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0.399027
2f16383ca8e74d1ebe6e91ce86c0f75b
Four types of model tests (left) and four types of evaluation metrics (right).
PMC9353319
gr14_lrg.jpg
0.421715
a4dccfbb53c240b9b9a4f63c0e7bca6a
Accuracy verification methods with extreme values.
PMC9353319
gr15_lrg.jpg
0.388643
7b46f95e3eef435490cecc7ace85854b
The interplay between urban spatial risk and urban design.
PMC9353319
gr16_lrg.jpg
0.470929
cf37c646ec5e4abbb64fc6952d0b5955
Correlation superposition classification analysis of elements.
PMC9353319
gr17_lrg.jpg
0.451284
8f79cccc922b4b5f8ecf4b8a079da8b7
Two-class element superposition mode.
PMC9353319
gr18_lrg.jpg
0.452246
f4118b17a2d448b9aa01d6473276fe97
Three-class element superposition mode.
PMC9353319
gr19_lrg.jpg
0.520935
d25619d40fea4ceba9eb248aee6499cf
Statistics for daily new infections in Wuhan.
PMC9353319
gr1_lrg.jpg
0.411619
e8bd1233b67c4524a7ddfce1c0ac9e7c
Five-class element superposition mode.
PMC9353319
gr20_lrg.jpg
0.432667
1259ebc51b1c48dca8e8a0e2370dff08
Predicting POI facilities based on urban maps.
PMC9353319
gr21_lrg.jpg
0.429504
efc0e3d554054854abc4255fd396a100
Using generative models to predict the incidence of Shanghai City.
PMC9353319
gr22_lrg.jpg
0.454378
8d95320898f545feb4dc16035fcecf4e
Thermal and spatial risk factors of the epidemic in Wuhan.
PMC9353319
gr2_lrg.jpg
0.437628
f1e435eae7254562a2f94891bdf4a47f
Top: Semi-variogram of kriging interpolation model. Bottom: Search neighborhood graph.
PMC9353319
gr3_lrg.jpg
0.450032
13d2e4c3ed7f4ead924969349fd4b279
Population density.
PMC9353319
gr4_lrg.jpg
0.439506
3d3b4ad7e3674e9fb6b4f36f25d2c50a
Incidence rate.
PMC9353319
gr5_lrg.jpg
0.508688
61181d31c57f4b1d80467a5fb403c38b
Sample labels of incidence rate.
PMC9353319
gr6_lrg.jpg
0.450048
006223bbbed0485ab109352a6b98eb01
Density distribution of COVID-19 spatial risk factors in Wuhan.
PMC9353319
gr7_lrg.jpg
0.397451
d6c8c187fce542e9ab240bde7b286806
Measurement of correlation coefficient.
PMC9353319
gr8_lrg.jpg
0.487316
5486b533005e46dea299f5901452a601
Processing of features and labeled samples.
PMC9353319
gr9_lrg.jpg
0.386648
740f5530497b440f92777d6c172e80b5
Frequency of antiviral medicine prescription by date for coronavirus disease 2019 among outpatient individuals that recently tested positive for severe acute respiratory syndrome coronavirus 2 from March 31, 2022 to July 8, 2022 (n = 1216)
PMC9353369
JMV-9999-0-g001.jpg
0.440841
ac7f5a1cc7db4b17b758741a2c93a611
a) Schematic of the opaque and semi‐transparent (ST) perovskite solar cell (PeSC) device structures. DMD represents the semi‐transparent dilelectric‐metal‐dielectric electrode used in ST‐PeSCs. b) Photograph of perovskite devices, demonstrating color tunability through control of the cation (MA, FA, and Cs) and halide (iodide and bromide) compositions in the perovskite crystal structure. c) V oc as a function of the perovskite band gap for perovskite devices using CsFAMA (black), CsFA (red), and MA (blue) A‐site cations. Selected V oc values from the literature are shown as empty circles and a linear fit to these is shown by the black line.[ 20 , 22 ] The solid red line corresponds to 90% of the V oc in the Shockley–Queisser (S–Q) limit.
PMC9353478
ADVS-9-2201487-g002.jpg
0.402379
a077b49a15a74ab2aa00009f507ef60a
SEM images of the surfaces of perovskite films of various cation composition (CsFAMA1‐4, CsFA1‐4, and MA1‐4) and their band gaps (1.63–1.92 eV).
