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Of the following amino acids, which one is considered non-essential:
Arginine.
Histidine.
Alanine.
Chemistry
Isoleucine.
134
4
e0319c5a-3905-4c89-aa8d-2d917e5eea08
2022
The determination of creatine kinase isoenzymes in plasma is of clinical utility because:
It is a trimeric enzyme with non-specific tissue or organ distribution.
It's a dimeric enzyme with non-specific tissue or organ distribution.
It is a trimeric enzyme with specific tissue or organ distribution.
Chemistry
It is a dimeric enzyme with specific tissue and organ distribution.
135
3
3e97348e-fe0b-40d5-bec3-54dc64ef4ab5
2022
Which of these enzymatic activities limits the speed of lipogenesis?:
The acetyl-CoA carboxylase.
The malonyl transacylase.
The beta-ketoacyl synthase.
Chemistry
The enoyl reductase.
136
2
c8de56a7-fa03-42ad-bb51-92bdb6699450
2022
What is a holoenzyme?
Union of two isoenzymes with identical amino acid structure.
Catalytic entity formed by a cofactor and an apoenzyme.
An ionic prosthetic group.
Chemistry
Union of two organic cofactors.
137
1
1732e462-d99f-4124-a4ab-1fc3f8c7266e
2022
Bilirubin is a breakdown product, mainly of hemoglobin. Some of its characteristics are:
It is transported directly to the liver.
To be highly soluble in water.
It is transported to the liver associated with albumin.
Chemistry
It is transported to the liver associated with biliverdin.
138
4
afe9a29b-44cd-4c44-a20e-3eca26d0d897
2022
The integrins are:
Membrane proteins that act as mediators in cellular adhesion.
Membrane proteins involved in ion transport.
Glucose transport proteins and other monosaccharides.
Chemistry
Extracellular matrix proteins that bind to cell surface proteins.
139
2
2159a658-6daa-40d5-9f8e-c07e91918812
2022
Hormonal stimulation of the formation of the second messenger inositol 1,4,5-triphosphate (IP3) quickly leads to release, of what other intracellular messenger?
Prostaglandin.
Cyclic AMP.
Cyclic GMP.
Chemistry
Calcium.
140
3
9bb7f88f-fafb-49f5-aad8-a32363238ac2
2022
The translation of the nucleotide code of the mRNA into proteins is mediated by the ribosomes in the cytoplasm. Which of the following statements about this process is correct?:
The codons UAG, UGA, and UGC signal the end of a gene.
The ribosome binds to the 3' end of the mRNA to form a chemically stable environment for the rest of the molecules involved in protein synthesis.
The synthesis of proteins begins from the N-terminal end to the C-terminal end.
Chemistry
The amino acid coding sequence is read in groups of three nucleotides in the 3' to 5' direction.
141
4
0dd86e14-e153-4af8-a1b0-f6d16c1b6d42
2022
How does the increase in temperature affect the reaction between antigen and antibody?
Decrease in reaction speed and increase in binding affinity.
Increase in reaction speed and decrease in binding affinity.
Decrease in reaction rate and decrease in binding affinity.
Chemistry
Increase in reaction speed and increase in binding affinity.
142
1
17cccab9-7381-4de6-86b0-79b810afc7b6
2022
Ubiquinone (also called Coenzyme Q) is:
A cytochrome electron transporter in the respiratory chain.
A redox coenzyme with a heme group.
A hydrophobic quinone that transports electrons in the respiratory chain.
Chemistry
A component of the enzyme group that marks proteins for their proteolytic degradation.
143
4
fd65d3f2-d94f-440a-b999-d1853517ee84
2022
Each immunoglobulin molecule contains two light chains and two heavy chains, which can be separated by the loss of one of the following types of interactions:
Disulfide bonds.
Ionic bonds.
Van der Waals Bonds.
Chemistry
Hydrogen bonds.
144
2
4e3bedb8-e26e-43f1-a336-0e7d92b60bff
2022
Which of the following statements about the effects of an insulin increase is false?:
Activates lipogenesis.
Activates gluconeogenesis.
Promotes the uptake of glucose in peripheral tissues.
Chemistry
Activates the synthesis of glycogen.
145
1
e214d611-cf54-4b61-9701-663801ad5845
2022
An International Unit (IU) of enzyme activity is the amount of enzyme that:
Produce 1 mg of product per deciliter.
