on June 21, 2014 during the public viewing of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less Fans cheer in support of the German national football team near the Brandenburg Gate in Berlin, Germany on June 21, 2014 during the public viewing of the FIFA World Cup 2014 group G football match Germany vs ... more Photo: AFP/Getty Images Fans cheer in support of the German national football team near the... Photo-6500869.88425 - Houston Chronicle Image 45 of 71 A German fan reacts during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less A German fan reacts during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP ... more Photo: AFP/Getty Images A German fan reacts during the public viewing near the Brandenburg... Photo-6500870.88425 - Houston Chronicle Image 46 of 71 Fans wave the German flag during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less Fans wave the German flag during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. ... more Photo: AFP/Getty Images Fans wave the German flag during the public viewing near the... Photo-6500871.88425 - Houston Chronicle Image 47 of 71 BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more BELO HORIZONTE, BRAZIL - JUNE 21: Iran fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: An Argentina fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: An Argentina fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more CUIABA, BRAZIL - JUNE 21: A Bosnia-Herzegovin fan shows her colours ahead of the 2014 FIFA World Cup Group F match between Nigeria and Bosnia-Herzegovina at Arena Pantanal on June 21, 2014 in Cuiaba, Brazil. (Photo by Matthew Lewis/Getty Images) less CUIABA, BRAZIL - JUNE 21: A Bosnia-Herzegovin fan shows her colours ahead of the 2014 FIFA World Cup Group F match between Nigeria and Bosnia-Herzegovina at Arena Pantanal on June 21, 2014 in Cuiaba, Brazil. ... more A fan takes a selfie before the start of the Group F football match between Nigeria and Bosnia-Hercegovina at the Pantanal Arena in Cuiaba during the 2014 FIFA World Cup on June 21, 2014. AFP PHOTO / JUAN BARRETO (Photo credit should read JUAN BARRETO/AFP/Getty Images) less A fan takes a selfie before the start of the Group F football match between Nigeria and Bosnia-Hercegovina at the Pantanal Arena in Cuiaba during the 2014 FIFA World Cup on June 21, 2014. AFP PHOTO / JUAN ... more Photo: AFP/Getty Images A fan takes a selfie before the start of the Group F football match... Photo-6500879.88425 - Houston Chronicle Image 54 of 71 BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more A Russian supporter cheers for her team ahead of the Group H football match between Belgium and Russia at The Maracana Stadium in Rio de Janeiro on June 22, 2014, during the 2014 FIFA World Cup. AFP PHOTO / GABRIEL BOUYS (Photo credit should read GABRIEL BOUYS/AFP/Getty Images) less A Russian supporter cheers for her team ahead of the Group H football match between Belgium and Russia at The Maracana Stadium in Rio de Janeiro on June 22, 2014, during the 2014 FIFA World Cup. AFP PHOTO / ... more Photo: AFP/Getty Images A Russian supporter cheers for her team ahead of the Group H... Photo-6500881.88425 - Houston Chronicle Image 56 of 71 A Belgium's fan poses as she waits for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro during the 2014 FIFA World Cup on June 22, 2014. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images) less A Belgium's fan poses as she waits for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro during the 2014 FIFA World Cup on June 22, 2014. AFP PHOTO / ... more Photo: AFP/Getty Images A Belgium's fan poses as she waits for the start of the Group... Photo-6500882.88425 - Houston Chronicle Image 57 of 71 Belgium's supporters cheer as they wait for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro
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247, 41990, 3213, 949, 6355, 342, 7842, 10185, 534, 8600, 444, 18, 38, 19, 35652, 7736, 13, 3560, 407, 1698, 8487, 14, 6820, 11781, 15, 831, 9079, 26295, 326, 27, 313, 18, 10, 1698, 8487, 638, 14, 21272, 275, 253, 5928, 273, 10185 ]	KRAS mutation was found to be associated with the absence of biological and clinical activity for the anti-EGFR antibody treatment. [7, 8, 14] Approximately 30% to 50% of colorectal tumors are known to have a mutated (abnormal) KRAS, indicating that up to 50% of patients with CRC might respond to anti-EGFR antibody therapy. However, 40% to 60% of patients with wild-type KRAS tumors do not respond. [1] In these patients, data suggest that mutated BRAF, which is present in 5% to 10% of tumors, can affect response to these agents. [5, 6, 10] To see complete information on Colorectal Cancer, please go to the main article by clicking here. Previous Next: Clinical Implications of the Genetic Mutations Several phase II/III randomized trials have revealed the favorable impact on survival associated with the administration of one of two currently available anti-EGFR antibodies (cetuximab [Erbitux], panitumumab [Vectibix]) in patients with KRAS wild-type. [7, 8, 9, 10] In July 2012, the indication for cetuximab was updated to specify treatment of KRAS mutation-negative (wild-type), EGFR-expressing, metastatic colorectal cancer as determine by FDA-approved tests (eg, therascreen KRAS RGQ PCR Kit). A careful read of the data from these and other trials clearly demonstrates that patients with mutated KRAS are unlikely to benefit from anti-EGFR antibody therapy. However, it is not clear that patients with KRAS wild-type will definitely respond, only that they have a reasonable opportunity to derive clinical benefit from the therapy. For example, in the panitumumab vs best supportive care trial, there were no responders in the mutated KRAS group randomized to the therapy and only a 17% partial response rate was noted in the KRAS wild-type group. [8] It is unclear to what extent the lack of response in KRAS wild-type patients is due to BRAF mutations, but current data suggest that mutated BRAF confers resistance to anti-EGFR therapy given beyond first-line treatment. A retrospective analysis of 113 patients who received cetuximab or panitumumab demonstrated that none of the KRAS wild-type patients with BRAF mutations responded to therapy, and that none of the responders had BRAF mutations. In addition, BRAF mutant patients showed prolonged progression-free and overall survival compared with BRAF wild-type patients. [5] Similarly, a retrospective pooled analysis of the two phase III cetuximab studies demonstrated that the best treatment outcomes were observed in patients with both KRAS wild-type and BRAF wild-type tumors, but there were too few patients with BRAF mutations to determine whether BRAF mutation status alone could predict response to therapy. [6] Finally, in the cetuximab plus FOLFIRI study, although mutated BRAF was associated with a poor prognosis, it did not independently predict response to treatment. [10] Thus, although results from these and other studies are compelling, there are as yet no prospective data that can definitively determine the role of BRAF status in response to EGFR inhibitor therapy. Based on these observations, it is vital that patients with metastatic CRC who are being considered for treatment with anti-EGFR antibody therapy should be tested for the presence of a KRAS mutation prior to the administration of therapy and that both cetuximab and panitumumab be initiated only in patients with KRAS wild-type. This will ensure that the therapy is not administered to patients who are unlikely to obtain benefit. [17, 18] In fact, NCCN Clinical Practice Guidelines recommend testing for KRAS mutations at the time of diagnosis of stage IV disease so as to better prepare an appropriate management plan in case treatment with an anti-EGFR antibody is later considered. [17] Cetuximab labeling specifies use in CRC KRAS wild-type tumors and panitumumab labeling states use is not recommended for treatment with KRAS mutations. BRAF mutation status should be determined only after KRAS wild-type is detected. [17] Testing for microsatellite instability and mismatch repair lends information for the option to use pembrolizumab for unresectable or metastatic colon cancer that has tested positive for microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) and has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. [12] Previous Next: Testing for the Genetic Mutations Testing for mutations in codons 12 or 13 of the KRAS gene can be performed on formalin-fixed, paraffin-embedded tissue from the primary tumor or a metastasis using a variety of methods. BRAF V600E mutation status is determined via PCR amplification and DNA sequence analysis or allele-specific PCR on formalin-fixed, paraffin-embedded tissue from the primary tumor or a metastasis. Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Genentech; Astra-Zeneca ; Clovis; Tesaro<br/>Received income in an amount equal to or greater than $250 from: Astra-Zeneca; Clovis; Genentech; Tesaro; Celgene<br/>Received consulting fee from Genentech; Received consulting fee from Cellgene; Received consulting fee from Crititech; Received consulting fee from Amgen.Bulldogs plan to use home-course advantage Published 1:00 pm, Friday, September 24, 2010 Photo: Courtesy Photo By Betsy Lewis Image 1of/1 Caption Close Image 1 of 1 Photo: Courtesy Photo By Betsy Lewis Bulldogs plan to use home-course advantage 1 / 1 Back to Gallery Fall golf is more about getting better for the spring than anything else, but after starting off with a third-place finish last week in the Hereford Invitational, the Plainview Bulldogs are looking to make a bit of a statement to some of their new District 3-4A opponents. The Dogs played with Dumas in Hereford, and this week at the Plainview Triangular they are matched up with Randall and Caprock. Head coach Mike Lewis wants his team to think about what their play in this early fall tournament could communicate to their district opponents. "I told them ‘You can set the tone for next spring by playing well now so these guys think Plainview is going to be tough to beat on its home course,' " Lewis said, adding that the Bulldogs will host one of the district tournaments in the spring. The Bulldogs are a young group this year with a couple of freshman on the roster - Thomas Wirth and Matt Jolly - who Lewis said he hopes gain some confidence and experience this fall. "Individually, I want all of them to do the best they can," Lewis said. "But mostly I want them to improve on the things we talk about in practice. Definitely, want them to focus on the short game, but each one of them has strengths and weaknesses." The three veterans on the team - Jacob Rogers, Trent Kinkaid and Tim Gonzales - were able to play in summer tournaments with the freshman and were able to develop a chemistry this summer that Lewis said he thinks will benefit the team. "These older guys knew the freshmen were going to help us out. I don't think they knew they were going to make us better so quick," Lewis said. In Saturday's triangular, Lewis expects his team to post a score near 300. "I'm thinking we should be around 304 or better," Lewis said. "That's a 76 average. They all know they can reach that because they've done it before, but if they shoot that or lower, then we get close to breaking 200." While it is a long time away, Lewis hopes his team can use this opportunity on their home course to develop some confidence for district competition in the spring. "I want the guys to know they have the ability to get to regionals," Lewis said. "Of course, that's way down the road, but if we can have some success early and get some confidence in them, it will be easier in the spring." (Contact Ryan Thurman at 806-296-1355 or [email protected]. Become his fan on Facebook.)The hepatitis C virus (HCV) is an important pathogen that has infected approximately 170 million people worldwide. In spite of extensive efforts, surprisingly little is known about the mechanism by which HCV initiates infection. The lack of vaccine or effective therapy against this virus stresses the urgent need for studies of HCV entry into host cells. HCV is an enveloped virus that enters cells via a clathrin-mediated pathway and releases its nucleocapsid by fusing the viral membrane with an endosomal membrane a process that is promoted by HCV E1 and E2 glycoproteins. The fusion induced by E1E2 is strictly receptor- and low pH-dependent. Not only is the mechanism of this process poorly understood, but even the identity of the fusion protein (E1 vs. E2) has not been established. This is due to the lack of a tractable model system to study HCV fusion. Our working hypothesis is that HCV fusion precedes through at least two major steps - a priming step through interactions with cellular receptors which render E1E2 fusogenic, followed by low pH-dependent fusion. This hypothesis predicts that: (1) low pH pre-treatment in the absence of receptors
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$5_{6(j+1)}, 12_{6j},13_{6j}$, move $9_{6(j+1)}$ to stack $R$ to reach the configuration in Fig. \[fig:Premoved2\], which we can sort by Lemma \[lem:can\_sort1\]. If $j=i$ then the remaining input is just $S_i=(14\ 15 \ 11)_{6i}$: move $14_{6i},15_{6i}$ to stack $R$, then output all entries. If one of $ 12_{6j},13_{6j}$ is missing, use the same procedure ignoring the missing entry. \[prop:GiBases\] Let $G_i'$ be a permutation obtained by removing a single entry from $G_i$. Then $G'_i\in S(3,\infty)$. We give a deterministic procedure to sort $G_i'$. There are three cases depending on from where the entry is removed. Term removed from $P$. Let $P'$ be the factor $P$ with one entry removed. We claim that there is a sorting sequence for $P' x_0$ which outputs the smallest six items in order and leaves $10,9$ in stack $R$. To show this we simply consider all cases. 1. If $1$ is removed, $2,4,3$ can be output in order, then $7,6$ placed in stack $L$, $10$ in stack $R$, then $5,6,7$ output, and $9$ placed on top of $10$ in stack $R$. 2. If $2,3$, or $4$ are removed, write $P'=ab761$ with $a,b\in\{2,3,4\}$. Place $a,b$ in stack $R$, move $7,6$ into stack $L$, output $1$, then output $a,b$ in the correct order, then move $10$ into stack $R$, output $5,6,7$ and move $9$ into stack $R$. 3. If $6$ or $7$ is removed, write $P'=243a1$ with $a\in\{7,6\}$. Place $4,3,2$ in stack $L$ in order, move $a$ into stack $R$, output 1 then $2,3,4$, then move $a$ into stack $L$, move $10$ into stack $R$, output $5,a$ and move $9$ into stack $R$. Thus after inputting $P'x_0$ we have the configuration shown in Fig. \[fig:Premoved2\] with $j=0$, which we can sort by Lemma \[lem:can\_sort1\]. Term removed from $x_s, 0\leq s\leq i$. Input $P$ leaving $6,7$ in stack $R$, which brings us to the configuration in Fig. \[fig:67\] with $j=0$. Now assume we have input $P\dots x_{j-1}y_{j-1}$ with $j\leq s$ (note the convention that $x_{-1},y_{-1}$ are empty) and the configuration is as in Fig. \[fig:67\]. (0,1.7) – (0,-2.5) – (1,-2.5) – (1,1.7); (2.5,-.5) node [$R$]{}; (1.8,1.7) – (1.8,0) – (3.2,0) – (3.2,1.7); (0.5,-3) node [$L$]{}; (4,2.4) – node\[above\] (2.66,2.4) – (2.66,1.7); (5.8,2.4) node [$x_j\ y_j\dots \text{ or } x_s'y_s\dots $]{}; (2.33,1.7) – (2.33,2.4) – node\[above\] (0.66,2.4) – (0.66,1.7); (-1.2,2.4) – node\[above\] (0.33,2.4) – (0.33,1.7); (2.5,.8) node [$12_{6(j-1)}$]{}; (2.5,0.3) node [$13_{6(j-1)}$]{}; If $j<s$ we can input $x_jy_j$ into the stacks to arrive at the same configuration with $j$ incremented by $1$, as follows: move $10_{6j}$ to stack $L$, output $5_{6j},6_{6j}=12_{6(j-1)},7_{6j}=13_{6(j-1)}$, move $9_{6j}$ to stack $L$, move $13_{6j},12_{6j}$ to stack $R$, output $8_{6j},9_{6j},10_{6j}$. If $j=s$, we proceed as follows: 1. If $5_{6s}$ removed, output $6_{6s}=12_{6(s-1)},7_{6s}=12_{6(s-1)}$, move $9_{6s},10_{6s}$ to stack $R$, to reach the configuration in Fig. \[fig:Premoved2\] with $j=s$. From here the remaining entries can be sorted by Lemma \[lem:can\_sort1\]. 2. If $10_{6s}$ is removed, output $5_{6s}, 6_{6s}, 7_{6s}$ and place $9_{6s}$ in stack $R$, to reach the configuration in Fig. \[fig:Premoved2\] with $j=s$ and $10_{6s}$ missing. From here the remaining entries can be sorted Lemma \[lem:can\_sort1\]. 3. If $9_{6s}$ is removed, move $6_{6s}$ to stack $L$, move $10_{6s}$ on top of $7_{6s}$ in stack $R$, output $5_{6s}, 6_{6s}$, move $13_{6s}, 12_{6s}$ into $L$, then output $8_{6s}, 10_{6s}$. This gives the configuration in Fig. \[fig:67\_2\] with $j=s$. From here the remaining entries can be sorted by Lemma \[lem:can\_sort2\]. Term removed from $y_s, 0\leq s\leq i$ or $S_i$. Input $Px_0$ to reach the configuration in Fig. \[fig:Si\_removed\] with $j=0$: move $2,3,4$ into stack $L$, $7,6$ to $R$, output $1,2,3,4$, move $10$ into $L$, output $5,6,7$ then move $9$ into $L$. (0,1.7) – (0,-2.5) – (1,-2.5) – (1,1.7); (2.5,-.5) node [$R$]{}; (2,1.7) – (2,0) – (3,0) – (3,1.7); (0.5,-3) node [$L$]{}; (4,2.4) – node\[above\] (2.66,2.4) – (2.66,1.7); (2.33,1.7) – (2.33,2.4) – node\[above\] (0.66,2.4) – (0.66,1.7); (-1.2,2.4) – node\[above\] (0.33,2.4) – (0.33,1.7); (0.5,-1.8) node [$10_{6j}$]{}; (0.5,-1.3) node [$9_{6j}$]{}; Now suppose we have input $P x_0 y_0\ \dots \ x_{j}$ to reach the configuration in Fig. \[fig:Si\_removed\]. If no entry is removed from $y_j$ and $j<i$ then we can input $y_jx_{j+1}$ to return to the configuration in Fig. \[fig:Si\_removed\] with $j$ incremented by $1$ as follows: move $13_{6j},12_{6j}$ to stack $R$, output $8_{6j},9_{6j},10_{6j}$, move $10_{6(j+1)}$ to $L$, output $5_{6(j+1)}=11_{6j}, 12_{6j}, 13_{6j}$, then move $9_{6(j+1)}$ to stack $L$. If $j=s$ ($y_s$ is removed): 1. If $8_{6s}$ is removed, output $9_{6s},10_{6s}$, move $
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8539, 1156, 2073, 44066, 366, 5137, 187, 50276, 36955, 2073, 2915, 15, 5996, 14, 881, 14, 18569, 64, 19261, 8539, 8606, 30932, 5996, 64, 8581, 4500, 60, 2877, 568, 45410, 9686, 8539, 1156, 2073, 688, 4507, 5137, 187, 50276, 36955, 2073, 2915, 15, 5996, 14 ]	ikipedia page for the maths. Birthday_problem My approach: Generate random numbers in range [0 - 364] add them to a set until a duplicate is generated (set.add returns false) add the count (or set size) to a list repeat this X-times calculate the average of the list Code: public static void main(String[] args) { List<Integer> list = new ArrayList<>(); for(int i = 0; i<10000; i++){ int count = 0; Set<Integer> set = new HashSet<>(); while(set.add(ThreadLocalRandom.current().nextInt(0, 365))){ count++; } list.add(count); } double avg = list.stream().mapToInt(Integer::intValue).average().getAsDouble(); System.out.println(avg); } My output is always under 24. E.g 23.6285 I've tried to run the for-loop 1000, 10000, 1000000 times I've tried ThreadLocalRandom.current().nextInt(0, 365), nextInt(0, 364), nextInt(0, 366) I've tried list.add(count); and list.add(set.size()); But I'am getting always an average < 24. Mostly something like 23.629237. Do you see any mistakes and why I'am not getting the correct value, which is approx. ≈24.61659? A: Note that your answer is almost exactly 1 less than the expected. That's a clue: it tells you that you're probably under-counting by 1, which is a very common bug. Consider your condition: while(set.add(<newPersonsBirthday>)){ count++; } That won't count the last person! They won't be added to the count, and so you're not including them in the set of people in the room. You've counted everybody in the set except the person who triggered the match -- but they're part of the set. Just add count + 1 to your list, to account for that person. Q: Elasticsearch filter results excluding by id I need to return results that do not include docs with certain ids. Elasticsearch allows us to specify which ids are allowed but I see no way to disallow certain ids. In my case I want to not return things the user has already seen so the list will be different for each user. A: You can achieve this by adding a bool/must_not filter containing an ids filter with an array of ids you don't want to appear, like this: { "query": { "bool": { "must": [ ... <--- your other filters go here ], "must_not": [ { "ids": { "values": [ "id1", "id2" <--- add all the ids you DON'T want in here ] } } ] } } } Chikungunya infection is caused due to the chikungunya virus which is transmitted to humans by the bite of infected mosquitoes. The virus is spread by the female species of two different kinds of mosquitoes namely, Aedes aegypti and Aedes albopictus. The origin of Chikungunya dates back to the 1950s in Tanzania. In Makonde, the word loosely translated to “walking bent over”. This is because the virus causes severe joint and muscle pain making the patient walk bent over due to back pain. Chikungunya was once considered to be a disease of the tropics. However, now cases have been documented in well over one-quarter of the countries around the globe. Chikungunya is a major health issue in India affecting billions. After 2010, India saw a decline in the instances until 2016, when a massive outbreak nudged the country severely. Signs and Symptoms It takes around 3 to 7 days after a person is bitten by chikungunya mosquitoes for signs and symptoms to show up. The most common symptoms are fever which can be as high as 104 °F and severe joint pain. Chikungunya may not be a deadly infection but the symptoms can be disabling and severe. Other symptoms include muscle pain, headache, tiredness, rash or joint swelling. Less common symptoms include vomiting, nausea, conjunctivitis, and maculopapular rash. These symptoms are short-lived. Most people start to recover within a week’s time. A majority of infections can cause arthritis and arthralgia months or years after the initial infection. Who are More at Risk? Newborn babies who get infected with the virus are at risk of suffering from a more severe form of this ailment. Elderly people due to weak immunity and those with medical conditions such as heart disease, diabetes or high blood pressure are also more susceptible to chikungunya. The silver lining to this ailment is that once a person has suffered from chikungunya, the risk of getting it again is extremely low as the person becomes immune to it. Diagnosis Chikungunya symptoms are similar to Zika and dengue. These diseases are also transmitted by the bite of the same mosquitoes that spread chikungunya. Thus, sometimes chikungunya is misdiagnosed especially in those areas where all these diseases are common. It is extremely important to rule out dengue fever at the earliest due to its higher mortality rate than chikungunya. Visit a doctor as soon as you suspect having chikungunya symptoms or if you have visited a place recently where chikungunya is prevalent. Since the definitive diagnosis can be done only by running blood tests due to the similar nature of the symptoms with other conditions, the doctor may advise getting some tests done. Complications There are certain complications that may arise when a person suffers from chikungunya. These include: Uveitis Retinitis Meningoencephalitis Myocarditis Hepatitis Guillain-Barré syndrome syndrome Cranial nerve palsies Nephritis Hemorrhage Myelitis Is There Any Vaccine Available? Unfortunately, there is no vaccine to prevent or treat chikungunya. India and the United States of America are continuing with their research to develop it. Treatment There is no specific treatment for this ailment. Generally, people get better by themselves within 7 days and recover completely thereafter. However, joint pain may take much longer to get better. Doctors offer treatment for symptomatic relief with fever and pain medicines. The patient must drink plenty of fluids to prevent dehydration and take plenty of rest to get better sooner. If you or a dear one exhibit symptoms of chikungunya, get checked today. Nightingales offer home-based medical services ranging from doctor consultation to laboratory services. To know more about how we can help or to book a test, consult a Doctor at home, visit us at https://www.nightingales.in/ Reference – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682881/ Image Credits – People photo created by freepik – www.freepik.comjQuery(window).load(function() { pf_switch_status_look(); console.log('Loaded: PressForward Alterations'); jQuery('body.post-type-pf_feed').on('click', '.edit-post-status', function(){ console.log('click edit status'); pf_switch_status_look(); }); jQuery('body.post-type-pf_feed').on('click', '.save-post-status', function(){ console.log('save edit status'); pf_switch_status_look(); }); jQuery('body.post-type-pf_feed').on('click', ".refresh-feed", (function(evt){ evt.preventDefault(); var element = jQuery(this); console.log('Refreshing feed.'); console.log( element ); var feed_id = element.attr('data-pf-feed'); jQuery.post(ajaxurl, { action: 'ajax_update_feed_handler', feed_id: feed_id }, function(response) { //jQuery('.loading-'+itemID).hide(); //jQuery(".result-status-"+itemID+" .msg-box").html(response); //alert(response); //jQuery("#test-div1").append(data); }); }) ); }); function pf_switch_status_look(){ jQuery('body.post-type-pf_feed #submitdiv h3.hndle span').text('Activate'); jQuery('body.post-type-pf_feed').find('#post_status option[value="draft"]').text('Inactive'); jQuery('body.post-
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(\[eq:delta\_theta\]), the angular fluctuations are given by $$\delta\Theta^2 = 4\, (\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]})(\ell_{[\gamma}A_{\delta ][ \rho}\ell_{\sigma]})s^{\alpha}k^{\beta}t^{\mu}k^{\nu}s^{\gamma}k^{\delta} t^{\rho}k^{\sigma}F(\omega_g,s,t_0).$$ Interestingly, since $F(\omega_g,s,t_0)$ is independent of the displacement parameter, $\alpha$, so are $\delta\xi^2$ and $\delta\Theta^2$. Therefore, the fluctuations depend only on the squeezing parameter, $\zeta$, and we can immediately say that a coherent state (classical wave) for which $\zeta=0$ induces no fluctuations. For the following calculations, we assume the passing gravity waves are in the Transverse Tracefree (TT) Gauge. However, note that since our results derive from the Riemann tensor, the equations are gauge invariant, and we use the TT gauge only for calculational convenience. To begin, note that if the gravity waves and photons travel in parallel, then one finds $(\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]}) t^{\alpha}k^{\beta}t^{\mu}k^{\nu} = 0$. This indicates that there is no induced redshift fluctuation nor angular blurring due to a squeezed state gravity wave traveling with the photons. This is as one might expect, since a gravity wave in the TT gauge has only non-zero transverse components. We may subsequently restrict our attention to transversely propagating gravity waves and will assume the gravity waves to propagate with $\ell^{\mu}=\omega_g(1,0,0,1)$ while the photons continue to have wave vector $k^{\mu}=(1,1,0,0)$. We define $$\mathfrak{F}(\omega_g,s,t_0)= [1-\cos(\omega_g s)][1-\cos(\omega_g t_0)] [\cosh(2r)-\sinh(2r)\cos(\theta-\omega_g(t_{0}+s))-1]\, ,$$ so that for a gravitational wave propagating in the z direction, for which $\ell_x=0$, $$F(\omega_g,s,t_0) = \frac{16}{{\omega_g}^4}\mathfrak{F}(\omega_g,s,t_0) \,.$$ ### Redshift Fluctuations {#rfcase} With transversely propagating gravity waves, $$(\ell_{[\alpha} A_{\beta ][ \mu} \ell_{\nu]})t^{\alpha}k^{\beta}t^{\mu}k^{\nu} = -\frac{1}{4}\omega_g^2 A_{+}\, ,$$ and therefore $$\label{rfcase2eq} \delta\xi^2 = 4\, A_{+}^2 \mathfrak{F}(\omega_g,s,t_0).$$ There exists a non-zero effect which in this case depends only on the $(+)$ polarization. For a gravity wave propagating in the $z$-direction, $A_+ = A_{xx} =-A_{yy}$. ### Angular Blurring {#abcase} #### Case 1 Let the photons propagate in the x direction while the gravity waves propagate in the z direction and probe the y component of angular blurring, $s^{\mu}=(0,0,1,0)$. We find $$(\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]})s^{\alpha}k^{\beta}t^{\mu}k^{\nu} = \frac{1}{4}\omega_g^2 A_{\times}$$ and $$\label{abcase2eq} \delta\Theta_y^2 = 4\, A_{\times}^2\mathfrak{F}(\omega_g,s,t_0).$$ Note that here the y component of blurring depends only on the $(\times)$ polarization of the gravity waves. Here $A_{\times} = A_{xy}=A_{yx}$. #### Case 2 To probe the z component of blurring, set $s^{\mu}=(0,0,0,1)$. The result is $$\label{abcase3eq} \delta\Theta_z^2 = 4\, A_{+}^2\mathfrak{F}(\omega_g,s,t_0)\, ,$$ which is the same as Eq. (\[rfcase2eq\]) for redshift fluctuations, and only depends on the $(+)$ polarization of the gravity waves. Classical Time Dependent Variation ---------------------------------- As noted above, the fluctuations in redshift and angle depend upon the degree of squeezing, measured by the parameter $\zeta$. In this subsection, we will examine the expectation value of the change in fractional redshift, $\langle\Delta\xi\rangle$ and in angle, $\langle\Delta\Theta\rangle$. These quantities will depend only upon the displacement parameter $\alpha$, and hence would be the same in the coherent state $\|\alpha,0 \rangle$ as they are in the squeezed state $\|\alpha,\zeta \rangle$. For this reason, we regard these quantities as giving the classical time-dependence. Alternative approaches to the classical time-dependence of these quantities may be found in Refs. [@Weber; @Zipoy; @Kaufmann] Here it is possible to calculate $\langle\Delta\xi\rangle$ as a single integration of the Riemann tensor over the spacetime region $da$ via Eq. (\[RateOfChange\]). However, for comparison purposes, we calculate $\langle\Delta\xi\rangle^2$ directly. In this case, $$\langle\Delta\xi\rangle^2 = \int da \int da' \,\langle\hat{R}_{\alpha\beta\mu\nu}(x)\rangle \langle\hat{R}_{\gamma\delta\rho\sigma}(x')\rangle t^{\alpha}k^{\beta}t^{\mu}k^{\nu}t^{\gamma}k^{\delta}t^{\rho}k^{\sigma}\, ,$$ where now $$\langle\hat{R}_{\alpha\beta\mu\nu}(x)\rangle \langle\hat{R}_{\gamma\delta\rho\sigma}(x')\rangle = 4 \sum_{l} (\ell_{[\alpha} A_{\beta][\mu}\ell_{\nu]})(\ell_{[\gamma} A_{\delta][\rho}\ell_{\sigma]}) f'(x,x')$$ with $$f'(x,x') = \alpha^2 e^{i\ell_{\tau} (x^{\tau}+x^{\prime\tau})} + (\alpha^{\ast})^2 e^{-i\ell_{\tau} (x^{\tau}+x^{\prime\tau})} + 2\vert\alpha\vert^2\cos[\ell_{\tau} (x^{\tau}-x^{\prime\tau})].$$ Integration of $f'(x,x')$ over the spacetime region of Fig. \[spacetime\] yields $$\begin{aligned} & & F'(\omega_g,s,t_0) = \int da \int da' \, f'(x,x') = \nonumber \\ & & \frac{16\{1-\cos[s(\ell_x-\omega_g )]\} [1-\cos(\omega_g t_0)]} {\omega_g^2(\ell_x-\omega_g)^2} \left(\alpha e^{\frac{i}{2}[\ell_x s-\omega_g(s+t_0)]} + \alpha^{\ast} e^{-\frac{i}{2}[\ell_x s-\omega_g(s+t_0)]}\right)^2.\end{aligned}$$ Thus the classical time variation of the redshift is characterized by: $$\label{classical} \langle\Delta\xi\rangle^2 = 4\, F'(\omega_g,s,t_0) (\ell_{[\alpha} A_{\beta][\mu}\ell_{\nu]})(\ell_{[\gamma} A_{\delta][\rho}\ell_{\sigma]}) t^{\alpha}k^{\beta}t^{\mu}k^{\nu}t^{\gamma}k^{\delta}t^{\rho}k^{\sigma}.$$ For the case of redshift variations with photons and a gravity wave propagating perpendicularly (Sect. \[rfcase\]), $$\label{rfclassical} \langle\Delta\xi\rangle^2 = 4 \,A_{+}^2 \mathfrak{F'}(\omega_g,s,t_0).$$ Here $\mathfrak{F'}(\omega_g,s,t_0)$ is defined in a similar way as $\mathfrak{F}(\omega_g,s,t_0)$ when $\ell_x=0$, $$\mathfrak{F'}(\omega_g,s,t_0) = [1-\cos(\omega_g s)][1-\cos(\omega_g t_0)] \left(\alpha e^{-\frac{i\omega_g}{2}(s+t_0)} + \alpha^{\ast} e^{\frac{i\omega_g}{2}(s+t_0))}\right)^2.$$ The classical time variation of angular position yields similar results. Particularly, for perpendicularly propagating photons and
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816, 984, 13, 10571, 13 ]	all-around gain the nation could reap from the adoption and application of biotechnology cannot not be overemphasized, she said. Categories<!DOCTYPE html> <!-- DO NOT EDIT! This test has been generated by /html/canvas/tools/gentest.py. --> <title>OffscreenCanvas test: 2d.state.saverestore.transformation</title> <script src="/resources/testharness.js"></script> <script src="/resources/testharnessreport.js"></script> <script src="/html/canvas/resources/canvas-tests.js"></script> <h1>2d.state.saverestore.transformation</h1> <p class="desc">save()/restore() affects the current transformation matrix</p> <script> var t = async_test("save()/restore() affects the current transformation matrix"); var t_pass = t.done.bind(t); var t_fail = t.step_func(function(reason) { throw reason; }); t.step(function() { var offscreenCanvas = new OffscreenCanvas(100, 50); var ctx = offscreenCanvas.getContext('2d'); ctx.fillStyle = '#0f0'; ctx.fillRect(0, 0, 100, 50); ctx.save(); ctx.translate(200, 0); ctx.restore(); ctx.fillStyle = '#f00'; ctx.fillRect(-200, 0, 100, 50); _assertPixel(offscreenCanvas, 50,25, 0,255,0,255, "50,25", "0,255,0,255"); t.done(); }); </script> If you grew up watching football, you likely know where most of the color-commentary broadcasters came from. Think of John Madden. Just about everyone knows that he started as a player in the National Football League. He later went on to coach the Oakland Raiders to a Super Bowl before his long career commentating on games. What I didn’t know is that story just about sums up Marcus Graham’s career. Better known under his “djWheat” pseudonym, Graham is an e-sports commentator, online talk-show host, and business professional in e-sports and online broadcasting. I knew of him from watching a few StarCraft II matches and from his Live On Three e-sports show that I’ve watched a few times. As a relative outsider to e-sports, I always thought that Graham woke up one day, saw how big e-sports is getting, and decided to take a crack at broadcasting it. The truth is that he was doing this job before we even had a name for it. “I’m an older guy,” said Graham. “A lot of people don’t necessarily know the history. They’re like, ‘Why is this guy even qualified to talk about video games on any level?’ Before there was broadcasting — before people were even considering broadcasting these types of events we do now — I was a player.” Graham got his start in competitive gaming — this was before anyone had coined the term “e-sports” — as a player on one of the top-ranked North American Quake II team-deathmatch teams. He was the leader of Clan 519, and he would travel with his team and compete in LAN parties for money. Image Credit: Graham “I have a huge competitive fire inside me,” he said. “The interest in playing was always there.” As Graham got into his 20s, he began to put that fire aside in favor of something that he could support himself with. “One day, as I was about 21-years old, I said to myself, ‘You know what? I love to play video games. I really love to play Quake and travel around the U.S. and compete,” said Graham. “But the fact of the matter is, I’ve gotta get a job. And I’ve gotta get a job fast. At the time I was very PC-centric. I happened to get a job with a tech company right around the Y2K boom, when they were hiring anyone who knew anything about computers. This was great for me, because it allowed me to have a full-time job, and then when I wasn’t working, I was playing and doing what I could for the team.” For Graham, doing what he could meant taking on the role of de facto coach. He decided one of the best ways he could do this was to watch the games and comment over them. That way he could call out smart moves and help the other players work on recognizing and addressing their errors. “I probably did three or four of these before one of my guys came to me and said, ‘I don’t know if the other guys are actually listening to what you’re doing, but you should try to do this like it’s a sports game. Try to commentate. Your passion is obviously strong enough there. You’re almost doing it already.'” The idea immediately took root in Graham’s imagination, and he began researching how he would go about doing something like that. “I looked for different technology,” he said. “This was about 1999 into 2000, and so the first technology I ever used to stream was actually a RealAudio server. I could have 25 people, max capacity, listening. I filled it up every night, and I thought I was just the bee’s knees because there were 25 people interested in hearing about these Quake games that were happening.” RealAudio is a streaming audio codec that individuals can use to stream music and audio content over the web. RealNetworks designed it specifically for low-bandwidth connections like dial-up modems. As fun as it was, the 25-person limit forced Graham to move on to other technology. That’s when he found WinAmp’s Shoutcast software. Shoutcast was similar to RealAudio, but it provided the opportunity for Graham and others to host Internet “radio stations” that could handle up to 1,000 simultaneous listeners. “That’s what ended up happening,” he said. “I started doing, independently, my own radio broadcasts for Quake. I eventually ended up joining a group of guys that were called TSN, the Team Sportscast Network. They did the same thing, where they had their own servers. I was their Quake broadcaster.” The Team Sportscast Network covered a wide variety of games although it specialized on the Tribes franchise. The format was so popular in certain gaming circles that a lot of people still refer to game commentators as “shoutcasters.” “I ended up leaving that place and starting my own little station called Inside the Game,” said Graham. “But TSN was kind of the start of it all.” The first commentator In 1999, a handful of people were starting to use platforms like Shoutcast to talk about competitive games. That’s also when people started commentating live matches, but Graham says it is difficult to know who was first. “I think there were a lot of examples of people doing [commentary] where they didn’t even realize they were doing it,” he said. “For that reason, it is really hard to pinpoint who was the first person that was actually out there broadcasting these things. I’ve been labeled that guy several times, but I don’t even know that I can take that credit.” It wasn’t until 2002, says Graham, when companies like MLG were founded, that a wider audience began to realize that game commentators were a real thing. “I think that was the first year that this hobbyist activity really became a reality.” Before it was cool … or profitable The early days of game broadcasting and commentating were very different. Today, organizations like MLG have full-time play-by-play, analyst, and color-commentary people. Those companies keep many of them on salary, fly them out to events, and even get them tailored suits. Those are the kinds of things that Graham rarely received and most of the time had to pay for himself at the beginning. “On the one hand, I was the talent,” he said. “I was the guy who got on the microphone and did his thing. But at the same time, because I was so into computers and so into the technical aspects of broadcasting, I often played the roles of talent, producer, and director all at the same time. The challenges were ridiculously hard.” Graham was essentially running his own production company as a hobby. He and his team would have to drag thousands of dollars worth of equipment to events around the country and ask organizers to provide tables, Internet access, and access to the game. This was all before video streaming. Hell — this was before YouTube. Graham would set up a situation similar to what an AM radio network has at a sports arena. He would set up a beefy audio-streaming station and watch the game and broadcast over it. Ideally, gamers would also watch the game, typically Quake, through a spectator mode in the title itself as well. “But the logistics were kind of like, us knocking on companies’ doors and saying: ‘Hey! This is a cool thing that we do. Let us come to your place and do it.’ We paid our way for years to events. That was just because, partially,
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The information provided through TheBodyPRO.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.1. Field of the Invention The present invention relates to a suspension arrangement for a hydraulic elevator. 2. Description of the Background Art At present, conventional hydraulic elevators are implemented as rucksack-type elevators in which the elevator car is mounted on a supporting frame resembling a rucksack. As to their suspension, these elevators are either of a direct-acting or an indirect-acting type. Direct-acting elevators of normal construction without an expensive telescopic cylinder are only applicable in low-rise buildings where the elevator only serves one or two floors. Therefore, most hydraulic elevators employ an indirect-acting type of suspension. Such elevators usually have a hoisting height of 3.5-15 m, corresponding to 2-6 floors. The maximum hoisting height is about 20 m. In an indirect-acting elevator, a hoisting rope attached to a fixed column is passed over a diverting pulley mounted on top of the piston and further to the car frame supporting the elevator car. Due to this roping, the car travel equals twice the stroke of the piston, which is why this type of suspension is termed 2:1 suspension. However, this widely used suspension system has certain serious drawbacks. First, since the length of the cylinder (and the piston inside it) equals at least half the entire hoisting height, difficulties are encountered in transporting such a long cylinder into the elevator shaft. The cylinder is usually brought into the shaft via its door opening, in which case the cylinder may be at most about as long as the guide rail bar, i.e. about 5 m. This limits the hoisting height to 10 m, corresponding to four floors. When larger hoisting heights are to be achieved, the cylinder has to be hoisted into the shaft via the top of the shaft. However, this is only possible at an early stage of the construction work, and it is necessary to schedule the transport and hoisting of the cylinder into the shaft accordingly. This causes extra work and expenses. Moreover, the cylinder has to be protected in the shaft during construction, and it is always more or less of a hindrance to other work. Another solution applied in the case of large hoisting heights is to use an extendable cylinder. In this case, the cylinder is composed of two sections which are only joined together in the shaft. However, because of the threaded joint, the cylinder has to be manufactured from a thicker tube than a jointless one. Because of the joint, the manufacture of the cylinder and especially its final grinding is an elevator- and cylinder-specific and expensive job. The testing of the cylinder also requires special arrangements, and joining the cylinder sections and installing the cylinder in a narrow and dirty space is difficult and expensive. A jointed cylinder costs at least one and a half times as much as a jointless one. Another limitation in the case of 2:1 suspension, in addition to the problem of moving the cylinder into the shaft, is the risk of buckling of the piston tube at larger hoisting heights. This limits the hoisting height and makes it necessary to increase the thickness of the wall of the piston tube. However, this increases the weight of the piston, thus reducing the usable hoisting capacity of the cylinder. Moreover, due to the material costs, this is an expensive solution. Another way to solve the buckling problem is to use reinforcements to prevent buckling, but this also involves additional costs.Small intestinal development in growth-retarded fetal sheep. The functional maturity of the gastrointestinal system is essential for the survival of the neonate. The effects of reducing placental size and the ensuing fetal growth retardation on the development of the small intestine (SI) of the sheep fetus were investigated. At 140 days of gestation (term is 147 days), fetal body weight, gastrointestinal weight (from the abomasum to the rectum, i.e., the gut), SI weight, and SI length in the growth-retarded fetuses (n = 6) were significantly reduced (p less than 0.05) when compared with age- and breed-matched control fetuses. The SI weight was disproportionately reduced as a fraction of the gut weight or SI length (p less than 0.01). The proximal SI showed marked reductions in the thickness of the wall, muscularis externa, mucosa, villus height, and crypt depth (p less than 0.003). Densities of villi and crypts were also reduced (p less than 0.02). The crypt-to-villus ratio was maintained. Glycogen was accumulated basally in the villus epithelial cells, and their nuclei were located apically. These characteristics are comparable to those of much younger fetuses. In the distal SI, interanimal variation was large; however, the mean thickness of the wall, the muscularis externa, the mucosa, and the villus height were all reduced (p less than 0.05). In this region, the density of villi and crypts, the pattern of glycogen accumulation, and the position of the nuclei did not markedly differ between growth-retarded and control fetuses. Villus cell density was increased (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS) #----------------------------------------------------------------------------- # _MatchMac # # Takes any number of MAC addresses and attempts to find a matching comment # in the "ethernetMACs.txt" file. #----------------------------------------------------------------------------- sub _MatchMac(IN string $macs, OUT string %macTypes) { string $macFile = "ethernetMACs.txt"; @echo off; @record on; ifnot (`getdirectory -scripts`) { echo "* MatchMac: Unable to get scripts directory"; return false; } @record off; string $dir = GetCmdData("dir"); ifnot (defined($dir[0])) { echo "* MatchMac: Unable to retrieve scripts directory"; return false; } string $lines; ifnot (ReadFile("$dir\\..\\$macFile", $lines)) { echo "* MatchMac: Error reading MAC listing file"; return false; } int $numLines = sizeof($lines); if ($numLines == 0) { echo "* MatchMac: No matching lines in MAC listing file"; return false; } string $line; foreach $line ($lines) { string $addrs = Split(":", $line); if (sizeof($addrs) > 2) { # good line string $mac; foreach $mac ($macs) { string $macParts = Split(" ", $mac); if ((sizeof($macParts) == 6) && ($macParts[0] == $addrs[0]) && ($macParts[1] == $addrs[1])) { string $last = Split(" ", $addrs[2]); if ((sizeof($last) > 1) && ($last[0] == $macParts[2])) { # we have a match %macTypes{'$mac'} = $last[1]; } } } } } return true; } /* end _MatchMac */Availability: Normally ships in 10 days Part Number:CI-FT-218 Quantity Description The St. Aubin Wall Garden Fountain is the perfect choice for your home, garden, patio, or other social gathering area. Water flows out the decorative center of the flower detail on the top of the back piece of the Wall Fountain. The St. Aubin Wall Fountain will make the perfect center piece. Color shown is Alpine Stone. The patinas are designed to replicate the look of natural aging, but unlike a painted finish, the patinas do not prevent the natural aging process. Any cast stone item with a patina finish will weather naturally in an outdoor environment. Because each patina is hand applied in a multi-step process and the product is photographed in natural settings, actual colors may vary. The acid stains create a bold, new look. These rich multi-dimensional colors bring a new depth and dimension to the cast stone product. The mixture of water, metallic salts, and muriatic acid create permanent stains in the surface of the concrete which will not flake or peel. Like stains for wood, each piece will accept the stain in varying degrees of intensity, creating natural color variations that brings character and distinction to each peace. NOTE: This product includes special ordering instructions. Please read the 'Special Ordering Instructions' section above before placing an order.#!/usr/bin/python # coding=utf-8 # # Copyright 2003 Sandia Corporation. # Under the terms of Contract DE-AC04-94AL85000, there is a non-exclusive # license for use of this work by or on behalf of the # U.S. Government. Redistribution and use in source and binary forms, with # or without modification, are permitted provided that this Notice and any # statement of authorship are reproduced on all copies. # from __future__ import
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20971, 894, 313, 7722, 10, 1955, 281, 697, 973, 14, 4304, 2554, 275, 253, 1794, 14, 21285, 267, 5511, 875, 253, 7026, 285, 11219, 2718, 15, 6915, 18311, 505, 957, 1546, 1783, 13, 359, 1119, 271, 2559, 1180, 273, 372, 28859, 2907, 353, 6072, 275, 2810, 18326, 281, 11083, 13154, 275, 9813, 1363, 672, 2429, 342, 440, 17159, 5760, 15, 844, 671, 36325, 1243, 353, 6072, 323, 253, 767 ]	: Adobe Homes in the Desert" Host David Yetman and expert architect Bob Vint travel around Tucson, Arizona, to see how adobe - the perfect desert building material - was used in the past and is still used today. Adobe not only has a remarkable period of longevity, but also has thermal capabilities, making it ideal for the hot dry desert. Yetman and Vint spend time at the San Xavier Mission to watch a restoration crew use new adobe to repair and restore the existing adobe exterior. D 7:30 am Kevin Dundon's Modern Irish Food"Transformations" Kevin serves up a crock of Kilmore Quay mussels with bacon in white wine. Next it's chicken thighs with Asian stuffing and a sticky teriyaki glaze followed by Hasselback potatoes; cherry tomato and roasted garlic soup; and a Kinky Eton mess served with basil oil. D 8:00 am Taste of History"Bartram's Gardens: A Revolution In Gardening" The Philadelphia gardens of botanists John and William Bartram were a favorite excursion for our founding fathers, including Ben Franklin. In this episode, learn how Franklin introduced tofu to America and watch Chef Walter cook Fried Lafayette Fish, Curried Tofu with Shrimp, Turbot and Braised Romaine, in the hearth of Bartram's kitchen. D 8:30 am Simply Ming"Wakiya - Ramen" Nothing says Japan like Ramen noodles - this episode of Simply Ming brings Chef Ming Tsai on the road to the Instant Ramen Museum in Osaka, Japan. Ming also learns the secrets of cooking Ramen from famous Japanese Chef Yuji Wakiya. D 9:00 am The Jazzy Vegetarian"Good Morning Fiesta" Host Laura Theodore prepares a zesty breakfast menu featuring "Tofu Ranchero," a slightly spicy dish served with fresh tomato sauce. For a baked treat, "Cornbread and Sweet Pepper Mini-Muffins" wakes up sleepy taste buds, while "Pineapple, Banana and Strawberry Smoothie" presents a frosty and fruity beverage to get the morning started on an energizing note. D 9:30 am Chef's Life"The World Is Your Oyster" Vivian goes to Cedar Island to explore the new culture of farm-raised oysters in the Southeast. She and Ben share plans of opening an oyster bar across the street from Chef & the Farmer in hopes it will be a place that adds character and variety to the tiny town's "dining scene." Vivian and her dad orchestrate their family's first-ever oyster roast and are blown away by how much everyone enjoys it. D 10:00 am Austin City Limits"Sarah Jarosz/The Milk Carton Kids" Showcasing new acoustic music, multi-instrumentalist Jarosz highlights her album Build Me Up From Bones. Then the Milk Carton Kids play folk songs from their album The Ash & Clay.G Dinosaur Train"That's Not A Dinosaur/Tiny's Garden" The kids visit the Big Pond to attend the Biome Block Party. While attempting to win the leaf-necklace contest, Keenan Chirostemotes claims the Pteranodon sibs can't compete for the prize for "dinosaur" with the most leaves because they are not dinosaurs. This launches the kids into a song called "That's Not a Dinosaur", as all the non-dinosaurs sing their piece. D 12:30 pm Peg + Cat"The Slop Problem/The Birthday Present Problem" The Slop Problem - The Farm. Peg and Cat enlist the Teens to help them figure out how to clean filthy farm animals of various sizes. Primary Content: More, less; Secondary Content: Counting by fives up to 25. D 1:00 pm Cat in the Hat Knows A Lot About That!"Flutter By Butterfly/Pretty In Pink" Flutter By Butterfly - Sally and Nick are pretending to be butterflies, but they're not very good at it. The Cat takes them to meet Bernadette the Monarch butterfly, who can teach them all about fluttering. Following Bernadette from Milky Weed Meadow to Prickly Pines forest they learn that butterfly wings are used for so much more than just fluttering! Pretty in Pink - Sally and Nick are having fun trying out different moves when the Cat arrives to show them some cool moves of his own. D 1:30 pm WordGirl"Two Brains Forgets/Banned on the Run" Two Brains Forgets - It looks like all is lost when Dr 2-Brains discovers WordGirl's secret identity! But some quick thinking, some help from the Botsford family, and a little luck save the day when 2-Brains' amnesia ray ends up working on the Doc himself. Banned on the Run - Mr. Big finally cheats his way to becoming the town Mayor - and his first order of business is to ban Word Girl! WG and Huggy must restore order to the town and undo all of the silly laws Mr Big keeps passing. D 2:00 pm The Mind of a Chef"Gluttony" It's gluttonous goodness in this episode - over-the-top indulgence with Joe Beef chefs Federic Morin and David McMillian's foie gras sandwich, a whiskey tasting mayhem with Chef Sean Brock at Buffalo Trace in Kentucky and the classic dish "Hot Brown" served up three ways. D 2:30 pm Rick Steves' Europe"North Wales: Feisty and Poetic" Rick takes in Mount Snowdon, medieval castles and Victorian promenades. He learns a bit of Welsh, follows a miner deep into a slate mine, and herds sheep with a clever dog.G The Red Green Show"Homemade Cheese" Junior's house develops a major mouse infestation. On Handyman Corner, Red offers pest control tips while Bill demonstrates his skill at cheesemaking.G 7:30 pm Hebburn"Dressing Up Fancy" Hebburn lays down the red carpet for Sarah's parents, Ben and Susan from York, who are visiting the Pearson home for the first time. They get costuming help from Vicky and Denise to attend the fancy dress competition at Swayze's pub in town. But when the competition turns to violence, an unlikely hero is born.G 8:00 pm May to December"The Way You Look Tonight" Zoe feels inadequate when Simone boasts of how domesticated her mother was. Hillary is still infatuated with Anthony, while Vera ponders how to put her off the scent.G 8:30 pm My Family"Harpers & Queen (New Year's Special)" Ben is dressed for an expected New Year's trip to Mauritius, courtesy of Susan. But Susan gets a notice that she is on the New Year's list for MBE honors, Most Excellent Order of the British Empire, placing her among the junior levels of British orders of chivalry. Not wanting to miss the investiture of even a junior level, Susan commands that Ben attend the ceremony, leading to a sticky result.G 9:00 pm My Hero"Zero Tolerance" George collars a robber at the health clinic without superpowers and is invited by Janet's father to join Neighborhood Watch.G 9:30 pm Last of the Summer Wine"Bushes at Dawn" Foggy and Clegg band together to help their friend Compo who discovers Nora with another man.G 10:00 pm As Time Goes By"Branching Out" Jean is opening another secretarial agency and looking for someone to run it. Meanwhile, work for Lionel seems to have dried up.G The Red Green Show"Homemade Cheese" Junior's house develops a major mouse infestation. On Handyman Corner, Red offers pest control tips while Bill demonstrates his skill at cheesemaking.G 11:30 pm Hebburn"Dressing Up Fancy" Hebburn lays down the red carpet for Sarah's parents, Ben and Susan from York, who are visiting the Pearson home for the first time. They get costuming help from Vicky and Denise to attend the fancy dress competition at Swayze's pub in town. But when the competition turns to violence, an unlikely hero is born.GMast cell-nerve interaction in the colon of Trypanosoma cruzi-infected individuals with chagasic megacolon. Chagas disease is an infection caused by the parasite Trypanosoma cruzi that affects millions of people worldwide and is endemic in Latin America. Megacolon is the most frequent complication of the digestive chronic form and happens due to lesions of the enteric nervous system. The neuronal lesions seem to initiate in the acute phase and persist during the chronic phase, albeit the mechanisms involved in this process are still debated. Among the cells of the immune system possibly involved in this pathological process is the mast cell (MC) due to its well-known role in the bi-directional communication between the immune and nervous systems. Using ultrastructural analysis, we found an increased number of degranulated MCs in close proximity to nerve fibers in infected patients when compared with uninfected controls. We also immunostained MCs for the two
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20734, 13, 285, 342, 14896, 275, 2800, 273, 521, 1390, 4314, 24662, 13, 247, 1943, 3330, 689, 330, 1000, 531, 476, 1691, 779, 275, 253, 7827, 323, 247, 1533, 4060, 5103, 387, 20029, 12511, 15, 1244, 326, 457, 84, 10534, 2139, 344, 2335, 253, 3819, 15, 187 ]	She does recall asking in her freshman year why the football team was allowed to arrive on campus before classes, “but then the field hockey team was allowed to arrive early by my sophomore year.” And while fundraising was a background theme at the June event, attendees did buzz about the ongoing Garcelon Field project to install a FieldTurf surface plus new grandstands, lights, and press box. The $2.6 million project, as a matter of fact, is entirely donor-funded. Bestest Behavior Newly created this year, Bates Best awards recognize significant work by alumni and parents that engages Bates people with the College and that displays passion and commitment for advancing the Bates mission. The Bates Best awards presented at the Volunteer Recognition Dinner in May honored volunteer work during 2009–10, while at the Athletics Celebration, Bates Best awards recognized lasting contributions to the Bates athletics program.package commands type CreatePrivateDomainsCommand struct { BaseCFConfigCommand BasePeekCommand } //Execute - creates private domains func (c CreatePrivateDomainsCommand) Execute([]string) error { var cfMgmt CFMgmt var err error if cfMgmt, err = InitializePeekManagers(c.BaseCFConfigCommand, c.Peek); err == nil { err = cfMgmt.PrivateDomainManager.CreatePrivateDomains() } return err } China, euro zone sovereign debt and the potential fallout from Brexit top the escalating list of concerns for the Bank of England (BOE), according to a report published on Wednesday which warns that risks to global stability have spiked in the past six months. The U.K.'s central bank's semi-annual Financial Stability Report states, "Vulnerabilities stemming from the global environment and financial markets, which were already elevated, have increased further since July." Red flag over China Chris Ratcliffe \| Bloomberg \| Getty Images China's burgeoning debt levels and rapid rate of credit expansion are singled out as significant red flags, with the report noting a 100 percentage point spike in the country's non-financial sector debt relative to gross domestic product (GDP) since the 2008 financial crisis. The ratio currently stands at around 260 percent of GDP. "This is extraordinary leverage for an advanced, let alone, an emerging economy," the BOE Governor Mark Carney said at a press conference to launch the report. The "near-record" pace of net capital outflows from China during the third quarter and a 3 percent depreciation in the Chinese renminbi against the U.S. dollar since the publication of the BOE's July report were also highlighted as reasons for concern. Euro area dynamics Turning to nearer neighbors, the governor broke down the key risks emanating from some euro area economies into, firstly, existing sovereign debt dynamics and, secondly, threats to the resilience of parts of the trading bloc's banking system. Carney noted the vulnerability of elevated sovereign debt levels to a leap in borrowing costs or diminished growth prospects on the back of either trade or political headwinds. Moving even closer to home, the governor raised the looming specter of the U.K.'s impending departure from the European Union (EU), noting banks located domestically currently supply over half of the debt and equity issuance from continental firms and account for over 75 percent of foreign exchange and derivatives activity in the U.K. Consequent fears of contagion were emphasized by Carney as he discussed the risk of a disruption in services provided to the European real economy spilling over to hit the U.K. economy through trade and financial links. While clearly stating that the largest risks to U.K.financial stability are global in nature, the governor went on to acknowledge that a lack of clarity over how Brexit will unfold means many unknowns cloud the current outlook. "It will take time to clarify the U.K.'s new relationships with the EU and the rest of the world. And the orderliness of the U.K. economy's adjustment to these changes will influence the risks to financial stability," Carney said.Q: Enviar funcion con parametros JavaScript Tengo la siguiente linea de codigo: <td border="1" onClick="myFunction()"> Estoy tratando de hacer lo siguiente para poder recibir un valor en la funcion myFunction(variable). <td border="1" onClick="myFunction(variable)"> Pero me envia el siguiente error: is not defined at HTMLTableCellElement.onclick A: Lo que quieres hacer va de la siguiente forma: function myFunction(mensaje) { console.log(mensaje); } table, th, td { border: 1px solid black; } <table> <tr> <td onClick="myFunction('Celda A')">Celda A</td> <td onClick="myFunction('Celda B')">Celda B</td> </tr> </table> Nota: Si quieres enviar algún tipo de variable y te da error, deberás poner mas código en tu pregunta. Melvin Guillard - A Fighting Education When it was announced that Melvin Guillard was going to fight Donald Cerrone at UFC 150 this Saturday, just a little over a month after going three rounds against Fabricio Camoes, many wondered how “The Young Assassin” would react to such a short turnaround time. Short? Guillard considers two fights in a month a vacation compared to his early days in the sport. “I’m a fighter and I love to fight,” he said. “Growing up, when I first started fighting, fighting two, three times, and sometimes six times in one month was normal for me. So fighting this close back-to-back kind of brings back memories of my younger days.” He’s not kidding when he says younger days. Still more than seven months away from his 30th birthday, the New Orleans native has been fighting in one way, shape, or form since he was 14, first as an amateur before turning pro at 16. “I’ve been at it for a long time,” he laughs as he delivers the understatement of the summer. “And even when I turned 16 and turned pro, it was about grinding, and just fighting to make a paycheck. Back then I was making five and five, which was 500 and 500, a thousand and a thousand, and I was living off that money. That was part of the reason why I chose to fight so much at that time.” But in an odd way, fighting Guillard wasn’t just something he was good at; it was a way for him to bond with his father, who passed away in 2006, in a different way than most teens and their dads. “My dad went to every fight, he signed my pro license, and me and my dad were like best friends, so we got to hang out all the time,” said Guillard. “He would go to the bars, watch me fight, take me home, and I even had one of my wrestling buddies, Terry Verdun, he would fight on Friday nights with me. We would go and fight together and just beat people up. That was my hangout, and that was the thing that I was doing because I was hanging out with my high school friend and my dad. Then it blew up so big at home for me to where everybody from home would come and watch me fight. So then I would make money from selling tickets in the neighborhood, and I would have my whole neighborhood coming out once or twice a month to watch me fight and be the main event at the club called Main Event.” Guillard would pile up win after win, and knockout after knockout, some sanctioned by the local commission, some not. It was a heady time for the aspiring UFC fighter, even if he didn’t know at the time whether the UFC was going to be the worldwide juggernaut it is today. The adults around him at school were even less optimistic. “Fighting in the UFC was always my childhood dream and I knew back then that they didn’t make a whole lot of money doing it, but somewhere in there, I thought to myself that this sport might just blow up and take off and it could be big, and I was right,” he said. “I even had schoolteachers and principals, people that were elders to me and mentors that I looked up to, telling me that I was crazy for trying to be an MMA fighter. They thought it was violent and brutal, that guys always got hurt and didn’t make any money, and now those same people are looking at me like ‘kid, you must have known something we didn’t know at the time.’ So it’s definitely refreshing and cool to know that I chose something that other people actually doubted, and I was right about it.” Nearly 14 years after the first time he put the gloves on and got paid for it, Guillard is co-headlining a major UFC event in Denver, and with wins in six of his last eight fights, a big win over Cerrone can put him in the conversation for a world title shot at 155 pounds. And that’s precisely why he took the fight.
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41951, 313, 27767, 58, 28, 8444, 7121, 31497, 13, 3690, 904, 48922, 13, 11248, 13, 5106, 10, 497, 49238, 342, 44280, 310, 41365, 49219, 313, 22, 6, 275, 473, 95, 19, 13611, 285, 39875, 1025, 407, 385, 84, 2435, 1515, 15, 23077, 23220, 35688, 369, 7011, 13, 22269, 273, 40457, 4408, 13, 2624, 715, 495, 1186 ]	was dripped directly onto the heart as needed for arrhythmia control during ischemia, and procainamide (12.5 mg/kg IP) was administered 15 min prior to reperfusion. Rats were orally gavaged with vehicle (0.5% HPMC, 5% DMSO, and 0.1% Tween 80; 10 mL/kg; n = 14), GSK2181236A (0.1 or 1.0 mg/kg; n = 11--14), or BAY 60-4552 (0.3 or 3.0 mg/kg; n = 10--12) 2 h prior to ischemia. Blood was collected at the initiation of ischemia and after 24 h reperfusion. Plasma was obtained for analysis of compound concentrations and levels of cardiac Troponin I (cTnI), a circulating biomarker of cardiac injury. Plasma concentrations of cTnI were determined using a commercially available ELISA (catalog \#2010-2-HSP, Life Diagnostics, West Chester, PA, USA) according to the manufacturer's instructions. Plasma compound concentrations were determined by LC/MS/MS (API 5000 triple quadrupole mass spectrometer, ABSciex, Foster City, CA, USA; Prominence liquid chromatographic system, Shimadzu, Columbia, MD, USA). Rats were anesthetized with a mixture of ketamine and xylazine (35 and 5 mg/kg, IM) and euthanized via exsanguination. Hearts were excised and perfused with 1% Evans blue dye in saline then perfused-fixed with 10% neutral buffered formalin (∼90 mmHg perfusion pressure). Hearts were sliced on the short axis from apex to base at 1--2 mm intervals, and the ischemic area (area at risk) was evaluated using Image Pro-Plus (Media Cybernetics, Inc., Bethesda, MD, USA). Fresh heart slices were stained with 1% triphenyltetrazolium and evaluated using Image Pro-Plus for determination of infarct size. Cardiac and renal function assessment of GSK2181236A and BAY 60-4552 in HSFD fed SHR-SP --------------------------------------------------------------------------------------- The SHR-SP is an established model of genetic hypertension. Exposure to a HSFD exacerbates endothelial dysfunction, systemic vascular resistance and hypertension, and accelerates end-organ damage (Ma et al., [@B21]). Decreases in endothelium-dependent vasorelaxation in this model have been associated with reduced levels of NO bioactivity and increased generation of superoxide and/or peroxynitrite anions (McIntyre et al., [@B23], [@B22]; Kerr et al., [@B15]; Ma et al., [@B21]; see Bauersachs and Widder, [@B2] for review). As such, a cohort of HSFD SHR-SP was established as a model of cardiovascular disease associated with chronic oxidative stress in this study. Male SHR-SPs (n = 75) were obtained from Charles River Laboratories, Inc. (Kingston, NY, USA) and maintained on a normal powdered rodent diet (Lab Diet 5001, PMI Nutrition International, LLC, St. Louis, MO, USA) and tap water ad libitum. A subgroup of animals (n = 45) was anesthetized with isoflurane and surgically implanted with radiotelemetry transmitters (PhysioTel PA-C40, Data Sciences International, St. Paul, MN, USA). The transmitter catheter was threaded through the femoral artery into the abdominal aorta. At 11--12 weeks of age, baseline blood pressure and heart rate were measured for 5 days (10 s recordings every 5 min) in normal caging, then rats were acclimated to metabolic caging for a minimum of 48 h before a basal 24 h urine sample and blood were collected. After baseline measures, rats were assigned to six groups (n = 8--14 per group) according to mean arterial pressure (MAP; telemetered rats only) and body weight: normal diet (ND) control, HSFD, HSFD + 0.1 mg/kg/day GSK2181236A, HSFD + 1.0 mg/kg/day GSK2181236A, HSFD + 0.3 mg/kg/day BAY 60-4552, and HSFD + 3.0 mg/kg/day BAY 60-4552. The ND group was maintained on normal chow and water throughout the study. The other groups received a fat-enriched rodent diet (24.5% fat, Zeigler Bros., Inc., Gardners, PA, USA) and a 1% NaCl drinking water solution ad libitum for 8 week (Willette et al., [@B35]). Rats displaying signs of morbidity which included piloerection, lack of grooming, persistent body weight loss, lethargy, or seizure/convulsions, were promptly euthanized. Treatments were administered in respective diets starting 1 week after the initiation of HSFD. Urine collections were repeated on weeks 2, 4, 6, and 8 and blood was sampled in the morning after each 24 h collection period for assessment of renal function. Plasma creatinine and urine sodium, microalbumin (MALB), and creatinine were ascertained using an AU640 Chemistry Analyzer (Olympus America, Inc., Center Valley, PA, USA). Plasma compound concentrations were determined as described above. During week 7, cardiac function and morphometry were evaluated via transthoracic echocardiography. Rats were anesthetized with isoflurane (2--4% induction and 1--3% maintenance). Two-dimensional gray scale images of the left ventricle were obtained in the short axis plane at mid-ventricle level and in the parasternal long axis plane using a GE Vivid 7 system (GE Medical Systems, Milwaukee, WI, USA) and stored as digital cineloops. Pulse wave Doppler recordings from the LV outflow were obtained to determine heart rate. All images were analyzed by a single observer using a GE EchoPac (GE Medical Systems, Milwaukee, WI, USA). LV volumes were calculated as $V = \frac{5}{6}(\text{LVA} \times \text{LVL)}$ where LVA is area of LV chamber from the short axis view and LVL is the LV length from the long axis view at end diastole and end systole. LV mass was calculated from two dimensional images using the area-length method (Lang et al., [@B19]). Analysis was performed on three to five cardiac cycles. On week 8, isoflurane anesthetized rats were euthanized via exsanguination. The thoracic aorta was excised for assessment of endothelial function as described below. Hearts were snap-frozen in liquid nitrogen and stored at −80°C for later analysis of gene expression changes associated with cardiac hypertrophy and fibrosis (see below for procedure details). Gene expression analysis of cardiac tissue ------------------------------------------ Cardiac gene expression was analyzed following chronic (7 week) BAY 60-4552 or GSK2181236A treatment in HSFD SHR-SP. Hearts were homogenized in Trizol and RNA was extracted using the RNeasy Plus Mini kit protocol (Qiagen, Valencia, CA, USA) with a 40 μL elution volume. RNA was quantified using a Nanodrop Spectrophotometer ND-1000 (Thermo Fisher Scientific, Wilmington, DE, USA) and converted to cDNA using the High Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Carlsbad, CA, USA). Taqman assays were performed using a 384-well plate format with individual primer-probes and Taqman Universal PCR Master Mix (Applied Biosystems) and run on the 7900 HT Fast Real-Time PCR System (Applied Biosystems). SDS 2.3 software (Applied Biosystems) was used to obtain raw C~t~ values with manual threshold set at 0.10. Array Studio software (version 3.6.2; OmicSoft Corporation, Cary, NC, USA) was used to normalize gene expression data, by analysis of covariance, to the housekeeper genes β-2-microglobulin (B2m) and peptidyl-prolyl cis-trans isomerase A (Ppia). No outliers were detected by means of principal component analysis. The following genes were analyzed: α-skeletal actin (Acta1), type 1 collagen-alpha 1 (Col1a1), type 3 collagen-alpha 1 (Col3a1), connective tissue growth factor (CTGF; Ctgf), matrix metalloproteinase 2 (MMP2; Mmp2), matrix metalloproteinase 9 (MMP9; Mmp9), α-myosin heavy chain (α-MHC; Myh6), β-myosin heavy chain (β-MHC; Myh7); atrial natriuretic factor (ANF; Nppa), brain-type natriuretic peptide (BNP; Nppb), cGMP-specific phosphodiesterase 5A (PDE5A; Pde5a), type 2 cGMP-dependent protein kinase (PKG2; Prkg2), and transforming growth factor beta 1 (TGF-β1; Tgfb1). Isolated artery vasodilatation ------------------------------ Male Wistar Kyoto (WKY; Charles River Laboratories, Inc., Raleigh, NC, USA) were anesthetized with inhaled isoflurane (5% in O~2~) and euthanized by exsanguination. Thoracic aorta was isolated, cleaned of adherent tissue, cut into 3
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Since $u\gamma$ and $v\gamma$ are computable by induction hypothesis, $s\gamma=@(u\gamma,v\gamma)$ is computable by computability property (iv). 3. $s=\lambda x . u$. By computability property (v), $s\gamma=\lambda x.u\gamma$ is computable iff $u\gamma\{x\mapsto v\}$ is computable for an arbitrary computable $v$. Let now $\gamma'=\gamma\cup\{x\mapsto v\}$. By definition of substitutions for abstractions, $u\gamma\{x\mapsto v\}=u\gamma'$, which is usually ensured by $\alpha$-conversion. By assumptions on $\gamma$ and $v$, $\gamma'$ is computable, and $u\gamma'$ is therefore computable by the main induction hypothesis. Since an arbitrary term $s$ can be seen as its own instance by the identity substitution, which is computable by computability property (iii), all terms are computable by the Main Lemma, hence strongly normalizing by computability property (i). The Recursive Path Ordering and Computability {#s:rpo} ============================================= In this section, we restrict ourselves to first-order algebraic terms. Assuming that the set of function symbols is equipped with an ordering relation $\geF$, called precedence, and a status function $stat$, writing $stat_f$ for $stat(f)$, we recall the definition of the recursive path ordering: \[d:rpo\] $s\gtrpo t$ iff 1. \[rposubt\] $s=f(\vect{s})$ with $f\in\F$, and $ u \displaystyle{\gerpo} t$ for some $u\in\vect{s}$ 2. \[rpoprec\] $s=f(\vect{s})$ with $f\in\F$, and $t=g(\vect{t})$ with $f\gtF g$, and $A$ 3. \[rpomul\] $s=f(\vect{s})$ and $t=g(\vect{t})$ with $f=_\F g\in\Mul$, and $\vect{s}~(\displaystyle{\gtrpo})_{mul}~ \vect{t}$ 4. \[rpolex\] $s=f(\vect{s})$ and $t=g(\vect{t})$ with $f=_\F g\in\Lex$, and $\vect{s}~(\displaystyle{\gtrpo})_{lex}~ \vect{t}$ and $A$ $$\mbox{where } A=\forall v\in\vect{t}. ~ s\gtrpo v \quad\mbox{ and }\quad s\gerpo t \mbox{ iff } s\gtrpo t \mbox{ or } s=t$$ We now show the well-foundedness of $\gtrpo$ by using Tait’s method. Computability is defined here as strong normalization, implying computability property (i). We prove the computability property: \(vii) Let $f\in\F_n$ and $\vect{s}$ be computable terms. Then $f(\vect{s})$ is computable. The restriction of $\succ_{rpo}$ to terms smaller than or equal to the terms in $\vect{s}$ w.r.t. $\succ_{rpo}$ is a well-founded ordering which we use for building an outer induction on the pairs $(f,\vect{s})$ ordered by $(>_\F, (\succ_{rpo})_{stat_f})_{lex}$. This ordering is well-founded, since it is built from well-founded orderings by using mappings that preserve well-founded orderings. We now show that $f(\vect{s})$ is computable by proving that $t$ is computable for all $t$ such that $f(\vect{s}) \succ_{rpo} t$. This property is itself proved by an (inner) induction on $\|t\|$, and by case analysis upon the proof that $f(\vect{s}) \succ_{rpo} t$. 1. subterm case: $\exists u\in\vect{s}$ such that $u \succ_{rpo} t$. By assumption, $u$ is computable, hence so is its reduct $t$. 2. precedence case: $t=g(\vect{t})$, $f>_\F g$, and $\forall v\in\vect{t}$, $s\succ_{rpo} v$. By inner induction, $v$ is computable, hence so is $\vect{t}$. By outer induction, $g(\vect{t})=t$ is computable. 3. multiset case: $t=f(\vect{t})$ with $f\in Mul$, and $\vect{s}(\succ_{rpo})_{mul} \vect{t}$. By definition of the multiset extension, $\forall v\in\vect{t},~\exists u\in\vect{s}$ such that $u\succeq_{rpo} v$. Since $\vect{s}$ is a vector of computable terms by assumption, so is $\vect{t}$. We conclude by outer induction that $f(\vect{t})=t$ is computable. 4. lexicographic case: $t=f(\vect{t})$ with $f\in Lex$, $\vect{s}(\succ_{rpo})_{lex} \vect{t}$, and $\forall v\in\vect{t},~s\succ_{rpo} v$. By inner induction, $\vect{t}$ is strongly normalizing, and by outer induction, so is $f(\vect{t})=t$. The well-foundedness of $\gtrpo$ follows from computability property (vii). The General Schema and Computability {#s:closure} ==================================== As in the previous section, we assume that the set of function symbols is equipped with a precedence relation $\geF$ and a status function $stat$. \[d:closure\] The computability closure $\CS(t=f(\vect{t}))$, with $f\!\in\!\F$, is the set $\CS(t,\emptyset)$, s.t. $\CS(t,{\cal V})$, with ${\cal V}\cap\Var{t}=\emptyset$, is the smallest set of typable terms containing all variables in ${\cal V}$ and terms in $\vect{t}$, closed under: 1. \[csubterm\] subterm of basic type: let $s\in\CS(t,{\cal V})$, and $u$ be a subterm of $s$ of basic type $\sigma$ such that $\Var{u}\subseteq \Var{t}$; then $u\in\CS(t,{\cal V})$; 2. \[cprecedence\] precedence: let $f\gtF g$, and $\vect{s}\in\CS(t,{\cal V})$; then $g(\vect{s})\in\CS(t,{\cal V})$; 3. \[crecursive\] recursive call: let $f(\vect{s})$ be a term such that terms in $\vect{s}$ belong to $\CS(t,{\cal V})$ and $\vect{t} (\lrps{}{\beta}\cup\gtsubt)_{stat_f} \vect{s}$; then $g(\vect{s})\in\CS(t,{\cal V})$ for every $g =_\F f$; 4. \[capplication\] application: let $s : \sigma_1\ra\ldots\ra\sigma_n\ra\sigma\in\CS(t,{\cal V})$ and $u_i:\sigma_i \in\CS(t,{\cal V})$ for every $i\in[1..n]$; then $@(s,u_1,\ldots,u_n)\in\CS(t,{\cal V})$; 5. \[cabstraction\] abstraction: let $s\in\CS(t,{\cal V}\cup\{x\})$ for some $x\notin\Var{t}\cup{\cal V}$; then $\lambda x . s \in\CS(t,{\cal V})$; 6. \[creduction\] reduction: let $u \in \CS(t,{\cal V})$, and $u\lrps{}{\beta\cup\gtsubt} v$; then $v\in \CS(t,{\cal V})$. We say that a rewrite system $R$ satisfies the general schema iff $$\mbox{$r\in\CS(f(\vect{l}))$ for all $f(\vect{l})\ra r\in R$}$$ We now consider computability with respect to the rewrite relation $\lrps{}{R}\cup\lrps{}{\beta}$, and add the computability property (vii) whose proof can be easily adapted from the previous one. We can then add a new case in Tait’s Main Lemma, for terms headed by an algebraic function symbol. As a
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27, 2417, 187, 10619, 346, 510, 3295, 6222, 273, 634, 313, 21423, 10, 5724, 449, 187, 10653, 4890, 187, 187, 10326, 28222, 4658, 72, 11548, 5397, 16 ]	ctxt "text-direction" msgid "From left to right" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1788 msgctxt "text-direction" msgid "From right to left" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1789 msgctxt "text-direction" msgid "Vertical, right to left (mixed orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1790 msgctxt "text-direction" msgid "Vertical, right to left (upright orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1791 msgctxt "text-direction" msgid "Vertical, left to right (mixed orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1792 msgctxt "text-direction" msgid "Vertical, left to right (upright orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1823 #, fuzzy msgctxt "text-hint-style" msgid "None" msgstr "קײנע" #: ../libgimpbase/gimpbaseenums.c:1824 msgctxt "text-hint-style" msgid "Slight" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1825 msgctxt "text-hint-style" msgid "Medium" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1826 msgctxt "text-hint-style" msgid "Full" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1857 msgctxt "text-justification" msgid "Left justified" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1858 msgctxt "text-justification" msgid "Right justified" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1859 msgctxt "text-justification" msgid "Centered" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1860 msgctxt "text-justification" msgid "Filled" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1890 msgctxt "transfer-mode" msgid "Shadows" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1891 msgctxt "transfer-mode" msgid "Midtones" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1892 msgctxt "transfer-mode" msgid "Highlights" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1921 msgctxt "transform-direction" msgid "Normal (Forward)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1922 msgctxt "transform-direction" msgid "Corrective (Backward)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1953 msgctxt "transform-resize" msgid "Adjust" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1954 msgctxt "transform-resize" msgid "Clip" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1955 msgctxt "transform-resize" msgid "Crop to result" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1956 msgctxt "transform-resize" msgid "Crop with aspect" msgstr "" #: ../libgimpbase/gimpmetadata.c:951 #, c-format msgid "Can load metadata only from local files" msgstr "" #: ../libgimpbase/gimpmetadata.c:965 ../libgimpbase/gimpmetadata.c:1035 #, c-format msgid "Conversion of the filename to system codepage failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1022 #, c-format msgid "Can save metadata only to local files" msgstr "" #: ../libgimpbase/gimpmetadata.c:1084 #, c-format msgid "Invalid Exif data size." msgstr "" #: ../libgimpbase/gimpmetadata.c:1113 #, c-format msgid "Parsing Exif data failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1163 #, c-format msgid "Parsing IPTC data failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1211 #, c-format msgid "Parsing XMP data failed." msgstr "" #: ../libgimpbase/gimputils.c:219 ../libgimpbase/gimputils.c:224 msgid "(invalid UTF-8 string)" msgstr "" #: ../libgimpbase/gimputils.c:394 msgid "File path is NULL" msgstr "" #: ../libgimpbase/gimputils.c:403 ../libgimpbase/gimputils.c:414 msgid "Error converting UTF-8 filename to wide char" msgstr "" #: ../libgimpbase/gimputils.c:422 msgid "ILCreateFromPath() failed" msgstr "" #: ../libgimpbase/gimputils.c:459 #, c-format msgid "Cannot convert '%s' into a valid NSURL." msgstr "" #: ../libgimpbase/gimputils.c:487 msgid "Connecting to org.freedesktop.FileManager1 failed: " msgstr "" #: ../libgimpbase/gimputils.c:511 msgid "Calling ShowItems failed: " msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:258 #, c-format msgid "'%s' does not appear to be an ICC color profile" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:304 msgid "Data does not appear to be an ICC color profile" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:361 msgid "Could not save color profile to memory" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:578 msgid "(unnamed profile)" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:620 #, c-format msgid "Model: %s" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:629 #, c-format msgid "Manufacturer: %s" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:638 #, c-format msgid "Copyright: %s" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:24 msgctxt "color-management-mode" msgid "No color management" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:25 msgctxt "color-management-mode" msgid "Color-managed display" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:26 msgctxt "color-management-mode" msgid "Soft-proofing" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:57 msgctxt "color-rendering-intent" msgid "Perceptual" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:58 msgctxt "color-rendering-intent" msgid "Relative colorimetric" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:59 msgctxt "color-rendering-intent" msgid "Saturation" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:60 msgctxt "color-rendering-intent" msgid "Absolute colorimetric" msgstr "" #. * #. * SECTION: gimpcolorconfig #. * @title: GimpColorConfig #. * @short_description: Color management settings. #. * #. * Color management settings. #. * #: ../libgimpconfig/gimpcolorconfig.c:52 msgid "How images are displayed on screen." msgstr "" #: ../libgimpconfig/gimpcolorconfig.c:55 msgid "The color profile of your (primary) monitor." msgstr "" #: ../libgimpconfig/
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14, 48791, 313, 4883, 10, 4324, 403, 1929, 281, 40195, 7601, 4324, 2424, 323, 35229, 9953, 390, 2380, 9130, 2393, 275, 5066, 1254, 35, 1166, 14, 13101, 14, 2904, 14, 11494, 1166, 29547, 824, 2425, 4419, 253, 4702, 273, 247, 6640, 14, 12534, 9579, 800, 2570, 327, 253, 22116, 275, 247, 13227, 33636, 7601, 5223, 263, 313, 3788, 28259, 4587, 6820, 5133, 1254, 35, 1166, 14, 13101, 14, 2904, 14, 11494, 1166, 1656, 733, 3133, 2590, 326, 253, 3167, 894, 22116, 403, 247, 2234, 2303, 273, 34392, 2250, 13, 5185, 342, 776, 3332, 1304, 48447, 326, 34392, 5066, 14757, 247, 35035, 44461, 273, 22116, 29747, 342, 25047, 13227, 37742, 285, 8655, 26301, 38528, 3275, 275, 329, 25469, 1966, 34011, 13923, 1341, 1254, 35, 746, 14, 13101, 14, 2904, 14, 11494, 1166, 29547, 326, 841, 2538, 327, 22116, 7278, 9907, 19556, 1254, 35, 1166, 14, 13101, 14, 2904, 14, 11494, 1166, 2947, 35, 746, 14, 13101, 14, 2904, 14, 11494, 1166, 1184, 2007, 8525, 253, 2934, 326, 3167, 894, 22116, 403, 247, 2234, 2303, 273, 34392, 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1254, 35, 746, 14, 13101, 14, 2904, 14, 11494, 1166, 1184, 285, 2708, 481, 187, 187, 510, 1263, 1060, 4648, 36225, 19630, 53, 1341, 16, 19395, 13335, 10445, 347, 253, 18023, 1566, 281, 5100, 253, 2234, 2554, 273, 24154, 309, 275, 253, 3486, 273, 34392, 5066, 327, 13227, 1159, 15, 844, 921, 326, 34392, 5066, 7052, 16274, 13227, 11900, 1159, 13, 4283, 281, 10702, 26301, 38528, 3275, 13, 285, 326, 253, 26301, 38528, 660, 7603, 1063, 13, 353, 7067, 50, 13, 275, 8493, 26301, 38528, 275, 9813, 1341, 13, 476, 1421, 281, 3777, 34392, 14970, 285, 6581, 3275, 15, 831, 8495, 84, 9670, 342, 776, 2045, 1263, 1254, 35, 746, 14, 13101, 14, 2904, 14, 11494, 1166, 5413, 970, 625, 13424, 3210, 273, 34392, 5066, 13, 1690, 329, 25469, 1966, 34011, 13923, 1341, 285, 3625, 1966, 13605, 4635, 6062, 13923, 1341, 13, 835, 34392, 5066, 7052, 1305, 16443, 13227, 11900, 1159, 285, 6478, 684, 26301, 38528, 2308, 13, 534, 476, 320, 14415, 342, 353, 7067, 50, 15, 844, 671, 921, 326, 353, 7067, 50, 24696, 1411, 34392, 1060, 13, 1014, 672, 2879, 3387, 288, 1501, 14, 30295, 2470, 2841, 721, 1084, 13101, 14, 2904, 14, 11494, 1166, 14, 71, 7174, 910, 709, 14, 881, 568, 926, 9471, 27594, 326, 353, 7067, 50, 476, 320, 3576, 275, 8493, 253, 9907, 3301, 13, 1014, 275, 271, 4232, 34392, 5066, 15, 844, 452, 3786 ]	3-cells-08-01417} --------------------------------------------------------------------------------------------------------------------------------------------------------------- The data above clearly implies a causative role for mtROS in facilitating RSV infectious virus production. To test this formally, we decided to test whether blocking mtROS generation during RSV infection could limit RSV infection, as previously done, using the mtROS scavenger MitoQ \[[@B19-cells-08-01417]\]. Wild-type and KO cells were infected with RSV (MOI 1) and then treated with MitoQ at different times p.i., prior to cell lysis and subsequent quantitation of viral replication (qPCR) and infectious virus production (plaque assay) ([Figure 5](#cells-08-01417-f005){ref-type="fig"}). Results were unequivocal, showing significant (p \< 0.001) reduction of both viral replication and infectious virus production in both wild-type and KO cells in the presence of MitoQ. Treatment with MitoQ from 8 h p.i. had essentially the same effect in both lines, leading to \>10- and \>100-fold lower levels of RSV genomes and infectious virus titer, respectively ([Figure 5](#cells-08-01417-f005){ref-type="fig"}A,B). MitoQ treatment from 18 h had a less profound effect, but still significantly (p \< 0.001) reduced RSV genomes and the infectious virus titer by \~2- and almost 100-fold, respectively ([Figure 5](#cells-08-01417-f005){ref-type="fig"}A,B). As already indicated, HEK293T cells are an accepted infectious model for RSV \[[@B26-cells-08-01417],[@B27-cells-08-01417],[@B28-cells-08-01417]\]; our previous work with cells of the A549 human alveolar epithelial line, as well as primary human bronchiolar epithelial cells, indicated clear effects of RSV infection on mitochondrial respiratory activity and mtROS production \[[@B19-cells-08-01417]\], closely paralleling those observed here for HEK293T cells. We were keen to establish the relevance of the results here to other models of infection, such as A549 cells, with respect to protection by MitoQ against infection, over a longer, more physiological course of infection. We infected A549 with RSV for up to 8, 12, 24, and 48 h and added MitoQ for the last 8 h in each case ([Figure 6](#cells-08-01417-f006){ref-type="fig"}). The results show that an 8 h addition of MitoQ is able to significantly (p \< 0.001) suppress RSV replication ([Figure 6](#cells-08-01417-f006){ref-type="fig"}A) and infectious virus production ([Figure 6](#cells-08-01417-f006){ref-type="fig"}B), even at late stages of infection (i.e., 40 h p.i.); strikingly, 8 h treatment with MitoQ 40 h p.i. could still reduce infectious virus production almost 100-fold. To confirm that MitoQ's effects in this context are not through impacting cell viability, we assessed the release of the cytosolic enzyme lactate dehydrogenase (LDH) into the culture medium, indicative of cell death ([Figure A1](#cells-08-01417-f0A1){ref-type="fig"} in [Appendix A](#app2-cells-08-01417){ref-type="app"}). None of the MitoQ concentrations used significantly increased LDH release compared to that of controls in either the absence or presence of RSV infection, confirming that MitoQ is not cytotoxic; this is entirely consistent with other studies \[[@B19-cells-08-01417]\], with toxicity also shown to be absent in animal models and humans \[[@B34-cells-08-01417],[@B35-cells-08-01417],[@B36-cells-08-01417],[@B37-cells-08-01417],[@B38-cells-08-01417]\]. Overall, the results underline the relevance of the results here, with respect to the key role of mitochondrial Complex I in RSV infection to the development of anti-RSV therapies, with MitoQ of great potential as a viable option to treat established RSV infection (see Discussion). 4. Discussion {#sec4-cells-08-01417} ============= This is the first study to use KO cells to establish the importance of mitochondrial complex I in RSV infection. Deficiency of either of the specific complex I proteins, NDUFA10 and NDUFB10, that are integral to electron transport and Complex I assembly \[[@B21-cells-08-01417],[@B39-cells-08-01417],[@B40-cells-08-01417]\] results in elevated mtROS levels, compared to wild type ([Figure 4](#cells-08-01417-f004){ref-type="fig"}), and enhanced virus production ([Figure 3](#cells-08-01417-f003){ref-type="fig"}B). This is in stark contrast to the knock-out of other mitochondrial proteins, such as non-complex I protein TMEM261 or complex I component NDUFB4, which has more peripheral roles in super complex formation \[[@B31-cells-08-01417],[@B32-cells-08-01417],[@B41-cells-08-01417]\]; in these cases, lack of expression does not impact mtROS levels ([Figure 4](#cells-08-01417-f004){ref-type="fig"}), and RSV virus production is essentially normal ([Figure 3](#cells-08-01417-f003){ref-type="fig"}B). It is significant in this context that NDUFB10 deficiency has previously been associated with increased mtROS and compromised mitochondrial respiration \[[@B31-cells-08-01417],[@B42-cells-08-01417]\], while mutations in NDUFA10 have been found in mitochondrial disorders, such as Leigh disease \[[@B41-cells-08-01417],[@B42-cells-08-01417],[@B43-cells-08-01417]\]. Future studies could include studying viral growth kinetics in Complex I KO cells to elucidate the precise mechanism by which reduced mtROS favors RSV virus production. It is known that RSV infection interferes with many key cellular functions, but many of these appear to relate, as in the present study, to host cell mitochondria. Unbiased proteomic studies in RSV-infected cells, for example, reveal a large-scale impact on the abundance of a number of mitochondrial proteins, including complex I proteins, as well as voltage-dependent anion channel proteins, mitochondrial antioxidant enzymes, and the prohibitin subunits that play roles in regulating mitochondrial morphology, distribution, and biogenesis \[[@B44-cells-08-01417],[@B45-cells-08-01417],[@B46-cells-08-01417]\]. RSV's non-structural (NS) proteins are known to degrade signaling proteins required for interferon induction or response pathways early in infection \[[@B17-cells-08-01417]\]; such activity requires the formation of a NS-associated degradative complex on the mitochondria in a mitochondrial antiviral signaling adaptor (MAVS)-dependent manner \[[@B17-cells-08-01417]\]. It seems clear that the host cell mitochondria are a key target of RSV action, consistent with our recent report documenting that RSV infection induces a staged redistribution of mitochondria concomitant with compromised mitochondrial respiration and enhanced mtROS production in A549 human alveolar epithelial cells \[[@B19-cells-08-01417]\]; that these effects on mitochondria enhance viral pathogenesis \[[@B17-cells-08-01417],[@B19-cells-08-01417]\] further supports the idea that host cell mitochondria are a key target of RSV action. Our results here indicate for the first time that mitochondrial Complex I is central to this and the effects on decreased mitochondrial respiration and enhanced mtROS levels in particular \[[@B19-cells-08-01417]\]; that reduced Complex I activity leading to decreased mitochondrial respiration and increased mtROS favors RSV infection implicates Complex I as a key target of RSV in infected cells (see model in [Figure 7](#cells-08-01417-f007){ref-type="fig"}), making Complex I a potential therapeutic target for anti-RSV intervention strategies. Importantly in this context, the mtROS scavenger, MitoQ, can limit RSV infection, even in complex I-deficient cells ([Figure 5](#cells-08-01417-f005){ref-type="fig"}), confirming MitoQ's utility as a viable therapeutic to combat RSV in the future (see also \[[@B19-cells-08-01417]\] and below). The study here uses HEK293T cells/KO derivatives thereof as the infectious model to establish the key role of Complex I in the impact of RSV infection on mitochondrial function. We show that RSV infection strongly impacts mitochondrial respiratory function, leading to elevated mtROS production, and that the mtROS scavenger, MitoQ, in reducing mtROS in infected cells, can lead to reduced RSV replication and virus production. This aligns perfectly with our previous study \[[@B19-cells-08-01417]\], using more physiological models of RSV infection, including A549 human alveolar epithelial cells and primary human bronchiolar epithelial cells, where RSV infection strongly depresses mitochondrial respiratory function and elevates mtROS levels, which can be prevented with MitoQ. We also show that MitoQ protects against RSV here, even when added 40 h post-infection ([Figure 6](#cells-08-01417-f006){ref-type="fig"}), implying that MitoQ can be effective in reducing the viral load, even in an established RSV infection. We have previously
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16216, 513, 12888, 1163, 49, 187, 29, 1432, 2225, 348, 31, 4754, 368, 476, 187, 29, 303, 1288, 7541, 31, 1308, 67, 187, 29, 41, 46924, 31, 29168, 2225, 348, 27, 642, 365, 187, 29, 41, 46924, 31, 835, 651, 253, 794, 275, 326, 320, 32, 187, 29, 1432, 2225, 348, 31, 388, 46924, 27, 858, 368, 755, 271, 4579, 432, 8166, 75, 825, 7004, 368, 281, 32, 9418, 187, 29, 41, 46924, 31, 29168, 2225, 348, 27, 4754, 187, 29, 1432, 2225, 348, 31, 7126, 2391, 187, 11, 29168, 2225, 348, 1904, 626, 9418, 187, 11, 388, 46924, 12830, 253, 3579, 6409, 13, 840, 15, 187, 29, 1432, 2225, 348, 31, 352, 434, 9670, 34557, 13, 309, 1053, 626, 2564, 368, 2509, 253, 4572, 187, 29, 14836, 36795, 31, 246, 2421, 90, 33858, 601, 27, 16790, 1024, 634, 1029, 1255, 187, 29, 1299, 12502, 33858, 601, 31, 270, 69, 36795, 27, 23385, 13, 13103, 187, 29 ]	<bddebian> Sure, give me a minute <bddebian> Shit, is revu down? <tonyyarusso> yes <bddebian> grr <tonyyarusso> grr indeedy <bddebian> Heya Hobbsee <LaserJock> tonyyarusso: dude it's still buiding <tonyyarusso> LaserJock: Ah! nvm me then :) * tonyyarusso falsely assumes all of you cool people have magical machines that build in five minutes or less...or something <bddebian> heh, I wish <Hobbsee> heya bddebian <ajmitch> tonyyarusso: you're funny <tonyyarusso> :) <Hobbsee> tonyyarusso: i wish <Hobbsee> tonyyarusso: although it does help to be able to ssh to fast machines. <tonyyarusso> Hobbsee: yeah <ajmitch> Hobbsee: you mean your laptop still isn't fast enough? <Hobbsee> ajmitch: other machines are faster. shrugs <Hobbsee> ajmitch: it's more the fact that it doesnt have a local mirror. <Hobbsee> ajmitch: so i dont have to wait ages for things to download * ajmitch doesn't have anywhere fast to build <bddebian> Well wtf.. <Hobbsee> ajmitch: aurora's not too bad, either. <ajmitch> faster connectivity than what I have <imbrandon> gah i need to make some more cash this month to get my home "network+mirror" back running <imbrandon> and get of my lazy bum and redo my website <ajmitch> heh <ajmitch> find a real job? :) <imbrandon> :) <Hobbsee> heh :) <Hobbsee> imbrandon: were you coming to boston, btw? <imbrandon> Hobbsee: most likely <Hobbsee> awww <Hobbsee> pity <imbrandon> ? * imbrandon feels loved <ajmitch> haha <imbrandon> :) <imbrandon> trying to get my wife into FL/OSS too <imbrandon> hehe <ajmitch> good luck with that <imbrandon> she actualy is kinda, in that she dosent use anything else but i mean contributing too <Hobbsee> bah. someone has good planning <Hobbsee> the linux thingy on today is when half of the second year comp students have their mandatory tutes. <Hobbsee> when that's a group that htey're targetting <LaserJock> tonyyarusso: argg, I don't think I have time to finish kompozer , it looks good to me <Hobbsee> LaserJock: you suck. <Hobbsee> LaserJock: that is all. <LaserJock> :p <Hobbsee> ajmitch: you suck more. <LaserJock> I'll be back <Hobbsee> hahahahahaha <Hobbsee> coward. <tonyyarusso> heh <tonyyarusso> Well, that's what, a + 1/2 ? <imbrandon> hrm anyone ever made a homebrew computer ? <imbrandon> seems like there is sparce info on it <imbrandon> only from the early 80's <StevenK> What do you mean homebrew? <imbrandon> like 8088 / z80 / 8086 breadboard comp <StevenK> At this point, people seem more concerned with stuffing Pentium III's into z80 boxes <imbrandon> heh , i stuffed a c7 into a c64 box :) <StevenK> c7 <StevenK> Gah <StevenK> c7's don't count. :-P <imbrandon> although a 6502 from a c64 or a apple 1 would be a cool homebrew too <tonyyarusso> bddebian: how's your build coming? <guest22> Hi. Can someone explain why revu.tauware.de is down again? * tonyyarusso is selling a C64-SX <tonyyarusso> guest22: I don't think anyone knows yet. <Hobbsee> tonyyarusso: siretart might be doing the machine change over today <imbrandon> -sx ? <tonyyarusso> Hobbsee: ooh, that would make sense <tonyyarusso> imbrandon: portable <imbrandon> how much ? <StevenK> "Portable" you say <tonyyarusso> imbrandon: http://minneapolis.craigslist.org/sys/406011461.html <imbrandon> c64 were pretty protable anyhow <StevenK> What does protable mean? * StevenK hides <tonyyarusso> Althought the link on the posting seems down :( <tonyyarusso> imbrandon: http://en.wikipedia.org/wiki/Commodore_SX-64 for a pic <imbrandon> ahh craigs list , i love craigs list <imbrandon> tonyyarusso: yea i rember it now <tonyyarusso> The keyboard snaps on as a cover over the monitor on the front of the computer, and the prop leg serves as a carrying handle. <StevenK> 10KGs?! <bddebian> tonyyarusso: I still can't get on REVU <imbrandon> if not more <StevenK> That's not so much portable. <imbrandon> tonyyarusso: i wouldent mind buying it but thats too much of a premium for me, if it dosent sell hit me up <tonyyarusso> bddebian: Nor can anyone else. LaserJock was just working from http://www.tonyyarusso.com/kompozer/ manually. <tonyyarusso> imbrandon: We haven't had a response yet, so you could just make an offer (use the cl link - it's my dad) * StevenK teaches bddebian to read scrollback. <imbrandon> k <imbrandon> i will this evening, i'm lazy and dont wanna open gmail atm heheh <imbrandon> but i got it bookmarked <tonyyarusso> lol, that is lazy <imbrandon> StevenK: and btw the c7 was 1.5GHZ ;) <StevenK> imbrandon: You want to use the SX as a desktop? :-P <imbrandon> hahaha well i do have a c64 2400 baud modem <imbrandon> i used to get on bbs's with * tonyyarusso wonders how much work it would take to get Linux running on it <imbrandon> tonyyarusso: one floppy <imbrandon> there is a c64 linux distro <tonyyarusso> imbrandon: Someone's done that port? <tonyyarusso> sweet <imbrandon> LUnix <tonyyarusso> fun <imbrandon> LNG is an operationg system primarly for the good old Commodore64 home-computer. There also is a native version for the successor Commodore128. Ports to other 6502/6510 driven 8Bit Computers are possible but not yet started. LUnix started in 1993 and reached the internet in 1994. In 1997 LUnix0.1 was rewritten from scratch, the result is LNG. <imbrandon> http://lng.sourceforge.net/ <bddebian> Sorry I'm only half pay attention. I'll check it out in a bit <imbrandon> apple 1's were 6502 proc along with others of the time <ajmitch> Hobbsee: cruelty <Hobbsee> ajmitch: warranted, though. <tonyyarusso> bddebian: a short bit would be best, since we want to close up for NPFU, and this is the last one. <ajmitch> Hobbsee: not at all <Hobbsee> ajmitch: but i cant do interviews :P <ajmitch> yes you can <imbrandon> brb <Hobbsee> ajmitch: nope <Hobbsee> where would the fun in that be? <ajmitch> Hobbsee: did you get an email from laserjock asking you to? :) <Hobbsee> ajmitch: yes <ajmitch> excellent.... * ajmitch didn't :) * Hobbsee hits the forward button, then. <ajmitch> it's perfectly alright, I don't mind you doing the interview <bddebian> tonyyarusso: Building now your highness <tonyyarusso> bddebian: lol, awesome <
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1659, 281, 1691, 436, 1953, 390, 3091, 309, 452, 281, 1691, 352, 281, 209, 187, 3614, 1358, 9742, 28047, 15, 681, 16, 390, 667, 643, 2670, 7939, 281, 8031, 27745, 15, 1292, 667, 5430, 352, 310, 1077, 1774, 323, 479, 281, 871, 253, 3662, 15, 187, 8457, 581, 21205, 1304, 479, 670, 253, 5066, 273, 500, 7267, 14 ]	is hard to categorize in both content and form, and that is a very good thing. One could say Jer3miah is more intimate with things Mormon than more official Mormon productions. For example, inherent in Mormonism is a deep-seated sense of history and a connectedness to past and future generations. The dramatic translation of those concepts within Jer3miah is cliff-hanging events that turn on genealogical information and on strange visitors invoking the ancient Nephite setting of the Book of Mormon. Like the embattled hosts within the more epic portions of the Mormon bible, Jeremiah finds himself facing secret combinations of evil. Yet Jer3miah has a more contemporary vibe than the costume drama Mormon mini-epics based on scripture. This is hosted on Vimeo and YouTube, and it channels the youth culture of the net generation. The prankster roommates and high-tech surveillance criss cross with Mormon folklore and scripture in a hybrid bound to simultaneously upset and spellbind various audiences. But the through-line for the series is character, and this gives the series authenticity despite its obviously experimental nature. Jeremiah must resolve his aching need for an orienting identity. Ironically, that is what Mormonism is all about. Latter-day Saints claim an eternal identity; however, the media productions of Mormonism are seldom about feeling all the more lost and endangered for having a spiritual and eternal identity. This series sits on the edge of Mormonism, taking its ideas of eternal progression and individual mission so seriously that the stakes are realized in human terms, with evil as present and potent a reality as God. The protagonist of Jer3miah fights with his heritage and destiny--almost as though he is director Jeff Parkin's doppleganger. Parkin (pictured here), a popular and outspoken film professor at Brigham Young University, has called for more authenticity in Mormon storytelling (see his February 2009 university-wide lecture,“Story and Authentic Messengers: Meditations on Film, Originality and Poisonous Art") . Jer3miah is Parkin's proof of concept. The series has made waves among Latter-day Saints precisely because he has chosen to make Mormonism central to the storytelling: LDS youth really do feel a sense of destiny, they really hear and follow spiritual promptings, and they really do get in trouble in the process. Following God is displayed as a dangerous prospect in Jer3miah; not because religion is a fraud, but precisely because it isn't. I have heard people preach that discipleship is an adventure, but the idea takes on a whole new dimension when Jeremiah--held hostage at gunpoint--must choose between his girlfriend's life and breaking a sacred oath. Believe me, atheists and anti-Mormons will hang on for the resolution of any of the series' many cliffhangers like this. Parkin's creation swims upstream against the well-established modes of Mormon media, but there is a confidence to the production, a palpable enthusiam echoed in the fanbase and the ancillary media filling out the series folklore. Not all of this will succeed, but more than enough already has. Parkin is testing the adequacy of new media for cinematic storytelling and for his own religion. It is a brave series for all of that, with good omens for coming seasons. Comments This is a smart analysis of the Jer3miah series. I wonder what your impressions are of how technology is used in the Jer3miah narrative? While for the most part it is the bad guys that use smart phones, bluetooths, satellite imagining, and high-tech computers to advance their evil, there is a moment in episode 4 where Jeremiah gets a text message to his cell phone that is a message from God (or at least a message that God wants Jer3miah to hear)telling him he needs to essentially work to become trustworthy again to get the box back. I can't think of any other LDS examples of God communicating to man through text messaging. If there are some it is probably done in gist, but Jer3miah does it in all seriousness. Also, Jeremiah is often instructed and inspired to keep a record of his personal history, much like the people in the Book of Mormon, only with Jeremiah it is with a modern digital video camcorder. I bring this up because you are the first person I have seen that has really touched on Jer3miah's obvious and important ties to technology both in distribution and content and I was wondering what your extended thoughts on it were. Very good analysis of the show. I've kept up with the Buzz surrounding Jer3miah, and it's refreshing to read an editorial that doesn't merely state what the show "tries to be," but actually gives an insightful, and--from what I can tell--accurate explanation of what the show actually does. The show is definitely experimental, as you observed, not only in the way it delivers a Mormon Story, but the means by which it delivers the story, through a website, as well as with a parallel Alternate Reality Game that adds depth to the characters; and to the mystery. It's truly an innovative endeavor, and though not all of it's reviews are positive, one must, at least, acknowledge all that it has accomplished. It's been a tremendous effort, not only by Jeff Parkin, but the other faculty and students that worked so diligently to pull off the production demands of a weekly web-based show. Yes - great post! This is a great series and an incredible endeavor. I enjoyed the way you paralleled the series with the reality of living Church doctrine. I also loved the idea of following promptings and working our way through life as being an adventure. Jeff, Jared, and everyone have helped tell a great story with a Mormon essence. It's been a treat to see everything unfold.Survival and histological resolution of fibrosis in patients with autoimmune chronic active hepatitis. Survival and long-term clinical and histological outcome were assessed retrospectively in 33 patients treated for autoimmune chronic active hepatitis. The Mayo Clinic treatment criteria were met by 30 of 33 patients and histological signs indicating nodular fibrosis and/or cirrhosis were present in 16 of 33 (48%). An overall 10-year survival rate of 90% was found by life-table analysis. This was not significantly different from matched controls (92%). Paired liver biopsies revealed that 16 of 28 (57%) patients improved their fibrosis/cirrhosis category whereas none progressed in a follow-up biopsy performed a median of 49 months later. Furthermore, liver biopsy showed improvement in 9 of 14 patients with initial nodular fibrosis/cirrhosis and resolution of nodulation. When a semi-quantitative scoring system was applied, the median fibrosis score improved significantly. A key factor intervening in the progression of fibrosis seemed to be the reduction of inflammatory activity as a result of immunosuppressive treatment. We conclude that fibrosis may be resolved in autoimmune chronic active hepatitis following protracted and effective treatment which is initiated early in the course of the disease.Platypnoea-orthodeoxia syndrome post laparoscopic surgery in a patient with a patent foramen ovale. Platypnoea-orthodeoxia syndrome has the pathognomonic clinical findings of dyspnoea and arterial hypoxaemia relieved by recumbency. We report on a patient who presented with platypnoea-orthodeoxia syndrome post laparoscopic surgery. Platypnoea-orthodeoxia syndrome is an important diagnosis to consider when investigating hypoxia without an obvious cause.Film roll accumulating devices for forming a filmstrip into a film roll are typically used in the film take-up chamber of a camera or in a film cassette. As discussed in prior art U.S. Pat. No. 3,057,573, patented Oct. 9, 1962, it is desirable for the film take-up chamber of a camera to be expandable to accommodate enlargement of the film roll as additional film is fed into the take-up chamber. Similarly, it is desirable for the supply chamber of a film cassette to be expandable to accommodate enlargement of the film roll as additional film is fed into the supply chamber. Prior art U.S. Pat. No. 3,718,301, patented Feb. 27, 1973, discloses a film cassette in which an arcuate pressure shoe is slidably mounted in the cassette housing, and a spring urges the pressure shoe toward a front cover of the cassette housing. When the cartridge housing does not contain any film, the arcuate pressure shoe is relatively close to the front cover. When a filmstrip is first fed into the cartridge housing, the arcuate pressure shoe guides the filmstrip into a film roll having a small inside diameter. The pressure shoe is forced backwardly against the urging of the spring as the outside diameter of the film roll is increased by further feeding the filmstrip into the cartridge housing. Thus, the centerpoint or the center axis of the film roll shifts to accommodate enlargement of the film roll.Q: Can my asp.net dll's or pages can be affected by virus living in my pc Just curious to know that if my PC is infected with a Trojan or any other virus, is it possible that my website will be infected along with that I have made up in asp.net with visual studio 2008. I am not sure that it is the right place to put this question or shall I have to put it to https://stackapps.com/ or any other site linked to stackoverflow. But anyhow it is very important for me to know the answer. Because one gentleman report me about the infection of Jquery-
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1372, 1556, 7400, 37401, 2697, 1703, 13, 795, 8403, 376, 64, 3877, 740, 13, 387, 3285, 15, 1623, 2820, 281, 1973 ]	James Bradley Thayer, _The Origin and Scope of the American Doctrine of Constitutional Law_ , 7 HARV. L. REV. 129 (1893); West Virginia State Bd. of Educ. v. Barnette, 319 U.S. 624, 670 (1943) (Frankfurter, J., dissenting); BICKEL, LEAST DANGEROUS BRANCH, _supra_ note 49, at 16. _Cf._ Michael Stokes Paulsen, _Does the Constitution Prescribe Rules for Its Own Interpretation?_ , 103 NW. U. L. REV. 857 (2009). RICHARD A. POSNER, LAW, PRAGMATISM AND DEMOCRACY 234–47 (Harvard Univ. Press 2003). _See_ Gottlieb, _Compelling Governmental Interests_ , _supra_ note 68. _Compare_ Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 726–50 _with_ Gottlieb, _Compelling Governmental Interests_ , _supra_ note 68. _See also_ POWELL, MORAL TRADITION, _supra_ note 11, at 182–292; Robin L. West, _Are There Nothing but Texts in this Class? Interpreting the Interpretive Turns in Legal Thought_ , 76 CHI-KENT L. REV. 1125 (2000); Robin West, _Progressive and Conservative Constitutionalism_ , 88 MICH. L. REV. 641 (1990). FRIEDRICH NIETZSCHE, THUS SPOKE ZARATHUSTRA (Barnes & Noble Classics 2007) (1883–1885). See San Antonio Indep. Sch. Dist. v. Rodriguez, 411 U.S. 1, 49–50 (1973). _See, e.g._ , Clarence Thomas, _The Higher Law Background of the Privileges or Immunities Clause of the Fourteenth Amendment_ , 12 HARV. J. L. & PUB. POL'Y 63 (1989). WOOD, CREATION OF THE AMERICAN REPUBLIC, _supra_ note 46, at 24–25, 167–68. _See_ Locke, SECOND TREATISE, _supra_ note 34. Michael H. v. Gerald D., 491 U.S. 110, 163n (1989). _See_ POWELL, MORAL TRADITION, _supra_ note 11 at 182–292. _See_ Feinberg, _Civil Disobedience_ , _supra_ note 33, 2 HUMAN. IN SOC'Y at 45–58; _but see_ William Van Alstyne, _Clashing Visions of a "Living" Constitution: Of Opportunists and Obligationists_ , 2010–11 CATO SUP. CT. REV. 13. On the source of moral obligations, _see_ DAVID HUME, AN ENQUIRY CONCERNING THE PRINCIPLES OF MORALS 125–36 (1751) (Open Court Pub. Co. 1966). _See also_ James E. Fleming, _Living Originalism and Living Constitutionalism as Moral Readings of the American Constitution_ , 92 B.U. L. REV. 1171 (2012). Moore v. East Cleveland, 431 U.S. 494, 503 (1977). _Compare_ Exxon Shipping Co. v. Baker, 554 U.S. 471 (2008) _with id._ at 515 (Scalia, J., concurring), _and_ Pac. Mut. Life Ins. Co. v. Haslip, 499 U.S. 1, 25 (1991) (Scalia, J., concurring in the judgment). Dep't of Revenue v. Davis, 553 U.S. 328 (2008); United Haulers Ass'n v. Oneida-Herkimer Solid Waste Mgmt. Auth., 550 U.S. 330, 344, 342 (2007); Edmonson v. Leesville Concrete Co., 500 U.S. 614 (1991). Pac. Mut. Life Ins. Co. v. Haslip, 499 U.S. 1, 25 (1991) (Scalia, J., concurring in the judgment). Souter in Washington v. Glucksberg, 521 U.S. 702, 766 (1997) (Souter, J., concurring). Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 726. See Lawrence B. Solum, _The Unity of Interpretation_ , 90 B.U. L. REV. 551, 567–78 (2010); Andrew B. Coan, _The Irrelevance of Writtenness in Constitutional Interpretation_ , 158 U. PA. L. REV. 1025 (2010). Coan, _The Irrelevance of Writtenness_ , _supra_ note 90, 158 U. PA. L. REV. at 1090. _See_ Ran Hirschl, _The New Constitutionalism and the Judicialization of Pure Politics Worldwide_ , 75 FORDHAM L. REV. 721, 752 (2006); Richard Albert, _Why Judicial Review: A Preliminary Typology of Scholarly Arguments_ , INT'L J. CONST. L. BLOG, Mar. 25, 2013, http://www.iconnectblog.com/2013/03/why-judicial-review. _See_ Bond v. United States, 131 S. Ct. 2355, 2367 (2011); Alden v. Maine, 527 U.S. 706, 736 (1999); _and compare_ Nat'l League of Cities v. Usery, 426 U.S. 833 (1976) _with_ Garcia v. San Antonio Metro. Transit Auth., 469 U.S. 528 (1985). _Cf._ Paulsen, _Rules for Its Own Interpretation_ , _supra_ note 73. Stern v. Marshall, 131 S. Ct. 2594 (2011); Arizona Christian Sch. Tuition Org. v. Winn, 131 S. Ct. 1436 (2011); _and cf._ McDonald v. City of Chicago, 130 S. Ct. 3020, 3095n (2010) (Stevens, J., dissenting). U.S. CONST., art. I, sec. 2, par. 3. U.S. CONST., art. II, sec. 1,pars. 2–4. U.S. CONST., Amends. XIII, XIV, XV, XIX, XXIV and XXVI. CHARLES L. BLACK, JR., STRUCTURE AND RELATIONSHIP IN CONSTITUTIONAL LAW (Louisiana State Univ. Press 1969); _and see_ Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 721–25. _See_ Wesberry v. Sanders, 376 U.S. 1, 8 (1964). United States v. Carolene Products Co., 304 U.S. 144, 152n. 4 (1938). BLACK, STRUCTURE AND RELATIONSHIP, _supra_ note 99. Stephen E. Gottlieb, _Introduction: Overriding Public Values_ , _in_ PUBLIC VALUES IN CONSTITUTIONAL LAW 1 (Univ. Michigan Press, Stephen E. Gottlieb, ed. 1993). Abraham Lincoln, Gettysburg Address, Nov. 19, 1863. _See_ JAMES KENT, COMMENTARIES ON AMERICAN LAW, vol. 2, at 338 (Blackstone Publishing Co., William M. Lacy, ed. 1889); SIR EDWARD COKE, THE REPORTS OF SIR EDWARD COKE, vol. 6, at 280 (J. Butterworth and Son, John Henry Thomas and John Farquhar Fraser, eds. 1826); CHARLES VINER, A GENERAL ABRIDGMENT OF LAW AND EQUITY, ALPHABETICALLY DIGESTED UNDER PROPER TITLES; WITH NOTES AND REFERENCES TO THE WHOLE, vol. 15, at 534–35 (G. G. J. & J. Robinson, 1793); American Print Works v. Lawrence, 21 N.J. Law. (3 Zab.) 248, 258–59 (1847); Respublica v. Sparhawk, 1 U.S. (Dal.) 357, 362–63 (Pa. 1788). Alexander Hamilton, _The Vindication [of the funding system] No. III_ , _in_ SELECTED WRITINGS AND SPEECHES OF ALEXANDER HAMILTON 331, 333 (American Enterprise Inst. for Pub. Pol'y Research, Morton J. Frisch, ed. 1985). WOOD, CREATION OF THE AMERICAN REPUBLIC, _supra_ note 46, esp. the final chapter, _The Federalist Science of Politics_. Kathleen Sullivan, _Categorization, Balancing and Government Interests_ , in PUBLIC VALUES IN CONSTITUTIONAL LAW, _supra_ note 103, at 241. For the previous Court, see GOTTLIEB, MORALITY IMPOSED, _supra_ note10, at 29. On trying to build
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253, 6387, 273, 643, 4648, 273, 6868, 5576, 2144, 387, 253, 24390, 273, 247, 32019, 985, 285, 697, 22429, 15, 496, 14867, 8182, 434, 19361, 13, 19908, 40290, 9142, 6548, 281, 253, 1953, 273, 4495, 13, 3340, 281, 253, 1953, 273, 253, 4602, 875, 8928, 4495, 285, 19908, 830, 15, 187 ]	�漫漫涯涘。沒湫湫名溺沍涸名漫漶潦潦。 Cao's rhapsody insistently repeats one radical, thus luring the readerly mind away from the automatic connection between shape and meaning toward a graphic appreciation. Through repetition, it seems to achieve an analytical apperception, a pattern recognition on the level of character elements, and not, as in the normal reading process, on the level of the overall gestalt of a character that a reader then connects to a memory of meaning and sound. Cao's text displays a graphic variation of Roman Jakobson's definition of the poetic function of language: the application of paradigmatic criteria on a syntagmatic level. According to Jakobson, poetic word choice is dictated by contiguity with other signs, through either similarity or contrast. This becomes especially visible in the structural features of highly regulated literary forms, for instance, meter, rhyme, or alliteration in poetry. Jakobson's theory of the poetic function of language, developed in the cultural context of a phonetic script, tends to highlight phonetic repetition or contrast. However, Jakobson's theory is equally valid from a graphic point of view. In the context of sinographic texts, attention to graphic as well as phonetic repetition makes particular sense, because the modular character of the sinographs allows for the repetition of components on the level of the written sign in contrast to alphabetic or other phonetic scripts. What might be a largely unconscious process in the creation of Chinese texts, namely, that character choice is prompted by previously selected characters with similar elements or, on a phonetic level, similar pronunciation, comes to the forefront as a visible strategy in Cao's radical design. Cao's work draws attention to the materiality of language, illustrating with zeal (and some exaggeration) Roman Jakobson's definition of the poetic function of language, namely, the influence of syntagmatic combination on the selection of words or, in Cao's case, single characters. But the radical that Cao's rhapsody underlines stands out from other (sino)graphic components: not only does it have a meaning-bearing function, but it also turns out to be mimetic in character—after all, the three dots, or drops, of the radical visualize the idea of water and invoke the "view" or "contemplation" of the waves that the title promises. In other words, radical sinographic design, such as the repetition of radicals in Cao's text, can foreground a very limited aspect of the _techne_ of character construction, one that, though potentially analytical, might ultimately return to a mimetic myth of Chinese writing in a slightly updated form. Another type of experiment with the components of the graphic system of Chinese achieves its cultural anchorage by emphasizing meaning as well as _graphe_. This is the case in experiments that have a neographic, rather than a pseudographic, thrust; they avail themselves of ideographic principles to craft new characters whose meaning—though not part of the lexicalized vocabulary—is easy to guess. For instance, the mainland poet Yang Lian 楊煉 uses a neograph as the title of one of his most famous works, the long poem _Yi_ , published in 1989, a kind of _Yijing_ 易經 ( _Book of Changes_ ) for our times. Yang Lian himself calls the title of the work, _Yi_ , a "noncharacter" ( _wu zi zhi zi_ , 無字之字), and likens it on several occasions to Xu Bing's pseudographs. Unlike Xu Bing's graphic experiment, Yang Lian's newly crafted Chinese character is not devoid of meaning. Instead, the poet takes great pains to lexicalize it. The graph comes with its own pronunciation ( _yi_ ) and tone (first tone), as the poet indicates carefully at the beginning of his text, both in Pinyin transcription and in the older method of transliteration through two Chinese characters, in which the first indicates sound and the second tone, which is used mainly in commentaries on classical texts. Consisting of two pictographs, "人" ( _ren_ , "human being") and "日" ( _ri_ , "sun"), in a style reminiscent of ancient Chinese seal script, Yang's title combines two character (which are also radicals) to form a new one. As the connection of heaven and man, Yang Lian's _yi_ forms a counterpart to the _yi_ 易 of the _Yijing_. _Yi_ in the title of the classic is most commonly translated as "change," but its exegetes also point to the pictographic substratum of the character: a combination of "日" and "勿" (as an alternative form of _wu_ 物 or "animated thing"). Rather than a radical commentary on Chinese writing, Yang Lian's neographic intervention uses ideography, the combination of two pictographs, one of the six ways of character formation, the _liu shu_ 六書. The creative resources of the sinographic script subtly reinforce the meaning of the work as a whole: a repositioning of man in the universe. Rather than challenging the sinographic regime and its tradition, Yang Lian's neographic character displays the adaptability of Chinese writing, its openness to new meanings and ideas. By drawing on the Chinese tradition of the commentary, with its set ways of defining rare words, applied here to a neographism, Yang Lian's textual move inscribes itself within the long tradition of Chinese culture. However, by aligning himself with Xu Bing's graphic experiments, Yang Lian also advocates for a flexible, not slavish, use of Chinese tradition in order to enlarge its textual archive and enrich its sinographic medium. Whereas Yang Lian desires his "noncharacter" to be readable and goes to great lengths to achieve this, the Taiwanese poet Chen Li 陳黎 engages in a poetic reflection on the unreadability of pseudographs. One of the poems of his collection _Light/Slow_ ( _Qing/man_ 輕/慢), published in 2009, "A Difficult Poem That Is Easy to Read" ("Yi shou rongyi du de nan shi" 一首容易讀的難詩) contains four lines of cryptic characters. At first glance, Chen Li's strange characters seem to exhibit their unreadability. Chen Li had created the pseudographic text first in his earlier collection _Worries and Freedom Well-Tempered_ ( _Kunao yu ziyou de pingjunlü_ 苦惱與自由的平均律) where it had appeared on its own, just designated as "A Love Poem" ("Qingshi" 情詩). Now, the last lines of the text are recontextualized, imagined as an opaque Chinese poem cherished by Pindar, the famously difficult poet of Greek antiquity: He liked to read a Chinese poem called "Love Poem" because this poem, so they say, was equally difficult to read irrespective of if it was translated into Greek or not At face value, the poem's new frame, especially with its reference to Pindar, emphasizes the strange link between pseudographs and translation. Since these signs are "fake," they are not in need of translation; they are as cryptic to native readers of Chinese as to somebody who reads and writes in ancient Greek, such as Pindar. As in the case of Xu Bing's _A Book from the Sky_ , the opacity of pseudographic text transcends the limits of specific languages and is thus universal. However, Chen Li's poem presents such a translation as an actual possibility, even though, of course, the absence of meaning, or the fact that meaning is transferred to graphic form, makes these signs unique to their specific script. These look-alike characters on the one hand do not need translation, but on the other are untranslatable, since no adequate way of translating, or, indeed, transgraphing, pseudo-Chinese into pseudo-Greek exists. For Chen Li, pseudographs cannot simply signify the absence of signification or the impossibility of translation. The very gesture of framing part of the former stand-alone text of "A Love Poem" in a subsequent work almost remedies an earlier oversight, or else embodies a sustained manipulation of the reader. In _Light/Slow_ , a part of Chen Li's poems that are commentaries on individual Chinese characters is dedicated to glossing some of the supposedly inexistent Chinese signs from "A Love Poem" and "A Difficult Poem That Is Easy to Read," even supplying information on their voicing in his notes to the poems. After presenting these Chinese characters to readers as supposedly unintelligible sinographics, Chen Li provides them with meaning and cultural context: many of these signs turn out to be rare characters or to belong to the vocabulary of regions or ethnicities at the margins of Chinese culture. Irrespective of the facticity or fiction of these glosses, they open up the system of the Chinese script once we can read these signs (or imagine that we are reading them) not simply as spurious play that merely reactivates the rules of character construction, but as the possibility of other uses of sinographic material at the margins of a linguistic system and its norms. In Chen Li's poem, graphic experimentation ultimately returns to the question of meaning, especially to the question of the connection between cultural meaning and graphic form.
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594, 13, 253, 1781, 2170, 273, 17238, 327, 436, 36118, 313, 9887, 15, 470, 15, 3141, 1186, 10294, 63, 19, 11768, 390, 2074, 281, 2170, 327, 40814, 2205, 13140, 387, 470, 15, 1438, 1186, 10294, 63, 19, 40909, 544, 13206, 575, 19, 1084, 37075, 1166, 938, 1237, 39, 19, 910, 709, 14, 881, 568, 926, 7547, 310, 6405, 3146, 5998, 281, 452, 4516, 271, 3081, 5512, 1052, 1186, 933, 19050, 8557, 273, 2006, 860, 9114, 42151, 47701, 387, 5241, 17238, 15, 3308, 20904, 2006, 609, 13, 2167, 4390, 581, 273, 253, 6253, 2006, 860, 9114, 42151, 19014, 19665, 275, 31913, 39536, 13, 369, 6830, 598, 281, 7019, 347, 1781, 407, 5512, 31268, 17641, 685, 352, 310, 3063, 285, 14278, 273, 5512, 6783, 1186, 933, 19050, 8557, 387, 326, 673, 15, 844, 41661, 326, 436, 686, 12185, 2052, 2421, 8, 313, 66, 42151, 19014, 17562, 342, 3687, 685, 6783, 1186, 933, 46590, 10, 13368, 5415, 3116, 846, 3302, 32591, 387, 5512, 5307, 17641, 1919, 5512, 14212, 17641, 672, 352, 3407, 27177, 281, 697, 1246, 1979, 15, 187, 187, 1276, 2616, 497, 6276, 253, 2572, 275, 436, 42151, 19014, 686, 12185, 2052, 2421, 8, 1309, 436, 2180, 32, 5131, 3394, 275, 253, 13625, 11936, 387, 326, 673, 778, 1361, 5513, 436, 24045, 3116, 387, 20904, 2006, 609, 15, 4325, 35059, 281, 5307, 17641, 13, 253, 7493, 13153, 347, 973, 347, 643, 8593, 327, 42224, 4371, 285, 17179, 8451, 497, 13598, 407, 19050, 42151, 47701, 1309, 247, 5890, 2180, 1929, 347, 253, 42151, 19014, 686, 2178, 2751, 8, 1254, 37075, 1166, 938, 1237, 36, 24, 2947, 37075, 1166, 938, 1237, 36, 883, 2947, 37075, 1166, 938, 1237, 36, 805, 1656, 380, 7493, 13153, 369, 4336, 13966, 846, 27295, 283, 6914, 17641, 13, 342, 253, 25423, 2670, 387, 2398, 934, 11149, 2470, 13206, 575, 18, 1084, 37075, 1166, 938, 1237, 39, 18, 910, 709, 14, 881, 568, 926, 9471, 3164, 21681, 281, 247, 12356, 2180, 326, 4269, 2559, 3809, 6749, 326, 13230, 2289, 281, 29780, 2112, 436, 8852, 1282, 13, 13538, 42151, 47701, 432, 19050, 627, 1254, 37075, 1166, 938, 1237, 36, 805, 1656, 831, 3809, 6749, 275, 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14449, 17655, 313, 3832, 1186, 9913, 46590, 10, 285, 24369, 1342, 8451, 313, 746, 1186, 40896, 46590, 10, 1254, 37075, 1166, 938, 1237, 36, 23, 1656, 11474, 20904, 2006, 609, 556, 644, 6749, 14, 4924, 323, 6763, 273, 1107, 1254, 37075, 1166, 938, 1237, 36, 1010, 5413, 40814, 2205, 13140, 778, 417, 452, 644, 12482, 281, 19050, 42151, 47701, 2720, 281, 5307, 17641, 21681, 281, 697, 1698, 19099, 13, 8479, 352, 281, 320, 2057, 43923, 387, 5777, 2169, 6150, 1268, 390, 1512, 7329, 281, 9902, 919, 2510, 275, 253, 18384, 3408, 273, 253, 42151, 19014, 24571, 15, 7243, 253, 11600, 858, 2489, 12482, 13, 352, 369, 2104, 281, 1329, 3629, 3904, 273, 19050, 42151, 47701, 13, 3340, 342, 2440, 273, 253, 2169, 14, 11177, 15357, 42909, 334, 7736, 278, 2261, 326, 4390, 21191, 7338, 253, 11600, 15, 11474, 253, 5170, 36118, 812, 452, 644, 13598, 2720, 281, 5307, 17641, 13, 5662, 42909, 334, 7736, 22413, 452, 2568, 281, 320, 6888, 285, 3081, 5839, 310, 26085, 15, 187, 187, 998, 494, 43112, 941, 671, 5224, 326, 42151, 47701, 387, 20904, 14449, 17655, 285, 20904, 2006, 609, 21654, 3997, 3012, 625, 327, 36407, 408, 685, 49720, 13, 347, 4860, 407, 2406, 475, 10227, 8769, 1010, 63, 47, 2193, 275, 7238, 6384, 432, 841, 4375, 2429, 281, 2074, 3530, 432, 3939, 19665, 275, 253, 12324, 376, 30947, 6912, 285, 11053, 13625, 11936, 4811, 15, 4129, 253, 3410, 1979, 273, 4980, 7238, 6384, 432, 20904, 2006, 609, 310, 1355, 2796, 79, 11, 1186, 30, 1186, 22, 582, 841, 1543, 1329, 271, 4321, 1263, 327, 4980, 42151, 19014, 7238, 17901, 475, 10227, 8769, 1012, 63, 36, 285, 475, 10227, 8769, 1010, 63, 47, 432, 19665, 275, 253, 11053, 13625, 11936, 2429, 342, 20904, 14449, 17655, 281, 253, 6146, 326, 4860, 247, 625, 36407, 408, 14, 3169, 6196, 387, 436, 6158, 2670, 1254, 37075, 1166, 938, 1237, 36, 1036, 1656, 3900, 841, 2175, 327, 7238, 17901, 285, 6384, 760, 1957, 6196, 273, 5343, 42151, 47701, 2720, 281, 7238, 23157, 13, 643, 15048, 2175, 387, 4980, 285, 9129, 19665, 1329, 841, 15048, 3910, 875, 11186, 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14366, 22363, 84, 432, 42909, 334, 7736, 31344, 27960, 456, 387, 13966, 19665, 327, 13625, 8451, 671, 5224, 326, 47857, 9711, 12306, 2796, 49, 282, 321, 356, 83, 1861, 1331, 274, 10010, 360, 5627, 556, 644, 247, 2201, 4445, 273, 42151, 19014, 6196, 627, 323, 387, 1878, 253, 2469, 45660, 1254, 37075, 1166, 938, 1237, 36, 938, 1656, 187, 187, 15768, 253, 1029, 17787, 18053, 285, 36407, 408, 11659, 275, 253, 11186, 13625, 11936, 3063, 13, 534, 2616, 4269, 247, 10343, 275, 42151, 47701, 387, 20904, 2006, 609, 846, 253, 686, 12185, 2052, 2421, 8, 4925, 697, 4869, 6070, 407, 5512, 31268, 17641, 32, 844, 452, 642, 8813, 323, 436, 10343, 3707, 326, 352, 369, 3164, 2330, 342, 2544, 275, 5448, 6127, 13, 2329, 9208, 13, 285, 253, 1979, 273, 253, 13625, 11936, 877, 1362, 5973, 326, 9142, 5876, 17787, 18053, 1254, 37075, 1166, 938, 1237, 36, 1797, 1656, 1219, 350, 569, 273, 436, 3753, 452, 4269, 2264, 19050, 4433, 13, 17892, 8734, 3275, 285, 1029, 7891, 3394, 275, 2006, 860, 9114, 42151, 47701, 275, 253, 13625, 11936, 285, 5791, 31913, 39536, 1254, 37075, 1166, 938, 1237, 36, 1423, 2947, 37075, 1166, 938, 1237, 36, 1508, 1184, 285, 11440, 16274, 689, 3471, 1975, 673, 812, 906, 275, 17562, 10343, 390, 43289, 15, 380, 4942, 4864, 17238, 4860, 407, 253, 20126, 42909, 334, 7736, 31344, 326, 45589, 322, 21, 283, 52, 22, 327, 253, 5170, 36118, 8525, 436, 6452, 15, 187, 187, 51, 301, 2205, 13140, 4558, 4751, 13598, 387, 20904, 2006, 609, 3063, 13, 533, 253, 11600, 4558 ]	membrane than those from active colonies located farther to the south at Adélie Cove and Inexpressible Island at Terra Nova Bay (ANOVA, F~3~ = 41.8, p \< 0.001; [table 2](#RSOS172032TB2){ref-type="table"} and [figure 3](#RSOS172032F3){ref-type="fig"}). There was no difference in δ^15^N values between Cape Adare and Cape Hallett, or between Adélie Cove and Inexpressible Island. No differences in δ^13^C values occurred among all four sites (ANOVA, F~3~ = 1.2, p \> 0.32). Figure 3.Mean δ^13^C and δ^15^N isotope values from modern Adélie penguin egg membrane collected from four active penguin colonies in the Ross Sea. Samples from Cape Adare were collected in January 2005; all other samples were collected in January 2016. Error bars are one standard deviation. See the electronic supplementary material, table S1 for raw data. Table 2.Mean ± s.d. of stable isotope results of modern Adélie penguin egg membrane from four breeding colonies in the northern to central Ross Sea, Antarctica. (For each set of isotope values, shared letters (in superscript) indicate no significant differences in means (one-way ANOVA, F~3~ = 1.2, p \< 0.32 for δ^13^C, F~3~ = 41.8, p \< 0.001 for δ^15^N).)locationNδ^13^C (‰)δ^15^N (‰)Cape Adare5−25.0 ± 0.55^A^9.2 ± 0.38^A^Cape Hallett20−24.6 ± 0.55^A^9.1 ± 0.40^A^Adélie Cove15−24.6 ± 0.98^A^10.2 ± 0.27^B^Inexpressible Island21−24.3 ± 1.04^A^10.0 ± 0.30^B^ 4.. Discussion {#s4} ============== Our results suggest that Cape Adare, first occupied by breeding penguins at approximately 2000 BP \[[@RSOS172032C7]\] follows an expected colonization pattern with Ridley Beach completely occupied by approximately 1200 BP and remaining so today. Colonization of the upper terrace began by approximately 1700 BP with the most distant colonies to the south on this terrace occupied by approximately 1200 BP (based on median ages, [table 1](#RSOS172032TB1){ref-type="table"}), with at least some remaining active until approximately 800 BP. The relative brief occupation of these sites also is suggested by their relatively shallow (one level, or 5--8 cm) ornithogenic soils. Only the northern edge of this terrace overlooking Ridley Beach remains occupied today. Numerous other abandoned pebble mounds were located on the upper terrace at Cape Adare, but ground time was too limited in 2016 for additional sampling. We believe all of these sites, owing to their similar appearance on the surface, were colonized during the same sequence of occupation as S1--S5. If so, the large area of occupation on this terrace (approx. 0.78 km^2^, or similar to area on Ridley Beach at 0.80 km^2^; [figure 2](#RSOS172032F2){ref-type="fig"}) is conservatively estimated to have supported an additional approximately 200 000 breeding pairs of Adélie penguins at peak occupation. Thus Cape Adare, though currently one of the largest Adélie penguin colonies in Antarctica, was possibly up to twice as large by approximately 1200 BP than it is today and consisted of approximately 500 000 breeding pairs at that time. We hypothesize that this 'supercolony' (a penguin colony with greater than 500 000 nests) underwent continuous growth after initial colonization at approximately 2000 BP until approximately 800 BP when it began declining to its present size. What factors were driving the increase in this penguin 'supercolony' during this period? Other events in the Ross Sea at that time may help explain this hypothesized growth at Cape Adare. From 4000 to 2000 BP, the Scott Coast as well as other locations on Beaufort and Franklin Island were occupied by breeding penguins during a warm period known as the penguin 'optimum' \[[@RSOS172032C7],[@RSOS172032C11],[@RSOS172032C12]\]. The Scott Coast was completely abandoned after 3000--2000 BP, with the youngest site at Marble Point ([figure 1](#RSOS172032F1){ref-type="fig"}), probably owing to a cooling period that caused increased fast ice that blocked access to beaches along this coastline, preventing penguins from breeding there \[[@RSOS172032C12]\]. This fast ice in western McMurdo Sound persists well into the summer months today and the Scott Coast has remained abandoned by breeding penguins to the present. We hypothesize that colonization at Cape Adare began as the Scott Coast was being abandoned by approximately 2000 BP, signifying a large-scale movement of breeding penguins from the southern to the northern Ross Sea. Further, upwelling of Circumpolar Deep Water in the northern Ross Sea from the continental shelf break has maintained open water in the Ross Sea polynya near Cape Adare, along with the high marine productivity at the marginal ice zone \[[@RSOS172032C13],[@RSOS172032C14]\]. The northern Ross Sea and associated polynya have provided and continue to support large swarms of krill that in turn support large populations of breeding penguins that currently occur at Cape Adare, Cape Hallett (61 160 nests) and Coulman Island (19 437 nests) \[[@RSOS172032C6]\]. Though Cape Adare has been ice-free for thousands of years \[[@RSOS172032C15]\], Ridley Beach may not have been accessible to breeding penguins prior to 2000 BP owing to its low elevation, causing it to be either submerged at slightly higher sea level or too exposed to storm surges in the warming phase of the penguin optimum. Once the beach did become accessible, it was able to support increasing numbers of breeding penguins, especially with development of the higher-elevation ornithogenic mounds that currently transect the beach. Though the upper terrace could have been occupied prior to 2000 BP, older ornithogenic deposits have yet to be discovered and additional investigation is warranted. Stable isotope data also indicate that penguins at Cape Hallett and Cape Adare presently feed significantly more on krill than fishes, as indicated by lower δ^15^N values in egg membrane from these sites compared to similar samples from active colonies in the Terra Nova Bay and southern Ross Sea regions. Although the sample size of modern egg membrane from Cape Adare is small (n = 5), these results support an earlier study on modern penguin eggshell δ^13^C and δ^15^N from colonies in the southern Ross Sea compared with Cape Hallett to the north that indicated a more krill-based diet at this latter site \[[@RSOS172032C16]\]. While these studies on eggshell and membrane only represent diet of female penguins prior to egg laying, other dietary studies at modern and ancient colonies support these dietary differences between northern and southern colonies in the Ross Sea. For example, investigation of Adélie penguin diet at Cape Hallett, based on stomach flushing and contents \[[@RSOS172032C17]\], found that these penguins feed largely on krill during the guard stage of chick-rearing and prey increasingly on fishes as the season progresses. Satellite tracking of foraging penguins also revealed that most move to the continental shelf break. Moreover, stable isotope analyses of ancient penguin guano also suggest a diet based more on fishes in the southern Ross Sea during the Holocene \[[@RSOS172032C18]\] that persists with colonies on Ross Island today (colonies at Cape Royds, Bird and Crozier, [figure 1](#RSOS172032F1){ref-type="fig"}) \[[@RSOS172032C19]\]. Prey remains and otoliths from ornithogenic soils excavated at abandoned colonies on Ross Island also indicate that Antarctic silverfish (Pleuragramma antarcticum) has been a major component of penguin diet there for at least the past millennium \[[@RSOS172032C20]\]. Given the high marine productivity and krill availability in the northern Ross Sea today, which factors caused a decline in penguins at Cape Adare after the 'supercolony' reached its maximum extent by approximately 1200 BP? We have no explanation for this decline except that it was probably associated with changes in wind patterns, air temperatures, and the size of the Ross Sea polynya that ultimately affected marine productivity \[[@RSOS172032C21]\]. Alterations of this nature have caused total breeding failure, lowered chick production and high mortality events in Adélie penguins in the Ross Sea and East Antarctica \[[@RSOS172032C22],[@RSOS172032C23]\] and continuing impacts over geological time could result in colony decline or abandonment. The relatively brief occupation indicated by the shallow ornithogenic soils that characterizes S4--S5 on the upper terrace supports this conclusion. Ridley Beach remains fully occupied at Cape Adare today, but the beach remains
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"What call you that, musician?" The _rebeck_ player paused also, keeping his eyes downward submissively. "They call it smagdarite, Excellence. It comes from Sinde." "Sinned or no sin," echoed Birbal gaily, "the devil is in it. But 'tis a good name. Pass on Smagdarite! Stay"--here the old man half-hidden by his drum essayed to follow--"whom have we here? Old Deena the drum-banger! In what vile stew of Satanstown didst spend the night, villain?" Thus apostrophised, Deena's comically wicked, leering, old face hid itself completely in a salaam behind the drum, and came up again puckered with pure mischief. "That is a question for the virtuous Lord Chamberlain, Mirza Ibrahim," he replied, demurely. The sally was greeted with a boisterous laugh, and Mirza Ibrahim--whose fine clothes dispersed a perfect atmosphere of musk--scowled fiercely. For Satanstown, as ultimate exile of all the bad characters of the city was in his charge, and report had it that he pursued his duty of inspection with more than usual assiduity. "Sit thou here then, by Smagdarite," continued Birbal, recovering from his laugh, "and drum from a distance, lest thou be utterly damned for deserting honourable company. Hark! she begins!" Atma had by this time sunk to the ground beside the King. Her flimsy scarlet skirts curved about her like overblown poppy petals. Her dark eyes, full of fire, were fixed on the unconscious figure so close beside her, and, under the slow circling of her lissome forefinger the little drum held in her left hand was beginning to give out an indescribably mysterious sound like the first faint sobbing of air before an organ pipe breaks into a note. From the distance, almost unheard, came the muffled throbbing of old Deena's drum, and the thin thread of the _rebeck_, light yet insistent like a summer gnat; both kept to the same stern delicacy of rhythm. The singer's voice, high and clear, rose on it almost aggressively-- Hark! and hist! To the list Of the kings who have died In their pride, To the wide, wide, world. MIRUN-KHAN! Lo! He dreamt he was King! But he died In his pride To the wide, wide, world. SO HIS SON SULIMAN Dreamt the dreamings of kings Till he died In his pride To the wide, wide, world. SO THE DREAM WAS JEHAN'S! And he dreamt he was king Till he died In his pride To the wide, wide, world. The rhythmic background broke with the singing voice into troubled triplets, and the King's slack hands gripped in on themselves. Was he listening? Now the tale of the Kings who have died In their pride Is many, and many beside. But the dream is the same, So it came---- The pliant forefinger's whirling gave out a continuous boom like distant thunder amongst hills. Deena's drum throbbed a _reveille_, the _rebeck_ thrilled like a cicala-- TO KUMAN And he dreamt he was King In the wide, wide, world---- "Enough!" The word came swiftly as Akbar turned with a frown. "The end, woman? The end?" There was a pause; then from the very dust of his feet rose her reply: "There is none to the dreaming of kings!" "There is none--to the dreaming--of kings," he echoed slowly, and his eyes scanned her face curiously as he raised her from the ground. "Who art thou, woman?" he asked suddenly; then as suddenly dropped the hands he held, and said coldly: "Give her gold for her song." But once more a fresh feeling came to make him add: "Nay! not gold--let her choose her own reward--what wouldst thou, sister?" His face, grown soft as a woman's, looked sympathetically into hers; she stood before him abashed by the quick tie that seemed to have sprung up between them, unable to realise the chance that was hers. "Quick step!" cried Man Singh brutally. "See you not the Most-Gracious waits? What shall it be? Gold, fal-lals, dresses--the things for which women sell their souls?" She turned on him like a queen. "The women who nurture such heroes as Rajah Man Singh mayhap so sell them; but I----" here her recognition of opportunity swept trivialities before it, she drew herself up to her full height and faced both King and court, her voice ringing like a clarion. "I claim my father's office!" she cried. "Listen, O King-of-Kings! He gave you faithful service when you came to take the crown of India. What to him was Hindu or Mahommedan? He was the King's herald! Akbar was the King! His eldest son--my brother--died to save the honour of the Rajput chief he served before you came! And little Heera--son of his old age, begot _for you_, died ere his baby tongue had ceased to trip in challenging the world--_for you!_ Lo! I have kissed the words to steadiness upon his childish lips when father grew impatient! Why was I not the son? Hid in this dustlike body lies the spirit of my race. Is it my fault that in the dark months of my mother's womb, Fate made me woman, as she made you man? Give me my father's office, O my King, and if my tongue forgets one word of all my father's lore, or if I fail in guarding the King's honour, treat me as woman then--but not till then." The dying fall of her words left the court amazed, almost affronted. Here was a claim indeed! A claim foreign to the whole conservative fabric of Eastern society--which heaven knows had already suffered shock enough at the King's reforming hands! But Akbar took no heed of the looks around him; he was deep in that problem of Sex which was one of the many to claim his quick interest at all times. "The spirit of thy race is in thee, sure enough, O sister," he said slowly. "Manhood is in the woman, as womanhood is in the man--do I not know the latter to my cost? So take thy gift. Thou art the King's Charan from this day. But hearken! If thou failest in thy task, I treat thee not as woman--but as man." He turned away, dismissing her with an autocratic wave from sight, even from thought. "Ushers!" he went on, raising his voice in command, "Sound the advance! I go. And my Lord Chamberlain, bid the travelling Englishmen attend me in the Diwani-Khas. Abul! your arm; I would speak with you about this queen--this woman who has stretched her hand out over the seas to meet mine." He gave a quick joyous laugh and stretched out his own--the true Eastern hand, small, fine, but with a grip as of wrought iron in its slender, flexible fingers. "By God and his prophets I seem to feel it here--a woman's hand close clasped to mine." A fanfaronade of trumpets, shawms, and drums drowned his words, as with a waving of plumes, a blinding glitter of gold and jewels, the royal cortege of Akbar the Magnificent swept on its way. "One moment!" cried Birbal to Man Singh who awaited him impatiently, "I must find Smagdarite first." But both the _rebeck_ player and Atma Devi had gone. Only old Deena remained drumming softly; a fitting accompaniment to the murmurs which rose around him, as the immediate _entourage_ of the King disappeared. "Yet one more insult to Islam," muttered the Makhdum-ul'-mulk spitting fiercely ere he spoke. "And to honest men!" asserted a jealous old Turk who was suspicioned of having drowned more than one young wife on the sly, "for what is woman but ultimate deceit and guile?" "What?" echoed one whose calling could best be described as court-pand
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He also sells throwing axes, which can be upgraded into a great melee weapon. Increased the soul crafting cost of the extremely overpowered Celestriad. Craft this if you're ready to end the game in a very silly way. Increased the mana used by Starfall to 800. Map The Story of Red Cloud: Fixed a path that leads out of the new Meteorite Dungeon Slogra arena. It wasn't possible to go past before without the Shiny Red Balloon you get from the secret Earth temple. Now you can go this route with only the double jump ability. I also made the Skeletron arena a little less crazy with the skeleton summon statues. I improved the loot of a locked chest in the corruption temple and a couple other chests. Plus some other small things. 1.1o Mod The Tinkerer's Workshop is now sold by the Archeologist as well as the Goblin Tinkerer. Increased the health and damage of the Shadow Dragon. Attraidies' final form also spawns the Shadow Dragon at various times. 3 vanilla enemy lasers have received a damage buff, which has increased the difficulty of the Wall of Flesh, The Twins, the Destroyer, and Skeletron Prime. Mushrooms, Glowing Mushrooms and Goldfish no longer trigger potion sickness when used. (No more accidently eating one of these and dying because you meant to use a healing potion but one of these slipped into your inventory. :) To compensate, mushrooms and glowing mushrooms heal slightly less. Bloodred Moss Clump now heals 25 HP. Increased the difficulty of the Slogra and Gaibon boss fight. Increased spawn chance of Tetsujin in the SHM meteorite biome and from 7-9/10ths width of the map in the sky (more at night, more during blood moons). Map=== The Story of Red Cloud: Added a lot more housing under the village. Added the Tinkerer's Workshop to the village and in a couple other places. Added a couple more small shortcuts in the beginning area. Added a couple more torches to illuminate things you might not normally see depending on your lighting settings. Added a clue-sign in the Merchant's house. Finally decided to add a demon altar below the village. 1.1n Mod=== Increased the length of time between teleporting for all mage-type enemies (a highly requested feature). MP: Some mage enemies will no longer teleport to other players if they are far enough away. Rebalanced Molten Armor set upgrades (melee and magic specialization). They are both now roughly equal but different, and more powerful. Both cost 9000 souls. Added Ancient Dwarven Armor with an upgrade path both from Omnir's Mod. It's a custom melee set that you get from upgrading silver armor, +3 gold bars and 1500 souls. Nerfed Old Double Axe swing speed. Added Shadow Ninja set, a HM end-game tier set that is an upgrade of the Black Belt Gi set (needs 3 soul of fright and 40k souls). It also has a SHM upgrade. Fixed Longinus and it's upgrade not doing double damage when falling. Though I reduced it to 1.5x damage in this update. Removed toolTip that says it randomly heals for now. Removed 3 second "Curse" (can't use items) from Anti-Gravity Blast attack used by Attraidies and others. Increased difficulty of Attraidies. Slight nerf to Star Fall. Slightly buffed Ancient Dragon Lance. Maps=== Added IcyPRO's Minilands v4 - Iced! to the Sandbox Edition Maps folder. This is IcyPRO's updated minilands map, which has many new enhancements. With only 2 demon altars and everything taking place on mini-islands, this should prove to be quite a unique challenge. :) Leave your impressions, comments and more here: http://www.terrariaonline.com/threads/minilands-v4-iced.76761/ Goes without saying, a let's play of this map with the dark souls mod would be super cool to see. Story of Red Cloud: Added gold bars to the first dungeon to craft the upgraded silver armor. Added 2 signs. Added a torch to make gold armor easier to find. Added small short-cut near town well. 1.1m Mod Reduced soul cost of Slime Talisman from 1000 souls to 200 souls. Ancient Great Bow now auto-fires. MP: Fixed spawning of Hellkite Dragon, Seath the Scaleless and the Jungle Wyvern using their respective summoning item. Raised mana cost of Ice Tome 1 by 2 mana (it was pretty OP and still is awesome now - as good as the Bolt tomes). Increased difficulty slightly of Slogra and Gaibon. Increased difficulty and spawn rate slightly of Basalisk Walkers in the meteor biome at day and at night. MP: Fixed Giga Drill sprite not appearing correctly to other players. Increased soul cost of Forgotten Axe and Forgotten Great Axe. Fixed The Unknowable's tool tip about breathing underwater. Fixed Cruel Arrow error message and increased the arrow's speed and number of unique enemies it does 8x damage against. Map The Story of Red Cloud: Added water walking potions to the Eye boss battle in the secret Earth temple. Removed 30 Gravity Potions from Meteor Temple so players can't cheese the Slogra fight. You can now find jungle armor hidden in the meteor temple. Added a sign near eye battle for clarity. Added flippers to the end of the secret earth temple. Added 30 Regen potions to secret Hermes Boots location. Added more goodies to several other chests near the early game plus some other tweaks. Autosave Players is highly useful for MP to guard against player data loss from unexpected crashes. 1.1i Mod Nerfed damage and knockback of Diamond Pickaxe. You'll get this item when creating a new character with either of the Dark Souls Sandbox Editions loaded. Necromancer Elemental no longer drops Forgotten Ice Bow as I forgot I changed it to a end-game SHM weapon. Thorn Decapitator can now be auto-swung. Nerfed the debuffs of Shadow Orb, used primarily by Attraidies. Curse Buildup and Fracturing Armor only have a 1 in 8 chance and the rest are 1 in 2. Rebalanced Fire Spirit Tomes. They no longer pass through walls and fitting with the fire theme, cannot be shot underwater. They can now do critical hits however and have a high chance to light enemies on fire. Added Anomaly0.01's amazing custom sandbox adventure map "Elfheim: An Exploration Map" to the Sandbox Maps folder. This is a MUST-PLAY with the Dark Souls (Sandbox Edition) mod turned on! It is truly a wonderful map with incredible art direction on-par with the style and quality of The Story of Red Cloud map (if no one minds me saying so). :) The map uses an open, no rules sand-box format and everything in the Dark Souls mod is accessible. Give it a try and share your impressions. A let's play of this map/mod combo would also be excellent. Go here to visit the map's official thread: http://www.terrariaonline.com/threads/elfheim-an-exploration-map.102894/ Removed Map "Valley of Lord Gwyn" because it had become outdated compared to the changes made to Valley of Defilment and the updated version essentially provided a merged experience making this map obsolete. BIG THANKS! To Yorai for the inclusion of his Serverside Saving & Commands (SSS) mod. Check out his other awesome mods via the link above. To Anomaly0.01 for the inclusion of his amazing custom adventure map "Elfheim." 1.1h Mod Fixed Oswald of Carim - You couldn't talk to him before due to lacking the townNPC=True variable. Added Wand of Darkness II and Wand of Fire II. Added upgrade path for Fire Spirit Tome with 4 levels in total. Improved Ice 2 Tome. Increased spawning of infantry level dworcs with a slight spawn boost to voodoomasters and headhunters. Made dworcs unable to drown. Demonite Bars and Shadow Armor are craftable at Demon Altars now. Made Attraidies Relics stackable up to 100. Jungle enemies are now vulnerable to fire. In the Sandbox versions, when creating a new character, you now start out with better starting gear. :) Story of Red Cloud: Added "Travel to the Ends of the World Underground" side-quest. The challenge is to travel from the Western Ocean, enter through the sea floor, and travel all the way to the Underwater Observatory without going above ground.
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2592 ]	Using the Full Counting Statistics we computed the electronic current versus internal and external bias and reproduced electron-phonon-induced features such as oscillations versus the internal bias and signatures of Franck-Condon blockade. We stress that the description of this rich dynamics required only the four states of the double quantum dot to be taken into account dynamically. We have found that the dephasing rate of coherences in the pointer basis behaves in some regimes counter-intuitively as a function of the electron-phonon coupling strength. A simple intuitive explanation for this behaviour is that the Franck-Condon blockade stabilizes coherences, thereby also blocking transport through the DQD circuit. The analysis of the entropy production in the polaron master equation has allowed us to study the performance of the system when viewed as a thermoelectric generator converting a temperature gradient into electric power. We have found that in the strong-coupling regime, the system deviates strongly from tight-coupling between energy and matter current, and consequently, the efficiency for this process was found to be significantly below Carnot efficiency. Finally, we want to mention that our method can be generalized to more complex systems and thus allows applications in a variety of transport setups involving phonons such as molecules. Acknowledgments =============== T. B. and G. S. gratefully acknowledge financial support by the DFG (SFB 910, GRK 1588, SCHA ). M. E. has been supported by the National Research Fund, Luxembourg, in the frame of project . Polaron transformation {#App:PolaronTrafo} ====================== We consider the polaron transformation $$\begin{aligned} U=e^{{d_{\rm L}}^\dagger {d_{\rm L}}\mathcal{B}_{\rm L}+{d_{\rm R}}^\dagger {d_{\rm R}}\mathcal{B}_{\rm R}}\,,\end{aligned}$$ with the fermionic annihilation operators $d_\sigma$ and the bosonic operators $$\begin{aligned} \mathcal{B}_\sigma=\sum_q\left(\frac{h^\ast_{q,\sigma}}{\omega_q}a_q^\dagger-\frac{h_{q,\sigma}}{\omega_q}a_q\right)\end{aligned}$$ with bosonic annihilation operators $a_q$. To calculate the transformation rules, we recall the BCH relation $$\begin{aligned} e^X Y e^{-X}&=&\sum^\infty_{n=0}\frac{1}{n!}{{\left[X,Y\right]}}_n\,,\end{aligned}$$ with the short-hand notation ${{\left[X,Y\right]}}_{n+1}={{\left[X,{{\left[X,Y\right]}}_n\right]}}$ and ${{\left[X,Y\right]}}_0=Y$. We first note that the exponential in the polaron transformation can be written in a separated fashion $$\begin{aligned} U&=&e^{{d_{\rm L}}^\dagger{d_{\rm L}}\mathcal{B}_{\rm L}}e^{{d_{\rm R}}^\dagger{d_{\rm R}}\mathcal{B}_{\rm R}}e^{-{d_{\rm L}}^\dagger{d_{\rm L}}{d_{\rm R}}^\dagger{d_{\rm R}}{{\left[\mathcal{B}_{\rm L},\mathcal{B}_{\rm R}\right]}}/2}{\nonumber\\}&\equiv&U_{\rm L}U_{\rm R}U_{\rm LR}\,,{\nonumber\\}U_{\rm LR}&=&e^{{d_{\rm L}}^\dagger{d_{\rm L}}{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi}\,,{\nonumber\\}{\mathrm{i}}\Phi&\equiv&{{\left[\mathcal{B}_{\rm R},\mathcal{B}_{\rm L}\right]}}/2\,,\end{aligned}$$ where it is easy to show that $\Phi^\ast=\Phi$. Consequently, the adjoint operator is given by $$\begin{aligned} U^\dagger=U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}\,,\end{aligned}$$ and we note that ${{\left[U_{\rm LR},U_{\rm L}\right]}}={{\left[U_{\rm LR},U_{\rm R}\right]}}=0$. Alternatively, we can also split the unitary transformation according to $$\begin{aligned} U=U_{\rm R}U_{\rm L}U^\dagger_{\rm LR}\,,\quad U^\dagger=U_{\rm LR}U_{\rm L}^\dagger U_{\rm R}^\dagger\,,\end{aligned}$$ where again ${{\left[U_{\rm LR},U_{\rm L}^\dagger\right]}}={{\left[U_{\rm LR},U_{\rm R}^\dagger\right]}}=0$ holds. Left Mode Operators ------------------- We consider the action of the Polaron transformation on the left fermionic annihilation operator $$\begin{aligned} U{d_{\rm L}}U^\dagger&=&U_{\rm L}U_{\rm R}U_{\rm LR}{d_{\rm L}}U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}=U_{\rm L}U_{\rm LR}{d_{\rm L}}U^\dagger_{\rm LR}U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}{d_{\rm L}}e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} U^\dagger_{\rm L}=U_{\rm L}{d_{\rm L}}U^\dagger_{\rm L} e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi}{\nonumber\\}&=&{d_{\rm L}}e^{-\mathcal{B}_{\rm L}}e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ The left fermionic creation operator then transforms according to $$\begin{aligned} U{d_{\rm L}}^\dagger U^\dagger={d_{\rm L}}^\dagger e^{+\mathcal{B}_{\rm L}}e^{+{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ Right Mode Operators -------------------- In a similar fashion, we evaluate the transformation of the right fermionic annihilation operator $$\begin{aligned} U{d_{\rm R}}U^\dagger&=&U_{\rm R}U_{\rm L}U_{\rm LR}^\dagger {d_{\rm R}}U_{\rm LR}U^\dagger_{\rm L}U^\dagger_{\rm R}=U_{\rm R}U_{\rm LR}^\dagger{d_{\rm R}}U_{\rm LR}U^\dagger_{\rm R}{\nonumber\\}&=&U_{\rm R}{d_{\rm R}}e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} U^\dagger_{\rm R}=U_{\rm R}{d_{\rm R}}U^\dagger_{\rm R} e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi}{\nonumber\\}&=&{d_{\rm R}}e^{-\mathcal{B}_{\rm R}}e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} \,,\end{aligned}$$ and the adjoint operator becomes $$\begin{aligned} U{d_{\rm R}}^\dagger U^\dagger={d_{\rm R}}^\dagger e^{+\mathcal{B}_{\rm R}}e^{-{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ Bosonic Operators ----------------- For the bosonic annihilation operator we obtain $$\begin{aligned} U a_q U^\dagger&=&U_{\rm L}U_{\rm R}U_{\rm LR}a_q U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}=U_{\rm L}U_{\rm R}{d_{\rm L}}U^\dagger_{\rm R}U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}\left[a_q-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\right] U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}a_q U^\dagger_{\rm L}-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}{\nonumber\\}&=&a_q -\frac{h^\ast_{q,\rm L}}{\omega_q}{d_{\rm L}}^\dagger{d_{\rm L}}-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\end{aligned}$$ and similarly for the creation operator $$\begin{aligned} U a_q^\dagger U^\dagger=a_q^\dagger -\frac{h_{q,\rm L}}{\omega_q}{d_{\rm L}}^\dagger{d_{\rm L}}-\frac{h_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\,.\end{aligned}$$ Polaron transformation of the DQD Hamiltonian --------------------------------------------- The total Hamiltonian of the DQD is given by $$\begin{aligned} \mathcal{H} &=& \sum_{k\sigma} \upvarepsilon_{k\sigma} c_{k\sigma}^\dagger c_{k\sigma
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309, 858, 327, 436, 9455 ]	chief who would unite them as Qusayy had united Quraysh, and that there was no other solution to their problem. One of the leading men of the oasis, Abd Allah ibn Ubayy, was favoured by many as a possible king. He had not fought against Aws in the recent conflict but had withdrawn his men on the eve of the battle. He was none the less of Khazraj; and it was exceedingly doubtful whether Aws would be capable of accepting a king who was not of their tribe. The six men of Khazraj delivered the message of Islam to as many of their people as would listen to them; and the next summer, that is, in ad 621, five of them repeated their Pilgrimage, bringing with them seven others, two of whom were of Aws. At'Aqabah, these twelve men pledged themselves to the Prophet, and this pledge is known as the First Aqabah. In the words of one of them: "We pledged our allegiance to the Messenger of God on the night of the First Aqabah, that we would associate nothing with God, that we would neither steal, not commit fornication, nor slay our offspring nor utter slanders; and that we would not disobey him in that which was right. And he said to us: 'If ye fulfil this pledge, then Paradise is yours; and if ye commit one of these sins and then receive punishment for it in this world, that shall serve as expiation. And if ye conceal it until the Day of the Resurrection, then it is for God to punish or forgive, even as He will.' When they left for Yathrib the Prophet sent with them Musab of Abd ad-Dar who had by that time returned from Abyssinia. He was to recite the Koran to them and give them religious instruction. He lodged with As'ad ibn Zurarah, one of the six who had entered Islam the previous year. Mus'ab had also to lead the prayer because, despite their Islam, neither Aws nor Khazraj could yet endure to give one another that precedence. In reference to the practice which had developed in Arabia among the indigent Bedouin, especially in time of famine, of burying unwanted female infants. The rivalry between the descendants of the two sons of Qaylah was of long standing. There had been none the less frequent intermarriages between the two tribes, and as a result of one of these, Asad, the Khazrajite host of Mus'ab, was the first cousin of Sa'd ibn Mu'adh, chief of one of the clans of Aws. Sad strongly disapproved of the new religion. He was therefore angry, yet at the same time embarrassed, to see his cousin Asad together with Musab and some newly converted Muslims sitting one day in a garden in the midst of his people's territory, in earnest conversation with members of his clan. Determined to put an end to such activities, yet not wishing to be involved in any unpleasantness himself, he went to Usayd who was next in authority to himself, and said: "Go thou to these two men who have come to our quarters to make fools of our weaker brethren" - he was no doubt thinking of his younger brother, the now dead lyas, who had been the first man of Yathrib to enter Islam - "and drive them out; and forbid them to come to our quarters again. If Asad were not my kinsman I would save thee this trouble but he is my mother's sister's son, and I can do nothing against him." Usayd took his lance and went and stood over them and said, with as fierce an expression as he could muster: "What bringeth the two of you here, to make fools of our weaker brethren? Leave us, if ye have any care for your lives." Musab looked at him and said gently: "Why not be seated and hear what I have to say? Then, if it please thee, accept it; and if not, keep thyself clear of it." "That is fairly spoken," said Usayd, who liked both the appearance and the manner of the Prophet's envoy; and striking his lance in the ground he sat down beside them. Musab spoke to him about Islam and recited the Koran to him; and Usayd's expression changed, so that those who were present could see Islam in his face from the light that shone in it and the repose that softened it even before he spoke, "How excellent are these words and how beautiful!" he said, when Musab had finished. "What do ye do, if ye wish to enter this rehgion?" They told him that he must wash himself from head to foot in order to be purified, and that he must also purify his garments and then perform the prayer. There was a well in the garden where they were sitting, so he washed himself and purified his garments and testified There is no god but God and Muhammad is the Messenger of God. They showed him how to pray, and he prayed. Then he said: "There is a man behind me who, if he follow you, will be followed without fail by every man of his people, and I will send him to you now." So he went back to his clansmen, and even before he reached them they could see that he was a changed man. "What hast thou done?" said Sa'd. "I spake unto the two men," said Usayd, "and by God I saw no harm in them. But I forbade them to continue and they said: We will do as thou wilt.' "I see thou hast been of no avail," said Sad, taking the lance from his hand and setting off to where the believers were still sitting peacefully in the garden. He remonstrated with his cousin As'ad and upraided him for taking advantage of their kinship. But Musab intervened, speaking to him just as he had spoken to Usayd, whereupon Sa'd agreed to listen to him, and the result Was finally the same. When Sa'd had performed the prayer, he rejoined Usayd and those that were with him and together they went to the assembly of their people. Sa'd addressed them and said: "What know ye of my standing amongst you?" "Thou art our liege lord," they answered, "and the best of us in judgement, and the most auspicious in leadership." "Then I tell you," he said, "I swear I will speak neither to your men nor to your women until ye believe in God and His Messenger." And by nightfall there was no man or woman of his clan who had not entered Islam. Musab stayed with Asad for about eleven months, and many were the people who embraced Islam during that time. Then, when the month of the next Pilgrimage drew near, he returned to Mecca to give tidings to the Prophet of how he had fared among the various clans of Aws and Khazraj. The Prophet knew that the well watered land between two tracts of black stones which he had seen in a vision was Yathrib, and he knew that this time he too would be of the emigrants. Now there were few people in Mecca whom he trusted so much as his aunt by marriage, Umm al-Fadl. He was also certain that his uncle Abbas, although he had not entered Islam, would never betray him and never divulge a secret confided to him. So he told them both that he hoped to go and live in Yathrib and that much depended on the delegation which was expected from the oasis for the coming Pilgrimage. On hearing this, 'Abbas said that he felt it his duty to go with his nephew to meet the delegates and speak with them, and the Prophet agreed. Not long after Musab's departure, some of the Muslims of Yathrib set out upon the Pilgrimage as had been arranged between him and them, in all seventy-three men and two women, hoping to make contact with the Prophet. One of their leaders was a Khazrayite chief named Bara', and during the first days of the journey a preoccupying thought came over him. They were on their way towards Mecca wherein was the House of God, the Kabah, the greatest centre of pilgrimage for the whole of Arabia; and therein was also the Prophet, to whom they were going, and it was there that the Koran had been revealed, and thither their souls were moving ahead of them in aspiration. Was it then right or reasonable, when the time came for prayer, that they should turn their backs on that direction and face towards the north, towards Syria? This may have been more than a mere thought, for Bara' had only a few more months to live, and men who are near to death are sometimes gifted with premonitions. However that may be, he told his companions what was in his mind, whereupon they said that as far as they knew the Prophet was wont to pray towards Syria, that is towards Jerusalem, and they did not wish to differ from him. "I shall pray towards the Kabah," said Bara', and he did so throughout the journey, while all the others continued to pray towards Jerusalem. They remonstrated with him to no avail, except diat when they arrived in Mecca he had some misgivings and he said to Kab ibn Malik, one of his younger clansmen - and one of the more gifted poets of Yathrib: "Son of my brother, let us go to the Messenger of God and ask him about what I did on this journey
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language and topic to help keep this channel family friendly. <ubunubi> LieZ^: both dbus-x11 and dbus are both in the repo <hiptobecubic> i have ssh'd to another box using the -X flag to enable X11, but how can i start apps and have them show up on the remote display instead of my local display <ubunubi> LieZ^: and installed by default on my system anyway <LieZ^> are they? hold on a sec <teq> enmasse: yes <ra21vi> unop: filename is ${USER}.foo.bar would always be root.foo.bar when executed with sudo <herrmess> enmasse: System->Administration->Synaptic Package Manager-> Search for Privoxy <Shujah> enmasse, tor & privoxy are on ubuntu repos so should work without any tweaking? have you tried installing them <ubunubi> LieZ^: version 1.1.20-1ubuntu2 (for both) <herrmess> Both Privoxy and Tor are there, mark them for install. <enmasse> shuraj im confused on HOW TO install them <enmasse> okay will do herrmess, what i tried was going to the main site for tor and getting it from there <enmasse> what does this mean sudo apt-get install irssi? <teq> hey guys I think i fcked my repository how can i get it back? thanks <ubunubi> teq: we need more details than that <trashguy> enmasse, it istall the irc client irrsi <LieZ^> im getting package-dbus-x11 has no installation candidate? <enmasse> trashguy, i've installed the client where do i find it though? <Shujah> open gnome menu > system > administration > synaptic manager (search for tor) select press apply and so on <teq> ubunubi: packages that should be in the repo are not there <trashguy> enmasse, type irssi <unop> ra21vi, you shouln't call the same script itself, you need to call another script passing the filename as an argument - sorry if that name "myscript" mislead you <ubunubi> LieZ^: are you on an up-to-date hardy intsall? <teq> ubunubi: how can i reconfigure it? <rgb> crimsun: Copy? <LieZ^> ubuntu server my good man <izmeh> man, i'm loving linux <hlfshell> hey guys - trying to advise a friend with clonezilla. anyone know of a repository that has the package for it or am i going to have to walk him through installing it? <zyrorl_> izmeh - id love it more if i could somehow unlock draft-n wireless on it:S <ubunubi> LieZ^: dunno what to tell ya. both of them are showing installed, and in the repo and up to date for me, and i only have the default repo's turned on <perhamlinux> Gnea, are you there? <izmeh> zyrorl_: wish i could help ya <ubunubi> LieZ^: search for x11 and dbus with a space between them, and Name and Description turned on <ubunubi> LieZ^: in synaptic <solexious> [Q] Is there a ubuntu command line program to see the status of a jetdirect printer? <bayden> can movies run on ubuntu <LieZ^> soound like a noob mode, how do i get on synaptic im only used to working with CLI <ubunubi> bayden: sure if you install the correct codecs from mediabuntu <Shaba1> what type of movies bayden <ali__> hey guys <Shaba1> In other words what video formats are you talking about <ubunubi> LieZ^: do you have an X desktop environment setup? <ali__> its me enmasse on irssi <ali__> :D <bayden> well the dark knight <LieZ^> yes im on vnc and ssh now two connections <enmasse> hey im ali on irssi <bayden> a 2 or 3 hour movie <zyrorl_> bayden: if you mean porn yes. <ubunubi> LieZ^: just gksudo synaptic then <Shujah> enmasse had such a french seductive touch to it :( <zyrorl_> if you mean anything else, no it wont work <enmasse> lol <bayden> ooo where can i find tHAT <bayden> =) <bayden> LOL <zyrorl> just do an apt-get install vlc <zyrorl> it'll play anything <bayden> mediabuntu? <lenswipe> terminal keeps crashing when i start it, anyone got ny ideas?? <zyrorl> or mplayer but you'll probably want mplayer-gui as well <lenswipe> ï»¿terminal keeps crashing when i start it, anyone got ny ideas?? <monostone> I love xine <bayden> do i just download it then install it? <lenswipe> ï»¿terminal keeps crashing when i start it, anyone got ny ideas?? <rgb> zyrorl: It's also horrible with subtitle tracks. <zyrorl> or xine <monostone> it plays dvd isos, everything <ubunubi> !patience \| lens <ubottu> lens: The people here are volunteers, your attitude should reflect that. Answers are not always available. See http://wiki.ubuntu.com/IrcGuidelines <Shujah> lenswipe, have you edited the terminal profiles <zyrorl> rgb - i speak english... natively so i dont need subs <zyrorl> usually <lenswipe> Shujah: not that i know of... <teq> lenswipe: try sudo aptitude upgrade && update <zyrorl> but yeah vlc's subtitles rendering is horrible <overlordpuppy> Is there a mlt and mlt++ package? <lenswipe> teq: i cant, terminal keeps crashing... <acid2_> Shujah: that doesn't fix the fact that characters overlap with some fonts <ubunubi> lenswipe: you'll probably have to reboot into recovery mode <teq> ctrl+alt+f1 and then do that <rgb> zyrorl: Many English speakers require subtitles to watch certain content. Not every English Speaker watches only video in the English language. <Shaba1> I use vlc <lenswipe> ubunbi: and do what? <Shaba1> though I need to find another dvd burning program for windows <rgb> In my case, yeah I need my subtitles. <Shaba1> I have an old copy of nero vision experss that has seen its best days <lenswipe> ubuntubi: what do i do when im in recovery mode? <zyrorl> rgb: i can also speak portuguese natively, and am fluent in spanish and can understand french and german <LieZ^> ubunubi: must be something wrong with my repos its not showing <zyrorl> :P <zyrorl> i agree though... vlcs subs are pretty poor <rgb> zyrorl: Similar here, English, Dutch, German and French. <ubunubi> lenswipe: i'd assume delete your bash profile <rgb> zyrorl: Speak the first two, understand the latter. <zyrorl> i'm assuming you watch many asian movies? <rgb> zyrorl: Yup. <lenswipe> ubuntubi: and how do i do that? <zyrorl> fair enough <ubunubi> lenswipe:: try alt+f2, sudo gnome-terminal and see if it launches. if it does, it's just a matter of removing your user profile <aesonn> hello, anyone here have any experience using oracle 10g express on ubuntu? <lenswipe> ubuntubi: kk <Shujah> who was asking about the subs ? <rgb> zyrorl: Chinese and Japanese are a bit too hard to learn quickly at sufficient level. <ubunubi> lenswipe:: er gksudo gnome-terminal, sorry <
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The sham traction was given with a specially developed brace that tightens in the back during traction. To the patient, the experience is that of traction. The patients and outcome assessor were blinded for the assigned treatment. 151 patients with at least six weeks of non-specific low back pain were randomised. Intention to treat analysis showed no differences between the groups on all outcome measures (patients' global perceived effect, severity of main complaints, functional status and pain); all 95% confidence intervals included the value zero. The number of withdrawals from treatment, loss to follow-up, and protocol deviations was low. Consequently, the per-protocol analysis showed results similar to the intention to treat analysis. Subgroup analyses did not show any group for which traction might seem promising. Our data do not support the claim that traction is effective for patients with low back pain.Order Michigan Supreme Court Lansing, Michigan March 30, 2018 Stephen J. Markman, Chief Justice Brian K. Zahra Bridget M. McCormack 157340-2(97) David F. Viviano Richard H. Bernstein Kurtis T. Wilder Elizabeth T. Clement, MELISSA MAYS, MICHAEL ADAM MAYS, Justices JACQUELINE PEMBERTON, KEITH JOHN PEMBERTON, ELNORA CARTHAN, RHONDA KELSO, and ALL OTHERS SIMILARLY SITUATED Plaintiffs-Appellees, SC: 157340-2 v COA: 335555, 335725, 335726 Ct of Claims: 16-000017-MM GOVERNOR OF MICHIGAN, STATE OF MICHIGAN, DEPARTMENT OF ENVIRONMENTAL QUALITY, and DEPARTMENT OF HEALTH AND HUMAN SERVICES, Defendants-Appellees, and DARNELL EARLEY and JERRY AMBROSE, Defendants-Appellants, and CITY OF FLINT, Not Participating. _________________________________________/ On order of the Chief Justice, the motion of plaintiffs-appellees to extend the time for filing their answer to the application for leave to appeal is GRANTED. The answer will be accepted for filing if submitted on or before May 3, 2018. I, Larry S. Royster, Clerk of the Michigan Supreme Court, certify that the foregoing is a true and complete copy of the order entered at the direction of the Court. March 30, 2018 Clerk import React, { useCallback, useContext, useState } from "react"; import { UploadyContext, useBatchAbortListener, useBatchStartListener } from "@rpldy/shared-ui"; const StoryAbortButton = () => { const context = useContext(UploadyContext); const [uploadingId, setUploading] = useState(null); useBatchStartListener((batch) => { setUploading(batch.id); }); useBatchAbortListener((batch) => { console.log(">>>>> StoryAbortButton - (hook) BATCH ABORT - ", batch); }); const onClick = useCallback(() => { context.abortBatch(uploadingId); }, [context, uploadingId]); return context && uploadingId ? <button onClick={onClick} data-test="story-abort-button">Abort</button> : null; }; export default StoryAbortButton; Tag: role People have different views about the role and function of museums. In my opinion, museums can and should be both entertaining and educational. On the one hand, it can be argued that the main role of a museum is to entertain. Museums are tourist attractions, and their aim is to exhibit a collection of interesting […] Every person holds a very important place in a society and their actions towards the laws and norms effect the whole system in numerous ways.Its vital to play a positive role in order to create a constructive environment for individuals.As much as optimistic and genuine opinions have a great impact in boosting confidence towards each […] In these days, numbers and statistics have bigger voice than insubstantial aspects of our life. It is under this circumstance where the numerable academic achievement of each school has been stressed. At one extreme, some people argue that the role of school teacher is to just impart textbook knowledge to his/her pupils. However, this impoverished […] There is no shortage of debate about whether today’s extended family still play a pivotal role or not. In my opinion, that the role of relatives was not crucial than it once was. I feel this way for two main reasons, which I will explore in the following essay. First of all, certain roles once […] People in our time have more opportunities to succeed but they also have to face more fatal competition. Success in every aspect of the society requires extraordinary efforts in addition to some luck and various kinds of social network since we are living in an age which emphasizes team work and cooperation between each other. […] The statement is flawed due to its downplaying the role of school or college in cultivating students, as far as I am concerned. It’s reasonable to associate personal discipline with great significance concerning learning knowledge, but there are still considerable students lacking motivation in need of timely and appropriate guidance from their teachers as well […] There is no shortage of debates about whether we should play a role as a leader or an individual player, and each view has its own strengths and weaknesses. Personally, I am of the opinion that people should lead a team rather than follow other members. I feel this way for two main reasons, which […] It is common to argue about who should be the best teacher between family or school, indeed, this issue is born consequently at the lost of teachers’ importance. Nowadays parents have a crucial position in education while in the past was ordinary to combine the two figures. There are people against or in favor the […] Nowadays, social networks and television play such an important role in society that they have created certain stereotypes which makes it difficult to determine what is really worth about a person. Therefore, social status is attributed by how many likes people have on their posts on Facebook or how many followers they have on Instagram. […] The statement given by the author itself is a debatable one as it won’t have any definite answer as many people would have different opinions. Parents are the two most important building blocks for every living beings on this planet. A teacher is one who is always looked at for help guidance and also for […]Thursday, June 2, 2016 This book gives you “more” of what you need 4 stars The More of Less: Finding the Life you Want Under Everything You Own by Joshua Becker This month’s review is from my husband, who is striving to be a minimalist in a world full of stuff… In the American culture today, stuff can dictate our lives. We feel we must work hard to keep up with others and their stuff, so we put too much value on possessions over deep relationships. But in this book, author Joshua Becker teaches how one can become a minimalist at heart and find happiness in less. He offers practical baby steps in how to downsize, taking the fear of getting rid of everything all at once. He says 80% of what is in our house we only use 20% of the time. So why do we have all the stuff? This book helps one evaluate what they have and asks hard questions like: What if, instead of being embarrassed over the type of car we drive, we became embarrassed over how often we take the luxury of automobile ownership for granted? What if, instead of being embarrassed because our house seems too small, we became embarrassed over the amount of unused space within it? What if, instead of being embarrassed over the brand of our clothing, we became embarrassed over the enormity of our walk-in closet? Overall, this book helps readers see the world of excess and reminds us as Christian how we are to live differently than the world and find happiness not in stuff, but of the things of God. *I received this book for free from Blogging for Books for this unbiasedDimeric trigger factor stably binds folding-competent intermediates and cooperates with the DnaK-DnaJ-GrpE chaperone system to allow refolding. Trigger factor (TF) is the first chaperone encountered by the nascent chain in bacteria and forms a stoichiometric complex with the ribosome. However, the functional significance of the high cytosolic concentration of uncomplexed TF, the majority of which is dimeric, is unknown. To gain insight into TF function, we investigated the TF concentration dependence of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) reactivation yield in the presence and absence of the DnaK-DnaJ-GrpE chaperone
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1198, 436, 1650, 13, 970, 25852, 1162, 355, 457, 84, 29562, 2351, 12968, 13, 253, 4839, 273, 23453, 247, 3221, 4602, 310, 370, 805, 15, 22, 19182, 1366, 1223, 970, 776, 1332, 352, 310, 1199, 2406, 387, 370, 21, 15, 19, 19182, 1352, 496, 3946, 436, 651, 5321, 253, 8607, 271, 14779, 2408 ]	Connectivity Map with this signature can be found in the supplementary data, which suggests that rds02 has positive connections to $107$ reference profiles, and negative connections to $119$ profiles. However once again we know these must be all false connections. Conversely, the new method presented in this paper gave results that agree with the underlying truth. With the criteria set above there was 1 connection found significant ($p<1/453=0.0022$). Since we expect on average 1 false connection, this declared significant connection can be taken as false. The two examples of random gene signatures above revealed that on the individual treatment instance level Lamb et al’s Connectivity Map gave many false connections because no safeguard was provided for these. The reason for this was in the way the connectivity scores were calculated. Briefly, Lamb et al’s connectivity score was based on the Kolmogorov-Smirnov statistic. At first two K-S statistics were calculated, one for the up-regulated genes, and one for the down-regulated, then these two values were combined to give a single connectivity score. This way of defining the connection score was unnecessarily complex, which made the calculation of a possible p-value on an individual level difficult, if not impossible. rank Compound ID score pvalue ---------- -------------- ---------- ---------- -------- 1 (-)-catechin 1101 0.334 0.003 2 sirolimus 1022 0.312 0.006 3 phentolamine 1138 0.309 0.007 4 5162773 892 0.292 0.011 5 resveratrol 595 0.286 0.013 $\cdots$ $\cdots$ $\cdots$ $\cdots$ 451 felodipine 848 -0.002 0.988 452 estradiol 988 -0.001 0.991 453 bucladesine 959 0.001 0.993 : \[tab-rds01-sdz\] The connection scores for the random gene signature rds01 using the new methods. To control the expected number of false connections at 1, the threshold p value was set at $1/453=0.0022$. No connection was found to be significant, which agrees with the underlying truth. On the treatment set level, Lamb et al’s Connectivity Map provides a permutation p value when a set of treatment instances associated with the same compound were viewed as a whole. The permutation p value was calculated by comparing a statistic (again based on K-S statistic) of the treatment set with the distribution of many random-set statistics. Those random sets were formed by randomly selecting treatment instances from all instances. From the way the permutation p value was calculated, it was clear that the following null hypothesis was being tested: [The set of instances in question have the same pattern (distribution) of connections with the query gene signature compared with a randomly formed set of the same size.]{} A null hypothesis such as this is not the most appropriate one to test, because it is not directly relevant to the question of whether the query gene signature had any real biological connection to the treatment set. Lamb et al themselves also recognized that more rigorous methods for the estimation of statistical significance were probably required[@Lamb-etal-Science-2006]. Putting its appropriateness aside, if we do use the permutation p values from Lamb et al’s Connectivity Map to control false connections, the same criteria for setting threshold p value can be used. The results of significance analysis on the connections between the two random gene signatures and the $164$ treatments sets can be found in the supplementary data. In this instance both connectivity maps gave the right answers for these two random gene signatures. However, for Lamb et al’s Connectivity Map permutation p values were not available for all the $164$ treatment sets. For those treatment sets which only contain $1$ treatment instance or those sets with mean connectivity score $0$, no permutation p values could be calculated, and hence no statistical significance. This problem affects the coverage and consequently the sensitivity of Lamb et al’s Connectivity Map, because real biological connections between a query gene signature and any of those treatment sets may not be recognized. Querying the connectivity maps with experimentally derived real gene signatures ------------------------------------------------------------------------------- ![HDAC inhibitor gene signature: The Venn diagram summarizing the findings of significant connections as identified by the connectivity maps. A represents the instance-level analysis using the new method; B, the set-level analysis using the new method; C, the set-level analysis using Lamb et al’s Connectivity Map. The label “AB 13” means that $13$ compounds are identified as significant solely by A and B (not C), “B 4” means that $4$ compounds are identified as significant solely by B (not A, not C), and so on. The areas are approximately proportional to the numbers they represent.[]{data-label="fig-HDAC"}](HDAC.eps){width="8.5cm"} ### HDAC inhibitors To test the ability of the new method for identifying real biological connections we utilized some of the same examples used in [@Lamb-etal-Science-2006] to compare with Lamb et al’s Connectivity Map. The first example was a gene signature of histone deacetylase (HDAC) inhibitors (Lamb’s gene signature sigs01), which was compiled from [@Glaser-etal-MolCancerTher-2003] on the responses of T24, MDA435 and MDA468 cells respectively to three histone deacetylase (HDAC) inhibitors: vorinostat, MS-27-275, and trichostatin A. This gene signature consisted of 8 up- and 5 down-regulated genes, represented by $25$ Affymetrix probe-set IDs on the Affymetrix HG-U133A microarrays. As Lamb et al’s Connectivity Map does not provide any safeguard on individual treatment instance level against possible false connections, we can only use the results of Lamb et al’s Connectivity Map on the treatment set level. In total 6 compounds (vorinostat, trichostatin A, resveratrol, geldanamycin, valproic acid, and 17AAG) were identified to have significant positive connectivity with the HDAC inhibitor gene signature; and 2 compounds (5182598 and fludrocortisone) had significant negative connectivity. Vorinostat, trichostatin A, and valproic acid are known HDAC inhibitors thus the identification of these can be regarded as a success. However another known HDAC inhibitor HC-toxin, a reference profile of which was contained in the database, was not identified. This happened because there was only one treatment instance of the compound HC-toxin in the database and so no permutation p value could be obtained using Lamb et al’s method. Based on their instance level results, Lamb et al highlighted HC-Toxin in [@Lamb-etal-Science-2006] as it had the 7th highest connectivity score (0.914) of all instances in the dataset. However, as the two examples of random gene signatures showed Lamb et al’s instance level analysis gave false connections even for the highest connectivity scores 1.0. So the rational choice is to disregard the instance level results from Lamb et al’s Connectivity Map. We used this same HDAC inhibitor gene signature to query the new connectivity map presented here, with p values calculated at both the individual instance level and the treatment set level. $56$ treatment instances, representing $22$ distinct compounds, were found to have significant connections to sigs01. On the treatment set level $24$ compounds were found to have significant connections with the signature. Near the top of the significant connection list were those known HDAC inhibitors highlighted in [@Lamb-etal-Science-2006]. Importantly though also included in the output was HC-Toxin, which was not identified by the set-level analysis Lamb et al’s Connectivity Map. The full results of querying both connectivity maps using the HDAC inhibitor gene signature are included in the supplementary data. In Fig. \[fig-HDAC\], we summarize the number of significant connections as identified by: (A) Instance level analysis using the new method presented here; (B) Set level analysis using the new method; (C) Set level analysis using Lamb et al’s Connectivity Map. In total, our method (A) and (B) combined identified 27 compounds and Lamb et al’s Connectivity Map identified 8 compounds, as having significant connections to the HDAC inhibitors. Our method missed only 1 of the 8 compounds found significant by Lamb et al’s Connectivity Map, while the latter missed 20 of the 27 compounds identified by our method, with HC-toxin among the 20 compounds that were missed. The HDAC inhibitors example thus shows that our new method is more sensitive at detecting real connections. With the increased sensitivity and false connections being properly controlled, the potential benefit of our method is obvious. In this example, the set-level analysis of Lamb et al’s Connectivity Map identified 8 compounds with a false discovery rate of $12.5\%$ (1/8), while the set-level analysis using our method identified 24 compounds with a false discovery rate of $4.2\%$ (1/24). Based on the findings of the connectivity maps, researchers can prioritize a small sub set of those compounds for further investigations and/or developing new biological hypotheses. For this example, using Lamb et al’s Connectivity Map, the chance of pursuing a false connection is $12.5\%$, while using our method it is much lower at $4.2\%$. In practice this would save the researchers an enormous amount
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347, 3192, 327, 2710, 643, 23768, 432, 643, 8548, 15, 187, 187, 42, 671, 1728, 14, 23081, 366, 619, 767, 2151, 342, 253, 1361, 273, 619, 7832, 285, 717, 7730, 281, 247, 14898, 534, 556, 616, 1682, 6284, 387, 2798, 15, 380, 958, 326, 309, 6947, 594, 1199, 673, 342, 619, 5753, 285 ]	lose. Over all it really doesn't affect my daily life like being blind or deaf would. Silver linings, you know. ;) Well I can answer this because for the last three months I have not been able to smell due to sinitus infection that just wont go away. Although I am not as hungry and do not crave food I stil eat what I fancy and the body recalls the taste and smell of the food. I could be eatting anything! Although I can not taste at all my brain kicks in and tells me what it is supposed to taste like. It is very depressing I can tell you! Although not being able to smell does have its advantages. My husband has done all the cooking because I am a danger in the kitchen. If I place bread under the grill it would catch fire or burn because I simply get distracted and cant smell it. I can not season food or cook from scratch as I have no idea what it tastes like! And best of all if the puppy poops behind the chair I cant smell it, so my husband cleans that up as well. Its that pleasure pain thing! I am hoping for a full recovery soon as eatting is so boring without the smell and tastes of the food I love.Story highlights Sen. Sanders said Monday that health care is a "right, not a privilege" Sanders spoke to the NAACP national convention Washington (CNN) Sen. Bernie Sanders slammed Senate Republicans' health care bill as "destructive" and "irresponsible" in a speech at the NAACP national convention in Baltimore on Monday. Calling the bill the "cruelest, most destructive and irresponsible piece of legislation ever brought to the United States Senate in the modern history of this country," Sanders highlighted the possible effects of the bill's provisions, which include cutting Medicaid, defunding Planned Parenthood and roadblocks for those with pre-existing conditions. Sanders also criticized Republicans for not holding hearings on the bill and writing it "behind closed doors." "This legislation is overwhelmingly opposed by the American people, overwhelming opposed by virtually every health care organization in this country," Sanders said, listing a number of organizations that oppose the bill, including AARP and the American Cancer Society. Sanders' remarks were a part of the conference's policy discussions, which included a panel of Democratic legislators such as Maryland Sen. Ben Cardin, Illinois Sen. Tammy Duckworth, California Sen. Kamala Harris, Virginia Rep. Bobby Scott, and Texas Rep. Sheila Jackson Lee as well as Republican Virginia Rep. Scott Taylor. Read MoreMaduromycosis of the brain. Case report. A rare case of a gas-containing brain abscess due to verified maduromycosis is described. Blackish material over the abscess cavity revealed the fungal elements. The pus from the abscess contained Streptococcus hemolyticus and Klebsiella organisms.This invention is directed at reducing cravings in mammals. More specifically the present invention is directed at reducing the cravings of a mammal to any dopamine mediated cravings including food or addictive substances. Considerable research has been directed at obesity, nicotine addiction and substance abuse. The cost to society is very high from the health costs associated with obesity, tobacco consumption, and drug and alcohol abuse. While many individuals choose to lose weight, stop smoking and/or cease abusing drugs or alcohol, they frequently relapse into their former patterns of behavior during or shortly after they complete their treatment programs. Often this may be caused by subtle signals in the environment which initiate cravings in the individual for food or the substance which they had abused. Accordingly, it would be desirable to provide a substance which would suppress cravings for food and/or abused substances in a predisposed mammal. The use of D.sub.1 antagonists in the treatment of drug abuse is known. U.S. Pat. Nos. 4,973,586 and 5,302,716 disclose the use of D.sub.1 antagonists in treating drug dependence. A dosage range of 0.02-10 mg/kg was suggested, with 2.0 mg/kg divided over 1-3 administrations per day being particularly preferred. Spealman, et al., Neurochem. Int. Vol. 20 Suppl., 99147S-152S (1992) discloses that cocaine is a robust reinforcer and often is used as a standard for evaluating the reinforcing effects of other drugs. When SCH 39166 was administered to monkeys, a 3-fold or greater increase in the dose of cocaine usually was required to restore characteristic self-administration performances. Barrett-Larimore and Spealman in Society for Neuroscience Abstracts 22(2): 92 5 (1996) reported that several compounds including the D.sub.1 antagonist SCH 39166, a D.sub.2 antagonist and a D.sub.3 /D.sub.4 antagonist all were able to attenuate the cocaine-seeking behavior in a cocaine relapse model. Clifton, 1995 and Clifton, 1991 have indicated that the D.sub.1 antagonists SCH39166 and SCH 23390 have no effect on total food intake, meal size or feeding rate up to 3 mg/kg. Caine and Koob in The Journal of Pharmacology and Experimental Therapeutics Vol. 270, No. 1 pp. 209-218 (1994) describe tests on D.sub.1 antagonists SCH 39166 and SCH 23390 for cocaine and food self-reinforcement. D1 antagonists were found to affect cocaine self-administration. Chausmer and Ettenberg in Pharmacology Biochemistry and Behavior Vol. 57, No. 4, pp. 681-685 (1997) conducted tests on D.sub.1 and D2 antagonists in response re-instatement properties of food reward. They found that the D.sub.2 antagonist raclopride was sufficient to block the response-reinstating effects of food reinforcement, but the D.sub.1 antagonist SCH 39166 was not. Nathan, Breskin and Batki in CNS Drugs Jul. 10, 1998 (1) pp. 43-59 summarize results in treating cocaine addiction with various drugs. Lancet, Volume 347 pp. 504-508 (Feb. 14, 1996) reports that haloperidol was tested for decreasing desire for an abused substance. However, this compound is reported to have had significant adverse side effects, such as dysphoria, restlessness or stiffness, which reduces the desire for individuals to take them. It has been difficult to develop substances which inhibit craving in mammals, particularly humans, because of the lack of reliable animal models which correlate well with human behavior. Substances which are administered to reduce craving should not produce significant physiological effects, such as stimulation of mood or elevate blood pressure or heart rate. This could result in the substitution of one abused substance for another. Compounds which dampen the desire for the abused substance also should not exacerbate the physiological symptoms of the abused substance in the event the individual relapses and takes the abused substance. Substances administered to reduce craving also should not produce significant adverse affects, such as dysphoria, restlessness or stiffness. Accordingly, it is desirable to provide a compound and method of treatment which will be active in reducing craving for the abused substance, and which does not exacerbate the sympathetic response rate caused by the abused substance and which has favorable pharmacodynamic effects. It also is desirable to provide a compound and method of treatment which blocks the euphoric and dysphoric effects of the abused substance.Naomi C. Writer and researcher Plymouth, United Kingdom I can offer fantastic rates on a wide variety of article writing assignments, with a fresh and engaging style which is perfect for organisations and businesses that are a little...Read moreI can offer fantastic rates on a wide variety of article writing assignments, with a fresh and engaging style which is perfect for organisations and businesses that are a little different from the mainstream. Discounts are available for charities, so please get in touch to discuss your requirements. I have been working as a freelance writer and researcher since 2010 providing SEO, web content and high quality articles for a wide variety of high profile clients. I also home-educate my two children with the help of my partner and am committed to a lifestyle which has their best interests at heart. The fact that I spend so much time with my kids and engage in many creative and play based activities throughout the day gives my work a focus and insight which is unique yet incredibly accessible. As a supplement to my writing income, I work as a storyteller and independent ambassador for Barefoot Books. Barefoot Books began with two mothers who wanted their children to have books that would feed the imagination, while instilling a respect for diversity and a love of the planet. I am part of a world-wide community of writers, artists, storytellers, musicians, and others who are committed to providing timeless stories and captivating art that can help children become happy, engaged members of a global society. Area Covered: Global Industry: Outsourcing/Offshoring Employees: 1 Work Experience ----------------- Summary: I have been home-shoring for a number of years and have covered a wide variety of different fields including call-center work, customer services and direct sales. Literature is one of my greatest loves, so it was a natural progression for me to become a freelance writer and I have worked with the same company since 2010 as well as taking on various other assignments from other clients. I also home-educate my two children with the help of my partner and am committed to a lifestyle which has their best interests at heart. The fact that I spend so much time with my kids and
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342, 352, 32, 309, 452, 3597, 281, 12119, 964, 11368, 13, 964, 8567, 13, 964, 23200, 9508, 15, 4410, 301, 253, 10651, 285, 1160, 247, 4228, 3168, 4114, 15, 309, 1849, 2218, 352, 512, 1051, 309, 1158, 15, 6101, 2915, 452 ]	) - Mitsubishi UFJ Financial Group Inc (MUFG) on Wednesday sued New York’s banking regulator to stop its effort to continue to supervise Japan's largest lender after it switched its state branches to federal oversight this week, according to court filings. NEW YORK (Reuters) - Mitsubishi UFJ Financial Group Inc (MUFG) on Wednesday sued New York’s banking regulator to stop its effort to continue to supervise Japan's largest lender after it switched its state branches to federal oversight this week, according to court filings.Q: SQL query different results between workbench and PHP script in the same date range I have a PHP script that helps me to make some financial reports like capital, profits, total sold item, total item in store between 2 dates: $result[] = 0; $res[] = 0; $fetchStat[]=0; if(isset($_POST['generate_capital'])) { $from_d = $_POST['from_d']; $to_d = $_POST['to_d']; $stat = "SELECT sum(sell_quantity(sell_price-init_price)) AS 'rebeh', sum(init_price(quantity-sell_quantity)) AS 'capital', sum(sell_pricesell_quantity) AS 'profits', sum(quantity) AS 'total_item', sum(sell_quantity) AS 'total_sell' FROM purchases WHERE date_now BETWEEN :d1 AND :d2"; $stmtStat = $conn->prepare($stat); $stmtStat->bindValue(':d1', $from_d); $stmtStat->bindValue(':d2', $to_d); $execStat = $stmtStat->execute(); $fetchStat= $stmtStat->fetchAll(); } Now, the same query in MySQL workbench will give me a specific result: SELECT sum(sell_quantity(sell_price-init_price)) AS 'rebeh', sum(init_price(quantity-sell_quantity)) AS 'capital', sum(sell_pricesell_quantity) AS 'profits', sum(quantity) AS 'total_item', sum(sell_quantity) AS 'total_sell' FROM purchases WHERE date_now BETWEEN '2016-02-02' AND '2016-05-09' The result is: And the same query in the PHP script with the same date range will give me other values: I've changed the Arabic keywords with English ones so you can see the difference. Any help is appreciated. EDIT: Adding var_dump result for 2 dates A: As it stands, it appears that the most likely cause is that your date formats have the month and day in the wrong order, for the 2nd of February, that doesn't matter, but for the 9th of May, it would become the 5th of September. Now, the reason that the data for the 9th of May isn't included when you run the query directly is because a date is actually midnight on that date, making it exclusive of that date when it comes at the end of a between. It's possible there is something else, so if this doesn't work, try echoing out all your values at every point, until you know exactly what is being run, and it should become clear. To clarify, when using '/' in a date, MySQL uses the following format: '%d/%m/%Y' Which would explain why it works if you enter a string into your text box. Information Land of Common Sense (2017) Summary Sang Shik is described as a “wacko secretary” who dreams of being a top diplomat: Good-looking, athletic, and a competent fighter, he is described as “halfway between Jang Geu Rae [of Misaeng] and [spy comedy] Kingsman.” Nara, meanwhile, is a diplomat with strict principles who never does things by half-measures and doesn’t know how to hide even the smallest emotion, who’s described as halfway between the perfect diplomat and a nutjob--- Name: mirtop URL: https://github.com/miRTop/mirtop Description: Command line tool to annotate miRNAs with a standard mirna/isomir naming --- This tool is dedicated to the creation and management of miRNA alignment output using the standardized GFF3 format (https://github.com/miRTop/mirGFF3). A unified miRNA alignment format allows to easily compare the output of different alignement tools. Currently, mirtop can convert into mirGFF3 the outputs of commonly used pipelines, such as seqbuster, isomiR-SEA, sRNAbench, Prost! as well as BAM files. Best Most Stylish Reclining Couches 2017 By adminPosted on August 16, 2017November 11, 2017Best Most Stylish Reclining Couches 2017 February 2018 Reclining Couches – This The Most Stylish Reclining Couches 2017 photos was upload on August, 16 2017 by admin. Here latest Reclining Couches photos collection. Download other ideas about Reclining Couches in our other blog. Click on wallpapers to get The Most Stylish Reclining Couches 2017 in high resolution.Power Math for Power Circuits How Maple’s 3D capabilities helped solve the mystery of gate resistance on shoot through Desktop Engineering, October 2006 Alan Elbanhawy, a director at Fairchild Semiconductor International, examined the effects of lumped and distributed gate resistance on the phenomenon of shoot through (also known as cross conduction) in synchronous buck. He concludes: “Using Maple allowed us to investigate the interaction of all the important parameters in 3D representations that helped us understand the extent of the interdependencies. The 3D capability offers a very powerful visualization tool of the complete results. To achieve the same results using any other numerical simulation environment requires enormous amount of batch simulation, data compiling, and graphing.”Recurrent bacterial meningitis and impaired host defences. Recurrent pyogenic meningitis is uncommon. Its aetiology is often associated with impaired host defence mechanisms. Two such examples are discussed. Case 1 resulted from an anatomical defect and Case 2 a defect of the complement system.Q: Displaying Contents of an ArrayList that contains objects of another class with private fields How do I print the album title from the array-list if the contents of the object is in a private field in another class? Display Method public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { System.out.println(AlbumList.get(i)); } } Album Class that has private variables title and price. class Album { private String title; private double price; Album(String title, double price) { this.title = title; this.price = price; } public String getTitle() { return this.title; } public double getPrice() { return this.price; } } Cart Class adds songs to arraylist can also get total import java.util.*; public class Cart { List<Album> AlbumList = new ArrayList<Album>(); Main Method putting albums into addAlbum method public static void main(String[] args) { Cart cart1 = new Cart(); Album album1 = new Album("ye", 20); Album album2 = new Album("MBDTF", 16); cart1.addAlbum(album1); cart1.addAlbum(album2); System.out.println(cart1.getTotalAlbums()); cart1.displayAllAlbums(); } adding album to the arralist public void addAlbum(Album album) { AlbumList.add(album); } Unsure on how to display the album public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { System.out.println(AlbumList.get(i)); } } A: Do this. public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { Album album = AlbumList.get(i) System.out.println(album.getTitle() + " "+ album.getPrice()); } } Your Arraylist's objects are actually Album object. So when are accessing an ArrayList object via AlbumList.get(i) command, you're getting an Album object instance. So you pass it on to Album variable. Then access the private field via getter methods you've set up earlier! Cheers! Icon has Black Background It took me a while to just get the MailScanner link to show up, I had to even get WayToTheWeb to help me out with it! But now I've gotten the link to show and after having trouble getting the icon to show... its showing a black background! Anybody know whats up with it? I have tried to upload .jpg, .png, .gif versions. Redid the icon and made a static white background. I've done it all... I think. Anybody have
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1361, 281, 1614, 1066, 253, 15487, 20468, 313, 338, 352, 10654, 598, 582, 604, 368, 457, 250, 2104, 281, 15, 187, 187, 22529, 5566, 32598, 11055, 960, 187, 9586, 604, 368, 1053, 457, 85, 897, 32598, 4095, 13, 816, 1907, 32598, 10564, 476, 12657, 634, 9378, 15, 2896, 40806, 745, 32598, 13, 368, 476, 6379, 253, 7372, 326, 352, 12516, 327, 634 ]	b) The concentration profile of fenofibric acid in the brain.](PPAR2014-753587.005){#fig5} ###### The input parameters used during the simulation of plasma concentrations versus time profiles of fenofibric acid in rat model. Sr. number Input data Value ------------ ------------------------------------------- ------------------------ 1 MW 262.5 2 log⁡P 4.01 3 pK ~a~ (acidic) 3.56 4 Dose 27 mg/kg 5 Lower limit reference solubility (pH 7.4) 0.0294 mg/mL 6 Diffusion coefficient 0.825 × 10^−5^ cm^2^/s 7 Particle density 1.2 g/mL 8 Effective particle radius 5 µm 9 Effective permeability 7.66 × 10^−4^ cm/s 10 Physiology Fasted conditions 11 Absorption model Opt logD Model SA/V 12 Stomach transit time 0.1 h 13 Body weight 0.25 kg (Rat) 14 Clearance 1.1 mL/min/kg 15 Simulation time 36 h ###### The comparison of predicted and in vivo pharmacokinetic parameters of fenofibric acid. Sr. number Pharmacokinetic parameters In vivo Predicted Predicted/in vivo ratio ------------ ---------------------------- ---------------- ----------- ------------------------------- 1 AUC~0--t~ (µg h/mL) 274.68 ± 38.11 271.89 0.99 2 C ~max⁡~ (µg/mL) 20.49 ± 2.32 17.58 0.86 3 T ~max⁡~ (hours) 3.77 ± 0.64 3 0.80 4 f ~2~ Value 67.37 [^1]: Academic Editor: Constantinos Giaginis New 2019 Coachmen RV Clipper Ultra-Lite 16RBD This Clipper Ultra-Lite expandable 16RBD features front and rear expanding beds, and all the amenities you need to enjoy camping with family and friends. Step inside and see how much space you will have to enjoy with the rear expanding bed that is 54" x 74". Straight ahead there is a convenient bath which includes an angled shower, a toilet, and vanity with sink, plus overhead medicine cabinet. There is a kitchenette to your right as you enter featuring a two burner range, single sink, and storage overhead. A food pantry can be found opposite along side of the refrigerator with TV countertop above. In the front along the roadside find a dinette to enjoy your meals at, plus there is more seating opposite with a lounge including overhead storage. Both of these seating areas can easily become sleeping space if needed for family or extra guests. Also in front you will find an expanding bed that is 48" x 74". The expanding bed allows you to have the sleeping space you need without increasing your overall tow length. All this and more makes this a great camper for your family to enjoy! Options: BED END FAN LIGHT CLIPPER GRAPHICS DELUXE PKG FRONT WINDOW W/ ROCK GUARD RVIA SECOND BED END FAN LIGHT TOWABLE ESSENTIALS PKG TRAVEL EASY ROADSIDE ASSISTANCE What Our Customers Are Saying You will get my business always! Dear Mr. Beckley, I want to thank you and your entire staff for running a 1st class RV Dealership. As a fleet manager for Diamond Int. & Nabisco for 11 years in logging, trucking, and cookie delivery with combined fleets of 3,800 units on the road, when I find a quality organization A++ rated in my book, it is worthy of praise I met your sales team 6 years ago, so when I needed service on my Crossroads ... More » - Peter from Rock Hall, MD Rates and amount financed are determined by credit history. Your actual payments may vary. Plus tax, title and license. See dealer for details. Get Our Lowest Price Krazy Kelly's prices are so low, {mfg} won't allow us to display our price without you requesting it. So, please complete the simple form below to receive Krazy Kelly's Lowest Price! We'll get back with you as soon as possible, during normal business hours. Name Email Phone Zip Do you have a Trade In? Year Make Model# Mileage Amount Desired Tire Condition Last Resealed? Body Damage/Sidewall Delamination? If yes, please describe: Has the unit been smoked in? Leaks/Soft Floor/Soft Wall/Soft Ceiling/Discolored Paneling? If yes, please describe: Appliances in working order? Overall Condition Other Comments: It's ok to contact me about future discounts and events. (Easily unsubscribe at any time.) Coachmen RV is built upon a simple principle … “Dedicated to the enrichment of your life.” By providing you with long term value through all that we do, our focus is on providing a product with superior value and backing it through superior service and support. Once you become a Coachmen owner, we are committed to enhancing your Coachmen RV ownership and lifestyle experience… creating friends for life and memories that will last a lifetime. At Coachmen you will find a rich history of commitment from our Team Members. This commitment extends to our owners and in the pride we have for our brand. The close relationship that we share with our owners and our dealers is a quality that others have been trying to mimic over our 50 year history. Our goals and principles remain well in focus. We do create customers for life www.beckleysrvs.com Beckleys RVs is not responsible for any misprints, typos, or errors found in our website pages. Any price listed excludes sales tax, registration tags, and delivery fees. All prices may not include Beckley’s Camping Center’s 145 point pre-delivery inspection. Manufacturer-provided pictures, specifications and features may be used as needed. Inventory shown may be only a partial listing of the entire inventory. Please contact us at 800-615-6171 for availability as our inventory changes rapidly. All calculated payments are an estimate only and do not constitute a commitment that financing or a specific interest rate or term is available.Tip of the Week: How to Boost your Laptop’s Battery Power We all know the pains of having a laptop with low battery power, but sometimes it feels like you're perpetually plugging in your computer; even when it seems like the battery should last longer. These battery problems are common, but they aren’t an endgame for your laptop. There are several ways you can jumpstart your laptop’s battery. The purpose of a laptop is to remain portable while computing, and that isn’t possible if your battery is continuously failing. You shouldn’t have to be tied to an outlet on a daily basis in order to keep yourself productive. With these five tips, you should be able to keep your laptop alive significantly longer. Windows Updates Can Improve Battery Life If you want your computer to stay protected against the threats present in the online community, the latest patches for your operating system are a necessity. With Windows updates, you only receive these if you are using a supported operating system. Microsoft releases security updates and patches regularly, so you should have no problem maintaining the latest fixes for your operating system. As it turns out, these same updates can improve battery life. MTG can apply updates and patches to your systems remotely and securely, taking the responsibility of keeping your system secure off your shoulders. Optimize Your Power Settings In Windows 8.1, you have several options available to you to change your power settings. You can either choose a preset power plan, or build your own. To access these settings, look for the Power Options selection in the Control Panel. Some of the available options include: Screen brightness. How often the display turns off. When the computer sleeps. Where your computer’s resources are most allocated. Dim the Monitor Display Your laptop has several settings for brightness which can affect how long your battery lasts. Naturally, the higher the brightness on your monitor, the more energy it uses. According to CNet, the brightness of your monitor should be below half, or whatever is most comfortable for your eyes. In Windows 8.1, there is a slider which helps you adjust the brightness to the perfect degree. It can also help to turn down the keyboard brightness (if it lights up), if you’re able to. Turn Off Bluetooth Connections Even if you don’t use Bluetooth devices, just having Bluetooth activated can drain your battery. By shutting off Bluetooth, you can decrease the strain that it puts on your
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281, 16277, 1929, 4343, 283, 4534, 66, 3374, 326, 878, 281, 320, 4307, 562, 15, 733, 7819, 562, 326, 31121, 4852, 327, 247, 11287, 25105, 285, 2550, 2118, 15744, 875, 521, 2586, 285, 2571, 15, 4952, 323, 247, 5006, 665 ]	in a luxury hotel? You'll enjoy your best siesta yet, as well as plenty of spa and pool lounge time. Swissotel Chicago: This location sets the bar for many guest services and amenities offered in downtown Chicago, and it happens to have great views while being located close to shopping mecca the Miracle Mile. On your day of rest, how about you indulge in a little gift-buying? That never hurt anyone! La Pousada de Santa Fe: Located in downtown Santa Fe, this resort and spa puts you conveniently in the center of the action, as well as in the middle of historic Santa Fe charm. This location is just two blocks from art galleries and shopping. The London West Hollywood: Hollywood glamour meets the high-quality expectations of staying at a London location. Always sophisticated, the London West Hollywood combines modern style with Hollywood charm. If personality and luxury are what you require, you've come to the right place. The Winvian: This country spot tops our list of must-visits. This countryside location features stunning surroundings and awesome amenities that just urge you to kick back. Individual designer cottages are warm and inviting, and are planned to captivate plenty of personalities. Monday, September 21, 2009 Moms can get lonely, especially those child-rearing in more rural regions. From busy days where you get run down to days of nothing but routine, everyone needs a shoulder between vacations. CNN featured a special list of "friend types" that every mom should have around, and we don't think it's out of line to suggest that perhaps these friends might consider a vacation with you and your family. Why not? Imagine the benefits you'd reap from having two support systems, plus friends for the kids, while you enjoy a child-friendly resort that's just right for parents with a stressful routine at home. Soak in the pool, hang out at the spa, and zip off to the theatre or museums with your new friends to utilize your luxury hotel's excellent childcare facilities and trustworthy employees. You might not expect to relax so much when you take the kids along with you, but that's part of the fun! Without further ado, here are specific friend types to consider, which can make your life at home and on your vacation so much more enjoyable. Been There, Done That: These friends are just right for the mom in need. When you are feeling stumped about a parenting problem or are stuck on the terrible twos, you have a support system to tell you exactly what you should (and should not) be doing. Isn't it nice not to second-guess yourself for once? I'll Do Anything for You: The ultra-helpful friend who never says no mustn't be taken advantage of, even if she doesn't have kids of her own. She's enthusiastic and ready to take your kids to baseball, soccer, or basketball, or even help with the bake sale preparations. She's a keeper! The Glam Girlfriend: When you're a mom, the looks can be put on the back burner--permanently. Trust this best friend to take you out on the town, bring you new brands, and give you advice on avoiding "mom jeans" forever. Use her for inspiration, advice, and hopefully her wardrobe as well. Brutally Honest Friend: She tells it like it is. . . but shouldn't someone? While it's tough to have a friend like this around, it is nice to have a person on hand to ask for a dose of reality. Between kids' TV, meal-making, working, and planning, perspective can slide a bit. Have your friend jolt you into reality and make you get moving! Did you find a friend who sounds like someone on this list? If not, check out CNN's full friend guide, and then get to planning your vacation with the kids. Fairmont Southampton: This Bermuda location often has family offers that benefit busy families, and they also happen to boast one of the most impressive natural locations that the Caribbean has to offer. An indoor heated pool, spa location, and salon are all you need to spend some time unwinding. Acqualina Resort and Spa: Situated for prime dining and shopping, this resort right on the ocean has multiple children's programs to explore. While you and your new best friend bask in the Florida sun, you can rest assured that they'll be kept entertained and safe as you enjoy multiple ways to relax at the resort. Step one, the pool. Step two, your perfect guest suite. . . The Arrabelle, Vail Square: Take the ski and snowboard-loving teens on a vacation they'll never forget. . . this hotel is perfectly situated at the foot of the slopes in a European-inspired location. Snap plenty of pics of your family at this picturesque spot with first-class amenities and Rock Resort-level perks. Spring Creek Ranch: With close proximity to mountain trails, the Spring Creek Ranch attracts plenty of wildlife. Open yearly, this ranch has a view from every room, and is situated close to national parks just primed for exploring. Be sure to check out their award-winning Wilderness Spa. Saturday, September 19, 2009 The Guinness Book just released a mega-list of all the records broken, and it's surprising just how many new additions popped up in the new version. Why not have a fun and fascinating peek at just a few of the individuals who got the place of honor in the Guinness Book? 1,253 people dressed up like Smurfs in Ireland--the most in a single gathering. A ball of plastic wrap fashioned by an 11-year-old boy from Michigan reached 11 feet across--and got him special recognition as well. Brenden Adams of Washington, who has a 12th chromosome split in half, is 7 feet, 4.6 inches tall, and can't fit into cars. Since he's has knee replacements, he doesn't play basketball, preferring to bike and camp with his friends. 7.12 is the longest tuft of hair ever sprouted from someone's ear, and the honor has gone to Anthony Victor of India. Pushing the boundaries is a fascinating thing, and we can do that with travel, too. Instead of just booking a hotel and going to the city that sounds interesting, be sure to look up some curiosities in each city you visit. It'll really perk up your trip, especially when you take a ton of pics of the fascinating place that's caught your eye! Here are just a few suggestions of must-visit travel curiosities worldwide, and where to stay when you go to visit them: Montreal: St. Joseph's Oratory is a huge basilica located on Queen Mary Road, and its rumored healing powers have resulted in a giant collection of crutches and other memorabilia off the healed. Where to Stay: Try the Hotel Le St. James, which has old-fashioned appeal and modern convenience. Located in the heart of Montreal, it's a good place to stay if you'd like a little romance on your trip--and be close to the convention center as well. Tokyo: Go to a Cat Cafe while in Tokyo. The Curl Up Cafe features happily snoozing kitties on leather couches and chairs--and the 12 felines who hang out here commute with the owner every day. Where to Stay: The Park Hyatt Tokyo is located on the West Shinjuku and happens to be the hotel featured in Lost in Translation. The New York Grill is also one of Tokyo's best restaurants, so be sure to book early if you want to try it out. New York City: While NYC is known for its museums, the Museum of Sex is another experience entirely. Opened in 2002, it's not for the conservative or faint-of-heart, but the curious will get to browse through a collection of ever-changing displays. No one under 18 is permitted. Where to Stay: The Hotel Plaza Athenee in New York is located on the fashionable east side of Manhattan and is located close to Central Park and shopping destinations. You also have a chance to try global cuisine at their stunning eatery. Paris: Pere Lachaise might be a cemetery, but its unusual garden-like layout is the resting place of many a famed poet, artist, and entertainer. While you won't be alone when you make your trek to this location, it's a must-visit for any traveler in Paris.Where to Stay: The Four Seasons Hotel George V seems like you're staying in a fabulously luxurious private home, but you're actually not--the hotel decorators have lavished a great deal of money on these special rooms in a prime location. Thursday, September 17, 2009 Mong Thongdee has caught the world's attention with a story that's worthy of front-page news. The 12-year-old resident of Thailand might have construction worker parents making around $7 per day, but he also placed as the nation's best in a paper plane contest with a dart that floated 12.5 seconds in the air--long enough for him to be invited to represent Thailand in the Japanese origami airplane competition. Think there's a catch? There is, and of the type that we travelers might have temporarily faced while planning a zig-zagging trip to lesser known countries--visa issues that need to be worked out. It turns out that Mong lives on a temporary visa and cannot move freely between his country and others. Even for a boy who
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3214, 63, 19, 64, 90, 362, 46865, 187, 50274, 89, 13, 340, 393, 249, 544, 17, 13, 337, 1092, 5062, 393, 6190, 92, 395, 94, 5062, 85, 393, 249, 544, 17, 13, 337, 20924, 423, 92, 14856, 2138 ]	) and residual neural network (`maps.ResNet`). It is also convenient to choose different training hyperparameters, such as loss types, metrics, optimizers, learning rate schedules, initializations and regularizations. In addition to solving differential equations, DeepXDE can also be used to approximate functions from multi-fidelity data [@meng2019composite], and learn nonlinear operators [@lu2019deeponet]. Customizability --------------- All the components of DeepXDE are loosely coupled, and thus DeepXDE is well-structured and highly configurable. In this subsection, we discuss how to customize DeepXDE to address new problem requirements, e.g., new geometry or network architecture. ### Geometry As we introduced above, DeepXDE has already supported 7 basic geometries and the CSG technique. However, it is still possible that the user needs a new geometry, which cannot be constructed in DeepXDE. In this situation, a new geometry can be defined as shown in Procedure \[code:geometry\]. Currently DeepXDE does not support accurately descriptions of complex curvilinear boundaries; however, a future extension could be incorporation of the non-uniform rational basis spline (NURBS) [@hughes2005isogeometric] for such representations. ``` {.Python linenos=""} class MyGeometry(Geometry): def inside(self, x): """Check if x is inside the geometry.""" def on_boundary(self, x): """Check if x is on the geometry boundary.""" def boundary_normal(self, x): """Compute the unit normal at x for Neumann or Robin boundary conditions.""" def periodic_point(self, x, component): """Compute the periodic image of x for periodic boundary condition.""" def uniform_points(self, n, boundary=True): """Compute the equispaced point locations in the geometry.""" def random_points(self, n, random="pseudo"): """Compute the random point locations in the geometry.""" def uniform_boundary_points(self, n): """Compute the equispaced point locations on the boundary.""" def random_boundary_points(self, n, random="pseudo"): """Compute the random point locations on the boundary.""" ``` ### Neural networks DeepXDE currently supports two neural networks: feed-forward neural network (`maps.FNN`) and residual neural network (`maps.ResNet`). A new network can be added as shown in Procedure \[code:nn\]. ``` {.Python linenos=""} class MyNet(Map): @property def inputs(self): """Return the net inputs.""" @property def outputs(self): """Return the net outputs.""" @property def targets(self): """Return the targets of the net outputs.""" def build(self): """Construct the network.""" ``` ### Callbacks It is usually a good strategy to monitor the training process of the neural network, and then make modifications in real time, e.g., change the learning rate. In DeepXDE, this can be implemented by adding a callback function, and here we only list a few commonly used ones already implemented in DeepXDE: - `ModelCheckpoint`, which saves the model after certain epochs or when a better model is found. - `OperatorPredictor`, which calculates the values of the operator applying on the outputs. - `FirstDerivative`, which calculates the first derivative of the outpus with respect to the inputs. This is a special case of `OperatorPredictor` with the operator being the first derivative. - `MovieDumper`, which dumps the movie of the function during the training progress, and/or the movie of the spectrum of its Fourier transform. It is very convenient to add other `callback` functions, which will be called at different stages of the training process, see Procedure \[code:callback\]. ``` {.Python linenos=""} class MyCallback(Callback): def on_epoch_begin(self): """Called at the beginning of every epoch.""" def on_epoch_end(self): """Called at the end of every epoch.""" ``` Demonstration examples {#sec:example} ====================== In this section, we use PINNs and DeepXDE to solve different problems. In all examples, we use the $\tanh$ as the activation function, and the other hyperparameters are listed in \[tab:hyperparameter\]. The weights $w_f$, $w_b$ and $w_i$ in the loss function are set as 1. The codes of all examples are published in GitHub. Example NN Depth NN Width Optimizer Learning rate \# Iterations --------- ---------- ---------- -------------- --------------- --------------- 1 4 50 Adam, L-BFGS 0.001 50000 2 3 20 Adam, L-BFGS 0.001 15000 3 3 40 Adam 0.001 60000 4 3 20 Adam 0.001 80000 5 4 20 L-BFGS - - : Hyperparameters used for the following 5 examples. “Adam, L-BFGS” represents that we first use Adam for a certain number of iterations, and then switch to L-BFGS. The optimizer L-BFGS does not require learning rate, and the neural network is trained until convergence, so the number of iterations is also ignored for L-BFGS.[]{data-label="tab:hyperparameter"} Poisson equation over an L-shaped domain ---------------------------------------- Consider the following two-dimensional Poisson equation over an L-shaped domain $\Omega = [-1,1]^2\setminus [0,1]^2$: $$\begin{aligned} -\Delta u(x,y) &= 1,\quad (x,y)\in \Omega, \\ u(x,y) &= 0, \quad (x,y)\in \partial \Omega.\end{aligned}$$ We choose 1200 and 120 random points drawn from a uniform distribution as $\mathcal{T}_f$ and $\mathcal{T}_b$, respectively. The PINN solution is given in \[fig:Poisson:Lshape\]B. For comparison, we also present the numerical solution obtained by using the spectral element method (SEM) [@Karbook] (\[fig:Poisson:Lshape\]A). The result of the absolute error is shown in \[fig:Poisson:Lshape\]C. ![Example 4.1. Comparison of the PINN solution with the solution obtained by using spectral element method (SEM). (A) the SEM solution $u_{SEM}$, (B) the PINN solution $u_{NN}$, (C**) the absolute error $\|u_{SEM} - u_{NN}\|$.[]{data-label="fig:Poisson:Lshape"}](Poisson.pdf){width="\textwidth"} RAR for Burgers equation ------------------------ We first consider the 1D Burgers equation: $$\begin{gathered} \frac{\partial u}{\partial t} + u \frac{\partial u}{\partial x} = \nu \frac{\partial^2 u}{\partial x^2}, \quad x\in[-1, 1], ~ t \in[0, 1], \\ u(x, 0) = -\sin(\pi x), \quad u(-1, t) = u(1, t) = 0.\end{gathered}$$ Let $\nu = 0.01/\pi$. Initially, we randomly select 2500 points (spatio-temporal domain) as the residual points, and then 40 more residual points are added adaptively via RAR developed in \[sec:rar\] with $m = 1$ and $\mathcal{E}_0 = 0.005$. We compare the PINN solution with RAR and the PINN solution based on 2540 randomly selected training data (\[fig:burgers\] A and B), and demonstrate that PINN with RAR can capture the discontinuity much better. For a comparison, the finite difference solutions using central difference scheme for space discretization and forward Euler scheme for time discretization for the Burgers equation in the conservative form are also shown in \[fig:burgers\]A. Here, we also present two examples for the residual points added via the RAR method. As shown in \[fig:burgers\] C and D, the added points (green crosses) are quite close to the sharp interface, which indicates the effectiveness of RAR. We further solve the following two-dimensional Burgers equation using the RAR: $$\begin{gathered} \partial_t u + u \partial_x u + v \partial_y u = \frac{1}{\mbox{Re}} (\partial^2_x u + \partial^2_y u),\\ \partial_t v + u \partial_x v + v \partial_y v = \frac{1}{\mbox{Re}} (\partial^2_x v + \partial^2_y v),\\ x, y \in [0, 1], ~ \mbox{and} ~t \in [0, 1],\end{gathered}$$
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1673, 2112, 669, 2733, 8454, 55, 61, 1274, 9, 256, 61, 918, 10, 3572, 5, 253, 2460, 273, 669, 6065, 370, 310, 6507, 15, 187, 187, 1992, 5276, 3512, 818, 13, 1908, 247, 370, 55, 61, 249, 393, 1588, 92, 55, 724, 2112, 342, 49674, 1939, 7529, 4910, 370, 43, 578, 18, 5548, 5589, 1157, 43, 578, 76, 14, 18, 724, 275, 370, 56, 10506, 3932, 669, 2690, 92, 1704, 889, 1274, 9, 187, 61, 2733, 8454, 87, 4799, 5994, 3572, 43, 578, 74, 889, 918, 10, 393, 8275, 470, 5, 285, 669, 2690, 92, 45668, 2026, 76, 889, 5090, 470, 12063 ]	-1.\end{array}\right.$$Then $\mathrm{ct}_{\kappa }$ is an odd function, satisfies $\lim_{t\rightarrow 0^{-}}\mathrm{ct}_{\kappa }=-\infty ,$ and is strictly decreasing on $\left( 0,\infty \right) .$ Let $\Lambda _{N}$ be the Lagrangian family along $\gamma _{v}$ from Equation \[dfn of Lambda\_N\]. Let $S$ be the corresponding Riccati operator. Observe that at $t=0,$ the restriction of $S$ to the second summand in (\[dfn of Lambda\_N\]) coincides with the shape operator $S_{v}$ of $N$. If the conclusion is false, there are $\left\{ J_{1},\ldots ,J_{k}\right\} \subset \Lambda _{N}$ with $\left\{ J_{i}\left( 0\right) \right\} _{i=1}^{k}$ orthonormal so that $$\begin{aligned} J_{i}^{\prime }\left( 0\right) &=&S\left( J_{i}\left( 0\right) \right) \text{ and } \\ \left\vert \Sigma _{i=1}^{k}\left\langle S\left( J_{i}\left( 0\right) \right) ,J_{i}\left( 0\right) \right\rangle \right\vert &\geq &k\cdot \mathrm{ct}_{\kappa }\left( \mathrm{FocalRadius}\left( N\right) -\alpha \right) ,\end{aligned}$$for some $\alpha \in \left( 0,\mathrm{FocalRadius}\left( N\right) \right) .$ After possibly replacing $v$ with $-v$, we may assume that $$\begin{aligned} \Sigma _{i=1}^{k}\left\langle S\left( J_{i}\right) ,J_{i}\right\rangle \|_{0} &\leq &-k\cdot \mathrm{ct}_{\kappa }\left( \mathrm{FocalRadius}\left( N\right) -\alpha \right) \\ &=&k\cdot \mathrm{ct}_{\kappa }\left( \alpha -\mathrm{FocalRadius}\left( N\right) \right) ,\text{ since }\mathrm{ct}_{\kappa }\text{ is an odd function} \\ &<&0.\end{aligned}$$It follows from Lemma \[sing soon Ric\_k Lemma\] that for all $t_{1}\in \left( 0,\mathrm{FocalRadius}\left( N\right) \right) $ there is a $k$–dimensional subspace $W_{t_{1}}\subset \Lambda _{N}$ so that $$\mathrm{Tr}\left( S\|_{W_{t_{1}}}\right) \leq k\cdot \mathrm{ct}_{\kappa }\left( \alpha -\mathrm{FocalRadius}\left( N\right) +t_{1}\right) .$$Since $\alpha -\mathrm{FocalRadius}\left( N\right) <0$ and $\lim_{t\rightarrow 0^{-}}\mathrm{ct}_{\kappa }=-\infty ,$ $\Lambda _{N}$ has a singularity by time $\mathrm{FocalRadius}\left( N\right) -\alpha .$ This is a contradiction because $\Lambda _{N}$ is nonsingular on the interval $\left( 0,\mathrm{FocalRadius}\left( N\right) \right) $. Let $M$ be a complete Riemannian $n$–manifold with $Ric_{k}$ $\geq 0,$ and let $N$ be any closed submanifold of $M$ with $\dim \left( N\right) \geq k$ and infinite focal radius. Let $v$ be any unit normal vector to $N.$ As in Equation \[dfn of Lambda\_N\] we let$$\Lambda _{N}\equiv \left\{ J\|J\left( 0\right) =0\text{, }J^{\prime }\left( 0\right) \in \nu _{\gamma _{v}\left( 0\right) }\left( N\right) \right\} \oplus \left\{ J\|J\left( 0\right) \in T_{\gamma _{v}\left( 0\right) }N\text{ and }J^{\prime }\left( 0\right) =\mathrm{S}_{v}J\left( 0\right) \right\} .$$We set$$\begin{aligned} \mathcal{V} &\equiv &\left\{ J\|J\left( 0\right) =0\text{, }J^{\prime }\left( 0\right) \in \nu _{\gamma _{v}\left( 0\right) }\left( N\right) \right\} \text{, and } \\ W &\equiv &\left\{ J\|J\left( 0\right) \in T_{\gamma _{v}\left( 0\right) }N\text{ and }J^{\prime }\left( 0\right) =\mathrm{S}_{v}J\left( 0\right) \right\} .\end{aligned}$$ Since $N$ has no focal points, $\Lambda _{N}$ has no singularities on $\mathbb{R}\setminus \left\{ 0\right\} $. Thus for all $J\in \Lambda _{N}\setminus \left\{ 0\right\} $ and all $t\in \mathbb{R}\setminus \left\{ 0\right\} ,$ $J\left( t\right) \neq 0.$ By replacing $v$ with $-v$, if necessary, we may assume that $$\mathrm{Tr}\left( \mathrm{S}\|_{W}\left( 0\right) \right) \leq 0. \label{inti nonpos}$$ By Part 3 of Lemma \[sing soon Ric\_k Lemma\], it follows that $t\longmapsto \Lambda \left( t\right) $ splits orthogonally into the parallel distributions $$\Lambda \left( t\right) \equiv W\left( t\right) \oplus \mathcal{V}\left( t\right) ,$$and every field in $W$ is parallel. Since we started with an arbitrary normal vector$,$ $N$ is totally geodesic, and Parts 1 and 4 are proven. Part 2 is a consequence of the Hopf-Rinow Theorem (see Part e of Theorem 2.8 on page 147 of [@doCarm]). Part 3 follows by observing that $\exp _{N}^{\perp }:\left( \nu \left( N\right) ,\left( \exp _{N}^{\perp }\right) ^{\ast }\left( g\right) \right) \longrightarrow \left( M,g\right) $ is a local isometry, so as in the proof of Cartan-Hadamard, $\exp _{N}^{\perp }$ is a cover (see Lemma 3.3 on page 150 of [@doCarm] or Lemma 5.6.4 of [@Pet]). Part 5 follows from the fact that every field in $W$ is parallel. To prove Part 6, let $\mathrm{II}$ be the second fundamental form of $\mathrm{image}\left( \Phi \right) .$ Since $$\gamma _{V\left( s\right) }:t\longmapsto \Phi \left( t,s\right) =\exp _{c\left( s\right) }^{\perp }\left( tV\left( s\right) \right)$$is a geodesic, $\mathrm{II}\left( \frac{\partial \Phi }{\partial t},\frac{\partial \Phi }{\partial t}\right) =0,$ and since $\frac{\partial \Phi }{\partial s}$ is parallel along $\gamma _{V\left( s\right) },$ $\mathrm{II}\left( \frac{\partial \Phi }{\partial t},\frac{\partial \Phi }{\partial s}\right) =0.$ To determine $\mathrm{II}\left( \frac{\partial \Phi }{\partial s},\frac{\partial \Phi }{\partial s}\right) ,$ observe that the lift, $\left( \exp _{N}^{\perp }\right) ^{\ast }\left( \frac{\partial \Phi }{\partial s}\right) ,$ of $\frac{\partial \Phi }{\partial s}$ via $\exp _{N}^{\perp },$ is a basic horizontal, geodesic field for the Riemannian submersion$$\pi :\left( \nu \left( N\right) ,\left( \exp _{N}^{\perp }\right) ^{\ast }\left( g\right) \right) \longrightarrow N.$$Thus $\mathrm{II}\left( \frac{\partial \Phi }{\partial s},\frac{\partial \Phi }{\partial s}\right) =\nabla _{\frac{\partial \Phi }{\partial s}}\frac{\partial \Phi }{\partial s}\equiv 0,$ and the image of $\Phi $ is totally geodesic. Since $\frac{\partial \Phi }{\partial s}$ is a parallel Jacobi field along $\gamma _{V\left( s\right) },$ the image of $\Phi $ is flat. To prove Part 7, consider a $V\in \mathcal{V}$ along with orthonormal parallel fields $J_{1},\ldots ,J_{k-1}$ in $W.$ Since $\mathrm{sec}\left( \gamma _{v}^{\prime },J_{i}\right) \equiv 0$ and $\mathrm{Ric}_{k}\geq 0,$
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281, 9413, 670, 436, 5389, 10325, 15, 3166, 368, 2868, 275, 43630, 6978, 265, 32, 390, 310, 816, 247, 33010, 14, 33223, 2181, 32, 187, 187, 24099, 1722, 13, 4765, 13, 337, 27, 1812, 12920, 187, 187, 23450, 790, 265, 313, 2055, 10, 187, 187, 1552, 9400, 556, 816, 644, 2849, 1245, 407, 14759, 285, 643, 2067, 5098, 533, 556, 417, 644, 11464, 15, 4952, 253, 2806, 7793, 11210, 626, 644, 4232, 15, 1292, 604, 2455 ]	www.brainwy.com/tracker/PyDev/645 # if __pydevd_id__ is None, recalculate it... also, use an heuristic # that gives us always the same id for the thread (using thread.ident or id(thread)). raise AttributeError() except AttributeError: tid = _get_or_compute_thread_id_with_lock(thread, is_current_thread=True) return tid def get_thread_id(thread): try: # Fast path without getting lock. tid = thread.__pydevd_id__ if tid is None: # Fix for https://www.brainwy.com/tracker/PyDev/645 # if __pydevd_id__ is None, recalculate it... also, use an heuristic # that gives us always the same id for the thread (using thread.ident or id(thread)). raise AttributeError() except AttributeError: tid = _get_or_compute_thread_id_with_lock(thread, is_current_thread=False) return tid def set_thread_id(thread, thread_id): with _thread_id_lock: thread.__pydevd_id__ = thread_id #======================================================================================================================= # Null #======================================================================================================================= class Null: """ Gotten from: http://aspn.activestate.com/ASPN/Cookbook/Python/Recipe/68205 """ def __init__(self, args, kwargs): return None def __call__(self, args, *kwargs): return self def __enter__(self, args, *kwargs): return self def __exit__(self, args, *kwargs): return self def __getattr__(self, mname): if len(mname) > 4 and mname[:2] == '__' and mname[-2:] == '__': # Don't pretend to implement special method names. raise AttributeError(mname) return self def __setattr__(self, name, value): return self def __delattr__(self, name): return self def __repr__(self): return "<Null>" def __str__(self): return "Null" def __len__(self): return 0 def __getitem__(self): return self def __setitem__(self, args, *kwargs): pass def write(self, args, *kwargs): pass def __nonzero__(self): return 0 def __iter__(self): return iter(()) # Default instance NULL = Null() def call_only_once(func): ''' To be used as a decorator @call_only_once def func(): print 'Calling func only this time' Actually, in PyDev it must be called as: func = call_only_once(func) to support older versions of Python. ''' def new_func(args, *kwargs): if not new_func._called: new_func._called = True return func(args, **kwargs) new_func._called = False return new_func # Protocol where each line is a new message (text is quoted to prevent new lines). # payload is xml QUOTED_LINE_PROTOCOL = 'quoted-line' ARGUMENT_QUOTED_LINE_PROTOCOL = 'protocol-quoted-line' # Uses http protocol to provide a new message. # i.e.: Content-Length:xxx\r\n\r\npayload # payload is xml HTTP_PROTOCOL = 'http' ARGUMENT_HTTP_PROTOCOL = 'protocol-http' # Message is sent without any header. # payload is json JSON_PROTOCOL = 'json' ARGUMENT_JSON_PROTOCOL = 'json-dap' # Same header as the HTTP_PROTOCOL # payload is json HTTP_JSON_PROTOCOL = 'http_json' ARGUMENT_HTTP_JSON_PROTOCOL = 'json-dap-http' ARGUMENT_PPID = 'ppid' class _GlobalSettings: protocol = QUOTED_LINE_PROTOCOL def set_protocol(protocol): expected = (HTTP_PROTOCOL, QUOTED_LINE_PROTOCOL, JSON_PROTOCOL, HTTP_JSON_PROTOCOL) assert protocol in expected, 'Protocol (%s) should be one of: %s' % ( protocol, expected) _GlobalSettings.protocol = protocol def get_protocol(): return _GlobalSettings.protocol def is_json_protocol(): return _GlobalSettings.protocol in (JSON_PROTOCOL, HTTP_JSON_PROTOCOL) class GlobalDebuggerHolder: ''' Holder for the global debugger. ''' global_dbg = None # Note: don't rename (the name is used in our attach to process) def get_global_debugger(): return GlobalDebuggerHolder.global_dbg GetGlobalDebugger = get_global_debugger # Backward-compatibility def set_global_debugger(dbg): GlobalDebuggerHolder.global_dbg = dbg if __name__ == '__main__': if Null(): sys.stdout.write('here\n') Association of ER-alpha gene polymorphism with metabolic phenotypes in Chinese Hans. Recently, two polymorphisms (rs1884052 and rs3778099) of estrogen receptor alpha (ER-alpha) gene were identified as being associated with primary quantitative bone mineral density (BMD) in a genome-wide association (GWA) study in Framingham cohorts. In this study we aimed at investigating the association of rs1884052 and rs3778099, and another polymorphism (rs2234693) located at intron 1 of the ER-alpha gene with BMD, body mass index (BMI), glucose, triglyceride, and total cholesterol (CHO) levels in Chinese Hans. We recruited 425 consecutive adult volunteers who had a physical examination in the Jinan Maternity and Child Care Hospital. We did not observe significant association of rs1884052 and rs3778099 with BMD, BMI, glucose, triglyceride, and total cholesterol (CHO) levels. For rs2234693, increased levels of BMD for hip, spine or whole-body regions were consistently observed in TT/TC genotype carriers than in CC genotype carriers, although the board line significance diminished after adjusting for age and gender. However, significant association of rs2234693 with glucose and CHO levels were observed in our sample. Subjects with TC/CC genotypes were associated with an increased level of glucose (p = 0.013) and CHO (p = 0.032) levels than subjects with TT genotypes. In conclusion, we did not confirm the association of rs1884052 and rs3778099 with BMD originally discovered in a GWA study; however, we made novel discoveries that rs2234693 was associated with glucose and CHO levels in Chinese Hans.Matt Forte exits early with knee injury; will not return Bears running back Matt Forte has left Sunday’s game against the Chiefs because of a right knee injury. Forte was injured on a run deep in Chicago territory midway through the first quarter, when Kansas City’s Derrick Johnson hit him in the knee. He stayed on the ground for several minutes as medical personnel tended to him. The league’s third-leading rusher walked off the field on his own power and stayed on the sideline for a few minutes before heading to the locker room.Do you think there can be parallel universes? The parallels universes have been a controversial topic for many years there are many physics theories established by big minds like Albert Einstein with his string theory were pose a possibility of other parallels dimensions. There are many investigations about this topic and also in the world of art and cinema, we can see many examples of it like Stranger things, The Chronicles of Narnia, Doom etc. These parallels universes can be explained by the paradox of Schrödinger, It describes that the life of a cat depends on a particle, if the particle disintegrates the cat dies but if the particle does not disintegrate the cat will remain alive. that means that maybe in this world you are a veterinary but in another world you are a carpenter, because you did not have the same chance in both universes, and small variations can create another new reality.I think that we have still had a lot of things to discover about this beautiful universe. Do you believe in parallels universes? or is just a sci-fiction thing? February 17, 2018, 1:36 pm Responses (88) This topic has just been magnified by Hollywood and other several books but has not been proven. Even the black hole hasn't been established. But if ever
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313, 783, 686, 17736, 8539, 1422, 778, 417, 897, 436, 1873, 3707, 275, 187, 475, 10276, 342, 253, 4637, 15, 380, 3570, 7169, 281, 368, 762, 253, 4637, 187, 475, 778, 417, 320, 908, 281, 2794, 13, 390, 8046, 253, 8869, 390 ]	if what ever happens is as you expected it to. By exploring the functionality you probably execute existing test cases (happy path) but you will also test paths not covered in test cases (perhaps resulting in new (automated) test cases to be executed). The more you know about the product that is developed and the more you are experienced with testing, the better the result of the exploratory test. Is exploratory testing only for testers? From my perspective I would say: No, not totally! Perhaps a exploratory test is at best when executed by a tester since our testing skills and mindset would help when testing. But like I mentioned before: The more you know about the product that is developed…. That would indicate that everyone from developers to consultants could be involved in exploratory testing. Not only testers have knowledge about the product developed. For example: Consultants usually know how one or more customers use the product. This knowledge can be of great value when they are testing. Not all developers and tester will have this knowledge. Developers for example know how they developed the product and where to find “weak” spots in the application. They can point them out for you to test, but can also test these themselves, learn, fix bugs and deliver a better (part of the) product. Developers can also practice exploratory testing when doing a code review. Besides literally only reviewing the code, click trough the component if possible and look for some simple bugs. By saying that I’m not saying that testers are obsolete, I think testers just shouldn’t be bothered with finding bugs that are blocking the flow just after two mouse clicks. Why exploratory testing is so important: Following test scripts is repetitive work, testing a new release for the second time by following a testscript will probably not give you new results. It’s most unlikely that these test will now suddenly fail. By exploring (parts of) the system under test you will probably find new results, find new testcases, write them down and perhaps automate them. The first thing I do when I’m done with testing a new version of our application via a manual regression testscript is exploratory testing. This can also be done when your in an agile team and the user store is completed because it reached its definition of done, after that there is nothing holding you back to explore the functionality and put it to done when you as tester are completely satisfied with the result. How to overcome some of the downsides of Exploratory testing Unfortunately exploratory testing also has some downsides. The main problem I experienced was that you can get easily lost in time when exploratory testing, you’ll have to watch out that it down not result in some kind of exhaustive testing. Best practice for me is to time box each exploratory testing session. For each time frame I pick one or two (when testing interaction) particular parts of the system under test, set some objectives what to test, write down or log my findings and when the time is up I move on to the next test. An easy and lightweight tool to help you with creating sessions for exploratory testing is Sessiontester. As described by their website: “It has a timer so you limit your test sessions to a particular length, and it provides an easy way to record session notes.” When to apply exploratory testing Here is a summary of situations in which you could prefer applying exploratory testing: When testing with test scripts is completed but you do not feel totally confidant with the delivered functionality. When fast feedback about a functionality is needed. When the functionality is already mature and no or minor changes has been made. When there is no time to execute a (scripted) functional test but feedback is still required. When testing the frontend of a webapplication with multiple browsers (Internet explorer, Firefox, Safari etc.).CLD-290 NOT PRECEDENTIAL UNITED STATES COURT OF APPEALS FOR THE THIRD CIRCUIT ___________ No. 14-1741 ___________ IN RE: ALTON D. BROWN, Petitioner ____________________________________ On a Petition for Writ of Mandamus from the United States District Court for the Eastern District of Pennsylvania (Related to E.D. Pa. Civ. No. 2-07-cv-03771) ____________________________________ Submitted Pursuant to Rule 21, Fed. R. App. P. June 26, 2014 Before: FUENTES, JORDAN and SHWARTZ, Circuit Judges (Opinion filed: July 2, 2014) _________ OPINION _________ PER CURIAM Pro se litigant Alton Brown has filed a petition for a writ of mandamus, requesting that we order the District Judge to recuse. For the reasons set forth below, we will deny the petition. Brown filed the underlying case in September 2007, and it has developed a protracted history. With respect to the particular petition at bar, Brown alleges that the District Judge is involved in a wide-ranging conspiracy with lawyers, corrections officials, and other judges “to deny him due process and equal protection of the laws.” He also claims more generally that the District Judge is biased and prejudiced against him. Brown filed a motion for recusal in February 2014, which the District Court denied. He relies on 28 U.S.C. § 455 to support this petition for a writ of mandamus.1 Mandamus is a drastic remedy that is available only in extraordinary situations. See Kerr v. U.S. Dist. Court, 426 U.S. 394, 402 (1976). To qualify for this exceptional relief, a petitioner must prove that his right to issuance of the writ is clear and indisputable. See id. at 403. Brown falls far short of this high bar. Brown’s petition implicates two related subsections of § 455, the statute concerning recusal: subsection (a) requires recusal when a judge’s impartiality might reasonably be questioned, and subsection (b) requires recusal when the judge has a personal bias or prejudice concerning a party. Most of the acts Brown cites to demonstrate the District Judge’s alleged conspiracy and bias — denying him leave to amend or supplement his complaint, appointing him counsel, and managing discovery, for instance — are examples of prototypical judicial decision making. And mere dissatisfaction with those rulings does not warrant recusal. See Securacomm Consulting, Inc. v. Securacom Inc., 224 F.3d 273, 278 (3d Cir. 2000) (“We have repeatedly stated that a party’s displeasure with legal rulings does not form an adequate basis for recusal.”). Brown also claims that the District Judge was hostile to him, remarking that he was wasting valuable court resources during discovery proceedings. But even were 1 He also purports to bring the petition pursuant to 28 U.S.C. § 144. But mandamus relief is not available here under § 144, because Brown may still take an appeal from the order denying recusal after final judgment is entered. See In re Sch. Asbestos Litig., 977 F.2d 764, 774-76 (3d Cir. 1992). 2 this comment made in the most impatient of tones, it would not establish bias sufficient to mandate recusal. See Liteky v. United States, 510 U.S. 540, 555-56 (1994) (“Not establishing bias or partiality, however, are expressions of impatience, dissatisfaction, annoyance, and even anger, that are within the bounds of what imperfect men and women . . . sometimes display.). Brown also seems to suggest that the District Judge must recuse because she is a defendant in one of his several active lawsuits against judges, lawyers, and corrections officials. Again, it is well-established that such a situation does not independently warrant recusal. See Azubuko v. Royal, 443 F.3d 302, 304 (3d Cir. 2006); In re Taylor, 417 F.3d 649, 652-53 (7th Cir. 2005). Lastly, conclusory allegations of conspiracy make up the balance of Brown’s petition, but recusal is not required on the basis of “unsupported, irrational, or highly tenuous speculation.” In re United States, 666 F.2d 690, 694 (1st Cir. 1981). Because Brown has not shown that § 455 mandates the District Judge’s recusal, he has failed to establish a clear and indisputable right to the mandamus relief he seeks. His petition is denied. 3 /* * Copyright (c) 2011 Apple Inc. All rights reserved. * * @APPLE_OSREFERENCE_LICENSE_HEADER_START@ * * This file contains Original Code and/or Modifications of Original Code * as defined in and that are subject to the Apple Public Source License * Version 2.0 (the 'License'). You may not use this file except in * compliance with the License. The rights granted to you under the License * may not be used to create, or enable the creation or
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The club had to wait until 1970 for another promotion, when they were promoted as Liga Alef champions. They narrowly avoided relegation in the 1970–71 season, finishing above relegated Maccabi Petah Tikva on goal difference. However, they were relegated the following season after finishing bottom. This time they bounced back immediately as Liga Alef runners-up, and finished 13th in 1973–74, a single point above the relegation zone. Although 1974–75 saw the club finish in their highest-ever position, 7th, they were relegated the following season. The club made a second immediate return to the top flight as Liga Artzit (the new second division) champions, but were relegated again in 1979, marking their last appearance to date in the top division. In 1986 and 1989 the club won the Liga Artzit Toto Cup. In 1994 they were deducted 12 points after being found guilty of match-fixing in a league game against Hakoah Ramat Gan. They were relegated to the third tier in 1997, and following league restructuring in 1999, sank into the fourth division. They were relegated again to Liga Bet in 2003. In 2006, All the football clubs from Hadera merged into one club called Hapoel Ironi Eran Hadera, and at the end of the 2007–08 season the club won the South A division of Liga Bet and were promoted back to Liga Alef. In the 2009–10 season, the club battled for promotion to Liga Leumit and was leading 70% of the season at 1st place. However, they did not achieved promotion after finished 3rd place at Liga Alef South division. in next season of 2010–11 they changed division to the North, and it was a beginning of bad financial problem, and with small budget they needed to build the club from the beginning. at that season, the manager was Ami Elhadad, one of the players who played for the club in the 1970s. at the end of the season they finished in the 8th place. The 2011–12 season was one of their worst seasons, as they finished in the 14th place and had to play-off against Ihud Bnei Maksur from Liga bet. Hadera won the relegation play-off 2–1 after goals scored by Momo Nistel and Elias Zana. during the season, the club saw changes in the manager position, when Ami Elhadad resigned from the club, and replaced by the youth manager, Yohanan Israelov, who did not finish the season as well, as Itzik Ben Tora managed the club in the last two games. . In the 2012–13 season, Eyal Amar, former player for the club, took over the manager position, after three seasons as the manager of local rivals, F.C. Givat Olga. the club started the season well, when showed good games. However, at the end of season they finished in the 7th place. manager Eyal Amar left the club and returned to Givat Olga. In the 2013–14 season, the club was managed by Ahmed Wahab as manager and Yosef Mogiliovsky as assistant-manager, and placed 8th after the first round of the league (15 games). After Ahmed Wahab left the club with his son, Barkat, due to financial problems, and Kobi Badash left for Hapoel Migdal HaEmek, Hadera signed new manager, Ron Keler, which trained the youth section of the club, and finished the season in the 7th place, 6 points short of the promotion play-offs. In The 2014–15 season the started with Gil Fishel as new manager. but after 10 games the manager resign because of financial problems. and after that Sasha Feldman who was a player of the club take care of coaching team. after 4 games he left the club and in the derby with MS Givat olga Itsik Ben Tora stand on the line 1 match. than Yohanan Izraelov return to training the team he was coaching only 5 games and left too. Ron Keller who trained last season take care the club and made a success with team and reach 9th place at Liga alef north. and was the first to win derby in last match 1–0 on Givat Olga. In season 2015–16 was talking to take new management of the team but the talks didn't bring anything and Yoav Kobi still the owner of the club. The team signed new coach past player Momo Nistel that trained before Beitar Pardes Hana with success. In season 2016–17 was big day in the club. The team promote to Liga Leumit the second tier in Israel. after finishing 1st place in the league. It was first time after 20 seens it was the last time to play in second tier. In season 2017–18, the club was promoted again to the Israeli Premier League for the first time after 40 years from the second place of Liga Leumit. In the next season, Hapoel Hadera made a big sensation in the Premier League and secured the place in the championship playoff, what brought the club to improve their previous record in the First Division, seventh place, and finish the season in the sixth place. Current squad As to 6 February 2020 Honours League Cup competitions References 50 Years of Sports and More in Hadera, Efraim Frank (Israel), 2004, pp. 190–227 External links Official Site Hapoel Hadera Eran Israel Football Association Category:Football clubs in Israel Category:Sport in Hadera Hadera Category:Association football clubs established in 1949 Category:1949 establishments in IsraelQ: Drawing lines between arbitrary words on a page I try to get rid of tree-dvips and look for a way to do the following: Circle an arbitrary word on the page and draw an arrow from some other position at the page towards this circled word. In tree-dvips one can just simply declare a word a node and then use connection directives. I guess this can be done with pgf somehow, but the nodes seem to require a position in a coordinate system. This is the tree-dvips code: \documentclass{scrbook} \usepackage{tree-dvips} \begin{document} \begin{tabular}{lllllll} \node{bazas}{bāz-a\v{s}} & agar & mi-xāh-i & fardâ & \node{blk1}{} & bo-kon-i\\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' {\makedash{1pt} \nodeoval{bazas} \abarnodeconnect[-18pt]{blk1}{bazas}} \end{document} A: run it with xelatex \documentclass{scrbook} \usepackage{fontspec} \usepackage{pst-node} \begin{document} \begin{tabular}{lllllll} \ovalnode[linestyle=dashed]{bazas}{bāz-a\v{s}} & agar & mi-xāh-i & fardâ & \rnode{blk1}{~} & bo-kon-i\\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' \ncbar[linestyle=dashed,arrows=->,angle=-90,arm=20pt]{blk1}{bazas} \end{document} A: Addition: A solution with tikz: \documentclass{scrbook} \usepackage{tikz} \usetikzlibrary{shapes.geometric} \begin{document} \begin{tabular}{lllllll} \tikz[remember picture,baseline]\node[anchor=base,ellipse,draw](bazas){baz-a\v{s}}; & agar & mi-xah-i & fardâ % & \node{blk1}{} & \tikz[remember picture,overlay] \draw[->,dashed] (0,0) -- ++(0pt,-4.75ex) coordinate(tmp1) -- (bazas \|- tmp1) -- (bazas \|- tmp1) -- (bazas); & bo-kon-i \\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' \end{document} Science
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]	84\<.012.170.50--9.360.300.880.65--1.190.41Education Primary\-\-\-\-\-\-\-\-\-\-\-- Secondary0.750.54--1.020.070.730.52--1.010.064.830.71--32.940.110.760.56--1.050.09 Tertiary1.120.73--1.710.601.180.76--1.830.471.310.17--10.400.790.970.63--1.480.88Housing Living at home^a^\-\-\-\-\-\-\-\-\-\-\-- Living at home^b^1.601.01--2.530.041.701.04--2.780.041.440.30--6.900.651.721.08--2.740.02 Assisted living0.710.38--1.310.270.900.47--1.710.75\<.01\<.0010.960.610.33--1.130.12 Care home0.680.37--1.240.210.780.39--1.570.480.080.01--0.48\<.010.510.28--0.930.03Use of Analgesics^c^2.171.48--3.16\<.012.131.42--3.18\<.012.620.49--13.982.622.751.88--4.03\<.01BMI Adiposity1.140.71--1.840.601.170.71--1.920.530.240.02--2.810.251.480.92--2.390.11 Overweight1.210.89--1.650.221.190.86--1.630.303.140.71--13.990.131.371.01--1.860.05 Normal weight\-\-\-\-\-\-\-\-\-\-\-- Underweight0.740.29--1.910.530.550.20--1.530.252.880.07--114.060.571.360.05--3.480.52Barthel Index^d^0.990.98--1.010.190.990.98--1.010.301.010.96--1.070.640.990.98--1.010.27Depressive symptoms^e^1.151.08--1.22\<.011.141.07--1.22\<.011.421.01--1.990.041.141.07--1.21\<.01MMSE^f^0.600.35--1.030.06\-\-\-\-\--0.690.41--1.170.17Notes: OR Odds Ratio, Alpha was set to 0.05^a^Participants without care support^b^Participants with care support^c^use of analgesics: dichotomized^d^Barthel Index: score 0--100^e^GDS score 0--15^f^MMSE: score 0--30, cut-off ≤25 for mild cognitive impairment, \> 25 no cognitive impairment Model 1 -- Overall pain ratings {#Sec11} ------------------------------- In model 1 we tested the association of demographic and clinical characteristics on the overall sample. Male sex was statistically significantly associated with lower PRS (OR 0.61, 95% CI 0.45--0.84) while contrary associations were found for age. Individuals between 90 to 94 years of age scored significantly lower in the PRS (OR 0.65, 95% CI 0.48--0.88) than the younger age bracket. Considering the housing situation higher PRS was significantly associated with participants living at home with care support. There is a 1.6 higher possibility of experiencing pain for this group than living at home without care support (OR 1.60, 95% CI 1.01--2.53). There was also a significant association for analgesics. Participants receiving analgesics experience twice as much pain (OR 2.17, 95% CI 1.48--3.16). Furthermore higher PRS was significantly associated with depression (OR 1.15, 95% CI 1.08--1.22). No significant evidence showed for differences in education, BMI or Barthel-Index. Model 2 and 3 - MMSE status {#Sec12} --------------------------- In model two and three we divided the sample in NCI and MCI participants and found significant associations for both groups: Again male sex was significantly associated with lower pain ratings for both groups (NCI: OR 0.61, 95% CI 0.44--0.85 and MCI: OR 0.21, 95% CI 0.05--0.93). Significant associations for age appeared according to model 1 for NCI aged 90 to 94 years old. The older age group scored significantly lower in the PRS (OR 0.61, 95% CI 0.44--0.84). No association with age was found for the group the MCI-participants. Concerning the housing situation living at home with care support was significantly associated with higher ratings on the PRS for NCI (OR 1.70, 95% CI 1.04--2.78) and significantly associated with lower ratings on the PRS for MCI-participants living in a care-home (OR 0.08, 95% CI 0.01--0.48). Also for both groups higher PRS was significantly associated with depression (NCI: OR 1.14, 95% CI 1.07--1.22 and MCI: OR 1.42, 95% CI 1.01--1.99). Significant associations for analgesics were found for NCI. Those taking analgesics reported twice as much pain (OR 2.12, 95% CI 1.42--3.18). No significant figures appeared for education, BMI or Barthel-Index. Model 4 - impairment in daily activities {#Sec13} ---------------------------------------- In model 4 we analyzed the impairment in daily activities for the overall sample. Again we found a significant association for lower impairment in daily activities with male sex (OR 0.59, 95% CI 0.43--0.80), analgesics (OR 2.75, 95% CI 1.88--4.03) and depression (OR 1.14, 95% CI 1.07--1.21). The housing situation showed significant less impairment in daily activities for participants living in a care home (OR 0.51, 95% CI 0.28--0.93) and more impairment for participants living at home with care support (OR 1.72, 95% CI 1.08--2.74). For BMI stronger impairment in daily activities was significantly associated with overweight participants (OR 1.37, 95% CI 1.01--1.86). Education and Barthel-Index did not reach statistical significance. Discussion {#Sec14} ========== This was one of a few existing studies focusing on the prevalence of pain and associated factors such as age, gender, use of analgesics, cognitive state, medication and depression among the population of 85+ year olds. Age {#Sec15} --- The study demonstrated a high prevalence of pain (63%) among the age group of 85+ and strong experience impairments with everyday life due to pain (69%). Additionally, our findings suggest that older adults report less pain. These findings are supported by Zyczkowska (2007) \[[@CR25]\] who reported decreasing pain scores with growing age for both men and women. The researchers name a changing, more accepting attitude towards pain with increasing age, a "survival bias" meaning only the healthiest managed to reach very old age as possible grounds for these results. In depth research could provide more distinct answers into what leads to these changes in old age and may help overcome fears of ageing. Gender {#Sec16} ------ Regardless of the cognitive state, men seem to experience less pain and impairment in everyday life due to pain. According to these findings, female gender could increase the risk of experiencing pain. Similar finding have been reported in literature across all age groups \[[@CR6], [@CR25], [@CR26]\]. Reasons can be differences in individual pain perception, personal coping strategies or social settings \[[@CR27], [@CR28]\]. Gaining a better understanding of the different kinds of pain may also play an important role and may allow deeper insight of coping strategies and physiological factors in men and women \[[@CR29], [@CR30]\]. Housing situation {#Sec17} ----------------- Regarding the housing situation, our data show differences for the housing arrangements chosen in late life. In our sample, 47.8% of women and 34.5% of men aged 90+ years are living in care homes where activities of daily living are reduced and support through care staff is given in many areas \[[@CR1]\] which may reduce possible pain hazards. Furthermore, it can be speculated that the availability and home visits of general practitioners are at a higher frequency than in any other housing setting which could have positive effects on pain management. It may also explain why on the other hand participants living at home receiving care experience significantly more pain and more impairment in activities of daily living. Health care services providing care in the community are generally under immense time pressure and restriction of duties applied by the indication of care level or previous health care assessments e.g. supplying medication, changing bandaging, wash the person. It is also unclear whether pain assessment is part of health care services in the community by default nor if caring relatives focus on the issue. Hence the differences in pain prevalence point to a gap in pain management in
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187, 45804, 6418, 10673, 221, 34698, 22323, 13442, 18757, 6088, 38011, 31355, 5832, 13484, 6418, 187, 14274, 28915, 100, 12613, 117, 6344, 27098, 19067, 6449, 34609, 9736, 47169, 187, 45804, 6957, 209 ]	iw: חשיבה שמתאמת בין סוגי הטיפול במקום לפצל אותם. חשיבה המבוססת על האוכלוסיה ועל הקהילה, במקום על בית החולים והרופאים. וחשוב מכל, עלינו לנטוש את המודל הרפואי המסורתי ולעבור למודל שמתחשב בגורמים החברתיים שביסוד הבריאות. כיום אנו מבינים שבריאותה של אוכלוסיה נקבעת בראש ובראשונה ע"י גורמים שאינם הטיפול הרפואי, או בתי החולים ומשרדי הרופאים. למעשה, אלה קובעים רק 10% מבריאותה של הקהילה. יתר ה-90% הם גורמים התנהגותיים וחברתיים. מה כוונתי ב"גורמים חברתיים שקובעים את המצב הבריאותי"? כוונתי לגורמים כגון מצב חברתי-כלכלי, הזדמנויות השכלה, בטחון תעסוקתי ובטחון מקום העבודה, דיור, שכונות בטוחות, מעמד חברתי, ומה שבמיוחד חשוב בעיני: התחושה שיש לכם מקום בחברה, Spanish: Uno que coordine los cuidados, no uno que lo fragmente. Uno que se base en la comunidad y en la población, en vez de uno basado en el hospital y los médicos. Y, lo que es más importante, tenemos que cambiar el sistema de atención sanitaria tradicional por uno que haga frente a los factores sociales que repercuten en la salud. Y ahora entendemos que la salud de la población está determinada sobre todo por factores que son de asistencia médica, ni hospitalaria ni consultas médicas. De hecho, esto solo constituye el 10% de lo que determina la salud de una comunidad. El otro 90% depende de factores sociales y de comportamiento. Y, ¿a qué me refiero con factores sociales que repercuten en la salud? Me refiero a factores como el nivel socioeconómico, las oportunidades educativas, el puesto de trabajo y la seguridad laboral, la vivienda, los barrios seguros, el estatus social y uno que es especialmente importante para mí: sentir que tienen un lugar en la sociedad, Russian: Та, которая координирует лечение, а не разваливает его. Та, которая ориентирована на население и общество, а не на больницу и врача. И нам, самое главное, необходимо перейти с традиционной медицинской модели на модель, которая охватывает социальные факторы здоровья. Мы понимаем, что здоровье населения обусловлено преимущественно другими факторами, помимо лечебной работы, больниц и кабинетов врачей. В сущности, они составляют всего 10% того, что определяет здоровье общества. Остальные 90% — это поведенческие и социальные факторы. Что же я подразумеваю под социальными факторами здоровья? Я имею в виду такие факторы, как социально-экономический статус, возможности для получения образования, профессия и гарантия рабочего места, жильё, безопасные районы, социальный статус, и особенно важным для меня является осознание того, что ты являешься частью общества, Portuguese: Um que coordene a assistência à saúde, em vez de fragmentá-la. Um que tenha como base a população e a comunidade, em vez de hospitais e médicos. E nós, principalmente, precisamos abandonar o modelo médico tradicional por um modelo que adote as determinantes sociais de saúde. Hoje, entendemos que a saúde de uma população é predominantemente determinada por fatores alheios aos cuidados clínicos, a hospitais e a consultórios. Na verdade, eles somam apenas 10% do que determina a saúde de uma comunidade. Os outros 90% são fatores comportamentais e sociais. O que quero dizer por determinantes sociais de saúde? Quero dizer fatores como a situação socioeconômica, as oportunidades de educação, a segurança profissional e no trabalho, moradia, bairros seguros, status social e um que é especialmente importante para mim: a sensação de se ter um lugar na sociedade, Spanish: sentir que tienen un sistema de asistencia social, sentir que los valora. Y sabemos que aquellos que se sienten infravalorados sufren mala salud. Cuando estaba en acogida, vi a niños que no tenían la oportunidad de recibiruna educación y ahora sé que si no conseguían un título de secundaria, eran cinco veces más propensos a tener peor salud que yo, que tenía formación universitaria. Y vi a niños que solo habían vivido en la pobreza, y ahora sé que son ocho veces más propensos a tener mala salud que sus compañeros más afortunados. Mis experiencias me han mostrado la relación entre estos factores sociales sanitarios y el estado de salud de una comunidad y de una persona. Y estas realidades exigen que hagamos frente a los factores sociales que repercuten en la salud Y este es mi mensaje: la salud no es solo responsabilidad de los médicos. Japanese: あなたが社会的保証制度を得ていると感じていることそしてあなたが尊重されていると感じていることです私は尊重されていないと感じる人は不健康であることを知っています私が
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281, 253, 1786, 187, 7955, 2688, 15, 4325, 253, 1929, 2219, 285, 19749, 46321, 24835, 13, 309, 2797, 4209, 2739, 187, 20612, 2476, 29892, 326, 253, 40501, 22462, 369, 4518, 3636, 347, 253, 48615, 4958, 15, 187, 42, 840, 11580, 253, 10301, 13, 6730, 253, 9189, 13, 2797, 3081, 29892, 13, 285, 187, 49845, 1243, 37263 ]	you name it — to hand out souvenir token coins. Often, these tokens could be redeemed for special offers — like a free meal, free admission, or something like that. Even places like Chuck E. Cheese used to have tokens that you could use to play arcade games. Many of these old tokens are collectible and are worth $1 to $5. Rare tokens, such as those that were used during the Civil War era, are worth hundreds of dollars. Big Coins “I have a large Indian Head penny. Is it rare? What’s it worth?” I’ve gotten this specific question more than a few times over the years. I actually own one of these replica coins, and I bought it for $4 at an old-timey tourist gift shop in Florida. Large coins like this are neat-looking replicas, but that’s all they are. They’re not legal tender in any way. Most of these big coins are made from base metals and aren’t typically worth more than $3 to $5. Big coins come in many different designs. I’ve personally seen the following: Large Lincoln pennies Large Buffalo nickels Large Jefferson nickels Large Mercury dimes Large Roosevelt dimes Large Washington quarters Large Walking Liberty half dollars Large Franklin half dollars Large Kennedy half dollars Large Morgan silver dollars Large Peace silver dollars Large Eisenhower dollars While none of these big coins are rare or valuable, they make great conversation pieces and look cool on the mantle. Tiny Coins “I have a tiny Kennedy half dollar. What’s it worth?” On the opposite end of the spectrum are tiny coins that look like the real thing but are only a fraction of the size of their regular coin counterparts. In fact, they’re tiny novelty coins. Some of them were made for doll play sets. Some are play money. But those realistic-looking, mini coins that you may have are small novelty coins that are 100% true to the original coins they replicate — they’re just a fraction of the size! I bought a few of these tiny coins just for the fun of owning some. They’re worth 50 cents to $1 apiece, and while they’re not rare (and certainly aren’t legal tender), they’re still pretty awesome to hold in the hand. Two-Headed Coins (Or Coins With Two “Tails” Sides) “Why does my nickel have Jefferson on both sides? What’s this two-headed coin worth?” I always hate breaking the news to people that these coins aren’t valuable and, technically, they aren’t even legal tender. These two-headed (or double tails) coins are usually fantasy pieces that were made by hollowing out the side of one coin right up to the rim and meticulously (and snugly) fitting another coin inside the shell. Normally, two-headed coins are made for illusionists or people who want to win bar bets. Exonumia coins like this are worth anywhere from 25 cents to a few dollars as novelty coins. But they aren’t rare, and you don’t want to try spending any as real money! Coins That Are Blank On One Side However, modern minting techniques make it virtually impossible to strike a coin that looks perfect on one side and completely blank on the other. NOTE: There are some real error coins that look weak or somewhat mutilated on one side. Different types of error coins like this exist, and based on the origin of the error are worth between $5 and $100 (or more). Normally, when people ask me questions about coins that are blank on one side, the photo I end up seeing is a coin that looks normal on one side but has tiny grooves or striations on the “blank” side. That typically means somebody sanded away or sheared off the other side and later polished it to look like the coin was really struck only on one side. Blank coins are real coins that have been terribly mutilated to look like unusual one-sided coins. Often, they’re produced for illusionists or people fascinated with fantasy coins or other exonumia oddities. For the most part, these one-sided coins may be neat to look at, but have no monetary value in the general coin collector market. Colorized Coins “My American Silver Eagle is painted red, white, and blue. What’s it worth?” Colorized coins are real coins that have been altered outside of the U.S. Mint. Some private mints will colorize regular Washington quarters, American Silver Eagle coins, or other pieces and sell them as special novelty coins. While these painted coins are often beautiful works of coin art, they are not rare and aren’t valuable. In numismatic terms, colored coins are usually worth only whatever the intrinsic metal content of the coin itself is worth. Other Types Of Strange Coins I’m a roller coaster junkie, a weather enthusiast, a frequent traveler, and a numismatist. My love for coins began when I was 11 years old. I primarily collect and study U.S. coins produced during the 20th century. I’m a member of the American Numismatic Association (ANA) and the Numismatic Literary Guild (NLG). I’ve also been studying meteorology and watching weather patterns for years. I enjoy sharing little-known facts and fun stuff about coins, weather, travel, health, food, and living green… on a budget. MORE LIKE THIS ... FREE U.S. COINS NEWSLETTER VIA EMAIL Stay up to date with what's happening on The U.S. Coin Guide. From finding Rare Coins to determining Coin Values and other Fun Things To Do With Coins... you'll always be the first to see these helpful tips as soon as we publish a new article.Search Results ENGL 201. English Literature to 1800. 3 Hours. A study of works representative of the major writers and periods from the Middle Ages through the 18th century, with emphasis on critical understanding of these works and on the influences that produced them. Prerequisite: (ENGL 101 with a minimum grade of D or HUM 101 with a minimum grade of D) and ENGL 102 with a minimum grade of D.A considerable number of food poisoning incidents occur every year in every major community. Such incidents often go unrecognized; and many recognized incidents are not reported to the health authorities. But occasionally the nature of the illness is so distinctive, the latent interval sufficiently short, and the numbers of people involved and the circumstances are such that a number of victims report their illnesses to the health department. These are the visible part of the food poisoning "iceberg", and it is imperative that all such reports be carefully received and recorded on a standard Food Poisoning Report form, by the epidemiologist, a designated public health nurse or sanitarian. Each report should then be promptly examined by the community epidemiologist, and whenever the nature and circumstances of the reported illness warrants it, an appropriate investigation must be quickly performed, initially by telephone. Often an investigation is triggered by a cluster of two or more reports closely associated in nature, time, and place. Herewith a number of food poisoning investigation reports from my files, which may be useful for neophyte epidemiologists when confronted with similar incidents: Occasionally we received bogus reports of food-borne illness; some from obvious cranks, or persons seeking to develop a basis for suing a restaurant or manufacturer; which wasted the time of one or more of us. And not infrequently, someone would bring a can or bottle with dubious contents and demand that we analyze the contents "for any poisonous substance". To do such an open-ended examination for every conceivable poison that might be in a specimen would require exorbitant expenditure of laboratory and manpower resources. But if we summarily refused to examine any such specimen, the offended party might soon complain about our disinterest to political officials, with repercussions. Hence, we ordinarily accepted such specimens, to be held in a refrigerator or freezer pending submission of one or more stool specimens, By requiring submission of a designated number of stool specimens before undertaking any extensive laboratory examination requested, we fended off many cranks few of whom are willing to go to the trouble of submitting multiple stool specimens. During my seven years with the Seattle-King County Health Department, I investigated many food poisoning outbreaks, some of which were quite memorable; and for some of which I have found reports. One such I remember, but for which I do not yet find a report, was from "The Maison Blanche" restaurant (no longer operative). It came to my notice because a number of prominent business persons who ate lunch there became sufficiently ill with high fever and diarrheal illness that they were hospitalized, and Salmonella Typhimurium isolated from their feces. These cases were reported to the health department. From the known cases and luncheon companions, I obtained sufficient food consumption histories that the crab salad was clearly identified as the offending vehicle. I then visited the restaurant, examined the facilities, obtained additional histories, and obtained rectal
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776, 3114, 13, 627, 403, 247, 2257, 273, 952, 751, 479, 835, 2622, 6498, 3038, 816, 1053, 457, 85, 789, 1425, 187, 187, 1989, 5909, 253, 11008, 3548, 457, 85, 253, 990, 14, 455, 273, 521, 5827, 15, 401, 483, 91, 310, 2819 ]	ila of the Road Runner and Coyote because the cliffs surrounding the cala are a deep orange similar to the cartoon! Cala Xarraca, Cala Tarida, Cala Xuclar and all the little rock pools around Figueretes and are some of the favourites. We hear Ibiza has several markets held weekly on the island. Any favourites? There are so many markets; I wish I had made it to more! There is a massive 'Hippy Market' in Punta Arabi, which is definitely worth a visit. You could spend the whole day there, as it's so big. They have live music and children's workshops so it's a great day out for the family. Friends of ours married on Formentera recently and had such a relaxing trip with their entire tribe. Do you guys go there? Formentera is paradise! We have only been once but we would love to go back and spend more time there. Fomentera is only a half-hour ferry ride from Ibiza so definitely a must-do while you are there, even if only for a day! We also love Mallorca, which is the larger island north of Ibiza. Weather-wise, when is the best time of year to visit Ibiza? We have always been in the summer so we can escape the Australian 'winter' but I would love to go in their winter. The locals say it has such a cool vibe and is so different to the tourist-packed summer. I really noticed this year how busy Ibiza was getting each day we were there so if you do go in summer, just be prepared for crowds. August is the busiest so I really enjoy June and September there as it's still warm but not crazy busy. Where do you usually stay and can you recommend any family-friendly areas? We have always stayed in the south-west of the island around Playa d'en Bossa, Figueretes and Talamanca. We prefer this area as it's close to the Old Town of Eivissa and not as touristy as it is around San Antonio on the other side of the island. Playa d'en Bossa is a main party area so can get a little crazy at night but I always felt fine having Lila there during the day and early evening. There are certainly more chilled parts of the island if you would prefer to be away from the action. I'd recommend hiring a car, as it’s the best way to see the island. Nothing is too far, and we would jump in the car and just go exploring. Everywhere is well signposted so we never used a GPS, which I loved as it reminded me of the old days. Anything else you wish to share about your travels that likeminded families may love to read? My biggest tip for travelling to Spain with children is to go with the flow! It's such a different lifestyle to ours in Australia and if you get caught up with staying in what may be a typical home routine, you might miss out on some of the fun! Lila is a night owl anyway but in Spain, she would go to bed late and sleep in late and we found that fit in better with Ibiza life. The sun doesn't set until 9.30ish in summer so the evenings are lovely to enjoy at the beach or outdoors. We enjoyed so many sunsets together which was really special. Also encourage your children to try the local foods and learn the language. It's amazing how adventurous they can be and what knowledge they take in.NEW DELHI -- India and France have joined hands to spearhead a global "solar revolution" with an aim to generate one terawatt of energy by 2030, an ambitious goal that requires $1 trillion in funds. "There are financial and regulation hurdles and capacity hurdles," said visiting French President Emmanuel Macron at the founding conference of the International Solar Alliance here on Sunday. He added the private and public sectors and society needed to come together to overcome these challenges. Indian Prime Minister Narendra Modi is the chief architect of the ISA that he launched with then French President Francois Hollande in Paris in November 2015 during a convention on climate change. The alliance involves 121 prospective member-countries that fall between the Tropics of Cancer and Capricorn, and are exposed to the "maximum solar intensity of over 300 days a year," acording to a bureaucrat at the Indian external affairs ministry. The ISA aims to facilitate the large-scale deployment of solar energy in those countries, that are home to 73% of the world's population -- by aggregating the demand for funding, technology and innovation. Indian Prime Minister Narendra Modi and French President Emmanuel Macron with other participants at the first conference of the International Solar Alliance in New Delhi on March 11. (Photo courtesy of Press Information Bureau of India) So far, 62 countries have signed the ISA framework agreement, out of which 32 have already ratified it. Australia, Bangladesh, Cuba, France, Ghana, India, Papua New Guinea, Sudan, Sri Lanka, Togo, the United Arab Emirates and Venezuela are among those that have ratified the agreement. These nations, Macron said, have 138 gigawatt of solar power potential over the next five years. "Depending on the countries, 20-50% of population does not have access to electricity," he said, pointing to the pent-up demand. During the summit, New Delhi also announced 27 solar projects under the Indian government's credit lines in 15 countries, including Bangladesh, Chad, Congo, Ghana, Mali, Rwanda and Sri Lanka. The estimated cost of these projects is $1.4 billion. Separately, Macron and Modi on Monday inaugurated a 100-megawatt solar power plant built by French firm ENGIE in northern Uttar Pradesh state's Mirzapur area, a key step in meeting the target of 100 gigawatt of electricity in India from solar energy by 2022. Macron applauded India's efforts in expanding renewable energy capacity within two years, from 39GW to 63GW, with solar energy growing up by 140%. "You [India] attracted investment, you supported them, you are training your own people. This is what the alliance of 121 countries in Africa, Asia, Latin America and Oceania shall be doing," Macron said Sunday. France, Macron said, has already met its 2015 pledge of providing 300 million euros ($369 million) to ISA member countries, and the French development agency will allocate an additional 700 million euros to its solar energy commitments by 2022. Referring to "solar mamas," a group of African women trained as solar engineers under an Indian government program, Macron said these women "didn't wait and didn't stop because some countries decided to just leave the floor and leave the Paris agreement." They kept on moving "because they decided it's good for them, their children and grandchildren. They decided to act and keep acting," he said. Macron's comment was an oblique reference to U.S. President Donald Trump's decision to withdraw from the Paris climate agreement reached in 2015 with an aim to curb global carbon emissions and slow rising temperatures. For his part, Modi pointed out that India has started the world's largest renewable energy expansion program. "We will generate 175GW of electricity from renewables by 2022, of which 100GW of power will be from solar energy." For the ISA, he presented an action plan that includes affordable solar technology for all, low-risk finance and an increased ratio of solar power in the energy mix. "We have to ensure that a better and affordable solar technology is easily accessible to everyone," he said. "We will have to provide concessional and low-risk financing for solar projects, and develop regulatory aspects and standards to [find solutions]," he said, adding consultancy support would be required for "bankable solar projects" in developing countries. Macron's 4-day India visit concludes on Monday.New Gym in Avon Opens for Business The new Raise the Bar fitness center and gym is officially open in Avon. Photo by Joy Crist The new Raise the Bar fitness center and gym in Avon is open for business, although an official grand opening as well as 24/7 hours of operation is on the horizon, per owner Seth Foutz. Foutz, a 20+ year chef and island resident, was one of the local members affected by the closure of the Spa Koru gym at the end of 2018, but after a little mentoring from Spa Koru owner Joe Thompson, he quickly set a plan in motion to open a new gym less than a half mile away from the former one. Raise the Bar is located at the Kinnakeet Corner complex at the edge of Avon Village, and the 2,700 square foot space features high-impact floors, new walls, and a variety of equipment throughout the spacious interior. Currently, the gym is open from 8 a.m. until 8 p.m., but Foutz will soon be installing a 24-hour keyless access system that will allow members to work out on their own schedule. “Working in the restaurant industry, I never went to gym in the summer because the hours [of operation] didn’t work with my schedule,” said Foutz in an earlier interview. “And in our community, there are a lot of people like me where normal operating hours just don’t work.” But opening the doors isn’t the end-all of his plans. Foutz is looking
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Here you will see all the deals you have purchased. If you purchased a voucher from us, it will show up there as "2712 Designs". Click on the blue button "View Voucher", which will give you a download of your voucher code and instructions on how to redeem under "How to Use." Your Groupon voucher will begin with "G" and end with either "REC" , "SQ", "EMB" or "HND" depending on the item that you purchased. Not sure where you should be? Check the end of your voucher code: If your voucher code ends in REC, your voucher is valid on a rectangle stamp design which can be found here: Rectangle Stamps If your voucher code ends in SQ, your voucher is valid on a square stamp stamp design which can be found here: Square Stamps If your voucher code ends in EMB, your voucher is valid on a desk embosser stamp design which can be found here: Desk Embossers If your voucher code ends in HND, your voucher is valid on a hand embosser stamp design which can be found here: Hand Embossers Still having difficulty? 1. Make sure to click on the product link provided with your voucher to ensure you are taken to the correct product page associated with your voucher code (also see above). 2. Be sure that you copy and paste your voucher code from the purchaser and paste it into the coupon box in the checkout page. Voucher codes must be exact, missing or having just one character off will cause your voucher to be rejected. 3. Check that your voucher has not expired. Expired vouchers can be used as store credit for the paid value. Please contact for assistance if your voucher has expired. How do I redeem my voucher?Choose the stamp design that you would like under Shop > Self-Inking Stamps or Self-Inking Square Stampsand click "Order." Fill in personalization lines. Double check all spelling & punctuation and then click "Add to Cart." Repeat process if you would like to order additional stamps or click on the cart icon on the top right corner to continue to checkout. Type or paste in voucher code in the white box and then click "Apply Coupon." Once voucher code had been deducted, click on "Proceed to Checkout." Enter your billing, shipping address and payment information to complete your order. My Voucher code is not working? Please note that all of our voucher codes end with the following letters: REC - Codes ending in this will only work with rectangle stamps found here SQ - Codes ending in this will only work with square stamps found here Will I get a digital proof of my stamp? No, unfortunately a digital proof is not included in this deal. When will my stamp ship? After you have placed your order and redeemed your voucher through the 2712 Designs website, your stamp order will ship within 10-14 business days. When your order has shipped an email confirmation including tracking number will be sent to the email used to place your order through 2712 Designs. You can track your order here ---> Track My OrderI purchased more than one voucher, but it's only letting me enter one voucher? If you've purchased more than one voucher, you will need to make a separate order for each voucher code. I placed my stamp order, but would like to make a change? Once your order has been submitted we may be able to make a change as long as it has not been made. Please email us and we can assist you with this. Locating your voucher code: After you place your order with LivingSocial, they provide you with a voucher code, which you then take to our website to redeem for a stamp. Your Living Social voucher will begin with "S" and end with either "REC" , "SQ" or "EMB" depending on the item that you purchased. To view your voucher code: Sign into your LivingSocial account, click on your username at the top right hand corner, and then the drop down option "My Vouchers." Here you will see all the deals you have purchased. If you purchased a voucher from us, it will show up there as "2712 Designs". Your LivingSocial voucher will begin with "S" and end with either "REC" , "SQ", "EMB" or "HND" depending on the item that you purchased. Not sure where you should be? Check the end of your voucher code: If your voucher code ends in REC, your voucher is valid on a rectangle stamp design which can be found here: Rectangle Stamps If your voucher code ends in SQ, your voucher is valid on a square stamp stamp design which can be found here: Square Stamps If your voucher code ends in EMB, your voucher is valid on a desk embosser stamp design which can be found here: Desk Embossers If your voucher code ends in HND, your voucher is valid on a hand embosser stamp design which can be found here: Hand Embossers Still having difficulty? 1. Make sure to click on the product link provided with your voucher to ensure you are taken to the correct product page associated with your voucher code (also see above). 2. Be sure that you copy and paste your voucher code from the purchaser and paste it into the coupon box in the checkout page. Voucher codes must be exact, missing or having just one character off will cause your voucher to be rejected. 3. Check that your voucher has not expired. Expired vouchers can be used as store credit for the paid value. Please contact for assistance if your voucher has expired. Expired vouchers can be used as store credit for the paid value. Please click help on the right of the page. Please provide us with the following information: 1. Your voucher code 2. The email address you would like the store credit to be sent to Shipping fees vary by product. You can always see how much the shipping fees will be by adding what you want to the cart. Then click on the shipping calculator and the shipping fees will appear. We test all stamps functionality and quality before they are shipped, so I've included some helpful tips to ensure the best stamped image. First, I suggest removing and re-inserting your design plate as, although rare, it may have shifted while in transit. Please view the link included with a quick video on how to properly remove and insert your design plate. https://www.2712designs.com/how-to/ Here are our recommendations to get the best impression: 1. Use your stamp on a clean, dry, flat, hard surface such as a desk or non textured table. If you seem to be having difficulties with certain areas of your stamp, try stamping on a slightly cushioned surface such as an even stack of paper or a mouse pad. 2. Be sure that the item you are stamping is separate from the stack. Stamp on one layer at a time. 3. When using our stamps on enveloped, stamp before stuffing. When stamping on the flap, fold out and stamp on single surface. 4. Stamp in a clean, straight motion with even pressure. Keep the stamp body steady and do not rock as this may result in an uneven impression and unwanted ink marks. 6. While we do not recommend stamping on textured surfaces, it can be done but will most likely result in an uneven impression. 7. Our stamps are not suitable for use on glossy surfaces as the ink is water based and will not dry entirely. A speciality ink set can be purchased for glossy surfaced materials. Current processing is 10-14 business days. Rush Processing is available for an additional $30.00. Rush Processing gets your item made and shipped in 1 business day and includes USPS Priority Mail shipping (approx. 3-5 business day delivery time after shipment). If you would like this option, please select RUSH at checkout.Pharmacotherapy for hypertension in the elderly. Elevated blood pressure (known as hypertension) increases with age, and most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than diastolic hypertension, and occurs more commonly in older people. It is important to know the benefits and harms of antihypertensive treatment of hypertension in this age group. To quantify antihypertensive drug effect on overall mortality, cardiovascular mortality and morbidity and withdrawal due to adverse effects in people 60 years and older with mild to moderate systolic or diastolic hypertension. Updated search of electronic database of EMBASE, CENTRAL, MEDLINE until Dec 2008; previous search of two Japanese databases (1973-1995) and WHO-ISH Collaboration register (August 1997); references from reviews, trials and previously published meta-analyses; and experts. Randomized controlled trials of at least one year duration in hypertensive elders (at least 60 years old) comparing antihypertensive drug therapy with placebo or no treatment and providing morbidity and mortality data. Outcomes assessed were total mortality (including cardiovascular, coronary heart disease and cerebrovascular mortality); total cardiovascular morbidity and mortality (representing combined coronary heart disease and cerebrovascular morbidity and mortality); and withdrawal due to adverse events. Fifteen trials (24,055 subjects >/= 60
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STREAMS were a competing API design on System V Revision 3. With the BSD Sockets API came the select() syscall. But why was it necessary? I always thought that the "proper" Unix way to write network servers in was to create one worker process for each connection. In case of TCP/IP servers, this meant the accept-and-fork model: sd = bind (); while ( 1 ) { cd = accept ( sd ); if ( fork () == 0 ) { close ( sd ); // Worker code goes here. Do the work for `cd` socket. exit ( 0 ); } // Get back to `accept` loop. Don't leak the `cd`. close ( cd ); } While this model may be sufficient for writing basic network services 3, it's not enough for non-trivial programs. Terminal multiplexing Around 1983, Rob Pike was developing Blit, a fancy graphical terminal for Research Unix 8th Edition. Best to see it in action: Here's the Blit research paper for the curious. Blit clearly did terminal multiplexing. It allowed users to interact with multiple virtual consoles over a single physical serial link. I asked Mr. Pike about the history of select : Accept-and-fork, as you call it, makes it impossible for multiple clients to share state on the server. It's not just about networking either; one influence was the work with the Blit. While running two synchronous processes to power cu was sufficient, it wasn't enough to power Blit. Blit did require some kind of socket multiplexing facility to work smoothly. I would speculate that there was an theoretical alternative. One might try to extend the cu model and hack together a file descriptor multiplexer by spawning multiple processes blocking on I/O and having them synchronized on some kind of IPC. Unfortunately no decent IPC mechanisms existed for BSD. System V IPC was released in January 1983, but nothing comparable was implemented on BSD. I went through the 4.2BSD man pages and couldn't find any kind of real IPC4. With lack of any serious IPC mechanisms, it seems likely that Blit simply needed select to be able to do the console multiplexing. Back to sockets I contacted Kirk McKusick about the history of select . He replied: Select was introduced to allow applications to multiplex their I/O. Consider a simple application like a remote login. It has descriptors for reading from and writing to the terminal and a descriptor for the (bidirectional) socket. It needs to read from the terminal keyboard and write those characters to the socket. It also needs to read from the socket and write to the terminal. Reading from a descriptor that has nothing queued causes the application to block until data arrives. The application does not know whether to read from the terminal or the socket and if it guesses wrong will incorrectly block. So select was added to let it find out which descriptor had data ready to read. If neither, select blocks until data arrives on one descriptor and then awakens telling which descriptor has data to read. [...] Non-blocking was added at the same time as select. But using non-blocking when reading descriptors does not work well. Do you go into an infinite loop trying to read each of your input descriptors? If not, do you pause after each pass and if so for how long to remain responsive to input? Select is just far more efficient. Select also lets you create a single inetd daemon rather than having to have a separate daemon for every service. Here we are. Mr. McKusick confirms that non-blocking I/O simply didn't exist before select . Furthermore, he cites the cu terminal use case - it would be hard to write a telnet client without I/O multiplexing. Finally, he mentions inetd , which although introduced later in 4.3BSD, would have been impossible without select . Recap Having to run two processes to get cu working was a hack. With lack of any serious IPC it was impossible to emulate socket multiplexing in Blit without select . Furthermore select was needed to implement inetd . On architecture level select is needed to implement stateful servers which allow some state sharing between client connections. Here's another snippet from the "UNIX Time-Sharing System: A Retrospective" page 1966: [In UNIX] input and output ordinarily appear to be synchronous; programs wait until their I/O is completed. [...] There remain special applications in which one desires to initiate I/O on several streams and delay until the operation is complete on only one of them. When the number of streams is small, it is possible to simulate this usage with several processes. However, the writers of a UNIX ncp ("network control program") interface to the Arpanet feel that genuinely asynchronous I/O would improve their implementation significantly. Early Unix systems were pretty basic and select was simply not needed. It's not that blocking I/O model in C was deemed the best programming paradigm for everyone. This model made sense because all you could do were simple operations on files. This all was changed with the advent of network. Network application required things like inetd , stateful servers and terminal emulators like telnet . These things would be hard to implement had the OS not allowed socket multiplexing. Conclusion In this discussion I was afraid to phrase the core question. Were Unix processes intended to be CSP-style processes? Are file descriptors a CSP-derived "channels"? Is select equivalent to ALT statement? I think: no. Even if there are design similarities, they are accidental. The file-descriptor abstractions were developed well before the original CSP paper. It seems that an operating socket API's evolved totally disconnected from the userspace CSP-alike programming paradigms. It's a pity though. It would be interesting to see an operating system coherent with the programming paradigms of the user land programs. Let me leave you with a couple of vaguely related links: Ever wondered why select uses a bit mask to pass file descriptor list to kernel? Because 4.2BSD allowed only 20 file descriptors per program. uses a bit mask to pass file descriptor list to kernel? Because 4.2BSD allowed only 20 file descriptors per program. History of Actors programming model Channel I/O STREAMS and Solaris Guide and "A Stream Input-Output System" by Ritchie. mpx and mpxio or mpxcall - an early IPC / file desciptor multiplexing API. I think these were introduced in 1979 Version 7 Unix: "Multiplexed files: A feature that did not survive long was a second way (besides pipes) to do inter-process communication: multiplexed files. A process could create a special type of file with the mpx system call; other processes could then open this file to get a "channel", denoted by a file descriptor, which could be used to communicate with the process that created the multiplexed file. Mpx files were considered experimental, not enabled in the default kernel, and disappeared from later versions, which offered sockets (BSD) or CB UNIX's IPC facilities (System V) instead (although mpx files were still present in 4.1BSD)." Update: Mr. Pike clarified a bit of early history: Greg Chessons mpx was in v7 unix by the late 1970s, well before 1983 and BSD. Sockets were just one attempt in a crowded environment. The predecessor to the Blit used Greg's mpx. I think the very earliest Blit stuff did too, but by the time the movie was made v8 had happened and Dennis Ritchie gave me streams and select (but no sockets!). Select and sockets were roughly the same time but not necessarily two parts of one thing. The last statement is telling. select came at the same time as sockets, but it wasn't implemented purely for networking. It seems that all of multiplexing, sockets and IPC came at about the same time, without a coherent grand design. A number of people helped with this article: Rob Pike, Kirk McKusick, Ólafur Guðmundsson, Martin J. Levy, David Wragg and Tony Garnock-Jones. Thanks! Update: In a twitter exchange Clifford Heath noted that there was nonblocking I/O on TTY devices before 1983. There was nonblocking I/O before 1983. The University of Melbourne CS dept paused in 1980/1 to play Hack, and I used it for Pacman. I wonder how it worked. What ioctl's did it use and what were the semantics. Perhaps read() was nonblocking? Upate: Paul Ruizendaal followed up this blog post with some more investigation into early history. His findings are documented in The History of Unix mailing list: Continue reading about Select() being fundamentally broken →[2019/03/28] "Pretty Guardian Sailor Moon" The Super Liveを彩る楽曲たちの配信が決定しました！明日3月29日(金)より、iTunesとApple Musicの2サイトで、1曲ごとにダウンロード購入が可能となります。 ※全楽曲Instrumentalでの配信となります。さらに、ア
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83, 768, 18, 16, 21, 724, 1569, 2553, 4038, 6222, 13, 342, 495, 37, 2716, 14, 14611, 9941, 7224, 83, 1126, 1109, 44218, 11971, 380, 3302, 1979, 273, 253, 653, 248, 2631, 4447, 275, 247, 13649, 24362, 390, 7592, 17620, 310, 873, 407, 247, 5019, 273, 2341, 14144, 285, 2432 ]	the SMBH mass to grow at a rate given by ${\epsilon_{\rm heat}}c^2 {\dot M}_{\rm BH} = L_{\rm cool}$. We adopt values ${f_{\rm Edd}}= 0.01$ and ${\epsilon_{\rm heat}}=0.02$ for these parameters, based on @Fanidakis15. The results in this paper are not very sensitive to these values. (@Bower08 considered an alternative AGN feedback scheme in [<span style="font-variant:small-caps;">galform</span>]{}, in which energy input from AGN is able to expel most of the hot gas halo, rather than just balance radiative cooling. However, in this paper we retain the simpler @Bower06 AGN feedback scheme, in line with other [<span style="font-variant:small-caps;">galform</span>]{}papers.) Dynamical processes {#ssec:dynamics} ------------------- Galaxies evolve according to a variety of dynamical processes, as we now describe. ### Galaxy mergers We classify galaxies into [central]{} galaxies, which sit at the centres of their DM halos and can grow by accreting gas which cools in that halo, and [satellite]{} galaxies which orbit within the DM halo, and are assumed not to accrete any gas from the hot gas halo. When DM halos merge, we assume that the central galaxy in the most massive progenitor halo becomes the new central galaxy, while all other galaxies are left as satellites in the new halo. Satellite galaxies merge with the central galaxy in their host DM halo on a timescale set by [dynamical friction]{}. In @Cole00, we used a dynamical friction timescale which was calculated analytically from the Chandraskhar dynamical friction formula, but did not include the effects on the dynamical friction rate of tidal stripping of the DM subhalo hosting the satellite galaxy. In the new model, we replace this with a modified expression obtained by fitting to the results of cosmological N-body/hydrodynamical simulations of galaxy formation [@Jiang08; @Jiang10], which automatically incorporates the effects of this tidal stripping: $$\begin{aligned} \lefteqn{\tau_{\rm merge} = } \nonumber \\ & & \frac{f(\epsilon)}{2 C} \frac{M_{\rm pri}}{M_{\rm sat}} \, \frac{1}{\ln\left( 1 + M_{\rm pri}/M_{\rm sat} \right)} \, \left( \frac{{r_{\rm circ}}}{{r_{\rm vir}}} \right)^{1/2} \, \tau_{\rm dyn,halo} . \label{eq:taumerge}\end{aligned}$$ This gives the time for a satellite to merge with the central galaxy from when it falls in through the virial radius of the main halo, in terms of the masses $M_{\rm sat}$ of the satellite system (galaxy plus DM halo) and $M_{\rm pri}$ (galaxies plus DM halo) of the primary at infall, and [circularity]{} $\epsilon$ of the satellite orbit (at infall), defined as the ratio of the orbital angular momentum to that of a circular orbit of the same energy in the same potential, and ${r_{\rm circ}}$, the radius of this equivalent circular orbit. The constant $C=0.43$, while $f(\epsilon) = 0.90 \epsilon^{0.47} + 0.60$ is the fit found by @Jiang08. In applying this formula, we draw a random value of $\epsilon$ for each satellite from the probability distribution of orbital parameters of infalling satellite halos measured by @Benson05 from cosmological N-body simulations. The merger time is calculated when the satellite first falls into the main halo. If the satellite has not merged with the central galaxy by the time of the next halo mass doubling event, then the merger time is recalculated for the new halo, drawing a new value of $\epsilon$ from the distribution. [ (Note that, since we calculate the galaxy merger timescale analytically, rather than using the orbit of the satellite galaxy subhalo measured from the N-body simulation used in constructing the halo merger trees, our galaxy merger timescales are not affected by galaxies becoming “orphaned”, i.e. losing their subhalos due to effects of limited numerical resolution.)]{} The result of a galaxy merger depends on the ratio of baryonic mass (including both stars and cold gas) of the satellite, $M_{\rm b,sat}$, to that of the central galaxy, $M_{\rm b,cen}$. We define two different thresholds, ${f_{\rm burst}}\leq {f_{\rm ellip}}\leq 1$. (a) Mergers with $M_{\rm b,sat}/M_{\rm b,cen} > {f_{\rm ellip}}$ are classed as [major]{}. We assume that any stellar disks are destroyed and transformed into a stellar spheroid, while all of the cold gas collapses into the newly formed spheroid. Other mergers are classed as [minor]{}. In minor mergers, stars from the satellite are added to the spheroid of the central galaxy, but the cold gas is added to the disk of the central galaxy, without changing the specific angular momentum of the latter. (b) Mergers with $M_{\rm b,sat}/M_{\rm b,cen} > {f_{\rm burst}}$ (which includes all major mergers) trigger starbursts, in which all of the cold gas from the merging galaxies is transferred to the spheroid and then consumed by star formation or ejected by the resulting SN feedback. Numerical simulations of galaxy mergers imply ${f_{\rm ellip}}\sim 0.3$ and ${f_{\rm burst}}\sim 0.1$ [e.g. @Mihos94; @Barnes98; @Hopkins09]. We treat ${f_{\rm ellip}}$ and ${f_{\rm burst}}$ as adjustable parameters, but only in small ranges around these values. ### Disk instabilities Galaxies can also undergo morphological transformations and trigger starbursts due to disk instabilities. Galaxy disks which are dominated by rotational motions are unstable to bar formation when they are sufficently self-gravitating. Based on the work of @Efstathiou82, we assume that disks are dynamically unstable to bar formation if $${F_{\rm disk}}\equiv \frac{{V_{\rm c}}({r_{\rm disk}})}{\left( 1.68 \, G{M_{\rm disk}}/{r_{\rm disk}}\right)^{1/2}} <{F_{\rm stab}}, \label{eq:disk_stability}$$ where ${M_{\rm disk}}$ is the total disk mass (stars plus gas), ${r_{\rm disk}}$ is the disk half-mass radius, and the factor $1.68$ relates this to the disk exponential scalelength.[^9] The quantity ${F_{\rm disk}}$ measures the contribution of disk self-gravity to its circular velocity, with larger values corresponding to less self-gravity and so greater disk stability.[^10] @Efstathiou82 found a stability threshold ${F_{\rm stab}}\approx 1.1$ for a family of exponential stellar disk models, while @Christodoulou95 found ${F_{\rm stab}}\approx 0.9$ for a family of gaseous disks. We treat ${F_{\rm stab}}$ as an adjustable parameter in the range $0.9 {\lesssim}{F_{\rm stab}}{\lesssim}1.1$, with larger values resulting in more disks becoming unstable. Note that a completely self-gravitating stellar disk would have ${F_{\rm disk}}=0.61$. If the disk satisfies the instability condition ${F_{\rm disk}}<{F_{\rm stab}}$ at any timestep, then we assume that the disk forms a bar, [ which then thickens due to vertical buckling instabilities and evolves into a spheroid [@Combes90; @Debattista06]. We assume that this newly formed spheroid incorporates all of the stellar mass of the pre-existing disk and of any pre-existing spheroid. We also assume that bar formation triggers a starburst that consumes any cold gas present.]{} While in reality the timescale for growth of the bar and its evolution into a bulge is likely to be at least several disk dynamical times, in the model we approximate this whole process as happening instantaneously, as soon as the disk instability condition is met. Galaxy sizes {#ssec:sizes} ------------ Our model for galaxy sizes is identical to that in @Cole00. Galaxies consist of a disk and a spheroid embedded in a DM halo. These three components interact with each other gravitationally. (a) We assume that the disk has an exponential surface density profile, with a half-mass radius ${r_{\rm disk}}$ that is set by angular momentum conservation and by centrifugal equilibrium in the combined gravitational potential of disk, bulge and halo. When the disk accretes gas by cooling from the halo, it is assumed to gain angular momentum equal to that which this gas had in the halo before it cooled. When the disk loses gas through SN feedback, this is assumed to leave the specific angular momentum of the disk unchanged. Apart from this, the disk angular momentum remains constant, but the disk radius adiabatically adjusts in response to changes in the gravitational potential. (b) We assume that the spheroid is spherical and has an $r^{1/4}$ law surface density profile, with 3D half-mass radius ${r_{\rm bulge}}$. The initial size of the spheroid formed in a galaxy merger or disk instability is set by a combination of energy conservation and vir
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313, 70, 15, 72, 904, 444, 6189, 19, 481, 4683, 2282, 13, 253, 575, 4537, 476, 5206, 841, 2634, 301, 65, 84, 15744, 13, 533, 1563, 841, 13991, 476, 1361, 342, 6927, 7103 ]	exp}$ by forcing a biomass dependent flux through a suited maintenance reaction, e.g., hydrolysis of ATP into ADP and phosphate. Note that the flux we need to force through maintenance strongly depends on how detailed the model is and how much lumping of reactions has been done. We therefore cannot provide an order of magnitude approximation for how much flux should be forced. Modelers should however be aware that the need for a large ATP maintenance forced flux to match experimental growth rates is an indication of model errors or poor model quality. Using a maintenance reaction makes sense also from a biological perspective, since one can usually not claim that the constructed resource allocation model covers all energy expending processes in an actual cell, so such an ATP maintenance reaction serves the purpose of modeling this remaining energy expenditure. 8. The SBML Representation of a Resource Allocation Model {#sec8-metabolites-07-00047} ========================================================= For metabolic network models used together with constraint-based modeling, it is standard to define them in the systems biology markup language (SBML), an XML-based way of representing models (<http://sbml.org/Main_Page>). However, there is so far no specific way of representing resource allocation models, which come with several extra ingredients in addition to the metabolic network part. Therefore, in this section we propose a way of making use of the existing SBML capabilities for representing resource allocation models \[[@B13-metabolites-07-00047]\]. We illustrate this proposal using a toy resource allocation model listed in [Table 3](#metabolites-07-00047-t003){ref-type="table"} for which we attach the SBML representation in the Supplement. 8.1. Compartments {#sec8dot1-metabolites-07-00047} ----------------- We keep any compartments present from the original reconstruction of the metabolic network. If possible, we place species objects for the additional gene products in the compartments in which the corresponding enzymes are acting. This means, e.g., that enzymes are located where the reactions they catalyze are happening. Species without any real physical location in the model, e.g., lumped species, can be placed arbitrarily in any compartment. Note that the compartments are not used in the formulation of the deFBA problem, besides the identification of external species. 8.2. Species {#sec8dot2-metabolites-07-00047} ------------ As postulated by the SBML standard, each `species` object must contain the attributes: `id``compartment``constant (true or false)``boundaryCondition (true or false)``hasOnlySubstanceUnits (true or false)``initialAmount` All species in the model also contain a `ram:species` annotation. We distinguish between limiting extracellular metabolites, for which the amount changes by cellular uptake (as N${}_{1}$ and N${}_{2}$ in the toy model), nonlimiting extracellular metabolites, where the amount is assumed to be unchanged by cellular uptake (as O${}_{2}$ in the toy model), intracellular metabolites (N, AA, ATP), storage (Stor), and biomass components (ETrans1, ETrans2, EMetab1, EMetab2, EStor, S, R). As per SBML specifications, a `boundaryCondition` value of `true` means a differential equation derived from the reaction definitions should not be generated for the species. Thus, in RAM, the nonlimiting extracellular species should have `boundaryCondition` = "`true`" as the amount of species at the systems boundary cannot be changed by the reactions, while all other species should have `boundaryCondition` = "`false`". The mandatory attribute `constant` is used in RAM, as per SBML definition, to specify whether a species amount is assumed to be changing or not in a deFBA simulation. With the deFBA approach this can only be `constant` = "`true`" for nonlimiting boundary species. Still, these species should only have `constant` = "`false`" if they are changed by extracellular processes such as oxygen through gas exchange. All other species will always have `constant` = "`false`". In order to generate the mathematical model for the deFBA problem in terms of molar amounts, each external, storage, and biomass species element must be assigned an initial value, either by setting the `initialAmount` attribute and `hasOnlySubstanceUnits` = "`true`", or by setting the `initialConcentration` attribute, `hasOnlySubstanceUnits` = "`false`", and specifying the `size` attribute of the respective compartment. Other mathematical models may require less information, for example for RBA it would be sufficient to specify the amounts or concentrations of the external species. We show in [Table 4](#metabolites-07-00047-t004){ref-type="table"} examples on how to set the mandatory species fields for each metabolite type. In addition to the required SBML fields listed above, each species must have a RAM annotation `ram:speciesType` specifying its type. We distinguish between the species types "`extracellular`", which can be either limiting or nonlimiting extracellular species"`metabolite`", which are species that obey the quasi-steady-state approximation Constraint ([5](#FD5-metabolites-07-00047){ref-type="disp-formula"})"`storage`", which represent the storage species $\mathcal{C}$"`enzyme`", which represent species $\mathcal{P}$ with catalytic role involved in Constraint ([7](#FD7-metabolites-07-00047){ref-type="disp-formula"})"`quota`", which represent quota species $\mathcal{P}$ that are enforced using Constraint ([9](#FD9-metabolites-07-00047){ref-type="disp-formula"}) The biomass species have additionally an annotation field `ram:molecularWeight` for storing their molecular weight $w_{i}$, an annotation field `ram:objectiveWeight` for their objective weight $b_{i}$, and an annotation field `ram:biomassPercentage` for their the biomass percentage $\phi_{i}$. The `ram:biomassPercentage` attribute contains the fractions of the quota components ([8](#FD8-metabolites-07-00047){ref-type="disp-formula"}) that need to be enforced at each time point. Below we show the annotation fields for the ribosome and the structural component as examples. Ribosome R: <species id="R" name="Ribosome" compartment="cytosol" initialAmount="0.03364" constant="false" boundaryCondition="false" hasOnlySubstanceUnits="true"> <annotation> <ram:RAM xmlns:ram="https://www.fairdomhub.org/sops/304"> <ram:species ram:molecularWeight="weight_R" ram:objectiveWeight="weight_R" ram:biomassPercentage="zero" ram:speciesType="enzyme"/> </ram:RAM> </annotation> </species> Structural component S: <species id="S" name="Structural biomass component" compartment="cytosol" initialAmount="0.7499" constant="false" boundaryCondition="false" hasOnlySubstanceUnits="true"> <annotation> <ram:RAM xmlns:ram="https://www.fairdomhub.org/sops/304"> <ram:species ram:molecularWeight="weight_S" ram:objectiveWeight="weight_S" ram:biomassPercentage="bp_S" ram:speciesType="quota"/> </ram:RAM> </annotation> </species> Note that "`weight_R`", "`weight_S`", "`zero`", "`bp_S`" are `id`s of parameters defined in the list of parameters of the SBML model. ### 8.2.1. Guideline to Ensure Uniqueness of Macromolecule IDs {#sec8dot2dot1-metabolites-07-00047} There are some enzymes that can act in different compartments of the cell, cf. [Section 4.5](#sec4dot5-metabolites-07-00047){ref-type="sec"}. An example is fumarase, which catalyzes reactions both in the cytosol and in the mitochondrion in yeast. While we include the respective compartments for the species in their description, a potential error is to give both enzymes the same `id`, either in their `species` or their `fbc:geneAssociation` representation. Hence, we suggest to name enzymes in a specific pattern combining, e.g., their name and their respective location. If the enzyme is acting in only one compartment we choose its `id` in the format "Main_id\_\[acting-compartment\]". If the enzyme is a transporter between two compartments we choose "Main_id\_\[compartment1\]\_\[compartment2\]". If the enzyme is translated from only one gene (e.g., ETrans1), this represents the main `id`. For enzyme complexes made of multiple gene products we suggest simply using "E\[id(s) of catalyzed reactions\]" as main `id` (e.g., ETrans2). Of course, the user can choose these `id`s freely, but following these suggestions can help with easier evaluation
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556, 721, 1797, 2786, 695, 11411, 15, 329, 495, 14, 6967, 3540, 313, 783, 1072, 3540, 327, 512, 22916, 10, 310, 1925, 247, 16657, 15, 5815, 3540, 310, 4272, 715, 9654, 19465, 15, 5815, 8776, 4428, 23414, 11061, 273, 941, 15, 3813, 253, 2972, 1979, 275, 253, 10883, 2829, 310, 6705, 9851, 475, 9654, 19465, 475, 23414 ]	will have suffered the most, given their infrastructures would be too weak to withstand the power of a category 5 cyclone," said Suva resident Alice Clements, a spokeswoman for UNICEF in the Pacific. "Families may have lost their homes and crops, therefore leaving them without shelter, food and a livelihood." Although not hit directly, the capital, Suva, endured damaging gale-force winds, heavy rain and power outages. Clements, who was in Suva when the storm struck, said the city experienced "destructive, howling winds, and the sound of rivets lifting from roofs a constant throughout the night." More than 1,200 people were in evacuation centers around the country, the disaster management ministry said. The Colonial War Memorial Hospital in Suva suffered extensive water damage, and the roof of a local hospital was blown off in the northwestern town of Ba, said Sune Gudnitz, head of the U.N. Office for the Coordination of Humanitarian Affairs regional office for the Pacific. Widespread flash flooding and coastal inundation -- flooding in normally dry land -- "is likely as storm surges may push the sea inland several hundred meters," the Red Cross said. The western city of Nadi, on Fiji's main island, suffered minor wind damage but experienced extensive flooding, CNN affiliate TVNZ reported Fiji, an archipelago collectively about the size of New Jersey, lies in the South Pacific Ocean some 1,800 miles from Australia's east coast. (By comparison, Hawaii is about 2,500 miles from Los Angeles.) Most of the nation's 900,000 residents live on one of two main islands: Viti Levu or Vanua Levu.Breuil-le-Vert Breuil-le-Vert is a commune in the Oise department in northern France Population See also Communes of the Oise department References INSEE Category:Communes of OiseNotícias em Português 24 members - Público - Observador - Diário Económico - RTP Notícias - Agência Lusa Admin: Notícias de Publicações Portuguesas:- Público- Observador- Diário Económico- RTP Notícias- Agência LusaAdmin: @tiaaaagoo If you have Telegram, you can view and join Notícias em Português right away.Please log in Register now for free First Name * Last Name * Email * A valid e-mail address. All e-mails from the system will be sent to this address. The e-mail address is not made public and will only be used if you wish to receive a new password or wish to receive certain news or notifications by e-mail. Rereading the Fossil Record: The Growth of Paleobiology as an Evolutionary Discipline Most palaeontologists now take it for granted that our subject has significant things to say about the nature of evolutionary change; uniquely, we have the time dimension. Yet the fossil record is undeniably incomplete, and until quite recently, a prevailing view - among population geneticists, for example - was that palaeontologists had little to offer. As the evolutionary biologist John Maynard Smith put it, they should "go away and find another fossil, and not bother the grown-ups". Not so many biologists hold such views now. There is a good reason for it, almost entirely due to the labours of a small but exceptionally vigorous group of US palaeontologists for some 15 years during the 1970s and 1980s. The whole concept of palaeontology changed dramatically, and a separate discipline, palaeobiology, was born, with its own journal: Paleobiology. Palaeontology may, or may not, have a seat at the "high table" of evolutionary biology (if there is such a thing). But this group did an extraordinary job of trying to get there. This splendid book tells a fascinating tale; here we find the gentlemanly Norman Newell, the young tigers Niles Eldredge and Stephen Jay Gould, the brilliant, prickly Tom Schopf, the innovative David Raup, the late Jack Sepkoski (father of the author), Steven Stanley, James Valentine and many other extraordinary personalities. We read of their insights, interactions, disagreements, quarrels, personal lives and contributions. Sadly, not a few died before their time. The critical figure among them was the late Gould, but they all needed each other, despite quarrelling. So what were the basic concepts of palaeobiology? Effectively, it made palaeontology less descriptive and more theoretical, invoked computer modelling and quantitative analysis of the fossil record, brought in biological evolutionary concepts and emphasised the evolutionary implications of the fossil record. None of this would have been possible without new technology; namely, modern high-speed computers. A critical question was whether the patterns of change seen in the fossil record are real. Eldredge and Gould proposed "punctuated equilibria" in 1972 - in other words, rather than even and slow transformation of populations, there was rapid origin of new types, in small populations, followed by longer periods of stasis. On the other hand, Schopf was convinced that most evolutionary change was stochastic - largely random, uninfluenced by external causes. His computer-generated "spindle" models closely matched patterns seen in nature, and he never abandoned this idea. Gould, meanwhile, believed (rightly in my view) in determinism by natural selection. Raup generated computer models of coiled mollusc shells, of which only a fraction of possible forms are used in nature. Extinctions came to be seen as highly important drivers of evolution, resetting the scenario each time. By the 1980s, five major mass extinctions had been recognised, with causes identified. Jack Sepkoski's ideas of three successive "evolutionary faunas", originating, evolving and becoming extinct together, gained wide acceptance. So did Stanley's concept that evolution above the species level was decoupled from species selection. Other ideas, such as a 26-million-year periodicity in extinctions, flourished briefly before dying. Our perspective on the fossil record and its value for evolution changed immensely as a result of this work. Palaeontology is now much more biological, although still firmly rooted in the fossil record. We recognise that evolution is hierarchical, with genes, organisms, populations, species and genera representing different levels, and these are (or may be) operating independently. The new synthesis is not anti-Darwinian, as has been claimed. Rather, to quote David Sepkoski: "Modern evolution theory is remarkable for the continuing validity of Darwin's original insights, and also for its adaptability." That is the take-home message, and it is absolutely true. Rereading the Fossil Record: The Growth of Paleobiology as an Evolutionary Discipline5. Partitioning with fdisk This section shows you how to actually partition your hard drive with the fdisk utility. Linux allows only 4 primary partitions. You can have a much larger number of logical partitions by sub-dividing one of the primary partitions. Only one of the primary partitions can be sub-divided. Examples: Four primary partitions (see Section 5.2) Mixed primary and logical partitions (see Section 5.3) 5.1. fdisk usage fdisk is started by typing (as root) fdisk device at the command prompt. device might be something like /dev/hda or /dev/sda (see Section 2.1.1). The basic fdisk commands you need are: p print the partition table n create a new partition d delete a partition q quit without saving changes w write the new partition table and exit Changes you make to the partition table do not take effect until you issue the write (w) command. Here is a sample partition table: Disk /dev/hdb: 64 heads, 63 sectors, 621 cylinders Units = cylinders of 4032 * 512 bytes Device Boot Start End Blocks Id System /dev/hdb1 * 1 184 370912+ 83 Linux /dev/hdb2 185 368 370944 83 Linux /dev/hdb3 369 552 370944 83 Linux /dev/hdb4 553 621 139104 82 Linux swap The first line shows the geometry of your hard drive. It may not be physically accurate, but you can accept it as though it were. The hard drive in this example is made of 32 double-sided platters with one head on each side (probably not true). Each platter has 621 concentric tracks. A 3-dimensional track (the same track on all disks) is called a cylinder. Each track is divided into 63 sectors. Each sector contains 512 bytes of data. Therefore the block size in the partition table is 64 heads * 63 sectors * 512 bytes er...divided by 1024. (See The first line shows the geometry of your hard drive. It may not be physically accurate, but you can accept it as though it were. The hard drive in this example is made of 32 double-sided platters with one head on each side (probably not true). Each platter has 621 concentric tracks. A 3-dimensional track (the same track on all disks) is called a cylinder. Each track is divided into 63 sectors. Each sector contains 512 bytes of data. Therefore the block size in the partition table is 64 heads * 63 sectors * 512
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The Polonization of Vilnius proceeded through the influx of Polish elements and assimilation of non-Polish burghers. It started in the late 14th century with the arrival of Polish clergy, followed by artisans and merchants; they migrated in larger numbers after the Polish court of Sigismund August moved to the city. Polish-Lithuanian Commonwealth After the Union of Lublin (1569) that created the Polish–Lithuanian Commonwealth, the city flourished further in part due to the establishment of Vilnius University by Stephen Báthory, King of Poland and Grand Duke of Lithuania in 1579. The university soon developed into one of the most important scientific and cultural centers of the region and the most notable scientific center of the Grand Duchy of Lithuania. Political, economic and social life was in full swing there. This is among all proven by the Lithuanian Statutes issued in the 16th century, the last of which was still in force until the 19th century. In 1610 the city was racked by a large fire. In 1769 the Rasos Cemetery was founded; today it is one of the oldest surviving cemeteries in the city. Rapidly developing, the city was open to migrants from both East and West. In addition to old citizens, larger Jewish, Orthodox and German communities established themselves in the city. Each group made its contribution to the life of the city, and crafts, trade and science prospered. In the 17th century, Polish and polonized elements achieved a cultural and likely numerical preponderance. In 1655 during the Russo-Polish War in 1654–1667 Vilnius was captured by the forces of Tsardom of Russia and was pillaged, burned and the population was massacred. The death toll of around 20,000 included a large proportion of Vilnius Jews. The city's growth lost its momentum for many years, yet the number of inhabitants recovered. During the decline of the Commonwealth, Vilnius became known as "Jerusalem of the North" - a major religio-cultural center of Eastern European Jewry. Russian Empire After the Third Partition of Polish-Lithuanian Commonwealth in 1795, Vilnius was annexed by the Russian Empire and became the capital of Vilna Governorate, a part of the Northwestern Krai. In order to allow the city to expand, between 1799–1805 period, the city walls were pulled down, only the Dawn Gate (also known as Aušros vartai, Medininkų vartai or Ostra Brama, Вострая Брама) remained. In 1803 Alexander I re-established the Polish-language University. In 1812 the city was seized by Napoleon on his push towards Moscow. After the failure of the campaign, the Grande Armée retreated to the area where 80,000 of French soldiers died and were buried in the trenches they had built months earlier. After the November Uprising the Vilnius University was closed and repressions halted the further development of the city. Civil unrest in 1861 was suppressed by the Imperial Russian Army. During the January Uprising in 1863 heavy city fights occurred, but were brutally pacified by Mikhail Muravyov, nicknamed The Hanger by the population because of the number of executions he organized. After the uprising, Polish language was banned from public use. The Latin alphabet was prohibited in 1859 (Belarusian language) and in 1865 (Lithuanian language) - the ban was lifted in 1904. During the second half of 19th and the beginning of 20th century Vilnius also became one of the centers of Jewish, Polish, Lithuanian and Belarusian national rebirths. According to the 1897 Russian census, by mother tongue, 40% of the population was Jewish, 31% Polish, 20% Russian, 4.2% Belarusian and 2.1% Lithuanian. Jewish culture and population was so dominant that some Jewish national revival leaders argued for a new Jewish state to be founded in a Vilnius region, with a city as its capital. These national revivals happened in Vilnius because it was one of the most tolerant, progressive and liberal places in a region, legacy of the tolerance deriving from the years of the Grand Duchy of Lithuania. One of the most important Polish, Belarusian poets and writers published their works in Vilnius at that time. It was the place where the first short-lived Belarusian weekly Naša Niva was founded. Vilnius became an important place of act of the Lithuanian national revival on 4–5 December 1905, when the Great Seimas of Vilnius was held in the Palace of the present-day National Philharmonics, with over 2000 delegates from all regions of Lithuania as well as emigrees. It was decided to make a demand to establish an autonomous ethnic Lithuanian state within the Russian Empire with its parliament (Seimas) in Vilnius. Cultural life was revived after the 1905 Russian Revolution. Society of Friends of Science in Wilno was created in 1906 in order to practice science and literature in Polish language. The Emilia and Eustachy Wróblewski Library, the center of Polish culture, was established in 1912, around that time also Polish theater was revived. Polish cultural life was still repressed despite its revival. In 1907 bishop Eduard von der Ropp was expelled from Vilnius to Vitebsk. Interwar period Polish-Lithuanian conflict During World War I, Vilnius was occupied by Germany from 1915 until 1918. Still under German occupation, Council of Lithuania proclaimed the Act of Independence of Lithuania in Vilnius on 16 February 1918. Act proclaimed restoration of the independent state of Lithuania with Vilnius as its capital. The German civilian administration of the Ober-Ost declined to pass full authority to Lithuania, which was not controlled by the Germans any more. Instead, the Germans tried to control the area by means of promoting conflicts between local nationalities as it became clear that the German plan for creation of Mitteleuropa, a net of satellite buffer states, failed. Finally, on 1 January 1919, the German garrison withdrew and passed the authority over the city to a local Polish committee, against the pleas of the Lithuanian administration. A Polish administration started to be formed. Former members of the local Polish Self-Defence formations, now formally enlisted into the Polish Army, took over the posts while the Lithuanians withdrew along with the Germans. On 5 January 1919 the city was taken by Bolshevik forces advancing from the east. Vilnius was proclaimed the capital of the Lithuanian–Byelorussian Soviet Socialist Republic. For the next 4 months the city became a communist experiment in governance. During the course of that conflict, on 19 April 1919 the city was again seized by Poland (Vilna offensive), this time by forces of the regular Polish Army. A year later, on 14 July 1920, it was lost to Soviet forces again (this time, the Soviets were aided by Lithuanians, who were promised Vilnius). Shortly after the defeat in the Battle of Warsaw in 1920, the withdrawing Red Army handed the city over to Lithuania, in accordance with the Soviet–Lithuanian Peace Treaty of 12 July 1920. The treaty allowed for the transfer to Lithuanian authority of some part of the areas of the former Grand Duchy of Lithuania. Although the city itself, as well as its surroundings were actually transferred, the fast pace of the Polish offensive prevented additional territories to be handed over by the Red Army and the disputed area was split into Lithuanian and Polish-controlled parts. Many historians argue that the main reason behind the Soviet agreement with Lithuania was to weaken Poland and hand the disputed territories to a weaker state, which Lithuania was at the time, in order to reconquer the area more easily after the retreat of the Red Army had halted. Also, the independence of the Baltic States was seen by Lenin as temporary. However, after the Battle of the Niemen River the Red Army was again defeated and Bolshevik Russia was forced to abandon her plans for reincorporation of all the lands lost by the Russian Empire in the Treaty of Brest-Litovsk. As Russia ceased to be a major player in the area, Polish-Lithuanian relations worsened. In demographic terms Vilnius was one of the most Polonized and Russified of Lithuanian cities during 1795-1914 Russian rule, with Lithuanians constituting a mere fraction of the total population: 2% - 2,6% according to Russian (1897), German (1916) and Polish (1919) censuses. The latter two indicated that 50,1% or 56,2% of the inhabitants were Poles, while the Jewish share in the population amounted to 43,5% or 36,1% (they were conducted after large part of the inhabitants of Vilnius were evacuated to Russia, mostly Voronezh because of war in 1915). The Lithuanians nonetheless have strong historical claim to the city (former capital of the Grand Duchy of Lithuania, the very center of the formation of medieval Lithuanian state) and refused to recognize any Polish claims to the city and the surrounding area. Lithuanian national activists, for example: Mykolas Biržiška and Petras Klimas, supposed Poles and Belarusians in the Vilnius province to be "Slavicized Lithuanians" who, regardless of their individual preferences,
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спецпідрозділів (так званих "маски-шоу") на обшуках; слідчий матиме право це робити лише у випадках загрози для життя чи здоров’я учасників слідчих дій і тільки на підставі ухвали слідчого судді. Нарешті, парламент поклав край ходінню співробітників різних правоохоронних органів по черзі на одне і те ж саме підприємство за одним і тим самим фактом "можливого порушення" законодавства. Йдеться про ситуації, коли спочатку приходить запит від СБУ чи поліції, а через кілька місяців за цим самим фактом в двері стукає прокуратура з ухвалою слідчого судді, бо інформація передається "між своїми" по колу. Тепер закон не дозволяє правоохоронним органам проводити розслідування і навіть зобов’язує закрити кримінальне провадження, якщо є не скасована постанова слідчого про закриття кримінального провадження щодо того ж діяння, яке вже розслідувалось з дотриманням вимог по підслідності. Законопроект №7275 є беззаперечним першим кроком вперед на шляху захисту підприємств та їх службових осіб від свавілля з боку правоохоронців, але дотримання його положень буде значною мірою залежати від того, хто та як його виконуватиме. Поки наші правоохоронні органи залишаються фактично не реформованими, я маю певний скепсис, що ухвалений закон запрацює на корить бізнесу. Тому, уряду варто бути послідовним та зробити другий, більш важливий крок: створити фінансову поліцію та ліквідувати економічні підрозділи прокуратури, нацполіції та податкову міліцію, а також оперативні "економічні" підрозділи СБУ. Якщо ми боремося за підприємця та інвестиційний клімат, то повинні нарешті створити один дієвий орган, який буде розслідувати злочини проти публічних фінансів держави. Третій рік фінансова поліція, на заміну податкової міліції та іншим "економічним" підрозділам, лише обговорюється. Депутатський законопроект майже два роки не ставили на голосування і не розглядали в Раді. Мінфін його переробив на догоду силовикам в бік погіршення, однак, навіть у такому, спотвореному, вигляді, так і не спромігся зареєструвати в Раді. В грудні цього року відбудеться Національна рада реформ з цього питання та анонсоване внесення президентом нового законопроекту — про Бюро фінансової безпеки. Для мене не принципово, як називатиметься новий орган. Натомість, важливо, щоб новий орган з самого початку його створення не був політично залежним і не став кишеньковим "військом" для когось з можновладців для зведення рахунків з політичними опонентами, конкурентами тощо. Це має бути новий центральний орган виконавчої влади, окремий від ДФС, від МВС, від будь-яких інших органів: - сформований на конкурсній основі, за аналогією з НАБУ, який не втручається в роботу бізнесу до встановлення факту злочину; - з посиленою аналітичною, а не силовою функцією; - з обмеженням для колишніх силовиків на роботу в ньому; - орган, який буде розслідувати всі злочини проти публічних фінансів держави, органів місцевого самоврядування, зловживань із міжнародною допомогою та кредитами. Але найголовніше — це те, щоб нова фінансова поліція була незалежною від політичних впливів, в тому числі і від президента, уряду, окремих політиків і виконувала просту функцію: карати тих, хто ухиляється від сплати податків, а не тих, хто наповнює бюджет. Тільки політична незалежність нового органу та чесний конкурсний добір керівництва, детективів, аналітиків забезпечать належний результат: чесний бізнес зможе спокійно займатися своєю господарською діяльністю, а не відбиватись чи відкупатись від
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PSA testing without clinical indication for prostate cancer in relation to socio-demographic and clinical characteristics in the Danish Diet, Cancer and Health Study. Social differences in prostate cancer (PC) incidence and mortality might be related to testing for prostate-specific antigen (PSA). Although routine PSA screening is not recommended in Denmark, testing without clinical indication increased during the past decade. We evaluated associations between socio-demographic or clinical characteristics and PSA testing without clinical indication. In the Danish Diet, Cancer and Health Cohort, we identified 1051 men with PC diagnosed in 1993-2008. Diagnostic and clinical characteristics were obtained from medical records, and socio-demographic information was retrieved from administrative registers. We used general logistic regression analysis to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between socio-demographic or clinical characteristics and PSA testing without clinical indication. Cox regression analysis was used to examine associations with mortality. PSA testing without clinical indication was less likely among patients > 67 years (OR 0.7; 0.5-1.0). Men who were, PSA tested without clinical indication, were more likely to have vocational training (OR 1.8; 1.1-2.9) or higher education (OR 1.5; 0.9-2.5) and less likely to have advanced disease (OR 0.6; 0.4-0.9). PSA testing without clinical indication more often preceded therapy with curative intent (OR 1.8; 1.1-2.9) and less often palliative treatment (OR 0.6; 0.3-1.0). Men who were PSA tested without clinical indication had non-significantly lower overall and PC-specific mortality [hazard ratios 0.8 (0.5-1.2) and 0.6 (0.3-1.1), respectively]. PSA testing without clinical indication was associated with higher educational level. PC detected by PSA testing with no clinical indication was more often localized and treated with curative intent. From Lithuania, with Love (2018) - diodorus https://roadsandkingdoms.com/2018/from-lithuania-with-love/ ====== tasdomas What an interesting glimpse at a period that lives on the edge of my consciousness. I was 3 at that time, but I remember going to rallies with my parents a few years later. I also remember tanks and APCs parked all over Vilnius after the events of January 13th, 1991. The amount of respect, gratitude and admiration I feel for the people who drove the independence movement forward is difficult to describe. And then, every once in a while I meet somebody from Russia or some other post-soviet state and hear them longing for those "long gone days" or ask me "is it really that much better for you now?". It is. Much better. Sure, we have problems. Social and economical ones. But at least they are our problems. And we have the freedom to solve them on our own. ~~~ Fins It is certainly much better. And much nicer to visit than back then. ------ dTal I'm surprised at the lack of mention of the human chain, which is the most famous act of protest on the 23 August: "Approximately two million people joined their hands to form a human chain spanning 675.5 kilometres (419.7 mi) across the three Baltic states – Estonia, Latvia, and Lithuania, which were considered at the time to be constituent republics of the Soviet Union." A stark contrast with the article, which says "Only a few hundred people showed up". [https://en.wikipedia.org/wiki/Baltic_Way](https://en.wikipedia.org/wiki/Baltic_Way) ~~~ tasdomas The Baltic way was in 1989, two years after the first demonstration - maybe that's why the article did not mention it. Regardless, that too was a spectacular thing to do. ~~~ dTal Ah, my mistake. Still, a surprising omission, as the seminal anti-Soviet protest in Lithuania, and within the author's memory. module Vale.Stdcalls.X64.AesHash open FStar.HyperStack.ST module B = LowStar.Buffer module HS = FStar.HyperStack open FStar.Mul module DV = LowStar.BufferView.Down module UV = LowStar.BufferView.Up open Vale.Def.Types_s open Vale.Interop.Base module IX64 = Vale.Interop.X64 module VSig = Vale.AsLowStar.ValeSig module LSig = Vale.AsLowStar.LowStarSig module ME = Vale.X64.Memory module V = Vale.X64.Decls module IA = Vale.Interop.Assumptions module W = Vale.AsLowStar.Wrapper open Vale.X64.MemoryAdapters module VS = Vale.X64.State module MS = Vale.X64.Machine_s open Vale.AES.AES_s module GF = Vale.AES.X64.GF128_Init let uint64 = UInt64.t (* A little utility to trigger normalization in types ) noextract let as_t (#a:Type) (x:normal a) : a = x noextract let as_normal_t (#a:Type) (x:a) : normal a = x [@__reduce__] noextract let b128 = buf_t TUInt8 TUInt128 [@__reduce__] noextract let t128_mod = TD_Buffer TUInt8 TUInt128 default_bq [@__reduce__] noextract let t128_no_mod = TD_Buffer TUInt8 TUInt128 ({modified=false; strict_disjointness=false; taint=MS.Secret}) [@__reduce__] noextract let dom: IX64.arity_ok_stdcall td = let y = [t128_no_mod; t128_mod] in assert_norm (List.length y = 2); y ( Need to rearrange the order of arguments *) [@__reduce__] noextract let key128_pre : (Ghost.erased (Seq.seq nat32)) -> VSig.vale_pre dom = fun (s:Ghost.erased (Seq.seq nat32)) (c:V.va_code) (input_b:b128) (output_b:b128) (va_s0:V.va_state) -> GF.va_req_Keyhash_init c va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as_vale_buffer output_b) [@__reduce__] noextract let key128_post : (Ghost.erased (Seq.seq nat32)) -> VSig.vale_post dom = fun (s:Ghost.erased (Seq.seq nat32)) (c:V.va_code) (input_b:b128) (output_b:b128) (va_s0:V.va_state) (va_s1:V.va_state) (f:V.va_fuel) -> GF.va_ens_Keyhash_init c va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as_vale_buffer output_b) va_s1 f #set-options "--z3rlimit 20" [@__reduce__] noextract let key128_lemma' (s:Ghost.erased (Seq.seq nat32)) (code:V.va_code) (_win:bool) (input_b:b128) (output_b:b128) (va_s0:V.va_state) : Ghost (V.va_state & V.va_fuel) (requires key128_pre s code input_b output_b va_s0) (ensures (fun (va_s1, f) -> V.eval_code code va_s0 f va_s1 /\ VSig.vale_calling_conventions_stdcall va_s0 va_s1 /\ key128_post s code input_b output_b va_s0 va_s1 f /\ ME.buffer_writeable (as_vale_buffer input_b) /\ ME.buffer_writeable (as_vale_buffer output_b) )) = let va_s1, f = GF.va_lemma_Keyhash_init code va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as
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285, 1463, 281, 253, 7441, 449, 187, 11336, 273, 253 ]	The specific challenge is to balance... the state's interest in protecting the granddaughter's constitutional rights under the First Amendment of the United States Constitution to visit her grandparents ... and ... the parents' constitutional rights under the Fourteenth Amendment of the United States Constitution to control [the granddaughter's] life." Continuing, the grandparents assert that Code §§ 20-124.2 and 16.1-241 require that a court balance the interests of the state and the interests of the parents; that the circuit court has appropriately balanced the rights of all parties and found by clear and convincing evidence that their granddaughter's best interests would be served by requiring her to have limited visitation with her grandparents; and that the challenged statute is constitutional. Responding, the parents contend that Code § 20-124.2(B), as applied to them, is unconstitutional because the statute infringes upon their Fourteenth Amendment rights to conduct their family affairs free from governmental intrusion. B. The Fourteenth Amendment of the United States Constitution provides in relevant part that "[n]o state shall ... deprive any person of life, liberty, or property, without due process of law...." U.S. Const. amend. XIV, § 1. The United States Supreme Court, explaining the protections accorded by the Fourteenth Amendment, has stated: "While this Court has not attempted to define with exactness the liberty thus guaranteed, the term has received much consideration and some of the included things have been definitely stated. Without doubt, it denotes not merely freedom from bodily restraint but also the right of the individual to contract, to engage in any of the common occupations of life, to acquire useful knowledge, to marry, establish a home and bring up children, to worship God according to the dictates of his own conscience, and generally to enjoy those privileges long recognized at common law as essential to the orderly pursuit of happiness by free men." Meyer v. Nebraska, 422 262 U.S. 390, 399 [43 S.Ct. 625, 67 L.Ed. 1042] (1923). The Supreme Court observed in Moore v. East Cleveland, 431 U.S. 494, 499, 97 S.Ct. 1932, 52 L.Ed.2d 531 (1977), that it "has long recognized that freedom of personal choice in matters of marriage and family life is one of the liberties protected by the Due Process Clause of the Fourteenth Amendment" (quoting Cleveland Bd. of Educ. v. LaFleur, 414 U.S. 632, 639-40, 94 S.Ct. 791, 39 L.Ed.2d 52 (1974)). Additionally, the United States Supreme Court has stated its "historical recognition that freedom of personal choice in matters of family life is a fundamental liberty interest protected by the Fourteenth Amendment," Santosky v. Kramer, 455 U.S. 745, 753, 102 S.Ct. 1388, 71 L.Ed.2d 599 (1982), and that there is "a `private realm of family life which the state cannot enter.'" Moore, 431 U.S. at 499, 97 S.Ct. 1932 (quoting Prince v. Massachusetts, 321 U.S. 158, 166, 64 S.Ct. 438, 88 L.Ed. 645 (1944)). Accord Lassiter v. Department of Soc. Servs., 452 U.S. 18, 27, 101 S.Ct. 2153, 68 L.Ed.2d 640 (1981). The Supreme Court of the United States has made clear that a state may interfere with a parent's right to raise children only when the state acts in its police power to protect the health or safety of the child. See Wisconsin v. Yoder, 406 U.S. 205, 230, 92 S.Ct. 1526, 32 L.Ed.2d 15 (1972) (Amish children would not be harmed by receiving an Amish education instead of attending public high school); Prince, 321 U.S. at 170, 64 S.Ct. 438 (Supreme Court approved conviction of a guardian who allowed a child to sell religious magazines, finding a legitimate state interest in preventing psychological or physical injury to the child); Pierce v. Society of Sisters, 268 U.S. 510, 534, 45 S.Ct. 571, 69 L.Ed. 1070 (1925) (parents' decisions to send their children to private schools was not inherently harmful to children). Here, I am concerned with the parents' fundamental rights to raise their child as they deem appropriate. Therefore, any statute which seeks to limit those rights can only be justified by a compelling state interest, and such statute must be narrowly drawn to express only the legitimate state interest at stake. Washington v. Glucksberg, ___ U.S. ___, ___, 117 S.Ct. 2258, 2268, 138 L.Ed.2d 772 (1997); Reno v. Flores, 507 U.S. 292, 301-02, 113 S.Ct. 1439, 123 L.Ed.2d 1 (1993). Thus, this Court must consider whether Code § 20-124.2(B), as applied in this case, requires a finding of a compelling state interest before a court can interfere with the parents' fundamental rights to raise their child by awarding visitation to the grandparents over the parents' objections. VI. A. The language contained in Code § 20-124.2(B) is clear and unambiguous and, therefore, I would look no further than the plain meaning of the language contained in the statute to ascertain its meaning. Supinger v. Stakes, 255 Va. ___, 205-206, 495 S.E.2d 813, 817; City of Winchester v. American Woodmark Corp., 250 Va. 451, 457, 464 S.E.2d 148, 152 (1995). This Court has stated: "`While in the construction of statutes the constant endeavor of the courts is to ascertain and give effect to the intention of the legislature, that intention must be gathered from the words used, unless a literal construction would involve a manifest absurdity. Where the legislature has used words of a plain and definite import the courts cannot put upon them a construction which amounts to holding the legislature did not mean what it has actually expressed.'" Barr v. Town & Country Properties, Inc., 240 Va. 292, 295, 396 S.E.2d 672, 674 (1990) (quoting Watkins v. Hall, 161 Va. 924, 930, 172 S.E. 445, 447 (1934)); accord Supinger, 255 Va. at 206-07, 495 S.E.2d at 817-18; Haislip v. Southern Heritage Ins. Co., 254 Va. 265, 268-69, 492 S.E.2d 135, 137 (1997); Abbott v. Willey, 253 Va. 88, 91, 479 S.E.2d 528, 530 (1997); Weinberg v. Given, 252 Va. 221, 225-26, 476 S.E.2d 502, 504 (1996). B. In making visitation determinations, a juvenile and domestic relations district court must comply with the statutes contained in 423 Title 20, Chapter 6.1 of the Code, which is entitled, "Custody and Visitation Arrangements for Minor Children."[2] This chapter contains numerous statutes which relate to custody and visitation. Code § 20-124.1, which is contained in Chapter 6.1, makes clear that grandparents and certain other non-parents, are deemed to have a statutory interest in child visitation.[3] Code § 20-124.2 is entitled "Court-Ordered Custody and Visitation Arrangements." Code § 20-124.2(B) authorizes a court to award visitation to a non-parent with a legitimate interest. Code § 20-124.2(B) also establishes the standard that a court must apply when making a visitation determination. The court's determination must be based upon a showing by clear and convincing evidence that the best interests of the child would be served by an award of visitation. Code § 20-124.3, which establishes the factors that the court shall consider when applying the best interests of the child standard, states in part: "§ 20-124.3. Best interests of the child.In determining best interests of a child for purposes of determining ... visitation arrangements ... the court shall consider the following: "1. The age and physical and mental condition of the child, giving due consideration to the child's changing developmental needs; "2. The age and physical and mental condition of each parent; "3. The relationship existing between each parent and each child, giving due consideration to the positive involvement with the child's life, the ability to accurately assess and meet the emotional, intellectual and physical needs of the child; "4. The needs of the child, giving due consideration to other important relationships of the child, including but not limited to siblings, peers and extended family members; "5. The role which each parent has played and will play in the future, in the upbringing and care of the child; "6. The propensity of each parent to actively support the child's contact and relationship with the other parent, the relative willingness and demonstrated ability of each parent to maintain a close and continuing relationship with the child, and the ability of each parent to cooperate in matters affecting the child; "7. The reasonable preference of the child, if the court deems the child to be of reasonable intelligence, understanding, age and experience to express such a preference; "8. Any history of family abuse as that term is defined in § 16.1-228; and "9. Such other factors as the court deems necessary and proper to the determination." None of the
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9, 1826, 26688, 9, 412, 15, 788, 29008, 29681, 35632, 26688, 15, 15522, 64, 29681, 558, 535, 50274, 32315, 9, 412, 15, 788, 29981, 15738, 2548, 5715, 187, 50261, 29008, 6825, 26692, 12535, 15, 1311, 1703, 64, 10560, 64, 32847, 20982, 558, 535, 50274, 32315, 9, 412, 15, 788, 21595, 22147, 5023, 2703, 3902, 5715, 346, 3287, 535, 50274, 8271, 13141, 9 ]	Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. / / * Copyright (C) 2009-2020 Ping Identity Corporation * * This program is free software; you can redistribute it and/or modify * it under the terms of the GNU General Public License (GPLv2 only) * or the terms of the GNU Lesser General Public License (LGPLv2.1 only) * as published by the Free Software Foundation. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program; if not, see <http://www.gnu.org/licenses>. / package com.unboundid.ldap.protocol; import java.io.ByteArrayInputStream; import org.testng.annotations.Test; import com.unboundid.asn1.ASN1Buffer; import com.unboundid.asn1.ASN1BufferSequence; import com.unboundid.asn1.ASN1Element; import com.unboundid.asn1.ASN1Integer; import com.unboundid.asn1.ASN1OctetString; import com.unboundid.asn1.ASN1Sequence; import com.unboundid.asn1.ASN1StreamReader; import com.unboundid.ldap.sdk.DN; import com.unboundid.ldap.sdk.GenericSASLBindRequest; import com.unboundid.ldap.sdk.LDAPException; import com.unboundid.ldap.sdk.LDAPSDKTestCase; import com.unboundid.ldap.sdk.ReadFromFilePasswordProvider; import com.unboundid.ldap.sdk.SimpleBindRequest; import com.unboundid.util.LDAPSDKUsageException; /* * This class provides a set of test cases for the {@code BindRequestProtocolOp} * class. / public class BindRequestProtocolOpTestCase extends LDAPSDKTestCase { /* * Provides test coverage for the constructor which takes a string DN and a * string password. * * @throws Exception If an unexpected problem occurs. / @Test() public void testBindRequestProtocolOpSimpleStringPassword() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp( "uid=test.user,ou=People,dc=example,dc=com", "password"); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), new DN("uid=test.user,ou=People,dc=example,dc=com")); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), "password"); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /* * Provides test coverage for the constructor which takes a string DN and a * binary password. * * @throws Exception If an unexpected problem occurs. / @Test() public void testBindRequestProtocolOpSimpleBinaryPassword() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp( "uid=test.user,ou=People,dc=example,dc=com", "password".getBytes()); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op= BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), new DN("uid=test.user,ou=People,dc=example,dc=com")); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), "password"); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /* * Provides test coverage for the constructor which takes a string DN and a * string password with an anonymous bind. * * @throws Exception If an unexpected problem occurs. / @Test() public void testBindRequestProtocolOpSimpleStringPasswordAnonymous() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp(null, (String) null); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), DN.NULL_DN); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), ""); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /* * Provides test coverage for the constructor which takes a string DN and a * binary password. * * @throws Exception If an unexpected problem occurs. */ @Test() public void testBindRequestProtocolOpSimpleBinaryPasswordAnonymous() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp(null, (byte[]) null); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), DN.NULL_DN); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), ""); assertNull(
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These tract homes would displace a smaller original settlement built into the dunes called Carville, which was so named for squatters that lived in abandoned horsecars (horse-drawn trolleys) and cable cars that were dumped in the sand dunes. Development increased by the 1930s, as the Sunset was built and developed into a streetcar suburb. The post–World War II baby boom in the 1950s saw the last of the sand dunes leveled down and replaced with more single- and multifamily homes. In these developments, built mostly by Henry Doelger, entire blocks consist mainly of houses of the same general character, differentiated by variations in their stucco facades and mirrored floorplans, with most built upon lots with no free space between houses. Later, Oliver Rousseau built more individualistic homes in the district. Historically, the Sunset's demographics were consisted mostly of European Americans, specifically Irish and Italian. Beginning in the late 1960s the neighborhood saw a steady influx of Asian (mostly Chinese) immigrants following the Immigration and Nationality Act of 1965 which lifted racial quotas allowing for more non-European nationals to immigrate to the United States. Additionally, the Handover of Hong Kong motivated many Chinese to immigrate to the U.S. due to the political and economic uncertainties. Today, the vast majority of the neighborhood's population is Asian, with Chinese as the dominant ethnic group. There are still some small Irish enclaves however. Sub-neighborhoods For most of its history, the Sunset existed as a large individual area. In recent years, the neighborhood has been popularly divided into three parts with sometimes vague borders. Inner Sunset The Inner Sunset is bordered by Lincoln Way to the north, 2nd Ave to the east, Quintara Street to the south, and 19th Avenue to the west. This far-east section of the Sunset is located just west of Mount Sutro. The main commercial area is along Irving Street from 5th Avenue to 12th Avenue, and along 9th Avenue from Lincoln Way to Judah Street, much of which is dotted with a variety of restaurants and shops. The Inner Sunset hosts a variety of local businesses, including restaurants, bars, breweries, book stores, bakeries, coffee shops, ice cream parlors, clothes and shoe stores, a tattoo parlor, and a wine bar. All these establishments are clustered around the intersection of 9th Avenue and Irving Street. Food offered by the restaurants located in the Inner Sunset includes pizza, Mexican, Thai, Persian, Korean, Malaysian, Hawaiian, Greek, Ethiopian, Pakistani, Cajun/Creole, Dim Sum, Turkish, Peruvian, Chinese, Vietnamese, California Cuisine, Mediterranean, Indian, Japanese, Vegetarian. Central Sunset The Central Sunset is bounded by Lincoln Way to the north, 19th Avenue to the east, Quintara Street to the south, and Sunset Boulevard to the west. This area is mostly residential with cookie-cutter homes and large lots and a commercial strip along Irving Street from 19th Avenue to 24th Avenue and on Noriega Street from 19th Avenue to 27th Avenue and 30th Avenue to 33rd Avenue. Features of the area include the massive Sunset Reservoir (which takes up eight square blocks between Ortega and Quintara streets and 24th and 28th avenues), which has a small park surrounding its outer rim; Golden Gate Park; the Sunset Recreation Center; and Abraham Lincoln High School. Outer Sunset The Outer Sunset is bordered by Lincoln Way to the north, Sunset Boulevard (between 36th and 37th avenues) to the east, Sloat Boulevard to the south, and Ocean Beach to the west. The primary commercial avenues are Judah, Noriega, and Taraval. The Outer Sunset is the foggiest section in San Francisco due to its close proximity to Ocean Beach. The area's main attractions include the San Francisco Zoo, Golden Gate Park, Ocean Beach, and Lake Merced. Attractions and characteristics The western part of the Sunset borders the cold northern California Pacific Ocean coastline, so it tends to get much of the fog San Francisco is famous for. The Sunset can be foggy and chilly for some days during summer. The Sunset's finest weather is usually from August through December, when regional air patterns transition from onshore to offshore weather and the area is free of fog. Sand carried by Pacific Ocean winds can be found on roadways and driveways within the first five to ten blocks east of Ocean Beach. The Sunset District contains several large park and recreation areas. The San Francisco Zoo is located in the southwestern corner of the neighborhood by Lake Merced, the largest lake within San Francisco. Also within the Lake Merced area are several golf courses: the private Olympic Club and San Francisco Golf Club, and the public TPC Harding Park. Across from Lake Merced is Fort Funston, an old coastal battery, now part of the Golden Gate National Recreation Area. Fort Funston notably has some of the last remnants of the sand dune ecosystem that once covered the entire Sunset District. There is a year-round, Sunday morning farmers' market which is located at 1315 8th Avenue (the parking lot between 8th and 9th Avenues). The market is operated by the Pacific Coast Farmers' Market Association and is sponsored by the Inner Sunset Park Neighbors. The Inner Sunset Farmers' Market offers California-grown produce, fish, eggs, and meat, as well as local food vendors and artisans. Stern Grove, a heavily wooded park and amphitheater located on Sloat Boulevard between 19th and 34th avenues, is known for its annual summer festival. Three parks lie on the far east border of the district: the northernmost is Grand View Park (also referred to as Turtle Hill) a small, elevated park surrounded by 14th and 15th Avenues, as well as Noriega Street; moving south, next is Golden Gate Heights Park, just east of 14th Avenue north of Quintara; and Hawk Hill Park, also east of 14th Avenue at Santiago. These natural areas belong to a remnant ridge-top system and include some of the last-remaining sand-dune communities in the city. Education The San Francisco Unified School District operates public K–12 schools. Educational institutions include the Parnassus campus and medical center of the University of California, San Francisco, located in Inner Sunset; the main campus of San Francisco State University, located in the southwestern corner of the neighborhood across from Lake Merced; Abraham Lincoln High School, located in the center of the Sunset District; St. Ignatius College Preparatory (a private, coeducational school operating in San Francisco since 1855) located since 1969 adjacent to Sunset Boulevard; and Lowell High School, the oldest public high school west of the Mississippi and one of the top performing ones in the United States. Beach culture The strip near the Pacific Ocean has a notable population of surfers who take advantage of the sometimes excellent surf conditions of Ocean Beach. Because of the cold Pacific current that brings ocean water from Alaska, it is usually necessary to wear a wetsuit when surfing at Ocean Beach. Several surf shops can be found near the beach in the Outer Sunset. Several playgrounds are located in the Sunset, including Sunset Playground and Recreation Center, Blue Boat Playground, West Sunset, McCoppin Square, and South Sunset. Current issues The current efforts to develop a comprehensive plan for this section of San Francisco is the Ocean Beach Master Plan (OBMP). The OBMP is an interagency effort to develop a long-term vision for Ocean Beach that will address numerous issues. Climate Like much of the coast of Northern California, Sunset district has a cool summer mediterranean climate, albeit with an unusual annual temperature distribution. The warmest days of the year occur in October and then the coldest nights of the year occur just two months later in December. Its climate is strongly influenced by the Pacific Ocean and therefore has even cooler summers and milder winters than downtown San Francisco. Rainfall follows a seasonal pattern with plentiful precipitation in the winter (almost all of this falling as rain) and extremely dry summers. References Further reading External links Articles related to the Sunset District at FoundSF.org http://outsidelands.org/sunset.php Information from the Western Neighborhoods Project Sunset Neighborhood Beacon Center, youth and family community center Category:Neighborhoods in San Francisco Category:History of San Francisco Category:Chinatowns in the United States Category:Chinese-American culture in San Francisco Category:Populated coastal places in CaliforniaBest answer chosen by InMotion Hosting staff Thanks for posting your question. I'm happy to assist you today. You don't have to worry about deleting a question. Simply log into the support center and mark the question as resolved. If you need further assistance please feel free to contact us.#!/usr/bin/make -f # Copyright (c) TurnKey GNU/Linux - http://www.turnkeylinux.org # # This file is part of Fab # # Fab is free software; you can redistribute it and/or modify it # under the terms of the GNU Affero General Public License as published by
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432, 22680, 275, 8956, 342, 253, 3310, 2426, 15, 187, 38421, 1375, 326, 347, 253, 3522, 323, 253, 28028, 8, 4143, 425, 1096, 13, 30756, 574, 417, 5196, 247, 12611, 1873, 15981, 275, 9008, 323, 253, 4143, 13, 285, 594, 40225, 13, 5675, 20138, 13, 5196, 253, 15981, 5972, 13, 342, 253, 8385, 273, 473, 8, 35, 26558, 15, 1284, 597, 3407, 281, 2278, 253, 5268, 4367, 323, 1016, 273, 253, 1083, 15071, 13, 40225 ]	The facts as presented here are construed accordingly, and they are limited to this motion. I. Henderson's Early History at YAP Henderson was hired by YAP on May 14, 1990, as a Case Manager, by Pahigian with the approval of Weissman and O'Boyle. As one of the first three case managers hired to effectuate the Alternatives to Incarceration contract between the City and State of New York and what was then NCIA, Henderson was involved in establishing the duties and responsibilities of a case manager. Henderson's duties included supervision and management of approximately eight YAP clients. Specifically, his responsibilities included conducting intake and background investigations, developing alternative-to-detention plans to submit to the courts, advocating to the courts for the release of clients from detention into the Program, supporting the children and their families through direct community-based contact and interaction, and regularly submitting progress reports to the courts and other appropriate individuals. On April 11, 1991, Henderson received his first performance review. He received a grade of "outstanding", the highest available, in eight of the ten categories in which he was rated, one "high" grade, and one "normal" grade. Based upon this performance review, Henderson received a pay raise. In October 1991, Pahigian promoted Henderson to the position of Senior Case Manager, with an accompanying pay raise, and that promotion was approved by O'Boyle and Weissman. In addition to his case management duties, Henderson became responsible for assisting in the supervision of three case managers, including providing them with guidance in their casework with clients. On October 15, 1992, Henderson received another performance review. He received exclusively "outstanding" grades and received high praise. Indeed, throughout his tenure as Case Manager and Senior Case Manager, Defendants aver that Henderson was considered by Pahigian, O'Boyle, and Weissman to be an excellent and valued employee. In April 1993, Pahigian resigned, and, as part of YAP's restructuring, Henderson was promoted at the behest of Pahigian and with the efforts of Weissman and O'Boyle on July 1, 1993, to the newly created position of Director of Case Management Services ("DCMS"). As the first person to fill this new position, Henderson was involved in establishing the duties and responsibilities of the DCMS. His duties included direct supervisory responsibility and training of all case management staff, consisting of one Senior Case Manager and five case managers. Henderson had exclusive authority over case management decisions and bore responsibility for maintenance of all client files and records. Because of these additional supervisory responsibilities, Henderson carried a reduced caseload of four clients during his tenure as DCMS. Among his accomplishments during his tenure was to increase significantly the number of referrals to YAP, a goal in light of the fact that the Project had failed to meet its contractual goals during the previous fiscal year. Just before Henderson assumed the position of DCMS, following Pahigian's resignation in April, YAP operated until August 20, 1993, without a Project Director until Wong filled the vacancy. During this time, Henderson was the highest-ranking case management employee at YAP and had extensive latitude and autonomy. 695 II. The Automobile Incident Defendants allege that the relationship between Wong and Henderson began on poor footing, and that almost instantly upon taking over YAP, Wong experienced resistance from Henderson in accepting her supervision and authority. Their first exchange, besides mere pleasantries, consisted of an encounter in which Henderson objected to and challenged Wong's enforcement of a YAP policy on employee use of automobiles leased by the Project. Henderson asserts that the nature of this interaction was professional, not personally antagonistic. The details of the interaction are as follows. Case managers were allowed to use leased cars available to YAP as needed, provided use had been approved by either the Project Director or the Assistant Project Director. Because there was no Project Director at the time a memorandum was issued regarding this policy, Henderson, as DCMS, was allowed to approve the case managers' use of the cars. Several days after Wong began as Project Director at YAP, she issued a memorandum reiterating that only she or the Assistant Project Director could approve case managers' use of cars. Henderson's access to the cars remained unchanged, but he did confront Wong after learning of her memorandum, dismayed at the fact that she had made the change without first consulting with him. Defendants assert that this confrontation began a strained relationship between Henderson and Wong, marked by Henderson's refusal to adapt to Wong's different approach to management of YAP and to her tempering of his previous authority and control. Henderson states that the situation was relatively cordial once the misunderstanding had been worked out, and that there were no lingering bad feelings between him and Wong. III. The Crossroads Incident On October 15, 1993, Henderson overheard a Crossroads client, Simone, an African-American woman who was engaged in cleaning a bathroom at the YAP offices on the CCA premises, complaining that she had been compelled by the Crossroad program to do that work. Crossroads had only recently required its clients to clean the YAP bathrooms, and Simone informed Henderson of that fact. Also recently, Darrel, an African-American man, had been replaced as CCA's maintenance worker by John Clohessy ("Clohessy"), a white man. Henderson was dismayed upon learning of Crossroads' new policy. He asserts that there were two sources of his dismay. First, Henderson states, he believed that the practice of compelling Crossroads clients to clean CCA bathrooms was discriminatory and akin to slavery, because the Crossroads clients were exclusively black and Latino, because the new cleaning policy had been implemented at the same time that Clohessy had replaced Darrel, and because Clohessy had been hired to supervise the Crossroads clients, though Darrel had cleaned the CCA bathrooms without assistance. Second, Henderson states, he was bothered by the appearances presented by the Crossroads policy, believing them antithetical to the philosophy of CCA. Henderson asked Simone to stop cleaning the YAP bathrooms and advised her that he would speak to someone about the new requirement. When Bloomfield learned that day of Henderson's actions, he asked O'Boyle to call a meeting among the three of them. Bloomfield argued to O'Boyle that it was improper and potentially damaging from a treatment perspective for Henderson to undermine the authority of the Crossroads treatment team by giving any instructions directly to Crossroads clients. Bloomfield told O'Boyle that Henderson should have raised any concerns or objections with Bloomfield or another Crossroad employee. O'Boyle asked Henderson to come to her office, and Bloomfield reiterated his objections to Henderson's behavior. Henderson expressed his objection to the new cleaning policy as discriminatory, degrading to the clients, and contrary to the goals of CCA. Henderson further stated that he believed an improper appearance was presented by having the Crossroads clients cleaning, because of the stereotypes associated with that work, and in light of the fact that all of the Crossroads clients were all black or Latino. Bloomfield emphasized that all Crossroads 696 clients were required to undertake various responsibilities in order to instill a sense of ownership of the community as part of the Crossroads treatment program, and that this was a widespread therapeutic philosophy in other, similar treatment communities. Bloomfield stressed that the client responsibilities program had been instituted by Donna Harris, the Crossroads Director of Treatment, who is black. Henderson alleges that at the meeting, Bloomfield suggested that Henderson himself was a racist because Henderson had objected to the policy only because all of the Crossroads clients were members of minority groups and that Henderson would not have reacted to their cleaning the YAP bathrooms had they been white. Henderson also alleges that during the meeting, O'Boyle defended the policy in part because she claimed the Crossroads clients enjoyed cleaning. After the meeting, Crossroads no longer required its clients to clean the bathrooms on the YAP side of the CCA facility. Henderson states that this change in policy constituted a compromise to which O'Boyle and Bloomfield reluctantly agreed. Defendants state that they believed that Henderson had raised a valid point regarding the possibility of misinterpretation of the client responsibilities by those unfamiliar with the concept of rehabilitative treatment, and they thus decided to discontinue cleaning on the YAP side of the CCA facility, while continuing it on the Crossroads side. Subsequent to this meeting, Bloomfield and O'Boyle never discussed the issue again with Henderson. Defendants assert that neither Bloomfield nor O'Boyle discussed the incident with Wong prior to Henderson's discharge, believing the situation to be resolved. Henderson asserts that the incident became the focus of substantial discussion among Bloomfield, O'Boyle, Weissman, and the Crossroads staff over the next several weeks, and that his actions were cast in a negative light in the course of those discussions. IV. The File Review Because YAP contracts with the City of New York, the Project is subject to periodic site visits from City contractors monitoring YAP's compliance with the terms of the contract. The City monitors were scheduled to conduct a site visit of YAP on October 26, 1993. These site visits had occurred regularly during Pahigian's tenure as Project Director, but the October 26, 1993, visit was to be the first following Wong's employment as Project Director. Typically during these site visits, monitors conducted an audit of the case management files to assure that the clients were being adequately supervised upon release from detention in accordance with the contract terms. Defendants state that as the date for the monitors' visit neared, Henderson had not conducted a preliminary file inspection in preparation for the visit, and so Wong, growing anxious, conducted the inspection herself, with the assistance of O'Boyle. As they began to review the client files for each of the case managers, Wong
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14897, 907, 62, 281, 271, 5368, 2898, 13, 352, 310, 625, 11638, 281, 823, 253, 747, 9503, 281, 253, 5447, 949, 253, 2914, 14, 423, 685, 407, 2057, 13542, 6240 ]	get some basic Role management happening. When roles are used to enforce access restrictions within our application, they are basically hard-coded, usually via the [Authorize] attribute. Giving application administrators the ability to add, modify, and delete roles is of limited use if they cannot also modify the access permissions afforded by [Authorize] . The above notwithstanding, sometimes we might wish to add some properties to our basic roles, such as a brief description. In this post we will see how we can extend the IdentityRole class, by adding an additional property. We will also add the basic ability to create, edit, and delete roles, and what all is involved with that, despite the fact that any advantage to adding or removing roles is limited by the hard-coded [Authorize] permissions within our application. If you are using the Identity 2.0 Framework: This article focuses on customizing and modifying version 1.0 of the ASP.NET Identity framework. If you are using the recently released version 2.0, this code in this article won't work. For more information on working with Identity 2.0, see Many of the customizations implemented in this article are included "in the box" with the Identity Samples project. I discuss extending and customizing IdentityUser and IdentityRole in Identity 2.0 in a new article,ASP.NET Identity 2.0: Customizing Users and Roles If you are using the Identity 1.0 Framework: UPDATE: 2/24/2014 - Thanks to Code Project user Budoray for catching some typos in the code. The EditRoleViewModel and RoleViewModel classes were referenced incorrectly in a number of places, preventing the project from building properly. Fixed! We have laid the groundwork for what we will be doing in the previous article on Extending Identity Accounts, so we will clone that project and build on top of the work already done. In that project, we: Created a restricted, internal access MVC site. Removed extraneous code related to social media account log-ins, and other features we don't need. Extended the IdentityUser class to include some additional properties, such as first/last names, and email addresses. Added the ability to assign users to pre-defined roles which govern access to various functionality within our application. In the original project, I had left all of the Identity-related models in the single file created with the default project template. Before getting started here, I pulled each class out into its own code file. Also, we will be re-building our database and migrations. After cloning the source, I deleted the existing Migration (not the Migrations folder, just the Migration file within named 201311110510410_Init.cs. We will keep the Migrations/Configuration.cs file as we will be building out on that as we go. Previously, we were able to define the model class ApplicationUser, which extended the Identity class IdentityUser, run EF Migrations, and with relative ease swap it with IdentityUser in all the areas of our application which previously consumed IdentityUser. Things are not so simple, however, when it comes to extending IdentityRole. IdentityRole forms a core component in the authorization mechanism for an ASP.NET application. For this reason, we might expect the Identity system to be resistant to casual modification of the IdentityRole class itself, and perhaps equally importantly, the manner in which the rest of the identity system accepts derivatives. So we need to find a way to accomplish what we wish to achieve without compromising the integrity of the Identity mechanism, or those components downstream which may depend upon an instance of IdentityRole to get the job done. First off, let's take a look at our existing ApplicationDbContext class: The ApplicationDbContext Class: In the above, we can see we are inheriting from the class IdentityDbContext<TUser>, which allows us to specify a custom type, so long as that type is derived from IdentityUser. So it appears that the Identity system generally provides a built-in mechanism for extending IdentityUser. Is there a similar path for extending IdentityRole? Turns out there is. Sort of. As we can see, we have created a derived class and implemented a simple new Description property, along with a new overridden constructor. Next, we need modify our ApplicationDbContext so that, when we run EF Migrations, our database will reflect the proper modeling. Open the ApplicationDbContext class, and add the following override for the OnModelCreating method: Add These Namespaces to the Top of your Code File: using Microsoft.AspNet.Identity.EntityFramework; using Microsoft.AspNet.Identity; using System.ComponentModel.DataAnnotations; using System.Collections.Generic; using System.Data.Entity; using System; using System.Data.Entity.Infrastructure; using System.Data.Entity.ModelConfiguration; using System.Data.Entity.ModelConfiguration.Configuration; using System.Data.Entity.Validation; using System.Globalization; using System.Linq; using System.Linq.Expressions; using System.Reflection; using System.Runtime.CompilerServices; Then add the following Code to the ApplicationDbContext class: NOTE: This code is dense and a little messy. Don't work about understanding the details here - just take a high level view and try to grasp the overall idea of how this code is mapping our code objects to database tables. In particular, the manner in which it models the foreign key relationships between tables. In the above, we are basically telling Entity Framework how to model our inheritance structure into the database. We can, however, tell EF to model our database in such a way that both of our derived classes can also utilize the same tables, and in fact extend them to include our custom fields. Notice how, in the code above, we first tell the modelBuilder to point the IdentityUser class at the table "AspNetUsers", and then also tell it to point ApplicationUser at the same table? We do the same thing later with ApplicationRole. As you can see, there is actually no getting away from either the IdentityUser or IdentityRole classes - both are used by the Identity system under the covers. We are simply taking advantage of polymorphism such that, at the level of our application, we are able to use our derived classes, while down below, Identity recognizes them as their base implementations. We will see how this affects our application shortly. Now, however, we can replace IdentityRole with ApplicationRole in most of the rest of our application, and begin using our new Description property. We will begin with our IdentityManager class. I did a little refactoring here while I was at it, so if you are following along, this code will look a little different than what you will find in the original project. Just paste this code in (but make sure your namespaces match!). I also added a few new using's at the top of the code file. We will also want to update our AddUsersAndRoles() method, which is called by the Seed() method in the Configuration file for EF Migrations. We want to seed the database with Roles which use our new extended properties: All we really did here was pass an additional argument to the CreateRole() method, such the the seed roles will exhibit our new property. Now, we need to make a few adjustments to our AccountController, View Models, and Views. In the previous article, we created a SelectRoleEditorViewModel which accepted an instance of IdentityRole as a constructor argument. We need to modify the code here in order to accommodate any new properties we added when we extended IdentityRole. For our example, we just added a single new property, so this is pretty painless: Recall that, in order to display the list of roles with checkboxes as an HTML form from which we can return the selection choices made by the user, we needed to define an EditorViewModel.cshtml file which corresponded to our EditorViewModel class. In Views/Shared/EditorViewModels open SelectRoleEditorViewModel.cshtml and make the following changes: To this point, we actually only have one View which displays our Roles - the UserRoles view, where we assign users to one or more Roles within our application. Once again, we really just need to add a table Header element to represent our new Description property: The Updated UserRoles View: Here is where you may want to think things through a little bit. Consider - the main reason for utilizing Roles within an ASP.NET application is to manage authorization. We do this by hard-coding access permissions to controllers and/or specific methods through the [Authorize] attribute. If we make roles createable/editable/deletable, what can possibly go wrong? Well, a lot. First off, if we deploy our application, then add a role, we really have no way to make use of the new role with respect to the security concerns listed above, without re-compiling and re-deploying our application after adding the new role to whichever methods we hope to secure with it. The same is true if we change a role name, or worse, delete a role. In fact, an ambitious admin user could lock themselves out of the application altogether! However, there are some cases where we might want to have this functionality anyway. If, for example, you are the developer, and you add some new role permissions via [Authorize] to an existing application, it is more convenient to add the new roles to the database through the front-end than by either manually adding
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271, 6485, 5370, 15, 187, 187, 6872, 10071, 1119, 1905, 275, 253, 3000, 273, 581, 5370, 382, 1905, 773, 66, 2581, 35247, 24492, 668, 327, 253, 4310, 457, 84, 629, 670, 253, 2687, 457, 84, 1966, 9099, 15, 1621, 581, 3260, 849, 1142, 952, 651, 320, 258, 15172, 13, 285, 627, 369, 1652, 9008, 13, 390, 1014, 2130, 2659, 13, 323, 501, 3592, 1981 ]	it harder for them to make their living on the coast. Residents of Tragadi Bandar claim in a lawsuit filed April 23 in U.S. federal court in Washington, D.C., that warm water discharged by the Tata plant has driven fish away from the intertidal zone, where the Waghers used to practice pagadiya, a traditional method of setting up nets and harvesting the fish at low tide. The returns from boat fishing, which takes place farther from shore, have also fallen off. “You see this produce here?” says Jam, sweeping his arm across a view of his bandar, one of several fishing settlements along the gulf. Burlap bags stuffed with dried Bombay duck sit on the sand waiting for market. “We used to get this much business in one day. Now it takes 15.” Yunus Suleman Gadh and other fisherfolk on Kutadi Bandar discuss how the Tata plant has harmed both their livelihoods and their health. Sami Siva / International Consortium of Investigative Journalists Jam and his neighbors are among the uncounted: people the World Bank Group and its borrowers have ignored in their push to create dams, power plants and other projects. The global institution’s two main lenders — the World Bank, which lends to governments, and the International Finance Corporation, which lends to corporations such as Tata — have repeatedly failed to make sure people harmed by big projects get counted, an investigation by the International Consortium of Investigative Journalists has found. Both lenders have detailed policies that require that their borrowers identify people whose homes or land will be lost or livelihoods will be damaged as a result of the projects they finance. When “project-affected people” are identified, borrowers must resettle them into new homes or help restore their livelihoods. But if people don’t get counted, they’re unlikely to get help from the lenders and their borrowers in putting their lives back together. In some cases, the IFC and the World Bank have declined to count entire populations that claim they’ve been harmed by projects backed by the lenders. In Kenya and Ethiopia, indigenous groups claim that World Bank cash bankrolled mass evictions that targeted them for threats, violence or arbitrary arrests. The World Bank denies its money was used for these evictions. What Is The World Bank? The World Bank Group is the globe’s most prestigious development lender, bankrolling hundreds of government projects each year in pursuit of its high-minded mission: to combat the scourge of poverty by backing new transit systems, power plants, dams and other projects it believes will help boost the fortunes of poor people. Read more » World Bank Group IBRD IDA IFC International Bank for Reconstruction and Development, one of the two lending arms traditionally considered to be the World Bank International Development Association, one of the two lending arms traditionally considered to be the World Bank International Finance Corporation, the World Bank’s private-lending arm Typically lends to middle-income governments, also some creditworthy low-income countries Typically lends to low-income governments Typically lends to private firms in developing (low- to middle-income) countries Founded in 1944 Founded in 1960 Founded in 1956 FY 2014 commitments $18.6 billion FY 2014 commitments $22.2 billion FY 2014 commitments $17.3 billionn Lends at market rate Guarantees loans Lends at low interest rate Lends at market rate Guarantees loans Invests in private companies 1. IBRD International Bank for Reconstruction and Development, one of the two lending arms traditionally considered to be the World Bank Typically lends to middle-income governments, also some creditworthy low-income countries Founded in 1944 FY 2014 commitments $18.6 billion Lends at market rate Guarantees loans 2. IDA International Development Association, one of the two lending arms traditionally considered to be the World Bank Typically lends to low-income governments Founded in 1960 FY 2014 commitments $22.2 billion Lends at low interest rate 3. IFC International Finance Corporation, the World Bank's private lending arm Typically lends to private firms in developing (low- to middle-income) countries Founded in 1956 FY 2014 commitments $17.3 billion Lends at market rate Guarantees loans Invests in private companies World Bank Annual Report Sources: Congressional Research Service In other cases, the World Bank has acknowledged that large numbers of people would be harmed by development initiatives, but allowed its borrowers to underestimate the real number. A 2012 internal review of nine World Bank-supported projects found that the number of affected people turned out to be, on average, 32 percent higher than the figure reported by the bank before approving the initiatives, understating the number of people affected by the nine projects by 77,500. This echoed a broader internal review in 1994, which looked at 192 projects and found that the real number of affected people averaged 47 percent higher than previously estimated. In March, a World Bank spokesman acknowledged that the bank-financed Nam Theun 2 dam in Laos has physically displaced or economically affected more than 75,000 villagers — a 50 percent increase over the 50,000 figure that the bank had reported before it approved the project in 2005. Independent researchers who have studied the project estimate that the number of people who have been harmed by the dam’s construction is larger than even bank’s updated number — reaching as high as 130,000 to 150,000. Bruce Shoemaker, a researcher on natural resources issues who worked on the independent review, says villagers downstream from the dam have suffered a drop in wild fish catches, excessive flooding of their rice fields and other impacts on their livelihoods. The failure by World Bank and Laotian officials to recognize the dam’s full effects on people above and below the dam means that the compensation offered to farmers and fisherfolk “didn’t come close to making up for their losses,” Shoemaker says. World Bank officials say they disagree with the larger estimate reached by Shoemaker and his co-researchers. “We are always willing to consider independent studies that focus on our projects,” David Theis, a bank spokesman, said in a written statement. “In this case, our extensive and detailed research and analysis has yielded different facts, which we stand by.” The bank says most people affected by Nam Theun 2 are better off than they were before, with surveys showing many families having more savings and assets and fewer underweight children. The bank says the increase in the numbers of people identified as being affected by the dam came because the project’s managers used a broader definition of affected households. In other cases, bank officials have attributed shifting numbers for people harmed by projects to later expansions in projects’ size or to population growth during projects’ long time windows. Theis said that despite the complex challenges of keeping track of people affected by development, “we are going to be extremely vigilant about our work in this area. When our work does involve relocation, we will do so as long as we can improve or at least restore people’s incomes and living conditions.” Wagher fishermen head into the gulf one afternoon. The water discharged by the Tata power plant is often hotter than the seawater, altering the marine ecosystem, an independent fact-finding team found. Sami Siva / International Consortium of Investigative Journalists Early Warning The problem of undercounting resonates in the Indian state of Gujarat, the site of a mammoth debacle that was supposed to transform the World Bank’s approach to development and displacement. In 1985, the bank pledged $450 million to finance the Sardar Sarovar dam and canal, the keystone of an effort to turn the Narmada River into a series of reservoirs that would serve the state’s most drought-prone regions. The bank estimated in 1987 that 60,000 people would be affected by the project. By 2000, the World Commission on Dams, a study group co-sponsored by the World Bank, put the figure at more than 200,000. Current estimates from NGOs monitoring the project indicate more than 250,000 will be impacted by the dam, which is in now in its final stages of construction. Many of the displaced, like the Wagher fishing families, had no title to the land they occupied. World Bank policies explicitly state that residents without title still qualify for compensation and resettlement assistance. Planning for Sardar Sarovar began with an “elaborate Government pantomime of conducting studies to estimate the actual project costs and the impact it would have on people and the environment,” the famed Indian novelist and activist Arundhati Roy later wrote. “The World Bank participated wholeheartedly in the charade — occasionally it beetled its brows and raised feeble requests for more information on issues like the resettlement and rehabilitation of what it calls ‘PAPs’ — Project Affected Persons. (They help, these acronyms — they manage to mutate muscle and blood into cold statistics. PAPs soon cease to be people.) The merest of crumbs satisfied the Bank and it proceeded with the project.” Resistance was fierce. Protesters blocked roads and barred government officials from their villages. Some pledged to drown rather than leave their land. Police met Gandhi-style nonviolence with beatings and arrests. After activists launched a hunger strike, the World Bank agreed to an independent review by an expert panel. These experts found — in the words of one panelist — “a rather terrifying ignorance” on the bank’s part about the dam’s human consequences. No one knew how many people would be ousted, and there was little preparation, or even available land, for resettling
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Why did they stay and get sick? Lilith walked back to the settlement, a long crude basket filled with breadnuts on her back. She found the male and female ministering to their ooloi holding it between them and entangling its head and body tentacles with their own. Wherever the three touched, tentacles joined them. It was an intimate, vulnerable position, and other ooloi lounged nearby, guarding without seeming to guard. There were also a few humans watching. Lilith looked around the settlement, wondering how many of the humans not present would not come back from their day of wandering or food gathering. Did those who left come together on some other part of the island? Had they built a shelter? Were they building a boat? A wild thought struck her: What if they were right? What if they somehow were on Earth? What if it were possible to row a boat to freedom? What if, in spite of all she had seen and felt, this was some kind of hoax? How would it be perpetrated? _Why_ would it be perpetrated? Why would the Oankali go to so much trouble? No. She did not understand why the Oankali had done some of what they had done, but she believed the basics. The ship. The Earth, waiting to be recolonized by its people. The Oankali's price for saving the few remaining fragments of humanity. But more people were leaving the settlement. Where were they? What if—The thought would not let her alone no matter what facts she felt she knew. _What if the others were right?_ Where had the doubt come from? That evening as she brought in a load of firewood, Tate blocked her path. "Curt and Celene are gone," she said quietly. "Celene let it slip to me that they were leaving." "I'm surprised it took them so long." "I'm surprised Curt didn't brain an Oankali before he left." Nodding in agreement, Lilith stepped around her and put down her load of wood. Tate followed and again planted herself in Lilith's path. "What?" Lilith asked. "We're going too. Tonight." She kept her voice very low—though no doubt more than one Oankali heard her. "Where?" "We don't know. Either we'll find the others or we won't. We'll find something—or make something." "Just the two of you?" "Four of us. Maybe more." Lilith frowned, not knowing how to feel. She and Tate had become friends. Wherever Tate was going, she would not escape. If she did not injure herself or anyone else, she would probably be back. "Listen," Tate said, "I'm not just telling you for the hell of it. We want you to go with us." Lilith steered her away from the center of the camp. The Oankali would hear no matter what they did, but there was no need to involve other humans. "Gabe has already talked to Joe," Tate said. "We want—" "Gabe what!" "Shut up! You want to tell everyone? Joe said he'd go. Now what about you?" Lilith stared at her hostilely. "What about me?" "I need to know now. Gabe wants to leave soon." "If I leave with you, we'll leave after breakfast tomorrow morning." Tate, being Tate, said nothing. She smiled. "I didn't say I was going. All I mean is that there's no reason to sneak away in the night and step on a coral snake or something. It's pitch black out there at night." "Gabe thinks we'll have more time before they discover we're gone." "Where's his mind—and yours? Leave tonight and they'll notice you're gone by tomorrow morning—if you don't wake everyone on your way out by tripping over something or someone. Leave tomorrow morning and they won't notice you're gone until tomorrow night at dinner." She shook her head. "Not that they'll care. They haven't so far. But if you want to slip away, at least do it in a way that will give you a chance to find shelter before nightfall—or in case it rains." "When it rains," Tate said. "It always rains sooner or later. We thought... maybe once we were clear of this place, we'd cross the river, head north, keep heading north until we found a dryer, cooler climate." "If we are on Earth, Tate, considering what was done to Earth and especially to the northern hemisphere, south would be a better direction." Tate shrugged. "You don't get a vote unless you come with us." "I'll talk to Joe." "But—" "And you ought to get Gabe to help you with your acting. I haven't said a thing you and Gabe hadn't already thought of. Neither of you is stupid. And you, at least, are no good at bullshitting people." Characteristically, Tate laughed. "I used to be." She sobered. "Okay, yeah. We've pretty much worked out the best way of doing it—tomorrow morning and south and with someone who probably knows how to stay alive in this country better than anyone but the Oankali." There was a silence. "We really are on an island, you know," Lilith said. "No, I don't _know_ ," Tate answered. "But I'm willing to take your word for it. We'll have to cross the river." "And in spite of what we see on what seems to be the other side, I believe we'll find a wall over there." "In spite of the sun, the moon and the stars? In spite of the rain and the trees that have obviously been here for hundreds of years?" Lilith sighed. "Yes." "All because the Oankali said so." "And because of what I saw and felt before I Awoke you." "What the Oankali let you see and made you feel. You wouldn't believe some of the stuff Kahguyaht has made me feel." "Wouldn't I?" "I mean, you can't trust what they do to your senses!" "I knew Nikanj when it was too young to do anything to my senses without my being aware of it." Tate looked away, stared toward the river where the glint of water could still be seen. The sun—artificial or real—had not quite vanished and the river looked browner than ever. "Look," she said, "I don't mean anything by this, but I have to say it. You and Nikanj..." She let her voice die, abruptly looked at Lilith as though demanding a response. "Well?" "Well, what?" "You're closer to him—to it—than we are to Kahguyaht. You..." Lilith stared at her silently. "Hell, all I mean is, if you won't go with us, don't try to stop us." "Has anyone tried to stop anyone from leaving?" "Just don't say anything. That's all." "Maybe you are stupid," Lilith said softly. Tate looked away again and shrugged. "I promised Gabe I'd get you to promise." "Why?" "He thinks if you give your word, you'll keep it." "Otherwise, I'll run and tell, right?" "I'm beginning not to care what you do." Lilith shrugged, turned and started back toward camp. It seemed to take Tate several seconds to see that she meant it. Then she ran after Lilith, pulled her back away from the camp. "All right, I'm sorry you're insulted," Tate rasped. "Now are you going or aren't you?" "You know the breadnut tree up the bank—the big one?" "Yes?" "If we're going, we'll meet you there after breakfast tomorrow." "We won't wait long." "Okay." Lilith turned and walked back to camp. How many Oankali had heard the exchange? One? A few? All of them? No matter. Nikanj would know in minutes. So it would have time to send for Ahajas and Dichaan. It would not have to sit and go catatonic like the others. In fact, she still wondered why the others had not done it. Surely they had known that their chosen humans were leaving. Kahguyaht would know. What would it do? Something occurred to her suddenly—a memory of tribal people sending their sons out to live for a while alone in the forest or desert or whatever as a test of manhood. Boys of a certain age who had been taught how to live in the environment were sent out to prove what they had learned. Was that it? Train the humans in the basics, then let them go out on their own when they were ready? Then why the catatonic ooloi? "Lilith
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15293, 43, 14, 316, 582, 519, 25667, 64, 187, 187, 5279, 314, 21802, 281, 11377, 275, 33563, 15, 26775, 17689, 476, 671, 1599, 346, 1171, 390 ]	High blood pressure; the condition that occurs as a result of high blood pressure. _Some over-the-counter cough, cold, and allergy medicines tend to cause elevated blood pressure, and include a warning that they may be hazardous to those suffering from HYPERTENSION._ hypocrite _(HIP-uh-krit), noun_ A person pretending to be something he or she is not, or pretending, for the sake of appearance, to have high moral beliefs; a person who does not act according to espoused beliefs. _In Marilyn's view, a marriage counselor who advised others to live up to the ideal of fidelity but who cheated on his own wife was the worst kind of HYPOCRITE._ ignoble _(ig-NO-bull), adjective_ Dishonorable in nature. In contrast with ignominious (see below), ignoble carries the sense of baseness or lowness. _Peter's IGNOBLE aims were well known to all in the room._ illicit _(ih-LISS-it), adjective_ Illegal or morally unjustifiable. Illicit refers to something not sanctioned by custom or law. _We all know now that the money was acquired through ILLICIT means, don't we?_ imbecility _(im-buh-SILL-ih-tee), noun_ Foolishness; simplemindedness. _Although he lamented the IMBECILITY of mainstream television, Arnie was not above an occasional viewing of American Gladiators or Geraldo._ improvident _(ihm-PRAHV-ih-dent), adjective_ Describes someone who does not plan well for the future or one who acts without thinking. _It was cute when he was younger, but now Mike's IMPROVIDENT behavior just makes him look like a total loser._ inane _(in-ANE), adjective_ Pointless or lacking in substance. Something that is inane is vacuous. _Among other INANE suggestions, Jeff proposed painting the lunchroom in a polkadot pattern._ indict _(in-DITE), verb_ To charge formally with a crime or offense. (See, for comparison, the entry for indite.) _Rumors that Mr. Brown would soon be INDICTED for his part in the scandal swept the city._ indiscreet _(in-dih-SKREET), adjective_ Lacking good judgment and prudence; apt to run one's mouth about things that others would like left private. _Don't get alcohol near Melanie. It makes her go from prudent to INDISCREET in less than sixty seconds!_ infernal _(in-FER-nul), adjective_ Fiendish; devilish. Infernal means, literally, "of or pertaining to hell." It is often used as a mild expletive. _This INFERNAL copier keeps breaking down!_ infidelity _(in-fi-DEL-ih-tee) noun_ The quality or act of having been untrue or inconsistent with a (often implied) standard. Infidelity is often used to describe extramarital affairs. _Although Gwen suspected her husband of INFIDELITY, she had not come across any tangible proof._ influenza _(in-floo-EN-zuh), noun_ A contagious respiratory virus characterized by inflammation of the mucous membrane, fever, prostration, aches, and pains. _David was still weak from his bout with INFLUENZA._ ingrate _(IN-grate), noun_ An ungrateful person. A person who does not show the proper respect or gratitude toward someone who has provided help might be called an ingrate. _He lived with us for six months, but that INGRATE Ralph hasn't even written in over two years._ iniquity _(ih-NIK-wih-tee), noun_ Injustice or immoral action. Iniquity derives from the Latin for "unfairness." _The many INIQUITIES suffered by American Indians at the hands of government authorities is only now being widely acknowledged._ insidious _(in-SID-ee-uss), adjective_ Designed to entrap; happening or spreading harmfully but subtly; stealthily and seductively treacherous. _Mark's chess games were full of INSIDIOUS traps meant to lull his opponent into a sense of complacency._ insipid _(in-SIP-id), adjective_ Lacking in vigor; dull. Insipid (usually applied to bland ideas, personalities, or works of art) derives from the Latin for "without taste." _In Frank's opinion, the novel's plot was INSIPID and left much to be desired._ insolent _(IN-suh-lnt), adjective_ Rude and arrogant. That which is insulting or disrespectful (especially speech) could be considered _insolent_. _Her INSOLENT retorts to Joan's well-intentioned queries stunned the dinner party._ insubordinate _(in-suh-BOR-din-it), adjective_ Failing to accept or obey proper authority. In the military, an enlisted man who insults an officer could be accused of an insubordinate act. _Frank, not eager to be branded INSUBORDINATE, did his best to carry out the colonel's strange orders._ irascible _(ih-RASS-uh-bul), adjective_ Easily angered. Those who are prone to fits of temper are irascible. _Sebastian, an IRASCIBLE man, did his best to put on a show of conviviality when he visited his in-laws, most of whom irritated him._ jaded _(JAY-dud), adjective_ Worn out; dulled or satiated due to overindulgence. _Her parents thought that providing Tracy with everything her heart desired as a child would make her a happy person, but she grew up to be a JADED and selfish woman._ jaundice _(JON-diss), noun_ A yellowish tint to the body's skin, fluids, and tissues as a result of the buildup of excessive bile; also, a biased, hostile attitude. _The cosmetics saleswoman tried to convince her that the makeover had given her a tanned appearance, but Shawna worried that she looked like she had JAUNDICE._ lacerated _(LASS-uh-ray-tud), adjective_ Cut, torn, ripped, or mangled. _Because I LACERATED my finger with the scissors while I was on the job, I was eligible to file a workers' compensation claim._ lackadaisical _(lack-uh-DAZE-ih-kul), adjective_ Lacking spirit or energy; languid. _I was feeling rather LACKADAISICAL last Sunday, so I stayed in bed all day and watched football games instead of mowing the lawn._ lackluster _(LACK-lus-tur), adjective_ Dull; not shiny or brilliant. _Wanda's LACKLUSTER performance as Hedda Gabler led one critic to remark that she probably had a long career ahead of her in the theater—as a stage weight._ libel _(LIE-bull), noun_ A written, printed, or pictorial statement or assertion that is unjustly negative, defaming, or hurtful to one's character and reputation. _Several celebrities have sued the supermarket tabloid for LIBEL, but the parade of lurid and preposterous headlines has continued unabated._ libertine _(LIB-ur-teen), noun_ One who lives life unconcerned and unrestrained by popular convention or morality; a promiscuous person, especially a man. _Presumably because he is divorced, my elderly grandmother refers to my fiance Eric as "that LIBERTINE," but everyone else in my family thinks he's wonderful._ licentious _(lie-SENN-shuss), adjective_ Having little or no moral restraint, especially with regard to sex. _After months of watching Gary leave the nightclub with one woman after another, Paul finally decided to tell Maureen of her husband's LICENTIOUS behavior._ lip-sync _(LIP-sink), verb_ To simulate a live singing performance by mouthing along to a record. _It is common these days for recording artists to LIP-SYNC for the bulk of a " live" concert._ litigious _(lih-TIJ-us), adjective_ Overly inclined to engage in lawsuits. Litigious can also mean "of or
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24, 62, 527, 311, 478, 2610, 60, 18, 13, 19, 14, 67, 62, 16573, 11975, 14, 20, 13, 1010, 14, 69, 6035, 28, 187, 22, 14, 4040, 14, 26, 14, 47257, 14, 22, 14, 19304, 14, 740, 14, 13006, 14, 18, 13, 21, 13, 22, 13, 1012, 14, 49513, 8724, 14, 20, 41, 13, 1010, 41, 14, 1004, 554, 2610, 60, 20, 7096, 19, 89, 1438, 89, 19, 13, 21, 7096, 19, 89, 1438, 89, 19, 27, 23, 13, 24, 62, 527, 311, 478, 2610, 60, 18, 13, 19, 14, 67, 62, 16573, 11975, 14, 20, 13, 1010, 14, 69, 6035, 28, 187, 22, 14, 4040, 14, 740, 14, 47257, 14, 22, 14, 19304, 14, 18, 13, 21, 13, 22, 13, 1012, 14, 49513 ]	-3,15-dione; 10-(benzyloxy)-5-ethyl-9-fluoro-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9,10-difluoro-3,15-dioxo-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-5-yl 2-aminoacetate; 5-ethyl-9,10-difluoro-3,15-dioxo-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-5-yl 3-aminopropanoate; 2,9-diethyl-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 9-ethyl-9-hydroxy-2-methyl-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 2-benzyl-9-ethyl-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 2-benzyl-9-ethyl-5-fluoro-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; (+)-5-ethyl-9,10-difluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; (+)-1-[9-chloro-5-ethyl-5-hydroxy-10-methyl-3,15-dioxo-4,5,13,15-tetrahydro1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-12-ylmethyl]-4-methylhexahydropyridine; or a pharmaceutically acceptable salt of the latter. The invention more particularly relates to the following compounds corresponding to the formula (HCPT): 5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5,12-diethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline3,15-dione; 8-ethyl-8-hydroxy-2,3,8,9,12,15-hexahydro-10H,13H-[1,4]dioxino[2,3-g]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-10,13-dione; 10-(benzyloxy)-5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 11-[(dimethylamino)methyl]-5-ethyl-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 9-chloro-5-ethyl-5-hydroxy-10-methyl-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9,10-difluoro-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 7-ethyl-7-hydroxy-7,8,11,14-tetrahydro-9H,12M-[1,3]dioxolo[4,5-g]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-9,12-dione; 9-chloro-5-ethyl-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 9,11-dichloro-5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5-hydroxy-10-methyl-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-10-fluoro-5-hydroxy-1,4,5,13-tetra
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273, 495, 15, 24, 1202, 2592, 5, 281, 721, 15, 21, 1202, 2592, 5, 323, 247, 49199, 757, 7602, 1673, 835, 253, 5791, 1930, 273, 253, 7592, 310, 4886, 1977, 432, 441, 13, 5727, 642, 9510, 310, 6786, 672, 253, 861, 273, 253, 7602, 1673, 310, 28483, 15 ]	Gas: Detection around M Dwarf TWA 7' --- Introduction {#sect:intro} ============ Planetesimal belts, also known as debris disks, are extrasolar Kuiper and asteroid belt analogues, detected around a significant fraction of nearby, main-sequence solar-type (FGK) and A stars [for a review, see e.g. @Hughes2018; @Wyatt2018]. Detectable belts are collision-dominated environments, where the mass of the observed dust and larger planetesimals in a so-called collisional cascade depletes over time [as observed, e.g. @Wyatt2007b; @Holland2017; @Sibthorpe2018]. To date, 19 of these belts have been detected in one or several gas tracers. Detection of gas in planetesimal belts has the potential to inform us about exocometary compositions [@Matra2017b; @Matra2018a], particularly during the $\sim$10-100 Myr period when terrestrial planet formation is still ongoing, and volatile delivery events through exocomets may be commonplace [e.g. @Morbidelli2012]. CO dominates the number of detections (17/19), in part thanks to the unprecedented sensitivity of the Atacama Large Millimeter/submillimeter Array (ALMA). For many systems, it remains debated whether the gas is primordial or secondary in origin, where primordial gas is a long-lived remnant of the protoplanetary disk [@Kospal2013], whereas secondary gas is second-generation like the dust, produced by exocometary gas release [e.g. @Zuckerman2012; @Matra2015]. In five of these belts, the CO masses and line opacities have been well established, and the resulting low CO masses and optically thin CO lines can only be explained by a second generation origin [@Dent2014; @Marino2016; @Marino2017a; @Matra2017a; @Matra2017b; @Booth2018]. The origin of gas for the more massive CO-bearing belts remains unconfirmed, but there are indicators suggesting an absence or a significant depletion of H$_2$, which would point toward a secondary origin for them, too [e.g. @Hughes2017; @Higuchi2017]. A puzzling outcome of the first global analysis of the CO detections is a significantly higher occurrence rate of CO in belts around A stars compared to lower luminosity stars [@Moor2017]. Indeed, no detection has been reported to date around stars of type later than F, which constitute the overwhelming majority of stars in our Galaxy. In this work, we aim to understand how the presence of CO gas in a planetesimal belt is affected by its stellar host, and explain the origin of the decreasing CO occurrence rates around stars of decreasing stellar luminosity. We do so by presenting the first ALMA detection of CO in a planetesimal belt around an M3-type [@Ducourant2014] dwarf, TWA 7. This nearby star [34.0 pc, @Gaia2018] is part of the TWA association [@Webb1999], setting its age at $\sim$10 Myr [@Bell2015]. Its infrared excess was detected by Spitzer [@Low2005] and confirmed by Herschel [@RiviereMarichalar2013]. The first, scattered light image of the outer regions of the belt was obtained by HST [@Choquet2016], and more recent SPHERE data resolve the belt’s inner regions showing broad emission from a face-on ring extending from $\sim$20 to at least $\gtrsim70$ au [@Olofsson2018]. Unresolved submillimeter emission was detected by the JCMT [@Matthews2007]. However, ALMA observations recently showed that the JCMT flux is actually dominated by an unrelated source $\sim6.6\arcsec$ offset from the star (likely a submillimeter galaxy), although the fainter-than-expected belt is also detected and marginally resolved [@Bayo2018]. We here analyze the CO cube obtained as part of the same ALMA dataset as described in @Bayo2018. In §\[sect:obs\], we summarize the interferometric observations, including their calibration and imaging. §\[sect:res\] presents our analysis of the CO data and a derivation of physical parameters from measured quantities. In §\[sect:disc\], we demonstrate the exocometary origin of the gas, and examine how of the exocometary release process differs around M stars compared to more luminous stars. Finally, we discuss the origin of the stellar luminosity dependence of the CO detection rates in the context of exocometary gas release. We conclude by summarizing our findings in §\[sect:concl\]. Observations {#sect:obs} ============ TWA 7 was observed by ALMA in Band 7 using the 12m array in 2016. Three observations were obtained, one with 42 antennas in a compact configuration pointed at coordinates RA: 10h42m29.904s Dec: -33d40m17.098s, and two with 36 antennas in a more extended configuration pointed at coordinates RA: 10h42m30.413s Dec: -33d40m16.700s, altogether spanning baselines from 15.1 m to 3.1 km. Further details of the observations can be obtained in @Bayo2018. Standard calibrations were applied to each dataset using the ALMA pipeline in CASA v5.1.0. A CO visibility dataset was produced covering $\sim$1200, 244.141 kHz-wide channels around the transition frequency (345.796 GHz), with continuum emission subtracted from it using the uvcontsub CASA task. For continuum imaging, we considered all 6.9 GHz covered by the 4 spectral windows of each of the observations. For both CO and continuum, calibrated visibilities from the different observations and configurations were imaged both separately and together using the tclean task within CASA, in mosaic mode with multiscale deconvolution. To improve sensitivity to extended emission originating from the belt, we use natural weighting and further apply a 2$\arcsec$ u-v taper to the visibilities prior to imaging. The final CO data cube reaches an RMS sensitivity of 7 mJy/beam in a 244.141 kHz channel (corresponding to 0.21 km/s at 345.796 GHz) for a synthesized beam size of $1.8\arcsec\times 1.7\arcsec$ (62$\times$58 au at the distance of the star from Earth). The continuum image has an RMS noise level of 0.07 mJy/beam for the same synthesized beam size. ![CO J=3-2 spectra of the belt around TWA 7, spatially integrated over the region where continuum is detected at the $\sim$2$\sigma$ level. The top (red) spectrum is obtained without any spectral filtering, whereas the center and bottom spectra are obtained by shifting the 1D spectra at each pixel location by the negative of their expected Keplerian velocity at that location. Two possible signs of the velocity are possible, depending on whether the East side of the belt is moving away or towards us, leading respectively to the green and blue spectra. The grey region indicates the $\pm1\sigma$ confidence interval for the stellar radial velocity [@Gagne2017]. The green shaded region represents the best-fit Gaussian profile to the spectro-spatially filtered emission, used to quantify the integrated line flux.[]{data-label="fig:1dspectra"}](TWA7_CO32_allspectra_vnoselfcal_compandext_smallerpix.pdf) Results and Analysis {#sect:res} ==================== Spectro-spatial filtering: CO J=3-2 detection {#sect:spectrospatial} --------------------------------------------- No strong emission is observed after quick inspection of the CO data cube around the radial velocity of the star [11.9$\pm$0.4 km/s in the heliocentric frame, @Gagne2017]. Following the method of @Matra2015 [@Matra2017b], we apply a spectro-spatial filtering technique in order to boost the S/N and achieve maximum sensitivity (Fig. \[fig:1dspectra\]). First, we simply spatially integrate over the region within $\sim$3.5" from the star where continuum emission from the belt is detected above the 2$\sigma$ level. This produces the red spectrum, where a hint of a Keplerian double-peaked profile already emerges from the noise around the expected stellar velocity. To test whether this signal truly originates from circumstellar gas, we then assume that CO orbits with the Keplerian velocity field expected around a star of 0.55 M$_{\odot}$ [@Neuhauser2000], for a disk with an inclination (13$^{\circ}$) and position angle (PA, 91$^{\circ}$) as derived from high resolution dust imaging in the near-IR [@Olofsson2018]. The unknown rotation direction leads to two possible velocity fields, with the East side of the disk moving away from Earth or towards Earth. For each of the two possible velocity fields, we assign each pixel a given expected radial velocity and shift the 1d spectrum in that pixel along the frequency (velocity) axis, by the negative of its assigned radial velocity. Then, we spatially integrate over the region where continuum emission is detected, to produce the green and blue spectra. We find that the detection is significantly boosted from a peak S/N of 3.7$\sigma$ to 6.4$\sigma$ for a Keplerian velocity field where the East side of the disk is moving away from us, whereas no boost is achieved when the sign of the velocity field is inverted.
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840, 352, 310, 753, 326, 344, 310, 9958, 432, 18134, 414, 2570, 15, 23513, 19066, 14589, 1854, 9909, 16448, 22799, 2746, 281, 253, 6447, 6488, 3678, 387, 6486, 3276, 15, 187 ]	over the years. He is shown defeating the Destroyer. Red and Blue Superman make an appearance in the Superman 75 Year Anniversary short. In the animated series, Justice League Action'', Lex Luthor created a kryptonite-weapon to destroy Superman, but instead it split him into Superman Red and Superman Blue. Each Superman had half of the original's power, but Superman Red was aggressive and evil while Superman Blue was gentle and good. The weapon even did the same thing to Wonder Woman, Batman and Luthor, and the reds plotted to affect the entire world, except for Luthor Red, who was actually good and returned everything to normal. References Category:Comics by Dan Jurgens Category:Comics by Louise Simonson{ "name": "books.toscrape", "request": { "type": "base", "url": "http://books.toscrape.com/" }, "fields": [ { "name": "title", "selector": "h3 a", "extractor": { "types": [ "href", "text" ], "params": { "includeIfEmpty": false } } }, { "name": "image", "selector": ".thumbnail", "extractor": { "types": [ "src", "alt" ], "params": { "includeIfEmpty": false } } }, { "name": "price", "selector": ".price_color", "extractor": { "types": ["text"], "params": { "includeIfEmpty": false } } } ], "paginator": { "selector": ".next a", "attr": "href" }, "format": "json" }Sneak a peek into the music business through brand new eyes. “And I’ll just keep singing because that’s what I do. That’s what I am. I’m a singer. Not a producer, not a writer, not a human. I’m a singer. But, I’ll get to the top if it’s the last thing I do.” – Prologue (Soundtrack 2 My Life) Note:Blueprints of Winnie is unfinished, and will likely remain so. It contains some harsh language. Editorial Reviews Feb 26, 2013: This is a fun little serial about a teen pop singer who knows she can be more. She gets a few breaks, but also falls right into a tabloid sex scandal and maybe gets doublecrossed too . . . but then the story is left hanging (as of Aug 2012). I like the character and the tone. She’s a little cynical, but also puts her heart into life and jumps in with both feet. "I dive head first into the muddy, shallow side of Hollywood. I thought I had to think about it, but in the end it really was a no-brainer." The story had a few enthusiastic followers, so it’s too bad it disappeared without explanation. But what’s there is fun to read, and maybe it will come back . . . . 1 of 1 members found this review helpful. Help us improve! Register or log in to rate this review. Most Helpful Member Reviews No member reviews yet. Your review Register or log in to rate, recommend, review, or bookmark this story.International Auditing and Assurance Standards Board The International Auditing and Assurance Standards Board (IAASB) is an independent standards body which issues standards, like the International Standards on Auditing, quality control guidelines and other services, to support the international auditing of financial statements. It is a body supported by the International Federation of Accountants (IFAC). The Public Interest Oversight Board provides oversight of the IAASB, ensuring that the standards are in the public interest. To further ensure proposed standards are in the public interest the IAASB consults its Consultative Advisory Group, which is composed of standard setters, various international organizations from the private and public sectors, and regulators. Representatives include a balance of users and prepares of financial statements, and should to the extent practicable be balanced geographically. Founded in March 1978 as the International Auditing Practices Committee (IAPC), the IAASB's current strategic themes include: Supporting global financial stability Enhancing the role, relevancy and quality of assurance in an evolving world Facilitating adoption and implementation of the standards it sets See also International Organization of Supreme Audit Institutions International Public Sector Accounting Standards References External links Category:International accounting organizations Category:Auditing standards Category:International standardsAt this point in my life, I go through most days without making a new friend. Sure, an acquaintance or associate here and there, but fewer opportunities to connect with individuals in meaningful, emotional ways. So when I was presented with the chance to build a special friendship with Philadelphia Eagles linebacker Jordan Hicks, I jumped in my car and set forth on a journey neither of us will soon forget. Jordan exemplifies strength, and not just with those muscles of his. He's an inspiration because of how he's been there for everyone in his life, no matter the circumstance. Combine that with his generosity and genuineness and you've got yourself the foundation for a good friend. I guess you could say it was just my lucky day. How could I ever prove myself worthy, though? How do I show him what we have in common and what he would get from our friendship? How do I tell him who "Will" is? It may be tough, but if there's a friend at the end of the tunnel, I'll do whatever it takes. So what do you say, Jordan Hicks: Will you be my friend?characterDef { skin "cvops" mesh "models/players/temperate/axis/cvops/body.mdm" animationgroup "animations/human_base.anim" animationscript "animations/scripts/human_base.script" undressedCorpseModel "models/players/temperate/common/naked.mdm" undressedCorpseSkin "axis_cvops" hudhead "models/players/hud/head.md3" hudheadanims "animations/human/heads/base.anim" hudheadskin "models/players/hud/axis_cvops.skin" } Abstract The paper, starting from the consideration of the main literature on sustainable tourism, is focalized on the analysis of sustainable tourism demand in developed countries. In previous studies, the research group has identified the framework of "4L Tourism", an emerging form of tourism that synthesizes the main tourist motivations in four assets (Landscape, Leisure, Learning, Limit), which require specific tourist offer and products. The paper is based on a field research carried out in Italy on CTS travellers. The research, deliberately aimed to a tourist population with specific behavioural and motivational features, allowed to study in deep the importance of the "4L Tourism" dimensions, highlighting the possibility to graduate the sensibility of tourists in respect with the single dimensions. Coherently with a significant stream of literature on sustainable tourism demand, the analysis enabled to identify two profiles ("4L Tourist hard-path" and " 4L Tourist soft-path") in relation to the intensity of the motivation and to the importance of the single component of the trip. The results of the research permitted, from a managerial point of view, to assess the expectations and the behaviours of "4L Tourists", in order to set up the tourist offer of tourist destinations and organisations, allowing them to follow an emerging global trend in the market with appropriate strategies.Clairvoyants, with the use of their psychic faculties, have observed that every person is surrounded and interpenetrated by a luminous energy body called the bioplasmic body. It is also called as the energy body or Etheric double. This energy body interpenetrates the visible physical body and extends beyond it by four or five inches. It follows the contour of the visible physical body and is called the inner aura. It is unfortunate that many of us lead hurried lives and are too busy to take care of ourselves the way we should — eating well, getting sufficient exercise, and taking the time to get the rest we really need to increase our energy and maintain our mental, emotional, and physical well-being. It’s fortunate, though, that for the stressed person seeking greater vitality, health — and tranquility — amid the hustle of the modern world, there is one particular healing technology that offers a simple, easy-to-implement solution: Pranic Healing®. Signs of Inferiority complex person Inferiority complex symptoms When a person feels that he is less worthy than others, that he is not adequate and that he is worthless then it is said that he is suffering from inferiority complex.Permutation blocking path integral Monte Carlo approach to the uniform electron gas at finite temperature.
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1978, 619, 10541, 4080, 15, 187, 187, 3, 3726, 7320, 617, 275, 281, 789, 275, 253, 31990, 1051, 28489, 767, 2607, 3622, 865, 9545, 466, 753, 15, 2064, 3589 ]	fight to keep myself from swaying as the camp spread open in front of me. It was just that some things had changed in the months I'd been gone. The lower level of the Infirmary had been little more than a hallway of beds and curtains, but all of those were gone now, replaced by stacked, unlabeled boxes. As we moved across the tile, the plastic in my shoe clicking with each stride, I saw PSFs bringing more up from the back rooms and offices. Their curious gazes followed us all the way outside into the pouring rain. Gunmetal-gray skies always drew out the vibrant green of the grass and the trees surrounding the fence. The curtain of water falling around us in sheets didn't dampen the effect in the slightest, nor did it drive away the earthy smell that immediately sent my senses into an overload of visceral memory. I bit my lip and shook my head. It's different now, I reminded myself. You're in control. You are getting out of here. I tried to reach for the old, familiar numb nothing I had lived inside while in this camp, but couldn't find it. The soggy ground shifted under my feet as I found the muddy path. I looked down, and my eyes caught on the sight of the white slip-ons on my feet. The number 3285 stared back, splattered with filthy water and wilted grass. I took a steadying breath and forced myself forward. You're here for a purpose. You are going to get out of here. This was another Op. I could be hard and certain and fight here, too. There was no falling apart now. No giving into fear. Not if I was going to save the others. Rings of cabins curved in front of me, looking darker and smaller than I remembered. I saw holes in the roofs patched over with sheets of warped plastic. The wood paneling along the sides was warping, peeling as the remnants of the last snowstorm dripped down from the roofs. The cold ran like needles over my skin, pinching and stabbing until I finally gave in and started to shiver. The red brick Control Tower at the center of the cabins had darkened under the rain's touch, but there were still multiple PSFs out on the upper ledge, their guns following the paths of each line of drenched kids trudging up the paths from the Garden. Their Blue uniforms clung to their shoulders, the hollows of their stomachs. Most of the kids kept their heads down as they diverted around us, but I caught a few curious glances, all lightning-fast, under the watchful eye of their PSF escort. No—not PSF— I spun on my heel, watching as the soldiers at the end of the line marched on, backs straight, movements choreographed and stiff. They wore crimson vests over their black fatigues. I guided Laybrook off the path with the slightest bit of pressure on his arm, letting the next group pass by us to reach their cabins. Again, walking alongside them at the front and back of the two straight rows were the soldiers in crimson vests. No guns. No weapons of any kind. A warning trill sounded in my mind as the last group came toward us, and terrible suspicion solidified into shock. The red vests were keeping track of the kids, devoid of any emotion. They were young, faces still round and full. My age maybe, or a few years older. They were inserted in the places where the dwindling PSF force should have been. They were Reds. THERE WAS AN HOUR BETWEEN the last work shift, whether it was in the Garden, the Factory, or cleaning in the Mess Hall or Wash Rooms, and when they served dinner. The kids would be returned to their cabins, and each group was allotted a specific time to walk the distance between the buildings. It was a song that only worked if the camp hit each note exactly right. The kids were streams of blue and green, so deeply entrenched in playing their parts that they never stepped out, not even once, to dare interrupt the pace. Reds. God, the others had no idea. I had no way of warning them, and the closer I came to Cabin 27, the more it felt like this was already over. Laybrook followed me up to the cabin, unlocking the door and holding it open for me with a forced politeness. I stepped inside, my eyes meeting his pale ones for the last time. I plugged memories in over the truth, dropped in scenes of him roughing me up, dragging me around, and made him think he was as tough as he wanted to be. The door shut automatically as he turned and walked back into the rain. I knew, by the silence that had greeted me when the door opened, that the girls weren't back yet. They would have switched, just recently, from Factory to Garden duty, and likely were still trudging back through the mud, or waiting at the low fence for permission to move. The cabin—my cabin—was small enough to take in with a single turn. Brown upon brown, broken up only by the yellowing white sheets on the bunk bed. The smell of mildew mixed with a natural body odor, covering even the bland hint of sawdust from the wood. Patches of silver light streamed in through the cracks in the paneling. The wind whispered through the cabin, drawing me around the first few sets of bunks, toward the back wall. I stared at my bunk, a familiar hopeless despair crashing over me. I bit my lip again to keep from crying. Rain had come in through the nearby wall, slanting in to dampen the mattress. I moved toward it like I was underwater, barely feeling it as I sat down. My breath caught in my throat and stayed there as I looked up at the bottom of Sam's mattress. My fingers traced the shapes I had peeled off at night when I couldn't sleep. You left them here. A hand rose up, pressing against my chest, making sure my heart was still beating. You left them here, to live in this hell. "Stop," I whispered. "Stop." There was no way I could ever make up for it. There was no way to go back and change the decision I made that night to swallow Cate's pills. The only way out was forward. I am going to walk out of here. I am going to take every single one of them with me. The door to the cabin popped open. They were silent as they came in, lining the narrow space between the nearby bunks. The PSF came in, counting them off. Then, with a faint smirk, she turned and added me to the tally. The others knew better than to move before the uniform left and locked the door behind her, but nothing could have surprised me more than seeing Sam whirl around, something like hope on her face. Her honey-blond hair had been hastily braided back, and her face was streaked with black dirt. She looked tired, pushed past the point of exhaustion; but her stance, the hands on her hips, the expectant tilt of her head—that was Sam. That was all Sam. "Oh my God." Ellie, one of the older girls. She and Ashley had always tried the hardest to take care of the younger girls. Without her best friend standing shoulder to shoulder with her, I barely recognized her. There was a beat of stillness and then she was rushing toward me, climbing over the bunks that separated us. A good thing, too. I'm not sure I could have moved if I'd wanted to. How was it possible to be bursting with happiness at the sight of them, and still terrified about what they'd think? "Oh my God." Those three words over and over again. Ellie crouched down in front of me, her green shirt splattered with rain. She took my face between her freezing hands, a light touch that turned into a fierce grip once she seemed to accept I was real. "Ruby?" "I'm back," I choked out. The other girls bottlenecked the path between the bunks, and some, Sam included, simply crawled over the mattresses and frames that stood between them and me. Vanessa, Macey, Rachel, all of them, reaching out, touching my face, the hands that were limp in my lap. Not angry. Not accusing. Not afraid. Don't cry, I told myself, smiling even as my eyes burned behind my lashes. "They said that you died," Ellie said, still kneeling in front of me. "That it was IAAN. What happened? They took you away that night, and you never came back—" "I got out," I told them. "One of the nurses planned the whole thing. I met other kids like us and...we hid." The abbreviated truth would have to do—for now. I'd never bothered to ask Cate if the cameras could record sound in addition to video, but the sight of them gathered around me would be dangerous enough. We weren't supposed to touch each other. "But they found you?" This from Vanessa, dark eyes still wide with disbelief. "Do you know if they took Ashley, too? Have you heard anything about her?" "What happened?" I asked, careful to keep my tone measured. "They pulled her in to work in the Kitchen...maybe two months ago?" Ellie said. That wasn
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187 ]	NON-PRECEDENTIAL DECISION - SEE SUPERIOR COURT I.O.P. 65.37 COMMONWEALTH OF PENNSYLVANIA : IN THE SUPERIOR COURT OF : PENNSYLVANIA : v. : : : SEAN ANTHONY MOFFITT : : Appellant : No. 614 WDA 2019 Appeal from the Order Dated March 11, 2019 In the Court of Common Pleas of Allegheny County Criminal Division at No(s): CP-02-CR-0002760-2001, CP-02-CR-0008340-1998, CP-02-CR-0009829-2005 BEFORE: OLSON, J., McCAFFERY, J., and MUSMANNO, J. MEMORANDUM BY OLSON, J.: FILED FEBRUARY 28, 2020 Appellant, Sean Anthony Moffitt, appeals from the March 11, 2019 order entered in the Court of Common Pleas of Allegheny County. We are constrained to quash this appeal. The record reveals the following chronology of events. On March 5, 2016, Appellant filed a writ of errors coram nobis, requesting the court to vacate his October 5, 2006 judgment of sentence.1 Appellant’s Writ of Errors ____________________________________________ 1 Appellant was originally charged with the following crimes: persons not to own or possess a firearm (18 Pa.C.S.A. § 6105); carrying a firearm without a license (18 Pa.C.S.A. § 6106(a)(1)); possession with the intent to deliver a controlled substance (“PWID”) (35 P.S. §780-113(a)(30)); possession of a controlled substance (35 Pa.C.S.A. § 780-113(a)(16)); and, receiving stolen property (18 Pa.C.S.A. § 3925). On October 5, 2006, Appellant entered into a negotiated plea deal in which he pled guilty to (1) persons not to own or possess a firearm, (2) possession of a controlled substance, and (3) receiving J-S08008-20 Coram Nobis, 3/5/16, at 1-27. The court denied Appellant’s writ on April 12, 2016. PCRA Court Order, 4/12/16, at 1. Appellant did not appeal. Thereafter, on June 9, 2016, Appellant filed a second writ of errors coram nobis. Appellant’s Second Writ of Errors Coram Nobis, 6/9/16, at 1-27. Additionally, on April 25, 2017, Appellant moved for the appointment of counsel. Appellant’s Motion for Appointment of Counsel, 4/25/17, at 1. Finally, on June 8, 2017, Appellant filed an amended writ of errors coram nobis. Appellant’s Amended Writ of Errors Coram Nobis, 6/8/17, at 1-4 (un-paginated). In his amended writ, Appellant asked the Post Conviction Relief Act (PCRA) court2 to vacate his judgments of sentence dated January 28, 1999,3 February 25, 2003,4 and October 5, 20065 because his counsel ____________________________________________ stolen property. Appellant was sentenced to 11 1/2 to 23 months incarceration. The other charges were withdrawn. 2 We are referring to the court as a PCRA court because, as discussed, Appellant’s writ of errors coram nobis should have been treated as a PCRA petition. 3On January 28, 1999, Appellant pled guilty and was sentenced to 11-23 months of incarceration for PWID (cocaine) (35 P.S. §780-113(a)(30). 4On February 25, 2003, Appellant entered a plea of nolo contendere and was sentenced to 18-36 months of incarceration for possession of a controlled substance (35 Pa.C.S.A. § 780-113(a)(16)) and PWID (cocaine) (35 P.S. §780-113(a)(30)). 5Appellant’s June 8, 2017 amended writ of errors coram nobis asked the PCRA court to vacate a judgment of sentence for PWID entered on October 5, 2006. Appellant’s Amended Writ of Errors Coram Nobis, 6/8/17, at 1 (un-paginated). As explained in footnote one, however, in October 2006 Appellant entered into a negotiated plea deal and was sentenced for the -2- J-S08008-20 failed to inform him that his convictions could be used in future cases to enhance his criminal record score. Id. As such, Appellant claimed, essentially, that counsel’s ineffectiveness caused him to enter unknowing and unintelligent, and therefore, invalid pleas. Id. On July 24, 2017, the PCRA court denied Appellant’s amended writ together with his motion for appointment of counsel. PCRA Court Order, 7/24/17, at 1. Appellant did not file a notice of appeal. Instead, on August 25, 2017, Appellant filed a motion for reconsideration, requesting that the PCRA court reconsider his “[p]etition for writ of error coram nobis.” Appellant’s Motion for Reconsideration, 8/25/17, at 1. The PCRA court, however, did not respond to Appellant’s motion until March 11, 2019, when it denied reconsideration. PCRA Court Order, 3/11/19, at 1. Appellant then filed a notice of appeal on March 25, 2019, challenging the denial of reconsideration. Preliminarily, we note that Appellant’s writ of error coram nobis should have been treated as a PCRA petition because his claim was “cognizable under the PCRA” and the “PCRA is the only method of obtaining collateral review.” Commonwealth v. Descardes, 136 A.3d 493, 503 (Pa. 2016) (petition for writ of error coram nobis treated as a PCRA petition where claims asserted were cognizable under the PCRA); see also 42 Pa.C.S.A § 9543(a)(2)(ii) ____________________________________________ following charges: persons not to own or possess a firearm, possession of a controlled substance, and receiving stolen property. As part of his negotiated plea deal, the Commonwealth withdrew the PWID charge. Therefore, Appellant’s assertion as phrased in his June 8, 2017 submission is erroneous. -3- J-S08008-20 (recognizing ineffective assistance of counsel as grounds for collateral relief under the PCRA). Accordingly, we “review a denial of PCRA relief to determine whether the PCRA court’s findings are supported by the record and free from legal error.” Commonwealth v. Albrecht, 994 A.2d 1091, 1093 (Pa. 2010). Before reaching the merits of Appellant’s claims, we must address the timeliness of this appeal. The timeliness of an appeal concerns our appellate jurisdiction, which we may raise sua sponte. Commonwealth v. Andre, 17 A.3d 951, 957–958 (Pa. Super. 2011). To lodge a timely appeal from a final order, “the notice . . . shall be filed within 30 days after the entry of the order from which the appeal is taken.” Pa.R.A.P. 903(a). Pursuant to Pa.R.A.P. 1701(b)(3), the time for filing an appeal may be tolled if the court enters an order “expressly grant[ing] reconsideration” within the 30-day period. Id. Simply filing a motion for reconsideration, however, “does not toll the 30-day period for a PCRA dismissal.” Commonwealth v. Collins, 2019 WL 3205786, at *1 (Pa. Super. July 16, 2019) (unpublished memorandum); see also Commonwealth v. Moir, 766 A.2d 1253, 1254 (Pa. Super. 2000). Herein, the PCRA court denied Appellant’s PCRA petition on July 24, 2017, and on August 25, 2017, Appellant filed a motion for reconsideration. The court, however, never expressly granted Appellant’s motion. As such, the 30-day appeal period was not tolled and Appellant needed to file his notice of appeal by August 23, 2017. Appellant filed his notice of appeal on March 25, 2019, 609 days after entry of the July 24, 2017 order and 579 days after the -4- J-S08008-20
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253, 14430, 390, 9569, 247, 22077, 407, 8288, 253, 14430, 33454, 15, 608, 10, 380, 10738, 14278, 273, 2067, 1445, 4896, 1108, 38317, 13, 8115, 13, 25527, 13, 3966, 1108, 18932, 327, 247, 2014, 9400, 27, 4214, 17698, 15, 5220, 9269, 275, 253, 10738, 497, 1781, 19101, 11462, 327, 253, 3402, 15, 2053, 812, 320, 19101, 432, 9647, 457, 1073, 3927, 13, 19101, 432, 30525, 13, 19101, 432, 10846, 665, 17253, 253, 2256, 13, 3966, 15, 309, 5583, 4933, 3484, 247, 773, 47189, 668, 2793, 5001, 247, 1798, 2256, 407, 15250, 731, 342, 247, 5235, 273, 2987, 13, 1690, 19101, 390, 17541, 24392, 13, 326, 512, 4385, 327, 247, 1798, 2362, 15, 21696, 476, 840, 46919, 253, 1491, 281, 1287, 247, 11088, 4685, 273, 253, 2256, 15, 1583, 457, 620, 4366, 6127, 533, 671, 10435, 11297, 534, 588, 7164, 3533, 285, 4446, 616, 4680, 12861, 15, 721, 10, 2091, 2819, 387, 38317, 13, 1908, 604, 597, 457, 250, 773, 87, 525, 23314, 668, 390, 625, 2570, 39062, 15, 2091, 309, 1333, 362, 525, 5464, 13, 309, 1599, 247, 22946, 326, 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2366, 752, 597, 1158, 253, 4067, 2460, 4453, 751, 285, 310, 670, 15, 2635, 13 ]	(-3 - -5). Let x = o + -2. What is the remainder when x is divided by 10? 3 Let b = -41 + 43. Let z be (b + -2)/2 - 13. Let x = z + 18. What is the remainder when 28 is divided by x? 3 Let n = -7405 - -7527. What is the remainder when 14881 is divided by n? 119 Suppose -752v = -718v - 1428. What is the remainder when v is divided by 40? 2 Let d = -361 + 389. Let x(c) = -3c + 3. Let i be x(4). What is the remainder when d is divided by 0 - (1 - (0 - i))? 4 Let g(n) be the first derivative of -n*4/4 - 5n*3/3 - 6n*2 + n - 210. Calculate the remainder when 218 is divided by g(-5). 35 Let w(p) be the first derivative of -8p*2 - 2p + 30. Let x be w(1). Calculate the remainder when 0 - (1341/x + (-2)/4) is divided by 13. 10 Let k(r) = -42r3 - 54r*2 - 5r - 5. Calculate the remainder when 1123 is divided by k(-2). 123 Suppose 0 = -2u - p + 556, 3p - 5p = u - 278. Calculate the remainder when 904 is divided by u. 70 Calculate the remainder when 470236/(-120)15/(-9) is divided by 64. 62 What is the remainder when (-277160)/(-1312) + (-3)/(-4) is divided by 59? 35 Suppose 27q + 247 = 80q - 40q. Calculate the remainder when 1964 is divided by q. 7 Suppose -29g + 250 = 18. Suppose -gx - 21x = -667. Suppose -6k + 4*k = -82. Calculate the remainder when k is divided by xFOR IMMEDIATE RELEASE March 31, 2020 CONTACT: Hannah McKinnon, hannah [at] priceofoil.org Collin Rees, collin [at] priceofoil.org Oil Change International response to Keystone XL subsidy announcement from Alberta Today, the Government of Alberta announced that it would support TC Energy’s Keystone XL oil pipeline with a direct investment of more than USD 1 billion and a further USD 4.2 billion loan guarantee. In response, experts at Oil Change International released the following statements: Hannah McKinnon, Energy Transitions & Futures Director: “Never has there been a more critical moment to support health, workers, and communities. Instead, the Alberta Government is diverting limited and desperately needed public money to Big Oil in the latest misplaced attempt to revive the Keystone XL pipeline and prop up a sector that has no role in a more resilient, safer climate future. “The Keystone XL pipeline was a non-starter a decade ago and it remains one today. With trillions of dollars at play globally in relief and recovery, we have an unprecedented chance to invest in the future, not the past. Unfortunately, the Alberta Government is still refusing to see the writing on the wall, a failure that comes at a huge cost to Albertans in this crisis moment.” Collin Rees, Senior U.S. Campaigner: “This desperate attempt by Alberta’s Government to push through the failing Keystone XL pipeline during a global pandemic is beyond the pale. We need billions of public dollars invested directly in vulnerable communities dying from COVID-19, not spent propping up massive oil companies and unneeded projects that would trample Indigenous rights and exacerbate the climate crisis. “This huge giveaway of public money to fossil fuel executives coming just days after Jason Kenney’s government laid off more than 20,000 educational workers across Alberta says more about where his priorities lie than we ever could. The Indigenous communities, farmers, and ranchers along the Keystone XL route will continue to fiercely resist, and this pipeline will never be built.” ### Notes: This weekend, Premier Jason Kenney’s Alberta Government drastically cut educational funding across the province, laying off more than 20,000 Albertan workers: https://www.cbc.ca/news/canada/edmonton/funding-reduction-alberta-k-12-covid-1.5513803 Oil Change International response to recent Export Development Canada changes: http://priceofoil.org/2020/03/28/oil-change-international-response-to-export-development-canada-changes-in-the-emergency-response-act/ Report detailing more than CAD 10 billion in fossil fuel finance from Export Development Canada: http://priceofoil.org/2018/11/22/risking-it-all-export-development-canada/ Report detailing Canada’s billions in fossil fuel subsidies: http://priceofoil.org/2016/11/16/canadas-fossil-fuel-subsidies/This Wednesday, I attended a workshop at the University of Michigan Museum of Art on a painting by Benjamin West: During the workshop, I noted different strategies employed by the docents and speakers to “teach” us about the art and recorded strategies for using art – as well as general teaching strategies - in the English and/or Social Studies classroom: 1) If you’re using a painting to illustrate a historic event you’re studying or to give historic context to a work of literature you’re teaching, project the image of the artwork and give a mini-lecture on the history behind the work. Also show a map of the relevant region and talk discuss the region’s relationship with the rest of the world and relevant cultural information. 2) Structure lectures in a Q&A format. State the question and then answer it. 3) As an introduction to a historic events, show students a historic painting that illustrates the event and talk about the events that led up to the one depicted in the artwork. Instead of telling students the details of the event, have them make predictions about what’s going to happen based on the artwork and the info you’ve given them on the events leading up to the topic you’re studying. Then, teach the actual details of the event. Afterwards, have students compare what actually happened to their predictions. Also show the artwork again and have students identify what they’ve learned by pointing to particular things in the artwork. 4) To hook students’ interest before studying a particular work, project it alongside a quote that speaks to its legacy or makes a provocative statement about it. You can project the text of the quote or introduce a lecture by speaking the quote aloud. 5) The exhibit consisted of several artworks – portraits, maps, writings, etc – centered on a single topic: General Wolf. Also posted in the exhibit were large quotes printed on the wall. These could be quotes from soldiers’ diaries, quotes from historians, quotes from artists who depicted the subject, etc. I recommend giving students a “gallery” experience regarding a particular subject by presenting them with a variety of works, including quotes or literary passages, that all comment on a particular event. Students can then synthesize the information to develop a comprehensive understanding of the subject. They’ll notice patterns but also contradictions which will raise questions and drive their thinking deeper. 6) When looking at portraits, consider if they’re “vignettes” or more complex narratives. When I say vignette, I mean a portrait that captures a single, focused moment. There’s one thing going on that you’re meant to focus on. Other portraits have various things going on in the image simultaneously. PROJECT IDEA: If you’re having students create a self-portrait or portrait of a character to show their understanding of identity, motives, emotion, thoughts, and goals, consider having them integrate multiple images into a composite portrait. It’ll be interesting to deconstruct and then reconstruct t in a character analysis. 7) When studying the historic facts alongside an artwork that portrays the event, look for accuracies and inaccuracies between the history and the art-story. You could also teach vocabulary alongside this - things like contradiction, paradox, objective vs. subjective, portrayal, etc. 8) Look at multiple works that tell varying narratives about a particular event. You could study tone and consider why the artists portrayed the event differently. You can also talk about artists and artists in terms of reliability. How do we know what’s true? Can fiction make a true statement? How do we piece together contradictory information to draw the most accurate conclusion? 9) Why do authors/artists make changes, additions, and deletions to their characterization of something? 10) The intersection of portrait and idealization. Are realistic works like landscapes and portraits more than representations of something? In what ways are they “re-presentations”, or produced and constructed and skewed, representations of something? Why do this? 11) Historic paintings are often a combination of depicting anatomy, architecture, documenting the landscape, etc. 12) Instead of showing the artwork in its entirety, crop a few images out of it, showing them to students one-at-a-time. Have students analyze each image on its own and have them try to piece together what they think the larger image looks like and is about. Then,
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346, 2598, 13, 359, 564, 323, 10831, 865, 346, 2302, 13, 417, 479, 449, 346, 42, 3255, 346, 42 ]	people, see fit to choose me as their next prime minister," "I will see to it that 1972 will be the beginning of real equality and health and education for all young Australians." "Will you be mounting your production in London?" "I'm not sure." "I haven't thought that..." "My daughter left me before the storm." "Did I tell you that, Lotte?" "She never understood that choosing between the sublime and the sensible often comes at a cost." "Let us not dwell on my children." "I've had enough disenchantment for one day." "Are we wearing our dress?" "We are, Mrs Hunter." "Our baubles?" "But of course." "Then, please, dear Mrs Lippmann, enchant me." "Tonight is unquestionably a night for..." "The tingle tangle." "Faster." "Faster!" "Faster!" "Come over." "Come on." "Oh, no." "Oh, no." "No, b-back." "Back!" "Oh, that's good." "Oh!" "It's coming." "That's good." "That's good." "No, it's not." "Kiss me." "Touch me." "Touch me." "Oh, yeah!" "Ah!" "I'm sorry." "I'm a dead loss." "No." "That's alright." "Here we go." "Ah, ah, ah." "Darling." "What a homecoming." "Darling!" "Darling." "How I've waited." "I thought the lambs were more important than me." "Why have you made me wait?" "Plane delay." "In ghastly Bangkok, of all places." "And then I needed to rest, to be at my best for you, Mother." "You were never, shall I say, deceitful but often devious." "How's poor old Dorothy?" "Dorothy is still poor old Dorothy." "Full of the wrongs done her." "Ah, you're wearing my Ethiopian ring." "The only thing you ever gave me in half a lifetime of absence." "Where's my kiss?" "Look at you." "Oh!" "You'll end up crippled like me." "All ailments are hereditary." "Thank you." "So are moral flaws." "Must I compete already for my son's attentions?" "Go." "You should be staying here, in your old room." "I've booked a room at the Onslow." "I didn't want to put anybody to any trouble." "But I have Mrs Lippmann to care for us." "Poor old Lotte." "The only one in her family to escape the German horrors." "When the Nazis come to town the cabaret dies." "How long since your last employment?" "I have several irons in the fire in the West End, one especially exciting." "Don't expect me to come and see it." "I stopped expecting that long ago, Mother." "Oh, darling." "You know I never come to see you because if you weren't any good, it would break my heart." "But I just might be very good." "They printed the reviews of your "King Lear" in the Sydney papers." "They thought enough of me over there to give me a knighthood." "But that was before your "King Lear"." "Hm." "How's your love life?" "Oh, brilliant, darling." "How's yours?" "He's taller than I thought." "What?" "!" "And sexy too." "He's definitely better in real life." "He is distinguished, certainly." "Yeah." "I could have him." "Save the leftovers for me." "What leftovers?" "Well, I'll be off, then." "Ooh!" "But no." "Mrs Hunter will be upset if I am not feeding you up." "I have to watch my figure." "Well, you've got no worries." "You're in great shape." "Sir." "Please." "Well, just a smidge." "Thank you." "Hm." "Mrs Lippmann is a performer too, you know." "Ah!" "Like yourself." "At a different height, it goes without saying." "You the great artist, me just a dizzy fizzer." "But theatre was necessary for us both, yes?" "Yes." "When we walked out through the lights, we forgot love." "Pain." "Murder..." "For me, performance is probably much like... nursing." "We have to feel the situation, but you can't drown in it." "Oh, no." "So this is for me and whose army?" "I enjoy to feed everybody." "Now, can someone tell me, who's the ancient lilac fairy upstairs masquerading as my mother?" "The creation of another being from one's own body, a complete and decent human being, a fearsome labour for a mother..." "and an actor." "Well, therein lies the play." "I'm not horribly late, am I?" "I expect I am." "Not at all, Princess." "Oh, Dorothy, please." "Oh, thank you." "I must admit, my wife and I privately still call you by that." "How is she?" "I love Lal." "Very well, thank you." "Thank you." "You, um, comfortable at the club?" "Oh, yes, thank you." "I'm there by invitation, you know." "That's very considerate of them." "Well, my brother's late, at least." "Sorry, ladies, I don't have a pen." "No, I have a pen, but..." "I'm sorry, I don't have a proper book." "Would a tissue be alright?" "Fine." "And your name is?" "Lurline." "Lurline." "Lurline." "Skinner." "Is that our country house, Cudgerie?" "Oh!" "There's Daddy." "Yeah." "You and my father were close friends, weren't you?" "We shared an interest in clocks." "I'm afraid nobody, none of us, loved him as he deserved." "Good old Dorothy!" "Oh!" "Oh!" "Basil." "Oh!" "You have improved quite a bit, darling." "Oh." "For God's sake, Dottie." "After all this time, allow me the pleasure of your eyes for a moment or two." "Don't you think we should get on with things?" "Mr Wyburd might have another appointment." "Good old Wyburd." "Mrs Hunter gathered from your letters a certain desire to discuss what might be best for her." "I've, uh, taken the liberty of preparing this." "Hm." "Mmm." "Good." "Mmm." "Yeah, well, you've..." "done a wonderful job." " So..." " Um..." "Well, Basil." "Oh, yes." "Well, um..." "If I may." "What we have to decide is whether a person who's reached my mother's - sorry, our mother's - age derives happiness and comfort from her half-life in proportion to the elaborate and..." "shockingly expensive machinery needed to maintain it." "I mean, surely the needs of old people when their minds are uh, compromised must be... simple." "Mrs Hunter's mind may wander at times, but it always appears to be searching after subtleties." "I'd say she's still the most complex woman I know." "And she enjoys her life." "She's giving away jewellery." "I mean, that Flora girl, how long has she been there?" "Is she the attractive one?" "She's wearing Mother's watch." "Are you aware that she keeps a full-time gardener and a part-time one?" "I believe that Mrs Hunter would rather die than have her way of life dictated to her." "To talk sense into her wouldn't be dictating." "Mmm." "You could do that, couldn't you, dear old Wyburd?" "Your mother asked me to give you these small gifts." "Oh." "Thank you." "Hm." "Let it appear thus." "A minimum of scenery and props." "Nothing to interfere with the inner life of the characters." "It must be architecturally and emotionally sparse." "This could restore one's faith in theatre." "You alright, Mrs H?" "Thanks for the lend of your strong arms, Col." "You're a very strong man for a chemist." "It's a couple of years before I'm a full chemist yet, Mrs Hunter." "Just downstairs on the right, in the living room." "Do you want me to come and pick you up after I close up the shop?" "No." "Well, you'll need someone to get her back up the stairs." "It's alright." "Her son can do that." "Perfect, darling." "Another day, another hairdo." "You look splendid." "Sorry I'm late." "Lilies." "I adore lilies." "Lovely." "Thank you." "Bless you, darling, for your generosity." "You've always had impeccable timing." "Don't spend it all at once." "No." "Yum." "Tea for two?" "Of course." "Gentlemen prefer martinis." "Not with cake." "I'm wearing the white today." "Dorothy!" "Edvard!" "Is she awake or asleep?" "Somewhere in between." "Edvard!" "So, we go for swim?" "No, not me." "I..." "I
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344, 1871, 12759, 253, 13214, 326, 703, 1871, 3078, 281, 320, 347, 1199, 273, 247, 12120, 23660, 347, 617, 3101, 285, 7586, 13, 533, 703, 20296, 253, 7162, 281 ]	be nice?" "Oh, I don't know. I always got the impression that he rubbed you the wrong way." Except for those hot kisses last night, he'd never rubbed her in any way. That was the problem. Funny how it had taken Camille years to figure that out. In the most innocent tone she could manage, she said, "I can't imagine where you got that idea." "Well, you practically laughed with glee when he and Renee divorced." "That's because she was horrible for him," Camille reasoned. "And Matthew should have realized she was a horrible fit for him." "Uh-huh. You mean like you should've seen how Graham was all wrong for you?" Maureen asked smugly. "Exactly," Camille retorted, then sighed as images of last night whirled through her mind. "Actually, Mom, I'm—enjoying Matthew. He's a lot different than the way I remembered." "Different? In what way?" Instead of a spindly young guy, who'd been totally unsure of himself, Matthew had turned into a sexy hunk of confident man, she thought. To her mother, she said, "Well, he was always sort of quiet. That hasn't changed much. But I'm learning he has a bit of a sense of humor and he's a good listener." Pausing, she chuckled. "Or he might just be letting me talk so he won't have to." Several seconds of silence passed and just when Camille was wondering what her mother was thinking, Maureen said, "I'm glad you're enjoying him, honey. I don't have to tell you how much Matthew means to the family. And he's—well, I'm not sure he's ever gotten over his difficult childhood." The things Matthew had told her about his family, or lack of one, were still haunting Camille, and she wondered how he'd grown up to be such a responsible man. If asked, he'd probably give all the credit to Joel, but that wouldn't be entirely right. He'd been a hardworking, trustworthy man when he'd first come to Three Rivers. Joel had simply nourished the goodness in him. Camille said, "Last night he mentioned having a sister. I wasn't aware that he had a sibling. I've never heard any of you mention her. Does he ever see her?" "Not often. The last time was right after you left for Red Bluff. Blake purchased a bull over in California and he sent Matthew to haul him home. The trip gave Matthew a chance to stop by Claire's place." "I see." Deciding she'd better change the subject before her mother started to think her interest in Matthew was a bit excessive, she said, "I guess you're going to have a Halloween party. Do all the kids have their costumes yet?" Maureen chuckled. "Abagail and Andrew are going to be cats with tails and whiskers. That's the most important thing, of course." "How cute," Camille said with a laugh. "What about Nick and Hannah? They probably think they're too old to party with the babies." "Not in the least. Nick and Hannah love being big bosses of their little siblings. And anyway, Viv has promised to take those two to a party on the res that's just for teens and tweens." Missing out on spending time with her nieces and nephews was the one regret Camille often had about making her home here on Red Bluff. On the other hand, it would be difficult living back on Three Rivers and her being the only Hollister sibling without a spouse or a child. It was hard enough to deal with living two hundred fifty miles away. Single and childless at the age of twenty-eight was not the way Camille had envisioned or hoped her life would be. But it had turned out that way and now she was determined not to lament the situation, but embrace her independence. As far as she was concerned that was far better than nursing a broken heart. "Have you seen Emily-Ann lately?" Camille asked. "No. But Katherine sees her regularly. She misses you. I know that much." Emily-Ann had been Camille's best friend since their days in grade school. She ran Conchita's, a tiny coffee shop in Wickenburg that served bakery treats and specialty coffees. "I miss her, too. I'm hoping she can come down for a visit soon." "Emily-Ann isn't exactly flush with money," Maureen pointed out. "I doubt she can afford to stay away from her job for more than a day or two." Camille's friend was dependable and hard working. She'd be great as a waitress for the diner. But in spite of the struggles and stigma she'd suffered through, Emily-Ann would never move away from Wickenburg. It was her home. "I'd make sure she wouldn't have to spend a dime, Mom." "I expected you to say that. So why don't you invite her down for Thanksgiving?" Maureen suggested. "You could take her to Tucson and do some Christmas shopping." "That's a nice idea." "Good. I—" Her mother's words were suddenly interrupted by the sound of distant voices. Camille asked, "Mom, do you need to get off the phone?" "Uh—yes, I'm afraid I do. Blake needs me for something. Love you. And be sure and take extra good care of Matthew." "Yes—I will. And I love you, too." Camille punched the phone to disconnect the call, then rose from the lounge chair. As she walked back to the house, her mother's words played over in her mind. _Take extra good care of Matthew._ What would Maureen think if she knew just how much Camille wanted to care for Matthew? Would she think her daughter was reaching for something she could never have? Last night, when he'd kissed her, she'd thought he was finally going to lower the barriers he'd erected between them. For those few brief moments he'd held nothing back and she'd met the reckless desperation of his lips with the same hungry need. She'd never wanted any man to make love to her as much as she'd wanted Matthew at that moment. But he'd pulled away and implied that their kisses had been a mistake. Could he be right? As Camille went to her bedroom and changed out of her church clothes, the question continued to circle through her thoughts. For the past two years she'd done a lot of growing, and now it was easy to see where and why she'd made the mistake in getting engaged to Graham. Yes, she'd learned her lesson. But what about now? What about Matthew? Oh Lord, never in her wildest dreams had she thought his time here at Red Bluff would mean anything more than having a visitor in the house. She'd honestly expected him to be sullen and curt and she'd planned to ignore him as best she could. How laughable was that? she asked herself as she pulled on jeans and a thin pink shirt. The moment she'd looked across the threshold at Matthew's tired face, something had smacked her right between the breasts. And try as she might, she couldn't get rid of the feeling. But he wasn't down here for romance, she reasoned with herself. Besides, he'd been divorced and single for nearly ten years. The man clearly had no desire to marry again. So what good would it do her to have a brief affair with him? No good. Matthew was right and she knew it. But for some reason her heart wasn't listening to reason. Chapter Five After searching the southernmost range of the ranch for the entire day, Matthew and the small crew of cowhands helping him came up with six of the missing ten steers. Although the men were disappointed that they'd not found the last four, Matthew was pleased with the effort. They could've just as easily ended up with zilch for the day. "When are we going to vaccinate and tag the new cattle, Matthew?" Pate asked, as he steered the double-seated work truck coupled to a long stock trailer over the rough ground. Slumped in the passenger seat, Matthew was attempting to grab a bit of shut-eye during the drive back to the ranch yard, but with Pate hitting every rock in the old roadbed, his head was banging around like a punching bag. Biting back a tired groan, he straightened on the worn leather seat and gazed out the window at the desert hills covered with purple twilight. Red Bluff was an enchanting place and not just because Camille was here, he decided. There were parts of the ranch that were incredibly green to be located in such a desert area. Then there were other parts that were full of high rocky bluffs and hundreds of tall saguaros with their arms reaching toward the wide, endless sky. He wondered how much, if any, of this land Camille ever seen. Did any of it truly matter to her? Or did she only care about the house and having her privacy? Last night, when she'd talked about trying to help out with the ranching chores at Three Rivers, he'd gotten the impression that she'd wanted to be as much of a cowgirl as her mother and sister, but she lacked the confidence to
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24478, 15, 500, 22053, 611, 3178, 280, 369, 247, 10112, 1635, 281, 253, 3961, 13, 273, 48069, 18499, 13, 500 ]	deeply, almost holding his breath as my mother handed this tiny infant into his clumsy hands. Inside were my sister and brother, with my Aunt Cheryl and my mother’s parents. We lived on Northwood for six months before moving to Athens, and as I stroll by I wonder what my life would have been like if we stayed. “No doubt, I wouldn’t be working in a record store, getting drunk off my ass” I think as I quicken my pace. Just past Patterson Avenue, just two blocks from home, I spy Dow’s on High, I need to pee. The campus area reeks of urine from too many drunken frat guys and out-of-campus visitors relieving themselves on the sidewalks, alleys and doorways of High Street and neighboring streets, it is unfathomable that these are the future leaders of the new world. I made a vow not to do this unless it was absolutely necessary, I do a slow motion backwards count of how many drinks I have had, “let’s see, at least four at work but I had pizza and I started at four. Three beers and a shot at Larry’s, that’s only like um, seven and half over five hours. I’m fine.” The alcohol has settled in my knees and around my ears, I can feel it but I am thinking clearly. I don’t want to overshoot it, so, I manage the intake well. this has been done countless times before, I open the door to Dow’s, it isn’t very busy. “I’ll have a Bud, be back in a moment.” The bar is small, with a thin walking space next to the bar and a jukebox that almost hides the men’s room, just to the left of the men’s room is an underutilized room that has a haber-dash of beer signs and posters left over from the nineteen eighties, an old Cleveland Browns poster complete with a schedule from 1990 dangles from the far wall. The season is only half-filled out, by week nine, after a drubbing by the Buffalo Bills that left the morose team, 2-7, even the hardcore owner of Dow’s had given up. And he was an ex-Brown and played for Ohio State. The poster has started to curl at the end, a seldom used pool table sits under a thin hanging light with only three of the four bulbs working, there are stacks of beer protruding from behind an area that was once a kitchen. It would be easy to make off with several cases of beers out the back door which is at the end of a long hallway jutting off from the far wall. That would not happen in a place like Dow’s though, which is the loneliest dive/sports bar on this stretch of High Street. It’s a good place to drink, with polite bartenders who eye us carefully but after several visits accept us. The jukebox sucks, filled with the likes of Journey, Bon-Jovi and Heart, and most times when there isn’t a Brown’s game on it is playing, “Don’t Stop Believing” and “Barracuda” for the four thousandth time. I wait outside the men’s room, although there are only a handful of patrons in the bar, one of them is taking a leak. Behind me sits a small table, with a crock-pot filled with homemade Barb-queue, and a large spoon ready to fill up a thin white roll that is housed in a yellow and clear plastic bag. A stack of styrophom plates and a bag of rippled chips sits on the table. There is a football game flickering on the television but it is not the beloved Browns. While waiting to pee, I shake my head at the juke book, where Billy Idol is bellowing away. Dick’s Den is one of the oldest bars around the campus area, with multiple nights of live jazz being played, although Dick’s was no piano bar, a tiny almost platform stage wedged between a the doorway to the most cramped area laid out for a pool table, just to the left of the doorway, shoved into a corner as if straddling a cliff sat a Terminator II pinball machine. If you played the game a bit rough, full with fits, bumps and lunges you may well make the jukebox, filled with Billie Holiday, Duke Ellington and Miles Davis, skip. Below the stage were a handful of tables, where the drinks would jockey for space much like the musicians on the stage. The bar staff was older than the staff at Larry’s, the Blue Danube and Staches, with many left over from the High Street debauchery of the 1960’s and 70’s. It was, in a way the post-doc equivalent of a bar compared to the graduate student manner of Larry’s. I was usually frustrated with doorman at Dick’s, due to the explosion of college clientele during their carnival/riotous nights of quarter beer nights during the early nineties. While, I’m sure the loved the business they made quick changes to the flood of frat types on the Wednesday nights of quarter beer nights, the first upping it to .50 beer nights and cracking down on carding people. I took some umbrage at being carded every time I went into Dick’s, mostly because I drank there at least once a week and also for the fact that I had assumed I had long-ago cemented my credentials as a High Street veteran. Dick’s was busy that night because, sure enough, it was .50 beer night and as I stuck my ID back into my back pocket, I eyed Jenny sitting at the bar with a tall bottle of Rolling Rock in front of her. “Hey,” I said as I saddled up next to her, raising my finger to the bartender and mouthing the words, Budweiser to him. He was a Used Kids regular, prone to buying Lucinda Williams, Jimmie Dale Gilmore as well as jazz titles, he nodded and smiled, silently placing a beer in front of me he stuck his hand up, signaling I didn’t need to pay. I flipped him $2 for a tip and nodded my thanks. Jenny smirked at me, “you come here often I guess?” Looking sideways at her, as I lifted the bottle, now neck empty, “not too much, really, maybe once a week. He comes to the shop a lot, I usually give him a deal. The secret to successful drinking is to know how to treat your bartender, in or out of the bar. Smiling, and shaking her head, “I see that.” After a few formalities she cut to the chase, “hey, I think it’s cool that you asked me to join you, I could have paid for a ticket but you know, graduate school money doesn’t go very far. So, that was nice. But I need to let you know I have a boyfriend, Kevin, and he lives in Philadelphia. I just don’t want you to think that, um, I don’t know…..”, she looked skywards, “now, I feel stupid.” Thinking to myself, “only Jerry thought this was a date”, I smiled, “I didn’t think of anything more than just getting you in, really, I didn’t think this was a date or anything. I’m not good at that sort of thing anyway.” In some way I was relieved, shirking from any sort of romantic investment was easy for me, a great deal of the people I spent time with were woman, almost all on a platonic level. “Whew, I was worried you might be upset with me,” she replied, almost to herself, and it was obvious a burden was taken off her shoulders. “nope, not at all.” I stuck my hand up for two more beers, pointing to her half empty bottle and my empty one. “Don’t you think we should go? It’s like 10:30 and I think the ticket said 9:30. I wanna see your friend’s band, Gaunt.” “it’s alright, shows here start late, and besides there is another band playing first, there are always three bands. I think their called Swivel-Arm Battlegrip, Gaunt will go on in about twenty minutes and they’ll play a short set because Jerry is nervous about playing with Unrest. He loves them so he won’t play too long.” Staches was half-full, Unrest had just put out the finest record of their career, “Imperial F.f.r.r.” and chimy, ringing piece of guitar pop, the was one of the most catchy records of the year. They had played Staches the year before, again with Gaunt, and were lack-luster as was the turnout for the show. It was a decent crowd for a Wednesday night, and when we entered, I got three beers from the bar, two Budweiser’s for me and a Rolling Rock for Jenny. “you don’t have to buy me any drinks, in fact I probably shouldn’t drink very much more, I have class tomorrow.” “It’s ok, I don’t mind.” I motioned to the stage, where Jerry was just getting ready to plug his guitar in, Gaunt had jelled into quite a live band by this point, having released three records on Thrill Jockey (“Whitey the Man”, “I Can See Your Mom From Here” and “Sob Story”) and doing several tours. Jovan Karcic was a welcome addition to the band, of Serbian descent, J
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0.925& 67&126&$-$3.6& 3.2& 0.1&$-$14& 23&18.1& 0.3& 17.9& 0.3& 10.75& 0.03& 529& 299& 518&293& 224& 113\ & 1.408& 7&278&$-$2.8& 0.1& 3.4&$-$21& 1&18.0& 0.3& 17.9& 0.2& 10.14& 0.02& 525& 297& 519&293& 206& 102\ & 1.642& 71&189&$-$3.0& 3.0& 0.6&$-$18& 27&17.5& 0.4& 17.4& 0.4& 9.72& 0.03& 501& 282& 494&278& 194& 95\ \ B1737+13& 0.408& 84&109&$-$4.2& 0.8& 1.3&$-$14& 4&22.1& 0.6& 18.2& 0.8&& 359& 175& 252&122&\ & 0.610& 54& 20&$-$2.7& 0.7& 5.2&$-$17& 6&28.4& 1.5& 23.2& 0.4&& 581& 293& 397&193&\ & 0.910& 85& 58&$-$2.4& 0.2& 0.8&$-$24& 3&20.8& 0.3& 20.1& 0.3& 16.70&0.08& 322& 155& 302&145&216 &101\ & 1.408& 38& 23&$-$1.6& 0.8& 2.4&$-$22& 16&24.6& 0.6& 23.4& 0.3& 15.88&0.08& 443& 217& 401&195&198 &84\ & 1.642& 32& 58&$-$1.5& 2.3& 1.9&$-$21& 47&22.3& 0.3& 21.5& 0.3& 15.24&0.04& 367& 177& 345&166&184 &92\ \ B2045$-$16&0.408&111& 8&$-$1.5& 0.1& 0.5&$-$36& 3&19.4& 0.4& 19.2& 0.3& 12.88& 0.01& 810& 245& 792&239& 366& 110\ & 0.606&129& 2&$-$1.4& 0.1&31.1&$-$32& 1&22.7& 0.3& 22.3& 0.4& 12.09& 0.01& 1107& 334& 1066&322& 325& 97\ & 0.925&136& 53&$-$1.1& 1.1& 0.5&$-$36& 50&17.8& 0.4& 17.5& 0.4& 11.28& 0.02& 688& 209& 661& 200& 285& 86\ & 1.408&121& 6&$-$1.4& 0.1&10.2&$-$35& 3&19.6& 0.2& 19.3& 0.2& 10.84& 0.01& 829& 250& 805&242& 264& 80\ & 1.642& 99& 9&$-$1.7& 0.1& 4.3&$-$34& 2&18.8& 0.3& 18.5& 0.3& 10.71& 0.01& 763& 230& 737&222& 258& 78\ & 4.850& 92& 77&$-$2.4& 0.3& 2.5&$-$24& 4&14.7& 0.1& 14.3& 0.1& 10.11& 0.01& 471& 141& 445&134& 232& 70\ \ B2111+46& 0.610& 12& 10&$-$1.1& 1.0&15.8&$-$10& 13&88.7& 1.3& 86.2& 1.3& 59.07& 0.02& 683& 483& 647&456& 318& 215\ & 0.925& 13& 25&$-$1.4& 2.8& 3.1& $-$9& 25&82.1& 1.2& 79.1& 1.1& 55.29& 0.04& 591& 414& 551&384& 281& 189\ & 1.408& 13& 4&$-$1.4& 0.5&61.2& $-$9& 4&86.9& 1.9& 82.8& 1.8& 51.12& 0.02& 658& 464& 601&422& 243& 162\ & 1.642& 14& 28&$-$1.5& 3.0& 1.8& $-$9& 26&75.7& 0.5& 74.5& 0.4& 49.13& 0.06& 507& 352& 492&341& 225& 149\ & 4.850& 16& 42&$-$2.5& 6.6& 1.1& $-$6& 22&75.1& 0.6& 73.2& 0.6& 46.07& 0.03& 499& 346& 476&330& 200& 132\ [c@ l@r@[$\pm$]{} l@r@[$\pm$]{} l@r@[$\pm$]{} l@r@[$\pm$]{} l@ c@ c@ l@l]{} PSR B& Freq& & & & & ${\rm r_{\rm geo}^{\rm KG}}$& $\frac{(\rm r_{\rm geo}^{\rm OTS})}{(\rm r_{\rm delay}^{\rm BCW} (OTS))}$& $s$\ & (GHz)& & & & & (km)& & &\ B0301+19 & 0.408 & -0.48 & 0.54 & -1.18 & 0.24 & 139 & 157 & 341 & 70 & 567 & 0.87 & 0.66\ & 0.610 & 0.01 & 0.68 & -1.09 & 0.05 & -4 & 198 & 315 & 15 & 511 & -42.71 & $--$\ & 0.925 & 0.16 & 0.35 & -0.28 & 0.13 & -47 & 101 & 81 & 40 & 458 & -2.64 & $--$\ & 1.408 & -0.25 & 0.32 & -0.22 & 0.08 & 72 & 92 & 64 & 24 & 411 & 1.71 & 0.92\ & 1.642 & -0.50 & 0.88 & -0.68 & 0.66 & 146 & 254 & 197 & 192 & 395 & 0.55 & 0.52\ \ B0525+21 & 0.408 & 0.14 & 0.29 & 0.28 & 0.12 & -115 & 232 &-219 & 100 & 971 & -16.78 & $--$\ & 0.610 & -0.30 & 0.49 & -0.48 & 0.05 & 238 & 386 & 378 & 40 & 875 & 9.51 & 2.18\ & 0.925 & -0.21 & 0.36 & -0.28 & 0.08 & 165 & 286 & 224 & 68 & 785 & 11.52 & 2.40\ & 1.408 & 0.09 & 0.29 & 0.18 & 0.05 & -73 & 228 &-140 & 45 & 704 & -27.89 & $--$\ & 1.642 & 0.29 & 0.49 & -0.11 & 0.13 & -232 & 389 & 87 & 106 & 676 & -8.41 & $--$\ & 4.850 & -
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3289, 14, 13060, 9509, 13, 247, 5754, 323, 37187, 30380, 285, 20086, 13, 285, 247, 5718, 1659, 15, 7667, 682, 369, 4272, 715, 1264, 44869, 9070, 407, 6703, 8099, 326, 1335, 6225, 275, 253, 49747, 5331, 15, 7850, 6150, 8099, 285, 6703, 8099, 574, 19525, 8346, 18488, 285, 2800, 6703, 18488, 5909, 715, 1027, 25237, 15, 187, 187, 19393, 682, 3304, 253, 8099, 369, 247, 42350, 26956, 749, 26613, 342, 1052, 13, 933, 1327, 14, 38682, 285, 6705 ]	osphorus. The Greek communities lived along the seacoast in Kum Kapı, Samatya, and Fener. The headquarters of the Greek Orthodox patriarchate had been located in Fener since 1601. Members of the Greek Phanariot community carried out trade on the Black Sea, supplied dragomans (translators) to the Porte, and were appointed as princes of Moldavia and Wallachia. The Jewish community lived mainly in Balat and Ayvan Sarayı along the left bank of the Golden Horn in the eighteenth century (see chapter 2). The Armenians and the gypsies lived by the western wall in Sulu Kule and Samatya. The headquarters of the Armenian patriarchate was in Samatya. The Greek Orthodox and Armenian patriarchs were appointed by the sultan with extensive rights to administer the religious, legal, and cultural affairs of the Greek Orthodox and Armenian communities throughout the empire. The district of Istanbul contained the Topkapı Palace, the Hippodrome, the Friday mosque of Aya Sophia, and the Grand Bazaar. The Topkapı Palace complex, the private residence of the Ottoman dynasty and the center of government, stands on the first hill at the eastern tip (Saray Burnu) of the peninsula. Mehmed II built the palace over parts of the Great Byzantine Palace and the Acropolis in 1479. Enclosed by walls and divided into four courts, the Topkapı Palace contained public buildings where government business was conducted. The Topkapı Palace housed more than 6,000 people, of whom 500 were women, in the late eighteenth century, according to some accounts. The first court of the Topkapı Palace, also called the janissaries' court, contained military installations, the armory, the mint, and the Executioner's Fountain, where the executioner washed his hands after beheading high officials. The second court contained the Imperial Council, which functioned as a cabinet and a higher court of appeals (see chapter 8); the Inner Treasury; the Public Records Office; the grand vizier's office; and the palace kitchens (ten spacious rooms) that served food for several thousand people daily in addition to the poor. The executioner's room with a small prison was at the gate of the second court. The third court contained the Throne Room, where the sultan received officials, petitioners, and foreign ambassadors; the Pavilion of Holy Mantle, where the relics of Prophet Muhammad were preserved; the Privy Chamber; the Campaign Chamber; the Treasury Chamber; the palace school, the mosque of the janissary agha (head of the janissaries), and the library of Ahmed III. The imperial harem, the tulip garden of Ahmed III, and kiosks were located in the fourth court, the center of the private life of the sultan and his family, which overlooked the Sea of Marmara. The imperial harem was a vast building that occupied parts of the second and third courts and had more than three hundred rooms that housed several hundred female members of the dynasty, Ottoman princes, and their large staff headed by the chief black eunuch. The Topkapı Palace was used as the royal winter residence in the eighteenth century. Sultan Ahmed III commissioned a public fountain across the outer (Bab-i 'Ali) gate of the Topkapı Palace, added a library to the palace, and restored several buildings such as the Imperial Hall, the dining rooms (the fruit room), and the petition chamber. Persian decorative floral patterns and the French rococo style marked the new additions to the palace made by Ahmed III, Abdulhamid I, and Selim III in the eighteenth century. Adjacent to the Topkapı Palace was the Friday mosque of Aya Sophia and the former Byzantine Hippodrome. The Hippodrome was the ancient ceremonial center and the public square. Built by Emperor Setemius Severus in 1203, it was later extended and remodeled by Emperor Constantine the Great. It contained obelisks and columns, three of which still stand today; the Ibrahim Pasha Palace (grand vizier of Sultan Süleyman); and the mosque of Sultan Ahmed I (the Blue Mosque). Due to its function as a ceremonial center and location, many riots began in the Hippodrome in ancient (532 A.D.) and Ottoman times (see chapter 3). Under the Ottomans, it was renamed At Meydanı and continued to function as the ceremonial center. Processions, military drills, and public festivals celebrating the birth and circumcision of Ottoman princes and the birth and wedding of princesses took place in the Hippodrome. The janissary barracks (old and new rooms) and the Et Meydanı (meat square), where janissaries received their meat ration, were located on Divan Yolu and near the Hippodrome. The rebels used the Hippodrome as their base in 1703 and 1730 (see chapter 3). The commercial hub of the city was located very close to the Hippodrome and the Topkapı Palace. The Divan Yolu ( _via ignatia_ ) branched out in several directions from the Hippodrome and connected the area to the mercantile center of the city, the Grand Bazaar and its surrounding residential and commercial districts on the one side as well as the Egyptian Market and the port (Eminönü area) on the other side on the Golden Horn. Most of the 3,667 shops, numerous _hans_ (guest houses) and caravanserais, mosques, _medreses_ (Islamic seminaries), hospitals, and hospices were part of the Fatih, Bayezit, Süleymaniye, and Turhan sultan imperial pious and charitable ( _vakf_ ) foundations that were built during the sixteenth and seventeenth centuries in this district. In addition, the shipment, provisioning, and distribution of foodstuff and raw materials took place in the port area on the Golden Horn, where ships from all over the empire and the Mediterranean ports anchored. The Un Kapanı (flour depot) and Yemiş iskelesı (fruit scale) distributed flour to bakers at government-set prices and fruits citywide. In the marketplace various religious communities mingled together, carried out business, and belonged to the same guilds. As would be expected, this area also became a center of crime due to its commercial wealth and social diversity. The district of Istanbul was under stricter government control than the rest of city because the Topkapı Palace, the main residence of the sultan and his family, was located here. The administration of the city was under numerous officials: the grand vizier and his retinue of janissaries, the chief kadi (Islamic judge) of Istanbul, the chief inspector of markets, the chief of night police, the chief of day police, the _agha_ (commander) of janissaries in Istanbul, and the head of the palace guards (see chapter 7). #### THE EUROPEAN HUB: _GALATA_ Galata and Pera, on the opposite side of the Golden Horn from the district of Istanbul, were the hub of Western European trade and the center of diplomacy, finance, entertainment, and European residence in the early modern period. The walled town of Galata was a former Genoese colony, part of the Italian trading settlement on the Black Sea during Byzantine times. Galata had gained full autonomy because of its alliance with the Byzantine Empire against Venice during the restoration of Byzantine rule in 1261. It also had lent financial and military support to Byzantine forces during the Ottoman siege of March–April 1453. Some merchants had collaborated with the Ottoman army and handed the keys of the city to Mehmed II two days after the fall of Constantinople. Because of its timely surrender, Galata survived as a distinct city within a city under the Ottomans. The Ottoman sultan had rewarded the colony by granting capitulations to Genoa and partial autonomy to the town. The treaty provided the Genoese colony with religious and commercial freedom, security, and protection of property as well as exemption from extraordinary taxes, forced labor, and residents' service in the army. The colony also received the right to elect freely a person to represent its interests before the sultan. In return, the residents had to agree not to build new churches or ring their bells too loudly. These privileges were later granted to other Italian city-states and western European nations in the seventeenth and eighteenth centuries. Mehmed II divided the community in Galata into two groups, the non-Muslim Ottoman subjects who paid the poll tax and the subjects of Genoa who resided temporarily in Galata for commerce. The first group of non-Muslim subjects ( _zimmis_ ) included Greeks, Jews, Armenians, and some Genoese. The second group, defined as protected non-Ottoman merchants, received the freedom to trade in return for payment of customs dues. Both groups enjoyed distinct legal and religious autonomy. To establish Ottoman control over Galata, Mehmed II razed some of the land walls and kept the sea wall intact. However, the walls were restored by his son Sultan Bayezid II (1481–1512). The Galata tower (100 feet high and 50 feet in diameter) functioned as a fire-watch facility, a prison for indebted merchants and slaves, and a storage place. Galata was divided into three wards separated by inner walls that still stood in the seventeenth century. Its sea walls and inner walls had eleven outer gates and six inner gates opening into different neighborhoods. Galata inside the walls was a densely populated subdistrict with 200,000 non-Muslim and 64
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1008, 67, 3583, 2498, 380, 21891, 6735, 310, 253, 673, 14, 7555, 19416, 2957, 273, 3417, 347, 247, 906, 273, 20571, 12536, 285, 27159, 534, 778, 2826, 14649, 1996, 275, 253, 3807, 382, 16193, 14251, 326, 6376, 846, 12536, 15, 329, 30868, 275, 253, 1180, 273, 3417, 310, 2540, 13, 1309, 247, 19040, 673, 313, 2068, 9977, 16653, 582, 846, 247, 17190, 2362 ]	]; Liu et al., [@b66]), especially due to the destruction of habitats. Habitat heterogeneity and the intense productivity of such habitats, due to the higher availability of nutrients, could be possible explanations for peaks of species richness in suburban areas (McKinney, [@b71]). This also raises the issues of SAR dependence on scale, with consequences for LCA as characterization factors cannot be easily aggregated or disaggregated and applied to different scales. Other negative biodiversity impacts may also be observed, depending on the location of a disturbance or a forcing event. Bell ([@b10]), suggested that tropical rain forest birds tend to have more difficulty adapting to urban areas than do birds from other natural areas, such as temperate forests. de Baan et al. ([@b7]) devised an LCIA method using regionalized predictions of species recovery times from Curran et al. ([@b23]). This method broadly considers differentiated species responses. However, it should be noted that birds are a peculiar taxon due to their particularly large range of activity, and so it is unclear if the small marginal changes studied in LCA have a significant individual effect on bird species. The issue of how to reconcile scale in a method that addresses the marginal impacts of single-product production is thus far unresolved. Surrogate species: is there a unique choice for global assessments? ------------------------------------------------------------------- This discussion brings us to the species chosen as proxy or surrogate for the impact assessments, i.e. individual species used to represent the species richness of an area, or to predict the behavior of the entire environment when facing specific pressures. Such surrogate species are especially needed when detailed data, such as species distribution, are not sufficiently available (Lambeck, [@b64]; Hortal et al., [@b48]; Murphy et al., [@b77]). In conservation biology and environmental planning, biodiversity measures are essential to predict the status and changes of ecosystems. One of the biodiversity measurement options available is to use beta (β) diversity of surrogate species (Mazaris et al., [@b70]). According to Whittaker ([@b107]), alpha diversity is the species diversity of a community or habitat, beta diversity is the diversity between (neighboring) communities, and gamma diversity is the one diversity of a region (at a larger scale). Surrogacy can be of three types: cross-taxon, for which the species richness of one taxon is used to infer conclusions in other taxa; within-taxon, where a higher hierarchy ranking, i.e. genera, is used as surrogate; and environmental, for which parameters such as temperature are applied (Magurran, [@b68]). In LCIA, cross-taxon surrogacy is commonly used. Surrogacy is also used to indicate the anthropogenic influence on biodiversity, focusing on conservation, monitoring, and management actions, and in a political context, to direct attention to specific environmental aspects (Caro & O\'Doherty, [@b15]). Surrogate species are generally used due to the impossibility of measuring the overall biodiversity in a certain area, given the difficulty of collecting sufficient relevant data (Groves et al., [@b44]; Margules et al., [@b69]). Despite the apparent usefulness of surrogate species in impact assessment, no consensus exists on the use and consequences of the specific species chosen (Favreau et al., [@b38]). Some authors contend that the use of a surrogate, without verifying effective environmental responses, might compromise the effectiveness of the conservation aims (Andelman & Fagan, [@b2]; Cushman et al., [@b24]; Santi et al., [@b89]; Murphy et al., [@b77]), mainly because the cross-taxon surrogacy (i.e. of different taxa and species) may be poor (Kremen, [@b61]; Negi & Gadgil, [@b78]; Santi et al., [@b89]). Favreau et al. ([@b38]) argue that the use of surrogate species should be based on good knowledge of the affected species and how they interact with their environment. They might be a single or a group of species, chosen for various criteria such as body size, which is correlated with sensitivity to disturbances and lifetime (Caro & O\'Doherty, [@b15]). Most ecological processes are dependent on the scale and time (Wiens et al., [@b108]), and these two factors will also influence the ability of one species to reflect the behavior of others (Cushman et al., [@b24]). A meta-analysis of 138 different studies has shown that the use of different taxonomic groups for the assessment of land-use impacts might lead to different results, due to differences in sensitivity to land-use change (Gibson et al., [@b43]). It was found that mammals were less sensitive to disturbances in the landscape, while birds were shown to be particularly sensitive, especially to the land-use change from forest into agriculture. Within some groups, different taxonomic orders were found to be impacted differently. Santi et al. ([@b89]) investigated the degree of concordance among species richness and compositional patterns of different taxonomic groups, and found little cross-taxon congruence among most taxa. The choice of surrogate species is still debated and is barely discussed in current applications of land-use impact assessment in LCA, although it is recognized that different taxonomic groups should be used (de Baan et al., [@b6]; Souza et al., [@b95]). Vascular plants have been used in the assessment of the magnitude of land-use impacts (Müller-Wenk, [@b76]; Koellner, [@b54]; Weidema & Lindeijer, [@b106]; Vogtlaender et al., [@b104]; Michelsen, [@b73]; Schmidt, [@b92]), without further verification of the cross-taxon congruence/surrogacy of species diversity. Vascular plants have historically been used in land-use impact assessment in LCA mainly due to data availability (Schmidt, [@b92]) and the belief that they might correlate well with other species (Koellner, [@b54]; Weidema & Lindeijer, [@b106]; Vogtlaender et al., [@b104]), even though some authors argue that vascular plant species are an inappropriate surrogate indicator for biodiversity (Michelsen, [@b73]; Schmidt, [@b92]). Besides these issues, current discussions barely touch the importance of the choice of surrogate species. One complicating factor is that LCA requires models that can better represent a more globalized characterization of impacts, due to the global or cross-regional coverage of different production systems. Biodiversity dynamics: does it matter? -------------------------------------- In this section, we discuss the influence of ecological phenomena such as extinction debt and immigration credit on the assumptions of the impact assessment framework. We assess how compromising the disregard of related phenomena such as landscape interactions and species assemblage is to land-use impact assessment in LCA. The treatment of land interventions as being static, as in the current framework, is inadequate for reflecting changes in species diversity. In reality, these changes are not simply a result of the postponement of the recovery of land (occupation, LU), or a unique change in unit time (transformation, LUC), but the consequence of continuous anthropogenic activities and other environmental conditions, such as climate change. The land impacts that are considered do not reflect the cumulative effect of practices actually taking place. A fundamental issue with this model is that, for some land-use changes, extreme drops in the quality after land transformation are unrealistic if the metrics implemented refer to biodiversity (Kuussaari et al., [@b63]). With regard to species richness, and to use an extreme example, the conversion of land from natural vegetation to intensive agriculture will not instantaneously extinguish all local species and reduce the level of biodiversity as soon as the new land use takes effect. This concept of a delayed drop in quality (expressed in species diversity), and related temporary diversity surplus, is relevant to the issue because if losses are progressive and occupation is short enough, land-use impacts may be lower than expected. Conversely, if a patch of land is occupied over a relatively long period of time, the total impacts over time may lead to a threshold limit of biodiversity quality (Gibson et al., [@b43]) being met, leading to the collapse of the ecosystem. In this case, the difference between the initial and final steady-states should be higher. Documented examples show that extinction debts may persist for more than a century (Vellend et al., [@b103]; Cousins & Vanhoenacker, [@b20]), and this may lead to an underestimation of the potential impacts of land-use change on biodiversity. The ecological concepts of 'extinction debt' (Tilman et al., [@b96]) and 'immigration credit' (Jackson & Sax, [@b52]) were established to address the reasons why it is empirically observed that species levels decay at a slower rate than predicted by models. An immigration credit is the number of new species that immigrate to a certain area, following a disturbance, during a time elapsed (immigration lag) between the disturbing event and the establishment of the species (Jackson & Sax, [@b52]). The extinction debt is the time-delayed loss of species as a result of habitat destruction and fragmentation which may occur generations later in the undisturbed fragments that remained after destruction. A surplus in the number of species is observed, during a definite time (extinction lag), after a forcing event
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23903, 591, 46740, 15, 11706, 13, 2263, 4599, 2458, 2075, 2190, 253, 4585, 3678, 10474, 275, 253, 5674, 13, 387, 670, 9934, 23903, 591, 46740, 949, 4400, 13, 1375, 285 ]	That’s debatable, but DC embraced it when the Batman titles underwent a soft relaunch after the year-long No Man’s Land crossover, with a redesign from Dave Johnson. It wasn’t just the costume, either. Johhnson also redesigned the GCPD uniforms with a really good retro style and even offered up a new design for the batarang, clearly going for a stripped-down approach that evoked The Animated Series. It’s a good-looking suit, and since printing had come quite a long way since 1964, the logo never blended into the costume the way it did back then. Plus, the treads on the boots are actually a good use of a seemingly inconsequential detail, in that they’re a subtle reminder of Batman’s lack of super-powers. The cape and cowl tell you he’s a superhero, but he’s also a guy who needs shoes with a little grip to them when he’s climbing up walls and chasing down crooks. 4: The Bat-chelor Party Batman costume (2018-Present) As you might’ve heard, Batman was supposed to get married in 2018, and then he didn’t. Then he got sad and decided that he was so sad that he could no longer wear purple and yellow, the colors of happiness. And so, Batman did what so many of us do when we’re depressed: He went back to whatever he was doing twenty years ago. In his case, that was a return of David Mazzucchelli’s Year One costume. It’s functionally the same as the “New Gotham” suit — including the boot treads — but the cape, cowl, trunks, and boots are all black instead of dark blue, which is weird. You’d think a guy that sad would be… feeling blue. It’s fine, but it definitely feels like a skittish step backwards after the Rebirth suit that it replaced. 3: The Zero Year Batman costume (2013-2014) When Scott Snyder and Greg Capullo got the job of giving Batman an updated origin story, they decided to pre-emptively counter the comparisons to Year One by just going in the opposite direction. Year One is a gritty, violent story set against the backdrop of the ‘80s crime wave. Zero Year is a neon-pink nightmare where Batman has to wrestle a lion because of the Riddler. It also features the return of the purple gloves which, like the lion-wrestling, is a bit of the Golden Age updated with a modern take. This suit is a weird one, but it’s a good take on mashing up the over-detailing of the New 52 with signature elements of Batmans’ past. Plus, the story also features Batman wearing a short-sleeved shirt and wrestler boots while doing dirtbike stunts, which doesn’t stick around long enough to be an official costume, but would make a solid runner-up for Best Batman. 2: The Rebirth Batman costume (2016 - 2018) After years of tooth-gritting seriousness, it was inevitable that the pendulum would swing back to embracing the bizarre, and the past ten years have been the weirdest Batman has seen since the ‘50s. Remember when Batman was Jim Gordon in a giant blue robot for a minute? Or when he died and came back to life because of magic metal and then got his memories back from a clone machine he keeps in his basement? Or when he had to fight his interdimensional murder-dad? That was last year. Greg Capullo’s Rebirth-era design reflects that. It has the heavy gauntlets and boots of the hilariously self-serious Arkham games, but they’re thrown in there with a bunch of delightfully weird touches. The utility belt is designed to look like fangs, the interior of the cape is a purple gradient for dramatic (and colorful) backdrops, and while it lacks the oval, the bat-symbol has a bright yellow outline to make it pop. It’s great. Batman is a person who does karate at homicidal clowns on a regular basis. He should look a little weird. 1: The “New Look” Batman costume (1964 - 1993) After it was refined a few times in the early years, Batman’s costume, much like Superman’s, would remain largely unchanged for the next 50 years. The keyword there, though, is “largely.” In 1964, Detective Comics #237 announced the “New Look” Batman, which basically amounted to exactly one change: Batman’s logo got a yellow oval around it. According to Michael Uslan, the producer of every modern Batman film, this was done to make the logo easier to trademark in advance of the Batman TV show, but there’s also a very practical artistic concern. Unlike Superman’s striking, immediately recognizable S — and the big blue 4s and spiders over at the newly minted competition — the black-on-grey logo was pretty easy to miss in the art. The oval made it pop, and tied it to the striking visual of the Bat-Signal, which had been around since 1942. There would be a few minor tweaks over the next couple of decades, but they’re all stylistic. Carmine Infantino, Jim Aparo, Neal Adams, Marshall Rogers and Alan Davis all drew the same suit; the only difference is how long they like their ears. The result was Batman’s best and most iconic costume, which stuck around for a full 30 years for a very good reason. It’s got a striking color scheme, and once the logo is tweaked to have the curved wings that fit in the oval, it’s one of the best pieces of iconography in comics. It’s also very adaptable to different styles and levels of brightness. The Batman: The Animated Series trick of drawing the cape, cowl, and trunks black and using the traditional blue for highlights, for example, is an extremely good interpretation and the reigning, defending Best Batman. In other words, these are Batman’s real clothes. Everything else is just something he wore that one time.Tag Archives: Orange This is a simple and delicious cake that uses the whole orange, which I find exciting each time I make it. I like it with flaked almonds as well as the almond meal for the texture they add. It is … Continue reading →Q: Python: draw multiple figures in separate windows (same data but with different X range) I wonder how to plot data in separate figures (not multiple figures in one window). The issue is that I want to visualize the data along different X range. For example: import numpy as np import pandas as pd import matplotlib matplotlib.use('TkAgg') import matplotlib.pyplot as plt X=np.linspace(0,100,num=1000) Y=X2-X fig=plt.figure() plt.plot(X,Y) matplotlib.pyplot.xlim([0, 50]) plt.show() fig=plt.figure() plt.plot(X,Y) matplotlib.pyplot.xlim([50, 100]) plt.show() Here I get two separate figures. But I did the plt.plot() for the same data repeatedly. It can take time if the data is big. A: You can limit the range of data to plot, not only the viewing interval. To this end you may introduce a condition and filter the arrays to plot by that condition. import numpy as np import matplotlib matplotlib.use('TkAgg') import matplotlib.pyplot as plt X=np.linspace(0,100,num=1000) Y=X2-X ranges = [[0, 50], [50, 100]] for r in ranges: cond = (X >= r[0]) & (X <= r[1]) fig=plt.figure() plt.plot(X[cond],Y[cond]) plt.xlim(r) plt.show() State gasoline tax to drop July 1 FILE - This Feb. 27, 2012, file photo shows gas prices at a Pittsburgh Exxon mini-mart. Exxon Mobil's fourth-quarter profit fell 16 percent as the company produced slightly less oil and gas and its refining business weakened, the company announced on Thursday, Jan. 30, 2014. (AP Photo/Gene J. Puskar, File) The Associated Press FILE - This Feb. 27, 2012, file photo shows gas prices at a Pittsburgh Exxon mini-mart. Exxon Mobil's fourth-quarter profit fell 16 percent as the company produced slightly less oil and gas and its refining business weakened, the company announced on Thursday, Jan. 30, 2014. (AP Photo/Gene J. Puskar, File) The state Board of Equalization voted 5-0 on Tuesday in Culver City to reduce the per-gallon excise tax on a gallon of regular gasoline to 36 cents per gallon, a 3.5 cent per gallon drop. The tax goes down July 1. The decision comes a year after the board voted to raise the tax by 3.5 cents per gallon. Still, Californians pay among the highest gas taxes in the nation, at about 68 cents per gallon through federal, state and
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Let g = m + f. Is g a multiple of 12? True Let d(n) = 5n*2 + 55n - 64. Is d(14) a multiple of 7? False Let b be (1 - (-1)/(-2))/(18/36). Let x be b/(5 - (-45)/(-10)). Suppose 2y = 4p - xp + 406, 0 = y - 5p - 199. Is 34 a factor of y? True Let y be 6 + -2 + (-4)/(-1). Suppose -yq - 451 + 3907 = 0. Is q a multiple of 48? True Suppose t + 56 - 60 = 0. Suppose 0 = b - 4a - 4 - 43, 4b = ta + 236. Is b a multiple of 22? False Suppose -344 = -16w - 280. Let u be 1 - (-1 - (1 - 0)). Suppose -2f - f = un - 252, -n + wf = -104. Is n a multiple of 17? False Let o = 43 + -39. Let c(f) = -o - 2f + 4f*2 - 3f*2 + 7. Is 22 a factor of c(10)? False Let z(f) = -249f + 33. Let c be z(-3). Suppose 4u + 2p - 1042 = -0p, -3p + c = 3u. Is 41 a factor of u? False Suppose q + 5d = 18, 3d = -2q - 3 + 18. Does 27 divide (33/q)/(4 - (-55)/(-14))? False Let v = 4403 - 3438. Is v a multiple of 17? False Does 9 divide 539/(-147) - (-10514)/3? True Suppose 136 = 2u - 2s, 0 - 6 = 3s. Suppose 0 = -c + u + 78. Is c a multiple of 16? True Suppose -6n = -37 + 1. Is (-281)/(-3) + -2n/18 a multiple of 15? False Suppose 5h = o + 704, -4h - 4o + 511 = -57. Let m = 87 - h. Let i = -14 - m. Is 20 a factor of i? True Let z = 16514 - 5525. Does 27 divide z? True Let f(g) = 114g - 1373. Is f(33) a multiple of 9? False Let d(h) = -4h - 7 + 4h + 9h. Let z be d(2). Let m = 29 - z. Is 18 a factor of m? True Let f(c) = -37c + 1. Let j be f(6). Let k = j + 427. Does 21 divide k? False Let c(q) = -q2 + 17q - 48. Let j be c(14). Let r = 118 - j. Is 12 a factor of r? False Let d be (0 + -1)/(12/(-50292)3). Let m = d + -893. Is 36 a factor of m? True Suppose 4c = -2h + 9085 + 271, -5c = 5h - 23395. Suppose 15q - h = 7q. Is 45 a factor of q? True Let d be -3 + (426/4)/(14/28). Suppose 0r + 2r = 82. Suppose -r = q - d. Is 11 a factor of q? False Let p = 447 + 8473. Is p a multiple of 37? False Suppose 5m + 4q - 24960 = 0, 18m - 3q = 19m - 4992. Is 32 a factor of m? True Suppose -l + 706 = 2s + l, -25 = -5l. Suppose s = k + 5f - 3f, -5k + 1716 = 2f. Is k a multiple of 6? True Suppose 20 = 2h + 3h. Suppose -hy + 24 = 2s - 80, -2 = 2y. Is 18 a factor of s? True Is (1232/(-42) - 2)(-21)/2 a multiple of 7? True Let n = 37 - 105. Let b = n - -141. Let w = b + -41. Is 8 a factor of w? True Suppose 3i - 3172 = -4q, 0 = 5i + 4q - 2101 - 3191. Suppose -490 = -10v + i. Does 31 divide v? True Let i = -195 - -204. Suppose 0 = 5v + 5f - 3f - i, -2f - 15 = -3v. Does 3 divide v? True Let g(j) = -5j3 - 2j*2 - 2. Let x(q) = -q + 7. Let w be x(5). Suppose 6 = -3r - 3k, -k + 6 + 1 = -wr. Does 17 divide g(r)? False Let w(i) = 6i2 + 48i - 244. Does 34 divide w(-21)? True Let j = 2548 + 1086. Does 17 divide j? False Suppose 28i = 151 + 58789. Is i a multiple of 54? False Let a = 185 + -291. Let n = -25 - a. Let f = -78 + n. Is f a multiple of 3? True Let t = 78 - -30. Let k = -102 + t. Suppose ks - 45 = 207. Is s a multiple of 29? False Is 336/294 - 6/(-7) - -8586 a multiple of 9? False Suppose 0p + 13624 = 30p - 4p. Is 4 a factor of p? True Suppose -5r + 22 = -8. Let y = r - 0. Is 24 a factor of (-1070)/(-6) - y/(-9)? False Let r = 750 - 1512. Let m = -392 - r. Is 10 a factor of m? True Let u(w) = w*2 - 4w + 5. Let g be u(5). Suppose 0 = -3z + z + g. Suppose -o + 4 = 0, -8 = i + 2i - zo. Is 4 a factor of i? True Let q(m) = -33m*2 + 67m*2 - m - 31m*2 - 17. Let h be q(7). Does 24 divide (0 + 3)-1 + h? True Is ((-481962)/(-185))/(9/15) a multiple of 26? True Let u = -21008 + 22779. Is u a multiple of 23? True Let d be -2185/(-34). Let t(y) = -30y + 36. Let b(n) = 59n - 73. Let x(q) = dt(q) + 3b(q). Is x(12) a multiple of 19? True Suppose -5g = -25, 4j + 3g - 6 - 9 = 0. Suppose -r - 60 + 262 = j. Is 13 a factor of r? False Let s be 56/(-6)(1290/(-35) - 12). Let m = s - 137. Is 7 a factor of m? False Let u(v) = -77 - 101 + 12 + 28v. Is u(9) a multiple of 6? False Is (-25011)/(-3) + ((-16)/(-32))/((-2)/(-20)) a multiple of 194? True Let x(d) = -4933d - 978. Is 26 a factor of x(-10)? False Let k be 9 - 1 - 27/(6 - -3). Suppose -3d - 714 = -z - 0d, -kd = -3z + 2130. Is 15 a factor of z? True Let b(j) = 14j - 227. Let l be b(15). Let x(p) = -53p + 19. Does 20 divide x(l)? True Let n = -91 - -157. Let c(q) = -2q3 - 67q - 7q3 - q2 + nq + 29q3 + 2. Is 23 a factor of c(2)? False Suppose 3f = 2b - 393, 3b - 318 - 297 = -4f. Suppose 2q - 87 - b = 0. Does 24 divide q? True Suppose 2*p = g + 9
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841, 1841, 320, 8491, 16, 609, 795, 3022, 64, 17373, 13, 323, 352, 3133, 281, 479, 326, 253, 5323, 3746, 452, 21854, 942, 323, 811, 3161, 641, 13, 1805, 685, 247, 1569, 72, 2373, 275 ]	doubted that Socrates meant it, at least in its obvious sense: "Well then, I do not perceive what sort of thing you are saying is 'lawful,' or what sort 'just!'" (4.4.12–13). Socrates proceeded patiently to explain, through question and answer, that he was referring to the "lawful" in the obvious sense: the laws of any city. Hippias took this to mean what the citizens together set down in writing dictating what ought to be done and what ought not (since he speaks of the citizens and not of the multitude, or _d_ ē _mos_ , his definition of law covers all republican forms—aristocracy and "plutocracy" as much as democracy [see 4.6.12], and of course Sparta as much as Athens). Socrates accepted this, and then gained Hippias's agreement that the "lawful person" would be one partaking of civic life in accord with those written laws, and the "unlawful" would be one who violated them, and that the former would be doing just things, and the latter, unjust; and that "therefore, the lawful person is just, the unlawful unjust." Agreeing with all this (none of which entails the _identification_ of the just with the legal), Hippias expostulated: "But as for the laws (he said), oh Socrates!—how could one consider this a serious business, or obey these, when the very ones who establish them frequently reject and change them, upon scrutiny!?" (4.4.13–14). Precisely inasmuch as the sophist agreed that the law abiding is just, he could not take seriously either the just in this sense or the legal, as the true norms for a wise life (see the famous speech of Hippias in Plato's _Protagoras_ 337cff.). The rejoinder of Socrates was risibly sophistic, even demagogic—and therefore, as a chastening lesson for the famous sophist, most instructive. Asking (without allowing Hippias a chance to reply) if disparaging those who obey laws because the laws are often repealed is not equivalent to blaming those who fight well in war because peace later comes to pass, Socrates belligerently demanded: "So, are you also blaming those who with eager spirit take the field on behalf of their fatherlands in war!?" This outrageous imputation Hippias of course heatedly denied, swearing by Zeus (4.4.14). And Socrates then immediately launched into an uninterrupted speech. The monologue's first and shortest theme, expressed in two rhetorical questions, was the glory and the benefits that the city derives from having citizens obedient to law—as exemplified above all by Lycurgus's Sparta (4.4.15). The speech's second and somewhat lengthier theme was the public opinion of the Greek "cities" to the effect that that "the greatest good" is "concord" ( _homonoia_ ) among the citizens—meaning, as interpreted by "my thinking" (Socrates pointedly says here; cf. 4.6.14), concord that consists in obedience to the (city's) laws. "Without concord neither would a city be well governed nor a household nobly managed" (4.4.16). This is doubtless true; but does a household's concord _consist_ in obedience to the city's laws (see the _Oeconomicus_ )? At any rate, with the mention of the private household, Socrates segued to the third and much the longest theme of his monologue, the benefit to the "private individual" ( _idia_ ) of obedience to the laws, and the harm to the private individual of disobedience to the laws (4.4.17). Socrates listed, in the mode of anaphoric-rhetorical questions, no less than fourteen (or thirty-one, depending on how we count) private benefits, the first and foremost being avoidance of legal punishment (no small consideration for an itinerant foreigner like Hippias), and concluding with minimization of the number of one's enemies (the second half of the list is much preoccupied with the threat of and from one's enemies, and hence the need for friends and allies, in a state of war as well as peace; the previous praise of concord in lawfulness as a great civic good is thus followed by a spotlighting of the tenuousness of community; Socrates almost sounds like Hobbes). Socrates drew his personal conclusion: "I therefore [scil. because obedience to the law is beneficial in the ways stated, especially to private individuals], oh Hippias, show forth the lawful and just to be the same. But if you know things to be contrary, teach!" Of course, after this lengthy warning-reminder of the situation of individuals, including not least itinerant foreign individuals, in the cities, Hippias, vehemently swearing by Zeus, declared that he did not think that he knew anything contrary to what Socrates had been saying about the just (4.4.18; consider the public speech that Plato has Hippias report that he gives in various cities— _Hippias Major_ 286a). Hippias is no fool. So when Socrates moved to a new level, and asked, as regards the unwritten laws—which Hippias asserted to be conventionally observed in the same way in every land—if Hippias could declare that it is humans who have established these laws, Hippias of course replied no. He embraced the opinion that it is the gods who have established the unwritten laws for humans—adding, as his reason for this statement, the fact that the first of these laws among all humans is that there must be reverence for the gods. Hippias had no intention of being indicted for impiety in Athens or in any of the cities he visits. Accordingly, he made no reference, in this semipublic forum, to the causal power of nature as a source of such universal, unwritten norms, nor to any sort of normative natural right (contrast Plato, _Protagoras_ 337cff.). That such was in the back of his mind, however, became visible when Socrates proceeded to ask if it is not also conventionally held everywhere that parents must be honored, but that there is to be no sexual intercourse between parents and children. For Hippias could not bring himself to agree that the latter is a "law of god," because (he explained when questioned) he perceives people who transgress this law, with impunity. Was not Hippias conceiving of the truly universal human norms as being of such a character that, given human nature, human community is difficult to sustain without grave injury to itself and its members if these very minimal norms are not conventionally enforced? Conflict between positive human laws and these very basic, natural-conventional ( _nomikon phusikon_ ), norms or laws would be rare (Gray 2007, 9). Socrates seemed to be thinking along similar lines, though of course he too expressed his view in prudently religious terminology. For he replied that "those who transgress the laws laid down by the gods pay a penalty, which is in no way possible for a human to elude" (4.4.21). When Hippias skeptically demanded to know what was the character of this _inescapable_ "divine" penalty in the case of incest, Socrates adduced the purported biological fact of the likelihood that the sperm of men past or prior to their prime will produce defective offspring. "Who else (he said) would procreate badly, if these do not?!" This Socrates dared to declare " _the_ greatest penalty—by Zeus!" (4.4.22–23; there is at this point in the conversation an unprecedented and never-to-be-equaled flurry of Zeus-expletives by Socrates; here we have a peak of intensity of Xenophontic comedy). Xenophon and his Socrates might seem to have forgotten the very relevant fact that at the time Socrates died, the sixty-nine-year-old and his much younger wife had "very young" children (Plato, _Apology_ 34d and _Phaedo_ 116b). I am inclined to judge that this passage is a most perfect exemplification of the difference between Xenophontic and Aristophanean comedy. I note again that Shaftesbury (1964, 1: 167) refers to Xenophon as the "philosophical Menander." The serious point of Xenophon's comic production would be that he shows Socrates here, together with Hippias, presenting somewhat tongue in cheek a veiled version of a quite minimal, and not strict, conception of natural right (anticipating, we may note, the great Averroistic-Aristotelian conception that has played such an important role throughout the history of political philosophy since Aristotle). As W. K. C. Guthrie remarks, "It is noticeable that these arguments would apply equally to a world ruled not by gods but by an impersonal nature." Along these lines, Socrates went on to state the penalty for violating the universal convention dictating that one return good to those from whom one has received some benefit: the penalty is that in consequence, one becomes bereft of good friends, and has to seek out those who hate one. Swearing by Zeus, Hippias expressed his hearty agreement to "all" that Socrates had said, employing a curious formulation: "Socrates (he said), all these things befit/are _like_ gods, for it seems to me that the laws themselves have punishments for transgressors, better than a lawgiver in
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285, 6112, 8852, 13, 342, 253, 4585, 6299, 42419, 20, 283, 22, 5770, 16, 78, 63, 20, 13146, 12952, 6571, 432, 253, 2434, 16859, 15861, 267, 4752, 7121, 281, 253, 714, 1028, 37628, 22826, 13, 534, 37035, 253, 2170, 273, 690, 273, 253, 954, 33661, 11112, 63, 1012, 63, 36, 9043, 3825, 275, 776, 1263, 2170, 15, 380, 2169, 10410, 30604, 3672, 403, 2779, 2905, 281, 36680, 23281, 14800, 15, 380, 2553, 26556, 11112, 63, 1012, 63, 36, 21022, 310, 2779, 253, 906, 273, 33661, 36680, 6315, 3280, 432, 8281, 2685, 390, 1144, 37502, 460, 3275, 2879, 281, 17787, 3275, 13, 2581, 685, 1955, 281, 247, 11112, 63, 1012, 63, 36, 5802, 2380, 281, 8655, 4142, 273, 3625, 3275, 275, 253, 1527, 3617, 46, 15, 34129, 3086, 3625, 3275, 651, 2779, 906, 275, 253, 19133, 273, 11112, 63, 1012, 63, 36, 273, 3625, 18014, 984, 387, 2169, 7963, 23744, 4142, 1679, 14539, 6361, 6919, 318, 6634, 342, 1675, 281, 18224, 30770, 6315, 1309, 6315, 21746, 15, 496, 1635, 13, 8655, 23281, 4719, 476, 906, 275, 4067, 32587, 4488, 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835, 4942, 1698, 2553, 1824, 10410, 30604, 4620, 275, 253, 15109, 2460, 2470, 1470, 374, 1084, 2041, 15, 13269, 1036, 3141, 15, 72, 4699, 910, 709, 14, 881, 568, 926, 2536, 187, 187, 3138, 6648, 19703, 253, 8820, 9058, 273, 13803, 63, 1047, 63, 36, 2193, 5867, 432, 8187, 2553, 26556, 3530, 4880, 187, 24731, 4698, 13691, 476, 320, 11575, 327, 544, 1470, 337, 1084, 2041, 15, 13269, 1036, 3141, 15, 72, 2874, 910, 709, 14, 881, 568, 926, 986, 5774, 2041, 15, 13269, 1036, 3141, 15, 72, 4838, 4253, 2041, 15, 13269, 1036, 3141, 15, 72, 4838, 94, 187, 187, 510, 310, 5829, 2259, 3711, 273, 11112, 63, 1010, 63, 47, 275, 2553, 9043, 3825, 12957, 247, 4329, 13315, 9058, 342, 625, 33661, 11112, 63, 1010, 63, 47, 3672, 2540, 1475, 253, 309, 633, 406, 337, 8230, 483, 2670, 285, 253, 18012, 273, 253, 1264, 2201, 21646, 313, 40, 23151, 267, 6156, 14, 54, 2204, 317, 39078, 13, 2434, 16859, 15861, 267, 4752, 13, 17206, 12584, 3682, 10, 285, 625, 18839, 11112, 63, 1010, 63, 47, 3672, 275, 253, 12861, 12685, 13, 6146, 273, 253, 309, 633, 406, 337 ]	, and accounted for anisotropy. The best model for each variable was chosen based on their root-mean-squared-standardized values (closest value to 1). Natural breaks (Jenks) were used to classify the interpolated values into categories. These models were computed using the Geostatistical Analyst Wizard. Results and discussion {#sec003} ====================== Isotopic baseline of the sGoM surface sediment {#sec004} ---------------------------------------------- The first objective of this study was to determine baselines and trends in the isotopic composition of sedimentary organic matter across the sGoM. Surface sediment of all samples range in δ^13^C values from -22.4‰ to -19.9‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}) and have an average value of -21.2 ± 0.6‰ (standard deviation; n = 73), while Δ^14^C values range from -337.1‰ to -69.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and have an average of -164.6 ± 54.0‰ (n = 72). Surface sediment of all samples range in δ^15^N values from 2.8‰ to 7.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and have an average of 4.7 ± 0.9‰ (n = 66). The %C on a carbonate-free basis range in value from 0.65% to 3.89% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and average 1.45 ± 0.59% (n = 66), while %N range in value from 0.09% to 0.49% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 0.18 ± 0.07% (n = 66). In a data set consisting of only surface sediments from the multicores (0--1 cm section), δ^13^C values range from -22.2‰ to -19.9‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of -21.0 ± 0.6‰ (n = 41), while Δ^14^C range in value from -337.1‰ to -69.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of -164.3 ± 63.1‰ (n = 41). δ^15^N range in value from 3.7‰ to 5.3‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and average 4.6 ± 0.4‰ (n = 37). %C range in value from 0.95% to 3.89% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 1.57 ± 0.58% (n = 37), while %N range in value from 0.14% to 0.49% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 0.20 ± 0.07% (n = 37). Due to the lack of differences, determined by T-test, in the average %C, Δ^14^C and δ^15^N values and only slight significant differences for δ^13^C and %N values (0.33‰ and 0.04%, respectively) when examining all surface sediment samples vs. only multicore (0--1 cm section) samples, we treated all samples as being representative of surficial sediment. The isoscape map of δ^13^C surface sediment organic carbon values indicates the dominance of marine production with some terrestrial inputs in the nearshore. The map reveals more δ^13^C depleted areas in the south (Bay of Campeche) and towards the Laguna de Terminos ([Fig 1](#pone.0231678.g001){ref-type="fig"} area G). This area is described as a transitional area with terrigenous clastic sediments found west of the Yucatan shelf, along the continental shelf, and biogenic carbonate deposits located on the Yucatan shelf \[[@pone.0231678.ref046], [@pone.0231678.ref047]\]. Depleted δ^13^C areas are observed along the coast, west-south-west of the Ixtoc 1 site (reference location) where three major rivers terminate into the sGoM (Grijalva-Usumacinta, Coatzacoalcos, Papaloapan; [Fig 1](#pone.0231678.g001){ref-type="fig"} areas F, E & D). Depleted δ^13^C areas are also observed along the coast from north of Tampico ([Fig 1](#pone.0231678.g001){ref-type="fig"} area C) to the Texas coastline by Corpus Christi ([Fig 1](#pone.0231678.g001){ref-type="fig"} area A). More enriched δ^13^C areas are observed offshore, in deeper water. Soto and Escobar-Briones \[[@pone.0231678.ref048]\] determined that the food web of the inner shelf mostly receives estuarine input while the food web of the middle and outer shelf receives marine carbon sources. The δ^13^C isoscape map is similar to a map of chlorophyll concentration from a 2015 satellite imagery ([Fig 2](#pone.0231678.g002){ref-type="fig"}; \[[@pone.0231678.ref049]\]). This particular chlorophyll map is generally representative of chlorophyll at other times in the GoM. Higher concentrations of chlorophyll (0.8 to 5.0 mg/m^3^) are generally observed along the Mexican and Texas coast, with the highest concentrations (\~3--5 mg/m^3^) occurring mostly from the Coatzacoalcos River to the Yucatan shelf, which encompasses the area of some of the most depleted δ^13^C sediments in our study area. The higher chlorophyll areas are likely related to terrestrial nutrient inputs. The surface sediment δ^13^C depletion is likely the result of depleted terrestrial carbon input from river flow or estuarine production added to marine production, rather than due to a δ^13^C induced response to enhanced rates of primary production in the open GoM. Enhanced primary production would likely result in the enrichment of δ^13^C of primary producers because at higher photosynthetic rates less isotopic fractionation occurs with respect to dissolved inorganic carbon during carbon fixation. In addition, enhanced nutrient concentration can result in larger phytoplankton cells which are also associated with increasing δ^13^C enrichment \[[@pone.0231678.ref050]--[@pone.0231678.ref053]\]. ![Map of chlorophyll (mg/m^3^) in the Gulf of Mexico from August 9 to 15, 2015.\ Reprinted from the USF optical oceanography lab under a CC BY license, with permission from Chuanmin Hu, original copyright 2015.](pone.0231678.g002){#pone.0231678.g002} A related spatial trend is observed on the Δ^14^C isoscape map ([Fig 3](#pone.0231678.g003){ref-type="fig"}). The area surrounding the Ixtoc 1 blowout site and towards the Laguna de Terminos consists of more modern, Δ^14^C enriched carbon, likely influenced by the Laguna de Terminos estuarine production ([Fig 3](#pone.0231678.g003){ref-type="fig"} area G) and the Grijalva-Usumacinta Rivers ([Fig 3](#pone.0231678.g003){ref-type="fig"} area F), while offshore areas are more depleted in Δ^14^C. The two most depleted sites (\# 68; IXNW1600 and \# 73; 2392) are located in water depths greater than 3000 m. These areas likely experience slower sedimentation rates and slower input rates of photosynthetically fixed marine material delivered from the surface. Areas of Δ^14^C depletion are also observed along the coastline between the Papaloapan River and Panuco River ([Fig 3](#pone.0231678.g003){ref-type="fig"} area D and C) where relatively low surface water chlorophyll appears in the satellite image ([Fig 2](#pone.0231678.g002){ref-type="fig"}). ![Map displaying the spatial trend of Δ^14^C values analyzed from 72 surface sediment samples.\ Landmark legend can be viewed on [Fig 1](#pone.0231678.g001){ref-type="fig"}.](pone.0231678.g003){#pone.0231678.g003} The isoscape map of δ^15^N in surface sediments reveals a latitudinal trend with more depleted δ^15^N areas observed around the Ixtoc 1 blowout site and the outputs of the three major rivers (Grijalva-Usumacinta, Coatzacoalcos, Papaloapan) and more enriched δ^15^N areas in the deeper waters, north of the Ixtoc 1
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AI also will be used by sellers of consumer products to develop lending strategies and other potential financial products that are created to boost sales and to capture market share. These new types of financial services will not only face regulatory scrutiny, but will also surely be exploited to form the basis for class actions or other business torts and similar legal action. As noted above, data development and storage will continue to surge, triggering divergent and conflicting uses. These issues raise many traditional privacy concerns and will spawn new rounds of litigation. States will enact separate statutory schemes, which will trigger unique liability issues and place increased pressure on in-house counsel to manage related litigation risks and business strategies, as further discussed below. Apart from consumers, companies will collaborate on AI implementation across international platforms, leading to a whole host of licensing agreements and business contracts that will require a new set of skills to pursue effectively AI-based claims against a competitor that fall outside the traditional patent or trade secret dispute. Disputes that arise between companies in different countries will lead to increased use of arbitration and create opportunities for creative dispute resolution strategies and a greater need for in-house counsel to manage the related business risks. To protect against civil liability, regulatory scrutiny, and reputational harm from unintended outcomes across a wide-variety of AI usage, companies need to support their AI strategies with governance structures designed and overseen by humans. The components of an effective governance strategy will differ by industry and application, but key pillars can include: Robust quality control protocols to test that those algorithmic decisions are producing outcomes that can be fairly expected by companies and their customers. The deployment of AI throughout numerous industries will put strain traditional infrastructure and systems that exist to manage litigation risks across key business platforms and create an urgent need for new protocols. These protocols should be risk based; more consequential applications (e.g., decisions impacting healthcare or personal finance) should be more tightly overseen than those with less impact on consumers (e.g., recommendations for products or entertainment content that a consumer might like based on prior purchases). Policies and procedures to reduce the risk that algorithmic training data at the front end and outcomes at the back end are infected by unintended biases, particularly in the consumer, financial, housing, and employment contexts. Commitments to transparency and accountability. Companies should consider when and how to give notice (to consumers and business partners) that decisions impacting them will be made on an automated basis. Companies should also consider creating procedures for redress when a consumer believes he or she has been treated unfairly by an algorithmic decision-making process. Internal qualifications requirements for AI operators. This will demonstrate responsible oversight by ensuring that only qualified individuals with the right technical competencies are employed in AI-related positions. Statements of values and ethics. Just as companies often express the general principles that drive their businesses, an increasing number are now articulating those principles that animate and surround their development and deployment of AI. This can include statements emphasizing commitments to quality outcomes, consumer privacy, safety, unbiased and fair decisions, and transparency around the use of AI. VIII. Conclusion and a Look Ahead The economic and societal benefits of AI will be profound, but so too are the risks and people’s concerns about how automated processes will impact them and their families. As companies deploy AI-driven services and products, they need to expect that these risks and concerns will manifest in various forms of litigation, regulatory enforcement, and protest, placing a premium on the ability to understand and explain artificial intelligence and the decisions that the owners of a business make to implement this technology. Creating and constantly refining sound governance principles at the ground level will help companies answer these concerns and comply with existing legal regimes—and ultimately mitigate their potential for undermining business objectives and triggering legal liability. Conducting this front-end compliance and governance work under the attorney-client privilege is an essential process to ensure that businesses can ask the hard questions, make the difficult risk-based decisions, and proceed with confidence. Please contact any of the authors, or your usual contact at Paul Hastings, to ask further about the ways we are helping our clients navigate their AI-related development, growth, and compliance strategies.Q: How to add two or more buttons to annotationView: MKAnnotationView? I want to have a MKAnnotationView to my pins on map (using MapKit) with next attributes: 1) image 2) details button 3) another details button 4) another details button? I have done actually adding image and details button with next code: annotationView.detailCalloutAccessoryView = snapshotView // snapshot view is a custom view // with image and its constraints let detailsButton = UIButton(type: .detailDisclosure) annotationView.rightCalloutAccessoryView = detailsButton So, the question is how to add more than one button to MKAnnotationView? Because all the tutorials that I've ever seen only is "how to add details button". A: I have done it From documentation left and right calloutAccessoryView are low width and height. So, we can add buttons and image only in detailCalloutAccessoryView. Here is my code. It's working. I haven't done a review. Because it's more clear for understanding. func mapView(_ mapView: MKMapView, didSelect view: MKAnnotationView) { if !(view.annotation! is MKUserLocation) { let customPin = view.annotation as! CustomPin self.spotDetailsForSendToPostsStripController = customPin.spotDetailsItem // its for sending to another controller. configureDetailView(annotationView: view, spotPin: customPin.spotDetailsItem) } } func mapView(_ mapView: MKMapView, viewFor annotation: MKAnnotation) -> MKAnnotationView? { if annotation is MKUserLocation { return nil } if !(annotation is CustomPin) { return nil } let identifier = "CustomPin" var annotationView = mapView.dequeueReusableAnnotationView(withIdentifier: identifier) if annotationView == nil { annotationView = MKPinAnnotationView(annotation: annotation, reuseIdentifier: identifier) annotationView?.canShowCallout = true } else { annotationView!.annotation = annotation } return annotationView } func configureDetailView(annotationView: MKAnnotationView, spotPin: SpotDetailsItem) { let width = 250 let height = 250 let snapshotView = UIView() let views = ["snapshotView": snapshotView] snapshotView.addConstraints(NSLayoutConstraint.constraints(withVisualFormat: "H:[snapshotView(250)]", options: [], metrics: nil, views: views)) snapshotView.addConstraints(NSLayoutConstraint.constraints(withVisualFormat: "V:[snapshotView(250)]", options: [], metrics: nil, views: views)) let imageView = UIImageView(frame: CGRect(x: 0, y: 0, width: width, height: height - 40)) // configure button1 let button1 = UIButton(frame: CGRect(x: 0, y: height - 35, width: width / 2 - 5, height: 35)) button1.setTitle("Info", for: .normal) button1.backgroundColor = UIColor.darkGray button1.layer.cornerRadius = 5 button1.layer.borderWidth = 1 button1.layer.borderColor = UIColor.black.cgColor button1.addTarget(self, action: #selector(MainFormController.goToInfo), for: .touchDown) // configure button2 let button2 = UIButton(frame: CGRect(x: width / 2 + 5, y: height - 35, width: width / 2, height: 35)) button2.setTitle("Posts", for: .normal) button2.backgroundColor = UIColor.darkGray button2.layer.cornerRadius = 5 button2.layer.borderWidth = 1 button2.layer.borderColor = UIColor.black.cgColor button2.addTarget(self, action: #selector(MainFormController.goToPosts), for: .touchDown) // configure image let image = UIImage(contentsOfFile: "plus-512.gif") imageView.image = image // implement your own logic imageView.layer.cornerRadius = imageView.frame.size.height / 10 imageView.layer.masksToBounds = true imageView.layer.borderWidth = 0 imageView.contentMode = UIViewContentMode.scaleAspectFill // adding it to view snapshotView.addSubview(imageView) snapshotView.addSubview(button1) snapshotView.addSubview(button2) annotationView.detailCalloutAccessoryView = snapshotView } func goToPosts() { print("go to posts") // your implementation(segues and etc) } func goToInfo() { print("go to info") // your implementation(segues and etc) } CustomPin
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Soit qu'elle contractât avec les cités fédérées ou d'autres villes des conventions de droit privé international (δίϰαι άπὸ συμбόλων), soit qu'elle s'en tînt à des relations réglées par la coutume, elle cherchait à faire prévaloir ce principe de droit consulaire, que le demandeur devait plaider dans la ville du défendeur . Mais, comme les Athéniens en étaient les mauvais marchands , ils se virent obligés de restreindre l'application de ce principe, en exigeant que pour tout contrat conclu à Athènes le tribunal athénien fût seul compétent . Poussant jusqu'au bout la politique d'unification, Athènes prétendit imposer à l'empire son système de poids, mesures et monnaies. D'elles-mêmes, les petites villes avaient cessé, des leur entrée dans la confédération, de frapper d'autres pièces que le billon nécessaire au marché local. Plusieurs grandes villes coupables de défection se virent enlever une prérogative attachée à la souveraineté. En fait, les « chouettes » du Laurion étaient à peu près les seules monnaies d'argent que les matelots de la flotte rapportaient dans les villes et que les villes renvoyaient sous forme de tribut ; le talent et le pied attiques étaient familiers aux marchands de tous les ports. Un décret, proposé par un nommé Cléarchos, prescrivit à toutes les cités de l'empire l'usage exclusif des étalons athéniens et leur fit défense de frapper de la monnaie d'argent. Il faut croire que le décret rencontra des résistances sérieuses, car il en fallut un second (avant 420) pour ordonner aux particuliers d'échanger l'argent étranger contre de l'argent attique . Par ce complet mépris de tout ce qui rappelait l'autonomie, l'empire d'Athènes parut à ses sujets une tyrannie. Les Athéniens étaient les premiers à le dire ; ils justifiaient leur politique en invoquant avec Périclès les services qu'ils avaient rendus et continuaient de rendre, ou bien en déclarant avec la brutalité d'un Cléon que, sur la voie où l'on était engagé, il n'y avait plus à revenir en arrière, mais à briser tous les obstacles. Et ainsi, les cités qui s'étaient unies pour assurer leur liberté se sentaient asservies, et un Athénien pouvait s'indigner qu'on les traitât comme esclaves à la meule . Elles payaient tribut pour embellir Athènes et enrichir sa déesse. Elles étaient obligées d'envoyer des délégués aux Dionysies pour y apporter la somme exigée, aux Panathénées pour offrir des victimes au prix fort, aux fêtes d'Éleusis pour consacrer aux déesses les prémices de la récolte annuelle . Elles étaient maintenues dans le droit chemin de la démocratie, contraintes à l'obéissance et à la fidélité par les archers et les hoplites qui campaient sur leur acropole, par les trières qui stationnaient dans leur port, par les clèrouques établis par milliers sur leur sol. Le mécontentement couvait dans toutes les parties de l'empire. Longtemps il fut impuissant : à des cités isolées, séparées par de grandes distances, tout effort collectif était impossible contre les maîtres de la mer. Enfin les Spartiates donnèrent le signal de la grande lutte contre Athènes ; dès le premier jour ils proclamèrent la guerre de délivrance. De fait, l'empire devait succomber moins encore sous les attaques furieuses dirigées du dehors que par le travail de sape exécuté sans relâche par les ennemis de l'intérieur. L'autonomie se vengeait d'une centralisation odieuse pour des Grecs. Elle était tellement intraitable, cette autonomie des petites cités, qu'elle n'admettait même pas aussi facilement qu'on pourrait le croire la solidarité internationale des partis. Cléon ne comprend pas qu'on distingue, parmi les Mytiléniens rebelles, les démocrates des oligarques : pour lui, ils sont tous également coupables . Et, quand on demande au peuple athénien, par mesure de salut public, de permettre aux villes alliées un changement de constitution dans le sens oligarchique, Phrynichos s'y oppose. À quoi bon ? « Ce ne serait ni un motif de soumission pour les cités révoltées, ni un gage de fidélité pour celles qui nous restent ; car, plutôt que d'être esclaves de l'oligarchie ou de la démocratie, elles préfèrent être libres sous n'importe lequel de ces gouvernements . » Pourtant l'impérialisme des Athéniens n'était que prématuré et ne fut pas inutile. La grande faute d'Athènes – faute inévitable à cette époque – est de n'avoir pas compris que, si elle faisait brèche dans le droit des autres cités, elle devait leur ouvrir largement le sien. Sous le coup de la défaite, des esprits audacieux y songèrent ; mais il était déjà trop tard, et l'on attendit encore les désastres suprêmes pour faire une application exceptionnelle et désespérée d'une idée que Rome un jour rendra si féconde . Telle quelle, la tentative de Périclès et de ses successeurs a eu de grands résultats, non pas seulement pour Athènes, qui n'aurait pas laissé un si grand nom, si elle n'avait pas été la capitale d'un si grand empire, mais pour l'empire lui-même et pour toute la Grèce. Ce sont les vices du système qui attirent toujours l'attention, parce que les anciens n'ont jamais vu et qu'à leur suite les modernes ne regardent guère que le côté politique des événements. Mais à d'autres points de vue, et même à celui-là, l'empire athénien a rendu les plus grands services en créant de précieux éléments d'unité. Par l'intermédiaire des cités confédérées, la démocratie a, malgré tout, fourni à l'ensemble des Grecs un modèle qui n'a plus cessé de s'imposer. Grâce au libéralisme commercial auquel les Athéniens ne renonçaient en pleine guerre que pour assurer leur subsistance et se procurer des matériaux de construction navale, le bassin de la Méditerranée constituait un marché unique dont l'exploitation n'enrichissait pas seulement le Pirée . Et puis, tous ces alliés qui venaient chaque année aux représentations des Grandes Dionysies et aux processions des Panathénées rapportaient chez eux et répandaient partout le goût d'une littérature et d'un art supérieurs. Enfin, de même que la France vaincue en 1815 a laissé à ses vainqueurs le code Napoléon, Athènes, avant d'être écrasée, avait répandu chez les confédérés qu'elle traînait devant ses tribunaux les principes de sa législation, si bien que beaucoup d'entre eux adoptèrent pour toujours, non pas seulement la technique de son droit, mais ses principes de liberté et de responsabilité personnelles . Ainsi, par la domination qu'elle exerça pendant trois quarts de siècle, Athènes fit beaucoup pour l'unification politique et économique, intellectuelle et juridique de la race grecque.
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17451, 45096, 13, 7654, 980, 13, 285, 2661, 74, 15, 11928, 5305, 476, 1361, 281, 1980, 907, 253, 45644, 17451, 84, 285, 3653, 253, 12147, 273, 10171, 15, 308, 18, 285, 308, 19, 56, 6430, 10313, 253, 39897, 23322, 2544, 273, 34512, 13, 40183, 4702, 13, 285, 20280, 14300, 275, 1635, 281, 2661, 74, 15, 5779, 14, 21272, 2544 ]	Transportation Commission of Southern Nevada. “Some of these visions may eventually come to fruition. But we are not talking about them happening in the next five years even, some of them in the next 10 years.”Dedicated to delivering the best IT support for Charities Our Approach to Managed IT Support for Charities At Premier Charity Solutions, we believe that our managed support helpdesk and consultancy services are the most important part of our partnership with your charity. Our customers (including Age UK, Mencap and The FSI) share that opinion. Whether large or small, your charity relies on your IT infrastructure to carry out the work you do. Faced with tight budgets that make wasted time more costly than ever, it is essential to choose a provider with a proven track record in the third sector and a good understanding of the needs and struggles of your organisation. That's why we pride ourselves on having an industry leading IT support and consultancy services tailored to the charity sector. Our recruitment process focuses on hiring personable staff with a passion for IT – making our helpdesk more approachable and encouraging your users to develop relationships and trust with our service desk. Rather than having auto-attendants, receptionists or voicemail systems, the telephone number provided to our clients goes directly to our support team. Your Dedicated Account Manager has previously worked on our helpdesk and projects teams, giving them a unique insight into the support, planning and implementation of your charity's IT systems. Their focus is to reduce your reliance on the helpdesk services by assessing and developing the systems your staff use, leading to improved reliability and efficiency. We work hard to build an IT partnership with our charities, rather than just a support arrangement. comprehensive site survey & IT audit We carry out a full site survey of your IT hardware, software and services, including a consultation with yourselves and your staff. We detail your charity’s existing IT infrastructure and discuss any additional requirements and ongoing / outstanding problems. Best practice analysis Once we have collated all of the information from the site survey of your charity, your dedicated account manager will contact you to arrange your Best Practice Analysis. This is a detailed document providing information on any areas of concern with your existing system as well as information on security, compliance and business continuity. We also specify any upcoming renewals or out-of-date solutions and provide information on forthcoming technologies and services that may benefit your charity. Pro-active real time monitoring Pro-active real-time monitoring and reporting enables us to detect and resolve many support issues before they impact your charity. We monitor every server, device and cloud service using a multitude of alerting, monitoring and reporting tools. facilities & update management All new, change and remove user requests are managed to ensure organisational compliance and identified to provide change tracking and reporting. This also includes software update control, data backup, restoration, server maintenance (automated as well as manual) and administration. third party software & hardware vendor support Where authorised, we will liaise with all your third-party hardware, software, telecommunications and cloud service providers on your behalf. This gives you one point of contact for all IT related issues and requests, saving your staff time, as well as the frustration of being pushed between service providers – and allowing us to have a full audit trail for all services and supplier requests. Dedicated account management Your dedicated account manager will contact you periodically to arrange a meeting or a call to discuss various aspects of your agreement, including feedback on our support team, a review of your ticket and service history, any noted areas of concern, completed / upcoming projects and any future requirements or new technologies. Having trouble with your IT? Transition process Site Survey & IT Infrastructure Audit A full site survey of your IT hardware, software and services including consultation with yourselves and your staff. We detail your existing IT infrastructure and discuss any additional requirements and ongoing / outstanding problems; please collate as much information as possible prior to the survey. Support: Online! That’s it! No problem too big or too small, start calling our team today! Following the site survey, we will have everything we need to start providing you with a fully managed helpdesk! Remaining Information Requested from Suppliers Just like switching your gas or electricity we do all of the hard work, contacting previous IT suppliers and 3rd party vendors, requesting information, detailing equipment, obtaining password etc. and all you have to do is to continue doing what you do best; running your organisation! Concerned your previous supplier’s wont hand everything over in a timely manner? Don’t be, we will liaise with your previous supplier directly and in the event they don’t provide the information requested, your dedicated project lead will reset any outstanding passwords and re-configure any equipment, software or services! Best Practice Analysis Once we have collated all of your information following your site survey, your dedicated account manager will contact you to arrange your Best Practice Analysis. This is a detailed document providing information on any areas of concern with your existing system, notification of any upcoming renewals or out-of-date solutions, as well as information on forthcoming technologies and services that may benefit your organisation. Regular Account Review Meetings & Consultancy Our account manager will contact you periodically to arrange a meeting or a call to discuss various aspects of your agreement, including feedback on our support team, a review of your ticket and service history, any noted areas of concern, completed / upcoming projects and any future requirements or new technologies Service Desk Statistics Average Telephone Response Time: 8 Seconds % SLA Target Hit: 99.6% % Incidents Resolved on Initial Contact: 76% % Incidents Resolved Without Escalation: 84% % Incident Tickets Re-Opened: 2.1% % Incidents Escalated to On-Site Engineer Visit: 0.3% Our Partners Get your quote now Name* Email Address* Telephone* Company Name Number of Users* Details* Marketing Permissions Premier Charity Solutions will use the information you provide on this form to be in touch with you and to provide updates and marketing. Please let us know all the ways you would like to hear from us: EmailDirect MailCustomised online advertising You can change your mind at any time by clicking the unsubscribe link in the footer of any email you receive from us, or by contacting us at [email protected]. We will treat your information with respect. For more information about our privacy practices please visit our website. By clicking below, you agree that we may process your information in accordance with these terms. We use MailChimp as our marketing automation platform. By clicking below to submit this form, you acknowledge that the information you provide will be transferred to MailChimp for processing in accordance with their Privacy Policy and Terms.Development of nonstoichiometric CuInS₂ as a light-harvesting photoanode and catalytic photocathode in a sensitized solar cell. A simple one-pot approach was developed to obtain nonstoichiometric CuInS2 nanocrystals. Using this approach, both In-rich and Cu-rich CuInS2 nanocrystals could be reliably synthesized by tuning stoichiometric combinations of [Cu]/[In] precursor constituents. By designing Cu-rich CuInS2 heteronanostructures to serve as counter electrodes, quantum-dot-sensitized solar cells (QDSSCs) equipped with In-rich CuInS2 and CdS cosensitizers delivered a power conversion efficiency of 2.37%, which is significantly more efficient than conventional Pt counter electrodes. To the best of our knowledge, this study represents the first report utilizing nonstoichiometric CuInS2 nanocrystals as a photon-harvesting sensitizer comprised of a photoanode and photocathode in QDSSCs; also unique to this report, these nonstoichiometric CuInS2 nanocrystals were formed by simply changing the cationic molar ratios without complicated precursor preparation. Impedance spectroscopy and Tafel polarization indicated that these Cu-rich CuInS2 heteronanostructures had electrocatalytic activities (used for reducing S(2-)/Sn(2-)) that were superior to a Pt catalyst. Moreover, we demonstrated that Cu-rich CuInS2 heteronanostructures were also useful counter electrodes in dye-sensitized solar cells, and this finding revealed a promising conversion efficiency of 6.11%, which was ∼96% of the efficiency in a cell with a Pt-based counter electrode (6.32%).MRI of oriental cholangiohepatitis. Oriental cholangiohepatitis (OCH) also called recurrent pyogenic cholangitis is characterized by intrahepatic duct calculi, strictures, and recurrent infections. In turn cholangitis can result in multiple hepatic abscesses, further biliary strictures, and in severe cases, progressive hepatic parenchymal destruction, cirrhosis, and portal hypertension. Magnetic resonance cholangiopancreatography (MRCP) and conventional T1-weighted (T1W) and T2-weighted (T2W) magnetic resonance imaging (MRI) findings have been described in patients with OCH. MRCP findings include duct dilation, strictures, and calculi. MRCP can help to localize the diseased ducts and determine the severity of involvement. T1 and T2W sequences reveal the parenchymal changes of atrophy, abscess formation, and portal hypertension in addition to calculi. Post-treatment changes
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878, 15, 285, 368, 476, 873, 697, 1318, 751, 2490, 686, 15597, 15032, 15, 3633, 7050, 3463, 1838, 1587, 357, 2428, 6788, 2877 ]	not best developers) win contracts. ~~~ shawkinaw So we have a choice between corruption and incompetence ... I'm pretty sure that corruption would actually be better, at least shit would work. ~~~ thebulge We only have a choice of which we want to start with. Eventually we end up with both. ------ coherentpony No shit. This whole ordeal has been nothing short of a complete and utter fucking disaster. And how much did the government pay to have this work done [1]? This is procurement at its finest. The government could have easily paid 10% of what they did to a tech start-up who would have done a much better job utilising scalable technologies. [1] [http://www.washingtonpost.com/blogs/fact- checker/wp/2013/10/...](http://www.washingtonpost.com/blogs/fact- checker/wp/2013/10/24/how-much-did-healthcare-gov-cost/) ~~~ Iftheshoefits I rather think that depends on what technological expertise the the start-up brought to bear on the problem. I understand it's chic to think that Healtcare.gov is "just another website", especially among a certain crowd who think that all development is web development, and best done on a MacbookPro using RoR/node/<functional language Y>/Go + <insert fad-of-the-day JS framework here>. It's a mistaken impression, though, because we aren't talking about some from-scratch system. We're talking about communication with and between a lot of legacy systems requiring what is almost certainly a frankenstein-like nightmare of patchwork APIs that dive into programming languages and styles hipster 20-somethings at hot S.F. Start Up X wouldn't understand because it's beneath them (I'm exaggerating and generalizing here for effect--this isn't to impugn all 20-somethings, start- ups, etc.). Honestly I don't think there is any contractor who could have pulled this project off flawlessly, or even very much better than the group of misfits who did Healthcare.gov did, just because of the sheer complexity of the project compounded with the increased politically-motivated interference from government officials that comes with such high-profile projects. ~~~ MichaelApproved > Honestly I don't think there is any contractor who could have pulled this > project off flawlessly A few flaws could be excused but the site was a disaster. > or even very much better than the group of misfits who did Healthcare.gov In just a couple of months, the current contractor group was able to clean up most of the mess and improve the site dramatically. In just _two months_! Imagine what they could have pulled off if the group was put together earlier. ~~~ Iftheshoefits The were able to clean up and improve an existing system, yes. That doesn't imply anything about their abilities to have created it from the ground up. ~~~ MichaelApproved To me, it implies they have even more ability than if I saw them build it from the ground up. They were able to read the garbage written by the other developers and make something useful out of it. Pretty impressive! ------ hga Too many lies in this article to take more from this than the bare fact that CGI Federal will be replaced by Accenture (the latter of which is no prize from what I've heard). I.e. the government's Centers for Medicare and Medicaid Services (CMS) were notoriously the "prime contractor" until the 3rd week of October (when replaced by contractor QSSI, also responsible for the "data hub"), and the attacks on the contractors are misplaced when their management was so impossibly bad. The linked _Washington Post_ article is not great, but better: [http://www.washingtonpost.com/politics/obama- administration-...](http://www.washingtonpost.com/politics/obama- administration-to-end-contract-with-cgi-federal-company-behind- healthcaregov/2014/01/10/001eb05a-719e-11e3-8b3f-b1666705ca3b_story.html) ~~~ coldcode Accenture taking over is like replacing dumb & dumber with larry, moe and curly. ------ greg5green >>Accenture, which is one of the world’s largest consulting firms, has extensive experience with computer systems on the state level, and it built California’s new health insurance exchange. Hasn't California's exchange had big problems too? ~~~ angersock Accenture is Arthur Andersen, and they've got a long history of extracting maximum value for shareholders from government contracts (state and local). EDIT: Arthur Andersen spawned Andersen Consulting spawned Arthur Anderson Business Consulting spawned Accenture. Some of AABC splintered off and joined Hitachi Consulting, some went elsewhere. The history of computer consulting is varied, interesting, and tragic. ------ patrickg_zill Am I the only one who thinks that the failures were intentional - that the whole mix-up is a passive-aggressive way of herding the USA into eventual single-payer? If Washington DC is, in fact, really that stupid and it is not intentional, under what strange notion of justice am I to pay taxes to these morons? ~~~ smsm42 Depends on what you mean by intentional. I'm not sure if the guys that call the shots are Machiavellian enough for such things - given how incompetent they are in everything else, hard to imagine they would be super-competent in long-reaching plots. If they had been able to execute long-running plans of such magnitude with such certainty, they wouldn't screw up so many things so badly as they had. However, the resulting vector of their efforts and failures may very well point into that direction, and not without their cooperation and help, since once they beat insurance industry into full dependency and make the population rely on subsidized care, the next logical step would be to eliminate the middlemen - there would be no point for them to exist anymore, at least not as independent entities - given that they would have no independence as such and serve no useful function in such setup. ------ bane One of the differences between creating and enforcing laws and creating software is that software _actually_ has to work. The efficacy of a law is open to endless debate, and it doesn't actually have to end up with any intended effect. But software, you can't legislate software. It's obvious that government shouldn't be in the software business, and the government would agree "that's why we use contractors for this!". But when 100% of your revenue comes from the government, in a way you're basically the same thing. ------ protomyth The government isn't exactly doing too well with any of its software projects. The IRS had problems during tax season and the FBI has cancelled and restarted multiple times. The Dept of Interior has been held in contempt of court for how bad their systems have been. ------ dreamfactory2 Talk about going from the frying pan to the fire. ------ wehadfun I here the points about about legacy systems. How much would it have cost to scrap those old systems and build from the ground up. ------ sciguy77 Is anyone surprised by this? ~~~ larockt Slightly surprised, but only because I would have thought that the company had kept up their payments to the necessary campaign funds. Q: Copy from excel and paste into online form Firstly may I apologise for the fact that I am not the best with computers, I have quite a large excel sheet for which I have to copy and paste 10 columns per row into an online form. Is it possible to create a macro for this and if yes how can I do so. Also please keep in mind that I am at work, so I'm limited from the use of plugins and I unfortunately have to use internet explorer. Your help would be much adored, Thank You A: Yes it is possible. You can use IE to automate this using vba. Sub xtremeExcel() Dim HTMLDoc As HTMLDocument Dim oBrowser As InternetExplorer sURL = "*****Paste URL Here**********" Set oBrowser = New InternetExplorer oBrowser.Silent = True oBrowser.navigate sURL oBrowser.Visible = True Do Loop Until oBrowser.readyState = READYSTATE_COMPLETE Set HTMLDoc = oBrowser.document 'Use firebug to identify the textbox or object you need. and you can set its value like 'HTMLDoc.GetElementByID("abcd").value
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The party's youthful leader, Viktor Orbán, was named prime minister. The electorate grew increasingly hostile to Fidesz-MPP's strongly nationalistic rhetoric and unseated the government in April 2002, returning the MSZP, allied with the SZDSZ, to power under Prime Minister Péter Medgyessy, a free-market advocate who had served as finance minister in the Horn government. In August 2004, amid revelations that he had once served as a counterintelligence officer, Medgyessy resigned and Sports Minister Ferenc Gyurcsány of the MSZP was named premier. Hungary became a fully fledged member of NATO in 1999 and, with nine so-called accession countries, was admitted into the EU in May 2004. Alan Parker's 1996 film _Evita_ was filmed in Budapest. The Buenos Aires cathedral on screen is the Basilica of St Stephen, the grand, tree-lined boulevard is Andrássy út and the swarthy horse guards belong to the Hungarian mounted cavalry. ## At Home at Last Reappointed prime minister in April 2006 after the electorate gave his coalition 55% of the vote, Gyurcsány began a series of austerity measures to tackle Hungary's budget deficit, which had reached a staggering 10% of GDP. But in September, just as these unpopular steps were put into place, an audiotape recorded shortly after the election at a closed-door meeting of the prime minister's cabinet had Gyurcsány confessing that the party had 'lied morning, noon and night' about the state of the economy since coming to power and now had to make amends. Gyurcsány refused to resign, and public outrage led to a series of demonstrations near the Parliament building in Budapest, culminating in widespread rioting that marred the 50th anniversary of the 1956 Uprising. After that violent demonstrations became a not-infrequent feature on the streets of Budapest and other large cities, especially during national holidays. The radical right-wing nationalist party Jobbik Magyarországért Mozgalom (Movement for a Better Hungary) has been at the centre of many of these demonstrations and riots. Gyurcsány led a feeble minority government until general elections in 2010 when Fidesz-MPP won a majority of 52% in the first round of voting and joined forces with the Christian Democratic People's Party (KDNP) to rule with a two-thirds majority in parliament Hungary's most recent appearance on the world stage came in 2011 when it assumed presidency of the EU Council. A new constitution came into effect at the start of 2012. In the April 2014 national elections, the first since constitutional changes reduced voting to a single poll and the number of MPs from 386 to 199, Fidesz took almost 45% of the vote and 133 seats, returning Orbán to the premiership. Orbán was clearly in charge once again but 'Viktátor', as the opposition press nicknamed him, was frequently criticised for strong-armed tactics and abuse of power. At the time of research Orbán was still at the helm but his ship did not appear to be on course. In 2007 János Kádár's grave in Budapest's Kerepesi Cemetery was broken into and his skull and assorted bones were removed. The only clue was a note that read: 'Murderers and traitors may not rest in holy ground 1956–2006'. The remains have never been recovered. #### Timeline AD 106 Roman Aquincum in today's Óbuda becomes the administrative seat of the province of Pannonia Inferior and a fully fledged colony less than a century later. Late 430s Aquincum offers little protection to the civilian population when the Huns burn the colony to the ground, forcing the Romans and other settlers to flee. 896–98 Nomadic Magyar tribes set up camp in the Carpathian Basin, with five of the seven original tribes settling in the area that is now Budapest. 955 Hungarian raids outside the Carpathian Basin as far as Germany, Italy and Spain are stopped for good by German king Otto I at the Battle of Augsburg. 1000 Stephen (István in Hungarian) is crowned 'Christian King' of Hungary at Esztergom on Christmas Day; he is canonised as St Stephen in 1083. 1222 King Andrew II signs the Golden Bull, according the nobility increased rights and powers; it is renewed nine years later. 1241–42 Mongols sweep across Hungary, reducing the national population by up to a half and killing some 100,000 people in Pest and Óbuda alone. 1458–90 Medieval Hungary enjoys a golden age under the enlightened reign of King Matthias Corvinus and Queen Beatrix, daughter of King Ferdinand I of Naples. 1514 A peasant uprising is crushed, with 70,000 people executed, including leader György Dózsa, who dies on a red-hot iron throne fitted with a scalding crown. 1526 Hungary is soundly defeated by the Ottomans at the Battle of Mohács and young King Louis is killed; the ensuing Turkish occupation lasts more than a century and a half. 1541 Buda Castle falls to the Ottomans; Hungary is partitioned and shared by three separate groups: the Turks, the Habsburgs and the Transylvanian princes. 1686 Austrian and Hungarian forces backed by the Polish army liberate Buda from the Turks; peace is signed with the Ottomans at Karlowitz (now in Serbia) 13 years later. 1703–11 Ferenc Rákóczi II fights and loses a war of independence against the Habsburgs; he is given asylum in Thrace by the Turkish Sultan Ahmet III. 1795 Seven pro-republican Jacobites, including the group's leader Ignác Martonovics, are beheaded at Vérmező (Blood Meadow) in Buda for plotting against the Habsburg throne. 1848–49 During the War of Independence, poet Sándor Petőfi dies fighting, Lajos Batthyány and 13 of his generals are executed for their roles and Lajos Kossuth goes into exile. 1867 The Act of Compromise creates the Dual Monarchy of Austria (the empire), based in Vienna, and Hungary (the kingdom), with its seat at Budapest. 1896 The millennium of the Magyar 'conquest' of the Carpathian Basin is marked by a major exhibition in City Park that attracts four million people over six months. 1918 Austria-Hungary loses WWI in November and its political system collapses; Hungary declares itself a republic under the leadership of Count Mihály Károlyi. 1919 Béla Kun's Republic of Councils, the world's second communist government after the Soviet Union's, lasts for five months until Kun is driven into exile by the Romanian army. 1920 Treaty of Trianon carves up much of Central Europe, reducing Hungary's territory by almost two-thirds and enlarging the ethnic Hungarian populations in Romania, Yugoslavia and Czechoslovakia. 1939 Nazi Germany invades Poland; Britain and France declare war on Germany two days later but Hungary remains neutral for two years when it joins the Axis led by Germany and Italy. 1944 Germany invades and occupies Hungary; most Hungarian Jews, who had largely been able to avoid persecution under strongman Miklós Horthy, are deported to Nazi concentration camps. 1945 Budapest is liberated by the Soviet army in April, a month before full victory in Europe, with three-quarters of its buildings and all of its bridges in ruins. 1949 The communists, now in complete control, announce the formation of the 'People's Republic of Hungary'; Stalinist show trials of 'Titoists' and other 'enemies of the people' begin. 1956 Budapest is in flames after riots in October; Hungary briefly withdraws from the Warsaw Pact and proclaims its neutrality but the status quo is restored and János Kádár installed as leader. 1958 Imre Nagy and others are executed by the communist regime for their role in the uprising and buried in unmarked graves in Budapest's New Municipal Cemetery. 1963 Amnesty is extended to those involved in the 1956 Uprising by the communist government after a UN resolution condemning the suppression of the rebellion is struck from the agenda. 1968 Plans for a liberalised economy are introduced in an attempt to overcome the inefficiencies of central planning but are rejected as too extreme by conservatives. 1978 The Crown of St Stephen is returned to Hungary from the USA, where it had been held at Fort Knox in Kentucky for safekeeping since the end of WWII. 1988 János Kádár is forced to retire in May after more than three decades in power; he dies and is buried in Budapest's Kerepesi Cemetery the following year. 1989 The electrified fence separating Hungary and Austria is removed in July; communist power is relinquished; the Republic of Hungary
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4, 3709, 346, 1473, 15125, 15, 73, 3, 187, 4, 3709, 346, 12352, 64, 34467, 15, 73, 3, 187, 187, 565, 5007, 30936, 9, 1030, 1018, 11, 26023, 64, 9834, 5349, 535, 187, 565, 187, 7265, 9, 540, 46090, 13, 1018, 11, 39989, 5456, 2387, 187, 92, 187, 186, 5397, 1874, 187, 186, 16065, 9, 46090, 2387, 551, 187, 186, 5045 ]	to the tune of taylor swift (complete with dance moves) Chef Crawford prepared pasta for us in several ways. First we enjoyed a duo of rotini with marinara sauce and spaghetti with basil pesto. Sooo good! I finished every last bite, which shows that healthy eating doesn't have to be boring - Catelli's Ancient Grains pasta tastes great and delivers a ton of nutritional benefits. In fact, I liked the taste and texture better than regular whole wheat pasta. This Ancient Grains pasta will be my new go-to choice for delicious and healthy dinners (or lunches... or any other time I need some pasta!) After Chef Crawford's cooking demo we moved into smaller groups to try our hands at preparing 'Chilled Noodle Salad with Ginger Wasabi Dressing' using Ancient Grains Spaghettini. It had a ton of fresh, crunchy vegetables and the noodles held up really well to the zippy dressing. I'll definitely be making this one again - in fact I'm already imagining enjoying this tasty salad by the bowlful for summer evening dinners on the patio. Chilled Noodle Salad with Ginger Wasabi Dressing 1 pkg Catelli Ancient Grains Spaghettini 2 cups snowpeas, blanced in hot water, then thinly sliced on a diagonal 1 cup shelled edamame beans 1 cup red pepper, cut into matchsticks 1 small long english cucumber, seeded and thinly sliced 2 cups napa cabbage, finely shredded 3 green onions, thinly sliced 1/4 cup seasoned rice vinegar 3 tbsp canola oil 2 tbsp soy sauce 1 tsp lemon zest 2 tbsp lemon juice 2 tsp brown sugar 2 tsp sesame oil 2 tsp fresh grated ginger wasabi to taste 1 ripe avocado, sliced 1/4 cup fresh cilantro leaves 2 tbsp black sesame seeds Prepare the pasta according to the directions on the package. Rinse with cold water and drain well. Toss with a few tbsp of canola oil and set aside. While the pasta is cooking, prepare all the vegetables. Add the rice vinegar, canola oil, soy sauce, lemon zest & juice, brown sugar, sesame oil, ginger and wasabi into a jar with a lid (or something similar). Shake everything together until mixed well. (According to Chef Crawford shaking is better than mixing, especially if you're dancing at the same time). Toss the salad dressing with all of the prepared vegetables. Put into a large serving bowl and top with avocado slices, cilantro leaves and black sesame seeds. The event was held at Get Cooking. Their kitchen is beautiful! All of the staff were so friendly and helpful. Get Cooking prepared several appetizers for us and everything was super tasty. I loved the chickpea pancake with kale on top and the beet macaron with hummus filling. This was the first time I had heard of Get Cooking, but I'd love to go back and take one of their cooking classes some time. Messy Little Cook Test Hi, I'm Courtenay. I truly am the 'Messy Little Cook' - there's sure to be a mountain of dirty dishes and flour all over the place whenever I'm playing in the kitchen. I also love writing about restaurants, other foodie stuff and travel (when I get the chance). Looking for something? To Follow me on Pinterest or Instagram click on the icons below: Two little ballerinas 💕 #mayowskifamily Walking my big girl to the school bus ☀️#beautifulfallmorning #mayowskifamily Camping in Banff for the long weekend 💕 We played, paddleboarded, hiked to the tea house, ate ice cream, roasted marshmallows and had a great time together as a family. #mayowskifamilycamping #campingwithkids #banffnationalpark #getoutside #mayowskifamily In that last video of Hannah, the first time (off camera) she told me she loved s'mores more than me 🥺 she's working on being funny - and it actually is pretty funny Huge THANKS to @bagelbar.yeg and @derosebrosmeats for the bagels, cream cheese, sandwiches and tots!! I won their giveaway earlier this summer and picked it up today to share with my team at work 🤤🤤🤤 everything was thoroughly enjoyed 👍 Happy Grade 1 Hannah! #firstdayofschool #yegkids #mayowskifamily The last camping adventure of the year has begun. Tonight we're hanging out under the romantic lights of...the Bass Pro shop parking lot and listening to the soothing sounds of QE2 traffic 🙃 #parkinglotcamping #mayowskifamily Today is our 10th anniversary ♥️ So I'm sharing 10 of my memories from our wedding day. A walk down memory lane, August 21, 2009 1) So unbelievably happy to married to this guy 😍 2) Getting ready with our moms, my sister and future sister-in-law. It felt like the greatest game of dress-up ever. I loved my wedding dress and veil 3) Walking down the aisle with my parents. I wish I could go back in time to slow this moment down. I could feel their love, support and pride 4) Seeing Trevor waiting for me at the end of the aisle. My heart was filled with butterflies, but I couldn't wait to be there with him 5) Crying while saying my vows. I knew I would cry - I'm surprised I actually got through it 6) You may kiss the bride! I made Trev practice "the kiss" before the wedding 😘 7) So greatful for our family and friends who celebrated with us 8) We slipped into the Winspear auditorium for a few photos before the reception. It felt glamorous and special to stand on the stage under the lights. While Kelsy was taking our photos the man tuning the organ was also snapping our pic 9) I surprised Trevor with an extra wedding cake (chocolate mint flavor) to apologize for my bridezilla moment when I told him that was not an acceptable wedding cake flavor 😂 everyone loved the chocolate mint cake 10) Hanging out in downtown Edmonton taking pictures with my favorite people. Everyone else was good at the sexy/serious face...me, not so much, haha. I just couldn't hide my huge smile. Happy anniversary Trevor, I love you forever ♥️ 📸@kelsynielson @edmontonfamilyphotographer #tenthanniversary #weddingmemories #yegweddings #husbandandwife #10yearslater #mayowskifamily Trev made an excellent dinner of mussels in wine with homemade mayo and oven fries. The kids devoured everything. My feeding-therapist heart was glowing with pride as the kids gobbled down the mussels and asked for more (even though this kind of thing doesn't happen all the time) #adventurouseaters #dadmadedinner #foodiekids We're really good at family pictures 🤦#mayowskifamily Checking out the playground Trev used to play on when he was a kid, feeding Rose the Squirrel (as named by the kids) and one last popsicle before the long drive home #mayowskifamily More beach and s'mores please! #campingincanada #mayowskifamily Nate was so excited to take me for a ride on the board, he was shouting take my picture, it's my first paddle! Once the kiddos were asleep Trev and I got to enjoy a sunset walk along the lake #mayowskifamily Family camping trip to Kimball Lake. The mornings were cool, but the afternoons were warm enough to enjoy the beautiful beach. My nature kids loved it #mayowskifamily/*************************************************************** * * Copyright (C) 1990-2007, Condor Team, Computer Sciences Department, * University of Wisconsin-Madison, WI. * * Licensed under the Apache License, Version 2.0 (the "License"); you * may not use this file except in compliance with the License. You may * obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * **************************************************************/ #include "condor_common.h" #include "condor_config.h" #include "condor_attributes.h" #include "condor_commands.h" #include "daemon.h" #include "dc_starter.h" int sendCmd( const char starter_addr ); int main( int argc, char* argv[] ) { config(); switch( argc ) { case
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1077, 3782, 13027, 1957, 330, 18, 14, 36, 21, 14, 18573, 13, 330, 18, 14, 36, 21, 14, 1278, 9356, 13, 330, 18, 14, 36, 21, 14, 18573, 19741, 13, 1073, 8422, 36, 18, 14, 36, 21, 14, 18573, 10, 19741, 390, 12992, 21, 14, 18573, 394, 900, 13, 1016, 273, 534, 310, 33323, 18528, 407, 16504, 460, 390, 42488, 13, 390, 1957, 29901, 13, 4188, 9356, 390, 29901, 394, 900, 13, 1016, 273, 534, 310, 33323, 18528, 407, 16504, 460, 13, 42488, 13, 27726, 460, 13, 33415, 13, 2645, 4692, 13, 9758, 13, 10258, 9356, 13, 492, 35536, 263, 37109, 390, 492, 35536, 263, 37793, 9356, 15, 187, 51, 23, 285, 416, 24, 10939, 273, 581, 1529, 1077, 3782, 13027, 1957, 9946, 13, 390, 1957, 330, 18, 14, 36, 21, 14, 18573, 13, 330, 20, 14, 36, 23, 14, 12642, 80, 18573, 13, 330, 18, 14, 36, 21, 14, 1278, 9356, 13, 330, 20, 14, 36, 21, 14, 1278, 257, 1190, 390, 330, 18, 14, 36, 21, 14, 1278, 9356, 14, 36, 19, 14, 36, 21, 14, 18573, 13, 1016, 273, 534, 310, 33323, 18528, 407, 16504, 460, 390, 42488, 13, 390, 1957, 29901, 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37793, 9356, 13, 33415, 390, 2645, 4692, 15, 187, 51, 1047, 1077, 3782, 13027, 6125, 9946, 390, 330, 18, 14, 36, 21, 14, 18573, 13, 390, 187, 51, 1012, 285, 416, 1047, 2366, 1077, 3782, 13027, 1957, 330, 21, 14, 36, 23, 14, 1278, 20625, 74, 1190, 15, 187, 51, 1010, 285, 416, 1036, 403, 8931, 390, 1027, 285, 1077, 3782, 13027, 1957, 9758, 390, 30097, 13, 390, 187, 51, 1010, 285, 416, 1036, 2366, 1077, 3782, 13027, 1957, 247, 330, 19, 14, 36, 20, 14, 1278, 20625, 74, 1190, 9329, 534, 310, 33323, 18528, 407, 9758, 13, 30097, 13, 295, 14, 38652, 13, 14928, 14, 38652, 13, 295, 14, 37476, 13, 14928, 14, 37476, 13, 4706, 14, 37476, 390, 24566, 14, 37476, 13, 390, 407, 29901, 534, 310, 33323, 18528, 407, 16504, 460, 13, 42488, 13, 10258, 9356, 13, 492, 35536, 263, 37109, 13, 492, 35536, 263, 37793, 9356, 13, 33415, 390, 2645, 4692, 15, 187, 510, 1840, 13012, 14308, 273, 26875, 390, 33954, 13, 275, 2087, 390, 835, 9013, 13794, 452, 644, 1677, 13, 476, 320, 5678, 342, 1016, 643, 347, 6799, 13, 326, 310, 281, 1333, 13553, 875, 253, 9056, 13794, 285, 9013, 13794, 403, 671, 1896, 15, 1583, 4647, 281, 253, 990, 3580, 285, 13, 7370, 4087, 13, 281, 253, 31744, 285, 43163, 15, 187, 14868, 13004, 2556, 281, 253, 3688, 403, 253, 7006, 273, 253, 7212, 313, 42, 10, 275, 534, 247, 5019, 273, 253, 30460, 5393, 1840, 347, 1146, 9013, 313, 11499, 254, 494, 10, 310, 1246, 15, 187, 7834, 21883, 9013, 2556, 281, 253, 3688, 403, 253, 7006, 273, 253, 7212, 313, 42, 10, 275, 534, 247, 5019, 273, 253, 30460, 5393, 1840, 347, 1146, 3782, 9013, 310, 1246, 15, 187, 17534, 3782, 9013, 2556, 281, 253, 3688, 403, 253, 7006, 273, 253, 7212, 313, 42, 10, 275, 534, 247, 5019, 273, 253, 30460, 5393, 1840, 347, 1146, 1077, 3782, 9013, 310, 1246, 15, 187, 52, 24668, 390, 45833, 34736, 26875, 13, 824, 347, 17519, 390, 355, 3612, 1190, 13, 671, 275, 4602, 342, 50116, 10917, 13, 824, 347, 13, 323, 1650, 13, 275, 9348, 9356, 13, 476, 320, 275, 1016, 1083, 4951, 14, 10050, 390, 36690, 347, 2080, 347, 436, 310, 1896, 15, 187, 16956, 595, 18528, 26875, 476, 320, 1114, 375, 538, 23572, 390, 23567, 538, 23572, 13, 352, 1146, 1896, 323, 253, 10829, 44385, 275, 2709, 35225, 281, 320, 8931, 390, 1027, 15, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 18, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 19, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 18, 14, 20, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 22, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 2042, 13, 275, 8956, 342, 1232, 313, 35, 582, 30097, 473, 14, 15830, 19, 13, 23, 14, 69, 40780, 80, 14, 21, 14, 13006, 4587, 22451, 28152, 12977, 19304, 47560, 310, 908, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 36, 582, 30097, 374, 14, 15830, 19, 14, 19700, 80, 14, 23, 14, 47257, 14, 21, 14, 13006, 4587, 22451, 12977, 21, 8422, 21, 14, 20912, 9356, 4587, 24865, 1190, 961, 17140, 80, 14, 21, 14, 13006, 14, 20, 14, 46652, 14, 1208, 5034, 310, 908, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 323, 1650, 13, 275, 8956, 342, 1232, 313, 38, 582, 10410, 27713, 4006, 1190, 374, 14, 15830, 19, 13, 21, 14, 69, 40780, 80, 14, 23, 14, 13006, 4587, 22451, 62, 23792, 1751, 285, 48886, 403, 908, 347, 4983, 7006, 13, 253, 2282, 273, 253, 9758, 4587, 22451, 62, 23792, 1751, 285, 32788, 46648, 15320, 403, 908, 347, 4983, 7006, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 40, 89, 26047, 18, 582, 495, 14, 15830, 19, 13, 23, 14, 69, 40780, 80, 14, 21, 14, 13006, 4587, 22451, 12977, 22, 13, 22, 14, 34342, 14, 4789, 83, 1102, 13196, 14, 19, 13, 21, 14, 69, 6035, 285, 268, 2401, 24592, 21437, 403, 908, 347, 4983, 15991, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 40, 10, 313, 15417, 34833, 19, 582, 495, 14, 15830, 19, 13, 21, 14, 69, 40780, 80, 14, 23, 14, 13006, 4587, 22451, 12977, 21, 14, 19304, 14, 22, 14, 22451, 14, 89, 26047, 26, 3079, 14, 5168, 8724, 71, 22017, 14, 19, 14, 531, 285, 44963, 44927, 504, 403, 908, 347, 4983, 7006, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 187, 2042, 13, 275, 8956, 342, 1232, 313, 41, 582, 854, 14, 15830, 19, 13, 21, 14, 69, 40780, 80, 14, 23, 14, 13006, 4587, 22451, 12977, 18, 13, 23, 14, 69, 13306, 357, 2576, 45679, 8422, 21, 13, 20, 13, 520, 13, 23, 4587, 4160, 1351, 14, 24, 13, 26, 14, 69, 6035, 285, 5105, 9356, 4040, 10410, 45193, 366, 403, 908, 347, 4983, 7006, 13, 253, 2282, 273, 253, 1232, 2556, 281, 253, 3688, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 42, 582, 12955, 34833, 18, 13, 495, 14, 15830, 19, 13, 23, 14, 69, 40780, 80, 14, 21, 14, 13006, 4587, 22451, 12977, 21, 14, 19304, 14, 23, 8422, 20, 14, 42609, 1190, 4587, 4789, 29037, 285, 9758, 10410, 16142, 837, 900, 630, 366, 403, 908, 347, 4983, 4753, 13, 253, 2282, 273, 253, 4884, 476, 320, 6607, 347, 3637, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 44, 582, 12955, 34833, 19, 13, 608, 14, 15830, 19, 14, 19700, 80, 14, 23, 14, 47257, 14, 21, 14, 13006, 4587, 22451, 12977, 23, 14, 19304, 14, 19, 8422, 21, 14, 19700, 412, 19692, 4587, 394, 13306, 249, 14, 21, 14, 531, 13, 6315, 557, 335, 545, 504, 285, 9758, 25723, 504, 403, 908, 187, 2042, 13, 275, 8956, 342, 1232, 313, 43, 582, 374, 14, 15830, 19, 13, 21, 14, 69, 40780, 80, 14, 23, 14, 13006, 4587, 22451, 12977, 18, 13, 22, 14, 4528, 17428, 14, 4789, 83, 1102, 13196, 14, 19, 13, 21, 14, 69, 6035, 285, 10258, 6597, 335, 35396, 1190, 21437, 403, 908, 347, 4983, 4753, 13, 253, 2282, 273, 253, 4884, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 44, 582, 374, 14, 15830, 19, 13, 23, 14, 69, 40780, 80, 14, 21, 14, 13006, 4587, 22451, 12977, 21, 14, 19304, 14, 22, 14, 13006, 14, 23, 8422, 19, 14, 42609, 1190, 4587, 4789, 29037, 285, 374, 13, 19, 13, 19, 14, 1206, 35536, 12892, 4040, 10258, 266, 678, 900, 19700, 25982, 33912, 403, 908, 347, 4983, 4753, 13, 253, 2282, 273, 253, 4884, 476, 320, 6607, 407, 253, 1563, 5150, 27, 209, 187, 2042, 13, 275, 8956, 342, 1232, 313, 45, 582, 495, 14, 15830, 19, 13, 21, 14, 69, 40780, 80, 14, 23, 14, 13006 ]	2x80x83or represents phenoxy-C1-C4-alkyl which is optionally substituted by fluorine, chlorine, methyl or ethyl, or xe2x80x83represents pyridyloxy-C1-C4-alkyl, pyrimidyloxy-C1-C4-alkyl or thiazolyloxy-C1-C4-alkyl, each of which is optionally substituted by fluorine, chlorine, amino, methyl or ethyl. R2 very particularly preferably represents C1-C4-alkyl, C2-C14-alkenyl, C1-C4-alkoxy-C2-C6-alkyl or poly-C1-C4-alkoxy-C2-C6-alkyl, each of which is optionally substituted by fluorine or chlorine, xe2x80x83or represents C3-C6-cycloalkyl which is optionally substituted by fluorine, chlorine, methyl, ethyl, n-propyl, iso-propyl or methoxy, xe2x80x83or represents phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, cyano, nitro, methyl, ethyl, n-propyl, i-propyl, methoxy, ethoxy, trifluoromethyl or trifluoromethoxy, R3 very particularly preferably represents methyl, ethyl, propyl or isopropyl, each of which is optionally substituted by fluorine or chlorine, or represents phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, iso-propyl, tert-butyl, methoxy, ethoxy, isopropoxy, tert-butoxy, trifluoromethyl, trifluoromethoxy, cyano or nitro. R4 and R5 independently of one another very particularly preferably represent C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylamino, di-(C1-C4-alkyl)amino or CC4-alkylthio, each of which is optionally substituted by fluorine or chlorine, or represent phenyl, phenoxy or phenylthio, each of which is optionally substituted by fluorine, chlorine, bromine, nitro, cyano, methyl, methoxy, trifluoromethyl or trifluoromethoxy. R6 and R7 independently of one another very particularly preferably represent hydrogen, or represent C1-C4-alkyl, C3-C6-cycloalkyl, C1-C4-alkoxy, C3-C4-alkenyl or C1-C4-alkoxy-C2-C4-alkyl, each of which is optionally substituted by fluorine or chlorine, or represent phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl, or together represent a C5-C6-alkylene radical which is optionally substituted by methyl or ethyl and in which one methylene group is optionally replaced by oxygen or sulphur. R13 very particularly preferably represents hydrogen, or represents C1-C4-alkyl or C1-C4-alkoxy, each of which is optionally substituted by fluorine or chlorine, or represents C3-C6-cycloalkyl, or represents phenyl, phenyl-C1-C2-alkyl or benzyloxy, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, iso-propyl, tert-butyl, methoxy, ethoxy, iso-propoxy, tert-butoxy, trifluoromethyl, trifluoromethoxy, nitro or cyano. R14 very particularly preferably represents hydrogen or C1-C4-alkyl, or R13 and R14 together very particularly preferably represent C4-C6-alkanediyl. R15 and R16 are identical or different and very particularly preferably represent methyl or ethyl, or R15 and R16 together very particularly preferably represent a C2-C3-alkanediyl radical which is optionally substituted by methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl or tert-butyl, or by phenyl which is optionally substituted by fluorine, chlorine, methoxy, trifluoromethyl, trifluoromethoxy, nitro or cyano. The abovementioned definitions of radicals or illustrations, in general or where preferred ranges have been given, can be combined with each other as desired, that is to say combinations between the respective ranges and preferred ranges are also possible. They apply to the end products and, analogously, to the precursors and intermediates. Preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being preferred (preferable) is present. Particularly preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being particularly preferred is present. Very particularly preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being very particularly preferred is present. Saturated or unsaturated hydrocarbon radicals, such as alkyl or alkenyl, also in connection with hetero atoms, such as, for example, in alkoxy, can be in each case straight-chain or branched as far as this is possible. Optionally substituted radicals can be monosubstituted or polysubstituted, it being possible for the substituents in multiple substitutions to be identical or different. Individual compounds of the formula (I-1-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (I-2-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (1-3-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (I-5-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: If, in accordance with process (B), ethyl O-[(2,6-dichloro-4-methyl)-phenylacetyl]-hydroxyacetate is used, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (C), ethyl 2-[(2-chloro-6-fluoro-4-methyl)-phenyl]-4-(4-methoxy)-benzylmercapto-4-methyl-3-oxo-valerate is used, the course of the process according to the invention can be represented by the following equation: If, for example, in accordance with process (E), chlorocarbonyl 2-[(2,4-dichloro-6-methyl)-phenyl] ketene and acetone are used as starting compounds, the course of the methyl)-phenyl] ketene and thiobenzamide are used as starting compounds, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (Gxcex1), 3-[(2,6-dichloro-4-methyl)-phenyl]-5,5-dimethyl-pyrrolidine-2,4-dione and pivaloyl chloride are used as starting substances, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (G) (variant xcex2), 3-[(2,4-dichloro-6-methyl)-phenyl]-4-hydroxy-5-phenyl-xcex943-dihydrofuran-2-one and acetic anhydride are used as starting compounds, the course of the process according to the invention can be represented by If, in accordance with process (H), 8-[(2,4-dichloro-6-methyl)-phenyl]-1,6-diazabicyclo-(4,3,01,6)-nonane-7,9-dione and ethoxyethyl chloroformate are used as starting compounds, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (I), variant xcex1, 3-[(2,6-dichloro-4-methyl)-phenyl]-4-hydroxy-6-(3-pyridyl)-pyrone and methyl chloromonothioformate are used as starting materials, the course of the reaction can be represented as follows: If, in accordance with process (K), variant xcex2, 5-[(2-chloro-6-fluoro-4-methyl)-phenyl]-6-hydroxy-2-(4-chlorophenyl)-thiazin-4-one, carbon disulphide and methyl iodide are used If, in accordance with process (J), 2-[(2,4-dichloro-6-methyl)-phenyl]-1,5-dimethylene-pyrrolidine-2,4-dione and methanesulphonyl chloride are used as starting materials, the course of the reaction can be represented by the following equation: If, in accordance with process (K), 2-[(2,6-dichloro-4-methyl)-phenyl]-4-hydroxy-5-methyl-6-(2-pyridyl)-pyrone and 2,2,2-trifluoroethyl methanethiochlorophosphonate are used as starting materials, the course of the reaction can be represented by the following equation: If, in accordance with process (L), 3-[(2,4-dichloro-6-methyl
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58, 393, 6040, 393, 68, 45, 64, 59, 1352, 3954, 347, 275, 253, 4737, 273, 11506, 905, 8560, 27, 20188, 2582, 5251, 2582, 18, 5290, 1580, 253, 669, 3442, 269, 9, 17, 13, 17, 1009, 26019, 253, 4315, 13905, 273, 370, 58, 1352, 33062, 969, 6935, 6681, 905, 5616, 27, 491, 2582, 11097, 2582, 1940, 261, 297, 696, 285, 905, 5616, 27, 22202, 2582, 936, 2582, 1940, 261, 6213, 696, 285, 970, 253, 4038, 273, 253, 12314, 2792, 359, 4044, 326, 512, 273, 253, 2792, 273, 253, 830, 669, 1274, 9, 59, 64, 18, 1337, 5589, 13, 59, 578, 76, 14, 18, 2023, 17, 1337, 5589, 13, 17, 61, 918, 1009, 403, 4229, 407, 370, 71, 1352, 187, 187, 688, 1798, 13, 604, 253, 11627, 273, 370, 57, 5, 403, 23352, 3907, 13, 840, 253, 11627, 273, 370, 58, 5, 403, 23352, 3907, 285, 352, 8018, 326, 253, 4309, 26019, 669, 71, 35, 64, 69, 9, 79, 3822, 2896, 253, 1959, 2715, 273, 16619, 266, 457, 84, 10012, 313, 2887, 1008, 11773, 53, 1036, 1092, 1008, 49, 11192, 14573, 740, 62, 285, 1008, 20, 52, 2498, 844, 7525, 326, 370, 71, 5, 310, 253, 6489, 15, 187, 187, 510, 1840, 18057, 310, 253, 1327, 42253, 7370, 273, 247, 1750, 432, 1008, 51, 438, 249, 62, 326, 253, 4229, 2792, 273, 247, 33592, 3711, 370, 71, 393, 13777, 393, 35, 64, 69, 393, 936, 393, 35, 64, 69, 1366 ]	$ the space of all homogeneous linear polynomials on $d$ variables of degree one satisfied by the coordinates of $X$. Applying a unitary we can always assume that $\cL_X$ is spanned by $z_k,\ldots,z_d$. In [@3S] Salomon, Shalit and the author have defined the notion of a matrix span of a set of points $\cS \subset \M_d$. Recall that the matrix span of a set $\cS$ is defined via $${\operatorname{mat-span}}(\cS)(n) = {\operatorname{Span}}\left\{ \left(I_d \otimes T \right)(X) \mid X \in \cS(n),\, T \in \cL(M_n) \right\}.$$ Here $\cL(M_n)$ stands for the linear operators on $M_n(\C)$ and for each $T \in \cL(M_n)$ we have $\left( I_d \otimes T\right)(X) = \left(T(X_1), \ldots, T(X_d)\right)$. \[lem:mat-span\] If $\cS = \{X\}$ for $X \in \M_d(n)$, then ${\operatorname{mat-span}}(\cS)(n)$ is precisely the set of points $Z \in M_d(n)$, such that $\cL_X \subset \cL_Z$. First, let us assume that $\cL_X = \{0\}$, i.e, the coordinates of $X$ are linearly independent. Then applying linear transformations $T \in \cL(M_n)$ coordinate-wise, we can get any point in $\M_d(n)$ and thus we are done. Now assume that $X = \left(X_1,\ldots,X_{k-1},0,\ldots,0 \right)$, with $X_1,\ldots,X_{k-1}$ linearly independent. As in the previous case we can get by applying linear transformations coordinate-wise any point of the form $Z = \left(Z_1,\ldots,Z_{k-1},0,\ldots,0\right)$. In particular, every such point satisfies $\cL_X \subset \cL_Z$. Applying a linear transformation on the coordinates just changes bases in the spaces of linear polynomials and thus the above statement is true for any $X$. To prove the converse inclusion observe that if $Z \in {\operatorname{mat-span}}(\cS)(n)$, then there exist a linear transformation $T \in \cL(M_n)$, such that $$Z = \left( I_d \otimes T \right)(X) = \left(T(X_1),\ldots,T(X_d)\right).$$ Hence if $p = \sum_{j=1}^d \alpha_j z_j \in \cL_X$, then by linearity $p(Z) = T(p(X)) = 0$ and thus $p \in \cL_Z$. \[prop:fixed\_level\_1\] If $f$ is an nc self-map of $\fB_d$, such that $f$ fixes the subspace of points of the form $(z_1,\ldots,z_{k-1},0,\ldots,0)$ in $\fB_d(1)$, for $k > 2$, then $f$ fixes all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$. By Lemma \[lem:one-dim\_fixed\] we know that the points $(Z_1,0,\ldots,0)$, $(0,\ldots,0,Z_{k-1},0,\ldots,0)$ are fixed by $f$. Now [@3S Lemma 8.1] implies that $\Delta f(0,0)$ fixes the matrix span of these points and thus fixes all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$. Consider the $n$-th level $\fB_d(n)$. Let $Z = (Z_1,\ldots,Z_{k-1},0,\ldots,0)$ be a point such that $Z/\\|Z\\|$ is coisometric. As was mentioned there is a unique geodesic passing between $0$ and $Z$ and it is just the disc through the two points. Additionally, the above argument shows that $\Delta f(0,0)(Z) = Z$ and it is the derivative of $f$ at the origin on level $n$. Applying Lemma \[lem:der\_fix\_coisom\] we get that the geodesic $w \mapsto w Z$ is fixed by $f$. By Lemma \[lem:similar\_to\_coisometry\] every generic point of the form $(X_1,\ldots,X_{k-1},0,\ldots,0)$ is similar to such a $Z$ we conclude that every generic point of this form is fixed. Since $k > 2$ the generic points are dense in the set of all points of this form and thus the entire set is fixed. This proposition combined with Lemma \[lem:one-dim\_fixed\] gives us the following corollary. \[cor:fixed\_subspace\] Let $f \colon \fB_d \to \fB_d$ be an nc-map, such that $f(0) = 0$. Let $V(1)$ be the fixed point set of $f$ on the first level. Set $V(n) \subset \fB_d(n)$ the subspace of matrices, such that their coordinates satisfy the linear relations of $V(1)$ and $V = \sqcup_{n = 1}^{\infty} V(n)$. Then $f$ fixes $V$. \[prop:fixes\_lin\_independent\_point\] Let $f \colon \fB_d \to \fB_d$ be an nc-map, such that $f(0) = 0$. If there exists a generic point $X \in \fB_d(n)$, such that $f(X) = X$, then $f(Z) = Z$, for every $Z \in \fB_d$, such that $\cL_X \subset \cL_Z$. In particular, if the coordinates of $X$ are linearly independent, i.e., $\cL_X = \{0\}$, then $f$ is the identity map. Since $f$ is nc and it fixes $X$, it is forced to fix the similarity orbit of $X$ in the ball, namely $\left(\GL_n(\C) \cdot X \right) \cap \fB_d(n)$. By Lemma \[lem:similar\_to\_coisometry\] the similarity orbit contains a point $Y$, such that $Y/\\|Y\\|$ is a coisometry. Note that $Y$ is also generic and $\cL_Y = \cL_X$, since the action of $\GL_n(\C)$ is linear. By [@Vig84 Corollary 4.2] we have that there exists a complex geodesic consisting of fixed points of $f$ that connects $0$ to $Y$. Since $Y/\\|Y\\|$ is a coisometry and thus a complex extreme point on the boundary, this geodesic is necessarily $z \mapsto z Y/\\|Y\\|$. Thus, in particular, the derivative of $f$ at $0$ fixes this line as well. Since $f$ is an nc map, the derivative at $0$ is $\Delta f (0,0) \otimes I_{M_n}$ and it fixes the line $z Y$. By [@3S Lemma 8.1] we have that it must fix the intersection of the matrix span of $Y$ with the ball. As above we may assume that $Y = (Y_1,\ldots, Y_{k-1},0,\ldots,0)$, with $k > 2$ and $Y_1,\ldots, Y_{k-1}$ linearly independent. By Lemma \[lem:mat-span\] the matrix span of $Y$ on level $n$ is precisely the set of all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$, i.e., $\cL_Y \subset \cL_Z$. Now as in the proof of Proposition \[prop:fixed\_level\_1\], since the $\Delta f(0,0)$ fixes the matrix span of $Y$. Applying again Lemmas \[lem:der\_fix\_coisom\] and \[lem:similar\_to\_coisometry\] and using the density of the generic points we obtain that all of the points of the form $\left(Z_1,\ldots,Z_{k-1},0,\ldots,0\right)$ are fixed by $f$. In particular, if the coordinates of $X$ are linearly independent, then the coordinates of $Y$ are linearly independent and it implies that the derivative fixes $\fB_d(n)$. By the free version of Cartan’s theorem (see [@McT16], [@Popescu10] and [@3S]). We conclude that $f$ is the identity. The above lemma is the noncommutative analog of a claim from [@Rudin] that the fixed points of a holomorphic map $f \colon \B_d \to \B_d$,
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A: How should I approach both Director of Business Development and the Company Founder (we have a VERY flat hierarchy) to demand better transparency since the director's results affect my livelihood immensely? Find another job. Demand cash upfront. You've joined the company for a better work/life balance but the most likely you will be overwhelmed with various tasks and burnout just to get marginal gain to your current compensation which is already below market rate. Managers use vague language to postpone your salary increase. You're in position to think like shareholder - are you compensated in stocks or options? If you'll bring customers, how it will relate with your salary - is it specific agreement or just abstract saying? Looks contradicting: we have a VERY flat hierarchy) to demand better transparency A: I'm also new at responding, so please edit if I'm incorrectly doing this. Challenging your question here. First, my assumption: You said that management was saying your salary would go up if you directly brought in new clients, and then are saying you wish to support some new hire who's job it is to bring in new clients. Please correct if mistaken. I think its great that you wish to support this hire. That would definitely provide value and despite some odd phrasing, would match up with what you said is affecting your salary and your management should increase it. That said, I find the entire setup very suspicious. First, if you're a developer it is NOT your job to bring in new clients. Part of your job could easily be to provide a professional face when interacting with them, but you shouldn't be making sales calls and trying to bring up new business. At least, I'm assuming you aren't being paid to. However, that also doesn't mean you are entitled to know everything this new hire is doing to bring in business. Yes, you clearly have a small company, but that doesn't really matter. A marketing or sales department (whether 1 person or a whole team of 50) are their own separate entity and providing value to the company by finding new clients. I would certainly expect there to be some overlap, like if they want to market a particular phrase they would let the development team know to use specific wording, but I wouldn't expect them to seek your approval on their overall marketing strategy. To put it another way, why should you have total transparency into their job and ensuring they are 'finding new clients correctly?' If that was the case, whats to stop this Director of Business Development from demanding total transparency into YOUR work and how you're coding and interacting with clients? After all, your work results immensely impact her livelihood since if you can't provide whats stated to clients, then they'll take their business elsewhere. That sounded harsher than intended. Again, there is definite value in different teams working together to build off each other, and I encourage you to set that meeting anyways. I would just ask you instead talk about a way to share ideas / motifs/ themes to help build your company's 'brand' Let me see if I understand you correctly. You're saying the MS-8 is a "drop-in" replacement for the OEM amp, buy your interface harness and I'm done? So your harness provides all connections, including power, to the amp? If it's that simple, I gotta ask the price of the harness. I also have to ask since you appear to be a fan of staying with OEM speakers and just replacing the OEM amp, if you were to upgrade the OEM speakers, do you have any "drop-in" replacement speaker recommendations for the F25 X3? The difference is that for the F25 a center speaker input is added to the harness (F25 OEM amp is 7 channel vs the E90 OEM amp 6-channel). I do not recommend using the OEM amp 12V power source to drive the MS-8, only using a direct to battery connection for 12V. The OEM amp ground could be used for the MS-8 and it is provided at the harness. I do not have the F25 speaker measurements but I would assume that they are the standard 4" and 8" speakers, which in that case any 4" component set of less than 50mm deep would work. An 8" woofer of less than 65mm deep ("shallow" woofer) would also work (SWS-8, Jehnert XE200, Rainbow W200 X-Plain, for example). The SWS-8 is more a subwoofer than a midbass driver, the other two woofers are more of a midbass driver. Any of these woofers will require a more powerful aftermarket amplifier than the internal MS-8 amps, though.1. Introduction {#sec1} =============== Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic erosive arthritis. Inflammation in the synovium of joint and progressive damage of the bone and cartilage are the main pathological characteristics. Patients with RA mainly show joint pain, swelling, stiffness, or permanent destruction, and some of this severe damage can lead to disability and malformation or even systemic manifestation \[[@B1]\]. In the progress of RA, bone damage is an important cause of the patients\' dysfunction \[[@B2]\]. Thus, bone rebuilding is crucial in the recovery process. While in bone rebuilding, three pathways, including BMP2-Smads signal pathway, P38-MAPK pathway, and TNF-α/NF-κB pathway, play a vital role in osteoblast proliferation and differentiation and the injury-repairing process of bone and cartilage. Iguratimod (T-614) is a new small molecule compound with anti-inflammation and immune regulation functions which has a definite disease modifying effect in an animal RA model. Some researchers report that T-614\'s effect relies on suppressing several inflammatory factors and immunoglobulin \[[@B3]--[@B5]\]. T-614 can accelerate bone formation by inhibiting osteoclast activation and promoting osteoblast differentiation \[[@B6], [@B7]\]. However, the mechanism of T-614\'s effect on promoting osteoblast differentiation is still unclear. Studies show that T-614 increases the expression of Osterix (Osx), which is a zinc-finger transcription factor that was crucial in osteoblast differentiation. Meanwhile, two signal pathways may mediate this process, the recombinant human bone morphogenetic protein-2- (BMP2-) Smads signal pathway and the P38-MAPK pathway. BMP2 induces the expression of Osx, while there are several transcription factors upstream of Osx, such as Dlx-5 and Runx2. The MAPK pathway, mediated by P38, interacts with the BMP2-Smads pathway to improve Osx phosphorylation. In addition, TNF-α activates the NF-κB pathway to mediate inflammation. TNF/NF-κB pathway participates in osteoblast proliferation, the induction of osteoblast apoptosis, the inhibition of osteoblast differentiation, and the suppression of matrix proteins. In this study, we investigated the effect of T-614 on the osteogenesis process. We first tested the content of some osteogenesis markers, such as type I collagen (Col I), bone gla protein (BGP), the contents and activity of alkaline phosphatase (ALP), and calcium nodule formation in the mesenchymal stem cells to help to verify its effectiveness and function in promoting osteoblastic differentiation. Then, we aimed to assess T-614\'s effect on Dlx5 and P38, which are involved in two pathways of osteoblast differentiation. We also intended to investigate whether T-614 inhibits the TNF-α/NF-κB pathway. 2. Materials and Methods {#sec2} ======================== 2.1. Cell Culture {#sec2.1} ----------------- Mesenchymal stem cells (MSC) were isolated from murine bone marrow according to \[[@B8]\]. The cells were cultured in α-minimum essential medium (α-MEM; Invitrogen) supplemented with 10% fetal bovine serum (FBS; Equitech-Bio, Kerrville, TX) and bFGF (PeproTech) at 37°C in a humidified 5% CO2 incubator for several cycles. For each assay, MSCs were plated at 1 × 10^4^ cells/cm^2^, and various concentrations of T-614 were added with or without rhBMP-2 (Genetics Institute, Cambridge, MA). 2.2. ALP Content and Activity Detection {#sec2.2} --------------------------------------- MSCs were treated with rhBMP-2 and/or T-614 for 3 days. For ALP staining, the cells were fixed for 15 min with 3.7% formaldehyde at room temperature after washing with phosphate-buffered saline (PBS). Then, the cells were tested for ALP content by using an ALP staining kit (Nanjing Jiancheng Science and Technology Ltd., China) according to the manufacturer\'s instruction. To measure the ALP activity, the cells were washed twice with PBS and lysed in M-PER Mammalian Protein Extraction Reagent (Pierce, Rockford, IL) following the manufacturer\'s protocol. ALP activity was assayed using p-nitrophenylphosphate as a substrate by the Alkaline Phosphatase Test (Beyotime Biotechnology, China), and the protein content was measured using a bicinchoninic acid (BCA) protein assay kit (Pierce). ALP activity was calculated as the total activity units/the total protein concentration. 2.
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88, 262, 8266, 501, 3006, 268, 291, 980, 320, 284, 1405, 436, 1039, 964, 309, 1158, 326, 2006, 24669, 2827, 6475, 534, 310, 4270, 275, 858, 436, 9331, 187, 187, 688, 954, 6483, 383, 248, 36622, 436, 1039, 403, 1335, 3240, 1355, 1157, 387, 38462, 577, 14 ]	such a context, while both still continue to exist, function, and incorporate these age-old game elements in a meaningful and rational way.</p> <p>So there you go. I hope this was at least somewhat interesting and gives a taste of the familiar-but-different game world that is the Lost Lands.</p> <p>Greg</p> <p>P.S. If you haven't seen our latest Lost Lands product's Kickstarter, head over and check it out. Only 3 days to go!!</p> </div></div></div>Wed, 20 May 2015 16:43:39 +0000Greg A Vaughan3065 at https://www.froggodgames.comhttps://www.froggodgames.com/blog/telling-time-lost-lands#commentsNTRPG Con Game Registration is Uphttps://www.froggodgames.com/blog/ntrpg-con-game-registration <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Opened up last night. If you're going, hurry and sign up. They tend to fill up pretty fast.</p> </div></div></div>Wed, 15 Apr 2015 15:22:51 +0000Greg A Vaughan3042 at https://www.froggodgames.comhttps://www.froggodgames.com/blog/ntrpg-con-game-registration#commentsQ: GPO Policies are not being applied I'm an inexperienced AD/GPO admin trying to setup AD and use GPO to manage my kids laptop. I can get some user policies to apply but not computer policies. I've been spinning my wheels on this for over a day trying to figure out what I've done incorrectly preventing the full GPO to be applied to the laptop. I have provided some links to the GPRESULTS from the client laptop from an elevated cmd prompt as well as the report from the server on the GPO. The scope includes: Authenticated Users; The laptop computer, and the user group for my children One of the items set in the computer is dis-allowing the MS Store to be run, since you cant disable it in Win 10 Pro. Any help that can get this GPO working would be appreciated. https://pastebin.com/ygH1fiXa - Laptop GPRESULT https://pastebin.com/aeaqDCj3 - Server Results HTML - Copy & paste into a .htm file and view in a browser A: The issue I found yesterday was that the Computer was something I had added and not one that was put into the AD by joining it to the domain. Once I looked in the default computer OU I found what was created and used that to apply the GPO against. Pigeon Simulator: Town Bird Full iOS UniversalGames Fly in sky as a pigeon in Pigeon Simulator: Town Bird, wild dove sandbox! Welcome to one of the craziest animal games! Start your pigeon survival with our dove sandbox now. We like animals and strive to make our dove game best. Feed your flock of flying animals! This survival sandbox includes a map and a guide. Choose preferable mode of the sandbox - animals survival or quests. In our survival sandbox we offer you to learn craft of animals. Flying over town as a pigeon! Maintain your pigeon energy, fly over town, fight town and wild animals for survival. Craft to levelup your animals. Finish all quests - survival in the dove sandbox can be challenging, but funny in animal games. Learn to control your animals, lead a dove flock and more. You will meet a lot of animals species in the dove sandbox. To be a good town dove, or a wild pigeon - it is up to you. Enjoy fun of dove flying and sky nature. Craft your survival strategy. Town pigeon simulator is better than real wild animals! Live the life of animals in sandbox. Complete quests and do what doves do. Find a mate and breed a new town pigeon flock. Develop a survival strategy against wild and town animals. Levelup pigeon survival skills. Or find mates and start a flock. Town quest will open new survival skills. Yourtown pigeon can die in the sandbox - survival in the sandbox is not easy for animals. Flying like a pigeon is cool! Try Pigeon Simulator: Town Bird, be a pigeon and explore a big wild world!Very important : Please look at the coments on the end with many updates You may not know thatI am a avid book reader. Since I was young I was advanced by two yeas in the high schoolreading books on maths and chemistry of the university . by the time, as student of marketing and economics and the time I was learning English language I wasreadingAmerican books of marketing advertising and public relations and nearly little later with books on sellingwhich was my favoritereading . Since then upon the times I was adding in reading to some other specialized book areas such as related to radio and electronics , food and nutrition (a subjectthat I am still interested) computer techniques and programs with some interest in photopaint etc , and till nowwith some interest in baby caring , by reading magazines and books With the advent of book searching via the net I have collected some vey interesting booksthat some of them have already been printed ….. … until IO have boughtvery recentlya e-book reader that is supposed to stop printing ! Thise reader have been boughtfrom Plaisio , a chain storeof computer systemsand peripherals sold under the name turbo xE B600 , which is the brand name of mostly OEM products from supposedly China . This e reader usesthee ink technologya property patent from E ink companyusing micro bubbles to orientate in a thin film screen Its formatis very minimalusing 4+1 navigation buttons. At the right of this picutre there ar the buttons for font sizing And hereis a picture with the buttons on the left pane : First button goes for multimendia (smething i am not interested ), lanscape mode , exit mode(frm eradding mode ) and property mode (all adjustments including status bar etc ) The company claimsthata power chargecan support ca 7000 pagesor 30 hours of button operation … Its inside memory of ca 375MBcontainsthe ebook guide in the main directoryand n separate directoryca 60 books in pdf format , which are under the public domain . Several of them are Shakespeare’s Romeo nd Juliet , Homer’s Iliad and Odyssey, The art of war and many othersand only two Greek e-books . Navigationis quite simple - the reader is normally set to being switched always on . This is in contrast to most electronic appliances m becauseonce a page is applied , no electricityrequiredto keep the bubbles in their position ! In its off condition there is still a picture on the screen - A memory slot is also available using SD cards with memories up to 4 GB, The company Plaisio suggeststo insert the SD card with the power off … -Directory listing is of 3 modes , the basic can show only the titles , the second showsthe page name and a thumbnail of thefile and the third does it on two columns This is the analytical mode THis is the landscape file mode -Directory listing also supports direct access to the flash memory and files are shown mixed with a descriptive mark on the screen. ON the above picture is this shown on the exterme right of the dir listing There is ability to sortfiles by title , by author -Opening a fileis quite simple by just pressing the [enter ]in a file . In just 1-3 seconds most files have been loaded, depending on the file size . chm fileshowever require much more time , a 3.5 MB file requires about 40 secs! Once a file is opened , there is the abilityto change the font size with the buttons located in the right part of the reader . The correct page layout can be seen using the font off or size ‘1’ . The 2nd button from the leftcan turn the view into landscape . This happens also in the dir listing. Navigation is made with the 4 buttons . Left and right up and down work correctly for the directory listings but in reading mode left/up and right/down arrows do samework . Could expect a better solution Now , testing the reader I have found several interesting and peculiar things a follows: First e ink is not 100% white . See this picture : It seems eink is 60% gray leveled comapring to the pure white -Resizing fonts (numbers 2-7 )in pdfs with layouts , destroys the format in full separating the pictures at the ‘end’ of the virtual page . Landscaping retains the format in the font off option (1) butsplits the page into two parts upper and lower. Pageswith very small upper and lower marginssuffer from truncation ….(and that’s still debating in several cases ) For example this page wit font resizing pctures beasme this way . I think that Adibe erader which is built in did this fault In most casesthe fonts this way are still quite small , atleast 4-
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13, 330, 12303, 23, 13, 330, 12303, 21, 13, 285, 34956, 475, 67, 2992, 285, 476, 320, 5742, 33661, 970, 271, 8092, 1411, 330 ]	7 ml/g cell wet weight) in MP2 buffer (20 mM KP~i~ pH7.4, 0.6 M sorbitol, and 3 mg/g cell wet weight zymolyase 20T \[Seikagaku Corporation\]), and incubated with shaking for 1 h at 30°C for spheroplastation. Spheroplasts were harvested (3,000 g, 5 min, 4°C) and resuspended (13.4 ml/g cell wet weight) in homogenization buffer (10 mM Tris, pH 7.4, 0.6 M sorbitol, 1 mM EDTA, 1 mM PMSF, and 0.2% albumin bovine fraction V, fatty acid-free \[Serva\]). The following steps were performed on ice and centrifugations were performed at 4°C. After homogenizing the spheroplast suspension twice by 10--15 strokes of a Teflon plunger in a tight fitting homogenizer (Sartorius AG), the homogenate was centrifuged at 3,000 g for 5 min. Centrifugation was repeated once and mitochondria were then harvested by centrifugation at 17,000 g for 12 min. The pellet was resuspended in SH buffer (0.6 M sorbitol and 20 mM Hepes, pH 7.4) to a final concentration of 10 mg/ml. Mitochondria were snap-frozen in liquid nitrogen. Labeling of mitochondrial translation products in vivo ------------------------------------------------------ Cells were grown on minimal medium containing 2% galactose; 20 µg/ml arginine, methionine, threonine, and tyrosine; 30 µg/ml isoleucine; 50 µg/ml phenylalanine; 100 µg/ml valine; and 0.1% glucose ([@bib27]). A cell amount corresponding to an optical density (OD~595nm~) of 0.5 was collected, washed twice with minimal medium containing 2% galactose, and incubated at 30°C for 10 min in the same buffer supplemented with 0.15 mg/ml of all amino acids except methionine. After inhibiting cytosolic protein synthesis with 0.15 mg/ml cycloheximide, labeling of mitochondrial proteins was started by the addition of 6 µCi \[^35^S\]methionine. Pulse labeling was stopped after the indicated time points by addition of lysis buffer (1.85 M NaOH and 1.1 M β-mercapto-ethanol) containing 8 mM unlabeled methionine. After incubation for 10 min on ice, proteins were precipitated with 14% TCA. The stability of mitochondrial translation products was chased by stopping a 15-min labeling reaction by the addition of 8 mM of unlabeled methionine and taking samples after the indicated time points, which were lysed and TCA precipitated. Pellets were resolved in sample buffer, subjected to SDS-PAGE on 16:0.2% acrylamide/bisacrylamide gels, and analyzed by autoradiography and Western blotting. Fractionation of mitochondrial lysates -------------------------------------- Isolated mitochondria (300 µg) were lysed for 30 min on ice in lysis buffer containing 1% digitonin, 50 mM KCl, 1× complete protease inhibitor mix, 0.5 mM MgCl~2~, and 20 mM Hepes/KOH, pH 7.4. After a clarifying spin for 10 min at 25,000 g at 4°C, one half of the extract was precipitated with 12% TCA (100% total, T) and the rest was under-layered with 50 µl sucrose solution (1.2 M sucrose and 20 mM Hepes/KOH pH 7.4) and centrifuged for 105 min at 200,000 g in a TLA100 rotor (Beckman Coulter) at 4°C. The supernatant (S) was then collected and the ribosome-containing pellet (P) was resuspended in lysis buffer. Proteins of both fractions were precipitated with 12% TCA. The resulting pellets were dissolved in sample buffer, separated by SDS-PAGE, and analyzed by Western blotting. Analysis of bc~1~ complex assembly intermediates by 1D BN PAGE and 2D BN/SDS-PAGE --------------------------------------------------------------------------------- Isolated mitochondria (250 µg) were lysed in BN PAGE solubilization buffer (1% digitonin, 50 mM NaCl, 50 mM imidazole, pH 7, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. After a clarifying spin for 10 min at 25,000 g at 4°C, 25% of the lysate was taken as a total and the rest was loaded onto a linear (4--13%) BN polyacrylamide gradient gel. Electrophoresis was performed at 4°C. After one third of the run, the cathode buffer (50 mM Tricine, 7.5 mM imidazole, pH unadjusted, and 0.02% Coomasie G-250) was replaced by cathode buffer B/10 (50 mM Tricine and 7.5 mM imidazole, pH unadjusted; [@bib36]). For 1D BN PAGE analysis, the gel was stained with Coomassie brilliant blue. For the 2D SDS PAGE, gel slices from the first dimension were incubated in SDS running buffer containing 1% SDS, incubated for 20 min at 37°C, and placed vertically onto a SDS polyacrylamide gel. Separated protein complexes were analyzed by Western blotting. Immunodepletion of bc~1~ complex assembly intermediates ------------------------------------------------------- Isolated mitochondria (500 µg) were lysed in solubilization buffer (1% digitonin, 50 mM KCl, 50 mM imidazole, pH 7.4, 20 mM Hepes/KOH pH 7.4, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. The lysate was cleared at 25,000 g at 4°C for 10 min. Antibodies against Cbp3 were incubated with protein A--Sepharose beads and added to half of the mitochondrial lysate to immunoprecipitate Cbp3-containing complexes. The unbound material (NB) as well as the other half of the lysate (T) was subjected to 2D BN/SDS-PAGE. 25% of the samples were loaded directly on the SDS-PAGE and 75% of the samples were used for the 1D BN PAGE. 2D BN/SDS-PAGE was performed as described in the previous paragraph. The bound material after the immunoprecipitation (E) was eluted from the washed beads with SDS sample buffer and analyzed by SDS PAGE. Assembly kinetics of the bc~1~ complex -------------------------------------- To facilitate the assembly of newly synthesized cytochrome b, nuclear encoded proteins were accumulated in mitochondria before their isolation. To this end, mitochondrial translation was blocked by adding chloramphenicol to a final concentration of 4 mg/ml to yeast cultures 2 h before isolation of mitochondria. To label mitochondrial translation products, 800 µg of chloramphenicol pretreated mitochondria were incubated in 800 µl of in organello buffer (20 mM Hepes/KOH, pH 7.4, 15 mM potassium phosphate buffer, pH 7.4, 0.6 M sorbitol, 150 mM KCl, 12.66 mM MgSO~4~, 12.15 µg/ml amino acid mix \[without Tyr, Cys, or Met\], 66.66 µM cysteine, 12.13 µg/ml tyrosine, 7.5 mM phosphoenolpyruvate, 6 mM ATP, 0.75 mM GTP, 5 mM α-Ketoglutarate, and 10 µg/ml pyruvate kinase) at 30°C. After 2 min, mitochondrial translation was initiated by adding 80 µCi \[^35^S\]methionine and stopped 5 min later by adding nonradioactive methionine to a final concentration of 10 mM and puromycin to a final concentration of 80 µM. Assembly of newly synthesized mitochondrially encoded proteins was allowed to continue at 30°C. After a chase period of 0, 5, 15, or 30 min, 25% of the initial reaction was harvested and diluted 1:5 in ice-cold SH buffer (20 mM Hepes/KOH, pH 7.4, and 0.6 M sorbitol). Mitochondria were reisolated by centrifugation at 16,000 g at 4°C for 10 min and lysed in 50 µl of BN PAGE solubilization buffer (1% digitonin, 50 mM NaCl, 50 mM imidazole, pH 7, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. Lysates were clarified by centrifugation at 25,000 g for 10 min at 4°C and analyzed by 2D BN/SDS-PAGE. Miscellaneous ------------- Antibodies against Qcr7, Qcr8, and cytochrome b were obtained by immunizing rabbits with purified MBP-Qcr8, MBP-Qcr7, and peptide HGSSNPLGITGNLDRIPMHSYFI (amino acids 204--226 of cytochrome b coding sequence), respectively. The antibody against Arg8 was a gift from T. Fox (Cornell University). Signals from autoradiography or Western blotting were quantified with ImageJ software. Online supplemental material ---------------------------- Fig. S1 shows that cells carrying the cox2::COB cob::ARG8^m^ mitochondrial genome and lacking Cbp6 show the same phenotype as the corresponding Δcbp3 mutant. Fig. S2 shows that the 170 kD complex (intermediate I) is composed of Cbp3, Cbp6, Cbp4, and cytochrome b, and can be specifically depleted using an antibody against C
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22784, 7544, 2523, 273, 253, 9462, 16015, 32079, 8631, 247, 1885, 6289, 281, 347, 12762, 19, 89, 1438, 89, 26, 68, 30428, 47134, 7096, 19, 89, 1438, 89, 26, 69, 15, 28771, 318, 273, 253, 8144, 47134, 1885, 4419, 854, 281, 884, 23664, 17249, 273, 20131, 313, 531, 3301, 10, 281, 897 ]	of protest inspired activists across the country to join the fight to ensure that health care is a human right. And despite his deteriorating physical condition, Ady has always projected boundless joy and optimism into the world—even as the Capitol Police repeatedly took him into custody for expressing radical acts of love through nonviolent civil disobedience. Current Issue View our current issue Today, Ady is continuing to help build a powerful grassroots movement to win Medicare for All. (Senator Sanders is the author of the Medicare for All Act of 2019.) Health care is the leading issue dominating the Democratic presidential primary campaign. A veteran organizer at the Center for Popular Democracy, Ady’s ability to combine strategic organizing with tactical action is extraordinary. He has exemplified social justice work on a national level, showing a path beyond retrenchment that connects a vision of transformative justice with grassroots activism. For many of us, Ady Barkan represents the moral center of the political revolution. “Ady taught me that no matter how difficult the circumstances are, we can’t give up, because so many are counting on us,” said Linda Sarsour, cofounder of the Women’s March. “In Ady’s world, every breath is sacred and used to make this world just a little better than we found it ” Ady’s catalytic confrontation with Senator Jeff Flake made national headlines, but did not end with a viral video. Instead, it sparked what would become an urgent national discussion about health care. Ady’s story resonated across party identification and ideology, because everyone in America knows what it’s like to have a family member who is ill. Since that fateful exchange with Senator Flake on the airplane, Barkan went on to launch the Be A Hero PAC, which has raised $4.5 million to defeat Maine Senator Susan Collins in favor of a progressive candidate. As his physical condition deteriorates, Ady continues to participate in civil disobedience. He’s been arrested in the US Capitol building half a dozen times, and earlier this year, I was by his side when he testified in support of Medicare for All. I was awestruck by Ady’s bravery and ability to articulate a clear set of demands to lawmakers about an issue that affects all of us. I was also furious. Furious because our health care system has failed Ady, and so many people in America. “This moment calls on us all to become organizers,” Ady wrote last November. “To be heroes for our communities and future generations. To talk to our less political friends, neighbors, classmates, and co-workers, and to enlist them in this experiment we call American democracy.”Q: What is a momentary SPST Push Button Switch? I want to buy a switch (push button) where you press it to break the circuit and then press again to connect the circuit. I believe that this is what I'm looking for: However, I'm not entirely sure. I only want to use this for a basic circuit, and I mean really basic, so don't worry about anything there. A: SPST NO (Normally Open) Momentary switch is exactly what is inside a computer keyboard - press for on, let go for off. It sounds like you are looking for a Latching switch (works like a ballpoint pen) instead of Momentary. If you can only find one with more poles or features (DPDT) it'll do the job - just ignore the extra features. A brief look shows this from the same seller, I suspect he has others... This invention relates to a novel archway apparatus which is useful for building in wilderness areas, access roads, such as logging roads and secondary roads, over waterways such as streams and creeks, while causing little or not impact to sensitive wilderness environment. Typical road building processes in wilderness areas require the use of culverts in watershed areas to enable water to flow under the roadways built in those areas. Such culverts are typically constructed of corrugated steel pipe (CSP) or polyethylene-(HDPE) pipe. Installing these culverts requires that the creek or stream bed be disturbed or altered. This silt disruption upsets the natural habitat of the creek bed and causes harmful silt to move downstream. This can damage sensitive fish (including salmon) spawning beds. Once a culvert is installed, further problems arise. Water flowing through the confined interior of the culvert has higher than normal velocity. This occurs particularly during high water levels. Water flowing from the outlet (downstream) side of the culvert is turbulent and causes erosion in the creek bed area downstream of the culvert. Furthermore, since movement of the water through the culvert is restricted, water tends to back-up on the inlet (upstream) side of the culvert. This can cause erosion on the banks upstream of the culvert. The use of corrugated steel pipe (CSP) in building road culverts has been widespread. Such culverts rust over time, thereby causing an unnatural form of iron oxide pollution in the streams. CSP pipes are usually galvanized with zinc to reduce rusting. However, the zinc, in itself, as a natural process of erosion, releases a certain amount of zinc metal toxins to the waterways. This is in addition to the rust that is imposed on the environment after the zinc galvanization has corroded away. In many cases, old rusted CSP installations deteriorate structurally in strength to a point where they must be replaced. Replacement further disturbs the creek and stream beds. Over the years, numerous attempts have been made to avert such damage to creek and stream beds. Furthermore, there has been increasing pressure to preserve the environment and provide a managed balance between industrial and recreation use and conservation of natural resources. The Federal Department of Fisheries and Oceans (D.F.O.) and the British Columbia Ministry of Environment are in the process of changing their policy so as not to allow the replacement of CSP culverts with any product that disrupts the stream or creek beds. See a complete report of these requirements: Harper, D.J. and Quigley, J. T. 2000. No Net Loss of Fish Habitat: An Audit of Forest Road Crossings of Fish-Bearing Streams in British Columbia, 1996-1999. Canadian Technical Report of Fish and Aquatic Sciences 2319 (a 44 page report identified as CTR 2319). Alternatives such as suspended wooden trestle bridges, arches of rolled plate steel, and culverts of HDPE cut in half, and, of late, a material similar to CSP, have been used to overcome the typical problems associated with road building in environmentally sensitive areas. However, some of these alternative systems are costly and span distances are limited. Steel structures of any design suffer from the problem of rusting and thus contamination. In most cases, it is necessary to use heavy equipment for placement of the new heavy structures. This causes further disruption. The Federal Government of Canada has embarked on a program known as xe2x80x9cHarmful Alterations, Disruption or Destruction of Fish Habitatxe2x80x9d(H.A.D.D.), 1998. A search of the art reveals that different culvert attempts and designs have been published. A recent design is the use of xc2xexe2x80x3 plate steel that has been developed by Sanders and Company Contracting Ltd., sold under the trade-mark ENVIRO-PIPES. A simple calculation of the weight of xc2xdxe2x80x3 plate steel confirms that a mobile crane is required to place this plate structure in a creek bed or remove this structure from the creek bed once the road requires decommissioning. Furthermore, a structure of this size would require a low bed and truck for transport to and from the installation site. Another product on the market comprises a non-corrugated plastic arch. This arch is discussed in the December 1999 issue of Forest Engineering Research Institute of Canadaxe2x80x94Eastern Division. This product is manufactured by KWH Pipe (Canada) Ltd. and is known as the KWH Arch. This product is available to a maximum diameter of 2.3 meters. Once the pipe is cut in half, it expands to 24% larger than its original diameter. Thus the structure becomes somewhat less than half-circle. Since there are no footings along the edges that contact the ground, and with the tension placed on the structure upon installation, the product would tend to sink or be depressed into the banks of the creek bed. This therefore causes further deflection of the pipe from its original less than half circle configuration and compromises the integrity of the structure. There is a real possibility of collapse of the structure under load. A further culvert product is supplied by Armtec Construction Products. Their product is called a xe2x80x9cMini Span Bridgexe2x80x9d. The Mini Span I has a maximum width of 1800 mm. The Mini Span is brought to the site as a one-piece assembled structure. The Mini Span II is available to a width of 3660 mm, making transport of this structure difficult and costly. Required footing and structural support demands trained installers and heavy equipment for installation. This product is also made of galvanized material and other steel components that require treatment to avoid rusting. An article by Soleno Inc. in the November/December 1999 issue of the Canadian Forest Industries describes a product referred to as xe2x80x9cSolArcxe2x80x9d. Installation of the SolArc product requires 8 to 10 cubic meters of logs (one load) to use
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738, 1639, 3934, 6408, 39420, 274, 15297, 416, 23051, 14, 257, 14, 58, 443, 42925, 2896, 5858, 313, 8720, 58, 6920, 2262, 247, 6724, 46650, 12602, 323, 247, 12266, 273, 1384 ]	mean threshold of 10 and standard deviation of 2.5, correlations between pairs of thresholds obtained with 100 reversals each are relatively stable, at 0.67, 0.7, and 0.65 for our 3 lapse rate conditions. This stability in correlations across differing lapse rates happens because lapses alter the mean of the probability distribution of thresholds, but not its relative standard deviation. Checking for consistency of reversal points within a staircase run is another intuitive potential approach to identifying data with lapses. However in the same simulation for 20 reversals, the standard deviation of reversal points was 5.2, 5.4 and 5.4, respectively, providing no information about the presence of the lapses. This probably happens because the range of reversal points is not extended by these lapses but is simply shifted (0% lapses, mean range 9.9–27.2; 5% lapses, 9.9–28.4; 10% lapses, 10.6–29.4). It is worth noting that the lapse rates tested here are purposefully conservative and probably don’t represent the poorest performance that is observed in some studies with children (see, for example, the plots in McArthur & Hogben, 2012). If a participant lapses consistently over a long period during a run of trials, for example, then the effects of this may be visible in the measures tested above. However, these measures clearly do not identify participants who lapse randomly at low rates, despite the impact that these lapses have on the measured threshold estimate. The problem of lapses in psychophysical data is therefore difficult to solve in a satisfying way. An alternative approach to measuring sensory sensitivity, which bypasses the need for obtaining behavioural response from participants, is to use neurophysiological measures. Mismatched negativity (MMN) is an evoked response elicited by a change in a stimulus parameter embedded in a sequence, and which has been used to index sensory sensitivity in a range of developmental settings (Näätänen et al., 2007). The MMN response is modifiable by contributions from sources in the frontal lobes, and is sensitive to the cognitive symptoms of disorders such as schizophrenia, so although considered pre-attentive in origin it is not entirely free of cognitive influence. Bishop (2007) has provided a critical review of the use of this method in research of developmental disorders. It is also possible to construct “cortical psychometric functions” from auditory evoked responses measured with neurophysiological data, a method which shows promise for bias-free estimates of threshold (Witton et al., 2012). Yet there are challenges associated with using neuroimaging techniques with children (Witton, Furlong & Seri, 2013) and for the majority of studies, psychophysics will remain the method of choice. Developing strategies to reduce the likelihood of lapses during adaptive procedures, especially through improving task engagement by children (e.g., Abramov et al., 1984), is therefore critical—as is the use of statistical methods which are sensitive to the limitations of these procedures. Future behavioural studies taking an individual-differences approach (e.g., Talcott, Witton & Stein, 2013) can potentially help improve our understanding of the link between cognitive factors such as attention and memory, and psychophysical performance, especially if these studies make detailed estimates of psychometric functions and lapse rates. Convergent measures, especially physiological measures such as eye-movement recordings, which can monitor a child’s physical engagement with a visual stimulus, would also improve the extent to which researchers can determine the validity of individual trials. Finally, the application of neuroimaging techniques, especially those with high temporal resolution (i.e., MEG and EEG) could provide useful evidence to help unpick the cognitive processes that underpin variable task performance. Conclusions Overall, the findings from the simulations presented here suggest that the accuracy and efficiency of studies using adaptive procedures in untrained and especially paediatric populations are best maximised by very careful choice of adaptive procedure, taking into account the psychophysical properties of the task and stimulus. This should be followed by careful statistical analysis, especially when comparing groups. Investing in innovations able to improve quality time-on-task, particularly for children, in relevant studies will greatly improve data quality, if trial-numbers can be increased. Attempting to index individuals’ lapse rates, and incorporating this information into statistical analyses, would also enable researchers to account for the impact of such differences on experimental findings. Supplemental Information Theoretical convergence points determined by the adjustment rule of a staircase are based on the assumption of a cumulative normal psychometric function. When simulated using a Weibull function, the procedures converge at a very slightly lower value; the 2-down, 1-up staircase converges at 70.2% correct rather than 70.7% after 1,000 reversals. These small differences are negligible in the context of the effects described here. Acknowledgements The authors would like to thank Professor Genevieve McArthur, Dr. Nicholas Badcock, and an anonymous reviewer for their insightful comments on an earlier version of this paper. Additional Information and Declarations Competing Interests The authors declare there are no competing interests. Author Contributions Caroline Witton conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper. Joel B. Talcott conceived and designed the experiments, wrote the paper, reviewed drafts of the paper. G. Bruce Henning conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper. Report a problem Our promise PeerJ promises to address all issues as quickly and professionally as possible. We thank you in advance for your patience and understanding. Type of problem Details 500 characters remaining Follow this publication for updates "Following" is like subscribing to any updates related to a publication. These updates will appear in your home dashboard each time you visit PeerJ. You can also choose to receive updates via daily or weekly email digests. If you are following multiple publications then we will send you no more than one email per day or week based on your preferences. Note: You are now also subscribed to the subject areas of this publication and will receive updates in the daily or weekly email digests if turned on. You can add specific subject areas through your profile settings.May 11 10:25 PM PT11:25 PM MT12:25 AM CT1:25 AM ET1:25 ET5:25 GMT13:25 10:25 PM MST12:25 AM EST11:25 PM CST12:55 AM VEN9:25 UAE12:25 AM CT-Nick Wittgren did not allow a hit or walk in 2.0 scoreless innings as the Cleveland Indians lost to the Oakland Athletics 4-3 on Friday. Wittgren struck out two, ending the game with a 1.32 ERA and 0.73 WHIP on the season. May 8 6:05 PM PT7:05 PM MT8:05 PM CT9:05 PM ET21:05 ET1:05 GMT9:05 6:05 PM MST8:05 PM EST7:05 PM CST8:35 PM VEN5:05 UAE (+1)8:05 PM CT-Nick Wittgren allowed one hit without giving up a run in 1.0 inning as the Cleveland Indians defeated the Chicago White Sox 5-3 on Wednesday. Wittgren did not strike out a batter, ending the game with a 1.54 ERA and 0.86 WHIP on the season. May 6 6:16 PM PT7:16 PM MT8:16 PM CT9:16 PM ET21:16 ET1:16 GMT9:16 6:16 PM MST8:16 PM EST7:16 PM CST8:46 PM VEN5:16 UAE (+1)8:16 PM CT-Nick Wittgren allowed one run on one hit in 0.1 innings as the Cleveland Indians lost to the Chicago White Sox 9-1 on Monday. Wittgren did not strike out a batter, ending the game with a 1.69 ERA and 0.84 WHIP on the season. Apr. 14 2:45 PM PT3:45 PM MT4:45 PM CT5:45 PM ET17:45 ET21:45 GMT5:45 2:45 PM MST4:45 PM EST3:45 PM CST5:15 PM VEN1:45 UAE (+1)4:45 PM CT-Nick Wittgren did not allow a hit or walk in 1.1 scoreless innings as the Cleveland Indians lost to the Kansas City Royals 9-8 on Sunday. Wittgren did not strike out a batter, ending the game with a 0.00 ERA and 0.50 WHIP on the season. Apr. 12 8:29 PM PT9:29 PM MT10:29 PM CT11:29 PM ET23:29 ET3:29 GMT11:29 8:29 PM MST10:29 PM EST9:29 PM CST10:59 PM VEN7:29 UAE (+1)10:29 PM CT-Nick Wittgren allowed one hit without giving up a run in 1.1 innings as the Cleveland Indians lost to the Kansas City Royals 8-1 on Friday. Wittgren struck out two, ending the game with a 0.00 ERA and 0.75 WHIP on the season.Impact of Mesenteric Defect Closure During Laparoscopic Roux-en-Y Gastric Bypass (LRYGB): a Retrospective Study for a Total of 20
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424, 35558, 6098, 1889, 13, 46685, 28, 20091, 13, 35755, 1824, 313, 12373, 1453, 558, 330, 50, 13, 775, 3833, 18101, 460, 313, 10247, 1453, 558, 7956, 13, 18934, 4908, 15, 187, 187, 5180, 20, 5218, 1401, 16927, 6098, 23409, 403, 3559, 347, 9601, 3069, 23015, 28, 295, 30, 22, 15, 23409, 403, 1534, 387, 475, 49, 16160, 17, 15, 1762, 13, 5042, 66, 63, 3118, 1096, 281, 253, 4016, 1453, 13, 5042, 67, 63, 2429, 281, 253, 2762, 1453, 15, 31713, 49, 16160, 17, 15, 1762, 13, 38710, 49, 16160, 17, 15, 520, 13, 22004, 22635, 49, 16160, 17, 15, 2874, 15, 535, 50274, 424, 35558, 6098, 1879, 13, 401, 3460, 28, 20091, 13, 35755, 1824, 28, 495, 6, 53, 1438, 313, 12373, 1453, 582, 495, 6, 53, 855, 5096, 28, 330, 50, 313, 10247, 1453, 582, 10410, 18101, 460, 28, 329, 50, 39, 13, 17515, 6919, 28, 13528, 13, 10410, 45193, 6919, 28, 388, 71, 13, 295, 14, 15741, 1351, 6919, 15, 187, 187, 5180, 21, 5218, 1401, 16927, 6098, 23409, 403, 3559, 347, 9601, 3069, 23015, 15, 5042, 66, 63, 2429, 281, 253, 4016, 1453, 13, 5042, 67, 63, 2429, 281, 253, 2762, 1453, 15, 23409, 403, 1534, 387, 475, 49, 16160, 17, 15, 1762, 15, 38710, 49, 16160, 17, 15, 520, 13, 22004, 22635, 49, 16160, 17, 15, 2874, 15, 535, 50274, 424, 35558, 6098, 1889, 16, 4604, 13, 46685, 16, 39, 3460, 28, 7956, 13, 7306 ]	5,000 mg/kg oral administration. This showed that a lethal dose of 50% is greater than 5,000 mg/kg, which attests that plant products are frequently considered to be safe and have fewer adverse effects than synthetic ones.[@CIT0037] The in vivo antiplasmodial activities of N. Congesta crude extract and solvent fractions were investigated by evaluating the chemosuppression during early infection, while crude extract and aqueous fraction were used to evaluate the curative activity of the plant during established infection (Rane's test). In both suppressive and curative tests, determination of percent parasitemia suppression and improved survival days are the most widely used parameters for antiplasmodial activity screening.[@CIT0031],[@CIT0032] Since 500, 750, and 1,000 mg/kg crude extract and 200, 400, and 600 mg/kg aqueous fraction showed significant parasite suppression, they were further evaluated in curative test.[@CIT0047] In the 4-day chemosuppressive and Rane's test, the highest parasitemia suppression (100%) was recorded in the group treated with positive control (chloroquine), while the lowest parasitemia suppression (0%) was recorded in the group treated with the negative control, distilled water. N. congesta hydromethanolic extract exhibited dose dependent parasitemia suppression and prolonged the survival days of P. berghei infected mice, the highest activity recorded at the maximum dose administered. This is comparable with the activities of the previous reports exhibited by Polyalthia longifolia, Trichilia heudelotii, and melia azedarach.[@CIT0012],[@CIT0027] Parasitemia level in all extract and aqueous fraction treated groups was less than the group treated with negative controls. This revealed that extract and its aqueous fraction had a suppressive effect on the multiplication and erythrocyte infectivity of P. berghei parasites in mice. The hydromethanolic leaf extract of N. congesta suppressed parasitemia by 58.3%, the highest chemosuppression recorded from all the fractions evaluated in the current study. However, at lower concentrations (100, 200, 400 mg/kg), it exhibited insignificant activity as compared to the negative control. This could be attributable to the presence of an insufficient concentration of active principles at lower doses of the extract.[@CIT0015],[@CIT0032] The curative activities were significant at 1,000 mg/kg crude extract at day 7 and 400 and 600 mg/kg of aqueous fraction at days 5--7. Crude extract contains a collection of medicinal compounds and activities of one compound may mask the other or may be potentiated,[@CIT0032],[@CIT0046] hence, fractionation may help to eliminate potentially toxic, inactivating, and/or potentiating compounds.[@CIT0042] Aqueous fraction demonstrated dose dependant higher activity in blood parasitemia suppression against P. berghei than other fractions. The relatively higher activity of the aqueous fraction could be due to secondary metabolites present in crude extract which might be partitioned in the aqueous fraction.[@CIT0032],[@CIT0042] A report from the aqueous fraction of Nuxia species confirmed the presence of iridoid glycosides (mono terpenes),[@CIT0019] which are water soluble[@CIT0048],[@CIT0049] and have antibacterial, anti-inflammatory,[@CIT0050] antioxidant, immune modulating, and pain killing properties.[@CIT0049] These effects are highly associated with antimalarial activities.[@CIT0034],[@CIT0042],[@CIT0047] The MST is a very important parameter to evaluate the antimalarial activity of plant extracts.[@CIT0031] The aqueous fraction prolonged the survival time of P. berghei infected mice dose dependently. This might be due to the presence of secondary metabolites that prevent the overall pathologic effect of the parasite in the infected mice, like anti-inflammatory, antioxidant effects in addition to suppression of the parasite.[@CIT0051] N-hexane fraction did not show any parasitemia inhibition or prolongation of survival days in all dose-treated groups. On the other hand, at higher doses of the fraction the parasitemia level was increased. This could be due to loss of active constituents during fractionation[@CIT0032],[@CIT0042] or the constituents partitioned in this fraction may be immunosuppressants which can lower the immune system.[@CIT0017] The chloroform fraction did not exhibit dose dependent chemosupressive activity, efficacy diminished as the dose increased. This inconsistent effect might be attributed to constituents in the fraction which may follow different kinetics.[@CIT0052],[@CIT0053] In vivo percent mean suppression ≤90% with respect to negative control usually indicates the test compound is active.[@CIT0046] Accordingly, crude extract at 1,000 mg/kg (58.33%), aqueous fraction at 600 mg/kg (44.88%), and chloroform fraction at 200 mg/kg (15%) could be considered to be active against P. berghei. This activity could be attributed to a single or a combination of its secondary metabolites. Temperature and weight reduction are the hallmark of malaria infection in rodent models, indicating that an effective antimalarial agent should prevent temperature and body weight reduction in Plasmodium infected rodents. The dose dependent suppressive activities of the leaves of N. congesta crude extract and water fraction proposes that crude extract and water fraction do not have any toxic effects in experimental mice at the doses evaluated. Our acute oral toxicity study result also indicated that the plant extract was found to be safe at the maximum dose tested (5,000 mg/kg).[@CIT0038] However, tremendous body weight loss has been observed in mice treated with 400 mg/kg of n-hexane and chloroform fractions; this could be attributable to the feed intake depressing effect of metabolites and interfere with the protein digestion by saponins and tannins.[@CIT0054] Conclusion {#S0005} ========== The methanolic extract and aqueous fraction of N. congesta leaves have in vivo anti-malarial activities. The antimalarial activity and lack of acute toxicity is suggested to uphold the earlier claims made by the Ethiopian traditional practitioners. The authors are thankful to the University of Gondar for Funding the Study. Abbreviations {#S0006} ============= ACT, Artemisinin-based Combination Therapy; ANOVA, Analysis of Variance; OECD, Organization for Economic Cooperation and Development; IP, Intraperitoneal; MST, Mean Survival Time; PBS, Phosphate Buffered Saline; PCV, Packed cell volume; PRBCs, Packed red blood cells; RBC, red blood cell; SEM, Standard Error of Mean; SPSS, Statistical Package for the Social Sciences; WHO, World Health Organization. Ethics Approval {#S0007} =============== All the experiments were conducted in accordance with internationally accepted laboratory animal use, care, and guidelines. Ethical approval for the study was obtained from the Department of Pharmacology/University of Gondar Ethics and Research Committee, Gondar-Ethiopia (SOP4/78/09). Data Sharing Statment {#S0008} ===================== Almost all the materials and data of our study are included in the manuscript, some of the material and data will be available to other researchers upon reasonable request. Authors' Information {#S0009} ==================== Mss Melshew Fenta (MSc), University of Gondar Specialized Referral Teaching Hospital, University of Gondar, P.O.Box 196, Gondar, Ethiopia, e-mail: <[email protected]>. Author Contributions {#S0010} ==================== All authors have made substantial contributions in the conception and design, acquisition of data, analysis, and interpretation of data;All authors have made substantial contributions in drafting the article, and revising it critically for important intellectual content;All authors approved the final version the manuscript to be published;All authors have agreed on the work and have given final approval of the version to be published. Disclosure {#S0011} ========== The authors have no conflict of interest to disclose. [^1]: Notes: + = present, − = absent. [^2]: Notes: Values are presented as Mean±SEM; n=5. ^a^ compared to the negative control, ^b^ compared to the positive control. \*P\<0.05, \\P\<0.01, \\\*P\<0.001. Abbreviations: Ex, Extract; DW, distilled water (negative control); CQ, Chloroquine (positive control); CE, crude extract. [^3]: Notes: Values are presented as Mean±SEM; n=5. Values are significant at P\<0.05, ^a^compared to the negative control, ^b^ compared to the positive control. \*P\<0.05, \\P\<0.01, \\\*P\<0.001. Abbreviations: Fr, Fraction; DW, distilled water; 3%T80 (negative control), 3%Tween 80; CQ (positive control), chloroquine; AQF, aqueous fraction; CF, chloroform fraction; Hf, n-hexane fraction. [^4]: Notes: Values are presented as Mean±SEM. ^a^ compared to the negative control, ^b^ compared to the positive control. Values are significant at P\<0.05. \\P\<0.01, \\\*P\<0.001. Abbreviations: Ex/Fr, Extract/Fraction; CE, Cr
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]	://www.espncricinfo.com/magazine/content/story/137311.htmlThu, 12 Apr 2018 17:29:59A marvellous symphonyThe innuendo of the past few months must have sat heavily even on Sachin Tendulkar's those broad shoulders, and today's riposte - though lacking the amazing grace of Laxman's knock - will give him immense satisfactionhttp://www.espncricinfo.com//content/story/137309.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137309.htmlThu, 22 Mar 2018 04:04:19Tendulkar and Laxman dazzle the SCGIt could not have been a better day for Indiahttp://www.espncricinfo.com//content/story/137307.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137307.htmlTue, 20 Mar 2018 18:11:54Tendulkar and Laxman dazzle the SCGIt could not have been a better day for Indiahttp://www.espncricinfo.com/australia/content/story/137306.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137306.htmlThu, 12 Apr 2018 17:22:43Making the batsmen playAt the end of first day of the first Test of the new year, India were 284 for threehttp://www.espncricinfo.com/australia/content/story/137298.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137298.htmlThu, 12 Apr 2018 17:29:59Tendulkar's resilienceAt the end of first day of the first Test of the new year, India were 284 for threehttp://www.espncricinfo.com//content/story/137296.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137296.htmlThu, 12 Apr 2018 17:22:41'If I can stay for three hours, I can stay for three more'Just like his batting, Akash Chopra has a confidence that is not demonstrativehttp://www.espncricinfo.com//content/story/137294.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137294.htmlThu, 12 Apr 2018 17:22:42A beautiful struggleAfter the horror patch that he has been through, a sparkling century wouldn't be an appropriate signpost to better timeshttp://www.espncricinfo.com//content/story/137289.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137289.htmlThu, 12 Apr 2018 17:29:56'Indian' Australians and spilt chancesGuess who flew down to boost the confidence of the Indian cricket team before the most important Test match of their liveshttp://www.espncricinfo.com/magazine/content/story/137288.html?CMP=OTC-RSS http://www.espncricinfo.com/magazine/content/story/137288.htmlThu, 12 Apr 2018 17:29:58'Indian' Australians and spilt chancesGuess who flew down to boost the confidence of the Indian cricket team before the most important Test match of their liveshttp://www.espncricinfo.com/magazine/content/story/137287.html?CMP=OTC-RSS http://www.espncricinfo.com/magazine/content/story/137287.htmlThu, 12 Apr 2018 17:29:57Sehwag and Tendulkar prop up IndiaThe young apprentices served up a fine entrée in the final Test between Indian and Australia at the Sydney Cricket Ground, and then the modern masters got down to the task of preparing a substantial main coursehttp://www.espncricinfo.com//content/story/137282.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137282.htmlThu, 12 Apr 2018 17:22:43Sehwag and Tendulkar prop up IndiaThe young apprentices served up a fine entrée in the final Test between Indian and Australia at the Sydney Cricket Ground, and then the modern masters got down to the task of preparing a substantial main coursehttp://www.espncricinfo.com/australia/content/story/137280.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137280.htmlThu, 12 Apr 2018 17:22:44#define _CRT_SECURE_NO_WARNINGS #include <stdio.h> #include<stdint.h> #include <Winsock2.h> // need link with Ws2_32.lib #pragma comment(lib,"ws2_32.lib") #include<pcap.h> #pragma comment(lib,"wpcap.lib") #include<memory.h> #include <stdlib.h> #include <sys/types.h> #include "data.h" #include <windows.h> #include<atlbase.h> #include<atlconv.h> #include"iphlpapi.h" #pragma comment(lib, "Iphlpapi.lib") uint8_t BroadcastAddr[6] = { 0xff, 0xff, 0xff, 0xff, 0xff, 0xff }; // 广播MAC地址,Broadcast const uint8_t MultcastAddr[6] = { 0x01, 0x80, 0xc2, 0x00, 0x00, 0x03 }; // 多播MAC地址,neareast typedef enum { REQUEST = 1, RESPONSE = 2, SUCCESS = 3, FAILURE = 4, H3CDATA = 10 } EAP_Code; typedef enum { IDENTITY = 1, NOTIFICATION = 2, MD5 = 4, AVAILABLE = 20 } EAP_Type; static int times = 20;//重复请求的次数 typedef struct setting { char device[100]; uint8_t mac[6]; }Setting; void SendStartPkt(pcap_t handle, uint8_t localmac[6]); void GetMacFromDevice(uint8_t mac[6], const char devicename); int GetNameMacfromDevice(uint8_t mac[6], char devicename[100]); void SendResponseIdentity(pcap_t adhandle, const u_char pkt_data, uint8_t localmac[6]); void SendResponseMD5(pcap_t adhandle, const u_char pkt_data); long file_size(char filename); / 回调函数，当收到每一个数据包时会被libpcap所调用 / void packet_handler1(u_char param, const struct pcap_pkthdr header, const u_char pkt_data) { struct tm ltime; char timestr[16]; ether_header eh; x802_header uh; eap_header eaph; time_t local_tv_sec; //eap数据 u_char version;//802.1x版本号 u_char type;//eap的类型0--eap,1--eapol u_short len;//eap数据包长度,包括首部 int i = 0; u_char code;//request--1,respond--2 u_char id;//数据id u_char eap_type;//1--identity,--md5-challenge,3--legacy_Nak //将地址转化为可视结构 unsigned char eh_dst[6] = {0}; //目的地址 unsigned char eh_src[6] = {0}; //源地址 /* 将时间戳转换成可识别的格式 / local_tv_sec = header->ts.tv_sec; ltime = localtime(&local_tv_sec); strftime(timestr, sizeof timestr, "%H:%M:%S", ltime); / 打印数据包的时间戳和长度 */ printf("%s.%.6d len:%d ", timestr, header->ts.tv_us
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5682, 32613, 285, 253, 17879, 457, 84, 6277, 13675, 10207, 13, 1481, 273, 326, 6757, 457, 84, 16660, 68, 14628, 4828, 49587, 6757, 275, 1457, 2816, 432, 8441, 281, 7544, 13, 898, 16, 883, 812, 452, 644, 14415, 13, 17025, 8219, 15, 13675, 10207, 285, 473, 457, 41437, 13, 2032, 281, 830, 13, 497, 17123, 28851, 13, 7392, 272, 253, 43497, 273, 253 ]	Crane had handed them fossilized dinosaur excrement. Then, linking the stones to the work they were about to do [under the direction of Petraeus], Crane warned that their final work product shouldn’t simply be a polishing of old crap. He had their attention.” With this anecdote, Forrester had my attention. I tend to nod off reading most business books, not (I hope) because of my advanced age but rather because they represent polishing of old shit, shibboleths I’ve seen hundreds of time before. There was no nodding off as I absorbed the way-out-of-the-box case studies Forrester presents in a book that should be read by everyone in a position of power in any organization. “Consider” is a guide to reflection and consideration for decision-making in the twenty-first century. Instead of urging us to keep focused on the problem at hand, Forrester in many cases tells us to Stop Before We Screw Up, or as Dr. Robert Bea drills into his Civil and Environmental Engineering students at the University of California in Berkeley: “STOP, THINK, AND DONT DO SOMETHING STUPID!” This is the warning Bea wants to dramatize what he terms the inevitable “oh shit” moments that present themselves — before an actual engineering calamity like the April 2010 Deepwater Horizon/BP disaster happens. Maybe it will turn out that Tokyo Electric Power Company (TEPCO), the operators of the damaged nuclear reactors in northeast Japan, made similar errors in the wake of the earthquake and tsunami of March 11. The stories and examples that Forrester presents in “Consider” demonstrate that the best decisions, insights, ideas and outcomes result when we take sufficient time to think and reflect. This seems to be an obvious rule, but the author emphasizes that our always-on wireless technology allows us to act and react more quickly than ever before. This isn’t a good thing because we are taking increasingly less time to consider our decisions before we make them. Reflection supplies an arsenal of ideas and solutions to the right problems. In addition to interviews of leaders such as Petraeus, Forrester talks to California attorney Brooksley Born, former head of the Commodity Futures Trading Commission, and Dallas, Texas-based global investor Kyle Bass, who saw the worldwide meltdown coming as early as 2005, three years before it body-slammed the world. Bass’s foresight helped make money for his clients, rather than wiping them out. Forrester shows us that taking time and giving ourselves the mental space for reflection can mean the difference between total success and total failure. I was reminded of Charles Ferguson’s Oscar-winning feature documentary, “Inside Job” as I read in “Consider” how Iceland’s economy was ruined by the nation’s headlong rush into investing in the kind of unregulated new financial products Brooksley Born warned the Clinton Administration, and particularly Treasury Secretary Robert Rubin, about, to no avail. “Inside Job” has a “cold start” beginning (starting the film before the opening credits) concentrating on Iceland’s predicament. It’s a nation of less than 400,000 people, but similar mistakes were made in Greece, Hungary, Spain and — of course– the United States. We need more people like Brooksley Born, Kyle Bass, Robert Bea, David Petraeus and the others cited and/or interviewed by Forrester in his must-read book. And we need to turn off the distracting wireless devices and do some really deep thinking. About the author Daniel Patrick Forrester is a management consultant with over fifteen years experience leading complex strategy and technology evolution engagements for senior executives from Fortune 100 and 500 companies, and federal government organizations. Current and past clients include: Verizon, Sallie-Mae, Sprint, Dow Chemical, FMC Corporation, The Department of Homeland Security, The Library of Congress, The Congressional Research Service, and the United States Marine Corps. Forrester is frequently in demand as a public speaker at organizations such as The Brookings Institute and the top-ranked Booth School of Business at the University of Chicago. He is currently a Director and Executive within Sapient Government Services, a subsidary of Sapient Corporation. Reviewed by David M. Kinchen “Wherever you are, death will find you, even in the looming tower” – from the 4th Sura of the Quran, spoken by Osama bin Laden on a videotaped speech found on a computer taken from the Hamburg, Germany al-Qaeda cell Editor’s Note: This review was originally published on Sept. 11, 2006. It is being published again to coincide with Lawrence Wright’s visit to Huntington, West Virginia on Thursday, Sept. 29, 2011. To employ the often useful – and truthful cliché – if you read only one book on Osama bin Laden, Al-Qaeda and Islamist terrorism, that book should be “The Looming Tower: Al-Qaeda and the Road to 9/11” by New Yorker writer Lawrence Wright (Knopf, 480 pages, $27.95, illustrations, sources, cast of characters, bibliography, index). About that back-of-the-book feature “Principal Characters”: It’s absolutely essential — with all the Arab names in this book – to get them straight. More books should include them, as well as the voluminous notes, sources, persons interviewed, etc. in this exceptionally well documented book that immediately joins my short list of contenders for top prize books of 2006. By telling the story of the spiritual father of bin Laden’s form of Islamism, Sayyid Qutb, who studied in Greeley, CO in 1948, Wright places fundamentalist Islam in context. Qutb was a middle-class Egyptian who was both entranced and appalled by the diversity of America, where people of various nationalities and religions seemed to get along, albeit with much literal and physical jostling. Qutb traveled widely in the U.S. and was particularly entranced – and appalled – by the vitality of New York City, in sharp contrast to the decadence of Cairo in the last days of King Farouk’s regime. After discussing Qutb’s variety of fundamentalist Islam and its influence on young Muslims of all nationalities – Qutb was hanged by Nasser in 1966 – Wright concentrates his narrative four individuals: Osama bin Laden and Ayman Zawahiri, the leaders of al-Qaeda (Arabic for “The Base”) founded in Afghanistan in 1988 in the last days of the Soviet occupation; colorful FBI Agent John O’Neill, who died in the attack on the World Trade Center five years ago and Saudi Arabia’s former head of intelligence, Prince Turki al-Faisal, who started out as ally of bin Laden and ended up as his bitter enemy after the Saudi millionaire declared jihad on the Saudi leaders. Most of the emphasis is on bin Laden and O’Neill. If there’s one thing that comes through clearly from “The Looming Tower,” it’s that the widely held belief that intelligence agencies hoard their scraps of intelligence like animals crowding around a downed prey animal, unwilling to share with anyone, is absolutely true. The rivalry between the Central Intelligence Agency and the FBI is particularly well-drawn by Wright, an indefatigable reporter and elegant writer. O’Neill, was a working class guy from Atlantic City, NJ, who loved the New York metropolitan area. He dressed like a dapper Mafia don in Burberry pin-striped suits and expensive Italian shoes – in contrast to his cheap-suit-wearing colleagues – and tried to break down this great intelligence divide, often to the annoyance of his boss, FBI Director Louis Freeh. O’Neill, who was 50 when he died in the 9/11 attacks soon after his resignation and just into his new job as security director of the WTC, is wonderfully profiled by the New Yorker writer, which makes sense since the “profile” as we know it today was invented at the magazine decades ago under the editorship of Harold Ross. At the time of the Khobar Towers bombing in August 1996, there were only seven Arabic speaking FBI agents in the entire nation, Wright notes, pointing out that the FBI was largely staffed by men of urban Irish and Italian background. One of the seven, Lebanese-American Ali Soufan, was assigned to work with O’Neill on the investigation of the USS Cole bombing; the interrogation by this loyal American of Lebanese birth of Abu Jandal in Yemen after 9/11 was instrumental in identifying the 9/11 hijackers. He now works for Rudy Giuliani’s security firm. O’Neill comes through in Wright’s narrative as one of the few intelligence officers in the nation to understand the dangers of Islamic terrorism, which really is amazing considering the events of the first attack on the World Trade Center in 1993. O’Neill, in charge of a New York-based task force dedicated to capturing Ramzi Yousef, the mastermind of the 1993 WTC attack, had to deal with general tone-deafness toward Islamic terrorism that characterized both the Clinton and Bush Administrations. Yousef was captured in 1995 and now is in prison for life. With more interagency cooperation and more leaders listening to O’Neill, his colleague and Islamism expert Dan Coleman and the CIA’s Michael Scheuer, head of that agency’s Alec Station counterterrorism agency in New York from 1996 to 1999, 9/11 could have been prevented, Wright argues. Scheuer and O’Neill, true to form, were bitter rivals, echoing the rivalry of the
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(-16)/2418/(-4). Suppose db + 313 = -185. Let g = b - -819. Is g a composite number? False Let z be -1 - 2 - (-8 - -4). Let l be 80(z + 3 - 2). Suppose -l - 1 = -u. Is u prime? False Let h be (-2)/14 - 4/(-28). Suppose 4f - 25 + 1 = h. Is (-4)/f(-42)/4 a prime number? True Let z = -5680 - -8039. Is z a prime number? False Suppose 105m - 101m = 12. Suppose j + 5q - 57 = 0, -2q + 365 = 5j + mq. Is j a composite number? True Let h be (16/12)/(4/6). Suppose 0r + 4 = hr. Suppose -118 + 2 = -rd. Is d prime? False Is (2/8)/(-17(-12)/2659344) prime? True Let k be ((-9)/(-27))/((-1)/(-21)). Let s be k/((-21)/9) - 6. Let a(w) = -14w + 1. Is a(s) composite? False Let m = 11056 + 2287. Is m composite? True Let f = -83665 + 149556. Is f prime? False Is (43 + -17778)/((-2)/(12)) a composite number? True Suppose 2v + 3c + 3 = 0, -3c - 12 = v + 2c. Is ((v - 3)/3 - 3) + 169 a composite number? True Let a = 20011 - 13058. Suppose 5b - a = t, b + 3t + 238 = 1635. Is b composite? True Let q(c) = 77c + 974. Is q(69) prime? True Let b(n) = -38n - 15. Let r be b(-12). Suppose 3z = -9, -4t = -7t + 4z + r. Is t composite? True Suppose 3t - 19321 = 2y, -4y - 5968 - 13363 = -3t. Is t a prime number? False Let f(h) = -h. Let c = 10 - 15. Let s(y) = -16y*3 + 2y*2 - y + 3. Let n(j) = cf(j) + s(j). Is n(-2) composite? False Let j(s) = 3150s + 61. Is j(4) prime? False Let m(p) = 4p*2 + 70p - 169. Is m(47) composite? True Suppose 10q = 5q + 115. Suppose -5v + q = 3, 5f - v - 3161 = 0. Is f composite? True Suppose 0 = -2j + 2p + p + 21, 4p + 18 = j. Suppose 5518 = 8x - jx. Is x a prime number? False Let s be ((-12)/(-4))/(6/4). Let n be s1/(4At SAGlobal, it’s our people who set us apart We are a community and culture of individuals who think innovatively to deliver business transformational solutions to address our clients’ toughest challenges. Whether you are looking for an opportunity to launch a career working side-by-side with a global network of highly experience talented professionals, or you want to bring years of industry expertise to bear on the next step in your professional development, SAGlobal has opportunities for you. Learn from senior consultants, who come with 14+ years of implementation experience Join us and learn from the world’s largest Dynamics pool of professionals Enhance your Dynamics implementation experience with our employees who have implemented Dynamics across more than 76 countries Our Culture We believe true culture in our company is built through Teamwork, Openness and Experience. With over 500 employees speaking over 45 languages across 25 nationalities and 18 countries, we pride ourselves on being a truly diverse organisation, combining an international footprint with in-depth knowledge on local markets. Our pervasive sense of shared values and business practices that get baked into our project execution help us feel and behave as one team across the different markets and business functions. Our success as a business depends on the success of our people. So we make sure that we create an environment where all our employees feel included and are able to perform at their best. We have a culture where success is celebrated, no matter how big or small. We trust each other and value openness and honesty in our working relationships. We help you build your career You can expect us to nurture your strengths and value your unique perspectives, and in return we expect you to share our passion for doing good. Providing our people with international experiences in line with their career aspirations, skills, experience and strengths is an important part of our development approach. We continually look for additional ways to reward our employees. Our employees enjoy competitive pay and excellent benefits, along with a positive work environment built on mutual respect and professionalism.Stereotactical fields applied in proton spot scanning mode with range shifter and collimating aperture. Some clinical indications require small fields with sharp lateral dose gradients, which is technically challenging in proton beam therapy. This holds especially true for low-range fields applied with the spot scanning technique, where large beam profiles entering from the beam-line or the insertion of range shifting blocks lead to large lateral gradients. We regard the latter case and solve it by shifting the range shifting block far upstream in conjunction with a collimating aperture close to the patient. The experiments of the current work are based on a commercial proton therapy treatment head designed for several delivery modes. In a research environment of the spot-scanning delivery mode a range shifter is inserted downstream of the scanning magnets in a slot which is usually employed only in a scattering delivery mode. This configuration is motivated by equations assuming a simple model of proton transport. In the experiments lateral dose planes are acquired with a scintillation screen and radiochromic films. Dose distributions are calculated with the Monte Carlo dose engine of the RayStation treatment planning system. We demonstrate that proton fields with 80%-20% lateral dose fall-off values between 1.4 mm and 4.0 mm can be achieved for water equivalent depths between 0 cm and 10 cm. The simulated lateral dose profiles agree with the experimental dose profiles. The sharpening of the field edges is set off by a broadening of the proton spots towards the center of the fields. This limits the clinical application mainly to small fields for which the distal and proximal conformality is of minor importance.The 3 night New Edition Story was produce well and shared very private events in the group’s life. The rollercoaster ride starts with the infamous Home Again fight and ends with the BET 25 year performance. The casting of the NE members were outstanding. The younger cast of Jahi, Tyler, Dante, Caleb, & Myles transition to the adult cast of Algee, Woody, Elijah, Kieth, and Yazz was one of my favorite scenes.The increasingly popular practice of 'vaginal seeding'—in which cesarean-delivered babies are immediately swabbed with the mother's vaginal fluids—is declared unjustified and potentially unsafe in a new critical review of scientific literature. Differences between the bacteria and other microorganisms (microbiome) in cesarean- and vaginally born babies are thought to account for the greater risk of health problems suffered by cesarean-born babies in later life. However as outlined in the study, published in Frontiers in Medicine, this difference is most likely caused by antibiotics administered to mothers delivering by C-section rather than not being exposure to vaginal microbes. Breastfeeding duration, maternal obesity and age at birth can also account for microbiome differences. "After reviewing the scientific evidence, we find no support for the 'bacterial baptism' hypothesis," says Lisa Stinson, who completed this analysis at the Division of Obstetrics and Gynecology, The University of Western Australia. "While we know that cesarean delivery impacts the infant microbiome, it's very unlikely these differences are caused by a lack of exposure to vaginal microbes at birth." Babies born by cesarean section are at greater risk of suffering from asthma, allergies, autoimmune disorders and obesity in later life, which in turn have been related to differences in a baby's microbiome—the microorganisms associated with its skin, mouth, nose and gut. "My research involves working with a lot of mothers who are delivering by C-section and some mothers show an interest in vaginal seeding after reading about it on the internet. Understandably, they want to give their babies the best start in life and on the surface this practice makes sense," Stinson explains. "But there are certain risks, such as unintentionally transferring dangerous bacteria or viruses to the newborn, so we wanted to find out if these risks were justified." Stinson performed a thorough review of research detailing bacterial populations associated with newborns, how these change from when the baby is born, and whether there were differences associated with the mode of delivery or other factors such as antibiotic administration, breastfeeding and age at birth. The story that emerged was complex: It
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sale of the Properties to Purchaser, or for the Purchaser to negotiate a purchase of the Properties from the owner(s).” J.A. at 228. Appellee’s acceptance of the purported offer would have created neither a final purchase contract nor a preliminary contract requiring future negotiations. It was, at best, an invitation to commence negotiations, and such an invitation does not constitute an offer. See generally Chiapparelli v. Baker, Kellogg & Co., 169 N.E. 274, 275 (N.Y. 1929) (“Frequently negotiations for a contract are begun between parties by general expressions of willingness to enter into a bargain upon stated terms and yet the natural construction of the words and conduct of the parties is rather that they are inviting offers, or suggesting the terms of a possible future bargain than making positive offers.” (internal quotation marks and citation omitted)). Because there was no offer, Appellant’s right of first refusal was never triggered, and its claim for specific performance fails as a matter of law. Accordingly, we AFFIRM the judgment of the district court. FOR THE COURT: Catherine O’Hagan Wolfe, Clerk of Court 3 Muni was adopted by a security guard After he passed away, his wife dumped Muni back to the guard house.Muni used to live in an apartment and not familiar with outside world.I took him in since I don't think he can survive being a stray.Please help Muni by fostering or adopting.He is a friendly dog.Thank you.Related literature {#sec1} ================== For background to Schiff bases and their applications, see: Dao et al. (2000[@bb5]); Eltayeb & Ahmed (2005a [@bb6],b [@bb7]); Karthikeyan et al. (2006[@bb9]); Sriram et al. (2006[@bb12]). For related structures, see: Eltayeb et al. (2009[@bb8]); Tan & Liu (2009[@bb13]). For bond-length data, see: Allen et al. (1987[@bb1]). For hydrogen-bond motifs, see: Bernstein et al. (1995[@bb2]). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986[@bb4]). Experimental {#sec2} ============ {#sec2.1} ### Crystal data {#sec2.1.1} C~17~H~17~NO~3~M ~r~ = 283.32Orthorhombic,a = 14.719 (3) Åb = 9.1302 (16) Åc = 20.597 (4) ÅV = 2768.0 (9) Å^3^Z = 8Mo Kα radiationμ = 0.09 mm^−1^T = 100 K0.50 × 0.15 × 0.02 mm ### Data collection {#sec2.1.2} Bruker APEX DUO CCD area-detector diffractometerAbsorption correction: multi-scan (SADABS; Bruker, 2009[@bb3]) T ~min~ = 0.955, T ~max~ = 0.99816563 measured reflections4056 independent reflections2744 reflections with I \> 2σ(I)R ~int~ = 0.073 ### Refinement {#sec2.1.3} R\[F ^2^ \> 2σ(F ^2^)\] = 0.052wR(F ^2^) = 0.141S = 1.004056 reflections254 parametersH atoms treated by a mixture of independent and constrained refinementΔρ~max~ = 0.39 e Å^−3^Δρ~min~ = −0.29 e Å^−3^ {#d5e511} Data collection: APEX2 (Bruker, 2009[@bb3]); cell refinement: SAINT (Bruker, 2009[@bb3]); data reduction: SAINT; program(s) used to solve structure: SHELXTL (Sheldrick, 2008[@bb10]); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL and PLATON (Spek, 2009[@bb11]). Supplementary Material ====================== Crystal structure: contains datablocks global, I. DOI: [10.1107/S160053681000838X/ci5052sup1.cif](http://dx.doi.org/10.1107/S160053681000838X/ci5052sup1.cif) Structure factors: contains datablocks I. DOI: [10.1107/S160053681000838X/ci5052Isup2.hkl](http://dx.doi.org/10.1107/S160053681000838X/ci5052Isup2.hkl) Additional supplementary materials: [crystallographic information](http://scripts.iucr.org/cgi-bin/sendsupfiles?ci5052&file=ci5052sup0.html&mime=text/html); [3D view](http://scripts.iucr.org/cgi-bin/sendcif?ci5052sup1&Qmime=cif); [checkCIF report](http://scripts.iucr.org/cgi-bin/paper?ci5052&checkcif=yes) Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: [CI5052](http://scripts.iucr.org/cgi-bin/sendsup?ci5052)). The authors thank the Malaysian Government, the Ministry of Science, Technology and Innovation (MOSTI) and Universiti Sains Malaysia for the E-Science Fund and RU research grants (PKIMIA/613308, PKIMIA/815002, and PKIMIA/811120). NEE thanks Universiti Sains Malaysia for a post-doctoral fellowship and the International University of Africa (Sudan) for providing study leave. The authors also thank the Malaysian Government and Universiti Sains Malaysia for the Research University Golden Goose grant No. 1001/PFIZIK/811012. Comment ======= Schiff bases have received much attention because of their potential applications. Some of these compounds exhibit various pharmacological activities, as noted by their anticancer (Dao et al., 2000), anti-HIV (Sriram et al., 2006), antibacterial and antifungal (Karthikeyan et al., 2006) properties. In addition, some of them may be used as analytical reagents for the determination of trace elements (Eltayeb & Ahmed, 2005a,b). Previously we have reported the crystal structure of 2-((E)-{2-\[(E)-2,3-dihydroxybenzylideneamino\]-5-methylphenyl}- iminiomethyl)-6-hydroxyphenolate (Eltayeb et al., 2009) which exists in a zwitterionic form. The title compound is another schiff base which also crystallizes in a zwitterionic form. Herein we report its crystal structure. The title molecule exists in a trans configuration about the C═N double bond \[1.3129 (19) Å\], with a C6--N1--C7--C8 torsion angle of 178.13 (14)°. The molecule is slightly twisted, with the dihedral angle between the two benzene rings being 13.42 (7)°. The hydroxy group is coplanar with the attached C1--C6 benzene ring. The methoxy group is coplanar with the attached C8--C13 benzene ring \[C14---O3---C12---C11 = 2.1 (2)°; r.m.s. deviation of 0.0384 (1) Å for the eight non H atoms\]. The allyl unit (C15--C17) is in an (-)-anticlinal conformation as indicated by the C11---C10---C15---C16 torsion angle of -94.28 (18)°. An intramolecular N---H···O hydrogen bond between the NH^+^ and the phenolate O^-^ groups generate an S(6) ring motif (Fig. 1 and Table 1) (Bernstein et al., 1995). The bond distances show normal values (Allen et al., 1987) and are comparable with those observed in related structures (Eltayeb et al., 2009; Tan & Liu, 2009). In the crystal packing (Fig. 2), molecules are linked into zigzag chains along the \[010\] by O---H···O hydrogen bonds involving hydroxy groups, phenolate and methoxy O atoms (Table 1). Within a chain, the adjacent molecules are approximately perpendicular to each other (Fig. 2). The crystal structure is further stabilized by weak intermolecular C---H···π interactions (Table 1) involving the C8--C13 ring (centroid Cg1). Experimental {#experimental} ============ The title
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\widetilde{\mathcal{M}}^B(g,n^-,n^+) \ar[rr]^{\cong} & & \widetilde{\mathcal{M}}^P(g,n^-,n^+) .}$$ The horizontal isomorphisms are given in Theorems \[MPMBiso\] and \[th:puncture\_rigged\_equiv\]. The projection maps are defined in , , , and . Checking commutativity is routine. Producing such a diagram was one of the goals of this project. It gives a full relation between the puncture and and border picture at both the moduli space and Teichmüller space levels. Before formulating a concluding theorem we need to show that $P_{\mathrm{mod}}$ is holomorphic. \[le:Pmod\] The action of $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ on $\widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ is properly discontinuous and fixed-point free. The projection $P_{\mathrm{mod}}$ is holomorphic and possesses local holomorphic sections. The bijection $\mathcal{J} : {\widetilde{T}^{B}_{\#}}({\ensuremath{\Sigma_{}}}^B) \to \widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ from Theorem \[th:puncture\_rigged\_equiv\] is a biholomorphism by the commutativity of the top triangle in Diagram and the existence of local holomorphic sections of $P_{\mathrm{DB}}$ and $P_{\mathrm{DB}}^{\#}$ (Corollaries \[riggedTPcomplex\] and \[trandtb\]). The actions of $\mathrm{DI}$ on ${\widetilde{T}^{B}_{\#}}({\ensuremath{\Sigma_{}}}^B)$ and $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ on $\widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ can be seen to be equivalent by directly using the definitions of the actions and the isomorphism $\mathcal{J}$. The required properties of the action now follow from Corollary \[TRandMiso\] and its proof. In Lemma \[PModonriggedTP\] we showed that the action of $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ is by biholomorphisms. Thus Proposition \[complex\_quotient\] guarantees the stated properties of $P_{\mathrm{mod}}$. \[th:resultssummary\] 1. All the spaces in Diagram are obtained from $T^B({\ensuremath{\Sigma_{}}}^B)$ by quotienting by the action of the mapping class group and certain subgroups. (Proposition \[Pmodquotient\], Theorem \[th:TBTPiso\] and Corollaries \[trandtb\] and \[TRandMiso\]. ) 2. These actions are by biholomorphisms and are properly discontinuous and fixed-point free. (Lemmas \[Modaction\_holo\], \[ModactionTP\], \[fixed-point-free\], \[propdisc\] and \[PModonriggedTP\] and Lemma \[le:Pmod\].) 3. With the complex structures inherited from $T^B({\ensuremath{\Sigma_{}}}^B)$, all the spaces in Diagram become complex Banach manifolds. (Proposition \[complex\_quotient\], Theorem \[th:complex\_moduli\], Corollaries \[riggedTPcomplex\], \[trandtb\] and \[TRandMiso\] and Lemma \[le:Pmod\].) 4. These complex structures are the unique ones that make all the maps holomorphic. All the maps possess local holomorphic sections. (Proposition \[complex\_quotient\].) 5. The horizontal bijections become biholomorphisms. (Commutativity of the diagram and existence of local holomorphic section) 6. The complex structures on the moduli spaces are independent of the choice of base surface ${\ensuremath{\Sigma_{}}}^B$ and its boundary trivialization ${\boldsymbol{\tau}}$. (Theorem \[unique\_complex\].) [Holomorphicity of Sewing]{} \[se:holo\_sewing\] As discussed in Section \[introduction\], the sewing operation is the fundamental geometric operation in conformal field theory. Holomorphicity of this operation is required in the case of chiral CFTs, or more formally, in the definition of a weakly conformal field theory. In Section \[sewing\] the sewing operation was defined for the case of quasisymmetric boundary parametrizations. We now express this operation as a map between both the rigged moduli and Teichmüller spaces. These sewing maps are shown to be holomorphic. One advantage of working with quasisymmetric maps is the conceptually satisfying way in which the sewing maps can be defined and the holomorphicity proved. Recall from Section \[Teichmuller\] that for a bordered Riemann surface, ${\ensuremath{\Sigma_{}}}^B$, the Teichmüller space $T^B({\ensuremath{\Sigma_{}}}^B)$ is endowed with the standard complex structure through the use of the Bers embedding (see [@Nag Chapter 3] or [@Lehto V.5.]). With this structure the fundamental projection $\Phi_{{\ensuremath{\Sigma_{}}}^B}: L^{\infty}_{(-1,1)}({\ensuremath{\Sigma_{}}}^B)_1 \rightarrow T^B({\ensuremath{\Sigma_{}}}^B)$ is holomorphic, and has a local holomorphic section in a neighborhood of every point. Note that the projection $P_{{\ensuremath{\Sigma_{}}}^B}: T^B({\ensuremath{\Sigma_{}}}^B) \rightarrow \widetilde{\mathcal{M}}(g,n^-.n^+)$ from can be defined by first projecting $$T^B({\ensuremath{\Sigma_{}}}^B) \to T^B({\ensuremath{\Sigma_{}}}^B) / {\mathrm{PModI}({{\ensuremath{\Sigma_{}}}^B})}$$ and following with the isomorphism $[{\ensuremath{\Sigma_{}}}^B,f,{\ensuremath{\Sigma_{1}}}^B] \mapsto [{\ensuremath{\Sigma_{1}}}^B, {\boldsymbol{\tau}} \circ f^{-1}]$ of Theorem \[TBcoversMB\]. It can be checked directly that $P_{{\ensuremath{\Sigma_{}}}^B} =P_{\mathrm{DI}} \circ P_{\mathrm{DB}^{\#}}$. From Theorem \[th:complex\_moduli\] we know that the projection $P_{{\ensuremath{\Sigma_{}}}^B}$ is holomorphic and has local holomorphic sections near every point. Actually this projection was used to induce the complex structure on $\widetilde{\mathcal{M}}(g,n^-.n^+)$. We now recall the sewing operation described in Section \[sewingoperation\]. To avoid excessive decorations, we change notation and let $X$ and $Y$ be bordered Riemann surfaces of type $(g_X, n^-_X, n^+_X)$ and $(g_Y, n^-_Y, n^+_Y)$ respectively where $n^+_X >0$ and $n^-_Y>0$. Let ${\boldsymbol{\tau}}_X = (\tau_X^1, \ldots \tau_X^{n_X})$ and ${\boldsymbol{\tau}}_Y = (\tau_Y^1, \ldots,\tau_Y^{n_Y})$ be (quasisymmetric) boundary trivializations of $X$ and $Y$ respectively (see Section \[capsewing\]). Choose $i$ and $j$ such that $\partial_i X$ is an outgoing boundary component and $\partial_j Y$ is an incoming boundary component. Let $X \#_{ij} Y$ be the sewn surface obtained by identifying $\partial_i X$ with $\partial_j Y$ using $(\tau_Y^j)^{-1} \circ J \circ \tau_X^i$. Since the choice of $i$ and $j$ is fixed throughout we simply write $X \# Y$ for $X\#_{ij}Y$. Let $\iota_X: X \to X \# Y$ and $\iota_Y: Y \to X \# Y$ be the inclusion maps. Let $g_{X\#Y} = g_X + g_Y$, $n^-_{X\#Y} = n^-_X + n^-_Y - 1$ and $n^+_{X\#Y} = n^+_X + n^+_Y -1$. The Riemann surface $X\#Y$ of type $(g_{X\#Y},n^-_{X\#Y}, n^+_{X\#Y} )$ with boundary trivialization $$\label{tau_sew} {\boldsymbol{\tau}}_{X\#Y} = (\tau_X^1,\ldots,\tau_X^{i-1},\tau_Y^{1},\ldots,\tau_Y^{j-1}, \tau_Y^{j+1},\ldots,\tau_Y^{n_Y}, \tau_X^{i+1},\ldots \tau_X^{n_X})$$ will be considered as the base surface for the Teichmüller space $T^B(X \# Y)$. There are other ways of ordering the boundary components but this issue is not important for our purposes. In conformal field theory the self-sewing operation must be considered. That is, the sewing of two boundary components of a single surface. Everything in this section can be altered without difficulty to cover this situation. We describe three sewing maps: on the level of Beltrami differentials, the level of Teichmüller space, and the level of rigged moduli space. - $\mathcal{S} : L^{\infty}_{(-1,1)}(X)_
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11936, 15, 1292, 253, 20000, 14012, 434, 2245, 12941, 513, 10073, 4135, 275, 18047, 272, 3139, 347, 1907, 30122, 7350, 15, 831, 44013, 84, 13, 281, 247, 3710, 6070, 13, 432, 9933, 7350, 670, 253, 3116, 273, 5628, 25186, 1612, 1108, 253, 594, 14, 8890, 4135, 4322, 15, 49969, 264, 25577, 27, 330, 1285, 282, 329, 15, 596, 4071, 13, 773, 17967, 4135, 11936, 27, 4135, 457, 84, 20000, 14012, 285, 2802, 783, 4605, 273, 14837, 5200, 457, 1806, 596, 4071, 27560, 4306, 17720, 16404, 13, 4397, 2030, 13, 4072, 15, 1876, 4114, 32852, 403, 9269, 327, 1810, 725, 69, 15, 681, 313, 8716, 323, 596, 4071, 481, 1916, 5386, 4834, 432, 253, 30959, 1618, 1511, 530, 4883, 54, 4449, 1311, 5472, 38, 275, 253, 20772, 13590, 285, 4352, 253, 38984, 2234, 15, 1044, 4071, 27560, 4306, 3400, 3569, 1783, 273, 1655, 9933, 3988, 3374, 285, 643, 2561, 1329, 281, 4236, 8548, 15, 596, 4071, 27560, 4306, 369, 15335, 9856, 347, 247, 1355, 2136, 275, 6976, 275, 6752, 15, 187, 187, 15633, 16404, 37150, 27, 2802, 7673, 23340, 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285, 23340, 452, 253, 1682, 1896, 19379, 2493, 15, 688, 8542, 2426, 13, 23340, 588, 3923, 11674, 4116, 15, 733, 369, 253, 954, 6071, 784, 2523, 275, 253, 3332, 3872, 6132, 15, 3808, 275, 6976, 1859, 253, 9735, 13174, 347, 9676, 25991, 17194, 407, 247, 8327, 323, 247, 1805, 1495, 15, 19810, 1859, 253, 27431, 952, 347, 23717, 44774, 8445, 5252, 432, 31222, 896, 275, 616, 1728, 5560, 2246, 15, 2512, 403, 767, 2201, 17339, 1103, 275, 2493, 342, 23340, 326, 253, 747, 2208, 2887, 661, 281, 2953, 15, 10351, 285, 1977, 253, 954, 1774, 2523, 310, 9735, 952, 326, 3523, 275, 8207, 2487, 571, 327, 616, 1039, 281, 6976, 15, 380, 9735, 952, 403, 10932, 407, 25481, 1362, 69, 31290, 273, 5702, 952, 14, 3610, 814, 3129, 398, 15, 41133, 8308, 3506, 12042, 556, 4395, 34304, 281, 4138, 1453, 689, 24636, 322, 710, 46219, 35, 6609, 13, 10098, 407, 253, 2045, 7295, 15, 12128, 8308, 3506, 12042, 5605, 281, 3523, 45686, 273, 594, 14, 8890, 23717, 923, 6426, 407, 8577, 731, 896, 15, 831, 556, 42652, 247, 4016, 48235, 275, 23340, 15, 1284, 247, 11674, 253, 34084, 2208, 1364, 789, 562, 271, 24826, 2097, 273, 15850, 342, 23340, 327, 436, 2523, 15, 510, 1273, 17339, 386, 7350, 253, 13474, 273, 3153, 17645, 281, 23340, 15, 9859, 807, 253, 9543, 33832, 6138, 253, 8913, 273, 3153, 17645, 17228, 281, 23340, 846, 247, 7315, 3306, 552, 2692, 17877, 1971, 275, 2067, 273, 43113, 490, 44530, 19384, 15, 380, 35761, 2208, 858, 417, 7279, 342, 23340, 806, 15, 23340, 24998, 4215, 407, 5590, 1076, 27226, 15, 831, 807, 627, 369, 690, 4016, 9943, 6055, 382, 4884, 1044, 4071, 27560, 4306, 2925, 47, 1852, 7251, 721, 2385, 470, 4148, 1249, 1237, 936, 247, 3668, 1304, 326, 43113, 12946, 651, 4489, 247, 5020, 3894, 275, 247, 5699, 17228, 4660, 285, 1395, 3153, 17228, 715, 23340, 15, 12128, 8308, 34084, 588, 452, 281, 17279, 459, 23340, 670, 253, 13367, 273, 9943, 17228, 6224, 15, 510, 1083, 273, 23340, 310, 47386, 273, 253, 34084, 7295, 457, 84, 3687, 4073, 327, 19379, 2493, 15, 6976, 476, 671, 320, 3264, 281, 3157, 19379, 2493, 342, 1097, 4135, 285, 5427, 15, 733, 310, 16613, 326, 1097, 253, 17147, 285, 5639, 23885, 1705, 432, 6359, 6976, 534, 18275, 327, 253, 5396, 17323, 15, 50, 19, 15, 6976, 556, 3597, 281, 29809, 875, 18496, 285, 5041, 15, 3166, 368, 1158, 352, 310, 1896, 342, 34084, 434, 11518, 3753, 32, 1539, 13753, 947, 27, 309, 10195, 9943, 651, 417, 2997, 253, 26536, 273, 634, 1953, 15, 46689, 3390, 10770, 281, 253, 15285, 3879, 273, 247, 2586, 1649, 14, 5991, 14 ]	can Vietnam expect if your proposal for a SoutheastAsia Martime Treaty became a reality?ANSWER: The Treaty would make all ASEAN states stakeholders in maritime security.There would be more insulation for Vietnam from a unified ASEAN position. ButVietnam would have to bring its baselines in the southeast ('the pregnant lady') intoline with international law, clarify its claims, including making a distinction betweenrocks, low tide elevations and islands.Q5. How long does it take to conclude a "sensitive" treaty like the one youproposed?ANSWER: This is a ten year project at the least. But it could be the focal point forbuilding an ASEAN Political-Security Community.Q6. What are the difficulties ahead?Thayer ConsultancyABN # 65 648 097 1232ANSWER: There are certain maritime disputes that are of long-standing and some Southeast Asian attendees feel they should stay that way. Moving towards a treaty would open old wounds.Q7. What is "Vietnam's proposal for the no first use of force"?ANSWER: Vietnam has presented a proposal for ASEAN and China to agree that none of them will be the first to use force in South China Sea disputes. This would be a pledge by all parties that when an incident occurs they will exercise restraint and not resort to force. This would be an important confidence building measure.Q8. What do you mean by saying that "Vietnam would have to bring its baselines in the southeast ('the pregnant lady') into line with international law"?ANSWER: If you look at a map showing Vietnam's Exclusive Economic Zone (EEZ) there is a noticeable bulge or extension of its southeast coast to take in Tu Chinh (or Wen Anbei in Chinese). This is an excessive claim. Vietnam's Exclusive Economic Zone should be drawn from straight base lines from its coast.The bulge is referred to colloquially in Vietnamese as "the pregnant lady". When Vietnam's draft Law of the Sea went to the Politburo maritime specialists recommended bringing Vietnam's claimed EEZ into accord with international law. This was rejected on the grounds that Vietnam would have to negotiate with China sometime in future and that its excessive EEZ claim was the starting point for negotiations.Suggested citation: Carlyle A. Thayer, South China Sea: Southeast Asia Maritime Treaty,” Thayer Consultancy Background Brief, September 20, 2013. All background briefs are posted on Scribd.com (search for Thayer). To remove yourself from the mailing list type UNSUBSCRIBE in the Subject heading and hit the Reply key.Thayer Consultancy provides political analysis of current regional security issues and other research support to selected clients. Thayer Consultancy was officially registered as a small business in Australia in 2002.Background BriefSouth China Sea: China’s PeaceArk and ‘the String of Pearls’Carlyle A. ThayerSeptember 25, 2013[client name deleted]We are interested in the People’s Liberation Army Navy (PLAN) hospital ship – thePeace Ark -that has docked in Sihanoukville Autonomous Port this week. Interestingtiming, and also an interesting route the ship has been on the past four months; itsalmost a join-the-dots connecting the pearls of China's string.The Chinese military attaché here has been quoted as stating that he has neverheard of the ‘string of pearls’ and that the Peace Ark’s visit was a friendship mission.The Peace Ark stopped in Karachi, Mumbai, Thilawa Port, Chittagong and the rest.We request your assessment of the following:Q1. Why is the Chinese Navy undertaking such an operation?ANSWER: China is taking a leaf out of the U.S. naval engagement play book. The UShospital ship, USNS Mercy (T-AH-19), regularly calls in at regional ports to delivermedical and dental assistance. The US ship is staffed with American doctors andmedical specialists from the region. These visits are for good will and demonstratehumanitarian concern.The Peace Ark performs similar engagement activities for the China. Both the USNSMercy and Peace Ark gain valuable experience in working in local condition,experience that will be useful in future humanitarian assistance and disaster reliefmissions. In return, local medical personnel receive valuable experience in workingalongside foreign counterparts.Q2. What is your assessment of reports about China's interests in all these ports aspart of its "String of Pearls" or strategic bases?ANSWER: The 'string of pearls' is not a term China uses. As China's economic powerhas grown, so too has China's interest in secure sea lines of communication (SLOCs).China needs to call in at ports for to provision and for crew morale. The ports thatChina visits all belong to countries that have close economic relations with China.Contrary to speculation by strategic analysis, China had not used the ports formingthe so-called 'string of pearls' as military bases or for military purposes. The Chinesenavy does, however, make good will port visits, a normal part of naval diplomacy.Thayer ConsultancyABN # 65 648 097 1232Q3. How strong a parallel can be drawn between the route of the "Peace Ark" and the "String of Pearls"?ANSWER: The Peace Ark is visiting ports of friendly nations. This coincides with some of the ports comprising 'the string of pearls'. This is a normal component of naval diplomacy.Q4. What can China gain from such a humanitarian mission? How does it reflect on the disputes in the East and South China seas?ANSWER: China gains operational experience in foreign waters and ports, and knowledge of local medical conditions. China and the medical authorities in local ports each benefit from the exchange of knowledge and experience. Further, China gains in prestige and possibly increased influence in the countries visited.The voyage of the Peace Ark does not have a direct impact on the disputes in the East and South China Sea. But the Peace Ark's port visits do assist China in portraying itself as having humanitarian concerns. This deflects, to a limited extent, from regional concerns about the growth of Chinese naval power – the so-called China threat.Suggested citation: Carlyle A. Thayer, “South China Sea: China’s Peace Ark and ‘the String of Pearls’,” Thayer Consultancy Background Brief, September 25, 2013. All background briefs are posted on Scribd.com (search for Thayer). To remove yourself from the mailing list type UNSUBSCRIBE in the Subject heading and hit the Reply key.Thayer Consultancy provides political analysis of current regional security issues and other research support to selected clients. Thayer Consultancy was officially registered as a small business in Australia in 2002. Background BriefAustralia: ‘More Indonesia, LessGeneva’ – the New GovernmentCarlyle A. ThayerSeptember 24, 2013[client name deleted]We request your assessment of the following:Q 1. The new Australian Prime Minister, Tony Abbott, has suggested ‘moreIndonesia, less Europe’. What are the implications for Australia’s future diplomacy?ANSWER: The Abbott Government has moved quickly to align policy on foreignaffairs, defence, and economic, trade and aid issue. Prime Minister Abbott hasannounced he will give priority to visiting regional states – Indonesia, China, Japanand South Korea - before going to Washington and London.Indonesia is an emerging power whose economy is expected to overtake that ofAustralia in the decades to come. Indonesia is located to Australia’s immediatenorth and is Australia’s second closest neighbor after Papua New Guinea. It isimperative that Australia and Indonesia have the best possible bilateral relations.In practical terms, Indonesia will command priority attention. It was the mostcontentious issue in the recent national election. Some in Australia view the boatpeople as illegal migrants motivated by a desire for a better life. Others view theboat people as asylum seekers seeking safety from persecution back in their homecountries.There are two major irritants in relations with Indonesia that the new governmentseeks to address. Far and away the most important issue is boat people that stop inIndonesia on their way to Australia. The boat people are organized by criminalsyndicates of professional people-smugglers.Prime Minister Abbot has moved swiftly to assert control over Operation SovereignBorders, launched by the previous Government. Prime Minister Abbot wants to stopboats of so-called asylum seeker by turning them back. This has provoked a negativereaction in Indonesia. As a priority the Abbott government must work out anacceptable means of cooperation with Indonesia on this issue.The second irritant concerns the export of live beef to Indonesia. Last year the LaborGovernment announced the ban of live beef cattle to Indonesia after a televisiondocumentary showed cruel treatment in several of Indonesian abattoirs. TheAustralian government did not consult with Indonesia first. Indonesia retaliated byhalting imports. This year there was some negative Australian protectionist reactionThayer ConsultancyABN # 65 648 097 1232to a news report that Indonesian investors would buy a majority share in a huge cattle station and import live cattle into Indonesia. Prime Minister Abbott will have to reassure Indonesia about the reliability of Australian cattle sales.The case of Indonesia is illustrative of the Abbott Government’s greater stress on bilateral relations. Australia can also be expected to improve bilateral relations with both China and India. It is notable that both the defence and foreign ministers come from Western Australia which borders on the Indian Ocean.Q2. Australia has tried to hedge between Beijing and Washington. Do you think it is possible with Abbott's conservative nature?ANSWER: IMany Australian would not accept the premise of your question. Hedging refers to the strategic behavior of a country vis-à-
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755, 512, 776, 10556, 347, 3517, 347, 597, 1472, 4439, 15, 3944, 1358, 1087, 3800, 86, 15, 681, 16, 9188, 484, 187, 20865, 2604, 3800, 81, 7366, 327, 634, 13971, 390, 10469, 2, 596, 35314, 273, 4973, 285, 5441, 387, 634, 48803, 15, 187, 40887, 27, 3944, 1358, 77 ]	The big engine on the plane would then propel it through air for several minutes. For the complete script, visit https://www.prageru.com/videos/why-private-investment-works-govt-investment-doesnt 6:18 Business plan of 2 crore with 30% subsidy by poultry depart Business plan of 2 crore with 30% subsidy by poultry depart Business plan of 2 crore with 30% subsidy by poultry depart published on 14 august 2017 in this video you can know about poultry schemes. the project cost is around 2 crore rupees and government providing 30 % subsidy. this scheme is for all indian and foreign countries peoples. to know more about it pls visit www.animalhusb.up.nic.in disclaimer this is not a promotional or paid video. it is only for education purpose and make awareness about govt. schemes. channel doesn't guarantee any income or profit from any crop or business idea. before choosing any plans who told in channels video please consult with any expert first because I am not an expert. information providing carefully but may be possibility of mistake . 3:30 Sir Humphrey and Jim Hacker discuss art subsidies Sir Humphrey and Jim Hacker discuss art subsidies Sir Humphrey and Jim Hacker discuss art subsidies Subsidy withdrawals and tax hikes push up prices (23 Jan 2018) LEADIN: The Jordanian government has announced new economic measures to generate hundreds of millions of dollars in revenue in 2018. But there are fears that scrapping subsidies and raising taxes will push more people into poverty. STORYLINE: There's plenty on sale in Amman's downtown market. But shoppers are braced for price rises. The Jordanian government has announced new economic measures which lift subsidies and cancel sales tax exemptions on a range of goods. Today (17 January), the tax on carbonated drinks is rising by 10 to 20 percent, Octane 95 and 98 gasoline by 30 percent and packets of cigarettes will cost an extra 0.20 Jordanian dinars (0.3 US dollars). From 1 February, the bread subsidy will also be lifted. Furthermore, the government is imposing charges of 500 to 1,500 dinars (700 to 2,100 US dollars) on imported cars, depending on their weight, while vehicle ownership transfer fess will be reduced by 30 dinars to 200. According to the cabinet, the total revenue expected from these measures will amount to 540 million Jordanian dinars (760 million US dollars). But analysts warn of serious consequences for citizens. "They will face more pressure to decrease expenses, and to reduce trade and economic activities," says economic analyst Hossam Ayyash. He says there could be an "increase of poverty" which will lead to problems with "civil and social peace". The Jordanian government has set aside funds to help the poorest cope with price rises. To qualify for the subsidy, a household's annual income must be less than 12,000 dinars (16,900 US dollars). For individuals, the limit is 6,000 dinars. So far, 230,000 families have signed up for the assistance. Beneficiaries of this National Aid Fund, will receive a cash subsidy of 33 dinars, while children of Jordanian women married to non-Jordanians and Gazans living in the kingdom will receive a subsidy of 27 dinars, if eligible. The government said that 6.2 million Jordanians will benefit from the cash support. But Amman resident Hiba Dobaoud says everyone is feeling the financial squeeze from the economic measures. "All the people are suffering, all the people are complaining, no one is happy, the effect: everyone is angry," she says. "Before we used to say that no one dies from starvation, but unfortunately now people will die from starvation." The sale tax on essential commodities will remain unchanged. Staples goods such as rice, sugar, flour, bulgur, cooking oil, meat, chicken, fish, fresh and powdered milk, eggs and tea will not see any hike in taxation. Goods such as school supplies, orthopaedic devices, sensory assistance equipment, pesticides, fertilisers and veterinary medicines will not see a rise in taxation either. The government also decided to include all senior citizens above 60-years-old in the health care insurance system and to raise the minimum wage from 190 to 200 dinars. These measures were taken as part of a larger governmental fiscal and economic reform to secure financial stability and stimulate the country's economic growth. You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/86fb76d40006b565c8b98b7d776d0e9f Find out more about AP Archive: http://www.aparchive.com/HowWeWork Buy Webcam I used for this video : https://goo.gl/3nrzy9 Buy Microphone I used for this video : https://goo.gl/jhgJeD Loan to BuildCold Storage \| Get upto 50% Subsidy on Cold Storage \| SBI Cold Storage Loan Link to NHB site : http://nhb.gov.in/coldstorage_scheme_guideline.aspx?enc=3ZOO8K5CzcdC/Yq6HcdIxGnFC+VjFQvFstMfkdm4FxM= 7:11 Fisheries Economics & Policy: Subsidies and Taxes Fisheries Economics & Policy: Subsidies and Taxes Fisheries Economics & Policy: Subsidies and Taxes This video is a part of Conservation Strategy Fund's collection of environmental economic lessons and was made possible thanks to the support of the Gordon and Betty Moore Foundation and the Marcia BradyTuckerFoundation. This series is for individuals who want to learn - or review - the basic economics of conservation. This video looks at subsidies and taxes in the fishery industry and how it effects the fisherman's incentives. The Fisheries Economics & Policy series will cover management strategies to preserve fishing in the long term and will include concepts such as open access, common pool resources, tragedy of the commons, maximum economic yield, taxes and subsidies, reducing effort, territorial use rights, transferable quotas and externalities. To follow this series, subscribe to our YouTube channel. For more information on these and other trainings from Conservation Strategy Fund, check out: http://www.conservation-strategy.org/ For copyright information on all sound effects, see http://www.conservation-strategy.org/en/page/csf-economic-video-lessons-sound-references subsidy fund (majaa drama) Public Housing Operating Fund Subsidy This presentation covers the 2014 Public Housing Operating Fund program funding process. An overview will be provided of the guidance notice, "Public Housing Operating Subsidy Eligibility Calculations for Calendar Year 2014." Additionally, an description of highlights and changes to the funding data collection process will be discussed. Agenda: I. Introduction and Overview of Presentation II. Highlights of Processing Notice for 2014 III. 2014 Operating Fund Subsidy Process published: 16 Aug 2013 Subsidies Explained in One Minute A one-minute video which explains what a subsidy is and refers to situations in which subsidies benefit society as a whole as well as to situations in which using them isn't exactly fair. Please like, comment and subscribe if you've enjoyed the video. To support the channel, give me a minute (see what I did there?) of your time by visiting OneMinuteEconomics.com and reading my message. Learn about interest subsidy on home loan or Home Loan Subsidy in this video. To give a boost to the mission of 'Housing for All by 2022' and also address the urban poor's housing requirement, the Pradhan Mantri Awas Yojana (PMAY) is being reworked. Of the four verticals of the scheme, 'Promotion of affordable housing for weaker section through credit linked subsidy' is the one that would appeal to the urbanites the most. There are two important changes being made to the scheme. First, while the existing guidelines are aimed at the economically weaker section (EWS) and the lower income group (LIG) category, earning Rs 3 lakh and Rs 6 lakh per annum respectively, two new subsidy slabs (yet to be notified) will bring in people earning up to Rs 12 lakh and Rs 18 lakh per annum into the fold... published: 17 Feb 2017 Why Private Investment Works & Govt. Investment Doesn't From transportation to energy, and everything in between, should the government invest money in as many promising projects as possible? Or would that actually doom many of those ventures to failure? Burt Folsom, historian and professor at Hillsdale College, answers those questions by drawing on the fascinating history of the race to build America's railroads and airplanes. Donate today to PragerU! http://l.prageru.com/2ylo1Yt Joining PragerU is free! Sign up now to get all our videos as soon as they're released. http://prageru.com/signup Download Pragerpedia on your iPhone or Android! Thousands of sources and facts at your fingertips. iPhone: http://l
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15, 13168, 352, 434, 1512, 1199, 285, 309, 452, 281, 2242, 619 ]	The impressive architecture did nothing to alleviate the stark quality of life, however. The streets were crowded, fear hung heavy. We often didn't have enough food, and it was the same food all the time. Plus, there were long lines out of each store. I waited with my parents, my sisters, for hours in line, it seemed like every day, and sometimes we'd get to the head of the line and there would be no more bread, or dumplings, or chicken, or whatever we had been waiting for. There were many things going on that I didn't understand. My parents' friends—other professors, artists, writers, musicians, doctors, scientists—were over all the time. They brought the food they had: chicken soup, potato cakes, Olivier salad, lamb dumplings, pickles, sauerkraut, braised cabbage, rye bread, sweet beets. My mother added a spice here, salt there, and somehow made it better. Everyone said so. They talked and laughed and argued around our wood table. And they whispered. "Hush ... quiet ... let me tell you, tell no one ... we need higher wages ... voting ... free elections ... religious freedom ... you must be careful, you must stop talking so much, Alexei ... You, too, Svetlana ... the time is not right for protesting ... still dangerous ... don't trust the government ... you are being watched ... they are listening ... the newspapers, simply an extension of the government ... propaganda on television, always they lie to us ... it's not safe for us ... no one knows what happened to Professor Popov ... to the priest ... to his brother ..." We were told, my sisters and I, not to talk about what we heard around that table. Our parents were, officially, members of the Communist Party. It was be a member or live a life of destitution with few job or educational opportunities. But we were secret Christians. In the Communist Party there was no God, no Jesus, no faith, no Christianity allowed. Had anyone known, my parents would have lost their jobs at the university. We would have been moved out of our apartment. My parents would have been able to find only low-paying jobs in a factory, if that. They might have lost custody of us or been sent to an insane asylum. Schools were state run and promoted and taught atheism. There were Russian Orthodox churches, more steeped in tradition, song, ritual, and liturgy, than God. In fact the KGB had infiltrated the Russian Orthodox church. They pretended to be priests and took confession. The Communist Party had demolished or closed thousands of mosques, temples, and churches over the years. We held church services in our home, with my uncles and their families. My mother's parents, Lada and Anatoly, came, as did my father's parents, Konstantin and Ekaterina, all loving people. My grandparents had known each other for decades. As kids, Valeria, Elvira, and I could smell fear around our family's wood table, as well as our mother's sugar-sprinkled pancakes. We could smell people's pervading sense of distrust and hatred toward the government, alongside her baked cinnamon apples. It was a government steeped in corruption, cronyism, spying, paranoia, and violence. Suspicion and obsession with possible dissidents ran high. The television was used for propaganda, the press controlled. The KGB peered into everyone's lives, and chased down and jailed without justice. The economy was stagnating, the government owned everything, the wages were pathetic, and a battle waged each day to buy enough food. Moscow, along with the rest of the Soviet Union, was suffocating and suffering. Life was too hard. But I was a child. I had loving parents who protected me from all they could. My mother and grandmothers taught my sisters and me to cook and sew. We loved to sit with them and sew small pillows using scraps of silk, cotton, even burlap. We lined them with rickrack, lace, or ruffled edges, or we embroidered flowers. We were taught to make our stitches precise, tight, and to use different stitches for different designs. Plus, I had my sisters who I could now and then hear in my head through my widow's peak, the Sabonis gift coming down the generation to me. We had friends. We played outside, bundled in coats. We went to school in uniform, with strict teachers, and we were called Oktyabrenok—October children, in reference to the revolution in October 1917. We were to behave well and study hard and memorize the party lines and songs and when we were older, we could become Young Pioneers, and wear the red scarf of the Communist Party. We did what they told us to do. We tried to ignore that tingling, black, confusing shadow that swirled around us, the hushed voices, the unexplained tears from our mother, and our father's tight face. We let it flow over our small shoulders. Then it all changed. * * * On Sunday I went over to my parents' home for dinner. My mother was babysitting Ailani and Koa because Valerie had work to do for her upcoming trial and Kai had a late shift. She was outside playing with Koa, who was dressed as a white monster, while Ailani and I cut out sugar cookies on the train station table. Ailani is in fifth grade. She has long black hair and likes to talk to her mother about crime and court proceedings. She said that school was sometimes "boring" and that she got in trouble when she made a speech recently. "Oh, uh." I could hardly wait to hear the topic. "What kind of trouble?" Ailani's forehead furrowed as she pressed the rolling pin down on the dough. "Not bad trouble. The teacher, Mrs. Phillips, said we all had to stand and talk for one minute. A lot of the kids were scared to be up in front of the class. Like they were afraid of getting bullied or something. I wasn't scared, because I knew what I was going to talk about." "Which was?" "Defensive wounds." Oh, my Lord. "A fascinating topic for a fifth grader." "Yes!" She grinned at me and picked up a flower cookie cutter. "You get it, Aunt Toni, I knew you would. You know what defensive wounds are, right?" I sure did. "I also told the whole class how to defend themselves against a kidnapper—poke out his eyes, bite his hand, smash his face up, stomp on his inner foot, scream your head off. I showed them how to put their weight on their left foot and bring their right foot up superhard into the man's nuts, and all the kids practiced kicking a kidnapper in the privates and poking out his eyes and then I had crime photos that I ... uh ... I ... uh ... borrowed from Mom ..." "Like for props?" "Yes!" Way to go, Aunt Toni! Ailani smiled. Then she frowned. "That's when I got into trouble. The teacher said the photos weren't appropriate. I hate that word: appropriate. But I said you don't want to end up dead like this, and the teacher said no more photos. Some of the kids said they were scared, and a boy started to cry." Whew. Well, that's our Ailani. I picked up a cookie cutter. It was a four-leaf clover. "Then I wanted to talk to the kids about how to get out of the trunk of a car if they got kidnapped, but the teacher said I had run out of time. She looked kinda tired." Ailani's face was confounded. She frowned, then she smiled. "But I think I'm getting an A because it's important to know about defensive wounds and how to escape from kidnappers, right?" I hardly knew what to say. My mother opened the door to the backyard, and Koa toddled in. "Hey, Koa!" Ailani bent down and hugged Koa the monster, then said, "He tried to eat my lizard today." "You tried to eat a lizard today, Koa?" I clamped my lips together and tried not to laugh. He smiled at me, not a lot of teeth. "I eat lizard." I brushed the hair back from his cowlick. "No, don't. They don't taste good." "Taste good." He giggled. "You need a lid that he can't lift off the lizard aquarium, Ailani." "I know. Mom's getting it." "If you don't, Mr. Grins here is going to eat him for lunch." "Brass knuckles," she said, rolling out more cookie dough. "What?" "The lizard's name is Brass Knuckles. You know. The weapon." "Yes, I know." "And I named my new goldfish, too." "I can hardly wait to hear their names." "Nunchucks and You're Arrested." "You have a lot going on in your head, don't you?" "Yes, I do. Sometimes it's too much and I have to lay my
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Cal.Rptr. 243, 246 (1979) (upholding statute). See also Mass.Gen.Laws Ann. ch. 229, 2 (West Cum.Supp.1980) (railroad not liable in wrongful death for negligence where decedent violated rules of carrier). [2] It is important to keep in mind that ad hoc application of 339 is not equivalent to evaluating child trespasser cases under the standard of "reasonable care to be exercised under all the circumstances," Blumenthal v. Cairo Hotel Corp., D.C.App., 256 A.2d 400, 402 (1969), which this court applies to invitees. See D.C. Transit System, Inc. v. Carney, D.C.App., 254 A.2d 402 (1969). Because of Firfer v. United States, 93 U.S.App.D.C. 216, 219, 208 F.2d 524, 528 (1953), there is a presumption that a trespasser assumes the risk of coming onto the property. That presumption, of course, is conclusive as to an adult, whereas it is rebuttable by a child. A child, however, has the burden to prove under 339(c) that he did not appreciate (and thus assume) the risk in coming onto the property. Beard, supra, 4 Cal.App.3d at 136, 84 Cal.Rptr. at 454. Similarly, the child has the burden under 339(d) and (e) to prove the feasibility of eliminating the danger or otherwise protecting children. Id. Accordingly, even though a child trespasser is not automatically barred from recovery, he must, because of Firfer, supra, carry a burden of proof which an invitee would not. The situation would be different, of course, if we were to abandon Firfer, supra, in favor of a single standard of reasonable care under the circumstances. See Blumenthal, supra at 402; Carney, supra, at 403; Smith v. Arbaugh's Restaurant, Inc., 152 U.S.App.D.C. 86, 96, 469 F.2d 97, 107 (1972), cert. denied, 412 U.S. 939, 93 S.Ct. 2774, 37 L.Ed.2d 399 (1973); Rowland v. Christian, 69 Cal.2d 108, 117, 70 Cal.Rptr. 97, 104, 443 P.2d 561, 568 (1968) (en banc); Mile High Fence Co. v. Radovich, 175 Colo. 537, 548, 489 P.2d 308, 314 (1971) (en banc); Pickard v. City & County of Honolulu, 51 Haw. 134, 135, 452 P.2d 445, 446 (1969); Ouellette v. Blanchard, 116 N.H. 552, 557, 364 A.2d 631, 634 (1976); Basso v. Miller, 40 N.Y.2d 233, 241, 386 N.Y.S.2d 564-568, 352 N.E.2d 868, 872 (1976); Mariorenzi v. Joseph DiPonte, Inc., 114 R.I. 294, 307, 333 A.2d 127, 133 (1975). See generally Comment, The Common Law Tort Liability of Owners and Occupiers of Land: A Trap for the Unwary, 36 Md.L.Rev. 816 (1977). I am reluctant to reconsider Firfer, supra, until we are presented a more typical case, perhaps involving an adult trespasser. See Soule v. Massachusetts Electric Co., Mass., 390 N.E.2d 716, 721 (1979). [3] Penn Central's situation is different. I would affirm the grant of summary judgment. Appellants did not file a Rule 12-I(k) statement controverting Penn Central's statement of material facts or setting forth any other genuine issue of material fact. It is therefore undisputed that appellant's injury occurred on the B & O right-of-way and was not caused by a Penn Central train. Thus, the only possible basis for Penn Central liability would be a breach of duty to help protect child trespassers against injury from a B & O train (or any other train) on B & O property contiguous to Penn Central tracks where appellant may have been playing. Given six contiguous, parallel tracksÔÇöthree B & O, then three Penn CentralÔÇöit would be logical to conclude that any duty to child trespassers should be the railroads' joint responsibility. Absent a barrier between parallel track properties, it is arguably as foreseeable that a child with easy access to Penn Central tracks will be injured by a B & O train a few yards away as it is that a Penn Central train will strike the child. On the other hand, the law is well established, at least in other contexts, that a possessor of land does not have a duty to protect someone on his property against a dangerous condition on adjacent propertyÔÇöfor example, by fencing. Cousins v. Yaeger, 394 F.Supp. 595, 604-05 (E.D.Pa.1975); Villani v. Wilmington Housing Authority, 48 Del. 450, 453, 106 A.2d 211, 213 (1954); Corcoran v. City of San Mateo, 122 Cal.App.2d 355, 358, 265 P.2d 102, 104 (1953); see Jones v. United States, 241 F.2d 26, 28-29 (4th Cir.1957). A California appellate court, in fact, has acknowledged this rule in the present context, though without much elaboration, noting that a railroad did not have a duty to protect against injury on the nearby track of another. Gutirrez, supra 174 Cal.App.2d at 870-71, 345 P.2d at 328. I would not find such a duty here, for it would require standards especially difficult to formulate and apply. In the first place, assuming a potential joint duty, it is not clear how to define and evaluate whether the two railroads' tracks are physically so close to one another that one railroad could not, as a practical matter, be expected to bear responsibility alone for protecting wayward children against entry. Second, the implications of one railroad's refusing to cooperate are unclear. Third, proximate cause problems would be compounded by the possibility that one railroad would face liability for injury to a child by another railroad on the other's own right-of-way. 411 Mass. 788 (1992) 586 N.E.2d 3 ANN M. SHAHZADE vs. C.J. MABARDY, INC. Supreme Judicial Court of Massachusetts, Middlesex. October 7, 1991. February 13, 1992. Present: LIACOS, C.J., WILKINS, LYNCH, O'CONNOR, & GREANEY, JJ. Richard T. Corbett for the defendant. Richard d'A. Belin for the plaintiff. LIACOS, C.J. This is a personal injury action arising out of an automobile accident involving the plaintiff, Ann M. Shahzade, and an employee of the defendant corporation, 789 C.J. Mabardy, Inc.[1] The case was tried to a jury which returned a verdict for the plaintiff in the amount of $300,000. After a motion for a new trial was denied, the defendant appealed to the Appeals Court. We transferred the case to this court on our own motion. The defendant argues the trial judge failed to conduct an impartial trial, and that he erred in refusing to instruct the jury "on the issue of plaintiff's comparative negligence, both as a result of her sudden stopping of her vehicle and her failure to use a seat belt." We affirm. In November, 1984, the plaintiff was stopped in a line of traffic approaching a stop sign at the intersection of Cross Street and Lake Street in Belmont, when her automobile was hit from behind by a pickup truck owned by the defendant and driven by the defendant's employee, Joseph Murphy. The parties differ slightly in their accounts of the events immediately preceding the accident. The plaintiff testified that she had stopped and waited in the line of traffic before she was hit unexpectedly from behind. Murphy testified that he and the plaintiff both had been stopped in the line of traffic, that the plaintiff proceeded and that he followed, that the plaintiff then stopped "suddenly, unexpected[ly]," and that Murphy did not have enough time to stop. Murphy estimated that he was travelling fifteen miles an hour when he struck the plaintiff's automobile. The plaintiff, who was not wearing a seat belt,[2] was thrown forward in her automobile and her head hit the steering wheel. The plaintiff was shaken but was able to drive her automobile home. Once home, she called a friend to take her to the emergency department at Choate-Symmes Hospital, where she was examined, treated, and released. 790 The next morning the plaintiff noticed that her left eye was red. She made an appointment with an ophthamologist, Dr. Paul Barsam, who determined that the plaintiff had sustained an ocular contusion, or a blow to the eye, which resulted in "edema, or swelling, like a blister" in the back of her left eye. The plaintiff subsequently developed complications in both eyes, including retinal detachment in her right eye. By the time of trial in 1989, the plaintiff had lost 40% of the vision in her right eye. Barsam testified that the
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6803, 1543, 342, 253, 6003, 390, 4292, 665, 9716, 390, 24834, 634, 6803, 1690, 533, 417, 3710, 281 ]	services and accompanying documentation are comprised of "commercial computer software" and "commercial computer software documentation" as such terms are used in 48 C.F.R. 12.212 (SEPT 1995) and are provided to the Government (i) for acquisitions by or on behalf of civilian agencies, consistent with the policy set forth in 48 C.F.R. 12.212; or (ii) for acquisitions by or on behalf of units of the Department of Defense, consistent with the policies set forth in 48 C.F.R. 227.7202-1 (JUN 1995) and 227.7202-3 (JUN 1995). 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13, 4748, 13, 326, 4320, 1025, 1072, 14, 11523, 7875, 275, 253, 1375, 15, 1227, 15341, 251, 388, 3941, 45283, 13, 380, 3666, 6956, 1100, 13106, 187, 187, 1615, 1608, 20338, 9857, 13, 5106, 42971, 187, 187, 1615, 1608, 20338, 9857, 13, 5106 ]	you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * / #ifndef OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ #define OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ /* * @file / / * OMG PSM class declaration / #include <spec/dds/sub/cond/TReadCondition.hpp> // Implementation namespace dds { namespace sub { namespace cond { template <typename DELEGATE> template <typename T> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::DataReader<T>& dr, const dds::sub::status::DataState& status) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(dr, status)) { } template <typename DELEGATE> template <typename T, typename FUN> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::DataReader<T>& dr, const dds::sub::status::DataState& status, const FUN& functor) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(dr, status, functor)) { } template <typename DELEGATE> template <typename FUN> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::AnyDataReader& adr, const dds::sub::status::DataState& status, const FUN& functor) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(adr, status, functor)) { } template <typename DELEGATE> TReadCondition<DELEGATE>::~TReadCondition() { } template <typename DELEGATE> const dds::sub::status::DataState TReadCondition<DELEGATE>::state_filter() const { return this->delegate()->state_filter(); } template <typename DELEGATE> const AnyDataReader& TReadCondition<DELEGATE>::data_reader() const { return this->delegate()->data_reader(); } } } } // End of implementation #endif / OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ */ Former President Barack Obama took a thinly veiled swipe at President Trump in Indonesia Saturday, sounding the alarm about “an aggressive kind of nationalism” and grumbling about the U.S. exit from the Paris climate agreement. Obama, in a trip to his childhood home of Jakarta where he lived for four years as a boy, did not mention Trump by name but pushed back against those movements that put the national interest first. “We start seeing a rise in sectarian politics, we start seeing a rise in an aggressive kind of nationalism, we start seeing both in developed and developing countries an increased resentment about minority groups and the bad treatment of people who don’t look like us or practice the same faith as us,” he said according to the Hill. Former presidents typically do not wade into politics so quickly after they leave office, and usually stay out of the limelight so as not to step on the feet of their successor. President George W. Bush most notably went dark until well into Obama’s presidency — despite Obama frequently putting the blame of a sluggish economy at Bush’s feet. But this is the latest of a number of instances in which Obama has sought to place his footprint on the American political debate. Obama also warned that without tolerance and respect for others, then progress will dwindle in politics. “What we will see is more and more people arguing against democracy, we will see more and more people who are looking to restrict freedom of the press, and we’ll see more intolerance, more tribal divisions, more ethnic divisions, and religious divisions and more violence,” he said. According to the Hill, Obama also blasted “the temporary absence of American leadership” on climate change — a reference to the Paris climate agreement, to which Obama submitted the U.S. Trump announced last month that the U.S. would quit the deal, triggering howls of horror from liberals worldwide. “In Paris, we came together around the most ambitious agreement in history to fight climate change,” he told the audience. Earlier that day, Obama was asked about the climate deal and appeared to suggest that America may not leave the controversial climate deal after all, and bragged about how he “locked in” certain rules. “First of all, I think it’s important that even though the current U.S. administration has signaled it is going to pull out, technically it’s not out yet,” he said, according to the Guardian. “Point two is that many of the changes that we locked in during my administration continue.” Adam Shaw is a politics reporter for Breitbart News based in New York. Follow Adam on Twitter: @AdamShawNYProperty Details Property Location When you stay at El Monte Sagrado Living Resort & Spa in Taos, you'll be near the airport, within a 10-minute walk of Kit Carson Home and Museum and D.H. Lawrence Ranch. This 4-star resort is 0.5 mi (0.8 km) from Taos Center for the Arts and 0.5 mi (0.9 km) from Henningsen Fine Arts. Rooms Treat yourself to a stay in one of the 84 guestrooms, featuring fireplaces and flat-screen televisions. Your pillowtop bed comes with premium bedding. Rooms have private balconies. Wired and wireless Internet access is complimentary, while video-game consoles and satellite programming provide entertainment. Amenities Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. A spa tub and a steam room offer a relaxing way to wind down after a day on the slopes. Additional amenities at this resort include complimentary wireless Internet access, concierge services, and ski storage. Dining Grab a bite at The Gardens, one of the resort's 2 restaurants, or stay in and take advantage of the room service (during limited hours). Quench your thirst with your favorite drink at the bar/lounge. Full breakfasts are available for a fee. Business, Other Amenities Featured amenities include a 24-hour business center, limo/town car service, and express check-out. Planning an event in Taos? This resort has facilities measuring 5955 square feet (553 square meters), including conference space. Free valet parking is available onsite. Property Policies Extra-person charges may apply and vary depending on property policy. Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges. Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed. No onsite parking is available. Important Information Please note, there is important information about this property to know before you arrive. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation. Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section). You'll be asked to pay the following charges at the property: Resort fee: USD 25.00 per accommodation, per night The resort fee includes: Pool access Fitness center access Shuttle service Business center/computer access Internet access In-room safe In-room coffee Valet parking Parking Additional inclusions We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book. The following fees and deposits are charged by the property at time of service, check-in, or check-out. Breakfast fee: between USD 10 and USD 25 per person (approximately) Pet fee: USD 50 per accommodation, per day Rollaway bed fee: USD 25.00 per stay The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.Kate, right, and Trish Varnum of Cedar Rapid. Their case is behind the Iowa Supreme Court ruling on April 3, 2009, that legalized same-sex marriage in the state. / Bryon Houlgrave, The Des Moines Register by Sharyn Jackson, USA TODAY by Sharyn Jackson, USA
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659, 2287, 1219, 531, 27, 380, 11793, 16061, 273, 4033, 2191, 13625, 64, 313, 21556, 13254, 27, 418, 5265, 1763 ]	ler, schenkt mir Eure Gunst":_ Max Schmeling, _Erinnerungen,_ revised and amended edition (Frankfurt a.M. and Berlin: Ullstein, 1995), p. 87. "swimming after the dollar": _Box-Sport,_ May 22,1928. "Joe Jacobs gave 'em": _Washington Post,_ May 2,1940. "If all the newspaper copy": _New York Mirror,_ June 26,1936. "It's too darned quiet": _The Boxing News,_ June 1936. "my little wife": _New York Mirror,_ October 7,1940. "Why do guys have to sleep at all?" _Ring,_ July 1940. "a New York sidewalk boy": _New York World-Telegram,_ April 26,1940. "If you hang me": _New York Sun,_ April 26,1940. "You take the big tree": _New York World-Telegram,_ June 8,1933. "triple pneumonia": _Collier's,_ July 1,1939. "The Black Uhlan of the Rhine": Schmeling, _Erinnerungen,_ p. 128. Frank Graham, among others, attributed the nickname to Damon Runyon, _New York Journal-American,_ February 6,1961. "Dempsey! Dempsey!": _Box-Sport,_ January 7,1929. "all Berlin was frantic with joy": _New York Times,_ June 29,1929. "He is quiet, modest": _New York Sun,_ June 7,1930. "an insolence": _New York World-Telegram,_ May 29,1941. "punch harder than": _Forverts,_ June 22,1930. "the fighting son of the Fatherland": _New York Daily News,_ June 13,1930. "the man on whom every American": Ibid. "paralyzed": _New York Times,_ June 14,1930. "Stay down, you idiot!": _Forverts,_ April 27,1940. "a screaming, dancing midge": _Outlook and Independent,_ July 2,1930. "You're the champion, Max!" _New York Mirror,_ June 13,1930. "as though an armored truck": _New York Journal-American,_ April 25,1940. "a severe blow": Associated Press, April 13,1930. "From the bottom of my heart": _New York Daily News,_ June 13,1930. "If anyone won": _Outlook and Independent,_ July 2,1930. "You know, that _Yacobs": New York Daily News,_ June 14,1930. "I'm sure it helped me": _Forverts,_ June 22,1930. "this unpleasant, loud-mouthed": _Angriff,_ November 25,1930. "We're on our way": _Der Abend,_ quoted in _New York World,_ June 14,1930. "a concert of boos": Rolf Nürnberg, _Die Geschichte einer Karriere_ (Berlin: Grossberliner Druckerei für Presse und Buchverlag, 1932), p. 148. "a disgrace to German": _New York Times,_ January 8,1931. "mean, impertinent, incompetent Jew": _Angriff,_ January 8,1931. "Ruthlessness was the": Nürnberg, _Die Geschichte einer Karriere,_ p. 13. "He was robbed": _New York Evening Post,_ June 22, 1932; "He was jobbed": _New York American,_ June 22,1932; "We were robbed": _New York Graphic,_ June 22,1932. "The great Sharkey-Schmeling": _New York Daily News,_ June 23,1932. "someone closing a deal": _New York World-Telegram,_ June 23,1932. "German boy of the future": Hajo Bernett, _Nationalsozialistische Leibeserziehung_ (Schorndorf bei Stuttgart: Karl Hofmann, 1966), p. 25. "There is no sport that cultivates": Adolf Hitler, _Mein Kampf_ (Munich: F. Eher Nachf., 1933), p. 453. "a German revolution of pimps, deserters": Ibid., p. 453. "the high cheek bones of an Indian": _New York Mirror,_ December 4,1937. "incapable of performing even a single knee-bend": _Angriff,_ November 6,1930. "a man from whom even his own kind turn away": Ibid., January 7,1931. "mean," "impertinent," "incompetent" Jew: Ibid., January 8,1931. "grubby" Jacobs; "spruced-up numbskull and toady": Ibid., January 7,1931. "Finally, Finally!": Ibid., April 4,1933. "Jewish capital or Jewish persons": _Box-Sport,_ April 3,1933. "a defensive action against": _Angriff,_ April 4,1933. "whatever else these blood-suckers call themselves": Ibid. "a clique of corrupt": _Box-Sport,_ April 3,1933. "Jewish big-wigs and corrupt exploiters": Ibid. "giving the cold shoulder": Ibid., April 18,1933. "If anyone over there": Schmeling, _Erinnerungen,_ p. 263. "exaggerated and untruthful": _Boxing,_ April 5,1933. "It would be paradoxical": _LAuto,_ April 2,1933. "The fact that the new, great leader of the German people": _Box-Sport,_ October 24, 1933. "the decrepit medievalism": _New York Mirror,_ March 27,1933. "We all know what would happen": _New York American,_ April 14,1933. "shame the Nazis by lying down": _New York World-Telegram,_ April 17,1933. "Delancey Street dandy": _New York Daily News,_ March 22,1935. "There are many Hebrews here": _Montreal Herald,_ April 14,1933. "He dodges embarrassing questions": _New York Sun,_ April 15,1933. "What conditions?": _New York Evening Post,_ April 14,1933. "I haff never seen Yermany": _New York Daily News,_ April 18,1933. "my friend Joe": _New York World-Telegram,_ April 14,1933. "the most popular person in Germany": _New York Evening Post,_ April 14,1933. "I tell you this—Germany is improving": _New York American,_ April 15,1933. "prices on the Boerse": _New York World-Telegram,_ April 14,1933. not to be "silly" about the man: _New York Evening Post,_ April 14,1933. "Were I to meet Baer in Germany": _New York Mirror,_ April 15,1933. MAX SCHMELING SAYS GERMANY IS NOT CRUEL TO JEWISH FOLKS: The paper is probably the _Plain Speaker_ of Hazelton, Pennsylvania. "100 percent Hitlerist": _Moment_ (Warsaw), June 11,1933. "Schmeling pulled himself": _Box-Sport,_ May 1,1933. "When I told them about the reception": Schmeling, _Erinnerungen,_ p. 266. ## Chapter Two: A Regime's Embrace "stand in defense, with clenched fist": _Box-Sport,_ April 25,1933. "to follow in his path": Ibid., May 1,1933. "The movement to make Max Schmeling suffer": _New York Mirror,_ April 21,1933. "none is so blind": Ibid., April 25,1933. "no more of a Jew-hater": Ibid., April 26,1933. "has to return to Germany some time": Ibid., April 27,1933. "I'll try to make [Max Baer] think you're to blame": _Pittsburgh Post-Gazette,_ April 18, 1933. "Shall I give them a political talk?": _Pittsburgh Press,_ April 17,1933. "We simply ignore it": _New York Times,_ April 26,1933. "Well, that's awfully nice of him": _New York Mirror,_ April 26,1933. "malicious, vitriolic, and imbecilic": _Ring,_ June 1933. "at that moment... a friend, or a lover, or something": _New York Journal-American,_ March 3,1965. "I've got a million-dollar body": _New York Times,_ November 25,1959. "Hey, Barney": Barney Ross, _No Man Stands Alone: The True Story of Barney Ross_ (Philadelphia: Lippinc
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2608, 2402, 426, 2876, 15, 16801, 28, 4888, 988, 186, 5302, 313, 1838, 682, 15283, 9414, 426, 2752, 27683, 19570, 15, 31141, 15283, 9, 17158, 186, 13457, 2776, 15, 3633, 5703, 13457, 2776, 5715, 17158, 186, 11296, 12094, 15, 21395, 5715, 17158, 186, 274, 18246, 1228, 11459, 186, 92, 17158, 186, 338, 313, 28011, 15, 5703, 6649, 17158, 186, 92, 28778, 186, 4537, 2402, 426, 9414, 9855, 2402, 37594, 21395, 1874, 17158, 186, 94, 4888, 988, 186, 94, 4888, 988, 186, 2309, 2608, 2402, 28, 7951, 186, 94, 39015, 186, 4387, 4228, 2876, 41977, 9, 565, 2670, 2618, 13, 2876, 16164, 2402, 13, 2876, 9868, 10, 7951, 186, 92, 4888, 988, 186, 2776, 12038, 21512, 12094, 426, 747, 50233, 1874, 11459, 186, 11296, 12094, 15, 33253, 1587, 12995, 9424, 33051, 4888, 988, 186, 11296, 12094, 15, 33253, 1587, 22050, 50276, 2503, 64, 17104, 33051, 4888, 988, 186, 11296, 12094, 15, 33253 ]	Email ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?Email", MySqlDbType.VarChar, 100); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = email.ToLower(); return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams); } public static IDataReader GetSingleUserByLoginName(int siteId, string loginName, bool allowEmailFallback) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT * "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE SiteID = ?SiteID "); if (allowEmailFallback) { sqlCommand.Append("AND "); sqlCommand.Append("("); sqlCommand.Append("LoginName = ?LoginName "); sqlCommand.Append("OR Email = ?LoginName "); sqlCommand.Append(")"); } else { sqlCommand.Append("AND LoginName = ?LoginName "); } sqlCommand.Append(";"); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?LoginName", MySqlDbType.VarChar, 50); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = loginName; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams); } public static IDataReader GetSingleUser(int userId, int siteId) { const string sqlCommand = @" SELECT * FROM mp_Users WHERE UserID = ?UserID AND SiteID = ?SiteID;"; var arParams = new List<MySqlParameter> { new MySqlParameter("?UserID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = userId }, new MySqlParameter("?SiteID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = siteId } }; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand, arParams.ToArray() ); } public static IDataReader GetSingleUser(Guid userGuid, int siteId) { const string sqlCommand = @" SELECT * FROM mp_Users WHERE UserGuid = ?UserGuid AND SiteID = ?SiteID;"; var arParams = new List<MySqlParameter> { new MySqlParameter("?UserGuid", MySqlDbType.VarChar, 36) { Direction = ParameterDirection.Input, Value = userGuid.ToString() }, new MySqlParameter("?SiteID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = siteId } }; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand, arParams.ToArray() ); } public static Guid GetUserGuidFromOpenId( int siteId, string openIdUri) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT UserGuid "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE "); sqlCommand.Append("SiteID = ?SiteID "); sqlCommand.Append("AND OpenIDURI = ?OpenIDURI "); sqlCommand.Append(" ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?OpenIDURI", MySqlDbType.VarChar, 255); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = openIdUri; Guid userGuid = Guid.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userGuid = new Guid(reader["UserGuid"].ToString()); } } return userGuid; } public static Guid GetUserGuidFromWindowsLiveId( int siteId, string windowsLiveId) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT UserGuid "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE "); sqlCommand.Append("SiteID = ?SiteID "); sqlCommand.Append("AND WindowsLiveID = ?WindowsLiveID "); sqlCommand.Append(" ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?WindowsLiveID", MySqlDbType.VarChar, 36); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = windowsLiveId; Guid userGuid = Guid.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userGuid = new Guid(reader["UserGuid"].ToString()); } } return userGuid; } public static string LoginByEmail(int siteId, string email, string password) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT Name "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE Email = ?Email "); sqlCommand.Append("AND SiteID = ?SiteID "); sqlCommand.Append("AND IsDeleted = 0 "); sqlCommand.Append("AND Pwd = ?Password ; "); MySqlParameter[] arParams = new MySqlParameter[3]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?Email", MySqlDbType.VarChar, 100); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = email; arParams[2] = new MySqlParameter("?Password", MySqlDbType.Text); arParams[2].Direction = ParameterDirection.Input; arParams[2].Value = password; string userName = string.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userName = reader["Name"].ToString(); } } return userName; } public static string Login(int siteId, string loginName, string password) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT Name "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append
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4492, 15, 20963, 187 ]	't worry about it. Don't stop. Don't contemplate walking. Defeatism is not allowed. It also makes for poor time. Keep on keeping on. Think of the long-distance lorry driver and how he gets further up the road in a shorter time than the flash-car motorist that is forever pulling over to service stations. Or think of the tortoise and the hare. It is all about keeping going. Don't expect to master the art of hill climbing overnight. But if you keep at it then it will come to you. A: The gradient and length of your hill will influence how you handle it. Generally speaking it is good to maintain your momentum for as long as you can. Standing up is fine if you're intending to power up a short hill. If you're in it for a long slog, it is good to stay seated, put your hands on the flats, breath deeply and keep the upper body as relaxed as possible. Occasionally stand up and mash to break the monotony or force your cadence higher but you'll waste energy if you do it too much. It certainly is possible to be in too low of a gear (especially on a triple like you have). If you're spinning quickly and the steering is slightly wobbly, your gear is too low and you should try something higher and go faster. Rep. Alexandria Ocasio-Cortez (D-NY) suggested expanding the United States’s two party system in an interview Thursday. MSNBC’s Chuck Todd questioned the freshman congresswoman about whether her brand of Democratic socialism can appeal outside of her deep blue New York district, before probing about whether the two-party system reflects the diverse viewpoints of the country. “Do you think it would be helpful for our system if we have four or five parties?” Todd asked. The Democrat agreed. “Four or five, I think that’s fine,” she added. “It sounds like the two major parties, you feel like, don’t serve this well,” Todd followed up. “I think that it’s totally fine to say that a two party system is, especially in this time of gridlock, is sometimes a difficult thing to navigate,” she replied. “It’s a normal thing to say after these years and years and decades of gridlock. Saying, maybe something here is structurally wrong.” “I think it’s a fine conversation to have,” she added. Earlier in the interview, Ocasio-Cortez said she considers herself a capitalist, which she argued can be reconciled with her Democratic socialism. Watch above, via MSNBC. Have a tip we should know? [email protected] Star halfway across the universe was visible to naked eye for 30 secs on Wednesday - alexwg http://news.nationalgeographic.com/news/2008/03/080321-brightest-object.html ====== dhimes Those of you interested in astronomical things may enjoy <http://www.badastronomy.com/> ------ mynameishere [http://en.wikipedia.org/wiki/Gamma_ray_burst#Mass_extinction...](http://en.wikipedia.org/wiki/Gamma_ray_burst#Mass_extinction_on_Earth) ------ trekker7 Wow, this is amazing. Anybody on HN happen to see it? ------ doubleplus Halfway across the visible universe, not the entire universe, which is 90+ billion light years across. 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pm ct, the shape of his assassination, we determine computing machine vigil ceremonies and get back his life principle of violent aim action. Kinsfolk with sentiments across the persuasion compass square measure invited to unify and perceive frequent reach against corruption. We disinherit overpower water parting and usurp propaganda by take shape communities of hold and compassion.College wrestler suspended for homophobic tweets about Michael Sam A Kent State wrestler is in hot water after sending out some offensive tweets about Michael Sam. Kent State sophomore Sam Wheeler used anti-gay language while complaining that Sam, the first openly gay NFL draft prospect, was the only story on SportsCenter on Monday. The university suspended Wheeler indefinitely. Sam announced he is gay on Sunday night. He won SEC Defensive Player of the Year after recording 11.5 sacks for Missouri last season. “We are aware of the insensitive tweets by one of our student athletes,” director of athletics Joel Nielsen said in a statement released by Kent State. “On behalf of Kent State University, we consider these comments to be ignorant and not indicative of the beliefs held by our university community as a whole. This is an educational opportunity for all of our student-athletes.” “As an alum of Kent State University and as Sam’s head coach, I was surprised and offended by what I read on Twitter,” wrestling coach Jim Andrassy said in a statement. “I have spoken to Sam personally, and while he is remorseful, he will be suspended indefinitely while we determine the best course of action moving forward.”Hermansky-Pudlak syndrome Common Name(s) Hermansky-Pudlak syndrome is a multisystem, genetic condition characterized blood platelet dysfunction with prolonged bleeding, visual impairment, and abnormally light coloring of the skin, hair, and eyes (oculocutaneous albinism). Long-term sun exposure greatly increases the risk of skin damage and skin cancers. Some individuals have colitis, kidney failure, and pulmonary fibrosis. Symptoms of pulmonary fibrosis usually appear during the early thirties and rapidly worsen. This condition is inherited in an autosomal recessive fashion. There are eight different types of Hermansky-Pudlak syndrome, which can be distinguished by their signs and symptoms and underlying genetic cause. Types 1 and 4 are the most severe forms. Types 1, 2, and 4 are the only types associated with pulmonary fibrosis. Individuals with type 3, 5, or 6 have the mildest symptoms of all the types. Little is known about the signs, symptoms, and severity of types 7 and 8. To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders. How do you compare to others with this condition? Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives. Advocacy and Support Organizations Condition Specific Organizations Following organizations serve the condition "Hermansky-Pudlak syndrome" for support, advocacy or research. To ensure that people affected by bleeding disorders have the freedom to make choices and seize opportunities To enable people affected by bleeding disorders to better understand and manage their condition or situation. To enable people affected by bleeding disorders to participate in decision making and service delivery. To influence policy and improve services to people with bleeding disorders. General Support Organizations Recommended Apps Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives. Finding the right clinical trial for Hermansky-Pudlak syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity. Scientific Literature Articles from the PubMed Database Research articles describe the outcome of a single study. They are the published results of original research. The terms "Hermansky-Pudlak syndrome" returned 94 free, full-text research articles on human participants. First 3 results: We herein report a case of Hermansky-Pudlak syndrome (HPS) with nonspecific interstitial pneumonia (NSIP). A 58-year-old Japanese woman presented with oculocutaneous albinism and dyspnea on exertion. A high resolution computed tomography scan showed areas of reticular and ground glass ... Reviews from the PubMed Database Review articles summarize what is currently known about a disease. They discuss research previously published by others. The terms "Hermansky-Pudlak syndrome" returned 2 free, full-text review articles on human participants. First 3 results: Hermansky-Pudlak syndrome (HPS) is a rare genetic disorder, the most common complication of which influencing the prognosis is pulmonary fibrosis. In the present report, we describe an autopsy case of a Japanese woman with HPS. The patient was diagnosed at 50 years of age based on ... According to ClinicalTrials.gov there are currently 0 additional "open" studies for "Hermansky-Pudlak syndrome" (open studies are recruiting volunteers) and 7 "Hermansky-Pudlak syndrome" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance: Relief is when you and the right researcher find each other Finding the right clinical trial for Hermansky-Pudlak syndrome can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.Jessica Shipmanis an experienced web developer, software engineer, and WordPress blogger. With the goal of making technology less scary for bloggers and small businesses, Jessica offers a variety of services and helpful free tips. Are you ready to conquer your blogging tech? WORDPRESS HELP & MAINTENANCE With years of experience as a WordPress blogger and web developer, Jessica offers a unique combination of skills to get your blog running seamlessly. FREE TIPS & TRICKS FOR BLOGGERS Subscribe and check back for step by step tutorials for difficult tasks and advice on plugins and tech tools from a seasoned WordPress blogger. NEW E-COURSES COMING SOON! Be the first to know about the launch of brand new e-courses designed to help bloggers and small business owners conquer their tech! CURRENTLY ACCEPTING REQUESTS FOR FREELANCE WORK WHAT I DO CHECK OUT MY SERVICES WordPress Migration & Makeovers Dying to get your blog on WordPress, but overwhelmed with how to do it? Sick of your old theme and ready for an upgrade? I've got you covered with migrations from any other platform, custom makeovers, and even setting up brand new blogs! Troubleshooting & Customization Did you update a plugin and everything broke? Weird error message you can't figure out? Or just have a small feature you want to add? Talk to me and I'll walk you through the fix or get you all set up! Host Maintenance Do you want to transfer to a new host? Can't figure out how to set up custom email addresses? Or just don't have time to handle hosting issues when they happen. Let's talk about host maintenance packages! HTML & CSS Coaching Want to learn HTML & CSS to modify your blog or website on your own? Talk to me about how I can provide one on one tips, training, and even homework assignments to turn you into an HTML pro! Are you ready to boost your blog or business with FREE technical tips? HOW I'M DIFFERENT I CARE ABOUT CUSTOMER SERVICE I have high standards for customer service, which I will absolutely hold myself to. You can expect timely responses and results. I love my clients and they are my top priority! Your happiness is key. I'M A BLOGGER TOO I've been blogging professionally since March 2013, so I know first hand of the joys and struggles of trying to have your blog stand out. Want more proof? You can find me over at www.beaglesandbargains.com. MY GOAL IS TO EMPOWER YOU I value you and your time, so I'm not here to waste it. My goal is super simple. I want bloggers and small business owners to feel more comfortable with web development and technology. DROP ME A LINE Want to learn more? Ready to set sail to a bigger and better blog? Click the button below for my contact form or shoot an email over to [email protected]JavaScript must be enabled in order for you to use this site. However, it seems JavaScript is either disabled or not supported by your browser. Enable JavaScript by changing your browser options, and then try again. These kits are designed to replace incandescent lamps with LED lamps in Exit signs. Each features slim

