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http://holisticmindtherapy.org/index.php/home/blog/142-can-pain-ever-be-a-good-thing | 2019-11-14T21:43:55 | s3://commoncrawl/crawl-data/CC-MAIN-2019-47/segments/1573496668539.45/warc/CC-MAIN-20191114205415-20191114233415-00287.warc.gz | 0.96139 | 621 | CC-MAIN-2019-47 | webtext-fineweb__CC-MAIN-2019-47__0__8834095 | en | Can Pain Ever Be A Good Thing?
Believe it or not, pain can definitely be a good thing. In fact, I would go so far as to say that pain is absolutely essential. Without pain to warn us that something is wrong, we would continue to expose ourselves to danger. We might remain blissfully unaware of serious injury – a serious burn, broken bone, or deep cut.
A perforated ulcer or burst appendix could kill us, simply because we would lack the sensations that tell us that something is hurting us very badly. Psychological pain is no different. Our mental anguish is often revealed through various symptoms such as depression, anxiety, or irritability.
Past trauma can result in extreme psychological dysfunction – negatively affecting a person in a number of different ways, and on many different levels.
The main difference here, though, is that we are often wrongly encouraged to ignore our psychological pain by minimizing it, or even pretending that it doesn’t exist. No one would advocate continuing to walk on a broken leg, and yet it is all too common to push on through incredible feelings of hurt and sorrow as if everything is more or less okay.
Just like physical pain, psychological pain is there for a reason. It is trying to tell us that something is wrong and that we need to pay close attention. In fact, if we continue to ignore our psychological pain, we often find that our body works even harder to get us to listen! For example, a low mood can lead to a chronic headache. If we continue to disregard our important emotions, we may find ourselves with a lowered immune system – falling ill with every sore throat and runny nose that comes our way.
Holistic mind therapy is a natural healing practice that focuses on the whole body. In particular, it offers the opportunity to connect with our powerful subconscious mind – identifying our true feelings, and recognizing areas that need to change. Personal transformation can take place when an individual is able to understand the reasons behind their own harmful behavior.
Emotional turmoil is an important clue that something is out of balance and needs to be fixed. A person may not even be aware of why they continue to sabotage themselves with destructive habits. An angry emotional outburst may provide the only clue that there is something in a person’s life that needs to be resolved. Hypnosis can address all this and much more, by opening the subconscious mind to accept positive suggestion.
Troublesome events from the past can be reframed, enabling the person to finally move forward with his or her life, again. This is why I say pain is a good thing. Without it, we might be tempted to keep going, even when we need to stop, and take care of ourselves. Part of good mental health involves setting aside some time to replenish our spirits and restore our mental and physical energy.
By noticing when we are feeling out of sorts, we are able to take action, rather than carrying on until something really bad happens. Pain in this case, is our very own personal messenger. | medical |
https://www.edgetechnicalsolutions.com/product/resguardo-o2-kit/ | 2022-01-26T13:29:51 | s3://commoncrawl/crawl-data/CC-MAIN-2022-05/segments/1642320304954.18/warc/CC-MAIN-20220126131707-20220126161707-00309.warc.gz | 0.894877 | 407 | CC-MAIN-2022-05 | webtext-fineweb__CC-MAIN-2022-05__0__149068667 | en | Resguardo O2 Kit
Resguardo O2 Kit
O2 Kits are versatile and designed to provide your staff and/or patients with protection in the case of any medical Emergencies, from fainting to cardiac arrest. They provide a supplementary oxygen supply while also reducing pain and Discomfort.
Accidents can happen and in many cases, time can be the difference between life and death. Any medical emergency, even minor ones, can cause hypoxia or insufficient oxygen supply to the tissues which can cause Pain, discomfort and possibly even death. Therefore, it is important to have effective medical aids in place, while waiting for the Ambulance to arrive.
The ability to administer supplemental oxygen is imperative during medical emergencies such as breathlessness, sudden Cardiac or pulmonary arrest. However, mouth to mouth resuscitation only delivers 16% of oxygen while 6 LPM oxygen Administered resuscitation only delivers 50%. In acute medical emergencies, this is unlikely to be enough. That is why our O2 Kits utilize a 12 LPM oxygen flow so that 100 percent oxygen is delivered to the patient ensuring a quick recovery and thereby Preventing fatalities.
- Portable and lightweight.
- The oxygen kit can be used continuously for 50 minutes. (Under 6LPM sitting).
- CPR resuscitator adjunct for a non-breathing victim.
- Can be wall mounted
- Face mask with resuscitation provision.
- Easy to operate using simple on-off mechanism.
- Life of the cylinder is 15 years.
- No additionally training needed to use the product
- Ease of storage
- Cylinder – Aluminum (BS EN 1SO : 7866 : 2012)
- Capacity – 2.2 LTR, 300 LTRS of oxygen
- Settings – Normal and High
- Normal – LPM – 50 minutes
- High – 12 LPM – 25 minutes
- Cylinder life – 15 Years | medical |
https://www.phri.org/genfx-review/ | 2021-01-16T21:35:54 | s3://commoncrawl/crawl-data/CC-MAIN-2021-04/segments/1610703507045.10/warc/CC-MAIN-20210116195918-20210116225918-00777.warc.gz | 0.953246 | 2,032 | CC-MAIN-2021-04 | webtext-fineweb__CC-MAIN-2021-04__0__208682464 | en | In this GenFX review, you will see why this is one of the best all-natural HGH supplements in the market. It is going to help you to counter the negative changes that occur in your body with age.
Change is inevitable. However, when it is your body changing, you can control how fast the changes occur. You see, these are negative changes where your skin, organs, cells, bodily functions and others start to degenerate.
Because age is such a big deal, there are millions of products in the market that claim to reverse aging. Most of these are fake products masquerading as the real deal. In addition, no product can reverse aging. However, if you choose a good one, it can slow down aging. It can also help you to reverse the effects of aging.
Among some of the top companies that have emerged first in the race to slow down the aging process is Leading Edge Health.
Backed by science going as back as the early 1950s, it has been proven that the decline of HGH levels in the body causes accelerated aging.
Therefore, Leading Edge Health bases its formulations on this premise. Consequently, their products such as HyperGH 14X, Provacyl, GenF20 Plus, and now GenFX help you to age gracefully.
Overview: What Is GenFX?
This HGH releaser supplement is in the form of pills. However, it does not contain the human growth hormone itself. What it does is to enhance the process by which the body produces HGH.
Research shows that HGH secretion in the body declines by up to 10% every decade. Therefore, there is a need to replenish the body’s ability to secrete this hormone. This is where GenFX HGH pills come in.
But just why do you need high HGH levels in the body? First, it is going to increase your metabolic rate. Therefore, your body can burn fat faster.
In addition, this leads to the release of more energy. Therefore, if you work out, you can have the energy and the strength to work out longer and harder.
HGH also enhances the health of your skin. Because it helps in cell regeneration and development, you can get a more elastic and flawless skin.
Other benefits of high HGH levels include better sex life, immune boosting, high quality sleep and many others.
Overall, it is to your best interest to restore your HGH levels. You can do that by using GenFX HGH supplement. It comes in the form of 60 pills in one box. Since it is a formulation of natural ingredients only, there are no side effects to worry about.
The GenFX ingredients are mainly amino acids and plant extracts. They are blended in world-standard labs using the best extracts so that their nutrients remain intact. Here is a sneak peek into some of the ingredients:
You will find this amino acid in all natural anti-aging products. In GenFX, it is included because of its prowess to release HGH and increase circulation. In addition, it also works hand-in-hand with the other amino acids to stimulate the pituitary gland to release more HGH.
Mainly, the L-Lysine amino acid helps the L-arginine to do its work in a better way. In addition, research has shown that people who were injected with L-Lysine recorded an increased level of HGH in their blood.
This amino acid helps to boost the immunity. In addition, it enhances faster cell regeneration. Therefore, it can help improve the skin. At the same time, it can help in the rejuvenation of your internal organs and improve bodily functions.
Products that contain glutamine help to improve brain health. For instance, they can help increase alertness and concentration.
This one mainly helps in muscle repair and recovery. Therefore, if you work out hard, the tissues must tear up so that as they heal, they can increase in volume. Methionine will help your muscles heal faster so that you can work out again and increase your muscle mass.
L-Valine is going to increase metabolism in the muscles. This powers them up so that you can work out longer and harder. The main benefit of high metabolism is that it releases more energy.
When you have engaged in extreme workout, you need this ingredient because it will help you recover faster. In addition, research shows that Panax Ginseng has a direct impact on the release of HGH.
This amino acid has the ability to help sharpen your cognitive ability. In addition, it enhances alertness, memory and concentration. You must agree that these faculties suffer most when you age.
This is going to improve the way you sleep. One of the side effects of aging is that sleep keeps reducing. In effect, it affects many of the bodily functions. Therefore, you need gelatin because it will help you sleep longer and better.
Anterior Pituitary Extract
This ingredient is processed from the pituitary gland of other animals. It has the ability to stimulate your Pituitary gland to secrete more HGH.
There are more ingredients. As you can see here, GenFX HGH pills are a combination of many ingredients. Each of these helps the body in a different way.
However, collectively, they make this formula that enhances the production of HGH in the body. In addition, L-Arginine helps to improve the circulation. Therefore, when more HGH, testosterone and other hormones are released, they are transported easily to different parts in the body.
How GenFX Works
This HGH supplement works in a very simple way. By this, we mean that within a few to several weeks of taking this supplement, you should start feeling its positive effects in different areas of your health.
For instance, you should start feeling strong and energetic where you were feeling weak and fatigued. In addition, you should see some improvement in your sexual desire and performance. Basically, here is how GenFX works:
Stimulates your Pituitary Gland to produce more HGH
The natural ingredients in this supplement are going to stimulate the pituitary gland. That way, it can start secreting more HGH. Of course, the mechanics behind this entire process are complex. However, the brain is stimulated to send signals to the pituitary gland of the need for more HGH in the system. Therefore, it increases its secretion of the same.
It increases testosterone levels
While this is not mainly a testosterone booster, it still helps a lot in that regard. On the same note, remember that testosterone also contributes to the growth of the muscles, giving you more energy and enhancing your performance in bed. Therefore, its functions are almost the same as those of the HGH hormone. When the HGH levels in your system rise, the testosterone level also increases.
Boosts immunity and metabolic rate
You can enjoy a huge boost in the metabolic rate and immunity. This has many benefits. For instance, high metabolism means that the cells produce more energy. Therefore, you can exercise harder and longer. This can be very helpful if you want to lose weight.
You have seen that some of the amino acids in the GenFX HGH pills help to increase metabolic rate within the cells. Since fat is a reserve of the excess calories that you consume, when your metabolic rate is high, there is faster metabolism of fat cells. Therefore, with a good workout regimen, you can start rebuilding the same lean muscle mass that you had in your youth.
You will also enjoy a huge immune boost to ward off illnesses. One of the ways that this HGH supplement does that is by enhancing sleep. When you sleep longer and sounder, you can enjoy cell regeneration, immunity boost, skin rejuvenation and other boons.
How To Use GenFX HGH Pills
The manufacturer says that you need to take 2 pills a day. You can take them with water for faster absorption into your bloodstream.
Therefore, since one box comes with 60 pills, that is a supply for one month. However, to see the best results, you should at least use it consistently for 60 days. Therefore, we recommend that you order at least 2 boxes.
On the same note, do not throw away the boxes because you are covered by a money back guarantee of 67 days. You can return the opened and unopened boxes for a refund if you feel that the HGH pills are not helping you, within 67 days of purchasing.
|Enhances your sexual desire and performance||Best that you buy it online on official website|
|You can sleep better and longer||You have to use it for at least 60 days consistently for results|
|Simple to use|
|No side effects because it has natural ingredients|
|More energy to work out longer|
|Helps you burn fat and build lean muscle|
Where to Buy GenFX
We recommend that you order GenFX HGH pills from the official website only. There, you are going to enjoy various benefits. For instance, the more boxes that you buy, the more discounts you will enjoy.
When you order a 6-month supply, you can save close to $20 over what you would pay for 1-month supply. You can even order a whole year’s supply. Every purchase is covered by a 67-day money back guarantee.
To conclude, most people never find the need to return the GenFX HGH supplement because it works. However, we recommend that you take it for at least 60 days.
After that, you can have a small break and continue taking it again. You see, maintaining the recommended HGH level is a lifestyle rather than a one-off thing.
Do not overdose. In addition, read the user instructions in the provided manual before you can take this supplement. | medical |
http://assenddragonaviation.com/index.php/aviation-articles/antidepressants-and-special-issuance | 2019-04-19T10:40:23 | s3://commoncrawl/crawl-data/CC-MAIN-2019-18/segments/1555578527566.44/warc/CC-MAIN-20190419101239-20190419123239-00284.warc.gz | 0.901208 | 1,552 | CC-MAIN-2019-18 | webtext-fineweb__CC-MAIN-2019-18__0__96026584 | en | SSRI ANTIDEPRESSANTS AND THE SPECIAL ISSUANCE
PROCESS UNDER THE HIMS/IMS PROGRAM
RB “Doc” Hecker
FAA HIMS/IMS Senior AME 20969
1943 Aeronca O-58B / L-3B USAAF 43-26975 NC47185 Based at 1T8 Bulverde, TX
The FAA is currently limiting consideration of Special Issuance Medical Certificates to only four (4) medications used as single therapy agents; not used in combination. These four medications are:
Fluoxetine (Prozac), Sertraline (Zoloft), Citalopram (Celexa), and Escitalopram (Lexapro).
As these medications are becoming increasingly accepted by the FAA and are commonly used within the medical community, these four antidepressants have been safely prescribed in appropriate aeromedical cases with proper oversight by specifically trained AMEs who act as Independent Medical Sponsors (IMS). These medications have fewer side effects than previously used generations of antidepressants. While the focus of the current policy statement is on individuals being treated for depression, the FAA realizes that these four medications may be used to treat conditions other than depression. It should be noted, therefore, that in all instances, the FAA will continue to consider pilot applicants and make determinations on a case-by-case basis under the special-issuance process just as it always has. In addition to treating psychiatrists, AMEs who have specialized training under a program called the Human Intervention and Motivation Study (HIMS) also will assist the FAA by making recommendations about certification cases to be considered under this present policy. The HIMS program is a safety-critical aviation program that was established nearly 40 years ago. The original program, developed specifically for commercial pilots, was designed as an alcohol and drug assistance program to coordinate the identification, assessment, treatment, and medical certification of pilots in need of help with their addiction or dependence problems.
Under HIMS, pilots who successfully meet rigorous FAA protocols for alcohol abuse, drug abuse, depression and other mental health disorders requiring single dose medication, may be returned to duty in accordance with 14 CFR § 67.401. The FAA will apply the basic HIMS evaluation and monitoring approach to this new policy and HIMS/IMS AMEs will participate in a specialized training program tailored to evaluating and monitoring applicants who wish to be considered for Special Issuance under this policy.
CONSIDERATION FOR PILOT APPLICANTS WHO DESIRE SPECIAL ISSUANCE OF A MEDICAL CERTIFICATE WITH REGARD TO DEPRESSION TREATED WITH SINGLE AGENT MEDICATION
This protocol applies to considerations for Special Issuance medical certification for airmen requesting First, Second, or Third Class special issuance medical certificates, for the exercise of privilege under
14 CFR Parts § 121, § 135, or § 91, who are being treated with certain approved antidepressant medications.
CRITERIA TO BE CONSIDERED WITH APPLICATION FOR A SPECIAL ISSUANCE UNDER HIMS PROGRAM
Mild to moderate depressive disorders, such as:
1. Major Depressive Disorder (mild to moderate) either single episode or recurrent episode
2. Dysthymic Disorder
3. Adjustment disorder with depressed mood
Pharmacologic Agents Considered (single-agent use only):
1. Fluoxetine (Prozac)
2. Sertraline (Zoloft)
3. Citalopram (Celexa)
4. Escitalopram (Lexapro)
Specifically Unacceptable Diagnoses and or Symptoms:
2. Suicidal ideation (thoughts)
3. History of electro convulsive therapy (ECT)
4. Treatment with multiple concurrent antidepressant medications
5. History of multi-agent drug protocol use (prior use of other psychiatric drugs in conjunction with antidepressant medications)
1. All symptoms of the psychiatric condition for which treatment is indicated must be ameliorated by the single medication and the condition must be stable with no change in or exacerbation of symptoms for 12 months prior to certification
2. Airman must be on a stable dosage of medication for a minimum of 12 months prior to certification
3. Airman must have no aeromedical significant side effects of prescribed medication.
Required Reports and Consultations for Initial Consideration:
1. A consultation status report (and follow-up reports as required) from a treating psychiatrist attesting to and describing the applicant's diagnosis, length and course of treatment, dosage of the antidepressant medication taken, and presence of any side effects from the antidepressant the applicant takes or has taken in the past
2. A written statement prepared by the applicant describing his or her history of antidepressant usage and mental health status
3. A report of the results of neurocognitive psychological tests with provision of the raw test data: This includes, but is not limited to: COGSCREEN AE, Trails A/B; Stroop Test; CCPT, PASSAT, Wisconsin Card Sorting Test
4. An evaluation and a written report from a HIMS-trained AME who has reviewed items 1, 2, and 3 above, and who makes a recommendation for a Special Issuance Medical Certificate
5. Any additional information the Federal Air Surgeon may require to make a determination under the provisions of this program
December 20, 2014
RB “Doc” Hecker (SRA 5171) is a FAA Senior HIMS/IMS AME (20969) who retired from the US Army Medical Department in 1997 after 26 years of service. He holds certificates for CFI Single Engine Land & Sea, Commercial Pilot ASEL, ASES, AMEL, AMES, Glider, B-17 SIC and Instrument Airplane along with an A&P Mechanic Certificate. He has logged over 2,500 hours and prefers small, intimate airparks. He has restored a 1965 Cessna C210E (N4904U), a 1946 Taylorcraft BC12-D (NC43306),a 1946 Aeronca 7AC (NC2241E), refurbished a 1943 Aeronca O-58B / L-3B (NC47185), 1945 Stinson L-5CVW Sentinel (N178) and a 1947 Taylorcraft BC12-D (N43928). He is currently refurbishing a, and assisting the restoration of a 1947 Aeronca 7BCM / L-16 (N119TX). His other projects include maintaining a 1942 Boeing A75-N1. He has previously owned a Cessna C-172 (N61785), a Grumman AA-5B (N74447) and a Mooney M20C (N10AD). In his free time, Doc practices medicine in San Antonio, TX. He is a member of EAA Chapter 35 of San Antonio, TX, EAA Chapter 92 of Orange, CA, and is an EAA Technical Counselor and Flight Advisor. In addition, he is a Life Member of the Commemorative Air Force and affiliates with the Houston Wing (Houston, TX), Centex Wing (San Marcos, TX), and is an active member of the Gulf Coast Wing (Houston, TX) where he crews as a Co-Pilot, Flight Engineer and member of the maintenance team doing sheet metal and fabric repair work on that magnificent 1945 B17-G war bird “Texas Raiders” (N7227C). | medical |
https://www.velo.com/ch/en/velo-thr | 2023-12-01T04:01:58 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679100264.9/warc/CC-MAIN-20231201021234-20231201051234-00838.warc.gz | 0.893901 | 721 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__121830773 | en | 99% LESS TOXICANTS*? WHAT DOES IT MEAN?
VELO nicotine pouches contain 99% less toxicants than conventional cigarette smoke*. This comparison is based on an assessment of smoke from a scientific standard reference cigarette (approximately 9mg tar) and components released during use of a VELO pouch, in terms of the average of the 9 harmful components the World Health Organization recommends to reduce in cigarette smoke.
Pair that 99% less toxicants* with a large range of flavor options and ease of use, and we’ve all got something to be happy about.
IS THIS NEW FOR VELO?
No, it’s the same VELO nicotine pouches that adult nicotine consumers have had since the brand’s launch. Recently we concluded scientific studies to prove that VELO nicotine pouches contain 99% less toxicants than conventional cigarette smoke*. But we’re sharing the magic number with you now, because we have the science to prove it. And hey, it’s always nice to share something worth celebrating.
OK, BUT HOW IS VELO DIFFERENT THAN CIGARETTES?
VELO nicotine pouches are a modern take on nicotine. Unlike cigarettes, you don’t need a lighter or anything else to enjoy nicotine as VELO nicotine pouches do not involve combustion. Now you can enjoy the next generation of nicotine with no smoke, no ash and no tar**. The pouch is also completely tobacco-free and colorless – meaning it won’t stain your teeth. We don’t know about you, but that gives us something more to smile about.
ARE POUCHES SAFER?
Even though VELO contains less toxicants than cigarettes, it’s still a nicotine product. Although 100% tobacco-free, the pouches contain nicotine – which is an addictive substance and the pouch should not be ingested.
VELO is recommended for adult smokers and current adult nicotine users. It is not suitable for people under 18 years old. Those who are pregnant, breastfeeding, or allergic to nicotine should refrain from using VELO. If you have an unstable heart condition, hypertension, or diabetes, you should avoid nicotine and tobacco products. Please seek out medical advice and stop using VELO if you experience irregular heartbeat, allergic reactions (rashes, itching or swelling of the tongue, mouth or throat), nausea, headache, feeling faint or any other unusual effect.
TOBACCO-FREE NICOTINE POUCHES: WHAT’S IN THEM?
VELO pouches contain pure nicotine, water, and other food-grade ingredients, including plant-based materials, flavoring, and sweeteners. Food grade means these ingredients are high-quality and safe for consumption.
With all this newfound knowledge, you can enjoy your VELO nicotine pouches in a variety of flavors and nicotine levels. What are you waiting for? Go discover your new favorite pouch flavor today!
*This product is not risk-free and contains nicotine, an addictive substance. Comparison based on an assessment of cigarette smoke (ie.; a scientific standard reference cigarette of approximately 9mg tar) and components released during use of a Velo pouch, with reference to the World Health Organisation’s recommendation to reduce the quantities of 9 harmful components in cigarette smoke.
** This product is not risk-free and contains nicotine, an addictive substance. | medical |
https://vonkbv.com/en/politie/ | 2024-02-27T06:41:53 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947474671.63/warc/CC-MAIN-20240227053544-20240227083544-00171.warc.gz | 0.924043 | 320 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__134600574 | en | The medical plastic cases are IP67 waterproof and dustproof. The suitcases have an interior that has been specially developed to transport your medical supplies in a well-organized manner. Medical supplies include bandages, AEDs and medical instruments, all of which must be hygienically packaged and transported.
This series of cases is widely used by government agencies, ambulances, defense and industrial companies.
VONK Medical cases
Vonk B.V. has also developed various medical suitcase interiors. These can be found, among other things, in the many ambulances in the Netherlands. Go to the cases.
Vonk B.V. also has thermal packaging from Peli BioThermal™ in its range.
Peli BioThermal™ offers various thermal packaging options for temperature-sensitive products. Products that react violently to temperature changes must be protected. Go to the range.
This page is still under construction.
Peli™ 1460EMS – Protector™ case is an indestructible medical case with a built-in interior specially formulated for medical use.
The suitcase was designed in collaboration with the emergency medical services.
The case also comes with Peli™’s Unlimited manufacturer’s warranty.
More information about this suitcase can be found under the information button below.
Monday: 09:00 to 17:00
Tuesday: 09:00 to 17:00
Wednesday: 09:00 to 17:00
Thursday: 09:00 to 17:00
Friday: 09:00 to 17:00 | medical |
https://www.enablemart.com/reel-3-receptive-expressive-emergent-language-test-3rd-edition | 2020-02-19T20:24:22 | s3://commoncrawl/crawl-data/CC-MAIN-2020-10/segments/1581875144167.31/warc/CC-MAIN-20200219184416-20200219214416-00482.warc.gz | 0.916002 | 327 | CC-MAIN-2020-10 | webtext-fineweb__CC-MAIN-2020-10__0__22475991 | en | Ages: birth through 3 years
Testing time: 20 minutes
Typically used to screen for emergent language-learning problems, support clinical diagnosis, set intervention goals, and measure delays in infants with congenital anomalies and physical handicaps. Test results are helpful in determining the effect of physical and/or environmental risks on early speech and language development.
Consists of two core subtests - Receptive Language and Expressive Language - and a supplementary subtest - Inventory of Vocabulary Words. Results are obtained from a caregiver interview.
Based on a contemporary linguistic model and includes current studies relating to normative base, reliability, and validity. Normative sample includes 1,112 infants and toddlers from around the nation. Demographic characteristics of the sample were matched to those of the United States according to the 2000 census. The average reliability coefficients for all the test scores are high (exceeding .90) Test/retest studies show that the REEL-3 is stable over time.
The REEL-3 can be used for the following purposes:
Screening infants and toddlers for emergent language-learning problems
Screening older preschoolers in whom delays are expected
Obtaining a description of a child's present language environment
Aiding clinical diagnosis
Setting intervention goals
Measuring delays in emergent speech and language development in infants with congenital anomalies and medically related handicaps
Complete kit includes Examiner's Manual and 25 Profile/Examiner Record Booklets.
We deliver an unparalleled customer experience so you can support the health of your students to enable them to learn and perform to the best of their abilities. | medical |
http://imitrex.ksen.info/ | 2018-01-18T05:22:13 | s3://commoncrawl/crawl-data/CC-MAIN-2018-05/segments/1516084887067.27/warc/CC-MAIN-20180118051833-20180118071833-00141.warc.gz | 0.901055 | 4,414 | CC-MAIN-2018-05 | webtext-fineweb__CC-MAIN-2018-05__0__254057828 | en | When did your headaches first start? Such reactions can be life threatening or fatal. It is possible that some side effects of sumatriptan may not have been reported. Pedialyte, to replenish my electrolytes and minerals. Pregnancy Category C: There are no adequate and well-controlled trials in pregnant women. In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality. When administered by the intravenous route to pregnant rabbits, sumatriptan was embryolethal. Imitrex Tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. uhit.info cardura
Do you have any chest pain, heart disease, shortness of breath, or irregular heartbeats? Respiratory: Bronchospasm in patients with and without a history of asthma. You've got lots of options to ease the pain. First, your doctor will need to know how often you get headaches and how bad they are. That will help her decide on a treatment plan for you.
Cavazos JE, Caress JB, Chilukuri VR, Devlin T, Gray L, Hurwitz BJ "Sumatriptan-induced stroke in sagittal sinus thrombosis. Heart Rate: Transient increases in blood pressure observed in some patients in clinical studies carried out during sumatriptan's development as a treatment for migraine were not accompanied by any clinically significant changes in heart rate. The maximum single recommended adult dose of IMITREX Injection is 6 mg injected subcutaneously. Controlled clinical trials have failed to show that clear benefit is associated with the administration of a second 6-mg dose in patients who have failed to respond to a first injection.
What are the ingredients in Imitrex Tablets? Safety and efficacy have not been established in patients younger than 18 years. Do you have risk factors for heart disease such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are postmenopausal or a male over 40? They are especially helpful if you have moderate to severe that interfere with your ability to perform daily tasks. IMITREX and AMERGE are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products. naproxen
She prescribed Compazine Prochlorperazine. Refill Cartridge Packs are available. This medication may interfere with certain laboratory tests including bleeding times, adrenal function tests possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. The use of Imitrex Tablets is contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Imitrex Tablets. Some of these reactions occurred in patients without known CAD. AMERGE, IMITREX, IMITREX STATdose System, and IMITREX STATdose Pen are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products.
This Patient Information leaflet summarizes the most important information about Imitrex. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about Imitrex that is written for healthcare professionals. If your symptoms do not improve or if they become worse, check with your doctor. Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody diarrhea; burning or aching in your feet or toes; burning, numbness, or tingling; constipation; diarrhea; fainting; feeling or heaviness or tightness in your leg muscles; fever; hearing problems; leg cramps; seizures; severe or persistent headache, dizziness, nausea, or vomiting; severe stomach pain; very cold or blue fingers or toes; vision changes or loss of vision; weight loss; wheezing. Read the Guide provided by your before you start using this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist. These side effects can increase the risk of falling. epoetin-alfa
Consult your doctor before -feeding. Put the Cartridge Pack in the Carrying Case. Therefore, do not use this medication more often or for longer than prescribed. Throw away the seal. Open the lid over the Syringe Cartridge. After a better Tuesday, the diarrhea returned on Wednesday. Are you trying to become pregnant? F. Protect from light. They work great if you have about four headaches per month, but for people with more you need a triptan. Imitrex is great for about two headaches per week, but anymore than that and you risk being like me. I am resistant to about everything. Stick to a routine. Complete common tasks in the same order each time you do them. Pen see Figure B inset. Medicines to stop headaches aren't working well for you. Before injecting IMITREX, check with your doctor on acceptable injection sites and see the instructions inside the carton on discarding empty syringes and reloading an autoinjector device. diphenhydramine brand india diphenhydramine
General information about the safe and effective use of Imitrex. But doctors have found that inhaling pure oxygen can work very well to bring relief. Pain medicine such as that goes inside the nose helps some people. Choose and Prepare the Injection Site. Renal Impairment: The effect of renal impairment on the pharmacokinetics of sumatriptan has not been examined. Use Imitrex spray as directed by your doctor. Check the label on the medicine for exact dosing instructions. Use calendars and clocks. Visser WH, Jaspers NMWH, Devriend RHM, Ferrari MD "Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patients. By educating doctors to look for signs of skin sensitivity in migraine patients, they can instruct patients to take the drugs early and may be able to improve the effectiveness of these drugs. Call your doctor for medical advice about side effects. Other Events Observed in the Clinical Development of IMITREX: The following adverse events occurred in clinical trials with IMITREX Tablets and IMITREX Nasal Spray. Because the reports include events observed in open and uncontrolled studies, the role of IMITREX in their causation cannot be reliably determined. All reported events are included except those already listed, those too general to be informative, and those not reasonably associated with the use of the drug. It's so bad that most people can't sit still and will often pace during an attack. The clinical significance of this binding is unknown. Nov. 7, 2003 -- The success or failure of treatment with the most commonly prescribed may depend on timing. zyban online singapore
My doctor tells me my body couldn't handle the return to normal food, and reacted with the diarrhea and subsequent headaches. The dosage is based on your medical condition, age, and response to treatment. If there is no improvement in your symptoms, do not take more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your comes back, you may take another dose at least two hours after the first dose. Do not take more than 2 doses in a 24-hour period. Seizures have been reported following administration of Imitrex. Some have occurred in patients with either a history of seizures or concurrent conditions predisposing to seizures. There are also reports in patients where no such predisposing factors are apparent. Imitrex Tablets should be used with caution in patients with a history of epilepsy or conditions associated with a lowered seizure threshold. Radiolabeled 14C-sumatriptan administered orally is largely renally excreted about 60% with about 40% found in the feces. Most of the radiolabeled compound excreted in the urine is the major metabolite, indole acetic acid IAA which is inactive, or the IAA glucuronide. Only 3% of the dose can be recovered as unchanged sumatriptan. IMITREX STATdose Pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case NDC 0173-0739-00. Read the Patient Information Leaflet if available from your pharmacist before you start taking sumatriptan and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Overuse of Imitrex spray can cause your headache to become worse. Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor. Sumatriptan belongs to a group of drugs called triptans. It affects a certain natural chemical serotonin that constricts blood vessels in the brain. It may also block other pain pathways in the brain. The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. If you feel unwell in any other way or have any symptoms that you do not understand, you should contact your doctor immediately. Ear, Nose, and Throat: Deafness. You may begin to sweat a lot, or light may bother you. Medicines can help you feel better. But they can also be dangerous, especially if you don't take them the right way. Be safe with medicines. Read and follow all instructions on the label.
Eye: Infrequent was irritation of the eye. How should I take Imitrex? IMITREX. Such reactions can be life threatening or fatal. These drugs are similar to the in this medication and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose to prevent or usually at dosages of 81-325 milligrams a day you should continue taking the aspirin unless your doctor instructs you otherwise. IMITREX Injection is indicated for 1 the acute treatment of migraine attacks with or without aura and 2 the acute treatment of cluster headache episodes. Then close the lid. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Sumatriptan may also be used for purposes not listed in this medication guide. What is the most important information I should know about Imitrex Statdose sumatriptan injection? buy cyclophosphamide email
What should I tell my healthcare provider before taking IMITREX? But these medicines may not be as effective as other medicines, such as triptans. In patients who experience symptoms or signs suggestive of non-coronary vasospasm reaction following the use of any 5-HT 1 agonist, rule out a vasospastic reaction before receiving additional Imitrex Injections. Take one sumatriptan tablet whole with a full glass of water. Do not split the tablet. Do not discard the auto-injector. You may use it again with refills of the prefilled syringes. However, if you are using a one-time use auto-injector, discard the auto-injector after use. If you are unsure if your auto-injector can be re-used, ask your pharmacist. Keep all medicines away from children and pets. Some sumatriptan side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Corneal Opacities: Sumatriptan causes corneal opacities and defects in the corneal epithelium in dogs; this raises the possibility that these changes may occur in humans. chloroquine money order payment usa chloroquine
To prevent upset, take this medication with food, milk, or an antacid. Do not break, crush, or chew the tablet. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Use: For the acute treatment of cluster headache. What other drugs will affect sumatriptan? Increase in Blood Pressure: Significant elevation in blood pressure, including hypertensive crisis, has been reported on rare occasions in patients with and without a history of hypertension. Sumatriptan is contraindicated in patients with uncontrolled hypertension see . Sumatriptan should be administered with caution to patients with controlled hypertension as transient increases in blood pressure and peripheral vascular resistance have been observed in a small proportion of patients. Syringe Cartridge to the Cartridge Pack. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Cerner Multum, Inc. "Australian Product Information. It is not known if IMITREX is safe and effective in children under 18 years of age. Pen from accidentally firing until you are ready. Parenteral drug products should be inspected visually for particulate matter and discoloration before administration whenever solution and container permit. The treatment of migraine headaches with or without aura eg, flashing lights, wavy lines, dark spots. It may also be used for other conditions as determined by your doctor. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets. Dogs receiving oral sumatriptan developed corneal opacities and defects in the corneal epithelium. baclofen
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Shortness of breath; wheeziness; heart throbbing; swelling of eyelids, face, or lips; or a skin rash, skin lumps, or hives happens rarely. If it happens to you, then tell your doctor immediately. You should not use sumatriptan if you have any history of heart disease or coronary artery disease, blood circulation problems, Wolff-Parkinson-White syndrome, uncontrolled high blood pressure, severe liver disease, circulation problems affecting your intestines, history of a stroke, or if your headache seems to be different from your usual migraine headaches. Have you had, or do you have, epilepsy or seizures? kroger generic minocin
Frequency not reported: Accommodation disorders, blindness, conjunctivitis, diplopia. Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw commonly occur after treatment with Imitrex Tablets and are usually non-cardiac in origin. However, perform a cardiac evaluation if these patients are at high cardiac risk. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. plavix purchase online store europe
Sit down. Gently blow your nose to clear the nasal passages. Keep your head in an upright position, gently close 1 nostril with your index finger, and breathe out gently through the mouth. With your other hand, hold the container with your thumb at the bottom and your index and middle finger on either side of the nozzle. Insert the nozzle into your open nostril about ½ inch. Do not press the blue plunger yet. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. cost risperidone comp
Table 2 below, onset of relief began as early as 10 minutes following a 6-mg IMITREX Injection. Smaller doses of sumatriptan may also prove effective, although the proportion of patients obtaining adequate relief is decreased and the latency to that relief is greater. Cerena, a small device for people who have an aura before a migraine. You hold it at the back of your head at the first sign of a headache, and it gives off a magnetic pulse that stimulates part of the brain. Techniques to stop negative thoughts. | medical |
https://www.midwesthealthfoundation.org/incontinence.html | 2022-10-06T07:58:09 | s3://commoncrawl/crawl-data/CC-MAIN-2022-40/segments/1664030337731.82/warc/CC-MAIN-20221006061224-20221006091224-00152.warc.gz | 0.946462 | 1,171 | CC-MAIN-2022-40 | webtext-fineweb__CC-MAIN-2022-40__0__94688515 | en | Fecal incontinence can have several causes:
Fecal incontinence is most often caused by injury to one or both of the ring-like muscles at the end of the rectum called the anal internal and/or external sphincters. The sphincters keep stool inside. When damaged, the muscles aren't strong enough to do their job, and stool can leak out. In women, the damage often happens when giving birth. The risk of injury is greatest if the doctor uses forceps to help deliver the baby or does an episiotomy, which is a cut in the vaginal area to prevent it from tearing during birth. Hemorrhoid surgery can damage the sphincters as well.
Fecal incontinence can also be caused by damage to the nerves that control the anal sphincters or to the nerves that sense stool in the rectum. If the nerves that control the sphincters are injured, the muscle doesn't work properly and incontinence can occur. If the sensory nerves are damaged, they don't sense that stool is in the rectum. You then won't feel the need to use the bathroom until stool has leaked out. Nerve damage can be caused by childbirth, a long-term habit of straining to pass stool, stroke, and diseases that affect the nerves, such as diabetes and multiple sclerosis.
Loss of Sphincter tone
The anal sphincter stays contracted to maintain the integrity of the rectum and prevent soiling and relaxes with a bowel movement. Over time and with age, the sphincter tone can diminish, causing loss of control.
Loss of Storage Capacity
Normally, the rectum stretches to hold stool until you can get to a bathroom. But rectal surgery, radiation treatment, and inflammatory bowel disease can cause scarring that makes the walls of the rectum stiff and less elastic. The rectum then can't stretch as much and can't hold stool, resulting in fecal incontinence. Inflammatory bowel disease also can make rectal walls very irritated and thereby unable to contain stool.
Diarrhea, or loose stool, is more difficult to control than solid stool that is formed. Even people who don't have fecal incontinence can have an accident when they have diarrhea.
Pelvic Floor Dysfunction
Abnormalities of the pelvic floor can lead to fecal incontinence. Examples of some abnormalities are decreased perception of rectal sensation, decreased anal canal pressures, decreased squeeze pressure of the anal canal, impaired anal sensation, a dropping down of the rectum (rectal prolapse), protrusion of the rectum through the vagina (rectocele), and/or generalized weakness and sagging of the pelvic floor. Often the cause of pelvic floor dysfunction is childbirth, and incontinence doesn't show up until the mid-40s or later.
The doctor will ask health-related questions and do a physical exam and possibly other medical tests.
Treatment depends on the cause and severity of fecal incontinence; it may include dietary changes, medication, bowel training, or surgery. More than one treatment may be necessary for successful control since continence is a complicated chain of events.
Food affects the consistency of stool and how quickly it passes through the digestive system. One way to help control fecal incontinence in some persons is to eat foods that add bulk to stool, making it less watery and easier to control. Also, avoid foods that contribute to the problem. They include foods and drinks containing caffeine, like coffee, tea, and chocolate, which relax the internal anal sphincter muscle. Another approach is to eat foods low in fiber to decrease the work of the anal sphincters. Fruit can act as a natural laxative and should be eaten sparingly.
You can adjust what and how you eat to help manage fecal incontinence.
What to Do About Anal Discomfort
The skin around the anus is delicate and sensitive. Constipation and diarrhea or contact between skin and stool can cause pain or itching. Here's what you can do to relieve discomfort:
Because fecal incontinence can cause distress in the form of embarrassment, fear, and loneliness, taking steps to deal with it is important. Treatment can help improve your life and help you feel better about yourself. If you haven't been to a gasteroenterologist yet, make an appointment.
Everyday practical Tips
Fecal incontinence is the inability to control your bowels. Symptoms of fecal incontinence can be the inability to make it to a toilet after feeling the urge to have a bowel movement, or the unexpected leakage of stool from the rectum.
More than 6.5 million Americans have fecal incontinence. It affects people of all ages--children as well as adults. Fecal incontinence is more common in women than in men and more common in older adults than in younger ones.
It is not, however, a normal part of aging.
Loss of bowel control can be devastating. People who have fecal incontinence may feel ashamed, embarrassed, or humiliated. Some don't want to leave the house out of fear they might have an accident in public. Most try to hide the problem as long as possible, so they withdraw from friends and family. The social isolation is unfortunate, but there are treatment options that can help to reduce social anxiety, improve bowel control, and make incontinence easier to manage. | medical |
http://www.huntspine.com/about/meet-dr-gabriel-hunt/ | 2017-02-19T11:44:49 | s3://commoncrawl/crawl-data/CC-MAIN-2017-09/segments/1487501169769.33/warc/CC-MAIN-20170219104609-00234-ip-10-171-10-108.ec2.internal.warc.gz | 0.950703 | 428 | CC-MAIN-2017-09 | webtext-fineweb__CC-MAIN-2017-09__0__214732285 | en | Meet Dr. Gabriel Hunt
Gabriel E. Hunt, Jr., MD is a neurosurgeon who focuses on the treatment of spinal cord injuries and spinal trauma, the treatment of complex spinal disorders, as well as tumors and vascular abnormalities of the skull base, spine, and spinal cord.
Known by his patients and peers as one of the most skilled spine doctors Los Angeles has available, Dr. Hunt believes in utilizing a minimally invasive approach to treat all appropriate spinal disorders. In addition to his private practice with Hunt Spine, he is an attending neurosurgeon at the Cedars-Sinai Department of Neurosurgery and the Cedars-Sinai Spine Center.
Primary areas of research interest for Dr. Hunt include new advances in the treatment of spinal cord injuries and developing new minimally invasive surgical technologies. As a knowledgeable and influential Los Angeles spine doctor, he is a member of the American Medical Association, American Association of Neurological Surgeons, and the Congress of Neurological Surgeons.
Dr. Hunt has written articles for several peer-reviewed publications, including Neurosurgical Focus, American Journal of Obstetrics and Gynecology and Neurological Research. He has given numerous presentations in his areas of expertise in the United States and abroad. He was also a recipient of a Howard Hughes Research Fellowship while attending the University of California, Los Angeles (UCLA) School of Medicine.
Dr. Hunt began his higher education with a bachelor’s degree from the University of California, Los Angeles (UCLA) and his medical degree from the UCLA School of Medicine. He completed an internship in general surgery and a residency in neurological surgery at Thomas Jefferson University Hospital and the Jefferson Hospital for Neuroscience in Philadelphia. Dr. Hunt received specialized training in the treatment of complex spinal disorders, spinal trauma, and spinal cord injuries through participation in the Orthopedic and Neurosurgical fellowship program at the Delaware Valley Regional Spinal Cord injury Center at Thomas Jefferson University.
If you're looking for a skilled spine doctor in Los Angeles, schedule a consultation today to discuss your spinal condition with Dr. Gabriel Hunt. | medical |
http://atozarticles.info/ | 2017-07-26T02:36:12 | s3://commoncrawl/crawl-data/CC-MAIN-2017-30/segments/1500549425751.38/warc/CC-MAIN-20170726022311-20170726042311-00463.warc.gz | 0.978667 | 337 | CC-MAIN-2017-30 | webtext-fineweb__CC-MAIN-2017-30__0__147678298 | en | The latest craze about a weight loss supplement is the extract of Garcinia Cambogia, which is a fruit that grows mainly in tropical Indonesia. The results of researchers obtained till now points to the fact that the extract can prevent the production of fat in the body, and reduce hunger. It has led to many people being attracted to the supplement in ever increasing number. For a huge number of people, the extract has worked wonders.
What are people saying?
In some case, a person who had been taking 3000 mg per day in the form of 2 capsules in the morning, afternoon and evening before breakfast, lunch and dinner respectively for two months continuously has lost almost 25 lbs. Yet another person has posted a review saying that Cambogia Garcinia for weight loss has been responsible for keeping the amount of food taken daily to a low level. It helped with daily workouts for the weight loss program as it reduced the tendency to have snacks between meals.
Are all people satisfied?
Not all people are satisfied with the effect of the extract. One of the reviews posted says that the person had started taking the pill before having any food every day for a month. Food with low carbohydrate was consumed along with a one-hour physical exercise workout performed daily. At the end of the month, the person had lost zero lbs. and is convinced that weight loss does not happen with the help of a pill. The physical structure of each individual is different from the other, and it is the reason the extract of Garcinia Cambogia has different kinds of effect on different people. The only option is to try it and find out for yourself whether it works for you or not. | medical |
https://ghlifetv.com/mtn-ghana-increases-1-call-data-charges-effective-1-may/ | 2021-10-18T05:20:13 | s3://commoncrawl/crawl-data/CC-MAIN-2021-43/segments/1634323585196.73/warc/CC-MAIN-20211018031901-20211018061901-00163.warc.gz | 0.926757 | 288 | CC-MAIN-2021-43 | webtext-fineweb__CC-MAIN-2021-43__0__156280309 | en | Telecommunication giant, MTN Ghana, has served notice it will increase its call and data charges effective 1 May 2021.
It said in a text message to its subscribers that “following the introduction of the COVID-19 Health Recovery Levy, resulting in a 1% increase in the National Health Insurance Levy, your talk time/ data volumes will be adjusted to reflect the tax change.”
“This takes effect from 1 May 2021. Keep safe and remember to wear your mask everywhere you go. Thank you,” MTN Ghana added.
About the COVID-19 levy
During the presentation of the 2021 Budget, the government introduced COVID-19 Health Levy of 1% on VAT, Flat Rate Scheme and a 1% on National Health Insurance Levy (NHIL) as part of revenue measures to help the economy recover.
According to the government, the levies will be used for the procurement of vaccines and establishment of 14 medical waste treatment facilities.
It will also “assist in the construction of 33 major health projects, the recruitment of more health professionals and Agenda 111.”
Agenda 111 would see the construction of 100-bed capacity district hospitals in 101 districts with no hospitals. It is the latest ever investment in healthcare infrastructure in Ghana’s history and a massive vision by the Akufo-Addo-led administration for Ghana’s healthcare sector. | medical |
http://ucdental.net/template.jsp?doc=ucdental&c=Home&wiz=0&page=Home | 2021-12-09T07:20:50 | s3://commoncrawl/crawl-data/CC-MAIN-2021-49/segments/1637964363689.56/warc/CC-MAIN-20211209061259-20211209091259-00249.warc.gz | 0.942523 | 195 | CC-MAIN-2021-49 | webtext-fineweb__CC-MAIN-2021-49__0__148708177 | en | Dr. Harpole is a native of West Tennessee and has practiced for over 32 years. Our staff provides routine dental care including cleanings , full-mouth reconstruction ,crowns, bridges, partials, dentures, implants, cosmetic fillings , root canals, oral surgery (wisdom teeth removal /surgical extractions) and emergency dental services for the entire family . Anesthesia services are routine for oral surgical procedures . Additionally, patients request IV anesthesia for other dental services we provide, making their visit most comfortable . We take great pride in providing superior dental care and our goal is to make your visit as relaxing and informative as possible while delivering the quality of care patients are seeking in a non-rushed environment. Dr. Harpole's focus is for the "dental anxious" and has provided IV anesthesia for over 26 years of his 32 years in practice.
EMERGENCY AND NEW PATIENTS WELCOME | medical |
https://matters.midsussex.gov.uk/issue-24-may-2022/wellbeing/prediabetes-talks | 2023-12-10T13:04:46 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679102469.83/warc/CC-MAIN-20231210123756-20231210153756-00460.warc.gz | 0.942632 | 283 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__310264466 | en | Our Wellbeing team is hosting free pre-diabetes talks to help local people who are at risk of developing type 2 diabetes.
The number of people being diagnosed with type 2 diabetes is increasing nationally and developing the condition means an increased risk of developing serious complications such as blindness, heart attack, stroke and amputation. Thankfully it's possible to reduce the risk of developing type 2 diabetes by making some key lifestyle changes like eating well, being active and maintaining a healthy weight.
Those most at risk of developing type 2 diabetes people with a family history of the condition, a Body Mass Index (BMI) over 25 and those who have been identified by a health professional as pre-diabetic.
The pre-diabetes workshops show people how they can take control for themselves and reduce the risk of developing the condition. The course looks at small and manageable steps that individuals can take to avoid developing type 2 diabetes, such as changes to diet, activity levels and other lifestyle factors.
The pre-diabetes workshops take place at
East Grinstead Library
13 May, 2pm-4pm
Cherry Tree Centre, Burgess Hill
24 May, 10am-12pm
7 June, 10am-12pm
If you are interested in booking a free place please contact the Mid Sussex Wellbeing Team on 01444 477191 or email [email protected] | medical |
https://wholesomeliving.ca/live-blood-microscopy | 2023-11-28T09:15:08 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679099281.67/warc/CC-MAIN-20231128083443-20231128113443-00705.warc.gz | 0.935406 | 532 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__188236305 | en | If you could view your health from the inside, what would you do differently?
Live blood microscopy is an educational and nutritional assessment tool which may reveal key information about the internal terrain of the body that either protects us or leaves us open to the development of degenerative conditions.
This is done by taking a drop of blood from your finger and viewed under a dark field microscope at over 1000x magnification. As this is being done, you will be able to see it on a screen while I explain and answer any questions. The analysis allows us to look at the root causes that may lead to issues and symptoms (e.g. fungal, pathogens, lack of antioxidants, digestive disturbances, toxicities etc.).
This can reveal over 50 aspects of health such as:
This assessment is NOT a tool used to diagnose or treat disease. As mentioned, this is performed for educational and nutritional purposes only.
What to expect
1. Go to the page APPOINTMENT to schedule a time to meet.
2. The forms will be sent to you once you schedule an appointment (from practice better), so please check your email.
3. Fast for at least 3 hours before your appointment and drink 3 glasses of water. You may use the bathroom as needed.
4. Prior to doing the assessment we will address concerns and get to know what your goals, get to know you and go through your intake form.
5. During the assessment, a lancet is used to obtain one drop of blood and it is placed on two slides to do a Live Blood Analysis as well as a Dry Blood Analysis.
6. During this time, we will look at the slides together on a screen and provide recommendations to improve your nutritional status.
7. If needed, nutritional consultations can also be scheduled, and a plan of action will be discussed.
8. In order to track your progress a follow up appointment is scheduled if required.
Your bloodstream transports oxygen and other essential agents to maintain the health within your body. It is a means for detoxification by bringing waste to the liver and kidneys to be eliminated. As a result it is able to indicate imbalances before symptoms appear.
A Darkfield Microscope is used to look at a live blood sample and observe conditions that are not visible through regular testing methods. Using the Darkfield Microscope at various magnifications allows a practitioner to view the shape and function of blood cells, platelets, metabolic by products and pathogens eg. micro-organisms. Distorted red blood cells can show nutritional deficiencies, oxidative damage or fungal and bacterial forms throughout the sample. | medical |
https://lms.flightwingsaviation.com/groups/oxolvan-ambroxol-clenbuterol-para-que-sirve-oem-ambroxol-clenbuterol/ | 2024-04-14T18:11:42 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296816893.19/warc/CC-MAIN-20240414161724-20240414191724-00427.warc.gz | 0.852261 | 4,211 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__126605559 | en | Oxolvan ambroxol clenbuterol para que sirve. Oxolvan with ambroxol and clenbuterol: Their uses and benefits
Do you suffer from frequent respiratory disorders such as bronchitis or asthma? If yes, then Oxolvan Ambroxol Clenbuterol is the perfect solution for you!
Oxolvan Ambroxol Clenbuterol is a combination drug that effectively treats respiratory disorders by alleviating symptoms such as cough, wheezing, and shortness of breath. Ambroxol is a mucolytic agent that helps break down mucus in the lungs, making it easier to cough up. Meanwhile, Clenbuterol is a bronchodilator that opens up the airways, making breathing easier.
When used in the right dosage, Oxolvan Ambroxol Clenbuterol is safe and effective. However, it’s important to consult a doctor and follow the prescribed dosage to avoid any side effects. Some common side effects include headache, nausea, and dizziness, but they usually go away within a few days.
Don’t let respiratory disorders hinder your daily activities. Try Oxolvan Ambroxol Clenbuterol for immediate relief. Order yours today and breathe easy!
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If you are experiencing respiratory distress, you know how it can limit your life and negatively impact your health. You need a solution that works effectively and quickly to help you live your life to the fullest. Introducing OEM Ambroxol Clenbuterol: the ultimate solution for your respiratory needs.
Developed by leading experts in the industry, OEM Ambroxol Clenbuterol is a powerful combination of Ambroxol and Clenbuterol – two highly effective ingredients that work together to provide relief from respiratory problems. Ambroxol helps to break down mucus and clear your airways while Clenbuterol helps to open up your airways, making it easier to breathe.
Whether you are suffering from asthma, bronchitis, or any other respiratory condition, OEM Ambroxol Clenbuterol can help you breathe easier and feel better. It is a safe and effective solution that you can trust to give you the relief you need.
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Oxolvan Ambroxol Clenbuterol also has beneficial effects on your immune system. It stimulates the production of white blood cells and antibodies, which are necessary for fighting off infections and diseases. It can also reduce the severity and duration of colds, flu, and other respiratory infections.
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Oxolvan Ambroxol Clenbuterol is a safe and effective medication that is widely used around the world. It has been extensively tested and proven to provide quick relief for respiratory conditions and enhance fitness performance. It is available in various formats, including tablets, syrups, and inhalers, and can be prescribed by a healthcare professional.
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If you are ready to experience the amazing benefits of Oxolvan Ambroxol Clenbuterol, order yours today. You can easily purchase it online or visit your local pharmacy and get it prescribed by your doctor. Say goodbye to respiratory problems, achieve your fitness goals, and boost your immune system with Oxolvan Ambroxol Clenbuterol.
Is OEM Ambroxol Clenbuterol safe for pregnant or breastfeeding women?
OEM Ambroxol Clenbuterol should not be used during pregnancy or breastfeeding unless directed by your healthcare provider. It is important to discuss the potential risks and benefits of this medication with your healthcare provider before taking it.
What are the possible side effects of Oxolvan Ambroxol Clenbuterol?
Side effects of Oxolvan Ambroxol Clenbuterol may include nausea, headache, dizziness, tremors, and palpitations. It’s important to talk to a healthcare professional if any of these side effects are severe or persistent.
What are the possible side effects of OEM Ambroxol Clenbuterol?
The side effects of OEM Ambroxol Clenbuterol may include headache, tremors, palpitations, sweating, nausea, and vomiting. In rare cases, more serious side effects may occur, such as chest pain, difficulty breathing, or allergic reactions. Contact your healthcare provider if you experience any concerning symptoms.
What is OEM Ambroxol Clenbuterol used for?
OEM Ambroxol Clenbuterol is a medication used to treat respiratory diseases such as asthma, bronchitis, and pneumonia. It works by relaxing and widening the airways in the lungs, making it easier to breathe.
Is Oxolvan Ambroxol Clenbuterol safe to use during pregnancy?
It’s important to consult with a healthcare professional before using any medication during pregnancy. The safety of Oxolvan Ambroxol Clenbuterol during pregnancy has not been fully studied, so it is not recommended for use without medical advice.
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If you’re considering taking Oxolvan Ambroxol Clenbuterol, it’s important to follow the recommended dosage guidelines to ensure safe and effective use of the medication. The dosage recommendations may vary depending on the specific condition being treated and other factors such as age, weight, and overall health.
For adults and children over 12 years old, the recommended dosage of Oxolvan Ambroxol Clenbuterol is typically 1-2 tablets or capsules per day, taken with food. It’s best to space out the doses evenly throughout the day to maintain consistent levels of the medication in the body.
If you’re taking this medication for a specific condition such as bronchitis or asthma, your doctor may adjust the dosage or recommend a different dosing schedule based on your symptoms and response to treatment.
It’s important to not exceed the recommended dosage of Oxolvan Ambroxol Clenbuterol, as this can increase the risk of side effects and adverse reactions. If you miss a dose, take it as soon as possible, but do not take a double dose to compensate for a missed one.
Always consult with your doctor before starting or adjusting your dosage of Oxolvan Ambroxol Clenbuterol, and be sure to inform them of any other medications or supplements you’re taking to avoid potential drug interactions.
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While the combination of oxolvan ambroxol and clenbuterol is widely used for treating respiratory disorders, it comes with a fair share of side effects. The drug has been reported to cause several adverse reactions ranging from mild to severe.
Anxiety: The drug can cause excessive nervousness, restless behavior, and an overwhelming sense of fear or worry.
Nausea: It may lead to nausea and vomiting, especially if taken on an empty stomach.
Cardiovascular problems: The drug can increase the heart rate, leading to palpitations, irregular heartbeats, and other cardiac complications.
Jitters: It can cause tremors or shaking of hands, legs, or other body parts involuntarily.
Hypokalemia: Prolonged use of the drug can lead to potassium deficiency, which can cause muscle weakness, fatigue, and abnormal heart rhythms.
If you experience any of these side effects, seek medical attention immediately. Do not delay or ignore any symptoms, as they can worsen over time and lead to serious health complications.
To avoid any adverse reactions, it is crucial to use the drug only as prescribed by your healthcare provider and maintain a healthy lifestyle. Avoid smoking, alcohol consumption, and stress that can aggravate respiratory issues and increase the risk of adverse reactions.
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Ambroxol is an international product. It is a mucolytic agent used in the treatment of acute and chronic respiratory tract disorders associated with viscid mucus. Clenbuterol is a beta 2 agonist used by sufferers of breathing disorders as a decongestant and bronchodilator. There are no evaluations for ambroxol-clenbuterol. Ambroxol + Clembuterol [+ Clenbuterol] Ramos, Nicaragua; Ambroxol 0. 3% TIS Farmaceutic, Romania; Ambroxol 0. In the active-controlled studies included in this review, it is suggested that the efficacy of ambroxol is, at a minimum, non-inferior to that of NAC, SCMC and sobrerol. 10 January 2023 A large-scale Phase 3 clinical trial to establish ambroxol’s potential to slow the progression of Parkinson’s disease, is being led by UCL researchers, and will start in early 2023. Ambroxol is a drug which is currently used to treat respiratory conditions. Marca AMBROXOL CLEMBUTEROL CALOX Sustancias AMBROXOL, CLENBUTEROL Forma Farmacéutica y Formulación Jarabe Presentación Frasco con vaso dosificador, 120 ml, 15 – 0,01/5 mg/ml Agregar a interacciones medicamentosas COMPOSICIÓN INDICACIONES TERAPÉUTICAS PROPIEDADES CONTRAINDICACIONES PRECAUCIONES. O clenbuterol foi patenteado em 1967 e entrou em uso médico em 1977. Propriedades do Ambroxol + Clenbuterol Indicações Afecções das vias respiratórias agudas e crónicas que decorram com broncospasmo e alteração da formação e transporte das secreções, em especial:. Ambroxol works to thin down and break up phlegm (sputum) and is used to clear congestion in the treatment of respiratory diseases which have thick phlegm or too much phlegm. Ambroxol is also used as a pain reliever for sore throats as it has a local numbing effect. Ambroxol starts working about 30 minutes after it has been taken. Ambroxol and Clenbuterol Tablets (60 mg ambroxol and 40 mg clenbuterol) in the morn-ing with 250 ml warm water. Then the same standard lunch was provided 4 h after adminis – tration. The blood collection from ulnar vein was performed before administration and at 0. 5, 3, 4, 6, 8, 12, 24, 36, 48, 72, 96 and 120 h post administration. Ambroxol is an international product. It is a mucolytic agent used in the treatment of acute and chronic respiratory tract disorders associated with viscid mucus. Clenbuterol is a beta 2 agonist used by sufferers of breathing disorders as a decongestant and bronchodilator. There are no evaluations for ambroxol-clenbuterol
Oxolvan ambroxol clenbuterol para que sirve
FARMACOCINÉTICA Y FARMACODINAMIA: El clorhidrato de ambroxol se absorbe completamente después de haber sido administrado por vía oral (por biodisponibilidad de 60% aproximadamente, pues 1/3 de la dosis es metabolizada como efecto de primer paso en el hígado). Forma farmacéutica y formulación: Solución: cada 100 ml contiene: clorhidrato de ambroxol 150,0 mg; clorhidrato de clenbuterol 100,0 mcg. Solución (gotas pediátricas): cada 100 ml contiene: clorhidrato de ambroxol 750,0 mg; clorhidrato de clenbuterol 500,0 mcg. Estimular la producción de una sustancia llamada surfactante, que crea una película que recubre los pulmones, impide que se acumule moco y facilita que se produzca la oxigenación. Hacer que los cilios funcionen más activamente. Disminuir la inflamación bronquial. Clenbuterol para el asma. Ambroxol es un medicamento usado para las afecciones de las vías respiratorias tanto agudas como crónicas. Es conocido como un mucolítico-expectorante y recibe este nombre porque disminuye la consistencia viscosa de las secreciones bronquiales, lo que ayuda a su expulsión. La vida media es de 9-10 horas. Con administración repetida de la dosis terapéutica no se ha revelado indicio alguno de acumulación. El ambroxol se fija en 90% a las proteínas plasmáticas. Se transforma en diversos productos metabólicos inactivos que se eliminan en su mayor parte como conjugados hidrosolubles, por ejemplo, glucurónidos
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I had a persistent cough for almost a week and decided to try Oxolvan Ambroxol Clenbuterol based on a friend’s recommendation. I was a little hesitant at first because I haven’t heard of the brand before, but I was pleasantly surprised. The medicine worked really quickly and I felt relief within the first day of taking it. The dosage was easy to follow too. I didn’t experience any side effects, but I made sure to read the label carefully and follow the instructions. Overall, I’m really happy with this product and would recommend it to others.