Converts 1 µmol of substrate into product per liter.
Produces 1 µmol of product per liter.
Chemistry
Converts 1 µmol of substrate into product per minute.
146
3
504616ea-c39d-4c43-bff0-74b91e22857b
2022
Which of the following statements is true only for anabolic pathways?:
They are called cycles if they regenerate an intermediate.
Their irreversible reactions (out of equilibrium) are regulated.
They are divergent and generate a variety of complex compounds.
Chemistry
They converge and generate a few simple products.
147
4
99cdabff-ee05-4596-916c-b669c8e96a8a
2022
Through what mechanism do erythrocytes generate their energy?
Oxidative phosphorylation.
Tricarboxylic acid cycle.
Transfer of electrons to oxygen.
Chemistry
Substrate-level phosphorylation.
148
3
853a2ea4-cf0b-486c-8fbf-43cc144d097d
2022
The factors or regulatory proteins of mRNA transcription in eukaryotes:
They bind to elements or trans sequences.
They bind to elements or cis sequences.
Without them, there is no transcription.
Chemistry
They activate RNA polymerase II.
149
1
edee9177-0e3d-4695-ae85-27c816a7cee7
2022
All of the following sentences correctly describe properties of proteins, except:
The solubility is maximum at the isoelectric point.
Ammonium sulfate typically precipitates proteins while preserving biological activity.
Gel chromatography separates proteins according to their size.
Chemistry
Trichloroacetic acid precipitates and denatures proteins.
150
2
380ff9cb-36c3-420a-a462-c118ab692b99
2022
The high consumption of glucose by cancer cells is due to their greater reliance on anaerobic glycolysis than normal cells. This observation is known as:
Positive cooperative effect.
Warburg Effect.
Latent glycolysis.
Chemistry
Bohr Effect.
151
1
42d9786c-851e-413b-8dcb-6e77cf1f14e6
2022
What is the effect of enzymes on the reactions they catalize?
Increase the speed of the reaction, only in the sense of product formation.
Increase the equilibrium constant of the reaction.
Increase the activation energy of the reaction.
Chemistry
Induce a decrease in the activation energy of the reaction.
152
3
9b4f3d13-7b94-464b-9e7e-dfdcc982edb7
2022
Scurvy is a disease caused by a deficiency in vitamin C. The biochemical effect of this deficiency is:
A lower performance of mitochondrial electron transport, where vitamin C plays an important role.
The absence of retinal synthesis and the consequent loss of vision.
The impossibility of hydroxylation of collagen's proline to hydroxyproline, which leads to serious defects in the structure of this protein.
Chemistry
A defect in an enzyme responsible for the synthesis of fatty acids that leads to severe weight loss.
153
4
983a72c2-c245-4546-b75f-9451c827aa79
2022
In which of the following tissues is the transport of glucose into the cell insulin-dependent?:
Cerebral.
Adipose.
Erythrocytic.
Chemistry
Hepatic.
154
1
e8334a28-5382-430a-9e92-6ce9d6906cee
2022
The proofreading activity of prokaryotic DNA Polymerase I is an activity:
Transesterifier 5- 3'.
5´-3´ Polymerase.
Exonuclease 3' -5'.
Chemistry
5´ -3´ Exonuclease.
155
4
7177016b-44fb-426d-bc62-16977695f335
2022
What will happen if the blood pH goes from being 7.4 to 7.2?
The hemoglobin's affinity for oxygen will decrease.
The binding of oxygen to myoglobin will be affected.
Hemoglobin will not be able to bind 2,3-bisphosphoglycerate in the central space between subunits.
Chemistry
The affinity of hemoglobin for oxygen will increase.
156
2
21c9d918-9a54-4393-ba76-10f2050a94a1
2022
Gluconeogenesis occurs in:
Liver and adrenal cortex and, under fasting conditions, small intestine.
Only liver and adrenal cortex.
Liver and small intestine.
Chemistry
Liver and adrenal cortex and, under fasting conditions, muscle.
157
2
57e0851a-f366-4c92-bfcf-fc830e31f824
2022
All the following amino acids contain only methyl or methylene groups as constituents of their side chains, except:
Alanine.
Leucine.
Lysine.
Chemistry
Isoleucine.