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Brazil. (Photo by Joe Raedle/Getty Images) less RIO DE JANEIRO, BRAZIL - JUNE 21: German team fans watch their team play against Ghana on the screen setup at the Word Cup FIFA Fan Fest during on Copacabana beach June 21, 2014 in Rio de Janeiro, Brazil. ... more Fans cheer in support of the German national football team near the Brandenburg Gate in Berlin, Germany on June 21, 2014 during the public viewing of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less Fans cheer in support of the German national football team near the Brandenburg Gate in Berlin, Germany on June 21, 2014 during the public viewing of the FIFA World Cup 2014 group G football match Germany vs ... more Photo: AFP/Getty Images Fans cheer in support of the German national football team near the... Photo-6500869.88425 - Houston Chronicle Image 45 of 71 A German fan reacts during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less A German fan reacts during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP ... more Photo: AFP/Getty Images A German fan reacts during the public viewing near the Brandenburg... Photo-6500870.88425 - Houston Chronicle Image 46 of 71 Fans wave the German flag during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. AFP PHOTO / CLEMENS BILAN (Photo credit should read CLEMENS BILAN/AFP/Getty Images) less Fans wave the German flag during the public viewing near the Brandenburg Gate in Berlin, Germany on June 21, 2014 of the FIFA World Cup 2014 group G football match Germany vs Ghana played in Fortaleza, Brazil. ... more Photo: AFP/Getty Images Fans wave the German flag during the public viewing near the... Photo-6500871.88425 - Houston Chronicle Image 47 of 71 BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more BELO HORIZONTE, BRAZIL - JUNE 21: Iran fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Iran fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad ... more BELO HORIZONTE, BRAZIL - JUNE 21: An Argentina fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: An Argentina fan during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more CUIABA, BRAZIL - JUNE 21: A Bosnia-Herzegovin fan shows her colours ahead of the 2014 FIFA World Cup Group F match between Nigeria and Bosnia-Herzegovina at Arena Pantanal on June 21, 2014 in Cuiaba, Brazil. (Photo by Matthew Lewis/Getty Images) less CUIABA, BRAZIL - JUNE 21: A Bosnia-Herzegovin fan shows her colours ahead of the 2014 FIFA World Cup Group F match between Nigeria and Bosnia-Herzegovina at Arena Pantanal on June 21, 2014 in Cuiaba, Brazil. ... more A fan takes a selfie before the start of the Group F football match between Nigeria and Bosnia-Hercegovina at the Pantanal Arena in Cuiaba during the 2014 FIFA World Cup on June 21, 2014. AFP PHOTO / JUAN BARRETO (Photo credit should read JUAN BARRETO/AFP/Getty Images) less A fan takes a selfie before the start of the Group F football match between Nigeria and Bosnia-Hercegovina at the Pantanal Arena in Cuiaba during the 2014 FIFA World Cup on June 21, 2014. AFP PHOTO / JUAN ... more Photo: AFP/Getty Images A fan takes a selfie before the start of the Group F football match... Photo-6500879.88425 - Houston Chronicle Image 54 of 71 BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin Mohammad Jamali/Getty Images) less BELO HORIZONTE, BRAZIL - JUNE 21: Argentina fans during the 2014 FIFA World Cup Brazil Group F match between Argentina and Iran at Estadio Mineirao on June 21, 2014 in Belo Horizonte, Brazil. (Photo by Amin ... more A Russian supporter cheers for her team ahead of the Group H football match between Belgium and Russia at The Maracana Stadium in Rio de Janeiro on June 22, 2014, during the 2014 FIFA World Cup. AFP PHOTO / GABRIEL BOUYS (Photo credit should read GABRIEL BOUYS/AFP/Getty Images) less A Russian supporter cheers for her team ahead of the Group H football match between Belgium and Russia at The Maracana Stadium in Rio de Janeiro on June 22, 2014, during the 2014 FIFA World Cup. AFP PHOTO / ... more Photo: AFP/Getty Images A Russian supporter cheers for her team ahead of the Group H... Photo-6500881.88425 - Houston Chronicle Image 56 of 71 A Belgium's fan poses as she waits for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro during the 2014 FIFA World Cup on June 22, 2014. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images) less A Belgium's fan poses as she waits for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro during the 2014 FIFA World Cup on June 22, 2014. AFP PHOTO / ... more Photo: AFP/Getty Images A Belgium's fan poses as she waits for the start of the Group... Photo-6500882.88425 - Houston Chronicle Image 57 of 71 Belgium's supporters cheer as they wait for the start of the Group H football match between Belgium and Russia at the Maracana Stadium in Rio de Janeiro

