dedup-isc-ft-v107-score
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0.420705 |
895ef268214c4baea32d790d1d2e73b3
|
Students’ satisfaction on face-to-face anatomy laboratory sessions.Students’ (n = 105) satisfaction on face-to-face anatomy laboratory sessions was ranked on a 3-point Likert-type scale (1 = satisfied and 3 = not satisfied). Students were asked about the impact of the modified schedules and methods of teaching in anatomy laboratory sessions they experienced after the COVID-19 pandemic, as represented by pie graphs. The 3- and 5-point Likert scale scores are shown in percentage. Abbreviation: COVID-19 = coronavirus disease 2019.
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PMC9000102
|
pone.0266426.g003.jpg
|
0.483523 |
153c18c5c89b409e9b56c4c51782e032
|
Schematic illustration of emission modes, detection mechanisms, and the applications of MOF-based fluorescent sensors for hazardous materials detection.
|
PMC9000234
|
molecules-27-02226-g001.jpg
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0.447308 |
88f0e0dc37c44121a4747a8c11dca69c
|
Emission modes of LMOFs.
|
PMC9000234
|
molecules-27-02226-g002.jpg
|
0.386059 |
dc3050674d7040148e6e6d29b515419b
|
Detection mechanisms of LMOFs.
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PMC9000234
|
molecules-27-02226-g003.jpg
|
0.396526 |
d2c9a60b6953419384b754a352abd5b1
|
(a) The post-synthesis process of UIO-66-ONa. (b) Fluorescence spectra of UIO-66-ONa after the gradual bubbling of CO2. (c) Fluorescence spectra of UIO-66-OH and UIO-66-ONa before and after bubbling of CO2. Adapted from [28].
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PMC9000234
|
molecules-27-02226-g004.jpg
|
0.432285 |
59ebb43e137b416f91f252413ffd145c
|
(a) The post-synthesis process of UiO-66-MA. (b) Fluorescence titration of UiO-66-MA with H2S (0-0.625 μM); inset: images of UiO-66-MA under day light (up) and UV light (down, 365 nm) in the presence of 0, 0.04, 0.08, 0.125, 0.165, 0.25, 0.35, and 0.625 μM of H2S for 1–8, respectively. (c) Fluorescence titration of UiO-66-MA/H2S with growing concentration of Cu2+; inset: images of UiO-66-MA/H2S under day light (up) and UV light (365 nm, down) in the presence of 0, 0.02, 0.07, 0.12, 0.17, 0.22, and 0.35 μM of Cu2+ for 0–6, respectively. (d) A possible tandem process in view of the Michael addition, and S-Cu integration was calculated by DFT. Adapted from [48].
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PMC9000234
|
molecules-27-02226-g005.jpg
|
0.407706 |
7e93e553317f4436a2f06903d647238c
|
(a) Diagram of the Ce4+/Tb3+ based Ln-MOF for sensing SO2 and sulfite via the turn-on of luminescence induced by energy transfer (ET) triggered by redox-reaction. (b) The luminescence of Ln-MOF increases with the concentration (0, 0.05, 0.1, 0.2, 0.5, 0.8, 1, 5, 20, 50, 100, 150, 200, and 300 mM) of SO32−; the inset shows the linear relationship of the luminescence intensity of Ce-PA-Tb at 545 nm with the concentration of SO32−. Adapted from [53].
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PMC9000234
|
molecules-27-02226-g006.jpg
|
0.441475 |
e356510dc30c4581ab71d07511b81179
|
(a) The structure of [Zr6O4(OH)4(FA)6]2(cal)3. (b) The luminescence intensity changes of [Zr6O4(OH)4(FA)6]2(cal)3 before and after bubbling of NO2. Adapted from [60].
|
PMC9000234
|
molecules-27-02226-g007.jpg
|
0.440646 |
0479bca49bfe4c20bb61ad6953d48b25
|
(a) The structure of 3D (Zn2(bpdc)2(bpee) and the schematic representation of the 2D structure potentially obtained after the NH3 detection. (b) The luminescence intensity changes of (Zn2(bpdc)2(bpee) immersed in aqueous solutions of NH3 with different concentrations. Adapted from [68].
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PMC9000234
|
molecules-27-02226-g008.jpg
|
0.449024 |
53c1a2919d4345a9b9fb01f3e3c18d98
|
Diagram of adsorption of [Pb(OH2)6]2+ on SO3H-UiO-66(Zr) in water. Adapted from [74].
|
PMC9000234
|
molecules-27-02226-g009.jpg
|
0.459385 |
07ebc6f41fd84502a69eb197ce264193
|
(a) Synthesis process of BA-Eu-MOF. (b) Schematic diagram of the sensing process of BA-Eu-MOF toward Hg2+ and CH3Hg+ ions based on transmetalation. Adapted from [82].
|
PMC9000234
|
molecules-27-02226-g010.jpg
|
0.403735 |
28d86b9bb666465e9c7f4a8e22a4d0a2
|
Structure of [Zn2(tdca)2(bppd)2]·2DMF, UV-vis spectra of [Zn2(tdca)2(bppd)2]·2DMF in acetonitrile suspension upon addition of Cd2+ at room temperature (λex = 330 nm), and photographs of the iodine release process in acetonitrile and hexane. Adapted from [86].