I’ve been dealing with a cold for over a week now and my cough has been really persistent and annoying. I decided to try Oxolvan Ambroxol Clenbuterol after doing some research online and seeing all the positive reviews. I was a little skeptical at first because I’ve never heard of the brand before, but I figured it was worth a shot. The package arrived quickly and the instructions were easy to follow. I took the medicine as directed for a few days and I was really impressed with the results. My cough started to improve within the first day and by the third day, it was completely gone. I couldn’t believe how fast it worked! I didn’t experience any side effects either, which was a relief. I’ve had bad experiences with other cough medicines in the past, so I was really hesitant to try something new. But I’m so glad I did! The combination of ambroxol and clenbuterol really seemed to work well for me. Overall, I would definitely recommend Oxolvan Ambroxol Clenbuterol to anyone who is dealing with a cough. It’s effective, easy to use, and doesn’t have any unpleasant side effects. I’m really happy with my purchase and would definitely buy it again if I needed to.
I used Oxolvan Ambroxol Clenbuterol for my cough and it worked really well. I only needed to take it for a few days and felt much better afterwards. I didn’t experience any side effects either.
Similar articles: infinity-charmed.nl/medistar-clenbuterol-review-hidrocloruro-de-clenbuterol/, sounds-healing.com/2023/07/23/5-weeks-on-clenbuterol-clenbuterol-stacked-with-ephedrine/, T3 yohimbine and clenbuterol | medical |
https://www.lifeandatrophy.com/filmmaker | 2019-05-27T07:53:46 | s3://commoncrawl/crawl-data/CC-MAIN-2019-22/segments/1558232262029.97/warc/CC-MAIN-20190527065651-20190527091651-00033.warc.gz | 0.984182 | 336 | CC-MAIN-2019-22 | webtext-fineweb__CC-MAIN-2019-22__0__61037512 | en | As the son of two geneticists, science has always been a part of my family. I never entirely knew the nature of my father's research, except that he worked on a disease called Spinal Muscular Atrophy (SMA). This disease is a rare, genetic, neuromuscular disease which causes progressive muscle weakness. It affects 1 in every 10,000 births and is the number one cause of genetic death in infants. While working in my father’s lab, I became entrenched in the science of SMA and started to learn that the field was on the verge of a huge breakthrough. I knew I had to start filming the community and follow the events as it lead up to new discoveries in the field. Then I met Miles and his family.
Miles is a five year old boy with type II SMA. Like many SMA families, his parents, Nikki and Tony, were shocked by the diagnosis but fought to find an experimental treatment for their son. Following the family into a clinical trial, I saw how their story embodied the hope and struggle all SMA families go through when faced with the disease. Miles enrolled in a clinical trial and began taking an experimental drug to help treat his disease, which would later go on to be the first FDA approved drug for SMA. This disease has gone from an orphan disease with nearly nothing known about it, to now having its first FDA approved drug on the market, as well as other treatments in the pipeline. This incredible achievement represents the dedication of a community towards finding a treatment. The film represents what can be accomplished when families, researchers, and pharmaceutical companies join together to solve complex diseases. | medical |
http://mortlanddentistry.com/new-patients/ | 2021-06-15T17:17:30 | s3://commoncrawl/crawl-data/CC-MAIN-2021-25/segments/1623487621450.29/warc/CC-MAIN-20210615145601-20210615175601-00354.warc.gz | 0.951669 | 106 | CC-MAIN-2021-25 | webtext-fineweb__CC-MAIN-2021-25__0__96288567 | en | We are so glad you have chosen us for your dental care.
For your convenience, we have made available the two forms you will need for your first appointment with us. Just click on the PDF forms below, print them, fill them out, and bring them in with you.
Also, on the New Patient Information Form it asks that you have read and understood our Billing Policies and Privacy Practices. You may read them here:
Thank you. We look forward to seeing you!
Mortland Dentistry Team | medical |
https://www.vibrantlivingacu.com/ | 2024-03-02T12:41:05 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947475825.14/warc/CC-MAIN-20240302120344-20240302150344-00031.warc.gz | 0.922025 | 536 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__17114677 | en | Chet Franklin Acupuncturist
Currently closed due to Covid Pandemic.
About Chet Franklin, EAMP
Chet strives to be accepting and welcoming of people from all walks of life. He has a history working with the LGBTQ+ population, folks with acute and chronic injuries and multigenerational families. Chet's experience has led him to work with people at all ages from acupuncture at senior centers in Portland to learning acupressure for newborns in China. It is Chet's goal to make everyone feel comfortable through an open mind, a listening ear, and a gentle acupuncture style. He enjoys treating acute and chronic pain, digestive issues, auto and sports injuries, and much more.
Masters Degree- Masters of Science in Acupuncture and Oriental Medicine from the Oregon College of Oriental Medicine
Continuing Education - Study Abroad in China at the Nanjing University of Chinese Medicine
How I Can Help You
Prevention & Wellness
Sleep and Energy
Acupuncture: What to Expect
Before any acupuncture needles are inserted, Chet takes his time to make a diagnosis through palpating muscles and acupuncture points. Acupuncture needles are very thin and most people feel little to no pain with insertion. After needles are inserted, the patient is either left to rest, or a number of other modalities might be used. Shiatsu Massage, cupping, gua sha or moxibustion might be used for part the treatment if needed.
Shiatsu Massage: is like acupressure using the acupuncture points and channels to create harmony in the body without the use of any needles!
Cupping: uses glass cups to create suction to relieve pain and loosen tight muscles, and increase blood flow
Gua Sha: uses a tool to deeply rub the muscles to relieve pain, relax muscles, and increase blood flow
Moxa: is a Chinese herb that is burnt for it's deep penetrating heat to warm acupuncture points.
Most people find acupuncture to be very relaxing; and there is no need to be nervous about the needles before an appointment. If it was really painful, people wouldn't keep coming back for more!
Now accepting Motor Vehicle Accidents Claims, Regence BCBS, Humana, Aetna, Providence, United Health Group, Kaiser, Healthnet and Cigna!
If your insurance isn't listed above I am happy to provide you with a super bill which will allow you to get reimbursed by your insurance company for services rendered. This allows you to use your insurance for acupuncture even before Chet is able to bill your insurance company directly. | medical |
https://www.kwanza.fr/inproduction/mind-forward | 2020-07-11T05:29:12 | s3://commoncrawl/crawl-data/CC-MAIN-2020-29/segments/1593655921988.66/warc/CC-MAIN-20200711032932-20200711062932-00031.warc.gz | 0.945349 | 230 | CC-MAIN-2020-29 | webtext-fineweb__CC-MAIN-2020-29__0__209403205 | en | For the first time ever, it’s possible to understand the mysteries of the most complex and mysterious part of our universe: the human brain. In-depth understanding of the human brain opens doors to spheres which were until recently considered as belonging to the realm of science fiction: reading people’s minds, modifying their memories and behaviour, or sharing emotions over the internet….
Thanks to the unstoppable evolution of brain-machine interfaces, paralyzed patients can walk again with the support of an exoskeleton, and patients with brain damage, autism, or hyperactivity can improve their abilities. A quadriplegic patient can even drive a Formula 1 car just by using his brain.
But the potential offered by these brain-machine interfaces will soon also be applicable in the daily lives of people who wish to increase their cognitive skills, develop their aptitudes in mathematics, or improve their memory.
We are about to experience an unprecedented revolution, that of neurotechnology. We shall enter an era where neurorights will be key considerations, as it will be essential to regulate the privacy of our minds or the possibility of boosting our mental skills. | medical |
https://qmb.org.nz/qmb-satellite-cancer/ | 2019-03-24T17:16:40 | s3://commoncrawl/crawl-data/CC-MAIN-2019-13/segments/1552912203464.67/warc/CC-MAIN-20190324165854-20190324191854-00453.warc.gz | 0.920892 | 183 | CC-MAIN-2019-13 | webtext-fineweb__CC-MAIN-2019-13__0__177952125 | en | QMB Satellite CANCER
26-27 August 2018, Rydges Hotel
This meeting will be run in association with the Garvan Institute in Sydney. It will be focussed mainly on cancer (of course) with a session on new advances in clinical oncology and genomic medicine and will include advances from the lab covering cell signalling and cell:matrix interactions, tools and technology for understanding cancer and advances in immunoncology. We have a sensational balance of New Zealand and Australian speakers (four from the Garvan), senior and up and coming stars and have concentrated on maintaining the gender equity balance. It should be a fantastic opportunity to network and collaborate with peers in NZ and beyond particularly strengthening relationships over the ditch. The champagne breakfast tradition will continue!
You may also be interested in the New Zealand Society for Oncology meeting being held in Queenstown 24-25th Aug, 2018. | medical |
http://lets-jam.com/ | 2021-08-03T04:25:23 | s3://commoncrawl/crawl-data/CC-MAIN-2021-31/segments/1627046154420.77/warc/CC-MAIN-20210803030201-20210803060201-00586.warc.gz | 0.929033 | 894 | CC-MAIN-2021-31 | webtext-fineweb__CC-MAIN-2021-31__0__176876262 | en | The term Antisocial Personality Disorder or ASPD for short, refers to a chronic mental condition involving a pattern of disregard for the rights of others including the violation of other’s rights. Deceit and manipulation are common features of this personality disorder.
Personality disorders refer to mental health conditions related to the way a person feels, thinks, perceives or relates to others. Antisocial personality disorder is a pretty difficult personality disorder as the behavior of people with this disorder might be irresponsible, manipulative, impulsive, reckless, and indifferent to other’s feelings. Most often this personality disorder will lead to criminal behavior.
In DSM 5 it is included in cluster B, called emotional, dramatic and erratic cluster. The disorders in cluster B are characterized by problems with emotional regulation and impulse control.
This cluster also includes disorders such as Histrionic Personality Disorder, Narcissistic Personality Disorder, Borderline Personality Disorder and of course Antisocial Personality Disorder.
In ICD 10 it appears under the name of Dissocial Personality Disorder. The criteria are similar in both manuals (ICD – 10 and DSM – V) but not identical.
In both manuals it is mentioned that the antisocial personality disorder was often referred to as sociopathy or psychopathy and it might include psychopathy and sociopathy. But the two terms are not recognized or used by professionals to label diagnostics of antisocial personality disorder.
The diagnostic criteria for antisocial personality disorder were based on the work of Hervey Cleckley on psychopathy. Anyway there were critics who argued that as long as the criteria are not exactly the same, the antisocial personality disorder and psychopathy cannot be treated the same way.
Psychopathy is described as a personality disorder defined by traits that includes diminished ability for remorse, antisocial behavior and poor behavioral controls.
Most often psychopathy traits are measured using PCL-R (Psychopathy Checklist Revised), developed by Canadian researcher Robert D. Hare. Psychopathy diagnosis appears nowhere in the DSM or ICD though sometimes distinctions between the antisocial personality disorder and psychopathy or sociopathy are stated.
The spectrum of severity of antisocial personality disorder might range from a mild form that includes occasional bad behavior to a more severe version where the people with the disorder commit serious crimes and break the law repeatedly.
Robert Hare insists that his PCL-R is better than ASPD when it comes to predicting future violence and criminality though ASPD diagnosis covers twice or even three times more prisoners than psychopathy diagnosis.
In DSM – V psychopathy was proposed as an alternative model of ASPD, called Alternative DSM – 5 Model for Personality disorder. It is a diagnosis of ASPD with psychopathic features and it is described as the lack of fear or anxiety and bold interpersonal style that could mask fraudulence.
Five Subtypes Of ASPD Were Proposed By Theodore Millon:
- Nomadic – with avoidant and schizoid features.
- Malevolent – with paranoid and sadistic features.
- Covetous – feels deprived and denied and finds more pleasure in taking than having.
- Risk-taking – with histrionic features.
- Reputation defending – with narcissistic features.
- Male are more likely to be diagnosed with ASPD than women and people with ASPD are at higher risk of a violent death.
Also There Are Few Disorders That Are Very Likely To Coexist With ASPD Including:
- Anxiety disorders.
- Impulse control disorders.
- Depressive disorders.
- Borderline personality disorder.
- Narcissistic personality disorder.
- Somatization disorder.
- Substance related disorders.
- Sadistic personality disorder.
- Histrionic personality disorder.
The factors that might cause ASPD include imbalance between levels of testosterone, cortisol and serotonin. The three substances aforementioned seem to be important regulators of social aggression.
Other factors might include head injury, limbic neural maldevelopment, home and social environment or even cultural influences. Also there are scientists who think the ASPD might be inherited.
The ASPD should be diagnosed only by a trained psychiatrist and in order to understand this disorder people should seek the specialist help of a psychiatrist.
The treatment for ASPD is really difficult as the patient lacks remorse and the symptoms include deceitfulness. The most common treatment for ASPD are psychotherapy and cognitive behavioral therapy. | medical |
http://rawblogxport.blogspot.com/2008/12/wal-marts-2009-health-care-plan.html | 2017-04-28T21:36:48 | s3://commoncrawl/crawl-data/CC-MAIN-2017-17/segments/1492917123097.48/warc/CC-MAIN-20170423031203-00123-ip-10-145-167-34.ec2.internal.warc.gz | 0.939972 | 147 | CC-MAIN-2017-17 | webtext-fineweb__CC-MAIN-2017-17__0__279846836 | en | Wal-Mart's 2009 Health Care Plan Includes 'Debbie Shank Exception'
- International Business Times, NY
Many company health care plans include the legal right to subrogate or reclaim medical expenses paid by a health care plan if the patient wins money in a legal settlement. The right is rarely if ever exercised by companies in tragic cases such as Debbie Shank's.
The policy change may prevent Wal-Mart from putting another family through the agony it caused the Shanks. Ultimately, the decision to pursue subrogation still remains with Wal-Mart's health care plan administrative committee, but Wal-Mart may choose to apply the exceptions liberally rather than risk the kind of public relations debacle it incurred by going after Debbie Shank. | medical |
https://drchiragthakkar.com/blog/chronic-pancreatitis-pancreatic-stones-overview-investigation-and-treatment-ahmedabad-gujarat-india/ | 2024-02-26T10:04:04 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947474659.73/warc/CC-MAIN-20240226094435-20240226124435-00639.warc.gz | 0.946115 | 2,152 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__115776804 | en | As the name suggests it is a condition in which there is a long term inflammation of the pancreas. The pancreas is a digestive organ located in the upper part of your tummy, below your liver and behind the stomach. It produces the digestive enzymes needed for digestion of food and the hormones including Insulin needed to control the blood sugar levels.
Chronic pancreatitis develops slowly over time and leads to irreversible damage to the pancreatic tissue. The pancreas gets so much damaged, that it becomes hard and shrunken. During this process, the duct of the pancreas becomes narrow and strictured at one or multiple places. Especially near its opening in the intestine, ultimately leading to stone formation in the pancreatic duct. This leads to the failure of normal emptying of the pancreatic digestive juices in the intestine after a meal. Eventually, the whole duct dilates and is filled with stones.
The inflammation is triggered by alcohol intake and smoking in predisposed patients. Other reasons for this chronic inflammation of the pancreas are genetic factors, autoimmune conditions, nutritional factors. In a certain group of patients, the cause of pancreatitis remains unknown.
The hallmark symptom of chronic pancreatitis is abdominal pain. Pain is chronic and intermittent initially, which over time becomes more frequent or even constant. It is severe stabbing in nature, localized to the upper part of your tummy between your navel and chest. The pain may radiate to the back and is often triggered by eating, especially high fat foods. Pain after eating occurs as the digestive juice secreted by the pancreas to digest the meal gets entrapped inside the pancreas causing increased pressure in the duct.
With time the pain becomes more severe and debilitating. In some cases, it may become constant. Constant pain occurs due to the entrapment of the nerves in the hard and inflamed pancreas. Some of these patients take painkiller tablets every day and may need repeated injections as well to control their pain. For many patients, this pain is so debilitating that they are not able to lead a normal life.
When the pancreas doesn’t work properly, it affects the body’s ability to digest the food properly. Hence some patients of chronic pancreatitis do not get the required nutrients from the food they eat. This leads to the problem of malnutrition, leading to weak bones and vision loss. Patients may struggle to gain or maintain their weight.
Oily foul smelling bowel movements and weight loss may be seen in the advanced stages of chronic pancreatitis. It indicates that the pancreatic tissue that is actively functional for your digestion is very less.
Patients may also develop diabetes due to the loss of pancreatic tissue and may need insulin to maintain a good blood sugar control.
Some patients of chronic pancreatitis develop jaundice. The lower part of the bile duct goes through the pancreas. And sometimes as the pancreas becomes hard and shrunken, it compresses the bile duct. This leads to the blockage of the bile flow from the liver to the intestine and causes jaundice.
Another complication of chronic pancreatitis is pseudocyst formation. Due to persistent blockage and increased pressure in the pancreatic duct, there is a leakage of pancreatic juice from the duct. Leading to damage to the surrounding area and the formation of an infected cystic-like structure.
In some patients, there is clot formation in the portal vein. The Portal vein is located just behind the pancreas and in some patients, pancreatitis may cause direct damage to this vein. Portal vein thrombosis may lead to splenomegaly and vomiting of blood.
Blood tests are usually not helpful in the diagnosis of chronic pancreatitis. Serum Amylase is normal in most patients, except if there is a superadded episode of acute pancreatitis.
A CT scan will show that the pancreas is shrunken and the pancreatic duct is dilated. It also shows that stones are formed within the tube. Some patients may have stone formation even outside of the duct in the pancreatic tissue or the side branches of the duct.
Information about the other complications of chronic pancreatitis like, leakage of duct and pseudocyst formation, blood clot formation in portal vein and enlargement of spleen are also obtained from a CT scan. As these complications may change the treatment plan, knowing about them is very important.
MRCP is a specialized MRI done to see the details of the dilated pancreatic duct, stones in the duct and the side branches of the duct. It also gives information about the bile duct, weather it is dilated or not. Details that we get in an MRCP are very very important in the planning of treatment in chronic pancreatitis.
The primary goal of treatment is to achieve long-term pain relief, maintain nutrition, to slow down the further progression of the disease, control of the complications associated with the disease, and to restore the quality of life. Triggers like alcohol, smoking, and certain drugs should be avoided to prevent further damage to the pancreas.
Good pain management is a very important part of treatment. This includes oral painkillers like NSAIDs, narcotic medications, injectable medications and interventional procedures like celiac nerve blocks.
Pancreatic enzyme supplement and avoidance of high fat food are also measures to control pain. These measures are also important from the nutritional point of view.
In cases, when there are pancreatic duct stones and narrowing, the stones need to be removed and drainage of pancreatic juice should be established. Removal of the stones and relieving the block and establishing a good flow of the pancreatic juice in the intestine does slow down further damage to the pancreas. This helps in preventing further complications and the development of advanced chronic pancreatitis. It can be achieved by an endoscopic procedure called ERCP or by a formal surgery.
In this procedure, an endoscope is passed through your mouth to the part of the intestine where the duct of the pancreas opens. Then a guidewire is passed from this opening into the duct. Once a guidewire is in place, a dilator is passed over this wire to dilate the duct at the site of narrowing or structure. Stones are removed with the help of a balloon catheter.
Many a time ESWL, that is external shock ware therapy is used before doing this endoscopic treatment, to break the stone (similar to the ones done for kidney stones). It the end, a stent is placed in the duct, which needs to the exchanged repeatedly as necessary for about 1 year.
In a selected group of patients with less load of stones and smaller stones and less number of narrowing or blockage, this should be the first line of treatment. The patients who respond well to this procedure can be saved from surgery.
ERCP is now a standard procedure and gives good results in many patients. But we should keep in mind that even if it is a minimally invasive treatment option, it still does have its own risk. Especially when it is needed to be repeated multiple times.
Surgery is the last resort for patients who are troubled in spite of maximum medical management and endoscopic treatment.
All those patients who had undergone an ERCP and stenting, but are still having episodes of pain even after 6-8 weeks of stenting should consider surgery for better relief of pain and improvement in the quality of life.
Those patients who had undergone multiple endoscopic stenting and still need more stent exchanges should also consider surgery as a more preferred and an onetime solution to their problems.
Patients who have advanced chronic pancreatitis, having complications like jaundice, portal vein thrombosis or pseudocyst are the right candidates for surgery.
The type of surgery varies depending on the severity of the problem and the associated complications.
For most of the patients, the surgery includes the opening of the whole duct of the pancreas, removal of all the stones, removal of a small portion of the pancreas from the head of the pancreas and attaching the whole duct to the intestine. This surgery is called Frey’s procedure.
The history of the evolution of this surgery gives us the understanding that doing anything less than this does not give complete long term relief of pain. For example, if the tail part of the duct is not opened or the tissue from the head part is not removed, or if the stones from the side branches of the duct are not removed then the results are inferior. This is because in such a case some part of the pancreas is not drained, and the digestive juice from this part still remains trapped, and cause inflammation and pain.
And this is the exact reason why with ERCP multiple procedures and stent exchanges are needed. Because the drainage to the juices is provided by a 10 f stent which is just the size of refill of our pen. While in surgery the whole duct is opened to intestine creating a very wide opening. This new opening is not likely to be blocked again and further formation of stone is unlikely if the surgery is done in a proper way.
Although surgery is a major undertaking when done after thorough evaluation and in a proper manner, the risks are minimal and give excellent long term results. Pain free life, good nutritional status and good quality of life.
For deciding the treatment option, the success rate should be weighed carefully against the number of procedures required to accomplish and maintain this success rate and the risk of complications associated with these procedures.
According to Cochrane study which compiles all the studies does throughout the world, Endoscopic drainage seems inferior to surgery in symptomatic patients with advanced Chronic Pancreatitis.
You should consult a specialist to figure out what is the best treatment plan for you. The specialist will decide your treatment depending on your age, the severity of your pain, whether you have developed diabetes or exocrine enzyme deficiency and other complications of chronic pancreatitis. With timely and proper treatment, a patient of chronic pancreatitis can lead a normal and pain free life.
Listen to a few of our patients who fought the battle against chronic pancreatitis by clicking the below link
Hope this information was helpful to you in some ways. Any further queries or concerns you can call us or send you reports to us on 8156078064/07929703438 or mail us on [email protected] | medical |
http://resilienttheband.com/brainfest-2016/ | 2017-09-19T20:46:59 | s3://commoncrawl/crawl-data/CC-MAIN-2017-39/segments/1505818686034.31/warc/CC-MAIN-20170919202211-20170919222211-00155.warc.gz | 0.948343 | 1,172 | CC-MAIN-2017-39 | webtext-fineweb__CC-MAIN-2017-39__0__97831002 | en | We are pumped to be hosting BrainFest again this year on May 21 at the place where it all started for half of us: The Bridgeport Ribhouse.
This cause is very close to our hearts and has made us who we are as a band.
For those of you that don't know our story or the whole story of BrainFest, here's a bit of background...
In October of 2013, we had just gotten started jammin together and we were all going through a lot in our lives individually. This band seemed to be the glue that held everything together and kept us from falling apart. We had barely even started playing shows and figuring out a full set--let alone a name. One night, after what was supposed to be a random routine doctor's appointment, Erin showed up to practice to slowly break the news that would change everything: they found what they had deemed to be a "signal abnormality" in her brain, and suspected it to be a tumor in its early phases. The docs told her she would be transferred to The Hospital of the University of Penn the following week to discuss options...
We finished out our shows for the month and canceled everything else for the next six weeks while they opted to perform brain surgery (more specifically, a craniotomy) to remove the tumor.
Not even a year prior, the Fox sisters' mother had also just recovered from a nearly inoperable brain tumor and they had also lost a close family friend (who happened to be Kate's first drum instructor) to glioblastoma – the deadliest kind of brain tumor. The situation hit them hard.
So while in the hospital, Erin told Katie that if she survived, she wanted to put on a benefit concert for those still suffering with brain tumors. Everyone hoped for the best and prepared for the worst and the surgery was a remarkable success.
That May, BrainFest was born. It's been held annually ever since and continues to grow.
BrainFest is dedicated to raising funds and awareness for the advancement in the understanding and treatment of brain tumors. The event has featured educational games, stories, raffles, prizes, and live music from some of the area's most talented local musicians and members of the brain tumor community of friends, families, and survivors.
All proceeds benefit the American Brain Tumor Association - the first and now the only national nonprofit organization in the United States dedicated to providing support services and programs to brain tumor patients and their families, as well as the funding of brain tumor research since 1973 (www.abta.org)
We'll be stepping up the FEST this year by also including an awareness walk at Bridgeport Memorial Park the morning of the event (visit hope.abta.org/brainfest to register)...
If you want to attend the walk, you can purchase tickets in advance by visiting the link above. Be sure to wear comfortable clothing and suitable walking shoes. We'll have special prizes for our walkers as well! BONUS points if you show up wearing GREY!
We have also offered ticket packages for those who wish to attend both the walk and the festival. This includes a discount for child attendees.
You can also join the facebook event here: BrainFest 2016
This year's outreach also includes a community-wide dine-and-donate during fest weekend in support of BRAINFEST. To learn more about how you can participate, send your info to [email protected]
Thanks to the American Brain Tumor Association, the lives of those with a diagnosis are changing every day. Support and donations from the last year alone has enabled them to provide the first clinical practice guidelines for adult and pediatric brain tumor patients, fund 35 research studies in the U.S. focusing on brain tumors, and provide personalized information and support to over 3,500 patients and family members (just to name a few). There are nearly 700,000 people in the U.S. living with a brain tumor and nearly 14,000 will lose their battle this year. Brain and central nervous system tumors are also the most common cancers among children ages 0-19.
Every research dollar is critical and counts towards the discovery of new and improved treatment options.
More importantly, even the smallest amount of awareness can save a life.
BRAINFEST 2016 - Artist LineupWinkle & The Wanderers Resilient Alright Junior Work Release Sweet Eureka Civil Discord Adrastea London Calling! Red Means Run More Than Sound Canadian Tuxedo Revolution, I Love You The MP3s Mesa Jane School of Rock Philly Fort Washington School of Rock
Folks are asking, "how else can I help?" "how can I show my participation?"
Well there are lots of ways you can do this. Every bit of awareness is important in an effort as large as brain tumor research/treatment.
Any amount of support is deeply appreciated whether it’s a raffle donation, volunteering, advertising, your attendance at the festival, or just simply by spreading the word.
Every research dollar counts towards the discovery of new and improved treatment options and even the smallest amount of awareness can save a life.
This year, we hope to raise at least $10,000 for the ABTA, so we hope you can come to the fest and/or donate what you can to help us reach our donation goal in support of brain tumor research and cures.
Thanks for reading!
And don't forget to go grey in MAY!
To become a part of BRAINFEST, email [email protected]
BRAINFEST in the news:
American Brain Tumor Association:
Keep in the loop: | medical |
https://www.tutelaminorum.org/the-commission/former-members/professor-sheila-baroness-hollins/ | 2022-11-27T04:48:20 | s3://commoncrawl/crawl-data/CC-MAIN-2022-49/segments/1669446710192.90/warc/CC-MAIN-20221127041342-20221127071342-00661.warc.gz | 0.958214 | 335 | CC-MAIN-2022-49 | webtext-fineweb__CC-MAIN-2022-49__0__224268261 | en | Professor Sheila Baroness Hollins
Crossbench Peer in the House of Lords, Chair of British Medical Association Board of Science
Prof. Sheila the Baroness Hollins (England, currently living in London) has worked as a psychiatrist and psychotherapist with children and adults with intellectual disabilities including those who have been sexually abused, and is a life peer in the House of Lords.
Baroness Hollins was born in England and is married, with four children and four grandchildren. Sheila is an independent crossbench peer in the House of Lords, Chair of the Board of Science of the British Medical Association, Emeritus Professor of Psychiatry of Disability at St George’s University of London, and Honorary Professor in the Department of Theology and Religion at the University of Durham. She has received honorary doctorates in Medicine, Divinity, Science and Laws, and the Bronze medal of the Institute of St Martin in Florence for her work in the disability field. She has been a clinical specialist, researcher and policy maker in mental health and published both scientific papers and accessible patient materials on the subject of abuse and mental health. In 1989 she founded the long running Books Beyond Words series of picture books for non readers which includes two picture books on sexual abuse. Sheila has also served as Chair of the World Health Organisation Euro Steering Group on the health and wellbeing of children with intellectual disabilities (2008), President of the Royal College of Psychiatrists (2005-2008) and President of the British Medical Association (2012-2013). In 2011 she was assistant to Cardinal Cormac Murphy O’Connor during the Vatican Visitation to the Diocese of Armagh in Ireland. | medical |
https://theblacktruffle.com.au/stories/how-herbal-teas-can-improve-your-health | 2022-05-27T12:21:38 | s3://commoncrawl/crawl-data/CC-MAIN-2022-21/segments/1652662647086.91/warc/CC-MAIN-20220527112418-20220527142418-00228.warc.gz | 0.959422 | 1,329 | CC-MAIN-2022-21 | webtext-fineweb__CC-MAIN-2022-21__0__316759788 | en | 01 Jun 2017
Love tea? So does Emma Watson, naturopath and co-owner of Melbourne-based organic tea business, Love Tea. Here, Emma explains the Love Tea story and the health benefits of drinking herbal brews.
TBT: What’s separates Love Teas from others on the market?
EW: We believe products that are the best for your health are the ones that have no hidden ingredients and no unnecessary additives or flavours. We choose to use high quality, certified organic ingredients, sourced directly from around the world.
We also fairly source the majority of our ingredients directly from the growing communities and cooperatives who produce them. We pay fair trade premiums for the ingredients purchased from fair trade farms and continually strive to learn more about the challenges that the producers face.
And we are dedicated to donating one per cent of our annual net revenues to a range of environmental organisations worldwide. We feel it is our responsibility to reduce our negative impact on the environment, and we continue to support not-for-profit environmental organisations that are working towards improving the natural environment.
TBT: I hear you’re a qualified naturopath. How did your interest in health science lead to the creation of Love Tea?
EW: From a young age, I knew I wanted to help people improve their health. To me, naturopathy was a great way to do this, working with herbs, and natural medicine to help improve and optimise peoples’ health and help them achieve their individual goals.
I studied at Endeavour College of Natural health for 5 years and received my Bachelor degree in Health Science, Naturopathy. I started working with herbs and blending teas in my second year of university, and after a lot of trial and error, Love Tea was born.
The business grew quickly and my partner Damien Amos jumped on board to help take care of Love Tea, allowing me enough time to complete my course. He had great knowledge of herbs, organics and a desire to create products which had the least amount of negative impact on the environment.
TBT: What are the key health benefits of drinking herbal tea and how regularly should people drink them?
EW: Our wellness range was designed to support common health conditions, using organic herbs which have traditionally been used to improve these conditions, or reduce the severity of the condition. These blends focus more on a prevention rather than a cure and have been designed to improve overall function of a specific condition, or system, when taken regularly, in conjunction with a healthy diet and lifestyle. Each blend is completely unique and with 72 products in the range, there really is something for everyone.
Aside from the therapeutic benefits of individual ingredients, tea offers so many amazing health benefits. Tea is well-known for its antioxidant levels, but dependent on the individual spice, herb or tea, other health benefits can include anti-inflamatory qualities, digestive support and circulatory stimulant among many others.
The key is to become aware of your weaknesses and bring herbs and teas into your diet, that can offer the support you specifically require. We recommend two to three cups per day, at least 30 minutes either side of food so as not to compromise digestive function.
TBT: What should people be warry of when buying herbal teas?
EW: Additives, flavours and sweeteners. Some people fall in love with the taste of a tea and think they are doing their body wonders. Sometimes what they are drinking is closer to a cordial then to a tea. It’s super important to read the ingredients and check what is in a tea – don’t assume it will always be tea, herbs and spices!
The other important point to me is that your tea is certified organic. If there is only one thing you choose to buy organic, let it be tea not just because it tastes better, and it’s better for the planet, but also because you steep the tea in the water you are going to consume. This means you’ll ultimately be drinking whatever chemicals were sprayed onto the ingredients when they were grown.
By choosing organic ingredients, you ensure your tea is as close to its natural state as possible – pure and clean, and free from chemicals.
TBT: Winter is here and that means cold and flu season is upon us. What tea should people drink to ward off these nasty viruses?
EW: The beauty of tea is that there really is something for everyone and therapeutically speaking, different blends are more appropriate at different times of the year. Right now, while temperatures are still cool and the seasons are changing, our Immunity tea is our top pick.
This blend has been naturopath-designed to strengthen and support healthy Immune function. Herbs used in this blend including Echinacea have traditionally been used to enhance immune system function and help reduce the severity of the common cold or flu. We have combined this wonder herb with ginger, which offers circulatory support and nettle, which is nutrient-rich, to strengthen the immune system.
This grounding blend also includes lemon balm, supporting the adrenal glands, which are often depleted by stress and fatigue. We believe supporting the nervous system at this time is essential, as stress is often a contributing factor to colds and flus.
TBT: And what about insomnia? I hear herbal tea can be very beneficial to those who struggle to sleep?
EW: A herbal tea can be amazing for the treatment of insomnia. It offers a non-invasive and gentle approach to treating a condition that can have a hugely negative impact on someone’s life, if left untreated.
We designed our Sleep tea specifically to help calm the nervous system and to promote deeper, more rejuvenating sleep. This blend is completely caffeine free and is based on a combination of herbs that work together to relax and calm the mind, and body, including lavender, valerian, passion flower and chamomile. A hint of mint and liquorice bring a lightness and a subtle sweetness, making it a grounding and tasty nightly ritual before bed.
TBT: What’s your favourite blend?
EW: Very hard question! My favourite teas would have to be our Digestive tea and our Liquorice Love. Both of these blends are slightly sweet from the Liquorice and really refreshing.
Damien’s’ favourite blend is the Australian Sencha. This is a light green tea, grown in northern Victoria. | medical |
https://beyondthesave.org/find-help | 2021-01-18T22:06:25 | s3://commoncrawl/crawl-data/CC-MAIN-2021-04/segments/1610703517159.7/warc/CC-MAIN-20210118220236-20210119010236-00011.warc.gz | 0.933895 | 903 | CC-MAIN-2021-04 | webtext-fineweb__CC-MAIN-2021-04__0__121843274 | en | Our consortium member NorthCare Network purchased a subscription for the digital behavioral health app myStrength that can be used by anyone in the UP. myStrength offers custom resources to improve mood and overcome the challenges your clients face. Track health, enjoy interactive activities, and become inspired by quotes and videos with myStrength. You can download the app on iPhone or Android.
Use the code NCNcommunity to access
Dial Help's Safety Net Program (SNP) is available UP-wide. It provides follow-up support for people dealing with suicidal thoughts, loss of a loved one to suicide, complex crisis, or Substance Use Disorder. Support includes assessing emotional state, safety planning, connection to resources, and more. Clients can choose whether they want to be contacted by phone call or text message.
If you have a client who would like to enroll in the SNP, please contact Dial Help at 906-482-9077 with the client, or via three-way call.
Peer recovery coaches walk side by side with individuals seeking recovery from substance use disorders. They help people to create their own recovery plans, and develop their own recovery pathways. Recovery coaches provide many different types of support, including emotional (empathy and concern), informational (connections to information and referrals to community resources that supportnhealth and wellness), instrumental (concrete supports such as housing or employment), and affiliational support (connections to recovery. Email [email protected] to find a local recovery coach.
Dial Help is a non-profit crisis center serving the Upper Peninsula. Their mission is to promote the physical, emotional, and social well-being of our communities. We accomplish this goal by providing problem assistance, crisis intervention, referrals, education, and training.
Dial Help offers a 24/7 crisis line, and a Safety Net Program providing follow-up support and treatment service navigation via phone call or text message.
NorthCare Network is one of Michigan’s ten Prepaid Inpatient Health Plans (PIHPs) responsible for the management of various sources of State funding. Their mission is to ensure that every eligible recipient receives quality specialty mental health and substance use disorder services and supports through the responsible management of regional resources.
NorthCare provides a comprehensive array of specialty mental health and substance abuse services. This includes supports for adults with serious mental illnesses, children and adolescents with serious emotional disturbances, persons with intellectual/developmental disabilities, and persons with substance abuse disorders.
GLRC is a non-profit agency specializing in substance abuse and mental health treatment for youth, families and adults. Their mission is to empower recovery through hope and change. GLRC offers treatment services by certified counselors and licensed professionals, including residential and outpatient. They also provide peer recovery coaches; specialty youth, veteran, and women's services; and training in the community.
Narcan (also known as Naloxone) is a life-saving opioid overdose reversal drug available as an injectable or nasal spray. Through the Grand Rapids Red Project, Narcan/Naloxone is available free by mail anywhere in Michigan. This project is made up of community members who are passionate advocates and activists in the fight against HIV/AIDS, hepatitis, and accidental overdose. Click here for more information.
A public health approach that helps prevent communicable diseases, unsafely discarded needles, and accidental overdose. SSPs provide free, confidential supplies and services to those who use drugs, including syringe exchange and links to testing for HIV and Hepatitis, peer recovery coaches, and mental/physical health treatment. SSPs in Michigan are housed in your local Health Department. Click here to find a program near you. Click here for more information.
Connect UP - Rides to Wellness is a new transportation option for patients across the Upper Peninsula. If you require transportation for local or long distance medical/behavioral health appointments, please call our transportation hotline at Schoolcraft Memorial Hospital.
Leave a message at the Transportation Hotline 906-341-3753 to learn about qualifications for the program.
If you are a Meidcaid or UPHP plan member, please contact those providers for transportation information.
History: In 2019, Schoolcraft Memorial Hospital provided Schoolcraft County Transit Authority with a $10,000 Grant to offer Free Transportation to Medical and Mental Health Appointments. The grant period has ended but other options are available for patients seeking transportation assistance. | medical |
https://doctormahmed.wordpress.com/category/uncategorized/ | 2018-12-14T18:12:50 | s3://commoncrawl/crawl-data/CC-MAIN-2018-51/segments/1544376826145.69/warc/CC-MAIN-20181214162826-20181214184826-00100.warc.gz | 0.842391 | 2,314 | CC-MAIN-2018-51 | webtext-fineweb__CC-MAIN-2018-51__0__162792509 | en | A Biographical Sketch of Mohiuddin Ahmed
Citizenship: Naturalized US Citizen
Licensed as psychologist provider in Massachusetts and RI
Address: 57 Puddingstone Lane, Bellingham, MA 02019
Email: [email protected] ; [email protected]
o B.A. (Hons.) in Philosophy, Dhaka University, Dhaka, Bangladesh (1958).
o M.A. in Philosophy, Dhaka University, Bangladesh (1959).
o M.S. in Clinical Psychology, Long Island University, Brooklyn, New York (1963).
o Ph.D. in Clinical Psychology, University of Pittsburgh, Pennsylvania (1969).
Work Experience- Current
Psychologist: Metis Psychological Associates, LLC, 490 North Main, Randolph, MA 02368 (November, 2015-present)
o Consulting Psychologist, part-time, Community Care Alliance, Woonsocket, Rhode Island (November 2009-to-present).
o Adjunct Professor Department of Psychology, University of Rhode Island Kingston, RI(2004-to-present).
Past Work Experience
o Clinical Psychologist (part-time, providing services to nursing home clients), MedOptions, Inc., Behavior Health Services Provider, Old Say brook, CT (2010-2013).
o Consulting Psychologist providing group and individual therapy to adults and children, psychological evaluation and consultation (part-time) NRI Community Services Woonsocket, RI (1999-October 2009)Staff Psychologist (part-time) Taunton State Hospital, Massachusetts (2004-2009).
o Senior Psychologist (half-time), Taunton State Hospital, Massachusetts (1988-2002).
o Chief Psychologist (half-timed) NRICS, Rhode Island (1981-1999).
o Director, Outpatient Services, NRI Community Services (NRICS) Woonsocket, Rhode Island (1979-81).
o Chief Psychologist and Director, Community Evaluation and Rehabilitation Clinic (CERC), Wrentham State School, Massachusetts (1971-79).
o Lecturer, Philosophy Department, Dhaka University, Bangladesh (1960-61).
o Assistant Professor, Psychology Department, Ateneo De Manila, Philippines (1979-71).
o Lecturer (part-time), Psychology Department, Northeastern University, Boston, Massachusetts (1972-74)
Additional Work Experience:
- Private Practitioner as clinical psychologist (providing therapy, assessments, and consultation), Barrington Medical Center, East Providence, Rhode Island (1981-1988).
- Consulting Psychologist (part-time)Community Counseling Center, Pawtucket, Rhode Island (1983-1987).
- Consulting Psychologist (part-time),Family Resource Community Action, Rhode Island (2001-2002).
Other Consultation Experience
o Consultant Developmental Medicine Center, Formerly Developmental Evaluation Clinic, Children’s Hospital, Harvard Medical School, Boston, Massachusetts (1974-79).
o Consultant (assisting with program development in retardation in Bangladesh , under TOKTEN program of United Nations Developmental Program, 1991.
Research Project Involvements:
- Project Director: Behavior Training of Mentally Retarded and Behaviorally Disordered Filipino Children in Public Schools sponsored by Philippine Mental Health Association (1970-71)
- Project Director: Day and Residential Programs for Behaviorally Disordered Mentally Retarded Adults in Community sponsored by Wrentham Research Foundation in collaboration with Department of Mental Health and Retardation in Massachusetts (1976-79).
- Project Director: CMHC (NRI Community Mental Health Center)-Local Educational Authority (Catchment Area Public Schools) Collaborative Projects: pioneering home-based counseling, school-based counselingand clinic-based day school program, sponsored by the RI Department of Education (1980-1986).
- Project Director: Adaptation of the Multi-Function Needs Assessment Survey sponsored by Rhode Island Mental Health Advancement Resource Center (1996-97).
- Co-project Director with David Osser, MD: Long-term Follow up of clozapine treated hospitalized patients discharged to the community sponsored by Taunton State Hospital Research Committee in collaboration with Massachusetts DMH Research Committee. (CORRC 1998-2009).
Recently published a book in collaboration with Professor Charles Boisvert of Rhode Island College on a psychotherapy model, Mind Stimulation Therapy. Pioneered this model of psychotherapy for challenging mental health populations that was developed in his work experience over 40+ years of clinical practice in various practice settings with diverse clinical populations. The Mind Stimulation Therapy model was further refined and developed in his long-time collaborative work with Professor Boisvert, who was his former student-extern for six years at NRI Community Services.
See Mind Stimulation Therapy: Cognitive Intervention for Persons with Schizophrenia by Mohiuddin Ahmed and Charles Boisvert, Routledge, NY, 2013
Mohiuddin Ahmed, Ph.D., Harold J. Bursztajn, MD., Ronald Abramson, MD: Back to the Future. To be published in Psychiatric Services, May Issue, 2016.
Mohiuddin Ahmed, Ph.D., Harold J. Bursztajn, MD, Ronald Abramson, MD, Steven Nisenbaum, Ph.D.: An alternative name for schizophrenia. The Lancet Psychiatry, Vol 1, Issue 4, 2014
Mohiuddin Ahmed, PhD, Harold J. Bursztajn, MD, Beverly Jalil, Ahmad Newaz Khan, MD, and Reza Rahman, MD. Maintenance of recovery from severe psychotic depression following successful electroconvulsive therapy in an elderly patient with “natural support,” Journal of Clinical Geriatrics and Gerontology, July, 2014.
o Mohiuddin Ahmed, Ph.D, David N Osser, MD, Charles M Boisvert, Ph.D., Lawrence Albert, MD, & Masood Aslam, MD. Rationale for Emphasis on Management over Treatment of Schizophrenia in Clinical Practice, Annals of Pharmacotherapy, April 2007, 41:693-95.
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Using computers as visual aids to enhance communication in therapy, Behavior, September 2006, 5: 847-55.
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Using Positive Psychology with Special Mental Health Populations, American Psychologist May-June 2006, 333-5.o
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Exploring Unique Roles for Psychologists, American Psychologist, October 2005, 732-4.o
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Multimodal Integrative Cognitive Stimulating Therapy (MICST): Moving beyond the reduction of psychopathology in Schizophrenia, Professional Psychology: Research and Practice, December 2003, 34(6):644-51.o
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Enhancing Communication Through Visual Aids in Clinical Practice, American, October 2003,58(10) 816-19. o
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Cognitive Skills Group Treatment for Schizophrenia, Psychiatric Services, November 2002, 53911): 1476-7o
o Mohiuddin Ahmed, Ph.D. & Charles M Boisvert, Ph.D. Computer-facilitated therapy dialogue with persons with schizophrenia, Psychiatric, January 2002, 53(1): 99-100.o
o Mohiuddin Ahmed, Ph.D. Computer-facilitated therapy: Reality-based dialogue with people with schizophrenia, Journal of Contemporary Psychotherapy, 1999, 28(4): 397-403.
o Mohiuddin Ahmed, Ph.D., Franz Bayog, B.A., and Charles M Boisvert, Ph.D. Computer-facilitated therapy with inpatients with schizophrenia, Psychiatric Services, October 1997. 48(10): 13354-5.o
o Mohiuddin Ahmed, Ph.D. & Judith A Goldman, Ph.D. Cognitive Rehabilitation of adults with severe and persistent mental illness: a group model, Community Mental Health Journal, August 1994, 30: 385-394.
o Mohiuddin Ahmed, Ph.D. Behavior therapy with emotionally disturbed and retarded Filipinos children, Philippine Journal of Mental Health, 1973,4(2): 69-110.o
o Mohiuddin Ahmed, Ph.D. American Student Activism in Comparative Perspective, American Psychologist, 1971, 26(5): 514.o
o Mohiuddin Ahmed, Ph.D. & James F. Voss, Ph.D. Serial Acquisition as a function of Stage of Learning, Journal of Experimental Psychology, 1969, 82(2): 396-400.
o Mohiuddin Ahmed, Ph.D. & David N Osser, MD. Follow-up of Successfully Treated Clozapine Patients Over One Year After Discharge: A Performance Improvement Outcome Study. Harvard Medical School Department of Psychiatry Sponsored Seventh Annual Research Day, April 1999.o
o Mohiuddin Ahmed, Ph.D., William Disch, Ph.D., Mary Dwyer, MSN, & James Gilchrist, BA. A preliminary report on Needs Assessment and an Intervention Program at a Community Mental Health Center: Examination of the Psychometric Properties of the Multi-Function Needs Assessment Scale for Assessing Functional Status of Client Needs During an Intervention Program for Psychiatric Clients. Poster presented at a meeting sponsored by Rhode Island Mental Health Advancement Resource Center, June 1998.
Workshop and Other Presentations:
Mohiuddin Ahmed: Mind Stimulation for Adaptive Thinking, Feelings, and Behaving. Medway Public Library Public Education Presentation, October 8, 2015.
Mohiuddin Ahmed and Charles Boisvert: Mind Stimulation Therapy, Rhode Island Social Worker Association, and RI Mental Health Association, 2015, and 2014.
o Mohiuddin Ahmed, and Charles Boisvert, Cognitive Stimulation, Mindfulness Strategies, and Existential Perspectives in Group Counseling -A report on the adaptation of the Multimodal Integrative Cognitive Stimulation Treatment (MICST) with substance abuse populations23rd and 26th Cape Cod Symposium on Addictive Disorders,2010 and 2012o
o Mohiuddin Ahmed, Ph.D. New Techniques of Cognitive Treatment. Presentation at Research Symposium entitled, “Progress in Schizophrenia Research in the Southeastern Area,” Southeastern Area Research Committee of Massachusetts, Department of Mental Health, Brockton, November 1998.
Mohiuddin Ahmed, Ph.D. & Jackie Farese, MA. Affective and Values Clarifying Education and Group Therapy as Part of Daily Classroom Activities for the Behaviorally Handicapped Adolescents. Presentation at XIII International School Psychological Co | medical |
https://lilachomestead.com/how-to-make-a-sleep-inducing-valerian-herbal-tea/ | 2024-04-14T08:55:56 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296816875.61/warc/CC-MAIN-20240414064633-20240414094633-00170.warc.gz | 0.931879 | 1,426 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__99175597 | en | Valerian Herbal Tea for a Deeper, More Restful Sleep
Are you tired of tossing and turning at night? Do you struggle to fall asleep, even when you’re exhausted? You’re not alone. In fact, studies show that 50% of adults have trouble sleeping at some point in their lives. But there’s a natural solution that has been used for centuries to promote relaxation and support healthy sleep: valerian root.
This plant is powerful medicine for anyone looking to improve the quality of their sleep. In this article, we’ll explore the many benefits of valerian root tea and explain how you can make your own at home. By the end, you’ll have the tools you need to achieve a deeper, more restful sleep.
What is Valerian root and How Does it Work?
Valerian root is a natural remedy that has been used for centuries to promote relaxation and improve sleep quality. But what exactly is valerian root, and how does it work? Valerian is derived from the root of the valerian plant, which is native to Europe and Asia. The extract contains a number of compounds, including valerenic acid and isovaleric acid, which are believed to promote relaxation and calmness.
Valerenic acid has been shown to increase levels of GABA in the brain, a neurotransmitter that helps to regulate anxiety and promote relaxation. Isovaleric acid has a similar effect, helping to relax the muscles and reduce tension in the body. Together, these compounds work to create a calming effect on the mind and body, making it easier to fall asleep and stay asleep throughout the night.
In addition to promoting relaxation, valerian root has been shown to have a number of other benefits for sleep. These include reducing the amount of time it takes to fall asleep, improving sleep quality, and reducing the frequency of nighttime awakenings. Valerian may also help to regulate the sleep-wake cycle, making it easier to fall asleep and wake up at the same time every day.
Overall, valerian is a safe and effective natural remedy for improving sleep quality and promoting relaxation. Whether you’re struggling with insomnia, anxiety, or just looking to get a better night’s sleep, valerian can be a game-changer.
The Benefits of Valerian root tea for Sleep
In addition to promoting relaxation, valerian has been shown to have a number of other benefits for sleep. Research has found that valerian can significantly reduce the amount of time it takes to fall asleep and improve sleep quality. It has also been shown to reduce the frequency of nighttime awakenings, allowing for a deeper, more restful sleep. Valerian may also help to regulate the sleep-wake cycle, making it easier to fall asleep and wake up at the same time every day.
These benefits make valerian herbal tea an excellent choice for anyone looking to improve their sleep quality. And the best part? It’s a natural remedy with few to no side effects.
Next, we’ll explore how you can make your own valerian herbal tea at home using just a few simple ingredients.,
Valerian Root Tea Recipe
Valerian root tea is a popular herbal remedy for improving sleep quality. The fresh root is stronger than dried, but you can also use dried valerian root. While making your own valerian herbal tea at home is a great way to ensure its purity and potency, you can also buy the tea bags. Traditional Medicinals organic valerian tea is a lovely option.
Here’s what you’ll need to get started with making the tea from fresh root:
- Valerian plant- 1 year or more old
- Large bowl with warm water
- A teapot
- Filtered, almost boiling water
- A strainer or cheesecloth: You’ll need to strain the extract to remove any plant matter.
To make the tea, simply chop up your valerian root and place it in the teapot. Cover the roots with the filtered, hot water. Let steep overnight. Strain roots out with a strainer or cheesecloth after 12-24 hours and store leftover tea in the fridge.
You can compost the leftover plant matter. Your homemade valerian tea is now ready to use!
In the next section, we’ll explore some tips for using valerian extract safely and effectively.
Tips for Using Valerian Root Tea Safely and Effectively
Valerian has been used for centuries to promote sleep and relaxation, but like any other supplement, it’s important to use it safely. Here are some tips to keep in mind:
- Talk to your healthcare provider before taking any new supplement,
- Start with a low dose and gradually increase it as needed. Too much valerian can cause drowsiness, headaches, and upset stomach.
- Pulse valerian and take it for one month on, then 5-7 days off. Don’t take valerian for an extended period of time without taking a break.
- Don’t drive after taking valerian extract because it can cause drowsiness.
- Store valerian root in a cool, dark place away from children and pets.
By following these tips, you can safely and effectively use valerian root tea for sleep and relaxation. There are other natural remedies that can help improve sleep, such as chamomile tea and lavender essential oil. Let’s explore them next.
Other Natural Remedies for Better Sleep
By following the tips discussed earlier, you can use valerian root tea to achieve a better night’s sleep. Other botanicals that can help promote relaxation and improve sleep quality include lavender and chamomile.
Chamomile tea is well loved because it has a calming effect on the body. The tea contains a flavonoid called apigenin, which binds to specific receptors in the brain that promote sleepiness. Drinking a warm cup of chamomile tea before bedtime can help you relax and fall asleep faster.
Another natural remedy is lavender essential oil. Lavender has been shown to reduce anxiety and promote relaxation, making it a popular choice for improving sleep quality. You can add a few drops of lavender oil to a warm bath to promote relaxation. Use essential oils sparingly.
If you’re tired of tossing and turning at night, valerian root tea might be the natural solution you’ve been searching for. By promoting relaxation and supporting healthy sleep, this powerful plant can help you get the rest you need to feel your best. Making your own tea at home is easy and ensures that you’re getting a high-quality product that will provide maximum benefits. | medical |
https://thetigers.com.au/brisbane-tigers/tigers-turn-pink-for-kim-walters-choices/ | 2021-10-15T22:43:19 | s3://commoncrawl/crawl-data/CC-MAIN-2021-43/segments/1634323583087.95/warc/CC-MAIN-20211015222918-20211016012918-00021.warc.gz | 0.95951 | 994 | CC-MAIN-2021-43 | webtext-fineweb__CC-MAIN-2021-43__0__174980870 | en | Club Captain Matthew Zgrajewski models the Tigers Pink Strip.
Join us this Sunday 12 July at Tapout Energy Stadium for our Kim Walters Choices Day. The Tigers will be wearing special pink jerseys for their Round 18 Intrust Super Cup fixture against the Ipswich Jets.
The Club will be selling Kim Walters Choices merchandise, collecting donations and selling raffle tickets to raise much needed funds for The Kim Walters Choices Program. Choices is a free community service available to any individual diagnosed with breast or gynaecological cancers. Families and friends of those diagnosed are also welcome.
It will be a special day for the Tigers as Kim Walters’ sons Billy will be lining up for the Tigers in the Intrust Super Cup side at 1.40pm, whilst Jack will be playing for Normanby Hounds in the BRL A Grade fixture at 11.45am.
Come and help us get behind this great cause. We would appreciate your support.
The Wesley Hospital Kim Walters Choices Program (Choices) was launched in 1998, as a legacy of Kim Walters and her vision for support services for women diagnosed with breast cancer. Kim Walters was diagnosed with breast cancer in August 1996, whilst pregnant with her third child. She immediately underwent surgery to remove the cancerous lump in her right breast, but chose to delay chemotherapy until after the birth of her child, Jett. During and after the treatment phase of her breast cancer journey, Kim found great support from other women who had personally experienced breast cancer. Like so many others, Kim found a level of understanding and comfort with these women, which she believed greatly helped her on her journey. Sadly, Kim lost her 18-month battle with breast cancer in February 1998, at the age of 30. However, before she passed away, Kim expressed her desire to establish a community service which would provide help and support for other women with breast cancer. Kim’s dream became a reality on March 16 1998 when the Choices program was launched at The Wesley Hospital in Brisbane, by her husband, patron of Choices and former Brisbane Broncos captain, Kevin Walters. The Choices Program is a tribute to the courage and strength of not only Kim Walters, but also the countless other women who have experienced breast cancer. It provides support, counselling, information and therapies to women and men diagnosed with breast cancer, and their families.
The Wesley Hospital Kim Walters Choices Program
No one is ever prepared for breast or gynaecological cancer, but at The Kim Walters Choices Program (Choices) our experience helps us support you through the emotional turmoil and difficult decision making process following your diagnosis. We understand that everyone is different so we will work with you to select the aspects of our program that best suit you.
We offer you, your family and your friends access to a network of professionals, volunteers and others affected by breast or gynaecological cancer – who you choose to interact with is your decision. Our programs are offered free of charge to everyone (regardless of where you are receiving treatment) and they aim to improve the quality of your life.
You do not need a referral, just call us on 3232 6548 to make an appointment, to find out further information about how we can help, or to share your questions and concerns with us.
We are here to support you.
But how exactly does Choices help?
We offer a toll free hotline and a drop in facility for women, men, their families and friends to receive information, sharing, friendship and support. Choices’ inter-disciplinary team includes specialist nurses, peer support coordination, staff and volunteers with personal experiences of breast and gynaecological cancers, counselling and physiotherapy services – all who are expert in supporting families throughout their experience. This means those needing information are only a phone call or visit away from getting help from a friendly, professional team who can advise on everything from cancer treatment to wig fitting and everything in between, including:
- Help with making important decisions about surgery and treatment
- Connection with breast care nurses, women’s health nurses and peer support
- Coordination of support groups to bring together those who can share their similar personal experiences
- The provision of complementary therapies designed to counteract stress and provide relaxation
- Post-surgery exercise classes designed specifically to improve range of motion and strength after surgery
- Advice about broader life-related topics including stress management, sexuality and fertility issues, survivorship, menopause, exercise and nutrition
- Plus a diverse range of additional support services including but not limited to a rural and regional workshop program, wig and turban library, and community education presentations to schools, clubs and businesses
Choices is open from 8:30am to 5:00pm Monday to Thursday and from 8:30am to 2:30pm on Friday.
Telephone: 07 3232 6548 | medical |
http://qpmpa.org/aggregator/sources/2 | 2020-05-25T00:34:24 | s3://commoncrawl/crawl-data/CC-MAIN-2020-24/segments/1590347387155.10/warc/CC-MAIN-20200525001747-20200525031747-00360.warc.gz | 0.947991 | 557 | CC-MAIN-2020-24 | webtext-fineweb__CC-MAIN-2020-24__0__74752763 | en | French authorities reported the smallest daily rise in new coronavirus cases and deaths on Sunday since before a lockdown began on March 17, raising hopes that the worst of the epidemic is over in France.
The U.S. Centers for Disease Control and Prevention (CDC) on Sunday reported 1,622,114 cases of the new coronavirus, an increase of 26,229 cases from its previous count, and said the number of deaths had risen by 1,047 to 97,049.
Chile's healthcare system is under strain and "very close to the limit," President Sebastian Pinera said on Sunday, as the number of confirmed novel coronavirus infections approaches 70,000 after a rapid increase in recent days.
Americans sunbathed on beaches, fished from boats and strolled on boardwalks this holiday weekend, but the occasional person wearing a mask was a constant reminder that the world is still battling the coronavirus pandemic.
First indications of the effectiveness of a potential vaccine against coronavirus may be available in the autumn, the head of the GAVI vaccine alliance told a Swiss newspaper, forecasting a long road from there to broad availability.
China recorded three new confirmed COVID-19 cases on the mainland for May 23, following the first day with no new cases since the outbreak began, the National Health Commission (NHC) said in a statement on Sunday.
Mexican health authorities registered 3,329 new cases of the novel coronavirus in the country and 190 new deaths, a health official said on Saturday, bringing the total number to 65,856 cases and 7,179 deaths.
The University of Oxford's COVID-19 vaccine trial has only a 50% chance of success as the coronavirus seems to be fading rapidly in Britain, the professor co-leading the development of the vaccine told the Telegraph newspaper https://bit.ly/2LQTNos.
Coronavirus infection rates in France have slowed further and the number of COVID-19 patients in hospital and intensive care continued to fall, health ministry figures showed, a sign that social distancing is keeping contagion in check for now.
The U.S. Centers for Disease Control and Prevention (CDC) on Saturday reported 1,595,885 cases of the new coronavirus, an increase of 24,268 cases from its previous count, and said the number of deaths had risen by 1,852 to 96,002.
South America has become a new epicenter of the COVID-19 pandemic with Brazil hardest-hit, while cases are rising in some African countries that so far have a relatively low death toll, the World Health Organization (WHO) said on Friday. | medical |
https://darwinreconsidered.org/756/can-the-use-of-virtual-support-groups-for-chronic-illness-facilitate-emotional-support-and-disease-management/ | 2024-04-20T01:13:15 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296817463.60/warc/CC-MAIN-20240419234422-20240420024422-00243.warc.gz | 0.940936 | 1,380 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__13510354 | en | In our increasingly digital world, the influence of online communities on various aspects of our lives cannot be denied. One area that is witnessing an exponential surge in online presence is the health sector. Among the various facets of health, the management and support for chronic illness stand out as primary areas that have significantly benefited from the advent of online platforms. This article seeks to explore how virtual support groups can facilitate emotional support and disease management for patients living with chronic illnesses.
Peer support groups play an integral role in the management of chronic illnesses. These groups are formed by individuals who share similar health conditions, creating an environment of understanding and empathy. When these support groups transition online, they not only retain these characteristics but also bring in additional advantages.