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KRAS mutation was found to be associated with the absence of biological and clinical activity for the anti-EGFR antibody treatment. [7, 8, 14] Approximately 30% to 50% of colorectal tumors are known to have a mutated (abnormal) KRAS, indicating that up to 50% of patients with CRC might respond to anti-EGFR antibody therapy. However, 40% to 60% of patients with wild-type KRAS tumors do not respond. [1] In these patients, data suggest that mutated BRAF, which is present in 5% to 10% of tumors, can affect response to these agents. [5, 6, 10] To see complete information on Colorectal Cancer, please go to the main article by clicking here. Previous Next: Clinical Implications of the Genetic Mutations Several phase II/III randomized trials have revealed the favorable impact on survival associated with the administration of one of two currently available anti-EGFR antibodies (cetuximab [Erbitux], panitumumab [Vectibix]) in patients with KRAS wild-type. [7, 8, 9, 10] In July 2012, the indication for cetuximab was updated to specify treatment of KRAS mutation-negative (wild-type), EGFR-expressing, metastatic colorectal cancer as determine by FDA-approved tests (eg, therascreen KRAS RGQ PCR Kit). A careful read of the data from these and other trials clearly demonstrates that patients with mutated KRAS are unlikely to benefit from anti-EGFR antibody therapy. However, it is not clear that patients with KRAS wild-type will definitely respond, only that they have a reasonable opportunity to derive clinical benefit from the therapy. For example, in the panitumumab vs best supportive care trial, there were no responders in the mutated KRAS group randomized to the therapy and only a 17% partial response rate was noted in the KRAS wild-type group. [8] It is unclear to what extent the lack of response in KRAS wild-type patients is due to BRAF mutations, but current data suggest that mutated BRAF confers resistance to anti-EGFR therapy given beyond first-line treatment. A retrospective analysis of 113 patients who received cetuximab or panitumumab demonstrated that none of the KRAS wild-type patients with BRAF mutations responded to therapy, and that none of the responders had BRAF mutations. In addition, BRAF mutant patients showed prolonged progression-free and overall survival compared with BRAF wild-type patients. [5] Similarly, a retrospective pooled analysis of the two phase III cetuximab studies demonstrated that the best treatment outcomes were observed in patients with both KRAS wild-type and BRAF wild-type tumors, but there were too few patients with BRAF mutations to determine whether BRAF mutation status alone could predict response to therapy. [6] Finally, in the cetuximab plus FOLFIRI study, although mutated BRAF was associated with a poor prognosis, it did not independently predict response to treatment. [10] Thus, although results from these and other studies are compelling, there are as yet no prospective data that can definitively determine the role of BRAF status in response to EGFR inhibitor therapy. Based on these observations, it is vital that patients with metastatic CRC who are being considered for treatment with anti-EGFR antibody therapy should be tested for the presence of a KRAS mutation prior to the administration of therapy and that both cetuximab and panitumumab be initiated only in patients with KRAS wild-type. This will ensure that the therapy is not administered to patients who are unlikely to obtain benefit. [17, 18] In fact, NCCN Clinical Practice Guidelines recommend testing for KRAS mutations at the time of diagnosis of stage IV disease so as to better prepare an appropriate management plan in case treatment with an anti-EGFR antibody is later considered. [17] Cetuximab labeling specifies use in CRC KRAS wild-type tumors and panitumumab labeling states use is not recommended for treatment with KRAS mutations. BRAF mutation status should be determined only after KRAS wild-type is detected. [17] Testing for microsatellite instability and mismatch repair lends information for the option to use pembrolizumab for unresectable or metastatic colon cancer that has tested positive for microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) and has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. [12] Previous Next: Testing for the Genetic Mutations Testing for mutations in codons 12 or 13 of the KRAS gene can be performed on formalin-fixed, paraffin-embedded tissue from the primary tumor or a metastasis using a variety of methods. BRAF V600E mutation status is determined via PCR amplification and DNA sequence analysis or allele-specific PCR on formalin-fixed, paraffin-embedded tissue from the primary tumor or a metastasis. Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Genentech; Astra-Zeneca ; Clovis; Tesaro<br/>Received income in an amount equal to or greater than $250 from: Astra-Zeneca; Clovis; Genentech; Tesaro; Celgene<br/>Received consulting fee from Genentech; Received consulting fee from Cellgene; Received consulting fee from Crititech; Received consulting fee from Amgen.Bulldogs plan to use home-course advantage Published 1:00 pm, Friday, September 24, 2010 Photo: Courtesy Photo By Betsy Lewis Image 1of/1 Caption Close Image 1 of 1 Photo: Courtesy Photo By Betsy Lewis Bulldogs plan to use home-course advantage 1 / 1 Back to Gallery Fall golf is more about getting better for the spring than anything else, but after starting off with a third-place finish last week in the Hereford Invitational, the Plainview Bulldogs are looking to make a bit of a statement to some of their new District 3-4A opponents. The Dogs played with Dumas in Hereford, and this week at the Plainview Triangular they are matched up with Randall and Caprock. Head coach Mike Lewis wants his team to think about what their play in this early fall tournament could communicate to their district opponents. "I told them ‘You can set the tone for next spring by playing well now so these guys think Plainview is going to be tough to beat on its home course,' " Lewis said, adding that the Bulldogs will host one of the district tournaments in the spring. The Bulldogs are a young group this year with a couple of freshman on the roster - Thomas Wirth and Matt Jolly - who Lewis said he hopes gain some confidence and experience this fall. "Individually, I want all of them to do the best they can," Lewis said. "But mostly I want them to improve on the things we talk about in practice. Definitely, want them to focus on the short game, but each one of them has strengths and weaknesses." The three veterans on the team - Jacob Rogers, Trent Kinkaid and Tim Gonzales - were able to play in summer tournaments with the freshman and were able to develop a chemistry this summer that Lewis said he thinks will benefit the team. "These older guys knew the freshmen were going to help us out. I don't think they knew they were going to make us better so quick," Lewis said. In Saturday's triangular, Lewis expects his team to post a score near 300. "I'm thinking we should be around 304 or better," Lewis said. "That's a 76 average. They all know they can reach that because they've done it before, but if they shoot that or lower, then we get close to breaking 200." While it is a long time away, Lewis hopes his team can use this opportunity on their home course to develop some confidence for district competition in the spring. "I want the guys to know they have the ability to get to regionals," Lewis said. "Of course, that's way down the road, but if we can have some success early and get some confidence in them, it will be easier in the spring." (Contact Ryan Thurman at 806-296-1355 or [email protected]. Become his fan on Facebook.)The hepatitis C virus (HCV) is an important pathogen that has infected approximately 170 million people worldwide. In spite of extensive efforts, surprisingly little is known about the mechanism by which HCV initiates infection. The lack of vaccine or effective therapy against this virus stresses the urgent need for studies of HCV entry into host cells. HCV is an enveloped virus that enters cells via a clathrin-mediated pathway and releases its nucleocapsid by fusing the viral membrane with an endosomal membrane a process that is promoted by HCV E1 and E2 glycoproteins. The fusion induced by E1E2 is strictly receptor- and low pH-dependent. Not only is the mechanism of this process poorly understood, but even the identity of the fusion protein (E1 vs. E2) has not been established. This is due to the lack of a tractable model system to study HCV fusion. Our working hypothesis is that HCV fusion precedes through at least two major steps - a priming step through interactions with cellular receptors which render E1E2 fusogenic, followed by low pH-dependent fusion. This hypothesis predicts that: (1) low pH pre-treatment in the absence of receptors