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PMC9000234
|
molecules-27-02226-g011.jpg
|
0.52516 |
0a21ec1b463c4a97b28f9a2c4d10df67
|
(a) Structure of L and Cd-MOF. (b) Fluorescence response of Cd-MOF to different metal ions. Adapted from [94].
|
PMC9000234
|
molecules-27-02226-g012.jpg
|
0.43235 |
e6d1ddc9ce4b4379b360a67f47b7938f
|
(a) Synthetic route of the post-synthesis modified PSM-4. (b) Fluorescence spectra of PSM-4 for the detection of Th4+. (c) Fluorescence spectra of PSM-4 for the detection of UO22+. (d) Fluorescence intensity of PSM-4 with the addition of different anions. Adapted from [96].
|
PMC9000234
|
molecules-27-02226-g013.jpg
|
0.404172 |
f866beba382a4a94ab9d617ccf4eafcf
|
(a) Structure of TJNU-302. (b) UV photos of TJNU-302 crystals before and after immersion in KReO4 water solution and emission spectra of TJNU-302 in water solutions containing different anions. Adapted from [100].
|
PMC9000234
|
molecules-27-02226-g014.jpg
|
0.432466 |
810a40de286c44c4a747e43ab71fa558
|
Quenching efficiencies of the tested antibiotics at different concentrations on the fluorescence of In(III)-MOF at room temperature; inset: the structure of In(III)-MOF. Adapted from [114].
|
PMC9000234
|
molecules-27-02226-g015.jpg
|
0.363742 |
433780f92f3745708cc1b0e35a21d1d7
|
(a) Representation of the sensing process of Mn/Fe-MIL(53) MOF nanoenzyme for OPs detection. UV–vis spectrum of nanoenzyme-TMB catalyzed system corresponding to different dosages of methyl parathion (b) and clorpyrifos (c). Adapted from [121].
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PMC9000234
|
molecules-27-02226-g016.jpg
|
0.43601 |
ed44ed71913048398c68a798ffa717c7
|
(a) Structure diagram of the as-prepared EY@DUT-52 sample. (b) Optical pictures of DUT-52 and three EY@DUT-52 samples under sunlight (the solvent in the vial is ethanol). (c) Fluorescent emission spectra of E@D1/ethanol suspensions with different concentrations of nitenpyram. (d) Fluorescent emission spectra of E@D3/ethanol suspensions with different concentrations of nitenpyram. Adapted from [127].
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PMC9000234
|
molecules-27-02226-g017.jpg
|
0.455589 |
99e4d5766bca445a8f542b8c378c81e8
|
Quenching efficiencies of tested nitro-explosives at different concentrations on the fluorescence of [Cd(NDC)0.5(PCA)]-Gx at room temperature; inset: the structure of [Cd(NDC)0.5(PCA)]-Gx. Adapted from [133].
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PMC9000234
|
molecules-27-02226-g018.jpg
|
0.421147 |
bb717c2d16d34d21a37b0a226fe9cee1
|
(a) Structure of [Mn6(L1)2(H2O)5]n. (b) Photographs of different solvent-loaded [Mn6(L1)2(H2O)5]n. (c) Perspective view of the hydrogen-bonding interaction between the acetophenone molecule (blue color) and host framework. Adapted from [139].
|
PMC9000234
|
molecules-27-02226-g019.jpg
|
0.395896 |
f09a6f63d64745ac8be6aef738735c78
|
(a) Schematic representation of the synthesis of Zr-BTDB-fcu-MOF (1). (b) PL spectra for (1) (red) and linker (black). (c) Fluorescence intensity of (1) aqueous suspension upon addition of 3 μM of of MA (c), aniline (d) (λmax = 515 nm). (e) Molecular structures of H2BTDB, H2BTDB with two and four MA molecules. Red arrows represent the dihedral angles between benzene and thiadiazole-based units, and red dashed lines indicate the hydrogen-bond lengths (dH) formed by H of MA and N of thiadiazole Adapted from [146].
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PMC9000234
|
molecules-27-02226-g020.jpg
|
0.473004 |
3a5e048f427d484bb162733f548e0047
|
PRISMA flow diagram representing the results of the search strategy
|
PMC9001209
|
590_2021_3019_Fig1_HTML.jpg
|
0.454392 |
c743edf8d87344a7abdb835929dfa9dc
|
Adopted synthetic route together with the amounts used for each reagent
|
PMC9001578
|
11356_2021_15515_Fig1_HTML.jpg
|
0.443479 |
eaab7bad25e74311ab96afbeca91f276
|
Exposure site at Monza Cathedral together with a schematic representation of the exposed samples
|
PMC9001578
|
11356_2021_15515_Fig2_HTML.jpg
|
0.411815 |
6ae3e233672f48c5913b4bd6bc857ba0
|
1H-NMR (proton nuclear magnetic resonance) spectra of all the synthesized MMA_F7 polymers. * = unidentified peaks
|
PMC9001578
|
11356_2021_15515_Fig3_HTML.jpg
|
0.400081 |
c6cee898969f44f4bc1541e49da7ad25
|
Topographic profile of a untreated C and b MMA_F7(1.0)@C. The roughness value (<R>) is reported as average value with the relative standard deviation. The coating thickness (highlighted by red arrow in b) was evaluated by scratching the film with a metallic pin. Scanning electron microscopy (SEM) images of c untreated marble, MMA_F7(1.0)@C, d before and e after the outdoor exposure together with the corresponding energy-dispersive X-ray spectroscopy (EDX) spectra
|
PMC9001578
|
11356_2021_15515_Fig4_HTML.jpg
|
0.406675 |
be8bda5ac0d24f828eeeeb00e2660f92
|
a Water absorption by capillarity and b water vapor transpirability by both untreated and MMA_F7(1.0)-treated Candoglia marbles, before and after outdoor exposure
|
PMC9001578
|
11356_2021_15515_Fig5_HTML.jpg
|
0.401327 |
bc5a1ea7b48e457ea2ed911ba37a0cfb
|
(Top) SEM images of PCL membranes obtained from electrospinning (A) 7.1, (B) 10.2 and (C) 11.7 wt% solutions. (D) Pore size distribution for the PCL membranes as determined by capillary flow porometer. (E) Distribution of fiber diameters for 7.1 (---), 10.2 (—) and 11.7 (···) wt% PCL membranes. (F) Relationship of fiber diameter and pore size to concentration of polymer solution in electrospinning of PCL.