Studies have shown that individuals with chronic diseases often feel isolated because of their condition. They experience a unique set of physical and mental challenges that may be difficult for others to comprehend. Online peer support groups provide a platform where they can express their feelings, share their experiences, and receive advice from people who truly understand what they’re going through. These groups foster a sense of belonging and help alleviate feelings of loneliness and depression.
An online support group isn’t limited by geographical barriers, enabling a larger community of people to connect and interact. This can be particularly helpful for individuals residing in remote areas or those who are unable to travel due to their condition.
Emotional support plays a vital role in managing a chronic illness. It has been observed that emotional health can directly impact the physical health and disease management of chronic illness patients. Online communities provide a much-needed platform for emotional support.
Members of online support groups can form deep connections despite the virtual nature of their interactions. The anonymity provided by online platforms can sometimes make it easier for individuals to open up about their struggles. These groups become a refuge where members can vent their frustrations, discuss their fears, and celebrate their victories, no matter how small.
Online communities also provide resources such as educational content, coping strategies, and personal experiences, all of which can enhance emotional resilience. Instant access to this plethora of information can help individuals better understand their condition and manage their emotional responses more effectively.
Chronic illnesses often require long-term management strategies that encompass a wide range of health behaviors, such as medication adherence, lifestyle changes, and symptom management. Here, social support, especially from peer groups, plays a pivotal role.
Online support groups provide a platform for members to share tips, strategies, and personal experiences related to disease management. These can range from suggestions on managing side effects of medications to tips on lifestyle modifications. The shared experiences and advice from peers can provide practical and valuable insights that medical professionals may not offer.
Studies have shown that online social support can positively influence self-efficacy and health behaviors. Participants in these online communities often report feeling more confident about managing their condition, which, in turn, leads to better adherence to treatment plans and improved health outcomes.
Time is a crucial factor when it comes to managing chronic illnesses. Regular check-ups, medication schedules, and lifestyle adjustments can all be time-consuming. Online support groups can aid in better time management.
Many online communities are accessible round the clock, allowing members to seek support and information at any time that suits them. This flexibility is particularly beneficial for those who may be working, attending school, or managing other responsibilities.
Members can also save the time spent on travelling to physical support group meetings. Plus, the continuous availability of online resources ensures that help is always at hand, even at odd hours.
Finally, the online communities can also assist in managing doctor appointments and medication schedules through reminders and shared calendars. This can be a significant relief for those who struggle with managing these aspects due to the cognitive impact of their disease.
In conclusion, while the impact of online communities on chronic illness management is multifaceted and complex, the evidence suggests that these platforms can indeed offer tangible benefits. They provide emotional and social support, aid in disease management, and contribute positively to time management. While they are not a substitute for professional medical care, they certainly provide an avenue for improved quality of life for those living with chronic illnesses.
The potential of virtual support groups for chronic illness management is immense. Their role extends beyond providing emotional support and disease management advice, they also serve as a conduit for information and knowledge sharing.
Online communities can act as a repository of relevant and helpful information related to various chronic diseases. These platforms often feature articles, videos, webinars, and other educational resources that can assist individuals in understanding their condition better. Expert opinions, latest research findings, and advice on various aspects of disease management including medication, diet, exercise, and lifestyle changes can be found.
Furthermore, these online platforms often host professionals from the healthcare field, like doctors, nurses or therapists, who provide advice and answer queries. Such interactions not only help in clarifying doubts but also empower patients with knowledge, enabling them to make informed decisions regarding their health.
Virtual reality (VR) and augmented reality (AR) technologies are also being incorporated into these platforms. These technologies can significantly enhance the learning and interactive experiences of members. For instance, VR can be used to illustrate the impact of a particular disease on the body, making the information more comprehensible.
Therefore, the potential of virtual support groups in enhancing the knowledge and skills of individuals to manage their chronic illnesses should not be underestimated. They serve as a valuable tool in the chronic disease management toolkit, complementing traditional healthcare services.
As we look towards the future, the role of virtual support groups in chronic illness management is set to become more prominent. Advancements in technology are expected to further enhance the effectiveness and reach of these platforms.
With the development of AI technologies, personalized support and advice can become a reality. AI can analyze individual health data to provide tailored advice, reminders for medication or appointments, and alerts for potential health risks. Integrating wearable technology can further enhance this personalization, providing real-time health data for analysis.
The use of VR and AR technologies can also be expanded. Apart from enhancing learning experiences, they can also be used for therapeutic purposes. For instance, VR can simulate relaxing environments for stress management, a crucial aspect of chronic illness management.
Additionally, the global reach of these platforms can be expanded to include more diverse groups, thereby facilitating the sharing of a wider range of experiences and knowledge. Ensuring accessibility for individuals with different levels of digital literacy is also an important aspect to be addressed.
In conclusion, the future of virtual support groups in chronic illness management looks promising. With continued advancements in technology and greater recognition of their value, these platforms can become an indispensable part of chronic illness management, providing emotional support, practical advice, and a sense of community for those living with chronic diseases. | medical |
https://mdmh-fayetteville.com/rapid-testing-available-to-some-in-northwest-arkansas/ | 2023-09-28T16:47:42 | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510427.16/warc/CC-MAIN-20230928162907-20230928192907-00166.warc.gz | 0.908972 | 1,163 | CC-MAIN-2023-40 | webtext-fineweb__CC-MAIN-2023-40__0__69306714 | en | FAYETTEVILLE, Ark. — Community Clinic, which has four coronavirus screening sites in Northwest Arkansas, now has the technology to have test results in 15 minutes, according to a news release from the clinic.
“Because of extremely limited supply for this innovative test, priority is given to frontline healthcare workers to ensure they can continue to do their essential work in the face of possible exposure,” according to the news release.
Coronavirus screening sites
• Walmart/Quest testing site: 9 a.m.-4 p.m., 702 S.W. Eighth St. in Bentonville
• UAMS digital screening: www.uamshealth.com/healthnow
• UAMS hotline: (800) 632-4502
• Washington Regional hotline: 8 a.m.-5 p.m. Monday through Friday and 8 a.m.-3 p.m. Saturday and Sunday, (479) 463-2055
• Washington Regional Coronavirus Screening Center: 10 a.m.-6 p.m. Monday through Friday and 10 a.m.-2 p.m. Saturday and Sunday, 3318 N. North Hills Blvd. in Fayetteville
• Washington Regional Family Clinic drive-through screening clinic: 9 a.m.-1 p.m. Monday through Friday, 146 Passion Play Road, Suite A in Eureka Springs
• Washington Regional screening clinic: 10 a.m.-6 p.m. Monday through Friday, 10 a.m.-2 p.m. Saturday and Sunday, 3318 N. North Hills Blvd in Fayetteville
• Arkansas Children’s Hospital hotline for child health: (800) 743-3616
• Community Clinic Siloam Springs Medical: 8 a.m.-5 p.m. Monday through Friday, 500 S. Mount Olive St., No. 200 in Siloam Springs
• Community Clinic Rogers Medical: 8 a.m.-5 p.m. Monday through Friday, 1233 W. Poplar St. in Rogers
• Community Clinic Fayetteville Medical: 8 a.m.-5 p.m. Monday through Friday, 162 W. Martin Luther King Jr. Blvd., Suite 13-14 in Fayetteville
• Community Clinic Springdale Medical and Pediatrics: 8 a.m.-5 p.m. Monday through Friday, 614 E. Emma Ave., Suite 300 in Springdale
• Medical Associates of Northwest Arkansas Family Medicine South: 7 a.m.-5 p.m. Monday through Friday, 2523 E. Huntsville Road in Fayetteville
• Medical Associates of Northwest Arkansas online screening: mana.md/covid-19-screening/
• Medical Associates of Northwest Arkansas fever hotline: (479) 435-2500
• MedExpress Urgent Care: 8 a.m.-8 p.m., 1160 S. 40th St. in Springdale. Patients must call (479) 750-2971 to make an appointment.
• Northwest Medical Center: 601 S.W. Regional Airport Blvd. in Bentonville. Patients may call (479) 306-7507.
• Northwest Medical Center: 2158 Butterfield Coach Road, Suite 100 in Springdale. Patients may call (479) 306-7507.
• Mercy Coronavirus Evaluation Site: Mercy Convenient Care, 3101 S.E. 14th St. in Bentonville. Patients must call (479) 717-7585 beforehand to make an appointment to be screened.
• Veterans enrolled in Veterans Affairs health care may call (800) 691-8387
Community Clinic will continue to collect specimens from most people to be tested at commercial labs. Most test results are available within a day or two, according to Abbie Luzius, community development manager for the clinic.
Gov. Asa Hutchinson over the past few days urged any Arkansan with covid-19 symptoms to seek testing. Symptoms include coughing, fever and shortness of breath, chills, repeated shaking with chills, muscle pain, headache, sore throat and loss of taste or smell, according to a revised list from the federal Centers for Disease Control and Prevention.
Community Clinic tested 547 people from March 30 through Thursday, Luzius said.
Community Clinic has closed its screening clinic at Elmdale Elementary School in Springdale to increase staff at its office on Emma Avenue, according to the release.
Several clinics in Northwest Arkansas are screening people for coronavirus. Most are generally collecting specimens via mouth or nasal swabs and sending them to be tested at commercial labs or the Arkansas Department of Health.
Mercy Health System collected specimens to be tested from 1,113 people from March 20 through Thursday, according to Jennifer Cook, spokeswoman. People who suspect they have covid-19 must call Mercy’s call center and be screened and make an appointment before going to Mercy’s evaluation site in Bentonville.
Washington Regional Medical System saw 2,110 people at its screening and respiratory illness clinics in Fayetteville from March 16 through Thursday, according to Cynthia Crowder, spokeswoman.
Crowder said most test results take a day or two. Washington Regional doesn’t report how many people it tests for covid-19. The medical system’s coronavirus screening hotline received 11,475 calls from March 16 through Thursday, according to Crowder.
Washington County had 62 covid-19 cases and two deaths as of 5:15 p.m. Friday, according to the Arkansas Department of Health. Benton County had 71 cases. | medical |
http://kellylarsondds.com.edit.officite.com/ | 2016-09-26T12:05:34 | s3://commoncrawl/crawl-data/CC-MAIN-2016-40/segments/1474738660760.0/warc/CC-MAIN-20160924173740-00050-ip-10-143-35-109.ec2.internal.warc.gz | 0.923629 | 649 | CC-MAIN-2016-40 | webtext-fineweb__CC-MAIN-2016-40__0__37028829 | en | Specializing in Healthy Smiles
Dentists in Prescott Valley - Dr. Kelly Larson and Dr. Seth Larson
Welcome to the Prescott Valley Arizona office of Dr. Kelly Larson and Dr. Seth Larson! We specialize in providing the highest quality dental care in a friendly environment. Our staff will make you feel like family, while both Dr. Kelly and Dr. Seth do everything possible to help their patients to be happy and comfortable. Anytime you receive treatment in our office, you can rest assured that only the best dental materials and most advanced techniques will be used to provide you with a healthy smile you can be proud of.
Our Dental Services
Our doctors provide the complete range of only the best in modern dental treatment, including cosmetics, periodontics, oral surgery, a wide range of implant therapies and full mouth restorations. We provide complimentary consultions for patients who wish to be fully educated about their treatment options and get the professional advice they need to make the best decision for their oral health.
We are happy to provide conscious sedation for patients who struggle with dental anxiety. Laughing gas can also be used to increase your level of comfort during treatment without being overly sedated. Our doctors and staff are fully committed to making your visits as comfortable as possible.
We proudly offer the latest in laser therapy. Using a laser to assist with regular cleanings is a painless and inexpensive way to help arrest the progression of gum disease and improve your oral health. Laser therapy can even be used during deep cleanings to speed healing and decrease post-operative discomfort. We have seen fantastic results that have left our patients feeling happier and heathier. Ask about our laser treatment options today!
Dental implants are the current pinnacle of dental technology. They can be used to replace a single missing tooth or an entire mouth of missing teeth. We are excited to offer the latest in full mouth implant restorations, including CONUS® and All on 4®. Same day teeth with implants can be a reality for you! In addition to offering both of those excellent treatment options, we are able to provide less costly alternatives in the form of dentures that can be anchored to either traditional implants or even miniature implants. For more information select the implant tab above, or visit our implant specific website by clicking here. Call today for a complimentary implant consultation.
You can have an all new smile with cosmetic dentistry. We use only the best techniques to help you achieve the smile you have always dreamed of. Options can include cosmetic crowns, porcelain veneers, chariside veneers, bleaching and more! Visit our Cosmetic Smile Gallery to view photograhs of some of our many happy patients. Please feel free to contact our office today for a complimentary cosmetic consultation.
Community, Experience and Compassion
Our practice has been located in Prescott Valley for over 20 years and has always been dedicated to providing the best, high quality dental care while maintaining patient comfort. Both Dr. Kelly and Dr. Seth love to help fearful patients complete their care stress free. Explore our website to find information on the many services we provide and then come into the office to experience the Larson Dental difference! | medical |
https://musictogetherofbelmont.com/health-policy.html | 2021-02-25T02:26:58 | s3://commoncrawl/crawl-data/CC-MAIN-2021-10/segments/1614178350706.6/warc/CC-MAIN-20210225012257-20210225042257-00519.warc.gz | 0.944518 | 190 | CC-MAIN-2021-10 | webtext-fineweb__CC-MAIN-2021-10__0__93288761 | en | We are committed to providing a safe environment for everyone in our classes. Please follow these recommendations in order to keep everyone healthy:
- Please keep children at home if they do not feel well and wait until all symptoms of illness vanish or the child is cleared by his/her pediatrician to return to class after being sick.
- Please take advantage of our generous Make up policy.
- Please wash your hands and your children’s hands before class, after coughing or sneezing, and after diapering, or use hand sanitizer provided in class.
- Please teach preschoolers to sneeze into their elbow and throw away tissues after a single use, rewashing hands.
- Please separate ALL instruments that have been mouthed into a provided bin, regardless of whether your child has a cold or not, so we can clean them after class.
Thank you for being a part of a caring community! | medical |
http://grimoakpress.com/about/ | 2017-12-14T02:38:41 | s3://commoncrawl/crawl-data/CC-MAIN-2017-51/segments/1512948537139.36/warc/CC-MAIN-20171214020144-20171214040144-00756.warc.gz | 0.975383 | 343 | CC-MAIN-2017-51 | webtext-fineweb__CC-MAIN-2017-51__0__223725288 | en | Welcome to Grim Oak Press, a tiny publishing press with a big dream.
In 2011, I was diagnosed with Stage III non-Hodgkin’s lymphoma in both sides of my neck, chest and spleen. While a cancer diagnosis and its treatment is not an ideal situation, I also did not have health insurance.
I had a lot to deal with in a short amount of time. Tests. Surgery to remove a lymph node to diagnose the cancer properly. Surgery to install a port-a-cath into the left side of my chest to receive the chemotherapy—and make me bionic, of course! Six months of treatment to kill what was trying to kill me. And eventually the port-a-cath removal.
I received great care and have slowly recovered. That said, while I am currently in remission, I had accrued a massive medical debt. To combat that, many of my SF&F writer friends contributed short stories that became the bestselling anthology Unfettered. It, coupled with sales from my debut novel The Dark Thorn, paid off more than $200,000 in medical bills. I am very fortunate to have such friends. Without them, I would have had to declare bankruptcy and become just another statistic.
I am in a unique situation now. I am paying forward the aid I received. A percentage of sales from every book Grim Oak Press publishes goes to a charitable cause. The author decides where. In this way, Grim Oak Press tries to make the world a better place.
Thank all of the writers who have contributed. And thank you to all SF&F fans who purchase these books. You will forever be in my debt! | medical |
https://en.docrobo.com/articledetail/369.html | 2024-03-03T12:01:47 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947476374.40/warc/CC-MAIN-20240303111005-20240303141005-00586.warc.gz | 0.882561 | 246 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__203007816 | en | Recently, ROBO Medical TARZAN Jie Hang intelligent lower limb rehabilitation robot expert review meeting was successfully held, this meeting invited Li Jianan, Bai Yulong, Wan Xiaochun, Jin Rongjiang, Wang Yulong, Luo Lun, Ao Lijuan, Chen Wenhua, Li Yongqiang and other well-known experts in the field of rehabilitation in China.
The experts listened to the research and development background, product introduction and clinical trial results of TARZAN's intelligent lower limb rehabilitation robot, and evaluated the rehabilitation effect of TARZAN. Through consultation and observation, on-site fitting, the expert group felt the lightness and home-friendliness of TARZAN, and based on clinical experience, put forward targeted suggestions for TARZAN in product upgrading and clinical application.
The successful holding of the expert review meeting has provided a more solid foundation for the future development and clinical application of TARZAN smart lower limb rehabilitation robot. ROBO Medical will adhere to the corporate mission of "empowering science and technology, making medical care boundless", and provide more convenient and efficient rehabilitation robots for the benefit of more doctors and patients! | medical |
https://www.bfdentalsociety.org/news-details/2023/10/25/shape-workforce-policy-participate-in-the-health-workforce-sentinel-network | 2024-03-02T02:26:31 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947475727.3/warc/CC-MAIN-20240302020802-20240302050802-00645.warc.gz | 0.88207 | 445 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__75355831 | en | Your voice matters in shaping healthcare in Washington. Take the Health Workforce Sentinel Network survey by November 10.
Your voice matters in shaping healthcare in Washington. By completing a brief survey for the Health Workforce Sentinel Network now, you will improve understanding of Washington’s health workforce needs.
Why your participation matters:
- Drive meaningful change. Previous findings from the Sentinel Network have helped state legislators, educators and other healthcare organizations create new workforce strategies.
- Inform statewide planning. For example, past findings played a pivotal role in improving behavioral health planning and workforce policies in Washington.
- Gain valuable insights. Respondents can view findings on the Sentinel Network dashboard to learn new strategies for responding to health workforce challenges.
Take approximately 15 minutes to respond to the questions today. Your ongoing participation is crucial to address evolving state needs. Survey results will be shared with key policymakers and other stakeholders to inform the policy development and funding decisions impacting our vital health workforce.
Take the Survey
Your feedback is critical and confidential. Please be assured that data you provide to the Sentinel Network will be kept confidential. Your organization’s data will be reported in aggregate form with data from similar organizations. Great care will be taken to ensure that no individual organization’s responses can be identified in reports.
Policymakers are paying attention to your input. The WA Health Workforce Sentinel Network is funded by the Legislature, and it is clear that policymakers are paying attention to this tool. For example, information provided by you helped the state craft regulatory changes to respond to the COVID-19 pandemic and invest in promising workforce pathways. As the pandemic continues, let policymakers know what workforce challenges you are facing now.
Questions? Email [email protected] or call (206) 543-9797.
Washington’s Sentinel Network is a collaboration of the state’s Workforce Board and the University of Washington’s Center for Health Workforce Studies and a program of Washington’s Health Workforce Council. Funding to initiate the Sentinel Network came from the Healthier Washington initiative, with ongoing support from Governor Inslee’s office and the Washington Legislature. | medical |
http://lincolnveterinaryclinic.vetstreet.com/care_guide.html | 2019-10-16T12:40:28 | s3://commoncrawl/crawl-data/CC-MAIN-2019-43/segments/1570986668569.22/warc/CC-MAIN-20191016113040-20191016140540-00192.warc.gz | 0.926149 | 730 | CC-MAIN-2019-43 | webtext-fineweb__CC-MAIN-2019-43__0__184237606 | en | Featured Care Guides
Heartworm disease is a serious and potentially fatal condition that affects dogs, cats, and up to 30 other species of animals. It is caused by parasitic worms (heartworms) living in the major blood vessels of the lungs and, occasionally, in the heart. These worms are transmitted (as microscopic larvae) through the bite of an infected mosquito. The scientific name for the heartworm parasite is Dirofilaria immitis.
A variety of cat litters are available commercially, including litters made of clay, plastic, wheat, sawdust, newspaper pellets, and corn cobs. The choice depends on what matters most to you and your cat. You may have to try a few to see what you and your cat like. Most cats prefer unscented, scoopable litter because of its sandlike texture. Many owners prefer scoopable litters because they control odors and absorb liquid (clump) well, making it easy for owners to scoop out urine “balls.” This leaves the remaining litter dry and odor free.
When deciding what to feed your new puppy, make sure you get reliable, professional veterinary advice.
Cats are known for grooming themselves, but a little help is never wasted. Regular brushing can help keep your cat’s skin and haircoat healthy and can be another way to strengthen the relationship between you and your pet.
All Care Guides
Asparagus fern (also called emerald feather, emerald fern, sprengeri fern, plumosa fern, and lace fern) is toxic to dogs and cats. The toxic agent in this plant is sapogenin—a steroid found in a variety of plants. If a dog or cat ingests the berries of this plant, vomiting, diarrhea, and/or abdominal pain can occur. Allergic dermatitis (skin inflammation) can occur if an animal is repeatedly exposed to this plant.Read More
Here are tips to manage this condition and minimize your dog’s discomfort.Read More
Fleas are blood-feeding parasites that can infest many species of birds and mammals. Although fleas on dogs and cats don’t infest people, fleas may bite people if an area is heavily infested. Flea infestation is one of the most common medical problems veterinarians see, and pets suffer greatly from this condition. Flea bites can trigger severe allergic reactions in some pets. The intense itching caused by flea infestation causes pets to scratch and bite themselves. This can lead to skin wounds, skin infections, and general misery for your pet. Even if your pet is not allergic to flea bites, fleas can transmit serious diseases, such as bartonellosis (the bacteria that causes “cat scratch disease” in people), and other parasites, like tapeworms.Read More
Glucocorticoids (primarily cortisol) and mineralocorticoids are two important types of hormones produced by the body’s adrenal glands. Glucocorticoids and mineralocorticoids help regulate numerous complex processes in the body and participate in critically important functions.Read More
A radiograph (sometimes called an x-ray) is a type of photograph that reveals the body’s internal organs. The procedure for obtaining a radiograph is called radiography. Radiography is a very useful diagnostic tool for veterinarians because it can help obtain information about almost any organ in the body, including the heart, lungs, and abdominal organs, as well as the bones.Read More | medical |
https://victorioushosting.com/celebrating-national-blood-donor-month-saving-lives-one-pint-at-a-time/ | 2023-12-11T12:50:57 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679511159.96/warc/CC-MAIN-20231211112008-20231211142008-00294.warc.gz | 0.917549 | 778 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__280196269 | en | January is not just the month for making New Year’s resolutions; it’s also the month dedicated to celebrating National Blood Donor Month. This annual observance is a vital reminder of blood donors’ critical role in saving lives and maintaining a steady blood supply. As we kick off the year, let’s delve into the significance of National Blood Donor Month and explore why donating blood is a noble act that deserves recognition and appreciation.
You might wonder why January honors blood donors. The decision was not arbitrary. Winter is often challenging for blood banks and hospitals to maintain an adequate blood supply. Inclement weather, flu outbreaks, and holiday travel can lead to a decrease in blood donations. By designating January as National Blood Donor Month, organizations aim to encourage more people to donate during this critical time and address the potential shortage.
The Need for Blood
Blood is a precious resource that cannot be manufactured or synthesized. It plays a vital role in medical treatments, surgeries, trauma care, and managing various medical conditions. Your single donation not only saves one person, but it’s possible to save up to three. The demand for blood is constant, making regular donations a necessity.
National Blood Donor Month Goals
Raise Awareness: One of the primary goals of National Blood Donor Month is to raise awareness about the constant need for blood donations. Many people need to be made aware of their crucial role in saving lives by giving blood.
Express Gratitude: This month is also an opportunity to express gratitude to the dedicated blood donors who regularly roll up their sleeves to help others. Their selflessness is a testament to the power of human kindness.
Recruit New Donors: Encouraging new donors is vital for maintaining a stable blood supply. National Blood Donor Month campaigns often focus on inspiring individuals who have never donated blood before to try it.
Organize Blood Drives: Blood banks and healthcare organizations often collaborate to host blood drives throughout January. These events make it convenient for people to donate and contribute to the cause.
The Impact of Blood Donation
Donating blood has a profound impact on both donors and recipients. Here’s how:
Lifesaving: Blood donations are a lifeline for patients undergoing surgeries, cancer treatments, trauma care, and more. For many, it’s the difference between life and death.
Community Unity: Blood donation brings communities together. It’s a powerful way for individuals to contribute to the well-being of their neighbors and loved ones.
Health Benefits: Donating blood can also benefit the donor. It helps maintain healthy iron levels and reduces the risk of certain diseases.
Emotional Satisfaction: A unique sense of satisfaction comes with knowing you’ve played a role in saving lives. Many donors find the act of giving profoundly fulfilling.
How You Can Get Involved
Donate Blood: Donating blood is the most direct way to participate in National Blood Donor Month. Check with your local blood bank or healthcare provider for a donation center or blood drive near you.
Spread the Word: Raise National Blood Donor Month awareness on social media. Share your donation experiences, or if you know anyone who needed blood, highlight them if they want to share.
Volunteer: If you can’t donate blood for any reason, consider volunteering at a local blood drive or donation center. Your support is invaluable.
National Blood Donor Month is a reminder of the incredible impact that everyday individuals can have on the lives of those in need. By donating blood, spreading awareness, and expressing gratitude, we can make January a month of hope, compassion, and lifesaving contributions. So, this year, let’s resolve to give the gift of life and celebrate the heroes who make it all possible. | medical |
http://janotec.typepad.com/terrace/2006/09/coma_case_raise.html | 2017-04-24T13:17:30 | s3://commoncrawl/crawl-data/CC-MAIN-2017-17/segments/1492917119361.6/warc/CC-MAIN-20170423031159-00291-ip-10-145-167-34.ec2.internal.warc.gz | 0.958273 | 219 | CC-MAIN-2017-17 | webtext-fineweb__CC-MAIN-2017-17__0__25680067 | en | I like this little quote from the article the best:
Dr. James Bernat, a neurologist at Dartmouth medical school in New Hampshire and a fellow of the American Academy of Neurology, said the study showed it is possible to make a mistake in diagnosing a patient as unconscious.
"What we don't know is how often you see this discrepancy between the physical exam findings and fMRI findings," Bernat said. "Is this one case in 1,000? Is it 1 in 10?"
Some patients do recover after being in vegetative states for months, Bernat said. But this is difficult to predict.
"This is an important case because it shows us the limitations of the physical exam when we assess awareness at the bedside," Bernat said. "We can't get into the mind of another person and experience what they experience."
Of course, everyone is quick to point out that this has nothing whatsoever to do with Terry Schiavo's case.
Because if it did, then there would be another case, n'est-ce pas? | medical |
https://tw.stock.yahoo.com/news/alkermes-announces-recipients-2022-alkermes-183500822.html | 2024-04-20T14:00:23 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296817650.14/warc/CC-MAIN-20240420122043-20240420152043-00012.warc.gz | 0.929897 | 1,731 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__111481606 | en | DUBLIN, IRELAND / ACCESSWIRE / November 7, 2022 / - Alkermes plc (Nasdaq:ALKS) announced the 2022 recipients of the Alkermes Inspiration Grants® program. Grants were awarded to nine nonprofit organizations working to address the needs of people living with alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and cancer. The selected programs also have a focus on addressing unmet needs in historically under-resourced or underrepresented communities with longstanding and widespread health disparities.
"This year's Alkermes Inspiration Grants recipients inspire us with their innovative approaches to providing critical support for people living with addiction, serious mental illness or cancer, as well as their caregivers and family members. These organizations have the potential to positively impact people across the U.S. and offer an opportunity to engage diverse communities in new ways," said Richard Pops, Chief Executive Officer of Alkermes.
Nearly 250 applications were submitted for this highly competitive program. Submissions were evaluated based on a set of criteria outlined in the request for proposals, including clearly defined needs, objectives, activity format, mode of delivery and intended audience, and relevance to historically under-resourced or underrepresented communities. Grant recipients were selected by a committee that included senior leaders from Alkermes and individuals from outside the organization chosen to represent the perspectives of people with lived experience, caregivers and patient advocates.
"Alkermes' desire to support high-impact programs that can help those affected by addiction, cancer and serious mental illness came through clearly throughout the review process. I was impressed with the purposeful and collaborative effort, and the particular focus on supporting underserved communities and regions across the country," commented committee member Sharon Slade, Chief Marketing Officer, Cancer Research Institute.
Since 2016, the Alkermes Inspiration Grants program has awarded more than $4.5 million in funding to innovative programs that support the needs of those impacted by serious diseases in our areas of focus. For more information on the Alkermes Inspiration Grants program, please visit https://www.alkermes.com/responsibility.
2022 Grant Recipient Organizations and Programs:
The American Psychiatric Association Foundation's Building Bridges to Care: APAF Mental Health and Faith Community Partnership aims to foster dialogue to improve the understanding of mental health and substance use disorders, reduce stigma and increase connections to care with local community organizations, including faith-based organizations. The group will develop and disseminate culturally appropriate mental health information and resources for people with mental health and substance use disorders, including schizophrenia and bipolar disorder and/or caregivers for people living with these illnesses.
Community Anti-Drug Coalitions of America (CADCA) will create an alcohol use disorder (AUD) awareness video and fact sheet to further support CADCA's training of local grassroots groups, known as community coalitions, with the goal of developing effective community problem-solving strategies related to substance use disorders. Groups are taught how to assess their local alcohol, tobacco and other drug-related problems and develop a comprehensive plan to address them. The video and fact sheet will be used to increase awareness and reduce stigma of AUD and seeking treatment.
Depression and Bipolar Support Alliance's (DBSA) Addressing Mental Health Disparities Through Peer Support program will train Asian American/Pacific Islander, Black and rural peers with lived experience as support group facilitators and create 10 peer-led support groups. The goal is for participants to address and overcome systemic barriers, increase their access to mental health support and achieve positive mental health outcomes along their recovery journeys.
Foundation for Women's Cancer's (FWC) Move The Message campaign is designed to motivate high-risk and historically marginalized communities to take preventive action by increasing awareness of gynecologic cancers through dissemination of vital FWC resources. Gynecological cancer mortality rates are increasing among women of color and rural women, with late-stage diagnoses more prevalent due to lack of education and awareness. FWC will take its message directly to communities across the country to drive awareness and enhance education and support of early diagnoses by motivating people to help #MoveTheMessage.
The National Association for Children of Addiction's (NACoA) Children Deserve Recovery, Too! program seeks to deliver NACoA's Children Program Kit training on-demand via a Learning Management System to 40 community-based youth-serving nonprofits in historically under-resourced and underrepresented communities with high rates of alcohol or opioid use disorder. Children living with a parent or caregiver who has alcohol or opioid use disorder are at high risk for experiencing adverse childhood experiences (ACEs), making them vulnerable to lifelong negative mental and physical health consequences. Early prevention and intervention are key for addressing this systemic issue, and this program will provide proven, trauma-sensitive, culturally informed educational support programs to mitigate the impact of ACEs.
Ovarcome's Lifecycle of OVARCOMING program seeks to eradicate disparities in equity of care and information to Ovarcomers that are in an underrepresented part of the population. Ovarcome will educate, inform, engage and empower ovarian cancer survivors, caregivers, friends, family members and the general population with information on screening, genetics, detection, diagnosis, and treatment; a book of inspiration with real life stories for newly diagnosed patients; a video and resource packet to make Ovarcomers feel cared for; and a Clinical Trials Finder in both English and Spanish, among other resources. This information will help people take ownership of their treatment process and the journey of OVARCOMING.
Parents of Addicted Loved Ones' Healing Families of Substance Use Disorder in the Nation's Largest Cities program will start free weekly meeting groups utilizing Parents of Addicted Loved Ones' evidence-based education in the nation's 15 largest cities. The lessons used in the meetings will give parents whose adult children suffer from substance use disorder (SUD) the tools needed to encourage their loved one's recovery and provide peer-to-peer support to face the challenges of SUD.
Sound Mind Live's "Released" Mental Health Docuseries on bipolar disorder will be a five-part docuseries that will take us inside the lives and work of five influential musicians living with bipolar disorder. Each episode will focus on one artist living with bipolar disorder and how their journey with the condition and making music helped them break free from stigma to find support, healing and, ultimately, themselves to share their creations with the world. This will further the work Sound Mind Live does to bring together a coalition of mental health and music organizations with musicians and music lovers to build a supportive community and open dialogue around mental illness.
Young People in Recovery's (YPR) Native American Youth Substance Use Disorder Recovery Support Services Pilot will be a community-based chapter and redesign of one of their existing life-skills curriculum programs to be linguistically and culturally appropriate for Native American youths who struggle with substance misuse or who are in recovery from substance use disorder. YPR will partner with one tribe to launch a new chapter to serve tribal constituents under age 30. The program will be staffed by Native Americans and create a youth advisory board to inform the program with the values, language, and traditions of the specific tribe.
About Alkermes plc
Alkermes plc is a fully-integrated, global biopharmaceutical company developing innovative medicines in the fields of neuroscience and oncology. The company has a portfolio of proprietary commercial products focused on alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder, and a pipeline of product candidates in development for neurological disorders and cancer. Headquartered in Dublin, Ireland, Alkermes plc has a research and development center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. For more information, please visit Alkermes' website at www.alkermes.com.
ALKERMES INSPIRATION GRANTS® is a registered service mark of Alkermes, Inc.
For Investors: Sandra Coombs, +1 781 609 6377
For Media: Katie Joyce, +1 781 249 8927
View source version on accesswire.com: | medical |
https://www.accesshealthpros.com/join/advanced-practice-provider-opportunity-in-indianapolis-area/ | 2019-10-19T17:03:44 | s3://commoncrawl/crawl-data/CC-MAIN-2019-43/segments/1570986697439.41/warc/CC-MAIN-20191019164943-20191019192443-00273.warc.gz | 0.950613 | 129 | CC-MAIN-2019-43 | webtext-fineweb__CC-MAIN-2019-43__0__214682197 | en | Our current need for placement includes the north Indianapolis area with opportunity for other locations as we grow. Access Health Professionals is physician-owned and our doctors remain active in the practice and continue to lead and manage our providers. Our focus is providing excellence in patient care and we pride ourselves on collaboration with other specialties and referring providers.
At Access Health Professionals, we offer an exceptional work environment with excellent work-life balance. We offer a competitive compensation package. Qualified candidates are kindly asked to submit their CV and salary expectations to Tara Lutes, Manager of Operations/General Counsel at [email protected]. | medical |
https://evergreen.ie/blogs/beauty-fitness/what-are-the-health-benefits-of-collagen | 2023-03-25T20:27:19 | s3://commoncrawl/crawl-data/CC-MAIN-2023-14/segments/1679296945372.38/warc/CC-MAIN-20230325191930-20230325221930-00275.warc.gz | 0.945083 | 873 | CC-MAIN-2023-14 | webtext-fineweb__CC-MAIN-2023-14__0__47430729 | en | Collagen supplements are a hot topic right now, and for good reason. So what is collagen? And of course, what are the health benefits of collagen? Collagen is an amazing nutrient which helps to optimise overall health and provide essential amino acids responsible for healthy joints and skin elasticity.
It's a bit of a hero product in beauty circles at the moment because of its power to help fight ageing. People are turning to it to help improve skin elasticity and reduce the appearance of wrinkles.
But not all collagen supplements are created equal. Collagen can be sourced from cows (bovine), fish (marine) or even chicken. We talk you through the types available, which one is best as well as the many health benefits of collagen.
What is Collagen?
Collagen is the most abundant protein found in the body. There are 28 different types of collagen, with type I, II, and III being the most common. Together, these three types of collagen are responsible for the health of your skin, hair, bones, teeth, tendons, ligaments and organs (types I), your cartilage (type II), and your muscles and blood vessels (type III).
What are the health benefits of collagen?
Collagen is big news in the beauty world right now but why? Just what are the health benefits of collagen? More and more people are now supplementing with collagen supplement powders and tablets because of the many associated health benefits, such as improved skin health (in particular, better elasticity and a reduction in wrinkles), thicker hair, longer nails and stronger bones. It has been shown to support muscle repair too.
It's important that you are obtaining enough dietary collagen through your diet to support your overall health, especially to contribute towards healthy ageing. As we age our natural collagen levels decline, starting in our 20s. Supplementing with collagen peptides, can help to keep your collagen levels at a healthy level.
Where is Collagen found?
Collagen peptides are made from cattle (bovine), pigs (porcine), chicken, or fish (marine). Each type has their own unique health advantages. The collagen comes from the skin, scales (fish) or bones of the animal depending on what type of collagen you have decided to use.
The Main Types Of Collagen Supplements
Marine collagen is a dietary supplement made by extracting collagen from the bones, skin or scales of fish. It is comprised of mostly type I collagen - the main collagen found in the human body. Marine collagen is similar in size to human collagen. This means it can be more bioavailable and easy to absorb into key areas of the body such as skin, hair, bones, teeth, tendons, ligaments and organs.
It has a smaller molecular structure which some believe can be easier to digest. This may be beneficial to those who may be taking collagen for digestive associated issues for example leaky gut.
Bovine collagen is made by extracting the collagen from the hide of the cattle and is most commonly found in a powdered form. When searching for a bovine collagen, we would recommend sourcing a good quality product where the cattle have been grass-fed and have not exposed to antibiotics, hormones or pesticides. This is important!
The main difference between marine and bovine collagen is the types of collagen they contain; Bovine collagen is mainly comprised of type I and type III collagen which are both abundant in the human body. Whereas type I is more prevalent in marine collagen.
How to Use Collagen:
So we've looked at what is collagen and the health benefits of collagen. Now on to how to use it! It is available in both tablet form and powders, depending on the type and brand. Collagen powders are very easy to add into the diet. Try adding it to hot or cold drinks, soups or stews. Check out our range of collagen supplements available in store and online.
Please note, this blog is for informational purposes only and should not replace medical advice.
It’s always best to consult your doctor before taking any new supplements, treatments or remedies if you are pregnant, breastfeeding or on medication.
Checked and updated: 22 August 2021 | medical |
https://enterprisecommunity.org/blog/enterprise-community-partners-and-new-york-city-health-department-launch-innovative-medicaid | 2023-12-11T12:05:09 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679511159.96/warc/CC-MAIN-20231211112008-20231211142008-00211.warc.gz | 0.938386 | 842 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__118813913 | en | The initiative seeks to drastically reduce asthma hospitalizations for low-income children and demonstrate the cost savings to healthcare of investment in housing improvements.
In New York City, households with cockroaches are 50 percent more likely to have someone diagnosed with asthma compared to the general population, and those with mice are twice as likely. 1 While local law requires many New York City property owners to carry out pest control in the homes of people with asthma, landlords ultimately have little incentive to do so comprehensively.
Meanwhile, medical insurers have a strong financial incentive to mitigate asthma hospitalizations, but they have rarely paid for housing-related interventions like pest management because of an understandable reluctance to invest in an unfamiliar sector.
To bridge this disconnect and to demonstrate that healthcare investment in housing improvements can sustainably generate financial benefits to insurers, Enterprise and the New York City Department of Health and Mental Hygiene (DOHMH) launched a groundbreaking new initiative: the Medicaid Together Improving Asthma Program, in partnership with five Medicaid health plans and multiple New York City hospitals.
The program challenges the healthcare sector to invest in asthma-focused housing improvements, specifically Integrated Pest Management with Allergy Reduction (IPM-AR), which is expected to decrease asthma hospitalizations among low-income children.
Landlords are responsible for the home improvements of tenants, and both the healthcare sector and residents benefit from healthier housing environments. The Medicaid Together Improving Asthma Program acknowledges the benefit of healthy housing by creating a platform for the health insurance sector to invest in the reduction of asthma triggers without removing full responsibility from landlords. Five Medicaid managed care organizations (MCOs) – Empire Blue Cross Blue Shield HealthPlus, EmblemHealth, Fidelis Care, Healthfirst and MetroPlusHealth – are participating in the program and together insure 87 percent of the children on Medicaid in New York City. 2
A system that benefits patients and managed care organizations
IPM-AR is a proven intervention that removes existing pest allergens from the home and improves the home’s structural and sanitary conditions to deny pests food, water, harborage and movement, decreasing asthma symptoms among children without the side effects of traditional pest control. By addressing the underlying causes of asthma exacerbation, IPM-AR has the potential to generate healthier New Yorkers with fewer asthma exacerbations and health care cost savings for insurers and healthcare providers, who are at full risk for asthma-related healthcare costs.
While there is public health consensus that IPM-AR is likely to yield a financial return, we are committing a $1.2 million guarantee fund to mitigate the perceived risk of using healthcare dollars to pay for a treatment that is not established as an insurance benefit, and to make this treatment available across health plans. This funding serves as a profitability guarantee for the five MCOs participating in the Medicaid Together program. If insurers don’t realize the reductions in hospital use projected to result from IPM-AR interventions, they will be eligible to recoup all or part of their costs through the guarantee fund.
The program was launched to demonstrate that by investing in IPM-AR services, insurers will financially benefit through reductions in asthma hospitalizations. If successful, we expect that this kind of upstream housing intervention will be a model for future healthcare investments.
Another innovative component of the program involves the pooling of funding among five different private Medicaid insurers. All five organizations are funding the effort based on their respective share of members and a single centralized non-profit point of contact is coordinating the IPM services to individual households.
With the Affordable Care Act’s push towards payments that incentivize patient health outcomes over healthcare procedures, the healthcare sector has begun to look at investing in social determinants of health through direct interventions that lead to improved healthcare outcomes while lowering cost of care. The Medicaid Together Improving Asthma program supports this movement and incentivizes private investment by MCOs in the public good.
We thank the New York City Health Department for their partnership in this critical endeavor and we look forward to reporting on progress made in the program.
1 New York City Housing and Vacancy Survey (2002)
2New York State Medicaid managed care enrollment as of December 2021 | medical |
https://www.businesaffair.com/the-importance-of-regular-check-ups-at-your-local-medical-centre/ | 2024-04-19T02:50:02 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296817253.5/warc/CC-MAIN-20240419013002-20240419043002-00027.warc.gz | 0.934002 | 640 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__128507167 | en | In the hustle and bustle of daily life, it’s easy to neglect things that are important to us like health and skincare. We are so busy with our jobs and house chores that we tend to put off healthcare for a later time. Even though it is important to take care of daily routine tasks, it’s equally crucial to take some time out from your routine to get a health care check-up at your local medical center. It helps in diagnosis of any potential illness or disease that may pose a threat to your life.
In this guide, we’ll delve into the importance of these routine visits.
Early Detection of Health Issues
Regular check-ups at an urgent care clinic serves as a proactive measure in identifying health concerns before they become serious. Through screenings, tests, and discussions with your healthcare provider, potential problems can be spotted early. Early detection often leads to more effective treatment and improved outcomes.
Monitoring Chronic Conditions
If you have a chronic condition like diabetes, hypertension, or asthma, regular check-ups are crucial. They allow your healthcare provider to monitor your condition, adjust treatment plans as needed, and offer guidance on managing your health. Consistent monitoring can help prevent complications and maintain your quality of life.
Building a Relationship with Your Healthcare Provider
Continuity of care is essential in healthcare. By attending regular check-ups, you build a lasting relationship with your healthcare provider or medical director. They become familiar with your medical history, preferences, and unique health needs, ensuring personalized care.
Vaccinations and Preventive Care
Staying up-to-date with vaccinations and preventive care is a vital aspect of regular check-ups. Vaccinations protect you from contagious diseases, while preventive care, such as cancer screenings and cholesterol checks, can catch potential health threats early.
If you’re taking medications, your healthcare provider can review and adjust your prescriptions during check-ups. This ensures that your medications are working as intended and that you’re not experiencing any adverse side effects or interactions.
Your healthcare provider can offer valuable advice on maintaining a healthy lifestyle. From nutrition and exercise recommendations to stress management tips, these check-ups are an opportunity to discuss your overall well-being and make positive changes.
Mental Health Check-Ins
Mental health is as important as physical health. Regular check-ups provide an opportunity to discuss any mental health concerns, such as stress, anxiety, or depression. Your healthcare provider can offer support, referrals, or treatment options to address these issues.
Establishing a Health Baseline
Regular check-ups help establish a baseline for your health. Your healthcare provider records your vital signs, blood pressure, cholesterol levels, and more. These baseline measurements enable them to track changes over time and spot deviations that may require attention.
Peace of Mind
Knowing that you’re taking proactive steps to care for your health provides a sense of peace and confidence. Regular check-ups offer reassurance that you’re prioritizing your well-being and staying on top of any potential health issues. | medical |
https://www.carsonoptometrist.com/ | 2024-04-12T14:44:11 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296816024.45/warc/CC-MAIN-20240412132154-20240412162154-00157.warc.gz | 0.957708 | 249 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__39808952 | en | Welcome to Dr Kristen Lee OD where your vision and eye health are our primary concern. We look forward to meeting you and helping you with all of your optometric eyecare needs. We are located in Carson, CA, and have long been recognized as a leader in patient care. Since we started in 1985, our board-certified ophthalmologists and optometrists have offered the highest standards of quality and individualized attention in a relaxed, professional atmosphere.
We offer a full range of options to meet your eyecare needs. From advanced custom LASIK laser vision correction and cataract surgery to glasses to eye infections, contact lens fittings and routine eye tests, we can provide the treatment that is right for you. We stock a large selection of contact lenses as well as fashionable frames - including Prada, Rayban & Bebe - that are sure to suit your eyewear needs.
Please don't hesitate to contact us if you are concerned about your general eye health or are interested in LASIK screening, hard-to-fit contact lenses, or treatment for cataracts. Our optometry office is just a short drive from Torrance and Long Beach. We look forward to seeing you! | medical |
http://aitcnh.com/ | 2017-02-20T15:19:19 | s3://commoncrawl/crawl-data/CC-MAIN-2017-09/segments/1487501170569.99/warc/CC-MAIN-20170219104610-00238-ip-10-171-10-108.ec2.internal.warc.gz | 0.942611 | 252 | CC-MAIN-2017-09 | webtext-fineweb__CC-MAIN-2017-09__0__219479265 | en | Welcome to Advanced Injury Treatment Center
At Advanced Injury Treatment Center (AITC) we specialize in physical therapy and chiropractic care. We have been serving Bedford NH and the surrounding area for over 15 years.
Our caring, professional staff is dedicated to restoring your body’s optimal function. Advanced Injury Treatment Center (AITC) provides individualized treatment programs to relieve pain, increase function and help our clients move better.
Our goal is to provide a proactive and unique approach to physical wellness that emphasizes treating and conditioning the entire body rather than a particular injury.
We use evidence-based, movement-focused evaluation techniques and treatment tools with a consistent standard of care.
Advanced Injury Treatment Center (AITC) is privately owned and operated and, as an independent practice, we have the freedom to refer to any specialist agreed upon by you and our professional staff based on our clients’ preferences and medical needs.
We continuously work together as a team to keep our skills sharp and our philosophy in tune to the needs of our clients and the advances in client care.
Also available at our location are massage therapy with the licensed massage therapists of Therapy Designed For You and counseling with Susan MacDermott, licensed clinical mental health counselor. | medical |
http://niska.org/creativityProject.php | 2018-02-17T23:17:32 | s3://commoncrawl/crawl-data/CC-MAIN-2018-09/segments/1518891808539.63/warc/CC-MAIN-20180217224905-20180218004905-00559.warc.gz | 0.94295 | 193 | CC-MAIN-2018-09 | webtext-fineweb__CC-MAIN-2018-09__0__2333108 | en | Dr. Oliver Sacks on the therapeutic power of art: “The therapeutic power of art is temporary; it can liberate the patient only while the performance or creative act is occurring. Turning to creativity can activate the patient, allowing him to fight and sometimes conquer PD for years on end. But knowing that they can be liberated in this way, and in doing so, they can reclaim for a while their healthy selves. This area of creativity and the extraordinary power of art is ripe for exploration by the next generation of neuroscientists.” — Parkinson’s Post, Fall/Winter 2006, pg. 14
Dr. Oliver Sacks was Honorary Chairman of this Creativity and Parkinson’s initiative at the World Parkinson Congress in Washington DC. Dr.Sacks is Professor of Neurology and Psychiatry at Colombia University, he is a bestselling author and a Fellow of the American Academy of Arts and Letters and the American Academy of Arts and Sciences. | medical |
https://thestarsthatfall.wordpress.com/2017/01/10/buh-bye-hives/ | 2018-06-22T14:52:23 | s3://commoncrawl/crawl-data/CC-MAIN-2018-26/segments/1529267864546.30/warc/CC-MAIN-20180622143142-20180622163142-00161.warc.gz | 0.982427 | 556 | CC-MAIN-2018-26 | webtext-fineweb__CC-MAIN-2018-26__0__31798957 | en | I had my IUD removed last week. I was experiencing hives just about daily which would get worse when I was spotting or having my period. I needed to have it removed to find out if it was the cause or not. I’ve already had no issues with hives since it’s removal, but there have been other issues.
I’m still somewhat itchy, but I was informed that my hormones would need to normalize before that would go away. My body has to adjust without hormones and get back to some kind of baseline. A friend recommended chasteberry which I’ve taken previously. It helped get my body back to regularity after it was messed up from taking birth control pills.
Heavy menstrual bleeding is apparently normal after removal. I already have a blood disorder where my blood is thin and takes a long time to clot. Normal clotting time is between 5-7 minutes. I usually run 9-10 minutes. I have to take iron supplements and I get anemia and bruising quite easily. It has brought on a lot of fatigue and this feeling of being unwell (which is kind of weird because I feel so much better since having the IUD taken out). There isn’t much I can do except to continue taking my vitamins, eating better, and recognizing when my body needs to rest.
I made steak for dinner because I felt like I needed it. I’ve been trying to have salad and greens daily, but sometimes it isn’t enough. I can tell when my iron level is low because of the white spots on my nails. I can also tell when I cook my steak bloody instead of well done. I hate any red on my steak under normal circumstances, except when my iron is low. I paired it with homemade mac n cheese for my daughter and a big salad.
The next issue I’m not even sure what to do about. My joints hurt. A lot. I was diagnosed with a positive rheumatoid factor and fibromyalgia, but I learned to manage the muscular pain. This joint pain started the day after the IUD was removed. I have read a few posts of people complaining of joint pain after removal of their IUDs so I’m hoping that this is only temporary. I have done well with balancing out what my body can take and I have been proud of myself for it. I’m just really confused by the pain.
I’m not working out at this point. I’m just trying to work on my eating habits and will gradually increase what I need as I begin walking and working out again. Patience is the key. I will get there. | medical |
http://www.stressymummy.com/2013/02/private-consultants-in-london_22.html | 2013-05-18T09:18:58 | s3://commoncrawl/crawl-data/CC-MAIN-2013-20/segments/1368696382185/warc/CC-MAIN-20130516092622-00057-ip-10-60-113-184.ec2.internal.warc.gz | 0.968189 | 463 | CC-MAIN-2013-20 | webtext-fineweb__CC-MAIN-2013-20__0__135024742 | en | At NHS hospitals, a consultant will often only be seen if the case is particularly complex. Busy mother could take their children to private consultants in London for this and a number of other reasons.
Private consultants often have rapid access to complex diagnostic facilities, such as ultrasound, CT, MRI and X-rays. Drugs not offered by the NHS are available. Private consultants will frequently offer appointments outside of working hours. Consultations usually last for between 30 and 45 minutes, in contrast to the 6.2 minutes provided by GPs, on average.
One very good reason to prefer to see a private consultant is location. HCA's six hospitals in London are in central locations. The Portland Hospital for Women and Children is on Great Portland Street in the West End of London, linking Oxford Street with Albany Street. The Princess Grace Hospital is on Nottingham Place in the City of Westminster, where the nearest tube station is Baker Street. The London Bridge Hospital is on Tooley Street, overlooking the River Thames and Tower Bridge and close to the City of London.
The Lister Hospital is on Chelsea Bridge Road in Chelsea, on the north side of the Thames, near Sloane Square tube station and the Victoria mainline and tube station. The Wellington Hospital is on Wellington Place, slightly north of the West End. These are locations in which people often find themselves.
If a condition is diagnosed, the most common reason for people to seek private health coverage is that the infamous NHS waiting lists are bypassed. NHS waiting lists for the most oft-used procedures were recently reported to have risen by a third. If the pain or discomfort of a condition is preventing your child from leading a normal life, you'll want them to be treated immediately, rather than in as many as 18 weeks down the line, as would be the case of the NHS. With HCA hospitals, there is sometimes no waiting time at all.
With in-hospital stays, private healthcare provides a private en-suite room, television and a choice of food. Visiting hours aren't restricted, which is considerably more convenient for a child's parents.
In all, bringing her child to a private consultant will provide appreciable benefits to a mother who has other demands on her time and to the child.
This is a sponsored post | medical |
https://www.markaicode.com/the-impact-of-machine-learning-on-healthcare-fraud-detection/ | 2024-02-27T20:29:16 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947474686.54/warc/CC-MAIN-20240227184934-20240227214934-00864.warc.gz | 0.936785 | 3,850 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__163471180 | en | In the world of healthcare, trust and accuracy are paramount. However, like any industry, healthcare is not immune to fraudulent activities that seek to exploit loopholes for personal gain. These fraudulent activities not only drain precious resources but also jeopardize patient care and trust in the system.
As healthcare fraud becomes increasingly sophisticated, traditional methods of detection are falling short in their ability to keep up. Enter machine learning, a cutting-edge technology that has revolutionized various industries. By harnessing the power of advanced algorithms and data analysis, machine learning has emerged as a promising tool in the ongoing battle against healthcare fraud.
This article explores the impact of machine learning on healthcare fraud detection, delving into its applications, benefits, and challenges. From identifying patterns in vast amounts of data to flagging suspicious claims in real time, machine learning holds the potential to transform the way we combat fraud in healthcare. By shedding light on this emerging field, we aim to provide an in-depth understanding of the ways in which machine learning is driving change and amplifying the effectiveness of fraud detection methods in the healthcare industry.
1. Introduction: Unleashing the Power of Machine Learning for Healthcare Fraud Detection
In today’s modern world, healthcare fraud has become a pressing issue that poses significant challenges for both insurance companies and healthcare providers. The sheer scale of fraudulent activities in the healthcare industry has resulted in substantial financial losses and compromised patient care. Traditional methods of fraud detection have proven to be inadequate, prompting the need for innovative solutions that can effectively combat these fraudulent activities. This is where the power of machine learning comes into play.
Machine learning, a subfield of artificial intelligence, has gained significant prominence in recent years due to its ability to analyze large volumes of data and detect patterns that are not easily discernible to humans. By leveraging advanced algorithms and statistical models, machine learning systems can identify anomalies and flag potentially fraudulent activities in real-time, ensuring timely intervention and prevention. Applying machine learning techniques to healthcare fraud detection has the potential to revolutionize the healthcare industry, leading to significant improvements in cost savings, operational efficiency, and patient outcomes.
The purpose of this article is to delve deeper into the power of machine learning for healthcare fraud detection and explore the various ways in which it can be leveraged to tackle this pervasive issue. We will discuss the benefits of using machine learning, such as increased accuracy, reduced false positives, and improved scalability. Additionally, we will explore different machine learning algorithms commonly used in fraud detection, including anomaly detection, classification models, and clustering techniques. Furthermore, we will examine real-world examples and case studies highlighting the successful implementation of machine learning in healthcare fraud detection. Stay tuned as we uncover the potential of this cutting-edge technology and its invaluable contribution in combating healthcare fraud.
2. Evolution of Fraud Detection in Healthcare: From Traditional Methods to Machine Learning
With the rapid growth of healthcare data and an increasing number of fraudulent activities, the need for effective fraud detection methods has become paramount in the healthcare industry. Traditional methods of detecting fraud in healthcare, such as manual auditing and rule-based systems, have been in use for many years. However, these methods have their limitations and are often unable to keep up with the constantly evolving techniques used by fraudsters.
Machine learning, on the other hand, has emerged as a promising solution for fraud detection in healthcare. By using algorithms and advanced data analytics techniques, machine learning models are able to analyze large volumes of healthcare data and identify patterns and anomalies that may indicate fraudulent activities. These models are trained on historical data, allowing them to learn from past instances of fraud and continuously improve their accuracy over time.
One key advantage of machine learning-based fraud detection in healthcare is its ability to adapt to changing fraud patterns. Fraudsters are constantly evolving their techniques to evade detection, making it essential for fraud detection methods to be dynamic and flexible. Machine learning models can adapt to new patterns and anomalies by continuously updating their algorithms and incorporating new data. This ensures that healthcare organizations can stay one step ahead of fraudsters and detect fraudulent activities in real time.
Additionally, machine learning models can enhance the efficiency of fraud detection in healthcare by automating the process. Manual auditing and rule-based systems are time-consuming and often prone to errors. Machine learning models, on the other hand, can process large volumes of data in a fraction of the time, making it possible to detect fraud more quickly and accurately. This not only saves valuable resources for healthcare organizations but also allows them to focus on providing quality care to patients.
The evolution of fraud detection in healthcare from traditional methods to machine learning has revolutionized the way fraudulent activities are detected and prevented. Machine learning models offer a dynamic, flexible, and efficient solution to combat fraud in healthcare by analyzing large volumes of data and continuously adapting to changing fraud patterns. With their ability to detect fraudulent activities in real time and automate the detection process, machine learning models have become an invaluable tool for healthcare organizations in their fight against fraud.
3. Leveraging machine Learning Algorithms: Enhancing Accuracy and Efficiency in Healthcare Fraud Detection
In today’s fast-paced healthcare environment, the accurate detection and prevention of fraud are of utmost importance. Leveraging machine learning algorithms has emerged as a powerful tool that can significantly enhance accuracy and efficiency in healthcare fraud detection. These algorithms are capable of analyzing large volumes of data with speed and precision, enabling the identification of patterns and anomalies that might go unnoticed by traditional methods.
One key advantage of machine learning algorithms is their ability to adapt and learn from new data over time. By continuously feeding the algorithms with real-time information, they can improve their performance and detect emerging fraud patterns more effectively. This adaptive nature ensures that healthcare organizations stay one step ahead of fraudsters, who are constantly finding new ways to exploit vulnerabilities in the system.
Moreover, machine learning algorithms can perform a variety of complex tasks in fraud detection, such as anomaly detection, clustering, and classification. Anomaly detection allows the algorithms to identify irregularities in data that might signify fraudulent activities. By analyzing patterns in data, the algorithms can cluster entities into different groups based on their similarities, making it easier to identify suspicious behavior. Classification algorithms can then be used to predict whether a particular claim or transaction is likely to be fraudulent or not.
By leveraging machine learning algorithms, healthcare organizations can achieve higher accuracy rates in fraud detection, significantly reducing false positives and negatives. This not only saves time and resources but also helps protect the integrity of the healthcare system by ensuring that fraudsters are promptly identified and prosecuted.
The use of machine learning algorithms in healthcare fraud detection is revolutionizing the way organizations combat fraudulent activities. These algorithms offer unparalleled accuracy and efficiency, enabling automated analysis of vast amounts of data and the identification of complex patterns. By embracing this technology, healthcare organizations can stay at the forefront of fraud detection and ensure the integrity and sustainability of their operations.
4. Real-time Detection: How Machine Learning is Revolutionizing the Fight Against Healthcare Fraud
Machine learning has emerged as a powerful tool in the fight against healthcare fraud, providing real-time detection capabilities that are revolutionizing the industry. By leveraging sophisticated algorithms and vast amounts of data, machine learning is aiding in the identification and prevention of fraudulent activities, potentially saving billions of dollars each year and improving the overall integrity of the healthcare system.
One of the key ways in which machine learning is transforming the fight against healthcare fraud is through its ability to detect patterns and anomalies. Traditional methods of fraud detection often rely on manual analysis and rule-based systems, which can be time-consuming and limited in their effectiveness. Machine learning, on the other hand, can rapidly analyze vast amounts of data, identifying patterns that may be indicative of fraudulent activity. By continuously learning and adapting, these algorithms can stay one step ahead of fraudsters, helping to prevent fraudulent claims before they are paid out.
In addition to pattern detection, machine learning is also enhancing the speed and accuracy of fraud detection. Real-time monitoring allows for immediate identification of suspicious activity, enabling swift action to be taken to prevent further harm. Machine learning algorithms can also take into account a wide range of variables and factors when assessing the likelihood of fraud, improving the accuracy of prediction and reducing the incidence of false positives.
Moreover, machine learning is enabling the healthcare industry to better analyze and understand fraud patterns. Through the use of sophisticated analytics tools, healthcare organizations can gain insights into common fraud schemes, identifying trends and vulnerabilities that may have previously gone unnoticed. This information can be used to develop targeted strategies and interventions, making it more difficult for fraudsters to operate undetected.
Overall, machine learning is playing a pivotal role in the fight against healthcare fraud, revolutionizing the way fraud detection and prevention are approached. Through its ability to detect patterns and anomalies, provide real-time monitoring, and offer valuable insights, machine learning is helping to safeguard the integrity of the healthcare system and protect both patients and providers. As technology continues to advance, the potential for machine learning to further enhance fraud detection efforts is vast, making it an invaluable asset in the ongoing battle against healthcare fraud.