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+1)}$ into stack $R$, output $5_{6(j+1)}, 12_{6j},13_{6j}$, move $9_{6(j+1)}$ to stack $R$ to reach the configuration in Fig. \[fig:Premoved2\], which we can sort by Lemma \[lem:can\_sort1\]. If $j=i$ then the remaining input is just $S_i=(14\ 15 \ 11)_{6i}$: move $14_{6i},15_{6i}$ to stack $R$, then output all entries. If one of $ 12_{6j},13_{6j}$ is missing, use the same procedure ignoring the missing entry. \[prop:GiBases\] Let $G_i'$ be a permutation obtained by removing a single entry from $G_i$. Then $G'_i\in S(3,\infty)$. We give a deterministic procedure to sort $G_i'$. There are three cases depending on from where the entry is removed. *Term removed from $P$.* Let $P'$ be the factor $P$ with one entry removed. We claim that there is a sorting sequence for $P' x_0$ which outputs the smallest six items in order and leaves $10,9$ in stack $R$. To show this we simply consider all cases. 1. If $1$ is removed, $2,4,3$ can be output in order, then $7,6$ placed in stack $L$, $10$ in stack $R$, then $5,6,7$ output, and $9$ placed on top of $10$ in stack $R$. 2. If $2,3$, or $4$ are removed, write $P'=ab761$ with $a,b\in\{2,3,4\}$. Place $a,b$ in stack $R$, move $7,6$ into stack $L$, output $1$, then output $a,b$ in the correct order, then move $10$ into stack $R$, output $5,6,7$ and move $9$ into stack $R$. 3. If $6$ or $7$ is removed, write $P'=243a1$ with $a\in\{7,6\}$. Place $4,3,2$ in stack $L$ in order, move $a$ into stack $R$, output 1 then $2,3,4$, then move $a$ into stack $L$, move $10$ into stack $R$, output $5,a$ and move $9$ into stack $R$. Thus after inputting $P'x_0$ we have the configuration shown in Fig. \[fig:Premoved2\] with $j=0$, which we can sort by Lemma \[lem:can\_sort1\]. *Term removed from $x_s, 0\leq s\leq i$.* Input $P$ leaving $6,7$ in stack $R$, which brings us to the configuration in Fig. \[fig:67\] with $j=0$. Now assume we have input $P\dots x_{j-1}y_{j-1}$ with $j\leq s$ (note the convention that $x_{-1},y_{-1}$ are empty) and the configuration is as in Fig. \[fig:67\]. (0,1.7) – (0,-2.5) – (1,-2.5) – (1,1.7); (2.5,-.5) node [$R$]{}; (1.8,1.7) – (1.8,0) – (3.2,0) – (3.2,1.7); (0.5,-3) node [$L$]{}; (4,2.4) – node\[above\] (2.66,2.4) – (2.66,1.7); (5.8,2.4) node [$x_j\ y_j\dots \text{ or } x_s'y_s\dots $]{}; (2.33,1.7) – (2.33,2.4) – node\[above\] (0.66,2.4) – (0.66,1.7); (-1.2,2.4) – node\[above\] (0.33,2.4) – (0.33,1.7); (2.5,.8) node [$12_{6(j-1)}$]{}; (2.5,0.3) node [$13_{6(j-1)}$]{}; If $j<s$ we can input $x_jy_j$ into the stacks to arrive at the same configuration with $j$ incremented by $1$, as follows: move $10_{6j}$ to stack $L$, output $5_{6j},6_{6j}=12_{6(j-1)},7_{6j}=13_{6(j-1)}$, move $9_{6j}$ to stack $L$, move $13_{6j},12_{6j}$ to stack $R$, output $8_{6j},9_{6j},10_{6j}$. If $j=s$, we proceed as follows: 1. If $5_{6s}$ removed, output $6_{6s}=12_{6(s-1)},7_{6s}=12_{6(s-1)}$, move $9_{6s},10_{6s}$ to stack $R$, to reach the configuration in Fig. \[fig:Premoved2\] with $j=s$. From here the remaining entries can be sorted by Lemma \[lem:can\_sort1\]. 2. If $10_{6s}$ is removed, output $5_{6s}, 6_{6s}, 7_{6s}$ and place $9_{6s}$ in stack $R$, to reach the configuration in Fig. \[fig:Premoved2\] with $j=s$ and $10_{6s}$ missing. From here the remaining entries can be sorted Lemma \[lem:can\_sort1\]. 3. If $9_{6s}$ is removed, move $6_{6s}$ to stack $L$, move $10_{6s}$ on top of $7_{6s}$ in stack $R$, output $5_{6s}, 6_{6s}$, move $13_{6s}, 12_{6s}$ into $L$, then output $8_{6s}, 10_{6s}$. This gives the configuration in Fig. \[fig:67\_2\] with $j=s$. From here the remaining entries can be sorted by Lemma \[lem:can\_sort2\]. *Term removed from $y_s, 0\leq s\leq i$ or $S_i$.* Input $Px_0$ to reach the configuration in Fig. \[fig:Si\_removed\] with $j=0$: move $2,3,4$ into stack $L$, $7,6$ to $R$, output $1,2,3,4$, move $10$ into $L$, output $5,6,7$ then move $9$ into $L$. (0,1.7) – (0,-2.5) – (1,-2.5) – (1,1.7); (2.5,-.5) node [$R$]{}; (2,1.7) – (2,0) – (3,0) – (3,1.7); (0.5,-3) node [$L$]{}; (4,2.4) – node\[above\] (2.66,2.4) – (2.66,1.7); (2.33,1.7) – (2.33,2.4) – node\[above\] (0.66,2.4) – (0.66,1.7); (-1.2,2.4) – node\[above\] (0.33,2.4) – (0.33,1.7); (0.5,-1.8) node [$10_{6j}$]{}; (0.5,-1.3) node [$9_{6j}$]{}; Now suppose we have input $P x_0 y_0\ \dots \ x_{j}$ to reach the configuration in Fig. \[fig:Si\_removed\]. If no entry is removed from $y_j$ and $j<i$ then we can input $y_jx_{j+1}$ to return to the configuration in Fig. \[fig:Si\_removed\] with $j$ incremented by $1$ as follows: move $13_{6j},12_{6j}$ to stack $R$, output $8_{6j},9_{6j},10_{6j}$, move $10_{6(j+1)}$ to $L$, output $5_{6(j+1)}=11_{6j}, 12_{6j}, 13_{6j}$, then move $9_{6(j+1)}$ to stack $L$. If $j=s$ ($y_s$ is removed): 1. If $8_{6s}$ is removed, output $9_{6s},10_{6s}$, move $