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PMC9001631
|
41598_2022_10042_Fig1_HTML.jpg
|
0.502902 |
e582b1d697d94807a0396264df1b4381
|
Time course diffusion of bull sperm cells using solution electrospun PCL membranes with different thickness (A) 20 µm (B) 40 µm and (C) 60 µm and (D) 80 µm. (E) is the graph that illustrates the relationship between calculated time required to achieve maximum diffusion (processing time) in dependence to membrane thickness (with a high R2 of 0.983 from the linear regression of experimental data).
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PMC9001631
|
41598_2022_10042_Fig2_HTML.jpg
|
0.432545 |
d711cd4035be488dbb176d9073262d9f
|
Motile sperm cell population isolated from unfiltered and solution electrospun PCL membranes with different thickness (N = 6). Asterisk above show groups with no significant differences in means as evaluated using one way ANOVA and Tukey’s multiple comparison test.
|
PMC9001631
|
41598_2022_10042_Fig3_HTML.jpg
|
0.423042 |
13d1d00cf99445a6b4178df43822d8e6
|
Designed 3D printed modules and their intended vessels. The 3D printed module for the discontinuous assay is utilized in a microcentrifuge tube, while cuvette is used for the continuous assay. Process diagrams are show per respective assays.
|
PMC9001631
|
41598_2022_10042_Fig4_HTML.jpg
|
0.396744 |
39e5ab792a2f4018ae86fe7e00b6bc1b
|
Characterization of sorghum transformation.a–c Gene delivery capacity of ternary transformation system. Gene delivery was represented by the number of transgenic cells exhibiting YFP fluorescence on the surface of sorghum embryos. d–f Tissue culture response represented by callus proliferation after two weeks of Agrobacterium infection on the multi-purpose medium without selection. g–i YFP images of early-stage somatic embryo formation (indicated by the arrows) induced by morphogenic gene expression on the surface of immature scutella. j–l Shoot regeneration after four-week of maturation. m–o The pleiotropic impacts of morphogenic gene expression on single-copy QEs. a, d, g, j and m Tx430. b, e, h, k, and n Tx623. c, f, i, l and o Tx2752.
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PMC9001672
|
42003_2022_3308_Fig1_HTML.jpg
|
0.410535 |
98750f795d34468582d687202ac2b7a1
|
Somatic embryo formation and regeneration mediated by morphogenic gene excision-induced selection-activation system.Bright field and fluorescence images of early-stage somatic embryo formation (couple of examples indicated by the arrows) on the surface of immature scutella in Tx430 (a, b), Macia (c, d), Malisor 84-7 (e, f), Tegemeo (g, h). a, c, e, and g Bright field images. b, d, f, and h Fluorescence images. i Tx430 shoot regeneration after four-week maturation.
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PMC9001672
|
42003_2022_3308_Fig2_HTML.jpg
|
0.424919 |
1b2ab84819db439e84f60cae97de0c36
|
Somatic embryo formation and regeneration mediated by altruistic transformation system.Bright field images of early-stage somatic embryo formation (couple of examples indicated by the arrows) on the surface of immature scutella induced by altruistic transformation in Tx430 (a) and Macia (b). c Macia shoot regeneration after four-week maturation following by one week in dim light.
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PMC9001672
|
42003_2022_3308_Fig3_HTML.jpg
|
0.426177 |
f58a4349262a49f98812dde389b89381
|
Gene expression profiling of primary uveal melanomas (UMs) based on metastatic status.A Volcano plots showing differentially expression genes between metastatic tumors and non-metastatic tumors in TCGA UM cohort. B Heatmap showing the 89 most highly downregulated genes located on chromosome 3. Blue: decreased gene expression, red: increased gene expression. C Molecular landscape in 80 primary UMs of TCGA cohort. Mutation or expression status for six genes, the metastatic status of tumor sample, and chromosome 3 copy number alterations are indicated. D SLC25A38 was highly expressed in tumors with disomy 3 in TCGA UM cohort.
|
PMC9001737
|
41419_2022_4718_Fig1_HTML.jpg
|
0.481942 |
204e1d3deaf743fe96b9b71db00946c2
|
Model accuracy and survival analyses in UM.A–F Receiver Operator Curves based on different feature sets in TCGA cohort (A–C) and GSE22138 cohort (D–F). The predictive accuracy of SLC25A38 expression for risk of metastasis was superior to that of other biomarkers. The P-value in light blue in B indicates Binary SLC25A38 vs BAP1 Mut, and the P-value in dark blue in B indicates Binary SLC25A38 vs SF3B1 Mut. The P-value in light blue in C indicates Binary SLC25A38 vs Binary BAP1, and the P-value in dark blue in C indicates Binary SLC25A38 vs GEP Class. G–I Survival curves based on SLC25A38 expression level. Low expression of SLC25A38 predicted poor clinical outcomes not only in all patients but also in patients without metastasis or patients with disomy 3 in TCGA UM cohort. AUC Area Under Curve.