158
4
39b86566-a776-425a-913f-8ba2ad75c6d3
2022
Which of the following statements about the pentose phosphate pathway is not true?:
All the reactions of the pathway occur in the cytoplasm.
It is a closed path, always occurring with the same sequence of reactions.
Some of the enzymes involved are not exclusive to this pathway.
Chemistry
All enzymes involved in this pathway are soluble.
159
1
ab335314-7b61-4163-b60d-029d6cae17b6
2022
Regarding the polymerase chain reaction, indicate the correct answer:
Use an equimolar mixture of ribonucleotide triphosphates (NTPs).
It is a chemical reaction, in vivo, that inhibits the synthesis of eukaryotic nucleic acids.
Does not require primers.
Chemistry
It is done through the action of a thermostable DNA polymerase.
160
3
9ff03340-2c3a-430a-be23-2ede785c30d0
2022
Pyridine reacts with sulfur trioxide to yield:
4-Pyridinium sulfonate.
3-Pyridinium sulfonate.
2-Sulfonate Pyridinium.
Chemistry
1-Pyridinium sulfonate.
161
3
8fb0cbd9-4145-46fb-a890-49997425ed9d
2022
What is the major product obtained after heating 1-ethenyloxy-2-propene?
4-Pentenal.
Propanol.
Pentanol.
Chemistry
Ethyl propyl ether.
162
2
ba9d9077-6fb1-42d3-b235-d465c77144b1
2022
What is it called when an optically active product is formed from an initially optically inactive substance through the use of a chiral catalyst?
Enantiospecific synthesis.
Enantioselective synthesis.
Regioselective synthesis.
Chemistry
Stereospecific synthesis.
163
1
64d77269-8c59-42c1-8f26-686946fa0437
2022
What is the primary organic product obtained in the reaction of hexanoic acid with molecular bromine and traces of phosphorus, followed by treatment with ammonia?
2-Bromohexamide.
Hexanoyl bromide.
2-aminohexanoic acid.
Chemistry
2-Bromohexanoic Acid.
165
4
9620bce8-e016-4dcf-b2de-1bbf681b7b0a
2022
Of the following methods of organic structural determination, which one is not based on the absorption of electromagnetic radiation?
Infrared.
Nuclear Magnetic Resonance.
Ultraviolet-visible.
Chemistry
Mass spectrometry.
166
3
31324fb5-a6ea-4c3d-a368-8347d834a273
2022
Sulfides can be prepared by nucleophilic substitution (SN2) through the reaction of an alkyl halide with a:
Alkanethiolate ion.
Alcoholate ion.
Nitronium ion.
Chemistry
Sulfonium ion.
167
2
fa6c0d3d-a899-4842-b710-6f6b91085962
2022
The acidity order of phenol, cyclohexanol, benzoic acid, and 4-nitrophenol, from least to greatest, is:
Cyclohexanol < 4-Nitrophenol < Phenol < Benzoic acid.
Phenol < Cyclohexanol < 4-Nitrophenol < Benzoic acid.
Cyclohexanol < Phenol < 4-Nitrophenol < Benzoic acid.
Chemistry
Phenol < 4-Nitrophenol < Cyclohexanol < Benzoic acid.
168
4
f8f7079a-3c2f-44cd-ae70-c21db01a99bb
2022
The first stage of the reaction of aldehydes and ketones with primary amines produces:
Imines.
Hemiaminals.
Pyrroles.
Chemistry
Enamines.
169
1
aba3f073-eb49-4c88-985a-4ca0880402a3
2022
What product is obtained when an alkene is treated, first, with Hg(OAc)2 in EtOH, and then, with NaBH4?
An ether.
An epoxide.
An alkane.
Chemistry
A diol.
170
2
c53a9561-ad35-443d-9633-477969747426
2022
Enols are converted into ketones through a process called:
Anomeric effect.
Hybridization.
Protonation.
Chemistry
Tautomerism.
171
3
f0925759-854a-4383-8d2b-02f9d1ecf47f
2022
The only intermolecular attraction forces available between nonpolar molecules like alkanes are:
The dipole-dipole forces.
The electrostatic forces.
Induced dipole-induced dipole forces.
Chemistry
The induced dipole-dipole forces.
172
4
e739c76c-2313-4258-874e-f19026d90c54
2022
Periodic acid causes the breakage of neighboring diols to yield:
A ketone and an alcohol.
Two carbonyls.
Two alcohols.