PMC9353478
ADVS-9-2201487-g003.jpg
0.424167
9cfa9dd8087745be90e8e58aa282139a
Stability characteristics of encapsulated ST‐PeSCs with various perovskite cations under a) continuous one‐sun illumination and MPP tracking and b) during thermal stability testing at 85 °C in ambient air. c) Effect of solution aging on PCE of PeSCs based on various cations. 1H NMR spectra of the perovskite precursor solutions when freshly prepared or aged for 10 days: d) CsFAMA‐2, e) CsFA‐2, and f) MA‐2.
PMC9353478
ADVS-9-2201487-g004.jpg
0.508177
f712feb0753e4a72b7cc7d01de9db4ab
a) J–V characteristics for hole‐only (ITO/PEDOT:PSS/perovskite/VNPB/Au) and b) electron‐only devices (ITO/SnO2/perovskite/PCBM/Ag) with various perovskite compositions. c) Nyquist plots of ST‐PeSCs with various perovskite compositions. The inset figure shows the equivalent circuit model for PeSCs. d) Transient absorption decay probed at the band edge for various perovskite compositions.
PMC9353478
ADVS-9-2201487-g005.jpg
0.435036
8f5c84ed1cdf4d23b8e4edcd779759d1
a) Dependence of LUE (PCE × AVT) values of ST‐PeSCs on perovskite film thickness. The solid lines show the predicted values based on 90% of the V oc in the Shockley–Queisser (S–Q) limit. The inset shows photographs of the CsFA‐2 and ‐3‐based ST‐PeSCs with 100 nm thickness (with the National Gallery of Victoria (NGV) and Flinders Street Station in Melbourne in the background). b,c) LUEs and PCEs against AVTs of our ST‐PeSCs compared to our previous work and with literature (see Table S5, Supporting Information for details).[ 4 , 5 , 28 ] All AVT values presented in this graph were determined over the 400–800 nm range. Solid lines show the maximum predicted device performance for devices operating at 90% of the performance given by the Shockley–Queisser (S–Q) limit across all band gaps. Meanwhile, the dashed line shows the predicted performance characteristics for 1.73 eV (red) and 1.81 eV (black) band gaps. d) Color coordinates on the CIE 1931 chromaticity diagram of the ST‐PeSCs with different perovskite thicknesses.
PMC9353478
ADVS-9-2201487-g006.jpg
0.437315
de113ca2e82c41088fc222d7c663d70d
Maximum theoretical efficiency of ST‐PeSCs based on LUE (PCE × AVT(%)) with PCE values calculated using V oc values of a) 90% of the V oc in the S–Q limit and b) literature limits of the band gap‐dependent V oc.
PMC9353478
ADVS-9-2201487-g007.jpg
0.488477
4b1977b8e1464507a3982a60fb67f83a
Research workflow. The input data for the study were a set of BAM files with the results of mapping DNA reads to the reference genome, a BED file containing the coordinates of the sequencing regions in WES, and the DNA sequence of the reference genome. The depth of coverage was counted using 7 strategies implemented in CANOES, CODEX, exomeCopy, ExomeDepth, CLAMMS, CNVkit, and CNVind. As a result of the depth of coverage counting, we obtained 7 other tables containing the depth of coverage in a given sequencing region for each sample. The resulting tables were used as input to the appropriately modified CANOES, CODEX, exomeCopy, ExomeDepth, CLAMMS, CNVkit, and CNVind tools to detect CNVs. As a result of the 7 CNVs callers’ operation, we obtained 49 result sets of CNVs—7 CNVs calling tools were run 7 times, each time using a different table with the depth of coverage. CNV indicates copy number variation; WES, whole-exome sequencing.
PMC9354125
10.1177_11779322221115534-fig1.jpg
0.433746
7f63550319a742c5ab7d686b5b7d2ff8
Comparison of the results of counting the depth of coverage with different tools. The figure presents the box plot (A) and course changes in the depth of coverage values (B) for chromosome 11 of the NA06984 sample. First, statistics of the counted depth of coverage values for each tool are different (A). Second, an interesting observation is that the other behavior of different counting depth of coverage strategies in the following sequencing regions. CNV indicates copy number variation.