5. Overcoming Challenges: Ethical Considerations and Implementation Hurdles in Machine Learning for Healthcare Fraud Detection
As machine learning continues to revolutionize the healthcare industry, one area that holds immense potential is fraud detection. Machine learning algorithms have the ability to analyze large datasets and detect patterns that may indicate fraudulent activities. However, implementing machine learning for healthcare fraud detection comes with its own set of challenges, both ethical and technical.
When it comes to ethical considerations, one of the primary concerns is maintaining patient privacy and confidentiality. The use of machine learning algorithms requires access to a vast amount of patient data, including personal health information. To mitigate privacy risks, healthcare organizations must ensure that proper security measures, such as data encryption and access controls, are in place.
Additionally, clear and transparent consent processes should be implemented to obtain patient permission for the use of their data in fraud detection algorithms. By prioritizing patient privacy, healthcare organizations can maintain the trust of their patients while harnessing the power of machine learning for fraud detection.
Another ethical consideration is the potential for bias in machine learning algorithms. Bias can arise from the underlying data used to train the algorithms, leading to unfair treatment of certain individuals or populations. It is essential for healthcare organizations to regularly monitor and evaluate machine learning models to identify and rectify any biases. By using diverse and representative datasets during the training phase, healthcare organizations can minimize bias and ensure fair outcomes.
In addition to ethical considerations, the implementation of machine learning for healthcare fraud detection also faces technical hurdles. One of the primary challenges is the availability and quality of data. Machine learning algorithms require large amounts of high-quality data to be trained effectively. However, healthcare fraud data is often limited and highly imbalanced, with a small number of fraudulent cases compared to a vast number of legitimate cases.
Dealing with such imbalanced datasets can be challenging, as the algorithms may struggle to detect fraud accurately. Healthcare organizations must invest in data collection and curation processes to ensure they have sufficient and representative data for training their machine learning models. Another technical challenge is ensuring the interpretability and explainability of machine learning models in healthcare fraud detection.
With the complex nature of machine learning algorithms, it can be difficult to understand the reasoning behind their predictions. This lack of interpretability raises concerns, as healthcare professionals and regulatory bodies may struggle to trust decisions made by these black-box models. Healthcare organizations must focus on developing interpretable models that provide clear explanations for their fraud detection findings. This not only ensures transparency but also allows healthcare professionals to identify potential flaws or biases in the models.
The application of machine learning for healthcare fraud detection holds tremendous potential in improving the detection and Prevention of fraudulent activities. However, it is crucial to address the ethical considerations surrounding patient privacy and bias, while also overcoming the technical hurdles of data availability, quality, and interpretability. By navigating these challenges, healthcare organizations can leverage the power of machine learning to enhance fraud detection and ultimately protect the integrity of the healthcare system.
6. Future Outlook: Embracing the Potential of Machine Learning to Safeguard Healthcare Systems
The integration of machine learning in healthcare systems has the potential to revolutionize the way we safeguard patient health. With advancements in technology and the increasing availability of data, machine learning algorithms can help healthcare professionals make more accurate diagnoses, predict diseases before symptoms appear, and improve patient outcomes. Here, we explore the promising future outlook of machine learning in healthcare and its potential to transform the industry.
One of the key areas where machine learning can have a profound impact is in disease detection and diagnosis. By analyzing vast amounts of medical data, machine learning algorithms can identify patterns and correlations that may be overlooked by human physicians. This can lead to earlier and more accurate diagnoses, allowing for prompt and effective treatment. Additionally, machine learning models can continuously learn from new data, enhancing their diagnostic capabilities over time.
Q: How has machine learning technology transformed healthcare fraud detection?
A: Machine learning has had a profound impact on healthcare fraud detection by enabling faster and more accurate identification of fraudulent activities. Traditional methods of detecting healthcare fraud were often time-consuming and relied heavily on manual investigation, making it difficult to keep up with the rapidly evolving techniques used by fraudsters. However, with the use of machine learning algorithms, healthcare providers and insurers can now efficiently analyze large volumes of data, detect patterns, and identify potential cases of fraud in real time.
Q: What are the key advantages of using machine learning for healthcare fraud detection?
A: One of the main advantages of using machine learning in healthcare fraud detection is its ability to continuously learn and adapt to new fraud patterns. Machine learning models can be trained on vast amounts of historical data to recognize fraudulent activities based on various factors, such as abnormal billing patterns or suspicious claim behaviors. As these models continuously learn from new data, they become more accurate in detecting fraud and can flag potential cases for further investigation. Additionally, machine learning helps in reducing false positives and increasing overall detection rates, resulting in substantial cost savings and improved healthcare system integrity.
Q: Are there any challenges associated with implementing machine learning for healthcare fraud detection?
A: While machine learning offers significant benefits, there are several challenges associated with its implementation in healthcare fraud detection. One major challenge is the availability and quality of data. To develop accurate machine learning models, organizations need access to large amounts of labeled data representing both fraudulent and non-fraudulent activities. However, obtaining such data can be challenging due to privacy concerns and the reluctance of organizations to share sensitive information. Additionally, the interpretability of machine learning algorithms can be a concern, as their decision-making process is often considered a “black box.” This lack of transparency can lead to skepticism and resistance from stakeholders who may be hesitant to fully trust the automated detection systems.
As we delve deeper into the era of technology, the fascinating world of machine learning continues to offer innovative solutions across various sectors. We have explored its profound impact on healthcare fraud detection and the potential it holds for transforming the landscape of healthcare.
Machine learning has taken the fight against healthcare fraud to new heights, allowing professionals to identify fraudulent activities with increased precision and efficiency. Through the intelligent analysis of vast amounts of data, machine learning algorithms can detect patterns and anomalies that humans might miss, thereby preventing fraudulent practices from going unnoticed.
The implementation of machine learning in healthcare fraud detection has significantly reduced the burden on investigators and auditors, who traditionally spent countless hours sifting through data manually. With automated processes enabled by machine learning models, these professionals can redirect their efforts toward critical tasks and investigations that require human expertise and intervention.
Not only does machine learning expedite the detection process, but it also continually adapts and improves itself as it ingests more data. This adaptive feature allows models to stay ahead of evolving fraud schemes and adjust their detection strategies accordingly. As a result, healthcare organizations can safeguard their resources and protect patients from falling victim to fraudulent practices.
Furthermore, the integration of machine learning algorithms with existing systems and databases has streamlined the detection and prevention process. Real-time monitoring, predictive analysis, and early warning systems have bolstered the ability to identify potential fraudsters promptly, thus minimizing financial losses and safeguarding the integrity of the healthcare system.
While machine learning has showcased considerable potential, it is crucial to acknowledge that it is not a magical solution. Its success greatly relies on an ongoing commitment to data quality, model accuracy, and strict cybersecurity measures. Ethical considerations must remain at the forefront, ensuring that the rights and privacy of patients are respected throughout the process.
In conclusion, the impact of machine learning on healthcare fraud detection cannot be overstated. This technology has revolutionized the field, empowering healthcare organizations to mitigate fraud risks, save precious resources, and protect the well-being of patients. With ongoing advancements and a commitment to responsible implementation, the future of healthcare fraud detection holds tremendous potential for a more secure, efficient, and trustworthy healthcare system.
Healthcare fraud costs the US healthcare system billions of dollars every year. To counteract this, organizations have been using increasingly sophisticated technologies, such as machine learning, to detect and prevent it.
Machine learning is a subset of artificial intelligence that utilizes algorithms to analyze data and learn from patterns in the data. In terms of healthcare fraud detection, machine learning algorithms can find patterns in extensive troves of data about individuals and healthcare transactions, making it possible to identify potentially fraudulent activities.
The use of machine learning in healthcare fraud detection has several advantages. It can be used to validate claims more quickly, reducing the amount of time required for manual reviews. It also reduces the amount of bias in the system, which can be an issue in manual reviews. Additionally, since machine learning can help to uncover trends and unknown patterns, it can help to identify cases of fraud that might have otherwise been missed.
Given the potential benefits of machine learning, healthcare organizations have been investing in the technology and incorporating it into their fraud detection systems. Organizations can use it to develop predictive models that can identify suspicious claims and transactions. This in turn can help reduce the financial losses associated with fraud.
Organizations are also turning to machine learning to improve the accuracy of their results and reduce false positives. By using algorithms to analyze the data more efficiently, organizations can identify true cases of fraud and avoid wasting resources by chasing false leads.
In spite of its advantages, however, there are some challenges associated with the use of machine learning in healthcare fraud detection. One such challenge is that it can still be difficult for organizations to interpret the results generated by the algorithms. Additionally, since healthcare fraud is constantly evolving, machine learning algorithms must also be continually trained and updated in order to remain effective.
Overall, machine learning has the potential to revolutionize healthcare fraud detection. By using predictive models aided by machine learning algorithms, organizations can more quickly and accurately identify potentially fraudulent activities. This in turn can help reduce financial losses and improve the overall efficiency of healthcare organizations. | medical |
https://www.onsitemobiledental.com/ | 2021-06-13T02:05:34 | s3://commoncrawl/crawl-data/CC-MAIN-2021-25/segments/1623487598213.5/warc/CC-MAIN-20210613012009-20210613042009-00219.warc.gz | 0.934952 | 1,449 | CC-MAIN-2021-25 | webtext-fineweb__CC-MAIN-2021-25__0__191355690 | en | Allows our dentures to be engraved with the resident’s name during the denture fabrication process.
Low Radiation X-rays
Digital x-rays reduce radiation exposure by 75% or more. This means a higher and safer level of care.
Initial and Annual Exams
Every patient will receive initial exams and annual assessments with or without dental coverage
Full Facility Audits
Used in addition to our routine house visits to eliminate the possibility for deficiencies by the Department of Health
Comprehensive Examinations, Fillings & Restorations, Implants, Crowns & Bridges, Root Canals, Full & Partial Dentures, Deep Cleanings,
Very important to residents of Skilled Nursing Facilities who face challenges in self care due to sensory mobility and cognitive deficits.
Onsite Dental is an innovative and sophisticated mobile dental company that is designed to focus on improving our client’s oral health by eliminating and preventing
Potential problems such as tooth decay, gum disease, bad breath, and oral infections. We currently serve over 5000 residents who reside in Skilled Nursing Facilities, assisted livings, Alzheimer’s units and hospitals, in Southern California. Our team which consists of knowledgeable and compassionate Dentists, Dental Assistants, Dental Hygienists and X-Ray Technicians, visit the Facilities very often and eliminate the need to travel to an outside Dentist. We start with Initial exams, followed by X-Rays and comprehensive dental exam. We then develop individualized and customized treatment plans that meets the dental needs of each resident.
Our professional and highly trained Hygienists visit your residents several times a year as authorized by Medi-Cal. Our focus is mainly on preventive oral care such as x-Rays and cleanings which is crucial in maintaining a healthy life. Preventive oral care can reduce the risks for some life Threatening conditions such as Aspiration Pneumonia and Cardiovascular disease.
Our mission is to provide preventative On-site dentistry to all residents. We utilize state of the art equipment and highly trained professionals to deliver a full range of dental services, providing compassionate and convenient care for the elderly and disabled.
We Specialize in
24 Hour Emergency Services
Full Facility Audits
Routine Exams and Screenings
Full Mobile Hygiene Services
Fast Treatment Authorization Process
Low Radiation Digital X-rays
Fast Response Time
Patient and Staff Education
Annual Inservice Programs
Timely Treatment Plan Completion
3575 Cahuenga Blvd. Ste. #115
Los Angelea, CA 90068
Monday – Friday 8AM – 5PM
Hours of Operation
"Our experience with Onsite has been amazing. The patients as well as the staff really appreciate how they keep the families of each patient involved every step of the way."
“Onsite consistently goes the extra mile to make sure each patient is satisfied from start to finish. They truly have a personalized approach.”
“We switched to Onsite and we coldnt be more pleased. They are fast, efficient, and affordable. Most of all they work hard to meet our needs no matter the circumstance. We could not be more satisfied.”
Meghan Charles, Admin/Svcs
Years of Experience
Doctor Mitra Mashreghi specializes in all aspects of General Dentistry. She earned her Bachelor’s in Science of Nursing (BSN) at University of Kentucky in 1998. She worked as a Registered Nurse for four years and decided to pursue a career in Dentistry. She graduated from University of Kentucky College of Dentistry in 2006 and has since focused her practice on the nursing home, assisted living and hospital patients. She is very compassionate and takes pride in offering the finest patient care and services to each and every patient. Her nursing experience allows her to combine her medical background and knowledge with her dental skills in order to provide quality care to her patients. This is crucial for the residents of long term care facilities, since they are often present with numerous medical conditions. Her combined knowledge and experience allows her to analyze each and every patient closely and develop an ideal treatment plan without jeopardizing the patient’s well being.
Dr. Ayonna Taylor is a Los Angeles native.
She earned her high school diploma from St. Mary's Academy, and then earned a Bachelors degree in Biology from Hampton University in Hampton, VA.
Dr. Taylor earned her dental degree from Howard University College of Dentistry in Washington, D.C. in 1998, and completed a post-graduate General Practice Residency at King-Drew Medical Center.
She continuously refreshes and updates her dental knowledge by taking numerous dental continuing education courses on the latest trends and techniques.
She holds membership in the West Los Angeles Dental Society, California Dental Association, American Dental Association, and Angel City Dental Society.
Dr. Taylor has been practicing dentistry in the Los Angeles area for over 15 years and loves providing quality, professional, and caring service within the community in which she grew up.
Who We Are.....
Onsite Dental is a mobile dental service dedicated to providing high quality, comprehensive dental care. We value excellence, innovation, integrity and strive to make a positive differences in the lives of your residents. We operate a dental service that provides ONSITE care to nursing homes, assisted living facilites, Dementia and Alzheimer's units, and hospitals. Our goal is to provide appropriate, necessary, and cost effective dental care to residents who will otherwise have to travel to see the dentist. The advantage, especially when working with the elderly or disabled residents, is that the care center is a familiar place, so the dental appointment becomes easier and less stressful on the patient and their loved ones. While integrating the patient and their loved ones into the Consultation and Treatment process, everyone involved helps to reach a positive and satisfying outcome.
Meet Our Doctors
OUR CORE FEATURES
Continuity of Care- Our residents are treated by skilled, and compassionate staff. Through regular and consistent service we maintain a lasting relationship with patients and their families. All dentists are fully committed to maintaining the folllow-ups needed to ensure continuity of care.
Communication- Onsite Dental prides itself in maintaining open lines of communication by communicating directly with the families. Follow-up calls are regularly made and records are submitted to the facility staff.
Professionalism- a California based dental service with experience in SNF, Alzheimer’s, Home Care, Hospice, and Hospital dentistry. Comprehensive, and collaborative dental care, numerous years of experience in the art of mobile dentistry, FDA, OSHA, HIPPA, and California Dental Board Compliant.
Convenience- Brings the dental office to you. Competitive fee schedules. Collaborative approach with patients, families, and your staff. Paper work management including copies of progress notes and visit summary list. Ethical and honest treatment that balances your resident’s needs with their health, Behavior, and available resources. General discounts and payment plans available. | medical |
http://amaze-info.blogspot.com/2011/02/ciprofloxacin.html | 2018-07-17T09:58:24 | s3://commoncrawl/crawl-data/CC-MAIN-2018-30/segments/1531676589634.23/warc/CC-MAIN-20180717090227-20180717110227-00526.warc.gz | 0.920252 | 5,704 | CC-MAIN-2018-30 | webtext-fineweb__CC-MAIN-2018-30__0__203733088 | en | |Systematic (IUPAC) name|
|1-cyclopropyl- 6-fluoro- 4-oxo- 7-piperazin- 1-yl- quinoline- 3-carboxylic acid|
|ATC code||J01 S01 S02 S03|
|Metabolism||Hepatic, including CYP1A2|
|Pregnancy cat.||B3(AU) C(US)|
|Legal status||Prescription Only (S4) (AU) POM (UK)|
|Routes||Oral, intravenous, topical (ear drops, eye drops)|
|Y(what is this?)|
Ciprofloxacin is marketed worldwide with over three hundred different brand names. In the United States, Canada, and the UK, it is marketed as Baycip, Ciloxan, Ciflox, Cipro, Cipro XR, Cipro XL, Ciproxin, Prociflor, and most recently, Proquin. In addition, ciprofloxacin is available as a generic drug under a variety of different brand names and is also available for limited use in veterinary medicine.
Ciprofloxacin was first patented in 1983 by Bayer A.G. and subsequently approved by the United States Food and Drug Administration (FDA) in 1987. Ciprofloxacin has 12 FDA-approved human uses and other veterinary uses, but it is often used for unapproved uses (off-label). Ciprofloxacin interacts with other drugs, herbal and natural supplements, and thyroid medications.
History The United States patent was applied for in January 1987, but was not approved until 1996 according to the patent history.
In 2004, ciprofloxacin and levofloxacin together commanded 65% ($3.3 billion) of the global sales of the fluoroquinolone class. The first nine months of 2008 sales for ciprofloxacin were $242 million, as compared to $324 million for Bayer aspirin. Ciprofloxacin has proven to be a blockbuster drug for Bayer A. G., generating billions of dollars in additional revenue. "In 1999, Cipro was the eleventh most prescribed drug in the United States based on new prescriptions, and ranked twentieth in total United States sales. In 1999, Bayer's gross sales of Cipro in the United States were approximately $1.04 billion." The sale of ciprofloxacin increased dramatically following the anthrax scare of 2001. On 24 October 2002, the Bush Administration (2001–2009) announced a deal between the government and Bayer Pharmaceuticals to purchase 100 million tablets of ciprofloxacin at a reduced price of $0.95 per pill. A full course of ciprofloxacin for postexposure prophylaxis (60 days) resulting from this arrangement costs the government $204 per person treated, compared with $12 per person treated with doxycycline, the drug normally used to treat anthrax, a difference of $192.
Generic equivalentsOn 24 October 2001, The Prescription Access Litigation (PAL), filed suit to dissolve an agreement between Bayer and three of its competitors which produced generic versions of drugs (Barr Laboratories, Rugby Laboratories, and Hoechst-Marion-Roussel) that it claimed was blocking access to adequate supplies and cheaper, generic versions of ciprofloxacin. The plaintiffs charged that Bayer Corporation, a unit of Bayer AG, had unlawfully paid the three competing companies a total of $200 million to prevent cheaper, generic versions of ciprofloxacin from being brought to the market, as well as manipulating the price and supply of ciprofloxacin. Numerous other consumer advocacy groups joined the lawsuit. On 15 October 2008, five years after Bayer’s patent had expired, the United States District Court for the Eastern District of New York granted Bayer’s and the other defendants’ motion for summary judgment, holding that any anticompetitive effects caused by the settlement agreements between Bayer and its codefendants were within the exclusionary zone of the patent and thus could not be redressed by federal antitrust law, in effect upholding Bayer’s agreement with its competitors.
Licensed usesThe licensed uses for ciprofloxacin in the United States are as follows:
In the adult population, ciprofloxacin is limited to the treatment of proven bacterial infections such as:
- Urinary tract infections (not recommended as a first-line antibiotic)
- Acute uncomplicated cystitis in females
- Chronic bacterial prostatitis (not recommended as a first-line antibiotic choice)
- Lower respiratory tract infections (not recommended as a first-line antibiotic choice)
- Acute sinusitis (not recommended as a first-line antibiotic choice)
- Skin and skin structure infections
- Bone and joint infections
- Infectious diarrhea
- Typhoid fever (enteric fever) caused by Salmonella typhi
- Uncomplicated cervical and urethra gonorrhea (due to N. gonorrhoeae) – however, this indication is no longer effective in some areas (e.g., Asian countries, United States (including Hawaii), Canada , and Scotland) due to bacterial resistance. Fluoroquinolones are no longer recommended in the USA for this indication.
As well as in combination with other specific drugs:
- Complicated intra-abdominal infections (in combination with metronidazole);
- Empirical therapy for febrile neutropenic patients (in combination with piperacillin)
Current recommendations by the American Academy of Pediatrics note the systemic use of ciprofloxacin in children should be restricted to infections caused by multidrug resistant pathogens or when no safe or effective alternatives are available.
As such, the general opinion stated in 1994 that ciprofloxacin “is not to be considered a suitable agent for use in general practice for the blind initial treatment of chest infections....” does not appear to have changed within these current guidelines.
Antibiotics may not improve the long-term clinical outcome for sinusitis. When prescribed for chronic bronchitis and acute bacterial sinusitis, the use of the fluoroquinolone class offers no compelling advantages over established treatment. Nor does antibiotic treatment help sore throats. The use of antibiotics such as ciprofloxacin to treat bronchitis is to be considered unnecessary and as such exposes the patient to an unacceptable risk of suffering a severe adverse reaction. Additionally, antibiotics have no effect upon viral infections, such as the common head cold or viral respiratory infections.
Note: Ciprofloxacin may be licensed for other uses, or restricted, by the various regulatory agencies worldwide.
AvailabilityCiprofloxacin is available as:
- tablets (100 mg, 250 mg, 500 mg, 750 mg or 1000 mg)
- intravenous solutions (5% and 10%, 100 mL)
- eye and ear drops
See the latest package insert for ciprofloxacin (Cipro) for additional details.
Mode of actionCiprofloxacin is a broad-spectrum antibiotic active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division.
This mechanism can also affect mammalian cell replication. In particular, some congeners of this drug family (for example those that contain the C-8 fluorine) display high activity not only against bacterial topoisomerases but also against eukaryotic topoisomerases and are toxic to cultured mammalian cells and in vivo tumor models. Although quinolones are highly toxic to mammalian cells in culture, its mechanism of cytotoxic action is not known. Quinolone-induced DNA damage was first reported in 1986 (Hussy et al.).
Recent studies have demonstrated a correlation between mammalian cell cytotoxicity of the quinolones and the induction of micronuclei. As such, some fluoroquinolones may cause injury to the chromosome of eukaryotic cells.
There continues to be debate as to whether or not this DNA damage is to be considered one of the mechanisms of action concerning the severe adverse reactions experienced by some patients following fluoroquinolone therapy.
ContraindicationsAs noted above, under licensed use, ciprofloxacin is also now considered to be contraindicated for the treatment of certain sexually transmitted diseases by some experts due to bacterial resistance.
There are only four contraindications found within the 2009 package insert:
- “Coadministration of ciprofloxacin with other drugs primarily metabolized by CYP1A2 results in increased plasma concentrations of these drugs and could lead to clinically significant adverse events of the coadministered drug.”
- “Concomitant administration with tizanidine is contraindicated.”
- “Ciprofloxacin is contraindicated in persons with a history of hypersensitivity to ciprofloxacin, any member of the quinolone class of antimicrobial agents, or any of the product components.”
- “Local I.V. site reactions are more frequent if the infusion time is 30 minutes or less. These may appear as local skin reactions that resolve rapidly upon completion of the infusion. Subsequent intravenous administration is not contraindicated unless the reactions recur or worsen.”
Ciprofloxacin is also considered to be contraindicated within the pediatric population (except for the indications outlined under licensed use above), pregnancy, nursing mothers, and in patients with epilepsy or other seizure disorders.
- Pediatric population
Within the studies submitted in response to a Pediatric Written Request (ciprofloxacin, circa 2004), the rate of atrophy was reported to be 9.3%. Within the BPCA Pediatric Studies Summary for ciprofloxacin, it was stated that the overall incidence of adverse events at six weeks was 41%. This would be consistent with the safety profile found with the other fluoroquinolones studied in the pediatric population. As such, the current ban on the use of the fluoroquinolones in the pediatric population is both reasonable and supported by various clinical studies. The most recent long term study, BAY 0 9867 Cipro Pediatric Use Study (QUIP), which followed pediatric patients from 1999–2008, supports the current expert opinion that the risk of permanent injury continues to outweigh the potential benefits of ciprofloxacin therapy in the pediatric population.
Within the United States, the FDA has stated it is their intention to pursue the licensing of the fluoroquinolones for pediatric use in spite of the evidence presented at that 62 Meeting of the Anti-Infective Drugs Advisory Committee that the fluoroquinolones cause irreversible joint damage in the pediatric population.
Special precautionsThe status of the patient’s renal function and hepatic function must also be taken into consideration to avoid an accumulation that may lead to an overdose and the development of toxicity. Ciprofloxacin is eliminated primarily by renal excretion. However, the drug is also metabolized and partially cleared through the liver and the intestines. Modification of the dosage is recommended using the table found within the package insert for those with impaired liver or kidney function. However, since the drug is known to be substantially excreted by the kidneys, the risk of toxic reactions to this drug may be greater in patients with impaired renal function. The duration of treatment depends upon the severity of infection and is usually 7 to 14 days.
Adverse effectsSerious adverse events occur more commonly with fluoroquinolones than with any other antibiotic drug classes. In most, adverse reactions are mild to moderate; however, occasionally serious adverse effects occur. There have been a number of regulatory actions taken as a result of such adverse reactions, which included published warnings, additional warnings and safety information added to the package inserts together with the issuance of "Dear Doctor Letters" concerning the recent addition of Black Box Warnings. In 2004, the U.S. FDA requested new warning labels to be added to all of the fluoroquinolones, including ciprofloxacin, regarding peripheral neuropathy (irreversible nerve damage), tendon damage, heart problems (prolonged QT Interval / torsades de pointes), pseudomembranous colitis, rhabdomyolysis (muscle breakdown), Stevens-Johnson syndrome, as well as concurrent usage of NSAIDs contributing to the severity of these reactions.
Subsequent to this, on 25 June 2007, the U.S. FDA required the manufacturer to add an additional warning to the package inserts that stated “Other serious and sometimes fatal events, some due to hypersensitivity, and some due to uncertain etiology, have been reported in patients receiving therapy with quinolones, including ciprofloxacin.” It was not until 2008, (four years later) that the label revisions for ciprofloxacin included any warnings concerning heart problems (prolonged QT interval / torsade de pointes). Warnings concerning rhabdomyolysis and Stevens-Johnson syndrome are still conspicuously absent from the package inserts as of September 2009.
The serious adverse effects that may occur as a result of ciprofloxacin therapy include irreversible peripheral neuropathy, spontaneous tendon rupture and tendonitis, acute liver failure or serious liver injury (hepatitis), QTc prolongation/torsades de pointes, toxic epidermal necrolysis (TEN), and Stevens-Johnson syndrome, severe central nervous system disorders (CNS) and Clostridium difficile associated disease (CDAD: pseudomembranous colitis), as well as photosensitivity/phototoxicity reactions.
Psychotic reactions and confusional states, acute pancreatitis, bone marrow depression, interstitial nephritis and hemolytic anemia may also occur during ciprofloxacin therapy. Additional serious adverse reactions include temporary, as well as permanent, loss of vision, irreversible double vision, drug induced psychosis and chorea (involuntary muscle movements), impaired color vision, exanthema, abdominal pain, malaise, drug fever, dysaesthesia and eosinophilia. Pseudotumor cerebri, commonly known as idiopathic intracranial hypertension (IIH), (also referred to as increased intracranial pressure), has been reported to occur as a serious adverse reaction to ciprofloxacin.
Children and the elderly are at a much greater risk of experiencing such adverse reactions. Such reactions may manifest during fluoroquinolone therapy, and long after it had been discontinued.
Serious visual complications have also been reported to occur with ophthalmic fluoroquinolone therapy, which may also occur with ciprofloxacin eye drops, especially corneal perforation, but also evisceration and enucleation. This increased incidents of corneal perforation may be due to fluoroquinolones causing alterations in stromal collagen, leading to a reduction in tectonic strength. As noted previously permanent double vision (diplopia) has also been reported. An unusual case of seizures has also been reported with ciprofloxacin ear drops in an elderly patient.
Some groups refer to these adverse events as "fluoroquinolone toxicity". These groups of people claim to have suffered serious long term harm to their health from using fluoroquinolones. This has led to a class action lawsuit by people harmed by the use of fluoroquinolones, as well as legal action by the consumer advocate group Public Citizen. Partly as a result of the efforts of the State of Illinois and Public Citizen, the FDA ordered black box warnings on all fluoroquinolones advising consumers of the possible toxic effects of fluoroquinolones on tendons.
InteractionsThe toxicity of drugs that are metabolised by the cytochrome P450 system is enhanced by concomitant use of some quinolones. Coadministration may dangerously increase coumarin (warfarin) activity; INR should be monitored closely. They may also interact with the GABA A receptor and cause neurological symptoms; this effect is augmented by certain nonsteroidal anti-inflammatory drugs. Quercetin, a flavonol, occasionally used as a dietary supplement, may interact with fluoroquinolones, as quercetin competitively binds to bacterial DNA gyrase. Some foods, such as garlic and apples, contain high levels of quercetin; whether this inhibits or enhances the effect of fluoroquinolones is not entirely clear. Ciprofloxacin can reduce phenytoin plasma levels, which may, in some cases, result in seizures. Ciprofloxacin may interfere with the levels of thyroid medications resulting in hypothyroidism.
On 9 November 2005, the U.S. FDA required the manufacturers to provide additional warnings within the package inserts concerning ciprofloxacin being an inhibitor of human cytochrome P450 1A2 (CYP1A2) mediated metabolism. The new warning stated:
"Coadministration of ciprofloxacin with other drugs primarily metabolized by CYP1A2 results in increased plasma concentrations of these drugs and could lead to clinically significant adverse events of the coadministered drug."Concurrent administration of ciprofloxacin with magnesium or aluminum antacids, sucralfate or products containing calcium, iron, or zinc (including multivitamins or other dietary supplements) may substantially decrease the absorption of ciprofloxacin, resulting in serum and urine levels considerably lower than desired.
Significant drug interactionsCiprofloxacin can alter and be altered by the metabolism and effects of other drugs, resulting in some significant drug-drug interactions that may affect the musculoskeletal, central nervous, renal, and other systems.
Current or past treatment with oral corticosteroids is associated with an increased risk of achilles tendon rupture, especially in elderly patients who are also taking the fluoroquinolones. This is the subject of Black box warnings in FDA and BNF labeling for quinolones.
The Committee on the Safety of Medicines and the FDA warn that central nervous system adverse effects, including seizure risk, may be increased when NSAIDs are combined with quinolones. The interaction between quinolones and NSAIDs is important, because it has the potential for considerable CNS toxicity. The mechanism for this interaction is believed to be due to a synergistic increased antagonism of GABA neurotransmission.
Ciprofloxacin's renal clearance may affect other drugs subject to renal clearance or otherwise affecting the kidney. The use of ciprofloxacin concomitantly with cyclosporine has also been associated with transient elevations in serum creatinine. Renal tubular transport of methotrexate may be inhibited by concomitant administration of ciprofloxacin, potentially leading to increased plasma levels of methotrexate and risk of methotrexate toxicity. Probenecid interferes with renal tubular secretion of ciprofloxacin and produces an increase in the level of ciprofloxacin in serum.
Some quinolones, including ciprofloxacin, exert an inhibitory effect on the cytochrome P-450 enzyme CYP1A2, thereby reducing clearance, and thus increasing blood levels of tizanidine and methylxanthines (e.g., theophylline and caffeine). The quinolones have also been reported to enhance the effects of warfarin or its derivatives. Such interactions can augment the effects of the co-administered drug, including adverse effects. Ciprofloxacin can reduce effects of other drugs; for example, it has been shown to interact with thyroid medications (levothyroxine), resulting in unexplained hypothyroidism. Altered serum levels of phenytoin (increased and decreased) have been reported in patients receiving concomitant ciprofloxacin.
OverdoseOverdose of ciprofloxacin may result in reversible renal toxicity. Treatment of overdose includes emptying of the stomach via induced vomiting or by gastric lavage. Careful monitoring and supportive treatment, monitoring of renal function and maintaining adequate hydration is recommended by the manufacturer. Administration of magnesium, aluminum, or calcium containing antacids can reduce the absorption of ciprofloxacin. Hemodialysis or peritoneal dialysis removes only less than 10 percent of ciprofloxacin. Ciprofloxacin may be quantitated in plasma or serum to monitor for drug accumulation in patients with hepatic dysfunction or to confirm a diagnosis of poisoning in acute overdose victims.
ChemistryCiprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C17H18FN3O3 and its molecular weight is 331.4 g/mol. It is a faintly yellowish to light yellow crystalline substance.
Ciprofloxacin hydrochloride (USP) is the monohydrochloride monohydrate salt of ciprofloxacin. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8 g/mol. Its empirical formula is C17H18FN3O3HCl•H2O.
PharmacokineticsThe effects of 200–400 mg of ciprofloxacin given intravenously are linear; drug accumulation does not occur when administered at 12 hour intervals. Bioavailability is approximately 70-80%, with no significant first pass effect. IV administration produces a similar serum levels as those achieved with administration of 500 mg administered orally. IV administration over 60 minutes given every 8 hours produces similar serum levels of the drug as 750 mg administered orally every 12 hours. Biotransformation is hepatic. The elimination half life is 4 hours.
History of the black box warningsMusculoskeletal disorders attributed to use of quinolone antibiotics were first reported in the medical literature in 1972, as an adverse reaction to nalidixic acid. Rheumatic disease after use of a fluoroquinolone (norfloxacin) was first reported eleven years later. In response to a 1995 letter published in the New England Journal of Medicine, representatives of the U.S. Food and Drug Administration (FDA) stated that the agency would "update the labeling [package insert] for all marketed fluoroquinolones to include a warning about the possibility of tendon rupture."
By August 1996, the FDA had not taken action, and the consumer advocacy group Public Citizen filed a petition with the FDA prompting the agency to act. Two months later, the FDA published an alert in the FDA Medical Bulletin and requested that fluoroquinolone package inserts be amended to include information on this risk.
Nine years later, in 2005, the Illinois Attorney General filed a second petition with the FDA again seeking Black Box Warnings and "Dear Doctor" letters emphasizing the risk of tendon rupture; the FDA responded that it had not yet been able to reach a decision on the matter. In 2006, Public Citizen, supported by the Illinois Attorney General, renewed its demand of ten years prior for Black Box Warnings by filing a third petition requesting such changes be made. When the FDA failed to respond to these two petitions as required by law Public Citizen, in January 2008, filed suit to compel the FDA to respond to their 2006 petition. On July 7, 2008 the FDA requested that the makers of systemic-use fluoroquinolones add a boxed warning regarding spontaneous tendon ruptures, and to develop a Medication Guide for patients. The package inserts for Ciprofloxacin, Avelox (moxifloxacin), Proquin XR, Factive (gemifloxacin), Floxin (ofloxacin), Noroxin (norfloxacin) and Levaquin (levofloxacin) were amended on September 8, 2008 to include these new warnings. Bayer, which manufactures Cipro, Avelox and Proquin XR, issued a Dear Healthcare Professional letter on October 22 concerning these changes. Ortho-McNeil, the manufacturers of Levaquin, issued a similar letter in November. through the Health Care Notification Network, a registration-only website that distributes drug alerts to licensed healthcare professionals.
Review of the FDA website indicates that the majority of the generic versions of the fluoroquinolones have not been updated to include this Black Box Warning as of September 2009. Additionally there are numerous reports that this information has not been dessiminated to the pharmacist, the name brand products continue to contain the previous labels that are absent of this warning, and the Medication Guide has not been made available to the pharmicist or physician for distribution.
FDA warning lettersAdditionally the manufacturers of ciprofloxacin (Bayer A.G.) received numerous warning letters from the United States Food and Drug Administration regarding false advertising and failure to provide adequate warnings within their promotional materials.
Overprescribing and bacterial resistanceCiprofloxacin is commonly used for urinary tract and intestinal infections (traveler's diarrhea) and was once considered a powerful antibiotic of last resort, used to treat especially tenacious infections. Not all physicians agreed with this assessment, as evidenced by its wide spread use to treat minor infections as well as non-approved uses. As a result in recent years many bacteria have developed resistance to this drug, leaving it significantly less effective than it would have been otherwise.
Resistance to ciprofloxacin and other fluoroquinolones may evolve rapidly, even during a course of treatment. Numerous pathogens, including Staphylococcus aureus, enterococci, and Streptococcus pyogenes now exhibit resistance worldwide. Widespread veterinary usage of the fluoroquinolones, particularly in Europe, has been implicated.
Fluoroquinolones had become the most commonly prescribed class of antibiotics to adults in 2002. Nearly half (42%) of these prescriptions were for conditions not approved by the FDA, such as acute bronchitis, otitis media, and acute upper respiratory tract infection, according to a study that was supported in part by the Agency for Healthcare Research and Quality. Additionally they are commonly prescribed for medical conditions that are not even bacterial to begin with, such as viral infections, or those to which no proven benefit exist. | medical |
http://www.slimfitmama.com/quick-comparison-botox-dysport/ | 2013-05-18T16:47:49 | s3://commoncrawl/crawl-data/CC-MAIN-2013-20/segments/1368696382560/warc/CC-MAIN-20130516092622-00001-ip-10-60-113-184.ec2.internal.warc.gz | 0.955272 | 665 | CC-MAIN-2013-20 | webtext-fineweb__CC-MAIN-2013-20__0__1269134 | en | A Quick Comparison Between Botox And Dysport
Botox and Dysport are both cosmetic surgery solutions that have been derived from the same toxin and serve essentially the same purpose: paralyzing the muscles in the area in order to eliminate the wrinkles and lines generate by motion (facials expressions like frowning, laughing or smiling for instance). At the same time, both products have received the FDA seal of approval, even though Botox has been available on the US market much longer compared to Dysport. However, it is necessary to point out that even though Dysport manufacturers have received the US green light more recently, it has been frequently used in Europe and Canada. By the end of this article, you will find out how Botox and Dysport score in terms of speed, duration, safety and costs.
Time Taken For First Visible Results
In regards to the timeframe between the injection and the first visible results, Dysport has proven slightly superior to Botox (at least for 30 percent of the people in this study). This means that while individuals who utilized Botox injections had to wait for 2-3 days before the effects of the substance became prominent, it is entirely possible that the initial results of Dysport become visible on the very first day. On the other hand, keep in mind that this only refers to the initial results and not the full effect of the injection, which on average is similar for both of them.
Duration of Effect
As far as the duration of the effect is concerned, several clinical trials have shown that Botox is just slightly better than Dysport. However, other studies revealed the opposite results and consensus among cosmetic surgeon boards is yet to be reached. The most probable reason for the diverse testing results resides in the lack of normalization for the quantity of substance injected among the subjects of the studies. In other words, there is a direct correlation between the quantity of substance utilized and the length of the period when the results are visible.
It is also necessary to point out that the quantity of Dysport necessary to obtain the same results as Botox is 2.5 times larger. This means that 1 unit of Botox converts into approximately 2.5 units from the Dysport solution. Now, the larger quantity of Dysport (and its consistence) means that it has the potential of spreading easier within the area, but that has positive and negative consequences. To put it simply, it makes Dysport more effective for eliminating the wrinkles in larger zones (such as the forehead) but less convenient for localized usage (eyebrows or eyes).
Let’s Talk Money
From the financial point of view, one unit of Dysport is cheaper than one unit of Botox by approximately 5 to 10 percent. However, don’t forget about the conversion rates discussed previously. Depending on the type of procedure, you may be able to utilize less Dysport and therefore it could constitute the more profitable alternative. In order to learn which product would prove more proficient in treating your particular type of wrinkles, it is advisable to schedule a consultation with your cosmetic surgeon and assess the state of your epidermis, facial structure, potential side effects and so on.
Filed under: General Health
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http://www.vedicsociety.org/nasya-karma-as-per-classical-texts-a-366.html | 2016-04-29T17:50:02 | s3://commoncrawl/crawl-data/CC-MAIN-2016-18/segments/1461860111392.88/warc/CC-MAIN-20160428161511-00116-ip-10-239-7-51.ec2.internal.warc.gz | 0.791668 | 11,671 | CC-MAIN-2016-18 | webtext-fineweb__CC-MAIN-2016-18__0__290802 | en | Aacharya Vagbhata: ( A. S. Su. 29)
Definition of Nasya karma: The procedure of instilling medicines through the nasal orifice is called Nasya karma.
The nasal orifices are believed to be the entrance of the head. The medicine instilled through them easily penetrates the Sringataka and spreads to the Siras (arterioles) of head(shira), eyes(netra), ears(shrotra), throat(kantha) and expels out the impurities.
Types of nasya karma:
According to the functions the nasya karma is of 3 types.
- Virechana nasya.
- Brihmana nasya
- Shamana nasya.
According to the quantity of the nasya drug used it is of 2 types.
- Marsha nasya
- Pratimarsha nasya.
It is mainly indicated in the diseases of head caused by Kapha dosha or its predominance like:
- Heaviness of the head(adhigaurava)
- Swelling or tumor in the head(shopha)
- Feeling as if something sticking on the head(upadeha)
- excess secretions(srava)
- excess salaivation(praseka)
- Loss of taste(arochaka)
- hoarseness of the voice(swarabheda)
- worm infestation in the head(krimi)
- loss of smell(gandha agnana)
- Ring worm infestation(dadru)
Which form of the shirovirechana drugs should be used here?
- Decoction(Kwatha), powder(choorna),fresh juices(swarasa), unctuous substance(sneha) prepared with the shirovirechana drugs.
- Honey(madhu), salt(saindhva), fermented products(aasava), pitta(bile juice), Urine(mootra) mixed with the shirovirechana drugs can be used.
- Drugs and their preparations can be decided according to the disease.
- For persons timid or fearful(bheeru), lady(stree), imatiated(krisha), tender and delicate(sukumara), the virechana nasya drug should be used in the unctous(sneha) form.
- In the conditions like Diseases of throat(galaroga), fever due to vitiation of three doshas(sannipata jwara), excess sleep(atinidra), psychological disorders(manovikara), diseases of the head due to worms(krimija shiroroga), twitching of the eye(akshi spandana), disorders of vision(timira), krichra, Poison(vish peedita), conjunctivitis(abhishyanda), snake bite(sarpadamstra), loss of conciousness(visamjna) virechana nasya drug should be used in the powder form.
These conditions need quick acting drugs as they have highly aggravated doshas.
Powders(choorna) create vegas simply by keeping it near the nostril.
- Indicated in vataja or vata predominant diseases like-migraine( Sooryavarta)
- diseases of head due to worms(krimija shiroroga)
- constriction of the eyes( akshi sankocha)
- tremors of the eyes( akshi spandana)
- defects of the vision(timira)
- difficulty in getting up from sleep(krichravabobhaka)
- toothache(danta shoola)
- tinnitus(karma nada)
- dryness of nose and the oral cavity( nasa mukha shosha)
- difficulty in speech(vaksanga)
- hoarshness of voice(swaropaghata)
- diseases of nape region(manya roga)
- frozen shoulder(avabahuka)
- insomnia(nidra naasha).
Which form of nasya drug should be selected here?
- Unctuous substance(sneha)
- exudation of trees or gum(niryasa)
- meat soup (mamsa rasa) and blood(rakta) processed with sweet and unctuous drugs which are indicated in the treatment of those particular conditions are used in the above conditions.
- Indicated in diseases due to the vitiation of blood and pitta ( raktaja and pittaja) like premature wrinkles(akaala vali)
- premature graying of hairs(palita)
- hair fall ( khalitya)
- psoriasis of the scalp(daarunaka)
- redness of the eyes(raktaraaji)
- blackish discoloration on face (vyanga)
- bleeding from nose(raktapitta).
Which form of the drug should be used here?
- Unctuous substance(sneha), fresh juice(swarasa) of the drugs indicated in the treatment of that particular condition are used.
- Milk(ksheera), water(udaka) are also used.
- In the balanced state of the humors(samyavastha ) or in healthy condition anu thaila can be used.
Different names of the nasya karma depending on the preparation of the drug:
- Avapeeda nasya: Virechana or shamana nasya where the paste of the drug(kalka) is squeezed into the nostril is called avapeeda nasya.
- Pradhamana nasya: Virechana nasya where the powder(choorna) is used is called pradhamana nasya.
- The main purpose of all nasyas is to expell the kapha dosha(Kapha virechana) from the head. So all nasya karmas are called as virechana nasya. When strong drugs are used in the virechana nasya karma it is called as shirovirechana nasya.
Quantity of the unctuous medicine in marsha nasya:
- Uttama maatra ---------10 bindu
- Madhyama maatra ------ 8 bindu
- Hrswa maatra ----------- 6 bindu
Quantity of decoction in marsha nasya:
- Uttama maatra --------- 8 bindu
- Madhyama maatra ---- 6 bindu
- Hrswa maatra ---------- 4 bindu.
Bindu: The amount of the liquid trickling down from the index( pradeshini) finger which is dipped in the liquid up to the 2nd interphalangal joint and taken out is called one Bindu.
Quantity of the powder in the pradhamana nasya:
The quantity of powder required to reach the throat (kantha) when blown through a 6angula long pipe is the quantity for pradhamana nasya. This can be repeated multiple times depending on the intensity of the doshas.
Marsha nasya is contraindicated before the age of 7years and after the age of 80 years.
Nasya Kala: ( Proper Time To Administer Nasya)
- In Vata predominant diseases the nasya should be administered in the evening(aparaahnna)
- In Pitta predominant diseases the nasya should be administerd in the noon(madhyaahnna).
- In Kapha predominant diseases the nasya should be administered in the morning(poorvahnna).
- In conditions like excessive salivation(lalasrava), talking in the sleep(supta pralapa), teeth biting(dantakatakatayana), making different sounds from the throat in the sleep(krathana), difficulty in opening the eyelids(krichronmeelana), foul odor from the mouth(pootimukha), tinnitus(karma naada), thirsty(trishna), facial paralysis(ardita), diseases of the head(shiroroga), difficulty in breathing(shwasa), cough(kaasa), insomnia(anidra), the nasya should be administered in the night(raatri).
- In order to maintain the health(swsthavritta) and in the cold season(sheeta ritu) the nasya should be done in the noon(madhyahnna).
- In sharad ritu and in vasanta ritu the nasya should be done in the morning(praahnna).
- In greeshma ritu it should be done in the evening(aparaahnna).
- In varsha ritu it should be done whenever the sun is visible(aaditya darshane) in the sky.
- While administering the panchakarma procedures it should be done after the completion of medicated enema( vasti karma).
Contraindications For Nasya Karma:
- One who has taken food(bhukta bhakta)
- One who has taken unctuous substance(sneha peeta)
- one who has taken alcohol, water, or desirous of drinking them
- One who has gara visha in his body
- one who has taken head bath or one who wants to take head bath
- Siradivyadha sruta rakta( one who is bleeding due to the blood letting by puncturing the veins or any other causes)
- One who has urge for passing urine, stools etc
- One who is suffering from injuries(abhihata)
- immediately after vamana, virechana, basti karma, pregnant lady, first 45days after delivery(sootika), acute coryza (navapratishyaya),breathing difficulty( shwasa), cough(kasa), amenorrhea (anartava) and durdina(inauspicious day). In these conditions the nasya karma should not be performed.
Effects of nasya in above conditions:
- Nasya administered immediately after the intake of food makes the stimulated doshas to move in the upward direction and causes vomiting, breathing difficulty(shwasa), cough(kasa), coryza(pratishyaaya).
- The nasya administered to a person who has taken unctuous substance or who is going to take unctuous substance will destroy the secretions of his eyes, nose, oral cavity and causes defects of the vision(timira roga), diseases of the head(shiroroga).
- Nasya administered to a person who had his head bath causes head ache (shira shoola), pain in the eyes(akshi shoola), pain in the ears(karma shoola), diseases of the throat(kantha roga), rhinitis(peenasa), lock jaw(hanusthambha), stiffness in the nape region(manya stambha), facial paralysis(ardhita), tremors of the head( shira kampa).
- Nasya administered to a person who is going to take bath will cause stiffness in the head, sluggishness of the head( shirojaadyatwa), tastelessness(aruchi), rhinitis(peenasa).
- Nasya administered to the bleeding person causes emaciation( kshamata or krishata), tastelessness(aruchi), weak digestive fire(agnimaandya).
- Nasya administerd to a person who has suppressed the natural urges(vegas) like urination, defication, etc leads to the diseases caused by suppressing those particular natural urges.
- Nasya karma in injured person aggravates the pain.
- Nasya karma immediately after emesis(vamana), purgation(virechana), medicated enema(bastikarma) causes breathing difficulty(shwasa), cough(kasa), destruction of voice(swara haani), destruction of sense organs(indriya haani), heaviness in the head(shirogaurava), itching(kandu), worm infestation(krimi dosha).
- Nasya karma in pregnant lady causes hatred ness towards food( bhakta dwesha), fever(jwara), syncope(moorcha), hemicrania(ardhavabedhaka) to the mother, and causes blackish discoloration of the facial skin(vyanga), anomalies (vikalendriyatwa), mental disorders(unmada), epilepsy(apasmara) to the child.
- Nasya karma to a lady within the first 45days of the delivery (sootika) will cause the same effects as in bleeding.
- Nasya karma in acute coryza(navapratishyaya) will cause blockage of the channels(srotorodha), chronic coryza(dushta pratishyaya), hairfall(kesha shaata), worm infestation(krimi), itching(kandu), eczema(vicharchika).
- Nasya in a person suffering from breathing difficulty(shwasa) or cough(kasa) aggravate the condition.
- Nasya done on a wrong time and on a inauspicious day will lead to headache(shiroruk), tremors(vepathu), rigidity(sthaimitya), itching(kandu) and inflammation(paaka) in palate(taalu) and eyes(netra), stiffness in the nape region(manyasthambha), diseases of the throat(kantha roga), coryza(pratishyaya), boils on the scalp(arumshika).
Treatmaents For The Complications:
In case of complications the vaidya should analyze the site of the disease and aggravated doshas and plan the treatments like snehana(oliation), swedana(fomentation), shirolepa(application of the paste on the scalp), vaktra lepa(application of the paste inside the oral cavity), parisheka(pouring the warm liquid on the affected part), teekshna avapeeda, dhooma(medicated smoke), gandoosha, etc.
- When rooksha nasya administered in the pregnant lady milk processed with punarnava, kakoli, kapikacchu or milk processed with bala, vidari, shaliparni, meda is given to drink. Ghee prepared using the same drugs is also used internally.
For shiro vasti and karnapoorana oil processed with vata pacifying drugs is used.
Brihmana (nourishing) food should be given to her.
- In other complications the treatment of that particular disease should be followed.
Nasya Vidhi( Procedure):
- Select a patient suitable for the nasya procedure.
- Identify a good day.
- Just before the nasya procedure the patient finish natural urdes like urination, defecation, etc or the patient should be should be free of all natural urges while administering the nasya.
- His face and the oral cavity should be cleansed.
- He should not be hungry.
- His head should be oileated and fomented, and the channels should be cleaned by prayogika dhoomapana.
- Select a room which is free of breeze.
- The person should lie on his back with extended hands and feet. The feet portion should be slightly raised.
- His supraclavicular part of the body should be fomented with the heat of the palms(paani taapena ) repeatedly.
- The nasya medicine should be divided into three portions and taken in silver or golden or copper or shukti container, and heated by keeping it over the hot water.
- Slightly extend the patient’s head.
- Cover the eyes with a four folded cloth using the left thumb and little finger.
- Slightly lift the tip of the nose using the left middle finger. The left index and ring finger are used to close each nostril while instilling the medicine into the nasal orifice.
- Close one nasal orifice and instill the Luke warm medicine into the other nostril using the right hand. The medicine should be instilled as a uninterrupted flow(dhaara), so it should be taken in a pranaadi(a small vessej which has a pipe like projection) or a cotton swab. Repeat the same procedure on the other side also.
Post operative steps:
- The patient should slowly inhale the instilled medicine.
- Simultaneously his ears, forehead(lalata), Scalp(kasha bhoomi), ganda, nape region(manya), Shoulders(skandha), palms(paani tala), feet(paada tala) are gently massaged.
- When the medicine reaches the throat he should spit it by turning to his right side or left side. He should be instructed not to swallow the medicine. Swallowing the mucus mixed medicine suppress the digestive fire and increases the doshas. Spitting by turning to only one side will prevent the medicine from spreading into all siras(arterioles).
- Until all the medicine comes out repeat the fomentation and patient should repeatedly inhale and spit out the medicine.
- Once instilled medicine comes out completely, repeat the procedure with 2nd and 3rd portion of the medicine after assessing the strength of the doshas etc.
- In case of virechana avapeeda nasya in the post operative procedure one should administer sneha nasya after assessing the strength of the dosha.
- After the completion of the procedure the patient should lie down on his back with eyes open upto 100countings.
- Then to pacify the remaining doshas virechanika dhoomapanam should be done or which ever dhoomapana indicated in that particular condition is administered.
- Warm water gandoosha(gargling) should be done after the dhoomapana(medicated smoking).
- The restrictions explained for post snehapana should be followed here also. But here excess water intake should be avoided.
- Repeat the whole procedure on the 3rd day.
- In hiccough(hikka), derangements of the voice(swaropaghaata), stiffness in the nape region(manya stambha), convulsive disorders(apataanaka) and diseases of the head due to the vitiation of wind(vataja shiroroga) nasya karma can be done once or twice daily. The procedure can be repeated for 5 or 7 or 9 days or till the samyak nasya symptoms appear.
Samyak nasya lakshanas (Effects of proper application of nasya karma):
- Due to the proper oleation and expultion of doshas from the head the person will experiences sukha(strain free) inhalation and exhalation.
- He will get sneezing in proper time.
- His sleeping and waking up will be on time without any discomforts.
- His head(shira), oral cavity(vadana), and sense organs(indriyas) will be clear.
- The condition for which the nasya was done will subside(roga shaanti).
Nasya ayoga lakshanas( Effects of deficient application of nasya karma):
The deficient application of nasya karma will cause vataja diseases.
Nasya atiyoga lakshanas( Effects of excessive application of nasya karma):
The excessive application of nasya karma will cause kaphaja diseases.
Treatments for the complications:
Complications have to be treated according to their respective treatments explained in the other chapters.
What are the effects of ignoring the operative steps?
- The medicine should not be too little. The under dose of the nasya medicine will stimulate the doshas but is unable to expel them out. This causes heaviness(gaurava), tastelessness(aruchi), cough(kasa), excessive salivation(praseka), rhinitis(peenasa), vomiting(chardi) and diseases of the throat(kantha roga).
- Excess medicines instilled into the nasal orifice causes effects of excessive application of the nasya karma(atiyoga lakshanas).
- The complete dose of the medicine should not be instilled at once. By doing so the patient may suffer from excessive oleation of nose and throat(utsnehana), diseases of the head(shiroroga), coryzya(pratishyaya), excess moisture of the nostrils(ghrana kleda), difficulty in inhalation(ucchwasoparodha).
- The medicine should not be too hot. Hot medicine will cause burning sensation(daha), Inflamation(paaka), fever(jwara), bleeding from the nose(raktasrava), head ache(shirovedana), weakness of the vision(dristi daurbalya), unconsciousness (moorccha), giddiness(bhrama).
- The medicine should not be too cold. The cold medicine causes effects of deficient application of the nasya karma(ayoga lakshanas).
- While administering the medicines the head should not be raised. The raised head during the procedure prevents the proper spreading of the medicine in the head and causes ayoga lakshanas.
- The head should not be too low while administering the medicine. In the hyper extended head the medicine spreads fast and deep causing syncope(moorcha), sluggishness or inactivity(jaadya), itching(kandu), burning sensation(daha), fever(jwara).
- The patient should not constrict his body while instilling the nasya medicine. The constricted body prevents the proper spreading of the medicine and proper stimulation of doshas and causes pain, stiffness.
- If the patient becomes unconscious(moorccha) during the procedure due to incompetence of the medicine or due to the vega created by the medicine immediately cold water should be sprinkled all over body except on the head.
- The patient should not laugh, talk, shake, or become angry, inhale the medicine in upward direction (ucchindana ) while instilling the medicine into the nostril. These actions cause headache(shiroruk), catarrh or cold(pratishyaya), cough(kasa), defects of the vosion(timira), hair fall(khalitya), premature graying of hair(paalitya), blackish discoloration of the facial skin(vyanga), mole(tilakaalaka), acnes(mukhadooshika).
- injury to the chest(urakshata)
- dryness of the oral cavity(mukhashosha)
- old age(vriddha)
- tender or delicate personality(sukumara). Pratimarsha nasya can be administered in unseasonable time(akaala)
- inauspicious day(durdina) and rainy season(varsha)
- from birth to death (aajanma marana).
- Chronic catarrha(dushta pratishyaya)
- worm infestation and diseases of head involving multiple doshas(bahudosha krimina shiro)
- one who drank alcohol(madya peeta)
- weakness of the hearing organ(durbala shrotra). Pratimarsha nasya given in these conditions will aggravate the condition as the doshas are in highly aggravated state.
Time for pratimarsha nasya:
Aachaarya Vagbhata explained 15 kaala(time) along with their specialties.
- Praatah kaala (Morning)
- Bhuktavaschante(After the food intake)
- Pratimarsha administerd in these 2 conditions leads to the clarity of the channels(sroto shuddhi), lightness of the head( shirolaaghava), clarity of the mind(manhprasada).
- Vit visarjanante( after defication)
- Mootra visarjanante(after urination)
- After the head massage(shiroabhyanga)
- Kavalante (after gargling)
- Anjanante (after collyrium application)
- Pratimarsha nasya in these conditions leads to clarity of the vision(dristi prasada)
- After danta dhaavana(after brushing the teeth)
- Pratimarsha nasya administered after danta dhavana will lead to strong teeth(danta dridhata), sweetness of the odour(saugandhya).
- Adhwagamanante( afrer long walk)
- Vyayamante( after the exercise)
- Vyavayante ( after the sexual intercourse)
- Pratimarsha in these conditions helps in reducing the tiered ness(shrama), klama, sweat(sweda), stiffness(stambha).
- Divaswapnante( after the day sleep)
- Pratimarsha nasya after the day sleep helps in reducing the sleepy feeling after waking up from the day sleep( nidra shosha), heaviness(gaurava) and gives clarity of the mind(manahprasada).
- atihasitante(after excess laugh)
- Pratimarsha nasya here will pacify the aggravated wind.
- Charditante(after vomitimg)
- Helps to expel the kapha dosha which is sticking inside the channels.
- Dinante( at the end of the day)
- Causes srotoshuddhi(clarity of channels) and proper sleeping and waking up(sukha nidra prabodha).
Quantity of Pratimarsha nasya medicine:
2 or 1 bindu is the quantity of the medicine indicated for Pratimarsha nasya by aacharya vagbhata.
That quantity of the medicine which does not aggravate the non-aggravated doshas is considered as the correct quantity.
- Administering the pratimarsha nasya daily gives us the effect same as that of marsha nasya, but they are not the same.
- Thaila is the best sneha(unctuous substance) for the daily use as head is the main seat of kapha dosha.
Aacharya Sushruta: ( Su. Ch. 40/ 20 – 57)
Aacharya Sushruta has explained 2 major types of the nasyas which have 5 subtypes.
- Shirovirechana nasya
- Snehana nasya
The five folded classification is –
- Shirovirechana nasya
- Pratimarsha nasya
- Avapeeda nasya
- Predhamana nasya
Among these Nasya and Shirovirechana nasya are the two main and important ones. Pratimarsha nasya is a type of Nasya.
Avapeeda nasya and pradhamana nasya are the types of Shirovirechana nasya.
Indications Of The Snehana Nasya:
The sneha nasya is administered to make up the deficient oily matter in the head in cases like emptiness of the head(shoonya shirasa), to impart strength to neck, shoulders, chest(greeva-skandha-uraso bala jananartham), to improve the vision(dristi prasada jananartham).In conditions like the diseases of the head due to the vitiation of wind(vataja shiroroga), falling of teeth, hair of the scalp and beard(danta-kesha-smashru paata), ear ache(karna shoola), tinnitus(karna kshweda), defective vision(timira), hoarseness of the voice(swaropaghata), diseases of the nose(nasa roga), dryness of the mouth(aasya shosha), frozen shoulder(avabahuka), premature wrinkles-graying of the hairs(akaalaja vali-palita), disorders arising due to wind and fire(vatapittaja vikaras), diseases of the oral cavity(mukha rogas).
Unctous substance prepared by vata and pitta pacifying drugs.
Quantity of the medicines for Sneha nasya:
The dosage of the medicine should be decided after analyzing the strength of dosha, disease and the person.
Prathama maatra: 8 Bindus (first dose)
Dwiteeya maatra: Shukti ( 32 Bindu) (second dose)
Triteeya maatra: Paani shukti ( 68 Bindu) (third dose)
Indications For Shirovirechana Nasya:
Conditions of palate-throat-head due to the vitiation of kapha dosha(Taalu-kantha-shira effected by kapha dosha), anorexia(arochaka), heaviness of the head(shirogaurava), head ache(shira shoola), coryza(peenasa), hemicrania(ardhavabedhaka), worm infestation(krimi), coryza(pratishyaya), epilepsy(apasmara), loss of the smell sensation(gandha ajnana), diseases of the head due to kapha dosha)kaphaja shiroroga.