Chemistry
An aldehyde and an alcohol.
173
1
ad1202aa-813f-4b86-968d-a428ab3ac706
2022
The stereoisomers that are not mirror images are classified as:
Diastereoisomers.
Enantiomers.
Meso forms.
Chemistry
Configurational.
174
2
b5cf1e74-259c-4052-b1f8-b68d5c6da463
2022
In the Merrifield synthesis, the polymeric support to which the peptide chain is attached is:
Polystyrene.
Polyvinyl.
Acrylonitrile.
Chemistry
Polyamide.
176
2
b98f1cc1-5268-4638-aa08-986e2533693c
2022
What is the major organic product obtained in the reaction of ethyl propionate with an excess of propylmagnesium bromide followed by acid workup?
3-Hexanone.
4-Ethyl-4-heptanol.
Propyl propanoate.
Chemistry
Ethyl 2-bromopropanoate.
177
1
718e4c16-1fdf-4606-8db0-6a19763db67c
2022
Which of the following statements, regarding resonance structures, is true?:
The structures with the greatest charge separation are the main contributors to the resonance hybrid.
All resonance structures of a molecule must have the same energy.
All resonance structures have the same contribution to the resonance hybrid.
Chemistry
Only electrons can be delocalized.
178
3
e14e48a5-b21f-4b08-864a-a73bef664a44
2022
What major SN1 product would be obtained by treating 2-bromo-3,3-dimethylbutane with EtOH/H+?
2-ethoxy-2,3-dimethylbutane.
2-ethoxy-3,3-dimethylbutane.
1-ethoxy-2,3-dimethylbutane.
Chemistry
2-ethoxy-2,2-dimethylbutane.
179
2
6699861f-4b3f-4ada-b30c-65632f4fd746
2022
The coupling of an organoboron with an aromatic bromide in the presence of Pd(0), is called:
Stille.
Heck.
Suzuki.
Chemistry
Negishi.
180
4
baefb3c6-dab9-4950-a083-8eeba1145d30
2022
Alkenes react with N-bromosuccinimide to form:
Vinyl Bromides.
Allylic bromides.
Alkynes.
Chemistry
Dibromides.
181
1
54a89054-ff10-47f9-a9e7-bf04f40aa1f9
2022
What product/s would result from treating p-bromotoluene with NaNH2/NH3(liquid):
Equimolecular mixtures of p-aminotoluene and m-aminotoluene.
p-aminotoluene.
Does not react under these conditions.
Chemistry
2-amino-4-bromotoluene.
182
2
3ac5e780-90d8-4b9b-81dc-1ffde8abad47
2022
Which of the following alkyl halides is not suitable for preparing an amine using the Gabriel synthesis?:
1-bromo-3-methylbutane.
2-bromo-3-methylpentane
1-bromo-2,3-dimethylbutane.
Chemistry
2-bromo-2,3-dimethylbutane.
183
3
9329ae52-2000-45fa-a570-38b5afcda361
2022
Which of the following statements is not true?:
The boiling point of chloromethane is higher than that of iodomethane.
In the electrostatic potential maps, the regions rich in electron density appear in red and the ones poor in electron density appear in blue.
The N-bromosuccinimide can be used as a source of bromine in free radical brominations.
Chemistry
The chemistry of vinyl halides is different from that of alkyl halides because their bonding and hybridization are different.
184
2
d983d006-75fc-4867-b5b1-8320d18a42b6
2022
The reaction that transforms pyridine into 2-aminopyridine by treatment with sodium amide in liquid ammonia is known as:
Merrifield Reaction.
Suzuki Reaction.
Chichibabin Reaction.
Chemistry
Oppenauer Reaction.
185
4
1a8cae16-3a7c-4ba2-80ef-bf827d7f115a
2022
The Friedel-Crafts acylation, followed by Clemmensen or Wolff-Kishner reduction, is a standard sequence used for:
Introduce a primary alkyl group into an aromatic ring.
Obtain aromatic ketones.
Obtain benzofurans.
Chemistry
Obtain aromatic aldehydes.
186
2
4dbcbda4-735f-4d41-a7e1-257796b98d3e
2022
Which of the following reagents should be used to prepare, with greater yield, the tBu-O-CH3 via Williamson synthesis?
tBuBr and CH3I.
CH3Br and NatBuO.
tBuOH and NaCH3O.