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PMC9001737
|
41419_2022_4718_Fig2_HTML.jpg
|
0.389631 |
c6137cee572c400c9dcc2dc9eb9c708c
|
SLC25A38 is the upstream of several metastasis-related pathways.A Pie chart illustrating differentially expression genes between SLC25A38-low tumors and SLC25A38-high tumors in TCGA UM RNA-seq dataset. B GSEA showing that SLC25A38 expression was negatively correlated with proliferative and metastatic gene signatures in the TCGA UM dataset. C Heatmap showing differentially expression genes in UM cells with SLC25A38 knock-out relative to control cells. D The most significant differentially GO items upon SLC25A38 knock-out. E Differentially expression genes in the SLC25A38-silenced UM cells in the indicated signaling pathways analyzed by qRT-PCR. F These series of networks demonstrated the changes in SLC25A38 and its neighboring genes (involving in cell proliferation, cell adhesion, cell motility, and angiogenesis) in terms of expression during metastasis in TCGA UM specimens and GSE22138 tumors.
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PMC9001737
|
41419_2022_4718_Fig3_HTML.jpg
|
0.435312 |
5bc9ca74ce5349e4adf3aac196ca7592
|
Silencing SLC25A38 promotes the malignant properties of UM cells in vitro and in vivo.A UM cells with SLC25A38 knock-out were successfully constructed. B, C Wound healing assay (B) and transwell invasion assay (C) showing that SLC25A38 knock-out could enhance the migration and invasion ability of UM cells. D Vascular ring formation analyses indicate the increasing ability of angiogenesis upon SLC25A38 knock-out. The number of tubes was counted and normalized tube length was calculated, scale bar 100 μm. E PET imaging and H&E staining showed that mice inoculated with SLC25A38 knock-out UM cells had more lung metastases and live metastases compared to that injected with control UM cells, scale bar 100 μm.
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PMC9001737
|
41419_2022_4718_Fig4_HTML.jpg
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0.424344 |
0c09c0e83d57474a86e367edf1f3f27f
|
Downregulated SLC25A38 boosts angiogenesis.A A proposed model underlying the role of SLC25A38 in UM angiogenesis. Through the promotion of the coactivator (CBP/p300) of HIF upon SLC25A38 knock-out, its target genes including pro-angiogenic factors are overexpressed and thus promote angiogenesis. GSEA of TCGA cohort and PCR validation of UM cells verified this proposal. B Correlation between SLC25A38 and CBP or CD31 protein expression in UM specimens. Tumor sections from 28 UM specimens were immunofluorescence stained with anti-SLC25A38, anti-CBP, and anti-CD31 antibodies. Left: representative images. Right: the correlation between SLC25A38 and CBP or CD31 protein expression was calculated by Pearson correlation coefficient. C Correlation between SLC25A38, CBP, FGF8, FGF12, TGFα, and CD31 expression in TCGA UM RNA-seq dataset. The Pearson correlation coefficient and P-value are indicated.
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PMC9001737
|
41419_2022_4718_Fig5_HTML.jpg
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0.471873 |
e7c2a4dbe45645119cbbb2ed31d8cb55
|
Simple illustration of factors; sleep quality; care burden and social isolation affecting informal caregivers of person with dementia.
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PMC9002108
|
fpubh-10-797176-g0001.jpg
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0.387158 |
cc6368c71f0d4de3a5eac06cec2029ee
|
Flowchart of the screening process of the literature (*, added via Snowball-method).
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PMC9002108
|
fpubh-10-797176-g0002.jpg
|
0.380227 |
63e0c300f49243f4a35030fe92928042
|
Chemical fractionation general procedure.
|
PMC9002365
|
polymers-14-01333-g001.jpg
|
0.473004 |
5326451f1bc043fa9e9b523ab7078316
|
Interaction of reaction temperature, time and pH on the total removal rate of AAEMs. ((a), interaction between temperature and time on the total removal rate of AAEMs. (b), interaction between temperature and pH on the total removal rate of AAEMs. (c), interaction between pH and time on the total removal rate of AAEMs. (d), fitting relationship between the predicted value and the experiment value).
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PMC9002365
|
polymers-14-01333-g002.jpg
|
0.475818 |
75720e167e6b4ea49d389fbc7de80b69
|
TG (a) and DTG (b) of eucalyptus with or without acid leaching and hydrothermal pretreatment.
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PMC9002365
|
polymers-14-01333-g003.jpg
|
0.395704 |
c5a844577c524889bc5fabbda4926612
|
Composition and distribution of pyrolytic bio-oil from different eucalyptus samples (a–c), components of pyrolytic bio-oil from raw material, acid leaching eucalyptus and hydrothermal pretreatment eucalyptus. (d–f), distribution of pyrolytic bio-oil from raw material, acid leaching eucalyptus and hydrothermal pretreatment eucalyptus.
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PMC9002365
|
polymers-14-01333-g004.jpg
|
0.422068 |
a882507283e14c728c12046b550d3d56
|
Forms of main metal elements in eucalyptus before and after hydrothermal pretreatment and acid leaching ((a), contents of K, Ca and Mg in different eucalyptus samples. (b), contents of K in different forms in eucalyptus after acid pickling and hydrothermal pretreatment. (c), contents of Ca in different forms in eucalyptus after acid pickling and hydrothermal pretreatment. (d), contents of Mg in different forms in eucalyptus after acid pickling and hydrothermal pretreatment).
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PMC9002365
|
polymers-14-01333-g005.jpg
|
0.416122 |
dd67036345ff4a52a4fe80cba3e52370
|
(a) The Nucleo L476RG + IKS01A1, (b) the ST-Qvar board, and (c) the Bluetooth module.