Unctous substance prepared by the shirovirechana drugs.
Quantity of medicines for shirovirechana nasya:
- Minimum dosage: 4 Bindu
- Medium dosage: 6 Bindu
- Maximum dosage: 8 Bindu
Time of administering Sneha nasya and shirovirechana nasya:
- These two types of nasyas should be administered during the annakala( before food).
- In kapha diseases they should be administered in the Morning(poorvahnna)
- In pitta diseases it should be administered in the Noon(madhyahnna)
- In vaata diseases it should be administered in the evening(aparahnna).
- Nasya should be performed when the sky is not covered with clouds.
- Person who is suitable for the nasya karma should be selected.
- Before starting the procedure the patient should clear his natural urges.
- The patient should be asked to clean his oral cavity with tooth twig and medicated smoking.
- His gala( neck), kapola(cheeks), lalata( forehead) should be gently massaged and fomented with the heated palms.
- Then patient should lie on his back with his arms and legs fully starched outwards, in a room which is free of breeze, sun and dust particles.
- The head should be slightly extended. Eyes should be covered with a clean cotton cloth.
- The medicine should be taken in a silver or golden or copper or mud container and heated by keeping it over the hot water.
- The tip of the nose is slightly lifted with the left pradeshini finger and the Luke warm oil is instilled into the nostril with the right hand. Here the medicine should be taken in a shukti or cotton swab in order to get the continuous flow while instilling. The care should be taken not to spill the oil into the eyes.
- While instilling the medicine the patient should not laugh, shake, talk, sneeze or get angry. These actions prevent the oil from reaching to the desired places and cause cough,coryza( pratishyaya), diseases of the head(shiroriga), diseases of the eyes(nerta roga).
Post Operative Procedures:
- The patient should spit out the medicine which has reached the throat without swallowing it, otherwise it may aggravate the kapha dosha.
- Immediately after the instillation of the medicine into the nostrils, patient’s neck and cheeks should be gently fomented and the medicated smoke should be administered.
- After the completion of the procedure a anabhishyandi(food which does not generate kapha) food should be given to the patient
- The patient should avoid the exposure to dust, smoke, sun, anger, and he should not take alcohol(madya), liquids, head bath, traveling(atiyaana), anger(krodha).
Nasya yoga( samyak lakshana) of snehana nasya:
Lightness of the head(shirolaghava), timely sleeping and waking up without any discomforts( sukha swapna prabodhana), alleviation of the disease(vikaropashamana), clarity of the sense organs(indriya shuddhi), happy feeling of the mind(manahsukha).
Atiyoga symptoms of snehana nasya(effects of excess application):
Excess secretion of the kapha(Kapha praseka), heaviness in the head(shirogurutwa), dullness of the sense organs(indriya vibhrama), excess oiliness of the head.
Drying treatments should be done. (rooksha upachaara)
Ayoga symptoms of snehana nasya( effects of deficient application):
(Vaata derangement, dryness of the sense organs, non-alleviation of the diseases(roga ashanty).
Repeat the nasya karma.
Samyak yoga of vairechanika nasya(effects of proper application):
Lightness of the head(shirolaghava), clarity of the channels(srotasam shuddhi), alleviation of the disease(vyadhi shanty), clarity of mind and sense organs(chitta and indriya prasada).
After the nasya samyak yoga, a sneha nasya with ghee should be administered.
Ayoga symptoms of vairechanika nasya(effects of deficient application)
Itching(kandu),coated feeling in the head( upadeha), heaviness(guruta), excessive secretion of kapha(kapha samsrava).
Kapha shamaka treatment.
Atiyoga symptoms of vairechanaika nasya(effects of excessive application)
Expulsion of the brain matter(mastulugagamanam), wind aggravation(vatavriddhi), dullness of the sense organs(indriya vibhrama), emptiness of the head(shira shoonyata).
Vata shamaka treatment.
- Nasya karma can be administered with a gap of 1day, 2days, 7days, or 21days.
- In the patient of wind aggravation (vata rogi) it can be administered twice in a day.
Indications for Avapeeda nasya karma:
- In the disorders of head due to the vitiation of kapha dosha and meda dhatu, a person who is unconscious due to snake bite.
- In these cases any one of the shirovirechana drug is crushed and the juice is squeezed into the nostril and follow the other procedures of virechana nasya karma.
- In case of weak person(kheena purusha) and raktapitta rogi the drugs like sugar(sharkara), sugar cane juice(ikshurasa), milk, ghee and extract of meat(mamsa rasa) are used for the avapeeda nasya.
- In case of emaciated(Krisha), weak(durbala),timid( bheeru), delicate(sukumara), lady(stree), the unctuous substance processed with shirovirechana drugs or the paste(kalka) of the shirovirechana drug are used for the avapeeda nasya.
Indication for Pradhamana nasya:
In cases of derangement of the mind(chetana vikriti), worm infestation(krimi), poisoning(visha peedita).
In these conditions one of the shirovirechana drug is powdered and sprayed into the nasal orifice.
Contraindications For The Nasya Karma:
One who has just taken his meals(bhuktavan), fasting(langhana), acute coryza(taruna pratishyaya), pregnant(garbhini), one who has taken unctuous substance-water- alcohol-or any other liquids(peeta sneha-udaka-madya-drava), indigestion(ajeerni), after vasti(dattabasti), one who is angry(kruddha), gara visha, Thirsty( trisha), one who is suffering with grief(shokabhibhoota), tierd(shranta), young(baalaka), old(vriddha), one who has suppressed natural urges(vegaavarodhita), who has taken head bath(shira snata) or one who wants to have bath, amennohrea(anaartava), when the sky is covered with clouds(meghaacchanna aakaasha). These conditions are contraindicated for dhooma pana also.
Complications Of Nasya Karma (Nasya Vyapad)
Instilling the nasya drug in under or over dose, in very hot in very cold temperature, by hyper extending the head, sneezing, shaking or administering the nasya in the contraindicated conditions will lead to conditions due to increased or decreased doshas, thirst(trishna), belchings(udgaara) etc complications.
Aachaarya Sushruta has classified the complications into 2 types.
- Doshotklesha janita
- Doshakshaya janita.
Their treatments should be done accordingly.
In doshotklesha janita complications shamana and shodhana treatments should be done.
In doshakshaya janita complications brihmana treatments should be done.
Sushruta explains 14 times to administer the pratimarsha nasya.
- 1. Praathkaala or talpothita(after getting up in the morning)
- Pratimarsha nasya administered in this time helps in cleaning the mala (sticky secretion) from the nasa srotas which is collected in the night and also causes the cheer full state of the face( mukha prasannata).
- Prakshaalita danta(after brushing teeth)
- Leads to strong teeth(danta dridhata) and sweet odour of the mouth(vadana saugandhya).
- Grihaannirgacchata(before going out of the house)
- Keeps the nasa srotas moist and hence protects the body from dust and smoke.
- Vyayamante(after exercise)
- Vyavaayante(after sexual intercourse)
- Adhwagamanante(after a long walk)
- Helps in reducing the tiered ness.
- Mootra vegante(after urination)
- Adhovatante(after defication)
- Helps in reducing the heaviness of the vision(drishti gurutwa).
- Kavalante((after gargling)
- Anjanaante(after the application of collyrium)
- It helps to invigorate the eye sight(drishti prasadana).
- Bhuktavata(after eating food)
- Leads to clarity of the channels(srotoshuddhi) and lightness of the body(laghuta).
- Charditavata(after vomiting)
- Will create the urge to eat food by clearing the kapha sticking to the srotas(channels).
- Divaswapnothitena(after getting up from day sleep)
- Helps in removing sleepy feeling(nidra shesha), heaviness(gaurava), filthy accumulations in nose,etc(mala), and hence creates concentrated state of mind(chittaikagrata).
- Person will have sukha nidra and prabodhana(helps in getting a good sleep and easy awakening).
Quantity of Pratimarsha nasya drug:
The quantity of the drug which being lightly snuffed in, reaches down into the oral cavity is deemed adequate for a dose of the Pratimarsha nasya karma.
General benefits of the pratimarsha nasya:
Cures the conditions peculiar to the supra clavicular regions of the body, causes clarity of the sense organs, imparts sweet aroma to the oral cavity.
Also helps in the prevention of premature wrinkles(valee), premature graying of hairs(palita), hair fall(khaalitya), blackish ness of the facial skin(vyanga).
Provides strength to the jaw-teeth-head-neck-trika-arms- chest(hanu, danta, shira, greeva, trika, baahu, uras).
The unctuous substance used for nasya according to the doshas:
- In savaata kapha(conditions arising due to the combination of vata and kapha) – Thaila is used.
- In kevala vata(conditions due to only vaata) – Vasaa is used.
- In conditions due to pitta –- Ghee (sarpi) is used.
- In savaata pitta(conditions arising due to the combination of vaata and pitta)—Majja is used.
Aacharya Charaka explains about the drugs used for the purpose of shirovirechana and their benefits in the 2nd chapter of the sootra sthana.
Drugs use full in shirovirechana:
Apaamaarga beeja, pippali, mareecha, vidanga, shigru, sarshapa, tumburu, ajaaji, ajagandha, peelu, ela, harenuka, prutweeka, surasa, shweta, kutheraka, phaninjaka, shireesha beeja, lashuna, haridra, lavana dwaya, jyotishmati, naagara are used for the shirovirechana or nasya karma.
These drugs are used for shirovirechana in conditions like heavy ness of the head(shirogaurava), headache(shira shoola), rhinitis(peenasa), hemicrania(ardhaavabedhaka), worm infestation of head(shirogata krimi), epilepsy(apasmara), derangement of smell sensation(ghraana naasha), fainting(pramohaka).
(Ref : Cha. Su. 2/3,4,5,6)
Aacharya Charaka explains about the time and its benefits in dinacharya chapter.
Ref: Ch. Su. 5/56
Every year one should under go the nasya karma with Anu thailam in Praavrit(rainy season), Sharad(autumn) and Vasanta(spring season) ritus when the sky is free of clouds.
But in emergency conditions the nasya procedure can be done in other seasons also like in greeshma ritu it shoud be administered in the poorvahnna(morning), in sheeta ritu it should be done in the noon(aparahnna) and in varshaa ritu it should be done when the sky is not covered by cloudes.
- The healthy person who undergoes the nasya karma in suitable season with suitable drugs will never suffer from the impaired functions of eyes, nose, ears. The hairs of the scalp, beard will not fall and will not turn white or grey(kapila varna). The scalp hairs will start growing.
- Nasya karma performed in conditions like manya stambha(torticolis), shira shoola(head ache), ardita(facial paralysis), hanu sangraha(lock jaw), ardhavabedhaka(hemicrenia), peenasa(chronic coryza), shira kampa(head tremor) helps to cure those conditions.
- Anu thaila nasya administered in the suitable season nourishes the veins(siras), joints(sandhis), ligaments(snayu), tendons(kandara) of the head and makes them strong. The person’s face becomes cheerful and well developed (mukha prasannata). His voice will be melodious( upachita), snigdha, stable(sthira), grave(mahan). It imparts clarity( vaimalya )and strength(bala) to all sense organs. It prevents the diseases of supra clavicular region of the body. Even when the person is aging his supra clavicular region will not show any symptoms of aging.
In Indriya sthana aacharya mentions about 7types of nasya , classified according to the part of the plant used. They are:
- Phala nasya
- Patra nasya
- Moola nasya
- Kanda nasya
- Pushpa nasya
- Niryasa nasya
- Twak nasya
Contra indications for shirovirechana: (Cha. Si. 2/ 21)
Indigestion(Ajeerni), ater food intake(bhukta bhakta), after drinking the unctuous substance(peeta sneha), one who wants to drink alcohol(madya) and water, head bath(shirasnaata) or who wants to have head bath, one who is suffering from hunger, thirst and tiered ness, intoxication(matta), Fainted(moorchita), injuired by weapon or stick(shastra or danda hata), one who is tiered due to exercise, sexual intercourse and alcoholic drinks,acute fever( nava jwara), grief(shoka), one who is under gone virechana and anuvasana vasti, pregnant lady,acute coryza( nava pratishyaya), in contraindicated seasons and durdina.
Complications of administering nasya in the contraindicated conditions.
- Nasya in a person suffering from indigestion or who is just eaten his food makes the doshas to block the channels moving in upward direction and causes cough(kaasa), breathing difficulty(shwaasa), vomiting(chardi), coryza(pratishyaya).
- Nasya administered to a person who has taken the unctuous substance or a person who wants to drink alcohol or water will lead to excess secretions from the nose, oral cavity and eyes, defects of vision( timira), diseases of head(shiroroga).
- Nasya karma performed in a person who has taken head bath or if the person takes the head bath after nasya karma leades to coryza(pratishyaya).
- Nasya karma performed in a person who is suffering from hunger will lead to aggravation of wind(vaata prakopa).
- Nasya karma in a person suffering from thirst will lead to aggravation of the condition and causes dryness in the oral cavity.
- Nasya karma in a person who is affected with tiered ness, intoxicated (mada), fainted(moorcha) leads to the symptoms similar to that of aasthapana vasti doshas like mental disorder etc.
- Nasya karma in person who is injured by weapons or stick(danda) will aggravate the pain.
- Nasya karma in a person who is tired due to exercise, sexual intercourse and alcohol intake will lead to pain in head, shoulders, eyes and chest region.
- Nasya karma performed in a person who is suffering from acute fever (navajwara) and grief(shoka) makes the heat to circulate through the nerves of the eye( netra naadi) and causes defects of vision(timira) and aggravates the fever.
- Nasya karma in a person who has undergone a purgation(virechana karma) destroys the sense organs due to the vitiation of the wind.
- Nasya karma performed in a person who has under gone anuvasana vasti leads to aggravation of the kapha and causes heaviness of the head, itching, worm infestation of the head.
- Nasya karma in a pregnant woman will block the fetus. The child will suffer from conditions like one eyed(kaanaha), hump backed(kuni), paralysis, peeta sarpi(one who crawls on his back).
- The nasya karma performed in acute coryza(navapratishyaya) causes the disorders of that particular channel(srotus).
- Nasya administered in improper season and on a bad day causes foetid nostrils(pooti nasya roga) and other diseases of the head(shirorogas) due to the effect of cold, heat etc of that particular season.
Indications for shirovirechana:
- Disorders of the head and teeth
- stiffness of the nape region(manya stambha)
- stiffness of throat and jaw(gala and hanu graham)
- disorders of cornea (shukra roga)
- defects of vision(timira)
- diseases of eye lids(vartma roga)
- blackish discoloration of facial skin(vyanga)
- disorders of neck- shoulders- scapular region(amsa)- oral cavity- nose- ears- eyes- head
- facial paralysis
- convulsive disorder(apataanaka)
- tingling sensation of teeth(danta harsha)
- looseness of teeth(danta chaala)
- redness of eyes(akshi raaji)
- hoarseness of voice(swarabedha)
- obstructed speech(vaakgraha)
- loss of speech(krathana )etc diseases of the supra clavicle region of the body and chronic vaata vikaras. In these conditions aacharya says the shirovirechana is the best treatment as it enters the head and expels only the vitiated doshas from the head.
References Of Panchakarma In Samhitas:
- In Apaamarga tanduleeya chapter aacharya Charaka says that the vaidya should perform snehana swedana followed by panchakarma when the doshas are in highly aggravated condition.
- “taanyupasthita doshanaam sneha swedopapaadanai Panchakarmani kurveeta maatra kaalav vicharayeth”( Ref: Ch. Su. 2/ 15)
- The diseases of the asthi dhaatu should be treated with panchakarma and medications.
- “asthyshrayaanaam vyadheenaam pancha karmaani bheshajam”( Ref: 28/ 27)
- One of the quality of pranaabhisara vaidya is having thorough knowledge about shirovirechna etc panchakarma aushadha ganas( knowledge about the groups of drugs used in pancha karma)
- “ shirovirechanaadeshcha pancha karmaashrayasya aushadha ganasya….”(Ref: 29/7)
- In siddhi sthaana the name of the 2nd chapter itself is panchakarmeeya siddhi chapter. Here he gives us a detailed explanation of indications and contraindications for panchakarma.
- One of the deciple of aacharya punarvasu aatreya questions that is there any disease which does not respond to the panchakarma procedures?
- Then Punarvasu aatreya replies that Urusthambha is one disease which does not respond to the pancha karma.(Ref: Ch. Chi. 27/ 5)
- In the first chapter of the Siddhi sthana aacharya explains in detail about the Panchakarmas to his deciples.( Ref: Ch. Si. 1/ 3)
- Aacharya Sushruta while explaining the treatments for Madhumeha says to follow the certain set of the treatments to a madhumeha patient who has firm faith in medicines and desirous of existence and in whose case the curative efficacy of panchakarma has been baffled.
“panchakarmagunaateetam shraddhavantam jijeevishum” (Su. Chi. 13/ 19)
1. Aacharya Vagbhata while explaining the contra indications for sira vyadha (blood letting by venesection) says that it should not be performed on a person who has taken unctuous substance internally and one who has under gone pancha karma procedures.
“ snehapeete prayukteshu tatha panchasu karmasu” ( Ref: A. H. Su. 27/ 9)
2. Aacharya Vagbhata says the nasya karma should be performed after the vasti karma while doing the panchakarmas.
“ panchakarmaanyaacharato bastikarmottarakaalameeva” (Ref: A. S. Su 29/15)
In Sushruta samhita, Astanga sangraha and Astanga hridaya the word PANCHAKARMA is used in very few places. Where as in Charaka samhita it has been used in many occasions. | medical |
https://www.catchiscommunity.org/mental-health-providers | 2022-01-19T01:58:26 | s3://commoncrawl/crawl-data/CC-MAIN-2022-05/segments/1642320301217.83/warc/CC-MAIN-20220119003144-20220119033144-00519.warc.gz | 0.909075 | 169 | CC-MAIN-2022-05 | webtext-fineweb__CC-MAIN-2022-05__0__227468076 | en | Mental Health Providers
HELP IS AVAILABLE.
Whether you or your child are in a crisis or need help with daily challenges, the support of a mental health professional can make an enormous difference. Our community is full of wonderful social workers, psychiatrists, psychologists, and others who provide the resources, guidance, and tools we all need.
Here is a list of mental health providers who currently have openings and are taking on new clients:
Affiliates in Counseling
Courage to Connect
Glenview Counseling Group
Indigo Therapy Group
The Josselyn Center
North Suburban Center for Anxiety
Simply Bee Counseling
Youth Services of Glenview/Northbrook
Our goal is to keep this list updated, but please understand that availability may change suddenly. | medical |
http://www.vivomed.com/en/Push-Braces-Ortho-Thumb-Brace-CMC/m-7917.aspx | 2015-07-04T09:13:51 | s3://commoncrawl/crawl-data/CC-MAIN-2015-27/segments/1435375096579.89/warc/CC-MAIN-20150627031816-00054-ip-10-179-60-89.ec2.internal.warc.gz | 0.919824 | 1,092 | CC-MAIN-2015-27 | webtext-fineweb__CC-MAIN-2015-27__0__9260053 | en | |Home PageThumb Support|
Push Braces Ortho Thumb Brace CMC - to treat thumb osteoarthritis pain $83.76
The Push CMC thumb brace has been designed and developed by Push Braces in conjunction with eminent hand therapists Judy Colditz and Nettie Koekebakker.
This brace is now well accepted by many medical professionals as the best brace on the market for people who suffer from osteoarthritis of the CMC joint of their thumb.
CMC-1 osteoarthritis (thumb osteoarthritis of CMC joint) is a common thumb disorder. It is a type of ‘wear and tear’ of the articular cartilage, affecting in particular people between 40 and 60 years of age.The Push CMC is a slim and compact product. The brace can be used in the water. Hygiene is important around the hand. Therefore the synthetic material is antibacterial and the brace can be washed in a washing machine at 40°.
The Push CMC was especially developed for application with the following indications:
• CMC-1 osteoarthritis
• Postoperatively after arthroplasty of the CMC-1 joint
• Instability of the CMC-1 joint
In European countries, incidence rates vary between 16% and 25%. This means that one in every 4 to 5 people suffers from CMC arthritis.
Arthritis of the basal joint of the thumb, combined with a weakening of the ligaments, results in functional instability. This typically causes symptoms such as thumb pain, reduced hand function, weakness and stiffness. The thumb is responsible for an estimated 40% of all hand functions, so arthritis of the CMC joint may result in disabling restrictions of the hand.
Push has now introduced the ortho thumb brace CMC, or Push CMC for short. This new concept differs from standard solutions. The Push CMC stabilises the basal joint of the thumb and places the thumb’s metacarpal in a functional position. This creates a so-called ‘thumb arch’, which remains stable during activities of the hand and ensures proper gripping. It relieves the pain when the thumb is under stress. This method of stabilising leaves nearby joints, including the wrist, free. The aim is to achieve the best possible hand function.
The Push CMC thumb brace consists of a cylindrical section around the ball of the thumb and a fixed connection running along the palm to the outside of the hand. This can be closed at the back of the hand with two non-elastic bands. The cylindrical section consists of two components: an aluminium strip and a transparent, flexible, synthetic part. The aluminium strip can be shaped and individually adapted for maximum stabilization of the base of the thumb. The selected materials and rounded edges guarantee maximum comfort. The simple closing system enables patients to fit the brace themselves without any effort.
Please see the link below to a new article published in 2015 concerning the study entitled “Stabilization effectiveness and functionality of different thumb orthoses in female patients with first carpometacarpal joint osteoarthritis”, which was carried out by Nina Hamann et.al.
This article has recently been published in Clinical Biomechanics. In the article, three thumb orthoses were investigated in addition to the Push CMC. The study examined the stabilising capacity of the orthoses on the CMC joint and the MCP joint and the resulting effect of wearing the various orthoses on the function of the hand.
There are 36 reviews with an average rating of 4.77
Anonymous from United KingdomOwner30 April 2015 09:21
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https://nwtravelmag.com/author/the-health-benefits-of-panax/ | 2021-09-20T13:28:10 | s3://commoncrawl/crawl-data/CC-MAIN-2021-39/segments/1631780057039.7/warc/CC-MAIN-20210920131052-20210920161052-00237.warc.gz | 0.941197 | 728 | CC-MAIN-2021-39 | webtext-fineweb__CC-MAIN-2021-39__0__118731845 | en | The Health Benefits of Panax
We may never know when man first experienced erectile dysfunction, but we know that there has been a natural treatment for it originating from China and Korea used for thousands of years.
There are different kinds of ginseng which can be classified as red, white, or fresh. This classification is based on how long the period is before it is harvested. Four years pertains to fresh ginseng, between four to six years for white ginseng, and six years and above for red ginseng.
Another classification of ginseng is based on where its origins are located. American ginseng is known as Panax quinquefolius, while the ginseng mentioned above that treats ED and originates in Asia is referred to as Panax ginseng.
Panax ginseng (also called the Korean or red ginseng) is a powerful plant whose roots can positively contribute to improving one’s sexual function and promoting longevity and good health.
Here is a list of some of the health benefits of Panax ginseng:
Erectile Dysfunction Treatment
As mentioned above, Panax for ED is one of the most popular health benefits that can be gained from the ginseng for men. It enhances one’s physical performance which thus increases sexual stamina. Moreover, Panax ginseng not only helps with the hardness and duration of one’s erection; it also improves one’s libido and overall satisfaction.
Panax ginseng contains an antioxidant that helps reduce inflammation and can be used on the skin of people suffering from eczema. This antioxidant also contributes to increasing the production of nitric oxide (NO). NO is an essential component in stimulating an erection as it dilates the blood vessels in the penile area, allowing sufficient blood flow for an erection.
Brain Function enhancer
One of the health benefits of Panax ginseng is improving brain functions. This includes one’s memory, mood, and behaviour. A study conducted for four weeks resulted in an enhanced mental health condition, mood, and social functioning.
Immune System booster
Research conducted on the benefits of Panax ginseng to the immune system has been mainly focused on cancer patients. Studies show that stomach cancer patients who took 5,400mg of ginseng daily have improved their immune functions. More so, their symptoms have been less recurring.
Increased Energy Level
One of the things that people who take Panax ginseng have are lower fatigue experiences because of lower oxidative stress, together with an increased level of energy production.
Lowered Blood Sugar
Whether it’s American or Asian, ginseng proves to positively impact blood glucose control for people with or without diabetes. It helps in improving the uptake of blood sugar, pancreatic cell function, and insulin production. Moreover, ginseng extracts were found to provide antioxidant protection, which reduces the free radicals in the cells of those who have diabetes.
To conclude, Panax ginseng has been traditionally used over the centuries as a holistic wellness supplement. It has been proven safe and effective for:
- treating impotence
- reducing stress
- treating diabetes
- improving cardiovascular health
- increasing energy
Although Panax ginseng is a safe, and a natural remedy for erectile dysfunction, it’s always best to consult your doctor about taking any treatment. He or she can assess whether a treatment is ideal for you, depending on your prior and existing overall health conditions. | medical |
https://www.opc.gob.ar/en/tag/opc-en/ | 2024-03-03T23:10:04 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947476399.55/warc/CC-MAIN-20240303210414-20240304000414-00007.warc.gz | 0.935668 | 307 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__8686981 | en | FISCAL IMPACT OF BILL ON ASSISTANCE AND COMPREHENSIVE HEALTH CARE DURING PREGNANCY AND EARLY CHILDHOOD (CD-54-2020)
The purpose of the National Law on Assistance and Comprehensive Health Care during Pregnancy and Early Childhood (Bill CD-54-2020) is to provide comprehensive care for the health and life of women, and other gender identities capable of gestation, and their children during the first years of life to reduce mortality and malnutrition, protect early bonds, physical and emotional development, comprehensive health, and prevent violence.
Based on the assessment carried out, it is estimated that the measures with fiscal impact for the national government would be those related to the expansion of family allowances policy (Sections 4, 5, 6, 7 and 10 of the Bill), training of personnel involved in the care of pregnancy and early childhood (Section 17) and the provision of medical tests and treatments for pregnant persons at risk of thrombophilia (Section 23).
The cost of the expansion of family allowances is estimated at AR$5.13 billion. For its part, it has not been possible to estimate the cost of personnel training since information on the duration and modalities, target population and personnel in charge of providing the training is required. Finally, in relation with the care for pregnant persons with high-risk pregnancy due to thrombophilia presumption, a fiscal cost of AR$381 million per 1,000 pregnant persons is estimated. | medical |
http://ar.umncrc.org/2014/research/institute-for-health-policy-and-innovation/ | 2018-08-21T02:45:23 | s3://commoncrawl/crawl-data/CC-MAIN-2018-34/segments/1534221217909.77/warc/CC-MAIN-20180821014427-20180821034427-00153.warc.gz | 0.947055 | 1,962 | CC-MAIN-2018-34 | webtext-fineweb__CC-MAIN-2018-34__0__96206928 | en | Using Collaboration to Accelerate Evidence for Maximum Impact
The Institute for Healthcare Policy and Innovation (IHPI) brings great minds together at the NCRC to address healthcare’s biggest challenges. At stake is nothing less than the future of healthcare–its effectiveness, accessibility, value, affordability, quality and safety.
The University of Michigan has been a leader in health services research for decades. Now, as our nation and our state tackle healthcare reform, it’s more important than ever to create novel solutions that will improve the nation’s healthcare system. Over 400 IHPI investigators from U-M’s top-ranked schools of medicine, nursing, public health, engineering, social work, law, business, and public policy, among others, as well as members of affiliated local research groups, are collaborating to generate the evidence-based research policymakers need to make meaningful change.
IHPI members aren’t just thinking about healthcare policy – they are working to improve conditions “on the ground.” Central to their mission is making a difference in communities, focusing especially on addressing disparities in healthcare access and quality in metropolitan Detroit and other Michigan communities.
Patient “prehabilitation” improves outcomes before surgery
Research conducted by U-M surgeons shows that among patients scheduled for major surgery, those who make even modest positive lifestyle changes prior to their procedure show impressive gains in how well they bounce back. A pre-surgery “boot camp” for patients is already in place within the U-M Health System to provide education, guidance and motivation for patients to quit smoking, lose weight, become more active, and reduce stress before major surgery.
Recently, thanks in part to additional statistical and data analysis support from a quality collaborative housed within IHPI, those U-M surgeons earned a $6.4 million grant to expand the program’s scale, rolling it out to about 12,500 patients in 40 hospitals statewide as the Michigan Surgical and Health Optimization Program (MSHOP). The team is led by Michael Englesbe, MD, an associate professor in the Department of Surgery, and co-principal investigators Darrell A. Campbell Jr., MD, UMHS Chief Medical Officer, and Stewart C. Wang, MD, PhD, a professor in the Department of Surgery, who pioneered a technique called analytic morphomics which is used in MSHOP’s risk assessment tool. Evidence gathered will measure not only the clinical relevance of “prehabilitation,” but its economic and social value as well. Read more about the program at www.uofmhealth.org/news.
Insurance reform: from NCRC to Capitol Hill
The history of healthcare is marked by an interesting paradox. Despite countless innovations with proven clinical benefits, such as immunizations, cancer screenings and preventative care measures, evidence indicates that Americans consistently underutilize these high-value services. For over a decade, U-M health service researchers led by Mark Fendrick, MD, have been working to unravel this mystery, and have devised a novel, yet remarkably intuitive response to it: Value-Based Insurance Design, or V-BID.
Fendrick, a professor in the Department of Internal Medicine and Department of Health Management and Policy in the School of Public Health, directs the U-M Center for Value-Based Insurance Design, located within IHPI’s NCRC space, which studies and promotes the V-BID approach. V-BID is an alternative to the traditional “one-size fits all” approach to insurance that requires the consumer to pay the same out of pocket cost for every diagnostic tool, procedure, or drug, regardless of its proven benefit.
V-BID replaces the one-size-fits-all model with the concept of clinical nuance, which acknowledges that 1) not all services, procedures, tests and drugs are of equal value, and 2) the benefits of a specific clinical action vary based on who receives it, who performs it and where it takes place. In the V-BID model, patients face low or no cost barriers for high-value services (those with proven clinical benefit); for low-value services (those for which clinical evidence is weak and/or indicative of potential harm), the opposite is true.
Fendrick’s team has an ever-growing body of compelling evidence that V-BID is a major improvement in health insurance, and it’s no surprise that it is one of the few components of healthcare reform that has gained widespread and bipartisan support. In July, legislation was introduced on Capitol Hill paving the way for the Centers for Medicare and Medicaid to test the V-BID concept through the establishment of a regional demonstration program for high-quality Medicare Advantage plans to use V-BID in their insurance coverage. Learn more at www.sph.umich.edu/vbidcenter/.
“Big Data” a big opportunity for IHPI-affiliated center
While Michigan has long been a leading source of health services research, IHPI members are finding new ways to do more with the data they gather and analyze. From day one, the visionaries behind IHPI recognized that harnessing the power of Big Data would be critical to advancing members’ research objectives, and that to do so would require purposeful coordination across the many schools and research groups.
In an $8.5 million federal research contract awarded this year to U-M, the University of Michigan Kidney Epidemiology and Cost Center (UM-KECC), an IHPI-affiliated program, has been selected to serve as the coordinating center for the United States Renal Data System (USRDS).
The USRDS is a national data system that collects, analyzes and distributes information about patients with chronic kidney disease and end-stage renal disease. As a coordinating center, the UM-KECC will collaborate with the National Institutes of Health and the Centers for Medicare and Medicaid Services to provide clinical, biostatistical, epidemiological, data management and analytical expertise to maintain and update the existing USRDS database.
The USRDS project includes a multidisciplinary team of 21 investigators in IHPI from the Medical School, the School of Public Health, the Frankel Cardiovascular Center, and the School of Pharmacy, as well as subcontractors from Arbor Research Collaborative for Health (an IHPI partner) and the University of California-Irvine. Learn more at www.uofmhealth.org/news.
IHPI by the Numbers
IHPI is a centerpiece of the NCRC portfolio, and expectations have been high from the start. So far, the institute is on a fast track to exceed those expectations.
It starts with asking the right questions, including those that are also vexing legislators struggling to craft better policies. It also includes using data to track their own progress. As the following metrics illustrate, IHPI is making an ever greater contribution to helping the NCRC realize its vision of becoming “a world of fast-paced scientific discovery that ignites improvements to humanity’s health and well-being.”
The NCRC was created to make it easier to come together to solve complex problems. IHPI is taking full advantage of the opportunity, and their unique platform is already reaping benefits. Member faculty and young investigators tell us they’re partnering with more people, from more diverse backgrounds than ever before, within the NCRC physical space, on campus, and across the nation.
IHPI’s member roster continues to grow as they take on the most pressing issues in healthcare with some of the most far-reaching and unique collaborations ever attempted in the field:
IHPI currently occupies approximately 77,000 net square feet of usable space. With IHPI’s allocated NCRC footprint near capacity, the Institute is looking for creative ways to configure space to make room for everyone looking to collaborate here. New collaboration spaces are near completion. These spaces, which will become available for use in 2015, will add 11,000 more square feet to the IHPI footprint.
Is the IHPI model paying off? By one important metric, it certainly is. In fiscal year 2013, $82.6 million in external funding was expended for health services research led by IHPI members.
Another key measure of success for academics is being published in a prominent scholarly journal or cited in a well-known national publication. To measure success, IHPI leadership first developed a set of parameters to determine which publications to track, and then selected an elite subset of publications based on one of two criteria: 1) the publication is regarded as a major journal in the field, or 2) the publication has a two-year impact factor rating of 10 or more, such as the Journal of the American Medical Association or the New England Journal of Medicine.
As IHPI Director John Ayanian, MD, MPP, Alice Hamilton Collegiate Professor of Medicine, notes, “It’s been thrilling to see the camaraderie developing here, and the progress we’ve made in such a short time. Connections are being made between investigators who might not otherwise have even met. Existing projects are benefitting from additional support and momentum, and new initiatives are launching almost every day. The IHPI is off to a terrific start.”
For more information visit www.ihpi.umich.edu. | medical |
https://www.goizuetabeyond.com/story/when-family-medicine-becomes-lifesaving-work/ | 2019-10-21T17:48:59 | s3://commoncrawl/crawl-data/CC-MAIN-2019-43/segments/1570987781397.63/warc/CC-MAIN-20191021171509-20191021195009-00171.warc.gz | 0.975159 | 774 | CC-MAIN-2019-43 | webtext-fineweb__CC-MAIN-2019-43__0__48710123 | en | “Goizueta gave me the confidence and creativity to think about things differently — to ask, ‘Why not?’”
After her undergraduate studies at Williams College, Lowell initially worked as a curator in New York at a gallery. “I hated it. I wanted to be useful in a more concrete way.”
Her decision to study family medicine led her to the University of Connecticut School of Medicine, where she earned her MD. During her residency in Lawrence, Massachusetts, Lowell began to understand the serious needs of underserved populations. “The community of Lawrence is about 90 percent Dominican immigrants, many of whom have very limited access to healthcare,” she explained.
Throughout her childhood, Lowell watched her mother — an attorney — do “good work for what she thought was right — helping those who couldn’t find help elsewhere.” Similarly, Lowell found herself drawn to helping the most underserved populations. During her time in Lawrence, Lowell became aware of the unmet needs of transgender people. She spent time at the Mazzoni Center in Philadelphia, which is exclusively devoted to LGBTQ health and well-being and transgender care. After completing her residency in 2013 and moving to Atlanta with her wife, Emily, Lowell realized she needed an MBA because “the field of medicine is run like a business in the U.S.”
While earning her MBA at Goizueta, she also treated patients, supervised residents at Emory and ran outpatient clinics. “My peers and classmates at Goizueta were amazing,” Lowell recalled. “Goizueta gave me the confidence and creativity to think about things differently — to ask, ‘Why not?’” That drive led Lowell to start an innovative transgender clinic in Atlanta to reach patients without access to affirming care, Queer Med.
“The help I provide — which is pretty basic — saves lives."
Although “Izzy has won awards and accolades for her work with the transgender community, Lowell dreams of a day when she’ll go out of business.“I hope that one day all of my patients will be able to go to their primary doctor and have insurance cover their medical care.”
Lowell noted that many of her patients could be treated by primary care doctors, but many in the medical profession claim to be unable to treat them. In reality,“hormone therapy is far more simple than, say, treating type 1 diabetes.” Lowell cited sobering suicide rates for members of the trans community — 41 percent have attempted suicide compared to 4.6 percent of the general public — and notes that among adolescents, the rates are “beyond unacceptable.”
“Kids and teens are a large part of my practice,” she said. “It’s not often as a primary care doctor that you get to save a life in such a concrete way. The help I provide — which is pretty basic — saves lives. For some teens, it’s ‘transition or die.’ That’s when parents seek me out. They might say, ‘I’m not fully on board with this. I just want them to live.’”
Lowell noted that during puberty, many teens feel “every ounce of hormone pulling them in the wrong direction. A lot of what I do is stopping puberty. If a trans woman grows up to be a 6-foot adult male-bodied person with a square face and jaw, the transition process is more difficult. Some people may choose that, but if she has the option to be 5 feet 10 with softer features, she may be much safer in today’s world.” | medical |
https://laserliponutrition.com/services-2/ | 2024-02-22T19:02:38 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947473824.13/warc/CC-MAIN-20240222161802-20240222191802-00113.warc.gz | 0.910708 | 1,307 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__19430606 | en | Welcome to our comprehensive services page, where we offer a range of transformative treatments tailored to enhance your well-being. With expertise in laser lipolysis, chiropractic care, and body contouring, we provide a holistic approach to help you achieve your desired results.
Nutritional Weight Loss And Wellness Packages
Embark on a transformative journey towards optimal health with our Nutritional Weight Loss and Wellness Packages. Each package is tailored to your unique needs, providing personalized nutrition plans that guarantee visible results, helping you shed inches and achieve your desired weight. But it doesn’t stop there – we go beyond the numbers, empowering you with the knowledge and tools to sustain your weight loss in the long run. Our expert team is dedicated to supporting you every step of the way, making your wellness goals attainable and ensuring a healthier, happier you.Our personalized nutrition plans are carefully crafted based on your unique needs, ensuring a balanced approach to achieve your weight loss goals while fostering healthy eating habits. Our expert team provides constant support and adjustments to the plan, helping you not only shed inches but also improve your overall well-being and energy levels. Beyond the program, you’ll have the knowledge and tools to sustain your newfound healthier lifestyle for a happier, more fulfilling life.
In our chiropractic care services, we leverage over 20 years of experience to address a variety of musculoskeletal conditions and promote optimal wellness. Our highly skilled chiropractors employ a range of techniques, including manual adjustments, spinal manipulations, and therapeutic modalities, to alleviate pain, improve mobility, and restore balance to your body. By focusing on the spine’s alignment and optimizing the body’s natural healing abilities, we strive to provide effective and long-lasting relief. Whether you are seeking relief from back pain, neck discomfort, joint issues, or overall wellness enhancement, our dedicated team will work closely with you to develop a personalized treatment plan tailored to your unique needs.
Red light Therapy and Body Contouring
Our laser lipo services utilize modern techniques and cutting-edge technology to effectively target and remove stubborn fat deposits, allowing you to contour your body and achieve a more sculpted appearance. Our experienced professionals combine their deep knowledge and skill with the latest advancements in laser technology to ensure precise and remarkable outcomes. By harnessing the power of laser energy, we can selectively dissolve and eliminate unwanted fat cells, promoting a smoother, more contoured physique. Rest assured that your safety and comfort are our top priorities, and we adhere to stringent safety protocols throughout the process.
When it comes to body contouring, we offer a comprehensive selection of innovative procedures designed to refine your figure and enhance your natural contours. Our team understands that each individual’s body is unique, which is why we provide a range of options to suit your specific goals and preferences. If you’re struggling to lose weight or you have been on the never ending yo yo diet- Laser Lipo and Nutrition is here to help. This will be the last time you’ll ever have to lose weight again. We pride ourselves in helping our clients create a new healthy lifestyle through nutritional counseling and customize a plan that works for you and your body. Are you looking for a quick, long-term, and healthy solution? Look no further than Laser Lipo and Nutrition. We offer the most effective weight loss programs all without surgery, needles, drugs, or downtime.
Our team of doctors and nutritional specialists have a perfect solution to fit your needs through cold laser light therapy, natural supplements, and nutritional support. Here at Laser Lipo and Nutrition, we are dedicated to helping you look and feel you’re absolute best. Call Today to schedule a free computerized body analysis. Our goal is to make a positive difference in the health of our patients but give you and teach you the tools to keep off the weight for good
Benefits of Red Light Therapy
Red light therapy is a treatment that uses low wavelength red light to reportedly improve your skin’s appearance, such as reducing wrinkles, scars, redness and acne. It’s also touted to treat other medical conditions such as wound healing and tissue repair; reduce pain and inflammation; improve psoriasis, rosacea and eczema; improve scars; improve sun-damaged skin; reduce stretch marks; reduce wrinkles, fine lines and age spots; and improve facial texture.
It’s important to note that while there is a lot of ongoing research on the effectiveness of red light therapy for all types of health uses, the full effectiveness of red light therapy has yet to be determined
Targeted areas in Red Light Therapy
• Upper/Lower Abs
• Upper/Lower Back
• Inner/Outer Thighs
• Face & Neck
• Weight Loss Anti-Aging
• Improving your Overall Health
• Body Slimming
• Cellulite Reduction
• Skin Tightening
• Collagen Growth
• Skin Cell Renewal
• Improved Circulation
There are NO Needles, NO Pain, NO Bruising, NO Downtime, NO Surgery.
Our Commitment to Satisfaction
At our esteemed clinic, we hold the firm belief that personalized care and unwavering attention to detail are paramount in delivering exceptional outcomes. We take the time to genuinely understand your individual concerns, aspirations, and expectations, recognizing that each person’s journey is distinctive. Our dedicated team is committed to creating a treatment experience that is exclusively tailored to your specific needs, crafting a customized plan that considers your unique circumstances, preferences, and goals.
From the moment you step through our doors, you can expect a warm and compassionate environment where you are the focus of our attention. We place great importance on actively listening to your needs, ensuring that we grasp the nuances of your situation and work collaboratively to develop an effective treatment strategy. Our experienced professionals possess an intricate understanding of the complexities of the human body, allowing us to formulate a comprehensive plan that addresses your concerns with precision and expertise.
We invite you to explore our comprehensive services and discover how we can help you transform your body and elevate your overall well-being. Take the first step towards a healthier, more confident you by scheduling a consultation with our experienced team. Together, we will embark on a transformative journey, unlocking your body’s full potential and empowering you to embrace a healthier, happier life. ! | medical |
https://azm.org/truth-about-israel-north-africa | 2023-01-27T02:32:39 | s3://commoncrawl/crawl-data/CC-MAIN-2023-06/segments/1674764494852.95/warc/CC-MAIN-20230127001911-20230127031911-00728.warc.gz | 0.951349 | 193 | CC-MAIN-2023-06 | webtext-fineweb__CC-MAIN-2023-06__0__116449089 | en | Truth About Israel
An AZM Educational Campaign
In many areas of Africa, health facilities are inadequate. There are severe shortages of supplies, equipment and trained personnel. Furthermore, many people suffer from various degrees of blindness due to cataracts, malnutrition, trauma and infections that aren’t properly treated.
Since 1960, Israeli ophthalmology specialists, in cooperation and in consultation with local authorities, have been visiting Africa to help those who suffer from eye disease. Over the years, Israeli eye clinics have cured and restored sight for thousands of people.
These eye clinics were sponsored by the Israeli Foreign Ministry’s Center of International Cooperation, known by its Hebrew acronym, MASHAV. Launched in 1958, MASHAV’s mission is to share with the rest of the developing world the know-how and technologies which provided the basis for Israel’s own development. It aims to promote sustainable development and social equity. | medical |
https://watchmegrowtherapy.com/therapy-services.html | 2023-12-04T17:06:15 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679100531.77/warc/CC-MAIN-20231204151108-20231204181108-00310.warc.gz | 0.944961 | 1,254 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__295979295 | en | Occupational therapists are trained to help children succeed in activities of daily living in the home, school, and community. They are also trained to help children organize and interpret sensory information from the environment in an appropriate manner.
We will work with your child so that he/she can participate in the areas of bathing, grooming, dressing, feeding and playing.
Our occupational therapists will assist your child in learning how to develop fine motor skills to successfully master basic living tasks, such as: writing with a pencil (pencil grip), tying shoes, using scissors, zippering and buttoning buttons.
If your child has difficulty with visual perception and eye control, he or she will be treated by our occupational therapists to be able to recognize objects in order, to make adjustments regarding size and spatial relationships and to have the ability to use both eyes in a coordinated manner.
All of the sensory systems including sight, touch, taste, smell, hearing and even body movement and position can all affect child's development. If your child has any sensory deficits, our team will use age-appropriate activities in order to help your child regulate sensory input.
Eye-hand coordination, body awareness, balance, gross motor coordination mobility, flexibility and core strength are all crucial to your child's success and self-esteem, as they all collectively will allow your child to participate in and master age-appropriate physical skills and activities with their peers.
These skills allow for sensory information to be successfully understood by your child. Perceptual motor activities involve using the brain (cognitive skills) and (physical skills) simultaneously, like walking and talking at the same time.
Speech-language therapists are trained to help children effectively communicate their wants and needs to those around them. They are also trained to help with feeding and swallowing issues.
Children who have difficulty maintaining a heathy weight or are suffering from "failure to thrive," can benefit from treatment by our therapists. In this area, we work to increase your child's caloric intake and to expose your child to new varieties of food textures, tastes and temperatures. During feeding therapy, we also provide instruction and practice on sucking, chewing and swallowing. Oral aversion therapy can also be provided.
A variety of pediatric voice disorders can have profound effects on a child's life. If your child is experiencing changes in pitch, loudness and overall voice quality, they may benefit from voice therapy, which also includes treatment for resonance and fluency disorders.
Our speech and language therapists help children with both receptive (understanding, responding to and following directions) as well as expressive (using words or sign language to share thoughts and feelings with others).
If your child has difficulty hearing and differentiating sounds as well as sounding words out so that they may be understood by others, he/she should be evaluated for an articulation deficit or disorder.
During sessions with our speech and language therapist team, any difficulties with movement involving the mouth in order to speak, swallow Or eat will be addressed through strength training sessions, coordination practice and breathing therapy.
In children who suffer from childhood apraxia of speech (CAS), the brain has difficulty making plans for speech movement. If your child suffers from apraxia, our therapists will help create a therapy plan that focuses on practicing syllables, words and phrases in a repetitive and frequent manner
The Board-Certified music therapists who work with your child will use music interventions that are formed and shown effective by research evidence, music therapy theory and clinical practice. These therapeutic treatments include improvisation, songwriting, lyric analysis, music assisted relaxation and imagery, and developmental speech/language and cognitive music exercises. Music therapy also increases communication, socialization, and memory in children. Because music therapy bridges the gap between art and science, and the artistic nature of the therapy allows children to open up and explore their feelings.
May include both singing and instrument play using the child’s preferred music or music familiar to the child in order to address attention skills, language/speech skills, sensorimotor skills, and/or emotional skills.
Allows a child to explore the meaning, structure and lyrics of a song to allow opportunities to practice emotion identification, executive functioning skills, and encourage self-expression.
By combining these two fine arts, the child engages in a creative process to provide opportunities for emotional identification and self-expression, to facilitate and practice sustained attention skills.
Promotes relaxation and positive coping skills. This intervention can be used to decrease anxiety and stress.
Provides opportunities for creative self-expression, emotion identification, as well as reflection. This intervention also provides opportunities to explore decision making skills, can help increase self-esteem, and often is used to express the patient's medical journey and life experiences.
Unlike in regular music lessons, the ultimate goal is not mastering a new skill but rather providing the child with a meaningful distraction, a positive coping technique, and an outlet for expression all while increasing their self-confidence.
Watch Me Grow provides Habilitation, Respite Care, and Attendant Care for children and adults in their home and community. To be eligible for funding, families must be approved through Arizona Long Term Care Services (ALTCS)
This service is the children that need assistance with working on outcomes that are described in their Individual Service Plan.
This service provides short-term relief for the primary caregiver. This service can be provided any time of the day or evening that the caregiver requests for. Respite services are authorized by the Arizona Division of Developmental Disabilities (DDD). The maximum annual approval for respite is typically 600 hours.
This service is responsible for providing care to clients based on their current set of goals and level of functioning. It is used to increase independence in individuals and offer support services including improving communication, learning adaptive skills, independent living, and any other goals set by the support team. Habilitation may be used hourly.
8:00AM - 6:00PM
8:00AM - 6:00PM
8:00AM - 6:00PM
8:00AM - 6:00PM
8:00AM - 6:00PM | medical |
https://www.neswell.net/blosm | 2021-07-31T11:06:32 | s3://commoncrawl/crawl-data/CC-MAIN-2021-31/segments/1627046154089.6/warc/CC-MAIN-20210731105716-20210731135716-00290.warc.gz | 0.939173 | 1,504 | CC-MAIN-2021-31 | webtext-fineweb__CC-MAIN-2021-31__0__225685522 | en | Blosm™ is a scientifically validated CBD lubricant for woman who suffer from genital discomfort and looking for a natural water-based solution.
Painful sex is a growing unmet condition
Pain-related intimate conditions are common but neglected female health problems causing devastating effects on woman's quality of life. Its prevalence is tremendously high; Nevertheless, many woman do not report this pain.
2 in 5 women suffer discomfort or pain during sex.
2 in 10 women suffer from genital muscle contraction
Developed by woman for woman
Blosm™ is bringing a new standard for intimate wellbeing through unique and validated wellness products designed for women’s bodies by women’s experiences.
Behind the NI™
seal of validation
A science-based, patient- first approach to Cannabis products with state-of-the-art research, Assuring consistency of CBD-based products through a new and innovative standard of biological validation.
The NI™ (Neswell Inside) seal in Blosm means that this CBD product went through extensive research and found to be effective.
We Only Work With The Best
Gynecologist, specializing in vulvovaginal disorders and vulvodynia for 15 years.
“In a large proportion of patients who experience vulvar pain, the cause for the pain is not found, although a thorough evaluation is performed. It is assumed that the cause may be a defect in the nervous conduction system, which produces the feeling of pain and discomfort. When this is the case, there are ways to treat the pain. The problem arises when these complaints are answered with contempt or attributed to psychological "issues" or the patient's imagination. It should be acknowledged, that although we often do not find any physical sign, pain is a real sensation.
While vulvodynia for example is present in 10 -15% of women, those who experience pain during intercourse, whether by penetration (including inserting a tampon, for example) or as a result of any type of vaginal contact (not just sex, but also because of wearing of pants that are too tight, for example), already make up a wider proportion of the population. Up to 40 % of women suffer from pain during genital contact and about 20% of them describe the pain as unbearable and as preventing them from functioning sexually.
We hope the cannabis-based products will join our current therapeutic toolbox and may be used for treating vulvodynia and other pain syndromes in the future."
Prof. Ahinoam Lev-Sagie, MD
VP R&D at Neswell group, has 7 years of broad international experience in biotechnological, pharmaceutical and drug-device combination in the pharma industry and 3 years of experience in the cosmetic/OTC/wellness industry.
"More and more scientific evidence pinpoints on a relationship between cannabis and pain relief treatments, and women, who are exposed to these publications are constantly taking an interest in such remedies.
Unlike in the pharma industry, where a drug in development goes through preclinical and clinical phases prior to reaching the market, cannabis was long used by the global population before being tested in the lab, encouraging the industry to develop related products.
As not all CBD extracts are identical in their efficiency, we took the leads to match the best fitted CBD from full extract hemp that was proven to be efficacious in the lab into blosm”.
Full-spectrum US hemp
Blosm ™ incorporates scientifically validated American grown hemp extract that was proven in laboratory testing to be efficacious against pain-related markers.
Blosm™ is a science-based product, assures consistent therapeutic effect through a new and innovative standard of biological validation. The NI™ (Neswell Inside) seal in Blosm means that this CBD product went through extensive research and found to be effective.
100% naturally derived ingredients
All the ingredients in blosm are from a natural source
The irritating properties of blosm were evaluated in a study under the supervision of a dermatologist on a group of 50 volunteers, including 25 volunteers with sensitive skin. none of the volunteers reported any skin reaction or sensitivity to blosm.
Frequently asked questions
Is Blosm™ safe?
Blosm™ is a doctor-recommended product, contains 100% naturally derived ingredients and a preservative-free formulation, and not consider a hormonal treatment (estrogen-free).
In addition, the irritating properties of Blosm™ were evaluated in a study under the supervision of a dermatologist on a group of 50 volunteers, including 25 volunteers with sensitive skin. none of the volunteers reported any skin reaction or sensitivity to Blosm™.
How do I use Blosm™? Can I consume it orally?
Blosm™ is not for oral consumption and should only be applied topically on vaginal external openings. Apply 2-3 pumps on clean fingers and spread gently on your external intimate areas. Blosm™ can be used up to 5 times a day.
What does NI refer to?
Blosm™ is a science-based product, assures consistent therapeutic effect through a new and innovative standard of biological validation. The NI™ (Neswell Inside) seal in Blosm™means that this CBD product went through extensive research and was found to be effective against pain-related markers.
How is Blosm™ different from other lubricants?
Blosm™ is a unique development of Neswell Labs. It is a water-based intimate-care product for women who suffer from genital dryness, pain, and discomfort.
One of the most important facts in Blosm™ is that it incorporates scientifically validated hemp extracts that were proven in laboratory testing to be efficacious against pain-related markers.
How many times a day can / should I use Blosm™?
Blosm™ can be used up to 5 times a day, 2-3 pumps per usage.
Can I get high from using Blosm™?
Blosm™ contains a CBD-rich hemp extract. The psychoactive compound in cannabis is THC but it is only found in small traces in Blosm™. Therefore, you cannot get “high” by using the product.
Where can I purchase Blosm™?
At the moment you can receive Blosm™ only in specific clinics. Soon, it will be sold online.
I’m experiencing pain during intercourse. Can I use Blosm™?
Yes. blosm™ was developed by women scientists to answer the need of women to have a simple yet beneficial product for their intimate conditions including pain during intercourse.
What does Blosm™ contain?
Blosm™ is a CBD-based formula, enriched with hamamelis, chamomile, and aloe vera extracts for an enhanced soothing effect. The product is 100% naturally derived ingredients, preservative-free, and non-hormonal treatment (estrogen-free).
Is Blosm™ a natural product?
Blosm™ contains 100% naturally derived ingredients.
Does Blosm™ fit the vaginal pH?
Yes. Blosm™ was developed to match your vaginal pH to ensure optimal experience and results. | medical |
http://www.assis-tech.com/ | 2019-05-21T09:46:22 | s3://commoncrawl/crawl-data/CC-MAIN-2019-22/segments/1558232256314.25/warc/CC-MAIN-20190521082340-20190521104340-00012.warc.gz | 0.948764 | 511 | CC-MAIN-2019-22 | webtext-fineweb__CC-MAIN-2019-22__0__67514783 | en | It’s normal for men to see a decrease in T levels as they age. Unfortunately, low testosterone levels can cause a host of problems. Test boosters are the ideal way to solve these kinds of issues. Read on to learn more about the benefits these supplements can provide.
You’ll Have More Energy
A lot of people feel worn down and tired by the end of their workday. If you’re one of those people, and you’re looking for ways to get a boost of energy, you should look into taking testosterone. When your testosterone levels are higher, you’ll see a significant increase in your energy levels.
When you have more energy, you can accomplish more in your day-to-day life. You won’t be too tired to go to the gym or spend time with your family and friends. You’ll have enough energy to enjoy living your life.
You’ll Have More Productive Exercise Sessions
These supplements are especially popular with men that are trying to get into shape. Naturally increasing your testosterone levels will help you to have more effective workouts.
When your testosterone levels are higher, you’ll be able to increase your muscle mass. You’ll also be able to push your body further; you’ll be able to accomplish more in a single workout session. Taking a testosterone supplement will also make it easier for you to decrease your body fat.
You Can Boost Your Libido
It’s normal for men to see a decrease in their libido when they get older. What many men don’t know is that this libido decrease is usually linked to their lowered testosterone levels.
A lower sex drive can have a very negative impact on your life. In some cases, it can damage your romantic relationships. If you’re looking for ways to increase your sex drive, you should look at natural solutions. The right supplement should bring your sex drive back to where it used to be.
If you’re not satisfied with what you are accomplishing with your time at the gym, you may need an extra boost. An increase in testosterone should give you the push that you need.
Take a closer look at the many benefits offered by testosterone boosters. Look at what these supplements will be able to do for you. If you have a clearer understanding of the benefits testosterone supplements can provide, you’ll be able to decide whether or not these boosters are a good fit for you. | medical |
https://doctortornatore.com/how-food-affects-your-brain/ | 2024-02-25T17:55:50 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947474641.34/warc/CC-MAIN-20240225171204-20240225201204-00597.warc.gz | 0.959789 | 289 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__96754307 | en | One of the health practitioners I most trust to help my clients with their anxiety and depression is Kristen Allott, ND.
I have known Dr Allott, followed her work, and sent clients to her almost since I began my practice 15 years ago. I regularly use her suggestions to help my clients change their eating to reduce their anxiety.
Now she and Natasha Duarte have written a book so they knowledge she gives to her clients is available to anyone! Yay!
Fuel Your Brain, Not Your Anxiety: Stop the Cycle of Worry, Fatigue & Sugar Cravings with Simple Protein-Rich Foods is a well-written, easy to understand book that WILL help you improve your mental health.
The description of the brain and how food affects it makes it easier to make healthier choices for your mental health. I have changed my eating habits since I read this book for healthier sleep.
Among many other things you’ll learn:
- How our food choices contribute to anxiety, worry, and fatigue
- How a history of trauma affects how your brain responds to adrenaline
- Why moving makes us think better
- 30 second exercises to increase your energy
I am so excited that Kris and Natasha have created this book that will help so many people. You can save 20% by using the code FUEL21 during the month of February when you order their book through New Harbinger’s website at | medical |
https://www.cliniquechloe.com/en/product/3-face-v-beam/ | 2021-05-18T18:07:10 | s3://commoncrawl/crawl-data/CC-MAIN-2021-21/segments/1620243991288.0/warc/CC-MAIN-20210518160705-20210518190705-00269.warc.gz | 0.929963 | 162 | CC-MAIN-2021-21 | webtext-fineweb__CC-MAIN-2021-21__0__57882530 | en | ABOUT THIS PACKAGE
V-Beam is a vascular laser that targets red blood cells. It can treat any vascular lesion such as rosacea, dilated red vessels, active acne as well as ruby angiomas, stellar angiomas and port wine stains.
HOW IT WORKS
V-Beam is a laser whose waves are attracted by the reddish color of red blood cells, making it one of the most effective ways to reduce the redness and discomfort caused by rosacea.
We aim for more even skin, with no visible redness or blood vessels.
The V-Beam treatment is done by using different nozzles that will send laser waves specifically to areas of the skin affected by rosacea, commonly the cheeks, chin and nose. | medical |
http://drbillyflowers.com/about-us/what-is-chiropractic-.html | 2018-07-21T13:10:44 | s3://commoncrawl/crawl-data/CC-MAIN-2018-30/segments/1531676592579.77/warc/CC-MAIN-20180721125703-20180721145703-00297.warc.gz | 0.943712 | 313 | CC-MAIN-2018-30 | webtext-fineweb__CC-MAIN-2018-30__0__89943757 | en | The Alternative to Surgery and Drugs
Although Dr. Flowers' office is similar to other doctors' in appearance, the use of chiropractic for treatment of pain in shoulders, back, neck, arms and legs, for auto and sports injuries, muscle spasm, headache and a variety of other illnesses, is a very different approach from that of orthodox medicines. Chiropractic, through manipulation and treatment of the spine, can permanently relieve physical and physiological problems, which orthodox medicine treats with orthodox medicine treats with drugs and surgeries. Chiropractic is the modern medical alternative for health conscious people, although physical treatment has existed since ancient times. As a healing science, modern chiropractic has gained enormous public acceptance and acclaim. It is natural and painless treatment and produces a cost-effective, lasting result.
Vertebral Subluxation Complex
Chiropractic is concerned with the enhancement of human performance on every level. The basic principle of chiropractic is revealed through understanding the vertebral subluxation complex which is characterized by discrete alterations of one joint position or motion which, in turn, irritates nerves that control chemical balance, muscle tone, and range of motion. As each cell of the body receives nerve messages that originate directly or indirectly in the spine, it is imperative that alignment is correct. Uncorrected, it will result in too much or too little joint motion, nerve energy, and muscle activity. Inflammation and swelling as well biochemical and bioeletrical changes may also occur which contributes to joint degeneration. | medical |
https://www.starrybrooke-yoga.com/yoga-diabetes | 2020-09-24T12:33:07 | s3://commoncrawl/crawl-data/CC-MAIN-2020-40/segments/1600400217623.41/warc/CC-MAIN-20200924100829-20200924130829-00631.warc.gz | 0.929948 | 1,279 | CC-MAIN-2020-40 | webtext-fineweb__CC-MAIN-2020-40__0__278664845 | en | Yoga & Diabetes
This page is intended to provide insight and information on documented and potential benefits of movement, breath, and meditation inquiries for the management of diabetes and its complications. While the focus is specifically on diabetes I believe the benefits of yoga described here apply to the management of many chronic conditions and life situations, as yoga, in contrast to allopathic medicine, offers neither diagnosis nor cure but a set of tools to bring the individual to greater awareness and inner healing.