Chemistry
tBuBr and NaCH3O.
187
1
bd5e2250-a21c-4c27-afa3-cc786c9013c1
2022
When treating 2-pentyne with H2/Lindlar catalyst, what product/s is/are obtained?
Mixtures of cis-2-pentene and trans-2-pentene.
Pentane.
cis-2-pentene.
Chemistry
trans-2-pentene.
188
4
32a9789d-1577-41b6-9ca9-9999551ae3a9
2022
Which of the following statements, referring to the physical properties of alkanes, is false?:
The boiling points of alkanes increase as the molecular mass increases.
For the same number of carbon atoms, a branched alkane has a lower boiling point than its linear isomer.
As they are hydrophobic, alkanes make good lubricants.
Chemistry
For the same number of carbon atoms, a branched alkane melts at a lower temperature than its linear isomer.
189
3
73b7466a-1f0d-488d-ad9e-5149c5fd4234
2022
Ethyl acetate reacts with equimolar amounts of sodium ethoxide to yield:
Ethyl ether.
Ethyl acetoacetate.
Methyl acrylate.
Chemistry
Acetone.
190
1
63f8daea-165a-470b-aea4-ca4baf592068
2022
Indolizidine alkaloids have a nitrogen atom in the fusion of two rings of:
5 and 6 members.
5 and 7 members.
4 and 5 members.
Chemistry
6 and 7 members.
191
2
6d07e529-e209-4dad-8680-e4c09cc9e9c3
2022
The fusion of a benzene ring at positions 2,3 of a pyrrole generates:
An indole.
A quinoline.
An isoquinoline.
Chemistry
A benzofuran.
192
2
42d12267-5f0d-4263-b47c-8acb39ab4df4
2022
In the reaction of a racemic mixture of a product A with an optically pure enantiomer of a product B, the following is formed:
A pair of compounds that are enantiomers.
A pair of compounds that are identical.
A pair of compounds that are constitutional isomers.
Chemistry
A pair of compounds that are diastereomers.
193
3
09ecb676-b83a-4b92-9616-3894a123be7d
2022
What reaction conditions could convert an aniline into a phenol?:
Treatment with sodium hydroxide, followed by heating in water.
Treatment with sodium nitrite in an acidic medium, followed by heating in water.
Treatment with hydrogen chloride, followed by heating in water.
Chemistry
Treatment with thionyl chloride in an acidic medium, followed by heating in water.
194
1
45819663-a582-498c-a5da-8ce2b980e67c
2022
The treatment of 2-methylindole with concentrated nitric/sulfuric acids leads to nitration in the position:
Three.
One.
Five.
Chemistry
Four.
195
4
6f6361d9-1fd4-4936-bf0b-a54382c5c2d6
2022
What is the reason that justifies the fact that the pKa of phenol (9.9) is lower than the pKa of ethanol (15.9)?
The conjugate base of phenol has a localized charge.
The conjugate base of phenol is stabilized by resonance.
The conjugate base of ethanol has a delocalized charge.
Chemistry
The conjugate base of ethanol has a localized charge.
196
1
0c0eacbe-fc3a-4314-93a4-238ead8fcbe5
2022
The structural units responsible for the characteristic reactions of molecules are:
The nuclei.
The atoms.
The rings.
Chemistry
Functional groups.
197
3
b41a75ac-b451-4ef6-81a9-92fcd562faa0
2022
What product/s are obtained by adding Br2/CCl4 to (E)-2-butene?
Meso-2,3-dibromobutane.
2,3-dibromobutane (racemic mixture).
Mixtures of 2,3-dibromobutanes (meso and pair of enantiomers).
Chemistry
(E)-1-bromo-2-butene.
198
2
1e6bc463-1e83-4105-b79e-2d99ff2f3c09
2022
The Clemmensen reduction [Zn(Hg), HCl] allows the transformation of propiophenone (Ph-CO-CH2-CH3) into::
Ph-CHOH-CH2-CH3.
Ph-CH2-CH2-CH3.
Ph-CH=CH- CH3.
Chemistry
Ketones do not react under these conditions.
199
1
8e5575e1-3d92-4e44-916b-4f065b4f192b
2022
Which of the following statements, regarding the reactivity of alkenes, is false?:
The hydroboration-oxidation of 1-methylcyclopentene leads to trans-2-methylcyclopentanol.