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PMC9002930
|
sensors-22-02566-g001.jpg
|
0.433865 |
66e1f7878f424ec3b675524551453088
|
Pre-amplifier circuit.
|
PMC9002930
|
sensors-22-02566-g002.jpg
|
0.480082 |
7b8f451db42246129361958b0c8ef66c
|
(a) The detailed high−pass filter; (b) gain vs. frequency.
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PMC9002930
|
sensors-22-02566-g003.jpg
|
0.457163 |
7d659db5168a4d91af07baba4ac768bb
|
Simulations of the differential stage performed on LT Spice: (a) Differential gain; (b) common−mode gain.
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PMC9002930
|
sensors-22-02566-g004.jpg
|
0.401464 |
bb934a95bf4746ff807051a33c0b374e
|
Noise analysis of the proposed pre-amp stage with Zep = ∞.
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PMC9002930
|
sensors-22-02566-g005.jpg
|
0.465812 |
df432eb4241a4f399ce738d407911698
|
Electrode model according to IEC 60601–2–47 standard.
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PMC9002930
|
sensors-22-02566-g006.jpg
|
0.433749 |
361c0149aaa34fdc8a86ee193facba98
|
Noise analysis of the proposed pre-amp stage with Zep = 0.
|
PMC9002930
|
sensors-22-02566-g007.jpg
|
0.431707 |
088f3d30dd0a4a09a73953f3db6f71a4
|
Monte Carlo simulations on pre−amplifier stage with 1% passive tolerance.
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PMC9002930
|
sensors-22-02566-g008.jpg
|
0.442491 |
0ad40e4de972411d920f33198de0c063
|
Matlab application interface for data acquisition.
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PMC9002930
|
sensors-22-02566-g009.jpg
|
0.489552 |
92a3d87caf034ee78a62d8fd5aeffd5f
|
Block diagram of the proposed firmware. The overall system clock is 3 MHz and the interrupt clock is 240 Hz.
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PMC9002930
|
sensors-22-02566-g010.jpg
|
0.446947 |
8b25fd0dd8ac4acd9f184c415db7b961
|
(a) Electrodes positioning; (b) typical ECG raw trace.
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PMC9002930
|
sensors-22-02566-g011.jpg
|
0.471643 |
f9a1fed6714c4259b726f7f58a8f69f8
|
(a) Filtered ST−Qvar ECG: single oscillation; (b) Typical ECG, single oscillation.
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PMC9002930
|
sensors-22-02566-g012.jpg
|
0.468721 |
369d32a26c9e41758ea442fc71ea6029
|
ECG trace acquired simultaneously from Qvar and MicroMed systems, from different derivations. Dashed lines show the R−peaks correspondence between the two tests.
|
PMC9002930
|
sensors-22-02566-g013.jpg
|
0.434419 |
941c42758a124b37a4e4df122bd2f446
|
Electrodes positioning for EEG–EOG test for MicroMed (left, orange electrodes) and ST-Qvar (right, blue electrodes).
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PMC9002930
|
sensors-22-02566-g014.jpg
|
0.406035 |
978ae9dc9d4c4726ada7b00d3400d9af
|
MicroMed vs. ST−Qvar raw traces from frontal single-channel EEG acquisition.
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PMC9002930
|
sensors-22-02566-g015.jpg
|
0.45057 |
12f10c86d2a74e2fac1eb09ba2b4736e
|
Cross-correlation between ST−Qvar and MicroMed acquisitions. MicroMed signal autocorrelation.
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PMC9002930
|
sensors-22-02566-g016.jpg
|
0.43816 |
5aa753583a7b4a6097679643373862bc
|
EOG trace recorded from ST−Qvar and the gold standard during clockwise eye movements. A single window of the eye movements is highlighted with a rectangle.
|
PMC9002930
|
sensors-22-02566-g017.jpg
|
0.404617 |
d9a0f971a98143cba22ffe7af101fdbb
|
EOG trace recorded from ST−Qvar and the gold standard during eye blinking test. Each peak represents an eye blink.
|
PMC9002930
|
sensors-22-02566-g018.jpg
|
0.517529 |
5be969f4cef442379b00201623d13ef3
|
Changes in (A) mechanism and (B) diagnosis leading to IF over the study period, presented on a mosaic plot where the size of the squares represents the proportion of all included patients. IF, intestinal failure; SBS, Short bowel syndrome.
|
PMC9003376
|
nutrients-14-01449-g001.jpg
|
0.493531 |
39352d2c246d4eb9bb2e67ce2a5b8fd0
|
Cumulative incidence function of achieving nutritional autonomy.
|
PMC9003376
|
nutrients-14-01449-g002.jpg
|
0.47625 |
fe7c39f22c1840c8941152f610fa1903
|
Relationship between mechanism of IF at HPN initiation, subsequent surgery and achieving nutritional autonomy. HPN, Home Parenteral Nutrition.
|
PMC9003376
|
nutrients-14-01449-g003.jpg
|
0.421173 |
c28dab9d95bf43c0869935f3aff48587
|
An UpSet plot to illustrate the distribution of reasons for not achieving nutritional autonomy in patients predicted to do so. The x-axis shows possible reason combinations. Each filled-in node shows an identified reason, with the vertical lines linking each reason within the combination. The frequency of each reason combination is shown along the y-axis, correlating to the number of patients with identified reasons as shown by the filled-in nodes. Set size represents the overall frequency of each reason.