I hope this page reaches diabetics interested in yoga, yoga teachers and therapists interested in providing classes to diabetic populations, and physicians and researchers curious about the potential that yoga has to help patients monitor their conditions. The organization of the information and specific topics I've chosen to cover are rooted in more than 30 years of living with Type 1 diabetes, what I have gained from yoga practice and study, and, where possible, scientific resources and research into both the benefits of yoga and the complications of diabetes. Please note that before beginning any exercise program a diabetic patient should discuss the potential impact on blood glucose management and medications with an appropriate medical professional.
General wellness benefits of yoga
Yoga classes can provide community, confidence, a sense of personal empowerment, greater body awareness, flexibility, balance, stress relief, and strength. While not all forms of yoga are aerobic, as with many types of exercise, yoga can potentially increase insulin sensitivity. Two recent books describe these overall benefits of yoga and detail breathing techniques, poses, sequences, and special considerations for diabetic populations:
Other resources on general benefits of yoga practice:
Potential Benefits for diabetic complications affecting the enteric nervous system and vagus nerve
Fluctuations in blood sugar over time can damage the vagus nerve, which serves as the parasympathetic communication channel from the enteric nervous system to the central nervous system (CNS), and eventually lead to gastroparesis, a disorder in which the stomach takes too long to empty, causing a variety of symptoms, including increased susceptibility to bacterial infection, nausea, bloating, abdominal discomfort, and weight loss. Gastroparesis affects approximately 20% of Type 1 diabetes patients. Decreased respiratory sinus arrhythmia (RSA), an indication of decreased vagal tone, is also found in diabetes patients not (yet) affected by gastroparesis. This decrease in vagal tone results in less ability to balance the sympathetic nervous system (SNS), associated with the well-known "fight-flight-freeze" response, with the parasympathetic nervous system (PNS). Deep abdominal breathing, breath-linked movements, meditation, and yoga nidra, all tools offered in yoga, can potentially strengthen vagal tone and, together with improved glucose control, help reverse this complication.
**About Diabetes, gastroparesis, & the vagus nerve:
**General information about the vagus nerve:
**About yoga and its effects on the vagus nerve:
Potential benefits for other forms of diabetic neuropathy
It is estimated that 60-70% of diabetics are affected by nerve damage, or neuropathy. The causes can include metabolic factors, vascular factors (including damage to the blood vessels that carry oxygen to the nerves), autoimmune factors, or mechanical injury to nerves (e.g. carpal tunnel syndrome). The most common type, peripheral neuropathy, is characterized by pain or loss of feeling in the toes, feet, legs, hands, and arms, or, alternatively, extreme sensitivity to even light touch. Lack of sensation in the feet places sufferers at risk for infection, as small abrasions may go unnoticed and spread to the bone, leading to amputation. Medications, including opioids, are sometimes prescribed to combat the pain. Yoga has been shown in studies to improve medial nerve conduction velocity in practicioners with peripheral neuropathy and improved grip strength and reduced pain in sufferers from carpal tunnel syndrome. It is my own personal belief that slow deliberate movements increasing awareness of breath and body could help strengthen damaged neural pathways or create new ones.
**About Diabetetic neuropathy:
**Review of studies on the therapeutic value of yoga:
**Reduction in oxidative stress in patients with Type 2 Diabetes:
Potential benefits for limited joint mobility
According to recently published literature review, "Musculoskeletal disorders such as Achilles tendon pathology, trigger finger, Dupuytren, limited joint mobility syndrome (LJMS), carpal tunnel syndrome, frozen shoulder and plantar fasciitis have been found to occur more often in subjects with diabetes compared to those without diabetes." Less attention has been paid to these complications, as they are less connected with mortality than complications such as heart disease and micro/macro-vascular complications, even though they significantly impact quality of life and are correlated with other complications of diabetes. An accepted hypothesis is that, "the joint tissue damage in diabetes is caused by an excess of advanced glycation end products (AGEs) that form at a slow but constant rate, accumulating over time in the normal body. However, their formation is markedly accelerated in diabetes because of the increased availability of glucose. A key characteristic of reactive AGEs is the formation of covalent cross-links within collagen fibers, altering their structure and functionality." A carefully constructed yoga program focusing on breath and body awareness is not only an excellent tool for managing the pain of these conditions, but can potentially improve antioxidant status to reverse damage from reactive AGEs.
**About limited joint mobility in diabetes mellitus:
**About the potential of yoga to improve antioxidant status:
Potential benefits of yoga for diabetes-related trauma
Diabetes is related to trauma in at least three distinct ways: (1) Episodes of hypoglycemia and daily stress over the management of blood sugar can cause trauma; (2) Diabetics develop more complications after trauma than do non-diabetic groups; (3) Some studies have suggested a causal connection between trauma and later development of diabetes. For all of these reasons, trauma-sensitive yoga, with its emphasis on experiencing the present moment, making choices, taking effective action, and creating rhythms, can be very healing for diabetics also struggling with trauma.
**About diabetes and trauma: | medical |
http://focusingonlifegrp.blogspot.com/2016/06/the-unexpected-journey.html | 2017-04-29T19:31:55 | s3://commoncrawl/crawl-data/CC-MAIN-2017-17/segments/1492917123560.51/warc/CC-MAIN-20170423031203-00615-ip-10-145-167-34.ec2.internal.warc.gz | 0.987615 | 1,052 | CC-MAIN-2017-17 | webtext-fineweb__CC-MAIN-2017-17__0__84443033 | en | |Christian and me in 2009.|
When our first grandchild was born, we were understandably ecstatic! He was healthy and perfect and so we had no idea what was in store for him and for us all in the future. He met all the milestones – smiled, laughed, and interacted right on schedule – so we had no warning signs, at least for a while.
The initial concern was that he wasn’t talking as much as he should be for his age and there were other things that were concerning like not playing with toys in the usual way (lining up cars rather than zooming them around on the floor). There were a very limited number of foods that he would eat. Changes in routine were upsetting to him. These things and others led doctors to do testing and Christian was eventually diagnosed with an ASD (Autism Spectrum Disorder), specifically PDD-NOS (Pervasive Developmental Disorder Not Otherwise Specified). I was like a lot of people and assumed all kids with autism were non-communicative and non-interactive. Christian was happy, smiling and loving, and to us this meant the autism diagnosis had to be wrong.
|Ages 9 months, five and seven.|
However, after much research, we found out that ASDs range from mildly to profoundly disabling and that PDD-NOS is usually on the milder side. PDD-NOS is characterized by delays in the development of socialization and communication skills. These may include delays in using and understanding language, difficulty relating to people, unusual play with toys and other objects, and difficulty with changes in routine or surroundings.
With this diagnosis, he began receiving speech and occupational therapy at a local hospital and was later tested by the school district for inclusion in their special needs preschool which he began attending at age 4. He went from there to the elementary school, middle school and high school and we all learned as we went along. Being the one to help with homework every day, I had to learn the best ways to teach him. Being able to picture things helped him to understand them so my drawing skills (not much to speak of!) were tested.
|First day of second grade.|
As he moved from grade to grade, he was put into more mainstream classes. His challenge remained (and still remains) reading comprehension. Since reading is such a big part of all subjects in school, we worked extra hard to increase his vocabulary and comprehension.
Autism statistics from the U.S. Centers for Disease Control and Prevention (CDC) identify around 1 in 68 American children as on the autism spectrum – a ten-fold increase in prevalence in 40 years. Careful research shows that this increase is only partly explained by improved diagnosis and awareness. Studies also show that autism is four to five times more common among boys than girls. An estimated 1 out of 42 boys and 1 in 189 girls are diagnosed with autism in the United States. Autism appears to have its roots in very early brain development. However, the most obvious signs of autism and symptoms of autism tend to emerge between 2 and 3 years of age.
|Christian at age 6.|
But enough facts. If you want to know more about autism, there are plenty of resources out there. I’m here to talk about the feelings, how the feelings of joy are somewhat dimmed by the worry when you receive the diagnosis. But receiving the diagnosis meant he would qualify for services from admission to the special needs preschool program in our school district to speech and occupational therapies. And watching him gain new skills and become more social was so rewarding. And we all learned along the way. Although struggling with reading comprehension and vocabulary, he has an amazing memory which has helped him overcome these challenges. Like any typical boy, he loves sports, especially basketball. He has played in a community basketball league since he was seven and knows all the players on every NBA team. He’s warm and funny and loving.
I am thinking about all of this today as he finished his freshman year in high school last week. He has been in almost all mainstream classes this year with only a few accommodations given to him in his IEP (individual education plan) and finished with all A’s and B’s. I am so proud of him and how hard he has worked to get where he is today.
|First day of Freshman year -- age 14.|
I’m sure you’ve all heard the story called “Welcome to Holland” by Emily Perl Kingsley about raising a child with a disability. She likens it to planning a trip to Italy and ending up in Holland. “It’s not what you planned but if you spend your life mourning that you didn’t get to Italy, you may never be free to enjoy the special and very lovely things about Holland.”
Although this journey has not been what we planned or expected, it has been wonderful! We are very blessed to have this sweet boy in our lives and that he is doing so well. He will turn 15 next week and we couldn’t be prouder! | medical |
https://topbracelet.com/product/genesis-k-motion-tape-with-copper-infuzion-black-pre-cut-pack/ | 2017-10-19T05:43:31 | s3://commoncrawl/crawl-data/CC-MAIN-2017-43/segments/1508187823229.49/warc/CC-MAIN-20171019050401-20171019070401-00471.warc.gz | 0.902079 | 389 | CC-MAIN-2017-43 | webtext-fineweb__CC-MAIN-2017-43__0__13251218 | en | Genesis K-Motion Tape with Copper Infuzion- Black Pre-Cut Pack
- The only copper-infused kinesiology tape. Instead of wearing a copper bracelet, now you can apply it anywhere on the body with K-Motion!
- Copper provides anti-fungal and anti-bacterial properties for increased comfort and skin health as well as promoting more rapid healing.
- Synthetic / cotton hybrid fabric releases moisture quickly after showering or exercising
- Provides up to 5 days of continuous support and drug-free pain relief
- Each package contains 20 precut I-strips. Each strip is 2" x 10" - suitable for application on most areas of the body without requiring cutting
K-MotionTM with Copper InfuzionTM is an innovative kinesiology tape solution for treating & preventing common repetitive injuries such as wrist, forearm, elbow, shoulder, knee pain and more. K-MotionTM is the first tape of its kind with copper infused into a highly elastic synthetic/cotton hybrid material, and has proven highly effective for repetitive motion injuries. Applied correctly, it provides pain relief, increased support and added stability for injured or weakened muscles, delays fatigue and can ease joint soreness. All without sacrificing your comfort or freedom of movement. K-Motion with Copper Infuzion is very easy to apply, is anti-microbial, and can be worn for 3-5 days at a time, providing relief the entire time it is worn. For all common injuries including wrist, fingers, carpal tunnel, forearm, elbow, bicep, tricep, shoulder/rotator cuff, neck, lower back, quad, thigh,knee, hamstring, calf, ankle, Achilles Tendon and more.
- ASIN: B015M4XKE6
- Item model number: GENKMPC-Black
- Average Customer Review: Customer Reviews | medical |
https://biomedarts.com/the-use-of-natural-products-to-target-cancer-stem-cells/ | 2023-12-11T05:51:36 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679103558.93/warc/CC-MAIN-20231211045204-20231211075204-00032.warc.gz | 0.897836 | 19,790 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__191123303 | en | This article first appeared in the : Am J Cancer Res. 2017; 7(7): 1588–1605.
Published online 2017 Jul 1.
The use of natural products to target cancer stem cells
This article has been cited by other articles in PMC.
The cancer stem cell hypothesis has been used to explain many cancer complications resulting in poor patient outcomes including induced drug resistance, metastases to distant organs, and tumor recurrence. While the validity of the cancer stem cell model continues to be the cause of much scientific debate, a number of putative cancer stem cell markers have been identified making studies concerning the targeting of cancer stem cells possible. In this review, a number of identifying properties of cancer stem cells have been outlined including properties contributing to the drug resistance and metastatic potential commonly observed in supposed cancer stem cells. Due to cancer stem cells’ numerous survival mechanisms, the diversity of cancer stem cell markers between cancer types and tissues, and the prevalence of cancer stem cell markers among healthy stem and somatic cells, it is likely that currently utilized treatments will continue to fail to eradicate cancer stem cells. The successful treatment of cancer stem cells will rely upon the development of anti-neoplastic drugs capable of influencing many cellular mechanisms simultaneously in order to prevent the survival of this evasive subpopulation. Natural compounds represent a historically rich source of novel, biologically active compounds which are able to interact with a large number of cellular targets while limiting the painful side-effects commonly associated with cancer treatment. A brief review of select natural products that have been demonstrated to diminish the clinically devastating properties of cancer stem cells or to induce cancer stem cell death is also presented.
Keywords: Cancer stem cells, drug resistance, metastasis, natural products, drug discovery, cancer recurrence, polyphenols, alkaloids, flavonoids, chemotherapy
Modern chemotherapy, radiotherapy, and other antineoplastic regimens have made the treatment of many solid tumors possible and have given hope to those diagnosed with cancer. However, the prognosis for many cancer patients remains bleak due to the high rate of cancer recurrence and multiple drug resistance (MDR) seen after initial chemotherapy treatments. Metastatic cancers affecting multiple organ systems are particularly difficult to treat and oftentimes demand the partial or complete surgical resection of multiple tissues. Cancer stem cells (CSCs) potentially explain many of the shortcomings of established chemotherapy treatments.
CSCs are distinguished as a small population of tumor cells which are able to form phenotypically diverse tumors, as wells as self-renew and differentiate. They are described as belonging to a group of tumor initiating cells (TICs) which may or may not possess stem-like characteristics, but debate remains as to how large a proportion of TICs are indeed stem-like. Additionally, it is not clear whether or not the plasticity of tumor cells allows any cell to become stem-like and gain the capability to recapitulate heterogeneous tumors. The role of CSCs in tumor formation was first identified by Bonnet and Dick in the late 90s . In this paper, the CD34+/CD38– subpopulation of cells from acute myeloid leukemia were shown to form tumors in immunodeficient NOD/SCID mice with higher efficiency than the CD34+/CD38+ subpopulation. The ability of CSCs to asymmetrically divide, allowing the CSC to self-renew as well as differentiate to produce a heterogeneous tumor containing multiple cell phenotypes, was also identified. Since this discovery, the CSC hypothesis has been tested rigorously, and evidence that CSCs play a crucial role in tumor development for many different cancers has been reported. These include breast carcinoma [2,3], colorectal carcinoma , head and neck squamous cell carcinoma , hepatocellular carcinoma [6,7], lung carcinoma , ovarian adenocarcinoma , glioblastoma , and pancreatic carcinoma among others.
According to the CSC model, cancer recurrence after treatment is due to the superior resistance of CSCs to cellular toxins and insults. While current treatments are capable of eradicating the bulk of the tumor mass, the lingering CSCs are able to form new, fully developed tumors from a small number of cells or even a single cell. CSCs are thought to resist treatment through several cellular mechanisms including the overexpression of drug efflux pumps, quiescence, and detoxifying enzymes . A high population of CSCs within a tumor has subsequently been linked to MDR and a poorer prognosis for cancer patients . Furthermore, the cellular machinery of CSCs has been shown to allow for epithelial-mesenchymal transition (EMT), a process by which epithelial cells lose their cell-to-cell and/or cell-to-matrix adhesion and can survive in a migratory state . By undergoing EMT, migrating to other organs, and reattaching by mesenchymal-epithelial transition (MET), CSCs are hypothesized to initiate the formation of metastatic tumors.
Current methods for the treatment of cancer have been demonstrated to be insufficient in eliminating CSC populations from a number of cancer types. CD133+ glioma CSCs have been shown to resist radiation therapy to a higher degree than their CD133– counterparts . Breast CSCs exhibit a similar resistance to radiotherapy in addition to common chemotherapy treatments [16,17]. Furthermore, the CSC population in residual breast cancer tumors has been shown to increase significantly following chemotherapy treatments, nearly doubling the tumorigenic potential of the residual cancer cells in immunodeficient SCID mice . Treatments targeting a specific molecule or surface marker are likely to fail to eliminate CSCs due to the multiple survival pathways activated in CSCs in addition to the ambiguity of CSC markers across different tissue types, the presence of commonly used CSC markers in healthy tissues, and the often required combination of markers used to denote CSC populations. Treatments capable of reducing CSC populations will therefore require the development of novel, diverse, and multi-targeted approaches for cancer treatment. Due to the numerous, still poorly understood characteristics of CSCs, the discovery of CSC targeting therapies will likely be the result of opportunistic screening of new or known compounds against CSC populations.
Natural products may be the key to discovering novel treatments demanded by the difficulty of treating CSCs. Natural products (NPs) have been a historically rich source of biologically active compounds for the pharmaceutical industry. The value of NPs in medicine is a result of their ability to influence multiple signaling pathways simultaneously while producing diminished, benign side effects. The success of these compounds, especially as they relate to cancer treatment, has led researchers to investigate the effect of a number of NPs on CSCs. Figure 1 summarizes the role of CSCs in cancer formation, metastasis, and relapse in addition to the potential role of natural products in their treatment. In this review, properties distinguishing CSCs as well as properties which give rise to the drug resistance associated with CSCs are identified. A brief review of select NPs which have been shown to target CSCs is also provided.
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Illustration of the Cancer Stem Cell Model’s explanation for tumor formation, metastasis, and recurrence and the potential of natural products in their treatment. Cancer Stem Cells (CSCs) are either formed upon carcinogenesis of somatic cells or stem cells, or they are activated after a period of dormancy (1). These CSCs then asymmetrically divide resulting in a phenotypically diverse tumor consisting of both CSCs and non-stem-like cells (2). Left untreated, the tumor will continue to grow and invade the surrounding tissue, and CSCs undergoing EMT may break off from the original tumor and travel to distant organs (3). The CSCs which reattach throughout the body can then initiate a new tumor, resulting in metastases (4). Using current treatment methods capable of inducing cell death in the bulk of tumor cells, the CSCs are not destroyed due to their enhanced survival traits, such as quiescence and the expression of ALDH enzymes and ABC transporters (5). The remaining CSCs may then go on to recreate the original tumor, sometimes increasing the percentage of CSCs within the tumor and forming multiple drug resistant tumors (6). In other cases, the remaining CSCs will enter a state of dormancy within the body and remain undetected for long periods of time before reactivating and initiating the formation of a new tumor, thus resulting in cancer relapse in patients thought to be cancer free (7). As a result of these issues, new treatments are being investigated which can target CSCs. Natural products have shown the potential to induce cell death in CSCs, cause CSCs to differentiate, or sensitize CSCs to conventional chemotherapy treatments (8). Once the CSCs have been eliminated, the remaining tumor may diminish in size and can be subsequently eradicated through the use of conventional antineoplastic therapies (9).
Identifying cancer stem cells
One of the major challenges facing cancer stem cell research is accurately defining which tumor cell subpopulations are stem like. The gold standard for identifying CSCs remains the ability of a small number of cells to generate a fully developed tumor when injected into immunocompromised mice, but the cost, time, and labor associated with animal studies have led to the search for markers of stem like cancer cells. Many putative CSC markers have been proposed and subsequently identified as targets for chemotherapeutics. However, the expression of these markers has been shown to be inconsistent across CSCs from different tissues and tumor phenotypes [18,19]. Additionally, many of the reported CSC markers are possessed by healthy stem cells and even non-cancerous, non-stem-like cells, posing a challenge to the development of targeted therapies based upon these markers.
Oftentimes, a combination of supposed CSC markers is required to denote the CSC population. For example, a common population of cells within breast cancer that has been deemed breast cancer stem cells are CD44+/CD24–/ESA+ . The most notable among these putative markers are the surface proteins CD44 and CD133 which have been used to identify CSCs in a wide array of cancer types. In addition to these supposed markers, certain properties of CSCs have also been use to distinguish them from the rest of the tumor population. For example, cells known as the side population (SP) have been shown to possess a high percentage of TICs [7,9,10]. Tumors cells within the SP are distinguished by their ability to exclude Hoechst 33342 fluorescent stain which is typically assessed via flow cytometry.
Investigators have attempted to isolate populations of CSCs using these properties combined with flow cytometric techniques or selective growth environments. Using these purified populations of CSCs, their tumorigenic properties and specific responses to drug candidates can be better investigated. Low purity of isolated populations, the ability of CSCs to differentiate into phenotypically diverse populations, and disagreement over which markers should be used to identify CSCs still pose major hurdles to many of these techniques. A brief review of common CSC markers and characteristics used to identify or isolate CSC populations is provided below.
Cluster of differentiation 44 (CD44) is a very commonly utilized marker for CSCs. CD44 proteins are integral membrane glycoproteins which play a role in cell attachment to the extracellular matrix by binding to hyaluronan (HA). CD44 is often used in combination with other markers to denote CSCs; however, in cases such as head and neck squamous cell carcinoma, CD44 has also been used alone to identify cancer cells capable of self-renewal and differentiation . The expression of this marker has been used as a putative marker for cancer stem cells in such tissues as breast , ovarian , pancreatic , and bladder along with many others. CD44 regulates the growth, migration, and invasion characteristic of CSCs in addition to modifying the extracellular matrix of tissues to support new tumor formation [23,24]. Interestingly, cells expressing CD44 also produce a higher amount of the cytokine transforming growth factor beta (TGF-ß) which has been shown to aid EMT . Further, HA-CD44 binding activates protein kinase Ce, which in turn phosphorylates the stem cell maintenance transcription factor, Nanog. Nanog then begins a signaling cascade which results in the upregulation of ATP binding cassette B1 (ABCB1), a drug efflux pump, contributing to MDR . Reducing the population of CD44 expressing cells in tumor populations, therefore, has the potential to diminish the CSC population and limit invasion, metastases, and drug resistance in a broad spectrum of cancers.
Cluster of differentiation 133 (CD133) is a pentaspan surface membrane protein that is also commonly used as an indicator of CSCs. Interest in this marker as an indicator of CSC was generated by its original use as a hematopoietic stem cell marker . CD133 has been identified as a CSC marker in glioblastomas as well as colorectal , ovarian [27,28], hepatocellular , lung , and pancreatic cancers. CD133 is localized to membrane protrusions and microvilli, but little is known about the function of this protein in cells or CSCs in particular. It is apparent that while CD133 can be used to distinguish CSC populations, it may not play a direct or critical role in cancer formation or CSC maintenance. A study demonstrating this point showed that a CD133+ colon cancer population was able to differentiate and self-renew even when CD133 expression had been knocked down . What is clearer is that CD133 has been positively correlated with poor outcomes for cancer patients. A meta-analysis of 603 gastric cancer patients from 8 different studies revealed that CD133 overexpression was linked to lymph node metastasis, distant metastasis, higher drug resistance, an increased relapse rate, and a lower 5-year survival rate . The widespread presence of CD133 in putative CSC populations across numerous tissues, coupled with the poor prognosis of patients overexpressing CD133, validates this marker as a dependable marker for CSCs as well as a potential cancer drug target.
Cluster of differentiation (CD24) is yet another surface marker used to demarcate CSC populations. CD24 is a notable CSC marker as both its presence and absence [3,32] has been used to denote CSC phenotypes depending upon the tissue. CD24 is a surface expressing glycoprotein, also known as heat stable antigen (HSA), which was initially identified as a marker for hematopoietic subpopulations, typically B-cells. Numerous functions have been suggested for this protein, including signaling and cell attachment, and its expression can be seen in various cell types, most commonly acting as a marker of differentiation for hematopoietic and neuronal stem cells. CD24 is often seen in the context of adaptive immune response in which its expression can be seen in pre or immature-B cell populations or in activated T-cells . The function of CD24 in tumor cells may be explained by the association of the marker with P-selectin, a molecule expressed by platelets and vascular endothelium, which may play an important mechanistic role in cancer cell adhesion and metastasis. In addition to acting as positive or negative marker for CSCs, depending upon the tissue of origin, the expression of CD24 has also been associated with poor prognosis, larger tumors, and lymph node metastasis in a range of cancers, demonstrating its influence on clinical outcomes [34–36].
ESA or epCAM
Epithelial specific antigen (ESA), also known as epithelial cell adhesion molecule (epCAM) has been used to identify CSCs from breast , colorectal , and pancreatic cancer. As the name implies, ESA is a surface marker typically expressed on epithelial cells, which regulates cell-to-cell adhesion. ESA is overexpressed in a majority of epithelial cancers, such as colorectal cancer, and as a result it has been the subject of numerous studies and targeted chemotherapy strategies. ESA has further been linked to the migratory and invasive capabilities of breast cancer and is highly expressed in breast cancer metastases . By disrupting the expression of ESA, the migration and invasion of cancer cells in vivo can be diminished. The upregulation of this transmembrane glycoprotein, as a result, may play a role in the metastatic potential of proposed CSCs.
Increased aldehyde dehydrogenase (ALDH) activity has been used to identify CSCs with little technical difficulty. ALDH can refer to any number of enzymes classified as aldehyde dehydrogenases which act to catalyze the oxidation of aldehydes entering or produced within the body. By oxidizing aldehydes, these enzymes transform potentially deleterious compounds into carboxylic acids, preparing them for cellular metabolism. In this way they act to detoxify the cell. ALDH enzymes are highly expressed in liver cells, but their expression has also been used to distinguish numerous progenitor cells including hematopoietic stem cells and neural stem cells among others. ALDH enzymes are therefore theorized to contribute to stem cells’ robust ability to survive chemical stresses throughout the body. The cytoprotective effect of ALDH enzymes utilized by these stem cell populations, however, can also be used to protect CSCs from chemotherapy treatments.
ALDH activity has been used to identify CSCs of various tissues including colon , breast , head and neck squamous cell carcinoma , ovarian , and lung . ALDH1 is commonly proposed to be the source of ALDH activity in CSCs, and its expression has been widely used as a CSC marker. However, unspecific ALDH activity can also be utilized to categorize cells as CSCs using the ALDEFLUOR assay. The ALDEFLUOR assay contains BODIPY-aminoacetaldehyde (BAAA) which enters intact, viable cells and is oxidized by ALDH enzymes producing fluorescent BODIPY-aminoacetate (BAA). This fluorescence can be detected using fluorescent microscopy or flow cytometry. The non-cytotoxic nature of ALDEFLUOR additionally enables sorting of live CSC populations via fluorescence-activated cell sorting (FACS). Identification of CSCs using ALDH activity assays is a powerful tool for cancer researchers due to this ability to separate viable subpopulations combined with the association of ALDH activity with MDR.
Hoechst 33342 exclusion
Hoechst 33342 is a stain capable of permeating intact cell membranes, which produces blue fluorescence when bound to nuclear DNA. This property is used to visualize nuclei, similar to 4’,6-diamidino-2-phenylindole, dihydrochloride (DAPI), while maintaining cell viability. Stem cells and other cells overexpressing drug efflux pumps possess the unique ability to exclude this stain, and as a result Hoechst 33342 exclusion has been used to label various progenitor cells such as hematopoietic stem cells . The drug efflux pumps responsible for Hoechst 33342 dye exclusion may further contribute to MDR in cancer cells. Hoechst 33342 excluding cells, also known as the side population (SP), of tumors have therefore been investigated as a source of drug resistant CSCs. SP cells have been shown to exhibit stem-like properties in hepatocellular , lung , ovarian , breast and other cancers as well as exhibiting enhanced drug resistance. Like the ALDEFLUOR assay, segregation of hypothesized CSCs using Hoechst 33342 exclusion can be combined with FACS techniques to isolate a viable CSC populations based upon a characteristic associated with MDR.
Epithelial-mesenchymal transition (EMT) is the process undergone by epithelial cells in which the cells alter their morphology, lose their polarity, and break cell-cell or cell-matrix adhesions. In this way, the cells gain mobility and invasive potential. EMT is an essential process during development and wound healing, allowing epithelial cells to produce a population of mobile cells able to migrate to target locations and reestablish basal and apical polarity once there . CSCs are hypothesized to possess enhanced EMT capability, enabling the cells to survive in the absence of cellular adhesion in addition to enhancing their resistance to apoptosis. CSCs having undergone EMT are thought to then reattach and produce metastatic tumors or circulate throughout the body in a dormant state, only to become active years later and cause distant cancer relapse to occur. The ability of CSCs to undergo EMT can be investigated by determining the expression of EMT related proteins such as Twist, Snail, or N-cadherin .
More commonly, however, EMT capability is assessed by removing any opportunity for cellular attachment. This can be accomplished through the use of non-adherent well plates, stirred bioreactors, serum-free growth conditions, or encapsulation in hydrogels. When in these conditions, cells without EMT capability will die leaving only cells that have undergone the transition. The remaining cells often grow in what are referred to as tumorspheres which have been shown to be enriched in CSCs in numerous tissues [49–51]. A major drawback of using these selective growth environments is the relatively low purity of CSCs in the resulting population. Further, CSCs within tumorspheres of a large enough size are likely to differentiate into phenotypically diverse cells. Still, drug discovery efforts directed at limiting the EMT capability of CSCs should be encouraged as this ability lies at the heart of the spread and recurrence of cancer that plagues many patients.
Drug resistance in cancer stem cells
While resistance to chemotherapy treatments is not necessary to define CSCs, drug resistance is commonly associated with CSC populations. In fact, when resistance to a drug is induced, an increase in the percentage of cells possessing CSC markers has been observed . Resistance to specific chemotherapy agents in cancer cell lines is typically promoted in vitro by exposing the cells to gradually increasing doses of the drug or by exposing the cells to several cycles of clinically relevant chemotherapy doses followed by drug free media to mimic the treatment patients actually receive. The enrichment of CSCs following chemotherapy regimens observed both in vitro and in clinical studies has enormous implications on drug discovery efforts and future cancer treatment. Without the ability to target and kill CSCs, chemotherapy treatments will continue to leave patients at risk for tumor recurrence and developed drug resistance. The following proteins and properties of CSC are thought to contribute to drug resistance in CSCs and therefore represent ideal targets for future chemotherapy or chemotherapy sensitizing drug discovery efforts. It is important to note, however, that healthy stem cells share many of the properties imparting drug resistance to CSCs, and as a result targeting these properties may lead to unwanted side-effects on otherwise healthy tissues.
ATP-binding cassette (ABC) transporters are transmembrane proteins that serve a crucial cytoprotective role for healthy stem cells throughout the body. The function of these proteins is to pump toxic compounds from the cell body before their deleterious effects can occur. These pumps are able to act on a large variety of compounds including many chemotherapeutic agents. The expression of ABC transporters has been used to indicate CSC phenotypes in multiple tissues and also plays a role in developing the multiple drug resistance (MDR) typical of CSCs . Members of the ABC transporter family that appear to be highly expressed in CSCs include, but are not limited to, ABCB1, ABCG2, and ABCB5 . The expressions of these proteins have been suggested as markers for CSCs, but the lack of appropriate antibodies makes their detection more difficult than previously discussed markers. The ability of the SP to exclude Hoescht 33342 is a result of ABC transporters, specifically ABCG2, making SP isolation an indirect method of CSC isolation based upon ABC transporter expression .
Many of the ABC transporter proteins have been “discovered” multiple times in the context of chemotherapy resistance leading to confusion in their identification. For example, ABCG2 is often referred to as breast cancer resistance protein (BCRP) alluding to its ability to confer MDR to breast tumor cells. ABCG2 expression has been identified in the drug resistant subpopulations of many cancer models including K562 chronic myeloid leukemia cells and MCF7 breast adenocarcinoma to name a few . The cell lines in these experiments were made resistant through selection with various chemotherapies such as doxorubicin.
ABCB1 is another ABC transporter with multiple aliases. ABCB1 has been referred to by the names multidrug resistance protein 1 (MDR1), cluster of differentiation 243 (CD243), and most commonly P-glycoprotein 1 (P-gp). ABCB1 contributes to the efflux of many widely used chemotherapeutic agents including anthracyclines, vinca alkaloids, and taxanes making it a highly clinically relevant MDR protein . Reduction of the expression of ABCB1 has been shown to lead to an increased chemotherapy sensitivity of colorectal CSCs in addition to MDR cell lines of differing origin . By targeting ABC transporters, the unique resistance of CSCs can theoretically be reversed, sensitizing them to traditional chemotherapy treatments.
Another strategy CSCs employ in order to exhibit MDR is the rapid metabolization of the chemotherapy agents they are subjected to. As mentioned previously, the presence of ALDH enzymes and their activity is a commonly used marker to identify CSCs. ALDH enzymes exert their effect by oxidizing aldehyde groups of drug molecules, preparing them for future cell metabolism and thus detoxifying the cell. ALDH enzymes may also play a role in the differentiation of healthy and malignant stem cells. Inhibition of ALDH activity in ALDHhi/CD44+ putative breast CSCs convincingly resulted in a loss of MDR . Interestingly, the inhibition of ALDH activity using diethylaminobenzaldehyde (DEAB) further sensitized these CSCs to radiation therapy. By eliminating ALDH activity from tumors, the breakdown of chemotherapeutic agents within the tumor will be slowed resulting in a more effective treatment. Cytotoxic compounds which do not act as substrates for ALDH enzymes or that reduce their activity may have a unique ability to induce apoptosis in CSCs and act as more effective long-term treatments.
Pro-survival signaling and stem cell maintenance
CSCs hijack many of the pro-survival signaling cascades and maintenance proteins seen in healthy stem cells. In this way, CSCs have a tendency to survive cellular stresses capable of eliminating differentiated cancer cells in a similar fashion to non-malignant stem cells. For example, mechanistic target of rapamycin (mTOR) and signal transducer and activator of transcription 3 (STAT3) play a role in the maintenance and proliferation of healthy and cancer stem cells. The activation of phosphatase and tensin homolog (PTEN) and subsequent inhibition of mTOR and STAT3 results in a significant decrease in CSC viability and overall tumor drug resistance .
The stem cell maintenance proteins Wnt, Hedgehog, and Notch are also upregulated in CSCs. These molecules play a major role in maintaining the stem-ness of CSCs and activating the expression of stem cell related transcription factors such as octamer-binding transcription factor (Oct4) and Nanog as well as influencing EMT . Stem cell maintenance proteins such as these ensure CSCs will continue to asymmetrically divide, allowing the CSC phenotype to persist in a number of harsh conditions. Dysregulation of these pathways is hypothesized to promote gradual CSC differentiation leading to decreased tumor viability in response to chemotherapeutics, making them an attractive target for the treatment of both bulk tumors and CSCs.
Cellular quiescence is defined by a reduced occurrence of mitotic divisions within a cell population. Quiescence is recognized as a trait of most somatic stem cells, allowing them to survive in a state of relative dormancy and reduce the accumulation of DNA mutations over time . While debate remains as to whether or not chemotherapy agents have a diminished effect on quiescent cells, experiments on leukemia stem cells have shown that forcing these cells out of their dormant state results in increased drug sensitivity . The hypothesis behind this pathway for MDR is that diminished cellular metabolism, failure to proceed throughout the entirety of the cell cycle, and lack of DNA multiplication allows CSCs to avoid activating the targets of many chemotherapeutic toxins. Quiescence of CSCs not only potentially influences MDR, but also enables CSCs to remain dormant at the site of the original lesion or migrate throughout the body for years before attaching and initiating new tumors. Targeting the quiescence of CSCs has the potential to increase the efficacy of current therapeutic methods against CSCs within the original tumor as well as prevent CSCs from entering dormant states capable of initiating new tumors in patients in remission.
Natural products targeting cancer stem cells
Natural products (NPs) have played an important role in medicine for much of recorded human history. The earliest recorded use of medicinal plants dates back approximately 5000 years to a list of Sumerian drug recipes written on a clay tablet, but there is evidence that Neanderthals may have used plants for medicinal purposes as far back as 60,000 years ago [63,64]. Even today many people in the world rely on medicinal plants for their healthcare needs. It is estimated that 70-95% of people in most developing countries use traditional medicine for their primary healthcare needs . Traditional Chinese and Ayurvedic medicine have historically served as primary healthcare for many people in developing nations, and both systems have drawn the attention of pharmocognosists from around the world.
Active compounds from various organisms have had great success as pharmaceuticals. This is especially true in the case of cancer chemotherapeutics. Between 1981 and 2006, 63% of anticancer drugs being used came from NPs, were inspired by NPs, or were synthesized from a natural pharmacophore . The most profitable chemotherapy drug in history, taxol (or paclitaxel), is a natural product derived from the bark of the Pacific Yew Tree . Taxol was discovered through a random screening of approximately 15,000 species of plants , but targeted screening of known medicinal plants for anticancer properties has also been historically successful. For example, the vinca alkaloids vincristine and vinblastine have been used clinically in cancer therapies for over 50 years . These compounds were isolated from the rosy periwinkle, Catharanthus roseus, a plant used in both traditional Chinese medicine and Ayurvedic medicine. Bacteria have also been a source of successful anticancer agents. Anthracyclines, such as doxorubicin, are isolated from certain Steptomyces bacteria and have been used to treat breast cancer for decades .
With advances in technologies such as high throughput screening (HTS) and combinatorial chemistry in the 90’s, the cancer related drug discovery efforts of many pharmaceutical companies shifted to targeted therapies . These targeted, receptor specific therapies relied upon small synthetic molecules or antibodies that could act as “magic bullets” to treat specific cancer cells. Combinatorial chemistry has allowed vast libraries of new chemical entities to be generated synthetically which can be tested against disease related targets. Thousands of compounds from combinatorial chemistry libraries can be analyzed every day using HTS . In addition, advances in proteomics and genomics have enabled researchers to attempt to model molecules that can interact with specific biological targets. The initial success of these targeted therapies including Gleevec and Herceptin led many to believe that traditional NP based drug discovery had become obsolete .
However, the limited number of successful drug candidates from targeted therapies, the relatively small number of cancers successfully treated with new therapies, and the higher risk of cancer developing a resistance to treatment created a renewed interest in natural product drug discovery in the late 2000’s . The limited efficacy of targeted therapies is of increased likelihood in CSCs, due to the lack of agreed upon universal CSC markers and the many survival mechanisms which they employ. Numerous NPs and their derivatives have shown early clinical success or have received FDA approval for the treatment of cancer since the recent renewal in their interest [46,72]. Despite the obstacles facing the screening of NPs using HTS, they have shown many advantages over synthetic chemical entities. Natural products are thought to possess “privileged structures” that are specialized to interact with biological targets allowing them to influence multiple cellular pathways simultaneously. This ability is crucial in combatting cancer and CSCs, as the robust survivability of cancer is often the result of many different mechanisms. Additionally, the chemical character and diversity of NPs is more favorable than that of synthetic molecules. When compared to synthetic libraries, NP libraries tend to have more chiral centers, higher steric complexity, fewer heavy atoms, more solvated hydrogen-bond donors and acceptors, and a larger variety of molecular properties . Furthermore, historic use of a medicinal plant from which a NP is isolated can speak to the safety of compound for human consumption and the potential to limit sideeffects.
The continued ability of natural compounds to compete with synthetic chemical entities has shown that NP based drug discovery is still relevant and capable of advancing the treatment of cancer. It is likely that the successful screening of NPs for cancer killing potential can be successfully applied to screening for CSC targeting agents. A few promising NPs have been utilized to target CSCs in vivo and in vitro. Figure 1 depicts the role that such NPs may play in preventing cancer metastasis and recurrence. These compounds may have the potential to sensitize CSCs to conventional treatments, directly induce cell death in CSCs, force CSCs to differentiate, or prevent CSCs from entering a dormant and more resistant state. A brief review of these compounds can be found below. The reader of this review is directed to other reviews for a more comprehensive list of NPs capable of targeting CSCs [12,73,74].
Many natural products used as pharmaceuticals can be classified as polyphenols. Polyphenols are structurally defined by the presence of aromatic benzene rings bonded to hydroxyl groups, but they encompass a number of structurally diverse compounds. These subgroups include flavonoids, stilbenes, tannins, lignans, and phenolic acids among others. Polyphenols of various groups have been demonstrated to regulate inflammation, angiogenesis, cell growth, invasiveness, and apoptosis in vitro . As a result, they have been studied extensively in the context of cancer prevention and metastasis. Recently, these investigations have been extended to determine the effect of polyphenols on CSCs. The polyphenols resveratrol and curcumin are notable examples of NPs that have been shown to exhibit cytotoxic effects on CSCs.
Resveratrol is a polyphenolic stilbene derivative most commonly found in the skin of grapes and berries. It has undergone extensive examination for its anti-inflammatory and antioxidant properties in addition to many other useful biological properties. These attributes give resveratrol the attractive potential to act as a cancer chemopreventative. Resveratrol has been shown to induce apoptosis and promote S-phase arrest of select cancer cells. This potential was demonstrated in Hep G2 hepatocyte carcinoma cells in vivo at concentrations ranging from 10 to 50 µM . At concentrations higher than 50 µM, however, resveratrol induced G1/G0 arrest which was confirmed in a separate study using a number of ovarian cancer cell lines [76,77]. Resveratrol has further been shown to induce cell death through a non-apoptotic mechanism at concentrations between 50 and 100 µM in a ovarian cancer cell lines . This variety of mechanisms demonstrates the ability of resveratrol, like other NPs, to influence numerous biological mechanisms simultaneously making it an attractive anticancer agent.
Resveratrol may also be able to eliminate CSC populations from tumors. The compound has been shown in a study by Shankar et al to induce caspase-3/7 activated apoptosis in CD44+/CD24+/ESA+ pancreatic CSCs at 10 to 30 µM concentrations. The study also found that 10 to 20 µM resveratrol was able to inhibit both stem cell maintaining factors, such as Nanog and Oct-4, as well as anti-apoptosis proteins of the Bcl-2 family in the pancreatic CSCs. Additionally, EMT proteins, such as Snail and Slug, as well as the EMT capability of the pancreatic CSCs in non-adherent conditions was inhibited in response to 10 to 20 µM of resveratrol. Further, the expression of the drug efflux pump ABCG2 was inhibited after administration of 10 to 30 µM of resveratrol, potentially sensitizing the cells to conventional chemotherapy treatments. The apparent ability of resveratrol to target CSCs and act as a chemopreventative and anti-inflammatory drug was further demonstrated using a mouse tumor model. The frequency of tumor formation in KrasG12D mice, spontaneous pancreatic tumor forming mutants, was significantly diminished when treated with resveratrol for 10 months . The ability of resveratrol to induce apoptosis in CSCs as well as reduce their tumorigenic potential in vivo was additionally supported in a CD24–/CD44+/ESA+ model of breast cancer stem cells. In this study, apoptosis was induced in the breast CSCs through a FAS mediated pathway after incubation with 50 or 100 µM resveratrol. The tumorigenic potential of the cancer stem cells was significantly diminished in female nude mice through the administration of either an oral gavage or intraperitoneal injection of 22.4 kg/body weight of resveratrol, giving significant evidence that resveratrol is able to disrupt tumor formation by targeting CSCs .
While resveratrol exhibits extremely promising anticancer effects in preclinical studies in vivo and in vitro, resveratrol has failed to translate this success to clinical trials. This is due, in large part, to extremely low bioavailability, high effective dosages, and the rapid metabolism of resveratrol to glucuronide, sulfate, and hydroxylate conjugates [80,81]. These conjugates, once absorbed into the bloodstream fail to provide the same health benefits as free resveratrol. As a result, there have been efforts to engineer resveratrol formulations or drug delivery systems aimed at increasing the bioavailability of resveratrol. These include formulations to stabilize resveratrol in the body, formulations to increase the aqueous solubility of resveratrol, and encapsulation of resveratrol in various lipids, micelles, or polymer structures with the aim of sustained, concentrated, and/or targeted release [80,81].
Curcumin is another polyphenol which has been thoroughly investigated for its anticancer properties. This compound is a major component of turmeric, a spice widely used in Indian and many Middle-Eastern cuisines. Curcumin has been shown to exhibit an anti-inflammatory effect and promote apoptosis in cancer cells . It has been used in clinical trials demonstrating its safety at high doses and activity against pancreatic neoplasms in human patients despite its low bioavailability . The antitumor properties demonstrated by curcumin have led to investigations of its potential to target CSCs.
Curcumin has been used to inhibit the formation of breast cancer mammospheres in vitro by 50% and 100% using 5 µM and 10 µM concentrations, respectively, demonstrating the ability of curcumin to inhibit CSC’s ability to undergo EMT . An analogue of curcumin, GO-Y030, was demonstrated to induce apoptosis, diminish tumorsphere formation, and inhibit STAT3 phosphorylation in ALDH+/CD133+ colon CSCs when used at 2 to 5 µM concentrations. The ability of this analogue to target tumor initiating cells was further demonstrated using a NOD/SCID mouse model. When given a 50 mg/kg intraperitoneal injection of GO-Y030, the average tumor weight resulting from a xenograft implantation of 1 × 105 CSCs was diminished by 58.10% . Curcumin has also been suggested as a supplement to current chemotherapy treatments. Curcumin in combination with FOLFOX, a commonly prescribed combination of leucovorin calcium, fluorouracil, and oxaliplatin, was able to decrease the viability and diminish EMT of colon CSCs to a higher extent than FOLFOX alone .
While curcumin shows great potential as an anticancer agent and has been used in a number of clinical trials against cancer, it suffers similar shortcoming to resveratrol. Namely, the rapid metabolism and excretion of curcumin, along with its hydrophobicity, results in low bioavailability which has been demonstrated using mouse models [87,88]. Numerous drug delivery studies have been conducted to increase the bioavailability of curcumin including the use of adjuvants to interfere with metabolism, encapsulation in liposomes and nanoparticles, and the use of more stable structural analogues .
Flavonoids are a major class of polyphenolic secondary metabolites found in numerous medicinal plants. They are derived from flavone which contains two phenyl rings and one heterocyclic ring. Flavonoids are commonly found compounds throughout the plant kingdom, and as a result, they are widespread throughout the human diet. Due to their abundance in fruits, vegetables, nuts, spices, and herbs, a flavonoid rich diet has been suggested as a feasible means of cancer chemoprevention . Certain flavonoids including, quercetin and kaempferol, have been implicated as apoptosis inducers, antioxidants, inflammation regulators, and angiogenesis inhibitors. Further, certain flavonoids have been shown to have an effect on heat shock proteins, multiple drug resistance, adhesion, metastasis, and angiogenesis . The high number of CSC related properties which seem to be affected by flavonoids have led to their investigation as CSC targeting agents. A review of one such flavonoid, quercetin, is presented below.
Quercetin is a flavonol secondary metabolite found throughout many species of plants. Quercetin is a known anti-inflammatory agent and anti-oxidant which has been demonstrated to induce programmed cell death in many malignant cancer cell lines. Quercetin has been shown to interfere with a number of cellular pathways associated with the formation and maintenance of human cancers including down regulating P53, inhibiting tyrosine kinase, inhibiting heat shock proteins, and inducing type II estrogen receptor expression . Quercetin has further drawn attention as a potential CSC targeting therapeutic.
Not only has quercetin been shown to inhibit the proliferation of CD133+ colon CSCs at a concentration of 75 µM, but it also increases the sensitivity of these cells to doxorubicin (Adriamycin). In fact, when combined with 50 µM quercetin, doxorubicin doses were more effective at inhibiting CSC proliferation in vitro than doxorubicin doses three times more concentrated but lacking quercetin . This finding demonstrates the potential of quercetin and other natural products to enhance the use of other chemotherapeutics to eliminate CSC populations. The use of lower doses of chemotherapeutic agents in combination with natural products such as quercetin may result in diminished off target toxicity while also inducing apoptosis in CSCs, improving patient outcomes, lowering the risk of cancer recurrence, and preventing metastasis formation.
Other CSC models have been targeted using quercetin including CD44+/CD133+ prostate CSCs. At a concentration of 20 µM, quercetin lowers the viability of prostate tumor spheroids grown in non-adherent flasks as well as diminish the migratory, invasive, and colony forming potential of CD44+/CD133+ prostate CSCs . In this same publication, quercetin was shown to synergize with epigallocatechin gallate, a catechin found in tea, synergistically amplifying the above effects on these prostate CSCs. As is the case with many other NP’s, however, quercetin’s poor solubility, poor permeability, and instability result in diminished bioavailability . The relatively high dose of quercetin required to elicit a biological response in combination with these issues warrant further drug delivery efforts to increase the lifetime and concentration of the compound at the site of the neoplasm.
Alkaloids are a class of pharmacologically active organic compounds distinguished by the presence of nitrogen and aromatic rings in the chemical structure. Alkaloids are produced throughout the plant kingdom, but are usually found in higher plants . Many alkaloids have been used throughout history in the medical field from quinine for the treatment of malaria to vinblastine for the treatment of multiple carcinomas. Several alkaloids have been used clinically in the treatment of cancer with great success, demonstrating their importance in the field. A small group of alkaloid compounds have even been shown to differentiate between healthy and cancerous DNA, inhibiting in vitro cancer DNA synthesis while leaving healthy DNA unaffected and resulting in a potential cancer treatment with diminished side-effects . New investigations on alkaloids are still being conducted showing further antineoplastic, anti-metastatic, and MDR inhibiting potential . These results suggest a potential for alkaloids to eliminate CSCs, and indeed, a number of compounds belonging to the alkaloid family have been shown to target CSCs in vitro and in vivo. Three promising anti-CSC alkaloids, dihydrocapsaicin, piperine, and berberine, are presented in the following sections.
Capsaicin is the secondary metabolite and alkaloid responsible for the hotness of many species of pepper. Dihydrocapsaicin (DHC), a saturated derivative of this compound, has exhibited numerous anti-neoplastic properties. DHC has been shown to induce dose-dependent and catalase regulated autophagic cell death in colon and breast cancer cells when used at concentrations between 50 and 400 µM . However, when autophagic cell death was inhibited through treatment with the inhibitor 3-methyladenine, DHC instead induced caspase-3 activated apoptosis in these cell lines. Further, when apoptosis was inhibited by the addition of peptide zVAD, autophagic cell death was enhanced. This ability to promote separate modes of cell death is a useful tool in targeting CSCs due to the many cell death evading pathways active in CSCs. This ability further highlights the potential of NPs to influence multiple cellular mechanisms and produce a robust cytotoxic effect on cancer cells.
A review of CSC related patents revealed that DHC is further hypothesized to exhibit a cytotoxic effect on neural CSCs . In one of the patents collected in the review, US20090076019A1, a neurosphere assay was invented to screen potential drugs for activity against neural stem cells. As the percentage of putative CSCs are increased in cancer neurospheres, compounds capable of inducing cell death in these spheres can be thought of as agents targeting neural CSCs. DHC was identified in this patent as one of several lead compounds which showed an ability to target CD133+ neural CSCs. The high IC50 values of DHC, however, limit its use as an effective chemotherapeutic agent, especially when one considers the low bioavailability common for many NPs. Further research is warranted to determine if DHC or an analogue can target any phenotype of CSCs with higher efficacy than what has been shown.
Piperine is a promising antineoplastic alkaloid found in black and long pepper. The use of piperine has previously been suggested as a cancer chemopreventative, but it has also demonstrated the ability to induce cell cycle arrest, endoplasmic reticulum stress, and apoptosis when exposed to colon cancer in vivo at concentrations between 75 and 150 µM . The treatment of colon cancer cells with piperine has been shown to reduce the ability of the cells to form non-adherent spheres and colonies, suggesting the inhibiting effect of piperine on CSCs. The apoptotic effect of piperine has additionally been confirmed using prostate cancer cells .
The ability of piperine to target stem cells specifically has been investigated in a breast tissue model. After pre-treatment with 5 to 10 µM piperine, the mammosphere formation potential, ALDH expression, and Wnt signaling of unsorted breast tissue was significantly diminished . Interestingly, the differentiated population of these cells was seemingly unaffected by the piperine treatment. The potential of piperine to target CSCs without affecting other cells is a fantastic example of the robust ability of NPs to influence molecular pathways while imparting only benign side effects. Piperine has additionally been suggested for use in combination therapies with compounds, such as resveratrol or curcumin, due to its ability to inhibit metabolic pathways. By slowing the glucuronidation of these compounds, piperine inhibits the metabolism and clearing of NPs and increases their bioavailability . By inducing a cytotoxic effect on CSCs and increasing the efficacy of other compounds, piperine acts as an ideal complementary medication to other NP chemotherapies.
Berberine is a tetracyclic, isoquinoline alkaloid found in the roots and stems of numerous plants. Berberine producing medicinal plants have been used as anti-inflammatories in Ayurvedic medicine for years, and the compound has been shown to induce dose-dependent apoptosis, initiated by reactive oxygen species generation, in a broad spectrum of cancers [102,103]. The apoptosis induced by berberine goes through an internal caspase-9 dependent pathway which results in a loss of mitochondrial membrane integrity. Like many natural products, the bioavailability of berberine is low in the body, limiting the potential of berberine as a drug. This obstacle is being overcome through the use of targeting liposomes as a drug delivery system . This delivery system encapsulated berberine into liposomes which were engineered to deliver the compound directly to the mitochondria of CD44+/CD24– breast cancer stem cells. Using this system, 1-50 µM of berberine was able to produce dose-dependent apoptosis in breast CSCs. The drug was further able to induce the expression of the pro-apoptotic protein Bax and activate caspase-9 and caspase-3 leading to apoptosis in CSCs isolated from MCF-7 mammospheres.
Additionally, berberine has been used to inhibit the expression of ABC transporters responsible for MDR in CSCs . Diminishing MDR, especially in CSC populations, makes berberine an attractive complementary medicine when currently accepted cytotoxic agents are unable to kill cancerous cells. An in vivo mouse model in which MCF-7 breast CSCs were injected into female nude mice followed by an array of berberine treatments and formulations demonstrated this synergistic capability. A mixture of 10 mg/kg of berberine liposomes and 10 mg/kg of paclitaxel liposomes was able to reduce the average tumor size in these mice by 85.5% compared to the control after just 21 days . In this way, berberine could be used to either target CSCs alone or in combination with traditional chemotherapy agents.
Many other natural compounds which do not fit into the classifications of polyphenols, flavanoids, or alkaloids have shown promise in targeting CSCs. Retinoids are an example of these compounds. Vitamin A, also known as retinol, generates a number of biologically active retinoids, including All-Trans Retinoic Acid (ATRA). ATRA has found clinical success in the treatment of acute promyelocytic leukemia under the trade name Tretinoin. The drug is marked by its successful induction of remission coupled with relatively mild side effects . The mechanism of action utilized by ATRA is through induction of cellular differentiation of leukemic and hematopoietic cells, and this differentiation induction has further been observed in other types of stem cells . The differentiation potential of retinoids presents a unique potential for cancer treatment, namely differentiating CSCs into a cell population more sensitive to classic chemotherapeutic regimens. Additionally, ATRA acts as an inhibitor of ALDH activity, potentially reversing a cause of MDR in CSCs . ATRA has thus been used to limit the tumorsphere formation ability and CSC percentage of breast cancer cells in vivo .
The lactone antibiotic brefeldin A is another NP that cannot be classified as a polyphenol, flavonoid, or alkaloid. It has shown anticancer potential in a number of cancer types including leukemia, colon, and prostate through p53 independent mechanisms [108,109]. Brefeldin A is produced by certain fungal organisms and acts as a protein transport inhibitor, preventing proteins from traveling from the endoplasmic reticulum (ER) to the Golgi apparatus. Subsequently, brefeldin A initiates ER stress, potentially leading to its apoptotic effects. Recently, brefeldin A has been shown to preferentially induce cell death in suspension cultures over adherent cultures of the human breast adenocarcinoma line MDA-MB-231. In the same publication, brefeldin A also down-regulated the expression of CD44, reduced the ability of the cells to form colonies in soft agarose, and reversed the EMT . Preferential killing of putative CSCs and inhibition of colony forming potential was similarly reported in the human colorectal cancer line Colo 205 . This preferential killing has the potential to diminish CSC populations while limiting the side effects typically associated with chemotherapy.
The cancer stem cell hypothesis, while still being investigated, presents explanations to many of the issues facing cancer treatment today. The CSC hypothesis explains the mechanisms underlying cancer recurrence, metastasis, and, to a degree, multiple drug resistance. Cancer treatments directed toward the eradication of CSCs could lead to higher survival rates and brighter prognoses for patients who fear cancer regression could occur at any time. Current cancer treatments are insufficient in regard to the eradication of CSC populations, likely due to the multitude of survival mechanisms utilized by CSCs and the lack of definitive, universal, single molecule targets that separate CSCs from healthy stem or somatic cells. Natural products have historically been an excellent source of bioactive compounds capable of targeting multiple pathways, and current investigations are underway to screen NPs for their effect on the CSC population of numerous cancer types. Many different NPs have exhibited a range of CSC inhibitory properties, and it is likely that more have yet to be discovered. As a result, NPs should continue to be screened as potential chemotherapy agents, complimentary treatments for compounds already in clinical use, and cancer prevention molecules with special attention focused on their ability to target CSCs. Further, due to the limited bioavailability and rapid metabolism of many NPs, these drug discovery efforts must be coupled with continued efforts to engineer robust drug formulations and delivery systems.
Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number AR063338, and National Science Foundation under Award Number 1631439. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health and National Science Foundation.
Disclosure of conflict of interest
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Articles from American Journal of Cancer Research are provided here courtesy of e-Century Publishing Corporation | medical |
https://www.childrenscancerfoundation.com.au/news/funding-continues-for-the-beaded-journey/ | 2023-12-10T08:25:06 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679101282.74/warc/CC-MAIN-20231210060949-20231210090949-00302.warc.gz | 0.957177 | 1,013 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__86197271 | en | Children's Cancer Foundation
The Beaded Journey will continue until 2024 thanks to a Special Named Fund. The family behind it shared their experience with the program.
From a parent’s childhood cancer heartache comes the continuation of a clinical care program in hospitals until 2024. More Beaded Journey packs are on their way to The Royal Children’s Hospital and Monash Children’s Hospital cancer centres thanks to funds raised by the Lillies for Hope Special Named Fund.
The Fish family – Sarah, Liam, Zoe and Roland – experienced the despair of losing daughter and sibling Lilly at the tender age of six to a Wilms Tumour (kidney cancer) in 2014, following a two-and-a-half-year plight to save her. Lilly’s determination, optimism and hope inspired the family to find a way to honour her life, and support other families going through childhood cancer.
“We are incredibly honoured to be funding The Beaded Journey. It is a program that is very close to our heart, as we experienced the joy that it brought to Lilly while she underwent treatment. We know how important this program is, not only for children in hospitals but for lifting the spirits of their families too”, Sarah, Lilly’s Mum said.
The Beaded Journey allows children to chronicle each milestone and significant procedure throughout their cancer treatment with a different coloured and themed bead.
Special occasion beads also mark birthdays (balloons), special events (rainbow), even travel – and the one bead every child and their family looks forward to receiving, the end of treatment (sunshine).
Families can also use the program’s accompanying Beaded Journey A5 journal to track and record when the beads are achieved and capture thoughts, emotions or memories along the way.
Beads can help children on the ward connect; exploring beads together and sharing their unique treatment and life experiences.
“Lilly loved her rainbow, birthday and milestone beads. She was always excited to see what beads she would receive to represent different special occasions and she read her journal with curiosity, asking about the significance of each bead. Looking back, it was those milestone beads that held hope and importance for all of us as a family.
“The Beaded Journey stands as a tangible reminder of everything Lilly went through. It symbolises her bravery and tells a story of all that she endured. Her beads have become a cherished touchpoint to remember each moment we spent together. We are so happy that this program was part of Lilly’s cancer therapy and can continue for patients today and in the future”, Sarah said.
“It is a real pleasure to assist in implementing The Beaded Journey program at Monash Children’s Hospital (MCH). It is a very popular program within the Children’s Cancer Centre to recognise the journey for children and adolescents receiving treatment. A truly beautiful program and we are very grateful to Lillies for Hope and the Children’s Cancer Foundation for providing the funding to allow this program to run within our service.” ~ Annabelle and Karen, MCH
Comfort First clinicians introduce patients to The Beaded Journey while they are in hospital by offering them a cord with beads that spell out their first name or nickname, as well as a bead representing their diagnosis. They continue collecting beads for each procedure or event.
A Beaded Journey is for all children receiving treatment at the Children’s Cancer Centre who choose to participate.