The addition of bromine to cyclopentene, in tetrachloromethane, leads to trans-1,2-dibromocyclopentane.
The addition of bromine to cyclopentene, in the presence of water, leads to cis-2-bromocyclopentanol.
Chemistry
The oxymercuration-demercuration (reduction) of 1-methylcyclopentene, using methanol as a solvent, leads to 1-methylmethoxycyclopentane.
200
4
1a876d68-e4b9-45dc-974e-3456be3b747e
2022
Which of the following is a metalloenzyme that contains tungsten?:
Formylmethanofuran dehydrogenase.
Carboxypeptidase A.
Carboxypeptidase B.
Chemistry
Carbon monoxide dehydrogenase.
201
2
5748b0f6-b2b7-4a0b-90e7-acc3dbedd78d
2022
The lightest lipoproteins (density <1.00 g/cm3) are:
High-density ones (HDL).
The low-density ones (LDL).
The very low-density ones (VLDL).
Chemistry
The chylomicrons.
202
3
2ccee6da-a693-4e28-b78c-af34c37d9855
2022
How many nitrogen atoms does an adenine molecule contain?
Four.
Five.
Six.
Chemistry
Three.
203
1
74efd35f-d765-40d9-96c4-a9c9c3952a5a
2022
In a measurement procedure, the smallest concentration of analyte that we are capable of measuring with a previously established accuracy or reliability, is referred to as:
Quantification limit.
Detection limit.
Dilution limit.
Chemistry
Measurement procedure capacity.
205
2
bf52b10f-5959-4f19-80ef-5ab4f8cf4150
2022
What is the composition of the nucleus of deuterium, an isotope of hydrogen?
Two neutrons.
Two protons.
A proton and two neutrons.
Chemistry
A proton and a neutron.
206
3
07d58c8f-7cf4-4fc2-85a6-f0970d3b0707
2022
Rifampicin inhibits transcription in bacteria because:
It binds to the promoter sequences of transcription in the DNA.
It binds to the beta subunit of bacterial RNA polymerases, preventing the eviction of the promoter.
It intercalates into the DNA mold and prevents the elongation of transcription.
Chemistry
Destabilizes the DNA-RNA heteroduplex formed during the elongation process.
207
1
183a9eaa-6dc1-44e9-b4fe-5cadc9e1adf1
2022
A urea solution in water, with a concentration of 0.010 molal, has a freezing point of -0.019ºC. A 0.010 molal NaCl solution will have a freezing point of:
Between 0 and -0.019ºC.
0ºC.
Between -0.019ºC and -0.038ºC.
Chemistry
-0.019ºC.
209
4
d9c7a054-3814-4bb7-8e76-da7997866114
2022
The main source of extracellular cholesterol for human tissues is:
Low-density lipoproteins (LDL).
The very low-density lipoproteins (VLDL).
The chylomicrons.
Chemistry
High-density lipoproteins (HDL).
210
2
5b683aee-1c3b-4ec6-8bf6-b104bba60673
2022
Form A has 24 base pairs per helical turn.
In the B form, the displacement per residue is about 3.4 A.
The structure of form B is shorter and thicker than forms A and Z.
3.
Chemistry
The Z form consists of a right-handed double helix.
1
0
d50092cd-b772-4ca7-a17c-74062af1f76a
2021
Hemolysis significantly affects the serum concentrations of different constituents. Of the following, which is the correct statement?:
The LDH and potassium increase and the sodium decreases.
Potassium increases and sodium and LDH decrease.
The LDH increases and the sodium and potassium levels decrease.
Chemistry
Sodium, LDH, and potassium levels increase.
2
2
134bcbfa-8397-447f-a48e-87a8573929b5
2021
The majority of the reducing equivalents used for the synthesis of fatty acids are generated in:
Glycolysis.
The pentose phosphate pathway.
Gluconeogenesis.
Chemistry
The citric acid cycle.
3
1
4fe58252-cdf4-4aff-b3a1-26520f9fe3b4
2021
If the sequence of a fragment of a DNA chain is 5'- AATGCCTACGGCTTA-3', what will be the sequence of the complementary chain?:
5'- AATGCCTACGGCTTA- 3'
5'- TTACGGATGCCGAAT-3'
5'- UAAGCCGUAGGCAUU-3'.
Chemistry
5'- TAAGCCGTAGGCATT-3'.