|
PMC9003376
|
nutrients-14-01449-g004.jpg
|
0.375574 |
b977fe72946543f1978a6a592adb44ff
|
Percentage frequency distributions that specify the percentage of observations that exist for each relevance (solid colors) and frequency (dashed colors) levels defined hereunder for each SSE advanced to round 2. The 75% agreement threshold line also confirms the relevance of the SSE included in the final inventory. *ER = external rotation
|
PMC9003989
|
40945_2022_132_Fig1_HTML.jpg
|
0.429399 |
cf6ae62c71e348e59d1e8de5411f0e0f
|
Distribución de la población de acuerdo con el género y el grupo etario.
|
PMC9005167
|
6936AX212-ACM-92-174-g001.jpg
|
0.423589 |
0829f06c71314588b1b371520e356933
|
Mapa del Paraguay con el porcentaje de pacientes derivados de los departamentos y la ubicación geográfica de los hospitales participantes.*Instituto Nacional de Cardiología, Instituto de Previsión Social.**Hospital de Cínicas, Hospital Nacional de Itauguá.
|
PMC9005167
|
6936AX212-ACM-92-174-g002.jpg
|
0.507694 |
7b12efbe2c3644ec9eee1a4db862285c
|
Age standardized death rate due to stroke at the county level in the United States in 2014.
|
PMC9005481
|
ccdcw-4-13-280-1.jpg
|
0.395394 |
b30e2b5237ed45d8beece32384ab5132
|
Global distribution of country level mortality due to stroke in 2040.
|
PMC9005481
|
ccdcw-4-13-280-2.jpg
|
0.568665 |
c45dc955edd34f10bc3d62a08bb285d3
|
The developmental outcome and treatment effects to oxcarbazepine of epilepsy patients with SCN2A variants. A total of 59 SCN2A variants was included. The shapes of variation sites represent different variation types (circle = missense variation; triangle = nonsense variation; square = frameshift variation; rhombu = in-frame deletion variation). The colors of the shape represent different developmental outcome (red = developmental delay; green = normal development; orange = both patients with normal development and developmental delay were observed). The colors of the variants represent the treatment effects of oxcarbazepine (green = seizure freedom; blue = seizure reduction; orange = no effect; red = seizure worsening; black = never used). The variation underlined indicates fever-sensitivity. Pentagons indicate one patient with the variants died.
|
PMC9005871
|
fnmol-15-809951-g001.jpg
|
0.440334 |
8d598b60ebc9461da9c1ab2c34abd6e1
|
Abnormal brain MRI of 3 patients with SCN2A variants. Brain MRI of Patient 14 at the age of 22 months. (a,b). Axial and coronal images (T1WI) showing agenesis of corpus callosum, delayed white matter myelination, dysplasia of frontotemporal lobes and enlargement of lateral ventricles. Brain MRI of Patient 29 at the age of 7 months. (c,f) Sagittal images (T1WI) showing enlargement of lateral ventricles, agenesis of corpus callosum and dysplasia of frontotemporal lobes. Brain MRI of Patient 39 at the age of 12 months. (d,e) Axial and coronal images (T2WI) showing agenesis of corpus callosum, delayed white matter myelination and enlargement of lateral ventricles. The arrow points to the lesion.
|
PMC9005871
|
fnmol-15-809951-g002.jpg
|
0.393628 |
b31312bec6654d518c017e1ea0b7db28
|
Distribution of 72 Chinese epilepsy patients with SCN2A variants according to phenotypes [n (%)].
|
PMC9005871
|
fnmol-15-809951-g003.jpg
|
0.413795 |
fc5ee4d7bfb1422b98b7ea8d667db740
|
Treatment effects of anti-seizure medication (ASM) therapies in epilepsy patients with SCN2A variants. Number of treated patients and their seizure outcome (green = seizure freedom; blue = seizure reduction; orange = no effect; red = seizure worsening) that have been treated with different ASM therapies. Only effects of ASM therapies that at least one patient achieved seizure free are shown. OXC, oxcarbazepine; CBZ, carbamazepine; LTG, lamotrigine; VPA, valproate; TPM, topiramate; LEV, levetiracetam; PB, phenobarbital; VGB, vigabatrin; PRP, perampanel.
|
PMC9005871
|
fnmol-15-809951-g004.jpg
|
0.470518 |
de8af881802a4f35b8b76264383a3819
|
Diagrams of the three a priori candidate structural equation models depicting different phenotypic covariance structures between the pace-of-life and thermal performance: (a) ‘coupled pace-of-life syndrome–thermal performance’ model, (b) ‘independent pace-of-life syndrome and thermal performance’ model and (c) ‘overarching thermal pace-of-life syndrome' (c). Observed variables are given in rectangles, unmeasured latent variables in ellipses. See main text for details.
|
PMC9006028
|
rspb20212414f01.jpg
|
0.456805 |
6f483015aab84fe5b6db785884fdcfec
|
Effects of latitude and rearing temperature on the trait means (±1 s.e.) for (a) growth rate, (b) activity, (c) boldness and (d) metabolic rate. (Online version in colour.)
|
PMC9006028
|
rspb20212414f02.jpg
|
0.418618 |
e6fcb1d4278140ad887757c6ecd7ba5c
|
Thermal performance curves of (a,b) activity, (c,d) boldness, (e,f) metabolic rate and (g,h) swimming speed, as a function of rearing temperatures and latitudes. Solid (blue) curves are for high-latitude larvae; dashed (red) curves are for low-latitude larvae. Bands around curves represent 95% CIs. (Online version in colour.)