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ikipedia page for the maths. Birthday_problem My approach: Generate random numbers in range [0 - 364] add them to a set until a duplicate is generated (set.add returns false) add the count (or set size) to a list repeat this X-times calculate the average of the list Code: public static void main(String[] args) { List<Integer> list = new ArrayList<>(); for(int i = 0; i<10000; i++){ int count = 0; Set<Integer> set = new HashSet<>(); while(set.add(ThreadLocalRandom.current().nextInt(0, 365))){ count++; } list.add(count); } double avg = list.stream().mapToInt(Integer::intValue).average().getAsDouble(); System.out.println(avg); } My output is always under 24. E.g 23.6285 I've tried to run the for-loop 1000, 10000, 1000000 times I've tried ThreadLocalRandom.current().nextInt(0, 365), nextInt(0, 364), nextInt(0, 366) I've tried list.add(count); and list.add(set.size()); But I'am getting always an average < 24. Mostly something like 23.629237. Do you see any mistakes and why I'am not getting the correct value, which is approx. ≈24.61659? A: Note that your answer is almost exactly 1 less than the expected. That's a clue: it tells you that you're probably under-counting by 1, which is a very common bug. Consider your condition: while(set.add(<newPersonsBirthday>)){ count++; } That won't count the last person! They won't be added to the count, and so you're not including them in the set of people in the room. You've counted everybody in the set except the person who triggered the match -- but they're part of the set. Just add count + 1 to your list, to account for that person. Q: Elasticsearch filter results excluding by id I need to return results that do not include docs with certain ids. Elasticsearch allows us to specify which ids are allowed but I see no way to disallow certain ids. In my case I want to not return things the user has already seen so the list will be different for each user. A: You can achieve this by adding a bool/must_not filter containing an ids filter with an array of ids you don't want to appear, like this: { "query": { "bool": { "must": [ ... <--- your other filters go here ], "must_not": [ { "ids": { "values": [ "id1", "id2" <--- add all the ids you DON'T want in here ] } } ] } } } Chikungunya infection is caused due to the chikungunya virus which is transmitted to humans by the bite of infected mosquitoes. The virus is spread by the female species of two different kinds of mosquitoes namely, Aedes aegypti and Aedes albopictus. The origin of Chikungunya dates back to the 1950s in Tanzania. In Makonde, the word loosely translated to “walking bent over”. This is because the virus causes severe joint and muscle pain making the patient walk bent over due to back pain. Chikungunya was once considered to be a disease of the tropics. However, now cases have been documented in well over one-quarter of the countries around the globe. Chikungunya is a major health issue in India affecting billions. After 2010, India saw a decline in the instances until 2016, when a massive outbreak nudged the country severely. Signs and Symptoms It takes around 3 to 7 days after a person is bitten by chikungunya mosquitoes for signs and symptoms to show up. The most common symptoms are fever which can be as high as 104 °F and severe joint pain. Chikungunya may not be a deadly infection but the symptoms can be disabling and severe. Other symptoms include muscle pain, headache, tiredness, rash or joint swelling. Less common symptoms include vomiting, nausea, conjunctivitis, and maculopapular rash. These symptoms are short-lived. Most people start to recover within a week’s time. A majority of infections can cause arthritis and arthralgia months or years after the initial infection. Who are More at Risk? Newborn babies who get infected with the virus are at risk of suffering from a more severe form of this ailment. Elderly people due to weak immunity and those with medical conditions such as heart disease, diabetes or high blood pressure are also more susceptible to chikungunya. The silver lining to this ailment is that once a person has suffered from chikungunya, the risk of getting it again is extremely low as the person becomes immune to it. Diagnosis Chikungunya symptoms are similar to Zika and dengue. These diseases are also transmitted by the bite of the same mosquitoes that spread chikungunya. Thus, sometimes chikungunya is misdiagnosed especially in those areas where all these diseases are common. It is extremely important to rule out dengue fever at the earliest due to its higher mortality rate than chikungunya. Visit a doctor as soon as you suspect having chikungunya symptoms or if you have visited a place recently where chikungunya is prevalent. Since the definitive diagnosis can be done only by running blood tests due to the similar nature of the symptoms with other conditions, the doctor may advise getting some tests done. Complications There are certain complications that may arise when a person suffers from chikungunya. These include: Uveitis Retinitis Meningoencephalitis Myocarditis Hepatitis Guillain-Barré syndrome syndrome Cranial nerve palsies Nephritis Hemorrhage Myelitis Is There Any Vaccine Available? Unfortunately, there is no vaccine to prevent or treat chikungunya. India and the United States of America are continuing with their research to develop it. Treatment There is no specific treatment for this ailment. Generally, people get better by themselves within 7 days and recover completely thereafter. However, joint pain may take much longer to get better. Doctors offer treatment for symptomatic relief with fever and pain medicines. The patient must drink plenty of fluids to prevent dehydration and take plenty of rest to get better sooner. If you or a dear one exhibit symptoms of chikungunya, get checked today. Nightingales offer home-based medical services ranging from doctor consultation to laboratory services. To know more about how we can help or to book a test, consult a Doctor at home, visit us at https://www.nightingales.in/ Reference – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682881/ Image Credits – People photo created by freepik – www.freepik.comjQuery(window).load(function() { pf_switch_status_look(); console.log('Loaded: PressForward Alterations'); jQuery('body.post-type-pf_feed').on('click', '.edit-post-status', function(){ console.log('click edit status'); pf_switch_status_look(); }); jQuery('body.post-type-pf_feed').on('click', '.save-post-status', function(){ console.log('save edit status'); pf_switch_status_look(); }); jQuery('body.post-type-pf_feed').on('click', ".refresh-feed", (function(evt){ evt.preventDefault(); var element = jQuery(this); console.log('Refreshing feed.'); console.log( element ); var feed_id = element.attr('data-pf-feed'); jQuery.post(ajaxurl, { action: 'ajax_update_feed_handler', feed_id: feed_id }, function(response) { //jQuery('.loading-'+itemID).hide(); //jQuery(".result-status-"+itemID+" .msg-box").html(response); //alert(response); //jQuery("#test-div1").append(data); }); }) ); }); function pf_switch_status_look(){ jQuery('body.post-type-pf_feed #submitdiv h3.hndle span').text('Activate'); jQuery('body.post-type-pf_feed').find('#post_status option[value="draft"]').text('Inactive'); jQuery('body.post-

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_0).$$ While from Eq. (\[eq:delta\_theta\]), the angular fluctuations are given by $$\delta\Theta^2 = 4\, (\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]})(\ell_{[\gamma}A_{\delta ][ \rho}\ell_{\sigma]})s^{\alpha}k^{\beta}t^{\mu}k^{\nu}s^{\gamma}k^{\delta} t^{\rho}k^{\sigma}F(\omega_g,s,t_0).$$ Interestingly, since $F(\omega_g,s,t_0)$ is independent of the displacement parameter, $\alpha$, so are $\delta\xi^2$ and $\delta\Theta^2$. Therefore, the fluctuations depend only on the squeezing parameter, $\zeta$, and we can immediately say that a coherent state (classical wave) for which $\zeta=0$ induces no fluctuations. For the following calculations, we assume the passing gravity waves are in the Transverse Tracefree (TT) Gauge. However, note that since our results derive from the Riemann tensor, the equations are gauge invariant, and we use the TT gauge only for calculational convenience. To begin, note that if the gravity waves and photons travel in parallel, then one finds $(\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]}) t^{\alpha}k^{\beta}t^{\mu}k^{\nu} = 0$. This indicates that there is no induced redshift fluctuation nor angular blurring due to a squeezed state gravity wave traveling with the photons. This is as one might expect, since a gravity wave in the TT gauge has only non-zero transverse components. We may subsequently restrict our attention to transversely propagating gravity waves and will assume the gravity waves to propagate with $\ell^{\mu}=\omega_g(1,0,0,1)$ while the photons continue to have wave vector $k^{\mu}=(1,1,0,0)$. We define $$\mathfrak{F}(\omega_g,s,t_0)= [1-\cos(\omega_g s)][1-\cos(\omega_g t_0)] [\cosh(2r)-\sinh(2r)\cos(\theta-\omega_g(t_{0}+s))-1]\, ,$$ so that for a gravitational wave propagating in the z direction, for which $\ell_x=0$, $$F(\omega_g,s,t_0) = \frac{16}{{\omega_g}^4}\mathfrak{F}(\omega_g,s,t_0) \,.$$ ### Redshift Fluctuations {#rfcase} With transversely propagating gravity waves, $$(\ell_{[\alpha} A_{\beta ][ \mu} \ell_{\nu]})t^{\alpha}k^{\beta}t^{\mu}k^{\nu} = -\frac{1}{4}\omega_g^2 A_{+}\, ,$$ and therefore $$\label{rfcase2eq} \delta\xi^2 = 4\, A_{+}^2 \mathfrak{F}(\omega_g,s,t_0).$$ There exists a non-zero effect which in this case depends only on the $(+)$ polarization. For a gravity wave propagating in the $z$-direction, $A_+ = A_{xx} =-A_{yy}$. ### Angular Blurring {#abcase} #### Case 1 Let the photons propagate in the x direction while the gravity waves propagate in the z direction and probe the y component of angular blurring, $s^{\mu}=(0,0,1,0)$. We find $$(\ell_{[\alpha} A_{\beta ][ \mu}\ell_{\nu]})s^{\alpha}k^{\beta}t^{\mu}k^{\nu} = \frac{1}{4}\omega_g^2 A_{\times}$$ and $$\label{abcase2eq} \delta\Theta_y^2 = 4\, A_{\times}^2\mathfrak{F}(\omega_g,s,t_0).$$ Note that here the y component of blurring depends only on the $(\times)$ polarization of the gravity waves. Here $A_{\times} = A_{xy}=A_{yx}$. #### Case 2 To probe the z component of blurring, set $s^{\mu}=(0,0,0,1)$. The result is $$\label{abcase3eq} \delta\Theta_z^2 = 4\, A_{+}^2\mathfrak{F}(\omega_g,s,t_0)\, ,$$ which is the same as Eq. (\[rfcase2eq\]) for redshift fluctuations, and only depends on the $(+)$ polarization of the gravity waves. Classical Time Dependent Variation ---------------------------------- As noted above, the fluctuations in redshift and angle depend upon the degree of squeezing, measured by the parameter $\zeta$. In this subsection, we will examine the expectation value of the change in fractional redshift, $\langle\Delta\xi\rangle$ and in angle, $\langle\Delta\Theta\rangle$. These quantities will depend only upon the displacement parameter $\alpha$, and hence would be the same in the coherent state $|\alpha,0 \rangle$ as they are in the squeezed state $|\alpha,\zeta \rangle$. For this reason, we regard these quantities as giving the classical time-dependence. Alternative approaches to the classical time-dependence of these quantities may be found in Refs. [@Weber; @Zipoy; @Kaufmann] Here it is possible to calculate $\langle\Delta\xi\rangle$ as a single integration of the Riemann tensor over the spacetime region $da$ via Eq. (\[RateOfChange\]). However, for comparison purposes, we calculate $\langle\Delta\xi\rangle^2$ directly. In this case, $$\langle\Delta\xi\rangle^2 = \int da \int da' \,\langle\hat{R}_{\alpha\beta\mu\nu}(x)\rangle \langle\hat{R}_{\gamma\delta\rho\sigma}(x')\rangle t^{\alpha}k^{\beta}t^{\mu}k^{\nu}t^{\gamma}k^{\delta}t^{\rho}k^{\sigma}\, ,$$ where now $$\langle\hat{R}_{\alpha\beta\mu\nu}(x)\rangle \langle\hat{R}_{\gamma\delta\rho\sigma}(x')\rangle = 4 \sum_{l} (\ell_{[\alpha} A_{\beta][\mu}\ell_{\nu]})(\ell_{[\gamma} A_{\delta][\rho}\ell_{\sigma]}) f'(x,x')$$ with $$f'(x,x') = \alpha^2 e^{i\ell_{\tau} (x^{\tau}+x^{\prime\tau})} + (\alpha^{\ast})^2 e^{-i\ell_{\tau} (x^{\tau}+x^{\prime\tau})} + 2\vert\alpha\vert^2\cos[\ell_{\tau} (x^{\tau}-x^{\prime\tau})].$$ Integration of $f'(x,x')$ over the spacetime region of Fig. \[spacetime\] yields $$\begin{aligned} & & F'(\omega_g,s,t_0) = \int da \int da' \, f'(x,x') = \nonumber \\ & & \frac{16\{1-\cos[s(\ell_x-\omega_g )]\} [1-\cos(\omega_g t_0)]} {\omega_g^2(\ell_x-\omega_g)^2} \left(\alpha e^{\frac{i}{2}[\ell_x s-\omega_g(s+t_0)]} + \alpha^{\ast} e^{-\frac{i}{2}[\ell_x s-\omega_g(s+t_0)]}\right)^2.\end{aligned}$$ Thus the classical time variation of the redshift is characterized by: $$\label{classical} \langle\Delta\xi\rangle^2 = 4\, F'(\omega_g,s,t_0) (\ell_{[\alpha} A_{\beta][\mu}\ell_{\nu]})(\ell_{[\gamma} A_{\delta][\rho}\ell_{\sigma]}) t^{\alpha}k^{\beta}t^{\mu}k^{\nu}t^{\gamma}k^{\delta}t^{\rho}k^{\sigma}.$$ For the case of redshift variations with photons and a gravity wave propagating perpendicularly (Sect. \[rfcase\]), $$\label{rfclassical} \langle\Delta\xi\rangle^2 = 4 \,A_{+}^2 \mathfrak{F'}(\omega_g,s,t_0).$$ Here $\mathfrak{F'}(\omega_g,s,t_0)$ is defined in a similar way as $\mathfrak{F}(\omega_g,s,t_0)$ when $\ell_x=0$, $$\mathfrak{F'}(\omega_g,s,t_0) = [1-\cos(\omega_g s)][1-\cos(\omega_g t_0)] \left(\alpha e^{-\frac{i\omega_g}{2}(s+t_0)} + \alpha^{\ast} e^{\frac{i\omega_g}{2}(s+t_0))}\right)^2.$$ The classical time variation of angular position yields similar results. Particularly, for perpendicularly propagating photons and

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all-around gain the nation could reap from the adoption and application of biotechnology cannot not be overemphasized, she said. Categories<!DOCTYPE html>  <title>OffscreenCanvas test: 2d.state.saverestore.transformation</title> <script src="/resources/testharness.js"></script> <script src="/resources/testharnessreport.js"></script> <script src="/html/canvas/resources/canvas-tests.js"></script> <h1>2d.state.saverestore.transformation</h1> <p class="desc">save()/restore() affects the current transformation matrix</p> <script> var t = async_test("save()/restore() affects the current transformation matrix"); var t_pass = t.done.bind(t); var t_fail = t.step_func(function(reason) { throw reason; }); t.step(function() { var offscreenCanvas = new OffscreenCanvas(100, 50); var ctx = offscreenCanvas.getContext('2d'); ctx.fillStyle = '#0f0'; ctx.fillRect(0, 0, 100, 50); ctx.save(); ctx.translate(200, 0); ctx.restore(); ctx.fillStyle = '#f00'; ctx.fillRect(-200, 0, 100, 50); _assertPixel(offscreenCanvas, 50,25, 0,255,0,255, "50,25", "0,255,0,255"); t.done(); }); </script> If you grew up watching football, you likely know where most of the color-commentary broadcasters came from. Think of John Madden. Just about everyone knows that he started as a player in the National Football League. He later went on to coach the Oakland Raiders to a Super Bowl before his long career commentating on games. What I didn’t know is that story just about sums up Marcus Graham’s career. Better known under his “djWheat” pseudonym, Graham is an e-sports commentator, online talk-show host, and business professional in e-sports and online broadcasting. I knew of him from watching a few StarCraft II matches and from his Live On Three e-sports show that I’ve watched a few times. As a relative outsider to e-sports, I always thought that Graham woke up one day, saw how big e-sports is getting, and decided to take a crack at broadcasting it. The truth is that he was doing this job before we even had a name for it. “I’m an older guy,” said Graham. “A lot of people don’t necessarily know the history. They’re like, ‘Why is this guy even qualified to talk about video games on any level?’ Before there was broadcasting — before people were even considering broadcasting these types of events we do now — I was a player.” Graham got his start in competitive gaming — this was before anyone had coined the term “e-sports” — as a player on one of the top-ranked North American Quake II team-deathmatch teams. He was the leader of Clan 519, and he would travel with his team and compete in LAN parties for money. Image Credit: Graham “I have a huge competitive fire inside me,” he said. “The interest in playing was always there.” As Graham got into his 20s, he began to put that fire aside in favor of something that he could support himself with. “One day, as I was about 21-years old, I said to myself, ‘You know what? I love to play video games. I really love to play Quake and travel around the U.S. and compete,” said Graham. “But the fact of the matter is, I’ve gotta get a job. And I’ve gotta get a job fast. At the time I was very PC-centric. I happened to get a job with a tech company right around the Y2K boom, when they were hiring anyone who knew anything about computers. This was great for me, because it allowed me to have a full-time job, and then when I wasn’t working, I was playing and doing what I could for the team.” For Graham, doing what he could meant taking on the role of de facto coach. He decided one of the best ways he could do this was to watch the games and comment over them. That way he could call out smart moves and help the other players work on recognizing and addressing their errors. “I probably did three or four of these before one of my guys came to me and said, ‘I don’t know if the other guys are actually listening to what you’re doing, but you should try to do this like it’s a sports game. Try to commentate. Your passion is obviously strong enough there. You’re almost doing it already.'” The idea immediately took root in Graham’s imagination, and he began researching how he would go about doing something like that. “I looked for different technology,” he said. “This was about 1999 into 2000, and so the first technology I ever used to stream was actually a RealAudio server. I could have 25 people, max capacity, listening. I filled it up every night, and I thought I was just the bee’s knees because there were 25 people interested in hearing about these Quake games that were happening.” RealAudio is a streaming audio codec that individuals can use to stream music and audio content over the web. RealNetworks designed it specifically for low-bandwidth connections like dial-up modems. As fun as it was, the 25-person limit forced Graham to move on to other technology. That’s when he found WinAmp’s Shoutcast software. Shoutcast was similar to RealAudio, but it provided the opportunity for Graham and others to host Internet “radio stations” that could handle up to 1,000 simultaneous listeners. “That’s what ended up happening,” he said. “I started doing, independently, my own radio broadcasts for Quake. I eventually ended up joining a group of guys that were called TSN, the Team Sportscast Network. They did the same thing, where they had their own servers. I was their Quake broadcaster.” The Team Sportscast Network covered a wide variety of games although it specialized on the Tribes franchise. The format was so popular in certain gaming circles that a lot of people still refer to game commentators as “shoutcasters.” “I ended up leaving that place and starting my own little station called Inside the Game,” said Graham. “But TSN was kind of the start of it all.” The first commentator In 1999, a handful of people were starting to use platforms like Shoutcast to talk about competitive games. That’s also when people started commentating live matches, but Graham says it is difficult to know who was first. “I think there were a lot of examples of people doing [commentary] where they didn’t even realize they were doing it,” he said. “For that reason, it is really hard to pinpoint who was the first person that was actually out there broadcasting these things. I’ve been labeled that guy several times, but I don’t even know that I can take that credit.” It wasn’t until 2002, says Graham, when companies like MLG were founded, that a wider audience began to realize that game commentators were a real thing. “I think that was the first year that this hobbyist activity really became a reality.” Before it was cool … or profitable The early days of game broadcasting and commentating were very different. Today, organizations like MLG have full-time play-by-play, analyst, and color-commentary people. Those companies keep many of them on salary, fly them out to events, and even get them tailored suits. Those are the kinds of things that Graham rarely received and most of the time had to pay for himself at the beginning. “On the one hand, I was the talent,” he said. “I was the guy who got on the microphone and did his thing. But at the same time, because I was so into computers and so into the technical aspects of broadcasting, I often played the roles of talent, producer, and director all at the same time. The challenges were ridiculously hard.” Graham was essentially running his own production company as a hobby. He and his team would have to drag thousands of dollars worth of equipment to events around the country and ask organizers to provide tables, Internet access, and access to the game. This was all before video streaming. Hell — this was before YouTube. Graham would set up a situation similar to what an AM radio network has at a sports arena. He would set up a beefy audio-streaming station and watch the game and broadcast over it. Ideally, gamers would also watch the game, typically Quake, through a spectator mode in the title itself as well. “But the logistics were kind of like, us knocking on companies’ doors and saying: ‘Hey! This is a cool thing that we do. Let us come to your place and do it.’ We paid our way for years to events. That was just because, partially,

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com is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through TheBodyPRO.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.1. Field of the Invention The present invention relates to a suspension arrangement for a hydraulic elevator. 2. Description of the Background Art At present, conventional hydraulic elevators are implemented as rucksack-type elevators in which the elevator car is mounted on a supporting frame resembling a rucksack. As to their suspension, these elevators are either of a direct-acting or an indirect-acting type. Direct-acting elevators of normal construction without an expensive telescopic cylinder are only applicable in low-rise buildings where the elevator only serves one or two floors. Therefore, most hydraulic elevators employ an indirect-acting type of suspension. Such elevators usually have a hoisting height of 3.5-15 m, corresponding to 2-6 floors. The maximum hoisting height is about 20 m. In an indirect-acting elevator, a hoisting rope attached to a fixed column is passed over a diverting pulley mounted on top of the piston and further to the car frame supporting the elevator car. Due to this roping, the car travel equals twice the stroke of the piston, which is why this type of suspension is termed 2:1 suspension. However, this widely used suspension system has certain serious drawbacks. First, since the length of the cylinder (and the piston inside it) equals at least half the entire hoisting height, difficulties are encountered in transporting such a long cylinder into the elevator shaft. The cylinder is usually brought into the shaft via its door opening, in which case the cylinder may be at most about as long as the guide rail bar, i.e. about 5 m. This limits the hoisting height to 10 m, corresponding to four floors. When larger hoisting heights are to be achieved, the cylinder has to be hoisted into the shaft via the top of the shaft. However, this is only possible at an early stage of the construction work, and it is necessary to schedule the transport and hoisting of the cylinder into the shaft accordingly. This causes extra work and expenses. Moreover, the cylinder has to be protected in the shaft during construction, and it is always more or less of a hindrance to other work. Another solution applied in the case of large hoisting heights is to use an extendable cylinder. In this case, the cylinder is composed of two sections which are only joined together in the shaft. However, because of the threaded joint, the cylinder has to be manufactured from a thicker tube than a jointless one. Because of the joint, the manufacture of the cylinder and especially its final grinding is an elevator- and cylinder-specific and expensive job. The testing of the cylinder also requires special arrangements, and joining the cylinder sections and installing the cylinder in a narrow and dirty space is difficult and expensive. A jointed cylinder costs at least one and a half times as much as a jointless one. Another limitation in the case of 2:1 suspension, in addition to the problem of moving the cylinder into the shaft, is the risk of buckling of the piston tube at larger hoisting heights. This limits the hoisting height and makes it necessary to increase the thickness of the wall of the piston tube. However, this increases the weight of the piston, thus reducing the usable hoisting capacity of the cylinder. Moreover, due to the material costs, this is an expensive solution. Another way to solve the buckling problem is to use reinforcements to prevent buckling, but this also involves additional costs.Small intestinal development in growth-retarded fetal sheep. The functional maturity of the gastrointestinal system is essential for the survival of the neonate. The effects of reducing placental size and the ensuing fetal growth retardation on the development of the small intestine (SI) of the sheep fetus were investigated. At 140 days of gestation (term is 147 days), fetal body weight, gastrointestinal weight (from the abomasum to the rectum, i.e., the gut), SI weight, and SI length in the growth-retarded fetuses (n = 6) were significantly reduced (p less than 0.05) when compared with age- and breed-matched control fetuses. The SI weight was disproportionately reduced as a fraction of the gut weight or SI length (p less than 0.01). The proximal SI showed marked reductions in the thickness of the wall, muscularis externa, mucosa, villus height, and crypt depth (p less than 0.003). Densities of villi and crypts were also reduced (p less than 0.02). The crypt-to-villus ratio was maintained. Glycogen was accumulated basally in the villus epithelial cells, and their nuclei were located apically. These characteristics are comparable to those of much younger fetuses. In the distal SI, interanimal variation was large; however, the mean thickness of the wall, the muscularis externa, the mucosa, and the villus height were all reduced (p less than 0.05). In this region, the density of villi and crypts, the pattern of glycogen accumulation, and the position of the nuclei did not markedly differ between growth-retarded and control fetuses. Villus cell density was increased (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS) #----------------------------------------------------------------------------- # _MatchMac # # Takes any number of MAC addresses and attempts to find a matching comment # in the "ethernetMACs.txt" file. #----------------------------------------------------------------------------- sub _MatchMac(IN string $macs, OUT string %macTypes) { string $macFile = "ethernetMACs.txt"; @echo off; @record on; ifnot (`getdirectory -scripts`) { echo "* MatchMac: Unable to get scripts directory"; return false; } @record off; string $dir = GetCmdData("dir"); ifnot (defined($dir[0])) { echo "* MatchMac: Unable to retrieve scripts directory"; return false; } string $lines; ifnot (ReadFile("$dir\\..\\$macFile", $lines)) { echo "* MatchMac: Error reading MAC listing file"; return false; } int $numLines = sizeof($lines); if ($numLines == 0) { echo "* MatchMac: No matching lines in MAC listing file"; return false; } string $line; foreach $line ($lines) { string $addrs = Split(":", $line); if (sizeof($addrs) > 2) { # good line string $mac; foreach $mac ($macs) { string $macParts = Split(" ", $mac); if ((sizeof($macParts) == 6) && ($macParts[0] == $addrs[0]) && ($macParts[1] == $addrs[1])) { string $last = Split(" ", $addrs[2]); if ((sizeof($last) > 1) && ($last[0] == $macParts[2])) { # we have a match %macTypes{'$mac'} = $last[1]; } } } } } return true; } /* end _MatchMac */Availability: Normally ships in 10 days Part Number:CI-FT-218 Quantity Description The St. Aubin Wall Garden Fountain is the perfect choice for your home, garden, patio, or other social gathering area. Water flows out the decorative center of the flower detail on the top of the back piece of the Wall Fountain. The St. Aubin Wall Fountain will make the perfect center piece. Color shown is Alpine Stone. The patinas are designed to replicate the look of natural aging, but unlike a painted finish, the patinas do not prevent the natural aging process. Any cast stone item with a patina finish will weather naturally in an outdoor environment. Because each patina is hand applied in a multi-step process and the product is photographed in natural settings, actual colors may vary. The acid stains create a bold, new look. These rich multi-dimensional colors bring a new depth and dimension to the cast stone product. The mixture of water, metallic salts, and muriatic acid create permanent stains in the surface of the concrete which will not flake or peel. Like stains for wood, each piece will accept the stain in varying degrees of intensity, creating natural color variations that brings character and distinction to each peace. NOTE: This product includes special ordering instructions. Please read the 'Special Ordering Instructions' section above before placing an order.#!/usr/bin/python # coding=utf-8 # # Copyright 2003 Sandia Corporation. # Under the terms of Contract DE-AC04-94AL85000, there is a non-exclusive # license for use of this work by or on behalf of the # U.S. Government. Redistribution and use in source and binary forms, with # or without modification, are permitted provided that this Notice and any # statement of authorship are reproduced on all copies. # from __future__ import

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: Adobe Homes in the Desert" Host David Yetman and expert architect Bob Vint travel around Tucson, Arizona, to see how adobe - the perfect desert building material - was used in the past and is still used today. Adobe not only has a remarkable period of longevity, but also has thermal capabilities, making it ideal for the hot dry desert. Yetman and Vint spend time at the San Xavier Mission to watch a restoration crew use new adobe to repair and restore the existing adobe exterior. D 7:30 am Kevin Dundon's Modern Irish Food"Transformations" Kevin serves up a crock of Kilmore Quay mussels with bacon in white wine. Next it's chicken thighs with Asian stuffing and a sticky teriyaki glaze followed by Hasselback potatoes; cherry tomato and roasted garlic soup; and a Kinky Eton mess served with basil oil. D 8:00 am Taste of History"Bartram's Gardens: A Revolution In Gardening" The Philadelphia gardens of botanists John and William Bartram were a favorite excursion for our founding fathers, including Ben Franklin. In this episode, learn how Franklin introduced tofu to America and watch Chef Walter cook Fried Lafayette Fish, Curried Tofu with Shrimp, Turbot and Braised Romaine, in the hearth of Bartram's kitchen. D 8:30 am Simply Ming"Wakiya - Ramen" Nothing says Japan like Ramen noodles - this episode of Simply Ming brings Chef Ming Tsai on the road to the Instant Ramen Museum in Osaka, Japan. Ming also learns the secrets of cooking Ramen from famous Japanese Chef Yuji Wakiya. D 9:00 am The Jazzy Vegetarian"Good Morning Fiesta" Host Laura Theodore prepares a zesty breakfast menu featuring "Tofu Ranchero," a slightly spicy dish served with fresh tomato sauce. For a baked treat, "Cornbread and Sweet Pepper Mini-Muffins" wakes up sleepy taste buds, while "Pineapple, Banana and Strawberry Smoothie" presents a frosty and fruity beverage to get the morning started on an energizing note. D 9:30 am Chef's Life"The World Is Your Oyster" Vivian goes to Cedar Island to explore the new culture of farm-raised oysters in the Southeast. She and Ben share plans of opening an oyster bar across the street from Chef & the Farmer in hopes it will be a place that adds character and variety to the tiny town's "dining scene." Vivian and her dad orchestrate their family's first-ever oyster roast and are blown away by how much everyone enjoys it. D 10:00 am Austin City Limits"Sarah Jarosz/The Milk Carton Kids" Showcasing new acoustic music, multi-instrumentalist Jarosz highlights her album Build Me Up From Bones. Then the Milk Carton Kids play folk songs from their album The Ash & Clay.G Dinosaur Train"That's Not A Dinosaur/Tiny's Garden" The kids visit the Big Pond to attend the Biome Block Party. While attempting to win the leaf-necklace contest, Keenan Chirostemotes claims the Pteranodon sibs can't compete for the prize for "dinosaur" with the most leaves because they are not dinosaurs. This launches the kids into a song called "That's Not a Dinosaur", as all the non-dinosaurs sing their piece. D 12:30 pm Peg + Cat"The Slop Problem/The Birthday Present Problem" The Slop Problem - The Farm. Peg and Cat enlist the Teens to help them figure out how to clean filthy farm animals of various sizes. Primary Content: More, less; Secondary Content: Counting by fives up to 25. D 1:00 pm Cat in the Hat Knows A Lot About That!"Flutter By Butterfly/Pretty In Pink" Flutter By Butterfly - Sally and Nick are pretending to be butterflies, but they're not very good at it. The Cat takes them to meet Bernadette the Monarch butterfly, who can teach them all about fluttering. Following Bernadette from Milky Weed Meadow to Prickly Pines forest they learn that butterfly wings are used for so much more than just fluttering! Pretty in Pink - Sally and Nick are having fun trying out different moves when the Cat arrives to show them some cool moves of his own. D 1:30 pm WordGirl"Two Brains Forgets/Banned on the Run" Two Brains Forgets - It looks like all is lost when Dr 2-Brains discovers WordGirl's secret identity! But some quick thinking, some help from the Botsford family, and a little luck save the day when 2-Brains' amnesia ray ends up working on the Doc himself. Banned on the Run - Mr. Big finally cheats his way to becoming the town Mayor - and his first order of business is to ban Word Girl! WG and Huggy must restore order to the town and undo all of the silly laws Mr Big keeps passing. D 2:00 pm The Mind of a Chef"Gluttony" It's gluttonous goodness in this episode - over-the-top indulgence with Joe Beef chefs Federic Morin and David McMillian's foie gras sandwich, a whiskey tasting mayhem with Chef Sean Brock at Buffalo Trace in Kentucky and the classic dish "Hot Brown" served up three ways. D 2:30 pm Rick Steves' Europe"North Wales: Feisty and Poetic" Rick takes in Mount Snowdon, medieval castles and Victorian promenades. He learns a bit of Welsh, follows a miner deep into a slate mine, and herds sheep with a clever dog.G The Red Green Show"Homemade Cheese" Junior's house develops a major mouse infestation. On Handyman Corner, Red offers pest control tips while Bill demonstrates his skill at cheesemaking.G 7:30 pm Hebburn"Dressing Up Fancy" Hebburn lays down the red carpet for Sarah's parents, Ben and Susan from York, who are visiting the Pearson home for the first time. They get costuming help from Vicky and Denise to attend the fancy dress competition at Swayze's pub in town. But when the competition turns to violence, an unlikely hero is born.G 8:00 pm May to December"The Way You Look Tonight" Zoe feels inadequate when Simone boasts of how domesticated her mother was. Hillary is still infatuated with Anthony, while Vera ponders how to put her off the scent.G 8:30 pm My Family"Harpers & Queen (New Year's Special)" Ben is dressed for an expected New Year's trip to Mauritius, courtesy of Susan. But Susan gets a notice that she is on the New Year's list for MBE honors, Most Excellent Order of the British Empire, placing her among the junior levels of British orders of chivalry. Not wanting to miss the investiture of even a junior level, Susan commands that Ben attend the ceremony, leading to a sticky result.G 9:00 pm My Hero"Zero Tolerance" George collars a robber at the health clinic without superpowers and is invited by Janet's father to join Neighborhood Watch.G 9:30 pm Last of the Summer Wine"Bushes at Dawn" Foggy and Clegg band together to help their friend Compo who discovers Nora with another man.G 10:00 pm As Time Goes By"Branching Out" Jean is opening another secretarial agency and looking for someone to run it. Meanwhile, work for Lionel seems to have dried up.G The Red Green Show"Homemade Cheese" Junior's house develops a major mouse infestation. On Handyman Corner, Red offers pest control tips while Bill demonstrates his skill at cheesemaking.G 11:30 pm Hebburn"Dressing Up Fancy" Hebburn lays down the red carpet for Sarah's parents, Ben and Susan from York, who are visiting the Pearson home for the first time. They get costuming help from Vicky and Denise to attend the fancy dress competition at Swayze's pub in town. But when the competition turns to violence, an unlikely hero is born.GMast cell-nerve interaction in the colon of Trypanosoma cruzi-infected individuals with chagasic megacolon. Chagas disease is an infection caused by the parasite Trypanosoma cruzi that affects millions of people worldwide and is endemic in Latin America. Megacolon is the most frequent complication of the digestive chronic form and happens due to lesions of the enteric nervous system. The neuronal lesions seem to initiate in the acute phase and persist during the chronic phase, albeit the mechanisms involved in this process are still debated. Among the cells of the immune system possibly involved in this pathological process is the mast cell (MC) due to its well-known role in the bi-directional communication between the immune and nervous systems. Using ultrastructural analysis, we found an increased number of degranulated MCs in close proximity to nerve fibers in infected patients when compared with uninfected controls. We also immunostained MCs for the two

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She does recall asking in her freshman year why the football team was allowed to arrive on campus before classes, “but then the field hockey team was allowed to arrive early by my sophomore year.” And while fundraising was a background theme at the June event, attendees did buzz about the ongoing Garcelon Field project to install a FieldTurf surface plus new grandstands, lights, and press box. The $2.6 million project, as a matter of fact, is entirely donor-funded. Bestest Behavior Newly created this year, Bates Best awards recognize significant work by alumni and parents that engages Bates people with the College and that displays passion and commitment for advancing the Bates mission. The Bates Best awards presented at the Volunteer Recognition Dinner in May honored volunteer work during 2009–10, while at the Athletics Celebration, Bates Best awards recognized lasting contributions to the Bates athletics program.package commands type CreatePrivateDomainsCommand struct { BaseCFConfigCommand BasePeekCommand } //Execute - creates private domains func (c *CreatePrivateDomainsCommand) Execute([]string) error { var cfMgmt *CFMgmt var err error if cfMgmt, err = InitializePeekManagers(c.BaseCFConfigCommand, c.Peek); err == nil { err = cfMgmt.PrivateDomainManager.CreatePrivateDomains() } return err } China, euro zone sovereign debt and the potential fallout from Brexit top the escalating list of concerns for the Bank of England (BOE), according to a report published on Wednesday which warns that risks to global stability have spiked in the past six months. The U.K.'s central bank's semi-annual Financial Stability Report states, "Vulnerabilities stemming from the global environment and financial markets, which were already elevated, have increased further since July." Red flag over China Chris Ratcliffe | Bloomberg | Getty Images China's burgeoning debt levels and rapid rate of credit expansion are singled out as significant red flags, with the report noting a 100 percentage point spike in the country's non-financial sector debt relative to gross domestic product (GDP) since the 2008 financial crisis. The ratio currently stands at around 260 percent of GDP. "This is extraordinary leverage for an advanced, let alone, an emerging economy," the BOE Governor Mark Carney said at a press conference to launch the report. The "near-record" pace of net capital outflows from China during the third quarter and a 3 percent depreciation in the Chinese renminbi against the U.S. dollar since the publication of the BOE's July report were also highlighted as reasons for concern. Euro area dynamics Turning to nearer neighbors, the governor broke down the key risks emanating from some euro area economies into, firstly, existing sovereign debt dynamics and, secondly, threats to the resilience of parts of the trading bloc's banking system. Carney noted the vulnerability of elevated sovereign debt levels to a leap in borrowing costs or diminished growth prospects on the back of either trade or political headwinds. Moving even closer to home, the governor raised the looming specter of the U.K.'s impending departure from the European Union (EU), noting banks located domestically currently supply over half of the debt and equity issuance from continental firms and account for over 75 percent of foreign exchange and derivatives activity in the U.K. Consequent fears of contagion were emphasized by Carney as he discussed the risk of a disruption in services provided to the European real economy spilling over to hit the U.K. economy through trade and financial links. While clearly stating that the largest risks to U.K.financial stability are global in nature, the governor went on to acknowledge that a lack of clarity over how Brexit will unfold means many unknowns cloud the current outlook. "It will take time to clarify the U.K.'s new relationships with the EU and the rest of the world. And the orderliness of the U.K. economy's adjustment to these changes will influence the risks to financial stability," Carney said.Q: Enviar funcion con parametros JavaScript Tengo la siguiente linea de codigo: <td border="1" onClick="myFunction()"> Estoy tratando de hacer lo siguiente para poder recibir un valor en la funcion myFunction(variable). <td border="1" onClick="myFunction(variable)"> Pero me envia el siguiente error: is not defined at HTMLTableCellElement.onclick A: Lo que quieres hacer va de la siguiente forma: function myFunction(mensaje) { console.log(mensaje); } table, th, td { border: 1px solid black; } <table> <tr> <td onClick="myFunction('Celda A')">Celda A</td> <td onClick="myFunction('Celda B')">Celda B</td> </tr> </table> Nota: Si quieres enviar algún tipo de variable y te da error, deberás poner mas código en tu pregunta. Melvin Guillard - A Fighting Education When it was announced that Melvin Guillard was going to fight Donald Cerrone at UFC 150 this Saturday, just a little over a month after going three rounds against Fabricio Camoes, many wondered how “The Young Assassin” would react to such a short turnaround time. Short? Guillard considers two fights in a month a vacation compared to his early days in the sport. “I’m a fighter and I love to fight,” he said. “Growing up, when I first started fighting, fighting two, three times, and sometimes six times in one month was normal for me. So fighting this close back-to-back kind of brings back memories of my younger days.” He’s not kidding when he says younger days. Still more than seven months away from his 30th birthday, the New Orleans native has been fighting in one way, shape, or form since he was 14, first as an amateur before turning pro at 16. “I’ve been at it for a long time,” he laughs as he delivers the understatement of the summer. “And even when I turned 16 and turned pro, it was about grinding, and just fighting to make a paycheck. Back then I was making five and five, which was 500 and 500, a thousand and a thousand, and I was living off that money. That was part of the reason why I chose to fight so much at that time.” But in an odd way, fighting Guillard wasn’t just something he was good at; it was a way for him to bond with his father, who passed away in 2006, in a different way than most teens and their dads. “My dad went to every fight, he signed my pro license, and me and my dad were like best friends, so we got to hang out all the time,” said Guillard. “He would go to the bars, watch me fight, take me home, and I even had one of my wrestling buddies, Terry Verdun, he would fight on Friday nights with me. We would go and fight together and just beat people up. That was my hangout, and that was the thing that I was doing because I was hanging out with my high school friend and my dad. Then it blew up so big at home for me to where everybody from home would come and watch me fight. So then I would make money from selling tickets in the neighborhood, and I would have my whole neighborhood coming out once or twice a month to watch me fight and be the main event at the club called Main Event.” Guillard would pile up win after win, and knockout after knockout, some sanctioned by the local commission, some not. It was a heady time for the aspiring UFC fighter, even if he didn’t know at the time whether the UFC was going to be the worldwide juggernaut it is today. The adults around him at school were even less optimistic. “Fighting in the UFC was always my childhood dream and I knew back then that they didn’t make a whole lot of money doing it, but somewhere in there, I thought to myself that this sport might just blow up and take off and it could be big, and I was right,” he said. “I even had schoolteachers and principals, people that were elders to me and mentors that I looked up to, telling me that I was crazy for trying to be an MMA fighter. They thought it was violent and brutal, that guys always got hurt and didn’t make any money, and now those same people are looking at me like ‘kid, you must have known something we didn’t know at the time.’ So it’s definitely refreshing and cool to know that I chose something that other people actually doubted, and I was right about it.” Nearly 14 years after the first time he put the gloves on and got paid for it, Guillard is co-headlining a major UFC event in Denver, and with wins in six of his last eight fights, a big win over Cerrone can put him in the conversation for a world title shot at 155 pounds. And that’s precisely why he took the fight.

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was dripped directly onto the heart as needed for arrhythmia control during ischemia, and procainamide (12.5 mg/kg IP) was administered 15 min prior to reperfusion. Rats were orally gavaged with vehicle (0.5% HPMC, 5% DMSO, and 0.1% Tween 80; 10 mL/kg; *n* = 14), GSK2181236A (0.1 or 1.0 mg/kg; *n* = 11--14), or BAY 60-4552 (0.3 or 3.0 mg/kg; *n* = 10--12) 2 h prior to ischemia. Blood was collected at the initiation of ischemia and after 24 h reperfusion. Plasma was obtained for analysis of compound concentrations and levels of cardiac Troponin I (cTnI), a circulating biomarker of cardiac injury. Plasma concentrations of cTnI were determined using a commercially available ELISA (catalog \#2010-2-HSP, Life Diagnostics, West Chester, PA, USA) according to the manufacturer's instructions. Plasma compound concentrations were determined by LC/MS/MS (API 5000 triple quadrupole mass spectrometer, ABSciex, Foster City, CA, USA; Prominence liquid chromatographic system, Shimadzu, Columbia, MD, USA). Rats were anesthetized with a mixture of ketamine and xylazine (35 and 5 mg/kg, IM) and euthanized via exsanguination. Hearts were excised and perfused with 1% Evans blue dye in saline then perfused-fixed with 10% neutral buffered formalin (∼90 mmHg perfusion pressure). Hearts were sliced on the short axis from apex to base at 1--2 mm intervals, and the ischemic area (area at risk) was evaluated using Image Pro-Plus (Media Cybernetics, Inc., Bethesda, MD, USA). Fresh heart slices were stained with 1% triphenyltetrazolium and evaluated using Image Pro-Plus for determination of infarct size. Cardiac and renal function assessment of GSK2181236A and BAY 60-4552 in HSFD fed SHR-SP --------------------------------------------------------------------------------------- The SHR-SP is an established model of genetic hypertension. Exposure to a HSFD exacerbates endothelial dysfunction, systemic vascular resistance and hypertension, and accelerates end-organ damage (Ma et al., [@B21]). Decreases in endothelium-dependent vasorelaxation in this model have been associated with reduced levels of NO bioactivity and increased generation of superoxide and/or peroxynitrite anions (McIntyre et al., [@B23], [@B22]; Kerr et al., [@B15]; Ma et al., [@B21]; see Bauersachs and Widder, [@B2] for review). As such, a cohort of HSFD SHR-SP was established as a model of cardiovascular disease associated with chronic oxidative stress in this study. Male SHR-SPs (*n* = 75) were obtained from Charles River Laboratories, Inc. (Kingston, NY, USA) and maintained on a normal powdered rodent diet (Lab Diet 5001, PMI Nutrition International, LLC, St. Louis, MO, USA) and tap water *ad libitum*. A subgroup of animals (*n* = 45) was anesthetized with isoflurane and surgically implanted with radiotelemetry transmitters (PhysioTel PA-C40, Data Sciences International, St. Paul, MN, USA). The transmitter catheter was threaded through the femoral artery into the abdominal aorta. At 11--12 weeks of age, baseline blood pressure and heart rate were measured for 5 days (10 s recordings every 5 min) in normal caging, then rats were acclimated to metabolic caging for a minimum of 48 h before a basal 24 h urine sample and blood were collected. After baseline measures, rats were assigned to six groups (*n* = 8--14 per group) according to mean arterial pressure (MAP; telemetered rats only) and body weight: normal diet (ND) control, HSFD, HSFD + 0.1 mg/kg/day GSK2181236A, HSFD + 1.0 mg/kg/day GSK2181236A, HSFD + 0.3 mg/kg/day BAY 60-4552, and HSFD + 3.0 mg/kg/day BAY 60-4552. The ND group was maintained on normal chow and water throughout the study. The other groups received a fat-enriched rodent diet (24.5% fat, Zeigler Bros., Inc., Gardners, PA, USA) and a 1% NaCl drinking water solution *ad libitum* for 8 week (Willette et al., [@B35]). Rats displaying signs of morbidity which included piloerection, lack of grooming, persistent body weight loss, lethargy, or seizure/convulsions, were promptly euthanized. Treatments were administered in respective diets starting 1 week after the initiation of HSFD. Urine collections were repeated on weeks 2, 4, 6, and 8 and blood was sampled in the morning after each 24 h collection period for assessment of renal function. Plasma creatinine and urine sodium, microalbumin (MALB), and creatinine were ascertained using an AU640 Chemistry Analyzer (Olympus America, Inc., Center Valley, PA, USA). Plasma compound concentrations were determined as described above. During week 7, cardiac function and morphometry were evaluated via transthoracic echocardiography. Rats were anesthetized with isoflurane (2--4% induction and 1--3% maintenance). Two-dimensional gray scale images of the left ventricle were obtained in the short axis plane at mid-ventricle level and in the parasternal long axis plane using a GE Vivid 7 system (GE Medical Systems, Milwaukee, WI, USA) and stored as digital cineloops. Pulse wave Doppler recordings from the LV outflow were obtained to determine heart rate. All images were analyzed by a single observer using a GE EchoPac (GE Medical Systems, Milwaukee, WI, USA). LV volumes were calculated as $V = \frac{5}{6}(\text{LVA} \times \text{LVL)}$ where LVA is area of LV chamber from the short axis view and LVL is the LV length from the long axis view at end diastole and end systole. LV mass was calculated from two dimensional images using the area-length method (Lang et al., [@B19]). Analysis was performed on three to five cardiac cycles. On week 8, isoflurane anesthetized rats were euthanized via exsanguination. The thoracic aorta was excised for assessment of endothelial function as described below. Hearts were snap-frozen in liquid nitrogen and stored at −80°C for later analysis of gene expression changes associated with cardiac hypertrophy and fibrosis (see below for procedure details). Gene expression analysis of cardiac tissue ------------------------------------------ Cardiac gene expression was analyzed following chronic (7 week) BAY 60-4552 or GSK2181236A treatment in HSFD SHR-SP. Hearts were homogenized in Trizol and RNA was extracted using the RNeasy Plus Mini kit protocol (Qiagen, Valencia, CA, USA) with a 40 μL elution volume. RNA was quantified using a Nanodrop Spectrophotometer ND-1000 (Thermo Fisher Scientific, Wilmington, DE, USA) and converted to cDNA using the High Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Carlsbad, CA, USA). Taqman assays were performed using a 384-well plate format with individual primer-probes and Taqman Universal PCR Master Mix (Applied Biosystems) and run on the 7900 HT Fast Real-Time PCR System (Applied Biosystems). SDS 2.3 software (Applied Biosystems) was used to obtain raw *C*~t~ values with manual threshold set at 0.10. Array Studio software (version 3.6.2; OmicSoft Corporation, Cary, NC, USA) was used to normalize gene expression data, by analysis of covariance, to the housekeeper genes β-2-microglobulin (*B2m*) and peptidyl-prolyl cis-trans isomerase A (*Ppia*). No outliers were detected by means of principal component analysis. The following genes were analyzed: α-skeletal actin (*Acta1*), type 1 collagen-alpha 1 (*Col1a1*), type 3 collagen-alpha 1 (*Col3a1*), connective tissue growth factor (CTGF; *Ctgf*), matrix metalloproteinase 2 (MMP2; *Mmp2*), matrix metalloproteinase 9 (MMP9; *Mmp9*), α-myosin heavy chain (α-MHC; *Myh6*), β-myosin heavy chain (β-MHC; *Myh7*); atrial natriuretic factor (ANF; *Nppa*), brain-type natriuretic peptide (BNP; *Nppb*), cGMP-specific phosphodiesterase 5A (PDE5A; *Pde5a*), type 2 cGMP-dependent protein kinase (PKG2; *Prkg2*), and transforming growth factor beta 1 (TGF-β1; *Tgfb1*). Isolated artery vasodilatation ------------------------------ Male Wistar Kyoto (WKY; Charles River Laboratories, Inc., Raleigh, NC, USA) were anesthetized with inhaled isoflurane (5% in O~2~) and euthanized by exsanguination. Thoracic aorta was isolated, cleaned of adherent tissue, cut into 3

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u,v)$. Since $u\gamma$ and $v\gamma$ are computable by induction hypothesis, $s\gamma=@(u\gamma,v\gamma)$ is computable by computability property (iv). 3. $s=\lambda x . u$. By computability property (v), $s\gamma=\lambda x.u\gamma$ is computable iff $u\gamma\{x\mapsto v\}$ is computable for an arbitrary computable $v$. Let now $\gamma'=\gamma\cup\{x\mapsto v\}$. By definition of substitutions for abstractions, $u\gamma\{x\mapsto v\}=u\gamma'$, which is usually ensured by $\alpha$-conversion. By assumptions on $\gamma$ and $v$, $\gamma'$ is computable, and $u\gamma'$ is therefore computable by the main induction hypothesis. Since an arbitrary term $s$ can be seen as its own instance by the identity substitution, which is computable by computability property (iii), all terms are computable by the Main Lemma, hence strongly normalizing by computability property (i). The Recursive Path Ordering and Computability {#s:rpo} ============================================= In this section, we restrict ourselves to first-order algebraic terms. Assuming that the set of function symbols is equipped with an ordering relation $\geF$, called *precedence*, and a status function $stat$, writing $stat_f$ for $stat(f)$, we recall the definition of the recursive path ordering: \[d:rpo\] $s\gtrpo t$ iff 1. \[rposubt\] $s=f(\vect{s})$ with $f\in\F$, and $ u \displaystyle{\gerpo} t$ for some $u\in\vect{s}$ 2. \[rpoprec\] $s=f(\vect{s})$ with $f\in\F$, and $t=g(\vect{t})$ with $f\gtF g$, and $A$ 3. \[rpomul\] $s=f(\vect{s})$ and $t=g(\vect{t})$ with $f=_\F g\in\Mul$, and $\vect{s}~(\displaystyle{\gtrpo})_{mul}~ \vect{t}$ 4. \[rpolex\] $s=f(\vect{s})$ and $t=g(\vect{t})$ with $f=_\F g\in\Lex$, and $\vect{s}~(\displaystyle{\gtrpo})_{lex}~ \vect{t}$ and $A$ $$\mbox{where } A=\forall v\in\vect{t}. ~ s\gtrpo v \quad\mbox{ and }\quad s\gerpo t \mbox{ iff } s\gtrpo t \mbox{ or } s=t$$ We now show the well-foundedness of $\gtrpo$ by using Tait’s method. Computability is defined here as strong normalization, implying computability property (i). We prove the computability property: \(vii) Let $f\in\F_n$ and $\vect{s}$ be computable terms. Then $f(\vect{s})$ is computable. The restriction of $\succ_{rpo}$ to terms smaller than or equal to the terms in $\vect{s}$ w.r.t. $\succ_{rpo}$ is a well-founded ordering which we use for building an outer induction on the pairs $(f,\vect{s})$ ordered by $(>_\F, (\succ_{rpo})_{stat_f})_{lex}$. This ordering is well-founded, since it is built from well-founded orderings by using mappings that preserve well-founded orderings. We now show that $f(\vect{s})$ is computable by proving that $t$ is computable for all $t$ such that $f(\vect{s}) \succ_{rpo} t$. This property is itself proved by an (inner) induction on $|t|$, and by case analysis upon the proof that $f(\vect{s}) \succ_{rpo} t$. 1. subterm case: $\exists u\in\vect{s}$ such that $u \succ_{rpo} t$. By assumption, $u$ is computable, hence so is its reduct $t$. 2. precedence case: $t=g(\vect{t})$, $f>_\F g$, and $\forall v\in\vect{t}$, $s\succ_{rpo} v$. By inner induction, $v$ is computable, hence so is $\vect{t}$. By outer induction, $g(\vect{t})=t$ is computable. 3. multiset case: $t=f(\vect{t})$ with $f\in Mul$, and $\vect{s}(\succ_{rpo})_{mul} \vect{t}$. By definition of the multiset extension, $\forall v\in\vect{t},~\exists u\in\vect{s}$ such that $u\succeq_{rpo} v$. Since $\vect{s}$ is a vector of computable terms by assumption, so is $\vect{t}$. We conclude by outer induction that $f(\vect{t})=t$ is computable. 4. lexicographic case: $t=f(\vect{t})$ with $f\in Lex$, $\vect{s}(\succ_{rpo})_{lex} \vect{t}$, and $\forall v\in\vect{t},~s\succ_{rpo} v$. By inner induction, $\vect{t}$ is strongly normalizing, and by outer induction, so is $f(\vect{t})=t$. The well-foundedness of $\gtrpo$ follows from computability property (vii). The General Schema and Computability {#s:closure} ==================================== As in the previous section, we assume that the set of function symbols is equipped with a precedence relation $\geF$ and a status function $stat$. \[d:closure\] The *computability closure* $\CS(t=f(\vect{t}))$, with $f\!\in\!\F$, is the set $\CS(t,\emptyset)$, s.t. $\CS(t,{\cal V})$, with ${\cal V}\cap\Var{t}=\emptyset$, is the smallest set of typable terms containing all variables in ${\cal V}$ and terms in $\vect{t}$, closed under: 1. \[csubterm\] subterm of basic type: let $s\in\CS(t,{\cal V})$, and $u$ be a subterm of $s$ of basic type $\sigma$ such that $\Var{u}\subseteq \Var{t}$; then $u\in\CS(t,{\cal V})$; 2. \[cprecedence\] precedence: let $f\gtF g$, and $\vect{s}\in\CS(t,{\cal V})$; then $g(\vect{s})\in\CS(t,{\cal V})$; 3. \[crecursive\] recursive call: let $f(\vect{s})$ be a term such that terms in $\vect{s}$ belong to $\CS(t,{\cal V})$ and $\vect{t} (\lrps{}{\beta}\cup\gtsubt)_{stat_f} \vect{s}$; then $g(\vect{s})\in\CS(t,{\cal V})$ for every $g =_\F f$; 4. \[capplication\] application: let $s : \sigma_1\ra\ldots\ra\sigma_n\ra\sigma\in\CS(t,{\cal V})$ and $u_i:\sigma_i \in\CS(t,{\cal V})$ for every $i\in[1..n]$; then $@(s,u_1,\ldots,u_n)\in\CS(t,{\cal V})$; 5. \[cabstraction\] abstraction: let $s\in\CS(t,{\cal V}\cup\{x\})$ for some $x\notin\Var{t}\cup{\cal V}$; then $\lambda x . s \in\CS(t,{\cal V})$; 6. \[creduction\] reduction: let $u \in \CS(t,{\cal V})$, and $u\lrps{}{\beta\cup\gtsubt} v$; then $v\in \CS(t,{\cal V})$. We say that a rewrite system $R$ satisfies the *general schema* iff $$\mbox{$r\in\CS(f(\vect{l}))$ for all $f(\vect{l})\ra r\in R$}$$ We now consider computability with respect to the rewrite relation $\lrps{}{R}\cup\lrps{}{\beta}$, and add the computability property (vii) whose proof can be easily adapted from the previous one. We can then add a new case in Tait’s Main Lemma, for terms headed by an algebraic function symbol. As a

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ctxt "text-direction" msgid "From left to right" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1788 msgctxt "text-direction" msgid "From right to left" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1789 msgctxt "text-direction" msgid "Vertical, right to left (mixed orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1790 msgctxt "text-direction" msgid "Vertical, right to left (upright orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1791 msgctxt "text-direction" msgid "Vertical, left to right (mixed orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1792 msgctxt "text-direction" msgid "Vertical, left to right (upright orientation)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1823 #, fuzzy msgctxt "text-hint-style" msgid "None" msgstr "קײנע" #: ../libgimpbase/gimpbaseenums.c:1824 msgctxt "text-hint-style" msgid "Slight" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1825 msgctxt "text-hint-style" msgid "Medium" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1826 msgctxt "text-hint-style" msgid "Full" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1857 msgctxt "text-justification" msgid "Left justified" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1858 msgctxt "text-justification" msgid "Right justified" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1859 msgctxt "text-justification" msgid "Centered" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1860 msgctxt "text-justification" msgid "Filled" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1890 msgctxt "transfer-mode" msgid "Shadows" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1891 msgctxt "transfer-mode" msgid "Midtones" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1892 msgctxt "transfer-mode" msgid "Highlights" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1921 msgctxt "transform-direction" msgid "Normal (Forward)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1922 msgctxt "transform-direction" msgid "Corrective (Backward)" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1953 msgctxt "transform-resize" msgid "Adjust" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1954 msgctxt "transform-resize" msgid "Clip" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1955 msgctxt "transform-resize" msgid "Crop to result" msgstr "" #: ../libgimpbase/gimpbaseenums.c:1956 msgctxt "transform-resize" msgid "Crop with aspect" msgstr "" #: ../libgimpbase/gimpmetadata.c:951 #, c-format msgid "Can load metadata only from local files" msgstr "" #: ../libgimpbase/gimpmetadata.c:965 ../libgimpbase/gimpmetadata.c:1035 #, c-format msgid "Conversion of the filename to system codepage failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1022 #, c-format msgid "Can save metadata only to local files" msgstr "" #: ../libgimpbase/gimpmetadata.c:1084 #, c-format msgid "Invalid Exif data size." msgstr "" #: ../libgimpbase/gimpmetadata.c:1113 #, c-format msgid "Parsing Exif data failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1163 #, c-format msgid "Parsing IPTC data failed." msgstr "" #: ../libgimpbase/gimpmetadata.c:1211 #, c-format msgid "Parsing XMP data failed." msgstr "" #: ../libgimpbase/gimputils.c:219 ../libgimpbase/gimputils.c:224 msgid "(invalid UTF-8 string)" msgstr "" #: ../libgimpbase/gimputils.c:394 msgid "File path is NULL" msgstr "" #: ../libgimpbase/gimputils.c:403 ../libgimpbase/gimputils.c:414 msgid "Error converting UTF-8 filename to wide char" msgstr "" #: ../libgimpbase/gimputils.c:422 msgid "ILCreateFromPath() failed" msgstr "" #: ../libgimpbase/gimputils.c:459 #, c-format msgid "Cannot convert '%s' into a valid NSURL." msgstr "" #: ../libgimpbase/gimputils.c:487 msgid "Connecting to org.freedesktop.FileManager1 failed: " msgstr "" #: ../libgimpbase/gimputils.c:511 msgid "Calling ShowItems failed: " msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:258 #, c-format msgid "'%s' does not appear to be an ICC color profile" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:304 msgid "Data does not appear to be an ICC color profile" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:361 msgid "Could not save color profile to memory" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:578 msgid "(unnamed profile)" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:620 #, c-format msgid "Model: %s" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:629 #, c-format msgid "Manufacturer: %s" msgstr "" #: ../libgimpcolor/gimpcolorprofile.c:638 #, c-format msgid "Copyright: %s" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:24 msgctxt "color-management-mode" msgid "No color management" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:25 msgctxt "color-management-mode" msgid "Color-managed display" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:26 msgctxt "color-management-mode" msgid "Soft-proofing" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:57 msgctxt "color-rendering-intent" msgid "Perceptual" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:58 msgctxt "color-rendering-intent" msgid "Relative colorimetric" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:59 msgctxt "color-rendering-intent" msgid "Saturation" msgstr "" #: ../libgimpconfig/gimpconfigenums.c:60 msgctxt "color-rendering-intent" msgid "Absolute colorimetric" msgstr "" #. * #. * SECTION: gimpcolorconfig #. * @title: GimpColorConfig #. * @short_description: Color management settings. #. * #. * Color management settings. #. * #: ../libgimpconfig/gimpcolorconfig.c:52 msgid "How images are displayed on screen." msgstr "" #: ../libgimpconfig/gimpcolorconfig.c:55 msgid "The color profile of your (primary) monitor." msgstr "" #: ../libgimpconfig/

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3-cells-08-01417} --------------------------------------------------------------------------------------------------------------------------------------------------------------- The data above clearly implies a causative role for mtROS in facilitating RSV infectious virus production. To test this formally, we decided to test whether blocking mtROS generation during RSV infection could limit RSV infection, as previously done, using the mtROS scavenger MitoQ \[[@B19-cells-08-01417]\]. Wild-type and KO cells were infected with RSV (MOI 1) and then treated with MitoQ at different times p.i., prior to cell lysis and subsequent quantitation of viral replication (qPCR) and infectious virus production (plaque assay) ([Figure 5](#cells-08-01417-f005){ref-type="fig"}). Results were unequivocal, showing significant (*p* \< 0.001) reduction of both viral replication and infectious virus production in both wild-type and KO cells in the presence of MitoQ. Treatment with MitoQ from 8 h p.i. had essentially the same effect in both lines, leading to \>10- and \>100-fold lower levels of RSV genomes and infectious virus titer, respectively ([Figure 5](#cells-08-01417-f005){ref-type="fig"}A,B). MitoQ treatment from 18 h had a less profound effect, but still significantly (*p* \< 0.001) reduced RSV genomes and the infectious virus titer by \~2- and almost 100-fold, respectively ([Figure 5](#cells-08-01417-f005){ref-type="fig"}A,B). As already indicated, HEK293T cells are an accepted infectious model for RSV \[[@B26-cells-08-01417],[@B27-cells-08-01417],[@B28-cells-08-01417]\]; our previous work with cells of the A549 human alveolar epithelial line, as well as primary human bronchiolar epithelial cells, indicated clear effects of RSV infection on mitochondrial respiratory activity and mtROS production \[[@B19-cells-08-01417]\], closely paralleling those observed here for HEK293T cells. We were keen to establish the relevance of the results here to other models of infection, such as A549 cells, with respect to protection by MitoQ against infection, over a longer, more physiological course of infection. We infected A549 with RSV for up to 8, 12, 24, and 48 h and added MitoQ for the last 8 h in each case ([Figure 6](#cells-08-01417-f006){ref-type="fig"}). The results show that an 8 h addition of MitoQ is able to significantly (*p* \< 0.001) suppress RSV replication ([Figure 6](#cells-08-01417-f006){ref-type="fig"}A) and infectious virus production ([Figure 6](#cells-08-01417-f006){ref-type="fig"}B), even at late stages of infection (i.e., 40 h p.i.); strikingly, 8 h treatment with MitoQ 40 h p.i. could still reduce infectious virus production almost 100-fold. To confirm that MitoQ's effects in this context are not through impacting cell viability, we assessed the release of the cytosolic enzyme lactate dehydrogenase (LDH) into the culture medium, indicative of cell death ([Figure A1](#cells-08-01417-f0A1){ref-type="fig"} in [Appendix A](#app2-cells-08-01417){ref-type="app"}). None of the MitoQ concentrations used significantly increased LDH release compared to that of controls in either the absence or presence of RSV infection, confirming that MitoQ is not cytotoxic; this is entirely consistent with other studies \[[@B19-cells-08-01417]\], with toxicity also shown to be absent in animal models and humans \[[@B34-cells-08-01417],[@B35-cells-08-01417],[@B36-cells-08-01417],[@B37-cells-08-01417],[@B38-cells-08-01417]\]. Overall, the results underline the relevance of the results here, with respect to the key role of mitochondrial Complex I in RSV infection to the development of anti-RSV therapies, with MitoQ of great potential as a viable option to treat established RSV infection (see Discussion). 4. Discussion {#sec4-cells-08-01417} ============= This is the first study to use KO cells to establish the importance of mitochondrial complex I in RSV infection. Deficiency of either of the specific complex I proteins, NDUFA10 and NDUFB10, that are integral to electron transport and Complex I assembly \[[@B21-cells-08-01417],[@B39-cells-08-01417],[@B40-cells-08-01417]\] results in elevated mtROS levels, compared to wild type ([Figure 4](#cells-08-01417-f004){ref-type="fig"}), and enhanced virus production ([Figure 3](#cells-08-01417-f003){ref-type="fig"}B). This is in stark contrast to the knock-out of other mitochondrial proteins, such as non-complex I protein TMEM261 or complex I component NDUFB4, which has more peripheral roles in super complex formation \[[@B31-cells-08-01417],[@B32-cells-08-01417],[@B41-cells-08-01417]\]; in these cases, lack of expression does not impact mtROS levels ([Figure 4](#cells-08-01417-f004){ref-type="fig"}), and RSV virus production is essentially normal ([Figure 3](#cells-08-01417-f003){ref-type="fig"}B). It is significant in this context that NDUFB10 deficiency has previously been associated with increased mtROS and compromised mitochondrial respiration \[[@B31-cells-08-01417],[@B42-cells-08-01417]\], while mutations in NDUFA10 have been found in mitochondrial disorders, such as Leigh disease \[[@B41-cells-08-01417],[@B42-cells-08-01417],[@B43-cells-08-01417]\]. Future studies could include studying viral growth kinetics in Complex I KO cells to elucidate the precise mechanism by which reduced mtROS favors RSV virus production. It is known that RSV infection interferes with many key cellular functions, but many of these appear to relate, as in the present study, to host cell mitochondria. Unbiased proteomic studies in RSV-infected cells, for example, reveal a large-scale impact on the abundance of a number of mitochondrial proteins, including complex I proteins, as well as voltage-dependent anion channel proteins, mitochondrial antioxidant enzymes, and the prohibitin subunits that play roles in regulating mitochondrial morphology, distribution, and biogenesis \[[@B44-cells-08-01417],[@B45-cells-08-01417],[@B46-cells-08-01417]\]. RSV's non-structural (NS) proteins are known to degrade signaling proteins required for interferon induction or response pathways early in infection \[[@B17-cells-08-01417]\]; such activity requires the formation of a NS-associated degradative complex on the mitochondria in a mitochondrial antiviral signaling adaptor (MAVS)-dependent manner \[[@B17-cells-08-01417]\]. It seems clear that the host cell mitochondria are a key target of RSV action, consistent with our recent report documenting that RSV infection induces a staged redistribution of mitochondria concomitant with compromised mitochondrial respiration and enhanced mtROS production in A549 human alveolar epithelial cells \[[@B19-cells-08-01417]\]; that these effects on mitochondria enhance viral pathogenesis \[[@B17-cells-08-01417],[@B19-cells-08-01417]\] further supports the idea that host cell mitochondria are a key target of RSV action. Our results here indicate for the first time that mitochondrial Complex I is central to this and the effects on decreased mitochondrial respiration and enhanced mtROS levels in particular \[[@B19-cells-08-01417]\]; that reduced Complex I activity leading to decreased mitochondrial respiration and increased mtROS favors RSV infection implicates Complex I as a key target of RSV in infected cells (see model in [Figure 7](#cells-08-01417-f007){ref-type="fig"}), making Complex I a potential therapeutic target for anti-RSV intervention strategies. Importantly in this context, the mtROS scavenger, MitoQ, can limit RSV infection, even in complex I-deficient cells ([Figure 5](#cells-08-01417-f005){ref-type="fig"}), confirming MitoQ's utility as a viable therapeutic to combat RSV in the future (see also \[[@B19-cells-08-01417]\] and below). The study here uses HEK293T cells/KO derivatives thereof as the infectious model to establish the key role of Complex I in the impact of RSV infection on mitochondrial function. We show that RSV infection strongly impacts mitochondrial respiratory function, leading to elevated mtROS production, and that the mtROS scavenger, MitoQ, in reducing mtROS in infected cells, can lead to reduced RSV replication and virus production. This aligns perfectly with our previous study \[[@B19-cells-08-01417]\], using more physiological models of RSV infection, including A549 human alveolar epithelial cells and primary human bronchiolar epithelial cells, where RSV infection strongly depresses mitochondrial respiratory function and elevates mtROS levels, which can be prevented with MitoQ. We also show that MitoQ protects against RSV here, even when added 40 h post-infection ([Figure 6](#cells-08-01417-f006){ref-type="fig"}), implying that MitoQ can be effective in reducing the viral load, even in an established RSV infection. We have previously

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<bddebian> Sure, give me a minute <bddebian> Shit, is revu down? <tonyyarusso> yes <bddebian> grr <tonyyarusso> grr indeedy <bddebian> Heya Hobbsee <LaserJock> tonyyarusso: dude it's still buiding <tonyyarusso> LaserJock: Ah! nvm me then :) * tonyyarusso falsely assumes all of you cool people have magical machines that build in five minutes or less...or something <bddebian> heh, I wish <Hobbsee> heya bddebian <ajmitch> tonyyarusso: you're funny <tonyyarusso> :) <Hobbsee> tonyyarusso: i wish <Hobbsee> tonyyarusso: although it does help to be able to ssh to fast machines. <tonyyarusso> Hobbsee: yeah <ajmitch> Hobbsee: you mean your laptop still isn't fast enough? <Hobbsee> ajmitch: other machines are faster. *shrugs* <Hobbsee> ajmitch: it's more the fact that it doesnt have a local mirror. <Hobbsee> ajmitch: so i dont have to wait ages for things to download * ajmitch doesn't have anywhere fast to build <bddebian> Well wtf.. <Hobbsee> ajmitch: aurora's not too bad, either. <ajmitch> faster connectivity than what I have <imbrandon> gah i need to make some more cash this month to get my home "network+mirror" back running <imbrandon> and get of my lazy bum and redo my website <ajmitch> heh <ajmitch> find a real job? :) <imbrandon> :) <Hobbsee> heh :) <Hobbsee> imbrandon: were you coming to boston, btw? <imbrandon> Hobbsee: most likely <Hobbsee> awww <Hobbsee> pity <imbrandon> ? * imbrandon feels loved <ajmitch> haha <imbrandon> :) <imbrandon> trying to get my wife into FL/OSS too <imbrandon> hehe <ajmitch> good luck with that <imbrandon> she actualy is kinda, in that she dosent use anything else but i mean contributing too <Hobbsee> bah. someone has good planning <Hobbsee> the linux thingy on today is when half of the second year comp students have their mandatory tutes. <Hobbsee> when that's a group that htey're targetting <LaserJock> tonyyarusso: argg, I don't think I have time to finish kompozer , it looks good to me <Hobbsee> LaserJock: you suck. <Hobbsee> LaserJock: that is all. <LaserJock> :p <Hobbsee> ajmitch: you suck more. <LaserJock> I'll be back <Hobbsee> hahahahahaha <Hobbsee> coward. <tonyyarusso> heh <tonyyarusso> Well, that's what, a + 1/2 ? <imbrandon> hrm anyone ever made a homebrew computer ? <imbrandon> seems like there is sparce info on it <imbrandon> only from the early 80's <StevenK> What do you mean homebrew? <imbrandon> like 8088 / z80 / 8086 breadboard comp <StevenK> At this point, people seem more concerned with stuffing Pentium III's into z80 boxes <imbrandon> heh , i stuffed a c7 into a c64 box :) <StevenK> c7 <StevenK> Gah <StevenK> c7's don't count. :-P <imbrandon> although a 6502 from a c64 or a apple 1 would be a cool homebrew too <tonyyarusso> bddebian: how's your build coming? <guest22> Hi. Can someone explain why revu.tauware.de is down again? * tonyyarusso is selling a C64-SX <tonyyarusso> guest22: I don't think anyone knows yet. <Hobbsee> tonyyarusso: siretart might be doing the machine change over today <imbrandon> -sx ? <tonyyarusso> Hobbsee: ooh, that would make sense <tonyyarusso> imbrandon: portable <imbrandon> how much ? <StevenK> "Portable" you say <tonyyarusso> imbrandon: http://minneapolis.craigslist.org/sys/406011461.html <imbrandon> c64 were pretty protable anyhow <StevenK> What does protable mean? * StevenK hides <tonyyarusso> Althought the link on the posting seems down :( <tonyyarusso> imbrandon: http://en.wikipedia.org/wiki/Commodore_SX-64 for a pic <imbrandon> ahh craigs list , i love craigs list <imbrandon> tonyyarusso: yea i rember it now <tonyyarusso> The keyboard snaps on as a cover over the monitor on the front of the computer, and the prop leg serves as a carrying handle. <StevenK> 10KGs?! <bddebian> tonyyarusso: I still can't get on REVU <imbrandon> if not more <StevenK> That's not so much portable. <imbrandon> tonyyarusso: i wouldent mind buying it but thats too much of a premium for me, if it dosent sell hit me up <tonyyarusso> bddebian: Nor can anyone else. LaserJock was just working from http://www.tonyyarusso.com/kompozer/ manually. <tonyyarusso> imbrandon: We haven't had a response yet, so you could just make an offer (use the cl link - it's my dad) * StevenK teaches bddebian to read scrollback. <imbrandon> k <imbrandon> i will this evening, i'm lazy and dont wanna open gmail atm heheh <imbrandon> but i got it bookmarked <tonyyarusso> lol, that is lazy <imbrandon> StevenK: and btw the c7 was 1.5GHZ ;) <StevenK> imbrandon: You want to use the SX as a desktop? :-P <imbrandon> hahaha well i do have a c64 2400 baud modem <imbrandon> i used to get on bbs's with * tonyyarusso wonders how much work it would take to get Linux running on it <imbrandon> tonyyarusso: one floppy <imbrandon> there is a c64 linux distro <tonyyarusso> imbrandon: Someone's done that port? <tonyyarusso> sweet <imbrandon> LUnix <tonyyarusso> fun <imbrandon> LNG is an operationg system primarly for the good old Commodore64 home-computer. There also is a native version for the successor Commodore128. Ports to other 6502/6510 driven 8Bit Computers are possible but not yet started. LUnix started in 1993 and reached the internet in 1994. In 1997 LUnix0.1 was rewritten from scratch, the result is LNG. <imbrandon> http://lng.sourceforge.net/ <bddebian> Sorry I'm only half pay attention. I'll check it out in a bit <imbrandon> apple 1's were 6502 proc along with others of the time <ajmitch> Hobbsee: cruelty <Hobbsee> ajmitch: warranted, though. <tonyyarusso> bddebian: a short bit would be best, since we want to close up for NPFU, and this is the last one. <ajmitch> Hobbsee: not at all <Hobbsee> ajmitch: but i cant do interviews :P <ajmitch> yes you can <imbrandon> brb <Hobbsee> ajmitch: nope <Hobbsee> where would the fun in that be? <ajmitch> Hobbsee: did you get an email from laserjock asking you to? :) <Hobbsee> ajmitch: yes <ajmitch> excellent.... * ajmitch didn't :) * Hobbsee hits the forward button, then. <ajmitch> it's perfectly alright, I don't mind you doing the interview <bddebian> tonyyarusso: Building now your highness <tonyyarusso> bddebian: lol, awesome <

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is hard to categorize in both content and form, and that is a very good thing. One could say Jer3miah is more intimate with things Mormon than more official Mormon productions. For example, inherent in Mormonism is a deep-seated sense of history and a connectedness to past and future generations. The dramatic translation of those concepts within Jer3miah is cliff-hanging events that turn on genealogical information and on strange visitors invoking the ancient Nephite setting of the Book of Mormon. Like the embattled hosts within the more epic portions of the Mormon bible, Jeremiah finds himself facing secret combinations of evil. Yet Jer3miah has a more contemporary vibe than the costume drama Mormon mini-epics based on scripture. This is hosted on Vimeo and YouTube, and it channels the youth culture of the net generation. The prankster roommates and high-tech surveillance criss cross with Mormon folklore and scripture in a hybrid bound to simultaneously upset and spellbind various audiences. But the through-line for the series is character, and this gives the series authenticity despite its obviously experimental nature. Jeremiah must resolve his aching need for an orienting identity. Ironically, that is what Mormonism is all about. Latter-day Saints claim an eternal identity; however, the media productions of Mormonism are seldom about feeling all the more lost and endangered for having a spiritual and eternal identity. This series sits on the edge of Mormonism, taking its ideas of eternal progression and individual mission so seriously that the stakes are realized in human terms, with evil as present and potent a reality as God. The protagonist of Jer3miah fights with his heritage and destiny--almost as though he is director Jeff Parkin's doppleganger. Parkin (pictured here), a popular and outspoken film professor at Brigham Young University, has called for more authenticity in Mormon storytelling (see his February 2009 university-wide lecture,“Story and Authentic Messengers: Meditations on Film, Originality and Poisonous Art") . Jer3miah is Parkin's proof of concept. The series has made waves among Latter-day Saints precisely because he has chosen to make Mormonism central to the storytelling: LDS youth really do feel a sense of destiny, they really hear and follow spiritual promptings, and they really do get in trouble in the process. Following God is displayed as a dangerous prospect in Jer3miah; not because religion is a fraud, but precisely because it isn't. I have heard people preach that discipleship is an adventure, but the idea takes on a whole new dimension when Jeremiah--held hostage at gunpoint--must choose between his girlfriend's life and breaking a sacred oath. Believe me, atheists and anti-Mormons will hang on for the resolution of any of the series' many cliffhangers like this. Parkin's creation swims upstream against the well-established modes of Mormon media, but there is a confidence to the production, a palpable enthusiam echoed in the fanbase and the ancillary media filling out the series folklore. Not all of this will succeed, but more than enough already has. Parkin is testing the adequacy of new media for cinematic storytelling and for his own religion. It is a brave series for all of that, with good omens for coming seasons. Comments This is a smart analysis of the Jer3miah series. I wonder what your impressions are of how technology is used in the Jer3miah narrative? While for the most part it is the bad guys that use smart phones, bluetooths, satellite imagining, and high-tech computers to advance their evil, there is a moment in episode 4 where Jeremiah gets a text message to his cell phone that is a message from God (or at least a message that God wants Jer3miah to hear)telling him he needs to essentially work to become trustworthy again to get the box back. I can't think of any other LDS examples of God communicating to man through text messaging. If there are some it is probably done in gist, but Jer3miah does it in all seriousness. Also, Jeremiah is often instructed and inspired to keep a record of his personal history, much like the people in the Book of Mormon, only with Jeremiah it is with a modern digital video camcorder. I bring this up because you are the first person I have seen that has really touched on Jer3miah's obvious and important ties to technology both in distribution and content and I was wondering what your extended thoughts on it were. Very good analysis of the show. I've kept up with the Buzz surrounding Jer3miah, and it's refreshing to read an editorial that doesn't merely state what the show "tries to be," but actually gives an insightful, and--from what I can tell--accurate explanation of what the show actually does. The show is definitely experimental, as you observed, not only in the way it delivers a Mormon Story, but the means by which it delivers the story, through a website, as well as with a parallel Alternate Reality Game that adds depth to the characters; and to the mystery. It's truly an innovative endeavor, and though not all of it's reviews are positive, one must, at least, acknowledge all that it has accomplished. It's been a tremendous effort, not only by Jeff Parkin, but the other faculty and students that worked so diligently to pull off the production demands of a weekly web-based show. Yes - great post! This is a great series and an incredible endeavor. I enjoyed the way you paralleled the series with the reality of living Church doctrine. I also loved the idea of following promptings and working our way through life as being an adventure. Jeff, Jared, and everyone have helped tell a great story with a Mormon essence. It's been a treat to see everything unfold.Survival and histological resolution of fibrosis in patients with autoimmune chronic active hepatitis. Survival and long-term clinical and histological outcome were assessed retrospectively in 33 patients treated for autoimmune chronic active hepatitis. The Mayo Clinic treatment criteria were met by 30 of 33 patients and histological signs indicating nodular fibrosis and/or cirrhosis were present in 16 of 33 (48%). An overall 10-year survival rate of 90% was found by life-table analysis. This was not significantly different from matched controls (92%). Paired liver biopsies revealed that 16 of 28 (57%) patients improved their fibrosis/cirrhosis category whereas none progressed in a follow-up biopsy performed a median of 49 months later. Furthermore, liver biopsy showed improvement in 9 of 14 patients with initial nodular fibrosis/cirrhosis and resolution of nodulation. When a semi-quantitative scoring system was applied, the median fibrosis score improved significantly. A key factor intervening in the progression of fibrosis seemed to be the reduction of inflammatory activity as a result of immunosuppressive treatment. We conclude that fibrosis may be resolved in autoimmune chronic active hepatitis following protracted and effective treatment which is initiated early in the course of the disease.Platypnoea-orthodeoxia syndrome post laparoscopic surgery in a patient with a patent foramen ovale. Platypnoea-orthodeoxia syndrome has the pathognomonic clinical findings of dyspnoea and arterial hypoxaemia relieved by recumbency. We report on a patient who presented with platypnoea-orthodeoxia syndrome post laparoscopic surgery. Platypnoea-orthodeoxia syndrome is an important diagnosis to consider when investigating hypoxia without an obvious cause.Film roll accumulating devices for forming a filmstrip into a film roll are typically used in the film take-up chamber of a camera or in a film cassette. As discussed in prior art U.S. Pat. No. 3,057,573, patented Oct. 9, 1962, it is desirable for the film take-up chamber of a camera to be expandable to accommodate enlargement of the film roll as additional film is fed into the take-up chamber. Similarly, it is desirable for the supply chamber of a film cassette to be expandable to accommodate enlargement of the film roll as additional film is fed into the supply chamber. Prior art U.S. Pat. No. 3,718,301, patented Feb. 27, 1973, discloses a film cassette in which an arcuate pressure shoe is slidably mounted in the cassette housing, and a spring urges the pressure shoe toward a front cover of the cassette housing. When the cartridge housing does not contain any film, the arcuate pressure shoe is relatively close to the front cover. When a filmstrip is first fed into the cartridge housing, the arcuate pressure shoe guides the filmstrip into a film roll having a small inside diameter. The pressure shoe is forced backwardly against the urging of the spring as the outside diameter of the film roll is increased by further feeding the filmstrip into the cartridge housing. Thus, the centerpoint or the center axis of the film roll shifts to accommodate enlargement of the film roll.Q: Can my asp.net dll's or pages can be affected by virus living in my pc Just curious to know that if my PC is infected with a Trojan or any other virus, is it possible that my website will be infected along with that I have made up in asp.net with visual studio 2008. I am not sure that it is the right place to put this question or shall I have to put it to https://stackapps.com/ or any other site linked to stackoverflow. But anyhow it is very important for me to know the answer. Because one gentleman report me about the infection of Jquery-

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James Bradley Thayer, _The Origin and Scope of the American Doctrine of Constitutional Law_ , 7 HARV. L. REV. 129 (1893); West Virginia State Bd. of Educ. v. Barnette, 319 U.S. 624, 670 (1943) (Frankfurter, J., dissenting); BICKEL, LEAST DANGEROUS BRANCH, _supra_ note 49, at 16. _Cf._ Michael Stokes Paulsen, _Does the Constitution Prescribe Rules for Its Own Interpretation?_ , 103 NW. U. L. REV. 857 (2009). RICHARD A. POSNER, LAW, PRAGMATISM AND DEMOCRACY 234–47 (Harvard Univ. Press 2003). _See_ Gottlieb, _Compelling Governmental Interests_ , _supra_ note 68. _Compare_ Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 726–50 _with_ Gottlieb, _Compelling Governmental Interests_ , _supra_ note 68. _See also_ POWELL, MORAL TRADITION, _supra_ note 11, at 182–292; Robin L. West, _Are There Nothing but Texts in this Class? Interpreting the Interpretive Turns in Legal Thought_ , 76 CHI-KENT L. REV. 1125 (2000); Robin West, _Progressive and Conservative Constitutionalism_ , 88 MICH. L. REV. 641 (1990). FRIEDRICH NIETZSCHE, THUS SPOKE ZARATHUSTRA (Barnes & Noble Classics 2007) (1883–1885). See San Antonio Indep. Sch. Dist. v. Rodriguez, 411 U.S. 1, 49–50 (1973). _See, e.g._ , Clarence Thomas, _The Higher Law Background of the Privileges or Immunities Clause of the Fourteenth Amendment_ , 12 HARV. J. L. & PUB. POL'Y 63 (1989). WOOD, CREATION OF THE AMERICAN REPUBLIC, _supra_ note 46, at 24–25, 167–68. _See_ Locke, SECOND TREATISE, _supra_ note 34. Michael H. v. Gerald D., 491 U.S. 110, 163n (1989). _See_ POWELL, MORAL TRADITION, _supra_ note 11 at 182–292. _See_ Feinberg, _Civil Disobedience_ , _supra_ note 33, 2 HUMAN. IN SOC'Y at 45–58; _but see_ William Van Alstyne, _Clashing Visions of a "Living" Constitution: Of Opportunists and Obligationists_ , 2010–11 CATO SUP. CT. REV. 13. On the source of moral obligations, _see_ DAVID HUME, AN ENQUIRY CONCERNING THE PRINCIPLES OF MORALS 125–36 (1751) (Open Court Pub. Co. 1966). _See also_ James E. Fleming, _Living Originalism and Living Constitutionalism as Moral Readings of the American Constitution_ , 92 B.U. L. REV. 1171 (2012). Moore v. East Cleveland, 431 U.S. 494, 503 (1977). _Compare_ Exxon Shipping Co. v. Baker, 554 U.S. 471 (2008) _with id._ at 515 (Scalia, J., concurring), _and_ Pac. Mut. Life Ins. Co. v. Haslip, 499 U.S. 1, 25 (1991) (Scalia, J., concurring in the judgment). Dep't of Revenue v. Davis, 553 U.S. 328 (2008); United Haulers Ass'n v. Oneida-Herkimer Solid Waste Mgmt. Auth., 550 U.S. 330, 344, 342 (2007); Edmonson v. Leesville Concrete Co., 500 U.S. 614 (1991). Pac. Mut. Life Ins. Co. v. Haslip, 499 U.S. 1, 25 (1991) (Scalia, J., concurring in the judgment). Souter in Washington v. Glucksberg, 521 U.S. 702, 766 (1997) (Souter, J., concurring). Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 726. See Lawrence B. Solum, _The Unity of Interpretation_ , 90 B.U. L. REV. 551, 567–78 (2010); Andrew B. Coan, _The Irrelevance of Writtenness in Constitutional Interpretation_ , 158 U. PA. L. REV. 1025 (2010). Coan, _The Irrelevance of Writtenness_ , _supra_ note 90, 158 U. PA. L. REV. at 1090. _See_ Ran Hirschl, _The New Constitutionalism and the Judicialization of Pure Politics Worldwide_ , 75 FORDHAM L. REV. 721, 752 (2006); Richard Albert, _Why Judicial Review: A Preliminary Typology of Scholarly Arguments_ , INT'L J. CONST. L. BLOG, Mar. 25, 2013, http://www.iconnectblog.com/2013/03/why-judicial-review. _See_ Bond v. United States, 131 S. Ct. 2355, 2367 (2011); Alden v. Maine, 527 U.S. 706, 736 (1999); _and compare_ Nat'l League of Cities v. Usery, 426 U.S. 833 (1976) _with_ Garcia v. San Antonio Metro. Transit Auth., 469 U.S. 528 (1985). _Cf._ Paulsen, _Rules for Its Own Interpretation_ , _supra_ note 73. Stern v. Marshall, 131 S. Ct. 2594 (2011); Arizona Christian Sch. Tuition Org. v. Winn, 131 S. Ct. 1436 (2011); _and cf._ McDonald v. City of Chicago, 130 S. Ct. 3020, 3095n (2010) (Stevens, J., dissenting). U.S. CONST., art. I, sec. 2, par. 3. U.S. CONST., art. II, sec. 1,pars. 2–4. U.S. CONST., Amends. XIII, XIV, XV, XIX, XXIV and XXVI. CHARLES L. BLACK, JR., STRUCTURE AND RELATIONSHIP IN CONSTITUTIONAL LAW (Louisiana State Univ. Press 1969); _and see_ Bobbitt, _Constitutional Fate_ , _supra_ note 21, 58 TEX L. REV. at 721–25. _See_ Wesberry v. Sanders, 376 U.S. 1, 8 (1964). United States v. Carolene Products Co., 304 U.S. 144, 152n. 4 (1938). BLACK, STRUCTURE AND RELATIONSHIP, _supra_ note 99. Stephen E. Gottlieb, _Introduction: Overriding Public Values_ , _in_ PUBLIC VALUES IN CONSTITUTIONAL LAW 1 (Univ. Michigan Press, Stephen E. Gottlieb, ed. 1993). Abraham Lincoln, Gettysburg Address, Nov. 19, 1863. _See_ JAMES KENT, COMMENTARIES ON AMERICAN LAW, vol. 2, at 338 (Blackstone Publishing Co., William M. Lacy, ed. 1889); SIR EDWARD COKE, THE REPORTS OF SIR EDWARD COKE, vol. 6, at 280 (J. Butterworth and Son, John Henry Thomas and John Farquhar Fraser, eds. 1826); CHARLES VINER, A GENERAL ABRIDGMENT OF LAW AND EQUITY, ALPHABETICALLY DIGESTED UNDER PROPER TITLES; WITH NOTES AND REFERENCES TO THE WHOLE, vol. 15, at 534–35 (G. G. J. & J. Robinson, 1793); American Print Works v. Lawrence, 21 N.J. Law. (3 Zab.) 248, 258–59 (1847); Respublica v. Sparhawk, 1 U.S. (Dal.) 357, 362–63 (Pa. 1788). Alexander Hamilton, _The Vindication [of the funding system] No. III_ , _in_ SELECTED WRITINGS AND SPEECHES OF ALEXANDER HAMILTON 331, 333 (American Enterprise Inst. for Pub. Pol'y Research, Morton J. Frisch, ed. 1985). WOOD, CREATION OF THE AMERICAN REPUBLIC, _supra_ note 46, esp. the final chapter, _The Federalist Science of Politics_. Kathleen Sullivan, _Categorization, Balancing and Government Interests_ , in PUBLIC VALUES IN CONSTITUTIONAL LAW, _supra_ note 103, at 241. For the previous Court, see GOTTLIEB, MORALITY IMPOSED, _supra_ note10, at 29. On trying to build

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�漫漫涯涘。沒湫湫名溺沍涸名漫漶潦潦。 Cao's rhapsody insistently repeats one radical, thus luring the readerly mind away from the automatic connection between shape and meaning toward a graphic appreciation. Through repetition, it seems to achieve an analytical apperception, a pattern recognition on the level of character elements, and not, as in the normal reading process, on the level of the overall gestalt of a character that a reader then connects to a memory of meaning and sound. Cao's text displays a graphic variation of Roman Jakobson's definition of the poetic function of language: the application of paradigmatic criteria on a syntagmatic level. According to Jakobson, poetic word choice is dictated by contiguity with other signs, through either similarity or contrast. This becomes especially visible in the structural features of highly regulated literary forms, for instance, meter, rhyme, or alliteration in poetry. Jakobson's theory of the poetic function of language, developed in the cultural context of a phonetic script, tends to highlight phonetic repetition or contrast. However, Jakobson's theory is equally valid from a graphic point of view. In the context of sinographic texts, attention to graphic as well as phonetic repetition makes particular sense, because the modular character of the sinographs allows for the repetition of components on the level of the written sign in contrast to alphabetic or other phonetic scripts. What might be a largely unconscious process in the creation of Chinese texts, namely, that character choice is prompted by previously selected characters with similar elements or, on a phonetic level, similar pronunciation, comes to the forefront as a visible strategy in Cao's radical design. Cao's work draws attention to the materiality of language, illustrating with zeal (and some exaggeration) Roman Jakobson's definition of the poetic function of language, namely, the influence of syntagmatic combination on the selection of words or, in Cao's case, single characters. But the radical that Cao's rhapsody underlines stands out from other (sino)graphic components: not only does it have a meaning-bearing function, but it also turns out to be mimetic in character—after all, the three dots, or drops, of the radical visualize the idea of water and invoke the "view" or "contemplation" of the waves that the title promises. In other words, radical sinographic design, such as the repetition of radicals in Cao's text, can foreground a very limited aspect of the _techne_ of character construction, one that, though potentially analytical, might ultimately return to a mimetic myth of Chinese writing in a slightly updated form. Another type of experiment with the components of the graphic system of Chinese achieves its cultural anchorage by emphasizing meaning as well as _graphe_. This is the case in experiments that have a neographic, rather than a pseudographic, thrust; they avail themselves of ideographic principles to craft new characters whose meaning—though not part of the lexicalized vocabulary—is easy to guess. For instance, the mainland poet Yang Lian 楊煉 uses a neograph as the title of one of his most famous works, the long poem _Yi_ , published in 1989, a kind of _Yijing_ 易經 ( _Book of Changes_ ) for our times. Yang Lian himself calls the title of the work, _Yi_ , a "noncharacter" ( _wu zi zhi zi_ , 無字之字), and likens it on several occasions to Xu Bing's pseudographs. Unlike Xu Bing's graphic experiment, Yang Lian's newly crafted Chinese character is not devoid of meaning. Instead, the poet takes great pains to lexicalize it. The graph comes with its own pronunciation ( _yi_ ) and tone (first tone), as the poet indicates carefully at the beginning of his text, both in Pinyin transcription and in the older method of transliteration through two Chinese characters, in which the first indicates sound and the second tone, which is used mainly in commentaries on classical texts. Consisting of two pictographs, "人" ( _ren_ , "human being") and "日" ( _ri_ , "sun"), in a style reminiscent of ancient Chinese seal script, Yang's title combines two character (which are also radicals) to form a new one. As the connection of heaven and man, Yang Lian's _yi_ forms a counterpart to the _yi_ 易 of the _Yijing_. _Yi_ in the title of the classic is most commonly translated as "change," but its exegetes also point to the pictographic substratum of the character: a combination of "日" and "勿" (as an alternative form of _wu_ 物 or "animated thing"). Rather than a radical commentary on Chinese writing, Yang Lian's neographic intervention uses ideography, the combination of two pictographs, one of the six ways of character formation, the _liu shu_ 六書. The creative resources of the sinographic script subtly reinforce the meaning of the work as a whole: a repositioning of man in the universe. Rather than challenging the sinographic regime and its tradition, Yang Lian's neographic character displays the adaptability of Chinese writing, its openness to new meanings and ideas. By drawing on the Chinese tradition of the commentary, with its set ways of defining rare words, applied here to a neographism, Yang Lian's textual move inscribes itself within the long tradition of Chinese culture. However, by aligning himself with Xu Bing's graphic experiments, Yang Lian also advocates for a flexible, not slavish, use of Chinese tradition in order to enlarge its textual archive and enrich its sinographic medium. Whereas Yang Lian desires his "noncharacter" to be readable and goes to great lengths to achieve this, the Taiwanese poet Chen Li 陳黎 engages in a poetic reflection on the unreadability of pseudographs. One of the poems of his collection _Light/Slow_ ( _Qing/man_ 輕/慢), published in 2009, "A Difficult Poem That Is Easy to Read" ("Yi shou rongyi du de nan shi" 一首容易讀的難詩) contains four lines of cryptic characters. At first glance, Chen Li's strange characters seem to exhibit their unreadability. Chen Li had created the pseudographic text first in his earlier collection _Worries and Freedom Well-Tempered_ ( _Kunao yu ziyou de pingjunlü_ 苦惱與自由的平均律) where it had appeared on its own, just designated as "A Love Poem" ("Qingshi" 情詩). Now, the last lines of the text are recontextualized, imagined as an opaque Chinese poem cherished by Pindar, the famously difficult poet of Greek antiquity: He liked to read a Chinese poem called "Love Poem" because this poem, so they say, was equally difficult to read irrespective of if it was translated into Greek or not At face value, the poem's new frame, especially with its reference to Pindar, emphasizes the strange link between pseudographs and translation. Since these signs are "fake," they are not in need of translation; they are as cryptic to native readers of Chinese as to somebody who reads and writes in ancient Greek, such as Pindar. As in the case of Xu Bing's _A Book from the Sky_ , the opacity of pseudographic text transcends the limits of specific languages and is thus universal. However, Chen Li's poem presents such a translation as an actual possibility, even though, of course, the absence of meaning, or the fact that meaning is transferred to graphic form, makes these signs unique to their specific script. These look-alike characters on the one hand do not need translation, but on the other are untranslatable, since no adequate way of translating, or, indeed, transgraphing, pseudo-Chinese into pseudo-Greek exists. For Chen Li, pseudographs cannot simply signify the absence of signification or the impossibility of translation. The very gesture of framing part of the former stand-alone text of "A Love Poem" in a subsequent work almost remedies an earlier oversight, or else embodies a sustained manipulation of the reader. In _Light/Slow_ , a part of Chen Li's poems that are commentaries on individual Chinese characters is dedicated to glossing some of the supposedly inexistent Chinese signs from "A Love Poem" and "A Difficult Poem That Is Easy to Read," even supplying information on their voicing in his notes to the poems. After presenting these Chinese characters to readers as supposedly unintelligible sinographics, Chen Li provides them with meaning and cultural context: many of these signs turn out to be rare characters or to belong to the vocabulary of regions or ethnicities at the margins of Chinese culture. Irrespective of the facticity or fiction of these glosses, they open up the system of the Chinese script once we can read these signs (or imagine that we are reading them) not simply as spurious play that merely reactivates the rules of character construction, but as the possibility of other uses of sinographic material at the margins of a linguistic system and its norms. In Chen Li's poem, graphic experimentation ultimately returns to the question of meaning, especially to the question of the connection between cultural meaning and graphic form.

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membrane than those from active colonies located farther to the south at Adélie Cove and Inexpressible Island at Terra Nova Bay (ANOVA, *F*~3~ = 41.8, *p* \< 0.001; [table 2](#RSOS172032TB2){ref-type="table"} and [figure 3](#RSOS172032F3){ref-type="fig"}). There was no difference in *δ*^15^N values between Cape Adare and Cape Hallett, or between Adélie Cove and Inexpressible Island. No differences in *δ*^13^C values occurred among all four sites (ANOVA, *F*~3~ = 1.2, *p* \> 0.32). Figure 3.Mean *δ*^13^C and *δ*^15^N isotope values from modern Adélie penguin egg membrane collected from four active penguin colonies in the Ross Sea. Samples from Cape Adare were collected in January 2005; all other samples were collected in January 2016. Error bars are one standard deviation. See the electronic supplementary material, table S1 for raw data. Table 2.Mean ± s.d. of stable isotope results of modern Adélie penguin egg membrane from four breeding colonies in the northern to central Ross Sea, Antarctica. (For each set of isotope values, shared letters (in superscript) indicate no significant differences in means (one-way ANOVA, *F*~3~ = 1.2, *p* \< 0.32 for *δ*^13^C, *F*~3~ = 41.8, *p* \< 0.001 for *δ*^15^N).)location*Nδ*^13^C (‰)*δ*^15^N (‰)Cape Adare5−25.0 ± 0.55^A^9.2 ± 0.38^A^Cape Hallett20−24.6 ± 0.55^A^9.1 ± 0.40^A^Adélie Cove15−24.6 ± 0.98^A^10.2 ± 0.27^B^Inexpressible Island21−24.3 ± 1.04^A^10.0 ± 0.30^B^ 4.. Discussion {#s4} ============== Our results suggest that Cape Adare, first occupied by breeding penguins at approximately 2000 BP \[[@RSOS172032C7]\] follows an expected colonization pattern with Ridley Beach completely occupied by approximately 1200 BP and remaining so today. Colonization of the upper terrace began by approximately 1700 BP with the most distant colonies to the south on this terrace occupied by approximately 1200 BP (based on median ages, [table 1](#RSOS172032TB1){ref-type="table"}), with at least some remaining active until approximately 800 BP. The relative brief occupation of these sites also is suggested by their relatively shallow (one level, or 5--8 cm) ornithogenic soils. Only the northern edge of this terrace overlooking Ridley Beach remains occupied today. Numerous other abandoned pebble mounds were located on the upper terrace at Cape Adare, but ground time was too limited in 2016 for additional sampling. We believe all of these sites, owing to their similar appearance on the surface, were colonized during the same sequence of occupation as S1--S5. If so, the large area of occupation on this terrace (approx. 0.78 km^2^, or similar to area on Ridley Beach at 0.80 km^2^; [figure 2](#RSOS172032F2){ref-type="fig"}) is conservatively estimated to have supported an additional approximately 200 000 breeding pairs of Adélie penguins at peak occupation. Thus Cape Adare, though currently one of the largest Adélie penguin colonies in Antarctica, was possibly up to twice as large by approximately 1200 BP than it is today and consisted of approximately 500 000 breeding pairs at that time. We hypothesize that this 'supercolony' (a penguin colony with greater than 500 000 nests) underwent continuous growth after initial colonization at approximately 2000 BP until approximately 800 BP when it began declining to its present size. What factors were driving the increase in this penguin 'supercolony' during this period? Other events in the Ross Sea at that time may help explain this hypothesized growth at Cape Adare. From 4000 to 2000 BP, the Scott Coast as well as other locations on Beaufort and Franklin Island were occupied by breeding penguins during a warm period known as the penguin 'optimum' \[[@RSOS172032C7],[@RSOS172032C11],[@RSOS172032C12]\]. The Scott Coast was completely abandoned after 3000--2000 BP, with the youngest site at Marble Point ([figure 1](#RSOS172032F1){ref-type="fig"}), probably owing to a cooling period that caused increased fast ice that blocked access to beaches along this coastline, preventing penguins from breeding there \[[@RSOS172032C12]\]. This fast ice in western McMurdo Sound persists well into the summer months today and the Scott Coast has remained abandoned by breeding penguins to the present. We hypothesize that colonization at Cape Adare began as the Scott Coast was being abandoned by approximately 2000 BP, signifying a large-scale movement of breeding penguins from the southern to the northern Ross Sea. Further, upwelling of Circumpolar Deep Water in the northern Ross Sea from the continental shelf break has maintained open water in the Ross Sea polynya near Cape Adare, along with the high marine productivity at the marginal ice zone \[[@RSOS172032C13],[@RSOS172032C14]\]. The northern Ross Sea and associated polynya have provided and continue to support large swarms of krill that in turn support large populations of breeding penguins that currently occur at Cape Adare, Cape Hallett (61 160 nests) and Coulman Island (19 437 nests) \[[@RSOS172032C6]\]. Though Cape Adare has been ice-free for thousands of years \[[@RSOS172032C15]\], Ridley Beach may not have been accessible to breeding penguins prior to 2000 BP owing to its low elevation, causing it to be either submerged at slightly higher sea level or too exposed to storm surges in the warming phase of the penguin optimum. Once the beach did become accessible, it was able to support increasing numbers of breeding penguins, especially with development of the higher-elevation ornithogenic mounds that currently transect the beach. Though the upper terrace could have been occupied prior to 2000 BP, older ornithogenic deposits have yet to be discovered and additional investigation is warranted. Stable isotope data also indicate that penguins at Cape Hallett and Cape Adare presently feed significantly more on krill than fishes, as indicated by lower *δ*^15^N values in egg membrane from these sites compared to similar samples from active colonies in the Terra Nova Bay and southern Ross Sea regions. Although the sample size of modern egg membrane from Cape Adare is small (*n* = 5), these results support an earlier study on modern penguin eggshell *δ*^13^C and *δ*^15^N from colonies in the southern Ross Sea compared with Cape Hallett to the north that indicated a more krill-based diet at this latter site \[[@RSOS172032C16]\]. While these studies on eggshell and membrane only represent diet of female penguins prior to egg laying, other dietary studies at modern and ancient colonies support these dietary differences between northern and southern colonies in the Ross Sea. For example, investigation of Adélie penguin diet at Cape Hallett, based on stomach flushing and contents \[[@RSOS172032C17]\], found that these penguins feed largely on krill during the guard stage of chick-rearing and prey increasingly on fishes as the season progresses. Satellite tracking of foraging penguins also revealed that most move to the continental shelf break. Moreover, stable isotope analyses of ancient penguin guano also suggest a diet based more on fishes in the southern Ross Sea during the Holocene \[[@RSOS172032C18]\] that persists with colonies on Ross Island today (colonies at Cape Royds, Bird and Crozier, [figure 1](#RSOS172032F1){ref-type="fig"}) \[[@RSOS172032C19]\]. Prey remains and otoliths from ornithogenic soils excavated at abandoned colonies on Ross Island also indicate that Antarctic silverfish (*Pleuragramma antarcticum*) has been a major component of penguin diet there for at least the past millennium \[[@RSOS172032C20]\]. Given the high marine productivity and krill availability in the northern Ross Sea today, which factors caused a decline in penguins at Cape Adare after the 'supercolony' reached its maximum extent by approximately 1200 BP? We have no explanation for this decline except that it was probably associated with changes in wind patterns, air temperatures, and the size of the Ross Sea polynya that ultimately affected marine productivity \[[@RSOS172032C21]\]. Alterations of this nature have caused total breeding failure, lowered chick production and high mortality events in Adélie penguins in the Ross Sea and East Antarctica \[[@RSOS172032C22],[@RSOS172032C23]\] and continuing impacts over geological time could result in colony decline or abandonment. The relatively brief occupation indicated by the shallow ornithogenic soils that characterizes S4--S5 on the upper terrace supports this conclusion. Ridley Beach remains fully occupied at Cape Adare today, but the beach remains

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paused pointing at the quaint green stone. "What call you that, musician?" The _rebeck_ player paused also, keeping his eyes downward submissively. "They call it smagdarite, Excellence. It comes from Sinde." "Sinned or no sin," echoed Birbal gaily, "the devil is in it. But 'tis a good name. Pass on Smagdarite! Stay"--here the old man half-hidden by his drum essayed to follow--"whom have we here? Old Deena the drum-banger! In what vile stew of Satanstown didst spend the night, villain?" Thus apostrophised, Deena's comically wicked, leering, old face hid itself completely in a salaam behind the drum, and came up again puckered with pure mischief. "That is a question for the virtuous Lord Chamberlain, Mirza Ibrahim," he replied, demurely. The sally was greeted with a boisterous laugh, and Mirza Ibrahim--whose fine clothes dispersed a perfect atmosphere of musk--scowled fiercely. For Satanstown, as ultimate exile of all the bad characters of the city was in his charge, and report had it that he pursued his duty of inspection with more than usual assiduity. "Sit thou here then, by Smagdarite," continued Birbal, recovering from his laugh, "and drum from a distance, lest thou be utterly damned for deserting honourable company. Hark! she begins!" Atma had by this time sunk to the ground beside the King. Her flimsy scarlet skirts curved about her like overblown poppy petals. Her dark eyes, full of fire, were fixed on the unconscious figure so close beside her, and, under the slow circling of her lissome forefinger the little drum held in her left hand was beginning to give out an indescribably mysterious sound like the first faint sobbing of air before an organ pipe breaks into a note. From the distance, almost unheard, came the muffled throbbing of old Deena's drum, and the thin thread of the _rebeck_, light yet insistent like a summer gnat; both kept to the same stern delicacy of rhythm. The singer's voice, high and clear, rose on it almost aggressively-- Hark! and hist! To the list Of the kings who have died In their pride, To the wide, wide, world. MIRUN-KHAN! Lo! He dreamt he was King! But he died In his pride To the wide, wide, world. SO HIS SON SULIMAN Dreamt the dreamings of kings Till he died In his pride To the wide, wide, world. SO THE DREAM WAS JEHAN'S! And he dreamt he was king Till he died In his pride To the wide, wide, world. The rhythmic background broke with the singing voice into troubled triplets, and the King's slack hands gripped in on themselves. Was he listening? Now the tale of the Kings who have died In their pride Is many, and many beside. But the dream is the same, So it came---- The pliant forefinger's whirling gave out a continuous boom like distant thunder amongst hills. Deena's drum throbbed a _reveille_, the _rebeck_ thrilled like a cicala-- TO KUMAN And he dreamt he was King In the wide, wide, world---- "Enough!" The word came swiftly as Akbar turned with a frown. "The end, woman? The end?" There was a pause; then from the very dust of his feet rose her reply: "There is none to the dreaming of kings!" "There is none--to the dreaming--of kings," he echoed slowly, and his eyes scanned her face curiously as he raised her from the ground. "Who art thou, woman?" he asked suddenly; then as suddenly dropped the hands he held, and said coldly: "Give her gold for her song." But once more a fresh feeling came to make him add: "Nay! not gold--let her choose her own reward--what wouldst thou, sister?" His face, grown soft as a woman's, looked sympathetically into hers; she stood before him abashed by the quick tie that seemed to have sprung up between them, unable to realise the chance that was hers. "Quick step!" cried Man Singh brutally. "See you not the Most-Gracious waits? What shall it be? Gold, fal-lals, dresses--the things for which women sell their souls?" She turned on him like a queen. "The women who nurture such heroes as Rajah Man Singh mayhap so sell them; but I----" here her recognition of opportunity swept trivialities before it, she drew herself up to her full height and faced both King and court, her voice ringing like a clarion. "I claim my father's office!" she cried. "Listen, O King-of-Kings! He gave you faithful service when you came to take the crown of India. What to him was Hindu or Mahommedan? He was the King's herald! Akbar was the King! His eldest son--my brother--died to save the honour of the Rajput chief he served before you came! And little Heera--son of his old age, begot _for you_, died ere his baby tongue had ceased to trip in challenging the world--_for you!_ Lo! I have kissed the words to steadiness upon his childish lips when father grew impatient! Why was I not the son? Hid in this dustlike body lies the spirit of my race. Is it my fault that in the dark months of my mother's womb, Fate made me woman, as she made you man? Give me my father's office, O my King, and if my tongue forgets one word of all my father's lore, or if I fail in guarding the King's honour, treat me as woman then--but not till then." The dying fall of her words left the court amazed, almost affronted. Here was a claim indeed! A claim foreign to the whole conservative fabric of Eastern society--which heaven knows had already suffered shock enough at the King's reforming hands! But Akbar took no heed of the looks around him; he was deep in that problem of Sex which was one of the many to claim his quick interest at all times. "The spirit of thy race is in thee, sure enough, O sister," he said slowly. "Manhood is in the woman, as womanhood is in the man--do I not know the latter to my cost? So take thy gift. Thou art the King's Charan from this day. But hearken! If thou failest in thy task, I treat thee not as woman--but as man." He turned away, dismissing her with an autocratic wave from sight, even from thought. "Ushers!" he went on, raising his voice in command, "Sound the advance! I go. And my Lord Chamberlain, bid the travelling Englishmen attend me in the Diwani-Khas. Abul! your arm; I would speak with you about this queen--this woman who has stretched her hand out over the seas to meet mine." He gave a quick joyous laugh and stretched out his own--the true Eastern hand, small, fine, but with a grip as of wrought iron in its slender, flexible fingers. "By God and his prophets I seem to feel it here--a woman's hand close clasped to mine." A fanfaronade of trumpets, shawms, and drums drowned his words, as with a waving of plumes, a blinding glitter of gold and jewels, the royal cortege of Akbar the Magnificent swept on its way. "One moment!" cried Birbal to Man Singh who awaited him impatiently, "I must find Smagdarite first." But both the _rebeck_ player and Atma Devi had gone. Only old Deena remained drumming softly; a fitting accompaniment to the murmurs which rose around him, as the immediate _entourage_ of the King disappeared. "Yet one more insult to Islam," muttered the Makhdum-ul'-mulk spitting fiercely ere he spoke. "And to honest men!" asserted a jealous old Turk who was suspicioned of having drowned more than one young wife on the sly, "for what is woman but ultimate deceit and guile?" "What?" echoed one whose calling could best be described as court-pand

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to buy. He also sells throwing axes, which can be upgraded into a great melee weapon. Increased the soul crafting cost of the extremely overpowered Celestriad. Craft this if you're ready to end the game in a very silly way. Increased the mana used by Starfall to 800. Map The Story of Red Cloud: Fixed a path that leads out of the new Meteorite Dungeon Slogra arena. It wasn't possible to go past before without the Shiny Red Balloon you get from the secret Earth temple. Now you can go this route with only the double jump ability. I also made the Skeletron arena a little less crazy with the skeleton summon statues. I improved the loot of a locked chest in the corruption temple and a couple other chests. Plus some other small things. 1.1o Mod The Tinkerer's Workshop is now sold by the Archeologist as well as the Goblin Tinkerer. Increased the health and damage of the Shadow Dragon. Attraidies' final form also spawns the Shadow Dragon at various times. 3 vanilla enemy lasers have received a damage buff, which has increased the difficulty of the Wall of Flesh, The Twins, the Destroyer, and Skeletron Prime. Mushrooms, Glowing Mushrooms and Goldfish no longer trigger potion sickness when used. (No more accidently eating one of these and dying because you meant to use a healing potion but one of these slipped into your inventory. :) To compensate, mushrooms and glowing mushrooms heal slightly less. Bloodred Moss Clump now heals 25 HP. Increased the difficulty of the Slogra and Gaibon boss fight. Increased spawn chance of Tetsujin in the SHM meteorite biome and from 7-9/10ths width of the map in the sky (more at night, more during blood moons). Map=== The Story of Red Cloud: Added a lot more housing under the village. Added the Tinkerer's Workshop to the village and in a couple other places. Added a couple more small shortcuts in the beginning area. Added a couple more torches to illuminate things you might not normally see depending on your lighting settings. Added a clue-sign in the Merchant's house. Finally decided to add a demon altar below the village. 1.1n Mod=== Increased the length of time between teleporting for all mage-type enemies (a highly requested feature). MP: Some mage enemies will no longer teleport to other players if they are far enough away. Rebalanced Molten Armor set upgrades (melee and magic specialization). They are both now roughly equal but different, and more powerful. Both cost 9000 souls. Added Ancient Dwarven Armor with an upgrade path both from Omnir's Mod. It's a custom melee set that you get from upgrading silver armor, +3 gold bars and 1500 souls. Nerfed Old Double Axe swing speed. Added Shadow Ninja set, a HM end-game tier set that is an upgrade of the Black Belt Gi set (needs 3 soul of fright and 40k souls). It also has a SHM upgrade. Fixed Longinus and it's upgrade not doing double damage when falling. Though I reduced it to 1.5x damage in this update. Removed toolTip that says it randomly heals for now. Removed 3 second "Curse" (can't use items) from Anti-Gravity Blast attack used by Attraidies and others. Increased difficulty of Attraidies. Slight nerf to Star Fall. Slightly buffed Ancient Dragon Lance. Maps=== Added IcyPRO's Minilands v4 - Iced! to the Sandbox Edition Maps folder. This is IcyPRO's updated minilands map, which has many new enhancements. With only 2 demon altars and everything taking place on mini-islands, this should prove to be quite a unique challenge. :) Leave your impressions, comments and more here: http://www.terrariaonline.com/threads/minilands-v4-iced.76761/ Goes without saying, a let's play of this map with the dark souls mod would be super cool to see. Story of Red Cloud: Added gold bars to the first dungeon to craft the upgraded silver armor. Added 2 signs. Added a torch to make gold armor easier to find. Added small short-cut near town well. 1.1m Mod Reduced soul cost of Slime Talisman from 1000 souls to 200 souls. Ancient Great Bow now auto-fires. MP: Fixed spawning of Hellkite Dragon, Seath the Scaleless and the Jungle Wyvern using their respective summoning item. Raised mana cost of Ice Tome 1 by 2 mana (it was pretty OP and still is awesome now - as good as the Bolt tomes). Increased difficulty slightly of Slogra and Gaibon. Increased difficulty and spawn rate slightly of Basalisk Walkers in the meteor biome at day and at night. MP: Fixed Giga Drill sprite not appearing correctly to other players. Increased soul cost of Forgotten Axe and Forgotten Great Axe. Fixed The Unknowable's tool tip about breathing underwater. Fixed Cruel Arrow error message and increased the arrow's speed and number of unique enemies it does 8x damage against. Map The Story of Red Cloud: Added water walking potions to the Eye boss battle in the secret Earth temple. Removed 30 Gravity Potions from Meteor Temple so players can't cheese the Slogra fight. You can now find jungle armor hidden in the meteor temple. Added a sign near eye battle for clarity. Added flippers to the end of the secret earth temple. Added 30 Regen potions to secret Hermes Boots location. Added more goodies to several other chests near the early game plus some other tweaks. Autosave Players is highly useful for MP to guard against player data loss from unexpected crashes. 1.1i Mod Nerfed damage and knockback of Diamond Pickaxe. You'll get this item when creating a new character with either of the Dark Souls Sandbox Editions loaded. Necromancer Elemental no longer drops Forgotten Ice Bow as I forgot I changed it to a end-game SHM weapon. Thorn Decapitator can now be auto-swung. Nerfed the debuffs of Shadow Orb, used primarily by Attraidies. Curse Buildup and Fracturing Armor only have a 1 in 8 chance and the rest are 1 in 2. Rebalanced Fire Spirit Tomes. They no longer pass through walls and fitting with the fire theme, cannot be shot underwater. They can now do critical hits however and have a high chance to light enemies on fire. Added Anomaly0.01's amazing custom sandbox adventure map "Elfheim: An Exploration Map" to the Sandbox Maps folder. This is a MUST-PLAY with the Dark Souls (Sandbox Edition) mod turned on! It is truly a wonderful map with incredible art direction on-par with the style and quality of The Story of Red Cloud map (if no one minds me saying so). :) The map uses an open, no rules sand-box format and everything in the Dark Souls mod is accessible. Give it a try and share your impressions. A let's play of this map/mod combo would also be excellent. Go here to visit the map's official thread: http://www.terrariaonline.com/threads/elfheim-an-exploration-map.102894/ Removed Map "Valley of Lord Gwyn" because it had become outdated compared to the changes made to Valley of Defilment and the updated version essentially provided a merged experience making this map obsolete. BIG THANKS! To Yorai for the inclusion of his Serverside Saving & Commands (SSS) mod. Check out his other awesome mods via the link above. To Anomaly0.01 for the inclusion of his amazing custom adventure map "Elfheim." 1.1h Mod Fixed Oswald of Carim - You couldn't talk to him before due to lacking the townNPC=True variable. Added Wand of Darkness II and Wand of Fire II. Added upgrade path for Fire Spirit Tome with 4 levels in total. Improved Ice 2 Tome. Increased spawning of infantry level dworcs with a slight spawn boost to voodoomasters and headhunters. Made dworcs unable to drown. Demonite Bars and Shadow Armor are craftable at Demon Altars now. Made Attraidies Relics stackable up to 100. Jungle enemies are now vulnerable to fire. In the Sandbox versions, when creating a new character, you now start out with better starting gear. :) Story of Red Cloud: Added "Travel to the Ends of the World Underground" side-quest. The challenge is to travel from the Western Ocean, enter through the sea floor, and travel all the way to the Underwater Observatory without going above ground.