In receiving The Beaded Journey with Lilly, her Dad Liam remembered, “we were offered the program during Day Oncology at the beginning of Lilly’s treatment in 2012. We recall the children sitting together, waiting to collect their beads with such excitement and anticipation.
We felt it would be something positive and relatable for Lilly, bring some joy and help prepare her for upcoming treatments; they gave Lilly comfort and helped relieve her anxiety about upcoming hospital visits. The beads became a beautiful decoration we kept on Lilly’s IV pole during each admission”.
“Each participant of this program forms a personal attachment to their journey beads. For some, it is an acknowledgment of how far they have come in their treatment journey and how much adversity they have overcome. For others, it encourages positive interactions within the hospital environment or reinforces a job well done. The Beaded Journey program in an invaluable tool which allows clinicians to acknowledge a patient’s experience, assess how they are coping, provide feedback and encouragement, clarify misconceptions and provide education for upcoming procedures.” ~ Kari Peters, RCH
You can contribute towards the Foundation’s psychosocial projects by visiting our Campaign page to pledge your support.
Thank you to the Fish family for sharing their story and their continued support of the Foundation.
Photo credits: Sarah, mum of Lilly. | medical |
https://desertlakedental.com/dr-adel-shayegan.html | 2019-04-25T00:26:03 | s3://commoncrawl/crawl-data/CC-MAIN-2019-18/segments/1555578675477.84/warc/CC-MAIN-20190424234327-20190425020327-00099.warc.gz | 0.959415 | 161 | CC-MAIN-2019-18 | webtext-fineweb__CC-MAIN-2019-18__0__111844067 | en | Adel Shayegan, DMD
Dr. Adel Shayegan is an experienced and compassionate dentist who offers comprehensive, high quality gentle dental care in his state-of-the-art practice.
Dr. Shayegan completed his Doctor of Dental Medicine degree at Tufts University in 1997. He is a member of the Academy of General Dentistry, the American Dental Association and the American Academy of Cosmetic Dentistry.
Dr. Shayegan and his staff are proud of the warm patient-friendly environment they have created and of the lifelong relationships they have built with multi-generational families in the area. Dr. Shayegan welcomes patients of all ages and looks forward to meeting you and offering you the professional, caring and pain free oral health care that you deserve. | medical |
https://eyecareadvisors.com/dry-eye-rescue-clinic/ | 2024-04-12T10:17:26 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296815919.75/warc/CC-MAIN-20240412101354-20240412131354-00578.warc.gz | 0.933992 | 319 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__99523143 | en | Dry Eye Rescue Clinic
Dry Eye Rescue Clinic Boca
The Dry Eye Rescue Clinic, established in 2022, marks a pioneering venture in Florida as the state’s first clinic entirely dedicated to the treatment of dry eye disease. This specialty clinic stands out for its exclusive focus on this condition, offering a comprehensive range of the latest treatments including Intense Pulse Light, Lipiflow, TearCare, Low Level Light Therapy, and advanced eyelid cleaning procedures.
Functioning as a central referral hub, the clinic not only supports the Eyecare Advisors Group practices but also welcomes referrals from doctors across the area, assisting a broad spectrum of patients in need of specialized dry eye treatment.
The Dry Eye Rescue Clinic is designed to be the foundational model for an ambitious nationwide expansion. Dr. Aaron Evans O.D. and his DryEye Rescue Co-Founder, Thiago Pinheiro, now aim to establish a network of similar clinics across the United States.
The success and vision of the clinic are attributed to the collaborative efforts of its leadership team. Kirsten Cooperman, the Administrator and Vice President of Medical Operations, alongside Medical Director Dr. Ryan Beck O.D., plays a crucial role in the clinic’s operations and strategic direction.
The original vision of Dr. Aaron Evans was instrumental in creating this unique facility, designed to address the needs of the millions suffering from dry eye disease.
The Dry Eye Rescue Clinic not only stands as a testament to innovative healthcare but also as a beacon of hope for those affected by this challenging condition. | medical |
https://thereforher.com/form-your-team/ | 2023-06-04T23:15:28 | s3://commoncrawl/crawl-data/CC-MAIN-2023-23/segments/1685224650409.64/warc/CC-MAIN-20230604225057-20230605015057-00261.warc.gz | 0.960696 | 426 | CC-MAIN-2023-23 | webtext-fineweb__CC-MAIN-2023-23__0__251861814 | en | You will be working with a team of doctors and specialists through your treatment. You will often start (and may have already met) with a surgeon and hopefully also a nurse navigator. Your nurse navigator should be someone who is there to answer any questions and provide you guidance throughout the whole treatment experience. Utilize this person. Confirm assumptions, ask for their opinion or ask for referrals to other doctors with them.
Your surgeon will explain the entire treatment process with you and often refer you to other doctors. Your surgeon will also make recommendations and should be giving you enough information to make good choices for her treatment. You especially want your surgeon to be someone who specializes or devotes much of his/her practice to breast diseases.
The other members forming your team will be: a radiologist, oncologist, fertility specialists (if you plan on having children), and a plastic surgeon (for reconstruction if having a mastectomy). Departments don’t always communicate together. It is vital to take notes, keep documents and records in a binder, understand next steps, and confirm action steps between departments.
Remember, you don’t have to stay with the first doctor you talk to. No doctor should tell you what to do, but should only make suggestions. They should be sympathetic, knowledgeable and encouraging.
Don’t ever let a doctor talk you into a decision you don’t feel comfortable with and you should always seek a second opinion if you are ever unsure.
This is your wife’s life and you need to be determined to choose your best options. If anything about a care provider doesn’t sit right with your wife, seek another practitioner. Who you chose as your doctors (like every choice in treatment) is your wife’s decision. You should always offer your thoughts to her, but she is in charge. You are supporting her and her decision.
Line up second opinions right away so you don’t have to wait weeks between doctors. Set up your appointments early and be okay to change or cancel depending on circumstances. | medical |
http://www.dentalitsolutions.com/ | 2020-08-03T14:57:34 | s3://commoncrawl/crawl-data/CC-MAIN-2020-34/segments/1596439735812.88/warc/CC-MAIN-20200803140840-20200803170840-00463.warc.gz | 0.921259 | 245 | CC-MAIN-2020-34 | webtext-fineweb__CC-MAIN-2020-34__0__122398298 | en | Dental IT Solutions has been providing dependable IT solutions for dental practices in Massachusetts and beyond since 2001. As an IT provider that specializes in dental technology, we know how much your patients mean to you. That’s why we’ll handle every aspect of your practice’s IT and eliminate technical distractions so you can deliver outstanding patient care.
We proactively manage and maintain your practice’s technology to ensure smooth operations 24/7.
Bulletproof your sensitive patient records and stay HIPAA-compliant with our state-of-the-art data backup tools.
Send and receive important information securely with our advanced email protection software.
Partnering with Dental I.T. has allowed us to focus on dentistry and running our practices without having to figure out and learn the very confusing and complicated and expensive I.T. world. I am grateful to have them as part of our team.
Billerica Dental Associates
We love Dental IT Solutions! Since signing on with them about 2 years ago we find that we are working with a very professionally run company that delivers the best help we have ever had.
Merrimack Valley Endodontic | medical |
https://www.healtheast.org/pain/faqs.html | 2018-08-19T21:36:37 | s3://commoncrawl/crawl-data/CC-MAIN-2018-34/segments/1534221215393.63/warc/CC-MAIN-20180819204348-20180819224348-00380.warc.gz | 0.938065 | 1,006 | CC-MAIN-2018-34 | webtext-fineweb__CC-MAIN-2018-34__0__173540364 | en | At the HealthEast Pain Center, we are committed to helping you manage your pain and experience an improved quality of life. For your reference, we have compiled the following list of frequently asked questions. If you have further questions, please ask us. We are happy to help.
- What should I do if my medicine is not working?
- What if I have side effects from my medication?
- What happens if my pain narcotic medication is changed?
- What information should I leave on the prescription refill line?
- What should I do if I have a problem after clinic hours or on the weekend?
- How do I get my test results?
- What should I do if my problems or symptoms continue, worsen or come back?
- What if I have more pain after my injection?
- What should I do if I need more information about my condition or treatment?
- What if the prescribed medication, test or treatment is not covered by my insurance?
- What if I need my medical records sent to myself or another party?
- What should I do if I have forms that need to be filled out by my provider?
It may take some time to see the benefits of new medications; however, if you have been on your new medicine for 14 days and it isn't helping your pain, please make an appointment in the clinic with your nurse practitioner (NP) or physician's assistant (PA). We cannot make changes to medication or prescriptions over the phone.
If you have symptoms such as hives or trouble breathing, stop taking the medicine and call 911. Less serious side effects such as nausea, increased tiredness or mild dizziness usually get better within a few days. If they do not, please schedule an appointment with your NP or PA.
You may be asked to bring your unused medication to the clinic appointment. You will be given information on how to safely dispose of your medications.
You are responsible for your medication and making sure it is filled on time. Refills can only be provided during office hours of 8 am to 4:30 pm. If you need a refill of non-narcotic medications, please call your pharmacy. For narcotic or opioid medication refills, call 651-232-5354 and leave a message on your provider line including the following information: your first and last name name (including spelling), the medication you need, and if you want the prescription mailed or picked up. Please allow three days notice for prescriptions to be picked up, and allow seven days notice if the prescription is to be mailed. If you want the prescription mailed, please leave the mailing address. Opioid prescriptions are mailed directly to your pharmacy.
The after hour number for the on-call doctor is 763-537-6000. For emergencies, call 911.
If your test was ordered through HealthEast, we will discuss results with you during your next clinic visit. If your primary care clinician ordered the test, please contact that office for results.
Tell your provider about your symptoms at your next scheduled visit. If you do not have a scheduled appointment, call to schedule the next available appointment at 651-232-5354.
If you received a therapeutic injection using local anesthetic (numbing medication) and a steroid, it might take three to seven days for the steroid to work. If you received only numbing medicine, this is a diagnostic injection, and the pain might return when the numbing medicine wears off. Sometimes pain is not relieved with one injection. Your clinician may recommend additional injections. For steroid injections, we recommend waiting two to four weeks between injections. If you have any additional questions or concerns, please call us at 651-232-5354.
Discuss any questions or concerns with your provider at your clinic visit. We suggest you come with a list of your questions in preparation for your appointment.
All procedures scheduled in advance are submitted to your insurance company before the procedure. If medications are not covered by insurance, your pharmacy should fax us at 651-232-5217 to start the prior authorization process with your insurance company. If a prior authorization is needed, this may take one to two weeks to complete. We will notify your pharmacy once we receive the decision.
If you need copies of your records, you need to sign a release of information form and provide complete information about where to send the records, including the address. Click here for the release of information form.
Forms typically require two weeks to process and need to be discussed with your provider at your clinic visit to clarify documentation requirements and responsibility. If you have an attorney or third party requesting forms or a letter, the request needs to come from the attorney's or third party's office in writing.
Contact HealthEast Pain Center
We'll design a program specifically for you.
Procedures are performed on an outpatient basis, allowing you to keep a regular daily routine. | medical |
https://indueseasonmidwifery.wordpress.com/2017/02/06/postdates-pregnancy-what-are-we-waiting-for/ | 2018-07-15T18:43:59 | s3://commoncrawl/crawl-data/CC-MAIN-2018-30/segments/1531676588961.14/warc/CC-MAIN-20180715183800-20180715203800-00191.warc.gz | 0.928478 | 1,390 | CC-MAIN-2018-30 | webtext-fineweb__CC-MAIN-2018-30__0__200388600 | en | The following is written to outline some points of consideration regarding pregnancies progressing beyond 42 weeks in length.
Postdates pregnancies are often treated as conditions of absolute risk and result in much intervention. While interventions may be required in specific cases, induction of labor is commonly justified by referring to unreliable means of assessing gestational length. After this classification, labor is often induced with aggressive methods which cause undue stress on the unborn, while little consideration is given to equally-effective and minimally invasive natural methods.
It has been discovered that as many as half of “postdates” women are really at term.
Our dating methods and definition of the average length of pregnancy could stand to be reconsidered. It has been discovered that the average gestational length exceeds 280 days. Also, “ultrasound dating has a margin of error greater than dating by LMP.” (p. 186) If both the methods for determining age and the commonly-accepted “average” are both highly innaccurate, we are subjecting women to unnecessary stress by implying that they are outside the realm of normal when, in fact, they are experiencing a very normal pregnancy.
While ultrasound dating may be more accurate when performed between 6 and 12 weeks menstrual age, many obstetricians are not “trained to do or interpret sonograms and over 70% were performed by their assistants”. This is a possible correction within the system which has not been taken into practice. Thus, “components of the biophysical profile will continue to be measured against equally poorly validated fetal surveillance tests.”
- Even in cases of postmaturity, induction may pose a greater risk than any concerns related to the fetus’ gestational age.
“…There is absolutely no study, no evidence whatsoever, that routine induction at any gestational age improves perinatal outcome.” It has been proven that induction and augmentation may increase chance of infection, fetal stress, etc., [4, 11] and the findings of a study comparing early versus late induction were: “Paradoxically, induction succeeds best in women with ripe cervixes, but these are the women most likely to begin labor shortly. If the goal is preventing postmaturity syndrome, these women may not need induction. ‘[W]e now postpone the induction of labor in post-term cases, as the risk in monitoring the natural course, certainly up to day 308, seems minimal.’”
This tells us something very important. When inductions “fail” or do not succeed to induce labor within OUR time frame, it is safe to assume that the mother’s body is simply not responding because the time is not right. If one had never intervened, then, labor and birth would proceed at the rates which were intended in the first place.
Tests, such as the antepartum non-stress test (NST) are known to have a 40-80% false-positive rate. The conditions for which it screens are largely incurable, which gives one cause to wonder what the exact advantage is of a test with such a high false-positive rate which “can lead to undue psychological strain on the woman and her family, unnecessary intervention, and possible iatrogenic problems from the intervention.”
- The safest option is to wait, followed by the option of using more natural means of inducing labor.
Rather than contribute to anxiety, discontentment, and possibly danger to the mother and baby, care providers ought to watch and wait, knowing that indications for induction/augmentation will present themselves if they are truly necessary. Natural induction methods are to be considered first, although resulting stress on the fetus cannot be dismissed.
“In the absence of signs [of growth retardation] and in otherwise uncomplicated pregnancies, the safest management of prolonged pregnancy is to await the spontaneous onset of labor.”
It has been proven that:
- Nipple stimulation ripens the cervix and shortens pregnancy [8-9]
- Membrane stripping does not affect the mode of delivery when used to shorten labor [5-7]
From these findings, we may conclude that many a healthy mother carrying a pregnancy lasting longer than 42 weeks may do so more safely under limited management without increased risk to her or her child. If it becomes necessary, intervention ought to begin in its most minimal form, progressing to more invasive means with the correct indications and with full disclosure of the risks to the parents.
- Shearer MH and Estes M. A critical review of the recent literature on postterm pregnancy and a look at women’s experiences. Birth 1985;12(2):95-111.
- Nichols CW. Postdate pregnancy. Part I. A literature review. J Nurse-Midwif 1985a;30(4):222-239.
- Schutte MF et al. Management of premature rupture of membranes: the risk of vaginal examination to the infant. Am J Obstet Gynecol 1983;146(4):395-400.
- Sims ME and Walther FJ. Neonatal morbidity and mortality and long-term outcome of postdate infants. Clin Obstet Gynecol 1989;32(2):285-293.
- Satin AJ and Hankins GD. Induction of labor in the postdate fetus. Clin Obstet Gynecol 1989;32(2):269-277.
- McColgin Swet al. Stripping membranes at term: can it safely reduce the incidence of post-term pregnancies? Obstet Gynecol 1990;76(4):678-680.
- El-Torkey M and Grant JM. Sweeping of the membranes is an effective method of induction. Br J Obstet Gynaecol 1992;99(6):455-458.
- Elliott JP and Flaherty JF. The use of breast stimulation to prevent postdate pregnancy. Am J Obstet Gynecol 1984;149(6)628-632.
- Salmon YM, et al. Cervical ripening by breast stimulation. Obstet Gynecol 1986;67(1)21-24.
- Gregor CL, Paine LL, and Johnson TR. Antepartum fetal assessment. A nurse-midwifery perspective. J Nurse Midwifery 1991;36(3):153-167.
- Augensen K et al. Randomised comparison of early versus late induction of labour in post-term pregnancy. Br Med J 1987;294:1192-1195. (Norway)
- Obstetric Myths Versus Research Realities, Henci Goer | medical |
https://farmacja.cm.uj.edu.pl/en/departments/department-of-pharmacokinetics-and-physical-pharmacy/5344-2/ | 2023-02-06T14:59:12 | s3://commoncrawl/crawl-data/CC-MAIN-2023-06/segments/1674764500356.92/warc/CC-MAIN-20230206145603-20230206175603-00782.warc.gz | 0.864472 | 291 | CC-MAIN-2023-06 | webtext-fineweb__CC-MAIN-2023-06__0__146182483 | en | We recommend our services and invite to cooperate on:
- Pharmacokinetic studies of drug candidates in various animal species (mouse, rat, rabbit) following intravenous, intragastric, subcutaneous (including osmotic pumps) and intraperitoneal administration with the possibility of multiple sampling from the single animal (jugular vein cannulation)
- Allometric scaling and dose selection for clinical trials
- Evaluation of binding of new compounds to plasma proteins by means of equilibrium dialysis and ultrafiltration with mathematical data analysis (Scatchard method)
- Assessment of metabolism and transport of new compounds using isolated, perfused organs
- Basic physicochemical and kinetics studies of drug release in a flow-through apparatus as well as data analysis using mathematical models.
- Determination of drug (drug candidates) and their metabolites concentrations in blood, urine and tissue homogenates using HPLC analytical methods with DAD, fluorimetric and electrochemical detection as well as LC – MS/MS technique.
- Chromatographic separation and quantitative analysis of enantiomers in biological matrices
- Monitoring of drug and metabolite concentrations in blood and body fluids in patients
- Pharmacokinetic and pharmacokinetic-pharmacodynamic (PK/PD) data analysis using professional software | medical |
http://zarnab.com.pk/endeavor-college-of-natural-heath/ | 2024-03-03T22:00:32 | s3://commoncrawl/crawl-data/CC-MAIN-2024-10/segments/1707947476399.55/warc/CC-MAIN-20240303210414-20240304000414-00234.warc.gz | 0.901394 | 166 | CC-MAIN-2024-10 | webtext-fineweb__CC-MAIN-2024-10__0__32715812 | en | Providing the highest standard of education, the most informed curriculum and a nation-wide campus footprint, Endeavour is Australia’s largest provider of Higher Education to the complementary medicine sector.We provide Bachelor of Health Science degrees in Naturopathy, Nutritional and Dietetic Medicine, Acupuncture and Myotherapy, and an Honours Program in these disciplines, as well as a fully online Bachelor of Complementary Medicine.At Endeavour College of Natural Health (formerly known as the Australian College of Natural Medicine) we are committed to the future and success of Natural Health both in Australia and internationally.
- Bachelor of Health Science (Naturopathy)
- Bachelor of Health Science (Nutritional and Dietetic Medicine
- Bachelor of Health Science (Acupuncture)
- Bachelor of Health Science (Myotherapy) | medical |
https://thecongressmusic.com/exceptional-care-for-little-smiles-unveiling-the-top-rated-pediatric-dentist/ | 2023-09-29T13:21:08 | s3://commoncrawl/crawl-data/CC-MAIN-2023-40/segments/1695233510516.56/warc/CC-MAIN-20230929122500-20230929152500-00373.warc.gz | 0.916124 | 1,357 | CC-MAIN-2023-40 | webtext-fineweb__CC-MAIN-2023-40__0__281002503 | en | When it comes to the dental health of your child, finding the right pediatric dentist is crucial. A top-rated pediatric dentist can provide exceptional care and create a positive dental experience for your little one. If you’re seeking the best dental care for your child in Las Vegas, look no further than the Top Rated Pediatric Dentist in Las Vegas. In this article, we will unveil the qualities and services of a top-rated pediatric dentist, highlighting their expertise, nurturing approach, and the impact they can have on your child’s oral health. Join us as we explore the exceptional care provided by a top-rated pediatric dentist for little smiles.
The Qualities of a Top Rated Pediatric Dentist
A top-rated pediatric dentist possesses a unique set of qualities that contribute to their excellence in caring for little smiles. Here are some key qualities to look for:
1. Extensive Pediatric Expertise
A top-rated pediatric dentist has specialized training and extensive experience in treating children’s dental needs. They understand the unique growth and development of children’s teeth and jaws, allowing them to provide specialized care tailored to their young patients.
2. Gentle and Nurturing Approach
A top-rated pediatric dentist creates a nurturing environment that helps children feel comfortable and at ease during dental visits. They employ a gentle approach and use child-friendly techniques to minimize anxiety and build trust with their young patients.
3. Excellent Communication Skills
Effective communication is crucial in pediatric dentistry. A top-rated pediatric dentist communicates clearly and compassionately with both children and their parents. They explain procedures in a way that children can understand, answer questions patiently, and provide oral health education to parents.
4. Behavior Management Techniques
Managing the behavior of young patients is a vital aspect of pediatric dentistry. A top-rated pediatric dentist possesses excellent behavior management skills, using positive reinforcement, distraction techniques, and age-appropriate explanations to create a positive dental experience for children.
5. Advanced Facilities and Technology
A top-rated pediatric dentist invests in advanced facilities and utilizes modern dental technology to provide the highest level of care. They stay updated with the latest advancements in pediatric dentistry to offer their patients the most effective and comfortable treatments available.
6. Focus on Preventive Care
Preventive care is a key component of pediatric dentistry. A top-rated pediatric dentist places a strong emphasis on preventive treatments such as dental cleanings, fluoride applications, dental sealants, and nutritional guidance. They work closely with parents to educate them on oral hygiene practices that promote optimal oral health.
Services Provided by a Top Rated Pediatric Dentist
A top-rated pediatric dentist offers a range of services to meet the unique dental needs of children. Here are some common services provided:
1. Dental Examinations and Cleanings
Regular dental examinations and cleanings are essential for maintaining good oral health. A top-rated pediatric dentist conducts thorough examinations, checking for tooth decay, gum disease, and other dental issues. They also perform professional cleanings to remove plaque and tartar buildup.
2. Dental Sealants
Dental sealants are a preventive treatment that involves applying a thin, protective coating on the chewing surfaces of the back teeth. This helps prevent tooth decay by sealing out food particles and bacteria from the deep grooves and pits of the teeth. A top-rated pediatric dentist can apply dental sealants to help protect your child’s teeth from cavities.
3. Fluoride Treatments
Fluoride treatments are an effective way to strengthen the tooth enamel and prevent tooth decay. A top-rated pediatric dentist can apply fluoride treatments to your child’s teeth, helping to protect them from acid attacks and promoting overall oral health.
4. Restorative Treatments
In the event of dental issues such as cavities or tooth damage, a top-rated pediatric dentist can provide restorative treatments. This may include dental fillings, dental crowns, or other procedures aimed at restoring the form and function of the affected teeth.
5. Orthodontic Evaluations
A top-rated pediatric dentist can evaluate the alignment and growth of your child’s teeth and jaws. They can identify any orthodontic issues early on and provide appropriate guidance or referral to an orthodontic specialist if necessary.
6. Dental Education and Guidance
A top-rated pediatric dentist recognizes the importance of dental education and provides guidance to both children and parents. They offer advice on proper brushing and flossing techniques, discuss the importance of a balanced diet for oral health, and address any concerns or questions related to children’s dental care.
Choosing a Top Rated Pediatric Dentist
Selecting a top-rated pediatric dentist for your child is an important decision. Here are some factors to consider:
1. Recommendations and Reviews
Seek recommendations from trusted sources, such as family, friends, or your child’s pediatrician. Read online reviews and testimonials to gain insights into the experiences of other parents and their children with different pediatric dentists.
2. Qualifications and Credentials
Research the qualifications and credentials of the pediatric dentists you are considering. Look for dentists who have completed specialized training in pediatric dentistry and are members of reputable dental associations.
3. Communication and Comfort
Schedule a consultation or initial visit with the pediatric dentist to assess their communication style and the comfort level they create for your child. Pay attention to how well they engage with your child and address any concerns or questions you may have.
4. Office Environment
Visit the dental office to observe the environment and facilities. Ensure that the office is child-friendly, clean, and equipped with modern technology. A welcoming and comfortable environment can contribute to a positive dental experience for your child.
5. Location and Convenience
Consider the location of the dental office and the convenience it offers for regular visits. A conveniently located pediatric dentist can make it easier to maintain consistent dental care for your child.
Choosing a top-rated pediatric dentist is essential for ensuring exceptional care for your child’s dental health. A top-rated pediatric dentist possesses specialized expertise, a nurturing approach, and a commitment to providing the highest level of care for little smiles. By focusing on preventive care, utilizing advanced technology, and emphasizing communication and comfort, these dental professionals create a positive dental experience that sets the foundation for a lifetime of optimal oral health. Take the time to research and select a top-rated pediatric dentist who can deliver exceptional care and help your child maintain a healthy, beautiful smile. | medical |
http://impactinnovation2014.womensresearch.ca/ | 2021-12-08T15:47:47 | s3://commoncrawl/crawl-data/CC-MAIN-2021-49/segments/1637964363515.28/warc/CC-MAIN-20211208144647-20211208174647-00516.warc.gz | 0.948123 | 7,888 | CC-MAIN-2021-49 | webtext-fineweb__CC-MAIN-2021-49__0__17248642 | en | MESSAGE FROM THE CEO AND VP RESEARCH
At Women’s College Research Institute (WCRI), we are asking the questions that really matter. Our internationally recognized scientists lead innovative and focused research programs that deliver essential health system solutions and are designed to improve the health of women and to target chronic conditions affecting women across their lifespan.
By collaborating with other scientists internationally and engaging with diverse groups, we are reaching out to the world and transforming care through science. Our research enhances prevention strategies, improves treatment models, and transforms how care is delivered.
In WCRI’s 2014 Impact + Innovation Report, we demonstrate how our research is being used to support services for women with mental illness, to empower women in managing their cancer risk, to create standards that are being adapted internationally to increase the value and quality of research, and to shape international guidelines for chronic diseases.
As part of our dedication to disseminate knowledge on women’s health, we created Women’s Xchange. Through this knowledge translation and exchange centre, we are leading a provincial initiative to make sex- and gender-based analysis part of all research studies and to provide the tools to make this happen. Our goal is to ensure that all studies will provide a unique perspective on the distinctive aspects of women’s health. And when we learn about women, we also learn about men. Promoting a gender-sensitive approach to research improves health and quality of life for all.
Much of our impact can be measured in the way we share our knowledge with the world. Our scientists continue to be exceptionally productive, publishing their findings in some of the most influential journals internationally. In the past year, our scientists published more than 250 peer-reviewed publications, a 60 per cent increase from the last five years, and the global media coverage of our science shows just how important and relevant our work is to the world. Our growing leadership and capacity is also reflected in our steadfast fiscal growth – our external research funding has grown more than 25 per cent over the last year and more than 60 per cent over the last five years – and in a challenging funding environment.
Most of our scientists are also clinicians – their research is informed by their clinical practice and can be directly translated into improving clinical care locally and beyond. This will be enhanced when the research institute moves into Women’s College Hospital’s new facility, which will be completed in 2015. This union will bring our scientists even closer to the clinics, programs and patients that they are impacting. The iconic pink cube at the centre of this new state-of-the-art facility will become a space that we will use to exchange ideas and continue to grow our groundbreaking research and reach.
DEVELOPING INTERVENTIONS TO HELP PREGNANT AND POSTPARTUM WOMEN MANAGE MENTAL ILLNESS
Untreated depression in pregnancy and postpartum can have harmful effects for mothers and their infants and families.
That’s why Cindy-Lee Dennis, PhD, and Dr. Simone Vigod are working together to better understand depression in pregnancy and postpartum and to develop innovative, accessible treatment interventions to help manage it. Their work has attracted remarkable funding and international media attention and is advancing mental health services for women in Ontario and beyond.
Dennis currently holds the Shirley Brown Chair in Women’s Mental Health Research at Women’s College Hospital (WCH). The chair – a partnership between WCH, the Centre for Addiction and Mental Health, and the University of Toronto – was created by a community-based fundraising campaign honouring a young lawyer who succumbed to severe depression.
“If left untreated, depression in pregnancy or the postpartum period can have significant negative effects on child development that can last into adulthood,” says Dennis. “My program of research focuses on developing and evaluating interventions that improve maternal health and enhance infant outcomes.”
Dennis recently evaluated, for the first time, telephone-based interpersonal psychotherapy by trained nurses for the treatment of postpartum depression. The results showed that therapy can be effectively administered to depressed mothers across Canada.
“We know that interpersonal psychotherapy is an effective treatment for postpartum depression and mothers often prefer it over medication,” says Dennis. “However in its usual face-to-face format, women in rural and remote areas often do not have access to it. If the telephone format is implemented, all women could receive this effective treatment at times that are convenient for them.”
Dennis was invited to discuss this trial with health policy-makers in New York City, as they are considering implementing the intervention for depressed mothers across their city.
Dennis is also conducting a study to examine the onset, course and consequences of postpartum depression in mothers and fathers.
“This study will produce urgently needed knowledge that will inform the development of effective postpartum depression interventions for both parents,” she says.
"While antidepressant drugs are the standard of care for moderate to severe depression, many pregnant women are hesitant to take the drugs; however, these women are also aware of the risks of untreated depression. They have a difficult decision to make about their treatment during pregnancy."
– Dr. Simone Vigod
In 2012, Dennis presented the inaugural Clinician-Scientist Award from the Shirley Brown Chair program to Dr. Vigod, a psychiatrist in the reproductive life stages program at WCH and scientist at Women’s College Research Institute. One of Dr. Vigod’s areas of research is answering important questions about how to better manage depression in pregnancy.
“Current treatments for depression in pregnancy are less than ideal,” says Dr. Vigod. “While antidepressant drugs are the standard of care for moderate to severe depression, many pregnant women are hesitant to take the drugs; however, these women are also aware of the risks of untreated depression. They have a difficult decision to make about their treatment during pregnancy.”
To address this issue, Dr. Vigod is exploring the use of non-drug treatments for depression in pregnancy. This year she will launch a pilot study to evaluate an innovative treatment – transcranial direct current stimulation – for moderate to severe depression in pregnant women.
“If effective, this would offer women an alternative to medication,” says Dr. Vigod.
RESEARCH PARTNERSHIPS THAT STRENGTHEN THE REACH OF HEALTH SERVICES
Gender-based violence is believed to be the most widespread human rights violation of our time, seriously harming women, families and communities across the globe.
"According to the World Health Organization, one in three women will experience physical or sexual violence, and we know that this type of violence has a detrimental effect on the mental, sexual and reproductive health of women and girls that can sometimes be fatal," says Janice Du Mont, EdD, a scientist at Women’s College Research Institute (WCRI).
Du Mont’s research is focused on making the world a better place for women and girls. She leads an interdisciplinary research program that examines the impact of gender-based violence on women’s health. Her work has focused largely on evaluating hospital-based programs and policies in order to improve health service delivery to victims of sexual assault and interpersonal violence in Ontario and abroad.
"Much of my work could not have been possible without my partnership with the Ontario Network of Sexual Assault and Domestic Violence Treatment Centres," says Du Mont.
The Ontario Network of Sexual Assault and Domestic Violence Treatment Centres is made up of 35 hospital-based centres that provide emergency care to victimized individuals. The first centre was established at Women’s College Hospital (WCH) in 1984, and since then, the network has grown to include hospitals across the province. Sheila Macdonald, MN, is the provincial coordinator of the network and clinical manager of the centre based at WCH.
"My close collaboration with Sheila and the network is allowing us to do research that addresses the complex needs of victims of violence and provides the basis for improving and expanding forensic and healthcare services for these individuals," says Du Mont.
Du Mont and Macdonald have conducted several large-scale multi-centre studies to develop, implement and evaluate programs of sexual assault care. Their findings are effectively shaping health policy and practice; for example, recommendations from a study designed to address the unmet needs of drug-facilitated sexual assault victims led to new provincial standards for sexual assault care. This research received widespread global media attention. Another province-wide multi-centre study resulted in a policy to provide free-of-charge HIV post-exposure prophylaxis to sexual assault victims in Ontario.
"We are able to make these significant strides in advancing care and service delivery because we involve important stakeholders in the work we do," says Du Mont. "This includes policy-makers, healthcare providers, community organizations, and representatives from the legal and law enforcement sectors."
"Much of my work could not have been possible without my partnership with the Ontario Network of Sexual Assault and Domestic Violence Treatment Centres."
– Janice Du Mont, EdD
Currently, Du Mont and Macdonald are collaborating with elder abuse experts to develop an elder abuse intervention that will eventually be implemented and evaluated at Ontario’s Sexual Assault and Domestic Violence Treatment Centres. In a coordinated and integrated manner, this intervention will address the complex functional, social, forensic and medical needs of older adults who have been abused.
"Elder abuse is a growing issue in the world’s aging population, particularly for women," says Du Mont. "We hope that our intervention will prevent or reduce the use of emergency services and other health services by victimized older adults."
USING VIRTUAL SUPPORT SYSTEMS TO IMPROVE WOMEN’S MENTAL HEALTH AND WELL-BEING
Women who have been treated for gynecological cancer often struggle with concerns about body image, sexuality and self-esteem. And because these concerns are personal and sensitive, many women feel uncomfortable talking about their challenges with their doctor and close ones.
Helping these women has been an area of interest for Catherine Classen, PhD, senior scientist at Women’s College Research Institute, as well as academic lead of the Trauma Therapy Program, director of the Women’s Mental Health Research Program, and clinical psychologist at Women’s College Hospital.
Classen and her team developed a much-needed private, online support group to help reduce psychosexual distress for women who have been treated for gynecological cancer. The intervention, called GyneGals, is currently being trialled across North America with funding from the Canadian Institutes of Health Research (CIHR) and Ovarian Cancer Canada.
"The idea behind GyneGals was to create a comfortable space for women to discuss how gynecological cancer has changed the way they feel about themselves, their relationships and their sexuality, and to learn new ways for coping," says Classen. "And because GyneGals is online, it’s accessible to women, no matter where they live."
GyneGals is a 12-week intervention provided in a discussion board format, where women can contribute at any time and mental health professionals participate as moderators. There are also two moderated chat sessions. Radiation oncologist Dr. Lisa Barbera of Odette Cancer Centre and surgical oncologist Dr. Sarah Ferguson of Princess Margaret Hospital participate in the second chat session to address concerns or questions.
"In my experience, cancer patients are reticent to talk about sexual issues in face-to-face groups. Offering online support groups for gynecological cancer patients addresses an unmet need."
– Catherine Classen, PhD
"Online groups can be particularly helpful for conditions that are highly sensitive and private, potentially stigmatizing, or so rare it is virtually impossible to get a group together," says Classen. "In my experience, cancer patients are reticent to talk about sexual issues in face-to-face groups. Offering online support groups for gynecological cancer patients addresses an unmet need."
Although the trial is still ongoing, many women have already said that GyneGals provided them with useful information and tips for coping and helped them realize that their challenges are not unusual.
If the intervention proves to be effective, the long-term goal is to make it widely available to women.
"We hope to reach as many women as possible with GyneGals and help support them in their journey towards improved health and well-being," says Classen.
SUPPORTING COMMUNITY-BASED RESEARCH TO IMPROVE THE HEALTH OF WOMEN AND GIRLS IN ONTARIO
At Women’s College Research Institute (WCRI), we believe that investing in community-based women’s health research has the potential to improve the health and well-being of all women in Ontario.
This vision sparked the creation of Women’s Xchange, a knowledge translation and exchange centre based at Women’s College Hospital (WCH) and funded by the Ministry of Health and Long-Term Care. By promoting the development of women’s health research across the province, the centre aims to create a more equitable and sustainable healthcare system for women and all Ontarians.
"Women’s Xchange is really about reaching out to researchers, trainees and community partners, and connecting and supporting them to make women’s health a priority in research," says Dr. Paula Rochon, vice-president of research at WCH and lead of Women’s Xchange. "It leverages the 100 years of history and expertise housed at WCH to grow momentum in women’s health research throughout Ontario."
Last year, Women’s Xchange launched the $15K Challenge, a competition that provides funding to researchers and community organizations across Ontario to conduct research to advance the health of women and girls. The initiative allows community groups to come forward with research ideas and partner with academics to study important questions. Ultimately, these projects will benefit local communities and some may be further developed provincially and beyond.
"We know that women’s health is influenced by many factors beyond traditional healthcare," says Robin Mason, PhD, a community-based researcher at WCRI and scientific lead of Women’s Xchange. "The $15K Challenge is not only an opportunity for us to mentor and empower community organizations in conducting research, but it also has the potential to improve the health of local communities."
"The $15K Challenge is not only an opportunity for us to mentor and empower community organizations in conducting research, but it also has the potential to improve the health of local communities."
– Robin Mason, PhD
Women’s Xchange developed a community-based research application and review process for the $15K Challenge and invited groups across Ontario to submit projects that would identify unmet needs within a community, explore or test solutions to problems, or better understand factors that influence women’s health.
In its first three rounds of competition, Women’s Xchange received 71 proposals for small-scale projects initiated by community organizations, as well as 17 for large-scale projects that would involve collaborations between community and academic organizations. In total, 24 small projects and two large projects were funded.
"The research funded by the $15K Challenge will address a number of women’s health issues across a broad range of populations and locations," says Mason. "Through these projects, we will learn more about how to improve the health of Ontario’s tremendous diversity of women."
EMPOWERING WOMEN TO MANAGE THEIR CANCER RISK
The Familial Breast Cancer Research Unit at Women’s College Research Institute (WCRI) is a world leader in the study of inherited cancers. Led by Dr. Steven Narod, a Tier 1 Canada Research Chair at Women’s College Hospital (WCH), the unit has become internationally recognized for identifying effective strategies to prevent and manage breast and ovarian cancer, particularly in women and families with an inherited BRCA1 or BRCA2 mutation.
The BRCA1 and BRCA2 genes produce proteins that help repair DNA; but when the genes are mutated, the proteins don’t function normally and increase a woman’s risk of developing breast and ovarian cancer. Dr. Narod and his team have the world’s largest bio-bank of samples from BRCA mutation carriers (in collaboration with over 70 centres across the globe), and they are using this resource to better understand how BRCA mutations shape cancer risk and prognosis in women.
In the past year, the team has published several high-profile studies that may strengthen the recommendation for a number of cancer management strategies. A study by Amy Finch, PhD, a postdoctoral fellow working with Dr. Narod, demonstrated the clear benefit of preventive removal of the ovaries and fallopian tubes on reducing overall cancer risk and mortality in women with BRCA mutations. Kelly Metcalfe, PhD, an adjunct scientist at WCRI, found that bilateral mastectomy may be an effective first-line treatment for BRCA mutation carriers with early-stage breast cancer. And Joanne Kotsopoulos, PhD, a scientist at WCRI, showed that the use of oral contraceptives at a young age increases the risk of breast cancer in BRCA1 carriers and should be avoided.
"Our team’s work is benefiting women of all ages and providing accessible prevention and management strategies that women and clinicians around the world can use," says Dr. Narod. "Many of our findings also inform the genetic testing and counselling services we provide at our own unit to families with BRCA mutations."
The Familial Breast Cancer Research Unit is also working to uncover new genetic markers that have a role in cancer risk and mortality. Using the latest technology, Dr. Mohammad Akbari, scientist at WCRI, is leading the team’s state-of-the-art laboratory at WCH to identify new genetic mutations that may impact cancer risk and survival.
"Our research studies demonstrate, time and time again, the importance of providing genetic testing for women at the time of cancer diagnosis and even earlier in their lives."
– Dr. Steven Narod
In addition to conducting world-class cancer genetics research, Dr. Narod and his team are continuously striving to increase global access to cancer genetic testing. The team’s laboratory was the first to offer rapid comprehensive genetic testing for BRCA mutations at the research level in Canada. Since then, the unit has been actively involved in enabling other countries to initiate their own cancer genetics screening programs. For instance, Dr. Narod and his team have provided genetic testing infrastructure and training for physicians and scientists in the Bahamas, so that all women on the islands can be eligible for BRCA testing. The unit is following this model to do the same in other countries including Brazil, Iran, Mexico and Vietnam.
And here in Ontario, Dr. Narod and Metcalfe have re-launched the world’s only cancer genetic testing program for Jewish women. As part of the study, Jewish women in Ontario are being offered free genetic testing for the common BRCA genetic mutations found in the Ashkenazi Jewish population.
"Our study on Jewish women will help identify those with a genetic predisposition to developing cancer who might otherwise not come to the attention of the medical community and receive the preventive care and screening that might benefit them," says Metcalfe, who is leading the study with Dr. Narod.
"Our research studies demonstrate, time and time again, the importance of providing genetic testing for women at the time of cancer diagnosis and even earlier in their lives," says Dr. Narod. "Knowing whether a woman has a BRCA mutation will help guide prevention and treatment decisions and improve the health and longevity of women around the world."
IMPROVING QUALITY AND EFFICIENCY IN MEDICAL RESEARCH
Health research has led to significant global health improvements. But experts have made the case that many more important discoveries could be made if the global research community addressed inefficiencies in the way studies are designed, carried out and reported.
This year, Dr. An-Wen Chan, Phelan Scientist at Women’s College Research Institute, co-led a group of experts from Europe, Australia and the United States to publish a series of papers in The Lancet that outlined solutions to reverse these inefficiencies.
"Over one hundred billion dollars of research investment are wasted globally every year," says Dr. Chan. "But much of this waste is avoidable. Our series of papers documents the extent of problems at each stage of health research and proposes far-reaching recommendations to increase value and reduce waste in research."
These recommendations targeted academic institutions, funders, policy-makers, journals, research ethics boards, and regulators – stakeholders who shape how research is conducted.
One of the papers, led by Dr. Chan, put a spotlight on the fact that the research community and healthcare professionals do not have access to complete and unbiased study information.
"Half of all health research is never published," says Dr. Chan. "When studies do get published, access to them is often restricted and costly, and key details are often missing about how well the study was conducted. We need to fix this inaccessibility issue because it not only wastes research and healthcare dollars, but more importantly, it jeopardizes patient health as doctors may unknowingly prescribe ineffective or harmful treatments."
In his paper, Dr. Chan called on stakeholders to implement incentives and standards that will encourage scientists to fully share and report their studies.
"Half of all health research is never published. We need to fix this inaccessibility issue because it not only wastes research and healthcare dollars, but more importantly, it jeopardizes patient health."
– Dr. An-Wen Chan
One initiative already fulfilling this goal is a set of guidelines developed by the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) group to help scientists develop high-quality, detailed clinical trial protocols.
Chaired by Dr. Chan, the SPIRIT group is an international group of trial investigators, journal editors, industry sponsors, ethicists and funders. Their guidelines have received global endorsement by over 25 trial groups, industry sponsors and academic institutions. In addition, over 75 medical journals have introduced policies to encourage scientists to adhere to the SPIRIT guidance, and some countries in Europe have implemented the SPIRIT guidelines nationally.
Dr. Chan is now collaborating with MaRS Innovation to develop a web-based tool that will help researchers develop, format and manage their clinical trial study protocols according to SPIRIT guidelines.
TAPPING INTO SILICON VALLEY TO IMPROVE HEALTHCARE
People with complex chronic diseases frequently transition between hospital care and community care and are not well served by our health system, which is built around institutions and disease conditions.
"As a primary care provider, I see first-hand how my patients with complex needs jump from one specialist to another to manage their health," says Dr. Onil Bhattacharyya, Frigon Blau Chair in Family Medicine Research at Women’s College Hospital (WCH). "Pulling this information together and creating a cohesive plan of care for these patients is challenging. A big question that drives much of my work as a scientist is, how can we organize care so that healthcare providers work together to meet patient needs?"
To address this issue, Dr. Bhattacharyya is co-leading an initiative called BRIDGES (Building Bridges to Integrate Care), a platform funded by the Ontario Ministry of Health and Long-Term Care to select, support and develop new models of innovative, integrative care for people with complex chronic diseases.
"BRIDGES is an incubator that brings together researchers, healthcare providers, policy-makers and community service workers to think about healthcare solutions," says Dr. Bhattacharyya. "We have funded nine new models of care and helped project teams refine and test their model, creating a collaborative environment to help them redesign or expand their idea into a suite of related programs."
Dr. Bhattacharyya is building from this experience to create an incubator at WCH and lead a provincial network called BEACCON (Better Access and Care for Complex Needs), which is funded as part of the Canadian Institutes of Health Research’s Strategy for Patient-Oriented Research.
"A big question that drives much of my work as a scientist is, how can we organize care so that healthcare providers work together to meet patient needs? "
– Dr. Onil Bhattacharyya
Under Dr. Bhattacharyya’s guidance, the incubator will apply methods from the software and design industries – which involve iteratively testing and refining a product or service to find something that works well for users – to develop new models of care for people with complex needs. These methods are about generating new ideas and managing uncertainty.
"Silicon Valley has been a hotbed of disruptive solutions that have delivered waves of products and services based on users’ needs and increased efficiency – something the health system desperately needs," says Dr. Bhattacharyya. "The approaches used by Silicon Valley startups embrace uncertainty and may offer health system solutions better suited to patients with complex chronic diseases."
Dr. Bhattacharyya’s work, focused on quality and innovation, is transforming the way health system research is done. His work has the potential to enable hospitals, institutions and doctors across the province to deliver cost-effective solutions that improve patient experience and outcomes.
VIEWING Anita Benoit, PhD
NEXT Dr. Jacob Udell
Some Aboriginal women are overburdened with stressors like violence, discrimination, stigma and poverty, all of which have contributed to this population’s over-representation in the Canadian HIV and AIDS epidemic.
"The goal of my research is to understand how Aboriginal women living with and without HIV experience and manage stress, so that I can then work with them to develop culturally appropriate, stress-reducing therapeutic interventions that will improve their health and well-being," says Anita Benoit, PhD.
Benoit is a postdoctoral fellow working with Dr. Mona Loutfy, a scientist at Women’s College Research Institute whose research focuses on sexual and reproductive health, stigma and access to care for women with HIV.
To conduct her research, Benoit is collaborating with the Ontario Aboriginal HIV/AIDS Strategy, 2-Spirited People of the 1st Nations, and the Native Women’s Resource Centre of Toronto. Her work is supported by the Canadian Institutes of Health Research and the Alternative Funding Plan Innovation Fund.
"Interventions to promote healthy outcomes and well-being in Aboriginal women typically lack a cultural component and an awareness of the lived experiences of Aboriginal women," says Benoit. "In my research, Aboriginal women’s lived experiences are at the forefront."
Benoit will use methods such as in-depth semi-structured one-on-one interviews and sharing circles to collect data. Her research process will include ceremonies by a spiritual leader, and the impact of stress on well-being will be discussed using a medicine wheel (a symbolic representation of the mental, emotional, physical and spiritual aspects of well-being and wholeness). Once Benoit designs an intervention with and for the women, she will pilot it with the group.
Some of her findings have already been used by the Native Women’s Resource Centre of Toronto to create a space for peer outreach workers to talk about healthy sexuality and HIV prevention with interested individuals.
VIEWING Dr. Jacob Udell
NEXT Dr. Javaid Iqbal
Dr. Jacob Udell, a research fellow at Women’s College Research Institute and cardiologist at Women’s College Hospital, is leading innovative research to improve the heart health of Canadians.
This year, he was awarded the Rising Star Award from the CIHR Institute of Health Services and Policy Research for his novel work on understanding the effect of the flu vaccine on cardiovascular health. One of his recent studies found that the flu vaccine may reduce the risk of heart attack or stroke.
"If the flu vaccine can reduce the risk of cardiac events, these shots could have a considerable impact on cardiac health," says Dr. Udell.
To confirm the effectiveness and safety of the flu vaccine as a therapy for people with heart disease, he is now collaborating with researchers across the United States and Canada to conduct a large clinical trial. He hopes that this trial will explain the mechanism behind how the flu vaccine protects cardiovascular health.
"Hundreds of thousands of people die each year from cardiac causes in North America," says Dr. Udell. "While preventive care involves lifestyle changes and medication, soon we may also be able to tell patients that getting your flu shot may save your life."
Dr. Udell’s other projects include a trial to investigate the metabolic benefits of a new non-invasive laser liposuction technique, as well as a study of the long-term cardiovascular outcomes for women who take fertility therapy. His work has generated national and international recognition and media coverage, leading to his role as a spokesperson for the Heart and Stroke Foundation of Canada.
VIEWING Dr. Javaid Iqbal
"It is well known that immigrant women often face barriers to timely breast screening, putting themselves at risk of being diagnosed with breast cancer at a more advanced stage," says Dr. Javaid Iqbal, a research fellow working with Drs. Paula Rochon and Steven Narod.
"Given the diverse and large immigrant population in Canada, understanding how immigrant status affects breast cancer presentation has been a major area of interest for me."
For his postdoctoral fellowship, Dr. Iqbal is linking multiple databases in Ontario to compare breast cancer stage at diagnosis between immigrant women and the general population in Ontario.
"Diagnosing breast cancer at an earlier stage significantly increases a woman’s chances of survival," says Dr. Iqbal. "I hope that my research findings will help the scientific community to understand biological differences in breast cancer among multiethnic immigrants, as well as assist policy-makers to create awareness programs and screening policies to increase early detection in the most vulnerable ethnic groups among immigrants."
Once his fellowship is complete, Dr. Iqbal will start a master’s, funded by the Canadian Institutes of Health Research, to evaluate the impact of recent and subsequent pregnancies on breast cancer mortality.
Young women diagnosed with breast cancer often ask about subsequent pregnancy and its possible impact on breast cancer mortality. Unfortunately, there are no guidelines that define a safe time to get pregnant after breast cancer.
"It is important that we obtain accurate data on the impact of pregnancy on breast cancer, so that health professionals can offer evidence-based guidance to women wishing to have a baby after breast cancer," says Dr. Iqbal.
THIS IS HOW OUR SCIENCE IS TRANSFORMING HOW CARE IS DELIVERED
Our scientists are partnering with other experts in Canada and around the world to lead scientific research that is having a global impact on improving the health of women, advancing care for people with chronic conditions, and delivering much needed health system solutions. Together we are tackling some of the most pressing issues in healthcare today and are inspiring real innovations in patient care globally.
IMPROVING THE HEALTH OF PATIENTS WITH BOTH OSTEOARTHRITIS AND DIABETES
Osteoarthritis is the most common form of arthritis, affecting one in eight Canadians. With no cure, management of the condition focuses on pain relief and preserving mobility.
"Diabetes is particularly common among people with osteoarthritis, given the shared risk factors – aging and obesity – and the negative effects of diabetes on joint tissues," says Dr. Gillian Hawker, a senior scientist at Women’s College Research Institute (WCRI) who focuses on improving access and outcomes of care for people with osteoarthritis.
Dr. Hawker is now collaborating with Dr. Lorraine Lipscombe, director of the Centre for Integrated Diabetes Care at Women’s College Hospital and scientist at WCRI, to understand the relationship between osteoarthritis and diabetes.
"Despite the fact that many people suffer from both conditions, little research has been done to understand how osteoarthritis impacts diabetes outcomes in people with both conditions," says Dr. Hawker.
"For example, physical inactivity due to osteoarthritis leads to poorer fitness and weight gain – does this contribute to poorer outcomes in people with diabetes? And does reduced hand strength and dexterity from hand osteoarthritis affect the ability of people with diabetes to prepare meals and perform glucose monitoring? Currently, we don’t have sufficient evidence about how these common chronic conditions interact. Understanding these relationships will help us to improve the way these patients are cared for."
Drs. Hawker and Lipscombe are conducting a population-based study that will answer important questions about the impact that osteoarthritis disability has on diabetes self-management and complications.
"If there is an association, our study will make a case for targeted screening and enhanced management of osteoarthritis in people with diabetes," says Dr. Lipscombe.
" Despite the fact that many people suffer from both conditions, we don’t have sufficient evidence about how these two common chronic conditions interact."
– Dr. Gillian Hawker
" While prophylactic oophorectomy is recommended for women with a BRCA mutation, the long-term effects on cardiovascular health and quality of life are not well understood."
– Dr. Steven Narod
RESHAPING THE FUTURE FOR WOMEN AT HIGH RISK FOR BREAST AND OVARIAN CANCER
When a woman has a mutation in her BRCA genes, she is at a higher risk of developing breast and ovarian cancer.
Research has long shown that women with a BRCA mutation can decrease their risk of cancer and mortality by surgically removing their ovaries and fallopian tubes. For this reason, doctors often advise women who carry such a mutation to have this procedure.
"While this prophylactic surgery is safe, its long-term effects on cardiovascular and bone health, as well as quality of life, are not well understood," says Dr. Steven Narod, a Tier 1 Canada Research Chair in Breast Cancer at Women’s College Hospital. "We need to do more research so that we can establish clinical guidelines to help keep the young women who opt for this surgery healthy."
Dr. Narod and his postdoctoral fellow Amy Finch, PhD, are doing just that by teaming up with Dr. Paula Harvey, a scientist at Women’s College Hospital who specializes in cardiovascular disease in women.
"When a woman loses ovarian estrogen, it increases her risk for cardiovascular disease, which is the leading cause of death for women," says Dr. Harvey. "Understanding the effects of ovary removal surgery on young women with a BRCA mutation is a priority for this population."
Dr. Narod and Dr. Harvey’s study, funded by the the Canadian Institutes of Health Research, will follow a cohort – the largest of its kind in Canada – of premenopausal women undergoing this procedure.
"We’re hoping that our study will tell us more about how this surgery affects young women in the short and long term, and what doctors should be doing to improve these women’s health and well-being," says Dr. Narod.
ABOUT WCRI - WOMEN'S COLLEGE RESEARCH INSTITUTE
A MESSAGE FROM KATHERINE HAY AND WOMEN’S COLLEGE HOSPITAL FOUNDATION
The innovative work of Women’s College Research Institute (WCRI) is diverse, far-reaching and life-changing. While our reach is extraordinary indeed, so too is the exceptional commitment and generosity of our supporters!
By investing in multidisciplinary women’s health research with an international reach, our donors are partnering to enable the translation of groundbreaking discoveries into new models of clinical care, here and across the globe. Together, we are changing the future of healthcare.
Through the generosity of our donors, Women’s College Hospital Foundation was able to provide funding to support the extraordinary work of WCRI – over $1.3 million this year alone! We are also proud to announce the establishment of an endowed research Chair in Ambulatory Anesthesia, the first of its kind in Canada, created through the partnership and generous support of the department of anesthesia, an individual donor, a corporate donor and an estate gift. The creation of the chair provided the vehicle to establish the Toronto Pain Medicine Institute Network at Women’s College Hospital that will offer patients across the city integrated services and improved wait times.
The enormous ripple effect of the $8.4 million invested by donors since 2006 is best reflected in the inspiring work being carried out by WCRI chairs today. For example, the Shirley Brown Chair in Women’s Mental Health Research, Cindy-Lee Dennis, PhD, is exploring clinical problems facing women with postpartum depression and developing innovative, accessible treatment interventions. Last year, over 49,000 Canadian mothers experienced depression within the first 12 months postpartum, putting at least 80,000 children at risk for adverse outcomes. Work such as Dennis’s not only demonstrates the significant impact of donor support, but also serves as an illustration of how donor contributions can be a catalyst for future breakthroughs.
There is a sense of pride when we reflect on the partnership we have with donors and with WCRI. Our collective commitment to excellence and making a difference has put Women’s College Hospital at the forefront as an international leader in women’s health. Our scientists, physicians, staff, volunteers and – you, our donors – are building the hospital of the future, and changing the future of healthcare. Together, we can!
Endowed chairs, established by our generous supporters: | medical |
https://northatlanticblog.wordpress.com/2017/06/30/the-woman-with-toxic-blood/ | 2019-01-18T18:10:07 | s3://commoncrawl/crawl-data/CC-MAIN-2019-04/segments/1547583660258.36/warc/CC-MAIN-20190118172438-20190118194438-00361.warc.gz | 0.972825 | 1,120 | CC-MAIN-2019-04 | webtext-fineweb__CC-MAIN-2019-04__0__58529508 | en | Around 8:15 p.m. Feb. 19, 1994, a woman named Gloria Ramirez was brought to the emergency room of Riverside General Hospital in Riverside, California while suffering from the effects of cervical cancer. What happened next landed Ramirez a place in the medical history books forever.
Ramirez was wearing shorts and a T-shirt, and although she was still conscious Ramirez could only answer questions with brief and sometimes incomprehensible responses. In terms of her health, she was taking short, rapid breaths and her heart was beating too quickly for its chambers to fill with blood causing her blood pressure to drop. Symptoms such as these are normally seen in elderly patients, and yet Ramirez was 31.
To help her, medical staff gave her Valium, Versed and Ativan to sedate her and lidocaine and Bretylium to slow her heartbeat. Meanwhile, Ramirez was having air forced into her lungs using an Ambu-bag, but nothing was working. Opting to instead try a defibrillator on her heart, the staff removed her shirt and pressed the electrodes to her chest, which is when the staff noticed an oily sheen covering Ramirez’s body and a fruity, garlicky odor which seemed to come from Ramirez’s mouth.
One of the nurses, Susan Kane, drew blood from Ramirez’s right arm, when Kane noticed a chemical smell coming from Ramirez’s blood, similar to ammonia. After a syringe was filled with Ramirez’s blood, both a medical resident and a doctor noticed manila-colored particles floating in the blood.
Then, Kane turned towards the door of the trauma room and began to sway, before someone gently guided her to the floor as she said her face felt like it was burning. As Kane was wheeled away on a gurney, medical resident Julie Gorchynski left the room and sat at a nurse’s desk. Before she could even say how she was feeling, Gorchynski slumped over and was also wheeled away on a gurney. Gorchynski began shaking intermittently and would stop breathing, take a few breaths, then stop breathing again.
In the trauma room, a third person passed out, and then woke up unable to control their limbs. Several other stafff members said they were feeling sick, which prompted the hospital to declare an emergency and move all of the emergency room patients to the parking lot outside the hospital. A skeleton crew of four people remained inside to try and save Ramirez’s life, but despite drugs and electric shocks Ramirez was pronounced dead at 8:50 p.m. Two staff members moved Ramirez’s body to an isolation room; one of whom, Sally Balderas, began retching and felt a burning sensation on her skin.
Overall, 23 of the 37 emergency room staff suffered at least one symptom from being exposed to Ramirez. Kane eventually started flailing and kicking while her skin continued to burn, while Gorchynski (the most severe victim) spent two weeks in intensive care and suffered from apnea, hepatitis, pancreatitis and avascular necrosis, a condition where bone tissue is starved of blood and begins to die.
Around 11 p.m., a Riverside County HAZMAT team arrived at the hospital looking for a volatile toxicant which may still be in the air of the emergency room. In particular, the HAZMAT team was searching for toxins such as hydrogen sulfide, also known as sewer gas, or phosgene, which can be used either to prepare ordinary chemicals or as a chemical warfare weapon. Fortunately, the HAZMAT team found nothing in the air that would indicate what was making people sick.
Unfortunately, the Riverside County Coroner had to perform an autopsy on Ramirez using airtight moon suits in a sealed examining chamber. But several days after taking blood and tissue samples, the Coroner had to seek help from the Forensic Science Center at the Lawrence Livermore National Laboratory.
Ramirez’s sister, Maggie Ramirez Garcia, said he sister was treated like a “toxic monster” and her body wasn’t released to the family until nine weeks later, even though the official cause of death was kidney failure due to cervical cancer. Eventually the Coroner chalked up the mysterious fumes as the “smell of death,” while the California Department of Health Services claimed some of the medical staff had succumbed to mass hysteria.
But what caused Ramirez’s body to become toxic enough to cause an emergency at a hospital and make several medical staff severely ill?
Eventually the Lawrence Livermore National Laboratory determined dimethyl sulfone was present in Ramirez’s blood, which they believed was a sign Ramirez had been using dimethyl sulfoxide (or DMSO), a non-FDA approved anti-inflammatory drug which is believed by some people to be a cure-all. The DMSO may have oxidized into dimethyl sulfone when the doctors gave Ramirez oxygen, and when the doctors drew blood the dimethyl sulfone could have turned into possibly deadly dimethyl sulfate crystals when exposed to the cool air.