4
3
a94ab98d-9b20-4d26-ade9-6d30dd122dfd
2021
Which enzyme does not participate in the pentose phosphate pathway?
Glucose 6-phosphate dehydrogenase.
6-phosphogluconolactonase.
Phosphoglucose isomerase.
Chemistry
6-phosphogluconate dehydrogenase.
5
4
abc95c48-aeb9-476d-a98e-9a4c091fe02d
2021
Regarding Somatostatin, indicate the false answer:
It is a hypothalamic hormone.
It is a tetradecapeptide that inhibits the growth hormone.
It is a hormone that inhibits pancreatic insulin.
Chemistry
It is a hormone that stimulates the secretion of glucagon.
6
3
ee7d75d2-8085-473e-93a2-df442b0d404c
2021
An enzyme that follows a classic Michaelis-Menten kinetics has a Vmax= 100 μM/min and a Km = 15 μM. What will be the reaction rate, V0, when [S] = 10 μM?
50 μM/min.
40 μM/min.
100 μM/min.
Chemistry
70 µM/min.
7
1
286f23a0-b992-4713-8cf8-2e09b139ac63
2021
Which of the following statements is correct for the citric acid cycle?:
Several molecules of oxygen are used directly in the oxidation of acetyl-CoA.
It produces several ATP molecules in each turn.
The main control point of the cycle is the initial reaction of the same, inhibited by ADP.
Chemistry
Its intermediates can be replenished by anaplerotic reactions.
8
3
ce325749-7b6c-4df4-8534-1ad6b7c780eb
2021
The term proteome refers to:
The post-translational modifications that proteins undergo.
The set of all protein-coding genes of an organism.
The set of proteins produced by the genome of a cell.
Chemistry
The set of proteins present in the lysosomes.
9
4
3e724cba-92a8-4acc-a835-1145fd6fd84f
2021
Trans fatty acids:
They promote an increase in the concentration of high-density lipoproteins (HDL)
They constitute the natural form of unsaturated fatty acids in animal tissues.
They are predominantly generated in partial hydrogenation industrial processes.
Chemistry
They have a melting temperature lower than their cis configuration equivalents with the same number of C atoms and unsaturations.
10
4
90a0cae3-93a6-4464-905b-4ceb0dc4d86c
2021
Which of the following options related to the bond of oxygen with hemoglobin is false?:
The Bohr effect causes a higher affinity of hemoglobin for oxygen at acidic pH values.
Carbon dioxide reduces the affinity of hemoglobin for oxygen and shifts the dissociation curve to the right.
The affinity of hemoglobin for oxygen increases as the saturation percentage does.
Chemistry
The 2,3-bisphosphoglycerate decreases the affinity of hemoglobin for oxygen.
11
2
f518684d-5261-476b-a2bc-d4a1a095c076
2021
Which of the following functional domains is not present in the structure of nuclear receptors?:
DNA binding domain.
Transmembrane domain.
Regulation domain of transcription.
Chemistry
Ligand binding domain.
12
1
712c09be-ab9e-4b2e-b108-b3ee3a5a8fb2
2021
One of the following sentences describes the effect produced by the acidification of the blood plasma on haemoglobin:
The response of hemoglobin to the variation of partial pressure of O2 ceases to be sigmoidal.
Hemoglobin increases its affinity for O2.
The partial pressure of O2 at which hemoglobin is half-saturated (P50) increases.
Chemistry
Hemoglobin loses part of its iron (Fe2+) content.
13
4
9bb2aee6-9732-4ab8-a0c3-31dc51d45fe1
2021
Which of the following steps in cholesterol biosynthesis is the rate limiting and the site of metabolic regulation?:
Geranyl pyrophosphate → Farnesyl pyrophosphate.
3-Hydroxy-3-methylglutaryl CoA → Mevalonic acid.
Squalene → Lanosterol.
Chemistry
Lanosterol → Cholesterol.
14
1
34d9f24e-b570-40c8-b844-93a809310965
2021
The aquaporins:
They form hydrophilic transmembrane channels for the passage of solutes dissolved in water.
They form hydrophilic transmembrane channels for the passage of water.
They form hydrophilic transmembrane channels for the passage of sugars.
Chemistry
They form hydrophilic transmembrane channels for the passage of monovalent ions.