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2592 ]

Using the Full Counting Statistics we computed the electronic current versus internal and external bias and reproduced electron-phonon-induced features such as oscillations versus the internal bias and signatures of Franck-Condon blockade. We stress that the description of this rich dynamics required only the four states of the double quantum dot to be taken into account dynamically. We have found that the dephasing rate of coherences in the pointer basis behaves in some regimes counter-intuitively as a function of the electron-phonon coupling strength. A simple intuitive explanation for this behaviour is that the Franck-Condon blockade stabilizes coherences, thereby also blocking transport through the DQD circuit. The analysis of the entropy production in the polaron master equation has allowed us to study the performance of the system when viewed as a thermoelectric generator converting a temperature gradient into electric power. We have found that in the strong-coupling regime, the system deviates strongly from tight-coupling between energy and matter current, and consequently, the efficiency for this process was found to be significantly below Carnot efficiency. Finally, we want to mention that our method can be generalized to more complex systems and thus allows applications in a variety of transport setups involving phonons such as molecules. Acknowledgments =============== T. B. and G. S. gratefully acknowledge financial support by the DFG (SFB 910, GRK 1588, SCHA ). M. E. has been supported by the National Research Fund, Luxembourg, in the frame of project . Polaron transformation {#App:PolaronTrafo} ====================== We consider the polaron transformation $$\begin{aligned} U=e^{{d_{\rm L}}^\dagger {d_{\rm L}}\mathcal{B}_{\rm L}+{d_{\rm R}}^\dagger {d_{\rm R}}\mathcal{B}_{\rm R}}\,,\end{aligned}$$ with the fermionic annihilation operators $d_\sigma$ and the bosonic operators $$\begin{aligned} \mathcal{B}_\sigma=\sum_q\left(\frac{h^\ast_{q,\sigma}}{\omega_q}a_q^\dagger-\frac{h_{q,\sigma}}{\omega_q}a_q\right)\end{aligned}$$ with bosonic annihilation operators $a_q$. To calculate the transformation rules, we recall the BCH relation $$\begin{aligned} e^X Y e^{-X}&=&\sum^\infty_{n=0}\frac{1}{n!}{{\left[X,Y\right]}}_n\,,\end{aligned}$$ with the short-hand notation ${{\left[X,Y\right]}}_{n+1}={{\left[X,{{\left[X,Y\right]}}_n\right]}}$ and ${{\left[X,Y\right]}}_0=Y$. We first note that the exponential in the polaron transformation can be written in a separated fashion $$\begin{aligned} U&=&e^{{d_{\rm L}}^\dagger{d_{\rm L}}\mathcal{B}_{\rm L}}e^{{d_{\rm R}}^\dagger{d_{\rm R}}\mathcal{B}_{\rm R}}e^{-{d_{\rm L}}^\dagger{d_{\rm L}}{d_{\rm R}}^\dagger{d_{\rm R}}{{\left[\mathcal{B}_{\rm L},\mathcal{B}_{\rm R}\right]}}/2}{\nonumber\\}&\equiv&U_{\rm L}U_{\rm R}U_{\rm LR}\,,{\nonumber\\}U_{\rm LR}&=&e^{{d_{\rm L}}^\dagger{d_{\rm L}}{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi}\,,{\nonumber\\}{\mathrm{i}}\Phi&\equiv&{{\left[\mathcal{B}_{\rm R},\mathcal{B}_{\rm L}\right]}}/2\,,\end{aligned}$$ where it is easy to show that $\Phi^\ast=\Phi$. Consequently, the adjoint operator is given by $$\begin{aligned} U^\dagger=U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}\,,\end{aligned}$$ and we note that ${{\left[U_{\rm LR},U_{\rm L}\right]}}={{\left[U_{\rm LR},U_{\rm R}\right]}}=0$. Alternatively, we can also split the unitary transformation according to $$\begin{aligned} U=U_{\rm R}U_{\rm L}U^\dagger_{\rm LR}\,,\quad U^\dagger=U_{\rm LR}U_{\rm L}^\dagger U_{\rm R}^\dagger\,,\end{aligned}$$ where again ${{\left[U_{\rm LR},U_{\rm L}^\dagger\right]}}={{\left[U_{\rm LR},U_{\rm R}^\dagger\right]}}=0$ holds. Left Mode Operators ------------------- We consider the action of the Polaron transformation on the left fermionic annihilation operator $$\begin{aligned} U{d_{\rm L}}U^\dagger&=&U_{\rm L}U_{\rm R}U_{\rm LR}{d_{\rm L}}U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}=U_{\rm L}U_{\rm LR}{d_{\rm L}}U^\dagger_{\rm LR}U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}{d_{\rm L}}e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} U^\dagger_{\rm L}=U_{\rm L}{d_{\rm L}}U^\dagger_{\rm L} e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi}{\nonumber\\}&=&{d_{\rm L}}e^{-\mathcal{B}_{\rm L}}e^{-{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ The left fermionic creation operator then transforms according to $$\begin{aligned} U{d_{\rm L}}^\dagger U^\dagger={d_{\rm L}}^\dagger e^{+\mathcal{B}_{\rm L}}e^{+{d_{\rm R}}^\dagger{d_{\rm R}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ Right Mode Operators -------------------- In a similar fashion, we evaluate the transformation of the right fermionic annihilation operator $$\begin{aligned} U{d_{\rm R}}U^\dagger&=&U_{\rm R}U_{\rm L}U_{\rm LR}^\dagger {d_{\rm R}}U_{\rm LR}U^\dagger_{\rm L}U^\dagger_{\rm R}=U_{\rm R}U_{\rm LR}^\dagger{d_{\rm R}}U_{\rm LR}U^\dagger_{\rm R}{\nonumber\\}&=&U_{\rm R}{d_{\rm R}}e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} U^\dagger_{\rm R}=U_{\rm R}{d_{\rm R}}U^\dagger_{\rm R} e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi}{\nonumber\\}&=&{d_{\rm R}}e^{-\mathcal{B}_{\rm R}}e^{+{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} \,,\end{aligned}$$ and the adjoint operator becomes $$\begin{aligned} U{d_{\rm R}}^\dagger U^\dagger={d_{\rm R}}^\dagger e^{+\mathcal{B}_{\rm R}}e^{-{d_{\rm L}}^\dagger{d_{\rm L}}{\mathrm{i}}\Phi} \,.\end{aligned}$$ Bosonic Operators ----------------- For the bosonic annihilation operator we obtain $$\begin{aligned} U a_q U^\dagger&=&U_{\rm L}U_{\rm R}U_{\rm LR}a_q U^\dagger_{\rm LR}U^\dagger_{\rm R}U^\dagger_{\rm L}=U_{\rm L}U_{\rm R}{d_{\rm L}}U^\dagger_{\rm R}U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}\left[a_q-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\right] U^\dagger_{\rm L}{\nonumber\\}&=&U_{\rm L}a_q U^\dagger_{\rm L}-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}{\nonumber\\}&=&a_q -\frac{h^\ast_{q,\rm L}}{\omega_q}{d_{\rm L}}^\dagger{d_{\rm L}}-\frac{h^\ast_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\end{aligned}$$ and similarly for the creation operator $$\begin{aligned} U a_q^\dagger U^\dagger=a_q^\dagger -\frac{h_{q,\rm L}}{\omega_q}{d_{\rm L}}^\dagger{d_{\rm L}}-\frac{h_{q,\rm R}}{\omega_q}{d_{\rm R}}^\dagger{d_{\rm R}}\,.\end{aligned}$$ Polaron transformation of the DQD Hamiltonian --------------------------------------------- The total Hamiltonian of the DQD is given by $$\begin{aligned} \mathcal{H} &=& \sum_{k\sigma} \upvarepsilon_{k\sigma} c_{k\sigma}^\dagger c_{k\sigma

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chief who would unite them as Qusayy had united Quraysh, and that there was no other solution to their problem. One of the leading men of the oasis, Abd Allah ibn Ubayy, was favoured by many as a possible king. He had not fought against Aws in the recent conflict but had withdrawn his men on the eve of the battle. He was none the less of Khazraj; and it was exceedingly doubtful whether Aws would be capable of accepting a king who was not of their tribe. The six men of Khazraj delivered the message of Islam to as many of their people as would listen to them; and the next summer, that is, in ad 621, five of them repeated their Pilgrimage, bringing with them seven others, two of whom were of Aws. At'Aqabah, these twelve men pledged themselves to the Prophet, and this pledge is known as the First Aqabah. In the words of one of them: "We pledged our allegiance to the Messenger of God on the night of the First Aqabah, that we would associate nothing with God, that we would neither steal, not commit fornication, nor slay our offspring nor utter slanders; and that we would not disobey him in that which was right. And he said to us: 'If ye fulfil this pledge, then Paradise is yours; and if ye commit one of these sins and then receive punishment for it in this world, that shall serve as expiation. And if ye conceal it until the Day of the Resurrection, then it is for God to punish or forgive, even as He will.' When they left for Yathrib the Prophet sent with them Musab of Abd ad-Dar who had by that time returned from Abyssinia. He was to recite the Koran to them and give them religious instruction. He lodged with As'ad ibn Zurarah, one of the six who had entered Islam the previous year. Mus'ab had also to lead the prayer because, despite their Islam, neither Aws nor Khazraj could yet endure to give one another that precedence. In reference to the practice which had developed in Arabia among the indigent Bedouin, especially in time of famine, of burying unwanted female infants. The rivalry between the descendants of the two sons of Qaylah was of long standing. There had been none the less frequent intermarriages between the two tribes, and as a result of one of these, Asad, the Khazrajite host of Mus'ab, was the first cousin of Sa'd ibn Mu'adh, chief of one of the clans of Aws. Sad strongly disapproved of the new religion. He was therefore angry, yet at the same time embarrassed, to see his cousin Asad together with Musab and some newly converted Muslims sitting one day in a garden in the midst of his people's territory, in earnest conversation with members of his clan. Determined to put an end to such activities, yet not wishing to be involved in any unpleasantness himself, he went to Usayd who was next in authority to himself, and said: "Go thou to these two men who have come to our quarters to make fools of our weaker brethren" - he was no doubt thinking of his younger brother, the now dead lyas, who had been the first man of Yathrib to enter Islam - "and drive them out; and forbid them to come to our quarters again. If Asad were not my kinsman I would save thee this trouble but he is my mother's sister's son, and I can do nothing against him." Usayd took his lance and went and stood over them and said, with as fierce an expression as he could muster: "What bringeth the two of you here, to make fools of our weaker brethren? Leave us, if ye have any care for your lives." Musab looked at him and said gently: "Why not be seated and hear what I have to say? Then, if it please thee, accept it; and if not, keep thyself clear of it." "That is fairly spoken," said Usayd, who liked both the appearance and the manner of the Prophet's envoy; and striking his lance in the ground he sat down beside them. Musab spoke to him about Islam and recited the Koran to him; and Usayd's expression changed, so that those who were present could see Islam in his face from the light that shone in it and the repose that softened it even before he spoke, "How excellent are these words and how beautiful!" he said, when Musab had finished. "What do ye do, if ye wish to enter this rehgion?" They told him that he must wash himself from head to foot in order to be purified, and that he must also purify his garments and then perform the prayer. There was a well in the garden where they were sitting, so he washed himself and purified his garments and testified There is no god but God and Muhammad is the Messenger of God. They showed him how to pray, and he prayed. Then he said: "There is a man behind me who, if he follow you, will be followed without fail by every man of his people, and I will send him to you now." So he went back to his clansmen, and even before he reached them they could see that he was a changed man. "What hast thou done?" said Sa'd. "I spake unto the two men," said Usayd, "and by God I saw no harm in them. But I forbade them to continue and they said: We will do as thou wilt.' "I see thou hast been of no avail," said Sad, taking the lance from his hand and setting off to where the believers were still sitting peacefully in the garden. He remonstrated with his cousin As'ad and upraided him for taking advantage of their kinship. But Musab intervened, speaking to him just as he had spoken to Usayd, whereupon Sa'd agreed to listen to him, and the result Was finally the same. When Sa'd had performed the prayer, he rejoined Usayd and those that were with him and together they went to the assembly of their people. Sa'd addressed them and said: "What know ye of my standing amongst you?" "Thou art our liege lord," they answered, "and the best of us in judgement, and the most auspicious in leadership." "Then I tell you," he said, "I swear I will speak neither to your men nor to your women until ye believe in God and His Messenger." And by nightfall there was no man or woman of his clan who had not entered Islam. Musab stayed with Asad for about eleven months, and many were the people who embraced Islam during that time. Then, when the month of the next Pilgrimage drew near, he returned to Mecca to give tidings to the Prophet of how he had fared among the various clans of Aws and Khazraj. The Prophet knew that the well watered land between two tracts of black stones which he had seen in a vision was Yathrib, and he knew that this time he too would be of the emigrants. Now there were few people in Mecca whom he trusted so much as his aunt by marriage, Umm al-Fadl. He was also certain that his uncle Abbas, although he had not entered Islam, would never betray him and never divulge a secret confided to him. So he told them both that he hoped to go and live in Yathrib and that much depended on the delegation which was expected from the oasis for the coming Pilgrimage. On hearing this, 'Abbas said that he felt it his duty to go with his nephew to meet the delegates and speak with them, and the Prophet agreed. Not long after Musab's departure, some of the Muslims of Yathrib set out upon the Pilgrimage as had been arranged between him and them, in all seventy-three men and two women, hoping to make contact with the Prophet. One of their leaders was a Khazrayite chief named Bara', and during the first days of the journey a preoccupying thought came over him. They were on their way towards Mecca wherein was the House of God, the Kabah, the greatest centre of pilgrimage for the whole of Arabia; and therein was also the Prophet, to whom they were going, and it was there that the Koran had been revealed, and thither their souls were moving ahead of them in aspiration. Was it then right or reasonable, when the time came for prayer, that they should turn their backs on that direction and face towards the north, towards Syria? This may have been more than a mere thought, for Bara' had only a few more months to live, and men who are near to death are sometimes gifted with premonitions. However that may be, he told his companions what was in his mind, whereupon they said that as far as they knew the Prophet was wont to pray towards Syria, that is towards Jerusalem, and they did not wish to differ from him. "I shall pray towards the Kabah," said Bara', and he did so throughout the journey, while all the others continued to pray towards Jerusalem. They remonstrated with him to no avail, except diat when they arrived in Mecca he had some misgivings and he said to Kab ibn Malik, one of his younger clansmen - and one of the more gifted poets of Yathrib: "Son of my brother, let us go to the Messenger of God and ask him about what I did on this journey

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.wikipedia.org/wiki/Chatzilla <Gnea> LieZ^: why do you need it? <LieZ^> deluge torrent client :D <enmasse> teq can i copy and paste what you told me to do sudo apt-get install irssi <Gnea> !language | teq <ubottu> teq: Please watch your language and topic to help keep this channel family friendly. <ubunubi> LieZ^: both dbus-x11 and dbus are both in the repo <hiptobecubic> i have ssh'd to another box using the -X flag to enable X11, but how can i start apps and have them show up on the remote display instead of my local display <ubunubi> LieZ^: and installed by default on my system anyway <LieZ^> are they? hold on a sec <teq> enmasse: yes <ra21vi> unop: filename is ${USER}.foo.bar would always be root.foo.bar when executed with sudo <herrmess> enmasse: System->Administration->Synaptic Package Manager-> Search for Privoxy <Shujah> enmasse, tor & privoxy are on ubuntu repos so should work without any tweaking? have you tried installing them <ubunubi> LieZ^: version 1.1.20-1ubuntu2 (for both) <herrmess> Both Privoxy and Tor are there, mark them for install. <enmasse> shuraj im confused on HOW TO install them <enmasse> okay will do herrmess, what i tried was going to the main site for tor and getting it from there <enmasse> what does this mean sudo apt-get install irssi? <teq> hey guys I think i fcked my repository how can i get it back? thanks <ubunubi> teq: we need more details than that <trashguy> enmasse, it istall the irc client irrsi <LieZ^> im getting package-dbus-x11 has no installation candidate? <enmasse> trashguy, i've installed the client where do i find it though? <Shujah> open gnome menu > system > administration > synaptic manager (search for tor) select press apply and so on <teq> ubunubi: packages that should be in the repo are not there <trashguy> enmasse, type irssi <unop> ra21vi, you shouln't call the same script itself, you need to call another script passing the filename as an argument - sorry if that name "myscript" mislead you <ubunubi> LieZ^: are you on an up-to-date hardy intsall? <teq> ubunubi: how can i reconfigure it? <rgb> crimsun: Copy? <LieZ^> ubuntu server my good man <izmeh> man, i'm loving linux <hlfshell> hey guys - trying to advise a friend with clonezilla. anyone know of a repository that has the package for it or am i going to have to walk him through installing it? <zyrorl_> izmeh - id love it more if i could somehow unlock draft-n wireless on it:S <ubunubi> LieZ^: dunno what to tell ya. both of them are showing installed, and in the repo and up to date for me, and i only have the default repo's turned on <perhamlinux> Gnea, are you there? <izmeh> zyrorl_: wish i could help ya <ubunubi> LieZ^: search for x11 and dbus with a space between them, and Name and Description turned on <ubunubi> LieZ^: in synaptic <solexious> [Q] Is there a ubuntu command line program to see the status of a jetdirect printer? <bayden> can movies run on ubuntu <LieZ^> soound like a noob mode, how do i get on synaptic im only used to working with CLI <ubunubi> bayden: sure if you install the correct codecs from mediabuntu <Shaba1> what type of movies bayden <ali__> hey guys <Shaba1> In other words what video formats are you talking about <ubunubi> LieZ^: do you have an X desktop environment setup? <ali__> its me enmasse on irssi <ali__> :D <bayden> well the dark knight <LieZ^> yes im on vnc and ssh now two connections <enmasse> hey im ali on irssi <bayden> a 2 or 3 hour movie <zyrorl_> bayden: if you mean porn yes. <ubunubi> LieZ^: just gksudo synaptic then <Shujah> enmasse had such a french seductive touch to it :( <zyrorl_> if you mean anything else, no it wont work <enmasse> lol <bayden> ooo where can i find tHAT <bayden> =) <bayden> LOL <zyrorl> just do an apt-get install vlc <zyrorl> it'll play anything <bayden> mediabuntu? <lenswipe> terminal keeps crashing when i start it, anyone got ny ideas?? <zyrorl> or mplayer but you'll probably want mplayer-gui as well <lenswipe> ï»¿terminal keeps crashing when i start it, anyone got ny ideas?? <monostone> I love xine <bayden> do i just download it then install it? <lenswipe> ï»¿terminal keeps crashing when i start it, anyone got ny ideas?? <rgb> zyrorl: It's also horrible with subtitle tracks. <zyrorl> or xine <monostone> it plays dvd isos, everything <ubunubi> !patience | lens <ubottu> lens: The people here are volunteers, your attitude should reflect that. Answers are not always available. See http://wiki.ubuntu.com/IrcGuidelines <Shujah> lenswipe, have you edited the terminal profiles <zyrorl> rgb - i speak english... natively so i dont need subs <zyrorl> usually <lenswipe> Shujah: not that i know of... <teq> lenswipe: try sudo aptitude upgrade && update <zyrorl> but yeah vlc's subtitles rendering is horrible <overlordpuppy> Is there a mlt and mlt++ package? <lenswipe> teq: i cant, terminal keeps crashing... <acid2_> Shujah: that doesn't fix the fact that characters overlap with some fonts <ubunubi> lenswipe: you'll probably have to reboot into recovery mode <teq> ctrl+alt+f1 and then do that <rgb> zyrorl: Many English speakers require subtitles to watch certain content. Not every English Speaker watches only video in the English language. <Shaba1> I use vlc <lenswipe> ubunbi: and do what? <Shaba1> though I need to find another dvd burning program for windows <rgb> In my case, yeah I need my subtitles. <Shaba1> I have an old copy of nero vision experss that has seen its best days <lenswipe> ubuntubi: what do i do when im in recovery mode? <zyrorl> rgb: i can also speak portuguese natively, and am fluent in spanish and can understand french and german <LieZ^> ubunubi: must be something wrong with my repos its not showing <zyrorl> :P <zyrorl> i agree though... vlcs subs are pretty poor <rgb> zyrorl: Similar here, English, Dutch, German and French. <ubunubi> lenswipe: i'd assume delete your bash profile <rgb> zyrorl: Speak the first two, understand the latter. <zyrorl> i'm assuming you watch many asian movies? <rgb> zyrorl: Yup. <lenswipe> ubuntubi: and how do i do that? <zyrorl> fair enough <ubunubi> lenswipe:: try alt+f2, sudo gnome-terminal and see if it launches. if it does, it's just a matter of removing your user profile <aesonn> hello, anyone here have any experience using oracle 10g express on ubuntu? <lenswipe> ubuntubi: kk <Shujah> who was asking about the subs ? <rgb> zyrorl: Chinese and Japanese are a bit too hard to learn quickly at sufficient level. <ubunubi> lenswipe:: er gksudo gnome-terminal, sorry <

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traction. The sham traction was given with a specially developed brace that tightens in the back during traction. To the patient, the experience is that of traction. The patients and outcome assessor were blinded for the assigned treatment. 151 patients with at least six weeks of non-specific low back pain were randomised. Intention to treat analysis showed no differences between the groups on all outcome measures (patients' global perceived effect, severity of main complaints, functional status and pain); all 95% confidence intervals included the value zero. The number of withdrawals from treatment, loss to follow-up, and protocol deviations was low. Consequently, the per-protocol analysis showed results similar to the intention to treat analysis. Subgroup analyses did not show any group for which traction might seem promising. Our data do not support the claim that traction is effective for patients with low back pain.Order Michigan Supreme Court Lansing, Michigan March 30, 2018 Stephen J. Markman, Chief Justice Brian K. Zahra Bridget M. McCormack 157340-2(97) David F. Viviano Richard H. Bernstein Kurtis T. Wilder Elizabeth T. Clement, MELISSA MAYS, MICHAEL ADAM MAYS, Justices JACQUELINE PEMBERTON, KEITH JOHN PEMBERTON, ELNORA CARTHAN, RHONDA KELSO, and ALL OTHERS SIMILARLY SITUATED Plaintiffs-Appellees, SC: 157340-2 v COA: 335555, 335725, 335726 Ct of Claims: 16-000017-MM GOVERNOR OF MICHIGAN, STATE OF MICHIGAN, DEPARTMENT OF ENVIRONMENTAL QUALITY, and DEPARTMENT OF HEALTH AND HUMAN SERVICES, Defendants-Appellees, and DARNELL EARLEY and JERRY AMBROSE, Defendants-Appellants, and CITY OF FLINT, Not Participating. _________________________________________/ On order of the Chief Justice, the motion of plaintiffs-appellees to extend the time for filing their answer to the application for leave to appeal is GRANTED. The answer will be accepted for filing if submitted on or before May 3, 2018. I, Larry S. Royster, Clerk of the Michigan Supreme Court, certify that the foregoing is a true and complete copy of the order entered at the direction of the Court. March 30, 2018 Clerk import React, { useCallback, useContext, useState } from "react"; import { UploadyContext, useBatchAbortListener, useBatchStartListener } from "@rpldy/shared-ui"; const StoryAbortButton = () => { const context = useContext(UploadyContext); const [uploadingId, setUploading] = useState(null); useBatchStartListener((batch) => { setUploading(batch.id); }); useBatchAbortListener((batch) => { console.log(">>>>> StoryAbortButton - (hook) BATCH ABORT - ", batch); }); const onClick = useCallback(() => { context.abortBatch(uploadingId); }, [context, uploadingId]); return context && uploadingId ? <button onClick={onClick} data-test="story-abort-button">Abort</button> : null; }; export default StoryAbortButton; Tag: role People have different views about the role and function of museums. In my opinion, museums can and should be both entertaining and educational. On the one hand, it can be argued that the main role of a museum is to entertain. Museums are tourist attractions, and their aim is to exhibit a collection of interesting […] Every person holds a very important place in a society and their actions towards the laws and norms effect the whole system in numerous ways.Its vital to play a positive role in order to create a constructive environment for individuals.As much as optimistic and genuine opinions have a great impact in boosting confidence towards each […] In these days, numbers and statistics have bigger voice than insubstantial aspects of our life. It is under this circumstance where the numerable academic achievement of each school has been stressed. At one extreme, some people argue that the role of school teacher is to just impart textbook knowledge to his/her pupils. However, this impoverished […] There is no shortage of debate about whether today’s extended family still play a pivotal role or not. In my opinion, that the role of relatives was not crucial than it once was. I feel this way for two main reasons, which I will explore in the following essay. First of all, certain roles once […] People in our time have more opportunities to succeed but they also have to face more fatal competition. Success in every aspect of the society requires extraordinary efforts in addition to some luck and various kinds of social network since we are living in an age which emphasizes team work and cooperation between each other. […] The statement is flawed due to its downplaying the role of school or college in cultivating students, as far as I am concerned. It’s reasonable to associate personal discipline with great significance concerning learning knowledge, but there are still considerable students lacking motivation in need of timely and appropriate guidance from their teachers as well […] There is no shortage of debates about whether we should play a role as a leader or an individual player, and each view has its own strengths and weaknesses. Personally, I am of the opinion that people should lead a team rather than follow other members. I feel this way for two main reasons, which […] It is common to argue about who should be the best teacher between family or school, indeed, this issue is born consequently at the lost of teachers’ importance. Nowadays parents have a crucial position in education while in the past was ordinary to combine the two figures. There are people against or in favor the […] Nowadays, social networks and television play such an important role in society that they have created certain stereotypes which makes it difficult to determine what is really worth about a person. Therefore, social status is attributed by how many likes people have on their posts on Facebook or how many followers they have on Instagram. […] The statement given by the author itself is a debatable one as it won’t have any definite answer as many people would have different opinions. Parents are the two most important building blocks for every living beings on this planet. A teacher is one who is always looked at for help guidance and also for […]Thursday, June 2, 2016 This book gives you “more” of what you need 4 stars The More of Less: Finding the Life you Want Under Everything You Own by Joshua Becker This month’s review is from my husband, who is striving to be a minimalist in a world full of stuff… In the American culture today, stuff can dictate our lives. We feel we must work hard to keep up with others and their stuff, so we put too much value on possessions over deep relationships. But in this book, author Joshua Becker teaches how one can become a minimalist at heart and find happiness in less. He offers practical baby steps in how to downsize, taking the fear of getting rid of everything all at once. He says 80% of what is in our house we only use 20% of the time. So why do we have all the stuff? This book helps one evaluate what they have and asks hard questions like: What if, instead of being embarrassed over the type of car we drive, we became embarrassed over how often we take the luxury of automobile ownership for granted? What if, instead of being embarrassed because our house seems too small, we became embarrassed over the amount of unused space within it? What if, instead of being embarrassed over the brand of our clothing, we became embarrassed over the enormity of our walk-in closet? Overall, this book helps readers see the world of excess and reminds us as Christian how we are to live differently than the world and find happiness not in stuff, but of the things of God. *I received this book for free from Blogging for Books for this unbiasedDimeric trigger factor stably binds folding-competent intermediates and cooperates with the DnaK-DnaJ-GrpE chaperone system to allow refolding. Trigger factor (TF) is the first chaperone encountered by the nascent chain in bacteria and forms a stoichiometric complex with the ribosome. However, the functional significance of the high cytosolic concentration of uncomplexed TF, the majority of which is dimeric, is unknown. To gain insight into TF function, we investigated the TF concentration dependence of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) reactivation yield in the presence and absence of the DnaK-DnaJ-GrpE chaperone

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Connectivity Map with this signature can be found in the supplementary data, which suggests that rds02 has positive connections to $107$ reference profiles, and negative connections to $119$ profiles. However once again we know these must be all false connections. Conversely, the new method presented in this paper gave results that agree with the underlying truth. With the criteria set above there was 1 connection found significant ($p<1/453=0.0022$). Since we expect on average 1 false connection, this declared significant connection can be taken as false. The two examples of random gene signatures above revealed that on the individual treatment instance level Lamb et al’s Connectivity Map gave many false connections because no safeguard was provided for these. The reason for this was in the way the connectivity scores were calculated. Briefly, Lamb et al’s connectivity score was based on the Kolmogorov-Smirnov statistic. At first two K-S statistics were calculated, one for the up-regulated genes, and one for the down-regulated, then these two values were combined to give a single connectivity score. This way of defining the connection score was unnecessarily complex, which made the calculation of a possible p-value on an individual level difficult, if not impossible. rank Compound ID score pvalue ---------- -------------- ---------- ---------- -------- 1 (-)-catechin 1101 0.334 0.003 2 sirolimus 1022 0.312 0.006 3 phentolamine 1138 0.309 0.007 4 5162773 892 0.292 0.011 5 resveratrol 595 0.286 0.013 $\cdots$ $\cdots$ $\cdots$ $\cdots$ 451 felodipine 848 -0.002 0.988 452 estradiol 988 -0.001 0.991 453 bucladesine 959 0.001 0.993 : \[tab-rds01-sdz\] The connection scores for the random gene signature rds01 using the new methods. To control the expected number of false connections at 1, the threshold p value was set at $1/453=0.0022$. No connection was found to be significant, which agrees with the underlying truth. On the treatment set level, Lamb et al’s Connectivity Map provides a permutation p value when a set of treatment instances associated with the same compound were viewed as a whole. The permutation p value was calculated by comparing a statistic (again based on K-S statistic) of the treatment set with the distribution of many random-set statistics. Those random sets were formed by randomly selecting treatment instances from all instances. From the way the permutation p value was calculated, it was clear that the following null hypothesis was being tested: [*The set of instances in question have the same pattern (distribution) of connections with the query gene signature compared with a randomly formed set of the same size.*]{} A null hypothesis such as this is not the most appropriate one to test, because it is not directly relevant to the question of whether the query gene signature had any real biological connection to the treatment set. Lamb et al themselves also recognized that more rigorous methods for the estimation of statistical significance were probably required[@Lamb-etal-Science-2006]. Putting its appropriateness aside, if we do use the permutation p values from Lamb et al’s Connectivity Map to control false connections, the same criteria for setting threshold p value can be used. The results of significance analysis on the connections between the two random gene signatures and the $164$ treatments sets can be found in the supplementary data. In this instance both connectivity maps gave the right answers for these two random gene signatures. However, for Lamb et al’s Connectivity Map permutation p values were not available for all the $164$ treatment sets. For those treatment sets which only contain $1$ treatment instance or those sets with mean connectivity score $0$, no permutation p values could be calculated, and hence no statistical significance. This problem affects the coverage and consequently the sensitivity of Lamb et al’s Connectivity Map, because real biological connections between a query gene signature and any of those treatment sets may not be recognized. Querying the connectivity maps with experimentally derived real gene signatures ------------------------------------------------------------------------------- ![HDAC inhibitor gene signature: The Venn diagram summarizing the findings of significant connections as identified by the connectivity maps. A represents the instance-level analysis using the new method; B, the set-level analysis using the new method; C, the set-level analysis using Lamb et al’s Connectivity Map. The label “AB 13” means that $13$ compounds are identified as significant solely by A and B (not C), “B 4” means that $4$ compounds are identified as significant solely by B (not A, not C), and so on. The areas are approximately proportional to the numbers they represent.[]{data-label="fig-HDAC"}](HDAC.eps){width="8.5cm"} ### HDAC inhibitors To test the ability of the new method for identifying real biological connections we utilized some of the same examples used in [@Lamb-etal-Science-2006] to compare with Lamb et al’s Connectivity Map. The first example was a gene signature of histone deacetylase (HDAC) inhibitors (Lamb’s gene signature sigs01), which was compiled from [@Glaser-etal-MolCancerTher-2003] on the responses of T24, MDA435 and MDA468 cells respectively to three histone deacetylase (HDAC) inhibitors: vorinostat, MS-27-275, and trichostatin A. This gene signature consisted of 8 up- and 5 down-regulated genes, represented by $25$ Affymetrix probe-set IDs on the Affymetrix HG-U133A microarrays. As Lamb et al’s Connectivity Map does not provide any safeguard on individual treatment instance level against possible false connections, we can only use the results of Lamb et al’s Connectivity Map on the treatment set level. In total 6 compounds (vorinostat, trichostatin A, resveratrol, geldanamycin, valproic acid, and 17AAG) were identified to have significant positive connectivity with the HDAC inhibitor gene signature; and 2 compounds (5182598 and fludrocortisone) had significant negative connectivity. Vorinostat, trichostatin A, and valproic acid are known HDAC inhibitors thus the identification of these can be regarded as a success. However another known HDAC inhibitor HC-toxin, a reference profile of which was contained in the database, was not identified. This happened because there was only one treatment instance of the compound HC-toxin in the database and so no permutation p value could be obtained using Lamb et al’s method. Based on their instance level results, Lamb et al highlighted HC-Toxin in [@Lamb-etal-Science-2006] as it had the 7th highest connectivity score (0.914) of all instances in the dataset. However, as the two examples of random gene signatures showed Lamb et al’s instance level analysis gave false connections even for the highest connectivity scores 1.0. So the rational choice is to disregard the instance level results from Lamb et al’s Connectivity Map. We used this same HDAC inhibitor gene signature to query the new connectivity map presented here, with p values calculated at both the individual instance level and the treatment set level. $56$ treatment instances, representing $22$ distinct compounds, were found to have significant connections to sigs01. On the treatment set level $24$ compounds were found to have significant connections with the signature. Near the top of the significant connection list were those known HDAC inhibitors highlighted in [@Lamb-etal-Science-2006]. Importantly though also included in the output was HC-Toxin, which was not identified by the set-level analysis Lamb et al’s Connectivity Map. The full results of querying both connectivity maps using the HDAC inhibitor gene signature are included in the supplementary data. In Fig. \[fig-HDAC\], we summarize the number of significant connections as identified by: (A) Instance level analysis using the new method presented here; (B) Set level analysis using the new method; (C) Set level analysis using Lamb et al’s Connectivity Map. In total, our method (A) and (B) combined identified 27 compounds and Lamb et al’s Connectivity Map identified 8 compounds, as having significant connections to the HDAC inhibitors. Our method missed only 1 of the 8 compounds found significant by Lamb et al’s Connectivity Map, while the latter missed 20 of the 27 compounds identified by our method, with HC-toxin among the 20 compounds that were missed. The HDAC inhibitors example thus shows that our new method is more sensitive at detecting real connections. With the increased sensitivity and false connections being properly controlled, the potential benefit of our method is obvious. In this example, the set-level analysis of Lamb et al’s Connectivity Map identified 8 compounds with a false discovery rate of $12.5\%$ (1/8), while the set-level analysis using our method identified 24 compounds with a false discovery rate of $4.2\%$ (1/24). Based on the findings of the connectivity maps, researchers can prioritize a small sub set of those compounds for further investigations and/or developing new biological hypotheses. For this example, using Lamb et al’s Connectivity Map, the chance of pursuing a false connection is $12.5\%$, while using our method it is much lower at $4.2\%$. In practice this would save the researchers an enormous amount

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lose. Over all it really doesn't affect my daily life like being blind or deaf would. Silver linings, you know. ;) Well I can answer this because for the last three months I have not been able to smell due to sinitus infection that just wont go away. Although I am not as hungry and do not crave food I stil eat what I fancy and the body recalls the taste and smell of the food. I could be eatting anything! Although I can not taste at all my brain kicks in and tells me what it is supposed to taste like. It is very depressing I can tell you! Although not being able to smell does have its advantages. My husband has done all the cooking because I am a danger in the kitchen. If I place bread under the grill it would catch fire or burn because I simply get distracted and cant smell it. I can not season food or cook from scratch as I have no idea what it tastes like! And best of all if the puppy poops behind the chair I cant smell it, so my husband cleans that up as well. Its that pleasure pain thing! I am hoping for a full recovery soon as eatting is so boring without the smell and tastes of the food I love.Story highlights Sen. Sanders said Monday that health care is a "right, not a privilege" Sanders spoke to the NAACP national convention Washington (CNN) Sen. Bernie Sanders slammed Senate Republicans' health care bill as "destructive" and "irresponsible" in a speech at the NAACP national convention in Baltimore on Monday. Calling the bill the "cruelest, most destructive and irresponsible piece of legislation ever brought to the United States Senate in the modern history of this country," Sanders highlighted the possible effects of the bill's provisions, which include cutting Medicaid, defunding Planned Parenthood and roadblocks for those with pre-existing conditions. Sanders also criticized Republicans for not holding hearings on the bill and writing it "behind closed doors." "This legislation is overwhelmingly opposed by the American people, overwhelming opposed by virtually every health care organization in this country," Sanders said, listing a number of organizations that oppose the bill, including AARP and the American Cancer Society. Sanders' remarks were a part of the conference's policy discussions, which included a panel of Democratic legislators such as Maryland Sen. Ben Cardin, Illinois Sen. Tammy Duckworth, California Sen. Kamala Harris, Virginia Rep. Bobby Scott, and Texas Rep. Sheila Jackson Lee as well as Republican Virginia Rep. Scott Taylor. Read MoreMaduromycosis of the brain. Case report. A rare case of a gas-containing brain abscess due to verified maduromycosis is described. Blackish material over the abscess cavity revealed the fungal elements. The pus from the abscess contained Streptococcus hemolyticus and Klebsiella organisms.This invention is directed at reducing cravings in mammals. More specifically the present invention is directed at reducing the cravings of a mammal to any dopamine mediated cravings including food or addictive substances. Considerable research has been directed at obesity, nicotine addiction and substance abuse. The cost to society is very high from the health costs associated with obesity, tobacco consumption, and drug and alcohol abuse. While many individuals choose to lose weight, stop smoking and/or cease abusing drugs or alcohol, they frequently relapse into their former patterns of behavior during or shortly after they complete their treatment programs. Often this may be caused by subtle signals in the environment which initiate cravings in the individual for food or the substance which they had abused. Accordingly, it would be desirable to provide a substance which would suppress cravings for food and/or abused substances in a predisposed mammal. The use of D.sub.1 antagonists in the treatment of drug abuse is known. U.S. Pat. Nos. 4,973,586 and 5,302,716 disclose the use of D.sub.1 antagonists in treating drug dependence. A dosage range of 0.02-10 mg/kg was suggested, with 2.0 mg/kg divided over 1-3 administrations per day being particularly preferred. Spealman, et al., Neurochem. Int. Vol. 20 Suppl., 99147S-152S (1992) discloses that cocaine is a robust reinforcer and often is used as a standard for evaluating the reinforcing effects of other drugs. When SCH 39166 was administered to monkeys, a 3-fold or greater increase in the dose of cocaine usually was required to restore characteristic self-administration performances. Barrett-Larimore and Spealman in Society for Neuroscience Abstracts 22(2): 92 5 (1996) reported that several compounds including the D.sub.1 antagonist SCH 39166, a D.sub.2 antagonist and a D.sub.3 /D.sub.4 antagonist all were able to attenuate the cocaine-seeking behavior in a cocaine relapse model. Clifton, 1995 and Clifton, 1991 have indicated that the D.sub.1 antagonists SCH39166 and SCH 23390 have no effect on total food intake, meal size or feeding rate up to 3 mg/kg. Caine and Koob in The Journal of Pharmacology and Experimental Therapeutics Vol. 270, No. 1 pp. 209-218 (1994) describe tests on D.sub.1 antagonists SCH 39166 and SCH 23390 for cocaine and food self-reinforcement. D1 antagonists were found to affect cocaine self-administration. Chausmer and Ettenberg in Pharmacology Biochemistry and Behavior Vol. 57, No. 4, pp. 681-685 (1997) conducted tests on D.sub.1 and D2 antagonists in response re-instatement properties of food reward. They found that the D.sub.2 antagonist raclopride was sufficient to block the response-reinstating effects of food reinforcement, but the D.sub.1 antagonist SCH 39166 was not. Nathan, Breskin and Batki in CNS Drugs Jul. 10, 1998 (1) pp. 43-59 summarize results in treating cocaine addiction with various drugs. Lancet, Volume 347 pp. 504-508 (Feb. 14, 1996) reports that haloperidol was tested for decreasing desire for an abused substance. However, this compound is reported to have had significant adverse side effects, such as dysphoria, restlessness or stiffness, which reduces the desire for individuals to take them. It has been difficult to develop substances which inhibit craving in mammals, particularly humans, because of the lack of reliable animal models which correlate well with human behavior. Substances which are administered to reduce craving should not produce significant physiological effects, such as stimulation of mood or elevate blood pressure or heart rate. This could result in the substitution of one abused substance for another. Compounds which dampen the desire for the abused substance also should not exacerbate the physiological symptoms of the abused substance in the event the individual relapses and takes the abused substance. Substances administered to reduce craving also should not produce significant adverse affects, such as dysphoria, restlessness or stiffness. Accordingly, it is desirable to provide a compound and method of treatment which will be active in reducing craving for the abused substance, and which does not exacerbate the sympathetic response rate caused by the abused substance and which has favorable pharmacodynamic effects. It also is desirable to provide a compound and method of treatment which blocks the euphoric and dysphoric effects of the abused substance.Naomi C. Writer and researcher Plymouth, United Kingdom I can offer fantastic rates on a wide variety of article writing assignments, with a fresh and engaging style which is perfect for organisations and businesses that are a little...Read moreI can offer fantastic rates on a wide variety of article writing assignments, with a fresh and engaging style which is perfect for organisations and businesses that are a little different from the mainstream. Discounts are available for charities, so please get in touch to discuss your requirements. I have been working as a freelance writer and researcher since 2010 providing SEO, web content and high quality articles for a wide variety of high profile clients. I also home-educate my two children with the help of my partner and am committed to a lifestyle which has their best interests at heart. The fact that I spend so much time with my kids and engage in many creative and play based activities throughout the day gives my work a focus and insight which is unique yet incredibly accessible. As a supplement to my writing income, I work as a storyteller and independent ambassador for Barefoot Books. Barefoot Books began with two mothers who wanted their children to have books that would feed the imagination, while instilling a respect for diversity and a love of the planet. I am part of a world-wide community of writers, artists, storytellers, musicians, and others who are committed to providing timeless stories and captivating art that can help children become happy, engaged members of a global society. Area Covered: Global Industry: Outsourcing/Offshoring Employees: 1 Work Experience ----------------- Summary: I have been home-shoring for a number of years and have covered a wide variety of different fields including call-center work, customer services and direct sales. Literature is one of my greatest loves, so it was a natural progression for me to become a freelance writer and I have worked with the same company since 2010 as well as taking on various other assignments from other clients. I also home-educate my two children with the help of my partner and am committed to a lifestyle which has their best interests at heart. The fact that I spend so much time with my kids and

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) - Mitsubishi UFJ Financial Group Inc (MUFG) on Wednesday sued New York’s banking regulator to stop its effort to continue to supervise Japan's largest lender after it switched its state branches to federal oversight this week, according to court filings. NEW YORK (Reuters) - Mitsubishi UFJ Financial Group Inc (MUFG) on Wednesday sued New York’s banking regulator to stop its effort to continue to supervise Japan's largest lender after it switched its state branches to federal oversight this week, according to court filings.Q: SQL query different results between workbench and PHP script in the same date range I have a PHP script that helps me to make some financial reports like capital, profits, total sold item, total item in store between 2 dates: $result[] = 0; $res[] = 0; $fetchStat[]=0; if(isset($_POST['generate_capital'])) { $from_d = $_POST['from_d']; $to_d = $_POST['to_d']; $stat = "SELECT sum(sell_quantity*(sell_price-init_price)) AS 'rebeh', sum(init_price*(quantity-sell_quantity)) AS 'capital', sum(sell_price*sell_quantity) AS 'profits', sum(quantity) AS 'total_item', sum(sell_quantity) AS 'total_sell' FROM purchases WHERE date_now BETWEEN :d1 AND :d2"; $stmtStat = $conn->prepare($stat); $stmtStat->bindValue(':d1', $from_d); $stmtStat->bindValue(':d2', $to_d); $execStat = $stmtStat->execute(); $fetchStat= $stmtStat->fetchAll(); } Now, the same query in MySQL workbench will give me a specific result: SELECT sum(sell_quantity*(sell_price-init_price)) AS 'rebeh', sum(init_price*(quantity-sell_quantity)) AS 'capital', sum(sell_price*sell_quantity) AS 'profits', sum(quantity) AS 'total_item', sum(sell_quantity) AS 'total_sell' FROM purchases WHERE date_now BETWEEN '2016-02-02' AND '2016-05-09' The result is: And the same query in the PHP script with the same date range will give me other values: I've changed the Arabic keywords with English ones so you can see the difference. Any help is appreciated. EDIT: Adding var_dump result for 2 dates A: As it stands, it appears that the most likely cause is that your date formats have the month and day in the wrong order, for the 2nd of February, that doesn't matter, but for the 9th of May, it would become the 5th of September. Now, the reason that the data for the 9th of May isn't included when you run the query directly is because a date is actually midnight on that date, making it exclusive of that date when it comes at the end of a between. It's possible there is something else, so if this doesn't work, try echoing out all your values at every point, until you know exactly what is being run, and it should become clear. To clarify, when using '/' in a date, MySQL uses the following format: '%d/%m/%Y' Which would explain why it works if you enter a string into your text box. Information Land of Common Sense (2017) Summary Sang Shik is described as a “wacko secretary” who dreams of being a top diplomat: Good-looking, athletic, and a competent fighter, he is described as “halfway between Jang Geu Rae [of Misaeng] and [spy comedy] Kingsman.” Nara, meanwhile, is a diplomat with strict principles who never does things by half-measures and doesn’t know how to hide even the smallest emotion, who’s described as halfway between the perfect diplomat and a nutjob--- Name: mirtop URL: https://github.com/miRTop/mirtop Description: Command line tool to annotate miRNAs with a standard mirna/isomir naming --- This tool is dedicated to the creation and management of miRNA alignment output using the standardized GFF3 format (https://github.com/miRTop/mirGFF3). A unified miRNA alignment format allows to easily compare the output of different alignement tools. Currently, mirtop can convert into mirGFF3 the outputs of commonly used pipelines, such as seqbuster, isomiR-SEA, sRNAbench, Prost! as well as BAM files. Best Most Stylish Reclining Couches 2017 By adminPosted on August 16, 2017November 11, 2017Best Most Stylish Reclining Couches 2017 February 2018 Reclining Couches – This The Most Stylish Reclining Couches 2017 photos was upload on August, 16 2017 by admin. Here latest Reclining Couches photos collection. Download other ideas about Reclining Couches in our other blog. Click on wallpapers to get The Most Stylish Reclining Couches 2017 in high resolution.Power Math for Power Circuits How Maple’s 3D capabilities helped solve the mystery of gate resistance on shoot through Desktop Engineering, October 2006 Alan Elbanhawy, a director at Fairchild Semiconductor International, examined the effects of lumped and distributed gate resistance on the phenomenon of shoot through (also known as cross conduction) in synchronous buck. He concludes: “Using Maple allowed us to investigate the interaction of all the important parameters in 3D representations that helped us understand the extent of the interdependencies. The 3D capability offers a very powerful visualization tool of the complete results. To achieve the same results using any other numerical simulation environment requires enormous amount of batch simulation, data compiling, and graphing.”Recurrent bacterial meningitis and impaired host defences. Recurrent pyogenic meningitis is uncommon. Its aetiology is often associated with impaired host defence mechanisms. Two such examples are discussed. Case 1 resulted from an anatomical defect and Case 2 a defect of the complement system.Q: Displaying Contents of an ArrayList that contains objects of another class with private fields How do I print the album title from the array-list if the contents of the object is in a private field in another class? Display Method public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { System.out.println(AlbumList.get(i)); } } Album Class that has private variables title and price. class Album { private String title; private double price; Album(String title, double price) { this.title = title; this.price = price; } public String getTitle() { return this.title; } public double getPrice() { return this.price; } } Cart Class adds songs to arraylist can also get total import java.util.*; public class Cart { List<Album> AlbumList = new ArrayList<Album>(); Main Method putting albums into addAlbum method public static void main(String[] args) { Cart cart1 = new Cart(); Album album1 = new Album("ye", 20); Album album2 = new Album("MBDTF", 16); cart1.addAlbum(album1); cart1.addAlbum(album2); System.out.println(cart1.getTotalAlbums()); cart1.displayAllAlbums(); } adding album to the arralist public void addAlbum(Album album) { AlbumList.add(album); } Unsure on how to display the album public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { System.out.println(AlbumList.get(i)); } } A: Do this. public void displayAllAlbums() { for (int i = 0; i < AlbumList.size(); i++) { Album album = AlbumList.get(i) System.out.println(album.getTitle() + " "+ album.getPrice()); } } Your Arraylist's objects are actually Album object. So when are accessing an ArrayList object via AlbumList.get(i) command, you're getting an Album object instance. So you pass it on to Album variable. Then access the private field via getter methods you've set up earlier! Cheers! Icon has Black Background It took me a while to just get the MailScanner link to show up, I had to even get WayToTheWeb to help me out with it! But now I've gotten the link to show and after having trouble getting the icon to show... its showing a black background! Anybody know whats up with it? I have tried to upload .jpg, .png, .gif versions. Redid the icon and made a static white background. I've done it all... I think. Anybody have

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b) The concentration profile of fenofibric acid in the brain.](PPAR2014-753587.005){#fig5} ###### The input parameters used during the simulation of plasma concentrations versus time profiles of fenofibric acid in rat model. Sr. number Input data Value ------------ ------------------------------------------- ------------------------ 1 MW 262.5 2 log⁡*P* 4.01 3 p*K* ~*a*~ (acidic) 3.56 4 Dose 27 mg/kg 5 Lower limit reference solubility (pH 7.4) 0.0294 mg/mL 6 Diffusion coefficient 0.825 × 10^−5^ cm^2^/s 7 Particle density 1.2 g/mL 8 Effective particle radius 5 µm 9 Effective permeability 7.66 × 10^−4^ cm/s 10 Physiology Fasted conditions 11 Absorption model Opt logD Model SA/V 12 Stomach transit time 0.1 h 13 Body weight 0.25 kg (Rat) 14 Clearance 1.1 mL/min/kg 15 Simulation time 36 h ###### The comparison of predicted and *in vivo* pharmacokinetic parameters of fenofibric acid. Sr. number Pharmacokinetic parameters *In vivo* Predicted Predicted/*in* *vivo* ratio ------------ ---------------------------- ---------------- ----------- ------------------------------- 1 AUC~0--*t*~ (µg h/mL) 274.68 ± 38.11 271.89 0.99 2 *C* ~max⁡~ (µg/mL) 20.49 ± 2.32 17.58 0.86 3 *T* ~max⁡~ (hours) 3.77 ± 0.64 3 0.80 4 *f* ~2~ Value 67.37 [^1]: Academic Editor: Constantinos Giaginis New 2019 Coachmen RV Clipper Ultra-Lite 16RBD This Clipper Ultra-Lite expandable 16RBD features front and rear expanding beds, and all the amenities you need to enjoy camping with family and friends. Step inside and see how much space you will have to enjoy with the rear expanding bed that is 54" x 74". Straight ahead there is a convenient bath which includes an angled shower, a toilet, and vanity with sink, plus overhead medicine cabinet. There is a kitchenette to your right as you enter featuring a two burner range, single sink, and storage overhead. A food pantry can be found opposite along side of the refrigerator with TV countertop above. In the front along the roadside find a dinette to enjoy your meals at, plus there is more seating opposite with a lounge including overhead storage. Both of these seating areas can easily become sleeping space if needed for family or extra guests. Also in front you will find an expanding bed that is 48" x 74". The expanding bed allows you to have the sleeping space you need without increasing your overall tow length. All this and more makes this a great camper for your family to enjoy! Options: BED END FAN LIGHT CLIPPER GRAPHICS DELUXE PKG FRONT WINDOW W/ ROCK GUARD RVIA SECOND BED END FAN LIGHT TOWABLE ESSENTIALS PKG TRAVEL EASY ROADSIDE ASSISTANCE What Our Customers Are Saying You will get my business always! Dear Mr. Beckley, I want to thank you and your entire staff for running a 1st class RV Dealership. As a fleet manager for Diamond Int. & Nabisco for 11 years in logging, trucking, and cookie delivery with combined fleets of 3,800 units on the road, when I find a quality organization A++ rated in my book, it is worthy of praise I met your sales team 6 years ago, so when I needed service on my Crossroads ... More » - Peter from Rock Hall, MD Rates and amount financed are determined by credit history. Your actual payments may vary. Plus tax, title and license. See dealer for details. Get Our Lowest Price Krazy Kelly's prices are so low, {mfg} won't allow us to display our price without you requesting it. So, please complete the simple form below to receive Krazy Kelly's Lowest Price! We'll get back with you as soon as possible, during normal business hours. Name Email Phone Zip Do you have a Trade In? Year Make Model# Mileage Amount Desired Tire Condition Last Resealed? Body Damage/Sidewall Delamination? If yes, please describe: Has the unit been smoked in? Leaks/Soft Floor/Soft Wall/Soft Ceiling/Discolored Paneling? If yes, please describe: Appliances in working order? Overall Condition Other Comments: It's ok to contact me about future discounts and events. (Easily unsubscribe at any time.) Coachmen RV is built upon a simple principle … “Dedicated to the enrichment of your life.” By providing you with long term value through all that we do, our focus is on providing a product with superior value and backing it through superior service and support. Once you become a Coachmen owner, we are committed to enhancing your Coachmen RV ownership and lifestyle experience… creating friends for life and memories that will last a lifetime. At Coachmen you will find a rich history of commitment from our Team Members. This commitment extends to our owners and in the pride we have for our brand. The close relationship that we share with our owners and our dealers is a quality that others have been trying to mimic over our 50 year history. Our goals and principles remain well in focus. We do create customers for life www.beckleysrvs.com Beckleys RVs is not responsible for any misprints, typos, or errors found in our website pages. Any price listed excludes sales tax, registration tags, and delivery fees. All prices may not include Beckley’s Camping Center’s 145 point pre-delivery inspection. Manufacturer-provided pictures, specifications and features may be used as needed. Inventory shown may be only a partial listing of the entire inventory. Please contact us at 800-615-6171 for availability as our inventory changes rapidly. All calculated payments are an estimate only and do not constitute a commitment that financing or a specific interest rate or term is available.Tip of the Week: How to Boost your Laptop’s Battery Power We all know the pains of having a laptop with low battery power, but sometimes it feels like you're perpetually plugging in your computer; even when it seems like the battery should last longer. These battery problems are common, but they aren’t an endgame for your laptop. There are several ways you can jumpstart your laptop’s battery. The purpose of a laptop is to remain portable while computing, and that isn’t possible if your battery is continuously failing. You shouldn’t have to be tied to an outlet on a daily basis in order to keep yourself productive. With these five tips, you should be able to keep your laptop alive significantly longer. Windows Updates Can Improve Battery Life If you want your computer to stay protected against the threats present in the online community, the latest patches for your operating system are a necessity. With Windows updates, you only receive these if you are using a supported operating system. Microsoft releases security updates and patches regularly, so you should have no problem maintaining the latest fixes for your operating system. As it turns out, these same updates can improve battery life. MTG can apply updates and patches to your systems remotely and securely, taking the responsibility of keeping your system secure off your shoulders. Optimize Your Power Settings In Windows 8.1, you have several options available to you to change your power settings. You can either choose a preset power plan, or build your own. To access these settings, look for the Power Options selection in the Control Panel. Some of the available options include: Screen brightness. How often the display turns off. When the computer sleeps. Where your computer’s resources are most allocated. Dim the Monitor Display Your laptop has several settings for brightness which can affect how long your battery lasts. Naturally, the higher the brightness on your monitor, the more energy it uses. According to CNet, the brightness of your monitor should be below half, or whatever is most comfortable for your eyes. In Windows 8.1, there is a slider which helps you adjust the brightness to the perfect degree. It can also help to turn down the keyboard brightness (if it lights up), if you’re able to. Turn Off Bluetooth Connections Even if you don’t use Bluetooth devices, just having Bluetooth activated can drain your battery. By shutting off Bluetooth, you can decrease the strain that it puts on your

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in a luxury hotel? You'll enjoy your best siesta yet, as well as plenty of spa and pool lounge time. *Swissotel Chicago: This location sets the bar for many guest services and amenities offered in downtown Chicago, and it happens to have great views while being located close to shopping mecca the Miracle Mile. On your day of rest, how about you indulge in a little gift-buying? That never hurt anyone! *La Pousada de Santa Fe: Located in downtown Santa Fe, this resort and spa puts you conveniently in the center of the action, as well as in the middle of historic Santa Fe charm. This location is just two blocks from art galleries and shopping. *The London West Hollywood: Hollywood glamour meets the high-quality expectations of staying at a London location. Always sophisticated, the London West Hollywood combines modern style with Hollywood charm. If personality and luxury are what you require, you've come to the right place. *The Winvian: This country spot tops our list of must-visits. This countryside location features stunning surroundings and awesome amenities that just urge you to kick back. Individual designer cottages are warm and inviting, and are planned to captivate plenty of personalities. Monday, September 21, 2009 Moms can get lonely, especially those child-rearing in more rural regions. From busy days where you get run down to days of nothing but routine, everyone needs a shoulder between vacations. CNN featured a special list of "friend types" that every mom should have around, and we don't think it's out of line to suggest that perhaps these friends might consider a vacation with you and your family. Why not? Imagine the benefits you'd reap from having two support systems, plus friends for the kids, while you enjoy a child-friendly resort that's just right for parents with a stressful routine at home. Soak in the pool, hang out at the spa, and zip off to the theatre or museums with your new friends to utilize your luxury hotel's excellent childcare facilities and trustworthy employees. You might not expect to relax so much when you take the kids along with you, but that's part of the fun! Without further ado, here are specific friend types to consider, which can make your life at home and on your vacation so much more enjoyable. *Been There, Done That: These friends are just right for the mom in need. When you are feeling stumped about a parenting problem or are stuck on the terrible twos, you have a support system to tell you exactly what you should (and should not) be doing. Isn't it nice not to second-guess yourself for once? *I'll Do Anything for You: The ultra-helpful friend who never says no mustn't be taken advantage of, even if she doesn't have kids of her own. She's enthusiastic and ready to take your kids to baseball, soccer, or basketball, or even help with the bake sale preparations. She's a keeper! *The Glam Girlfriend: When you're a mom, the looks can be put on the back burner--permanently. Trust this best friend to take you out on the town, bring you new brands, and give you advice on avoiding "mom jeans" forever. Use her for inspiration, advice, and hopefully her wardrobe as well. *Brutally Honest Friend: She tells it like it is. . . but shouldn't someone? While it's tough to have a friend like this around, it is nice to have a person on hand to ask for a dose of reality. Between kids' TV, meal-making, working, and planning, perspective can slide a bit. Have your friend jolt you into reality and make you get moving! Did you find a friend who sounds like someone on this list? If not, check out CNN's full friend guide, and then get to planning your vacation with the kids. Fairmont Southampton: This Bermuda location often has family offers that benefit busy families, and they also happen to boast one of the most impressive natural locations that the Caribbean has to offer. An indoor heated pool, spa location, and salon are all you need to spend some time unwinding. Acqualina Resort and Spa: Situated for prime dining and shopping, this resort right on the ocean has multiple children's programs to explore. While you and your new best friend bask in the Florida sun, you can rest assured that they'll be kept entertained and safe as you enjoy multiple ways to relax at the resort. Step one, the pool. Step two, your perfect guest suite. . . The Arrabelle, Vail Square: Take the ski and snowboard-loving teens on a vacation they'll never forget. . . this hotel is perfectly situated at the foot of the slopes in a European-inspired location. Snap plenty of pics of your family at this picturesque spot with first-class amenities and Rock Resort-level perks. Spring Creek Ranch: With close proximity to mountain trails, the Spring Creek Ranch attracts plenty of wildlife. Open yearly, this ranch has a view from every room, and is situated close to national parks just primed for exploring. Be sure to check out their award-winning Wilderness Spa. Saturday, September 19, 2009 The Guinness Book just released a mega-list of all the records broken, and it's surprising just how many new additions popped up in the new version. Why not have a fun and fascinating peek at just a few of the individuals who got the place of honor in the Guinness Book? *1,253 people dressed up like Smurfs in Ireland--the most in a single gathering. *A ball of plastic wrap fashioned by an 11-year-old boy from Michigan reached 11 feet across--and got him special recognition as well. *Brenden Adams of Washington, who has a 12th chromosome split in half, is 7 feet, 4.6 inches tall, and can't fit into cars. Since he's has knee replacements, he doesn't play basketball, preferring to bike and camp with his friends. *7.12 is the longest tuft of hair ever sprouted from someone's ear, and the honor has gone to Anthony Victor of India. Pushing the boundaries is a fascinating thing, and we can do that with travel, too. Instead of just booking a hotel and going to the city that sounds interesting, be sure to look up some curiosities in each city you visit. It'll really perk up your trip, especially when you take a ton of pics of the fascinating place that's caught your eye! Here are just a few suggestions of must-visit travel curiosities worldwide, and where to stay when you go to visit them: Montreal: St. Joseph's Oratory is a huge basilica located on Queen Mary Road, and its rumored healing powers have resulted in a giant collection of crutches and other memorabilia off the healed. Where to Stay: Try the Hotel Le St. James, which has old-fashioned appeal and modern convenience. Located in the heart of Montreal, it's a good place to stay if you'd like a little romance on your trip--and be close to the convention center as well. Tokyo: Go to a Cat Cafe while in Tokyo. The Curl Up Cafe features happily snoozing kitties on leather couches and chairs--and the 12 felines who hang out here commute with the owner every day. Where to Stay: The Park Hyatt Tokyo is located on the West Shinjuku and happens to be the hotel featured in Lost in Translation. The New York Grill is also one of Tokyo's best restaurants, so be sure to book early if you want to try it out. New York City: While NYC is known for its museums, the Museum of Sex is another experience entirely. Opened in 2002, it's not for the conservative or faint-of-heart, but the curious will get to browse through a collection of ever-changing displays. No one under 18 is permitted. Where to Stay: The Hotel Plaza Athenee in New York is located on the fashionable east side of Manhattan and is located close to Central Park and shopping destinations. You also have a chance to try global cuisine at their stunning eatery. Paris: Pere Lachaise might be a cemetery, but its unusual garden-like layout is the resting place of many a famed poet, artist, and entertainer. While you won't be alone when you make your trek to this location, it's a must-visit for any traveler in Paris.Where to Stay: The Four Seasons Hotel George V seems like you're staying in a fabulously luxurious private home, but you're actually not--the hotel decorators have lavished a great deal of money on these special rooms in a prime location. Thursday, September 17, 2009 Mong Thongdee has caught the world's attention with a story that's worthy of front-page news. The 12-year-old resident of Thailand might have construction worker parents making around $7 per day, but he also placed as the nation's best in a paper plane contest with a dart that floated 12.5 seconds in the air--long enough for him to be invited to represent Thailand in the Japanese origami airplane competition. Think there's a catch? There is, and of the type that we travelers might have temporarily faced while planning a zig-zagging trip to lesser known countries--visa issues that need to be worked out. It turns out that Mong lives on a temporary visa and cannot move freely between his country and others. Even for a boy who

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**) and residual neural network (**`maps.ResNet`**). It is also convenient to choose different training hyperparameters, such as loss types, metrics, optimizers, learning rate schedules, initializations and regularizations. In addition to solving differential equations, DeepXDE can also be used to approximate functions from multi-fidelity data [@meng2019composite], and learn nonlinear operators [@lu2019deeponet]. Customizability --------------- All the components of DeepXDE are loosely coupled, and thus DeepXDE is well-structured and highly configurable. In this subsection, we discuss how to customize DeepXDE to address new problem requirements, e.g., new geometry or network architecture. ### Geometry As we introduced above, DeepXDE has already supported 7 basic geometries and the CSG technique. However, it is still possible that the user needs a new geometry, which cannot be constructed in DeepXDE. In this situation, a new geometry can be defined as shown in Procedure \[code:geometry\]. Currently DeepXDE does not support accurately descriptions of complex curvilinear boundaries; however, a future extension could be incorporation of the non-uniform rational basis spline (NURBS) [@hughes2005isogeometric] for such representations. ``` {.Python linenos=""} class MyGeometry(Geometry): def inside(self, x): """Check if x is inside the geometry.""" def on_boundary(self, x): """Check if x is on the geometry boundary.""" def boundary_normal(self, x): """Compute the unit normal at x for Neumann or Robin boundary conditions.""" def periodic_point(self, x, component): """Compute the periodic image of x for periodic boundary condition.""" def uniform_points(self, n, boundary=True): """Compute the equispaced point locations in the geometry.""" def random_points(self, n, random="pseudo"): """Compute the random point locations in the geometry.""" def uniform_boundary_points(self, n): """Compute the equispaced point locations on the boundary.""" def random_boundary_points(self, n, random="pseudo"): """Compute the random point locations on the boundary.""" ``` ### Neural networks DeepXDE currently supports two neural networks: feed-forward neural network (**`maps.FNN`**) and residual neural network (**`maps.ResNet`**). A new network can be added as shown in Procedure \[code:nn\]. ``` {.Python linenos=""} class MyNet(Map): @property def inputs(self): """Return the net inputs.""" @property def outputs(self): """Return the net outputs.""" @property def targets(self): """Return the targets of the net outputs.""" def build(self): """Construct the network.""" ``` ### Callbacks It is usually a good strategy to monitor the training process of the neural network, and then make modifications in real time, e.g., change the learning rate. In DeepXDE, this can be implemented by adding a callback function, and here we only list a few commonly used ones already implemented in DeepXDE: - **`ModelCheckpoint`**, which saves the model after certain epochs or when a better model is found. - **`OperatorPredictor`**, which calculates the values of the operator applying on the outputs. - **`FirstDerivative`**, which calculates the first derivative of the outpus with respect to the inputs. This is a special case of **`OperatorPredictor`** with the operator being the first derivative. - **`MovieDumper`**, which dumps the movie of the function during the training progress, and/or the movie of the spectrum of its Fourier transform. It is very convenient to add other **`callback`** functions, which will be called at different stages of the training process, see Procedure \[code:callback\]. ``` {.Python linenos=""} class MyCallback(Callback): def on_epoch_begin(self): """Called at the beginning of every epoch.""" def on_epoch_end(self): """Called at the end of every epoch.""" ``` Demonstration examples {#sec:example} ====================== In this section, we use PINNs and DeepXDE to solve different problems. In all examples, we use the $\tanh$ as the activation function, and the other hyperparameters are listed in \[tab:hyperparameter\]. The weights $w_f$, $w_b$ and $w_i$ in the loss function are set as 1. The codes of all examples are published in GitHub. Example NN Depth NN Width Optimizer Learning rate \# Iterations --------- ---------- ---------- -------------- --------------- --------------- 1 4 50 Adam, L-BFGS 0.001 50000 2 3 20 Adam, L-BFGS 0.001 15000 3 3 40 Adam 0.001 60000 4 3 20 Adam 0.001 80000 5 4 20 L-BFGS - - : Hyperparameters used for the following 5 examples. “Adam, L-BFGS” represents that we first use Adam for a certain number of iterations, and then switch to L-BFGS. The optimizer L-BFGS does not require learning rate, and the neural network is trained until convergence, so the number of iterations is also ignored for L-BFGS.[]{data-label="tab:hyperparameter"} Poisson equation over an L-shaped domain ---------------------------------------- Consider the following two-dimensional Poisson equation over an L-shaped domain $\Omega = [-1,1]^2\setminus [0,1]^2$: $$\begin{aligned} -\Delta u(x,y) &= 1,\quad (x,y)\in \Omega, \\ u(x,y) &= 0, \quad (x,y)\in \partial \Omega.\end{aligned}$$ We choose 1200 and 120 random points drawn from a uniform distribution as $\mathcal{T}_f$ and $\mathcal{T}_b$, respectively. The PINN solution is given in \[fig:Poisson:Lshape\]B. For comparison, we also present the numerical solution obtained by using the spectral element method (SEM) [@Karbook] (\[fig:Poisson:Lshape\]A). The result of the absolute error is shown in \[fig:Poisson:Lshape\]C. ![Example 4.1. Comparison of the PINN solution with the solution obtained by using spectral element method (SEM). (**A**) the SEM solution $u_{SEM}$, (**B**) the PINN solution $u_{NN}$, (**C**) the absolute error $|u_{SEM} - u_{NN}|$.[]{data-label="fig:Poisson:Lshape"}](Poisson.pdf){width="\textwidth"} RAR for Burgers equation ------------------------ We first consider the 1D Burgers equation: $$\begin{gathered} \frac{\partial u}{\partial t} + u \frac{\partial u}{\partial x} = \nu \frac{\partial^2 u}{\partial x^2}, \quad x\in[-1, 1], ~ t \in[0, 1], \\ u(x, 0) = -\sin(\pi x), \quad u(-1, t) = u(1, t) = 0.\end{gathered}$$ Let $\nu = 0.01/\pi$. Initially, we randomly select 2500 points (spatio-temporal domain) as the residual points, and then 40 more residual points are added adaptively via RAR developed in \[sec:rar\] with $m = 1$ and $\mathcal{E}_0 = 0.005$. We compare the PINN solution with RAR and the PINN solution based on 2540 randomly selected training data (\[fig:burgers\] A and B), and demonstrate that PINN with RAR can capture the discontinuity much better. For a comparison, the finite difference solutions using central difference scheme for space discretization and forward Euler scheme for time discretization for the Burgers equation in the conservative form are also shown in \[fig:burgers\]A. Here, we also present two examples for the residual points added via the RAR method. As shown in \[fig:burgers\] C and D, the added points (green crosses) are quite close to the sharp interface, which indicates the effectiveness of RAR. We further solve the following two-dimensional Burgers equation using the RAR: $$\begin{gathered} \partial_t u + u \partial_x u + v \partial_y u = \frac{1}{\mbox{Re}} (\partial^2_x u + \partial^2_y u),\\ \partial_t v + u \partial_x v + v \partial_y v = \frac{1}{\mbox{Re}} (\partial^2_x v + \partial^2_y v),\\ x, y \in [0, 1], ~ \mbox{and} ~t \in [0, 1],\end{gathered}$$

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-1.\end{array}\right.$$Then $\mathrm{ct}_{\kappa }$ is an odd function, satisfies $\lim_{t\rightarrow 0^{-}}\mathrm{ct}_{\kappa }=-\infty ,$ and is strictly decreasing on $\left( 0,\infty \right) .$ Let $\Lambda _{N}$ be the Lagrangian family along $\gamma _{v}$ from Equation \[dfn of Lambda\_N\]. Let $S$ be the corresponding Riccati operator. Observe that at $t=0,$ the restriction of $S$ to the second summand in (\[dfn of Lambda\_N\]) coincides with the shape operator $S_{v}$ of $N$. If the conclusion is false, there are $\left\{ J_{1},\ldots ,J_{k}\right\} \subset \Lambda _{N}$ with $\left\{ J_{i}\left( 0\right) \right\} _{i=1}^{k}$ orthonormal so that $$\begin{aligned} J_{i}^{\prime }\left( 0\right) &=&S\left( J_{i}\left( 0\right) \right) \text{ and } \\ \left\vert \Sigma _{i=1}^{k}\left\langle S\left( J_{i}\left( 0\right) \right) ,J_{i}\left( 0\right) \right\rangle \right\vert &\geq &k\cdot \mathrm{ct}_{\kappa }\left( \mathrm{FocalRadius}\left( N\right) -\alpha \right) ,\end{aligned}$$for some $\alpha \in \left( 0,\mathrm{FocalRadius}\left( N\right) \right) .$ After possibly replacing $v$ with $-v$, we may assume that $$\begin{aligned} \Sigma _{i=1}^{k}\left\langle S\left( J_{i}\right) ,J_{i}\right\rangle |_{0} &\leq &-k\cdot \mathrm{ct}_{\kappa }\left( \mathrm{FocalRadius}\left( N\right) -\alpha \right) \\ &=&k\cdot \mathrm{ct}_{\kappa }\left( \alpha -\mathrm{FocalRadius}\left( N\right) \right) ,\text{ since }\mathrm{ct}_{\kappa }\text{ is an odd function} \\ &<&0.\end{aligned}$$It follows from Lemma \[sing soon Ric\_k Lemma\] that for all $t_{1}\in \left( 0,\mathrm{FocalRadius}\left( N\right) \right) $ there is a $k$–dimensional subspace $W_{t_{1}}\subset \Lambda _{N}$ so that $$\mathrm{Tr}\left( S|_{W_{t_{1}}}\right) \leq k\cdot \mathrm{ct}_{\kappa }\left( \alpha -\mathrm{FocalRadius}\left( N\right) +t_{1}\right) .$$Since $\alpha -\mathrm{FocalRadius}\left( N\right) <0$ and $\lim_{t\rightarrow 0^{-}}\mathrm{ct}_{\kappa }=-\infty ,$ $\Lambda _{N}$ has a singularity by time $\mathrm{FocalRadius}\left( N\right) -\alpha .$ This is a contradiction because $\Lambda _{N}$ is nonsingular on the interval $\left( 0,\mathrm{FocalRadius}\left( N\right) \right) $. Let $M$ be a complete Riemannian $n$–manifold with $Ric_{k}$ $\geq 0,$ and let $N$ be any closed submanifold of $M$ with $\dim \left( N\right) \geq k$ and infinite focal radius. Let $v$ be any unit normal vector to $N.$ As in Equation \[dfn of Lambda\_N\] we let$$\Lambda _{N}\equiv \left\{ J|J\left( 0\right) =0\text{, }J^{\prime }\left( 0\right) \in \nu _{\gamma _{v}\left( 0\right) }\left( N\right) \right\} \oplus \left\{ J|J\left( 0\right) \in T_{\gamma _{v}\left( 0\right) }N\text{ and }J^{\prime }\left( 0\right) =\mathrm{S}_{v}J\left( 0\right) \right\} .$$We set$$\begin{aligned} \mathcal{V} &\equiv &\left\{ J|J\left( 0\right) =0\text{, }J^{\prime }\left( 0\right) \in \nu _{\gamma _{v}\left( 0\right) }\left( N\right) \right\} \text{, and } \\ W &\equiv &\left\{ J|J\left( 0\right) \in T_{\gamma _{v}\left( 0\right) }N\text{ and }J^{\prime }\left( 0\right) =\mathrm{S}_{v}J\left( 0\right) \right\} .\end{aligned}$$ Since $N$ has no focal points, $\Lambda _{N}$ has no singularities on $\mathbb{R}\setminus \left\{ 0\right\} $. Thus for all $J\in \Lambda _{N}\setminus \left\{ 0\right\} $ and all $t\in \mathbb{R}\setminus \left\{ 0\right\} ,$ $J\left( t\right) \neq 0.$ By replacing $v$ with $-v$, if necessary, we may assume that $$\mathrm{Tr}\left( \mathrm{S}|_{W}\left( 0\right) \right) \leq 0. \label{inti nonpos}$$ By Part 3 of Lemma \[sing soon Ric\_k Lemma\], it follows that $t\longmapsto \Lambda \left( t\right) $ splits orthogonally into the parallel distributions $$\Lambda \left( t\right) \equiv W\left( t\right) \oplus \mathcal{V}\left( t\right) ,$$and every field in $W$ is parallel. Since we started with an arbitrary normal vector$,$ $N$ is totally geodesic, and Parts 1 and 4 are proven. Part 2 is a consequence of the Hopf-Rinow Theorem (see Part e of Theorem 2.8 on page 147 of [@doCarm]). Part 3 follows by observing that $\exp _{N}^{\perp }:\left( \nu \left( N\right) ,\left( \exp _{N}^{\perp }\right) ^{\ast }\left( g\right) \right) \longrightarrow \left( M,g\right) $ is a local isometry, so as in the proof of Cartan-Hadamard, $\exp _{N}^{\perp }$ is a cover (see Lemma 3.3 on page 150 of [@doCarm] or Lemma 5.6.4 of [@Pet]). Part 5 follows from the fact that every field in $W$ is parallel. To prove Part 6, let $\mathrm{II}$ be the second fundamental form of $\mathrm{image}\left( \Phi \right) .$ Since $$\gamma _{V\left( s\right) }:t\longmapsto \Phi \left( t,s\right) =\exp _{c\left( s\right) }^{\perp }\left( tV\left( s\right) \right)$$is a geodesic, $\mathrm{II}\left( \frac{\partial \Phi }{\partial t},\frac{\partial \Phi }{\partial t}\right) =0,$ and since $\frac{\partial \Phi }{\partial s}$ is parallel along $\gamma _{V\left( s\right) },$ $\mathrm{II}\left( \frac{\partial \Phi }{\partial t},\frac{\partial \Phi }{\partial s}\right) =0.$ To determine $\mathrm{II}\left( \frac{\partial \Phi }{\partial s},\frac{\partial \Phi }{\partial s}\right) ,$ observe that the lift, $\left( \exp _{N}^{\perp }\right) ^{\ast }\left( \frac{\partial \Phi }{\partial s}\right) ,$ of $\frac{\partial \Phi }{\partial s}$ via $\exp _{N}^{\perp },$ is a basic horizontal, geodesic field for the Riemannian submersion$$\pi :\left( \nu \left( N\right) ,\left( \exp _{N}^{\perp }\right) ^{\ast }\left( g\right) \right) \longrightarrow N.$$Thus $\mathrm{II}\left( \frac{\partial \Phi }{\partial s},\frac{\partial \Phi }{\partial s}\right) =\nabla _{\frac{\partial \Phi }{\partial s}}\frac{\partial \Phi }{\partial s}\equiv 0,$ and the image of $\Phi $ is totally geodesic. Since $\frac{\partial \Phi }{\partial s}$ is a parallel Jacobi field along $\gamma _{V\left( s\right) },$ the image of $\Phi $ is flat. To prove Part 7, consider a $V\in \mathcal{V}$ along with orthonormal parallel fields $J_{1},\ldots ,J_{k-1}$ in $W.$ Since $\mathrm{sec}\left( \gamma _{v}^{\prime },J_{i}\right) \equiv 0$ and $\mathrm{Ric}_{k}\geq 0,$

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www.brainwy.com/tracker/PyDev/645 # if __pydevd_id__ is None, recalculate it... also, use an heuristic # that gives us always the same id for the thread (using thread.ident or id(thread)). raise AttributeError() except AttributeError: tid = _get_or_compute_thread_id_with_lock(thread, is_current_thread=True) return tid def get_thread_id(thread): try: # Fast path without getting lock. tid = thread.__pydevd_id__ if tid is None: # Fix for https://www.brainwy.com/tracker/PyDev/645 # if __pydevd_id__ is None, recalculate it... also, use an heuristic # that gives us always the same id for the thread (using thread.ident or id(thread)). raise AttributeError() except AttributeError: tid = _get_or_compute_thread_id_with_lock(thread, is_current_thread=False) return tid def set_thread_id(thread, thread_id): with _thread_id_lock: thread.__pydevd_id__ = thread_id #======================================================================================================================= # Null #======================================================================================================================= class Null: """ Gotten from: http://aspn.activestate.com/ASPN/Cookbook/Python/Recipe/68205 """ def __init__(self, *args, **kwargs): return None def __call__(self, *args, **kwargs): return self def __enter__(self, *args, **kwargs): return self def __exit__(self, *args, **kwargs): return self def __getattr__(self, mname): if len(mname) > 4 and mname[:2] == '__' and mname[-2:] == '__': # Don't pretend to implement special method names. raise AttributeError(mname) return self def __setattr__(self, name, value): return self def __delattr__(self, name): return self def __repr__(self): return "<Null>" def __str__(self): return "Null" def __len__(self): return 0 def __getitem__(self): return self def __setitem__(self, *args, **kwargs): pass def write(self, *args, **kwargs): pass def __nonzero__(self): return 0 def __iter__(self): return iter(()) # Default instance NULL = Null() def call_only_once(func): ''' To be used as a decorator @call_only_once def func(): print 'Calling func only this time' Actually, in PyDev it must be called as: func = call_only_once(func) to support older versions of Python. ''' def new_func(*args, **kwargs): if not new_func._called: new_func._called = True return func(*args, **kwargs) new_func._called = False return new_func # Protocol where each line is a new message (text is quoted to prevent new lines). # payload is xml QUOTED_LINE_PROTOCOL = 'quoted-line' ARGUMENT_QUOTED_LINE_PROTOCOL = 'protocol-quoted-line' # Uses http protocol to provide a new message. # i.e.: Content-Length:xxx\r\n\r\npayload # payload is xml HTTP_PROTOCOL = 'http' ARGUMENT_HTTP_PROTOCOL = 'protocol-http' # Message is sent without any header. # payload is json JSON_PROTOCOL = 'json' ARGUMENT_JSON_PROTOCOL = 'json-dap' # Same header as the HTTP_PROTOCOL # payload is json HTTP_JSON_PROTOCOL = 'http_json' ARGUMENT_HTTP_JSON_PROTOCOL = 'json-dap-http' ARGUMENT_PPID = 'ppid' class _GlobalSettings: protocol = QUOTED_LINE_PROTOCOL def set_protocol(protocol): expected = (HTTP_PROTOCOL, QUOTED_LINE_PROTOCOL, JSON_PROTOCOL, HTTP_JSON_PROTOCOL) assert protocol in expected, 'Protocol (%s) should be one of: %s' % ( protocol, expected) _GlobalSettings.protocol = protocol def get_protocol(): return _GlobalSettings.protocol def is_json_protocol(): return _GlobalSettings.protocol in (JSON_PROTOCOL, HTTP_JSON_PROTOCOL) class GlobalDebuggerHolder: ''' Holder for the global debugger. ''' global_dbg = None # Note: don't rename (the name is used in our attach to process) def get_global_debugger(): return GlobalDebuggerHolder.global_dbg GetGlobalDebugger = get_global_debugger # Backward-compatibility def set_global_debugger(dbg): GlobalDebuggerHolder.global_dbg = dbg if __name__ == '__main__': if Null(): sys.stdout.write('here\n') Association of ER-alpha gene polymorphism with metabolic phenotypes in Chinese Hans. Recently, two polymorphisms (rs1884052 and rs3778099) of estrogen receptor alpha (ER-alpha) gene were identified as being associated with primary quantitative bone mineral density (BMD) in a genome-wide association (GWA) study in Framingham cohorts. In this study we aimed at investigating the association of rs1884052 and rs3778099, and another polymorphism (rs2234693) located at intron 1 of the ER-alpha gene with BMD, body mass index (BMI), glucose, triglyceride, and total cholesterol (CHO) levels in Chinese Hans. We recruited 425 consecutive adult volunteers who had a physical examination in the Jinan Maternity and Child Care Hospital. We did not observe significant association of rs1884052 and rs3778099 with BMD, BMI, glucose, triglyceride, and total cholesterol (CHO) levels. For rs2234693, increased levels of BMD for hip, spine or whole-body regions were consistently observed in TT/TC genotype carriers than in CC genotype carriers, although the board line significance diminished after adjusting for age and gender. However, significant association of rs2234693 with glucose and CHO levels were observed in our sample. Subjects with TC/CC genotypes were associated with an increased level of glucose (p = 0.013) and CHO (p = 0.032) levels than subjects with TT genotypes. In conclusion, we did not confirm the association of rs1884052 and rs3778099 with BMD originally discovered in a GWA study; however, we made novel discoveries that rs2234693 was associated with glucose and CHO levels in Chinese Hans.Matt Forte exits early with knee injury; will not return Bears running back Matt Forte has left Sunday’s game against the Chiefs because of a right knee injury. Forte was injured on a run deep in Chicago territory midway through the first quarter, when Kansas City’s Derrick Johnson hit him in the knee. He stayed on the ground for several minutes as medical personnel tended to him. The league’s third-leading rusher walked off the field on his own power and stayed on the sideline for a few minutes before heading to the locker room.Do you think there can be parallel universes? The parallels universes have been a controversial topic for many years there are many physics theories established by big minds like Albert Einstein with his string theory were pose a possibility of other parallels dimensions. There are many investigations about this topic and also in the world of art and cinema, we can see many examples of it like Stranger things, The Chronicles of Narnia, Doom etc. These parallels universes can be explained by the paradox of Schrödinger, It describes that the life of a cat depends on a particle, if the particle disintegrates the cat dies but if the particle does not disintegrate the cat will remain alive. that means that maybe in this world you are a veterinary but in another world you are a carpenter, because you did not have the same chance in both universes, and small variations can create another new reality.I think that we have still had a lot of things to discover about this beautiful universe. Do you believe in parallels universes? or is just a sci-fiction thing? February 17, 2018, 1:36 pm Responses (88) This topic has just been magnified by Hollywood and other several books but has not been proven. Even the black hole hasn't been established. But if ever

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if what ever happens is as you expected it to. By exploring the functionality you probably execute existing test cases (happy path) but you will also test paths not covered in test cases (perhaps resulting in new (automated) test cases to be executed). The more you know about the product that is developed and the more you are experienced with testing, the better the result of the exploratory test. Is exploratory testing only for testers? From my perspective I would say: No, not totally! Perhaps a exploratory test is at best when executed by a tester since our testing skills and mindset would help when testing. But like I mentioned before: The more you know about the product that is developed…. That would indicate that everyone from developers to consultants could be involved in exploratory testing. Not only testers have knowledge about the product developed. For example: Consultants usually know how one or more customers use the product. This knowledge can be of great value when they are testing. Not all developers and tester will have this knowledge. Developers for example know how they developed the product and where to find “weak” spots in the application. They can point them out for you to test, but can also test these themselves, learn, fix bugs and deliver a better (part of the) product. Developers can also practice exploratory testing when doing a code review. Besides literally only reviewing the code, click trough the component if possible and look for some simple bugs. By saying that I’m not saying that testers are obsolete, I think testers just shouldn’t be bothered with finding bugs that are blocking the flow just after two mouse clicks. Why exploratory testing is so important: Following test scripts is repetitive work, testing a new release for the second time by following a testscript will probably not give you new results. It’s most unlikely that these test will now suddenly fail. By exploring (parts of) the system under test you will probably find new results, find new testcases, write them down and perhaps automate them. The first thing I do when I’m done with testing a new version of our application via a manual regression testscript is exploratory testing. This can also be done when your in an agile team and the user store is completed because it reached its definition of done, after that there is nothing holding you back to explore the functionality and put it to done when you as tester are completely satisfied with the result. How to overcome some of the downsides of Exploratory testing Unfortunately exploratory testing also has some downsides. The main problem I experienced was that you can get easily lost in time when exploratory testing, you’ll have to watch out that it down not result in some kind of exhaustive testing. Best practice for me is to time box each exploratory testing session. For each time frame I pick one or two (when testing interaction) particular parts of the system under test, set some objectives what to test, write down or log my findings and when the time is up I move on to the next test. An easy and lightweight tool to help you with creating sessions for exploratory testing is Sessiontester. As described by their website: “It has a timer so you limit your test sessions to a particular length, and it provides an easy way to record session notes.” When to apply exploratory testing Here is a summary of situations in which you could prefer applying exploratory testing: When testing with test scripts is completed but you do not feel totally confidant with the delivered functionality. When fast feedback about a functionality is needed. When the functionality is already mature and no or minor changes has been made. When there is no time to execute a (scripted) functional test but feedback is still required. When testing the frontend of a webapplication with multiple browsers (Internet explorer, Firefox, Safari etc.).CLD-290 NOT PRECEDENTIAL UNITED STATES COURT OF APPEALS FOR THE THIRD CIRCUIT ___________ No. 14-1741 ___________ IN RE: ALTON D. BROWN, Petitioner ____________________________________ On a Petition for Writ of Mandamus from the United States District Court for the Eastern District of Pennsylvania (Related to E.D. Pa. Civ. No. 2-07-cv-03771) ____________________________________ Submitted Pursuant to Rule 21, Fed. R. App. P. June 26, 2014 Before: FUENTES, JORDAN and SHWARTZ, Circuit Judges (Opinion filed: July 2, 2014) _________ OPINION _________ PER CURIAM Pro se litigant Alton Brown has filed a petition for a writ of mandamus, requesting that we order the District Judge to recuse. For the reasons set forth below, we will deny the petition. Brown filed the underlying case in September 2007, and it has developed a protracted history. With respect to the particular petition at bar, Brown alleges that the District Judge is involved in a wide-ranging conspiracy with lawyers, corrections officials, and other judges “to deny him due process and equal protection of the laws.” He also claims more generally that the District Judge is biased and prejudiced against him. Brown filed a motion for recusal in February 2014, which the District Court denied. He relies on 28 U.S.C. § 455 to support this petition for a writ of mandamus.1 Mandamus is a drastic remedy that is available only in extraordinary situations. See Kerr v. U.S. Dist. Court, 426 U.S. 394, 402 (1976). To qualify for this exceptional relief, a petitioner must prove that his right to issuance of the writ is clear and indisputable. See id. at 403. Brown falls far short of this high bar. Brown’s petition implicates two related subsections of § 455, the statute concerning recusal: subsection (a) requires recusal when a judge’s impartiality might reasonably be questioned, and subsection (b) requires recusal when the judge has a personal bias or prejudice concerning a party. Most of the acts Brown cites to demonstrate the District Judge’s alleged conspiracy and bias — denying him leave to amend or supplement his complaint, appointing him counsel, and managing discovery, for instance — are examples of prototypical judicial decision making. And mere dissatisfaction with those rulings does not warrant recusal. See Securacomm Consulting, Inc. v. Securacom Inc., 224 F.3d 273, 278 (3d Cir. 2000) (“We have repeatedly stated that a party’s displeasure with legal rulings does not form an adequate basis for recusal.”). Brown also claims that the District Judge was hostile to him, remarking that he was wasting valuable court resources during discovery proceedings. But even were 1 He also purports to bring the petition pursuant to 28 U.S.C. § 144. But mandamus relief is not available here under § 144, because Brown may still take an appeal from the order denying recusal after final judgment is entered. See In re Sch. Asbestos Litig., 977 F.2d 764, 774-76 (3d Cir. 1992). 2 this comment made in the most impatient of tones, it would not establish bias sufficient to mandate recusal. See Liteky v. United States, 510 U.S. 540, 555-56 (1994) (“Not establishing bias or partiality, however, are expressions of impatience, dissatisfaction, annoyance, and even anger, that are within the bounds of what imperfect men and women . . . sometimes display.). Brown also seems to suggest that the District Judge must recuse because she is a defendant in one of his several active lawsuits against judges, lawyers, and corrections officials. Again, it is well-established that such a situation does not independently warrant recusal. See Azubuko v. Royal, 443 F.3d 302, 304 (3d Cir. 2006); In re Taylor, 417 F.3d 649, 652-53 (7th Cir. 2005). Lastly, conclusory allegations of conspiracy make up the balance of Brown’s petition, but recusal is not required on the basis of “unsupported, irrational, or highly tenuous speculation.” In re United States, 666 F.2d 690, 694 (1st Cir. 1981). Because Brown has not shown that § 455 mandates the District Judge’s recusal, he has failed to establish a clear and indisputable right to the mandamus relief he seeks. His petition is denied. 3 /* * Copyright (c) 2011 Apple Inc. All rights reserved. * * @APPLE_OSREFERENCE_LICENSE_HEADER_START@ * * This file contains Original Code and/or Modifications of Original Code * as defined in and that are subject to the Apple Public Source License * Version 2.0 (the 'License'). You may not use this file except in * compliance with the License. The rights granted to you under the License * may not be used to create, or enable the creation or

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. The club had to wait until 1970 for another promotion, when they were promoted as Liga Alef champions. They narrowly avoided relegation in the 1970–71 season, finishing above relegated Maccabi Petah Tikva on goal difference. However, they were relegated the following season after finishing bottom. This time they bounced back immediately as Liga Alef runners-up, and finished 13th in 1973–74, a single point above the relegation zone. Although 1974–75 saw the club finish in their highest-ever position, 7th, they were relegated the following season. The club made a second immediate return to the top flight as Liga Artzit (the new second division) champions, but were relegated again in 1979, marking their last appearance to date in the top division. In 1986 and 1989 the club won the Liga Artzit Toto Cup. In 1994 they were deducted 12 points after being found guilty of match-fixing in a league game against Hakoah Ramat Gan. They were relegated to the third tier in 1997, and following league restructuring in 1999, sank into the fourth division. They were relegated again to Liga Bet in 2003. In 2006, All the football clubs from Hadera merged into one club called Hapoel Ironi Eran Hadera, and at the end of the 2007–08 season the club won the South A division of Liga Bet and were promoted back to Liga Alef. In the 2009–10 season, the club battled for promotion to Liga Leumit and was leading 70% of the season at 1st place. However, they did not achieved promotion after finished 3rd place at Liga Alef South division. in next season of 2010–11 they changed division to the North, and it was a beginning of bad financial problem, and with small budget they needed to build the club from the beginning. at that season, the manager was Ami Elhadad, one of the players who played for the club in the 1970s. at the end of the season they finished in the 8th place. The 2011–12 season was one of their worst seasons, as they finished in the 14th place and had to play-off against Ihud Bnei Maksur from Liga bet. Hadera won the relegation play-off 2–1 after goals scored by Momo Nistel and Elias Zana. during the season, the club saw changes in the manager position, when Ami Elhadad resigned from the club, and replaced by the youth manager, Yohanan Israelov, who did not finish the season as well, as Itzik Ben Tora managed the club in the last two games. . In the 2012–13 season, Eyal Amar, former player for the club, took over the manager position, after three seasons as the manager of local rivals, F.C. Givat Olga. the club started the season well, when showed good games. However, at the end of season they finished in the 7th place. manager Eyal Amar left the club and returned to Givat Olga. In the 2013–14 season, the club was managed by Ahmed Wahab as manager and Yosef Mogiliovsky as assistant-manager, and placed 8th after the first round of the league (15 games). After Ahmed Wahab left the club with his son, Barkat, due to financial problems, and Kobi Badash left for Hapoel Migdal HaEmek, Hadera signed new manager, Ron Keler, which trained the youth section of the club, and finished the season in the 7th place, 6 points short of the promotion play-offs. In The 2014–15 season the started with Gil Fishel as new manager. but after 10 games the manager resign because of financial problems. and after that Sasha Feldman who was a player of the club take care of coaching team. after 4 games he left the club and in the derby with MS Givat olga Itsik Ben Tora stand on the line 1 match. than Yohanan Izraelov return to training the team he was coaching only 5 games and left too. Ron Keller who trained last season take care the club and made a success with team and reach 9th place at Liga alef north. and was the first to win derby in last match 1–0 on Givat Olga. In season 2015–16 was talking to take new management of the team but the talks didn't bring anything and Yoav Kobi still the owner of the club. The team signed new coach past player Momo Nistel that trained before Beitar Pardes Hana with success. In season 2016–17 was big day in the club. The team promote to Liga Leumit the second tier in Israel. after finishing 1st place in the league. It was first time after 20 seens it was the last time to play in second tier. In season 2017–18, the club was promoted again to the Israeli Premier League for the first time after 40 years from the second place of Liga Leumit. In the next season, Hapoel Hadera made a big sensation in the Premier League and secured the place in the championship playoff, what brought the club to improve their previous record in the First Division, seventh place, and finish the season in the sixth place. Current squad As to 6 February 2020 Honours League Cup competitions References 50 Years of Sports and More in Hadera, Efraim Frank (Israel), 2004, pp. 190–227 External links Official Site Hapoel Hadera Eran Israel Football Association Category:Football clubs in Israel Category:Sport in Hadera Hadera Category:Association football clubs established in 1949 Category:1949 establishments in IsraelQ: Drawing lines between arbitrary words on a page I try to get rid of tree-dvips and look for a way to do the following: Circle an arbitrary word on the page and draw an arrow from some other position at the page towards this circled word. In tree-dvips one can just simply declare a word a node and then use connection directives. I guess this can be done with pgf somehow, but the nodes seem to require a position in a coordinate system. This is the tree-dvips code: \documentclass{scrbook} \usepackage{tree-dvips} \begin{document} \begin{tabular}{lllllll} \node{bazas}{bāz-a\v{s}} & agar & mi-xāh-i & fardâ & \node{blk1}{} & bo-kon-i\\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' {\makedash{1pt} \nodeoval{bazas} \abarnodeconnect[-18pt]{blk1}{bazas}} \end{document} A: run it with xelatex \documentclass{scrbook} \usepackage{fontspec} \usepackage{pst-node} \begin{document} \begin{tabular}{lllllll} \ovalnode[linestyle=dashed]{bazas}{bāz-a\v{s}} & agar & mi-xāh-i & fardâ & \rnode{blk1}{~} & bo-kon-i\\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' \ncbar[linestyle=dashed,arrows=->,angle=-90,arm=20pt]{blk1}{bazas} \end{document} A: Addition: A solution with tikz: \documentclass{scrbook} \usepackage{tikz} \usetikzlibrary{shapes.geometric} \begin{document} \begin{tabular}{lllllll} \tikz[remember picture,baseline]\node[anchor=base,ellipse,draw](bazas){baz-a\v{s}}; & agar & mi-xah-i & fardâ % & \node{blk1}{} & \tikz[remember picture,overlay] \draw[->,dashed] (0,0) -- ++(0pt,-4.75ex) coordinate(tmp1) -- (bazas |- tmp1) -- (bazas |- tmp1) -- (bazas); & bo-kon-i \\ open-\textsc{3sg} & if & \textsc{ipf}-want-\textsc{2sg} & tomorrow & {} & \textsc{sbj}-do-\textsc{2sg}\\ \end{tabular}\\[2ex] `If you want to open it tomorrow \ldots' \end{document} Science

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84\<.012.170.50--9.360.300.880.65--1.190.41Education Primary\-\-\-\-\-\-\-\-\-\-\-- Secondary0.750.54--1.020.070.730.52--1.010.064.830.71--32.940.110.760.56--1.050.09 Tertiary1.120.73--1.710.601.180.76--1.830.471.310.17--10.400.790.970.63--1.480.88Housing Living at home^a^\-\-\-\-\-\-\-\-\-\-\-- Living at home^b^1.601.01--2.530.041.701.04--2.780.041.440.30--6.900.651.721.08--2.740.02 Assisted living0.710.38--1.310.270.900.47--1.710.75\<.01\<.0010.960.610.33--1.130.12 Care home0.680.37--1.240.210.780.39--1.570.480.080.01--0.48\<.010.510.28--0.930.03Use of Analgesics^c^2.171.48--3.16\<.012.131.42--3.18\<.012.620.49--13.982.622.751.88--4.03\<.01BMI Adiposity1.140.71--1.840.601.170.71--1.920.530.240.02--2.810.251.480.92--2.390.11 Overweight1.210.89--1.650.221.190.86--1.630.303.140.71--13.990.131.371.01--1.860.05 Normal weight\-\-\-\-\-\-\-\-\-\-\-- Underweight0.740.29--1.910.530.550.20--1.530.252.880.07--114.060.571.360.05--3.480.52Barthel Index^d^0.990.98--1.010.190.990.98--1.010.301.010.96--1.070.640.990.98--1.010.27Depressive symptoms^e^1.151.08--1.22\<.011.141.07--1.22\<.011.421.01--1.990.041.141.07--1.21\<.01MMSE^f^0.600.35--1.030.06\-\-\-\-\--0.690.41--1.170.17Notes: *OR* Odds Ratio, Alpha was set to 0.05^a^Participants without care support^b^Participants with care support^c^use of analgesics: dichotomized^d^Barthel Index: score 0--100^e^GDS score 0--15^f^MMSE: score 0--30, cut-off ≤25 for mild cognitive impairment, \> 25 no cognitive impairment Model 1 -- Overall pain ratings {#Sec11} ------------------------------- In model 1 we tested the association of demographic and clinical characteristics on the overall sample. Male sex was statistically significantly associated with lower PRS (OR 0.61, 95% CI 0.45--0.84) while contrary associations were found for age. Individuals between 90 to 94 years of age scored significantly lower in the PRS (OR 0.65, 95% CI 0.48--0.88) than the younger age bracket. Considering the housing situation higher PRS was significantly associated with participants living at home with care support. There is a 1.6 higher possibility of experiencing pain for this group than living at home without care support (OR 1.60, 95% CI 1.01--2.53). There was also a significant association for analgesics. Participants receiving analgesics experience twice as much pain (OR 2.17, 95% CI 1.48--3.16). Furthermore higher PRS was significantly associated with depression (OR 1.15, 95% CI 1.08--1.22). No significant evidence showed for differences in education, BMI or Barthel-Index. Model 2 and 3 - MMSE status {#Sec12} --------------------------- In model two and three we divided the sample in NCI and MCI participants and found significant associations for both groups: Again male sex was significantly associated with lower pain ratings for both groups (NCI: OR 0.61, 95% CI 0.44--0.85 and MCI: OR 0.21, 95% CI 0.05--0.93). Significant associations for age appeared according to model 1 for NCI aged 90 to 94 years old. The older age group scored significantly lower in the PRS (OR 0.61, 95% CI 0.44--0.84). No association with age was found for the group the MCI-participants. Concerning the housing situation living at home with care support was significantly associated with higher ratings on the PRS for NCI (OR 1.70, 95% CI 1.04--2.78) and significantly associated with lower ratings on the PRS for MCI-participants living in a care-home (OR 0.08, 95% CI 0.01--0.48). Also for both groups higher PRS was significantly associated with depression (NCI: OR 1.14, 95% CI 1.07--1.22 and MCI: OR 1.42, 95% CI 1.01--1.99). Significant associations for analgesics were found for NCI. Those taking analgesics reported twice as much pain (OR 2.12, 95% CI 1.42--3.18). No significant figures appeared for education, BMI or Barthel-Index. Model 4 - impairment in daily activities {#Sec13} ---------------------------------------- In model 4 we analyzed the impairment in daily activities for the overall sample. Again we found a significant association for lower impairment in daily activities with male sex (OR 0.59, 95% CI 0.43--0.80), analgesics (OR 2.75, 95% CI 1.88--4.03) and depression (OR 1.14, 95% CI 1.07--1.21). The housing situation showed significant less impairment in daily activities for participants living in a care home (OR 0.51, 95% CI 0.28--0.93) and more impairment for participants living at home with care support (OR 1.72, 95% CI 1.08--2.74). For BMI stronger impairment in daily activities was significantly associated with overweight participants (OR 1.37, 95% CI 1.01--1.86). Education and Barthel-Index did not reach statistical significance. Discussion {#Sec14} ========== This was one of a few existing studies focusing on the prevalence of pain and associated factors such as age, gender, use of analgesics, cognitive state, medication and depression among the population of 85+ year olds. Age {#Sec15} --- The study demonstrated a high prevalence of pain (63%) among the age group of 85+ and strong experience impairments with everyday life due to pain (69%). Additionally, our findings suggest that older adults report less pain. These findings are supported by Zyczkowska (2007) \[[@CR25]\] who reported decreasing pain scores with growing age for both men and women. The researchers name a changing, more accepting attitude towards pain with increasing age, a "survival bias" meaning only the healthiest managed to reach very old age as possible grounds for these results. In depth research could provide more distinct answers into what leads to these changes in old age and may help overcome fears of ageing. Gender {#Sec16} ------ Regardless of the cognitive state, men seem to experience less pain and impairment in everyday life due to pain. According to these findings, female gender could increase the risk of experiencing pain. Similar finding have been reported in literature across all age groups \[[@CR6], [@CR25], [@CR26]\]. Reasons can be differences in individual pain perception, personal coping strategies or social settings \[[@CR27], [@CR28]\]. Gaining a better understanding of the different kinds of pain may also play an important role and may allow deeper insight of coping strategies and physiological factors in men and women \[[@CR29], [@CR30]\]. Housing situation {#Sec17} ----------------- Regarding the housing situation, our data show differences for the housing arrangements chosen in late life. In our sample, 47.8% of women and 34.5% of men aged 90+ years are living in care homes where activities of daily living are reduced and support through care staff is given in many areas \[[@CR1]\] which may reduce possible pain hazards. Furthermore, it can be speculated that the availability and home visits of general practitioners are at a higher frequency than in any other housing setting which could have positive effects on pain management. It may also explain why on the other hand participants living at home receiving care experience significantly more pain and more impairment in activities of daily living. Health care services providing care in the community are generally under immense time pressure and restriction of duties applied by the indication of care level or previous health care assessments e.g. supplying medication, changing bandaging, wash the person. It is also unclear whether pain assessment is part of health care services in the community by default nor if caring relatives focus on the issue. Hence the differences in pain prevalence point to a gap in pain management in

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iw: חשיבה שמתאמת בין סוגי הטיפול במקום לפצל אותם. חשיבה המבוססת על האוכלוסיה ועל הקהילה, במקום על בית החולים והרופאים. וחשוב מכל, עלינו לנטוש את המודל הרפואי המסורתי ולעבור למודל שמתחשב בגורמים החברתיים שביסוד הבריאות. כיום אנו מבינים שבריאותה של אוכלוסיה נקבעת בראש ובראשונה ע"י גורמים שאינם הטיפול הרפואי, או בתי החולים ומשרדי הרופאים. למעשה, אלה קובעים רק 10% מבריאותה של הקהילה. יתר ה-90% הם גורמים התנהגותיים וחברתיים. מה כוונתי ב"גורמים חברתיים שקובעים את המצב הבריאותי"? כוונתי לגורמים כגון מצב חברתי-כלכלי, הזדמנויות השכלה, בטחון תעסוקתי ובטחון מקום העבודה, דיור, שכונות בטוחות, מעמד חברתי, ומה שבמיוחד חשוב בעיני: התחושה שיש לכם מקום בחברה, Spanish: Uno que coordine los cuidados, no uno que lo fragmente. Uno que se base en la comunidad y en la población, en vez de uno basado en el hospital y los médicos. Y, lo que es más importante, tenemos que cambiar el sistema de atención sanitaria tradicional por uno que haga frente a los factores sociales que repercuten en la salud. Y ahora entendemos que la salud de la población está determinada sobre todo por factores que son de asistencia médica, ni hospitalaria ni consultas médicas. De hecho, esto solo constituye el 10% de lo que determina la salud de una comunidad. El otro 90% depende de factores sociales y de comportamiento. Y, ¿a qué me refiero con factores sociales que repercuten en la salud? Me refiero a factores como el nivel socioeconómico, las oportunidades educativas, el puesto de trabajo y la seguridad laboral, la vivienda, los barrios seguros, el estatus social y uno que es especialmente importante para mí: sentir que tienen un lugar en la sociedad, Russian: Та, которая координирует лечение, а не разваливает его. Та, которая ориентирована на население и общество, а не на больницу и врача. И нам, самое главное, необходимо перейти с традиционной медицинской модели на модель, которая охватывает социальные факторы здоровья. Мы понимаем, что здоровье населения обусловлено преимущественно другими факторами, помимо лечебной работы, больниц и кабинетов врачей. В сущности, они составляют всего 10% того, что определяет здоровье общества. Остальные 90% — это поведенческие и социальные факторы. Что же я подразумеваю под социальными факторами здоровья? Я имею в виду такие факторы, как социально-экономический статус, возможности для получения образования, профессия и гарантия рабочего места, жильё, безопасные районы, социальный статус, и особенно важным для меня является осознание того, что ты являешься частью общества, Portuguese: Um que coordene a assistência à saúde, em vez de fragmentá-la. Um que tenha como base a população e a comunidade, em vez de hospitais e médicos. E nós, principalmente, precisamos abandonar o modelo médico tradicional por um modelo que adote as determinantes sociais de saúde. Hoje, entendemos que a saúde de uma população é predominantemente determinada por fatores alheios aos cuidados clínicos, a hospitais e a consultórios. Na verdade, eles somam apenas 10% do que determina a saúde de uma comunidade. Os outros 90% são fatores comportamentais e sociais. O que quero dizer por determinantes sociais de saúde? Quero dizer fatores como a situação socioeconômica, as oportunidades de educação, a segurança profissional e no trabalho, moradia, bairros seguros, status social e um que é especialmente importante para mim: a sensação de se ter um lugar na sociedade, Spanish: sentir que tienen un sistema de asistencia social, sentir que los valora. Y sabemos que aquellos que se sienten infravalorados sufren mala salud. Cuando estaba en acogida, vi a niños que no tenían la oportunidad de recibiruna educación y ahora sé que si no conseguían un título de secundaria, eran cinco veces más propensos a tener peor salud que yo, que tenía formación universitaria. Y vi a niños que solo habían vivido en la pobreza, y ahora sé que son ocho veces más propensos a tener mala salud que sus compañeros más afortunados. Mis experiencias me han mostrado la relación entre estos factores sociales sanitarios y el estado de salud de una comunidad y de una persona. Y estas realidades exigen que hagamos frente a los factores sociales que repercuten en la salud Y este es mi mensaje: la salud no es solo responsabilidad de los médicos. Japanese: あなたが社会的保証制度を得ていると感じていることそしてあなたが尊重されていると感じていることです私は尊重されていないと感じる人は不健康であることを知っています私が

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281, 253, 1786, 187, 7955, 2688, 15, 4325, 253, 1929, 2219, 285, 19749, 46321, 24835, 13, 309, 2797, 4209, 2739, 187, 20612, 2476, 29892, 326, 253, 40501, 22462, 369, 4518, 3636, 347, 253, 48615, 4958, 15, 187, 42, 840, 11580, 253, 10301, 13, 6730, 253, 9189, 13, 2797, 3081, 29892, 13, 285, 187, 49845, 1243, 37263 ]

you name it — to hand out souvenir token coins. Often, these tokens could be redeemed for special offers — like a free meal, free admission, or something like that. Even places like Chuck E. Cheese used to have tokens that you could use to play arcade games. Many of these old tokens are collectible and are worth $1 to $5. Rare tokens, such as those that were used during the Civil War era, are worth hundreds of dollars. Big Coins “I have a large Indian Head penny. Is it rare? What’s it worth?” I’ve gotten this specific question more than a few times over the years. I actually own one of these replica coins, and I bought it for $4 at an old-timey tourist gift shop in Florida. Large coins like this are neat-looking replicas, but that’s all they are. They’re not legal tender in any way. Most of these big coins are made from base metals and aren’t typically worth more than $3 to $5. Big coins come in many different designs. I’ve personally seen the following: Large Lincoln pennies Large Buffalo nickels Large Jefferson nickels Large Mercury dimes Large Roosevelt dimes Large Washington quarters Large Walking Liberty half dollars Large Franklin half dollars Large Kennedy half dollars Large Morgan silver dollars Large Peace silver dollars Large Eisenhower dollars While none of these big coins are rare or valuable, they make great conversation pieces and look cool on the mantle. Tiny Coins “I have a tiny Kennedy half dollar. What’s it worth?” On the opposite end of the spectrum are tiny coins that look like the real thing but are only a fraction of the size of their regular coin counterparts. In fact, they’re tiny novelty coins. Some of them were made for doll play sets. Some are play money. But those realistic-looking, mini coins that you may have are small novelty coins that are 100% true to the original coins they replicate — they’re just a fraction of the size! I bought a few of these tiny coins just for the fun of owning some. They’re worth 50 cents to $1 apiece, and while they’re not rare (and certainly aren’t legal tender), they’re still pretty awesome to hold in the hand. Two-Headed Coins (Or Coins With Two “Tails” Sides) “Why does my nickel have Jefferson on both sides? What’s this two-headed coin worth?” I always hate breaking the news to people that these coins aren’t valuable and, technically, they aren’t even legal tender. These two-headed (or double tails) coins are usually fantasy pieces that were made by hollowing out the side of one coin right up to the rim and meticulously (and snugly) fitting another coin inside the shell. Normally, two-headed coins are made for illusionists or people who want to win bar bets. Exonumia coins like this are worth anywhere from 25 cents to a few dollars as novelty coins. But they aren’t rare, and you don’t want to try spending any as real money! Coins That Are Blank On One Side However, modern minting techniques make it virtually impossible to strike a coin that looks perfect on one side and completely blank on the other. NOTE: There are some real error coins that look weak or somewhat mutilated on one side. Different types of error coins like this exist, and based on the origin of the error are worth between $5 and $100 (or more). Normally, when people ask me questions about coins that are blank on one side, the photo I end up seeing is a coin that looks normal on one side but has tiny grooves or striations on the “blank” side. That typically means somebody sanded away or sheared off the other side and later polished it to look like the coin was really struck only on one side. Blank coins are real coins that have been terribly mutilated to look like unusual one-sided coins. Often, they’re produced for illusionists or people fascinated with fantasy coins or other exonumia oddities. For the most part, these one-sided coins may be neat to look at, but have no monetary value in the general coin collector market. Colorized Coins “My American Silver Eagle is painted red, white, and blue. What’s it worth?” Colorized coins are real coins that have been altered outside of the U.S. Mint. Some private mints will colorize regular Washington quarters, American Silver Eagle coins, or other pieces and sell them as special novelty coins. While these painted coins are often beautiful works of coin art, they are not rare and aren’t valuable. In numismatic terms, colored coins are usually worth only whatever the intrinsic metal content of the coin itself is worth. Other Types Of Strange Coins I’m a roller coaster junkie, a weather enthusiast, a frequent traveler, and a numismatist. My love for coins began when I was 11 years old. I primarily collect and study U.S. coins produced during the 20th century. I’m a member of the American Numismatic Association (ANA) and the Numismatic Literary Guild (NLG). I’ve also been studying meteorology and watching weather patterns for years. I enjoy sharing little-known facts and fun stuff about coins, weather, travel, health, food, and living green… on a budget. MORE LIKE THIS ... FREE U.S. COINS NEWSLETTER VIA EMAIL Stay up to date with what's happening on The U.S. Coin Guide. From finding Rare Coins to determining Coin Values and other Fun Things To Do With Coins... you'll always be the first to see these helpful tips as soon as we publish a new article.Search Results ENGL 201. English Literature to 1800. 3 Hours. A study of works representative of the major writers and periods from the Middle Ages through the 18th century, with emphasis on critical understanding of these works and on the influences that produced them. Prerequisite: (ENGL 101 with a minimum grade of D or HUM 101 with a minimum grade of D) and ENGL 102 with a minimum grade of D.A considerable number of food poisoning incidents occur every year in every major community. Such incidents often go unrecognized; and many recognized incidents are not reported to the health authorities. But occasionally the nature of the illness is so distinctive, the latent interval sufficiently short, and the numbers of people involved and the circumstances are such that a number of victims report their illnesses to the health department. These are the visible part of the food poisoning "iceberg", and it is imperative that all such reports be carefully received and recorded on a standard Food Poisoning Report form, by the epidemiologist, a designated public health nurse or sanitarian. Each report should then be promptly examined by the community epidemiologist, and whenever the nature and circumstances of the reported illness warrants it, an appropriate investigation must be quickly performed, initially by telephone. Often an investigation is triggered by a cluster of two or more reports closely associated in nature, time, and place. Herewith a number of food poisoning investigation reports from my files, which may be useful for neophyte epidemiologists when confronted with similar incidents: Occasionally we received bogus reports of food-borne illness; some from obvious cranks, or persons seeking to develop a basis for suing a restaurant or manufacturer; which wasted the time of one or more of us. And not infrequently, someone would bring a can or bottle with dubious contents and demand that we analyze the contents "for any poisonous substance". To do such an open-ended examination for every conceivable poison that might be in a specimen would require exorbitant expenditure of laboratory and manpower resources. But if we summarily refused to examine any such specimen, the offended party might soon complain about our disinterest to political officials, with repercussions. Hence, we ordinarily accepted such specimens, to be held in a refrigerator or freezer pending submission of one or more stool specimens, By requiring submission of a designated number of stool specimens before undertaking any extensive laboratory examination requested, we fended off many cranks few of whom are willing to go to the trouble of submitting multiple stool specimens. During my seven years with the Seattle-King County Health Department, I investigated many food poisoning outbreaks, some of which were quite memorable; and for some of which I have found reports. One such I remember, but for which I do not yet find a report, was from "The Maison Blanche" restaurant (no longer operative). It came to my notice because a number of prominent business persons who ate lunch there became sufficiently ill with high fever and diarrheal illness that they were hospitalized, and Salmonella Typhimurium isolated from their feces. These cases were reported to the health department. From the known cases and luncheon companions, I obtained sufficient food consumption histories that the crab salad was clearly identified as the offending vehicle. I then visited the restaurant, examined the facilities, obtained additional histories, and obtained rectal

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776, 3114, 13, 627, 403, 247, 2257, 273, 952, 751, 479, 835, 2622, 6498, 3038, 816, 1053, 457, 85, 789, 1425, 187, 187, 1989, 5909, 253, 11008, 3548, 457, 85, 253, 990, 14, 455, 273, 521, 5827, 15, 401, 483, 91, 310, 2819 ]

ila of the Road Runner and Coyote because the cliffs surrounding the cala are a deep orange similar to the cartoon! Cala Xarraca, Cala Tarida, Cala Xuclar and all the little rock pools around Figueretes and are some of the favourites. We hear Ibiza has several markets held weekly on the island. Any favourites? There are so many markets; I wish I had made it to more! There is a massive 'Hippy Market' in Punta Arabi, which is definitely worth a visit. You could spend the whole day there, as it's so big. They have live music and children's workshops so it's a great day out for the family. Friends of ours married on Formentera recently and had such a relaxing trip with their entire tribe. Do you guys go there? Formentera is paradise! We have only been once but we would love to go back and spend more time there. Fomentera is only a half-hour ferry ride from Ibiza so definitely a must-do while you are there, even if only for a day! We also love Mallorca, which is the larger island north of Ibiza. Weather-wise, when is the best time of year to visit Ibiza? We have always been in the summer so we can escape the Australian 'winter' but I would love to go in their winter. The locals say it has such a cool vibe and is so different to the tourist-packed summer. I really noticed this year how busy Ibiza was getting each day we were there so if you do go in summer, just be prepared for crowds. August is the busiest so I really enjoy June and September there as it's still warm but not crazy busy. Where do you usually stay and can you recommend any family-friendly areas? We have always stayed in the south-west of the island around Playa d'en Bossa, Figueretes and Talamanca. We prefer this area as it's close to the Old Town of Eivissa and not as touristy as it is around San Antonio on the other side of the island. Playa d'en Bossa is a main party area so can get a little crazy at night but I always felt fine having Lila there during the day and early evening. There are certainly more chilled parts of the island if you would prefer to be away from the action. I'd recommend hiring a car, as it’s the best way to see the island. Nothing is too far, and we would jump in the car and just go exploring. Everywhere is well signposted so we never used a GPS, which I loved as it reminded me of the old days. Anything else you wish to share about your travels that likeminded families may love to read? My biggest tip for travelling to Spain with children is to go with the flow! It's such a different lifestyle to ours in Australia and if you get caught up with staying in what may be a typical home routine, you might miss out on some of the fun! Lila is a night owl anyway but in Spain, she would go to bed late and sleep in late and we found that fit in better with Ibiza life. The sun doesn't set until 9.30ish in summer so the evenings are lovely to enjoy at the beach or outdoors. We enjoyed so many sunsets together which was really special. Also encourage your children to try the local foods and learn the language. It's amazing how adventurous they can be and what knowledge they take in.NEW DELHI -- India and France have joined hands to spearhead a global "solar revolution" with an aim to generate one terawatt of energy by 2030, an ambitious goal that requires $1 trillion in funds. "There are financial and regulation hurdles and capacity hurdles," said visiting French President Emmanuel Macron at the founding conference of the International Solar Alliance here on Sunday. He added the private and public sectors and society needed to come together to overcome these challenges. Indian Prime Minister Narendra Modi is the chief architect of the ISA that he launched with then French President Francois Hollande in Paris in November 2015 during a convention on climate change. The alliance involves 121 prospective member-countries that fall between the Tropics of Cancer and Capricorn, and are exposed to the "maximum solar intensity of over 300 days a year," acording to a bureaucrat at the Indian external affairs ministry. The ISA aims to facilitate the large-scale deployment of solar energy in those countries, that are home to 73% of the world's population -- by aggregating the demand for funding, technology and innovation. Indian Prime Minister Narendra Modi and French President Emmanuel Macron with other participants at the first conference of the International Solar Alliance in New Delhi on March 11. (Photo courtesy of Press Information Bureau of India) So far, 62 countries have signed the ISA framework agreement, out of which 32 have already ratified it. Australia, Bangladesh, Cuba, France, Ghana, India, Papua New Guinea, Sudan, Sri Lanka, Togo, the United Arab Emirates and Venezuela are among those that have ratified the agreement. These nations, Macron said, have 138 gigawatt of solar power potential over the next five years. "Depending on the countries, 20-50% of population does not have access to electricity," he said, pointing to the pent-up demand. During the summit, New Delhi also announced 27 solar projects under the Indian government's credit lines in 15 countries, including Bangladesh, Chad, Congo, Ghana, Mali, Rwanda and Sri Lanka. The estimated cost of these projects is $1.4 billion. Separately, Macron and Modi on Monday inaugurated a 100-megawatt solar power plant built by French firm ENGIE in northern Uttar Pradesh state's Mirzapur area, a key step in meeting the target of 100 gigawatt of electricity in India from solar energy by 2022. Macron applauded India's efforts in expanding renewable energy capacity within two years, from 39GW to 63GW, with solar energy growing up by 140%. "You [India] attracted investment, you supported them, you are training your own people. This is what the alliance of 121 countries in Africa, Asia, Latin America and Oceania shall be doing," Macron said Sunday. France, Macron said, has already met its 2015 pledge of providing 300 million euros ($369 million) to ISA member countries, and the French development agency will allocate an additional 700 million euros to its solar energy commitments by 2022. Referring to "solar mamas," a group of African women trained as solar engineers under an Indian government program, Macron said these women "didn't wait and didn't stop because some countries decided to just leave the floor and leave the Paris agreement." They kept on moving "because they decided it's good for them, their children and grandchildren. They decided to act and keep acting," he said. Macron's comment was an oblique reference to U.S. President Donald Trump's decision to withdraw from the Paris climate agreement reached in 2015 with an aim to curb global carbon emissions and slow rising temperatures. For his part, Modi pointed out that India has started the world's largest renewable energy expansion program. "We will generate 175GW of electricity from renewables by 2022, of which 100GW of power will be from solar energy." For the ISA, he presented an action plan that includes affordable solar technology for all, low-risk finance and an increased ratio of solar power in the energy mix. "We have to ensure that a better and affordable solar technology is easily accessible to everyone," he said. "We will have to provide concessional and low-risk financing for solar projects, and develop regulatory aspects and standards to [find solutions]," he said, adding consultancy support would be required for "bankable solar projects" in developing countries. Macron's 4-day India visit concludes on Monday.New Gym in Avon Opens for Business The new Raise the Bar fitness center and gym is officially open in Avon. Photo by Joy Crist The new Raise the Bar fitness center and gym in Avon is open for business, although an official grand opening as well as 24/7 hours of operation is on the horizon, per owner Seth Foutz. Foutz, a 20+ year chef and island resident, was one of the local members affected by the closure of the Spa Koru gym at the end of 2018, but after a little mentoring from Spa Koru owner Joe Thompson, he quickly set a plan in motion to open a new gym less than a half mile away from the former one. Raise the Bar is located at the Kinnakeet Corner complex at the edge of Avon Village, and the 2,700 square foot space features high-impact floors, new walls, and a variety of equipment throughout the spacious interior. Currently, the gym is open from 8 a.m. until 8 p.m., but Foutz will soon be installing a 24-hour keyless access system that will allow members to work out on their own schedule. “Working in the restaurant industry, I never went to gym in the summer because the hours [of operation] didn’t work with my schedule,” said Foutz in an earlier interview. “And in our community, there are a lot of people like me where normal operating hours just don’t work.” But opening the doors isn’t the end-all of his plans. Foutz is looking

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497, 2264, 7891, 313, 10387, 13440, 13, 14215, 2798, 2728, 285, 34879, 26954, 7891, 558, 2264, 13440, 21055, 285, 7891, 313, 12554, 272, 5678, 14215, 2798, 2728, 285, 34879, 26954, 21055, 285, 7891, 558, 285, 18185, 1955, 281, 10021, 3394, 15, 12979, 6933, 7587, 313, 1348, 13, 26881, 5705, 2239, 16, 30, 3925 ]

, and then the drop down option "My Vouchers." Here you will see all the deals you have purchased. If you purchased a voucher from us, it will show up there as "2712 Designs". Click on the blue button "View Voucher", which will give you a download of your voucher code and instructions on how to redeem under "How to Use." Your Groupon voucher will begin with "G" and end with either "REC" , "SQ", "EMB" or "HND" depending on the item that you purchased. Not sure where you should be? Check the end of your voucher code: If your voucher code ends in REC, your voucher is valid on a rectangle stamp design which can be found here: Rectangle Stamps If your voucher code ends in SQ, your voucher is valid on a square stamp stamp design which can be found here: Square Stamps If your voucher code ends in EMB, your voucher is valid on a desk embosser stamp design which can be found here: Desk Embossers If your voucher code ends in HND, your voucher is valid on a hand embosser stamp design which can be found here: Hand Embossers Still having difficulty? 1. Make sure to click on the product link provided with your voucher to ensure you are taken to the correct product page associated with your voucher code (also see above). 2. Be sure that you copy and paste your voucher code from the purchaser and paste it into the coupon box in the checkout page. Voucher codes must be exact, missing or having just one character off will cause your voucher to be rejected. 3. Check that your voucher has not expired. Expired vouchers can be used as store credit for the paid value. Please contact for assistance if your voucher has expired. How do I redeem my voucher?Choose the stamp design that you would like under Shop > Self-Inking Stamps or Self-Inking Square Stampsand click "Order." Fill in personalization lines. Double check all spelling & punctuation and then click "Add to Cart." Repeat process if you would like to order additional stamps or click on the cart icon on the top right corner to continue to checkout. Type or paste in voucher code in the white box and then click "Apply Coupon." Once voucher code had been deducted, click on "Proceed to Checkout." Enter your billing, shipping address and payment information to complete your order. My Voucher code is not working? Please note that all of our voucher codes end with the following letters: REC - Codes ending in this will only work with rectangle stamps found here SQ - Codes ending in this will only work with square stamps found here Will I get a digital proof of my stamp? No, unfortunately a digital proof is not included in this deal. When will my stamp ship? After you have placed your order and redeemed your voucher through the 2712 Designs website, your stamp order will ship within 10-14 business days. When your order has shipped an email confirmation including tracking number will be sent to the email used to place your order through 2712 Designs. You can track your order here ---> Track My OrderI purchased more than one voucher, but it's only letting me enter one voucher? If you've purchased more than one voucher, you will need to make a separate order for each voucher code. I placed my stamp order, but would like to make a change? Once your order has been submitted we may be able to make a change as long as it has not been made. Please email us and we can assist you with this. Locating your voucher code: After you place your order with LivingSocial, they provide you with a voucher code, which you then take to our website to redeem for a stamp. Your Living Social voucher will begin with "S" and end with either "REC" , "SQ" or "EMB" depending on the item that you purchased. To view your voucher code: Sign into your LivingSocial account, click on your username at the top right hand corner, and then the drop down option "My Vouchers." Here you will see all the deals you have purchased. If you purchased a voucher from us, it will show up there as "2712 Designs". Your LivingSocial voucher will begin with "S" and end with either "REC" , "SQ", "EMB" or "HND" depending on the item that you purchased. Not sure where you should be? Check the end of your voucher code: If your voucher code ends in REC, your voucher is valid on a rectangle stamp design which can be found here: Rectangle Stamps If your voucher code ends in SQ, your voucher is valid on a square stamp stamp design which can be found here: Square Stamps If your voucher code ends in EMB, your voucher is valid on a desk embosser stamp design which can be found here: Desk Embossers If your voucher code ends in HND, your voucher is valid on a hand embosser stamp design which can be found here: Hand Embossers Still having difficulty? 1. Make sure to click on the product link provided with your voucher to ensure you are taken to the correct product page associated with your voucher code (also see above). 2. Be sure that you copy and paste your voucher code from the purchaser and paste it into the coupon box in the checkout page. Voucher codes must be exact, missing or having just one character off will cause your voucher to be rejected. 3. Check that your voucher has not expired. Expired vouchers can be used as store credit for the paid value. Please contact for assistance if your voucher has expired. Expired vouchers can be used as store credit for the paid value. Please click help on the right of the page. Please provide us with the following information: 1. Your voucher code 2. The email address you would like the store credit to be sent to Shipping fees vary by product. You can always see how much the shipping fees will be by adding what you want to the cart. Then click on the shipping calculator and the shipping fees will appear. We test all stamps functionality and quality before they are shipped, so I've included some helpful tips to ensure the best stamped image. First, I suggest removing and re-inserting your design plate as, although rare, it may have shifted while in transit. Please view the link included with a quick video on how to properly remove and insert your design plate. https://www.2712designs.com/how-to/ Here are our recommendations to get the best impression: 1. Use your stamp on a clean, dry, flat, hard surface such as a desk or non textured table. If you seem to be having difficulties with certain areas of your stamp, try stamping on a slightly cushioned surface such as an even stack of paper or a mouse pad. 2. Be sure that the item you are stamping is separate from the stack. Stamp on one layer at a time. 3. When using our stamps on enveloped, stamp before stuffing. When stamping on the flap, fold out and stamp on single surface. 4. Stamp in a clean, straight motion with even pressure. Keep the stamp body steady and do not rock as this may result in an uneven impression and unwanted ink marks. 6. While we do not recommend stamping on textured surfaces, it can be done but will most likely result in an uneven impression. 7. Our stamps are not suitable for use on glossy surfaces as the ink is water based and will not dry entirely. A speciality ink set can be purchased for glossy surfaced materials. Current processing is 10-14 business days. Rush Processing is available for an additional $30.00. Rush Processing gets your item made and shipped in 1 business day and includes USPS Priority Mail shipping (approx. 3-5 business day delivery time after shipment). If you would like this option, please select RUSH at checkout.Pharmacotherapy for hypertension in the elderly. Elevated blood pressure (known as hypertension) increases with age, and most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than diastolic hypertension, and occurs more commonly in older people. It is important to know the benefits and harms of antihypertensive treatment of hypertension in this age group. To quantify antihypertensive drug effect on overall mortality, cardiovascular mortality and morbidity and withdrawal due to adverse effects in people 60 years and older with mild to moderate systolic or diastolic hypertension. Updated search of electronic database of EMBASE, CENTRAL, MEDLINE until Dec 2008; previous search of two Japanese databases (1973-1995) and WHO-ISH Collaboration register (August 1997); references from reviews, trials and previously published meta-analyses; and experts. Randomized controlled trials of at least one year duration in hypertensive elders (at least 60 years old) comparing antihypertensive drug therapy with placebo or no treatment and providing morbidity and mortality data. Outcomes assessed were total mortality (including cardiovascular, coronary heart disease and cerebrovascular mortality); total cardiovascular morbidity and mortality (representing combined coronary heart disease and cerebrovascular morbidity and mortality); and withdrawal due to adverse events. Fifteen trials (24,055 subjects >/= 60

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take the BSD sockets API for granted, it wasn't obvious it was the right API. STREAMS were a competing API design on System V Revision 3. With the BSD Sockets API came the select() syscall. But why was it necessary? I always thought that the "proper" Unix way to write network servers in was to create one worker process for each connection. In case of TCP/IP servers, this meant the accept-and-fork model: sd = bind (); while ( 1 ) { cd = accept ( sd ); if ( fork () == 0 ) { close ( sd ); // Worker code goes here. Do the work for `cd` socket. exit ( 0 ); } // Get back to `accept` loop. Don't leak the `cd`. close ( cd ); } While this model may be sufficient for writing basic network services 3, it's not enough for non-trivial programs. Terminal multiplexing Around 1983, Rob Pike was developing Blit, a fancy graphical terminal for Research Unix 8th Edition. Best to see it in action: Here's the Blit research paper for the curious. Blit clearly did terminal multiplexing. It allowed users to interact with multiple virtual consoles over a single physical serial link. I asked Mr. Pike about the history of select : Accept-and-fork, as you call it, makes it impossible for multiple clients to share state on the server. It's not just about networking either; one influence was the work with the Blit. While running two synchronous processes to power cu was sufficient, it wasn't enough to power Blit. Blit did require some kind of socket multiplexing facility to work smoothly. I would speculate that there was an theoretical alternative. One might try to extend the cu model and hack together a file descriptor multiplexer by spawning multiple processes blocking on I/O and having them synchronized on some kind of IPC. Unfortunately no decent IPC mechanisms existed for BSD. System V IPC was released in January 1983, but nothing comparable was implemented on BSD. I went through the 4.2BSD man pages and couldn't find any kind of real IPC4. With lack of any serious IPC mechanisms, it seems likely that Blit simply needed select to be able to do the console multiplexing. Back to sockets I contacted Kirk McKusick about the history of select . He replied: Select was introduced to allow applications to multiplex their I/O. Consider a simple application like a remote login. It has descriptors for reading from and writing to the terminal and a descriptor for the (bidirectional) socket. It needs to read from the terminal keyboard and write those characters to the socket. It also needs to read from the socket and write to the terminal. Reading from a descriptor that has nothing queued causes the application to block until data arrives. The application does not know whether to read from the terminal or the socket and if it guesses wrong will incorrectly block. So select was added to let it find out which descriptor had data ready to read. If neither, select blocks until data arrives on one descriptor and then awakens telling which descriptor has data to read. [...] Non-blocking was added at the same time as select. But using non-blocking when reading descriptors does not work well. Do you go into an infinite loop trying to read each of your input descriptors? If not, do you pause after each pass and if so for how long to remain responsive to input? Select is just far more efficient. Select also lets you create a single inetd daemon rather than having to have a separate daemon for every service. Here we are. Mr. McKusick confirms that non-blocking I/O simply didn't exist before select . Furthermore, he cites the cu terminal use case - it would be hard to write a telnet client without I/O multiplexing. Finally, he mentions inetd , which although introduced later in 4.3BSD, would have been impossible without select . Recap Having to run two processes to get cu working was a hack. With lack of any serious IPC it was impossible to emulate socket multiplexing in Blit without select . Furthermore select was needed to implement inetd . On architecture level select is needed to implement stateful servers which allow some state sharing between client connections. Here's another snippet from the "UNIX Time-Sharing System: A Retrospective" page 1966: [In UNIX] input and output ordinarily appear to be synchronous; programs wait until their I/O is completed. [...] There remain special applications in which one desires to initiate I/O on several streams and delay until the operation is complete on only one of them. When the number of streams is small, it is possible to simulate this usage with several processes. However, the writers of a UNIX ncp ("network control program") interface to the Arpanet feel that genuinely asynchronous I/O would improve their implementation significantly. Early Unix systems were pretty basic and select was simply not needed. It's not that blocking I/O model in C was deemed the best programming paradigm for everyone. This model made sense because all you could do were simple operations on files. This all was changed with the advent of network. Network application required things like inetd , stateful servers and terminal emulators like telnet . These things would be hard to implement had the OS not allowed socket multiplexing. Conclusion In this discussion I was afraid to phrase the core question. Were Unix processes intended to be CSP-style processes? Are file descriptors a CSP-derived "channels"? Is select equivalent to ALT statement? I think: no. Even if there are design similarities, they are accidental. The file-descriptor abstractions were developed well before the original CSP paper. It seems that an operating socket API's evolved totally disconnected from the userspace CSP-alike programming paradigms. It's a pity though. It would be interesting to see an operating system coherent with the programming paradigms of the user land programs. Let me leave you with a couple of vaguely related links: Ever wondered why select uses a bit mask to pass file descriptor list to kernel? Because 4.2BSD allowed only 20 file descriptors per program. uses a bit mask to pass file descriptor list to kernel? Because 4.2BSD allowed only 20 file descriptors per program. History of Actors programming model Channel I/O STREAMS and Solaris Guide and "A Stream Input-Output System" by Ritchie. mpx and mpxio or mpxcall - an early IPC / file desciptor multiplexing API. I think these were introduced in 1979 Version 7 Unix: "Multiplexed files: A feature that did not survive long was a second way (besides pipes) to do inter-process communication: multiplexed files. A process could create a special type of file with the mpx system call; other processes could then open this file to get a "channel", denoted by a file descriptor, which could be used to communicate with the process that created the multiplexed file. Mpx files were considered experimental, not enabled in the default kernel, and disappeared from later versions, which offered sockets (BSD) or CB UNIX's IPC facilities (System V) instead (although mpx files were still present in 4.1BSD)." Update: Mr. Pike clarified a bit of early history: Greg Chessons mpx was in v7 unix by the late 1970s, well before 1983 and BSD. Sockets were just one attempt in a crowded environment. The predecessor to the Blit used Greg's mpx. I think the very earliest Blit stuff did too, but by the time the movie was made v8 had happened and Dennis Ritchie gave me streams and select (but no sockets!). Select and sockets were roughly the same time but not necessarily two parts of one thing. The last statement is telling. select came at the same time as sockets, but it wasn't implemented purely for networking. It seems that all of multiplexing, sockets and IPC came at about the same time, without a coherent grand design. A number of people helped with this article: Rob Pike, Kirk McKusick, Ólafur Guðmundsson, Martin J. Levy, David Wragg and Tony Garnock-Jones. Thanks! Update: In a twitter exchange Clifford Heath noted that there was nonblocking I/O on TTY devices before 1983. There was nonblocking I/O before 1983. The University of Melbourne CS dept paused in 1980/1 to play Hack, and I used it for Pacman. I wonder how it worked. What ioctl's did it use and what were the semantics. Perhaps read() was nonblocking? Upate: Paul Ruizendaal followed up this blog post with some more investigation into early history. His findings are documented in The History of Unix mailing list: Continue reading about Select() being fundamentally broken →[2019/03/28] "Pretty Guardian Sailor Moon" The Super Liveを彩る楽曲たちの配信が決定しました！明日3月29日(金)より、iTunesとApple Musicの2サイトで、1曲ごとにダウンロード購入が可能となります。 ※全楽曲Instrumentalでの配信となります。さらに、ア

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the SMBH mass to grow at a rate given by ${\epsilon_{\rm heat}}c^2 {\dot M}_{\rm BH} = L_{\rm cool}$. We adopt values ${f_{\rm Edd}}= 0.01$ and ${\epsilon_{\rm heat}}=0.02$ for these parameters, based on @Fanidakis15. The results in this paper are not very sensitive to these values. (@Bower08 considered an alternative AGN feedback scheme in [<span style="font-variant:small-caps;">galform</span>]{}, in which energy input from AGN is able to expel most of the hot gas halo, rather than just balance radiative cooling. However, in this paper we retain the simpler @Bower06 AGN feedback scheme, in line with other [<span style="font-variant:small-caps;">galform</span>]{}papers.) Dynamical processes {#ssec:dynamics} ------------------- Galaxies evolve according to a variety of dynamical processes, as we now describe. ### Galaxy mergers We classify galaxies into [*central*]{} galaxies, which sit at the centres of their DM halos and can grow by accreting gas which cools in that halo, and [*satellite*]{} galaxies which orbit within the DM halo, and are assumed not to accrete any gas from the hot gas halo. When DM halos merge, we assume that the central galaxy in the most massive progenitor halo becomes the new central galaxy, while all other galaxies are left as satellites in the new halo. Satellite galaxies merge with the central galaxy in their host DM halo on a timescale set by [*dynamical friction*]{}. In @Cole00, we used a dynamical friction timescale which was calculated analytically from the Chandraskhar dynamical friction formula, but did not include the effects on the dynamical friction rate of tidal stripping of the DM subhalo hosting the satellite galaxy. In the new model, we replace this with a modified expression obtained by fitting to the results of cosmological N-body/hydrodynamical simulations of galaxy formation [@Jiang08; @Jiang10], which automatically incorporates the effects of this tidal stripping: $$\begin{aligned} \lefteqn{\tau_{\rm merge} = } \nonumber \\ & & \frac{f(\epsilon)}{2 C} \frac{M_{\rm pri}}{M_{\rm sat}} \, \frac{1}{\ln\left( 1 + M_{\rm pri}/M_{\rm sat} \right)} \, \left( \frac{{r_{\rm circ}}}{{r_{\rm vir}}} \right)^{1/2} \, \tau_{\rm dyn,halo} . \label{eq:taumerge}\end{aligned}$$ This gives the time for a satellite to merge with the central galaxy from when it falls in through the virial radius of the main halo, in terms of the masses $M_{\rm sat}$ of the satellite system (galaxy plus DM halo) and $M_{\rm pri}$ (galaxies plus DM halo) of the primary at infall, and [*circularity*]{} $\epsilon$ of the satellite orbit (at infall), defined as the ratio of the orbital angular momentum to that of a circular orbit of the same energy in the same potential, and ${r_{\rm circ}}$, the radius of this equivalent circular orbit. The constant $C=0.43$, while $f(\epsilon) = 0.90 \epsilon^{0.47} + 0.60$ is the fit found by @Jiang08. In applying this formula, we draw a random value of $\epsilon$ for each satellite from the probability distribution of orbital parameters of infalling satellite halos measured by @Benson05 from cosmological N-body simulations. The merger time is calculated when the satellite first falls into the main halo. If the satellite has not merged with the central galaxy by the time of the next halo mass doubling event, then the merger time is recalculated for the new halo, drawing a new value of $\epsilon$ from the distribution. [ (Note that, since we calculate the galaxy merger timescale analytically, rather than using the orbit of the satellite galaxy subhalo measured from the N-body simulation used in constructing the halo merger trees, our galaxy merger timescales are not affected by galaxies becoming “orphaned”, i.e. losing their subhalos due to effects of limited numerical resolution.)]{} The result of a galaxy merger depends on the ratio of baryonic mass (including both stars and cold gas) of the satellite, $M_{\rm b,sat}$, to that of the central galaxy, $M_{\rm b,cen}$. We define two different thresholds, ${f_{\rm burst}}\leq {f_{\rm ellip}}\leq 1$. (a) Mergers with $M_{\rm b,sat}/M_{\rm b,cen} > {f_{\rm ellip}}$ are classed as [*major*]{}. We assume that any stellar disks are destroyed and transformed into a stellar spheroid, while all of the cold gas collapses into the newly formed spheroid. Other mergers are classed as [*minor*]{}. In minor mergers, stars from the satellite are added to the spheroid of the central galaxy, but the cold gas is added to the disk of the central galaxy, without changing the specific angular momentum of the latter. (b) Mergers with $M_{\rm b,sat}/M_{\rm b,cen} > {f_{\rm burst}}$ (which includes all major mergers) trigger starbursts, in which all of the cold gas from the merging galaxies is transferred to the spheroid and then consumed by star formation or ejected by the resulting SN feedback. Numerical simulations of galaxy mergers imply ${f_{\rm ellip}}\sim 0.3$ and ${f_{\rm burst}}\sim 0.1$ [e.g. @Mihos94; @Barnes98; @Hopkins09]. We treat ${f_{\rm ellip}}$ and ${f_{\rm burst}}$ as adjustable parameters, but only in small ranges around these values. ### Disk instabilities Galaxies can also undergo morphological transformations and trigger starbursts due to disk instabilities. Galaxy disks which are dominated by rotational motions are unstable to bar formation when they are sufficently self-gravitating. Based on the work of @Efstathiou82, we assume that disks are dynamically unstable to bar formation if $${F_{\rm disk}}\equiv \frac{{V_{\rm c}}({r_{\rm disk}})}{\left( 1.68 \, G{M_{\rm disk}}/{r_{\rm disk}}\right)^{1/2}} <{F_{\rm stab}}, \label{eq:disk_stability}$$ where ${M_{\rm disk}}$ is the total disk mass (stars plus gas), ${r_{\rm disk}}$ is the disk half-mass radius, and the factor $1.68$ relates this to the disk exponential scalelength.[^9] The quantity ${F_{\rm disk}}$ measures the contribution of disk self-gravity to its circular velocity, with larger values corresponding to less self-gravity and so greater disk stability.[^10] @Efstathiou82 found a stability threshold ${F_{\rm stab}}\approx 1.1$ for a family of exponential stellar disk models, while @Christodoulou95 found ${F_{\rm stab}}\approx 0.9$ for a family of gaseous disks. We treat ${F_{\rm stab}}$ as an adjustable parameter in the range $0.9 {\lesssim}{F_{\rm stab}}{\lesssim}1.1$, with larger values resulting in more disks becoming unstable. Note that a completely self-gravitating stellar disk would have ${F_{\rm disk}}=0.61$. If the disk satisfies the instability condition ${F_{\rm disk}}<{F_{\rm stab}}$ at any timestep, then we assume that the disk forms a bar, [ which then thickens due to vertical buckling instabilities and evolves into a spheroid [@Combes90; @Debattista06]. We assume that this newly formed spheroid incorporates all of the stellar mass of the pre-existing disk and of any pre-existing spheroid. We also assume that bar formation triggers a starburst that consumes any cold gas present.]{} While in reality the timescale for growth of the bar and its evolution into a bulge is likely to be at least several disk dynamical times, in the model we approximate this whole process as happening instantaneously, as soon as the disk instability condition is met. Galaxy sizes {#ssec:sizes} ------------ Our model for galaxy sizes is identical to that in @Cole00. Galaxies consist of a disk and a spheroid embedded in a DM halo. These three components interact with each other gravitationally. (a) We assume that the disk has an exponential surface density profile, with a half-mass radius ${r_{\rm disk}}$ that is set by angular momentum conservation and by centrifugal equilibrium in the combined gravitational potential of disk, bulge and halo. When the disk accretes gas by cooling from the halo, it is assumed to gain angular momentum equal to that which this gas had in the halo before it cooled. When the disk loses gas through SN feedback, this is assumed to leave the specific angular momentum of the disk unchanged. Apart from this, the disk angular momentum remains constant, but the disk radius adiabatically adjusts in response to changes in the gravitational potential. (b) We assume that the spheroid is spherical and has an $r^{1/4}$ law surface density profile, with 3D half-mass radius ${r_{\rm bulge}}$. The initial size of the spheroid formed in a galaxy merger or disk instability is set by a combination of energy conservation and vir

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exp}$ by forcing a biomass dependent flux through a suited maintenance reaction, e.g., hydrolysis of ATP into ADP and phosphate. Note that the flux we need to force through maintenance strongly depends on how detailed the model is and how much lumping of reactions has been done. We therefore cannot provide an order of magnitude approximation for how much flux should be forced. Modelers should however be aware that the need for a large ATP maintenance forced flux to match experimental growth rates is an indication of model errors or poor model quality. Using a maintenance reaction makes sense also from a biological perspective, since one can usually not claim that the constructed resource allocation model covers all energy expending processes in an actual cell, so such an ATP maintenance reaction serves the purpose of modeling this remaining energy expenditure. 8. The SBML Representation of a Resource Allocation Model {#sec8-metabolites-07-00047} ========================================================= For metabolic network models used together with constraint-based modeling, it is standard to define them in the systems biology markup language (SBML), an XML-based way of representing models (<http://sbml.org/Main_Page>). However, there is so far no specific way of representing resource allocation models, which come with several extra ingredients in addition to the metabolic network part. Therefore, in this section we propose a way of making use of the existing SBML capabilities for representing resource allocation models \[[@B13-metabolites-07-00047]\]. We illustrate this proposal using a toy resource allocation model listed in [Table 3](#metabolites-07-00047-t003){ref-type="table"} for which we attach the SBML representation in the Supplement. 8.1. Compartments {#sec8dot1-metabolites-07-00047} ----------------- We keep any compartments present from the original reconstruction of the metabolic network. If possible, we place species objects for the additional gene products in the compartments in which the corresponding enzymes are acting. This means, e.g., that enzymes are located where the reactions they catalyze are happening. Species without any real physical location in the model, e.g., lumped species, can be placed arbitrarily in any compartment. Note that the compartments are not used in the formulation of the deFBA problem, besides the identification of external species. 8.2. Species {#sec8dot2-metabolites-07-00047} ------------ As postulated by the SBML standard, each `species` object must contain the attributes: `id``compartment``constant (true or false)``boundaryCondition (true or false)``hasOnlySubstanceUnits (true or false)``initialAmount` All species in the model also contain a `ram:species` annotation. We distinguish between limiting extracellular metabolites, for which the amount changes by cellular uptake (as N${}_{1}$ and N${}_{2}$ in the toy model), nonlimiting extracellular metabolites, where the amount is assumed to be unchanged by cellular uptake (as O${}_{2}$ in the toy model), intracellular metabolites (N, AA, ATP), storage (Stor), and biomass components (ETrans1, ETrans2, EMetab1, EMetab2, EStor, S, R). As per SBML specifications, a `boundaryCondition` value of `true` means a differential equation derived from the reaction definitions should not be generated for the species. Thus, in RAM, the nonlimiting extracellular species should have `boundaryCondition` = "`true`" as the amount of species at the systems boundary cannot be changed by the reactions, while all other species should have `boundaryCondition` = "`false`". The mandatory attribute `constant` is used in RAM, as per SBML definition, to specify whether a species amount is assumed to be changing or not in a deFBA simulation. With the deFBA approach this can only be `constant` = "`true`" for nonlimiting boundary species. Still, these species should only have `constant` = "`false`" if they are changed by extracellular processes such as oxygen through gas exchange. All other species will always have `constant` = "`false`". In order to generate the mathematical model for the deFBA problem in terms of molar amounts, each external, storage, and biomass species element must be assigned an initial value, either by setting the `initialAmount` attribute and `hasOnlySubstanceUnits` = "`true`", or by setting the `initialConcentration` attribute, `hasOnlySubstanceUnits` = "`false`", and specifying the `size` attribute of the respective compartment. Other mathematical models may require less information, for example for RBA it would be sufficient to specify the amounts or concentrations of the external species. We show in [Table 4](#metabolites-07-00047-t004){ref-type="table"} examples on how to set the mandatory species fields for each metabolite type. In addition to the required SBML fields listed above, each species must have a RAM annotation `ram:speciesType` specifying its type. We distinguish between the species types "`extracellular`", which can be either limiting or nonlimiting extracellular species"`metabolite`", which are species that obey the quasi-steady-state approximation Constraint ([5](#FD5-metabolites-07-00047){ref-type="disp-formula"})"`storage`", which represent the storage species $\mathcal{C}$"`enzyme`", which represent species $\mathcal{P}$ with catalytic role involved in Constraint ([7](#FD7-metabolites-07-00047){ref-type="disp-formula"})"`quota`", which represent quota species $\mathcal{P}$ that are enforced using Constraint ([9](#FD9-metabolites-07-00047){ref-type="disp-formula"}) The biomass species have additionally an annotation field `ram:molecularWeight` for storing their molecular weight $w_{i}$, an annotation field `ram:objectiveWeight` for their objective weight $b_{i}$, and an annotation field `ram:biomassPercentage` for their the biomass percentage $\phi_{i}$. The `ram:biomassPercentage` attribute contains the fractions of the quota components ([8](#FD8-metabolites-07-00047){ref-type="disp-formula"}) that need to be enforced at each time point. Below we show the annotation fields for the ribosome and the structural component as examples. Ribosome R: <species id="R" name="Ribosome" compartment="cytosol" initialAmount="0.03364" constant="false" boundaryCondition="false" hasOnlySubstanceUnits="true"> <annotation> <ram:RAM xmlns:ram="https://www.fairdomhub.org/sops/304"> <ram:species ram:molecularWeight="weight_R" ram:objectiveWeight="weight_R" ram:biomassPercentage="zero" ram:speciesType="enzyme"/> </ram:RAM> </annotation> </species> Structural component S: <species id="S" name="Structural biomass component" compartment="cytosol" initialAmount="0.7499" constant="false" boundaryCondition="false" hasOnlySubstanceUnits="true"> <annotation> <ram:RAM xmlns:ram="https://www.fairdomhub.org/sops/304"> <ram:species ram:molecularWeight="weight_S" ram:objectiveWeight="weight_S" ram:biomassPercentage="bp_S" ram:speciesType="quota"/> </ram:RAM> </annotation> </species> Note that "`weight_R`", "`weight_S`", "`zero`", "`bp_S`" are `id`s of parameters defined in the list of parameters of the SBML model. ### 8.2.1. Guideline to Ensure Uniqueness of Macromolecule IDs {#sec8dot2dot1-metabolites-07-00047} There are some enzymes that can act in different compartments of the cell, cf. [Section 4.5](#sec4dot5-metabolites-07-00047){ref-type="sec"}. An example is fumarase, which catalyzes reactions both in the cytosol and in the mitochondrion in yeast. While we include the respective compartments for the species in their description, a potential error is to give both enzymes the same `id`, either in their `species` or their `fbc:geneAssociation` representation. Hence, we suggest to name enzymes in a specific pattern combining, e.g., their name and their respective location. If the enzyme is acting in only one compartment we choose its `id` in the format "Main_id\_\[acting-compartment\]". If the enzyme is a transporter between two compartments we choose "Main_id\_\[compartment1\]\_\[compartment2\]". If the enzyme is translated from only one gene (e.g., ETrans1), this represents the main `id`. For enzyme complexes made of multiple gene products we suggest simply using "E\[id(s) of catalyzed reactions\]" as main `id` (e.g., ETrans2). Of course, the user can choose these `id`s freely, but following these suggestions can help with easier evaluation

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will have suffered the most, given their infrastructures would be too weak to withstand the power of a category 5 cyclone," said Suva resident Alice Clements, a spokeswoman for UNICEF in the Pacific. "Families may have lost their homes and crops, therefore leaving them without shelter, food and a livelihood." Although not hit directly, the capital, Suva, endured damaging gale-force winds, heavy rain and power outages. Clements, who was in Suva when the storm struck, said the city experienced "destructive, howling winds, and the sound of rivets lifting from roofs a constant throughout the night." More than 1,200 people were in evacuation centers around the country, the disaster management ministry said. The Colonial War Memorial Hospital in Suva suffered extensive water damage, and the roof of a local hospital was blown off in the northwestern town of Ba, said Sune Gudnitz, head of the U.N. Office for the Coordination of Humanitarian Affairs regional office for the Pacific. Widespread flash flooding and coastal inundation -- flooding in normally dry land -- "is likely as storm surges may push the sea inland several hundred meters," the Red Cross said. The western city of Nadi, on Fiji's main island, suffered minor wind damage but experienced extensive flooding, CNN affiliate TVNZ reported Fiji, an archipelago collectively about the size of New Jersey, lies in the South Pacific Ocean some 1,800 miles from Australia's east coast. (By comparison, Hawaii is about 2,500 miles from Los Angeles.) Most of the nation's 900,000 residents live on one of two main islands: Viti Levu or Vanua Levu.Breuil-le-Vert Breuil-le-Vert is a commune in the Oise department in northern France Population See also Communes of the Oise department References INSEE Category:Communes of OiseNotícias em Português 24 members - Público - Observador - Diário Económico - RTP Notícias - Agência Lusa Admin: Notícias de Publicações Portuguesas:- Público- Observador- Diário Económico- RTP Notícias- Agência LusaAdmin: @tiaaaagoo If you have Telegram, you can view and join Notícias em Português right away.Please log in Register now for free First Name * Last Name * Email * A valid e-mail address. All e-mails from the system will be sent to this address. The e-mail address is not made public and will only be used if you wish to receive a new password or wish to receive certain news or notifications by e-mail. Rereading the Fossil Record: The Growth of Paleobiology as an Evolutionary Discipline Most palaeontologists now take it for granted that our subject has significant things to say about the nature of evolutionary change; uniquely, we have the time dimension. Yet the fossil record is undeniably incomplete, and until quite recently, a prevailing view - among population geneticists, for example - was that palaeontologists had little to offer. As the evolutionary biologist John Maynard Smith put it, they should "go away and find another fossil, and not bother the grown-ups". Not so many biologists hold such views now. There is a good reason for it, almost entirely due to the labours of a small but exceptionally vigorous group of US palaeontologists for some 15 years during the 1970s and 1980s. The whole concept of palaeontology changed dramatically, and a separate discipline, palaeobiology, was born, with its own journal: Paleobiology. Palaeontology may, or may not, have a seat at the "high table" of evolutionary biology (if there is such a thing). But this group did an extraordinary job of trying to get there. This splendid book tells a fascinating tale; here we find the gentlemanly Norman Newell, the young tigers Niles Eldredge and Stephen Jay Gould, the brilliant, prickly Tom Schopf, the innovative David Raup, the late Jack Sepkoski (father of the author), Steven Stanley, James Valentine and many other extraordinary personalities. We read of their insights, interactions, disagreements, quarrels, personal lives and contributions. Sadly, not a few died before their time. The critical figure among them was the late Gould, but they all needed each other, despite quarrelling. So what were the basic concepts of palaeobiology? Effectively, it made palaeontology less descriptive and more theoretical, invoked computer modelling and quantitative analysis of the fossil record, brought in biological evolutionary concepts and emphasised the evolutionary implications of the fossil record. None of this would have been possible without new technology; namely, modern high-speed computers. A critical question was whether the patterns of change seen in the fossil record are real. Eldredge and Gould proposed "punctuated equilibria" in 1972 - in other words, rather than even and slow transformation of populations, there was rapid origin of new types, in small populations, followed by longer periods of stasis. On the other hand, Schopf was convinced that most evolutionary change was stochastic - largely random, uninfluenced by external causes. His computer-generated "spindle" models closely matched patterns seen in nature, and he never abandoned this idea. Gould, meanwhile, believed (rightly in my view) in determinism by natural selection. Raup generated computer models of coiled mollusc shells, of which only a fraction of possible forms are used in nature. Extinctions came to be seen as highly important drivers of evolution, resetting the scenario each time. By the 1980s, five major mass extinctions had been recognised, with causes identified. Jack Sepkoski's ideas of three successive "evolutionary faunas", originating, evolving and becoming extinct together, gained wide acceptance. So did Stanley's concept that evolution above the species level was decoupled from species selection. Other ideas, such as a 26-million-year periodicity in extinctions, flourished briefly before dying. Our perspective on the fossil record and its value for evolution changed immensely as a result of this work. Palaeontology is now much more biological, although still firmly rooted in the fossil record. We recognise that evolution is hierarchical, with genes, organisms, populations, species and genera representing different levels, and these are (or may be) operating independently. The new synthesis is not anti-Darwinian, as has been claimed. Rather, to quote David Sepkoski: "Modern evolution theory is remarkable for the continuing validity of Darwin's original insights, and also for its adaptability." That is the take-home message, and it is absolutely true. Rereading the Fossil Record: The Growth of Paleobiology as an Evolutionary Discipline5. Partitioning with fdisk This section shows you how to actually partition your hard drive with the fdisk utility. Linux allows only 4 primary partitions. You can have a much larger number of logical partitions by sub-dividing one of the primary partitions. Only one of the primary partitions can be sub-divided. Examples: Four primary partitions (see Section 5.2) Mixed primary and logical partitions (see Section 5.3) 5.1. fdisk usage fdisk is started by typing (as root) fdisk device at the command prompt. device might be something like /dev/hda or /dev/sda (see Section 2.1.1). The basic fdisk commands you need are: p print the partition table n create a new partition d delete a partition q quit without saving changes w write the new partition table and exit Changes you make to the partition table do not take effect until you issue the write (w) command. Here is a sample partition table: Disk /dev/hdb: 64 heads, 63 sectors, 621 cylinders Units = cylinders of 4032 * 512 bytes Device Boot Start End Blocks Id System /dev/hdb1 * 1 184 370912+ 83 Linux /dev/hdb2 185 368 370944 83 Linux /dev/hdb3 369 552 370944 83 Linux /dev/hdb4 553 621 139104 82 Linux swap The first line shows the geometry of your hard drive. It may not be physically accurate, but you can accept it as though it were. The hard drive in this example is made of 32 double-sided platters with one head on each side (probably not true). Each platter has 621 concentric tracks. A 3-dimensional track (the same track on all disks) is called a cylinder. Each track is divided into 63 sectors. Each sector contains 512 bytes of data. Therefore the block size in the partition table is 64 heads * 63 sectors * 512 bytes er...divided by 1024. (See The first line shows the geometry of your hard drive. It may not be physically accurate, but you can accept it as though it were. The hard drive in this example is made of 32 double-sided platters with one head on each side (probably not true). Each platter has 621 concentric tracks. A 3-dimensional track (the same track on all disks) is called a cylinder. Each track is divided into 63 sectors. Each sector contains 512 bytes of data. Therefore the block size in the partition table is 64 heads * 63 sectors * 512

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Lithuania and King of Poland Sigismund II Augustus and his mother queen Bona Sforza were spending much of their time in the Royal Palace of Lithuania. The Polonization of Vilnius proceeded through the influx of Polish elements and assimilation of non-Polish burghers. It started in the late 14th century with the arrival of Polish clergy, followed by artisans and merchants; they migrated in larger numbers after the Polish court of Sigismund August moved to the city. Polish-Lithuanian Commonwealth After the Union of Lublin (1569) that created the Polish–Lithuanian Commonwealth, the city flourished further in part due to the establishment of Vilnius University by Stephen Báthory, King of Poland and Grand Duke of Lithuania in 1579. The university soon developed into one of the most important scientific and cultural centers of the region and the most notable scientific center of the Grand Duchy of Lithuania. Political, economic and social life was in full swing there. This is among all proven by the Lithuanian Statutes issued in the 16th century, the last of which was still in force until the 19th century. In 1610 the city was racked by a large fire. In 1769 the Rasos Cemetery was founded; today it is one of the oldest surviving cemeteries in the city. Rapidly developing, the city was open to migrants from both East and West. In addition to old citizens, larger Jewish, Orthodox and German communities established themselves in the city. Each group made its contribution to the life of the city, and crafts, trade and science prospered. In the 17th century, Polish and polonized elements achieved a cultural and likely numerical preponderance. In 1655 during the Russo-Polish War in 1654–1667 Vilnius was captured by the forces of Tsardom of Russia and was pillaged, burned and the population was massacred. The death toll of around 20,000 included a large proportion of Vilnius Jews. The city's growth lost its momentum for many years, yet the number of inhabitants recovered. During the decline of the Commonwealth, Vilnius became known as "Jerusalem of the North" - a major religio-cultural center of Eastern European Jewry. Russian Empire After the Third Partition of Polish-Lithuanian Commonwealth in 1795, Vilnius was annexed by the Russian Empire and became the capital of Vilna Governorate, a part of the Northwestern Krai. In order to allow the city to expand, between 1799–1805 period, the city walls were pulled down, only the Dawn Gate (also known as Aušros vartai, Medininkų vartai or Ostra Brama, Вострая Брама) remained. In 1803 Alexander I re-established the Polish-language University. In 1812 the city was seized by Napoleon on his push towards Moscow. After the failure of the campaign, the Grande Armée retreated to the area where 80,000 of French soldiers died and were buried in the trenches they had built months earlier. After the November Uprising the Vilnius University was closed and repressions halted the further development of the city. Civil unrest in 1861 was suppressed by the Imperial Russian Army. During the January Uprising in 1863 heavy city fights occurred, but were brutally pacified by Mikhail Muravyov, nicknamed The Hanger by the population because of the number of executions he organized. After the uprising, Polish language was banned from public use. The Latin alphabet was prohibited in 1859 (Belarusian language) and in 1865 (Lithuanian language) - the ban was lifted in 1904. During the second half of 19th and the beginning of 20th century Vilnius also became one of the centers of Jewish, Polish, Lithuanian and Belarusian national rebirths. According to the 1897 Russian census, by mother tongue, 40% of the population was Jewish, 31% Polish, 20% Russian, 4.2% Belarusian and 2.1% Lithuanian. Jewish culture and population was so dominant that some Jewish national revival leaders argued for a new Jewish state to be founded in a Vilnius region, with a city as its capital. These national revivals happened in Vilnius because it was one of the most tolerant, progressive and liberal places in a region, legacy of the tolerance deriving from the years of the Grand Duchy of Lithuania. One of the most important Polish, Belarusian poets and writers published their works in Vilnius at that time. It was the place where the first short-lived Belarusian weekly Naša Niva was founded. Vilnius became an important place of act of the Lithuanian national revival on 4–5 December 1905, when the Great Seimas of Vilnius was held in the Palace of the present-day National Philharmonics, with over 2000 delegates from all regions of Lithuania as well as emigrees. It was decided to make a demand to establish an autonomous ethnic Lithuanian state within the Russian Empire with its parliament (Seimas) in Vilnius. Cultural life was revived after the 1905 Russian Revolution. Society of Friends of Science in Wilno was created in 1906 in order to practice science and literature in Polish language. The Emilia and Eustachy Wróblewski Library, the center of Polish culture, was established in 1912, around that time also Polish theater was revived. Polish cultural life was still repressed despite its revival. In 1907 bishop Eduard von der Ropp was expelled from Vilnius to Vitebsk. Interwar period Polish-Lithuanian conflict During World War I, Vilnius was occupied by Germany from 1915 until 1918. Still under German occupation, Council of Lithuania proclaimed the Act of Independence of Lithuania in Vilnius on 16 February 1918. Act proclaimed restoration of the independent state of Lithuania with Vilnius as its capital. The German civilian administration of the Ober-Ost declined to pass full authority to Lithuania, which was not controlled by the Germans any more. Instead, the Germans tried to control the area by means of promoting conflicts between local nationalities as it became clear that the German plan for creation of Mitteleuropa, a net of satellite buffer states, failed. Finally, on 1 January 1919, the German garrison withdrew and passed the authority over the city to a local Polish committee, against the pleas of the Lithuanian administration. A Polish administration started to be formed. Former members of the local Polish Self-Defence formations, now formally enlisted into the Polish Army, took over the posts while the Lithuanians withdrew along with the Germans. On 5 January 1919 the city was taken by Bolshevik forces advancing from the east. Vilnius was proclaimed the capital of the Lithuanian–Byelorussian Soviet Socialist Republic. For the next 4 months the city became a communist experiment in governance. During the course of that conflict, on 19 April 1919 the city was again seized by Poland (Vilna offensive), this time by forces of the regular Polish Army. A year later, on 14 July 1920, it was lost to Soviet forces again (this time, the Soviets were aided by Lithuanians, who were promised Vilnius). Shortly after the defeat in the Battle of Warsaw in 1920, the withdrawing Red Army handed the city over to Lithuania, in accordance with the Soviet–Lithuanian Peace Treaty of 12 July 1920. The treaty allowed for the transfer to Lithuanian authority of some part of the areas of the former Grand Duchy of Lithuania. Although the city itself, as well as its surroundings were actually transferred, the fast pace of the Polish offensive prevented additional territories to be handed over by the Red Army and the disputed area was split into Lithuanian and Polish-controlled parts. Many historians argue that the main reason behind the Soviet agreement with Lithuania was to weaken Poland and hand the disputed territories to a weaker state, which Lithuania was at the time, in order to reconquer the area more easily after the retreat of the Red Army had halted. Also, the independence of the Baltic States was seen by Lenin as temporary. However, after the Battle of the Niemen River the Red Army was again defeated and Bolshevik Russia was forced to abandon her plans for reincorporation of all the lands lost by the Russian Empire in the Treaty of Brest-Litovsk. As Russia ceased to be a major player in the area, Polish-Lithuanian relations worsened. In demographic terms Vilnius was one of the most Polonized and Russified of Lithuanian cities during 1795-1914 Russian rule, with Lithuanians constituting a mere fraction of the total population: 2% - 2,6% according to Russian (1897), German (1916) and Polish (1919) censuses. The latter two indicated that 50,1% or 56,2% of the inhabitants were Poles, while the Jewish share in the population amounted to 43,5% or 36,1% (they were conducted after large part of the inhabitants of Vilnius were evacuated to Russia, mostly Voronezh because of war in 1915). The Lithuanians nonetheless have strong historical claim to the city (former capital of the Grand Duchy of Lithuania, the very center of the formation of medieval Lithuanian state) and refused to recognize any Polish claims to the city and the surrounding area. Lithuanian national activists, for example: Mykolas Biržiška and Petras Klimas, supposed Poles and Belarusians in the Vilnius province to be "Slavicized Lithuanians" who, regardless of their individual preferences,

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ої потреби спецпідрозділів (так званих "маски-шоу") на обшуках; слідчий матиме право це робити лише у випадках загрози для життя чи здоров’я учасників слідчих дій і тільки на підставі ухвали слідчого судді. Нарешті, парламент поклав край ходінню співробітників різних правоохоронних органів по черзі на одне і те ж саме підприємство за одним і тим самим фактом "можливого порушення" законодавства. Йдеться про ситуації, коли спочатку приходить запит від СБУ чи поліції, а через кілька місяців за цим самим фактом в двері стукає прокуратура з ухвалою слідчого судді, бо інформація передається "між своїми" по колу. Тепер закон не дозволяє правоохоронним органам проводити розслідування і навіть зобов’язує закрити кримінальне провадження, якщо є не скасована постанова слідчого про закриття кримінального провадження щодо того ж діяння, яке вже розслідувалось з дотриманням вимог по підслідності. Законопроект №7275 є беззаперечним першим кроком вперед на шляху захисту підприємств та їх службових осіб від свавілля з боку правоохоронців, але дотримання його положень буде значною мірою залежати від того, хто та як його виконуватиме. Поки наші правоохоронні органи залишаються фактично не реформованими, я маю певний скепсис, що ухвалений закон запрацює на корить бізнесу. Тому, уряду варто бути послідовним та зробити другий, більш важливий крок: створити фінансову поліцію та ліквідувати економічні підрозділи прокуратури, нацполіції та податкову міліцію, а також оперативні "економічні" підрозділи СБУ. Якщо ми боремося за підприємця та інвестиційний клімат, то повинні нарешті створити один дієвий орган, який буде розслідувати злочини проти публічних фінансів держави. Третій рік фінансова поліція, на заміну податкової міліції та іншим "економічним" підрозділам, лише обговорюється. Депутатський законопроект майже два роки не ставили на голосування і не розглядали в Раді. Мінфін його переробив на догоду силовикам в бік погіршення, однак, навіть у такому, спотвореному, вигляді, так і не спромігся зареєструвати в Раді. В грудні цього року відбудеться Національна рада реформ з цього питання та анонсоване внесення президентом нового законопроекту — про Бюро фінансової безпеки. Для мене не принципово, як називатиметься новий орган. Натомість, важливо, щоб новий орган з самого початку його створення не був політично залежним і не став кишеньковим "військом" для когось з можновладців для зведення рахунків з політичними опонентами, конкурентами тощо. Це має бути новий центральний орган виконавчої влади, окремий від ДФС, від МВС, від будь-яких інших органів: - сформований на конкурсній основі, за аналогією з НАБУ, який не втручається в роботу бізнесу до встановлення факту злочину; - з посиленою аналітичною, а не силовою функцією; - з обмеженням для колишніх силовиків на роботу в ньому; - орган, який буде розслідувати всі злочини проти публічних фінансів держави, органів місцевого самоврядування, зловживань із міжнародною допомогою та кредитами. Але найголовніше — це те, щоб нова фінансова поліція була незалежною від політичних впливів, в тому числі і від президента, уряду, окремих політиків і виконувала просту функцію: карати тих, хто ухиляється від сплати податків, а не тих, хто наповнює бюджет. Тільки політична незалежність нового органу та чесний конкурсний добір керівництва, детективів, аналітиків забезпечать належний результат: чесний бізнес зможе спокійно займатися своєю господарською діяльністю, а не відбиватись чи відкупатись від

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TPFanControl under Windows or thinkfan under Linux. PSA testing without clinical indication for prostate cancer in relation to socio-demographic and clinical characteristics in the Danish Diet, Cancer and Health Study. Social differences in prostate cancer (PC) incidence and mortality might be related to testing for prostate-specific antigen (PSA). Although routine PSA screening is not recommended in Denmark, testing without clinical indication increased during the past decade. We evaluated associations between socio-demographic or clinical characteristics and PSA testing without clinical indication. In the Danish Diet, Cancer and Health Cohort, we identified 1051 men with PC diagnosed in 1993-2008. Diagnostic and clinical characteristics were obtained from medical records, and socio-demographic information was retrieved from administrative registers. We used general logistic regression analysis to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between socio-demographic or clinical characteristics and PSA testing without clinical indication. Cox regression analysis was used to examine associations with mortality. PSA testing without clinical indication was less likely among patients > 67 years (OR 0.7; 0.5-1.0). Men who were, PSA tested without clinical indication, were more likely to have vocational training (OR 1.8; 1.1-2.9) or higher education (OR 1.5; 0.9-2.5) and less likely to have advanced disease (OR 0.6; 0.4-0.9). PSA testing without clinical indication more often preceded therapy with curative intent (OR 1.8; 1.1-2.9) and less often palliative treatment (OR 0.6; 0.3-1.0). Men who were PSA tested without clinical indication had non-significantly lower overall and PC-specific mortality [hazard ratios 0.8 (0.5-1.2) and 0.6 (0.3-1.1), respectively]. PSA testing without clinical indication was associated with higher educational level. PC detected by PSA testing with no clinical indication was more often localized and treated with curative intent. From Lithuania, with Love (2018) - diodorus https://roadsandkingdoms.com/2018/from-lithuania-with-love/ ====== tasdomas What an interesting glimpse at a period that lives on the edge of my consciousness. I was 3 at that time, but I remember going to rallies with my parents a few years later. I also remember tanks and APCs parked all over Vilnius after the events of January 13th, 1991. The amount of respect, gratitude and admiration I feel for the people who drove the independence movement forward is difficult to describe. And then, every once in a while I meet somebody from Russia or some other post-soviet state and hear them longing for those "long gone days" or ask me "is it really that much better for you now?". It is. Much better. Sure, we have problems. Social and economical ones. But at least they are our problems. And we have the freedom to solve them on our own. ~~~ Fins It is certainly much better. And much nicer to visit than back then. ------ dTal I'm surprised at the lack of mention of the human chain, which is the most famous act of protest on the 23 August: "Approximately two million people joined their hands to form a human chain spanning 675.5 kilometres (419.7 mi) across the three Baltic states – Estonia, Latvia, and Lithuania, which were considered at the time to be constituent republics of the Soviet Union." A stark contrast with the article, which says "Only a few hundred people showed up". [https://en.wikipedia.org/wiki/Baltic_Way](https://en.wikipedia.org/wiki/Baltic_Way) ~~~ tasdomas The Baltic way was in 1989, two years after the first demonstration - maybe that's why the article did not mention it. Regardless, that too was a spectacular thing to do. ~~~ dTal Ah, my mistake. Still, a surprising omission, as the seminal anti-Soviet protest in Lithuania, and within the author's memory. module Vale.Stdcalls.X64.AesHash open FStar.HyperStack.ST module B = LowStar.Buffer module HS = FStar.HyperStack open FStar.Mul module DV = LowStar.BufferView.Down module UV = LowStar.BufferView.Up open Vale.Def.Types_s open Vale.Interop.Base module IX64 = Vale.Interop.X64 module VSig = Vale.AsLowStar.ValeSig module LSig = Vale.AsLowStar.LowStarSig module ME = Vale.X64.Memory module V = Vale.X64.Decls module IA = Vale.Interop.Assumptions module W = Vale.AsLowStar.Wrapper open Vale.X64.MemoryAdapters module VS = Vale.X64.State module MS = Vale.X64.Machine_s open Vale.AES.AES_s module GF = Vale.AES.X64.GF128_Init let uint64 = UInt64.t (* A little utility to trigger normalization in types *) noextract let as_t (#a:Type) (x:normal a) : a = x noextract let as_normal_t (#a:Type) (x:a) : normal a = x [@__reduce__] noextract let b128 = buf_t TUInt8 TUInt128 [@__reduce__] noextract let t128_mod = TD_Buffer TUInt8 TUInt128 default_bq [@__reduce__] noextract let t128_no_mod = TD_Buffer TUInt8 TUInt128 ({modified=false; strict_disjointness=false; taint=MS.Secret}) [@__reduce__] noextract let dom: IX64.arity_ok_stdcall td = let y = [t128_no_mod; t128_mod] in assert_norm (List.length y = 2); y (* Need to rearrange the order of arguments *) [@__reduce__] noextract let key128_pre : (Ghost.erased (Seq.seq nat32)) -> VSig.vale_pre dom = fun (s:Ghost.erased (Seq.seq nat32)) (c:V.va_code) (input_b:b128) (output_b:b128) (va_s0:V.va_state) -> GF.va_req_Keyhash_init c va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as_vale_buffer output_b) [@__reduce__] noextract let key128_post : (Ghost.erased (Seq.seq nat32)) -> VSig.vale_post dom = fun (s:Ghost.erased (Seq.seq nat32)) (c:V.va_code) (input_b:b128) (output_b:b128) (va_s0:V.va_state) (va_s1:V.va_state) (f:V.va_fuel) -> GF.va_ens_Keyhash_init c va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as_vale_buffer output_b) va_s1 f #set-options "--z3rlimit 20" [@__reduce__] noextract let key128_lemma' (s:Ghost.erased (Seq.seq nat32)) (code:V.va_code) (_win:bool) (input_b:b128) (output_b:b128) (va_s0:V.va_state) : Ghost (V.va_state & V.va_fuel) (requires key128_pre s code input_b output_b va_s0) (ensures (fun (va_s1, f) -> V.eval_code code va_s0 f va_s1 /\ VSig.vale_calling_conventions_stdcall va_s0 va_s1 /\ key128_post s code input_b output_b va_s0 va_s1 f /\ ME.buffer_writeable (as_vale_buffer input_b) /\ ME.buffer_writeable (as_vale_buffer output_b) )) = let va_s1, f = GF.va_lemma_Keyhash_init code va_s0 IA.win AES_128 (Ghost.reveal s) (as_vale_buffer input_b) (as