|
PMC9006028
|
rspb20212414f03.jpg
|
0.452009 |
0f058c02987944ea92ba4c970bca4be3
|
SEM diagram depicting the supported ‘coupled pace-of-life syndrome–thermal performance’ model. Numbers associated with single-headed arrows are standardized path coefficients. Double-headed arrows indicate correlations. All loadings were significant (p < 0.05) with the exception of growth rate (dotted arrow, p = 0.068). Red arrows indicate negative path coefficients; black arrows indicate positive path coefficients. (Online version in colour.)
|
PMC9006028
|
rspb20212414f04.jpg
|
0.416507 |
9dca1452243a4bd09c6159e9b373a84c
|
Study procedures and timeline. Items in bold denote data collection.
|
PMC9006806
|
bmjopen-2021-050951f01.jpg
|
0.501532 |
d1488cc49ab74d7fac65ac52dc848cfc
|
Flow chart showing the identification and enrolment of participants into the study. AF, atrial fibrillation; ASCVD, atherosclerotic cardiovascular disease; DLCN, Dutch Lipid Clinic Network; FH, familial hypercholesterolaemia; LDL-C, low-density lipoprotein cholesterol; LLT, lipid-lowering treatment.
|
PMC9006835
|
bmjopen-2021-050857f01.jpg
|
0.540827 |
a11f912196b84c958d6b72aa76160913
|
Flow diagram showing screening and enrolment of study population. *Age less than 18 years. †Age 18 years or more. Note: RT-PCR = reverse transcription polymerase chain reaction.
|
PMC9007444
|
cmajo.20220026f1.jpg
|
0.404481 |
5cba339eb38a4710ad7b4e193d55bbfa
|
Risk factors for household transmission. Note: CI = confidence interval, HC = household contact, I = index participant, OR = odds ratio.
|
PMC9007444
|
cmajo.20220026f2.jpg
|
0.449118 |
8eb4365401c14f26a395f9a44276e094
|
Electronic
spectra of C2n+–He observed by monitoring
the wavelength dependent loss of the helium atom. The data are believed
to be the lowest energy doublet transitions of monocyclic cation ring
structures.
|
PMC9007455
|
jp2c00650_0001.jpg
|
0.445292 |
3d5f2c2b93fd4876bb55c6c9f87f7ad0
|
Wavelengths of origin
band maxima as a function the number of carbon
atoms (black). A linear fit to these wavelengths is the red line.
|
PMC9007455
|
jp2c00650_0002.jpg
|
0.461564 |
5b6458d3446144c8ba00f32d5318244a
|
Electronic
spectra of monocyclic cations plotted as a function
of energy Δν̅ from the origin band. The data are
separated into 4n + 2 (left) and 4n (right) series.
|
PMC9007455
|
jp2c00650_0003.jpg
|
0.54476 |
e6d9a48536554d7283766b9c632e76f2
|
Lowest energy portion of the C28+–He
spectrum. The profile suggests
more than one unresolved component and has been fit with three Lorentzian
functions (red); the cumulative result is the dotted line.
|
PMC9007455
|
jp2c00650_0004.jpg
|
0.474098 |
a882425621e9431791a12b0e1ff59d50
|
Electronic
spectra of monocyclic cations tagged with one (black)
and two (red) helium atoms. The data are separated into 4n + 2 (left) and 4n (right) series.
|
PMC9007455
|
jp2c00650_0005.jpg
|
0.414214 |
05ae2929d33d4453b1732600c3260413
|
(A) Distribution of Cq in the URT and LRT samples. (B, C) Differences and correlation plots for Cq values in 28 paired URT and LRT samples. The statistic Spearman's correlation coefficient and linear regression R2 value are also reported.
|
PMC9008095
|
gr1_lrg.jpg
|
0.410332 |
4f79eed2cc9f4330b8d9b2b59995a5e0
|
Comparison of number of haplotypes and minority variants in upper vs lower respiratory tract samples. (A) Correlation between the number of minority variants and viral load expressed in cycle of quantification (Cq). (B) Correlation between the number of haplotypes and viral load expressed in Cq.
|
PMC9008095
|
gr2_lrg.jpg
|
0.411639 |
972f93b8dcb64e029df23f6e1269d7a1
|
Distribution of the number of (A) minority variants, (B) haplotypes and (C) dN/dS ratio in the URT and LRT samples. Values are represented as a boxplot with all points inscribed. (D) Distribution of the weighted incidence of synonymous, non-synonymous, and insertions and deletions (Indel) in the URT and the LRT samples. (E) Distribution of the weighted incidence of frameshifting insertions and deletions in the URT and the LRT. Values are weighted by dividing them by the total number of minority variants in the sample.
|
PMC9008095
|
gr3_lrg.jpg
|
0.376138 |
682523666f874283a44685119f6dc0fa
|
(A) Distribution of the weighted incidence of minority variants in the S gene subdomains (NTD: N-Terminal Domain; RBD: Receptor-Binding Domain; SD1: Structural Domain 1; SD2: Structural Domain 2; FP: Fusion Peptide; HR1: Heptad Repeat 1; HR2: Heptad Repeat 2; TM: TransMembrane domain) in the URT and LRT samples. (B) Distribution of the weighted incidence of minority variants in the two S gene subunits in the URT and the LRT (S1: Subunit 1; S2: Subunit 2). (C) Distribution in the URT and in the LRT of the weighted incidence of minority variants, classified by mutation patterns. Values are weighted by dividing them by the total number of minority variants in the sample.