16
1
c272207b-46e1-4919-b52f-6968eadfb70e
2021
What is it that is actually measured to determine the absorbance of a chromogen?
The decrease in the intensity of the light that reaches the detector.
The energy of the light that reaches the detector.
The relationship between the intensity of light, reaching the detector, of the chromogen and the blank.
Chemistry
The increase in the intensity of the light that reaches the detector.
17
4
c39a16c5-3455-4549-9d14-645d79561abf
2021
Which of the following statements regarding a double-helix DNA molecule is true?:
The bases are perpendicular to the axis.
All hydroxyl groups of pentoses participate in the bonds.
Each chain replicates itself.
Chemistry
Each chain is parallel.
18
2
d7be44e2-6ae9-4a59-ab42-dcda4994dbfd
2021
Which of the following statements is correct for the electron transport chain?:
All complexes in the transport chain pump protons into the intermembrane space.
Electrons flow from positive reduction potentials to negative reduction potentials.
Complex IV transfers electrons from cytochrome c to oxygen.
Chemistry
Ubiquitin and cytochrome c are mobile elements that each transport a pair of electrons.
19
4
2ec8d154-be57-4a6c-ac11-54a214e25eeb
2021
How can a prozone effect be detected in an immunoturbidimetric method?
Measuring the absorbance after the concentration of the sample.
Measuring absorbance after ultrafiltration.
Measuring the absorbance after treating the sample with sodium dodecyl sulfate (SDS).
Chemistry
Measuring the absorbance after dilifying the sample.
20
3
16872ded-a316-4fbb-9bda-d0f3fb2fd1b5
2021
The greatest buffering capacity at physiological pH would be provided by a protein with an abundance of which of the following amino acids:
Histidine.
Lysine.
Leucine.
Chemistry
Aspartic Acid.
21
2
1c62693d-8cf2-40f8-93c3-0559de3ec5bf
2021
Which of the following statements is not true about the secondary structure of DNA?:
There is always the same number of purines as there are pyrimidines.
It is always with a right turn.
The denaturation of the double strand causes an increase in absorbance at 260nm.
Chemistry
The most common conformation is in the form of BDNA.
22
1
1ecbe2dd-9692-48af-ba50-f422bd3f3124
2021
Which of the following statements about the reverse transcriptase enzyme is correct?:
It is encoded in the genome of all viruses.
It has RNA polymerase activity.
It uses RNA as a template and retrotranscribes it to DNA.
Chemistry
It does not possess DNA polymerase activity.
23
4
9a9875c5-55db-4403-9fc5-e49305d44a48
2021
Which of the following terms is used to describe the movement of solutes in conventional electrophoresis:
Size or mass.
Electrophoretic mobility.
Composition of amino acids.
Chemistry
Isoelectric point.
24
1
adbd4743-0b5c-4778-a3b4-05550619e946
2021
Genomic libraries or gene banks:
They provide catalogs of all protein-coding genes cloned by insertion into a cloning vector.
They provide catalogs of all the genes in an organism's genome cloned by insertion into a cloning vector.
They are collections of cataloged prokaryotic genes.
Chemistry
They are collections of genes that code for RNAs cloned by insertion into a cloning vector.
25
1
b7d6f9a3-b8fd-4130-9fc0-d4a524f08def
2021
Which trace element plays an important role as a cofactor of carbonic anhydrase?
Manganese.
Selenium.
Copper.
Chemistry
Zinc.
26
3
a99611cf-4b14-4b25-a0fb-43dbe6208aea
2021
Which of the following statements is correct for ATP synthase?:
The F0 subunit has half-channels that allow protons to return from the intermembrane space to the matrix.
The F1 subunit, oriented towards the intermembrane space, is capable of hydrolyzing ATP.
The F0 subunit synthesizes ATP thanks to conformational changes.
Chemistry
The F1 subunit channels the passage of protons from the intermembrane space to the matrix and synthesizes ATP.
27
2
d15f7db1-9dad-4163-adbd-cfd1bb7027ff
2021
The recombinant DNA:
It is hybrid DNA obtained through homologous recombination.
It is obtained through the formation of heteroduplexes by hybridization of DNA fragments from different origins.
It is obtained using restriction endonucleases and DNA ligase.
Chemistry
It is supercoiled cellular hybrid DNA.
28
4
8fe8a07f-68de-48b3-9509-a8519343d55f
2021