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The specific challenge is to balance... the state's interest in protecting the granddaughter's constitutional rights under the First Amendment of the United States Constitution to visit her grandparents ... and ... the parents' constitutional rights under the Fourteenth Amendment of the United States Constitution to control [the granddaughter's] life." Continuing, the grandparents assert that Code §§ 20-124.2 and 16.1-241 require that a court balance the interests of the state and the interests of the parents; that the circuit court has appropriately balanced the rights of all parties and found by clear and convincing evidence that their granddaughter's best interests would be served by requiring her to have limited visitation with her grandparents; and that the challenged statute is constitutional. Responding, the parents contend that Code § 20-124.2(B), as applied to them, is unconstitutional because the statute infringes upon their Fourteenth Amendment rights to conduct their family affairs free from governmental intrusion. B. The Fourteenth Amendment of the United States Constitution provides in relevant part that "[n]o state shall ... deprive any person of life, liberty, or property, without due process of law...." U.S. Const. amend. XIV, § 1. The United States Supreme Court, explaining the protections accorded by the Fourteenth Amendment, has stated: "While this Court has not attempted to define with exactness the liberty thus guaranteed, the term has received much consideration and some of the included things have been definitely stated. Without doubt, it denotes not merely freedom from bodily restraint but also the right of the individual to contract, to engage in any of the common occupations of life, to acquire useful knowledge, to marry, establish a home and bring up children, to worship God according to the dictates of his own conscience, and generally to enjoy those privileges long recognized at common law as essential to the orderly pursuit of happiness by free men." Meyer v. Nebraska, *422 262 U.S. 390, 399 [43 S.Ct. 625, 67 L.Ed. 1042] (1923). The Supreme Court observed in Moore v. East Cleveland, 431 U.S. 494, 499, 97 S.Ct. 1932, 52 L.Ed.2d 531 (1977), that it "has long recognized that freedom of personal choice in matters of marriage and family life is one of the liberties protected by the Due Process Clause of the Fourteenth Amendment" (quoting Cleveland Bd. of Educ. v. LaFleur, 414 U.S. 632, 639-40, 94 S.Ct. 791, 39 L.Ed.2d 52 (1974)). Additionally, the United States Supreme Court has stated its "historical recognition that freedom of personal choice in matters of family life is a fundamental liberty interest protected by the Fourteenth Amendment," Santosky v. Kramer, 455 U.S. 745, 753, 102 S.Ct. 1388, 71 L.Ed.2d 599 (1982), and that there is "a `private realm of family life which the state cannot enter.'" Moore, 431 U.S. at 499, 97 S.Ct. 1932 (quoting Prince v. Massachusetts, 321 U.S. 158, 166, 64 S.Ct. 438, 88 L.Ed. 645 (1944)). Accord Lassiter v. Department of Soc. Servs., 452 U.S. 18, 27, 101 S.Ct. 2153, 68 L.Ed.2d 640 (1981). The Supreme Court of the United States has made clear that a state may interfere with a parent's right to raise children only when the state acts in its police power to protect the health or safety of the child. See Wisconsin v. Yoder, 406 U.S. 205, 230, 92 S.Ct. 1526, 32 L.Ed.2d 15 (1972) (Amish children would not be harmed by receiving an Amish education instead of attending public high school); Prince, 321 U.S. at 170, 64 S.Ct. 438 (Supreme Court approved conviction of a guardian who allowed a child to sell religious magazines, finding a legitimate state interest in preventing psychological or physical injury to the child); Pierce v. Society of Sisters, 268 U.S. 510, 534, 45 S.Ct. 571, 69 L.Ed. 1070 (1925) (parents' decisions to send their children to private schools was not inherently harmful to children). Here, I am concerned with the parents' fundamental rights to raise their child as they deem appropriate. Therefore, any statute which seeks to limit those rights can only be justified by a compelling state interest, and such statute must be narrowly drawn to express only the legitimate state interest at stake. Washington v. Glucksberg, ___ U.S. ___, ___, 117 S.Ct. 2258, 2268, 138 L.Ed.2d 772 (1997); Reno v. Flores, 507 U.S. 292, 301-02, 113 S.Ct. 1439, 123 L.Ed.2d 1 (1993). Thus, this Court must consider whether Code § 20-124.2(B), as applied in this case, requires a finding of a compelling state interest before a court can interfere with the parents' fundamental rights to raise their child by awarding visitation to the grandparents over the parents' objections. VI. A. The language contained in Code § 20-124.2(B) is clear and unambiguous and, therefore, I would look no further than the plain meaning of the language contained in the statute to ascertain its meaning. Supinger v. Stakes, 255 Va. ___, 205-206, 495 S.E.2d 813, 817; City of Winchester v. American Woodmark Corp., 250 Va. 451, 457, 464 S.E.2d 148, 152 (1995). This Court has stated: "`While in the construction of statutes the constant endeavor of the courts is to ascertain and give effect to the intention of the legislature, that intention must be gathered from the words used, unless a literal construction would involve a manifest absurdity. Where the legislature has used words of a plain and definite import the courts cannot put upon them a construction which amounts to holding the legislature did not mean what it has actually expressed.'" Barr v. Town & Country Properties, Inc., 240 Va. 292, 295, 396 S.E.2d 672, 674 (1990) (quoting Watkins v. Hall, 161 Va. 924, 930, 172 S.E. 445, 447 (1934)); accord Supinger, 255 Va. at 206-07, 495 S.E.2d at 817-18; Haislip v. Southern Heritage Ins. Co., 254 Va. 265, 268-69, 492 S.E.2d 135, 137 (1997); Abbott v. Willey, 253 Va. 88, 91, 479 S.E.2d 528, 530 (1997); Weinberg v. Given, 252 Va. 221, 225-26, 476 S.E.2d 502, 504 (1996). B. In making visitation determinations, a juvenile and domestic relations district court must comply with the statutes contained in *423 Title 20, Chapter 6.1 of the Code, which is entitled, "Custody and Visitation Arrangements for Minor Children."[2] This chapter contains numerous statutes which relate to custody and visitation. Code § 20-124.1, which is contained in Chapter 6.1, makes clear that grandparents and certain other non-parents, are deemed to have a statutory interest in child visitation.[3] Code § 20-124.2 is entitled "Court-Ordered Custody and Visitation Arrangements." Code § 20-124.2(B) authorizes a court to award visitation to a non-parent with a legitimate interest. Code § 20-124.2(B) also establishes the standard that a court must apply when making a visitation determination. The court's determination must be based upon a showing by clear and convincing evidence that the best interests of the child would be served by an award of visitation. Code § 20-124.3, which establishes the factors that the court shall consider when applying the best interests of the child standard, states in part: "§ 20-124.3. Best interests of the child.In determining best interests of a child for purposes of determining ... visitation arrangements ... the court shall consider the following: "1. The age and physical and mental condition of the child, giving due consideration to the child's changing developmental needs; "2. The age and physical and mental condition of each parent; "3. The relationship existing between each parent and each child, giving due consideration to the positive involvement with the child's life, the ability to accurately assess and meet the emotional, intellectual and physical needs of the child; "4. The needs of the child, giving due consideration to other important relationships of the child, including but not limited to siblings, peers and extended family members; "5. The role which each parent has played and will play in the future, in the upbringing and care of the child; "6. The propensity of each parent to actively support the child's contact and relationship with the other parent, the relative willingness and demonstrated ability of each parent to maintain a close and continuing relationship with the child, and the ability of each parent to cooperate in matters affecting the child; "7. The reasonable preference of the child, if the court deems the child to be of reasonable intelligence, understanding, age and experience to express such a preference; "8. Any history of family abuse as that term is defined in § 16.1-228; and "9. Such other factors as the court deems necessary and proper to the determination." None of the

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Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ /* * Copyright (C) 2009-2020 Ping Identity Corporation * * This program is free software; you can redistribute it and/or modify * it under the terms of the GNU General Public License (GPLv2 only) * or the terms of the GNU Lesser General Public License (LGPLv2.1 only) * as published by the Free Software Foundation. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program; if not, see <http://www.gnu.org/licenses>. */ package com.unboundid.ldap.protocol; import java.io.ByteArrayInputStream; import org.testng.annotations.Test; import com.unboundid.asn1.ASN1Buffer; import com.unboundid.asn1.ASN1BufferSequence; import com.unboundid.asn1.ASN1Element; import com.unboundid.asn1.ASN1Integer; import com.unboundid.asn1.ASN1OctetString; import com.unboundid.asn1.ASN1Sequence; import com.unboundid.asn1.ASN1StreamReader; import com.unboundid.ldap.sdk.DN; import com.unboundid.ldap.sdk.GenericSASLBindRequest; import com.unboundid.ldap.sdk.LDAPException; import com.unboundid.ldap.sdk.LDAPSDKTestCase; import com.unboundid.ldap.sdk.ReadFromFilePasswordProvider; import com.unboundid.ldap.sdk.SimpleBindRequest; import com.unboundid.util.LDAPSDKUsageException; /** * This class provides a set of test cases for the {@code BindRequestProtocolOp} * class. */ public class BindRequestProtocolOpTestCase extends LDAPSDKTestCase { /** * Provides test coverage for the constructor which takes a string DN and a * string password. * * @throws Exception If an unexpected problem occurs. */ @Test() public void testBindRequestProtocolOpSimpleStringPassword() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp( "uid=test.user,ou=People,dc=example,dc=com", "password"); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), new DN("uid=test.user,ou=People,dc=example,dc=com")); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), "password"); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /** * Provides test coverage for the constructor which takes a string DN and a * binary password. * * @throws Exception If an unexpected problem occurs. */ @Test() public void testBindRequestProtocolOpSimpleBinaryPassword() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp( "uid=test.user,ou=People,dc=example,dc=com", "password".getBytes()); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op= BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), new DN("uid=test.user,ou=People,dc=example,dc=com")); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), "password"); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /** * Provides test coverage for the constructor which takes a string DN and a * string password with an anonymous bind. * * @throws Exception If an unexpected problem occurs. */ @Test() public void testBindRequestProtocolOpSimpleStringPasswordAnonymous() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp(null, (String) null); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), DN.NULL_DN); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), ""); assertNull(op.getSASLMechanism()); assertNull(op.getSASLCredentials()); assertEquals(op.getProtocolOpType(), (byte) 0x60); assertNotNull(op.toString()); } /** * Provides test coverage for the constructor which takes a string DN and a * binary password. * * @throws Exception If an unexpected problem occurs. */ @Test() public void testBindRequestProtocolOpSimpleBinaryPasswordAnonymous() throws Exception { BindRequestProtocolOp op = new BindRequestProtocolOp(null, (byte[]) null); ASN1Buffer buffer = new ASN1Buffer(); op.writeTo(buffer); byte[] opBytes = buffer.toByteArray(); ByteArrayInputStream inputStream = new ByteArrayInputStream(opBytes); ASN1StreamReader reader = new ASN1StreamReader(inputStream); op = new BindRequestProtocolOp(reader); op = BindRequestProtocolOp.decodeProtocolOp(op.encodeProtocolOp()); op = new BindRequestProtocolOp((SimpleBindRequest) op.toBindRequest()); assertEquals(op.getVersion(), 3); assertEquals(new DN(op.getBindDN()), DN.NULL_DN); assertEquals(op.getCredentialsType(), BindRequestProtocolOp.CRED_TYPE_SIMPLE); assertEquals(op.getSimplePassword().stringValue(), ""); assertNull(

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earthquake, when small lots of tract homes and row homes now characteristic of the neighborhood were built into the sand dunes. These tract homes would displace a smaller original settlement built into the dunes called Carville, which was so named for squatters that lived in abandoned horsecars (horse-drawn trolleys) and cable cars that were dumped in the sand dunes. Development increased by the 1930s, as the Sunset was built and developed into a streetcar suburb. The post–World War II baby boom in the 1950s saw the last of the sand dunes leveled down and replaced with more single- and multifamily homes. In these developments, built mostly by Henry Doelger, entire blocks consist mainly of houses of the same general character, differentiated by variations in their stucco facades and mirrored floorplans, with most built upon lots with no free space between houses. Later, Oliver Rousseau built more individualistic homes in the district. Historically, the Sunset's demographics were consisted mostly of European Americans, specifically Irish and Italian. Beginning in the late 1960s the neighborhood saw a steady influx of Asian (mostly Chinese) immigrants following the Immigration and Nationality Act of 1965 which lifted racial quotas allowing for more non-European nationals to immigrate to the United States. Additionally, the Handover of Hong Kong motivated many Chinese to immigrate to the U.S. due to the political and economic uncertainties. Today, the vast majority of the neighborhood's population is Asian, with Chinese as the dominant ethnic group. There are still some small Irish enclaves however. Sub-neighborhoods For most of its history, the Sunset existed as a large individual area. In recent years, the neighborhood has been popularly divided into three parts with sometimes vague borders. Inner Sunset The Inner Sunset is bordered by Lincoln Way to the north, 2nd Ave to the east, Quintara Street to the south, and 19th Avenue to the west. This far-east section of the Sunset is located just west of Mount Sutro. The main commercial area is along Irving Street from 5th Avenue to 12th Avenue, and along 9th Avenue from Lincoln Way to Judah Street, much of which is dotted with a variety of restaurants and shops. The Inner Sunset hosts a variety of local businesses, including restaurants, bars, breweries, book stores, bakeries, coffee shops, ice cream parlors, clothes and shoe stores, a tattoo parlor, and a wine bar. All these establishments are clustered around the intersection of 9th Avenue and Irving Street. Food offered by the restaurants located in the Inner Sunset includes pizza, Mexican, Thai, Persian, Korean, Malaysian, Hawaiian, Greek, Ethiopian, Pakistani, Cajun/Creole, Dim Sum, Turkish, Peruvian, Chinese, Vietnamese, California Cuisine, Mediterranean, Indian, Japanese, Vegetarian. Central Sunset The Central Sunset is bounded by Lincoln Way to the north, 19th Avenue to the east, Quintara Street to the south, and Sunset Boulevard to the west. This area is mostly residential with cookie-cutter homes and large lots and a commercial strip along Irving Street from 19th Avenue to 24th Avenue and on Noriega Street from 19th Avenue to 27th Avenue and 30th Avenue to 33rd Avenue. Features of the area include the massive Sunset Reservoir (which takes up eight square blocks between Ortega and Quintara streets and 24th and 28th avenues), which has a small park surrounding its outer rim; Golden Gate Park; the Sunset Recreation Center; and Abraham Lincoln High School. Outer Sunset The Outer Sunset is bordered by Lincoln Way to the north, Sunset Boulevard (between 36th and 37th avenues) to the east, Sloat Boulevard to the south, and Ocean Beach to the west. The primary commercial avenues are Judah, Noriega, and Taraval. The Outer Sunset is the foggiest section in San Francisco due to its close proximity to Ocean Beach. The area's main attractions include the San Francisco Zoo, Golden Gate Park, Ocean Beach, and Lake Merced. Attractions and characteristics The western part of the Sunset borders the cold northern California Pacific Ocean coastline, so it tends to get much of the fog San Francisco is famous for. The Sunset can be foggy and chilly for some days during summer. The Sunset's finest weather is usually from August through December, when regional air patterns transition from onshore to offshore weather and the area is free of fog. Sand carried by Pacific Ocean winds can be found on roadways and driveways within the first five to ten blocks east of Ocean Beach. The Sunset District contains several large park and recreation areas. The San Francisco Zoo is located in the southwestern corner of the neighborhood by Lake Merced, the largest lake within San Francisco. Also within the Lake Merced area are several golf courses: the private Olympic Club and San Francisco Golf Club, and the public TPC Harding Park. Across from Lake Merced is Fort Funston, an old coastal battery, now part of the Golden Gate National Recreation Area. Fort Funston notably has some of the last remnants of the sand dune ecosystem that once covered the entire Sunset District. There is a year-round, Sunday morning farmers' market which is located at 1315 8th Avenue (the parking lot between 8th and 9th Avenues). The market is operated by the Pacific Coast Farmers' Market Association and is sponsored by the Inner Sunset Park Neighbors. The Inner Sunset Farmers' Market offers California-grown produce, fish, eggs, and meat, as well as local food vendors and artisans. Stern Grove, a heavily wooded park and amphitheater located on Sloat Boulevard between 19th and 34th avenues, is known for its annual summer festival. Three parks lie on the far east border of the district: the northernmost is Grand View Park (also referred to as Turtle Hill) a small, elevated park surrounded by 14th and 15th Avenues, as well as Noriega Street; moving south, next is Golden Gate Heights Park, just east of 14th Avenue north of Quintara; and Hawk Hill Park, also east of 14th Avenue at Santiago. These natural areas belong to a remnant ridge-top system and include some of the last-remaining sand-dune communities in the city. Education The San Francisco Unified School District operates public K–12 schools. Educational institutions include the Parnassus campus and medical center of the University of California, San Francisco, located in Inner Sunset; the main campus of San Francisco State University, located in the southwestern corner of the neighborhood across from Lake Merced; Abraham Lincoln High School, located in the center of the Sunset District; St. Ignatius College Preparatory (a private, coeducational school operating in San Francisco since 1855) located since 1969 adjacent to Sunset Boulevard; and Lowell High School, the oldest public high school west of the Mississippi and one of the top performing ones in the United States. Beach culture The strip near the Pacific Ocean has a notable population of surfers who take advantage of the sometimes excellent surf conditions of Ocean Beach. Because of the cold Pacific current that brings ocean water from Alaska, it is usually necessary to wear a wetsuit when surfing at Ocean Beach. Several surf shops can be found near the beach in the Outer Sunset. Several playgrounds are located in the Sunset, including Sunset Playground and Recreation Center, Blue Boat Playground, West Sunset, McCoppin Square, and South Sunset. Current issues The current efforts to develop a comprehensive plan for this section of San Francisco is the Ocean Beach Master Plan (OBMP). The OBMP is an interagency effort to develop a long-term vision for Ocean Beach that will address numerous issues. Climate Like much of the coast of Northern California, Sunset district has a cool summer mediterranean climate, albeit with an unusual annual temperature distribution. The warmest days of the year occur in October and then the coldest nights of the year occur just two months later in December. Its climate is strongly influenced by the Pacific Ocean and therefore has even cooler summers and milder winters than downtown San Francisco. Rainfall follows a seasonal pattern with plentiful precipitation in the winter (almost all of this falling as rain) and extremely dry summers. References Further reading External links Articles related to the Sunset District at FoundSF.org http://outsidelands.org/sunset.php Information from the Western Neighborhoods Project Sunset Neighborhood Beacon Center, youth and family community center Category:Neighborhoods in San Francisco Category:History of San Francisco Category:Chinatowns in the United States Category:Chinese-American culture in San Francisco Category:Populated coastal places in CaliforniaBest answer chosen by InMotion Hosting staff Thanks for posting your question. I'm happy to assist you today. You don't have to worry about deleting a question. Simply log into the support center and mark the question as resolved. If you need further assistance please feel free to contact us.#!/usr/bin/make -f # Copyright (c) TurnKey GNU/Linux - http://www.turnkeylinux.org # # This file is part of Fab # # Fab is free software; you can redistribute it and/or modify it # under the terms of the GNU Affero General Public License as published by

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The facts as presented here are construed accordingly, and they are limited to this motion. I. Henderson's Early History at YAP Henderson was hired by YAP on May 14, 1990, as a Case Manager, by Pahigian with the approval of Weissman and O'Boyle. As one of the first three case managers hired to effectuate the Alternatives to Incarceration contract between the City and State of New York and what was then NCIA, Henderson was involved in establishing the duties and responsibilities of a case manager. Henderson's duties included supervision and management of approximately eight YAP clients. Specifically, his responsibilities included conducting intake and background investigations, developing alternative-to-detention plans to submit to the courts, advocating to the courts for the release of clients from detention into the Program, supporting the children and their families through direct community-based contact and interaction, and regularly submitting progress reports to the courts and other appropriate individuals. On April 11, 1991, Henderson received his first performance review. He received a grade of "outstanding", the highest available, in eight of the ten categories in which he was rated, one "high" grade, and one "normal" grade. Based upon this performance review, Henderson received a pay raise. In October 1991, Pahigian promoted Henderson to the position of Senior Case Manager, with an accompanying pay raise, and that promotion was approved by O'Boyle and Weissman. In addition to his case management duties, Henderson became responsible for assisting in the supervision of three case managers, including providing them with guidance in their casework with clients. On October 15, 1992, Henderson received another performance review. He received exclusively "outstanding" grades and received high praise. Indeed, throughout his tenure as Case Manager and Senior Case Manager, Defendants aver that Henderson was considered by Pahigian, O'Boyle, and Weissman to be an excellent and valued employee. In April 1993, Pahigian resigned, and, as part of YAP's restructuring, Henderson was promoted at the behest of Pahigian and with the efforts of Weissman and O'Boyle on July 1, 1993, to the newly created position of Director of Case Management Services ("DCMS"). As the first person to fill this new position, Henderson was involved in establishing the duties and responsibilities of the DCMS. His duties included direct supervisory responsibility and training of all case management staff, consisting of one Senior Case Manager and five case managers. Henderson had exclusive authority over case management decisions and bore responsibility for maintenance of all client files and records. Because of these additional supervisory responsibilities, Henderson carried a reduced caseload of four clients during his tenure as DCMS. Among his accomplishments during his tenure was to increase significantly the number of referrals to YAP, a goal in light of the fact that the Project had failed to meet its contractual goals during the previous fiscal year. Just before Henderson assumed the position of DCMS, following Pahigian's resignation in April, YAP operated until August 20, 1993, without a Project Director until Wong filled the vacancy. During this time, Henderson was the highest-ranking case management employee at YAP and had extensive latitude and autonomy. *695 II. The Automobile Incident Defendants allege that the relationship between Wong and Henderson began on poor footing, and that almost instantly upon taking over YAP, Wong experienced resistance from Henderson in accepting her supervision and authority. Their first exchange, besides mere pleasantries, consisted of an encounter in which Henderson objected to and challenged Wong's enforcement of a YAP policy on employee use of automobiles leased by the Project. Henderson asserts that the nature of this interaction was professional, not personally antagonistic. The details of the interaction are as follows. Case managers were allowed to use leased cars available to YAP as needed, provided use had been approved by either the Project Director or the Assistant Project Director. Because there was no Project Director at the time a memorandum was issued regarding this policy, Henderson, as DCMS, was allowed to approve the case managers' use of the cars. Several days after Wong began as Project Director at YAP, she issued a memorandum reiterating that only she or the Assistant Project Director could approve case managers' use of cars. Henderson's access to the cars remained unchanged, but he did confront Wong after learning of her memorandum, dismayed at the fact that she had made the change without first consulting with him. Defendants assert that this confrontation began a strained relationship between Henderson and Wong, marked by Henderson's refusal to adapt to Wong's different approach to management of YAP and to her tempering of his previous authority and control. Henderson states that the situation was relatively cordial once the misunderstanding had been worked out, and that there were no lingering bad feelings between him and Wong. III. The Crossroads Incident On October 15, 1993, Henderson overheard a Crossroads client, Simone, an African-American woman who was engaged in cleaning a bathroom at the YAP offices on the CCA premises, complaining that she had been compelled by the Crossroad program to do that work. Crossroads had only recently required its clients to clean the YAP bathrooms, and Simone informed Henderson of that fact. Also recently, Darrel, an African-American man, had been replaced as CCA's maintenance worker by John Clohessy ("Clohessy"), a white man. Henderson was dismayed upon learning of Crossroads' new policy. He asserts that there were two sources of his dismay. First, Henderson states, he believed that the practice of compelling Crossroads clients to clean CCA bathrooms was discriminatory and akin to slavery, because the Crossroads clients were exclusively black and Latino, because the new cleaning policy had been implemented at the same time that Clohessy had replaced Darrel, and because Clohessy had been hired to supervise the Crossroads clients, though Darrel had cleaned the CCA bathrooms without assistance. Second, Henderson states, he was bothered by the appearances presented by the Crossroads policy, believing them antithetical to the philosophy of CCA. Henderson asked Simone to stop cleaning the YAP bathrooms and advised her that he would speak to someone about the new requirement. When Bloomfield learned that day of Henderson's actions, he asked O'Boyle to call a meeting among the three of them. Bloomfield argued to O'Boyle that it was improper and potentially damaging from a treatment perspective for Henderson to undermine the authority of the Crossroads treatment team by giving any instructions directly to Crossroads clients. Bloomfield told O'Boyle that Henderson should have raised any concerns or objections with Bloomfield or another Crossroad employee. O'Boyle asked Henderson to come to her office, and Bloomfield reiterated his objections to Henderson's behavior. Henderson expressed his objection to the new cleaning policy as discriminatory, degrading to the clients, and contrary to the goals of CCA. Henderson further stated that he believed an improper appearance was presented by having the Crossroads clients cleaning, because of the stereotypes associated with that work, and in light of the fact that all of the Crossroads clients were all black or Latino. Bloomfield emphasized that all Crossroads *696 clients were required to undertake various responsibilities in order to instill a sense of ownership of the community as part of the Crossroads treatment program, and that this was a widespread therapeutic philosophy in other, similar treatment communities. Bloomfield stressed that the client responsibilities program had been instituted by Donna Harris, the Crossroads Director of Treatment, who is black. Henderson alleges that at the meeting, Bloomfield suggested that Henderson himself was a racist because Henderson had objected to the policy only because all of the Crossroads clients were members of minority groups and that Henderson would not have reacted to their cleaning the YAP bathrooms had they been white. Henderson also alleges that during the meeting, O'Boyle defended the policy in part because she claimed the Crossroads clients enjoyed cleaning. After the meeting, Crossroads no longer required its clients to clean the bathrooms on the YAP side of the CCA facility. Henderson states that this change in policy constituted a compromise to which O'Boyle and Bloomfield reluctantly agreed. Defendants state that they believed that Henderson had raised a valid point regarding the possibility of misinterpretation of the client responsibilities by those unfamiliar with the concept of rehabilitative treatment, and they thus decided to discontinue cleaning on the YAP side of the CCA facility, while continuing it on the Crossroads side. Subsequent to this meeting, Bloomfield and O'Boyle never discussed the issue again with Henderson. Defendants assert that neither Bloomfield nor O'Boyle discussed the incident with Wong prior to Henderson's discharge, believing the situation to be resolved. Henderson asserts that the incident became the focus of substantial discussion among Bloomfield, O'Boyle, Weissman, and the Crossroads staff over the next several weeks, and that his actions were cast in a negative light in the course of those discussions. IV. The File Review Because YAP contracts with the City of New York, the Project is subject to periodic site visits from City contractors monitoring YAP's compliance with the terms of the contract. The City monitors were scheduled to conduct a site visit of YAP on October 26, 1993. These site visits had occurred regularly during Pahigian's tenure as Project Director, but the October 26, 1993, visit was to be the first following Wong's employment as Project Director. Typically during these site visits, monitors conducted an audit of the case management files to assure that the clients were being adequately supervised upon release from detention in accordance with the contract terms. Defendants state that as the date for the monitors' visit neared, Henderson had not conducted a preliminary file inspection in preparation for the visit, and so Wong, growing anxious, conducted the inspection herself, with the assistance of O'Boyle. As they began to review the client files for each of the case managers, Wong

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get some basic Role management happening. When roles are used to enforce access restrictions within our application, they are basically hard-coded, usually via the [Authorize] attribute. Giving application administrators the ability to add, modify, and delete roles is of limited use if they cannot also modify the access permissions afforded by [Authorize] . The above notwithstanding, sometimes we might wish to add some properties to our basic roles, such as a brief description. In this post we will see how we can extend the IdentityRole class, by adding an additional property. We will also add the basic ability to create, edit, and delete roles, and what all is involved with that, despite the fact that any advantage to adding or removing roles is limited by the hard-coded [Authorize] permissions within our application. If you are using the Identity 2.0 Framework: This article focuses on customizing and modifying version 1.0 of the ASP.NET Identity framework. If you are using the recently released version 2.0, this code in this article won't work. For more information on working with Identity 2.0, see Many of the customizations implemented in this article are included "in the box" with the Identity Samples project. I discuss extending and customizing IdentityUser and IdentityRole in Identity 2.0 in a new article,ASP.NET Identity 2.0: Customizing Users and Roles If you are using the Identity 1.0 Framework: UPDATE: 2/24/2014 - Thanks to Code Project user Budoray for catching some typos in the code. The EditRoleViewModel and RoleViewModel classes were referenced incorrectly in a number of places, preventing the project from building properly. Fixed! We have laid the groundwork for what we will be doing in the previous article on Extending Identity Accounts, so we will clone that project and build on top of the work already done. In that project, we: Created a restricted, internal access MVC site. Removed extraneous code related to social media account log-ins, and other features we don't need. Extended the IdentityUser class to include some additional properties, such as first/last names, and email addresses. Added the ability to assign users to pre-defined roles which govern access to various functionality within our application. In the original project, I had left all of the Identity-related models in the single file created with the default project template. Before getting started here, I pulled each class out into its own code file. Also, we will be re-building our database and migrations. After cloning the source, I deleted the existing Migration (not the Migrations folder, just the Migration file within named 201311110510410_Init.cs. We will keep the Migrations/Configuration.cs file as we will be building out on that as we go. Previously, we were able to define the model class ApplicationUser, which extended the Identity class IdentityUser, run EF Migrations, and with relative ease swap it with IdentityUser in all the areas of our application which previously consumed IdentityUser. Things are not so simple, however, when it comes to extending IdentityRole. IdentityRole forms a core component in the authorization mechanism for an ASP.NET application. For this reason, we might expect the Identity system to be resistant to casual modification of the IdentityRole class itself, and perhaps equally importantly, the manner in which the rest of the identity system accepts derivatives. So we need to find a way to accomplish what we wish to achieve without compromising the integrity of the Identity mechanism, or those components downstream which may depend upon an instance of IdentityRole to get the job done. First off, let's take a look at our existing ApplicationDbContext class: The ApplicationDbContext Class: In the above, we can see we are inheriting from the class IdentityDbContext<TUser>, which allows us to specify a custom type, so long as that type is derived from IdentityUser. So it appears that the Identity system generally provides a built-in mechanism for extending IdentityUser. Is there a similar path for extending IdentityRole? Turns out there is. Sort of. As we can see, we have created a derived class and implemented a simple new Description property, along with a new overridden constructor. Next, we need modify our ApplicationDbContext so that, when we run EF Migrations, our database will reflect the proper modeling. Open the ApplicationDbContext class, and add the following override for the OnModelCreating method: Add These Namespaces to the Top of your Code File: using Microsoft.AspNet.Identity.EntityFramework; using Microsoft.AspNet.Identity; using System.ComponentModel.DataAnnotations; using System.Collections.Generic; using System.Data.Entity; using System; using System.Data.Entity.Infrastructure; using System.Data.Entity.ModelConfiguration; using System.Data.Entity.ModelConfiguration.Configuration; using System.Data.Entity.Validation; using System.Globalization; using System.Linq; using System.Linq.Expressions; using System.Reflection; using System.Runtime.CompilerServices; Then add the following Code to the ApplicationDbContext class: NOTE: This code is dense and a little messy. Don't work about understanding the details here - just take a high level view and try to grasp the overall idea of how this code is mapping our code objects to database tables. In particular, the manner in which it models the foreign key relationships between tables. In the above, we are basically telling Entity Framework how to model our inheritance structure into the database. We can, however, tell EF to model our database in such a way that both of our derived classes can also utilize the same tables, and in fact extend them to include our custom fields. Notice how, in the code above, we first tell the modelBuilder to point the IdentityUser class at the table "AspNetUsers", and then also tell it to point ApplicationUser at the same table? We do the same thing later with ApplicationRole. As you can see, there is actually no getting away from either the IdentityUser or IdentityRole classes - both are used by the Identity system under the covers. We are simply taking advantage of polymorphism such that, at the level of our application, we are able to use our derived classes, while down below, Identity recognizes them as their base implementations. We will see how this affects our application shortly. Now, however, we can replace IdentityRole with ApplicationRole in most of the rest of our application, and begin using our new Description property. We will begin with our IdentityManager class. I did a little refactoring here while I was at it, so if you are following along, this code will look a little different than what you will find in the original project. Just paste this code in (but make sure your namespaces match!). I also added a few new using's at the top of the code file. We will also want to update our AddUsersAndRoles() method, which is called by the Seed() method in the Configuration file for EF Migrations. We want to seed the database with Roles which use our new extended properties: All we really did here was pass an additional argument to the CreateRole() method, such the the seed roles will exhibit our new property. Now, we need to make a few adjustments to our AccountController, View Models, and Views. In the previous article, we created a SelectRoleEditorViewModel which accepted an instance of IdentityRole as a constructor argument. We need to modify the code here in order to accommodate any new properties we added when we extended IdentityRole. For our example, we just added a single new property, so this is pretty painless: Recall that, in order to display the list of roles with checkboxes as an HTML form from which we can return the selection choices made by the user, we needed to define an EditorViewModel.cshtml file which corresponded to our EditorViewModel class. In Views/Shared/EditorViewModels open SelectRoleEditorViewModel.cshtml and make the following changes: To this point, we actually only have one View which displays our Roles - the UserRoles view, where we assign users to one or more Roles within our application. Once again, we really just need to add a table Header element to represent our new Description property: The Updated UserRoles View: Here is where you may want to think things through a little bit. Consider - the main reason for utilizing Roles within an ASP.NET application is to manage authorization. We do this by hard-coding access permissions to controllers and/or specific methods through the [Authorize] attribute. If we make roles createable/editable/deletable, what can possibly go wrong? Well, a lot. First off, if we deploy our application, then add a role, we really have no way to make use of the new role with respect to the security concerns listed above, without re-compiling and re-deploying our application after adding the new role to whichever methods we hope to secure with it. The same is true if we change a role name, or worse, delete a role. In fact, an ambitious admin user could lock themselves out of the application altogether! However, there are some cases where we might want to have this functionality anyway. If, for example, you are the developer, and you add some new role permissions via [Authorize] to an existing application, it is more convenient to add the new roles to the database through the front-end than by either manually adding

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it harder for them to make their living on the coast. Residents of Tragadi Bandar claim in a lawsuit filed April 23 in U.S. federal court in Washington, D.C., that warm water discharged by the Tata plant has driven fish away from the intertidal zone, where the Waghers used to practice pagadiya, a traditional method of setting up nets and harvesting the fish at low tide. The returns from boat fishing, which takes place farther from shore, have also fallen off. “You see this produce here?” says Jam, sweeping his arm across a view of his bandar, one of several fishing settlements along the gulf. Burlap bags stuffed with dried Bombay duck sit on the sand waiting for market. “We used to get this much business in one day. Now it takes 15.” Yunus Suleman Gadh and other fisherfolk on Kutadi Bandar discuss how the Tata plant has harmed both their livelihoods and their health. Sami Siva / International Consortium of Investigative Journalists Jam and his neighbors are among the uncounted: people the World Bank Group and its borrowers have ignored in their push to create dams, power plants and other projects. The global institution’s two main lenders — the World Bank, which lends to governments, and the International Finance Corporation, which lends to corporations such as Tata — have repeatedly failed to make sure people harmed by big projects get counted, an investigation by the International Consortium of Investigative Journalists has found. Both lenders have detailed policies that require that their borrowers identify people whose homes or land will be lost or livelihoods will be damaged as a result of the projects they finance. When “project-affected people” are identified, borrowers must resettle them into new homes or help restore their livelihoods. But if people don’t get counted, they’re unlikely to get help from the lenders and their borrowers in putting their lives back together. In some cases, the IFC and the World Bank have declined to count entire populations that claim they’ve been harmed by projects backed by the lenders. In Kenya and Ethiopia, indigenous groups claim that World Bank cash bankrolled mass evictions that targeted them for threats, violence or arbitrary arrests. The World Bank denies its money was used for these evictions. What Is The World Bank? The World Bank Group is the globe’s most prestigious development lender, bankrolling hundreds of government projects each year in pursuit of its high-minded mission: to combat the scourge of poverty by backing new transit systems, power plants, dams and other projects it believes will help boost the fortunes of poor people. Read more » World Bank Group IBRD IDA IFC International Bank for Reconstruction and Development, one of the two lending arms traditionally considered to be the World Bank International Development Association, one of the two lending arms traditionally considered to be the World Bank International Finance Corporation, the World Bank’s private-lending arm Typically lends to middle-income governments, also some creditworthy low-income countries Typically lends to low-income governments Typically lends to private firms in developing (low- to middle-income) countries Founded in 1944 Founded in 1960 Founded in 1956 FY 2014 commitments $18.6 billion FY 2014 commitments $22.2 billion FY 2014 commitments $17.3 billionn Lends at market rate Guarantees loans Lends at low interest rate Lends at market rate Guarantees loans Invests in private companies 1. IBRD International Bank for Reconstruction and Development, one of the two lending arms traditionally considered to be the World Bank Typically lends to middle-income governments, also some creditworthy low-income countries Founded in 1944 FY 2014 commitments $18.6 billion Lends at market rate Guarantees loans 2. IDA International Development Association, one of the two lending arms traditionally considered to be the World Bank Typically lends to low-income governments Founded in 1960 FY 2014 commitments $22.2 billion Lends at low interest rate 3. IFC International Finance Corporation, the World Bank's private lending arm Typically lends to private firms in developing (low- to middle-income) countries Founded in 1956 FY 2014 commitments $17.3 billion Lends at market rate Guarantees loans Invests in private companies World Bank Annual Report Sources: Congressional Research Service In other cases, the World Bank has acknowledged that large numbers of people would be harmed by development initiatives, but allowed its borrowers to underestimate the real number. A 2012 internal review of nine World Bank-supported projects found that the number of affected people turned out to be, on average, 32 percent higher than the figure reported by the bank before approving the initiatives, understating the number of people affected by the nine projects by 77,500. This echoed a broader internal review in 1994, which looked at 192 projects and found that the real number of affected people averaged 47 percent higher than previously estimated. In March, a World Bank spokesman acknowledged that the bank-financed Nam Theun 2 dam in Laos has physically displaced or economically affected more than 75,000 villagers — a 50 percent increase over the 50,000 figure that the bank had reported before it approved the project in 2005. Independent researchers who have studied the project estimate that the number of people who have been harmed by the dam’s construction is larger than even bank’s updated number — reaching as high as 130,000 to 150,000. Bruce Shoemaker, a researcher on natural resources issues who worked on the independent review, says villagers downstream from the dam have suffered a drop in wild fish catches, excessive flooding of their rice fields and other impacts on their livelihoods. The failure by World Bank and Laotian officials to recognize the dam’s full effects on people above and below the dam means that the compensation offered to farmers and fisherfolk “didn’t come close to making up for their losses,” Shoemaker says. World Bank officials say they disagree with the larger estimate reached by Shoemaker and his co-researchers. “We are always willing to consider independent studies that focus on our projects,” David Theis, a bank spokesman, said in a written statement. “In this case, our extensive and detailed research and analysis has yielded different facts, which we stand by.” The bank says most people affected by Nam Theun 2 are better off than they were before, with surveys showing many families having more savings and assets and fewer underweight children. The bank says the increase in the numbers of people identified as being affected by the dam came because the project’s managers used a broader definition of affected households. In other cases, bank officials have attributed shifting numbers for people harmed by projects to later expansions in projects’ size or to population growth during projects’ long time windows. Theis said that despite the complex challenges of keeping track of people affected by development, “we are going to be extremely vigilant about our work in this area. When our work does involve relocation, we will do so as long as we can improve or at least restore people’s incomes and living conditions.” Wagher fishermen head into the gulf one afternoon. The water discharged by the Tata power plant is often hotter than the seawater, altering the marine ecosystem, an independent fact-finding team found. Sami Siva / International Consortium of Investigative Journalists Early Warning The problem of undercounting resonates in the Indian state of Gujarat, the site of a mammoth debacle that was supposed to transform the World Bank’s approach to development and displacement. In 1985, the bank pledged $450 million to finance the Sardar Sarovar dam and canal, the keystone of an effort to turn the Narmada River into a series of reservoirs that would serve the state’s most drought-prone regions. The bank estimated in 1987 that 60,000 people would be affected by the project. By 2000, the World Commission on Dams, a study group co-sponsored by the World Bank, put the figure at more than 200,000. Current estimates from NGOs monitoring the project indicate more than 250,000 will be impacted by the dam, which is in now in its final stages of construction. Many of the displaced, like the Wagher fishing families, had no title to the land they occupied. World Bank policies explicitly state that residents without title still qualify for compensation and resettlement assistance. Planning for Sardar Sarovar began with an “elaborate Government pantomime of conducting studies to estimate the actual project costs and the impact it would have on people and the environment,” the famed Indian novelist and activist Arundhati Roy later wrote. “The World Bank participated wholeheartedly in the charade — occasionally it beetled its brows and raised feeble requests for more information on issues like the resettlement and rehabilitation of what it calls ‘PAPs’ — Project Affected Persons. (They help, these acronyms — they manage to mutate muscle and blood into cold statistics. PAPs soon cease to be people.) The merest of crumbs satisfied the Bank and it proceeded with the project.” Resistance was fierce. Protesters blocked roads and barred government officials from their villages. Some pledged to drown rather than leave their land. Police met Gandhi-style nonviolence with beatings and arrests. After activists launched a hunger strike, the World Bank agreed to an independent review by an expert panel. These experts found — in the words of one panelist — “a rather terrifying ignorance” on the bank’s part about the dam’s human consequences. No one knew how many people would be ousted, and there was little preparation, or even available land, for resettling

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their mates when their humans left? Why did they stay and get sick? Lilith walked back to the settlement, a long crude basket filled with breadnuts on her back. She found the male and female ministering to their ooloi holding it between them and entangling its head and body tentacles with their own. Wherever the three touched, tentacles joined them. It was an intimate, vulnerable position, and other ooloi lounged nearby, guarding without seeming to guard. There were also a few humans watching. Lilith looked around the settlement, wondering how many of the humans not present would not come back from their day of wandering or food gathering. Did those who left come together on some other part of the island? Had they built a shelter? Were they building a boat? A wild thought struck her: What if they were right? What if they somehow were on Earth? What if it were possible to row a boat to freedom? What if, in spite of all she had seen and felt, this was some kind of hoax? How would it be perpetrated? _Why_ would it be perpetrated? Why would the Oankali go to so much trouble? No. She did not understand why the Oankali had done some of what they had done, but she believed the basics. The ship. The Earth, waiting to be recolonized by its people. The Oankali's price for saving the few remaining fragments of humanity. But more people were leaving the settlement. Where were they? What if—The thought would not let her alone no matter what facts she felt she knew. _What if the others were right?_ Where had the doubt come from? That evening as she brought in a load of firewood, Tate blocked her path. "Curt and Celene are gone," she said quietly. "Celene let it slip to me that they were leaving." "I'm surprised it took them so long." "I'm surprised Curt didn't brain an Oankali before he left." Nodding in agreement, Lilith stepped around her and put down her load of wood. Tate followed and again planted herself in Lilith's path. "What?" Lilith asked. "We're going too. Tonight." She kept her voice very low—though no doubt more than one Oankali heard her. "Where?" "We don't know. Either we'll find the others or we won't. We'll find something—or make something." "Just the two of you?" "Four of us. Maybe more." Lilith frowned, not knowing how to feel. She and Tate had become friends. Wherever Tate was going, she would not escape. If she did not injure herself or anyone else, she would probably be back. "Listen," Tate said, "I'm not just telling you for the hell of it. We want you to go with us." Lilith steered her away from the center of the camp. The Oankali would hear no matter what they did, but there was no need to involve other humans. "Gabe has already talked to Joe," Tate said. "We want—" "Gabe what!" "Shut up! You want to tell everyone? Joe said he'd go. Now what about you?" Lilith stared at her hostilely. "What about me?" "I need to know now. Gabe wants to leave soon." "If I leave with you, we'll leave after breakfast tomorrow morning." Tate, being Tate, said nothing. She smiled. "I didn't say I was going. All I mean is that there's no reason to sneak away in the night and step on a coral snake or something. It's pitch black out there at night." "Gabe thinks we'll have more time before they discover we're gone." "Where's his mind—and yours? Leave tonight and they'll notice you're gone by tomorrow morning—if you don't wake everyone on your way out by tripping over something or someone. Leave tomorrow morning and they won't notice you're gone until tomorrow night at dinner." She shook her head. "Not that they'll care. They haven't so far. But if you want to slip away, at least do it in a way that will give you a chance to find shelter before nightfall—or in case it rains." "When it rains," Tate said. "It always rains sooner or later. We thought... maybe once we were clear of this place, we'd cross the river, head north, keep heading north until we found a dryer, cooler climate." "If we are on Earth, Tate, considering what was done to Earth and especially to the northern hemisphere, south would be a better direction." Tate shrugged. "You don't get a vote unless you come with us." "I'll talk to Joe." "But—" "And you ought to get Gabe to help you with your acting. I haven't said a thing you and Gabe hadn't already thought of. Neither of you is stupid. And you, at least, are no good at bullshitting people." Characteristically, Tate laughed. "I used to be." She sobered. "Okay, yeah. We've pretty much worked out the best way of doing it—tomorrow morning and south and with someone who probably knows how to stay alive in this country better than anyone but the Oankali." There was a silence. "We really are on an island, you know," Lilith said. "No, I don't _know_ ," Tate answered. "But I'm willing to take your word for it. We'll have to cross the river." "And in spite of what we see on what seems to be the other side, I believe we'll find a wall over there." "In spite of the sun, the moon and the stars? In spite of the rain and the trees that have obviously been here for hundreds of years?" Lilith sighed. "Yes." "All because the Oankali said so." "And because of what I saw and felt before I Awoke you." "What the Oankali let you see and made you feel. You wouldn't believe some of the stuff Kahguyaht has made me feel." "Wouldn't I?" "I mean, you can't trust what they do to your senses!" "I knew Nikanj when it was too young to do anything to my senses without my being aware of it." Tate looked away, stared toward the river where the glint of water could still be seen. The sun—artificial or real—had not quite vanished and the river looked browner than ever. "Look," she said, "I don't mean anything by this, but I have to say it. You and Nikanj..." She let her voice die, abruptly looked at Lilith as though demanding a response. "Well?" "Well, what?" "You're closer to him—to it—than we are to Kahguyaht. You..." Lilith stared at her silently. "Hell, all I mean is, if you won't go with us, don't try to stop us." "Has anyone tried to stop anyone from leaving?" "Just don't say anything. That's all." "Maybe you are stupid," Lilith said softly. Tate looked away again and shrugged. "I promised Gabe I'd get you to promise." "Why?" "He thinks if you give your word, you'll keep it." "Otherwise, I'll run and tell, right?" "I'm beginning not to care what you do." Lilith shrugged, turned and started back toward camp. It seemed to take Tate several seconds to see that she meant it. Then she ran after Lilith, pulled her back away from the camp. "All right, I'm sorry you're insulted," Tate rasped. "Now are you going or aren't you?" "You know the breadnut tree up the bank—the big one?" "Yes?" "If we're going, we'll meet you there after breakfast tomorrow." "We won't wait long." "Okay." Lilith turned and walked back to camp. How many Oankali had heard the exchange? One? A few? All of them? No matter. Nikanj would know in minutes. So it would have time to send for Ahajas and Dichaan. It would not have to sit and go catatonic like the others. In fact, she still wondered why the others had not done it. Surely they had known that their chosen humans were leaving. Kahguyaht would know. What would it do? Something occurred to her suddenly—a memory of tribal people sending their sons out to live for a while alone in the forest or desert or whatever as a test of manhood. Boys of a certain age who had been taught how to live in the environment were sent out to prove what they had learned. Was that it? Train the humans in the basics, then let them go out on their own when they were ready? Then why the catatonic ooloi? "Lilith

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High blood pressure; the condition that occurs as a result of high blood pressure. _Some over-the-counter cough, cold, and allergy medicines tend to cause elevated blood pressure, and include a warning that they may be hazardous to those suffering from HYPERTENSION._ **hypocrite** _(HIP-uh-krit), noun_ A person pretending to be something he or she is not, or pretending, for the sake of appearance, to have high moral beliefs; a person who does not act according to espoused beliefs. _In Marilyn's view, a marriage counselor who advised others to live up to the ideal of fidelity but who cheated on his own wife was the worst kind of HYPOCRITE._ **ignoble** _(ig-NO-bull), adjective_ Dishonorable in nature. In contrast with ignominious (see below), ignoble carries the sense of baseness or lowness. _Peter's IGNOBLE aims were well known to all in the room._ **illicit** _(ih-LISS-it), adjective_ Illegal or morally unjustifiable. Illicit refers to something not sanctioned by custom or law. _We all know now that the money was acquired through ILLICIT means, don't we?_ **imbecility** _(im-buh-SILL-ih-tee), noun_ Foolishness; simplemindedness. _Although he lamented the IMBECILITY of mainstream television, Arnie was not above an occasional viewing of American Gladiators or Geraldo._ **improvident** _(ihm-PRAHV-ih-dent), adjective_ Describes someone who does not plan well for the future or one who acts without thinking. _It was cute when he was younger, but now Mike's IMPROVIDENT behavior just makes him look like a total loser._ **inane** _(in-ANE), adjective_ Pointless or lacking in substance. Something that is inane is vacuous. _Among other INANE suggestions, Jeff proposed painting the lunchroom in a polkadot pattern._ **indict** _(in-DITE), verb_ To charge formally with a crime or offense. (See, for comparison, the entry for indite.) _Rumors that Mr. Brown would soon be INDICTED for his part in the scandal swept the city._ **indiscreet** _(in-dih-SKREET), adjective_ Lacking good judgment and prudence; apt to run one's mouth about things that others would like left private. _Don't get alcohol near Melanie. It makes her go from prudent to INDISCREET in less than sixty seconds!_ **infernal** _(in-FER-nul), adjective_ Fiendish; devilish. Infernal means, literally, "of or pertaining to hell." It is often used as a mild expletive. _This INFERNAL copier keeps breaking down!_ **infidelity** _(in-fi-DEL-ih-tee) noun_ The quality or act of having been untrue or inconsistent with a (often implied) standard. Infidelity is often used to describe extramarital affairs. _Although Gwen suspected her husband of INFIDELITY, she had not come across any tangible proof._ **influenza** _(in-floo-EN-zuh), noun_ A contagious respiratory virus characterized by inflammation of the mucous membrane, fever, prostration, aches, and pains. _David was still weak from his bout with INFLUENZA._ **ingrate** _(IN-grate), noun_ An ungrateful person. A person who does not show the proper respect or gratitude toward someone who has provided help might be called an ingrate. _He lived with us for six months, but that INGRATE Ralph hasn't even written in over two years._ **iniquity** _(ih-NIK-wih-tee), noun_ Injustice or immoral action. Iniquity derives from the Latin for "unfairness." _The many INIQUITIES suffered by American Indians at the hands of government authorities is only now being widely acknowledged._ **insidious** _(in-SID-ee-uss), adjective_ Designed to entrap; happening or spreading harmfully but subtly; stealthily and seductively treacherous. _Mark's chess games were full of INSIDIOUS traps meant to lull his opponent into a sense of complacency._ **insipid** _(in-SIP-id), adjective_ Lacking in vigor; dull. Insipid (usually applied to bland ideas, personalities, or works of art) derives from the Latin for "without taste." _In Frank's opinion, the novel's plot was INSIPID and left much to be desired._ **insolent** _(IN-suh-lnt), adjective_ Rude and arrogant. That which is insulting or disrespectful (especially speech) could be considered _insolent_. _Her INSOLENT retorts to Joan's well-intentioned queries stunned the dinner party._ **insubordinate** _(in-suh-BOR-din-it), adjective_ Failing to accept or obey proper authority. In the military, an enlisted man who insults an officer could be accused of an insubordinate act. _Frank, not eager to be branded INSUBORDINATE, did his best to carry out the colonel's strange orders._ **irascible** _(ih-RASS-uh-bul), adjective_ Easily angered. Those who are prone to fits of temper are irascible. _Sebastian, an IRASCIBLE man, did his best to put on a show of conviviality when he visited his in-laws, most of whom irritated him._ **jaded** _(JAY-dud), adjective_ Worn out; dulled or satiated due to overindulgence. _Her parents thought that providing Tracy with everything her heart desired as a child would make her a happy person, but she grew up to be a JADED and selfish woman._ **jaundice** _(JON-diss), noun_ A yellowish tint to the body's skin, fluids, and tissues as a result of the buildup of excessive bile; also, a biased, hostile attitude. _The cosmetics saleswoman tried to convince her that the makeover had given her a tanned appearance, but Shawna worried that she looked like she had JAUNDICE._ **lacerated** _(LASS-uh-ray-tud), adjective_ Cut, torn, ripped, or mangled. _Because I LACERATED my finger with the scissors while I was on the job, I was eligible to file a workers' compensation claim._ **lackadaisical** _(lack-uh-DAZE-ih-kul), adjective_ Lacking spirit or energy; languid. _I was feeling rather LACKADAISICAL last Sunday, so I stayed in bed all day and watched football games instead of mowing the lawn._ **lackluster** _(LACK-lus-tur), adjective_ Dull; not shiny or brilliant. _Wanda's LACKLUSTER performance as Hedda Gabler led one critic to remark that she probably had a long career ahead of her in the theater—as a stage weight._ **libel** _(LIE-bull), noun_ A written, printed, or pictorial statement or assertion that is unjustly negative, defaming, or hurtful to one's character and reputation. _Several celebrities have sued the supermarket tabloid for LIBEL, but the parade of lurid and preposterous headlines has continued unabated._ **libertine** _(LIB-ur-teen), noun_ One who lives life unconcerned and unrestrained by popular convention or morality; a promiscuous person, especially a man. _Presumably because he is divorced, my elderly grandmother refers to my fiance Eric as "that LIBERTINE," but everyone else in my family thinks he's wonderful._ **licentious** _(lie-SENN-shuss), adjective_ Having little or no moral restraint, especially with regard to sex. _After months of watching Gary leave the nightclub with one woman after another, Paul finally decided to tell Maureen of her husband's LICENTIOUS behavior._ **lip-sync** _(LIP-sink), verb_ To simulate a live singing performance by mouthing along to a record. _It is common these days for recording artists to LIP-SYNC for the bulk of a " live" concert._ **litigious** _(lih-TIJ-us), adjective_ Overly inclined to engage in lawsuits. Litigious can also mean "of or

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-3,15-dione; 10-(benzyloxy)-5-ethyl-9-fluoro-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9,10-difluoro-3,15-dioxo-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-5-yl 2-aminoacetate; 5-ethyl-9,10-difluoro-3,15-dioxo-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-5-yl 3-aminopropanoate; 2,9-diethyl-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 9-ethyl-9-hydroxy-2-methyl-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 2-benzyl-9-ethyl-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; 2-benzyl-9-ethyl-5-fluoro-9-hydroxy-1,2,3,9,10,16-hexahydro-13H-[1,3]oxazino[5,6-f]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-11,14-dione; (+)-5-ethyl-9,10-difluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; (+)-1-[9-chloro-5-ethyl-5-hydroxy-10-methyl-3,15-dioxo-4,5,13,15-tetrahydro1H,3H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinolin-12-ylmethyl]-4-methylhexahydropyridine; or a pharmaceutically acceptable salt of the latter. The invention more particularly relates to the following compounds corresponding to the formula (HCPT): 5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5,12-diethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline3,15-dione; 8-ethyl-8-hydroxy-2,3,8,9,12,15-hexahydro-10H,13H-[1,4]dioxino[2,3-g]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-10,13-dione; 10-(benzyloxy)-5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 11-[(dimethylamino)methyl]-5-ethyl-5,10-dihydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 9-chloro-5-ethyl-5-hydroxy-10-methyl-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9,10-difluoro-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 7-ethyl-7-hydroxy-7,8,11,14-tetrahydro-9H,12M-[1,3]dioxolo[4,5-g]oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-9,12-dione; 9-chloro-5-ethyl-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-5-hydroxy-10-methoxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 9,11-dichloro-5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-9-fluoro-5-hydroxy-10-methyl-1,4,5,13-tetrahydro-3H,15H-oxepino[3xe2x80x2,4xe2x80x2:6,7]indolizino[1,2-b]quinoline-3,15-dione; 5-ethyl-10-fluoro-5-hydroxy-1,4,5,13-tetra

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Gas: Detection around M Dwarf TWA 7' --- Introduction {#sect:intro} ============ Planetesimal belts, also known as debris disks, are extrasolar Kuiper and asteroid belt analogues, detected around a significant fraction of nearby, main-sequence solar-type (FGK) and A stars [for a review, see e.g. @Hughes2018; @Wyatt2018]. Detectable belts are collision-dominated environments, where the mass of the observed dust and larger planetesimals in a so-called *collisional cascade* depletes over time [as observed, e.g. @Wyatt2007b; @Holland2017; @Sibthorpe2018]. To date, 19 of these belts have been detected in one or several gas tracers. Detection of gas in planetesimal belts has the potential to inform us about exocometary compositions [@Matra2017b; @Matra2018a], particularly during the $\sim$10-100 Myr period when terrestrial planet formation is still ongoing, and volatile delivery events through exocomets may be commonplace [e.g. @Morbidelli2012]. CO dominates the number of detections (17/19), in part thanks to the unprecedented sensitivity of the Atacama Large Millimeter/submillimeter Array (ALMA). For many systems, it remains debated whether the gas is primordial or secondary in origin, where primordial gas is a long-lived remnant of the protoplanetary disk [@Kospal2013], whereas secondary gas is second-generation like the dust, produced by exocometary gas release [e.g. @Zuckerman2012; @Matra2015]. In five of these belts, the CO masses and line opacities have been well established, and the resulting low CO masses and optically thin CO lines can only be explained by a second generation origin [@Dent2014; @Marino2016; @Marino2017a; @Matra2017a; @Matra2017b; @Booth2018]. The origin of gas for the more massive CO-bearing belts remains unconfirmed, but there are indicators suggesting an absence or a significant depletion of H$_2$, which would point toward a secondary origin for them, too [e.g. @Hughes2017; @Higuchi2017]. A puzzling outcome of the first global analysis of the CO detections is a significantly higher occurrence rate of CO in belts around A stars compared to lower luminosity stars [@Moor2017]. Indeed, no detection has been reported to date around stars of type later than F, which constitute the overwhelming majority of stars in our Galaxy. In this work, we aim to understand how the presence of CO gas in a planetesimal belt is affected by its stellar host, and explain the origin of the decreasing CO occurrence rates around stars of decreasing stellar luminosity. We do so by presenting the first ALMA detection of CO in a planetesimal belt around an M3-type [@Ducourant2014] dwarf, TWA 7. This nearby star [34.0 pc, @Gaia2018] is part of the TWA association [@Webb1999], setting its age at $\sim$10 Myr [@Bell2015]. Its infrared excess was detected by *Spitzer* [@Low2005] and confirmed by *Herschel* [@RiviereMarichalar2013]. The first, scattered light image of the outer regions of the belt was obtained by HST [@Choquet2016], and more recent SPHERE data resolve the belt’s inner regions showing broad emission from a face-on ring extending from $\sim$20 to at least $\gtrsim70$ au [@Olofsson2018]. Unresolved submillimeter emission was detected by the JCMT [@Matthews2007]. However, ALMA observations recently showed that the JCMT flux is actually dominated by an unrelated source $\sim6.6\arcsec$ offset from the star (likely a submillimeter galaxy), although the fainter-than-expected belt is also detected and marginally resolved [@Bayo2018]. We here analyze the CO cube obtained as part of the same ALMA dataset as described in @Bayo2018. In §\[sect:obs\], we summarize the interferometric observations, including their calibration and imaging. §\[sect:res\] presents our analysis of the CO data and a derivation of physical parameters from measured quantities. In §\[sect:disc\], we demonstrate the exocometary origin of the gas, and examine how of the exocometary release process differs around M stars compared to more luminous stars. Finally, we discuss the origin of the stellar luminosity dependence of the CO detection rates in the context of exocometary gas release. We conclude by summarizing our findings in §\[sect:concl\]. Observations {#sect:obs} ============ TWA 7 was observed by ALMA in Band 7 using the 12m array in 2016. Three observations were obtained, one with 42 antennas in a compact configuration pointed at coordinates RA: 10h42m29.904s Dec: -33d40m17.098s, and two with 36 antennas in a more extended configuration pointed at coordinates RA: 10h42m30.413s Dec: -33d40m16.700s, altogether spanning baselines from 15.1 m to 3.1 km. Further details of the observations can be obtained in @Bayo2018. Standard calibrations were applied to each dataset using the ALMA pipeline in CASA v5.1.0. A CO visibility dataset was produced covering $\sim$1200, 244.141 kHz-wide channels around the transition frequency (345.796 GHz), with continuum emission subtracted from it using the *uvcontsub* CASA task. For continuum imaging, we considered all 6.9 GHz covered by the 4 spectral windows of each of the observations. For both CO and continuum, calibrated visibilities from the different observations and configurations were imaged both separately and together using the *tclean* task within CASA, in mosaic mode with multiscale deconvolution. To improve sensitivity to extended emission originating from the belt, we use natural weighting and further apply a 2$\arcsec$ u-v taper to the visibilities prior to imaging. The final CO data cube reaches an RMS sensitivity of 7 mJy/beam in a 244.141 kHz channel (corresponding to 0.21 km/s at 345.796 GHz) for a synthesized beam size of $1.8\arcsec\times 1.7\arcsec$ (62$\times$58 au at the distance of the star from Earth). The continuum image has an RMS noise level of 0.07 mJy/beam for the same synthesized beam size. ![CO J=3-2 spectra of the belt around TWA 7, spatially integrated over the region where continuum is detected at the $\sim$2$\sigma$ level. The top (red) spectrum is obtained without any spectral filtering, whereas the center and bottom spectra are obtained by shifting the 1D spectra at each pixel location by the negative of their expected Keplerian velocity at that location. Two possible signs of the velocity are possible, depending on whether the East side of the belt is moving away or towards us, leading respectively to the green and blue spectra. The grey region indicates the $\pm1\sigma$ confidence interval for the stellar radial velocity [@Gagne2017]. The green shaded region represents the best-fit Gaussian profile to the spectro-spatially filtered emission, used to quantify the integrated line flux.[]{data-label="fig:1dspectra"}](TWA7_CO32_allspectra_vnoselfcal_compandext_smallerpix.pdf) Results and Analysis {#sect:res} ==================== Spectro-spatial filtering: CO J=3-2 detection {#sect:spectrospatial} --------------------------------------------- No strong emission is observed after quick inspection of the CO data cube around the radial velocity of the star [11.9$\pm$0.4 km/s in the heliocentric frame, @Gagne2017]. Following the method of @Matra2015 [@Matra2017b], we apply a spectro-spatial filtering technique in order to boost the S/N and achieve maximum sensitivity (Fig. \[fig:1dspectra\]). First, we simply spatially integrate over the region within $\sim$3.5" from the star where continuum emission from the belt is detected above the 2$\sigma$ level. This produces the red spectrum, where a hint of a Keplerian double-peaked profile already emerges from the noise around the expected stellar velocity. To test whether this signal truly originates from circumstellar gas, we then assume that CO orbits with the Keplerian velocity field expected around a star of 0.55 M$_{\odot}$ [@Neuhauser2000], for a disk with an inclination (13$^{\circ}$) and position angle (PA, 91$^{\circ}$) as derived from high resolution dust imaging in the near-IR [@Olofsson2018]. The unknown rotation direction leads to two possible velocity fields, with the East side of the disk moving away from Earth or towards Earth. For each of the two possible velocity fields, we assign each pixel a given expected radial velocity and shift the 1d spectrum in that pixel along the frequency (velocity) axis, by the negative of its assigned radial velocity. Then, we spatially integrate over the region where continuum emission is detected, to produce the green and blue spectra. We find that the detection is significantly boosted from a peak S/N of 3.7$\sigma$ to 6.4$\sigma$ for a Keplerian velocity field where the East side of the disk is moving away from us, whereas no boost is achieved when the sign of the velocity field is inverted.

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over the years. He is shown defeating the Destroyer. Red and Blue Superman make an appearance in the Superman 75 Year Anniversary short. In the animated series, Justice League Action'', Lex Luthor created a kryptonite-weapon to destroy Superman, but instead it split him into Superman Red and Superman Blue. Each Superman had half of the original's power, but Superman Red was aggressive and evil while Superman Blue was gentle and good. The weapon even did the same thing to Wonder Woman, Batman and Luthor, and the reds plotted to affect the entire world, except for Luthor Red, who was actually good and returned everything to normal. References Category:Comics by Dan Jurgens Category:Comics by Louise Simonson{ "name": "books.toscrape", "request": { "type": "base", "url": "http://books.toscrape.com/" }, "fields": [ { "name": "title", "selector": "h3 a", "extractor": { "types": [ "href", "text" ], "params": { "includeIfEmpty": false } } }, { "name": "image", "selector": ".thumbnail", "extractor": { "types": [ "src", "alt" ], "params": { "includeIfEmpty": false } } }, { "name": "price", "selector": ".price_color", "extractor": { "types": ["text"], "params": { "includeIfEmpty": false } } } ], "paginator": { "selector": ".next a", "attr": "href" }, "format": "json" }Sneak a peek into the music business through brand new eyes. “And I’ll just keep singing because that’s what I do. That’s what I am. I’m a singer. Not a producer, not a writer, not a human. I’m a singer. But, I’ll get to the top if it’s the last thing I do.” – Prologue (Soundtrack 2 My Life) Note:Blueprints of Winnie is unfinished, and will likely remain so. It contains some harsh language. Editorial Reviews Feb 26, 2013: This is a fun little serial about a teen pop singer who knows she can be more. She gets a few breaks, but also falls right into a tabloid sex scandal and maybe gets doublecrossed too . . . but then the story is left hanging (as of Aug 2012). I like the character and the tone. She’s a little cynical, but also puts her heart into life and jumps in with both feet. "I dive head first into the muddy, shallow side of Hollywood. I thought I had to think about it, but in the end it really was a no-brainer." The story had a few enthusiastic followers, so it’s too bad it disappeared without explanation. But what’s there is fun to read, and maybe it will come back . . . . 1 of 1 members found this review helpful. Help us improve! Register or log in to rate this review. Most Helpful Member Reviews No member reviews yet. Your review Register or log in to rate, recommend, review, or bookmark this story.International Auditing and Assurance Standards Board The International Auditing and Assurance Standards Board (IAASB) is an independent standards body which issues standards, like the International Standards on Auditing, quality control guidelines and other services, to support the international auditing of financial statements. It is a body supported by the International Federation of Accountants (IFAC). The Public Interest Oversight Board provides oversight of the IAASB, ensuring that the standards are in the public interest. To further ensure proposed standards are in the public interest the IAASB consults its Consultative Advisory Group, which is composed of standard setters, various international organizations from the private and public sectors, and regulators. Representatives include a balance of users and prepares of financial statements, and should to the extent practicable be balanced geographically. Founded in March 1978 as the International Auditing Practices Committee (IAPC), the IAASB's current strategic themes include: Supporting global financial stability Enhancing the role, relevancy and quality of assurance in an evolving world Facilitating adoption and implementation of the standards it sets See also International Organization of Supreme Audit Institutions International Public Sector Accounting Standards References External links Category:International accounting organizations Category:Auditing standards Category:International standardsAt this point in my life, I go through most days without making a new friend. Sure, an acquaintance or associate here and there, but fewer opportunities to connect with individuals in meaningful, emotional ways. So when I was presented with the chance to build a special friendship with Philadelphia Eagles linebacker Jordan Hicks, I jumped in my car and set forth on a journey neither of us will soon forget. Jordan exemplifies strength, and not just with those muscles of his. He's an inspiration because of how he's been there for everyone in his life, no matter the circumstance. Combine that with his generosity and genuineness and you've got yourself the foundation for a good friend. I guess you could say it was just my lucky day. How could I ever prove myself worthy, though? How do I show him what we have in common and what he would get from our friendship? How do I tell him who "Will" is? It may be tough, but if there's a friend at the end of the tunnel, I'll do whatever it takes. So what do you say, Jordan Hicks: Will you be my friend?characterDef { skin "cvops" mesh "models/players/temperate/axis/cvops/body.mdm" animationgroup "animations/human_base.anim" animationscript "animations/scripts/human_base.script" undressedCorpseModel "models/players/temperate/common/naked.mdm" undressedCorpseSkin "axis_cvops" hudhead "models/players/hud/head.md3" hudheadanims "animations/human/heads/base.anim" hudheadskin "models/players/hud/axis_cvops.skin" } Abstract The paper, starting from the consideration of the main literature on sustainable tourism, is focalized on the analysis of sustainable tourism demand in developed countries. In previous studies, the research group has identified the framework of "4L Tourism", an emerging form of tourism that synthesizes the main tourist motivations in four assets (Landscape, Leisure, Learning, Limit), which require specific tourist offer and products. The paper is based on a field research carried out in Italy on CTS travellers. The research, deliberately aimed to a tourist population with specific behavioural and motivational features, allowed to study in deep the importance of the "4L Tourism" dimensions, highlighting the possibility to graduate the sensibility of tourists in respect with the single dimensions. Coherently with a significant stream of literature on sustainable tourism demand, the analysis enabled to identify two profiles ("4L Tourist hard-path" and " 4L Tourist soft-path") in relation to the intensity of the motivation and to the importance of the single component of the trip. The results of the research permitted, from a managerial point of view, to assess the expectations and the behaviours of "4L Tourists", in order to set up the tourist offer of tourist destinations and organisations, allowing them to follow an emerging global trend in the market with appropriate strategies.Clairvoyants, with the use of their psychic faculties, have observed that every person is surrounded and interpenetrated by a luminous energy body called the bioplasmic body. It is also called as the energy body or Etheric double. This energy body interpenetrates the visible physical body and extends beyond it by four or five inches. It follows the contour of the visible physical body and is called the inner aura. It is unfortunate that many of us lead hurried lives and are too busy to take care of ourselves the way we should — eating well, getting sufficient exercise, and taking the time to get the rest we really need to increase our energy and maintain our mental, emotional, and physical well-being. It’s fortunate, though, that for the stressed person seeking greater vitality, health — and tranquility — amid the hustle of the modern world, there is one particular healing technology that offers a simple, easy-to-implement solution: Pranic Healing®. Signs of Inferiority complex person Inferiority complex symptoms When a person feels that he is less worthy than others, that he is not adequate and that he is worthless then it is said that he is suffering from inferiority complex.Permutation blocking path integral Monte Carlo approach to the uniform electron gas at finite temperature.

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fight to keep myself from swaying as the camp spread open in front of me. It was just that some things had changed in the months I'd been gone. The lower level of the Infirmary had been little more than a hallway of beds and curtains, but all of those were gone now, replaced by stacked, unlabeled boxes. As we moved across the tile, the plastic in my shoe clicking with each stride, I saw PSFs bringing more up from the back rooms and offices. Their curious gazes followed us all the way outside into the pouring rain. Gunmetal-gray skies always drew out the vibrant green of the grass and the trees surrounding the fence. The curtain of water falling around us in sheets didn't dampen the effect in the slightest, nor did it drive away the earthy smell that immediately sent my senses into an overload of visceral memory. I bit my lip and shook my head. It's different now, I reminded myself. You're in control. You are getting out of here. I tried to reach for the old, familiar numb nothing I had lived inside while in this camp, but couldn't find it. The soggy ground shifted under my feet as I found the muddy path. I looked down, and my eyes caught on the sight of the white slip-ons on my feet. The number 3285 stared back, splattered with filthy water and wilted grass. I took a steadying breath and forced myself forward. You're here for a purpose. You are going to get out of here. This was another Op. I could be hard and certain and fight here, too. There was no falling apart now. No giving into fear. Not if I was going to save the others. Rings of cabins curved in front of me, looking darker and smaller than I remembered. I saw holes in the roofs patched over with sheets of warped plastic. The wood paneling along the sides was warping, peeling as the remnants of the last snowstorm dripped down from the roofs. The cold ran like needles over my skin, pinching and stabbing until I finally gave in and started to shiver. The red brick Control Tower at the center of the cabins had darkened under the rain's touch, but there were still multiple PSFs out on the upper ledge, their guns following the paths of each line of drenched kids trudging up the paths from the Garden. Their Blue uniforms clung to their shoulders, the hollows of their stomachs. Most of the kids kept their heads down as they diverted around us, but I caught a few curious glances, all lightning-fast, under the watchful eye of their PSF escort. No—not PSF— I spun on my heel, watching as the soldiers at the end of the line marched on, backs straight, movements choreographed and stiff. They wore crimson vests over their black fatigues. I guided Laybrook off the path with the slightest bit of pressure on his arm, letting the next group pass by us to reach their cabins. Again, walking alongside them at the front and back of the two straight rows were the soldiers in crimson vests. No guns. No weapons of any kind. A warning trill sounded in my mind as the last group came toward us, and terrible suspicion solidified into shock. The red vests were keeping track of the kids, devoid of any emotion. They were young, faces still round and full. My age maybe, or a few years older. They were inserted in the places where the dwindling PSF force should have been. They were Reds. THERE WAS AN HOUR BETWEEN the last work shift, whether it was in the Garden, the Factory, or cleaning in the Mess Hall or Wash Rooms, and when they served dinner. The kids would be returned to their cabins, and each group was allotted a specific time to walk the distance between the buildings. It was a song that only worked if the camp hit each note exactly right. The kids were streams of blue and green, so deeply entrenched in playing their parts that they never stepped out, not even once, to dare interrupt the pace. Reds. God, the others had no idea. I had no way of warning them, and the closer I came to Cabin 27, the more it felt like this was already over. Laybrook followed me up to the cabin, unlocking the door and holding it open for me with a forced politeness. I stepped inside, my eyes meeting his pale ones for the last time. I plugged memories in over the truth, dropped in scenes of him roughing me up, dragging me around, and made him think he was as tough as he wanted to be. The door shut automatically as he turned and walked back into the rain. I knew, by the silence that had greeted me when the door opened, that the girls weren't back yet. They would have switched, just recently, from Factory to Garden duty, and likely were still trudging back through the mud, or waiting at the low fence for permission to move. The cabin—my cabin—was small enough to take in with a single turn. Brown upon brown, broken up only by the yellowing white sheets on the bunk bed. The smell of mildew mixed with a natural body odor, covering even the bland hint of sawdust from the wood. Patches of silver light streamed in through the cracks in the paneling. The wind whispered through the cabin, drawing me around the first few sets of bunks, toward the back wall. I stared at my bunk, a familiar hopeless despair crashing over me. I bit my lip again to keep from crying. Rain had come in through the nearby wall, slanting in to dampen the mattress. I moved toward it like I was underwater, barely feeling it as I sat down. My breath caught in my throat and stayed there as I looked up at the bottom of Sam's mattress. My fingers traced the shapes I had peeled off at night when I couldn't sleep. You left them here. A hand rose up, pressing against my chest, making sure my heart was still beating. You left them here, to live in this hell. "Stop," I whispered. "Stop." There was no way I could ever make up for it. There was no way to go back and change the decision I made that night to swallow Cate's pills. The only way out was forward. I am going to walk out of here. I am going to take every single one of them with me. The door to the cabin popped open. They were silent as they came in, lining the narrow space between the nearby bunks. The PSF came in, counting them off. Then, with a faint smirk, she turned and added me to the tally. The others knew better than to move before the uniform left and locked the door behind her, but nothing could have surprised me more than seeing Sam whirl around, something like hope on her face. Her honey-blond hair had been hastily braided back, and her face was streaked with black dirt. She looked tired, pushed past the point of exhaustion; but her stance, the hands on her hips, the expectant tilt of her head—that was Sam. That was all Sam. "Oh my God." Ellie, one of the older girls. She and Ashley had always tried the hardest to take care of the younger girls. Without her best friend standing shoulder to shoulder with her, I barely recognized her. There was a beat of stillness and then she was rushing toward me, climbing over the bunks that separated us. A good thing, too. I'm not sure I could have moved if I'd wanted to. How was it possible to be bursting with happiness at the sight of them, and still terrified about what they'd think? "Oh my God." Those three words over and over again. Ellie crouched down in front of me, her green shirt splattered with rain. She took my face between her freezing hands, a light touch that turned into a fierce grip once she seemed to accept I was real. "Ruby?" "I'm back," I choked out. The other girls bottlenecked the path between the bunks, and some, Sam included, simply crawled over the mattresses and frames that stood between them and me. Vanessa, Macey, Rachel, all of them, reaching out, touching my face, the hands that were limp in my lap. Not angry. Not accusing. Not afraid. Don't cry, I told myself, smiling even as my eyes burned behind my lashes. "They said that you died," Ellie said, still kneeling in front of me. "That it was IAAN. What happened? They took you away that night, and you never came back—" "I got out," I told them. "One of the nurses planned the whole thing. I met other kids like us and...we hid." The abbreviated truth would have to do—for now. I'd never bothered to ask Cate if the cameras could record sound in addition to video, but the sight of them gathered around me would be dangerous enough. We weren't supposed to touch each other. "But they found you?" This from Vanessa, dark eyes still wide with disbelief. "Do you know if they took Ashley, too? Have you heard anything about her?" "What happened?" I asked, careful to keep my tone measured. "They pulled her in to work in the Kitchen...maybe two months ago?" Ellie said. That wasn

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NON-PRECEDENTIAL DECISION - SEE SUPERIOR COURT I.O.P. 65.37 COMMONWEALTH OF PENNSYLVANIA : IN THE SUPERIOR COURT OF : PENNSYLVANIA : v. : : : SEAN ANTHONY MOFFITT : : Appellant : No. 614 WDA 2019 Appeal from the Order Dated March 11, 2019 In the Court of Common Pleas of Allegheny County Criminal Division at No(s): CP-02-CR-0002760-2001, CP-02-CR-0008340-1998, CP-02-CR-0009829-2005 BEFORE: OLSON, J., McCAFFERY, J., and MUSMANNO, J. MEMORANDUM BY OLSON, J.: FILED FEBRUARY 28, 2020 Appellant, Sean Anthony Moffitt, appeals from the March 11, 2019 order entered in the Court of Common Pleas of Allegheny County. We are constrained to quash this appeal. The record reveals the following chronology of events. On March 5, 2016, Appellant filed a writ of errors coram nobis, requesting the court to vacate his October 5, 2006 judgment of sentence.1 Appellant’s Writ of Errors ____________________________________________ 1 Appellant was originally charged with the following crimes: persons not to own or possess a firearm (18 Pa.C.S.A. § 6105); carrying a firearm without a license (18 Pa.C.S.A. § 6106(a)(1)); possession with the intent to deliver a controlled substance (“PWID”) (35 P.S. §780-113(a)(30)); possession of a controlled substance (35 Pa.C.S.A. § 780-113(a)(16)); and, receiving stolen property (18 Pa.C.S.A. § 3925). On October 5, 2006, Appellant entered into a negotiated plea deal in which he pled guilty to (1) persons not to own or possess a firearm, (2) possession of a controlled substance, and (3) receiving J-S08008-20 Coram Nobis, 3/5/16, at 1-27. The court denied Appellant’s writ on April 12, 2016. PCRA Court Order, 4/12/16, at 1. Appellant did not appeal. Thereafter, on June 9, 2016, Appellant filed a second writ of errors coram nobis. Appellant’s Second Writ of Errors Coram Nobis, 6/9/16, at 1-27. Additionally, on April 25, 2017, Appellant moved for the appointment of counsel. Appellant’s Motion for Appointment of Counsel, 4/25/17, at 1. Finally, on June 8, 2017, Appellant filed an amended writ of errors coram nobis. Appellant’s Amended Writ of Errors Coram Nobis, 6/8/17, at *1-4 (un-paginated). In his amended writ, Appellant asked the Post Conviction Relief Act (PCRA) court2 to vacate his judgments of sentence dated January 28, 1999,3 February 25, 2003,4 and October 5, 20065 because his counsel ____________________________________________ stolen property. Appellant was sentenced to 11 1/2 to 23 months incarceration. The other charges were withdrawn. 2 We are referring to the court as a PCRA court because, as discussed, Appellant’s writ of errors coram nobis should have been treated as a PCRA petition. 3On January 28, 1999, Appellant pled guilty and was sentenced to 11-23 months of incarceration for PWID (cocaine) (35 P.S. §780-113(a)(30). 4On February 25, 2003, Appellant entered a plea of nolo contendere and was sentenced to 18-36 months of incarceration for possession of a controlled substance (35 Pa.C.S.A. § 780-113(a)(16)) and PWID (cocaine) (35 P.S. §780-113(a)(30)). 5Appellant’s June 8, 2017 amended writ of errors coram nobis asked the PCRA court to vacate a judgment of sentence for PWID entered on October 5, 2006. Appellant’s Amended Writ of Errors Coram Nobis, 6/8/17, at *1 (un-paginated). As explained in footnote one, however, in October 2006 Appellant entered into a negotiated plea deal and was sentenced for the -2- J-S08008-20 failed to inform him that his convictions could be used in future cases to enhance his criminal record score. Id. As such, Appellant claimed, essentially, that counsel’s ineffectiveness caused him to enter unknowing and unintelligent, and therefore, invalid pleas. Id. On July 24, 2017, the PCRA court denied Appellant’s amended writ together with his motion for appointment of counsel. PCRA Court Order, 7/24/17, at 1. Appellant did not file a notice of appeal. Instead, on August 25, 2017, Appellant filed a motion for reconsideration, requesting that the PCRA court reconsider his “[p]etition for writ of error coram nobis.” Appellant’s Motion for Reconsideration, 8/25/17, at 1. The PCRA court, however, did not respond to Appellant’s motion until March 11, 2019, when it denied reconsideration. PCRA Court Order, 3/11/19, at 1. Appellant then filed a notice of appeal on March 25, 2019, challenging the denial of reconsideration. Preliminarily, we note that Appellant’s writ of error coram nobis should have been treated as a PCRA petition because his claim was “cognizable under the PCRA” and the “PCRA is the only method of obtaining collateral review.” Commonwealth v. Descardes, 136 A.3d 493, 503 (Pa. 2016) (petition for writ of error coram nobis treated as a PCRA petition where claims asserted were cognizable under the PCRA); see also 42 Pa.C.S.A § 9543(a)(2)(ii) ____________________________________________ following charges: persons not to own or possess a firearm, possession of a controlled substance, and receiving stolen property. As part of his negotiated plea deal, the Commonwealth withdrew the PWID charge. Therefore, Appellant’s assertion as phrased in his June 8, 2017 submission is erroneous. -3- J-S08008-20 (recognizing ineffective assistance of counsel as grounds for collateral relief under the PCRA). Accordingly, we “review a denial of PCRA relief to determine whether the PCRA court’s findings are supported by the record and free from legal error.” Commonwealth v. Albrecht, 994 A.2d 1091, 1093 (Pa. 2010). Before reaching the merits of Appellant’s claims, we must address the timeliness of this appeal. The timeliness of an appeal concerns our appellate jurisdiction, which we may raise sua sponte. Commonwealth v. Andre, 17 A.3d 951, 957–958 (Pa. Super. 2011). To lodge a timely appeal from a final order, “the notice . . . shall be filed within 30 days after the entry of the order from which the appeal is taken.” Pa.R.A.P. 903(a). Pursuant to Pa.R.A.P. 1701(b)(3), the time for filing an appeal may be tolled if the court enters an order “expressly grant[ing] reconsideration” within the 30-day period. Id. Simply filing a motion for reconsideration, however, “does not toll the 30-day period for a PCRA dismissal.” Commonwealth v. Collins, 2019 WL 3205786, at *1 (Pa. Super. July 16, 2019) (unpublished memorandum); see also Commonwealth v. Moir, 766 A.2d 1253, 1254 (Pa. Super. 2000). Herein, the PCRA court denied Appellant’s PCRA petition on July 24, 2017, and on August 25, 2017, Appellant filed a motion for reconsideration. The court, however, never expressly granted Appellant’s motion. As such, the 30-day appeal period was not tolled and Appellant needed to file his notice of appeal by August 23, 2017. Appellant filed his notice of appeal on March 25, 2019, 609 days after entry of the July 24, 2017 order and 579 days after the -4- J-S08008-20

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*(-3 - -5). Let x = o + -2. What is the remainder when x is divided by 10? 3 Let b = -41 + 43. Let z be (b + -2)/2 - 13. Let x = z + 18. What is the remainder when 28 is divided by x? 3 Let n = -7405 - -7527. What is the remainder when 14881 is divided by n? 119 Suppose -752*v = -718*v - 1428. What is the remainder when v is divided by 40? 2 Let d = -361 + 389. Let x(c) = -3*c + 3. Let i be x(4). What is the remainder when d is divided by 0 - (1 - (0 - i))? 4 Let g(n) be the first derivative of -n**4/4 - 5*n**3/3 - 6*n**2 + n - 210. Calculate the remainder when 218 is divided by g(-5). 35 Let w(p) be the first derivative of -8*p**2 - 2*p + 30. Let x be w(1). Calculate the remainder when 0 - (1341/x + (-2)/4) is divided by 13. 10 Let k(r) = -42*r**3 - 54*r**2 - 5*r - 5. Calculate the remainder when 1123 is divided by k(-2). 123 Suppose 0 = -2*u - p + 556, 3*p - 5*p = u - 278. Calculate the remainder when 904 is divided by u. 70 Calculate the remainder when 4*70236/(-120)*15/(-9) is divided by 64. 62 What is the remainder when (-277160)/(-1312) + (-3)/(-4) is divided by 59? 35 Suppose 27*q + 247 = 80*q - 40*q. Calculate the remainder when 1964 is divided by q. 7 Suppose -29*g + 250 = 18. Suppose -g*x - 21*x = -667. Suppose -6*k + 4*k = -82. Calculate the remainder when k is divided by xFOR IMMEDIATE RELEASE March 31, 2020 CONTACT: Hannah McKinnon, hannah [at] priceofoil.org Collin Rees, collin [at] priceofoil.org Oil Change International response to Keystone XL subsidy announcement from Alberta Today, the Government of Alberta announced that it would support TC Energy’s Keystone XL oil pipeline with a direct investment of more than USD 1 billion and a further USD 4.2 billion loan guarantee. In response, experts at Oil Change International released the following statements: Hannah McKinnon, Energy Transitions & Futures Director: “Never has there been a more critical moment to support health, workers, and communities. Instead, the Alberta Government is diverting limited and desperately needed public money to Big Oil in the latest misplaced attempt to revive the Keystone XL pipeline and prop up a sector that has no role in a more resilient, safer climate future. “The Keystone XL pipeline was a non-starter a decade ago and it remains one today. With trillions of dollars at play globally in relief and recovery, we have an unprecedented chance to invest in the future, not the past. Unfortunately, the Alberta Government is still refusing to see the writing on the wall, a failure that comes at a huge cost to Albertans in this crisis moment.” Collin Rees, Senior U.S. Campaigner: “This desperate attempt by Alberta’s Government to push through the failing Keystone XL pipeline during a global pandemic is beyond the pale. We need billions of public dollars invested directly in vulnerable communities dying from COVID-19, not spent propping up massive oil companies and unneeded projects that would trample Indigenous rights and exacerbate the climate crisis. “This huge giveaway of public money to fossil fuel executives coming just days after Jason Kenney’s government laid off more than 20,000 educational workers across Alberta says more about where his priorities lie than we ever could. The Indigenous communities, farmers, and ranchers along the Keystone XL route will continue to fiercely resist, and this pipeline will never be built.” ### Notes: This weekend, Premier Jason Kenney’s Alberta Government drastically cut educational funding across the province, laying off more than 20,000 Albertan workers: https://www.cbc.ca/news/canada/edmonton/funding-reduction-alberta-k-12-covid-1.5513803 Oil Change International response to recent Export Development Canada changes: http://priceofoil.org/2020/03/28/oil-change-international-response-to-export-development-canada-changes-in-the-emergency-response-act/ Report detailing more than CAD 10 billion in fossil fuel finance from Export Development Canada: http://priceofoil.org/2018/11/22/risking-it-all-export-development-canada/ Report detailing Canada’s billions in fossil fuel subsidies: http://priceofoil.org/2016/11/16/canadas-fossil-fuel-subsidies/This Wednesday, I attended a workshop at the University of Michigan Museum of Art on a painting by Benjamin West: During the workshop, I noted different strategies employed by the docents and speakers to “teach” us about the art and recorded strategies for using art – as well as general teaching strategies - in the English and/or Social Studies classroom: 1) If you’re using a painting to illustrate a historic event you’re studying or to give historic context to a work of literature you’re teaching, project the image of the artwork and give a mini-lecture on the history behind the work. Also show a map of the relevant region and talk discuss the region’s relationship with the rest of the world and relevant cultural information. 2) Structure lectures in a Q&A format. State the question and then answer it. 3) As an introduction to a historic events, show students a historic painting that illustrates the event and talk about the events that led up to the one depicted in the artwork. Instead of telling students the details of the event, have them make predictions about what’s going to happen based on the artwork and the info you’ve given them on the events leading up to the topic you’re studying. Then, teach the actual details of the event. Afterwards, have students compare what actually happened to their predictions. Also show the artwork again and have students identify what they’ve learned by pointing to particular things in the artwork. 4) To hook students’ interest before studying a particular work, project it alongside a quote that speaks to its legacy or makes a provocative statement about it. You can project the text of the quote or introduce a lecture by speaking the quote aloud. 5) The exhibit consisted of several artworks – portraits, maps, writings, etc – centered on a single topic: General Wolf. Also posted in the exhibit were large quotes printed on the wall. These could be quotes from soldiers’ diaries, quotes from historians, quotes from artists who depicted the subject, etc. I recommend giving students a “gallery” experience regarding a particular subject by presenting them with a variety of works, including quotes or literary passages, that all comment on a particular event. Students can then synthesize the information to develop a comprehensive understanding of the subject. They’ll notice patterns but also contradictions which will raise questions and drive their thinking deeper. 6) When looking at portraits, consider if they’re “vignettes” or more complex narratives. When I say vignette, I mean a portrait that captures a single, focused moment. There’s one thing going on that you’re meant to focus on. Other portraits have various things going on in the image simultaneously. PROJECT IDEA: If you’re having students create a self-portrait or portrait of a character to show their understanding of identity, motives, emotion, thoughts, and goals, consider having them integrate multiple images into a composite portrait. It’ll be interesting to deconstruct and then reconstruct t in a character analysis. 7) When studying the historic facts alongside an artwork that portrays the event, look for accuracies and inaccuracies between the history and the art-story. You could also teach vocabulary alongside this - things like contradiction, paradox, objective vs. subjective, portrayal, etc. 8) Look at multiple works that tell varying narratives about a particular event. You could study tone and consider why the artists portrayed the event differently. You can also talk about artists and artists in terms of reliability. How do we know what’s true? Can fiction make a true statement? How do we piece together contradictory information to draw the most accurate conclusion? 9) Why do authors/artists make changes, additions, and deletions to their characterization of something? 10) The intersection of portrait and idealization. Are realistic works like landscapes and portraits more than representations of something? In what ways are they “re-presentations”, or produced and constructed and skewed, representations of something? Why do this? 11) Historic paintings are often a combination of depicting anatomy, architecture, documenting the landscape, etc. 12) Instead of showing the artwork in its entirety, crop a few images out of it, showing them to students one-at-a-time. Have students analyze each image on its own and have them try to piece together what they think the larger image looks like and is about. Then,

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people, see fit to choose me as their next prime minister," "I will see to it that 1972 will be the beginning of real equality and health and education for all young Australians." "Will you be mounting your production in London?" "I'm not sure." "I haven't thought that..." "My daughter left me before the storm." "Did I tell you that, Lotte?" "She never understood that choosing between the sublime and the sensible often comes at a cost." "Let us not dwell on my children." "I've had enough disenchantment for one day." "Are we wearing our dress?" "We are, Mrs Hunter." "Our baubles?" "But of course." "Then, please, dear Mrs Lippmann, enchant me." "Tonight is unquestionably a night for..." "The tingle tangle." "Faster." "Faster!" "Faster!" "Come over." "Come on." "Oh, no." "Oh, no." "No, b-back." "Back!" "Oh, that's good." "Oh!" "It's coming." "That's good." "That's good." "No, it's not." "Kiss me." "Touch me." "Touch me." "Oh, yeah!" "Ah!" "I'm sorry." "I'm a dead loss." "No." "That's alright." "Here we go." "Ah, ah, ah." "Darling." "What a homecoming." "Darling!" "Darling." "How I've waited." "I thought the lambs were more important than me." "Why have you made me wait?" "Plane delay." "In ghastly Bangkok, of all places." "And then I needed to rest, to be at my best for you, Mother." "You were never, shall I say, deceitful but often devious." "How's poor old Dorothy?" "Dorothy is still poor old Dorothy." "Full of the wrongs done her." "Ah, you're wearing my Ethiopian ring." "The only thing you ever gave me in half a lifetime of absence." "Where's my kiss?" "Look at you." "Oh!" "You'll end up crippled like me." "All ailments are hereditary." "Thank you." "So are moral flaws." "Must I compete already for my son's attentions?" "Go." "You should be staying here, in your old room." "I've booked a room at the Onslow." "I didn't want to put anybody to any trouble." "But I have Mrs Lippmann to care for us." "Poor old Lotte." "The only one in her family to escape the German horrors." "When the Nazis come to town the cabaret dies." "How long since your last employment?" "I have several irons in the fire in the West End, one especially exciting." "Don't expect me to come and see it." "I stopped expecting that long ago, Mother." "Oh, darling." "You know I never come to see you because if you weren't any good, it would break my heart." "But I just might be very good." "They printed the reviews of your "King Lear" in the Sydney papers." "They thought enough of me over there to give me a knighthood." "But that was before your "King Lear"." "Hm." "How's your love life?" "Oh, brilliant, darling." "How's yours?" "He's taller than I thought." "What?" "!" "And sexy too." "He's definitely better in real life." "He is distinguished, certainly." "Yeah." "I could have him." "Save the leftovers for me." "What leftovers?" "Well, I'll be off, then." "Ooh!" "But no." "Mrs Hunter will be upset if I am not feeding you up." "I have to watch my figure." "Well, you've got no worries." "You're in great shape." "Sir." "Please." "Well, just a smidge." "Thank you." "Hm." "Mrs Lippmann is a performer too, you know." "Ah!" "Like yourself." "At a different height, it goes without saying." "You the great artist, me just a dizzy fizzer." "But theatre was necessary for us both, yes?" "Yes." "When we walked out through the lights, we forgot love." "Pain." "Murder..." "For me, performance is probably much like... nursing." "We have to feel the situation, but you can't drown in it." "Oh, no." "So this is for me and whose army?" "I enjoy to feed everybody." "Now, can someone tell me, who's the ancient lilac fairy upstairs masquerading as my mother?" "The creation of another being from one's own body, a complete and decent human being, a fearsome labour for a mother..." "and an actor." "Well, therein lies the play." "I'm not horribly late, am I?" "I expect I am." "Not at all, Princess." "Oh, Dorothy, please." "Oh, thank you." "I must admit, my wife and I privately still call you by that." "How is she?" "I love Lal." "Very well, thank you." "Thank you." "You, um, comfortable at the club?" "Oh, yes, thank you." "I'm there by invitation, you know." "That's very considerate of them." "Well, my brother's late, at least." "Sorry, ladies, I don't have a pen." "No, I have a pen, but..." "I'm sorry, I don't have a proper book." "Would a tissue be alright?" "Fine." "And your name is?" "Lurline." "Lurline." "Lurline." "Skinner." "Is that our country house, Cudgerie?" "Oh!" "There's Daddy." "Yeah." "You and my father were close friends, weren't you?" "We shared an interest in clocks." "I'm afraid nobody, none of us, loved him as he deserved." "Good old Dorothy!" "Oh!" "Oh!" "Basil." "Oh!" "You have improved quite a bit, darling." "Oh." "For God's sake, Dottie." "After all this time, allow me the pleasure of your eyes for a moment or two." "Don't you think we should get on with things?" "Mr Wyburd might have another appointment." "Good old Wyburd." "Mrs Hunter gathered from your letters a certain desire to discuss what might be best for her." "I've, uh, taken the liberty of preparing this." "Hm." "Mmm." "Good." "Mmm." "Yeah, well, you've..." "done a wonderful job." " So..." " Um..." "Well, Basil." "Oh, yes." "Well, um..." "If I may." "What we have to decide is whether a person who's reached my mother's - sorry, our mother's - age derives happiness and comfort from her half-life in proportion to the elaborate and..." "shockingly expensive machinery needed to maintain it." "I mean, surely the needs of old people when their minds are uh, compromised must be... simple." "Mrs Hunter's mind may wander at times, but it always appears to be searching after subtleties." "I'd say she's still the most complex woman I know." "And she enjoys her life." "She's giving away jewellery." "I mean, that Flora girl, how long has she been there?" "Is she the attractive one?" "She's wearing Mother's watch." "Are you aware that she keeps a full-time gardener and a part-time one?" "I believe that Mrs Hunter would rather die than have her way of life dictated to her." "To talk sense into her wouldn't be dictating." "Mmm." "You could do that, couldn't you, dear old Wyburd?" "Your mother asked me to give you these small gifts." "Oh." "Thank you." "Hm." "Let it appear thus." "A minimum of scenery and props." "Nothing to interfere with the inner life of the characters." "It must be architecturally and emotionally sparse." "This could restore one's faith in theatre." "You alright, Mrs H?" "Thanks for the lend of your strong arms, Col." "You're a very strong man for a chemist." "It's a couple of years before I'm a full chemist yet, Mrs Hunter." "Just downstairs on the right, in the living room." "Do you want me to come and pick you up after I close up the shop?" "No." "Well, you'll need someone to get her back up the stairs." "It's alright." "Her son can do that." "Perfect, darling." "Another day, another hairdo." "You look splendid." "Sorry I'm late." "Lilies." "I adore lilies." "Lovely." "Thank you." "Bless you, darling, for your generosity." "You've always had impeccable timing." "Don't spend it all at once." "No." "Yum." "Tea for two?" "Of course." "Gentlemen prefer martinis." "Not with cake." "I'm wearing the white today." "Dorothy!" "Edvard!" "Is she awake or asleep?" "Somewhere in between." "Edvard!" "So, we go for swim?" "No, not me." "I..." "I

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be nice?" "Oh, I don't know. I always got the impression that he rubbed you the wrong way." Except for those hot kisses last night, he'd never rubbed her in any way. That was the problem. Funny how it had taken Camille years to figure that out. In the most innocent tone she could manage, she said, "I can't imagine where you got that idea." "Well, you practically laughed with glee when he and Renee divorced." "That's because she was horrible for him," Camille reasoned. "And Matthew should have realized she was a horrible fit for him." "Uh-huh. You mean like you should've seen how Graham was all wrong for you?" Maureen asked smugly. "Exactly," Camille retorted, then sighed as images of last night whirled through her mind. "Actually, Mom, I'm—enjoying Matthew. He's a lot different than the way I remembered." "Different? In what way?" Instead of a spindly young guy, who'd been totally unsure of himself, Matthew had turned into a sexy hunk of confident man, she thought. To her mother, she said, "Well, he was always sort of quiet. That hasn't changed much. But I'm learning he has a bit of a sense of humor and he's a good listener." Pausing, she chuckled. "Or he might just be letting me talk so he won't have to." Several seconds of silence passed and just when Camille was wondering what her mother was thinking, Maureen said, "I'm glad you're enjoying him, honey. I don't have to tell you how much Matthew means to the family. And he's—well, I'm not sure he's ever gotten over his difficult childhood." The things Matthew had told her about his family, or lack of one, were still haunting Camille, and she wondered how he'd grown up to be such a responsible man. If asked, he'd probably give all the credit to Joel, but that wouldn't be entirely right. He'd been a hardworking, trustworthy man when he'd first come to Three Rivers. Joel had simply nourished the goodness in him. Camille said, "Last night he mentioned having a sister. I wasn't aware that he had a sibling. I've never heard any of you mention her. Does he ever see her?" "Not often. The last time was right after you left for Red Bluff. Blake purchased a bull over in California and he sent Matthew to haul him home. The trip gave Matthew a chance to stop by Claire's place." "I see." Deciding she'd better change the subject before her mother started to think her interest in Matthew was a bit excessive, she said, "I guess you're going to have a Halloween party. Do all the kids have their costumes yet?" Maureen chuckled. "Abagail and Andrew are going to be cats with tails and whiskers. That's the most important thing, of course." "How cute," Camille said with a laugh. "What about Nick and Hannah? They probably think they're too old to party with the babies." "Not in the least. Nick and Hannah love being big bosses of their little siblings. And anyway, Viv has promised to take those two to a party on the res that's just for teens and tweens." Missing out on spending time with her nieces and nephews was the one regret Camille often had about making her home here on Red Bluff. On the other hand, it would be difficult living back on Three Rivers and her being the only Hollister sibling without a spouse or a child. It was hard enough to deal with living two hundred fifty miles away. Single and childless at the age of twenty-eight was not the way Camille had envisioned or hoped her life would be. But it had turned out that way and now she was determined not to lament the situation, but embrace her independence. As far as she was concerned that was far better than nursing a broken heart. "Have you seen Emily-Ann lately?" Camille asked. "No. But Katherine sees her regularly. She misses you. I know that much." Emily-Ann had been Camille's best friend since their days in grade school. She ran Conchita's, a tiny coffee shop in Wickenburg that served bakery treats and specialty coffees. "I miss her, too. I'm hoping she can come down for a visit soon." "Emily-Ann isn't exactly flush with money," Maureen pointed out. "I doubt she can afford to stay away from her job for more than a day or two." Camille's friend was dependable and hard working. She'd be great as a waitress for the diner. But in spite of the struggles and stigma she'd suffered through, Emily-Ann would never move away from Wickenburg. It was her home. "I'd make sure she wouldn't have to spend a dime, Mom." "I expected you to say that. So why don't you invite her down for Thanksgiving?" Maureen suggested. "You could take her to Tucson and do some Christmas shopping." "That's a nice idea." "Good. I—" Her mother's words were suddenly interrupted by the sound of distant voices. Camille asked, "Mom, do you need to get off the phone?" "Uh—yes, I'm afraid I do. Blake needs me for something. Love you. And be sure and take extra good care of Matthew." "Yes—I will. And I love you, too." Camille punched the phone to disconnect the call, then rose from the lounge chair. As she walked back to the house, her mother's words played over in her mind. _Take extra good care of Matthew._ What would Maureen think if she knew just how much Camille wanted to care for Matthew? Would she think her daughter was reaching for something she could never have? Last night, when he'd kissed her, she'd thought he was finally going to lower the barriers he'd erected between them. For those few brief moments he'd held nothing back and she'd met the reckless desperation of his lips with the same hungry need. She'd never wanted any man to make love to her as much as she'd wanted Matthew at that moment. But he'd pulled away and implied that their kisses had been a mistake. Could he be right? As Camille went to her bedroom and changed out of her church clothes, the question continued to circle through her thoughts. For the past two years she'd done a lot of growing, and now it was easy to see where and why she'd made the mistake in getting engaged to Graham. Yes, she'd learned her lesson. But what about now? What about Matthew? Oh Lord, never in her wildest dreams had she thought his time here at Red Bluff would mean anything more than having a visitor in the house. She'd honestly expected him to be sullen and curt and she'd planned to ignore him as best she could. How laughable was that? she asked herself as she pulled on jeans and a thin pink shirt. The moment she'd looked across the threshold at Matthew's tired face, something had smacked her right between the breasts. And try as she might, she couldn't get rid of the feeling. But he wasn't down here for romance, she reasoned with herself. Besides, he'd been divorced and single for nearly ten years. The man clearly had no desire to marry again. So what good would it do her to have a brief affair with him? No good. Matthew was right and she knew it. But for some reason her heart wasn't listening to reason. Chapter Five After searching the southernmost range of the ranch for the entire day, Matthew and the small crew of cowhands helping him came up with six of the missing ten steers. Although the men were disappointed that they'd not found the last four, Matthew was pleased with the effort. They could've just as easily ended up with zilch for the day. "When are we going to vaccinate and tag the new cattle, Matthew?" Pate asked, as he steered the double-seated work truck coupled to a long stock trailer over the rough ground. Slumped in the passenger seat, Matthew was attempting to grab a bit of shut-eye during the drive back to the ranch yard, but with Pate hitting every rock in the old roadbed, his head was banging around like a punching bag. Biting back a tired groan, he straightened on the worn leather seat and gazed out the window at the desert hills covered with purple twilight. Red Bluff was an enchanting place and not just because Camille was here, he decided. There were parts of the ranch that were incredibly green to be located in such a desert area. Then there were other parts that were full of high rocky bluffs and hundreds of tall saguaros with their arms reaching toward the wide, endless sky. He wondered how much, if any, of this land Camille ever seen. Did any of it truly matter to her? Or did she only care about the house and having her privacy? Last night, when she'd talked about trying to help out with the ranching chores at Three Rivers, he'd gotten the impression that she'd wanted to be as much of a cowgirl as her mother and sister, but she lacked the confidence to

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deeply, almost holding his breath as my mother handed this tiny infant into his clumsy hands. Inside were my sister and brother, with my Aunt Cheryl and my mother’s parents. We lived on Northwood for six months before moving to Athens, and as I stroll by I wonder what my life would have been like if we stayed. “No doubt, I wouldn’t be working in a record store, getting drunk off my ass” I think as I quicken my pace. Just past Patterson Avenue, just two blocks from home, I spy Dow’s on High, I need to pee. The campus area reeks of urine from too many drunken frat guys and out-of-campus visitors relieving themselves on the sidewalks, alleys and doorways of High Street and neighboring streets, it is unfathomable that these are the future leaders of the new world. I made a vow not to do this unless it was absolutely necessary, I do a slow motion backwards count of how many drinks I have had, “let’s see, at least four at work but I had pizza and I started at four. Three beers and a shot at Larry’s, that’s only like um, seven and half over five hours. I’m fine.” The alcohol has settled in my knees and around my ears, I can feel it but I am thinking clearly. I don’t want to overshoot it, so, I manage the intake well. this has been done countless times before, I open the door to Dow’s, it isn’t very busy. “I’ll have a Bud, be back in a moment.” The bar is small, with a thin walking space next to the bar and a jukebox that almost hides the men’s room, just to the left of the men’s room is an underutilized room that has a haber-dash of beer signs and posters left over from the nineteen eighties, an old Cleveland Browns poster complete with a schedule from 1990 dangles from the far wall. The season is only half-filled out, by week nine, after a drubbing by the Buffalo Bills that left the morose team, 2-7, even the hardcore owner of Dow’s had given up. And he was an ex-Brown and played for Ohio State. The poster has started to curl at the end, a seldom used pool table sits under a thin hanging light with only three of the four bulbs working, there are stacks of beer protruding from behind an area that was once a kitchen. It would be easy to make off with several cases of beers out the back door which is at the end of a long hallway jutting off from the far wall. That would not happen in a place like Dow’s though, which is the loneliest dive/sports bar on this stretch of High Street. It’s a good place to drink, with polite bartenders who eye us carefully but after several visits accept us. The jukebox sucks, filled with the likes of Journey, Bon-Jovi and Heart, and most times when there isn’t a Brown’s game on it is playing, “Don’t Stop Believing” and “Barracuda” for the four thousandth time. I wait outside the men’s room, although there are only a handful of patrons in the bar, one of them is taking a leak. Behind me sits a small table, with a crock-pot filled with homemade Barb-queue, and a large spoon ready to fill up a thin white roll that is housed in a yellow and clear plastic bag. A stack of styrophom plates and a bag of rippled chips sits on the table. There is a football game flickering on the television but it is not the beloved Browns. While waiting to pee, I shake my head at the juke book, where Billy Idol is bellowing away. Dick’s Den is one of the oldest bars around the campus area, with multiple nights of live jazz being played, although Dick’s was no piano bar, a tiny almost platform stage wedged between a the doorway to the most cramped area laid out for a pool table, just to the left of the doorway, shoved into a corner as if straddling a cliff sat a Terminator II pinball machine. If you played the game a bit rough, full with fits, bumps and lunges you may well make the jukebox, filled with Billie Holiday, Duke Ellington and Miles Davis, skip. Below the stage were a handful of tables, where the drinks would jockey for space much like the musicians on the stage. The bar staff was older than the staff at Larry’s, the Blue Danube and Staches, with many left over from the High Street debauchery of the 1960’s and 70’s. It was, in a way the post-doc equivalent of a bar compared to the graduate student manner of Larry’s. I was usually frustrated with doorman at Dick’s, due to the explosion of college clientele during their carnival/riotous nights of quarter beer nights during the early nineties. While, I’m sure the loved the business they made quick changes to the flood of frat types on the Wednesday nights of quarter beer nights, the first upping it to .50 beer nights and cracking down on carding people. I took some umbrage at being carded every time I went into Dick’s, mostly because I drank there at least once a week and also for the fact that I had assumed I had long-ago cemented my credentials as a High Street veteran. Dick’s was busy that night because, sure enough, it was .50 beer night and as I stuck my ID back into my back pocket, I eyed Jenny sitting at the bar with a tall bottle of Rolling Rock in front of her. “Hey,” I said as I saddled up next to her, raising my finger to the bartender and mouthing the words, Budweiser to him. He was a Used Kids regular, prone to buying Lucinda Williams, Jimmie Dale Gilmore as well as jazz titles, he nodded and smiled, silently placing a beer in front of me he stuck his hand up, signaling I didn’t need to pay. I flipped him $2 for a tip and nodded my thanks. Jenny smirked at me, “you come here often I guess?” Looking sideways at her, as I lifted the bottle, now neck empty, “not too much, really, maybe once a week. He comes to the shop a lot, I usually give him a deal. The secret to successful drinking is to know how to treat your bartender, in or out of the bar. Smiling, and shaking her head, “I see that.” After a few formalities she cut to the chase, “hey, I think it’s cool that you asked me to join you, I could have paid for a ticket but you know, graduate school money doesn’t go very far. So, that was nice. But I need to let you know I have a boyfriend, Kevin, and he lives in Philadelphia. I just don’t want you to think that, um, I don’t know…..”, she looked skywards, “now, I feel stupid.” Thinking to myself, “only Jerry thought this was a date”, I smiled, “I didn’t think of anything more than just getting you in, really, I didn’t think this was a date or anything. I’m not good at that sort of thing anyway.” In some way I was relieved, shirking from any sort of romantic investment was easy for me, a great deal of the people I spent time with were woman, almost all on a platonic level. “Whew, I was worried you might be upset with me,” she replied, almost to herself, and it was obvious a burden was taken off her shoulders. “nope, not at all.” I stuck my hand up for two more beers, pointing to her half empty bottle and my empty one. “Don’t you think we should go? It’s like 10:30 and I think the ticket said 9:30. I wanna see your friend’s band, Gaunt.” “it’s alright, shows here start late, and besides there is another band playing first, there are always three bands. I think their called Swivel-Arm Battlegrip, Gaunt will go on in about twenty minutes and they’ll play a short set because Jerry is nervous about playing with Unrest. He loves them so he won’t play too long.” Staches was half-full, Unrest had just put out the finest record of their career, “Imperial F.f.r.r.” and chimy, ringing piece of guitar pop, the was one of the most catchy records of the year. They had played Staches the year before, again with Gaunt, and were lack-luster as was the turnout for the show. It was a decent crowd for a Wednesday night, and when we entered, I got three beers from the bar, two Budweiser’s for me and a Rolling Rock for Jenny. “you don’t have to buy me any drinks, in fact I probably shouldn’t drink very much more, I have class tomorrow.” “It’s ok, I don’t mind.” I motioned to the stage, where Jerry was just getting ready to plug his guitar in, Gaunt had jelled into quite a live band by this point, having released three records on Thrill Jockey (“Whitey the Man”, “I Can See Your Mom From Here” and “Sob Story”) and doing several tours. Jovan Karcic was a welcome addition to the band, of Serbian descent, J

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1.408& 40& 10& 1.1& 0.3& 0.5& 33& 10&22.0& 0.3& 21.7& 0.3& 12.52& 0.01& 2049& 649 & 2005&634& 693& 217\ & 1.642& 73& 17& 1.6& 0.2& 0.5& 33& 5&21.4& 0.5& 20.7& 0.5& 12.11& 0.01& 1953& 622 & 1819&579& 651& 205\ & 4.850& 50& 21& 1.5& 0.5& 1.3& 29& 13&18.2& 0.2& 17.8& 0.1& 11.13& 0.01& 1413& 447 & 1316&431& 556& 175\ \ B1039$-$19&0.610& 50& 32&$-$2.7& 1.2& 0.7&$-$16& 1&20.4& 0.4& 20.3& 0.4& 11.62& 0.02& 658& 379& 650&374& 252& 130\ & 0.925& 67&126&$-$3.6& 3.2& 0.1&$-$14& 23&18.1& 0.3& 17.9& 0.3& 10.75& 0.03& 529& 299& 518&293& 224& 113\ & 1.408& 7&278&$-$2.8& 0.1& 3.4&$-$21& 1&18.0& 0.3& 17.9& 0.2& 10.14& 0.02& 525& 297& 519&293& 206& 102\ & 1.642& 71&189&$-$3.0& 3.0& 0.6&$-$18& 27&17.5& 0.4& 17.4& 0.4& 9.72& 0.03& 501& 282& 494&278& 194& 95\ \ B1737+13& 0.408& 84&109&$-$4.2& 0.8& 1.3&$-$14& 4&22.1& 0.6& 18.2& 0.8&& 359& 175& 252&122&\ & 0.610& 54& 20&$-$2.7& 0.7& 5.2&$-$17& 6&28.4& 1.5& 23.2& 0.4&& 581& 293& 397&193&\ & 0.910& 85& 58&$-$2.4& 0.2& 0.8&$-$24& 3&20.8& 0.3& 20.1& 0.3& 16.70&0.08& 322& 155& 302&145&216 &101\ & 1.408& 38& 23&$-$1.6& 0.8& 2.4&$-$22& 16&24.6& 0.6& 23.4& 0.3& 15.88&0.08& 443& 217& 401&195&198 &84\ & 1.642& 32& 58&$-$1.5& 2.3& 1.9&$-$21& 47&22.3& 0.3& 21.5& 0.3& 15.24&0.04& 367& 177& 345&166&184 &92\ \ B2045$-$16&0.408&111& 8&$-$1.5& 0.1& 0.5&$-$36& 3&19.4& 0.4& 19.2& 0.3& 12.88& 0.01& 810& 245& 792&239& 366& 110\ & 0.606&129& 2&$-$1.4& 0.1&31.1&$-$32& 1&22.7& 0.3& 22.3& 0.4& 12.09& 0.01& 1107& 334& 1066&322& 325& 97\ & 0.925&136& 53&$-$1.1& 1.1& 0.5&$-$36& 50&17.8& 0.4& 17.5& 0.4& 11.28& 0.02& 688& 209& 661& 200& 285& 86\ & 1.408&121& 6&$-$1.4& 0.1&10.2&$-$35& 3&19.6& 0.2& 19.3& 0.2& 10.84& 0.01& 829& 250& 805&242& 264& 80\ & 1.642& 99& 9&$-$1.7& 0.1& 4.3&$-$34& 2&18.8& 0.3& 18.5& 0.3& 10.71& 0.01& 763& 230& 737&222& 258& 78\ & 4.850& 92& 77&$-$2.4& 0.3& 2.5&$-$24& 4&14.7& 0.1& 14.3& 0.1& 10.11& 0.01& 471& 141& 445&134& 232& 70\ \ B2111+46& 0.610& 12& 10&$-$1.1& 1.0&15.8&$-$10& 13&88.7& 1.3& 86.2& 1.3& 59.07& 0.02& 683& 483& 647&456& 318& 215\ & 0.925& 13& 25&$-$1.4& 2.8& 3.1& $-$9& 25&82.1& 1.2& 79.1& 1.1& 55.29& 0.04& 591& 414& 551&384& 281& 189\ & 1.408& 13& 4&$-$1.4& 0.5&61.2& $-$9& 4&86.9& 1.9& 82.8& 1.8& 51.12& 0.02& 658& 464& 601&422& 243& 162\ & 1.642& 14& 28&$-$1.5& 3.0& 1.8& $-$9& 26&75.7& 0.5& 74.5& 0.4& 49.13& 0.06& 507& 352& 492&341& 225& 149\ & 4.850& 16& 42&$-$2.5& 6.6& 1.1& $-$6& 22&75.1& 0.6& 73.2& 0.6& 46.07& 0.03& 499& 346& 476&330& 200& 132\ [c@ l@r@[$\pm$]{} l@r@[$\pm$]{} l@r@[$\pm$]{} l@r@[$\pm$]{} l@ c@ c@ l@l]{} PSR B& Freq& & & & & ${\rm r_{\rm geo}^{\rm KG}}$& $\frac{(\rm r_{\rm geo}^{\rm OTS})}{(\rm r_{\rm delay}^{\rm BCW} (OTS))}$& $s$\ & (GHz)& & & & & (km)& & &\ B0301+19 & 0.408 & -0.48 & 0.54 & -1.18 & 0.24 & 139 & 157 & 341 & 70 & 567 & 0.87 & 0.66\ & 0.610 & 0.01 & 0.68 & -1.09 & 0.05 & -4 & 198 & 315 & 15 & 511 & -42.71 & $--$\ & 0.925 & 0.16 & 0.35 & -0.28 & 0.13 & -47 & 101 & 81 & 40 & 458 & -2.64 & $--$\ & 1.408 & -0.25 & 0.32 & -0.22 & 0.08 & 72 & 92 & 64 & 24 & 411 & 1.71 & 0.92\ & 1.642 & -0.50 & 0.88 & -0.68 & 0.66 & 146 & 254 & 197 & 192 & 395 & 0.55 & 0.52\ \ B0525+21 & 0.408 & 0.14 & 0.29 & 0.28 & 0.12 & -115 & 232 &-219 & 100 & 971 & -16.78 & $--$\ & 0.610 & -0.30 & 0.49 & -0.48 & 0.05 & 238 & 386 & 378 & 40 & 875 & 9.51 & 2.18\ & 0.925 & -0.21 & 0.36 & -0.28 & 0.08 & 165 & 286 & 224 & 68 & 785 & 11.52 & 2.40\ & 1.408 & 0.09 & 0.29 & 0.18 & 0.05 & -73 & 228 &-140 & 45 & 704 & -27.89 & $--$\ & 1.642 & 0.29 & 0.49 & -0.11 & 0.13 & -232 & 389 & 87 & 106 & 676 & -8.41 & $--$\ & 4.850 & -

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osphorus. The Greek communities lived along the seacoast in Kum Kapı, Samatya, and Fener. The headquarters of the Greek Orthodox patriarchate had been located in Fener since 1601. Members of the Greek Phanariot community carried out trade on the Black Sea, supplied dragomans (translators) to the Porte, and were appointed as princes of Moldavia and Wallachia. The Jewish community lived mainly in Balat and Ayvan Sarayı along the left bank of the Golden Horn in the eighteenth century (see chapter 2). The Armenians and the gypsies lived by the western wall in Sulu Kule and Samatya. The headquarters of the Armenian patriarchate was in Samatya. The Greek Orthodox and Armenian patriarchs were appointed by the sultan with extensive rights to administer the religious, legal, and cultural affairs of the Greek Orthodox and Armenian communities throughout the empire. The district of Istanbul contained the Topkapı Palace, the Hippodrome, the Friday mosque of Aya Sophia, and the Grand Bazaar. The Topkapı Palace complex, the private residence of the Ottoman dynasty and the center of government, stands on the first hill at the eastern tip (Saray Burnu) of the peninsula. Mehmed II built the palace over parts of the Great Byzantine Palace and the Acropolis in 1479. Enclosed by walls and divided into four courts, the Topkapı Palace contained public buildings where government business was conducted. The Topkapı Palace housed more than 6,000 people, of whom 500 were women, in the late eighteenth century, according to some accounts. The first court of the Topkapı Palace, also called the janissaries' court, contained military installations, the armory, the mint, and the Executioner's Fountain, where the executioner washed his hands after beheading high officials. The second court contained the Imperial Council, which functioned as a cabinet and a higher court of appeals (see chapter 8); the Inner Treasury; the Public Records Office; the grand vizier's office; and the palace kitchens (ten spacious rooms) that served food for several thousand people daily in addition to the poor. The executioner's room with a small prison was at the gate of the second court. The third court contained the Throne Room, where the sultan received officials, petitioners, and foreign ambassadors; the Pavilion of Holy Mantle, where the relics of Prophet Muhammad were preserved; the Privy Chamber; the Campaign Chamber; the Treasury Chamber; the palace school, the mosque of the janissary agha (head of the janissaries), and the library of Ahmed III. The imperial harem, the tulip garden of Ahmed III, and kiosks were located in the fourth court, the center of the private life of the sultan and his family, which overlooked the Sea of Marmara. The imperial harem was a vast building that occupied parts of the second and third courts and had more than three hundred rooms that housed several hundred female members of the dynasty, Ottoman princes, and their large staff headed by the chief black eunuch. The Topkapı Palace was used as the royal winter residence in the eighteenth century. Sultan Ahmed III commissioned a public fountain across the outer (Bab-i 'Ali) gate of the Topkapı Palace, added a library to the palace, and restored several buildings such as the Imperial Hall, the dining rooms (the fruit room), and the petition chamber. Persian decorative floral patterns and the French rococo style marked the new additions to the palace made by Ahmed III, Abdulhamid I, and Selim III in the eighteenth century. Adjacent to the Topkapı Palace was the Friday mosque of Aya Sophia and the former Byzantine Hippodrome. The Hippodrome was the ancient ceremonial center and the public square. Built by Emperor Setemius Severus in 1203, it was later extended and remodeled by Emperor Constantine the Great. It contained obelisks and columns, three of which still stand today; the Ibrahim Pasha Palace (grand vizier of Sultan Süleyman); and the mosque of Sultan Ahmed I (the Blue Mosque). Due to its function as a ceremonial center and location, many riots began in the Hippodrome in ancient (532 A.D.) and Ottoman times (see chapter 3). Under the Ottomans, it was renamed At Meydanı and continued to function as the ceremonial center. Processions, military drills, and public festivals celebrating the birth and circumcision of Ottoman princes and the birth and wedding of princesses took place in the Hippodrome. The janissary barracks (old and new rooms) and the Et Meydanı (meat square), where janissaries received their meat ration, were located on Divan Yolu and near the Hippodrome. The rebels used the Hippodrome as their base in 1703 and 1730 (see chapter 3). The commercial hub of the city was located very close to the Hippodrome and the Topkapı Palace. The Divan Yolu ( _via ignatia_ ) branched out in several directions from the Hippodrome and connected the area to the mercantile center of the city, the Grand Bazaar and its surrounding residential and commercial districts on the one side as well as the Egyptian Market and the port (Eminönü area) on the other side on the Golden Horn. Most of the 3,667 shops, numerous _hans_ (guest houses) and caravanserais, mosques, _medreses_ (Islamic seminaries), hospitals, and hospices were part of the Fatih, Bayezit, Süleymaniye, and Turhan sultan imperial pious and charitable ( _vakf_ ) foundations that were built during the sixteenth and seventeenth centuries in this district. In addition, the shipment, provisioning, and distribution of foodstuff and raw materials took place in the port area on the Golden Horn, where ships from all over the empire and the Mediterranean ports anchored. The Un Kapanı (flour depot) and Yemiş iskelesı (fruit scale) distributed flour to bakers at government-set prices and fruits citywide. In the marketplace various religious communities mingled together, carried out business, and belonged to the same guilds. As would be expected, this area also became a center of crime due to its commercial wealth and social diversity. The district of Istanbul was under stricter government control than the rest of city because the Topkapı Palace, the main residence of the sultan and his family, was located here. The administration of the city was under numerous officials: the grand vizier and his retinue of janissaries, the chief kadi (Islamic judge) of Istanbul, the chief inspector of markets, the chief of night police, the chief of day police, the _agha_ (commander) of janissaries in Istanbul, and the head of the palace guards (see chapter 7). #### THE EUROPEAN HUB: _GALATA_ Galata and Pera, on the opposite side of the Golden Horn from the district of Istanbul, were the hub of Western European trade and the center of diplomacy, finance, entertainment, and European residence in the early modern period. The walled town of Galata was a former Genoese colony, part of the Italian trading settlement on the Black Sea during Byzantine times. Galata had gained full autonomy because of its alliance with the Byzantine Empire against Venice during the restoration of Byzantine rule in 1261. It also had lent financial and military support to Byzantine forces during the Ottoman siege of March–April 1453. Some merchants had collaborated with the Ottoman army and handed the keys of the city to Mehmed II two days after the fall of Constantinople. Because of its timely surrender, Galata survived as a distinct city within a city under the Ottomans. The Ottoman sultan had rewarded the colony by granting capitulations to Genoa and partial autonomy to the town. The treaty provided the Genoese colony with religious and commercial freedom, security, and protection of property as well as exemption from extraordinary taxes, forced labor, and residents' service in the army. The colony also received the right to elect freely a person to represent its interests before the sultan. In return, the residents had to agree not to build new churches or ring their bells too loudly. These privileges were later granted to other Italian city-states and western European nations in the seventeenth and eighteenth centuries. Mehmed II divided the community in Galata into two groups, the non-Muslim Ottoman subjects who paid the poll tax and the subjects of Genoa who resided temporarily in Galata for commerce. The first group of non-Muslim subjects ( _zimmis_ ) included Greeks, Jews, Armenians, and some Genoese. The second group, defined as protected non-Ottoman merchants, received the freedom to trade in return for payment of customs dues. Both groups enjoyed distinct legal and religious autonomy. To establish Ottoman control over Galata, Mehmed II razed some of the land walls and kept the sea wall intact. However, the walls were restored by his son Sultan Bayezid II (1481–1512). The Galata tower (100 feet high and 50 feet in diameter) functioned as a fire-watch facility, a prison for indebted merchants and slaves, and a storage place. Galata was divided into three wards separated by inner walls that still stood in the seventeenth century. Its sea walls and inner walls had eleven outer gates and six inner gates opening into different neighborhoods. Galata inside the walls was a densely populated subdistrict with 200,000 non-Muslim and 64

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]; Liu *et al*., [@b66]), especially due to the destruction of habitats. Habitat heterogeneity and the intense productivity of such habitats, due to the higher availability of nutrients, could be possible explanations for peaks of species richness in suburban areas (McKinney, [@b71]). This also raises the issues of SAR dependence on scale, with consequences for LCA as characterization factors cannot be easily aggregated or disaggregated and applied to different scales. Other negative biodiversity impacts may also be observed, depending on the location of a disturbance or a forcing event. Bell ([@b10]), suggested that tropical rain forest birds tend to have more difficulty adapting to urban areas than do birds from other natural areas, such as temperate forests. de Baan *et al*. ([@b7]) devised an LCIA method using regionalized predictions of species recovery times from Curran *et al*. ([@b23]). This method broadly considers differentiated species responses. However, it should be noted that birds are a peculiar taxon due to their particularly large range of activity, and so it is unclear if the small marginal changes studied in LCA have a significant individual effect on bird species. The issue of how to reconcile scale in a method that addresses the marginal impacts of single-product production is thus far unresolved. Surrogate species: is there a unique choice for global assessments? ------------------------------------------------------------------- This discussion brings us to the species chosen as proxy or surrogate for the impact assessments, i.e. individual species used to represent the species richness of an area, or to predict the behavior of the entire environment when facing specific pressures. Such surrogate species are especially needed when detailed data, such as species distribution, are not sufficiently available (Lambeck, [@b64]; Hortal *et al*., [@b48]; Murphy *et al*., [@b77]). In conservation biology and environmental planning, biodiversity measures are essential to predict the status and changes of ecosystems. One of the biodiversity measurement options available is to use beta (*β*) diversity of surrogate species (Mazaris *et al*., [@b70]). According to Whittaker ([@b107]), alpha diversity is the species diversity of a community or habitat, beta diversity is the diversity between (neighboring) communities, and gamma diversity is the one diversity of a region (at a larger scale). Surrogacy can be of three types: cross-taxon, for which the species richness of one taxon is used to infer conclusions in other taxa; within-taxon, where a higher hierarchy ranking, i.e. genera, is used as surrogate; and environmental, for which parameters such as temperature are applied (Magurran, [@b68]). In LCIA, cross-taxon surrogacy is commonly used. Surrogacy is also used to indicate the anthropogenic influence on biodiversity, focusing on conservation, monitoring, and management actions, and in a political context, to direct attention to specific environmental aspects (Caro & O\'Doherty, [@b15]). Surrogate species are generally used due to the impossibility of measuring the overall biodiversity in a certain area, given the difficulty of collecting sufficient relevant data (Groves *et al*., [@b44]; Margules *et al*., [@b69]). Despite the apparent usefulness of surrogate species in impact assessment, no consensus exists on the use and consequences of the specific species chosen (Favreau *et al*., [@b38]). Some authors contend that the use of a surrogate, without verifying effective environmental responses, might compromise the effectiveness of the conservation aims (Andelman & Fagan, [@b2]; Cushman *et al*., [@b24]; Santi *et al*., [@b89]; Murphy *et al*., [@b77]), mainly because the cross-taxon surrogacy (i.e. of different taxa and species) may be poor (Kremen, [@b61]; Negi & Gadgil, [@b78]; Santi *et al*., [@b89]). Favreau *et al*. ([@b38]) argue that the use of surrogate species should be based on good knowledge of the affected species and how they interact with their environment. They might be a single or a group of species, chosen for various criteria such as body size, which is correlated with sensitivity to disturbances and lifetime (Caro & O\'Doherty, [@b15]). Most ecological processes are dependent on the scale and time (Wiens *et al*., [@b108]), and these two factors will also influence the ability of one species to reflect the behavior of others (Cushman *et al*., [@b24]). A meta-analysis of 138 different studies has shown that the use of different taxonomic groups for the assessment of land-use impacts might lead to different results, due to differences in sensitivity to land-use change (Gibson *et al*., [@b43]). It was found that mammals were less sensitive to disturbances in the landscape, while birds were shown to be particularly sensitive, especially to the land-use change from forest into agriculture. Within some groups, different taxonomic orders were found to be impacted differently. Santi *et al*. ([@b89]) investigated the degree of concordance among species richness and compositional patterns of different taxonomic groups, and found little cross-taxon congruence among most taxa. The choice of surrogate species is still debated and is barely discussed in current applications of land-use impact assessment in LCA, although it is recognized that different taxonomic groups should be used (de Baan *et al*., [@b6]; Souza *et al*., [@b95]). Vascular plants have been used in the assessment of the magnitude of land-use impacts (Müller-Wenk, [@b76]; Koellner, [@b54]; Weidema & Lindeijer, [@b106]; Vogtlaender *et al*., [@b104]; Michelsen, [@b73]; Schmidt, [@b92]), without further verification of the cross-taxon congruence/surrogacy of species diversity. Vascular plants have historically been used in land-use impact assessment in LCA mainly due to data availability (Schmidt, [@b92]) and the belief that they might correlate well with other species (Koellner, [@b54]; Weidema & Lindeijer, [@b106]; Vogtlaender *et al*., [@b104]), even though some authors argue that vascular plant species are an inappropriate surrogate indicator for biodiversity (Michelsen, [@b73]; Schmidt, [@b92]). Besides these issues, current discussions barely touch the importance of the choice of surrogate species. One complicating factor is that LCA requires models that can better represent a more globalized characterization of impacts, due to the global or cross-regional coverage of different production systems. Biodiversity dynamics: does it matter? -------------------------------------- In this section, we discuss the influence of ecological phenomena such as extinction debt and immigration credit on the assumptions of the impact assessment framework. We assess how compromising the disregard of related phenomena such as landscape interactions and species assemblage is to land-use impact assessment in LCA. The treatment of land interventions as being static, as in the current framework, is inadequate for reflecting changes in species diversity. In reality, these changes are not simply a result of the postponement of the recovery of land (occupation, LU), or a unique change in unit time (transformation, LUC), but the consequence of continuous anthropogenic activities and other environmental conditions, such as climate change. The land impacts that are considered do not reflect the cumulative effect of practices actually taking place. A fundamental issue with this model is that, for some land-use changes, extreme drops in the quality after land transformation are unrealistic if the metrics implemented refer to biodiversity (Kuussaari *et al*., [@b63]). With regard to species richness, and to use an extreme example, the conversion of land from natural vegetation to intensive agriculture will not instantaneously extinguish all local species and reduce the level of biodiversity as soon as the new land use takes effect. This concept of a delayed drop in quality (expressed in species diversity), and related temporary diversity surplus, is relevant to the issue because if losses are progressive and occupation is short enough, land-use impacts may be lower than expected. Conversely, if a patch of land is occupied over a relatively long period of time, the total impacts over time may lead to a threshold limit of biodiversity quality (Gibson *et al*., [@b43]) being met, leading to the collapse of the ecosystem. In this case, the difference between the initial and final steady-states should be higher. Documented examples show that extinction debts may persist for more than a century (Vellend *et al*., [@b103]; Cousins & Vanhoenacker, [@b20]), and this may lead to an underestimation of the potential impacts of land-use change on biodiversity. The ecological concepts of 'extinction debt' (Tilman *et al*., [@b96]) and 'immigration credit' (Jackson & Sax, [@b52]) were established to address the reasons why it is empirically observed that species levels decay at a slower rate than predicted by models. An immigration credit is the number of new species that immigrate to a certain area, following a disturbance, during a time elapsed (immigration lag) between the disturbing event and the establishment of the species (Jackson & Sax, [@b52]). The extinction debt is the time-delayed loss of species as a result of habitat destruction and fragmentation which may occur generations later in the undisturbed fragments that remained after destruction. A surplus in the number of species is observed, during a definite time (extinction lag), after a forcing event

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That’s debatable, but DC embraced it when the Batman titles underwent a soft relaunch after the year-long No Man’s Land crossover, with a redesign from Dave Johnson. It wasn’t just the costume, either. Johhnson also redesigned the GCPD uniforms with a really good retro style and even offered up a new design for the batarang, clearly going for a stripped-down approach that evoked The Animated Series. It’s a good-looking suit, and since printing had come quite a long way since 1964, the logo never blended into the costume the way it did back then. Plus, the treads on the boots are actually a good use of a seemingly inconsequential detail, in that they’re a subtle reminder of Batman’s lack of super-powers. The cape and cowl tell you he’s a superhero, but he’s also a guy who needs shoes with a little grip to them when he’s climbing up walls and chasing down crooks. 4: The Bat-chelor Party Batman costume (2018-Present) As you might’ve heard, Batman was supposed to get married in 2018, and then he didn’t. Then he got sad and decided that he was so sad that he could no longer wear purple and yellow, the colors of happiness. And so, Batman did what so many of us do when we’re depressed: He went back to whatever he was doing twenty years ago. In his case, that was a return of David Mazzucchelli’s Year One costume. It’s functionally the same as the “New Gotham” suit — including the boot treads — but the cape, cowl, trunks, and boots are all black instead of dark blue, which is weird. You’d think a guy that sad would be… feeling blue. It’s fine, but it definitely feels like a skittish step backwards after the Rebirth suit that it replaced. 3: The Zero Year Batman costume (2013-2014) When Scott Snyder and Greg Capullo got the job of giving Batman an updated origin story, they decided to pre-emptively counter the comparisons to Year One by just going in the opposite direction. Year One is a gritty, violent story set against the backdrop of the ‘80s crime wave. Zero Year is a neon-pink nightmare where Batman has to wrestle a lion because of the Riddler. It also features the return of the purple gloves which, like the lion-wrestling, is a bit of the Golden Age updated with a modern take. This suit is a weird one, but it’s a good take on mashing up the over-detailing of the New 52 with signature elements of Batmans’ past. Plus, the story also features Batman wearing a short-sleeved shirt and wrestler boots while doing dirtbike stunts, which doesn’t stick around long enough to be an official costume, but would make a solid runner-up for Best Batman. 2: The Rebirth Batman costume (2016 - 2018) After years of tooth-gritting seriousness, it was inevitable that the pendulum would swing back to embracing the bizarre, and the past ten years have been the weirdest Batman has seen since the ‘50s. Remember when Batman was Jim Gordon in a giant blue robot for a minute? Or when he died and came back to life because of magic metal and then got his memories back from a clone machine he keeps in his basement? Or when he had to fight his interdimensional murder-dad? That was last year. Greg Capullo’s Rebirth-era design reflects that. It has the heavy gauntlets and boots of the hilariously self-serious Arkham games, but they’re thrown in there with a bunch of delightfully weird touches. The utility belt is designed to look like fangs, the interior of the cape is a purple gradient for dramatic (and colorful) backdrops, and while it lacks the oval, the bat-symbol has a bright yellow outline to make it pop. It’s great. Batman is a person who does karate at homicidal clowns on a regular basis. He should look a little weird. 1: The “New Look” Batman costume (1964 - 1993) After it was refined a few times in the early years, Batman’s costume, much like Superman’s, would remain largely unchanged for the next 50 years. The keyword there, though, is “largely.” In 1964, Detective Comics #237 announced the “New Look” Batman, which basically amounted to exactly one change: Batman’s logo got a yellow oval around it. According to Michael Uslan, the producer of every modern Batman film, this was done to make the logo easier to trademark in advance of the Batman TV show, but there’s also a very practical artistic concern. Unlike Superman’s striking, immediately recognizable S — and the big blue 4s and spiders over at the newly minted competition — the black-on-grey logo was pretty easy to miss in the art. The oval made it pop, and tied it to the striking visual of the Bat-Signal, which had been around since 1942. There would be a few minor tweaks over the next couple of decades, but they’re all stylistic. Carmine Infantino, Jim Aparo, Neal Adams, Marshall Rogers and Alan Davis all drew the same suit; the only difference is how long they like their ears. The result was Batman’s best and most iconic costume, which stuck around for a full 30 years for a very good reason. It’s got a striking color scheme, and once the logo is tweaked to have the curved wings that fit in the oval, it’s one of the best pieces of iconography in comics. It’s also very adaptable to different styles and levels of brightness. The Batman: The Animated Series trick of drawing the cape, cowl, and trunks black and using the traditional blue for highlights, for example, is an extremely good interpretation and the reigning, defending Best Batman. In other words, these are Batman’s real clothes. Everything else is just something he wore that one time.Tag Archives: Orange This is a simple and delicious cake that uses the whole orange, which I find exciting each time I make it. I like it with flaked almonds as well as the almond meal for the texture they add. It is … Continue reading →Q: Python: draw multiple figures in separate windows (same data but with different X range) I wonder how to plot data in separate figures (not multiple figures in one window). The issue is that I want to visualize the data along different X range. For example: import numpy as np import pandas as pd import matplotlib matplotlib.use('TkAgg') import matplotlib.pyplot as plt X=np.linspace(0,100,num=1000) Y=X**2-X fig=plt.figure() plt.plot(X,Y) matplotlib.pyplot.xlim([0, 50]) plt.show() fig=plt.figure() plt.plot(X,Y) matplotlib.pyplot.xlim([50, 100]) plt.show() Here I get two separate figures. But I did the plt.plot() for the same data repeatedly. It can take time if the data is big. A: You can limit the range of data to plot, not only the viewing interval. To this end you may introduce a condition and filter the arrays to plot by that condition. import numpy as np import matplotlib matplotlib.use('TkAgg') import matplotlib.pyplot as plt X=np.linspace(0,100,num=1000) Y=X**2-X ranges = [[0, 50], [50, 100]] for r in ranges: cond = (X >= r[0]) & (X <= r[1]) fig=plt.figure() plt.plot(X[cond],Y[cond]) plt.xlim(r) plt.show() State gasoline tax to drop July 1 FILE - This Feb. 27, 2012, file photo shows gas prices at a Pittsburgh Exxon mini-mart. Exxon Mobil's fourth-quarter profit fell 16 percent as the company produced slightly less oil and gas and its refining business weakened, the company announced on Thursday, Jan. 30, 2014. (AP Photo/Gene J. Puskar, File) The Associated Press FILE - This Feb. 27, 2012, file photo shows gas prices at a Pittsburgh Exxon mini-mart. Exxon Mobil's fourth-quarter profit fell 16 percent as the company produced slightly less oil and gas and its refining business weakened, the company announced on Thursday, Jan. 30, 2014. (AP Photo/Gene J. Puskar, File) The state Board of Equalization voted 5-0 on Tuesday in Culver City to reduce the per-gallon excise tax on a gallon of regular gasoline to 36 cents per gallon, a 3.5 cent per gallon drop. The tax goes down July 1. The decision comes a year after the board voted to raise the tax by 3.5 cents per gallon. Still, Californians pay among the highest gas taxes in the nation, at about 68 cents per gallon through federal, state and

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/1*(-1)/2. Let g = m + f. Is g a multiple of 12? True Let d(n) = 5*n**2 + 55*n - 64. Is d(14) a multiple of 7? False Let b be (1 - (-1)/(-2))/(18/36). Let x be b/(5 - (-45)/(-10)). Suppose 2*y = 4*p - x*p + 406, 0 = y - 5*p - 199. Is 34 a factor of y? True Let y be 6 + -2 + (-4)/(-1). Suppose -y*q - 451 + 3907 = 0. Is q a multiple of 48? True Suppose t + 56 - 60 = 0. Suppose 0 = b - 4*a - 4 - 43, 4*b = t*a + 236. Is b a multiple of 22? False Suppose -344 = -16*w - 280. Let u be 1 - (-1 - (1 - 0)). Suppose -2*f - f = u*n - 252, -n + w*f = -104. Is n a multiple of 17? False Let o = 43 + -39. Let c(f) = -o - 2*f + 4*f**2 - 3*f**2 + 7. Is 22 a factor of c(10)? False Let z(f) = -249*f + 33. Let c be z(-3). Suppose 4*u + 2*p - 1042 = -0*p, -3*p + c = 3*u. Is 41 a factor of u? False Suppose q + 5*d = 18, 3*d = -2*q - 3 + 18. Does 27 divide (33/q)/(4 - (-55)/(-14))? False Let v = 4403 - 3438. Is v a multiple of 17? False Does 9 divide 539/(-147) - (-10514)/3? True Suppose 136 = 2*u - 2*s, 0 - 6 = 3*s. Suppose 0 = -c + u + 78. Is c a multiple of 16? True Suppose -6*n = -37 + 1. Is (-281)/(-3) + -2*n/18 a multiple of 15? False Suppose 5*h = o + 704, -4*h - 4*o + 511 = -57. Let m = 87 - h. Let i = -14 - m. Is 20 a factor of i? True Let z = 16514 - 5525. Does 27 divide z? True Let f(g) = 114*g - 1373. Is f(33) a multiple of 9? False Let d(h) = -4*h - 7 + 4*h + 9*h. Let z be d(2). Let m = 29 - z. Is 18 a factor of m? True Let f(c) = -37*c + 1. Let j be f(6). Let k = j + 427. Does 21 divide k? False Let c(q) = -q**2 + 17*q - 48. Let j be c(14). Let r = 118 - j. Is 12 a factor of r? False Let d be (0 + -1)/(12/(-50292)*3). Let m = d + -893. Is 36 a factor of m? True Suppose 4*c = -2*h + 9085 + 271, -5*c = 5*h - 23395. Suppose 15*q - h = 7*q. Is 45 a factor of q? True Let d be -3 + (426/4)/(14/28). Suppose 0*r + 2*r = 82. Suppose -r = q - d. Is 11 a factor of q? False Let p = 447 + 8473. Is p a multiple of 37? False Suppose 5*m + 4*q - 24960 = 0, 18*m - 3*q = 19*m - 4992. Is 32 a factor of m? True Suppose -l + 706 = 2*s + l, -25 = -5*l. Suppose s = k + 5*f - 3*f, -5*k + 1716 = 2*f. Is k a multiple of 6? True Suppose 20 = 2*h + 3*h. Suppose -h*y + 24 = 2*s - 80, -2 = 2*y. Is 18 a factor of s? True Is (1232/(-42) - 2)*(-21)/2 a multiple of 7? True Let n = 37 - 105. Let b = n - -141. Let w = b + -41. Is 8 a factor of w? True Suppose 3*i - 3172 = -4*q, 0 = 5*i + 4*q - 2101 - 3191. Suppose -490 = -10*v + i. Does 31 divide v? True Let i = -195 - -204. Suppose 0 = 5*v + 5*f - 3*f - i, -2*f - 15 = -3*v. Does 3 divide v? True Let g(j) = -5*j**3 - 2*j**2 - 2. Let x(q) = -q + 7. Let w be x(5). Suppose 6 = -3*r - 3*k, -k + 6 + 1 = -w*r. Does 17 divide g(r)? False Let w(i) = 6*i**2 + 48*i - 244. Does 34 divide w(-21)? True Let j = 2548 + 1086. Does 17 divide j? False Suppose 28*i = 151 + 58789. Is i a multiple of 54? False Let a = 185 + -291. Let n = -25 - a. Let f = -78 + n. Is f a multiple of 3? True Let t = 78 - -30. Let k = -102 + t. Suppose k*s - 45 = 207. Is s a multiple of 29? False Is 336/294 - 6/(-7) - -8586 a multiple of 9? False Suppose 0*p + 13624 = 30*p - 4*p. Is 4 a factor of p? True Suppose -5*r + 22 = -8. Let y = r - 0. Is 24 a factor of (-1070)/(-6) - y/(-9)? False Let r = 750 - 1512. Let m = -392 - r. Is 10 a factor of m? True Let u(w) = w**2 - 4*w + 5. Let g be u(5). Suppose 0 = -3*z + z + g. Suppose -o + 4 = 0, -8 = i + 2*i - z*o. Is 4 a factor of i? True Let q(m) = -33*m**2 + 67*m**2 - m - 31*m**2 - 17. Let h be q(7). Does 24 divide (0 + 3)*-1 + h? True Is ((-481962)/(-185))/(9/15) a multiple of 26? True Let u = -21008 + 22779. Is u a multiple of 23? True Let d be -2*1*85/(-34). Let t(y) = -30*y + 36. Let b(n) = 59*n - 73. Let x(q) = d*t(q) + 3*b(q). Is x(12) a multiple of 19? True Suppose -5*g = -25, 4*j + 3*g - 6 - 9 = 0. Suppose -r - 60 + 262 = j. Is 13 a factor of r? False Let s be 56/(-6)*(1290/(-35) - 12). Let m = s - 137. Is 7 a factor of m? False Let u(v) = -77 - 101 + 12 + 28*v. Is u(9) a multiple of 6? False Is (-25011)/(-3) + ((-16)/(-32))/((-2)/(-20)) a multiple of 194? True Let x(d) = -4933*d - 978. Is 26 a factor of x(-10)? False Let k be 9 - 1 - 27/(6 - -3). Suppose -3*d - 714 = -z - 0*d, -k*d = -3*z + 2130. Is 15 a factor of z? True Let b(j) = 14*j - 227. Let l be b(15). Let x(p) = -53*p + 19. Does 20 divide x(l)? True Let n = -91 - -157. Let c(q) = -2*q**3 - 67*q - 7*q**3 - q**2 + n*q + 29*q**3 + 2. Is 23 a factor of c(2)? False Suppose 3*f = 2*b - 393, 3*b - 318 - 297 = -4*f. Suppose 2*q - 87 - b = 0. Does 24 divide q? True Suppose 2*p = g + 9

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doubted that Socrates meant it, at least in its obvious sense: "Well then, I do not perceive what sort of thing you are saying is 'lawful,' or what sort 'just!'" (4.4.12–13). Socrates proceeded patiently to explain, through question and answer, that he was referring to the "lawful" in the obvious sense: the laws of any city. Hippias took this to mean what the citizens together set down in writing dictating what ought to be done and what ought not (since he speaks of the citizens and not of the multitude, or _d_ ē _mos_ , his definition of law covers all republican forms—aristocracy and "plutocracy" as much as democracy [see 4.6.12], and of course Sparta as much as Athens). Socrates accepted this, and then gained Hippias's agreement that the "lawful person" would be one partaking of civic life in accord with those written laws, and the "unlawful" would be one who violated them, and that the former would be doing just things, and the latter, unjust; and that "therefore, the lawful person is just, the unlawful unjust." Agreeing with all this (none of which entails the _identification_ of the just with the legal), Hippias expostulated: "But as for the laws (he said), oh Socrates!—how could one consider this a serious business, or obey these, when the very ones who establish them frequently reject and change them, upon scrutiny!?" (4.4.13–14). Precisely inasmuch as the sophist agreed that the law abiding is just, he could not take seriously either the just in this sense or the legal, as the true norms for a wise life (see the famous speech of Hippias in Plato's _Protagoras_ 337cff.). The rejoinder of Socrates was risibly sophistic, even demagogic—and therefore, as a chastening lesson for the famous sophist, most instructive. Asking (without allowing Hippias a chance to reply) if disparaging those who obey laws because the laws are often repealed is not equivalent to blaming those who fight well in war because peace later comes to pass, Socrates belligerently demanded: "So, are you also blaming those who with eager spirit take the field on behalf of their fatherlands in war!?" This outrageous imputation Hippias of course heatedly denied, swearing by Zeus (4.4.14). And Socrates then immediately launched into an uninterrupted speech. The monologue's first and shortest theme, expressed in two rhetorical questions, was the glory and the benefits that the city derives from having citizens obedient to law—as exemplified above all by Lycurgus's Sparta (4.4.15). The speech's second and somewhat lengthier theme was the public opinion of the Greek "cities" to the effect that that "the greatest good" is "concord" ( _homonoia_ ) among the citizens—meaning, as interpreted by "my thinking" (Socrates pointedly says here; cf. 4.6.14), concord that consists in obedience to the (city's) laws. "Without concord neither would a city be well governed nor a household nobly managed" (4.4.16). This is doubtless true; but does a household's concord _consist_ in obedience to the city's laws (see the _Oeconomicus_ )? At any rate, with the mention of the private household, Socrates segued to the third and much the longest theme of his monologue, the benefit to the "private individual" ( _idia_ ) of obedience to the laws, and the harm to the private individual of disobedience to the laws (4.4.17). Socrates listed, in the mode of anaphoric-rhetorical questions, no less than fourteen (or thirty-one, depending on how we count) private benefits, the first and foremost being avoidance of legal punishment (no small consideration for an itinerant foreigner like Hippias), and concluding with minimization of the number of one's enemies (the second half of the list is much preoccupied with the threat of and from one's enemies, and hence the need for friends and allies, in a state of war as well as peace; the previous praise of concord in lawfulness as a great civic good is thus followed by a spotlighting of the tenuousness of community; Socrates almost sounds like Hobbes). Socrates drew his personal conclusion: "I therefore [scil. because obedience to the law is beneficial in the ways stated, especially to private individuals], oh Hippias, show forth the lawful and just to be the same. But if you know things to be contrary, teach!" Of course, after this lengthy warning-reminder of the situation of individuals, including not least itinerant foreign individuals, in the cities, Hippias, vehemently swearing by Zeus, declared that he did not think that he knew anything contrary to what Socrates had been saying about the just (4.4.18; consider the public speech that Plato has Hippias report that he gives in various cities— _Hippias Major_ 286a). Hippias is no fool. So when Socrates moved to a new level, and asked, as regards the unwritten laws—which Hippias asserted to be conventionally observed in the same way in every land—if Hippias could declare that it is humans who have established these laws, Hippias of course replied no. He embraced the opinion that it is the gods who have established the unwritten laws for humans—adding, as his reason for this statement, the fact that the first of these laws among all humans is that there must be reverence for the gods. Hippias had no intention of being indicted for impiety in Athens or in any of the cities he visits. Accordingly, he made no reference, in this semipublic forum, to the causal power of nature as a source of such universal, unwritten norms, nor to any sort of normative natural right (contrast Plato, _Protagoras_ 337cff.). That such was in the back of his mind, however, became visible when Socrates proceeded to ask if it is not also conventionally held everywhere that parents must be honored, but that there is to be no sexual intercourse between parents and children. For Hippias could not bring himself to agree that the latter is a "law of god," because (he explained when questioned) he perceives people who transgress this law, with impunity. Was not Hippias conceiving of the truly universal human norms as being of such a character that, given human nature, human community is difficult to sustain without grave injury to itself and its members if these very minimal norms are not conventionally enforced? Conflict between positive human laws and these very basic, natural-conventional ( _nomikon phusikon_ ), norms or laws would be rare (Gray 2007, 9). Socrates seemed to be thinking along similar lines, though of course he too expressed his view in prudently religious terminology. For he replied that "those who transgress the laws laid down by the gods pay a penalty, which is in no way possible for a human to elude" (4.4.21). When Hippias skeptically demanded to know what was the character of this _inescapable_ "divine" penalty in the case of incest, Socrates adduced the purported biological fact of the likelihood that the sperm of men past or prior to their prime will produce defective offspring. "Who else (he said) would procreate badly, if these do not?!" This Socrates dared to declare " _the_ greatest penalty—by Zeus!" (4.4.22–23; there is at this point in the conversation an unprecedented and never-to-be-equaled flurry of Zeus-expletives by Socrates; here we have a peak of intensity of Xenophontic comedy). Xenophon and his Socrates might seem to have forgotten the very relevant fact that at the time Socrates died, the sixty-nine-year-old and his much younger wife had "very young" children (Plato, _Apology_ 34d and _Phaedo_ 116b). I am inclined to judge that this passage is a most perfect exemplification of the difference between Xenophontic and Aristophanean comedy. I note again that Shaftesbury (1964, 1: 167) refers to Xenophon as the "philosophical Menander." The serious point of Xenophon's comic production would be that he shows Socrates here, together with Hippias, presenting somewhat tongue in cheek a veiled version of a quite minimal, and not strict, conception of natural right (anticipating, we may note, the great Averroistic-Aristotelian conception that has played such an important role throughout the history of political philosophy since Aristotle). As W. K. C. Guthrie remarks, "It is noticeable that these arguments would apply equally to a world ruled not by gods but by an impersonal nature." Along these lines, Socrates went on to state the penalty for violating the universal convention dictating that one return good to those from whom one has received some benefit: the penalty is that in consequence, one becomes bereft of good friends, and has to seek out those who hate one. Swearing by Zeus, Hippias expressed his hearty agreement to "all" that Socrates had said, employing a curious formulation: "Socrates (he said), all these things befit/are _like_ gods, for it seems to me that the laws themselves have punishments for transgressors, better than a lawgiver in

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285, 6112, 8852, 13, 342, 253, 4585, 6299, 42419, 20, 283, 22, 5770, 16, 78, 63, 20, 13146, 12952, 6571, 432, 253, 2434, 16859, 15861, 267, 4752, 7121, 281, 253, 714, 1028, 37628, 22826, 13, 534, 37035, 253, 2170, 273, 690, 273, 253, 954, 33661, 11112, 63, 1012, 63, 36, 9043, 3825, 275, 776, 1263, 2170, 15, 380, 2169, 10410, 30604, 3672, 403, 2779, 2905, 281, 36680, 23281, 14800, 15, 380, 2553, 26556, 11112, 63, 1012, 63, 36, 21022, 310, 2779, 253, 906, 273, 33661, 36680, 6315, 3280, 432, 8281, 2685, 390, 1144, 37502, 460, 3275, 2879, 281, 17787, 3275, 13, 2581, 685, 1955, 281, 247, 11112, 63, 1012, 63, 36, 5802, 2380, 281, 8655, 4142, 273, 3625, 3275, 275, 253, 1527, 3617, 46, 15, 34129, 3086, 3625, 3275, 651, 2779, 906, 275, 253, 19133, 273, 11112, 63, 1012, 63, 36, 273, 3625, 18014, 984, 387, 2169, 7963, 23744, 4142, 1679, 14539, 6361, 6919, 318, 6634, 342, 1675, 281, 18224, 30770, 6315, 1309, 6315, 21746, 15, 496, 1635, 13, 8655, 23281, 4719, 476, 906, 275, 4067, 32587, 4488, 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, and accounted for anisotropy. The best model for each variable was chosen based on their root-mean-squared-standardized values (closest value to 1). Natural breaks (Jenks) were used to classify the interpolated values into categories. These models were computed using the Geostatistical Analyst Wizard. Results and discussion {#sec003} ====================== Isotopic baseline of the sGoM surface sediment {#sec004} ---------------------------------------------- The first objective of this study was to determine baselines and trends in the isotopic composition of sedimentary organic matter across the sGoM. Surface sediment of all samples range in δ^13^C values from -22.4‰ to -19.9‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}) and have an average value of -21.2 ± 0.6‰ (standard deviation; n = 73), while Δ^14^C values range from -337.1‰ to -69.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and have an average of -164.6 ± 54.0‰ (n = 72). Surface sediment of all samples range in δ^15^N values from 2.8‰ to 7.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and have an average of 4.7 ± 0.9‰ (n = 66). The %C on a carbonate-free basis range in value from 0.65% to 3.89% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and average 1.45 ± 0.59% (n = 66), while %N range in value from 0.09% to 0.49% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 0.18 ± 0.07% (n = 66). In a data set consisting of only surface sediments from the multicores (0--1 cm section), δ^13^C values range from -22.2‰ to -19.9‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of -21.0 ± 0.6‰ (n = 41), while Δ^14^C range in value from -337.1‰ to -69.2‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of -164.3 ± 63.1‰ (n = 41). δ^15^N range in value from 3.7‰ to 5.3‰ ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), and average 4.6 ± 0.4‰ (n = 37). %C range in value from 0.95% to 3.89% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 1.57 ± 0.58% (n = 37), while %N range in value from 0.14% to 0.49% ([S1 Table](#pone.0231678.s001){ref-type="supplementary-material"}), with an average of 0.20 ± 0.07% (n = 37). Due to the lack of differences, determined by T-test, in the average %C, Δ^14^C and δ^15^N values and only slight significant differences for δ^13^C and %N values (0.33‰ and 0.04%, respectively) when examining all surface sediment samples vs. only multicore (0--1 cm section) samples, we treated all samples as being representative of surficial sediment. The isoscape map of δ^13^C surface sediment organic carbon values indicates the dominance of marine production with some terrestrial inputs in the nearshore. The map reveals more δ^13^C depleted areas in the south (Bay of Campeche) and towards the Laguna de Terminos ([Fig 1](#pone.0231678.g001){ref-type="fig"} area G). This area is described as a transitional area with terrigenous clastic sediments found west of the Yucatan shelf, along the continental shelf, and biogenic carbonate deposits located on the Yucatan shelf \[[@pone.0231678.ref046], [@pone.0231678.ref047]\]. Depleted δ^13^C areas are observed along the coast, west-south-west of the Ixtoc 1 site (reference location) where three major rivers terminate into the sGoM (Grijalva-Usumacinta, Coatzacoalcos, Papaloapan; [Fig 1](#pone.0231678.g001){ref-type="fig"} areas F, E & D). Depleted δ^13^C areas are also observed along the coast from north of Tampico ([Fig 1](#pone.0231678.g001){ref-type="fig"} area C) to the Texas coastline by Corpus Christi ([Fig 1](#pone.0231678.g001){ref-type="fig"} area A). More enriched δ^13^C areas are observed offshore, in deeper water. Soto and Escobar-Briones \[[@pone.0231678.ref048]\] determined that the food web of the inner shelf mostly receives estuarine input while the food web of the middle and outer shelf receives marine carbon sources. The δ^13^C isoscape map is similar to a map of chlorophyll concentration from a 2015 satellite imagery ([Fig 2](#pone.0231678.g002){ref-type="fig"}; \[[@pone.0231678.ref049]\]). This particular chlorophyll map is generally representative of chlorophyll at other times in the GoM. Higher concentrations of chlorophyll (0.8 to 5.0 mg/m^3^) are generally observed along the Mexican and Texas coast, with the highest concentrations (\~3--5 mg/m^3^) occurring mostly from the Coatzacoalcos River to the Yucatan shelf, which encompasses the area of some of the most depleted δ^13^C sediments in our study area. The higher chlorophyll areas are likely related to terrestrial nutrient inputs. The surface sediment δ^13^C depletion is likely the result of depleted terrestrial carbon input from river flow or estuarine production added to marine production, rather than due to a δ^13^C induced response to enhanced rates of primary production in the open GoM. Enhanced primary production would likely result in the enrichment of δ^13^C of primary producers because at higher photosynthetic rates less isotopic fractionation occurs with respect to dissolved inorganic carbon during carbon fixation. In addition, enhanced nutrient concentration can result in larger phytoplankton cells which are also associated with increasing δ^13^C enrichment \[[@pone.0231678.ref050]--[@pone.0231678.ref053]\]. ![Map of chlorophyll (mg/m^3^) in the Gulf of Mexico from August 9 to 15, 2015.\ Reprinted from the USF optical oceanography lab under a CC BY license, with permission from Chuanmin Hu, original copyright 2015.](pone.0231678.g002){#pone.0231678.g002} A related spatial trend is observed on the Δ^14^C isoscape map ([Fig 3](#pone.0231678.g003){ref-type="fig"}). The area surrounding the Ixtoc 1 blowout site and towards the Laguna de Terminos consists of more modern, Δ^14^C enriched carbon, likely influenced by the Laguna de Terminos estuarine production ([Fig 3](#pone.0231678.g003){ref-type="fig"} area G) and the Grijalva-Usumacinta Rivers ([Fig 3](#pone.0231678.g003){ref-type="fig"} area F), while offshore areas are more depleted in Δ^14^C. The two most depleted sites (\# 68; IXNW1600 and \# 73; 2392) are located in water depths greater than 3000 m. These areas likely experience slower sedimentation rates and slower input rates of photosynthetically fixed marine material delivered from the surface. Areas of Δ^14^C depletion are also observed along the coastline between the Papaloapan River and Panuco River ([Fig 3](#pone.0231678.g003){ref-type="fig"} area D and C) where relatively low surface water chlorophyll appears in the satellite image ([Fig 2](#pone.0231678.g002){ref-type="fig"}). ![Map displaying the spatial trend of Δ^14^C values analyzed from 72 surface sediment samples.\ Landmark legend can be viewed on [Fig 1](#pone.0231678.g001){ref-type="fig"}.](pone.0231678.g003){#pone.0231678.g003} The isoscape map of δ^15^N in surface sediments reveals a latitudinal trend with more depleted δ^15^N areas observed around the Ixtoc 1 blowout site and the outputs of the three major rivers (Grijalva-Usumacinta, Coatzacoalcos, Papaloapan) and more enriched δ^15^N areas in the deeper waters, north of the Ixtoc 1

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or new consumer protection laws. AI also will be used by sellers of consumer products to develop lending strategies and other potential financial products that are created to boost sales and to capture market share. These new types of financial services will not only face regulatory scrutiny, but will also surely be exploited to form the basis for class actions or other business torts and similar legal action. As noted above, data development and storage will continue to surge, triggering divergent and conflicting uses. These issues raise many traditional privacy concerns and will spawn new rounds of litigation. States will enact separate statutory schemes, which will trigger unique liability issues and place increased pressure on in-house counsel to manage related litigation risks and business strategies, as further discussed below. Apart from consumers, companies will collaborate on AI implementation across international platforms, leading to a whole host of licensing agreements and business contracts that will require a new set of skills to pursue effectively AI-based claims against a competitor that fall outside the traditional patent or trade secret dispute. Disputes that arise between companies in different countries will lead to increased use of arbitration and create opportunities for creative dispute resolution strategies and a greater need for in-house counsel to manage the related business risks. To protect against civil liability, regulatory scrutiny, and reputational harm from unintended outcomes across a wide-variety of AI usage, companies need to support their AI strategies with governance structures designed and overseen by humans. The components of an effective governance strategy will differ by industry and application, but key pillars can include: Robust quality control protocols to test that those algorithmic decisions are producing outcomes that can be fairly expected by companies and their customers. The deployment of AI throughout numerous industries will put strain traditional infrastructure and systems that exist to manage litigation risks across key business platforms and create an urgent need for new protocols. These protocols should be risk based; more consequential applications (e.g., decisions impacting healthcare or personal finance) should be more tightly overseen than those with less impact on consumers (e.g., recommendations for products or entertainment content that a consumer might like based on prior purchases). Policies and procedures to reduce the risk that algorithmic training data at the front end and outcomes at the back end are infected by unintended biases, particularly in the consumer, financial, housing, and employment contexts. Commitments to transparency and accountability. Companies should consider when and how to give notice (to consumers and business partners) that decisions impacting them will be made on an automated basis. Companies should also consider creating procedures for redress when a consumer believes he or she has been treated unfairly by an algorithmic decision-making process. Internal qualifications requirements for AI operators. This will demonstrate responsible oversight by ensuring that only qualified individuals with the right technical competencies are employed in AI-related positions. Statements of values and ethics. Just as companies often express the general principles that drive their businesses, an increasing number are now articulating those principles that animate and surround their development and deployment of AI. This can include statements emphasizing commitments to quality outcomes, consumer privacy, safety, unbiased and fair decisions, and transparency around the use of AI. VIII. Conclusion and a Look Ahead The economic and societal benefits of AI will be profound, but so too are the risks and people’s concerns about how automated processes will impact them and their families. As companies deploy AI-driven services and products, they need to expect that these risks and concerns will manifest in various forms of litigation, regulatory enforcement, and protest, placing a premium on the ability to understand and explain artificial intelligence and the decisions that the owners of a business make to implement this technology. Creating and constantly refining sound governance principles at the ground level will help companies answer these concerns and comply with existing legal regimes—and ultimately mitigate their potential for undermining business objectives and triggering legal liability. Conducting this front-end compliance and governance work under the attorney-client privilege is an essential process to ensure that businesses can ask the hard questions, make the difficult risk-based decisions, and proceed with confidence. Please contact any of the authors, or your usual contact at Paul Hastings, to ask further about the ways we are helping our clients navigate their AI-related development, growth, and compliance strategies.Q: How to add two or more buttons to annotationView: MKAnnotationView? I want to have a MKAnnotationView to my pins on map (using MapKit) with next attributes: 1) image 2) details button 3) another details button 4) another details button? I have done actually adding image and details button with next code: annotationView.detailCalloutAccessoryView = snapshotView // snapshot view is a custom view // with image and its constraints let detailsButton = UIButton(type: .detailDisclosure) annotationView.rightCalloutAccessoryView = detailsButton So, the question is how to add more than one button to MKAnnotationView? Because all the tutorials that I've ever seen only is "how to add details button". A: I have done it From documentation left and right calloutAccessoryView are low width and height. So, we can add buttons and image only in detailCalloutAccessoryView. Here is my code. It's working. I haven't done a review. Because it's more clear for understanding. func mapView(_ mapView: MKMapView, didSelect view: MKAnnotationView) { if !(view.annotation! is MKUserLocation) { let customPin = view.annotation as! CustomPin self.spotDetailsForSendToPostsStripController = customPin.spotDetailsItem // its for sending to another controller. configureDetailView(annotationView: view, spotPin: customPin.spotDetailsItem) } } func mapView(_ mapView: MKMapView, viewFor annotation: MKAnnotation) -> MKAnnotationView? { if annotation is MKUserLocation { return nil } if !(annotation is CustomPin) { return nil } let identifier = "CustomPin" var annotationView = mapView.dequeueReusableAnnotationView(withIdentifier: identifier) if annotationView == nil { annotationView = MKPinAnnotationView(annotation: annotation, reuseIdentifier: identifier) annotationView?.canShowCallout = true } else { annotationView!.annotation = annotation } return annotationView } func configureDetailView(annotationView: MKAnnotationView, spotPin: SpotDetailsItem) { let width = 250 let height = 250 let snapshotView = UIView() let views = ["snapshotView": snapshotView] snapshotView.addConstraints(NSLayoutConstraint.constraints(withVisualFormat: "H:[snapshotView(250)]", options: [], metrics: nil, views: views)) snapshotView.addConstraints(NSLayoutConstraint.constraints(withVisualFormat: "V:[snapshotView(250)]", options: [], metrics: nil, views: views)) let imageView = UIImageView(frame: CGRect(x: 0, y: 0, width: width, height: height - 40)) // configure button1 let button1 = UIButton(frame: CGRect(x: 0, y: height - 35, width: width / 2 - 5, height: 35)) button1.setTitle("Info", for: .normal) button1.backgroundColor = UIColor.darkGray button1.layer.cornerRadius = 5 button1.layer.borderWidth = 1 button1.layer.borderColor = UIColor.black.cgColor button1.addTarget(self, action: #selector(MainFormController.goToInfo), for: .touchDown) // configure button2 let button2 = UIButton(frame: CGRect(x: width / 2 + 5, y: height - 35, width: width / 2, height: 35)) button2.setTitle("Posts", for: .normal) button2.backgroundColor = UIColor.darkGray button2.layer.cornerRadius = 5 button2.layer.borderWidth = 1 button2.layer.borderColor = UIColor.black.cgColor button2.addTarget(self, action: #selector(MainFormController.goToPosts), for: .touchDown) // configure image let image = UIImage(contentsOfFile: "plus-512.gif") imageView.image = image // implement your own logic imageView.layer.cornerRadius = imageView.frame.size.height / 10 imageView.layer.masksToBounds = true imageView.layer.borderWidth = 0 imageView.contentMode = UIViewContentMode.scaleAspectFill // adding it to view snapshotView.addSubview(imageView) snapshotView.addSubview(button1) snapshotView.addSubview(button2) annotationView.detailCalloutAccessoryView = snapshotView } func goToPosts() { print("go to posts") // your implementation(segues and etc) } func goToInfo() { print("go to info") // your implementation(segues and etc) } CustomPin

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, que dès qu'il s'agissait de litiges commerciaux, cette grande firme qu'était Athènes se comportait avec une loyauté parfaite. Soit qu'elle contractât avec les cités fédérées ou d'autres villes des conventions de droit privé international (δίϰαι άπὸ συμбόλων), soit qu'elle s'en tînt à des relations réglées par la coutume, elle cherchait à faire prévaloir ce principe de droit consulaire, que le demandeur devait plaider dans la ville du défendeur . Mais, comme les Athéniens en étaient les mauvais marchands , ils se virent obligés de restreindre l'application de ce principe, en exigeant que pour tout contrat conclu à Athènes le tribunal athénien fût seul compétent . Poussant jusqu'au bout la politique d'unification, Athènes prétendit imposer à l'empire son système de poids, mesures et monnaies. D'elles-mêmes, les petites villes avaient cessé, des leur entrée dans la confédération, de frapper d'autres pièces que le billon nécessaire au marché local. Plusieurs grandes villes coupables de défection se virent enlever une prérogative attachée à la souveraineté. En fait, les « chouettes » du Laurion étaient à peu près les seules monnaies d'argent que les matelots de la flotte rapportaient dans les villes et que les villes renvoyaient sous forme de tribut ; le talent et le pied attiques étaient familiers aux marchands de tous les ports. Un décret, proposé par un nommé Cléarchos, prescrivit à toutes les cités de l'empire l'usage exclusif des étalons athéniens et leur fit défense de frapper de la monnaie d'argent. Il faut croire que le décret rencontra des résistances sérieuses, car il en fallut un second (avant 420) pour ordonner aux particuliers d'échanger l'argent étranger contre de l'argent attique . Par ce complet mépris de tout ce qui rappelait l'autonomie, l'empire d'Athènes parut à ses sujets une tyrannie. Les Athéniens étaient les premiers à le dire ; ils justifiaient leur politique en invoquant avec Périclès les services qu'ils avaient rendus et continuaient de rendre, ou bien en déclarant avec la brutalité d'un Cléon que, sur la voie où l'on était engagé, il n'y avait plus à revenir en arrière, mais à briser tous les obstacles. Et ainsi, les cités qui s'étaient unies pour assurer leur liberté se sentaient asservies, et un Athénien pouvait s'indigner qu'on les traitât comme esclaves à la meule . Elles payaient tribut pour embellir Athènes et enrichir sa déesse. Elles étaient obligées d'envoyer des délégués aux Dionysies pour y apporter la somme exigée, aux Panathénées pour offrir des victimes au prix fort, aux fêtes d'Éleusis pour consacrer aux déesses les prémices de la récolte annuelle . Elles étaient maintenues dans le droit chemin de la démocratie, contraintes à l'obéissance et à la fidélité par les archers et les hoplites qui campaient sur leur acropole, par les trières qui stationnaient dans leur port, par les clèrouques établis par milliers sur leur sol. Le mécontentement couvait dans toutes les parties de l'empire. Longtemps il fut impuissant : à des cités isolées, séparées par de grandes distances, tout effort collectif était impossible contre les maîtres de la mer. Enfin les Spartiates donnèrent le signal de la grande lutte contre Athènes ; dès le premier jour ils proclamèrent la guerre de délivrance. De fait, l'empire devait succomber moins encore sous les attaques furieuses dirigées du dehors que par le travail de sape exécuté sans relâche par les ennemis de l'intérieur. L'autonomie se vengeait d'une centralisation odieuse pour des Grecs. Elle était tellement intraitable, cette autonomie des petites cités, qu'elle n'admettait même pas aussi facilement qu'on pourrait le croire la solidarité internationale des partis. Cléon ne comprend pas qu'on distingue, parmi les Mytiléniens rebelles, les démocrates des oligarques : pour lui, ils sont tous également coupables . Et, quand on demande au peuple athénien, par mesure de salut public, de permettre aux villes alliées un changement de constitution dans le sens oligarchique, Phrynichos s'y oppose. À quoi bon ? « Ce ne serait ni un motif de soumission pour les cités révoltées, ni un gage de fidélité pour celles qui nous restent ; car, plutôt que d'être esclaves de l'oligarchie ou de la démocratie, elles préfèrent être libres sous n'importe lequel de ces gouvernements . » Pourtant l'impérialisme des Athéniens n'était que prématuré et ne fut pas inutile. La grande faute d'Athènes – faute inévitable à cette époque – est de n'avoir pas compris que, si elle faisait brèche dans le droit des autres cités, elle devait leur ouvrir largement le sien. Sous le coup de la défaite, des esprits audacieux y songèrent ; mais il était déjà trop tard, et l'on attendit encore les désastres suprêmes pour faire une application exceptionnelle et désespérée d'une idée que Rome un jour rendra si féconde . Telle quelle, la tentative de Périclès et de ses successeurs a eu de grands résultats, non pas seulement pour Athènes, qui n'aurait pas laissé un si grand nom, si elle n'avait pas été la capitale d'un si grand empire, mais pour l'empire lui-même et pour toute la Grèce. Ce sont les vices du système qui attirent toujours l'attention, parce que les anciens n'ont jamais vu et qu'à leur suite les modernes ne regardent guère que le côté politique des événements. Mais à d'autres points de vue, et même à celui-là, l'empire athénien a rendu les plus grands services en créant de précieux éléments d'unité. Par l'intermédiaire des cités confédérées, la démocratie a, malgré tout, fourni à l'ensemble des Grecs un modèle qui n'a plus cessé de s'imposer. Grâce au libéralisme commercial auquel les Athéniens ne renonçaient en pleine guerre que pour assurer leur subsistance et se procurer des matériaux de construction navale, le bassin de la Méditerranée constituait un marché unique dont l'exploitation n'enrichissait pas seulement le Pirée . Et puis, tous ces alliés qui venaient chaque année aux représentations des Grandes Dionysies et aux processions des Panathénées rapportaient chez eux et répandaient partout le goût d'une littérature et d'un art supérieurs. Enfin, de même que la France vaincue en 1815 a laissé à ses vainqueurs le code Napoléon, Athènes, avant d'être écrasée, avait répandu chez les confédérés qu'elle traînait devant ses tribunaux les principes de sa législation, si bien que beaucoup d'entre eux adoptèrent pour toujours, non pas seulement la technique de son droit, mais ses principes de liberté et de responsabilité personnelles . Ainsi, par la domination qu'elle exerça pendant trois quarts de siècle, Athènes fit beaucoup pour l'unification politique et économique, intellectuelle et juridique de la race grecque.