|
PMC9008095
|
gr4_lrg.jpg
|
0.461446 |
36f709d3fc714a4e8381ac70474bf3ad
|
Graphical distribution of changes along S protein gene. (A) Number of samples containing minority variants in each position. Two separate histograms are used for URT and LRT samples, which are indicated upside down for image clarity. (B) Correlation of the presence of minority variants with URT and LRT in each position of the gene. Bar height represents the log10 (p-value) of the Fisher exact test. In the middle, a scheme of the gene subdomains and subunits is used as separator. NTD: N-Terminal Domain; RBD: Receptor-Binding Domain; SD1: Structural Domain 1; SD2: Structural Domain 2; FP: Fusion Peptide; HR1: Heptad Repeat 1; HR2: Heptad Repeat 2; TM: TransMembrane domain; S1: Subunit 1; S2: Subunit 2.
|
PMC9008095
|
gr5_lrg.jpg
|
0.453412 |
fdf554fc782843acb7fc7786da72e93e
|
Replication analysis in wild-type (WT) and pykA null cells growing exponentially in MC medium. A Schematic representation of CCM. Glyco: Glycolysis; Gluco: gluconeogenesis; PPP: pentose phosphate pathway; TCA: tricarboxylic acid cycle; O: overflow pathway; G3P: glyceraldehyde 3-phosphate; PEP: phosphoenolpyruvate; Gray arrows: carbon flux; Thick bars: CCM area genetically linked to replication genes [42, 44]. B Growth rate and pyruvate kinase activity. Cells were grown exponentially for more than 20 generations using successive dilutions. Growth was assessed by spectrophotometry (OD650nm, a typical experiment is shown) and pyruvate kinase activity was determined in crude extracts (mean from six independent experiments). C
Ori/ter ratio: Ori/ter ratios were determined by qPCR using as template total DNA extracted from growing cells. Numbers in brackets stand for the number of independent measurements. The Mann-Whitney U test showed that the ratios in wild-type and ΔpykA cells are significantly different at p < .05 (Table S1). D DNA elongation: Parameters of DNA elongation were determined using a marker frequency analysis by qPCR. The nearly monotonous decrease of marker frequencies from the origin to the terminus showed that there is no pause site along the chromosome (a typical experiment is shown). Numbers in brackets refer to C period (mean and SD from at least 3 experiments) and mean fork speed. E Number of origins per cell: To determine the number of origins/cell, chloramphenicol was added to exponentially growing cells. The drug inhibits replication initiation and cell division but allows completion of ongoing rounds of replication. After 4 h of drug treatment (runout experiment), cells were analyzed by flow cytometry after DNA staining. Panels: typical runout DNA histograms with the % of cells containing 4 and 8 chromosomes. Numbers in brackets stand for the number of independent reiterations of the experiment. The number of origins/cell (mean and SD) is given below the strain name. See “Methods” for details
|
PMC9009071
|
12915_2022_1278_Fig1_HTML.jpg
|
0.381983 |
612b50fd92df4b339b98912f53a154ae
|
Ori/ter ratios and PykA catalytic activities in Cat and PEPut mutants. Ori/ter ratios were grouped (color code) according to the Mann-Whitney U test at a significance of p < 0.01 (see Table S1 for details). Numbers in brackets refer to the number of independent iterations. The horizontal gray bars highlight the wild-type ratio area. Pyruvate kinase activities (bolded numbers expressed in % of wild-type activity) in crude extracts were determined from at least three independent experiments (SD/means < 10%). A Cat mutant analysis. B PEPut mutant analysis. See Fig. 1 for details
|
PMC9009071
|
12915_2022_1278_Fig2_HTML.jpg
|
0.472934 |
e68ba84e37144e1f842b66c35d6966ed
|
Metabolome analysis of wild-type and pykA mutants in MC. A, B PCA scores plots (first two components) in the positive (A) and negative (B) ionization mode. Ellipses are the 95% confidence regions. Indicated are the relative activities of PykA. Data correspond to 4 independent extractions (liquid cultures). C Comparison of PykA substrate and product contents in pykAT>D and wild-type (WT) cells. D Comparison of the contents of compounds annotated as pseudaminic acid (Pse) and CMP-pseudaminic acid (CMP-Pse) in pykAT>D and wild-type cells. Data in C and D correspond to 3 independent extractions (solid cultures).*, p > 0.05 ; **, p < 0.01 (Welch’s T-test). Values in bold panels C and D indicate the fold change for each metabolite (wild-type versus pykAT>D)
|
PMC9009071
|
12915_2022_1278_Fig3_HTML.jpg
|
0.452466 |
b8b21f07f1534241af6a0db2e18018bf
|
Primarily replication defect in pykA mutants. Ori/ter ratios were measured in cells replicating the chromosome from a plasmid replicon instead of the natural chromosomal replication origin. See Fig. 1 for details
|
PMC9009071
|
12915_2022_1278_Fig4_HTML.jpg
|
0.490897 |
f9ca490884de409da6caac1d76f4ac6f
|
Cell cycle and replication pattern of wild-type, pykAGD245/6AA and pykAT>D cells. Vertical red lines stand for three successive generations: grandmother: 0τ to 1τ; mother: 1τ to 2τ; daughter: 2τ to 3τ; 28.4 min each). The C and D periods of cell cycles ending at time 1τ, 2τ, and 3τ are indicated as lines and boxes colored in black, blue and yellow, respectively. The cell cycle in green will end at time 4τ (not shown). Gray areas refer to replication periods spanning every cell cycle and numbers correspond to the proportion of cells in each period. Replication patterns typifying each period are given above the gray areas using the cell cycle color code. Ai: age of replication initiation; At: age of replication termination. Activity stand for pyruvate kinase activity
|
PMC9009071
|
12915_2022_1278_Fig5_HTML.jpg
|
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