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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This finding is consistent with the elevated augmentation index previously detected in HGPS 5. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This observation was also confirmed in the two sub-analyses that evaluated the same outcomes in patients reporting ALT/AST increases versus those with no increase, and in patients with ALT/AST elevations ≥15 × ULN versus those with ALT/AST elevation <15 × ULN. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | For example, B. anthracis spores have been recorded as surviving for 71 years on dried silk threads (19). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Previous study results on age at menarche and methylation were conflicting. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although we know of no test of the efficacy of pre- vs. post-quit attempt activities in cannabis cessation, several studies on tobacco self-quitters have found that preparatory actions such as telling someone that one is trying to change (Cobb, Niaura, Donaldson, & Graham, 2014) (Hughes JR et al, 2014c), and post-cessation actions such as coping behaviors (Fiore et al, 2008) predict abstinence. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This hypothesis is further supported by the absence of MBD3, which is part of the core NuRD complex, even if its constitutive presence in NuRD corepressor complex has been questioned [51]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In vitro and in vivo studies analyzed the prebiotic effect and fermentation properties of raw and roasted almonds, as well as almond seed and almond skin [40,44,45,46,47]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Sensitivity and specificity data could not be obtained due to the lack of follow-up with formal vision examination in the at-risk children. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | No significant improvements in C-statistics for all fractures or hip fractures were seen when GRS63 was added to a base model already including BMD. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study adds to the several studies that have validated symptoms of cannabis withdrawal (Del Boca & Darkes, 2003), by adding an externally valid test of these symptoms. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | On the other hand, the number of subjects in some of our subgroups (non-white race, had CVD event, smokers) was limited, raising the possibly that we may not have identified some clinically meaningful subgroup differences as statistically significant. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is as if the acuity of word–object associations has been diminished (or as if the grain of representation has become coarser) so that words are easier to understand and link to objects at the generic than at the specific levels of representation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Inflammation-Related Tradeoffs with Childhood Growth Are Buffered by Body Fat and May Have Lifetime Metabolic Effects. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Among opioids, morphine has been the gold standard for control of postoperative and chronic pain (Anghelescu, Oakes, & Popenhagen, 2006; Chou, Clark, & Helfand, 2003; Collins & Weisman, 2003; Quigley, 2005; Vascello & McQuillan, 2006; Zernikow et al., 2006). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The biomarkers investigated in this study reflect the immunological diversity that spans these patterns. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Second, increasing tubular pH decreases the generation of free radicals that are responsible for CIN 30,31. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In general, amniotic fluid analysis and histologic examination of the placenta are important methods of diagnosing intrauterine inflammation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There have been several more recent reports in which the AD GWAS loci have been evaluated more comprehensively and either eight [Vivot et al 2015] or nine [Carrasquillo et al 2015] AD-associated loci were tested for association with cognitive decline, including ABCA7, CD33, CLU, CR1, and MS4A4E that were nominally associated with cognitive phenotypes in the ARIC study. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The large effect of elevated CRP on child short-term growth is consistent with research involving in vitro models and chronic inflammatory diseases indicating that CRP and upstream proinflammatory cytokines inhibit bone growth via multiple direct and indirect pathways (citation). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While patient navigation may be sufficient to change short-term behaviors such as participation in screening, it may not be sufficiently intensive to promote longer-term behavior change as is necessary with smoking cessation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | One limitation of this study was missing data on some of the demographic information and some of the assessments. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The strict exclusion criteria may have limited any generalizability of the results to other patient groups. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Accessing the national collection of E. coli ST410 from Denmark, a cutoff value of no more than 40 SNP differences to the nearest neighbor seemed to define clones within this collection, as the closest genome differed by 159 to 185 SNPs to PC40-1 to -4 (see Fig. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We believe that the finding of limited documentation of pain intensity is a reflection of both the historical under-appreciation of pain in children in the 1980’s and 1990’s, and the lack of a structured institutional pain service until 2000 to lead the implementation of cultural changes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Grade 3/4 increases of ALT were reported in about 40% of patients after the first two cycles of chemotherapy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Indeed, there are a large number of patients (14/56) with chronic kidney disease presented abnormal shaped in adrenal gland, which was defined as full shape not hyperplasia. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, the present study demonstrate the good persistence of protection against HBV in a large sample of HCSs exposed to occupational health risk during the training programs, more than 20 y following the primary immunization courses. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Furthermore, we expected cognitive re-appraisal to be a mediating factor in the relation between prayer and pain tolerance. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Lower commuting distances and the availability of walking and cycling infrastructure were also associated with active commuting, which aligns with previous research. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This in turn may lead to a more accurate assessment of creatinine production, which is determined by the rate of muscle catabolism, thereby improving estimation of creatinine clearance and aminoglycoside CL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Finally, our study did not measure other cardio-metabolic biomarkers such as blood glucose, insulin, lipids, triglycerides and C-peptide, and thus lacking outcomes such as dysglycemia or dyslipidemia. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the performance characteristics of the microscopic detection method are very poor and cannot help in the diagnosis of MFI. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The age-profile of EV-D68 hospitalised cases is potentially due to young children and older adults being most at risk of severe acute respiratory infections. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | N-acetylcysteine has been evaluated in different meta-analyses that lead to incongruent results. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results raise the possibility that built environment attributes found to facilitate active commuting in higher-income countries do not fully generalize to LMICs. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | One of the most rooted dogmas in gastrointestinal surgery is the idea that an oral diet after resection should be introduced gradually, meaning nothing by mouth during the first few days after surgery, liquid meals in subsequent days, and full hospital diet within 4–5 postoperative days. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Approximately 20% of our group R patients received propofol for maintenance of anesthesia, which might explain the lower incidence of PONV in this group. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This may not altogether have eliminated the risk of measurement/registration errors, but has reduced the error size considerably. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both the GRS63 and the GRS16 predict fracture risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Lean or adjusted body weights have been demonstrated to best predict the volume of aminoglycosides in obese patients, yet they explained only around 1 to 4% of the observed variability in any measure of volume in this study (4, 5, 9). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Is intensified anticoagulation with intermediate or full therapeutic dosages required to protect hospitalized patients from VTE? |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Furthermore, a careful separation of the bladder and ureter from the cervix was recommended to minimize morbidity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In conclusion, we found that in our setting an intervention with home BP telemonitoring and pharmacist management improved BP control and lowered BP overall, but was particularly effective in younger patients, those without diabetes, those with elevated diastolic BP, and patients treated with fewer than three medication classes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, in cases of minor surgery such as thyroidectomy, continuous infusion of remifentanil can be inconvenient and expensive. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | First, correlational analyses showed that prayer is indeed positively related to pain but only to pain tolerance, and not to pain severity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A higher PaO2/FiO2 ratio could be observed at the PEEP level of 8 cm H2O, which should be associated with more well-distributed ventilation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, even with the total of 28 biopsies (13 from HLA-DQ2/8-positive and 15 from HLA-DQ2/8-negative patients), the effect sizes in SB inflammatory cells that could be detected between the two groups with 80% power (at α = 0.05) were 48% for CD3 lymphocytes, 50% for CD8 lymphocytes, and 31% for mast cells. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, all BMIz trajectories in the first 2 years were significantly associated with obesity at 5 years (a negative association for stable low BMIz trajectory and positive associations for stable high BMIz and rapid BMIz gain trajectories), while BMIz ≥95th percentile at 2 years was the only static measure with a significant association. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings show that Turkey has not reached the targeted aims of the breast cancer screening programs. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | They found tidal impedance increased only in the nondependent parts in the patients without lung disorders after decreasing the PEEP from 15 to 10 cm H2O. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In conclusion, this study has shown that the GRS63 predicts BMD, but not BMD change, in older Caucasian participants, suggesting that the genetic determinants of the acquisition of BMD differ from those of BMD change. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | LC is an increasing cause of morbidity and mortality, responsible for more than one million deaths every year4,19. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, experimental studies of the survival of C. burnetii spore-like forms have not demonstrated survival beyond 8 years (Table 6) (5,6). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Early-life energetic experiences have lasting impacts on phenotype (47–49). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This result is also consistent with the JACC study25, where long duration of sleep was associated with total stroke and ischemic stroke in a large cohort of Japanese men and women, our study extended the association to hemorrhagic stroke also. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In some patients with COVID-19, a prolonged APTT, which is frequently considered indicative of a systemic “coagulopathy,” may actually be caused by a lupus anticoagulant, 33 thus conferring an increased thrombotic rather than an increased hemorrhagic risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The above conclusion is consistent with the ProTECT III Trial's conclusion regarding its primary outcome measure, the GOSE, in demonstrating no compelling evidence for a neuroprotective effect of progesterone at 6 months after injury. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The surveillance data here provide evidence of current EV-D68 circulation in Wales. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, patients operated using the PA had less self-reported limping at 12 months. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Thus, the exact mechanism by which they shift the relative abundance of microbial communities and modulate fluctuations in the microflora composition in the gut in favor of butyrate-producing microbes is unknown. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The Mayo Clinic experience with contemporary cementing techniques using the Harris Design II component (HD-II, Howmedica, Rutherford, New Jersey) showed a rate of 1.6% of definite or probably loose stems at 5 to 7 years [25]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is comparable to the rates in other reports; however, the leakage rate was relatively high and may be the result of the small number of patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The notable finding of the current study was a considerable decrease in the development of PPCs. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We framed our study in the transactional theory of stress and coping (Lazarus & Folkman, 1984) and we tested the mediational role of re-appraisal in the association between prayer and pain. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the original GEFOS GWAS meta-analysis on BMD, the predictive value of the GRS16, but not the GRS63 was evaluated for fracture risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Given the complexity of care-seeking behaviour, we hope to gain a clearer understanding of the decision-making process, and the differential effects of poverty at different ages, through an ongoing qualitative study of this population. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Taking this into account, we can speculate that MCP-1 −2518 A/G SNP may be related to a particular phenotype of SSc. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the relationship between education and general QoL was not documented in previous studies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Overall, we identified five OTUs that were significantly associated with walnut consumption. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Continuous administration of remifentanil during major operations has distinct advantages, such as maintenance of stable vital signs, applicability to patients with kidney and liver conditions, and reduced respiratory depression30. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While speculative, immune-related energy constraint may have played a similar role in the evolution of extended subadulthood and a unique childhood life stage in the genus Homo (11), particularly given lifestyle changes (e.g., home-base foraging, enhanced sociality, increased physical activity) expected to elevate pathogen exposure in parallel with the evolution of increased brain size, body fat, and metabolic rate (17, 73–75). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our results show that the allele frequencies for both SLC4A1Δ27 and GYPCΔex3 polymorphisms differed in two ethnically and geographically distinct populations. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Hemostatic parameters should be monitored in all hospitalized patients with SARS-CoV-2 infection. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings are supported by the findings of an exploratory analysis of the safety and efficacy outcomes in pooled data from phase II trials of single-agent trabectedin in heavily and non-heavily pretreated patients with recurrent ovarian cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Such a response would be adaptive during childhood but could lead to obesity and poor metabolic health later in life should energetic conditions change (e.g., in association with economic development). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The rest of four HBV-related LC risk-related SNPs (rs9267673, rs264707, rs3997872 and rs9275319) were all located in molecules that belong to the HLA class II, which has been considered to be the most important host factors with respect to outcomes of HBV and HCV infections. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Recently, one prospective, randomized trial revealed that a better microbiological response was observed in patients treated with the regimen including streptomycin (20). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The lack of a relationship between cell-mediated immune function (i.e., EBV-Ab levels) and growth in the present study may similarly reflect poor correspondence of time courses. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although Georgia has achieved considerable success in controlling HIV/AIDS through prevention and treatment programs, social problems related to QoL, including stigma and discrimination, still remain challenges in PLWHIV. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is crucial to confirm whether beliefs about medicines are associated with self-medication as these findings can provide guidelines in public education to improve the safety aspects of self-medication. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | ECPs had healthier dietary patterns and ate main meals more regularly than NECPs in our study. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Kolb and Cioe subsequently confirmed these observations in Long Evans rat for parietal cortical areas closely corresponding to our sample area (Kolb & Cioe, 2001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this way we reproduced in small scale what happened in renal tubules of CRS Type 5 patients when systemic disorders induced cardiac and renal dysfunctions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study has several limitations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Alternatively, this finding may result from the observation that EBV-Ab levels, similar to those of CRP (37), can be impacted by stimuli other than antigen exposure (38). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A study conducted in Turkey showed that patient gained most of their information from health care professionals (Yılmaz et al, 2013). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Kutschera et al. [19] and Huo et al. [16] have reported no loosening at 5 years and at 3 to 6 years respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Despite increased government investment in public-sector healthcare, serial community surveys have shown falling perception of quality and satisfaction, with highest dissatisfaction among the poorest households [28]. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Truck drivers are a highly-mobile, pressured and hard-to-reach group, and traditional health promotion strategies may be limited in their effectiveness 3. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings reinforce the idea that BIM plays a major role in the surveillance against tumorigenesis in NPM/ALK-positive lymphomas and possibly in several lymphoid malignancies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The extrapolation of the results should consider these particularities. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Third, in agreement with our previous study 5, we found that a significant fraction of patients had systolic and diastolic BP above the 95th percentile. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | If straw board had been contaminated at some time in the past with a concentrated source of C. burnetii, drilling into this could have produced a cloud of dust containing large numbers of C. burnetii sporelike forms. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Sensory integration deficits included abnormal use of vestibular and somatosensory information for postural control as well as inadequate visual preference (Table 2). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | 71) by fostering extended periods of development and delayed maturation under energetically challenging conditions (27, 72). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The observation that the prevention of relapse or recurrence is often neglected may be attributable to the fact that many patients are reluctant to take (or physicians are reluctant to prescribe) long-term prophylactic treatment with antidepressant drugs with sometimes burdensome side effects after the acute symptoms of depression have disappeared (Keller and Boland, 1998; Montgomery and Kasper, 1998). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Second, like previous 1.5T MR cardiac vein imaging studies [6–10], we did not compare our 3.0T whole-heart CMRA technique with the current invasive gold standard, retrograde cardiac venography. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since the 1980s, other screw rings have been available with creation of the same gritblasted surface like that on the Alloclassic-CSF cup. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since anecdotally NP is often persistent and is reported by our patients to interfere with sleep and rehabilitation after LSS, the pain management service evaluated the prevention and treatment of NP. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In unadjusted models with NEWS-India aggregate scores, the active commuting model was significant, while the public transit model was not. |