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Transportation Commission of Southern Nevada. “Some of these visions may eventually come to fruition. But we are not talking about them happening in the next five years even, some of them in the next 10 years.”Dedicated to delivering the best IT support for Charities Our Approach to Managed IT Support for Charities At Premier Charity Solutions, we believe that our managed support helpdesk and consultancy services are the most important part of our partnership with your charity. Our customers (including Age UK, Mencap and The FSI) share that opinion. Whether large or small, your charity relies on your IT infrastructure to carry out the work you do. Faced with tight budgets that make wasted time more costly than ever, it is essential to choose a provider with a proven track record in the third sector and a good understanding of the needs and struggles of your organisation. That's why we pride ourselves on having an industry leading IT support and consultancy services tailored to the charity sector. Our recruitment process focuses on hiring personable staff with a passion for IT – making our helpdesk more approachable and encouraging your users to develop relationships and trust with our service desk. Rather than having auto-attendants, receptionists or voicemail systems, the telephone number provided to our clients goes directly to our support team. Your Dedicated Account Manager has previously worked on our helpdesk and projects teams, giving them a unique insight into the support, planning and implementation of your charity's IT systems. Their focus is to reduce your reliance on the helpdesk services by assessing and developing the systems your staff use, leading to improved reliability and efficiency. We work hard to build an IT partnership with our charities, rather than just a support arrangement. comprehensive site survey & IT audit We carry out a full site survey of your IT hardware, software and services, including a consultation with yourselves and your staff. We detail your charity’s existing IT infrastructure and discuss any additional requirements and ongoing / outstanding problems. Best practice analysis Once we have collated all of the information from the site survey of your charity, your dedicated account manager will contact you to arrange your Best Practice Analysis. This is a detailed document providing information on any areas of concern with your existing system as well as information on security, compliance and business continuity. We also specify any upcoming renewals or out-of-date solutions and provide information on forthcoming technologies and services that may benefit your charity. Pro-active real time monitoring Pro-active real-time monitoring and reporting enables us to detect and resolve many support issues before they impact your charity. We monitor every server, device and cloud service using a multitude of alerting, monitoring and reporting tools. facilities & update management All new, change and remove user requests are managed to ensure organisational compliance and identified to provide change tracking and reporting. This also includes software update control, data backup, restoration, server maintenance (automated as well as manual) and administration. third party software & hardware vendor support Where authorised, we will liaise with all your third-party hardware, software, telecommunications and cloud service providers on your behalf. This gives you one point of contact for all IT related issues and requests, saving your staff time, as well as the frustration of being pushed between service providers – and allowing us to have a full audit trail for all services and supplier requests. Dedicated account management Your dedicated account manager will contact you periodically to arrange a meeting or a call to discuss various aspects of your agreement, including feedback on our support team, a review of your ticket and service history, any noted areas of concern, completed / upcoming projects and any future requirements or new technologies. Having trouble with your IT? Transition process Site Survey & IT Infrastructure Audit A full site survey of your IT hardware, software and services including consultation with yourselves and your staff. We detail your existing IT infrastructure and discuss any additional requirements and ongoing / outstanding problems; please collate as much information as possible prior to the survey. Support: Online! That’s it! No problem too big or too small, start calling our team today! Following the site survey, we will have everything we need to start providing you with a fully managed helpdesk! Remaining Information Requested from Suppliers Just like switching your gas or electricity we do all of the hard work, contacting previous IT suppliers and 3rd party vendors, requesting information, detailing equipment, obtaining password etc. and all you have to do is to continue doing what you do best; running your organisation! Concerned your previous supplier’s wont hand everything over in a timely manner? Don’t be, we will liaise with your previous supplier directly and in the event they don’t provide the information requested, your dedicated project lead will reset any outstanding passwords and re-configure any equipment, software or services! Best Practice Analysis Once we have collated all of your information following your site survey, your dedicated account manager will contact you to arrange your Best Practice Analysis. This is a detailed document providing information on any areas of concern with your existing system, notification of any upcoming renewals or out-of-date solutions, as well as information on forthcoming technologies and services that may benefit your organisation. Regular Account Review Meetings & Consultancy Our account manager will contact you periodically to arrange a meeting or a call to discuss various aspects of your agreement, including feedback on our support team, a review of your ticket and service history, any noted areas of concern, completed / upcoming projects and any future requirements or new technologies Service Desk Statistics Average Telephone Response Time: 8 Seconds % SLA Target Hit: 99.6% % Incidents Resolved on Initial Contact: 76% % Incidents Resolved Without Escalation: 84% % Incident Tickets Re-Opened: 2.1% % Incidents Escalated to On-Site Engineer Visit: 0.3% Our Partners Get your quote now Name* Email Address* Telephone* Company Name Number of Users* Details* Marketing Permissions Premier Charity Solutions will use the information you provide on this form to be in touch with you and to provide updates and marketing. Please let us know all the ways you would like to hear from us: EmailDirect MailCustomised online advertising You can change your mind at any time by clicking the unsubscribe link in the footer of any email you receive from us, or by contacting us at [email protected]. We will treat your information with respect. For more information about our privacy practices please visit our website. By clicking below, you agree that we may process your information in accordance with these terms. We use MailChimp as our marketing automation platform. By clicking below to submit this form, you acknowledge that the information you provide will be transferred to MailChimp for processing in accordance with their Privacy Policy and Terms.Development of nonstoichiometric CuInS₂ as a light-harvesting photoanode and catalytic photocathode in a sensitized solar cell. A simple one-pot approach was developed to obtain nonstoichiometric CuInS2 nanocrystals. Using this approach, both In-rich and Cu-rich CuInS2 nanocrystals could be reliably synthesized by tuning stoichiometric combinations of [Cu]/[In] precursor constituents. By designing Cu-rich CuInS2 heteronanostructures to serve as counter electrodes, quantum-dot-sensitized solar cells (QDSSCs) equipped with In-rich CuInS2 and CdS cosensitizers delivered a power conversion efficiency of 2.37%, which is significantly more efficient than conventional Pt counter electrodes. To the best of our knowledge, this study represents the first report utilizing nonstoichiometric CuInS2 nanocrystals as a photon-harvesting sensitizer comprised of a photoanode and photocathode in QDSSCs; also unique to this report, these nonstoichiometric CuInS2 nanocrystals were formed by simply changing the cationic molar ratios without complicated precursor preparation. Impedance spectroscopy and Tafel polarization indicated that these Cu-rich CuInS2 heteronanostructures had electrocatalytic activities (used for reducing S(2-)/Sn(2-)) that were superior to a Pt catalyst. Moreover, we demonstrated that Cu-rich CuInS2 heteronanostructures were also useful counter electrodes in dye-sensitized solar cells, and this finding revealed a promising conversion efficiency of 6.11%, which was ∼96% of the efficiency in a cell with a Pt-based counter electrode (6.32%).MRI of oriental cholangiohepatitis. Oriental cholangiohepatitis (OCH) also called recurrent pyogenic cholangitis is characterized by intrahepatic duct calculi, strictures, and recurrent infections. In turn cholangitis can result in multiple hepatic abscesses, further biliary strictures, and in severe cases, progressive hepatic parenchymal destruction, cirrhosis, and portal hypertension. Magnetic resonance cholangiopancreatography (MRCP) and conventional T1-weighted (T1W) and T2-weighted (T2W) magnetic resonance imaging (MRI) findings have been described in patients with OCH. MRCP findings include duct dilation, strictures, and calculi. MRCP can help to localize the diseased ducts and determine the severity of involvement. T1 and T2W sequences reveal the parenchymal changes of atrophy, abscess formation, and portal hypertension in addition to calculi. Post-treatment changes

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not best developers) win contracts. ~~~ shawkinaw So we have a choice between corruption and incompetence ... I'm pretty sure that corruption would actually be better, at least shit would work. ~~~ thebulge We only have a choice of which we want to start with. Eventually we end up with both. ------ coherentpony No shit. This whole ordeal has been nothing short of a complete and utter fucking disaster. And how much did the government pay to have this work done [1]? This is procurement at its finest. The government could have easily paid 10% of what they did to a tech start-up who would have done a much better job utilising scalable technologies. [1] [http://www.washingtonpost.com/blogs/fact- checker/wp/2013/10/...](http://www.washingtonpost.com/blogs/fact- checker/wp/2013/10/24/how-much-did-healthcare-gov-cost/) ~~~ Iftheshoefits I rather think that depends on what technological expertise the the start-up brought to bear on the problem. I understand it's chic to think that Healtcare.gov is "just another website", especially among a certain crowd who think that all development is web development, and best done on a MacbookPro using RoR/node/<functional language Y>/Go + <insert fad-of-the-day JS framework here>. It's a mistaken impression, though, because we aren't talking about some from-scratch system. We're talking about communication with and between a lot of legacy systems requiring what is almost certainly a frankenstein-like nightmare of patchwork APIs that dive into programming languages and styles hipster 20-somethings at hot S.F. Start Up X wouldn't understand because it's beneath them (I'm exaggerating and generalizing here for effect--this isn't to impugn all 20-somethings, start- ups, etc.). Honestly I don't think there is any contractor who could have pulled this project off flawlessly, or even very much better than the group of misfits who did Healthcare.gov did, just because of the sheer complexity of the project compounded with the increased politically-motivated interference from government officials that comes with such high-profile projects. ~~~ MichaelApproved > Honestly I don't think there is any contractor who could have pulled this > project off flawlessly A few flaws could be excused but the site was a disaster. > or even very much better than the group of misfits who did Healthcare.gov In just a couple of months, the current contractor group was able to clean up most of the mess and improve the site dramatically. In just _two months_! Imagine what they could have pulled off if the group was put together earlier. ~~~ Iftheshoefits The were able to clean up and improve an existing system, yes. That doesn't imply anything about their abilities to have created it from the ground up. ~~~ MichaelApproved To me, it implies they have even more ability than if I saw them build it from the ground up. They were able to read the garbage written by the other developers and make something useful out of it. Pretty impressive! ------ hga Too many lies in this article to take more from this than the bare fact that CGI Federal will be replaced by Accenture (the latter of which is no prize from what I've heard). I.e. the government's Centers for Medicare and Medicaid Services (CMS) were notoriously the "prime contractor" until the 3rd week of October (when replaced by contractor QSSI, also responsible for the "data hub"), and the attacks on the contractors are misplaced when their management was so impossibly bad. The linked _Washington Post_ article is not great, but better: [http://www.washingtonpost.com/politics/obama- administration-...](http://www.washingtonpost.com/politics/obama- administration-to-end-contract-with-cgi-federal-company-behind- healthcaregov/2014/01/10/001eb05a-719e-11e3-8b3f-b1666705ca3b_story.html) ~~~ coldcode Accenture taking over is like replacing dumb & dumber with larry, moe and curly. ------ greg5green >>Accenture, which is one of the world’s largest consulting firms, has extensive experience with computer systems on the state level, and it built California’s new health insurance exchange. Hasn't California's exchange had big problems too? ~~~ angersock Accenture is Arthur Andersen, and they've got a long history of extracting maximum value for shareholders from government contracts (state and local). EDIT: Arthur Andersen spawned Andersen Consulting spawned Arthur Anderson Business Consulting spawned Accenture. Some of AABC splintered off and joined Hitachi Consulting, some went elsewhere. The history of computer consulting is varied, interesting, and tragic. ------ patrickg_zill Am I the only one who thinks that the failures were intentional - that the whole mix-up is a passive-aggressive way of herding the USA into eventual single-payer? If Washington DC is, in fact, really that stupid and it is not intentional, under what strange notion of justice am I to pay taxes to these morons? ~~~ smsm42 Depends on what you mean by intentional. I'm not sure if the guys that call the shots are Machiavellian enough for such things - given how incompetent they are in everything else, hard to imagine they would be super-competent in long-reaching plots. If they had been able to execute long-running plans of such magnitude with such certainty, they wouldn't screw up so many things so badly as they had. However, the resulting vector of their efforts and failures may very well point into that direction, and not without their cooperation and help, since once they beat insurance industry into full dependency and make the population rely on subsidized care, the next logical step would be to eliminate the middlemen - there would be no point for them to exist anymore, at least not as independent entities - given that they would have no independence as such and serve no useful function in such setup. ------ bane One of the differences between creating and enforcing laws and creating software is that software _actually_ has to work. The efficacy of a law is open to endless debate, and it doesn't actually have to end up with any intended effect. But software, you can't legislate software. It's obvious that government shouldn't be in the software business, and the government would agree "that's why we use contractors for this!". But when 100% of your revenue comes from the government, in a way you're basically the same thing. ------ protomyth The government isn't exactly doing too well with any of its software projects. The IRS had problems during tax season and the FBI has cancelled and restarted multiple times. The Dept of Interior has been held in contempt of court for how bad their systems have been. ------ dreamfactory2 Talk about going from the frying pan to the fire. ------ wehadfun I here the points about about legacy systems. How much would it have cost to scrap those old systems and build from the ground up. ------ sciguy77 Is anyone surprised by this? ~~~ larockt Slightly surprised, but only because I would have thought that the company had kept up their payments to the necessary campaign funds. Q: Copy from excel and paste into online form Firstly may I apologise for the fact that I am not the best with computers, I have quite a large excel sheet for which I have to copy and paste 10 columns per row into an online form. Is it possible to create a macro for this and if yes how can I do so. Also please keep in mind that I am at work, so I'm limited from the use of plugins and I unfortunately have to use internet explorer. Your help would be much adored, Thank You A: Yes it is possible. You can use IE to automate this using vba. Sub xtremeExcel() Dim HTMLDoc As HTMLDocument Dim oBrowser As InternetExplorer sURL = "*******Paste URL Here************" Set oBrowser = New InternetExplorer oBrowser.Silent = True oBrowser.navigate sURL oBrowser.Visible = True Do Loop Until oBrowser.readyState = READYSTATE_COMPLETE Set HTMLDoc = oBrowser.document 'Use firebug to identify the textbox or object you need. and you can set its value like 'HTMLDoc.GetElementByID("abcd").value

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Fidesz-MPP won by forming a coalition with the MDF and the conservative Independent Smallholders. The party's youthful leader, Viktor Orbán, was named prime minister. The electorate grew increasingly hostile to Fidesz-MPP's strongly nationalistic rhetoric and unseated the government in April 2002, returning the MSZP, allied with the SZDSZ, to power under Prime Minister Péter Medgyessy, a free-market advocate who had served as finance minister in the Horn government. In August 2004, amid revelations that he had once served as a counterintelligence officer, Medgyessy resigned and Sports Minister Ferenc Gyurcsány of the MSZP was named premier. Hungary became a fully fledged member of NATO in 1999 and, with nine so-called accession countries, was admitted into the EU in May 2004. Alan Parker's 1996 film _Evita_ was filmed in Budapest. The Buenos Aires cathedral on screen is the Basilica of St Stephen, the grand, tree-lined boulevard is Andrássy út and the swarthy horse guards belong to the Hungarian mounted cavalry. ## At Home at Last Reappointed prime minister in April 2006 after the electorate gave his coalition 55% of the vote, Gyurcsány began a series of austerity measures to tackle Hungary's budget deficit, which had reached a staggering 10% of GDP. But in September, just as these unpopular steps were put into place, an audiotape recorded shortly after the election at a closed-door meeting of the prime minister's cabinet had Gyurcsány confessing that the party had 'lied morning, noon and night' about the state of the economy since coming to power and now had to make amends. Gyurcsány refused to resign, and public outrage led to a series of demonstrations near the Parliament building in Budapest, culminating in widespread rioting that marred the 50th anniversary of the 1956 Uprising. After that violent demonstrations became a not-infrequent feature on the streets of Budapest and other large cities, especially during national holidays. The radical right-wing nationalist party Jobbik Magyarországért Mozgalom (Movement for a Better Hungary) has been at the centre of many of these demonstrations and riots. Gyurcsány led a feeble minority government until general elections in 2010 when Fidesz-MPP won a majority of 52% in the first round of voting and joined forces with the Christian Democratic People's Party (KDNP) to rule with a two-thirds majority in parliament Hungary's most recent appearance on the world stage came in 2011 when it assumed presidency of the EU Council. A new constitution came into effect at the start of 2012. In the April 2014 national elections, the first since constitutional changes reduced voting to a single poll and the number of MPs from 386 to 199, Fidesz took almost 45% of the vote and 133 seats, returning Orbán to the premiership. Orbán was clearly in charge once again but 'Viktátor', as the opposition press nicknamed him, was frequently criticised for strong-armed tactics and abuse of power. At the time of research Orbán was still at the helm but his ship did not appear to be on course. In 2007 János Kádár's grave in Budapest's Kerepesi Cemetery was broken into and his skull and assorted bones were removed. The only clue was a note that read: 'Murderers and traitors may not rest in holy ground 1956–2006'. The remains have never been recovered. #### Timeline AD 106 Roman Aquincum in today's Óbuda becomes the administrative seat of the province of Pannonia Inferior and a fully fledged colony less than a century later. Late 430s Aquincum offers little protection to the civilian population when the Huns burn the colony to the ground, forcing the Romans and other settlers to flee. 896–98 Nomadic Magyar tribes set up camp in the Carpathian Basin, with five of the seven original tribes settling in the area that is now Budapest. 955 Hungarian raids outside the Carpathian Basin as far as Germany, Italy and Spain are stopped for good by German king Otto I at the Battle of Augsburg. 1000 Stephen (István in Hungarian) is crowned 'Christian King' of Hungary at Esztergom on Christmas Day; he is canonised as St Stephen in 1083. 1222 King Andrew II signs the Golden Bull, according the nobility increased rights and powers; it is renewed nine years later. 1241–42 Mongols sweep across Hungary, reducing the national population by up to a half and killing some 100,000 people in Pest and Óbuda alone. 1458–90 Medieval Hungary enjoys a golden age under the enlightened reign of King Matthias Corvinus and Queen Beatrix, daughter of King Ferdinand I of Naples. 1514 A peasant uprising is crushed, with 70,000 people executed, including leader György Dózsa, who dies on a red-hot iron throne fitted with a scalding crown. 1526 Hungary is soundly defeated by the Ottomans at the Battle of Mohács and young King Louis is killed; the ensuing Turkish occupation lasts more than a century and a half. 1541 Buda Castle falls to the Ottomans; Hungary is partitioned and shared by three separate groups: the Turks, the Habsburgs and the Transylvanian princes. 1686 Austrian and Hungarian forces backed by the Polish army liberate Buda from the Turks; peace is signed with the Ottomans at Karlowitz (now in Serbia) 13 years later. 1703–11 Ferenc Rákóczi II fights and loses a war of independence against the Habsburgs; he is given asylum in Thrace by the Turkish Sultan Ahmet III. 1795 Seven pro-republican Jacobites, including the group's leader Ignác Martonovics, are beheaded at Vérmező (Blood Meadow) in Buda for plotting against the Habsburg throne. 1848–49 During the War of Independence, poet Sándor Petőfi dies fighting, Lajos Batthyány and 13 of his generals are executed for their roles and Lajos Kossuth goes into exile. 1867 The Act of Compromise creates the Dual Monarchy of Austria (the empire), based in Vienna, and Hungary (the kingdom), with its seat at Budapest. 1896 The millennium of the Magyar 'conquest' of the Carpathian Basin is marked by a major exhibition in City Park that attracts four million people over six months. 1918 Austria-Hungary loses WWI in November and its political system collapses; Hungary declares itself a republic under the leadership of Count Mihály Károlyi. 1919 Béla Kun's Republic of Councils, the world's second communist government after the Soviet Union's, lasts for five months until Kun is driven into exile by the Romanian army. 1920 Treaty of Trianon carves up much of Central Europe, reducing Hungary's territory by almost two-thirds and enlarging the ethnic Hungarian populations in Romania, Yugoslavia and Czechoslovakia. 1939 Nazi Germany invades Poland; Britain and France declare war on Germany two days later but Hungary remains neutral for two years when it joins the Axis led by Germany and Italy. 1944 Germany invades and occupies Hungary; most Hungarian Jews, who had largely been able to avoid persecution under strongman Miklós Horthy, are deported to Nazi concentration camps. 1945 Budapest is liberated by the Soviet army in April, a month before full victory in Europe, with three-quarters of its buildings and all of its bridges in ruins. 1949 The communists, now in complete control, announce the formation of the 'People's Republic of Hungary'; Stalinist show trials of 'Titoists' and other 'enemies of the people' begin. 1956 Budapest is in flames after riots in October; Hungary briefly withdraws from the Warsaw Pact and proclaims its neutrality but the status quo is restored and János Kádár installed as leader. 1958 Imre Nagy and others are executed by the communist regime for their role in the uprising and buried in unmarked graves in Budapest's New Municipal Cemetery. 1963 Amnesty is extended to those involved in the 1956 Uprising by the communist government after a UN resolution condemning the suppression of the rebellion is struck from the agenda. 1968 Plans for a liberalised economy are introduced in an attempt to overcome the inefficiencies of central planning but are rejected as too extreme by conservatives. 1978 The Crown of St Stephen is returned to Hungary from the USA, where it had been held at Fort Knox in Kentucky for safekeeping since the end of WWII. 1988 János Kádár is forced to retire in May after more than three decades in power; he dies and is buried in Budapest's Kerepesi Cemetery the following year. 1989 The electrified fence separating Hungary and Austria is removed in July; communist power is relinquished; the Republic of Hungary

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to the tune of taylor swift (complete with dance moves) Chef Crawford prepared pasta for us in several ways. First we enjoyed a duo of rotini with marinara sauce and spaghetti with basil pesto. Sooo good! I finished every last bite, which shows that healthy eating doesn't have to be boring - Catelli's Ancient Grains pasta tastes great and delivers a ton of nutritional benefits. In fact, I liked the taste and texture better than regular whole wheat pasta. This Ancient Grains pasta will be my new go-to choice for delicious and healthy dinners (or lunches... or any other time I need some pasta!) After Chef Crawford's cooking demo we moved into smaller groups to try our hands at preparing 'Chilled Noodle Salad with Ginger Wasabi Dressing' using Ancient Grains Spaghettini. It had a ton of fresh, crunchy vegetables and the noodles held up really well to the zippy dressing. I'll definitely be making this one again - in fact I'm already imagining enjoying this tasty salad by the bowlful for summer evening dinners on the patio. Chilled Noodle Salad with Ginger Wasabi Dressing 1 pkg Catelli Ancient Grains Spaghettini 2 cups snowpeas, blanced in hot water, then thinly sliced on a diagonal 1 cup shelled edamame beans 1 cup red pepper, cut into matchsticks 1 small long english cucumber, seeded and thinly sliced 2 cups napa cabbage, finely shredded 3 green onions, thinly sliced 1/4 cup seasoned rice vinegar 3 tbsp canola oil 2 tbsp soy sauce 1 tsp lemon zest 2 tbsp lemon juice 2 tsp brown sugar 2 tsp sesame oil 2 tsp fresh grated ginger wasabi to taste 1 ripe avocado, sliced 1/4 cup fresh cilantro leaves 2 tbsp black sesame seeds Prepare the pasta according to the directions on the package. Rinse with cold water and drain well. Toss with a few tbsp of canola oil and set aside. While the pasta is cooking, prepare all the vegetables. Add the rice vinegar, canola oil, soy sauce, lemon zest & juice, brown sugar, sesame oil, ginger and wasabi into a jar with a lid (or something similar). Shake everything together until mixed well. (According to Chef Crawford shaking is better than mixing, especially if you're dancing at the same time). Toss the salad dressing with all of the prepared vegetables. Put into a large serving bowl and top with avocado slices, cilantro leaves and black sesame seeds. The event was held at Get Cooking. Their kitchen is beautiful! All of the staff were so friendly and helpful. Get Cooking prepared several appetizers for us and everything was super tasty. I loved the chickpea pancake with kale on top and the beet macaron with hummus filling. This was the first time I had heard of Get Cooking, but I'd love to go back and take one of their cooking classes some time. Messy Little Cook Test Hi, I'm Courtenay. I truly am the 'Messy Little Cook' - there's sure to be a mountain of dirty dishes and flour all over the place whenever I'm playing in the kitchen. I also love writing about restaurants, other foodie stuff and travel (when I get the chance). Looking for something? To Follow me on Pinterest or Instagram click on the icons below: Two little ballerinas 💕 #mayowskifamily Walking my big girl to the school bus ☀️#beautifulfallmorning #mayowskifamily Camping in Banff for the long weekend 💕 We played, paddleboarded, hiked to the tea house, ate ice cream, roasted marshmallows and had a great time together as a family. #mayowskifamilycamping #campingwithkids #banffnationalpark #getoutside #mayowskifamily In that last video of Hannah, the first time (off camera) she told me she loved s'mores more than me 🥺 she's working on being funny - and it actually is pretty funny Huge THANKS to @bagelbar.yeg and @derosebrosmeats for the bagels, cream cheese, sandwiches and tots!! I won their giveaway earlier this summer and picked it up today to share with my team at work 🤤🤤🤤 everything was thoroughly enjoyed 👍 Happy Grade 1 Hannah! #firstdayofschool #yegkids #mayowskifamily The last camping adventure of the year has begun. Tonight we're hanging out under the romantic lights of...the Bass Pro shop parking lot and listening to the soothing sounds of QE2 traffic 🙃 #parkinglotcamping #mayowskifamily Today is our 10th anniversary ♥️ So I'm sharing 10 of my memories from our wedding day. A walk down memory lane, August 21, 2009 1) So unbelievably happy to married to this guy 😍 2) Getting ready with our moms, my sister and future sister-in-law. It felt like the greatest game of dress-up ever. I loved my wedding dress and veil 3) Walking down the aisle with my parents. I wish I could go back in time to slow this moment down. I could feel their love, support and pride 4) Seeing Trevor waiting for me at the end of the aisle. My heart was filled with butterflies, but I couldn't wait to be there with him 5) Crying while saying my vows. I knew I would cry - I'm surprised I actually got through it 6) You may kiss the bride! I made Trev practice "the kiss" before the wedding 😘 7) So greatful for our family and friends who celebrated with us 8) We slipped into the Winspear auditorium for a few photos before the reception. It felt glamorous and special to stand on the stage under the lights. While Kelsy was taking our photos the man tuning the organ was also snapping our pic 9) I surprised Trevor with an extra wedding cake (chocolate mint flavor) to apologize for my bridezilla moment when I told him that was not an acceptable wedding cake flavor 😂 everyone loved the chocolate mint cake 10) Hanging out in downtown Edmonton taking pictures with my favorite people. Everyone else was good at the sexy/serious face...me, not so much, haha. I just couldn't hide my huge smile. Happy anniversary Trevor, I love you forever ♥️ 📸@kelsynielson @edmontonfamilyphotographer #tenthanniversary #weddingmemories #yegweddings #husbandandwife #10yearslater #mayowskifamily Trev made an excellent dinner of mussels in wine with homemade mayo and oven fries. The kids devoured everything. My feeding-therapist heart was glowing with pride as the kids gobbled down the mussels and asked for more (even though this kind of thing doesn't happen all the time) #adventurouseaters #dadmadedinner #foodiekids We're really good at family pictures 🤦#mayowskifamily Checking out the playground Trev used to play on when he was a kid, feeding Rose the Squirrel (as named by the kids) and one last popsicle before the long drive home #mayowskifamily More beach and s'mores please! #campingincanada #mayowskifamily Nate was so excited to take me for a ride on the board, he was shouting take my picture, it's my first paddle! Once the kiddos were asleep Trev and I got to enjoy a sunset walk along the lake #mayowskifamily Family camping trip to Kimball Lake. The mornings were cool, but the afternoons were warm enough to enjoy the beautiful beach. My nature kids loved it #mayowskifamily/*************************************************************** * * Copyright (C) 1990-2007, Condor Team, Computer Sciences Department, * University of Wisconsin-Madison, WI. * * Licensed under the Apache License, Version 2.0 (the "License"); you * may not use this file except in compliance with the License. You may * obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * ***************************************************************/ #include "condor_common.h" #include "condor_config.h" #include "condor_attributes.h" #include "condor_commands.h" #include "daemon.h" #include "dc_starter.h" int sendCmd( const char* starter_addr ); int main( int argc, char* argv[] ) { config(); switch( argc ) { case

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1896, 15, 187, 16956, 595, 18528, 26875, 476, 320, 1114, 375, 538, 23572, 390, 23567, 538, 23572, 13, 352, 1146, 1896, 323, 253, 10829, 44385, 275, 2709, 35225, 281, 320, 8931, 390, 1027, 15, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 18, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 19, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 18, 14, 20, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 38861, 7006, 273, 253, 7212, 313, 42, 14, 22, 14, 66, 10, 534, 778, 320, 5393, 275, 1635, 281, 253, 7006, 5393, 275, 253, 9008, 6667, 403, 1110, 534, 956, 27, 187, 2042, 13, 275, 8956, 342, 1232, 313, 35, 582, 30097, 473, 14, 15830, 19, 13, 23, 14, 69, 40780, 80, 14, 21, 14, 13006, 4587, 22451, 28152, 12977, 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2x80x83or represents phenoxy-C1-C4-alkyl which is optionally substituted by fluorine, chlorine, methyl or ethyl, or xe2x80x83represents pyridyloxy-C1-C4-alkyl, pyrimidyloxy-C1-C4-alkyl or thiazolyloxy-C1-C4-alkyl, each of which is optionally substituted by fluorine, chlorine, amino, methyl or ethyl. R2 very particularly preferably represents C1-C4-alkyl, C2-C14-alkenyl, C1-C4-alkoxy-C2-C6-alkyl or poly-C1-C4-alkoxy-C2-C6-alkyl, each of which is optionally substituted by fluorine or chlorine, xe2x80x83or represents C3-C6-cycloalkyl which is optionally substituted by fluorine, chlorine, methyl, ethyl, n-propyl, iso-propyl or methoxy, xe2x80x83or represents phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, cyano, nitro, methyl, ethyl, n-propyl, i-propyl, methoxy, ethoxy, trifluoromethyl or trifluoromethoxy, R3 very particularly preferably represents methyl, ethyl, propyl or isopropyl, each of which is optionally substituted by fluorine or chlorine, or represents phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, propyl, iso-propyl, tert-butyl, methoxy, ethoxy, isopropoxy, tert-butoxy, trifluoromethyl, trifluoromethoxy, cyano or nitro. R4 and R5 independently of one another very particularly preferably represent C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylamino, di-(C1-C4-alkyl)amino or CC4-alkylthio, each of which is optionally substituted by fluorine or chlorine, or represent phenyl, phenoxy or phenylthio, each of which is optionally substituted by fluorine, chlorine, bromine, nitro, cyano, methyl, methoxy, trifluoromethyl or trifluoromethoxy. R6 and R7 independently of one another very particularly preferably represent hydrogen, or represent C1-C4-alkyl, C3-C6-cycloalkyl, C1-C4-alkoxy, C3-C4-alkenyl or C1-C4-alkoxy-C2-C4-alkyl, each of which is optionally substituted by fluorine or chlorine, or represent phenyl or benzyl, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl, or together represent a C5-C6-alkylene radical which is optionally substituted by methyl or ethyl and in which one methylene group is optionally replaced by oxygen or sulphur. R13 very particularly preferably represents hydrogen, or represents C1-C4-alkyl or C1-C4-alkoxy, each of which is optionally substituted by fluorine or chlorine, or represents C3-C6-cycloalkyl, or represents phenyl, phenyl-C1-C2-alkyl or benzyloxy, each of which is optionally substituted by fluorine, chlorine, bromine, methyl, ethyl, iso-propyl, tert-butyl, methoxy, ethoxy, iso-propoxy, tert-butoxy, trifluoromethyl, trifluoromethoxy, nitro or cyano. R14 very particularly preferably represents hydrogen or C1-C4-alkyl, or R13 and R14 together very particularly preferably represent C4-C6-alkanediyl. R15 and R16 are identical or different and very particularly preferably represent methyl or ethyl, or R15 and R16 together very particularly preferably represent a C2-C3-alkanediyl radical which is optionally substituted by methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl or tert-butyl, or by phenyl which is optionally substituted by fluorine, chlorine, methoxy, trifluoromethyl, trifluoromethoxy, nitro or cyano. The abovementioned definitions of radicals or illustrations, in general or where preferred ranges have been given, can be combined with each other as desired, that is to say combinations between the respective ranges and preferred ranges are also possible. They apply to the end products and, analogously, to the precursors and intermediates. Preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being preferred (preferable) is present. Particularly preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being particularly preferred is present. Very particularly preferred according to the invention are the compounds of the formula (I) in which a combination of the meanings mentioned above as being very particularly preferred is present. Saturated or unsaturated hydrocarbon radicals, such as alkyl or alkenyl, also in connection with hetero atoms, such as, for example, in alkoxy, can be in each case straight-chain or branched as far as this is possible. Optionally substituted radicals can be monosubstituted or polysubstituted, it being possible for the substituents in multiple substitutions to be identical or different. Individual compounds of the formula (I-1-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (I-2-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (1-3-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: Individual compounds of the formula (I-5-a) which may be mentioned in addition to the compounds mentioned in the preparation examples are those which follow: If, in accordance with process (B), ethyl O-[(2,6-dichloro-4-methyl)-phenylacetyl]-hydroxyacetate is used, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (C), ethyl 2-[(2-chloro-6-fluoro-4-methyl)-phenyl]-4-(4-methoxy)-benzylmercapto-4-methyl-3-oxo-valerate is used, the course of the process according to the invention can be represented by the following equation: If, for example, in accordance with process (E), chlorocarbonyl 2-[(2,4-dichloro-6-methyl)-phenyl] ketene and acetone are used as starting compounds, the course of the methyl)-phenyl] ketene and thiobenzamide are used as starting compounds, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (Gxcex1), 3-[(2,6-dichloro-4-methyl)-phenyl]-5,5-dimethyl-pyrrolidine-2,4-dione and pivaloyl chloride are used as starting substances, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (G) (variant xcex2), 3-[(2,4-dichloro-6-methyl)-phenyl]-4-hydroxy-5-phenyl-xcex943-dihydrofuran-2-one and acetic anhydride are used as starting compounds, the course of the process according to the invention can be represented by If, in accordance with process (H), 8-[(2,4-dichloro-6-methyl)-phenyl]-1,6-diazabicyclo-(4,3,01,6)-nonane-7,9-dione and ethoxyethyl chloroformate are used as starting compounds, the course of the process according to the invention can be represented by the following equation: If, in accordance with process (I), variant xcex1, 3-[(2,6-dichloro-4-methyl)-phenyl]-4-hydroxy-6-(3-pyridyl)-pyrone and methyl chloromonothioformate are used as starting materials, the course of the reaction can be represented as follows: If, in accordance with process (K), variant xcex2, 5-[(2-chloro-6-fluoro-4-methyl)-phenyl]-6-hydroxy-2-(4-chlorophenyl)-thiazin-4-one, carbon disulphide and methyl iodide are used If, in accordance with process (J), 2-[(2,4-dichloro-6-methyl)-phenyl]-1,5-dimethylene-pyrrolidine-2,4-dione and methanesulphonyl chloride are used as starting materials, the course of the reaction can be represented by the following equation: If, in accordance with process (K), 2-[(2,6-dichloro-4-methyl)-phenyl]-4-hydroxy-5-methyl-6-(2-pyridyl)-pyrone and 2,2,2-trifluoroethyl methanethiochlorophosphonate are used as starting materials, the course of the reaction can be represented by the following equation: If, in accordance with process (L), 3-[(2,4-dichloro-6-methyl

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$ the space of all homogeneous linear polynomials on $d$ variables of degree one satisfied by the coordinates of $X$. Applying a unitary we can always assume that $\cL_X$ is spanned by $z_k,\ldots,z_d$. In [@3S] Salomon, Shalit and the author have defined the notion of a matrix span of a set of points $\cS \subset \M_d$. Recall that the matrix span of a set $\cS$ is defined via $${\operatorname{mat-span}}(\cS)(n) = {\operatorname{Span}}\left\{ \left(I_d \otimes T \right)(X) \mid X \in \cS(n),\, T \in \cL(M_n) \right\}.$$ Here $\cL(M_n)$ stands for the linear operators on $M_n(\C)$ and for each $T \in \cL(M_n)$ we have $\left( I_d \otimes T\right)(X) = \left(T(X_1), \ldots, T(X_d)\right)$. \[lem:mat-span\] If $\cS = \{X\}$ for $X \in \M_d(n)$, then ${\operatorname{mat-span}}(\cS)(n)$ is precisely the set of points $Z \in M_d(n)$, such that $\cL_X \subset \cL_Z$. First, let us assume that $\cL_X = \{0\}$, i.e, the coordinates of $X$ are linearly independent. Then applying linear transformations $T \in \cL(M_n)$ coordinate-wise, we can get any point in $\M_d(n)$ and thus we are done. Now assume that $X = \left(X_1,\ldots,X_{k-1},0,\ldots,0 \right)$, with $X_1,\ldots,X_{k-1}$ linearly independent. As in the previous case we can get by applying linear transformations coordinate-wise any point of the form $Z = \left(Z_1,\ldots,Z_{k-1},0,\ldots,0\right)$. In particular, every such point satisfies $\cL_X \subset \cL_Z$. Applying a linear transformation on the coordinates just changes bases in the spaces of linear polynomials and thus the above statement is true for any $X$. To prove the converse inclusion observe that if $Z \in {\operatorname{mat-span}}(\cS)(n)$, then there exist a linear transformation $T \in \cL(M_n)$, such that $$Z = \left( I_d \otimes T \right)(X) = \left(T(X_1),\ldots,T(X_d)\right).$$ Hence if $p = \sum_{j=1}^d \alpha_j z_j \in \cL_X$, then by linearity $p(Z) = T(p(X)) = 0$ and thus $p \in \cL_Z$. \[prop:fixed\_level\_1\] If $f$ is an nc self-map of $\fB_d$, such that $f$ fixes the subspace of points of the form $(z_1,\ldots,z_{k-1},0,\ldots,0)$ in $\fB_d(1)$, for $k > 2$, then $f$ fixes all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$. By Lemma \[lem:one-dim\_fixed\] we know that the points $(Z_1,0,\ldots,0)$, $(0,\ldots,0,Z_{k-1},0,\ldots,0)$ are fixed by $f$. Now [@3S Lemma 8.1] implies that $\Delta f(0,0)$ fixes the matrix span of these points and thus fixes all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$. Consider the $n$-th level $\fB_d(n)$. Let $Z = (Z_1,\ldots,Z_{k-1},0,\ldots,0)$ be a point such that $Z/\|Z\|$ is coisometric. As was mentioned there is a unique geodesic passing between $0$ and $Z$ and it is just the disc through the two points. Additionally, the above argument shows that $\Delta f(0,0)(Z) = Z$ and it is the derivative of $f$ at the origin on level $n$. Applying Lemma \[lem:der\_fix\_coisom\] we get that the geodesic $w \mapsto w Z$ is fixed by $f$. By Lemma \[lem:similar\_to\_coisometry\] every generic point of the form $(X_1,\ldots,X_{k-1},0,\ldots,0)$ is similar to such a $Z$ we conclude that every generic point of this form is fixed. Since $k > 2$ the generic points are dense in the set of all points of this form and thus the entire set is fixed. This proposition combined with Lemma \[lem:one-dim\_fixed\] gives us the following corollary. \[cor:fixed\_subspace\] Let $f \colon \fB_d \to \fB_d$ be an nc-map, such that $f(0) = 0$. Let $V(1)$ be the fixed point set of $f$ on the first level. Set $V(n) \subset \fB_d(n)$ the subspace of matrices, such that their coordinates satisfy the linear relations of $V(1)$ and $V = \sqcup_{n = 1}^{\infty} V(n)$. Then $f$ fixes $V$. \[prop:fixes\_lin\_independent\_point\] Let $f \colon \fB_d \to \fB_d$ be an nc-map, such that $f(0) = 0$. If there exists a generic point $X \in \fB_d(n)$, such that $f(X) = X$, then $f(Z) = Z$, for every $Z \in \fB_d$, such that $\cL_X \subset \cL_Z$. In particular, if the coordinates of $X$ are linearly independent, i.e., $\cL_X = \{0\}$, then $f$ is the identity map. Since $f$ is nc and it fixes $X$, it is forced to fix the similarity orbit of $X$ in the ball, namely $\left(\GL_n(\C) \cdot X \right) \cap \fB_d(n)$. By Lemma \[lem:similar\_to\_coisometry\] the similarity orbit contains a point $Y$, such that $Y/\|Y\|$ is a coisometry. Note that $Y$ is also generic and $\cL_Y = \cL_X$, since the action of $\GL_n(\C)$ is linear. By [@Vig84 Corollary 4.2] we have that there exists a complex geodesic consisting of fixed points of $f$ that connects $0$ to $Y$. Since $Y/\|Y\|$ is a coisometry and thus a complex extreme point on the boundary, this geodesic is necessarily $z \mapsto z Y/\|Y\|$. Thus, in particular, the derivative of $f$ at $0$ fixes this line as well. Since $f$ is an nc map, the derivative at $0$ is $\Delta f (0,0) \otimes I_{M_n}$ and it fixes the line $z Y$. By [@3S Lemma 8.1] we have that it must fix the intersection of the matrix span of $Y$ with the ball. As above we may assume that $Y = (Y_1,\ldots, Y_{k-1},0,\ldots,0)$, with $k > 2$ and $Y_1,\ldots, Y_{k-1}$ linearly independent. By Lemma \[lem:mat-span\] the matrix span of $Y$ on level $n$ is precisely the set of all points of the form $(Z_1,\ldots,Z_{k-1},0,\ldots,0)$, i.e., $\cL_Y \subset \cL_Z$. Now as in the proof of Proposition \[prop:fixed\_level\_1\], since the $\Delta f(0,0)$ fixes the matrix span of $Y$. Applying again Lemmas \[lem:der\_fix\_coisom\] and \[lem:similar\_to\_coisometry\] and using the density of the generic points we obtain that all of the points of the form $\left(Z_1,\ldots,Z_{k-1},0,\ldots,0\right)$ are fixed by $f$. In particular, if the coordinates of $X$ are linearly independent, then the coordinates of $Y$ are linearly independent and it implies that the derivative fixes $\fB_d(n)$. By the free version of Cartan’s theorem (see [@McT16], [@Popescu10] and [@3S]). We conclude that $f$ is the identity. The above lemma is the noncommutative analog of a claim from [@Rudin] that the fixed points of a holomorphic map $f \colon \B_d \to \B_d$,

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s/30% designers/10% management. A: How should I approach both Director of Business Development and the Company Founder (we have a VERY flat hierarchy) to demand better transparency since the director's results affect my livelihood immensely? Find another job. Demand cash upfront. You've joined the company for a better work/life balance but the most likely you will be overwhelmed with various tasks and burnout just to get marginal gain to your current compensation which is already below market rate. Managers use vague language to postpone your salary increase. You're in position to think like shareholder - are you compensated in stocks or options? If you'll bring customers, how it will relate with your salary - is it specific agreement or just abstract saying? Looks contradicting: we have a VERY flat hierarchy) to demand better transparency A: I'm also new at responding, so please edit if I'm incorrectly doing this. Challenging your question here. First, my assumption: You said that management was saying your salary would go up if you directly brought in new clients, and then are saying you wish to support some new hire who's job it is to bring in new clients. Please correct if mistaken. I think its great that you wish to support this hire. That would definitely provide value and despite some odd phrasing, would match up with what you said is affecting your salary and your management should increase it. That said, I find the entire setup very suspicious. First, if you're a developer it is NOT your job to bring in new clients. Part of your job could easily be to provide a professional face when interacting with them, but you shouldn't be making sales calls and trying to bring up new business. At least, I'm assuming you aren't being paid to. However, that also doesn't mean you are entitled to know everything this new hire is doing to bring in business. Yes, you clearly have a small company, but that doesn't really matter. A marketing or sales department (whether 1 person or a whole team of 50) are their own separate entity and providing value to the company by finding new clients. I would certainly expect there to be some overlap, like if they want to market a particular phrase they would let the development team know to use specific wording, but I wouldn't expect them to seek your approval on their overall marketing strategy. To put it another way, why should you have total transparency into their job and ensuring they are 'finding new clients correctly?' If that was the case, whats to stop this Director of Business Development from demanding total transparency into YOUR work and how you're coding and interacting with clients? After all, your work results immensely impact her livelihood since if you can't provide whats stated to clients, then they'll take their business elsewhere. That sounded harsher than intended. Again, there is definite value in different teams working together to build off each other, and I encourage you to set that meeting anyways. I would just ask you instead talk about a way to share ideas / motifs/ themes to help build your company's 'brand' Let me see if I understand you correctly. You're saying the MS-8 is a "drop-in" replacement for the OEM amp, buy your interface harness and I'm done? So your harness provides all connections, including power, to the amp? If it's that simple, I gotta ask the price of the harness. I also have to ask since you appear to be a fan of staying with OEM speakers and just replacing the OEM amp, if you were to upgrade the OEM speakers, do you have any "drop-in" replacement speaker recommendations for the F25 X3? The difference is that for the F25 a center speaker input is added to the harness (F25 OEM amp is 7 channel vs the E90 OEM amp 6-channel). I do not recommend using the OEM amp 12V power source to drive the MS-8, only using a direct to battery connection for 12V. The OEM amp ground could be used for the MS-8 and it is provided at the harness. I do not have the F25 speaker measurements but I would assume that they are the standard 4" and 8" speakers, which in that case any 4" component set of less than 50mm deep would work. An 8" woofer of less than 65mm deep ("shallow" woofer) would also work (SWS-8, Jehnert XE200, Rainbow W200 X-Plain, for example). The SWS-8 is more a subwoofer than a midbass driver, the other two woofers are more of a midbass driver. Any of these woofers will require a more powerful aftermarket amplifier than the internal MS-8 amps, though.1. Introduction {#sec1} =============== Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic erosive arthritis. Inflammation in the synovium of joint and progressive damage of the bone and cartilage are the main pathological characteristics. Patients with RA mainly show joint pain, swelling, stiffness, or permanent destruction, and some of this severe damage can lead to disability and malformation or even systemic manifestation \[[@B1]\]. In the progress of RA, bone damage is an important cause of the patients\' dysfunction \[[@B2]\]. Thus, bone rebuilding is crucial in the recovery process. While in bone rebuilding, three pathways, including BMP2-Smads signal pathway, P38-MAPK pathway, and TNF-*α*/NF-*κ*B pathway, play a vital role in osteoblast proliferation and differentiation and the injury-repairing process of bone and cartilage. Iguratimod (T-614) is a new small molecule compound with anti-inflammation and immune regulation functions which has a definite disease modifying effect in an animal RA model. Some researchers report that T-614\'s effect relies on suppressing several inflammatory factors and immunoglobulin \[[@B3]--[@B5]\]. T-614 can accelerate bone formation by inhibiting osteoclast activation and promoting osteoblast differentiation \[[@B6], [@B7]\]. However, the mechanism of T-614\'s effect on promoting osteoblast differentiation is still unclear. Studies show that T-614 increases the expression of Osterix (Osx), which is a zinc-finger transcription factor that was crucial in osteoblast differentiation. Meanwhile, two signal pathways may mediate this process, the recombinant human bone morphogenetic protein-2- (BMP2-) Smads signal pathway and the P38-MAPK pathway. BMP2 induces the expression of Osx, while there are several transcription factors upstream of Osx, such as Dlx-5 and Runx2. The MAPK pathway, mediated by P38, interacts with the BMP2-Smads pathway to improve Osx phosphorylation. In addition, TNF-*α* activates the NF-*κ*B pathway to mediate inflammation. TNF/NF-*κ*B pathway participates in osteoblast proliferation, the induction of osteoblast apoptosis, the inhibition of osteoblast differentiation, and the suppression of matrix proteins. In this study, we investigated the effect of T-614 on the osteogenesis process. We first tested the content of some osteogenesis markers, such as type I collagen (Col I), bone gla protein (BGP), the contents and activity of alkaline phosphatase (ALP), and calcium nodule formation in the mesenchymal stem cells to help to verify its effectiveness and function in promoting osteoblastic differentiation. Then, we aimed to assess T-614\'s effect on Dlx5 and P38, which are involved in two pathways of osteoblast differentiation. We also intended to investigate whether T-614 inhibits the TNF-*α*/NF-*κ*B pathway. 2. Materials and Methods {#sec2} ======================== 2.1. Cell Culture {#sec2.1} ----------------- Mesenchymal stem cells (MSC) were isolated from murine bone marrow according to \[[@B8]\]. The cells were cultured in *α*-minimum essential medium (*α*-MEM; Invitrogen) supplemented with 10% fetal bovine serum (FBS; Equitech-Bio, Kerrville, TX) and bFGF (PeproTech) at 37°C in a humidified 5% CO2 incubator for several cycles. For each assay, MSCs were plated at 1 × 10^4^ cells/cm^2^, and various concentrations of T-614 were added with or without rhBMP-2 (Genetics Institute, Cambridge, MA). 2.2. ALP Content and Activity Detection {#sec2.2} --------------------------------------- MSCs were treated with rhBMP-2 and/or T-614 for 3 days. For ALP staining, the cells were fixed for 15 min with 3.7% formaldehyde at room temperature after washing with phosphate-buffered saline (PBS). Then, the cells were tested for ALP content by using an ALP staining kit (Nanjing Jiancheng Science and Technology Ltd., China) according to the manufacturer\'s instruction. To measure the ALP activity, the cells were washed twice with PBS and lysed in M-PER Mammalian Protein Extraction Reagent (Pierce, Rockford, IL) following the manufacturer\'s protocol. ALP activity was assayed using p-nitrophenylphosphate as a substrate by the Alkaline Phosphatase Test (Beyotime Biotechnology, China), and the protein content was measured using a bicinchoninic acid (BCA) protein assay kit (Pierce). ALP activity was calculated as the total activity units/the total protein concentration. 2.

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such a context, while both still continue to exist, function, and incorporate these age-old game elements in a meaningful and rational way.</p> <p>So there you go. I hope this was at least somewhat interesting and gives a taste of the familiar-but-different game world that is the Lost Lands.</p> <p>Greg</p> <p>P.S. If you haven't seen our latest Lost Lands product's Kickstarter, head over and check it out. Only 3 days to go!!</p> </div></div></div>Wed, 20 May 2015 16:43:39 +0000Greg A Vaughan3065 at https://www.froggodgames.comhttps://www.froggodgames.com/blog/telling-time-lost-lands#commentsNTRPG Con Game Registration is Uphttps://www.froggodgames.com/blog/ntrpg-con-game-registration <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Opened up last night. If you're going, hurry and sign up. They tend to fill up pretty fast.</p> </div></div></div>Wed, 15 Apr 2015 15:22:51 +0000Greg A Vaughan3042 at https://www.froggodgames.comhttps://www.froggodgames.com/blog/ntrpg-con-game-registration#commentsQ: GPO Policies are not being applied I'm an inexperienced AD/GPO admin trying to setup AD and use GPO to manage my kids laptop. I can get some user policies to apply but not computer policies. I've been spinning my wheels on this for over a day trying to figure out what I've done incorrectly preventing the full GPO to be applied to the laptop. I have provided some links to the GPRESULTS from the client laptop from an elevated cmd prompt as well as the report from the server on the GPO. The scope includes: Authenticated Users; The laptop computer, and the user group for my children One of the items set in the computer is dis-allowing the MS Store to be run, since you cant disable it in Win 10 Pro. Any help that can get this GPO working would be appreciated. https://pastebin.com/ygH1fiXa - Laptop GPRESULT https://pastebin.com/aeaqDCj3 - Server Results HTML - Copy & paste into a .htm file and view in a browser A: The issue I found yesterday was that the Computer was something I had added and not one that was put into the AD by joining it to the domain. Once I looked in the default computer OU I found what was created and used that to apply the GPO against. Pigeon Simulator: Town Bird Full iOS UniversalGames Fly in sky as a pigeon in Pigeon Simulator: Town Bird, wild dove sandbox! Welcome to one of the craziest animal games! Start your pigeon survival with our dove sandbox now. We like animals and strive to make our dove game best. Feed your flock of flying animals! This survival sandbox includes a map and a guide. Choose preferable mode of the sandbox - animals survival or quests. In our survival sandbox we offer you to learn craft of animals. Flying over town as a pigeon! Maintain your pigeon energy, fly over town, fight town and wild animals for survival. Craft to levelup your animals. Finish all quests - survival in the dove sandbox can be challenging, but funny in animal games. Learn to control your animals, lead a dove flock and more. You will meet a lot of animals species in the dove sandbox. To be a good town dove, or a wild pigeon - it is up to you. Enjoy fun of dove flying and sky nature. Craft your survival strategy. Town pigeon simulator is better than real wild animals! Live the life of animals in sandbox. Complete quests and do what doves do. Find a mate and breed a new town pigeon flock. Develop a survival strategy against wild and town animals. Levelup pigeon survival skills. Or find mates and start a flock. Town quest will open new survival skills. Yourtown pigeon can die in the sandbox - survival in the sandbox is not easy for animals. Flying like a pigeon is cool! Try Pigeon Simulator: Town Bird, be a pigeon and explore a big wild world!Very important : Please look at the coments on the end with many updates You may not know thatI am a avid book reader. Since I was young I was advanced by two yeas in the high schoolreading books on maths and chemistry of the university . by the time, as student of marketing and economics and the time I was learning English language I wasreadingAmerican books of marketing advertising and public relations and nearly little later with books on sellingwhich was my favoritereading . Since then upon the times I was adding in reading to some other specialized book areas such as related to radio and electronics , food and nutrition (a subjectthat I am still interested) computer techniques and programs with some interest in photopaint etc , and till nowwith some interest in baby caring , by reading magazines and books With the advent of book searching via the net I have collected some vey interesting booksthat some of them have already been printed ….. … until IO have boughtvery recentlya e-book reader that is supposed to stop printing ! Thise reader have been boughtfrom Plaisio , a chain storeof computer systemsand peripherals sold under the name turbo xE B600 , which is the brand name of mostly OEM products from supposedly China . This e reader usesthee ink technologya property patent from E ink companyusing micro bubbles to orientate in a thin film screen Its formatis very minimalusing 4+1 navigation buttons. At the right of this picutre there ar the buttons for font sizing And hereis a picture with the buttons on the left pane : First button goes for multimendia (smething i am not interested ), lanscape mode , exit mode(frm eradding mode ) and property mode (all adjustments including status bar etc ) The company claimsthata power chargecan support ca 7000 pagesor 30 hours of button operation … Its inside memory of ca 375MBcontainsthe ebook guide in the main directoryand n separate directoryca 60 books in pdf format , which are under the public domain . Several of them are Shakespeare’s Romeo nd Juliet , Homer’s Iliad and Odyssey, The art of war and many othersand only two Greek e-books . Navigationis quite simple - the reader is normally set to being switched always on . This is in contrast to most electronic appliances m becauseonce a page is applied , no electricityrequiredto keep the bubbles in their position ! In its off condition there is still a picture on the screen - A memory slot is also available using SD cards with memories up to 4 GB, The company Plaisio suggeststo insert the SD card with the power off … -Directory listing is of 3 modes , the basic can show only the titles , the second showsthe page name and a thumbnail of thefile and the third does it on two columns This is the analytical mode THis is the landscape file mode -Directory listing also supports direct access to the flash memory and files are shown mixed with a descriptive mark on the screen. ON the above picture is this shown on the exterme right of the dir listing There is ability to sortfiles by title , by author -Opening a fileis quite simple by just pressing the [enter ]in a file . In just 1-3 seconds most files have been loaded, depending on the file size . chm fileshowever require much more time , a 3.5 MB file requires about 40 secs! Once a file is opened , there is the abilityto change the font size with the buttons located in the right part of the reader . The correct page layout can be seen using the font off or size ‘1’ . The 2nd button from the leftcan turn the view into landscape . This happens also in the dir listing. Navigation is made with the 4 buttons . Left and right up and down work correctly for the directory listings but in reading mode left/up and right/down arrows do samework . Could expect a better solution Now , testing the reader I have found several interesting and peculiar things a follows: First e ink is not 100% white . See this picture : It seems eink is 60% gray leveled comapring to the pure white -Resizing fonts (numbers 2-7 )in pdfs with layouts , destroys the format in full separating the pictures at the ‘end’ of the virtual page . Landscaping retains the format in the font off option (1) butsplits the page into two parts upper and lower. Pageswith very small upper and lower marginssuffer from truncation ….(and that’s still debating in several cases ) For example this page wit font resizing pctures beasme this way . I think that Adibe erader which is built in did this fault In most casesthe fonts this way are still quite small , atleast 4-

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7 ml/g cell wet weight) in MP2 buffer (20 mM KP~i~ pH7.4, 0.6 M sorbitol, and 3 mg/g cell wet weight zymolyase 20T \[Seikagaku Corporation\]), and incubated with shaking for 1 h at 30°C for spheroplastation. Spheroplasts were harvested (3,000 *g*, 5 min, 4°C) and resuspended (13.4 ml/g cell wet weight) in homogenization buffer (10 mM Tris, pH 7.4, 0.6 M sorbitol, 1 mM EDTA, 1 mM PMSF, and 0.2% albumin bovine fraction V, fatty acid-free \[Serva\]). The following steps were performed on ice and centrifugations were performed at 4°C. After homogenizing the spheroplast suspension twice by 10--15 strokes of a Teflon plunger in a tight fitting homogenizer (Sartorius AG), the homogenate was centrifuged at 3,000 *g* for 5 min. Centrifugation was repeated once and mitochondria were then harvested by centrifugation at 17,000 *g* for 12 min. The pellet was resuspended in SH buffer (0.6 M sorbitol and 20 mM Hepes, pH 7.4) to a final concentration of 10 mg/ml. Mitochondria were snap-frozen in liquid nitrogen. Labeling of mitochondrial translation products in vivo ------------------------------------------------------ Cells were grown on minimal medium containing 2% galactose; 20 µg/ml arginine, methionine, threonine, and tyrosine; 30 µg/ml isoleucine; 50 µg/ml phenylalanine; 100 µg/ml valine; and 0.1% glucose ([@bib27]). A cell amount corresponding to an optical density (OD~595nm~) of 0.5 was collected, washed twice with minimal medium containing 2% galactose, and incubated at 30°C for 10 min in the same buffer supplemented with 0.15 mg/ml of all amino acids except methionine. After inhibiting cytosolic protein synthesis with 0.15 mg/ml cycloheximide, labeling of mitochondrial proteins was started by the addition of 6 µCi \[^35^S\]methionine. Pulse labeling was stopped after the indicated time points by addition of lysis buffer (1.85 M NaOH and 1.1 M β-mercapto-ethanol) containing 8 mM unlabeled methionine. After incubation for 10 min on ice, proteins were precipitated with 14% TCA. The stability of mitochondrial translation products was chased by stopping a 15-min labeling reaction by the addition of 8 mM of unlabeled methionine and taking samples after the indicated time points, which were lysed and TCA precipitated. Pellets were resolved in sample buffer, subjected to SDS-PAGE on 16:0.2% acrylamide/bisacrylamide gels, and analyzed by autoradiography and Western blotting. Fractionation of mitochondrial lysates -------------------------------------- Isolated mitochondria (300 µg) were lysed for 30 min on ice in lysis buffer containing 1% digitonin, 50 mM KCl, 1× complete protease inhibitor mix, 0.5 mM MgCl~2~, and 20 mM Hepes/KOH, pH 7.4. After a clarifying spin for 10 min at 25,000 *g* at 4°C, one half of the extract was precipitated with 12% TCA (100% total, T) and the rest was under-layered with 50 µl sucrose solution (1.2 M sucrose and 20 mM Hepes/KOH pH 7.4) and centrifuged for 105 min at 200,000 *g* in a TLA100 rotor (Beckman Coulter) at 4°C. The supernatant (S) was then collected and the ribosome-containing pellet (P) was resuspended in lysis buffer. Proteins of both fractions were precipitated with 12% TCA. The resulting pellets were dissolved in sample buffer, separated by SDS-PAGE, and analyzed by Western blotting. Analysis of bc~1~ complex assembly intermediates by 1D BN PAGE and 2D BN/SDS-PAGE --------------------------------------------------------------------------------- Isolated mitochondria (250 µg) were lysed in BN PAGE solubilization buffer (1% digitonin, 50 mM NaCl, 50 mM imidazole, pH 7, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. After a clarifying spin for 10 min at 25,000 *g* at 4°C, 25% of the lysate was taken as a total and the rest was loaded onto a linear (4--13%) BN polyacrylamide gradient gel. Electrophoresis was performed at 4°C. After one third of the run, the cathode buffer (50 mM Tricine, 7.5 mM imidazole, pH unadjusted, and 0.02% Coomasie G-250) was replaced by cathode buffer B/10 (50 mM Tricine and 7.5 mM imidazole, pH unadjusted; [@bib36]). For 1D BN PAGE analysis, the gel was stained with Coomassie brilliant blue. For the 2D SDS PAGE, gel slices from the first dimension were incubated in SDS running buffer containing 1% SDS, incubated for 20 min at 37°C, and placed vertically onto a SDS polyacrylamide gel. Separated protein complexes were analyzed by Western blotting. Immunodepletion of bc~1~ complex assembly intermediates ------------------------------------------------------- Isolated mitochondria (500 µg) were lysed in solubilization buffer (1% digitonin, 50 mM KCl, 50 mM imidazole, pH 7.4, 20 mM Hepes/KOH pH 7.4, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. The lysate was cleared at 25,000 *g* at 4°C for 10 min. Antibodies against Cbp3 were incubated with protein A--Sepharose beads and added to half of the mitochondrial lysate to immunoprecipitate Cbp3-containing complexes. The unbound material (NB) as well as the other half of the lysate (T) was subjected to 2D BN/SDS-PAGE. 25% of the samples were loaded directly on the SDS-PAGE and 75% of the samples were used for the 1D BN PAGE. 2D BN/SDS-PAGE was performed as described in the previous paragraph. The bound material after the immunoprecipitation (E) was eluted from the washed beads with SDS sample buffer and analyzed by SDS PAGE. Assembly kinetics of the bc~1~ complex -------------------------------------- To facilitate the assembly of newly synthesized cytochrome *b*, nuclear encoded proteins were accumulated in mitochondria before their isolation. To this end, mitochondrial translation was blocked by adding chloramphenicol to a final concentration of 4 mg/ml to yeast cultures 2 h before isolation of mitochondria. To label mitochondrial translation products, 800 µg of chloramphenicol pretreated mitochondria were incubated in 800 µl of in organello buffer (20 mM Hepes/KOH, pH 7.4, 15 mM potassium phosphate buffer, pH 7.4, 0.6 M sorbitol, 150 mM KCl, 12.66 mM MgSO~4~, 12.15 µg/ml amino acid mix \[without Tyr, Cys, or Met\], 66.66 µM cysteine, 12.13 µg/ml tyrosine, 7.5 mM phosphoenolpyruvate, 6 mM ATP, 0.75 mM GTP, 5 mM α-Ketoglutarate, and 10 µg/ml pyruvate kinase) at 30°C. After 2 min, mitochondrial translation was initiated by adding 80 µCi \[^35^S\]methionine and stopped 5 min later by adding nonradioactive methionine to a final concentration of 10 mM and puromycin to a final concentration of 80 µM. Assembly of newly synthesized mitochondrially encoded proteins was allowed to continue at 30°C. After a chase period of 0, 5, 15, or 30 min, 25% of the initial reaction was harvested and diluted 1:5 in ice-cold SH buffer (20 mM Hepes/KOH, pH 7.4, and 0.6 M sorbitol). Mitochondria were reisolated by centrifugation at 16,000 *g* at 4°C for 10 min and lysed in 50 µl of BN PAGE solubilization buffer (1% digitonin, 50 mM NaCl, 50 mM imidazole, pH 7, 1 mM EDTA, 1 mM PMSF, 2 mM aminohexanoic acid, and 10% glycerol) for 30 min on ice. Lysates were clarified by centrifugation at 25,000 *g* for 10 min at 4°C and analyzed by 2D BN/SDS-PAGE. Miscellaneous ------------- Antibodies against Qcr7, Qcr8, and cytochrome *b* were obtained by immunizing rabbits with purified MBP-Qcr8, MBP-Qcr7, and peptide HGSSNPLGITGNLDRIPMHSYFI (amino acids 204--226 of cytochrome *b* coding sequence), respectively. The antibody against Arg8 was a gift from T. Fox (Cornell University). Signals from autoradiography or Western blotting were quantified with ImageJ software. Online supplemental material ---------------------------- Fig. S1 shows that cells carrying the *cox2::COB cob::ARG8^m^* mitochondrial genome and lacking Cbp6 show the same phenotype as the corresponding *Δcbp3* mutant. Fig. S2 shows that the 170 kD complex (intermediate I) is composed of Cbp3, Cbp6, Cbp4, and cytochrome *b*, and can be specifically depleted using an antibody against C

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of protest inspired activists across the country to join the fight to ensure that health care is a human right. And despite his deteriorating physical condition, Ady has always projected boundless joy and optimism into the world—even as the Capitol Police repeatedly took him into custody for expressing radical acts of love through nonviolent civil disobedience. Current Issue View our current issue Today, Ady is continuing to help build a powerful grassroots movement to win Medicare for All. (Senator Sanders is the author of the Medicare for All Act of 2019.) Health care is the leading issue dominating the Democratic presidential primary campaign. A veteran organizer at the Center for Popular Democracy, Ady’s ability to combine strategic organizing with tactical action is extraordinary. He has exemplified social justice work on a national level, showing a path beyond retrenchment that connects a vision of transformative justice with grassroots activism. For many of us, Ady Barkan represents the moral center of the political revolution. “Ady taught me that no matter how difficult the circumstances are, we can’t give up, because so many are counting on us,” said Linda Sarsour, cofounder of the Women’s March. “In Ady’s world, every breath is sacred and used to make this world just a little better than we found it ” Ady’s catalytic confrontation with Senator Jeff Flake made national headlines, but did not end with a viral video. Instead, it sparked what would become an urgent national discussion about health care. Ady’s story resonated across party identification and ideology, because everyone in America knows what it’s like to have a family member who is ill. Since that fateful exchange with Senator Flake on the airplane, Barkan went on to launch the Be A Hero PAC, which has raised $4.5 million to defeat Maine Senator Susan Collins in favor of a progressive candidate. As his physical condition deteriorates, Ady continues to participate in civil disobedience. He’s been arrested in the US Capitol building half a dozen times, and earlier this year, I was by his side when he testified in support of Medicare for All. I was awestruck by Ady’s bravery and ability to articulate a clear set of demands to lawmakers about an issue that affects all of us. I was also furious. Furious because our health care system has failed Ady, and so many people in America. “This moment calls on us all to become organizers,” Ady wrote last November. “To be heroes for our communities and future generations. To talk to our less political friends, neighbors, classmates, and co-workers, and to enlist them in this experiment we call American democracy.”Q: What is a momentary SPST Push Button Switch? I want to buy a switch (push button) where you press it to break the circuit and then press again to connect the circuit. I believe that this is what I'm looking for: However, I'm not entirely sure. I only want to use this for a basic circuit, and I mean really basic, so don't worry about anything there. A: SPST NO (Normally Open) Momentary switch is exactly what is inside a computer keyboard - press for on, let go for off. It sounds like you are looking for a Latching switch (works like a ballpoint pen) instead of Momentary. If you can only find one with more poles or features (DPDT) it'll do the job - just ignore the extra features. A brief look shows this from the same seller, I suspect he has others... This invention relates to a novel archway apparatus which is useful for building in wilderness areas, access roads, such as logging roads and secondary roads, over waterways such as streams and creeks, while causing little or not impact to sensitive wilderness environment. Typical road building processes in wilderness areas require the use of culverts in watershed areas to enable water to flow under the roadways built in those areas. Such culverts are typically constructed of corrugated steel pipe (CSP) or polyethylene-(HDPE) pipe. Installing these culverts requires that the creek or stream bed be disturbed or altered. This silt disruption upsets the natural habitat of the creek bed and causes harmful silt to move downstream. This can damage sensitive fish (including salmon) spawning beds. Once a culvert is installed, further problems arise. Water flowing through the confined interior of the culvert has higher than normal velocity. This occurs particularly during high water levels. Water flowing from the outlet (downstream) side of the culvert is turbulent and causes erosion in the creek bed area downstream of the culvert. Furthermore, since movement of the water through the culvert is restricted, water tends to back-up on the inlet (upstream) side of the culvert. This can cause erosion on the banks upstream of the culvert. The use of corrugated steel pipe (CSP) in building road culverts has been widespread. Such culverts rust over time, thereby causing an unnatural form of iron oxide pollution in the streams. CSP pipes are usually galvanized with zinc to reduce rusting. However, the zinc, in itself, as a natural process of erosion, releases a certain amount of zinc metal toxins to the waterways. This is in addition to the rust that is imposed on the environment after the zinc galvanization has corroded away. In many cases, old rusted CSP installations deteriorate structurally in strength to a point where they must be replaced. Replacement further disturbs the creek and stream beds. Over the years, numerous attempts have been made to avert such damage to creek and stream beds. Furthermore, there has been increasing pressure to preserve the environment and provide a managed balance between industrial and recreation use and conservation of natural resources. The Federal Department of Fisheries and Oceans (D.F.O.) and the British Columbia Ministry of Environment are in the process of changing their policy so as not to allow the replacement of CSP culverts with any product that disrupts the stream or creek beds. See a complete report of these requirements: Harper, D.J. and Quigley, J. T. 2000. No Net Loss of Fish Habitat: An Audit of Forest Road Crossings of Fish-Bearing Streams in British Columbia, 1996-1999. Canadian Technical Report of Fish and Aquatic Sciences 2319 (a 44 page report identified as CTR 2319). Alternatives such as suspended wooden trestle bridges, arches of rolled plate steel, and culverts of HDPE cut in half, and, of late, a material similar to CSP, have been used to overcome the typical problems associated with road building in environmentally sensitive areas. However, some of these alternative systems are costly and span distances are limited. Steel structures of any design suffer from the problem of rusting and thus contamination. In most cases, it is necessary to use heavy equipment for placement of the new heavy structures. This causes further disruption. The Federal Government of Canada has embarked on a program known as xe2x80x9cHarmful Alterations, Disruption or Destruction of Fish Habitatxe2x80x9d(H.A.D.D.), 1998. A search of the art reveals that different culvert attempts and designs have been published. A recent design is the use of xc2xexe2x80x3 plate steel that has been developed by Sanders and Company Contracting Ltd., sold under the trade-mark ENVIRO-PIPES. A simple calculation of the weight of xc2xdxe2x80x3 plate steel confirms that a mobile crane is required to place this plate structure in a creek bed or remove this structure from the creek bed once the road requires decommissioning. Furthermore, a structure of this size would require a low bed and truck for transport to and from the installation site. Another product on the market comprises a non-corrugated plastic arch. This arch is discussed in the December 1999 issue of Forest Engineering Research Institute of Canadaxe2x80x94Eastern Division. This product is manufactured by KWH Pipe (Canada) Ltd. and is known as the KWH Arch. This product is available to a maximum diameter of 2.3 meters. Once the pipe is cut in half, it expands to 24% larger than its original diameter. Thus the structure becomes somewhat less than half-circle. Since there are no footings along the edges that contact the ground, and with the tension placed on the structure upon installation, the product would tend to sink or be depressed into the banks of the creek bed. This therefore causes further deflection of the pipe from its original less than half circle configuration and compromises the integrity of the structure. There is a real possibility of collapse of the structure under load. A further culvert product is supplied by Armtec Construction Products. Their product is called a xe2x80x9cMini Span Bridgexe2x80x9d. The Mini Span I has a maximum width of 1800 mm. The Mini Span is brought to the site as a one-piece assembled structure. The Mini Span II is available to a width of 3660 mm, making transport of this structure difficult and costly. Required footing and structural support demands trained installers and heavy equipment for installation. This product is also made of galvanized material and other steel components that require treatment to avoid rusting. An article by Soleno Inc. in the November/December 1999 issue of the Canadian Forest Industries describes a product referred to as xe2x80x9cSolArcxe2x80x9d. Installation of the SolArc product requires 8 to 10 cubic meters of logs (one load) to use

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mean threshold of 10 and standard deviation of 2.5, correlations between pairs of thresholds obtained with 100 reversals each are relatively stable, at 0.67, 0.7, and 0.65 for our 3 lapse rate conditions. This stability in correlations across differing lapse rates happens because lapses alter the mean of the probability distribution of thresholds, but not its relative standard deviation. Checking for consistency of reversal points within a staircase run is another intuitive potential approach to identifying data with lapses. However in the same simulation for 20 reversals, the standard deviation of reversal points was 5.2, 5.4 and 5.4, respectively, providing no information about the presence of the lapses. This probably happens because the range of reversal points is not extended by these lapses but is simply shifted (0% lapses, mean range 9.9–27.2; 5% lapses, 9.9–28.4; 10% lapses, 10.6–29.4). It is worth noting that the lapse rates tested here are purposefully conservative and probably don’t represent the poorest performance that is observed in some studies with children (see, for example, the plots in McArthur & Hogben, 2012). If a participant lapses consistently over a long period during a run of trials, for example, then the effects of this may be visible in the measures tested above. However, these measures clearly do not identify participants who lapse randomly at low rates, despite the impact that these lapses have on the measured threshold estimate. The problem of lapses in psychophysical data is therefore difficult to solve in a satisfying way. An alternative approach to measuring sensory sensitivity, which bypasses the need for obtaining behavioural response from participants, is to use neurophysiological measures. Mismatched negativity (MMN) is an evoked response elicited by a change in a stimulus parameter embedded in a sequence, and which has been used to index sensory sensitivity in a range of developmental settings (Näätänen et al., 2007). The MMN response is modifiable by contributions from sources in the frontal lobes, and is sensitive to the cognitive symptoms of disorders such as schizophrenia, so although considered pre-attentive in origin it is not entirely free of cognitive influence. Bishop (2007) has provided a critical review of the use of this method in research of developmental disorders. It is also possible to construct “cortical psychometric functions” from auditory evoked responses measured with neurophysiological data, a method which shows promise for bias-free estimates of threshold (Witton et al., 2012). Yet there are challenges associated with using neuroimaging techniques with children (Witton, Furlong & Seri, 2013) and for the majority of studies, psychophysics will remain the method of choice. Developing strategies to reduce the likelihood of lapses during adaptive procedures, especially through improving task engagement by children (e.g., Abramov et al., 1984), is therefore critical—as is the use of statistical methods which are sensitive to the limitations of these procedures. Future behavioural studies taking an individual-differences approach (e.g., Talcott, Witton & Stein, 2013) can potentially help improve our understanding of the link between cognitive factors such as attention and memory, and psychophysical performance, especially if these studies make detailed estimates of psychometric functions and lapse rates. Convergent measures, especially physiological measures such as eye-movement recordings, which can monitor a child’s physical engagement with a visual stimulus, would also improve the extent to which researchers can determine the validity of individual trials. Finally, the application of neuroimaging techniques, especially those with high temporal resolution (i.e., MEG and EEG) could provide useful evidence to help unpick the cognitive processes that underpin variable task performance. Conclusions Overall, the findings from the simulations presented here suggest that the accuracy and efficiency of studies using adaptive procedures in untrained and especially paediatric populations are best maximised by very careful choice of adaptive procedure, taking into account the psychophysical properties of the task and stimulus. This should be followed by careful statistical analysis, especially when comparing groups. Investing in innovations able to improve quality time-on-task, particularly for children, in relevant studies will greatly improve data quality, if trial-numbers can be increased. Attempting to index individuals’ lapse rates, and incorporating this information into statistical analyses, would also enable researchers to account for the impact of such differences on experimental findings. Supplemental Information Theoretical convergence points determined by the adjustment rule of a staircase are based on the assumption of a cumulative normal psychometric function. When simulated using a Weibull function, the procedures converge at a very slightly lower value; the 2-down, 1-up staircase converges at 70.2% correct rather than 70.7% after 1,000 reversals. These small differences are negligible in the context of the effects described here. Acknowledgements The authors would like to thank Professor Genevieve McArthur, Dr. Nicholas Badcock, and an anonymous reviewer for their insightful comments on an earlier version of this paper. Additional Information and Declarations Competing Interests The authors declare there are no competing interests. Author Contributions Caroline Witton conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper. Joel B. Talcott conceived and designed the experiments, wrote the paper, reviewed drafts of the paper. G. Bruce Henning conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper. Report a problem Our promise PeerJ promises to address all issues as quickly and professionally as possible. We thank you in advance for your patience and understanding. Type of problem Details 500 characters remaining Follow this publication for updates "Following" is like subscribing to any updates related to a publication. These updates will appear in your home dashboard each time you visit PeerJ. You can also choose to receive updates via daily or weekly email digests. If you are following multiple publications then we will send you no more than one email per day or week based on your preferences. Note: You are now also subscribed to the subject areas of this publication and will receive updates in the daily or weekly email digests if turned on. You can add specific subject areas through your profile settings.May 11 10:25 PM PT11:25 PM MT12:25 AM CT1:25 AM ET1:25 ET5:25 GMT13:25 10:25 PM MST12:25 AM EST11:25 PM CST12:55 AM VEN9:25 UAE12:25 AM CT-Nick Wittgren did not allow a hit or walk in 2.0 scoreless innings as the Cleveland Indians lost to the Oakland Athletics 4-3 on Friday. Wittgren struck out two, ending the game with a 1.32 ERA and 0.73 WHIP on the season. May 8 6:05 PM PT7:05 PM MT8:05 PM CT9:05 PM ET21:05 ET1:05 GMT9:05 6:05 PM MST8:05 PM EST7:05 PM CST8:35 PM VEN5:05 UAE (+1)8:05 PM CT-Nick Wittgren allowed one hit without giving up a run in 1.0 inning as the Cleveland Indians defeated the Chicago White Sox 5-3 on Wednesday. Wittgren did not strike out a batter, ending the game with a 1.54 ERA and 0.86 WHIP on the season. May 6 6:16 PM PT7:16 PM MT8:16 PM CT9:16 PM ET21:16 ET1:16 GMT9:16 6:16 PM MST8:16 PM EST7:16 PM CST8:46 PM VEN5:16 UAE (+1)8:16 PM CT-Nick Wittgren allowed one run on one hit in 0.1 innings as the Cleveland Indians lost to the Chicago White Sox 9-1 on Monday. Wittgren did not strike out a batter, ending the game with a 1.69 ERA and 0.84 WHIP on the season. Apr. 14 2:45 PM PT3:45 PM MT4:45 PM CT5:45 PM ET17:45 ET21:45 GMT5:45 2:45 PM MST4:45 PM EST3:45 PM CST5:15 PM VEN1:45 UAE (+1)4:45 PM CT-Nick Wittgren did not allow a hit or walk in 1.1 scoreless innings as the Cleveland Indians lost to the Kansas City Royals 9-8 on Sunday. Wittgren did not strike out a batter, ending the game with a 0.00 ERA and 0.50 WHIP on the season. Apr. 12 8:29 PM PT9:29 PM MT10:29 PM CT11:29 PM ET23:29 ET3:29 GMT11:29 8:29 PM MST10:29 PM EST9:29 PM CST10:59 PM VEN7:29 UAE (+1)10:29 PM CT-Nick Wittgren allowed one hit without giving up a run in 1.1 innings as the Cleveland Indians lost to the Kansas City Royals 8-1 on Friday. Wittgren struck out two, ending the game with a 0.00 ERA and 0.75 WHIP on the season.Impact of Mesenteric Defect Closure During Laparoscopic Roux-en-Y Gastric Bypass (LRYGB): a Retrospective Study for a Total of 20

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5,000 mg/kg oral administration. This showed that a lethal dose of 50% is greater than 5,000 mg/kg, which attests that plant products are frequently considered to be safe and have fewer adverse effects than synthetic ones.[@CIT0037] The in vivo antiplasmodial activities of *N. Congesta* crude extract and solvent fractions were investigated by evaluating the chemosuppression during early infection, while crude extract and aqueous fraction were used to evaluate the curative activity of the plant during established infection (Rane's test). In both suppressive and curative tests, determination of percent parasitemia suppression and improved survival days are the most widely used parameters for antiplasmodial activity screening.[@CIT0031],[@CIT0032] Since 500, 750, and 1,000 mg/kg crude extract and 200, 400, and 600 mg/kg aqueous fraction showed significant parasite suppression, they were further evaluated in curative test.[@CIT0047] In the 4-day chemosuppressive and Rane's test, the highest parasitemia suppression (100%) was recorded in the group treated with positive control (chloroquine), while the lowest parasitemia suppression (0%) was recorded in the group treated with the negative control, distilled water. *N. congesta* hydromethanolic extract exhibited dose dependent parasitemia suppression and prolonged the survival days of *P. berghei* infected mice, the highest activity recorded at the maximum dose administered. This is comparable with the activities of the previous reports exhibited by *Polyalthia longifolia, Trichilia heudelotii*, and *melia azedarac*h.[@CIT0012],[@CIT0027] Parasitemia level in all extract and aqueous fraction treated groups was less than the group treated with negative controls. This revealed that extract and its aqueous fraction had a suppressive effect on the multiplication and erythrocyte infectivity of *P. berghei* parasites in mice. The hydromethanolic leaf extract of *N. congesta* suppressed parasitemia by 58.3%, the highest chemosuppression recorded from all the fractions evaluated in the current study. However, at lower concentrations (100, 200, 400 mg/kg), it exhibited insignificant activity as compared to the negative control. This could be attributable to the presence of an insufficient concentration of active principles at lower doses of the extract.[@CIT0015],[@CIT0032] The curative activities were significant at 1,000 mg/kg crude extract at day 7 and 400 and 600 mg/kg of aqueous fraction at days 5--7. Crude extract contains a collection of medicinal compounds and activities of one compound may mask the other or may be potentiated,[@CIT0032],[@CIT0046] hence, fractionation may help to eliminate potentially toxic, inactivating, and/or potentiating compounds.[@CIT0042] Aqueous fraction demonstrated dose dependant higher activity in blood parasitemia suppression against *P. berghei* than other fractions. The relatively higher activity of the aqueous fraction could be due to secondary metabolites present in crude extract which might be partitioned in the aqueous fraction.[@CIT0032],[@CIT0042] A report from the aqueous fraction of *Nuxia* species confirmed the presence of iridoid glycosides (mono terpenes),[@CIT0019] which are water soluble[@CIT0048],[@CIT0049] and have antibacterial, anti-inflammatory,[@CIT0050] antioxidant, immune modulating, and pain killing properties.[@CIT0049] These effects are highly associated with antimalarial activities.[@CIT0034],[@CIT0042],[@CIT0047] The MST is a very important parameter to evaluate the antimalarial activity of plant extracts.[@CIT0031] The aqueous fraction prolonged the survival time of *P. berghei* infected mice dose dependently. This might be due to the presence of secondary metabolites that prevent the overall pathologic effect of the parasite in the infected mice, like anti-inflammatory, antioxidant effects in addition to suppression of the parasite.[@CIT0051] N-hexane fraction did not show any parasitemia inhibition or prolongation of survival days in all dose-treated groups. On the other hand, at higher doses of the fraction the parasitemia level was increased. This could be due to loss of active constituents during fractionation[@CIT0032],[@CIT0042] or the constituents partitioned in this fraction may be immunosuppressants which can lower the immune system.[@CIT0017] The chloroform fraction did not exhibit dose dependent chemosupressive activity, efficacy diminished as the dose increased. This inconsistent effect might be attributed to constituents in the fraction which may follow different kinetics.[@CIT0052],[@CIT0053] In vivo percent mean suppression ≤90% with respect to negative control usually indicates the test compound is active.[@CIT0046] Accordingly, crude extract at 1,000 mg/kg (58.33%), aqueous fraction at 600 mg/kg (44.88%), and chloroform fraction at 200 mg/kg (15%) could be considered to be active against *P. berghei*. This activity could be attributed to a single or a combination of its secondary metabolites. Temperature and weight reduction are the hallmark of malaria infection in rodent models, indicating that an effective antimalarial agent should prevent temperature and body weight reduction in *Plasmodium* infected rodents. The dose dependent suppressive activities of the leaves of *N. congesta* crude extract and water fraction proposes that crude extract and water fraction do not have any toxic effects in experimental mice at the doses evaluated. Our acute oral toxicity study result also indicated that the plant extract was found to be safe at the maximum dose tested (5,000 mg/kg).[@CIT0038] However, tremendous body weight loss has been observed in mice treated with 400 mg/kg of n-hexane and chloroform fractions; this could be attributable to the feed intake depressing effect of metabolites and interfere with the protein digestion by saponins and tannins.[@CIT0054] Conclusion {#S0005} ========== The methanolic extract and aqueous fraction of *N. congesta* leaves have in vivo anti-malarial activities. The antimalarial activity and lack of acute toxicity is suggested to uphold the earlier claims made by the Ethiopian traditional practitioners. The authors are thankful to the University of Gondar for Funding the Study. Abbreviations {#S0006} ============= ACT, Artemisinin-based Combination Therapy; ANOVA, Analysis of Variance; OECD, Organization for Economic Cooperation and Development; IP, Intraperitoneal; MST, Mean Survival Time; PBS, Phosphate Buffered Saline; PCV, Packed cell volume; PRBCs, Packed red blood cells; RBC, red blood cell; SEM, Standard Error of Mean; SPSS, Statistical Package for the Social Sciences; WHO, World Health Organization. Ethics Approval {#S0007} =============== All the experiments were conducted in accordance with internationally accepted laboratory animal use, care, and guidelines. Ethical approval for the study was obtained from the Department of Pharmacology/University of Gondar Ethics and Research Committee, Gondar-Ethiopia (SOP4/78/09). Data Sharing Statment {#S0008} ===================== Almost all the materials and data of our study are included in the manuscript, some of the material and data will be available to other researchers upon reasonable request. Authors' Information {#S0009} ==================== Mss Melshew Fenta (MSc), University of Gondar Specialized Referral Teaching Hospital, University of Gondar, P.O.Box 196, Gondar, Ethiopia, e-mail: <[email protected]>. Author Contributions {#S0010} ==================== All authors have made substantial contributions in the conception and design, acquisition of data, analysis, and interpretation of data;All authors have made substantial contributions in drafting the article, and revising it critically for important intellectual content;All authors approved the final version the manuscript to be published;All authors have agreed on the work and have given final approval of the version to be published. Disclosure {#S0011} ========== The authors have no conflict of interest to disclose. [^1]: **Notes:** + = present, − = absent. [^2]: **Notes:** Values are presented as Mean±SEM; n=5. ^a^ compared to the negative control, ^b^ compared to the positive control. \**P*\<0.05, \*\**P*\<0.01, \*\*\**P*\<0.001. **Abbreviations:** Ex, Extract; DW, distilled water (negative control); CQ, Chloroquine (positive control); CE, crude extract. [^3]: **Notes:** Values are presented as Mean±SEM; n=5. Values are significant at *P*\<0.05, ^a^compared to the negative control, ^b^ compared to the positive control. \**P*\<0.05, \*\**P*\<0.01, \*\*\**P*\<0.001. **Abbreviations:** Fr, Fraction; DW, distilled water; 3%T80 (negative control), 3%Tween 80; CQ (positive control), chloroquine; AQF, aqueous fraction; CF, chloroform fraction; Hf, n-hexane fraction. [^4]: **Notes:** Values are presented as Mean±SEM. ^a^ compared to the negative control, ^b^ compared to the positive control. Values are significant at *P*\<0.05. \*\**P*\<0.01, \*\*\**P*\<0.001. **Abbreviations:** Ex/Fr, Extract/Fraction; CE, Cr

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://www.espncricinfo.com/magazine/content/story/137311.htmlThu, 12 Apr 2018 17:29:59A marvellous symphonyThe innuendo of the past few months must have sat heavily even on Sachin Tendulkar's those broad shoulders, and today's riposte - though lacking the amazing grace of Laxman's knock - will give him immense satisfactionhttp://www.espncricinfo.com//content/story/137309.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137309.htmlThu, 22 Mar 2018 04:04:19Tendulkar and Laxman dazzle the SCGIt could not have been a better day for Indiahttp://www.espncricinfo.com//content/story/137307.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137307.htmlTue, 20 Mar 2018 18:11:54Tendulkar and Laxman dazzle the SCGIt could not have been a better day for Indiahttp://www.espncricinfo.com/australia/content/story/137306.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137306.htmlThu, 12 Apr 2018 17:22:43Making the batsmen playAt the end of first day of the first Test of the new year, India were 284 for threehttp://www.espncricinfo.com/australia/content/story/137298.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137298.htmlThu, 12 Apr 2018 17:29:59Tendulkar's resilienceAt the end of first day of the first Test of the new year, India were 284 for threehttp://www.espncricinfo.com//content/story/137296.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137296.htmlThu, 12 Apr 2018 17:22:41'If I can stay for three hours, I can stay for three more'Just like his batting, Akash Chopra has a confidence that is not demonstrativehttp://www.espncricinfo.com//content/story/137294.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137294.htmlThu, 12 Apr 2018 17:22:42A beautiful struggleAfter the horror patch that he has been through, a sparkling century wouldn't be an appropriate signpost to better timeshttp://www.espncricinfo.com//content/story/137289.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137289.htmlThu, 12 Apr 2018 17:29:56'Indian' Australians and spilt chancesGuess who flew down to boost the confidence of the Indian cricket team before the most important Test match of their liveshttp://www.espncricinfo.com/magazine/content/story/137288.html?CMP=OTC-RSS http://www.espncricinfo.com/magazine/content/story/137288.htmlThu, 12 Apr 2018 17:29:58'Indian' Australians and spilt chancesGuess who flew down to boost the confidence of the Indian cricket team before the most important Test match of their liveshttp://www.espncricinfo.com/magazine/content/story/137287.html?CMP=OTC-RSS http://www.espncricinfo.com/magazine/content/story/137287.htmlThu, 12 Apr 2018 17:29:57Sehwag and Tendulkar prop up IndiaThe young apprentices served up a fine entrée in the final Test between Indian and Australia at the Sydney Cricket Ground, and then the modern masters got down to the task of preparing a substantial main coursehttp://www.espncricinfo.com//content/story/137282.html?CMP=OTC-RSS http://www.espncricinfo.com//content/story/137282.htmlThu, 12 Apr 2018 17:22:43Sehwag and Tendulkar prop up IndiaThe young apprentices served up a fine entrée in the final Test between Indian and Australia at the Sydney Cricket Ground, and then the modern masters got down to the task of preparing a substantial main coursehttp://www.espncricinfo.com/australia/content/story/137280.html?CMP=OTC-RSS http://www.espncricinfo.com/australia/content/story/137280.htmlThu, 12 Apr 2018 17:22:44#define _CRT_SECURE_NO_WARNINGS #include <stdio.h> #include<stdint.h> #include <Winsock2.h> // need link with Ws2_32.lib #pragma comment(lib,"ws2_32.lib") #include<pcap.h> #pragma comment(lib,"wpcap.lib") #include<memory.h> #include <stdlib.h> #include <sys/types.h> #include "data.h" #include <windows.h> #include<atlbase.h> #include<atlconv.h> #include"iphlpapi.h" #pragma comment(lib, "Iphlpapi.lib") uint8_t BroadcastAddr[6] = { 0xff, 0xff, 0xff, 0xff, 0xff, 0xff }; // 广播MAC地址,Broadcast const uint8_t MultcastAddr[6] = { 0x01, 0x80, 0xc2, 0x00, 0x00, 0x03 }; // 多播MAC地址,neareast typedef enum { REQUEST = 1, RESPONSE = 2, SUCCESS = 3, FAILURE = 4, H3CDATA = 10 } EAP_Code; typedef enum { IDENTITY = 1, NOTIFICATION = 2, MD5 = 4, AVAILABLE = 20 } EAP_Type; static int times = 20;//重复请求的次数 typedef struct setting { char device[100]; uint8_t mac[6]; }Setting; void SendStartPkt(pcap_t *handle, uint8_t localmac[6]); void GetMacFromDevice(uint8_t mac[6], const char *devicename); int GetNameMacfromDevice(uint8_t mac[6], char devicename[100]); void SendResponseIdentity(pcap_t *adhandle, const u_char *pkt_data, uint8_t localmac[6]); void SendResponseMD5(pcap_t *adhandle, const u_char *pkt_data); long file_size(char *filename); /* 回调函数，当收到每一个数据包时会被libpcap所调用 */ void packet_handler1(u_char *param, const struct pcap_pkthdr *header, const u_char *pkt_data) { struct tm *ltime; char timestr[16]; ether_header *eh; x802_header *uh; eap_header *eaph; time_t local_tv_sec; //eap数据 u_char version;//802.1x版本号 u_char type;//eap的类型0--eap,1--eapol u_short len;//eap数据包长度,包括首部 int i = 0; u_char code;//request--1,respond--2 u_char id;//数据id u_char eap_type;//1--identity,--md5-challenge,3--legacy_Nak //将地址转化为可视结构 unsigned char eh_dst[6] = {0}; //目的地址 unsigned char eh_src[6] = {0}; //源地址 /* 将时间戳转换成可识别的格式 */ local_tv_sec = header->ts.tv_sec; ltime = localtime(&local_tv_sec); strftime(timestr, sizeof timestr, "%H:%M:%S", ltime); /* 打印数据包的时间戳和长度 */ printf("%s.%.6d len:%d ", timestr, header->ts.tv_us

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Crane had handed them fossilized dinosaur excrement. Then, linking the stones to the work they were about to do [under the direction of Petraeus], Crane warned that their final work product shouldn’t simply be a polishing of old crap. He had their attention.” With this anecdote, Forrester had my attention. I tend to nod off reading most business books, not (I hope) because of my advanced age but rather because they represent polishing of old shit, shibboleths I’ve seen hundreds of time before. There was no nodding off as I absorbed the way-out-of-the-box case studies Forrester presents in a book that should be read by everyone in a position of power in any organization. “Consider” is a guide to reflection and consideration for decision-making in the twenty-first century. Instead of urging us to keep focused on the problem at hand, Forrester in many cases tells us to Stop Before We Screw Up, or as Dr. Robert Bea drills into his Civil and Environmental Engineering students at the University of California in Berkeley: “STOP, THINK, AND DONT DO SOMETHING STUPID!” This is the warning Bea wants to dramatize what he terms the inevitable “oh shit” moments that present themselves — before an actual engineering calamity like the April 2010 Deepwater Horizon/BP disaster happens. Maybe it will turn out that Tokyo Electric Power Company (TEPCO), the operators of the damaged nuclear reactors in northeast Japan, made similar errors in the wake of the earthquake and tsunami of March 11. The stories and examples that Forrester presents in “Consider” demonstrate that the best decisions, insights, ideas and outcomes result when we take sufficient time to think and reflect. This seems to be an obvious rule, but the author emphasizes that our always-on wireless technology allows us to act and react more quickly than ever before. This isn’t a good thing because we are taking increasingly less time to consider our decisions before we make them. Reflection supplies an arsenal of ideas and solutions to the right problems. In addition to interviews of leaders such as Petraeus, Forrester talks to California attorney Brooksley Born, former head of the Commodity Futures Trading Commission, and Dallas, Texas-based global investor Kyle Bass, who saw the worldwide meltdown coming as early as 2005, three years before it body-slammed the world. Bass’s foresight helped make money for his clients, rather than wiping them out. Forrester shows us that taking time and giving ourselves the mental space for reflection can mean the difference between total success and total failure. I was reminded of Charles Ferguson’s Oscar-winning feature documentary, “Inside Job” as I read in “Consider” how Iceland’s economy was ruined by the nation’s headlong rush into investing in the kind of unregulated new financial products Brooksley Born warned the Clinton Administration, and particularly Treasury Secretary Robert Rubin, about, to no avail. “Inside Job” has a “cold start” beginning (starting the film before the opening credits) concentrating on Iceland’s predicament. It’s a nation of less than 400,000 people, but similar mistakes were made in Greece, Hungary, Spain and — of course– the United States. We need more people like Brooksley Born, Kyle Bass, Robert Bea, David Petraeus and the others cited and/or interviewed by Forrester in his must-read book. And we need to turn off the distracting wireless devices and do some really deep thinking. About the author Daniel Patrick Forrester is a management consultant with over fifteen years experience leading complex strategy and technology evolution engagements for senior executives from Fortune 100 and 500 companies, and federal government organizations. Current and past clients include: Verizon, Sallie-Mae, Sprint, Dow Chemical, FMC Corporation, The Department of Homeland Security, The Library of Congress, The Congressional Research Service, and the United States Marine Corps. Forrester is frequently in demand as a public speaker at organizations such as The Brookings Institute and the top-ranked Booth School of Business at the University of Chicago. He is currently a Director and Executive within Sapient Government Services, a subsidary of Sapient Corporation. Reviewed by David M. Kinchen “Wherever you are, death will find you, even in the looming tower” – from the 4th Sura of the Quran, spoken by Osama bin Laden on a videotaped speech found on a computer taken from the Hamburg, Germany al-Qaeda cell Editor’s Note: This review was originally published on Sept. 11, 2006. It is being published again to coincide with Lawrence Wright’s visit to Huntington, West Virginia on Thursday, Sept. 29, 2011. To employ the often useful – and truthful cliché – if you read only one book on Osama bin Laden, Al-Qaeda and Islamist terrorism, that book should be “The Looming Tower: Al-Qaeda and the Road to 9/11” by New Yorker writer Lawrence Wright (Knopf, 480 pages, $27.95, illustrations, sources, cast of characters, bibliography, index). About that back-of-the-book feature “Principal Characters”: It’s absolutely essential — with all the Arab names in this book – to get them straight. More books should include them, as well as the voluminous notes, sources, persons interviewed, etc. in this exceptionally well documented book that immediately joins my short list of contenders for top prize books of 2006. By telling the story of the spiritual father of bin Laden’s form of Islamism, Sayyid Qutb, who studied in Greeley, CO in 1948, Wright places fundamentalist Islam in context. Qutb was a middle-class Egyptian who was both entranced and appalled by the diversity of America, where people of various nationalities and religions seemed to get along, albeit with much literal and physical jostling. Qutb traveled widely in the U.S. and was particularly entranced – and appalled – by the vitality of New York City, in sharp contrast to the decadence of Cairo in the last days of King Farouk’s regime. After discussing Qutb’s variety of fundamentalist Islam and its influence on young Muslims of all nationalities – Qutb was hanged by Nasser in 1966 – Wright concentrates his narrative four individuals: Osama bin Laden and Ayman Zawahiri, the leaders of al-Qaeda (Arabic for “The Base”) founded in Afghanistan in 1988 in the last days of the Soviet occupation; colorful FBI Agent John O’Neill, who died in the attack on the World Trade Center five years ago and Saudi Arabia’s former head of intelligence, Prince Turki al-Faisal, who started out as ally of bin Laden and ended up as his bitter enemy after the Saudi millionaire declared jihad on the Saudi leaders. Most of the emphasis is on bin Laden and O’Neill. If there’s one thing that comes through clearly from “The Looming Tower,” it’s that the widely held belief that intelligence agencies hoard their scraps of intelligence like animals crowding around a downed prey animal, unwilling to share with anyone, is absolutely true. The rivalry between the Central Intelligence Agency and the FBI is particularly well-drawn by Wright, an indefatigable reporter and elegant writer. O’Neill, was a working class guy from Atlantic City, NJ, who loved the New York metropolitan area. He dressed like a dapper Mafia don in Burberry pin-striped suits and expensive Italian shoes – in contrast to his cheap-suit-wearing colleagues – and tried to break down this great intelligence divide, often to the annoyance of his boss, FBI Director Louis Freeh. O’Neill, who was 50 when he died in the 9/11 attacks soon after his resignation and just into his new job as security director of the WTC, is wonderfully profiled by the New Yorker writer, which makes sense since the “profile” as we know it today was invented at the magazine decades ago under the editorship of Harold Ross. At the time of the Khobar Towers bombing in August 1996, there were only seven Arabic speaking FBI agents in the entire nation, Wright notes, pointing out that the FBI was largely staffed by men of urban Irish and Italian background. One of the seven, Lebanese-American Ali Soufan, was assigned to work with O’Neill on the investigation of the USS Cole bombing; the interrogation by this loyal American of Lebanese birth of Abu Jandal in Yemen after 9/11 was instrumental in identifying the 9/11 hijackers. He now works for Rudy Giuliani’s security firm. O’Neill comes through in Wright’s narrative as one of the few intelligence officers in the nation to understand the dangers of Islamic terrorism, which really is amazing considering the events of the first attack on the World Trade Center in 1993. O’Neill, in charge of a New York-based task force dedicated to capturing Ramzi Yousef, the mastermind of the 1993 WTC attack, had to deal with general tone-deafness toward Islamic terrorism that characterized both the Clinton and Bush Administrations. Yousef was captured in 1995 and now is in prison for life. With more interagency cooperation and more leaders listening to O’Neill, his colleague and Islamism expert Dan Coleman and the CIA’s Michael Scheuer, head of that agency’s Alec Station counterterrorism agency in New York from 1996 to 1999, 9/11 could have been prevented, Wright argues. Scheuer and O’Neill, true to form, were bitter rivals, echoing the rivalry of the

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False Let d be (-16)/24*18/(-4). Suppose d*b + 313 = -185. Let g = b - -819. Is g a composite number? False Let z be -1 - 2 - (-8 - -4). Let l be 80*(z + 3 - 2). Suppose -l - 1 = -u. Is u prime? False Let h be (-2)/14 - 4/(-28). Suppose 4*f - 25 + 1 = h. Is (-4)/f*(-42)/4 a prime number? True Let z = -5680 - -8039. Is z a prime number? False Suppose 105*m - 101*m = 12. Suppose j + 5*q - 57 = 0, -2*q + 365 = 5*j + m*q. Is j a composite number? True Let h be (16/12)/(4/6). Suppose 0*r + 4 = h*r. Suppose -118 + 2 = -r*d. Is d prime? False Is (2/8)/(-17*(-12)/2659344) prime? True Let k be ((-9)/(-27))/((-1)/(-21)). Let s be k/((-21)/9) - 6. Let a(w) = -14*w + 1. Is a(s) composite? False Let m = 11056 + 2287. Is m composite? True Let f = -83665 + 149556. Is f prime? False Is (43 + -17778)/((-2)/(1*2)) a composite number? True Suppose 2*v + 3*c + 3 = 0, -3*c - 12 = v + 2*c. Is ((v - 3)/3 - 3) + 169 a composite number? True Let a = 20011 - 13058. Suppose 5*b - a = t, b + 3*t + 238 = 1635. Is b composite? True Let q(c) = 77*c + 974. Is q(69) prime? True Let b(n) = -38*n - 15. Let r be b(-12). Suppose 3*z = -9, -4*t = -7*t + 4*z + r. Is t composite? True Suppose 3*t - 19321 = 2*y, -4*y - 5968 - 13363 = -3*t. Is t a prime number? False Let f(h) = -h. Let c = 10 - 15. Let s(y) = -16*y**3 + 2*y**2 - y + 3. Let n(j) = c*f(j) + s(j). Is n(-2) composite? False Let j(s) = 3150*s + 61. Is j(4) prime? False Let m(p) = 4*p**2 + 70*p - 169. Is m(47) composite? True Suppose 10*q = 5*q + 115. Suppose -5*v + q = 3, 5*f - v - 3161 = 0. Is f composite? True Suppose 0 = -2*j + 2*p + p + 21, 4*p + 18 = j. Suppose 5518 = 8*x - j*x. Is x a prime number? False Let s be ((-12)/(-4))/(6/4). Let n be s*1/(4At SAGlobal, it’s our people who set us apart We are a community and culture of individuals who think innovatively to deliver business transformational solutions to address our clients’ toughest challenges. Whether you are looking for an opportunity to launch a career working side-by-side with a global network of highly experience talented professionals, or you want to bring years of industry expertise to bear on the next step in your professional development, SAGlobal has opportunities for you. Learn from senior consultants, who come with 14+ years of implementation experience Join us and learn from the world’s largest Dynamics pool of professionals Enhance your Dynamics implementation experience with our employees who have implemented Dynamics across more than 76 countries Our Culture We believe true culture in our company is built through Teamwork, Openness and Experience. With over 500 employees speaking over 45 languages across 25 nationalities and 18 countries, we pride ourselves on being a truly diverse organisation, combining an international footprint with in-depth knowledge on local markets. Our pervasive sense of shared values and business practices that get baked into our project execution help us feel and behave as one team across the different markets and business functions. Our success as a business depends on the success of our people. So we make sure that we create an environment where all our employees feel included and are able to perform at their best. We have a culture where success is celebrated, no matter how big or small. We trust each other and value openness and honesty in our working relationships. We help you build your career You can expect us to nurture your strengths and value your unique perspectives, and in return we expect you to share our passion for doing good. Providing our people with international experiences in line with their career aspirations, skills, experience and strengths is an important part of our development approach. We continually look for additional ways to reward our employees. Our employees enjoy competitive pay and excellent benefits, along with a positive work environment built on mutual respect and professionalism.Stereotactical fields applied in proton spot scanning mode with range shifter and collimating aperture. Some clinical indications require small fields with sharp lateral dose gradients, which is technically challenging in proton beam therapy. This holds especially true for low-range fields applied with the spot scanning technique, where large beam profiles entering from the beam-line or the insertion of range shifting blocks lead to large lateral gradients. We regard the latter case and solve it by shifting the range shifting block far upstream in conjunction with a collimating aperture close to the patient. The experiments of the current work are based on a commercial proton therapy treatment head designed for several delivery modes. In a research environment of the spot-scanning delivery mode a range shifter is inserted downstream of the scanning magnets in a slot which is usually employed only in a scattering delivery mode. This configuration is motivated by equations assuming a simple model of proton transport. In the experiments lateral dose planes are acquired with a scintillation screen and radiochromic films. Dose distributions are calculated with the Monte Carlo dose engine of the RayStation treatment planning system. We demonstrate that proton fields with 80%-20% lateral dose fall-off values between 1.4 mm and 4.0 mm can be achieved for water equivalent depths between 0 cm and 10 cm. The simulated lateral dose profiles agree with the experimental dose profiles. The sharpening of the field edges is set off by a broadening of the proton spots towards the center of the fields. This limits the clinical application mainly to small fields for which the distal and proximal conformality is of minor importance.The 3 night New Edition Story was produce well and shared very private events in the group’s life. The rollercoaster ride starts with the infamous Home Again fight and ends with the BET 25 year performance. The casting of the NE members were outstanding. The younger cast of Jahi, Tyler, Dante, Caleb, & Myles transition to the adult cast of Algee, Woody, Elijah, Kieth, and Yazz was one of my favorite scenes.The increasingly popular practice of 'vaginal seeding'—in which cesarean-delivered babies are immediately swabbed with the mother's vaginal fluids—is declared unjustified and potentially unsafe in a new critical review of scientific literature. Differences between the bacteria and other microorganisms (microbiome) in cesarean- and vaginally born babies are thought to account for the greater risk of health problems suffered by cesarean-born babies in later life. However as outlined in the study, published in Frontiers in Medicine, this difference is most likely caused by antibiotics administered to mothers delivering by C-section rather than not being exposure to vaginal microbes. Breastfeeding duration, maternal obesity and age at birth can also account for microbiome differences. "After reviewing the scientific evidence, we find no support for the 'bacterial baptism' hypothesis," says Lisa Stinson, who completed this analysis at the Division of Obstetrics and Gynecology, The University of Western Australia. "While we know that cesarean delivery impacts the infant microbiome, it's very unlikely these differences are caused by a lack of exposure to vaginal microbes at birth." Babies born by cesarean section are at greater risk of suffering from asthma, allergies, autoimmune disorders and obesity in later life, which in turn have been related to differences in a baby's microbiome—the microorganisms associated with its skin, mouth, nose and gut. "My research involves working with a lot of mothers who are delivering by C-section and some mothers show an interest in vaginal seeding after reading about it on the internet. Understandably, they want to give their babies the best start in life and on the surface this practice makes sense," Stinson explains. "But there are certain risks, such as unintentionally transferring dangerous bacteria or viruses to the newborn, so we wanted to find out if these risks were justified." Stinson performed a thorough review of research detailing bacterial populations associated with newborns, how these change from when the baby is born, and whether there were differences associated with the mode of delivery or other factors such as antibiotic administration, breastfeeding and age at birth. The story that emerged was complex: It

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) to negotiate a sale of the Properties to Purchaser, or for the Purchaser to negotiate a purchase of the Properties from the owner(s).” J.A. at 228. Appellee’s acceptance of the purported offer would have created neither a final purchase contract nor a preliminary contract requiring future negotiations. It was, at best, an invitation to commence negotiations, and such an invitation does not constitute an offer. See generally Chiapparelli v. Baker, Kellogg & Co., 169 N.E. 274, 275 (N.Y. 1929) (“Frequently negotiations for a contract are begun between parties by general expressions of willingness to enter into a bargain upon stated terms and yet the natural construction of the words and conduct of the parties is rather that they are inviting offers, or suggesting the terms of a possible future bargain than making positive offers.” (internal quotation marks and citation omitted)). Because there was no offer, Appellant’s right of first refusal was never triggered, and its claim for specific performance fails as a matter of law. Accordingly, we AFFIRM the judgment of the district court. FOR THE COURT: Catherine O’Hagan Wolfe, Clerk of Court 3 Muni was adopted by a security guard After he passed away, his wife dumped Muni back to the guard house.Muni used to live in an apartment and not familiar with outside world.I took him in since I don't think he can survive being a stray.Please help Muni by fostering or adopting.He is a friendly dog.Thank you.Related literature {#sec1} ================== For background to Schiff bases and their applications, see: Dao *et al.* (2000[@bb5]); Eltayeb & Ahmed (2005*a* [@bb6],*b* [@bb7]); Karthikeyan *et al.* (2006[@bb9]); Sriram *et al.* (2006[@bb12]). For related structures, see: Eltayeb *et al.* (2009[@bb8]); Tan & Liu (2009[@bb13]). For bond-length data, see: Allen *et al.* (1987[@bb1]). For hydrogen-bond motifs, see: Bernstein *et al.* (1995[@bb2]). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986[@bb4]). Experimental {#sec2} ============ {#sec2.1} ### Crystal data {#sec2.1.1} C~17~H~17~NO~3~*M* *~r~* = 283.32Orthorhombic,*a* = 14.719 (3) Å*b* = 9.1302 (16) Å*c* = 20.597 (4) Å*V* = 2768.0 (9) Å^3^*Z* = 8Mo *K*α radiationμ = 0.09 mm^−1^*T* = 100 K0.50 × 0.15 × 0.02 mm ### Data collection {#sec2.1.2} Bruker APEX DUO CCD area-detector diffractometerAbsorption correction: multi-scan (*SADABS*; Bruker, 2009[@bb3]) *T* ~min~ = 0.955, *T* ~max~ = 0.99816563 measured reflections4056 independent reflections2744 reflections with *I* \> 2σ(*I*)*R* ~int~ = 0.073 ### Refinement {#sec2.1.3} *R*\[*F* ^2^ \> 2σ(*F* ^2^)\] = 0.052*wR*(*F* ^2^) = 0.141*S* = 1.004056 reflections254 parametersH atoms treated by a mixture of independent and constrained refinementΔρ~max~ = 0.39 e Å^−3^Δρ~min~ = −0.29 e Å^−3^ {#d5e511} Data collection: *APEX2* (Bruker, 2009[@bb3]); cell refinement: *SAINT* (Bruker, 2009[@bb3]); data reduction: *SAINT*; program(s) used to solve structure: *SHELXTL* (Sheldrick, 2008[@bb10]); program(s) used to refine structure: *SHELXTL*; molecular graphics: *SHELXTL*; software used to prepare material for publication: *SHELXTL* and *PLATON* (Spek, 2009[@bb11]). Supplementary Material ====================== Crystal structure: contains datablocks global, I. DOI: [10.1107/S160053681000838X/ci5052sup1.cif](http://dx.doi.org/10.1107/S160053681000838X/ci5052sup1.cif) Structure factors: contains datablocks I. DOI: [10.1107/S160053681000838X/ci5052Isup2.hkl](http://dx.doi.org/10.1107/S160053681000838X/ci5052Isup2.hkl) Additional supplementary materials: [crystallographic information](http://scripts.iucr.org/cgi-bin/sendsupfiles?ci5052&file=ci5052sup0.html&mime=text/html); [3D view](http://scripts.iucr.org/cgi-bin/sendcif?ci5052sup1&Qmime=cif); [checkCIF report](http://scripts.iucr.org/cgi-bin/paper?ci5052&checkcif=yes) Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: [CI5052](http://scripts.iucr.org/cgi-bin/sendsup?ci5052)). The authors thank the Malaysian Government, the Ministry of Science, Technology and Innovation (MOSTI) and Universiti Sains Malaysia for the E-Science Fund and RU research grants (PKIMIA/613308, PKIMIA/815002, and PKIMIA/811120). NEE thanks Universiti Sains Malaysia for a post-doctoral fellowship and the International University of Africa (Sudan) for providing study leave. The authors also thank the Malaysian Government and Universiti Sains Malaysia for the Research University Golden Goose grant No. 1001/PFIZIK/811012. Comment ======= Schiff bases have received much attention because of their potential applications. Some of these compounds exhibit various pharmacological activities, as noted by their anticancer (Dao *et al.*, 2000), anti-HIV (Sriram *et al.*, 2006), antibacterial and antifungal (Karthikeyan *et al.*, 2006) properties. In addition, some of them may be used as analytical reagents for the determination of trace elements (Eltayeb & Ahmed, 2005*a*,*b*). Previously we have reported the crystal structure of 2-((*E*)-{2-\[(*E*)-2,3-dihydroxybenzylideneamino\]-5-methylphenyl}- iminiomethyl)-6-hydroxyphenolate (Eltayeb *et al.*, 2009) which exists in a zwitterionic form. The title compound is another schiff base which also crystallizes in a zwitterionic form. Herein we report its crystal structure. The title molecule exists in a *trans* configuration about the C═N double bond \[1.3129 (19) Å\], with a C6--N1--C7--C8 torsion angle of 178.13 (14)°. The molecule is slightly twisted, with the dihedral angle between the two benzene rings being 13.42 (7)°. The hydroxy group is coplanar with the attached C1--C6 benzene ring. The methoxy group is coplanar with the attached C8--C13 benzene ring \[C14---O3---C12---C11 = 2.1 (2)°; r.m.s. deviation of 0.0384 (1) Å for the eight non H atoms\]. The allyl unit (C15--C17) is in an (-)-anticlinal conformation as indicated by the C11---C10---C15---C16 torsion angle of -94.28 (18)°. An intramolecular N---H···O hydrogen bond between the NH^+^ and the phenolate O^-^ groups generate an S(6) ring motif (Fig. 1 and Table 1) (Bernstein *et al.*, 1995). The bond distances show normal values (Allen *et al.*, 1987) and are comparable with those observed in related structures (Eltayeb *et al.*, 2009; Tan & Liu, 2009). In the crystal packing (Fig. 2), molecules are linked into zigzag chains along the \[010\] by O---H···O hydrogen bonds involving hydroxy groups, phenolate and methoxy O atoms (Table 1). Within a chain, the adjacent molecules are approximately perpendicular to each other (Fig. 2). The crystal structure is further stabilized by weak intermolecular C---H···π interactions (Table 1) involving the C8--C13 ring (centroid Cg1). Experimental {#experimental} ============ The title

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}^P({\ensuremath{\Sigma_{}}}^P) \ar[d]^{P_\text{mod}} \\ \widetilde{\mathcal{M}}^B(g,n^-,n^+) \ar[rr]^{\cong} & & \widetilde{\mathcal{M}}^P(g,n^-,n^+) .}$$ The horizontal isomorphisms are given in Theorems \[MPMBiso\] and \[th:puncture\_rigged\_equiv\]. The projection maps are defined in , , , and . Checking commutativity is routine. Producing such a diagram was one of the goals of this project. It gives a full relation between the puncture and and border picture at both the moduli space and Teichmüller space levels. Before formulating a concluding theorem we need to show that $P_{\mathrm{mod}}$ is holomorphic. \[le:Pmod\] The action of $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ on $\widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ is properly discontinuous and fixed-point free. The projection $P_{\mathrm{mod}}$ is holomorphic and possesses local holomorphic sections. The bijection $\mathcal{J} : {\widetilde{T}^{B}_{\#}}({\ensuremath{\Sigma_{}}}^B) \to \widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ from Theorem \[th:puncture\_rigged\_equiv\] is a biholomorphism by the commutativity of the top triangle in Diagram and the existence of local holomorphic sections of $P_{\mathrm{DB}}$ and $P_{\mathrm{DB}}^{\#}$ (Corollaries \[riggedTPcomplex\] and \[trandtb\]). The actions of $\mathrm{DI}$ on ${\widetilde{T}^{B}_{\#}}({\ensuremath{\Sigma_{}}}^B)$ and $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ on $\widetilde{T}^P({\ensuremath{\Sigma_{}}}^P)$ can be seen to be equivalent by directly using the definitions of the actions and the isomorphism $\mathcal{J}$. The required properties of the action now follow from Corollary \[TRandMiso\] and its proof. In Lemma \[PModonriggedTP\] we showed that the action of $\mathrm{PMod}^P({\ensuremath{\Sigma_{}}}^P)$ is by biholomorphisms. Thus Proposition \[complex\_quotient\] guarantees the stated properties of $P_{\mathrm{mod}}$. \[th:resultssummary\] 1. All the spaces in Diagram are obtained from $T^B({\ensuremath{\Sigma_{}}}^B)$ by quotienting by the action of the mapping class group and certain subgroups. (Proposition \[Pmodquotient\], Theorem \[th:TBTPiso\] and Corollaries \[trandtb\] and \[TRandMiso\]. ) 2. These actions are by biholomorphisms and are properly discontinuous and fixed-point free. (Lemmas \[Modaction\_holo\], \[ModactionTP\], \[fixed-point-free\], \[propdisc\] and \[PModonriggedTP\] and Lemma \[le:Pmod\].) 3. With the complex structures inherited from $T^B({\ensuremath{\Sigma_{}}}^B)$, all the spaces in Diagram become complex Banach manifolds. (Proposition \[complex\_quotient\], Theorem \[th:complex\_moduli\], Corollaries \[riggedTPcomplex\], \[trandtb\] and \[TRandMiso\] and Lemma \[le:Pmod\].) 4. These complex structures are the unique ones that make all the maps holomorphic. All the maps possess local holomorphic sections. (Proposition \[complex\_quotient\].) 5. The horizontal bijections become biholomorphisms. (Commutativity of the diagram and existence of local holomorphic section) 6. The complex structures on the moduli spaces are independent of the choice of base surface ${\ensuremath{\Sigma_{}}}^B$ and its boundary trivialization ${\boldsymbol{\tau}}$. (Theorem \[unique\_complex\].) [Holomorphicity of Sewing]{} \[se:holo\_sewing\] As discussed in Section \[introduction\], the sewing operation is the fundamental geometric operation in conformal field theory. Holomorphicity of this operation is required in the case of chiral CFTs, or more formally, in the definition of a weakly conformal field theory. In Section \[sewing\] the sewing operation was defined for the case of quasisymmetric boundary parametrizations. We now express this operation as a map between both the rigged moduli and Teichmüller spaces. These sewing maps are shown to be holomorphic. One advantage of working with quasisymmetric maps is the conceptually satisfying way in which the sewing maps can be defined and the holomorphicity proved. Recall from Section \[Teichmuller\] that for a bordered Riemann surface, ${\ensuremath{\Sigma_{}}}^B$, the Teichmüller space $T^B({\ensuremath{\Sigma_{}}}^B)$ is endowed with the standard complex structure through the use of the Bers embedding (see [@Nag Chapter 3] or [@Lehto V.5.]). With this structure the fundamental projection $\Phi_{{\ensuremath{\Sigma_{}}}^B}: L^{\infty}_{(-1,1)}({\ensuremath{\Sigma_{}}}^B)_1 \rightarrow T^B({\ensuremath{\Sigma_{}}}^B)$ is holomorphic, and has a local holomorphic section in a neighborhood of every point. Note that the projection $P_{{\ensuremath{\Sigma_{}}}^B}: T^B({\ensuremath{\Sigma_{}}}^B) \rightarrow \widetilde{\mathcal{M}}(g,n^-.n^+)$ from can be defined by first projecting $$T^B({\ensuremath{\Sigma_{}}}^B) \to T^B({\ensuremath{\Sigma_{}}}^B) / {\mathrm{PModI}({{\ensuremath{\Sigma_{}}}^B})}$$ and following with the isomorphism $[{\ensuremath{\Sigma_{}}}^B,f,{\ensuremath{\Sigma_{1}}}^B] \mapsto [{\ensuremath{\Sigma_{1}}}^B, {\boldsymbol{\tau}} \circ f^{-1}]$ of Theorem \[TBcoversMB\]. It can be checked directly that $P_{{\ensuremath{\Sigma_{}}}^B} =P_{\mathrm{DI}} \circ P_{\mathrm{DB}^{\#}}$. From Theorem \[th:complex\_moduli\] we know that the projection $P_{{\ensuremath{\Sigma_{}}}^B}$ is holomorphic and has local holomorphic sections near every point. Actually this projection was used to induce the complex structure on $\widetilde{\mathcal{M}}(g,n^-.n^+)$. We now recall the sewing operation described in Section \[sewingoperation\]. To avoid excessive decorations, we change notation and let $X$ and $Y$ be bordered Riemann surfaces of type $(g_X, n^-_X, n^+_X)$ and $(g_Y, n^-_Y, n^+_Y)$ respectively where $n^+_X >0$ and $n^-_Y>0$. Let ${\boldsymbol{\tau}}_X = (\tau_X^1, \ldots \tau_X^{n_X})$ and ${\boldsymbol{\tau}}_Y = (\tau_Y^1, \ldots,\tau_Y^{n_Y})$ be (quasisymmetric) boundary trivializations of $X$ and $Y$ respectively (see Section \[capsewing\]). Choose $i$ and $j$ such that $\partial_i X$ is an outgoing boundary component and $\partial_j Y$ is an incoming boundary component. Let $X \#_{ij} Y$ be the sewn surface obtained by identifying $\partial_i X$ with $\partial_j Y$ using $(\tau_Y^j)^{-1} \circ J \circ \tau_X^i$. Since the choice of $i$ and $j$ is fixed throughout we simply write $X \# Y$ for $X\#_{ij}Y$. Let $\iota_X: X \to X \# Y$ and $\iota_Y: Y \to X \# Y$ be the inclusion maps. Let $g_{X\#Y} = g_X + g_Y$, $n^-_{X\#Y} = n^-_X + n^-_Y - 1$ and $n^+_{X\#Y} = n^+_X + n^+_Y -1$. The Riemann surface $X\#Y$ of type $(g_{X\#Y},n^-_{X\#Y}, n^+_{X\#Y} )$ with boundary trivialization $$\label{tau_sew} {\boldsymbol{\tau}}_{X\#Y} = (\tau_X^1,\ldots,\tau_X^{i-1},\tau_Y^{1},\ldots,\tau_Y^{j-1}, \tau_Y^{j+1},\ldots,\tau_Y^{n_Y}, \tau_X^{i+1},\ldots \tau_X^{n_X})$$ will be considered as the base surface for the Teichmüller space $T^B(X \# Y)$. There are other ways of ordering the boundary components but this issue is not important for our purposes. In conformal field theory the self-sewing operation must be considered. That is, the sewing of two boundary components of a single surface. Everything in this section can be altered without difficulty to cover this situation. We describe three sewing maps: on the level of Beltrami differentials, the level of Teichmüller space, and the level of rigged moduli space. - $\mathcal{S} : L^{\infty}_{(-1,1)}(X)_

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can Vietnam expect if your proposal for a SoutheastAsia Martime Treaty became a reality?ANSWER: The Treaty would make all ASEAN states stakeholders in maritime security.There would be more insulation for Vietnam from a unified ASEAN position. ButVietnam would have to bring its baselines in the southeast ('the pregnant lady') intoline with international law, clarify its claims, including making a distinction betweenrocks, low tide elevations and islands.Q5. How long does it take to conclude a "sensitive" treaty like the one youproposed?ANSWER: This is a ten year project at the least. But it could be the focal point forbuilding an ASEAN Political-Security Community.Q6. What are the difficulties ahead?Thayer ConsultancyABN # 65 648 097 1232ANSWER: There are certain maritime disputes that are of long-standing and some Southeast Asian attendees feel they should stay that way. Moving towards a treaty would open old wounds.Q7. What is "Vietnam's proposal for the no first use of force"?ANSWER: Vietnam has presented a proposal for ASEAN and China to agree that none of them will be the first to use force in South China Sea disputes. This would be a pledge by all parties that when an incident occurs they will exercise restraint and not resort to force. This would be an important confidence building measure.Q8. What do you mean by saying that "Vietnam would have to bring its baselines in the southeast ('the pregnant lady') into line with international law"?ANSWER: If you look at a map showing Vietnam's Exclusive Economic Zone (EEZ) there is a noticeable bulge or extension of its southeast coast to take in Tu Chinh (or Wen Anbei in Chinese). This is an excessive claim. Vietnam's Exclusive Economic Zone should be drawn from straight base lines from its coast.The bulge is referred to colloquially in Vietnamese as "the pregnant lady". When Vietnam's draft Law of the Sea went to the Politburo maritime specialists recommended bringing Vietnam's claimed EEZ into accord with international law. This was rejected on the grounds that Vietnam would have to negotiate with China sometime in future and that its excessive EEZ claim was the starting point for negotiations.Suggested citation: Carlyle A. Thayer, South China Sea: Southeast Asia Maritime Treaty,” Thayer Consultancy Background Brief, September 20, 2013. All background briefs are posted on Scribd.com (search for Thayer). To remove yourself from the mailing list type UNSUBSCRIBE in the Subject heading and hit the Reply key.Thayer Consultancy provides political analysis of current regional security issues and other research support to selected clients. Thayer Consultancy was officially registered as a small business in Australia in 2002.Background BriefSouth China Sea: China’s PeaceArk and ‘the String of Pearls’Carlyle A. ThayerSeptember 25, 2013[client name deleted]We are interested in the People’s Liberation Army Navy (PLAN) hospital ship – thePeace Ark -that has docked in Sihanoukville Autonomous Port this week. Interestingtiming, and also an interesting route the ship has been on the past four months; itsalmost a join-the-dots connecting the pearls of China's string.The Chinese military attaché here has been quoted as stating that he has neverheard of the ‘string of pearls’ and that the Peace Ark’s visit was a friendship mission.The Peace Ark stopped in Karachi, Mumbai, Thilawa Port, Chittagong and the rest.We request your assessment of the following:Q1. Why is the Chinese Navy undertaking such an operation?ANSWER: China is taking a leaf out of the U.S. naval engagement play book. The UShospital ship, USNS Mercy (T-AH-19), regularly calls in at regional ports to delivermedical and dental assistance. The US ship is staffed with American doctors andmedical specialists from the region. These visits are for good will and demonstratehumanitarian concern.The Peace Ark performs similar engagement activities for the China. Both the USNSMercy and Peace Ark gain valuable experience in working in local condition,experience that will be useful in future humanitarian assistance and disaster reliefmissions. In return, local medical personnel receive valuable experience in workingalongside foreign counterparts.Q2. What is your assessment of reports about China's interests in all these ports aspart of its "String of Pearls" or strategic bases?ANSWER: The 'string of pearls' is not a term China uses. As China's economic powerhas grown, so too has China's interest in secure sea lines of communication (SLOCs).China needs to call in at ports for to provision and for crew morale. The ports thatChina visits all belong to countries that have close economic relations with China.Contrary to speculation by strategic analysis, China had not used the ports formingthe so-called 'string of pearls' as military bases or for military purposes. The Chinesenavy does, however, make good will port visits, a normal part of naval diplomacy.Thayer ConsultancyABN # 65 648 097 1232Q3. How strong a parallel can be drawn between the route of the "Peace Ark" and the "String of Pearls"?ANSWER: The Peace Ark is visiting ports of friendly nations. This coincides with some of the ports comprising 'the string of pearls'. This is a normal component of naval diplomacy.Q4. What can China gain from such a humanitarian mission? How does it reflect on the disputes in the East and South China seas?ANSWER: China gains operational experience in foreign waters and ports, and knowledge of local medical conditions. China and the medical authorities in local ports each benefit from the exchange of knowledge and experience. Further, China gains in prestige and possibly increased influence in the countries visited.The voyage of the Peace Ark does not have a direct impact on the disputes in the East and South China Sea. But the Peace Ark's port visits do assist China in portraying itself as having humanitarian concerns. This deflects, to a limited extent, from regional concerns about the growth of Chinese naval power – the so-called China threat.Suggested citation: Carlyle A. Thayer, “South China Sea: China’s Peace Ark and ‘the String of Pearls’,” Thayer Consultancy Background Brief, September 25, 2013. All background briefs are posted on Scribd.com (search for Thayer). To remove yourself from the mailing list type UNSUBSCRIBE in the Subject heading and hit the Reply key.Thayer Consultancy provides political analysis of current regional security issues and other research support to selected clients. Thayer Consultancy was officially registered as a small business in Australia in 2002. Background BriefAustralia: ‘More Indonesia, LessGeneva’ – the New GovernmentCarlyle A. ThayerSeptember 24, 2013[client name deleted]We request your assessment of the following:Q 1. The new Australian Prime Minister, Tony Abbott, has suggested ‘moreIndonesia, less Europe’. What are the implications for Australia’s future diplomacy?ANSWER: The Abbott Government has moved quickly to align policy on foreignaffairs, defence, and economic, trade and aid issue. Prime Minister Abbott hasannounced he will give priority to visiting regional states – Indonesia, China, Japanand South Korea - before going to Washington and London.Indonesia is an emerging power whose economy is expected to overtake that ofAustralia in the decades to come. Indonesia is located to Australia’s immediatenorth and is Australia’s second closest neighbor after Papua New Guinea. It isimperative that Australia and Indonesia have the best possible bilateral relations.In practical terms, Indonesia will command priority attention. It was the mostcontentious issue in the recent national election. Some in Australia view the boatpeople as illegal migrants motivated by a desire for a better life. Others view theboat people as asylum seekers seeking safety from persecution back in their homecountries.There are two major irritants in relations with Indonesia that the new governmentseeks to address. Far and away the most important issue is boat people that stop inIndonesia on their way to Australia. The boat people are organized by criminalsyndicates of professional people-smugglers.Prime Minister Abbot has moved swiftly to assert control over Operation SovereignBorders, launched by the previous Government. Prime Minister Abbot wants to stopboats of so-called asylum seeker by turning them back. This has provoked a negativereaction in Indonesia. As a priority the Abbott government must work out anacceptable means of cooperation with Indonesia on this issue.The second irritant concerns the export of live beef to Indonesia. Last year the LaborGovernment announced the ban of live beef cattle to Indonesia after a televisiondocumentary showed cruel treatment in several of Indonesian abattoirs. TheAustralian government did not consult with Indonesia first. Indonesia retaliated byhalting imports. This year there was some negative Australian protectionist reactionThayer ConsultancyABN # 65 648 097 1232to a news report that Indonesian investors would buy a majority share in a huge cattle station and import live cattle into Indonesia. Prime Minister Abbott will have to reassure Indonesia about the reliability of Australian cattle sales.The case of Indonesia is illustrative of the Abbott Government’s greater stress on bilateral relations. Australia can also be expected to improve bilateral relations with both China and India. It is notable that both the defence and foreign ministers come from Western Australia which borders on the Indian Ocean.Q2. Australia has tried to hedge between Beijing and Washington. Do you think it is possible with Abbott's conservative nature?ANSWER: IMany Australian would not accept the premise of your question. Hedging refers to the strategic behavior of a country vis-à-

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The big engine on the plane would then propel it through air for several minutes. For the complete script, visit https://www.prageru.com/videos/why-private-investment-works-govt-investment-doesnt 6:18 Business plan of 2 crore with 30% subsidy by poultry depart Business plan of 2 crore with 30% subsidy by poultry depart Business plan of 2 crore with 30% subsidy by poultry depart published on 14 august 2017 in this video you can know about poultry schemes. the project cost is around 2 crore rupees and government providing 30 % subsidy. this scheme is for all indian and foreign countries peoples. to know more about it pls visit www.animalhusb.up.nic.in disclaimer this is not a promotional or paid video. it is only for education purpose and make awareness about govt. schemes. channel doesn't guarantee any income or profit from any crop or business idea. before choosing any plans who told in channels video please consult with any expert first because I am not an expert. information providing carefully but may be possibility of mistake . 3:30 Sir Humphrey and Jim Hacker discuss art subsidies Sir Humphrey and Jim Hacker discuss art subsidies Sir Humphrey and Jim Hacker discuss art subsidies Subsidy withdrawals and tax hikes push up prices (23 Jan 2018) LEADIN: The Jordanian government has announced new economic measures to generate hundreds of millions of dollars in revenue in 2018. But there are fears that scrapping subsidies and raising taxes will push more people into poverty. STORYLINE: There's plenty on sale in Amman's downtown market. But shoppers are braced for price rises. The Jordanian government has announced new economic measures which lift subsidies and cancel sales tax exemptions on a range of goods. Today (17 January), the tax on carbonated drinks is rising by 10 to 20 percent, Octane 95 and 98 gasoline by 30 percent and packets of cigarettes will cost an extra 0.20 Jordanian dinars (0.3 US dollars). From 1 February, the bread subsidy will also be lifted. Furthermore, the government is imposing charges of 500 to 1,500 dinars (700 to 2,100 US dollars) on imported cars, depending on their weight, while vehicle ownership transfer fess will be reduced by 30 dinars to 200. According to the cabinet, the total revenue expected from these measures will amount to 540 million Jordanian dinars (760 million US dollars). But analysts warn of serious consequences for citizens. "They will face more pressure to decrease expenses, and to reduce trade and economic activities," says economic analyst Hossam Ayyash. He says there could be an "increase of poverty" which will lead to problems with "civil and social peace". The Jordanian government has set aside funds to help the poorest cope with price rises. To qualify for the subsidy, a household's annual income must be less than 12,000 dinars (16,900 US dollars). For individuals, the limit is 6,000 dinars. So far, 230,000 families have signed up for the assistance. Beneficiaries of this National Aid Fund, will receive a cash subsidy of 33 dinars, while children of Jordanian women married to non-Jordanians and Gazans living in the kingdom will receive a subsidy of 27 dinars, if eligible. The government said that 6.2 million Jordanians will benefit from the cash support. But Amman resident Hiba Dobaoud says everyone is feeling the financial squeeze from the economic measures. "All the people are suffering, all the people are complaining, no one is happy, the effect: everyone is angry," she says. "Before we used to say that no one dies from starvation, but unfortunately now people will die from starvation." The sale tax on essential commodities will remain unchanged. Staples goods such as rice, sugar, flour, bulgur, cooking oil, meat, chicken, fish, fresh and powdered milk, eggs and tea will not see any hike in taxation. Goods such as school supplies, orthopaedic devices, sensory assistance equipment, pesticides, fertilisers and veterinary medicines will not see a rise in taxation either. The government also decided to include all senior citizens above 60-years-old in the health care insurance system and to raise the minimum wage from 190 to 200 dinars. These measures were taken as part of a larger governmental fiscal and economic reform to secure financial stability and stimulate the country's economic growth. You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/86fb76d40006b565c8b98b7d776d0e9f Find out more about AP Archive: http://www.aparchive.com/HowWeWork Buy Webcam I used for this video : https://goo.gl/3nrzy9 Buy Microphone I used for this video : https://goo.gl/jhgJeD Loan to BuildCold Storage | Get upto 50% Subsidy on Cold Storage | SBI Cold Storage Loan Link to NHB site : http://nhb.gov.in/coldstorage_scheme_guideline.aspx?enc=3ZOO8K5CzcdC/Yq6HcdIxGnFC+VjFQvFstMfkdm4FxM= 7:11 Fisheries Economics & Policy: Subsidies and Taxes Fisheries Economics & Policy: Subsidies and Taxes Fisheries Economics & Policy: Subsidies and Taxes This video is a part of Conservation Strategy Fund's collection of environmental economic lessons and was made possible thanks to the support of the Gordon and Betty Moore Foundation and the Marcia BradyTuckerFoundation. This series is for individuals who want to learn - or review - the basic economics of conservation. This video looks at subsidies and taxes in the fishery industry and how it effects the fisherman's incentives. The Fisheries Economics & Policy series will cover management strategies to preserve fishing in the long term and will include concepts such as open access, common pool resources, tragedy of the commons, maximum economic yield, taxes and subsidies, reducing effort, territorial use rights, transferable quotas and externalities. To follow this series, subscribe to our YouTube channel. For more information on these and other trainings from Conservation Strategy Fund, check out: http://www.conservation-strategy.org/ For copyright information on all sound effects, see http://www.conservation-strategy.org/en/page/csf-economic-video-lessons-sound-references subsidy fund (majaa drama) Public Housing Operating Fund Subsidy This presentation covers the 2014 Public Housing Operating Fund program funding process. An overview will be provided of the guidance notice, "Public Housing Operating Subsidy Eligibility Calculations for Calendar Year 2014." Additionally, an description of highlights and changes to the funding data collection process will be discussed. Agenda: I. Introduction and Overview of Presentation II. Highlights of Processing Notice for 2014 III. 2014 Operating Fund Subsidy Process published: 16 Aug 2013 Subsidies Explained in One Minute A one-minute video which explains what a subsidy is and refers to situations in which subsidies benefit society as a whole as well as to situations in which using them isn't exactly fair. Please like, comment and subscribe if you've enjoyed the video. To support the channel, give me a minute (see what I did there?) of your time by visiting OneMinuteEconomics.com and reading my message. Learn about interest subsidy on home loan or Home Loan Subsidy in this video. To give a boost to the mission of 'Housing for All by 2022' and also address the urban poor's housing requirement, the Pradhan Mantri Awas Yojana (PMAY) is being reworked. Of the four verticals of the scheme, 'Promotion of affordable housing for weaker section through credit linked subsidy' is the one that would appeal to the urbanites the most. There are two important changes being made to the scheme. First, while the existing guidelines are aimed at the economically weaker section (EWS) and the lower income group (LIG) category, earning Rs 3 lakh and Rs 6 lakh per annum respectively, two new subsidy slabs (yet to be notified) will bring in people earning up to Rs 12 lakh and Rs 18 lakh per annum into the fold... published: 17 Feb 2017 Why Private Investment Works & Govt. Investment Doesn't From transportation to energy, and everything in between, should the government invest money in as many promising projects as possible? Or would that actually doom many of those ventures to failure? Burt Folsom, historian and professor at Hillsdale College, answers those questions by drawing on the fascinating history of the race to build America's railroads and airplanes. Donate today to PragerU! http://l.prageru.com/2ylo1Yt Joining PragerU is free! Sign up now to get all our videos as soon as they're released. http://prageru.com/signup Download Pragerpedia on your iPhone or Android! Thousands of sources and facts at your fingertips. iPhone: http://l

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The impressive architecture did nothing to alleviate the stark quality of life, however. The streets were crowded, fear hung heavy. We often didn't have enough food, and it was the same food all the time. Plus, there were long lines out of each store. I waited with my parents, my sisters, for hours in line, it seemed like every day, and sometimes we'd get to the head of the line and there would be no more bread, or dumplings, or chicken, or whatever we had been waiting for. There were many things going on that I didn't understand. My parents' friends—other professors, artists, writers, musicians, doctors, scientists—were over all the time. They brought the food they had: chicken soup, potato cakes, Olivier salad, lamb dumplings, pickles, sauerkraut, braised cabbage, rye bread, sweet beets. My mother added a spice here, salt there, and somehow made it better. Everyone said so. They talked and laughed and argued around our wood table. And they whispered. "Hush ... quiet ... let me tell you, tell no one ... we need higher wages ... voting ... free elections ... religious freedom ... you must be careful, you must stop talking so much, Alexei ... You, too, Svetlana ... the time is not right for protesting ... still dangerous ... don't trust the government ... you are being watched ... they are listening ... the newspapers, simply an extension of the government ... propaganda on television, always they lie to us ... it's not safe for us ... no one knows what happened to Professor Popov ... to the priest ... to his brother ..." We were told, my sisters and I, not to talk about what we heard around that table. Our parents were, officially, members of the Communist Party. It was be a member or live a life of destitution with few job or educational opportunities. But we were secret Christians. In the Communist Party there was no God, no Jesus, no faith, no Christianity allowed. Had anyone known, my parents would have lost their jobs at the university. We would have been moved out of our apartment. My parents would have been able to find only low-paying jobs in a factory, if that. They might have lost custody of us or been sent to an insane asylum. Schools were state run and promoted and taught atheism. There were Russian Orthodox churches, more steeped in tradition, song, ritual, and liturgy, than God. In fact the KGB had infiltrated the Russian Orthodox church. They pretended to be priests and took confession. The Communist Party had demolished or closed thousands of mosques, temples, and churches over the years. We held church services in our home, with my uncles and their families. My mother's parents, Lada and Anatoly, came, as did my father's parents, Konstantin and Ekaterina, all loving people. My grandparents had known each other for decades. As kids, Valeria, Elvira, and I could smell fear around our family's wood table, as well as our mother's sugar-sprinkled pancakes. We could smell people's pervading sense of distrust and hatred toward the government, alongside her baked cinnamon apples. It was a government steeped in corruption, cronyism, spying, paranoia, and violence. Suspicion and obsession with possible dissidents ran high. The television was used for propaganda, the press controlled. The KGB peered into everyone's lives, and chased down and jailed without justice. The economy was stagnating, the government owned everything, the wages were pathetic, and a battle waged each day to buy enough food. Moscow, along with the rest of the Soviet Union, was suffocating and suffering. Life was too hard. But I was a child. I had loving parents who protected me from all they could. My mother and grandmothers taught my sisters and me to cook and sew. We loved to sit with them and sew small pillows using scraps of silk, cotton, even burlap. We lined them with rickrack, lace, or ruffled edges, or we embroidered flowers. We were taught to make our stitches precise, tight, and to use different stitches for different designs. Plus, I had my sisters who I could now and then hear in my head through my widow's peak, the Sabonis gift coming down the generation to me. We had friends. We played outside, bundled in coats. We went to school in uniform, with strict teachers, and we were called Oktyabrenok—October children, in reference to the revolution in October 1917. We were to behave well and study hard and memorize the party lines and songs and when we were older, we could become Young Pioneers, and wear the red scarf of the Communist Party. We did what they told us to do. We tried to ignore that tingling, black, confusing shadow that swirled around us, the hushed voices, the unexplained tears from our mother, and our father's tight face. We let it flow over our small shoulders. Then it all changed. * * * On Sunday I went over to my parents' home for dinner. My mother was babysitting Ailani and Koa because Valerie had work to do for her upcoming trial and Kai had a late shift. She was outside playing with Koa, who was dressed as a white monster, while Ailani and I cut out sugar cookies on the train station table. Ailani is in fifth grade. She has long black hair and likes to talk to her mother about crime and court proceedings. She said that school was sometimes "boring" and that she got in trouble when she made a speech recently. "Oh, uh." I could hardly wait to hear the topic. "What kind of trouble?" Ailani's forehead furrowed as she pressed the rolling pin down on the dough. "Not bad trouble. The teacher, Mrs. Phillips, said we all had to stand and talk for one minute. A lot of the kids were scared to be up in front of the class. Like they were afraid of getting bullied or something. I wasn't scared, because I knew what I was going to talk about." "Which was?" "Defensive wounds." Oh, my Lord. "A fascinating topic for a fifth grader." "Yes!" She grinned at me and picked up a flower cookie cutter. "You get it, Aunt Toni, I knew you would. You know what defensive wounds are, right?" I sure did. "I also told the whole class how to defend themselves against a kidnapper—poke out his eyes, bite his hand, smash his face up, stomp on his inner foot, scream your head off. I showed them how to put their weight on their left foot and bring their right foot up superhard into the man's nuts, and all the kids practiced kicking a kidnapper in the privates and poking out his eyes and then I had crime photos that I ... uh ... I ... uh ... borrowed from Mom ..." "Like for props?" "Yes!" Way to go, Aunt Toni! Ailani smiled. Then she frowned. "That's when I got into trouble. The teacher said the photos weren't appropriate. I hate that word: appropriate. But I said you don't want to end up dead like this, and the teacher said no more photos. Some of the kids said they were scared, and a boy started to cry." Whew. Well, that's our Ailani. I picked up a cookie cutter. It was a four-leaf clover. "Then I wanted to talk to the kids about how to get out of the trunk of a car if they got kidnapped, but the teacher said I had run out of time. She looked kinda tired." Ailani's face was confounded. She frowned, then she smiled. "But I think I'm getting an A because it's important to know about defensive wounds and how to escape from kidnappers, right?" I hardly knew what to say. My mother opened the door to the backyard, and Koa toddled in. "Hey, Koa!" Ailani bent down and hugged Koa the monster, then said, "He tried to eat my lizard today." "You tried to eat a lizard today, Koa?" I clamped my lips together and tried not to laugh. He smiled at me, not a lot of teeth. "I eat lizard." I brushed the hair back from his cowlick. "No, don't. They don't taste good." "Taste good." He giggled. "You need a lid that he can't lift off the lizard aquarium, Ailani." "I know. Mom's getting it." "If you don't, Mr. Grins here is going to eat him for lunch." "Brass knuckles," she said, rolling out more cookie dough. "What?" "The lizard's name is Brass Knuckles. You know. The weapon." "Yes, I know." "And I named my new goldfish, too." "I can hardly wait to hear their names." "Nunchucks and You're Arrested." "You have a lot going on in your head, don't you?" "Yes, I do. Sometimes it's too much and I have to lay my

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.App.3d 567, 573, 154 Cal.Rptr. 243, 246 (1979) (upholding statute). See also Mass.Gen.Laws Ann. ch. 229, 2 (West Cum.Supp.1980) (railroad not liable in wrongful death for negligence where decedent violated rules of carrier). [2] It is important to keep in mind that ad hoc application of 339 is not equivalent to evaluating child trespasser cases under the standard of "reasonable care to be exercised under all the circumstances," Blumenthal v. Cairo Hotel Corp., D.C.App., 256 A.2d 400, 402 (1969), which this court applies to invitees. See D.C. Transit System, Inc. v. Carney, D.C.App., 254 A.2d 402 (1969). Because of Firfer v. United States, 93 U.S.App.D.C. 216, 219, 208 F.2d 524, 528 (1953), there is a presumption that a trespasser assumes the risk of coming onto the property. That presumption, of course, is conclusive as to an adult, whereas it is rebuttable by a child. A child, however, has the burden to prove under 339(c) that he did not appreciate (and thus assume) the risk in coming onto the property. Beard, supra, 4 Cal.App.3d at 136, 84 Cal.Rptr. at 454. Similarly, the child has the burden under 339(d) and (e) to prove the feasibility of eliminating the danger or otherwise protecting children. Id. Accordingly, even though a child trespasser is not automatically barred from recovery, he must, because of Firfer, supra, carry a burden of proof which an invitee would not. The situation would be different, of course, if we were to abandon Firfer, supra, in favor of a single standard of reasonable care under the circumstances. See Blumenthal, supra at 402; Carney, supra, at 403; Smith v. Arbaugh's Restaurant, Inc., 152 U.S.App.D.C. 86, 96, 469 F.2d 97, 107 (1972), cert. denied, 412 U.S. 939, 93 S.Ct. 2774, 37 L.Ed.2d 399 (1973); Rowland v. Christian, 69 Cal.2d 108, 117, 70 Cal.Rptr. 97, 104, 443 P.2d 561, 568 (1968) (en banc); Mile High Fence Co. v. Radovich, 175 Colo. 537, 548, 489 P.2d 308, 314 (1971) (en banc); Pickard v. City & County of Honolulu, 51 Haw. 134, 135, 452 P.2d 445, 446 (1969); Ouellette v. Blanchard, 116 N.H. 552, 557, 364 A.2d 631, 634 (1976); Basso v. Miller, 40 N.Y.2d 233, 241, 386 N.Y.S.2d 564-568, 352 N.E.2d 868, 872 (1976); Mariorenzi v. Joseph DiPonte, Inc., 114 R.I. 294, 307, 333 A.2d 127, 133 (1975). See generally Comment, The Common Law Tort Liability of Owners and Occupiers of Land: A Trap for the Unwary, 36 Md.L.Rev. 816 (1977). I am reluctant to reconsider Firfer, supra, until we are presented a more typical case, perhaps involving an adult trespasser. See Soule v. Massachusetts Electric Co., Mass., 390 N.E.2d 716, 721 (1979). [3] Penn Central's situation is different. I would affirm the grant of summary judgment. Appellants did not file a Rule 12-I(k) statement controverting Penn Central's statement of material facts or setting forth any other genuine issue of material fact. It is therefore undisputed that appellant's injury occurred on the B & O right-of-way and was not caused by a Penn Central train. Thus, the only possible basis for Penn Central liability would be a breach of duty to help protect child trespassers against injury from a B & O train (or any other train) on B & O property contiguous to Penn Central tracks where appellant may have been playing. Given six contiguous, parallel tracksÔÇöthree B & O, then three Penn CentralÔÇöit would be logical to conclude that any duty to child trespassers should be the railroads' joint responsibility. Absent a barrier between parallel track properties, it is arguably as foreseeable that a child with easy access to Penn Central tracks will be injured by a B & O train a few yards away as it is that a Penn Central train will strike the child. On the other hand, the law is well established, at least in other contexts, that a possessor of land does not have a duty to protect someone on his property against a dangerous condition on adjacent propertyÔÇöfor example, by fencing. Cousins v. Yaeger, 394 F.Supp. 595, 604-05 (E.D.Pa.1975); Villani v. Wilmington Housing Authority, 48 Del. 450, 453, 106 A.2d 211, 213 (1954); Corcoran v. City of San Mateo, 122 Cal.App.2d 355, 358, 265 P.2d 102, 104 (1953); see Jones v. United States, 241 F.2d 26, 28-29 (4th Cir.1957). A California appellate court, in fact, has acknowledged this rule in the present context, though without much elaboration, noting that a railroad did not have a duty to protect against injury on the nearby track of another. Gutirrez, supra 174 Cal.App.2d at 870-71, 345 P.2d at 328. I would not find such a duty here, for it would require standards especially difficult to formulate and apply. In the first place, assuming a potential joint duty, it is not clear how to define and evaluate whether the two railroads' tracks are physically so close to one another that one railroad could not, as a practical matter, be expected to bear responsibility alone for protecting wayward children against entry. Second, the implications of one railroad's refusing to cooperate are unclear. Third, proximate cause problems would be compounded by the possibility that one railroad would face liability for injury to a child by another railroad on the other's own right-of-way. 411 Mass. 788 (1992) 586 N.E.2d 3 ANN M. SHAHZADE vs. C.J. MABARDY, INC. Supreme Judicial Court of Massachusetts, Middlesex. October 7, 1991. February 13, 1992. Present: LIACOS, C.J., WILKINS, LYNCH, O'CONNOR, & GREANEY, JJ. Richard T. Corbett for the defendant. Richard d'A. Belin for the plaintiff. LIACOS, C.J. This is a personal injury action arising out of an automobile accident involving the plaintiff, Ann M. Shahzade, and an employee of the defendant corporation, *789 C.J. Mabardy, Inc.[1] The case was tried to a jury which returned a verdict for the plaintiff in the amount of $300,000. After a motion for a new trial was denied, the defendant appealed to the Appeals Court. We transferred the case to this court on our own motion. The defendant argues the trial judge failed to conduct an impartial trial, and that he erred in refusing to instruct the jury "on the issue of plaintiff's comparative negligence, both as a result of her sudden stopping of her vehicle and her failure to use a seat belt." We affirm. In November, 1984, the plaintiff was stopped in a line of traffic approaching a stop sign at the intersection of Cross Street and Lake Street in Belmont, when her automobile was hit from behind by a pickup truck owned by the defendant and driven by the defendant's employee, Joseph Murphy. The parties differ slightly in their accounts of the events immediately preceding the accident. The plaintiff testified that she had stopped and waited in the line of traffic before she was hit unexpectedly from behind. Murphy testified that he and the plaintiff both had been stopped in the line of traffic, that the plaintiff proceeded and that he followed, that the plaintiff then stopped "suddenly, unexpected[ly]," and that Murphy did not have enough time to stop. Murphy estimated that he was travelling fifteen miles an hour when he struck the plaintiff's automobile. The plaintiff, who was not wearing a seat belt,[2] was thrown forward in her automobile and her head hit the steering wheel. The plaintiff was shaken but was able to drive her automobile home. Once home, she called a friend to take her to the emergency department at Choate-Symmes Hospital, where she was examined, treated, and released. *790 The next morning the plaintiff noticed that her left eye was red. She made an appointment with an ophthamologist, Dr. Paul Barsam, who determined that the plaintiff had sustained an ocular contusion, or a blow to the eye, which resulted in "edema, or swelling, like a blister" in the back of her left eye. The plaintiff subsequently developed complications in both eyes, including retinal detachment in her right eye. By the time of trial in 1989, the plaintiff had lost 40% of the vision in her right eye. Barsam testified that the

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services and accompanying documentation are comprised of "commercial computer software" and "commercial computer software documentation" as such terms are used in 48 C.F.R. 12.212 (SEPT 1995) and are provided to the Government (i) for acquisitions by or on behalf of civilian agencies, consistent with the policy set forth in 48 C.F.R. 12.212; or (ii) for acquisitions by or on behalf of units of the Department of Defense, consistent with the policies set forth in 48 C.F.R. 227.7202-1 (JUN 1995) and 227.7202-3 (JUN 1995). Unpublished rights reserved under the copyright laws of the United States. Errors and Corrections While we use reasonable efforts to include accurate and current information on our Site, we do not warrant or represent that the Site will be error-free. Data entry errors or other technical problems may sometimes result in inaccurate information being shown. 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you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. * */ #ifndef OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ #define OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ /** * @file */ /* * OMG PSM class declaration */ #include <spec/dds/sub/cond/TReadCondition.hpp> // Implementation namespace dds { namespace sub { namespace cond { template <typename DELEGATE> template <typename T> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::DataReader<T>& dr, const dds::sub::status::DataState& status) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(dr, status)) { } template <typename DELEGATE> template <typename T, typename FUN> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::DataReader<T>& dr, const dds::sub::status::DataState& status, const FUN& functor) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(dr, status, functor)) { } template <typename DELEGATE> template <typename FUN> TReadCondition<DELEGATE>::TReadCondition(const dds::sub::AnyDataReader& adr, const dds::sub::status::DataState& status, const FUN& functor) : dds::core::cond::TCondition<DELEGATE>(new DELEGATE(adr, status, functor)) { } template <typename DELEGATE> TReadCondition<DELEGATE>::~TReadCondition() { } template <typename DELEGATE> const dds::sub::status::DataState TReadCondition<DELEGATE>::state_filter() const { return this->delegate()->state_filter(); } template <typename DELEGATE> const AnyDataReader& TReadCondition<DELEGATE>::data_reader() const { return this->delegate()->data_reader(); } } } } // End of implementation #endif /* OSPL_DDS_SUB_COND_TREADCONDITION_HPP_ */ Former President Barack Obama took a thinly veiled swipe at President Trump in Indonesia Saturday, sounding the alarm about “an aggressive kind of nationalism” and grumbling about the U.S. exit from the Paris climate agreement. Obama, in a trip to his childhood home of Jakarta where he lived for four years as a boy, did not mention Trump by name but pushed back against those movements that put the national interest first. “We start seeing a rise in sectarian politics, we start seeing a rise in an aggressive kind of nationalism, we start seeing both in developed and developing countries an increased resentment about minority groups and the bad treatment of people who don’t look like us or practice the same faith as us,” he said according to the Hill. Former presidents typically do not wade into politics so quickly after they leave office, and usually stay out of the limelight so as not to step on the feet of their successor. President George W. Bush most notably went dark until well into Obama’s presidency — despite Obama frequently putting the blame of a sluggish economy at Bush’s feet. But this is the latest of a number of instances in which Obama has sought to place his footprint on the American political debate. Obama also warned that without tolerance and respect for others, then progress will dwindle in politics. “What we will see is more and more people arguing against democracy, we will see more and more people who are looking to restrict freedom of the press, and we’ll see more intolerance, more tribal divisions, more ethnic divisions, and religious divisions and more violence,” he said. According to the Hill, Obama also blasted “the temporary absence of American leadership” on climate change — a reference to the Paris climate agreement, to which Obama submitted the U.S. Trump announced last month that the U.S. would quit the deal, triggering howls of horror from liberals worldwide. “In Paris, we came together around the most ambitious agreement in history to fight climate change,” he told the audience. Earlier that day, Obama was asked about the climate deal and appeared to suggest that America may not leave the controversial climate deal after all, and bragged about how he “locked in” certain rules. “First of all, I think it’s important that even though the current U.S. administration has signaled it is going to pull out, technically it’s not out yet,” he said, according to the Guardian. “Point two is that many of the changes that we locked in during my administration continue.” Adam Shaw is a politics reporter for Breitbart News based in New York. Follow Adam on Twitter: @AdamShawNYProperty Details Property Location When you stay at El Monte Sagrado Living Resort & Spa in Taos, you'll be near the airport, within a 10-minute walk of Kit Carson Home and Museum and D.H. Lawrence Ranch. This 4-star resort is 0.5 mi (0.8 km) from Taos Center for the Arts and 0.5 mi (0.9 km) from Henningsen Fine Arts. Rooms Treat yourself to a stay in one of the 84 guestrooms, featuring fireplaces and flat-screen televisions. Your pillowtop bed comes with premium bedding. Rooms have private balconies. Wired and wireless Internet access is complimentary, while video-game consoles and satellite programming provide entertainment. Amenities Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. A spa tub and a steam room offer a relaxing way to wind down after a day on the slopes. Additional amenities at this resort include complimentary wireless Internet access, concierge services, and ski storage. Dining Grab a bite at The Gardens, one of the resort's 2 restaurants, or stay in and take advantage of the room service (during limited hours). Quench your thirst with your favorite drink at the bar/lounge. Full breakfasts are available for a fee. Business, Other Amenities Featured amenities include a 24-hour business center, limo/town car service, and express check-out. Planning an event in Taos? This resort has facilities measuring 5955 square feet (553 square meters), including conference space. Free valet parking is available onsite. Property Policies Extra-person charges may apply and vary depending on property policy. Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges. Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed. No onsite parking is available. Important Information Please note, there is important information about this property to know before you arrive. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation. Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section). You'll be asked to pay the following charges at the property: Resort fee: USD 25.00 per accommodation, per night The resort fee includes: Pool access Fitness center access Shuttle service Business center/computer access Internet access In-room safe In-room coffee Valet parking Parking Additional inclusions We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book. The following fees and deposits are charged by the property at time of service, check-in, or check-out. Breakfast fee: between USD 10 and USD 25 per person (approximately) Pet fee: USD 50 per accommodation, per day Rollaway bed fee: USD 25.00 per stay The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.Kate, right, and Trish Varnum of Cedar Rapid. Their case is behind the Iowa Supreme Court ruling on April 3, 2009, that legalized same-sex marriage in the state. / Bryon Houlgrave, The Des Moines Register by Sharyn Jackson, USA TODAY by Sharyn Jackson, USA

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ler, schenkt mir Eure Gunst":_ Max Schmeling, _Erinnerungen,_ revised and amended edition (Frankfurt a.M. and Berlin: Ullstein, 1995), p. 87. "swimming after the dollar": _Box-Sport,_ May 22,1928. "Joe Jacobs gave 'em": _Washington Post,_ May 2,1940. "If all the newspaper copy": _New York Mirror,_ June 26,1936. "It's too darned quiet": _The Boxing News,_ June 1936. "my little wife": _New York Mirror,_ October 7,1940. "Why do guys have to sleep at all?" _Ring,_ July 1940. "a New York sidewalk boy": _New York World-Telegram,_ April 26,1940. "If you hang me": _New York Sun,_ April 26,1940. "You take the big tree": _New York World-Telegram,_ June 8,1933. "triple pneumonia": _Collier's,_ July 1,1939. "The Black Uhlan of the Rhine": Schmeling, _Erinnerungen,_ p. 128. Frank Graham, among others, attributed the nickname to Damon Runyon, _New York Journal-American,_ February 6,1961. "Dempsey! Dempsey!": _Box-Sport,_ January 7,1929. "all Berlin was frantic with joy": _New York Times,_ June 29,1929. "He is quiet, modest": _New York Sun,_ June 7,1930. "an insolence": _New York World-Telegram,_ May 29,1941. "punch harder than": _Forverts,_ June 22,1930. "the fighting son of the Fatherland": _New York Daily News,_ June 13,1930. "the man on whom every American": Ibid. "paralyzed": _New York Times,_ June 14,1930. "Stay down, you idiot!": _Forverts,_ April 27,1940. "a screaming, dancing midge": _Outlook and Independent,_ July 2,1930. "You're the champion, Max!" _New York Mirror,_ June 13,1930. "as though an armored truck": _New York Journal-American,_ April 25,1940. "a severe blow": Associated Press, April 13,1930. "From the bottom of my heart": _New York Daily News,_ June 13,1930. "If anyone won": _Outlook and Independent,_ July 2,1930. "You know, that _Yacobs": New York Daily News,_ June 14,1930. "I'm sure it helped me": _Forverts,_ June 22,1930. "this unpleasant, loud-mouthed": _Angriff,_ November 25,1930. "We're on our way": _Der Abend,_ quoted in _New York World,_ June 14,1930. "a concert of boos": Rolf Nürnberg, _Die Geschichte einer Karriere_ (Berlin: Grossberliner Druckerei für Presse und Buchverlag, 1932), p. 148. "a disgrace to German": _New York Times,_ January 8,1931. "mean, impertinent, incompetent Jew": _Angriff,_ January 8,1931. "Ruthlessness was the": Nürnberg, _Die Geschichte einer Karriere,_ p. 13. "He was robbed": _New York Evening Post,_ June 22, 1932; "He was jobbed": _New York American,_ June 22,1932; "We were robbed": _New York Graphic,_ June 22,1932. "The great Sharkey-Schmeling": _New York Daily News,_ June 23,1932. "someone closing a deal": _New York World-Telegram,_ June 23,1932. "German boy of the future": Hajo Bernett, _Nationalsozialistische Leibeserziehung_ (Schorndorf bei Stuttgart: Karl Hofmann, 1966), p. 25. "There is no sport that cultivates": Adolf Hitler, _Mein Kampf_ (Munich: F. Eher Nachf., 1933), p. 453. "a German revolution of pimps, deserters": Ibid., p. 453. "the high cheek bones of an Indian": _New York Mirror,_ December 4,1937. "incapable of performing even a single knee-bend": _Angriff,_ November 6,1930. "a man from whom even his own kind turn away": Ibid., January 7,1931. "mean," "impertinent," "incompetent" Jew: Ibid., January 8,1931. "grubby" Jacobs; "spruced-up numbskull and toady": Ibid., January 7,1931. "Finally, Finally!": Ibid., April 4,1933. "Jewish capital or Jewish persons": _Box-Sport,_ April 3,1933. "a defensive action against": _Angriff,_ April 4,1933. "whatever else these blood-suckers call themselves": Ibid. "a clique of corrupt": _Box-Sport,_ April 3,1933. "Jewish big-wigs and corrupt exploiters": Ibid. "giving the cold shoulder": Ibid., April 18,1933. "If anyone over there": Schmeling, _Erinnerungen,_ p. 263. "exaggerated and untruthful": _Boxing,_ April 5,1933. "It would be paradoxical": _LAuto,_ April 2,1933. "The fact that the new, great leader of the German people": _Box-Sport,_ October 24, 1933. "the decrepit medievalism": _New York Mirror,_ March 27,1933. "We all know what would happen": _New York American,_ April 14,1933. "shame the Nazis by lying down": _New York World-Telegram,_ April 17,1933. "Delancey Street dandy": _New York Daily News,_ March 22,1935. "There are many Hebrews here": _Montreal Herald,_ April 14,1933. "He dodges embarrassing questions": _New York Sun,_ April 15,1933. "What conditions?": _New York Evening Post,_ April 14,1933. "I haff never seen Yermany": _New York Daily News,_ April 18,1933. "my friend Joe": _New York World-Telegram,_ April 14,1933. "the most popular person in Germany": _New York Evening Post,_ April 14,1933. "I tell you this—Germany is improving": _New York American,_ April 15,1933. "prices on the Boerse": _New York World-Telegram,_ April 14,1933. not to be "silly" about the man: _New York Evening Post,_ April 14,1933. "Were I to meet Baer in Germany": _New York Mirror,_ April 15,1933. MAX SCHMELING SAYS GERMANY IS NOT CRUEL TO JEWISH FOLKS: The paper is probably the _Plain Speaker_ of Hazelton, Pennsylvania. "100 percent Hitlerist": _Moment_ (Warsaw), June 11,1933. "Schmeling pulled himself": _Box-Sport,_ May 1,1933. "When I told them about the reception": Schmeling, _Erinnerungen,_ p. 266. ## Chapter Two: A Regime's Embrace "stand in defense, with clenched fist": _Box-Sport,_ April 25,1933. "to follow in his path": Ibid., May 1,1933. "The movement to make Max Schmeling suffer": _New York Mirror,_ April 21,1933. "none is so blind": Ibid., April 25,1933. "no more of a Jew-hater": Ibid., April 26,1933. "has to return to Germany some time": Ibid., April 27,1933. "I'll try to make [Max Baer] think you're to blame": _Pittsburgh Post-Gazette,_ April 18, 1933. "Shall I give them a political talk?": _Pittsburgh Press,_ April 17,1933. "We simply ignore it": _New York Times,_ April 26,1933. "Well, that's awfully nice of him": _New York Mirror,_ April 26,1933. "malicious, vitriolic, and imbecilic": _Ring,_ June 1933. "at that moment... a friend, or a lover, or something": _New York Journal-American,_ March 3,1965. "I've got a million-dollar body": _New York Times,_ November 25,1959. "Hey, Barney": Barney Ross, _No Man Stands Alone: The True Story of Barney Ross_ (Philadelphia: Lippinc

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Email ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?Email", MySqlDbType.VarChar, 100); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = email.ToLower(); return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams); } public static IDataReader GetSingleUserByLoginName(int siteId, string loginName, bool allowEmailFallback) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT * "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE SiteID = ?SiteID "); if (allowEmailFallback) { sqlCommand.Append("AND "); sqlCommand.Append("("); sqlCommand.Append("LoginName = ?LoginName "); sqlCommand.Append("OR Email = ?LoginName "); sqlCommand.Append(")"); } else { sqlCommand.Append("AND LoginName = ?LoginName "); } sqlCommand.Append(";"); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?LoginName", MySqlDbType.VarChar, 50); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = loginName; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams); } public static IDataReader GetSingleUser(int userId, int siteId) { const string sqlCommand = @" SELECT * FROM mp_Users WHERE UserID = ?UserID AND SiteID = ?SiteID;"; var arParams = new List<MySqlParameter> { new MySqlParameter("?UserID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = userId }, new MySqlParameter("?SiteID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = siteId } }; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand, arParams.ToArray() ); } public static IDataReader GetSingleUser(Guid userGuid, int siteId) { const string sqlCommand = @" SELECT * FROM mp_Users WHERE UserGuid = ?UserGuid AND SiteID = ?SiteID;"; var arParams = new List<MySqlParameter> { new MySqlParameter("?UserGuid", MySqlDbType.VarChar, 36) { Direction = ParameterDirection.Input, Value = userGuid.ToString() }, new MySqlParameter("?SiteID", MySqlDbType.Int32) { Direction = ParameterDirection.Input, Value = siteId } }; return MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand, arParams.ToArray() ); } public static Guid GetUserGuidFromOpenId( int siteId, string openIdUri) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT UserGuid "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE "); sqlCommand.Append("SiteID = ?SiteID "); sqlCommand.Append("AND OpenIDURI = ?OpenIDURI "); sqlCommand.Append(" ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?OpenIDURI", MySqlDbType.VarChar, 255); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = openIdUri; Guid userGuid = Guid.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userGuid = new Guid(reader["UserGuid"].ToString()); } } return userGuid; } public static Guid GetUserGuidFromWindowsLiveId( int siteId, string windowsLiveId) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT UserGuid "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE "); sqlCommand.Append("SiteID = ?SiteID "); sqlCommand.Append("AND WindowsLiveID = ?WindowsLiveID "); sqlCommand.Append(" ; "); MySqlParameter[] arParams = new MySqlParameter[2]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?WindowsLiveID", MySqlDbType.VarChar, 36); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = windowsLiveId; Guid userGuid = Guid.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userGuid = new Guid(reader["UserGuid"].ToString()); } } return userGuid; } public static string LoginByEmail(int siteId, string email, string password) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT Name "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append("WHERE Email = ?Email "); sqlCommand.Append("AND SiteID = ?SiteID "); sqlCommand.Append("AND IsDeleted = 0 "); sqlCommand.Append("AND Pwd = ?Password ; "); MySqlParameter[] arParams = new MySqlParameter[3]; arParams[0] = new MySqlParameter("?SiteID", MySqlDbType.Int32); arParams[0].Direction = ParameterDirection.Input; arParams[0].Value = siteId; arParams[1] = new MySqlParameter("?Email", MySqlDbType.VarChar, 100); arParams[1].Direction = ParameterDirection.Input; arParams[1].Value = email; arParams[2] = new MySqlParameter("?Password", MySqlDbType.Text); arParams[2].Direction = ParameterDirection.Input; arParams[2].Value = password; string userName = string.Empty; using (IDataReader reader = MySqlHelper.ExecuteReader( ConnectionString.GetReadConnectionString(), sqlCommand.ToString(), arParams)) { if (reader.Read()) { userName = reader["Name"].ToString(); } } return userName; } public static string Login(int siteId, string loginName, string password) { StringBuilder sqlCommand = new StringBuilder(); sqlCommand.Append("SELECT Name "); sqlCommand.Append("FROM mp_Users "); sqlCommand.Append

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't worry about it. Don't stop. Don't contemplate walking. Defeatism is not allowed. It also makes for poor time. Keep on keeping on. Think of the long-distance lorry driver and how he gets further up the road in a shorter time than the flash-car motorist that is forever pulling over to service stations. Or think of the tortoise and the hare. It is all about keeping going. Don't expect to master the art of hill climbing overnight. But if you keep at it then it will come to you. A: The gradient and length of your hill will influence how you handle it. Generally speaking it is good to maintain your momentum for as long as you can. Standing up is fine if you're intending to power up a short hill. If you're in it for a long slog, it is good to stay seated, put your hands on the flats, breath deeply and keep the upper body as relaxed as possible. Occasionally stand up and mash to break the monotony or force your cadence higher but you'll waste energy if you do it too much. It certainly is possible to be in too low of a gear (especially on a triple like you have). If you're spinning quickly and the steering is slightly wobbly, your gear is too low and you should try something higher and go faster. Rep. Alexandria Ocasio-Cortez (D-NY) suggested expanding the United States’s two party system in an interview Thursday. MSNBC’s Chuck Todd questioned the freshman congresswoman about whether her brand of Democratic socialism can appeal outside of her deep blue New York district, before probing about whether the two-party system reflects the diverse viewpoints of the country. “Do you think it would be helpful for our system if we have four or five parties?” Todd asked. The Democrat agreed. “Four or five, I think that’s fine,” she added. “It sounds like the two major parties, you feel like, don’t serve this well,” Todd followed up. “I think that it’s totally fine to say that a two party system is, especially in this time of gridlock, is sometimes a difficult thing to navigate,” she replied. “It’s a normal thing to say after these years and years and decades of gridlock. Saying, maybe something here is structurally wrong.” “I think it’s a fine conversation to have,” she added. Earlier in the interview, Ocasio-Cortez said she considers herself a capitalist, which she argued can be reconciled with her Democratic socialism. Watch above, via MSNBC. Have a tip we should know? [email protected] Star halfway across the universe was visible to naked eye for 30 secs on Wednesday - alexwg http://news.nationalgeographic.com/news/2008/03/080321-brightest-object.html ====== dhimes Those of you interested in astronomical things may enjoy <http://www.badastronomy.com/> ------ mynameishere [http://en.wikipedia.org/wiki/Gamma_ray_burst#Mass_extinction...](http://en.wikipedia.org/wiki/Gamma_ray_burst#Mass_extinction_on_Earth) ------ trekker7 Wow, this is amazing. Anybody on HN happen to see it? ------ doubleplus Halfway across the visible universe, not the entire universe, which is 90+ billion light years across. 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