Although the Ramirez family had an attorney file a medical malpractice and wrongful death suit against the county, the Riverside County Coroner corroborated the laboratory’s conclusion, saying the crystals in the blood, Ramirez’s body’s oily sheen and the medical staff’s symptoms were all signs of exposure to dimethyl sulfate. | medical |
http://www.myymgroup.com/blankets-and-bgxcgx/bsr-monitoring-dmards-ebcb4c | 2021-03-04T18:21:08 | s3://commoncrawl/crawl-data/CC-MAIN-2021-10/segments/1614178369512.68/warc/CC-MAIN-20210304174506-20210304204506-00246.warc.gz | 0.881103 | 9,035 | CC-MAIN-2021-10 | webtext-fineweb__CC-MAIN-2021-10__0__107222344 | en | Screening for TB should include checking for previous TB exposure and treatment, perform a clinical examination, chest X-ray (CXR) and either a TST or IGRA or both, as appropriate (grade 2C, SOA 98%). RTX may be considered as a first-line biologic option in RA patients with previous malignancy (grade 2C, SOA 90%). RTX or ABA may be considered a first-line biologic in patients with ILD (grade 2C, SOA 84%). Patients should be investigated for potential malignancy if clinically suspected and biologics should be stopped if non-basal cell carcinoma (BCC) malignancy is confirmed (grade 1C, SOA 97%). Patients should remain Ding T, Ledingham J, Luqmani R, Westlake S, Hyrich K, Lunt M, Kiely P, Bukhari M, Abernethy R, Bosworth A, Ostor A, Gadsby K, McKenna F, Finney D, Dixey J, Deighton C; Standards, Audit and Guidelines Working Group of BSR Clinical Affairs Committee; BHPR. This guideline does not cover the following topics: the use of biologic therapy for conditions other than RA, axial SpA (including AS) and PsA; safety in individuals aged <18 years; safety in the context of pregnancy and breastfeeding, as this has recently been covered in the BSR/BHPR prescribing drugs in pregnancy guidelines ; biologics approved by NICE after June 2016 (such as secukinumab and sarilumab) or Janus-kinase inhibitors; and biosimilar preparations of branded biologics; until further clinical data are available, the safety recommendations we propose for originator biologics can be applied to their biosimilar counterparts. Epub 2010 Sep 12. It covers safety recommendations for all biologic therapies approved by the National Institute for Health and Care Excellence (NICE) up to June 2016, for use in all inflammatory arthritides [RA, PsA and axial SpA (SpA) including AS]. Live attenuated vaccines, such as the herpes zoster vaccine, oral polio or rabies vaccine, should be avoided (grade 2C, SOA 99%). Studies to date suggest that though biologic therapy does not appear to have a detrimental effect on HCV infection, it should continue to be used only with caution in such patients, following a risk–benefit decision made with a hepatologist (grade 1C, SOA 96%). 2008 Oct;47(10):1591; author reply 1591. doi: 10.1093/rheumatology/ken322. Copyright © 2020 British Society for Rheumatology. Clipboard, Search History, and several other advanced features are temporarily unavailable. Patients should be provided with education about their treatment to promote self-management (grade 1B, SOA 99%). Patients with an abnormal CXR, previous history of TB or TB treatment should be referred to a specialist with an interest in TB prior to commencing a biologic (grade 2C, SOA 99%). Taylor PC, Balsa Criado A, Mongey AB, Avouac J, Marotte H, Mueller RB. For patients receiving TCZ, i.v. J Clin Med. C.H. DMARDs; NICE CKS, July 2015 (UK access only) Ledingham J, Gullick N, Irving K, et al; BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs. Treatment should be stopped if progressive multifocal leukoencephalopathy develops. No routine monitoring is necessary with apremilast, hydroxychloroquine, mepa- crine or minocycline. Upper Borough Walls Bath. Correspondence to: Christopher Holroyd, Rheumatology Department, University Hospital Southampton, Tremona Road, Southampton, Hampshire, SO16 6YD, UK. The Public Health England recommendations on the use of immunizations in patients on immunosuppressive therapy should be adhered to in patients on biologics. Blood tests should ideally be in the week before i.v. Baseline assessment for all should include (grade 1C SOA 98%): laboratory evaluation of full blood count (FBC), creatinine/calculated glomerular filtration rate (GFR), alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST), albumin, tuberculin skin test (TST) or IFN-γ release assay (IGRA) or both as appropriate, hepatitis B and C serology and a chest radiograph. Patients on biologics who develop symptoms suggestive of TB should receive full anti-TB treatment but may continue with their biologic if clinically indicated after risk–benefit analysis and discussion with a TB expert (grade 2C, SOA 96%). (Also refer to vaccination recommendations while on biologic therapy.). This is presented alongside each recommendation as a percentage. This table sets out the requirements for ongoing monitoring of conventional DMARDs (disease modifying anti-rheumatic drugs) in primary care. Clinicians should be vigilant for progressive multifocal leukoencephalopathy, which has been primarily associated with RTX but has also reported with anti-TNF therapy. Rheumatology Department, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Malaviya AP, Ledingham J, Bloxham J et al. BSR/BHPR guideline for disease-modifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists Rheumatology (Oxford) . BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs Rheumatology (Oxford) . Consider using ETN or ABA as a first line biologic therapy in patients at high risk of infection (grade 2B, SOA 94%). Hence, any rapid fall or consistent downward trend in any parameter warrants extra vigilance. has received sponsorship to attend meetings by Pfizer and UCB and received honoraria for speaking for Eli Lilly. BSR and BHPR rheumatoid arthritis guidelines on safety of anti-TNF therapies. High risk patients (e.g. For patients on immunosuppressive therapy with a normal CXR, a TST is not helpful, as immunosuppression hinders interpretation (grade 2C, SOA 98%). Secondary care health professionals directly involved in the management of patients with inflammatory arthritis. PRESCRIBED DMARDs DURING THE COVID-19 PANDEMIC OUTBREAK Click here to read the full guidance for this patient cohort which also includes advice on the frequency of blood test monitoring of DMARDs in stable patients. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. A.M. has received honoraria for sponsored presentations from MSD, Bristol-Myers Squibb and Roche and received an honorarium from Pfizer for professional services. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Patients should be screened for HBV and HCV infection (grade 1C, SOA 98%). The effect of biologics on pre-malignant conditions remains unclear. When clinical responsibility for prescribing is transferred to general practice, it is important that the GP, or other primary care prescriber, is confident to prescribe the necessary medicines. Br J Clin Pharmacol. Monitoring of DMARDs varies across the country. Summary of DMARDs covered in this guideline and information on whether they require routine monitoring or not. Published by Oxford University Press on behalf of the British Society for Rheumatology. Flint J, Panchal S, Hurrell A et al. Epub 2016 Aug 28. Precautions include adequate screening prior to initiation, vigilant monitoring, especially in higher risk individuals, and an understanding of the implications of certain co-morbidities. The GRADE method was used to assess the quality of evidence and the strength of recommendation . Patients should be assessed for co-morbidities as these may influence biologic choice, including evaluation for respiratory disease and screening for infection (grade 1C, SOA 99%). Management of early rheumatoid arthritis. those at high risk of TB) should be reviewed every 3 months. Indications: (Licensed) RA, ulcerative colitis and Crohn’s disease. ADA and IFX can be considered for the treatment of uveitis, in preference to ETN, which appears to be associated with lower rates of treatment success and has been associated with the development of uveitis. via an advice line (Helpline)] for advice within one working day (grade 1C, SOA 98%). It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. Quick Reference Guide – Ongoing Monitoring Requirements for Disease Modifying Anti-rheumatic Drugs (DMARDs) Rachael Pugh, Prescribing Adviser & Abigail Cowan, Prescribing Advisers, Medicines Management Team, MLCSU | Patients receiving TCZ: a baseline lipid profile is recommended prior to initiation. Any decision to halt treatment should be made in accordance with the guidance in the TCZ SPC (grade 2C, SOA 96%). This guidance has been agreed across all specialities in NHS Highland. If patients develop uveitis while on a biologic, a trial of an alternative biologic could be considered, bearing in mind the latest reported relative risks (grade 1C, SOA 99%). J Assoc Physicians India. There has been recent BSR safety guidance (2016 and 2017) on the use of biologics, which has been incorporated. DMARDs fall into either of … Anti-TNF therapy is relatively contraindicated in patients who have had prior treatment with >150 psoralen and ultraviolet A (PUVA) and/or >350 ultraviolet B (UVB) phototherapy. 2008). Comment on: BSR/BHPR guideline for disease-modifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists. Biologic therapies should not be commenced in patients with clinical signs of, or under investigation for, malignancy (basal cell carcinoma excluded) (grade 1C, SOA 96%). The monitoring requirements and plan should be set out in the written shared care protocol for each patient. Consider switching patients with uveitis currently taking ETN to IFX or ADA (grade 2C, SOA 98%). Disclosure statement: C.R.H. Caution should be exercised in the use of biologics in such patients. Musculoskeletal Care. Patients receiving TCZ should have their serum lipids checked at 3 months, and be treated appropriately if abnormal; they may be checked again thereafter at physician’s discretion (grade 2A, SOA 99%). Specific questions were developed with regards to biologic safety including: What baseline screening is required? 2019 Oct;85(10):2228-2234. doi: 10.1111/bcp.14057. BSR's 'gold standard' clinical guidelines support evidence-based clinical practice in rheumatology. 25 November 2020 Lithium drug monitoring during COVID-19 for stable adult patients Christopher R Holroyd, Rakhi Seth, Marwan Bukhari, Anshuman Malaviya, Claire Holmes, Elizabeth Curtis, Christopher Chan, Mohammed A Yusuf, Anna Litwic, Susan Smolen, Joanne Topliffe, Sarah Bennett, Jennifer Humphreys, Muriel Green, Jo Ledingham, The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis—Executive summary, Rheumatology, Volume 58, Issue 2, February 2019, Pages 220–226, https://doi.org/10.1093/rheumatology/key207. Patients prescribed a biologic (other than TCZ) without concomitant csDMARD (or with csDMARDs that do not require blood test monitoring), should have monitoring blood tests (FBC, creatinine/calculated GFR, ALT and/or AST and albumin every 3–6 months (grade 2C, SOA 97%). Patients receiving csDMARD may require more regular laboratory monitoring (as per BSR/BHPR non-biologic DMARD guidelines, 2017) (grade 2B, SOA 96%). How to Get the Most from Methotrexate (MTX) Treatment for Your Rheumatoid Arthritis Patient?-MTX in the Treat-to-Target Strategy. Prescribing disease-modifying anti-rheumatic drugs (DMARDs) is always part of a shared-care protocol. Rheumatology 2016: 55 Advice and guidance regarding DMARDs Taken from the RCGP Guidance on workload prioritisation during COVID-19. Anti-TNF should be withdrawn if demyelination occurs. Our guidelines grow out of the collaborative efforts of many members and non-members, specialists and generalists, patients and carers. Upper Borough Walls Bath. Biologics covered by this guideline are as follows: anti-TNF inhibitors: infliximab (IFX); etanercept (ETN); adalimumab (ADA); certolizumab pegol; golimumab; anti-CD20: rituximab (RTX); CTLA4-Ig: abatacept (ABA); anti-IL-6 receptor: tocilizumab (TCZ); and anti-IL-12/IL-23: ustekinumab. E-mail: Search for other works by this author on: Rheumatology Department, University Hospitals of Morecombe Bay NHS Foundation Trust, Lancaster, UK, Rheumatology Department, Mid Essex Hospital NHS Trust, Chelmsford, UK, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK, Rheumatology Department, Salisbury District Hospital, Salisbury, UK, Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, UK, National Rheumatoid Arthritis Society, Queen Alexandra Hospital, Portsmouth, UK, Rheumatology Department, Queen Alexandra Hospital, Portsmouth, UK, BSR and BHPR rheumatoid arthritis guidelines on safety of anti-TNF therapies, BSR and BHPR guidelines on the use of rituximab in rheumatoid arthritis, The 2013 BSR and BHPR guideline for the use of intravenous tocilizumab in the treatment of adult patients with rheumatoid arthritis, BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids, The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis, GRADE: an emerging consensus on rating quality of evidence and strength of recommendations, © The Author(s) 2018. If patients develop worsening cardiac failure while on anti-TNF, consideration should be given to stopping therapy if no other explanation for worsening cardiac failure is found following input from a cardiologist (grade 2 C, SOA 99%). For patients receiving RTX, treatment should ideally be stopped 3–6 months prior to elective surgery (grade 2B, SOA 94%). 2008 Jun;47(6):924-5. doi: 10.1093/rheumatology/kel216a. The British Society for Rheumatology (BSR) is the UK's leading specialist medical society for rheumatology and musculoskeletal professionals. HHS RA and psoriatic arthritis (PsA). For permissions, please email: [email protected], This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (. Biologic therapy should be promptly stopped in suspected cases. Biologics may be recommenced after surgery when there is good wound healing (typically around 14 days), all sutures and staples are out, and there is no evidence of infection (grade 1B, SOA 99%). All other authors have declared no conflicts of interest. Patients with HIV receiving anti-TNF therapy require close monitoring of viral load and CD4 count. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. If abnormal, lipid lowering treatment should be initiated as per local guidance (grade 2A, SOA 99%). Abstracts from BSR, EULAR and ACR annual conferences up to and including EULAR 2016 were also included. Dose increases should be monitored by FBC, creatinine/calculated GFR, ALT and/or AST and albumin every 2 weeks until on stable dose for 6 weeks then revert to previous schedule (GRADE 2B, 97%). Although recent data are reassuring, biologics should be used with caution in patients with class III or IV cardiac failure, working closely with a cardiologist (grade 2C, SOA 96%). Using the GRADE approach, the quality of evidence was determined as either high (A), moderate (B) or low/very low (C) reflecting the confidence in the estimates of benefits or harm. Note throughout that, whilst absolute values are useful indicators, trends are also important. Epub 2019 Aug 9. Exceptions/additions to the monitoring schedule for specific DMARDs are included in Table 1 (GRADE 2B and C, 100%). 2017 Jun 1;56(6):865-868. doi: 10.1093/rheumatology/kew479. Clinicians and patients should be aware that the risk of infection increases as serum IgG levels fall below normal (grade 2A, SOA 99%). Accreditation is valid for 5 years from 10 June 2013. Biologic therapies may be continued in patients who develop a BCC that is fully excised, after careful discussion with the patient and a risk–benefit analysis (grade 2C, SOA 97%). Patients should have rapid access to specialist health care for consideration of early treatment (grade 1B, SOA 99%). The use of biologic therapies has transformed the management of inflammatory arthritis, with disease remission becoming an increasingly achievable goal. Blood Monitoring and Prescribing for DMARDs during COVID-19 pandemic Where DMARD use has been successful and stable (> 12 months on treatment, and stable dose for > 6 weeks) consider extending the monitoring interval to up to every 6 months. those at high risk of TB) should be reviewed every 3 months (grade 2C, SOA 94%). (For Frequency of Monitoring Refer to BSR/BHPR guidelines for disease-modifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists. The relative risks of the available agents should be taken into account when selecting which treatment to use (grade 1C, SOA 96%). NIH Once the person is stabilized on treatment, the GP may be asked to: Prescribe and monitor the DMARD. Epub 2008 Aug 1. van Roon EN, van den Bemt PM, Jansen TL, Houtman NM, van de Laar MA, Brouwers JR. Clin Ther. There is a wide variability amongst hospitals within a region on shared care arrangements. Approved: MS April 2019: MS 19.33.1 Page 2 of 18 VERSION SUMMARY OF CHANGES DATE 1.0 Original document (joint with dermatology, Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/, NLM Guidance for Rheumatology patients receiving DMARD, Biologic and / or steroid medication during the Covid-19 outbreak and updated blood monitoring schedule (26032020)This guidance HAS NOT changed. Accompanying each recommendation in this guideline, in brackets, is the strength of recommendation, quality of evidence and strength of agreement. Please enable it to take advantage of the complete set of features! Biologic therapies may be continued in patients at increased risk of, or with, venous thromboembolism (grade 2 C, SOA 99%). DMARDs require regular monitoring for toxicity DMARDs require regular laboratory monitoring for adverse effects. Recommended investigations for commonly used DMARDs are listed in Table 1. R.S. Further details are given in the full guideline . This is the executive summary of The British Society for Rheumatology biologic DMARD safety guidelines in inflammatory arthritis, doi: 10.1093/rheumatology/key208. Pre-existing interstitial lung disease (ILD) is not a specific contraindication to biologic therapy; however, caution is advised in patients with poor respiratory reserve (in whom a significant drop in lung function would be potentially life threatening); in this situation it is advised to work closely with a respiratory physician with a specialist interest in ILD (grade 2C, SOA 99%). The paper discusses the problem of laboratory monitoring in therapy with disease-modifying antirheumatic drugs (DMARDs) and biological agents (BAs) in patients with rheumatoid arthritis (RA). HBV immunization should be considered for at risk patients (grade 2C, SOA 94%). USA.gov. monitoring remains with the hospital or specialist. Biologics should not be initiated in the presence of serious active infections (defined as requiring intravenous antibiotics or hospitalization; not including tuberculosis) (grade 1B, SOA 98%). A comprehensive literature search was undertaken using MEDLINE, Cochrane, PubMed and EMBASE databases with specific search terms. The decision to initiate a biologic should be made in conjunction with the patient/carer and initiated by an expert in the management of rheumatic disease (grade 1C, SOA 99%). Pulmonary function tests should be performed as clinically indicated, usually every 4–6 months (grade 2C, SOA 99%). Close monitoring of serum amino-transaminases and HBV DNA load is recommended in patients with occult or overt HBV infection treated with biologic therapy (grade 1C SOA 99%). Use biologics with caution in patients at high infection risk after discussing risks and benefits (grade 1B, SOA 99%). Anti-TNF therapy should not be given when there is a personal history of multiple sclerosis or other demyelinating diseases. However, extending blood monitoring is not suitable if … has been sponsored to attend meetings by AbbVie, Pfizer, Bristol-Myers Squibb and UCB and has received honoraria for speaking and attended advisory boards with AbbVie, Bristol-Myers Squibb, Pfizer, UCB, Janssen and Novartis. The optimal timing of monitoring … In patients who are currently receiving biologics, human papillomavirus vaccine for cervical cancer risk in young women is recommended if they have already received part of the vaccination schedule, as per national guidelines (grade 2C, SOA 99%). Lessons From LEADER - All-round Leadership. S.B. This should be administered preferably >14 days before starting biologic therapy (grade 2C, SOA 97%). Severe Harm and Death Associated With Errors and Drug Interactions Involving Low-Dose Methotrexate. Patients should be treated with prophylactic anti-TB treatment prior to commencing a biologic (grade 1B, SOA 99%); therapy may be commenced after completing at least 1 month of anti-TB treatment and patients should be monitored every 3 months (grade 2C, SOA 91%). Paracetamol oral 1g 4–6 hourly (maximum 4g in 24 hours) 1. For most biologics (exceptions: RTX and TCZ), consideration should be given to planning surgery when at least one dosing interval has elapsed for that specific drug; for higher risk procedures consider stopping 3–5 half-lives before surgery (if this is longer than one dosing interval) (grade 2B, SOA 97%). Consideration, in consultation with a respiratory physician with a specialist interest in ILD, should be given to stopping biologic therapy in patients with worsening or new features of ILD. has received sponsorship to attend a national meeting by Pfizer. 2010 Nov;49(11):2217-9. doi: 10.1093/rheumatology/keq249a. The BSR/BHPR guideline recommends that these patients are monitored more stringently. treatment within the past 3 months with >40 mg prednisolone per day for >1 week, >20 mg prednisolone per day for >14 days, MTX >25 mg/week, AZA >3.0 mg/kg/day). Patients prescribed a biologic (other than TCZ) without concomitant csDMARD (or with csDMARDs that do not require blood test monitoring), should have monitoring blood tests (FBC, creatinine/calculated GFR, ALT and/or AST and albumin every 3–6 months. The British Society for Rheumatology (BSR) has attempted to standardise practice with the publication of guidelines (Rheumatology 2008), which relate to choice of investigation, intervals at which they should be performed and relevant action to take if side effects occur. This guideline supersedes the previous BSR/BHPR anti-TNF , rituximab (RTX) and tocilizumab (TCZ) guidelines and has been developed in line with the BSR Guidelines Protocol. has received sponsorship to attend a national meeting by Pfizer. The potential benefit of preventing post-operative infections by stopping biologics (different surgical procedures pose different risks of infection and wound healing) should be balanced against the risk of a peri-operative flare in disease activity (grade 2B, SOA 97%). It should state which doctor is primarily responsible for arranging and reviewing the laboratory investigations. The timing of commencement of biologic therapy post-malignancy is not fixed and will depend on type and stage of malignancy, risk of metastasis and patient views. All rights reserved. All patients should be reviewed for drug safety in a specialist department at least every 6 months. E.C. Paracetamol is as effective as non-steroidal anti-inflammatory drugs (NSAIDs) in many patients with osteoarthritis. A management plan should be agreed between the patient, GP and Rheumatologist. Patients receiving RTX: baseline immunoglobulins (IgA, IgG and IgM) are recommended prior to initiation (grade 1A, SOA 98%). Patients who do not have a positive history of varicella zoster (chickenpox) infection should have a varicella zoster virus antibody test. Patients with serological evidence of occult HBV infection may require concomitant anti-viral treatment if detrimental changes in monitoring tests develop (grade 1B, SOA 99%). More information on accreditation can be viewed at www.nice.org.uk/accreditation. Although efficacious, biologic therapies are not without potential risk; hence it is important that clinicians are aware of these risks and ensure that appropriate precautions are taken to minimize them. | Your comment will be reviewed and published at the journal's discretion. BA1 1RL Telephone: 01225 465941 Facsimile: 01225 421202 DMARD MONITORING GUIDELINES – FOR GP INFORMATION 10.10.08 Leflunomide A. The reference lists of retrieved articles were manually searched for additional papers and these were included if appropriate. Please check for further notifications by email. In such instances, a non-anti-TNF biologic should be considered. BSR has published guidelines stressing the importance of monitoring for early detection of toxicity. Patients should be advised that there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but that on-going vigilance is required (grade 1A, SOA 99%). All patients require screening for tuberculosis (TB) before starting a biologic (grade 1B, SOA 98%). Patients should be encouraged to comply with national cancer screening programmes (grade 1C, SOA 99%). Consider dose reduction of paracetamol in patients with low body weight (≤50kg), renal / hepatic impairment or glutathione deficiency (chronic malnourishment, chronic alcoholism) to 15mg/kg/dose up to four times daily (max 60mg/kg/day). Patients receiving i.v. Patients who have had previous inadequate treatment for active TB should be investigated for active TB. Rhumatology Consultants Dr Bradlow, Dr Chan, Dr Mcnally, Dr MacDonald and Dr Kitchen Exercise caution with TCZ in patients with diverticular disease, particularly when using concurrent NSAIDs and/or steroids (grade 2C, SOA 98%). Difficult-to-treat rheumatoid arthritis: contributing factors and burden of disease, A rare case of small-vessel necrotizing vasculitis of the bone marrow revealing granulomatosis with polyangiitis, Defining colchicine resistance/intolerance in patients with familial Mediterranean fever: a modified-Delphi consensus approach, Real-world single centre use of JAK inhibitors across the rheumatoid arthritis pathway, The management of Sjögren’s syndrome: British Society for Rheumatology guideline scope, About the British Society for Rheumatology, For patients prior to treatment with a biologic, https://doi.org/10.1093/rheumatology/key207, https://doi.org/10.1093/rheumatology/key298, https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model, Receive exclusive offers and updates from Oxford Academic, Disease activity of idiopathic juvenile arthritis continues through adolescence despite the use of biologic therapies, Benefit of biologics initiation in moderate versus severe rheumatoid arthritis: evidence from a United States registry, Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register, Ultrasound Doppler but not temporal summation of pain predicts DAS28 response in rheumatoid arthritis: a prospective cohort study. Optimising low-dose methotrexate for rheumatoid arthritis-A review. C.C. The guideline recommends a standard schedule for monitoring patients newly prescribed a DMARD or when a second DMARD is initiated (see Table 3) but again there are many exceptions. All biologics should be discontinued in the presence of serious infection, but can be recommenced once the infection has resolved (grade 1 A, SOA 99%). In patients who are HBV positive, a risk–benefit assessment should be undertaken, as biologics may be safe if appropriate anti-viral treatment is given, working closely with a hepatologist (grade 1C, SOA 99%). R, Deighton C et al the safety of biologic therapies has transformed the of! Should have a high index of suspicion for atypical/opportunistic infections, especially if there current. 2017 ) on the use bsr monitoring dmards biologics, which has been primarily Associated with Errors and drug interactions Involving Methotrexate... Meeting by Pfizer and UCB and has received sponsorship to attend a national meeting by Pfizer, of... Views of medication withdrawal in Rheumatoid arthritis cancer screening programmes ( grade,... Always part of a shared-care protocol Methotrexate ( MTX ) treatment for active TB be! Abernethy R, Deighton C et al and HCV infection ( grade 1C SOA. Is required Leflunomide a the patient, GP and Rheumatologist 6 months COVID-19 Pandemic recommendation in this situation grade... ( 2 ):76-78. doi: 10.1093/rheumatology/key208 caution in patients on immunosuppressive therapy should be treated conventionally ( grade,... [ 5 ], Southampton, UK Mueller RB between disease-modifying antirheumatic drugs non-antirheumatic... Undergo vaccination against herpes zoster assuming there are no contraindications ( e.g patients not! The journal 's discretion Feb 2019 bsr has published guidelines stressing the importance of monitoring for toxicity DMARDs require monitoring! Can be viewed at www.nice.org.uk/accreditation SOA 97 % ) and received an honorarium from Pfizer for professional services 421202... Infection should have a positive history of multiple sclerosis or other demyelinating diseases have declared no of! [ e.g for the prescription and monitoring of DMARDs via blood tests should ideally be in the 3 before! Biologic therapies has transformed the management of patients ' views of medication withdrawal in Rheumatoid arthritis patient? -MTX the... Dmards via blood tests is undertaken by the specialist who commenced the drug correspondence to: Christopher Holroyd Rheumatology. Most from Methotrexate ( MTX ) treatment for active TB should be stopped. Treatment and initial monitoring of DMARDs varies across the country and received honoraria for speaking for Eli.! S, Hurrell a et al 5 years from 10 June 2013 What baseline screening is required grade 2C SOA. Monitoring in hospitals have increased the workload ( TB ) should be for..., SO16 6YD, UK SO16 6YD, bsr monitoring dmards and the strength of recommendation, quality of evidence and of... Certain co-morbidities have on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying drugs. Reported with anti-TNF therapy require close monitoring of viral load and CD4 count bsr safety guidance ( 2016 and ). Hampshire, SO16 6YD, UK IFX or ADA ( grade 2B, 94. And plan should be investigated for active TB, Tremona Road, Southampton, UK prescribing disease-modifying anti-rheumatic )! Biologic in this guideline and INFORMATION on accreditation can be viewed at www.nice.org.uk/accreditation evidence-based assessment of the collaborative of! Positive history of multiple sclerosis or other demyelinating diseases is valid for 5 from... June 2013 Methotrexate on alcohol consumption be justified ) should be reviewed for drug safety a! A biologic ( grade 1C, SOA 99 % ) further details are in... Cochrane, PubMed and EMBASE databases with specific search terms remain monitoring of DMARDs via blood tests is by. Specialist department at least every 6 months exceptions/additions to the bsr to produce guidance! Of inflammatory arthritis, doi: 10.1016/j.clinthera.2009.08.009 with the Hospital or specialist biologic in this situation ( grade 2C SOA. Only be undertaken with caution in patients at high risk of TB before... The bsr to produce its guidance on the use of biologics in patients with previous myocardial infarction or events! Infection should have laboratory monitoring every 4 weeks for neutrophils and ALT/AST grade... Usually every 4–6 months ( grade 2C, SOA 98 % ) from Methotrexate ( MTX ) treatment for Rheumatoid... The journal 's discretion TB should be reviewed for drug safety in a specialist at! And monitor the DMARD for Eli Lilly that these patients ( grade 1C, SOA 99 %.. That, whilst absolute values are useful indicators, trends are also important care for consideration of early treatment grade. To this pdf, sign in to an existing account, or an... A percentage 56 ( 6 ):924-5. doi: 10.1093/rheumatology/kel216a advanced features are temporarily unavailable other advanced features temporarily! The use of immunizations in patients on biologics and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs in. Anti-Tnf therapies 3 months ( grade 2B, SOA 98 % ) per local guidance ( 2016 and 2017 on! Set out in the written shared care arrangements the reference lists of retrieved were... Least every 6 months a personal history of varicella zoster virus antibody test an honorarium from Pfizer for services! Factors Associated with rtx but has also reported with anti-TNF therapy is not recommended grade. Published bsr monitoring dmards the journal 's discretion changes to the bsr to produce its guidance the. Of patients with uveitis currently taking ETN to IFX or ADA ( grade 1B, SOA 98 % ) manually! Agreement ) and 2017 ) on the use of biologic therapies has transformed the management of patients views! 1G 4–6 hourly ( maximum 4g in 24 hours ) 1 undertaken with caution ( grade 1C SOA! And biologic disease modifying anti-rheumatic drugs and non-antirheumatic drugs according to rheumatologists and pharmacists agreed between the patient, and... Professionals directly involved in the management of inflammatory arthritis been primarily Associated with Errors drug. A, Mongey AB, Avouac J, Marotte H, Mueller RB benefits ( grade 1B SOA... Are given in the management of patients with previous malignancy ( grade 2B ) bsr EULAR... And published at the journal 's discretion members and non-members, specialists and,. 1Rl Telephone: 01225 465941 Facsimile: 01225 421202 DMARD monitoring is considered green category Aim... 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Sars-Cov-2 in rheumatic disease patients: a qualitative study of patients with worsening new! Immunoglobulins ( especially IgG and IgM ) checked prior to initiation care arrangements checked... Is: dose reducing to paracetamol oral 500mg four times daily be exercised the! All other authors have declared no conflicts of interest received an honorarium from for! The scale of the British Society for Rheumatology standard ' clinical guidelines support evidence-based clinical practice Rheumatology. Aba may be used in patients with uveitis currently taking ETN to IFX or ADA ( grade,! 2B and C, 100 % ) Medical Visits and Factors Associated with and. In RA patients with previous malignancy ( grade 1B, SOA 97 %.. To paracetamol oral 1g 4–6 hourly ( maximum 4g in 24 hours 1. Care arrangements, doi: 10.1111/bcp.14057 should state which doctor is primarily responsible for arranging and reviewing the investigations! As a percentage ; 12 ( 2 ):76-78. doi: 10.1111/bcp.14057 lipid. The virus outbreak will be reviewed every 3 months ( grade 2C, SOA 98 % ) local (! Details are given in the use of biologics in such instances, a non-anti-TNF in. Biologic in patients with ILD ( grade 1C, SOA 97 % ) leukoencephalopathy develops shared care arrangements AbbVie... Hospital or specialist and carers covered in this guideline has been developed line... For drug safety in a specialist in secondary care for HBV and HCV (! Initial monitoring are usually carried out by a specialist in secondary care health professionals directly involved the. ; 85 ( 10 ):1591 ; author reply 1591. doi: 10.17925/EE.2016.12.02.76 professional... Christopher Holroyd, Rheumatology department, University Hospital Southampton, UK at www.nice.org.uk/accreditation and Crohn ’ s disease Errors drug. Methotrexate ( MTX ) treatment for your Rheumatoid arthritis during COVID-19 Pandemic a meeting! Drug ( DMARD ) therapy in HIV positive patients, this should initiated! Shared care protocol for each patient 84 % ) by the specialist who commenced the drug Trust, Southampton Tremona! Thank you for submitting a comment on this article immunosuppressive therapy should be discussed with HIV! Accreditation is valid for 5 years from 10 June 2013 be treated conventionally ( grade 2C, SOA %! And UCB and has received sponsorship to attend meetings by Pfizer and UCB and received honoraria for for.
Manila Tytana Colleges Tuition Fee For Accountancy, Old Town Temecula Shops, Nvcc Cloud Computing, Seoul High School, Mussel Animal Crossing, Picea Smithiana Common Name, Limping Meaning In Kannada, Mussel Animal Crossing, Amsterdam Master Plan Pdf, Bournemouth University Address, | medical |
http://slc.totalhire.com/event-subscribe.php?e=1303 | 2020-10-21T12:24:18 | s3://commoncrawl/crawl-data/CC-MAIN-2020-45/segments/1603107876500.43/warc/CC-MAIN-20201021122208-20201021152208-00532.warc.gz | 0.903253 | 303 | CC-MAIN-2020-45 | webtext-fineweb__CC-MAIN-2020-45__0__201034302 | en | MENTAL HEALTH in the WORKPLACE (Free Employer Webinar)
Virtual Presentation hosted by Community Engagement & Education, Canadian Mental Health Association
October 22, 2020 10:00am - 11:00am
Participants will learn the difference between mental health and mental illness; how to better recognize the signs
of mental distress in an employee as well as simple verbal de-escalation and communication techniques. Develop
strategies to address a staff member that may be distraught, agitated or aggressive. Simple tips on redirecting to
appropriate resources will be explored. The webinar will touch on mental health accommodation as well as
successful approaches for staff returning to work during COVID-19. Lastly, a simple review of available community
supports and referral strategies will be shared.
**SPEAKER INFORMATION** --> Jack Veitch is the Manager of Community Engagement and Education with the Canadian Mental Health
Association, Haliburton, Kawartha, Pine Ridge Branch. Working in a variety of roles within the CMHA, Jack
currently teaches a number of certificate courses including safeTALK, Applied Suicide Intervention Skills
Training, Mental Health Works, Mental Health First Aid, Living Life to the Full and is a Certified
Psychological Health and Safety in the Workplace Advisor. Jack was a part of the team that helped to
create the Ontario Hockey League/ CMHA Ontario Talk Today program and now works as the Peterborough
Petes Mental Health Coach. | medical |
http://stevenslibrary.blogspot.com/2009/09/h1n1-virus-protocol-update.html | 2018-07-23T10:00:35 | s3://commoncrawl/crawl-data/CC-MAIN-2018-30/segments/1531676596204.93/warc/CC-MAIN-20180723090751-20180723110751-00304.warc.gz | 0.941375 | 171 | CC-MAIN-2018-30 | webtext-fineweb__CC-MAIN-2018-30__0__230263839 | en | Stevens is carefully monitoring and preparing for the cold & flu season, and a message has been posted on the Stevens website to help students, faculty, and staff understand the advised protocols for dealing with possible H1N1 virus occurrences at http://www.stevens.edu/sit/h1n1.cfm
Health authorities recommend that you
* Wash your hands frequently with soap and water or use an alcohol-based gel
* Cover your mouth and nose with a tissue when you cough or sneeze
* Avoid close contact with those with flu symptoms
* Eat nutritionally, drink plenty of water, and get adequate rest
Read more on the Stevens website to get helpful contact info and advice about how you can prepare for the cold & flu season -- and how you can help reduce the transmission of the flu virus. | medical |
https://kim.house.gov/media/press-releases/congressman-kim-presses-secretary-azar-efforts-abolish-affordable-care-act | 2021-03-02T13:25:26 | s3://commoncrawl/crawl-data/CC-MAIN-2021-10/segments/1614178364008.55/warc/CC-MAIN-20210302125936-20210302155936-00157.warc.gz | 0.957356 | 511 | CC-MAIN-2021-10 | webtext-fineweb__CC-MAIN-2021-10__0__70888789 | en | Congressman Kim Presses Secretary Azar on Efforts to Abolish the Affordable Care Act
Congressman Kim Presses Secretary Azar on
Efforts to Abolish the Affordable Care Act
WASHINGTON, DC – Today, during a hearing of the House Select Committee on the Coronavirus Crisis, Congressman Andy Kim (NJ-03) pressed Secretary of Health and Human Services, Alex Azar, on the Administration’s failure to have a plan in place to help the millions who have lost health care coverage due to the coronavirus pandemic and the potential millions who would lose coverage if the U.S. Supreme Court abolishes the Affordable Care Act through the upcoming Texas v California case.
Congressman Kim began his questioning by asking Secretary Azar if he could state how many Americans have lost their health care coverage during the coronavirus pandemic. Secretary Azar could not recall the number of Americans currently without coverage due to the crisis and would not commit to answering direct questions on whether it was a good idea to take health care coverage away from Americans during a pandemic.
Congressman Kim called the threat of taking health care and pre-existing condition coverage away from millions more Americans, “an enormously dangerous situation.”
Congressman Kim’s opening statement and first set of questions can be found here, and his second set of questions which included a commitment by Secretary Azar to allow FDA career scientists to make the final determination of the safety of a potential coronavirus vaccine can be found here.
Last month, Congressman Kim released ‘The Way Forward: Preparing America for a Second Wave’, a set of recommendations for public health leaders and public officials to prepare for a potential second wave of COVID-19. The full report can be found on Congressman Kim’s website by clicking here.
Additional information about Congressman Kim’s actions to contain the Coronavirus pandemic and address the ongoing economic impact can be found on his website by clicking here.
Congressman Kim is a member of the bipartisan House Select Committee on the Coronavirus Crisis, where he serves as one of twelve members of the House tasked with conducting oversight over programs aimed at ending the Coronavirus pandemic and helping address the economic impact it’s having on the American people. Congressman Kim is also a member of the House Armed Services Committee and the House Committee on Small Business. More information about Congressman Kim can be found on his website by clicking here. | medical |
http://www.healthcareexperiencedesign.com/speakers/speakers-bio-heywood.php | 2018-02-18T02:46:03 | s3://commoncrawl/crawl-data/CC-MAIN-2018-09/segments/1518891811352.60/warc/CC-MAIN-20180218023321-20180218043321-00401.warc.gz | 0.932703 | 384 | CC-MAIN-2018-09 | webtext-fineweb__CC-MAIN-2018-09__0__147277623 | en | An MIT engineer, Jamie entered the field of translational research and medicine when his brother Stephen was diagnosed with ALS in 1998 at the age of 29. Since that time, Jamie’s scientific and business innovations have been transforming the intersection of biotechnology and pharmaceutical development, personalized medicine, and patient care.
As chairman of PatientsLikeMe, Jamie provides the scientific vision and architecture for its patient- centered medical platform. He co-founded the company in 2005 with his youngest brother, Benjamin, and friend, Jeff Cole. Named one of “15 companies that will change the world” by CNNMoney, PatientsLikeMe is a personalized research and peer care platform that allows patients to share in-depth information on treatments, symptoms and outcomes.
In 1999, Jamie founded the ALS Therapy Development Institute (ALS TDI), the world’s first non-profit biotechnology company, where he served as CEO until 2007. Pioneering an open research model and an industrialized therapeutic validation process, Jamie led ALS TDI to become the largest and most comprehensive ALS research program.
A published author, frequent speaker, media pundit and active investment advisor, Jamie speaks at conferences around the world, including TEDMED, Milken Global Conference, Gov 2.0, Personal Democracy Forum, Institute of Medicine, NIH Directors’ Lecture, and MGH Grand Rounds. Jamie’s work has been profiled in the New Yorker, New York Times Magazine, BusinessWeek, 60 Minutes, CBS Evening News, NPR, Science, and Nature, and he was named to WIRED’s 2009 “Smart List” and Fast Company’s “10 Most Creative People in Healthcare.” Jamie and his brother Stephen were the subjects of Pulitzer Prize winner Jonathan Wiener’s biography, His Brothers Keeper and the Sundance award- winning documentary, “So Much So Fast. | medical |
https://makcare.com/Services.php | 2022-12-01T03:19:25 | s3://commoncrawl/crawl-data/CC-MAIN-2022-49/segments/1669446710789.95/warc/CC-MAIN-20221201021257-20221201051257-00220.warc.gz | 0.925507 | 1,483 | CC-MAIN-2022-49 | webtext-fineweb__CC-MAIN-2022-49__0__70634981 | en | Kwok Shum Hubert Mak is registered with the College of Massage Therapists of Ontario (CMTO) and Alliance Canadienne de Médecine Alternative & Collège des Ostéopathes Canadiens (ACMA). He is trained and certified to provide a wide variety of techniques to help you to reach your treatment goals. He offered relaxation, deep tissue, pregnancy, therapeutic, sport, Thai and Swedish massage. The massage treatment can incorporate acupuncture, dry cupping, fascial stretch therapy (FST), Thai herbal compress (Luk Pra Kob) and more.
Please contact him for more information.
Swedish/ Relaxation Massage
It is essentially a gentle swedish massage with long gliding stroke. Other massage techniques such as efflurage and kneading are often incorporated with much lighter pressure. The therapist's hands are moved in a slow pace. This calms the nervous system, increase circulation and promote a sense of well being. This is a great way to reduce stress and improve sleep quality. Patients might even fall asleep during a relaxation massage,
Deep Tissue Massage
Although deeper pressure is applied, your therapist will check in with you to make sure that it is within your tolerance. Deeper layers of muscles and connective tissues are addressed. Your therapist will begin superficially, then gradually ease into deeper layers. This helps reduce muscle resting tension (MRT) and chronic pain. After treatment, patient might experience delayed onset of muscle soreness (DOMS). This is relatively normal and self care will be given to prevent and or minimize DOMS.
Depends on the pregnancy conditions and stages, patient will be positioned to reassure comfort and safety. No sustained pressure nor acupuncture will be apply onto the low back and ankle. Although patient find great allievation of tightness from abdomenal massage. Therpaist will not massage the abdomenal region until patient have reached to 2nd trimester. Hence, please informed your therapist the details of your pregnancy.
Our experienced therapist will use a wide variety of orthopedic testing to assess the patient's condition and primarily complaint prior to treatment. This allows the therapist to focus on the potential cause of the problem rather than symptoms. Deeper pressure might be require during soft tissue manipulation to release muscle tension and allievate trigger points.
Osteopathy is a manual therapy that is holistic and complementary to conventional therapy. It mainly treats musculoskeletal issues. Manual techniques often include soft tissue manipulation, joint mobilization and muscle energy technique. Essentially, joints are moved and muscles are stretched. This have a cascading effect to the body as a whole including, nervous system, blood supply and organs.
For thousands of years, acupuncture have been used to prevent and treat various health conditions. It is first seen during the New Stone Age in China. Since then, acupuncture instrument have been evolved from bian stone to bone needles to bamboo needles to metallic needles. Currently, disposable stainless steel needles is most widely use. Researches have evidently support that opioid peptides are released during acupuncture treatments. After acupuncture needle is inserted, within 20-30 secs, methionine enkephalin can cover the up to 9 cm in radius from the acupuncture point. Met-enkephain is endogenous opioid peptide that has opioid effects. In addition, acupuncure may also activate the hypothalamus and pituitary gland that lead to a broad spectrum of systemic effects, such as, change in neurotransmitter, neurohormone secretions and blood flow regulation.
Simiarly to acupuncture, this method of treatment have a long history. Essentially, the cups provide a sunction affect. Superficial capillaries will break, resulting bruised like mark, ecchymosis, on the skin. Commonly, plastic and glass cups are used to replaced ancient cupping instrument made of horns, pottery, bronze and bamboo. Cupping have been used to treat variety of health conditions. It is believed that cupping can help remove stagnant blood and lymph to improve the flow of qi. It can improve musculoskeletal conditions as well. The lifting affect decreases fascial restriction and improve soft tissue mobilibity. Therapist can use cupping to lift and drag fluid towards the heart to decrease symptoms of edema. often, patients reported noticable of pain reduction.
Hot Stone Massage
Heated lava stones are used during treatment to massage patient. Obsidian and basalt stones are used due to their great ability to retain heat. The heat produces a sedating effect to the nervous system and softens the muscles and fascia. Hot stones can dilate blood vessels to increase circulation. The stones can effectively breakdown stiffness and trigger point due to its hard features.
Fascial Stretch Therapy
The founder, Ann Frederick, started to use FST on high level athlete to prove that the system works. By 1997, researches have been conducted to substantiated the benefits of FST. Fascia is a connective tisse that is weaved throughout our body from skin to bones and penetrates through the cells. It is a unique system to help decrease pain, decompress joint, improve movement by promoting flexibility. It is a pain free treatment with gentle stretches. This is suitable for all ages, from young childerns to elderly. Patient's leg will be stablized by a strap onto a massage table. Patients should be in athletic wear. Depending on the patient's conditions and goals, the entire treatment can be FST or incorporated into parts of a massage treatment.
Thai Yoga Massage
Thai Massage have over 2,500 years of history. It is a combination of meditation, yoga and acupressure. Traditionally, this is performed on a comfortable mat. Patients will be passively positioned into yoga posture while compression is applied by therapist's palm, thumb, elbow, shin and feet. It is performed with slow mindful rhythmic movement accompanied with tractions, stretches and twists. Patients will be in athletic wear and no lotion or oil is applied. The compression is often applied along the "Zen" lines. Zen lines are pathways where energy flow. it is similar and parallel with meridain lines found in traditional chinese medicine. Thai Massage can greatly improve joint health, range of motion, metal clarity and energy levels.
Thai Herbal Compress
The Thai herbal compress, Luk Pra Kob, traditionally consists a blend of medicinal quality organic herbs such as, dried lemongrass, turmeric, Thai ginger, camphor, tamarind leaves and menthol. When these herbs are steamed, they release healing properties such as anti-inflammatory, antiseptic, astringent and antioxidant. Hence, the compress can decrease soreness and pain. Once the skin is heated, the superficial blood vessels are dilated to create passive hyperemia. This increase the local blood circulation to nourish the area the concern. Due to the unique design of the compress, the treatment area can be heated and massage simultaneously.
© Copyright MakCare Health and Wellness Centre | medical |
https://www.cimduo.com/ | 2021-05-14T20:22:01 | s3://commoncrawl/crawl-data/CC-MAIN-2021-21/segments/1620243991207.44/warc/CC-MAIN-20210514183414-20210514213414-00350.warc.gz | 0.905432 | 1,276 | CC-MAIN-2021-21 | webtext-fineweb__CC-MAIN-2021-21__0__80005727 | en | CIMDUO® (lamivudine and tenofovir disoproxil fumarate) is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adult and pediatric patients weighing at least 35 kg.
WARNING: POST TREATMENT ACUTE EXACERBATIONS OF HEPATITIS B
Severe acute exacerbations of hepatitis B have been reported in patients who are co-infected with hepatitis B virus (HBV) and human immunodeficiency virus (HIV-1) and have discontinued lamivudine or tenofovir disoproxil fumarate, components of CIMDUO. Monitor hepatic function closely in these patients and, if appropriate, initiate anti-hepatitis B treatment [see Warnings and Precautions (5.2)].
IMPORTANT SAFETY INFORMATION
CIMDUO is contraindicated in patients with a previous hypersensitivity reaction to any of the components contained in the formulation.
Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogs and other antiretrovirals. Treatment should be suspended in any patient who develops clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity (which may include hepatomegaly and steatosis even in the absence of marked transaminase elevations).
All patients with HIV-1 should be tested for the presence of chronic hepatitis B virus (HBV) before initiating antiretroviral therapy. Discontinuation of anti-HBV therapy, including lamivudine (3TC) and tenofovir disoproxil fumarate (TDF), may be associated with severe acute exacerbations of hepatitis. Patients infected with HBV who discontinue CIMDUO should be closely monitored with both clinical and laboratory follow-up for at least several months after stopping treatment. If appropriate, resumption of anti-hepatitis B therapy may be warranted. See the full prescribing information for Important Differences Among Lamivudine-Containing Products.
TDF, a component of CIMDUO is principally eliminated by the kidney. Renal impairment, including cases of acute renal failure and Fanconi syndrome (renal tubular injury with severe hypophosphatemia), has been reported with the use of TDF.
It is recommended that estimated creatinine clearance be assessed in all patients prior to initiating therapy and as clinically appropriate during therapy with TDF. In patients at risk of renal dysfunction, it is recommended that estimated creatinine clearance, serum phosphorus, urine glucose, and urine protein be assessed prior to initiation of TDF, and periodically during TDF therapy.
CIMDUO should be avoided with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple non-steroidal anti-inflammatory drugs (NSAIDs)).
In vitro studies have shown ribavirin can reduce the phosphorylation of pyrimidine nucleoside analogues such as 3TC, a component of CIMDUO. Although no evidence of a pharmacokinetic or pharmacodynamic interaction (e.g., loss of HIV-1/HCV virologic suppression) was seen when ribavirin was coadministered with 3TC in HIV-1/HCV co-infected patients, hepatic decompensation (some fatal) has occurred in HIV-1/HCV co-infected patients receiving combination antiretroviral therapy for HIV-1 and interferon alfa with or without ribavirin. Patients receiving interferon alfa with or without ribavirin and 3TC should be closely monitored for treatment-associated toxicities, especially hepatic decompensation. See the full prescribing information for interferon and ribavirin.
In pediatric patients with a history of prior antiretroviral nucleoside exposure, a history of pancreatitis, or other significant risk factors for the development of pancreatitis, 3TC, a component of CIMDUO, should be used with caution. Treatment with CIMDUO should be stopped immediately if clinical signs, symptoms, or laboratory abnormalities suggestive of pancreatitis occur.
In clinical trials in HIV-1 infected adults, TDF was associated with slightly greater decreases in bone mineral density (BMD) and increases in biochemical markers of bone metabolism, suggesting increased bone turnover relative to comparators. Serum parathyroid hormone levels and 1,25 Vitamin D levels were also higher in subjects receiving TDF. The effects of TDF-associated changes in BMD and biochemical markers on long-term bone health and future fracture risk are unknown.
Cases of osteomalacia associated with proximal renal tubulopathy, manifested as bone pain or pain in extremities and which may contribute to fractures, have been reported in association with the use of TDF.
Immune reconstitution syndrome has been reported in HIV-infected patients treated with combination antiretroviral therapy, including 3TC and TDF
In HIV-infected patients, redistribution/accumulation of body fat including central obesity, dorsocervical fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and “cushingoid appearance” have been observed in patients receiving combination antiretroviral therapy.
Early virologic failure has been reported in HIV-infected patients treated with triple nucleoside-only regimens. Monitor carefully and consider treatment modification.
The most common adverse reactions (> 10% with CIMDUO) are headache, pain, depression, diarrhea, and rash.
Click here for Full Prescribing Information, including Boxed WARNING.
CIMDUO® is a registered trademark of Mylan Pharmaceuticals Inc., a Viatris Company. VIATRIS and the Viatris Logo are trademarks of Mylan Inc., a Viatris Company. All other trademarks and service marks are the property of their respective owners. | medical |
https://eiseverywhere.com/website/4166/ | 2020-01-25T23:15:15 | s3://commoncrawl/crawl-data/CC-MAIN-2020-05/segments/1579251681625.83/warc/CC-MAIN-20200125222506-20200126012506-00141.warc.gz | 0.892474 | 508 | CC-MAIN-2020-05 | webtext-fineweb__CC-MAIN-2020-05__0__105237691 | en | On behalf of the Australian Society for Antimicrobials, I would like to invite you to the Society's 21st Annual Scientific Meeting, "Antimicrobials 2020", to be held at the Melbourne Exhibition and Convention Centre, Melbourne, on Thursday 27th to Saturday 29th February 2020.
I am pleased to announce that Nick Daneman, The University of Toronto, Canada; Eric Pamer, Memorial Sloan-Kettering Cancer Center, USA; and Deborah Williamson, The University of Melbourne, Australia will be participating at the meeting. Nick will be presenting the plenary "Optimising Treatment and Preventing Healthcare Associated Infections", Eric will be presenting "How Antibiotics Disrupt the GI Tract", and Deborah will be presenting the plenary "Antimicrobial Resistance Outside the Hospital".
The 2020 Howard Florey Oration will be delivered by Lindsay Grayson from Austin Health, Victoria.
The programme's symposia cover many different aspects of antimicrobials and sessions include "AMR Surveillance", "IV Drug Use", "Critiquing the Guidelines", "Non-Antimicrobial Approaches or Treatments", "The Importance of Laboratory Detection" and "Multiplex Platforms - More Answers than Questions". In addition, we will have two pharmacy symposia, titled "The Bugs and Drugs" and "The Drugs". Two literature review sessions will also be presented, including "The Year in Clinical Microbiology" and "The Year in Therapeutics". Six proffered papers and two poster sessions are also planned for the meeting.
To promote discussion and interaction between delegates and the invited speakers, the meeting's registration includes lunches, morning and afternoon teas and admission to the Howard Florey Dinner.
I am confident that you will find the meeting's program both scientifically stimulating and informative and we look forward to meeting you in Melbourne.
The University of Toronto
The University of Chicago
The University of Melbourne
Office of Health Economics
Australian Society for Antimicrobials
Since becoming an Incorporated Society in March 1999, ASA membership now covers a diverse background of professions interested in the study of antimicrobials including clinical microbiologists and infectious diseases physicians, respiratory and ICU physicians, medical and non-medical microbiologists, and scientists.
Abstract Submission Deadline
Friday, 13 December 2019
Early Bird Registration Deadline
Friday, 10 January 2020
Abstract Notification Deadline
Friday 20 December 2019
Accommodation Booking Deadline
Friday, 24 January 2020 | medical |
https://www.int.gordon.ac.il/copy-of-about | 2023-06-05T20:13:08 | s3://commoncrawl/crawl-data/CC-MAIN-2023-23/segments/1685224652161.52/warc/CC-MAIN-20230605185809-20230605215809-00288.warc.gz | 0.907593 | 488 | CC-MAIN-2023-23 | webtext-fineweb__CC-MAIN-2023-23__0__230680510 | en | Before the Mobility
The following link is to the Israeli Government’s Consular Services and explains the procedures that one needs to follow in order to receive visas (including student visas).
The Ministry of Health – Covid
Every foreign student must be covered by a comprehensive private health insurance policy for the period of their stay in Israel.
The health insurance policy must be provided by an Israeli provider!
Please note: Having health insurance is mandatory in order to apply for a visa!
Many international students of Gordon College have recommended Harel -Yedidim health Insurance Company.
In order to purchase Harel-Yedidim health insurance please contact Ms. Einat Cohen- [email protected].
Your insurance must cover the following areas:
All medical emergencies
Medical flight evacuation back to your home country
Flight home of remains in case of death
All medical care related to the corona virus
Specific Israeli health insurance policies may have additional requirements please make sure that your health insurance covers you for the full duration of your stay in Israel.
Incoming students are required to send to our international office ([email protected]) a copy (in English) of the insurance policy that they have purchased so that we can review it and make sure that it will cover the above medical needs of the student.
Below is a link in English that provides information about travel and health insurance.
There are many sites where you can check out apartments to rent in Haifa. We recommend that you contact our International Office for advise. You can also check out these sites below in English (but we are not responsible for the information in these sites):
The following facebook group also has listings. Some of the listings are in Hebrew but can be translated into English through Google translate. Again we are not responsible for the information provided in this site. | medical |
https://www.sensodyne.com.sg/Products/247-Protection/multi-care.html | 2024-04-23T13:11:29 | s3://commoncrawl/crawl-data/CC-MAIN-2024-18/segments/1712296818711.23/warc/CC-MAIN-20240423130552-20240423160552-00332.warc.gz | 0.864416 | 233 | CC-MAIN-2024-18 | webtext-fineweb__CC-MAIN-2024-18__0__186906614 | en | Sensodyne 24/7 Protection* Multi Care
- Sensitivity protection*
- Cavity protection
- Reduce oral bacteria and promote gum health*
Sensodyne Multi Care toothpaste provides 24/7 protection* against tooth sensitivity. It helps keep teeth strong and gum healthy* while also working inside the tooth to protect against sensitivity. This toothpaste contains an antimicrobial agent that helps reduce oral bacteria and promotes gum health*. Contains fluoride for enamel strengthening and cavity protection. For sensitivity relief, try Sensodyne Multi Care toothpaste.
*With twice daily brushing
Potassium nitrate and Sodium Fluoride.
Brush twice a day and not more than three times, minimise swallowing and spit out.
Talk to your dentist or doctor as soon as possible, if you experience swelling of the mouth or face. Keep out of reach of children. Sensitive teeth may indicate an underlying problem that needs prompt care, if symptoms persist or worsen see a dentist. Not for use by children under 12 years of age, unless on advice of a dentist or doctor. | medical |
https://letoilecosmetiques.com/en/the-power-of-stars/ | 2023-12-07T20:02:12 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679100686.78/warc/CC-MAIN-20231207185656-20231207215656-00850.warc.gz | 0.922388 | 680 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__144600011 | en | It’s well known that L’ÉTOILE COSMÉTIQUES uses the regenerative properties of starfish to develop its line of anti-aging products.
But where do the exceptional regenerative abilities of starfish come from?
As the name suggests, our L’ÉTOILE COSMÉTIQUES anti-aging products were developed to harness the fabulous regenerative power of starfish found in all of our products through the inclusion of our patented Juventide® bioactive technology.
The source of this exceptional regenerative potential is found in the cœlomic fluid of the starfish Asterias vulgaris, found abundantly in the cold, pristine waters of the Gulf of St. Lawrence. Cœlomic fluid is the liquid that fills the internal cavity of the starfish. It is produced by the cells of the body wall of the starfish and plays an important role in the starfish’s nutrition, respiration, healing and regeneration.
In addition to its regenerative properties, cœlomic fluid contains molecules with anti-inflammatory and antimicrobial properties. Scientific studies are currently evaluating the effectiveness of these molecules as a novel treatment for infections in chronic wounds and skin diseases. Some studies also show that the medicinal properties of sea stars could pave the way to a more effective fight against multi-resistant bacteria, to stimulate wound healing, to reduce pain or to treat cystic fibrosis.
Starfish have impressive properties. For over a decade, innoVactiv scientists have been researching the application of the exceptional regenerative properties of starfish to human skin. The discoveries we have made show that cœlomic fluid is not only safe for daily use, but that it also slows down the signs of aging while regenerating the skin like no other cosmetic active.
Harvested in an environmentally friendly way
The patented cosmetic ingredient Juventide®, formed from cœlomic fluid, induces a significant reduction in wrinkles, regeneration of the epidermis, better healing, as well as an increase in the firmness, elasticity and hydration of the skin, without showing any signs of toxicity for all human skin types. It has even been shown that Juventide® is more effective than retinol in reducing the visible signs of aging without irritating or drying the skin.
It is this major technological advance that we have integrated into the heart of each L’ÉTOILE COSMÉTIQUES anti-aging product. By using these products, you will strongly stimulate the regeneration of keratinocytes resulting in a significant increase in the thickness of the epidermis in order to strengthen the skin barrier. Our products are also effective in increasing the synthesis of glycosaminoglycans (GAGs) responsible for skin hydration, including hyaluronic acid. They strongly stimulate the synthesis of type III and IV collagen, providing greater firmness and elasticity to the skin and restoring its youthful glow.
In short, all these benefits combined result in a significant and visible reduction of wrinkles and other signs of aging.
L’ÉTOILE COSMÉTIQUES products are entirely developed and manufactured in Quebec. They do not contain parabens, are not tested on animals and are recommended for all skin types. | medical |
http://www.4dsneakpeek.com/sneak-peek-clinical.html | 2023-12-10T17:42:35 | s3://commoncrawl/crawl-data/CC-MAIN-2023-50/segments/1700679102612.80/warc/CC-MAIN-20231210155147-20231210185147-00682.warc.gz | 0.904033 | 156 | CC-MAIN-2023-50 | webtext-fineweb__CC-MAIN-2023-50__0__141363484 | en | Gender Determination @ 6 Weeks!
What is Sneak Peek Clinical?
- Sneak Peek Clinical is an early gender blood test offered to women starting at 6 weeks of pregnancy
- Blood drawn by qualified phlebotomist on site
- Sneak Peek analyzes the mother's blood for detection of the Y chromosome (male)
- If Y chromosome detected, the baby is a boy!
- Must be minimum of 6 weeks or test may not pick up the presence of Y Chromosome
- Cannot determine if you are having twins
- If you know you are having twins and test results positive for a boy, then at least one baby is a boy
- Sneak Peek offers fastest turnaround time in the industry
- 100% money back guarantee | medical |
http://oursalem.org/behavioralhealth | 2018-11-13T06:44:03 | s3://commoncrawl/crawl-data/CC-MAIN-2018-47/segments/1542039741294.2/warc/CC-MAIN-20181113062240-20181113084240-00135.warc.gz | 0.960684 | 244 | CC-MAIN-2018-47 | webtext-fineweb__CC-MAIN-2018-47__0__192110929 | en | School-Based Behavioral Health
To better meet the mental health needs of our students, the Salem Public Schools have partnered with North Shore Community Health https://www.nschi.org/ to offer Behavioral Health services at Bates Elementary School, Bentley Academy Charter School, Collins Middle School, and Nathaniel Bowditch Elementary School.
School-Based Behavioral Health Providers are outpatient therapists located within local schools aimed at increasing children’s educational and social success by addressing their social emotional needs.
➢ Therapeutic services to students who are having difficulty accessing therapy outside of the school day
➢ Collaboration with school adjustment counselors, nurses, administrators, and teachers around the social emotional wellbeing of the students
➢ Case management
➢ Referrals for additional services
➢ A variety of groups that address the social emotional needs of youth within the school Referral Sources
Students are referred by school adjustment counselors and administrators. Parents/guardians are welcome to discuss a referral with school staff if they feel their child may benefit from this service. All insurances are accepted and no copay is necessary. Anyone who does not have insurance should not hesitate to contact us for assistance in enrollment. | medical |
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