PMC9354125
10.1177_11779322221115534-fig2.jpg
0.382902
1896587105d4410c9391907397761467
Comparison of the results obtained by the CANOES, CODEX, exomeCopy, ExomeDepth, CLAMMS, CNVkit, and CNVind applications for chromosome 1 data set. The diagram shows the evaluation of the resulting CNVs sets for the CANOES (A), CODEX (B), exomeCopy (C), ExomeDepth (D), CLAMMS (E), CNVkit (F), and CNVind (G) tools. Each of the tools was run 7 times with different input depth of coverage tables counted by other methods (the 7 strategies for counting the depth of coverage tested in the experiment were shown in different colors). Each of the result sets of detected CNVs was divided based on frequency (common and rare) and length (short and long). The number of FP calls is presented on the vertical axis, and the number of TP calls on the horizontal axis. It is worth noting that for all applications, the results obtained using the coverage table from the CODEX and CNVind tools are identical—the CODEX and CNVind tools calculate the coverage depth in the same way. CNV indicates copy number variation; FP, false positive; TP, true positive.
PMC9354125
10.1177_11779322221115534-fig3.jpg
0.400805
82b45206310c48f59ad609d5d3e4ae12
Comparison of the results obtained by the CANOES, CODEX, exomeCopy, ExomeDepth, CLAMMS, CNVkit, and CNVind applications for chromosome 11 data set. The diagram presents a comparison of the different results of CNVs detected by another tool and with different input depth of coverage tables. The following panels show the results for the CANOES (A), CODEX (B), exomeCopy (C), ExomeDepth (D), CLAMMS (E), CNVkit (F), and CNVind (G) tools, and different algorithms for counting the depth of coverage are marked with other colors. CNV indicates copy number variation; FP, false positive; TP, true positive.
PMC9354125
10.1177_11779322221115534-fig4.jpg
0.501115
2fa358bf94e947a9a6afc057e804296b
The serum levels of IL-18 in patients with depression and healthy people in the Peripheral blood. MDD: major depressive disorder, Control: healthy control; **: < 0.01
PMC9354267
12888_2022_4176_Fig1_HTML.jpg
0.517609
4ae56360ca9f404f89cb6d8cba42227e
Correlation between IL-18 levels and DC in patients with depression and healthy people in the whole brain. Blue clusters are the brain area with negative correlation. MDD: major depressive disorder, HC: healthy control; L: left hemisphere; R: right hemisphere
PMC9354267
12888_2022_4176_Fig2_HTML.jpg
0.535915
74206ab4602b43fe81698cbea2289266
IL-18 and DC in brain imaging of patients with depression
PMC9354267
12888_2022_4176_Fig3_HTML.jpg
0.476774
35a5dbd565db4ff19b351050977d08d3
Detailed workflow of this study.
PMC9354608
fgene-13-906496-g001.jpg
0.44423
ba2af5b79b6b4c25923d428e70a869ec
Identification of m7G-related lncRNAs in LIHC patients. (A) Heatmap showed the differences in the expression of m7G regulators between LIHC and normal groups. (B) Sankey diagram displayed the relationship between 22 m7G genes and 992 m7G-related lncRNAs.
PMC9354608
fgene-13-906496-g002.jpg
0.438767
9b76b918b705432987ff16fc33045d48
Construction of a m7G-related lncRNA risk model for LIHC patients. (A) Forest plot showed 41 prognostic lncRNAs screened via univariate regression analysis. (B) LASSO regression of 20 m7G-related lncRNAs. (C) Cross-validation in LASSO regression. (D) Forest plot displayed 9 m7G-related lncRNAs selected by multivariate regression analysis. (E) PCA based on entire LIHC gene expression profiles in the two groups. (F) PCA based on 22 m7G regulator gene expressions in the two groups. (G) PCA based on 992 m7G-related lncRNA expressions in the two groups. (H) PCA based on 9 prognostic m7G-related lncRNA expressions in the two groups.
PMC9354608
fgene-13-906496-g003.jpg
0.474307
ea6d07292bfb4507ab33ff976d974659
Prognostic value of the 9-m7G-related-lncRNA risk model between the two groups in the training set. (A) Distribution of the risk score (the x-axis represented the LIHC patients arranged according to the risk score, and the y-axis represented values of the risk score for each patient). (B) Scatter plot of survival status and risk score (the x-axis represented the LIHC patients arranged according to the risk score, and the y-axis represented the survival time of each patient). (C) Heatmap of the expression profile of the 9 m7G-related lncRNAs. (D) KM curves displayed the OS of LIHC patients between high- and low-risk groups. (E) ROC curves of the risk model of 1, 3, and 5 years for OS.
PMC9354608
fgene-13-906496-g004.jpg
0.424394
46cda5b63e074b93afa16443be83d964
Prognostic value of the 9-m7G-related-lncRNA risk model between the two groups in the testing set. (A) Distribution of the risk score (the x-axis represented the LIHC patients arranged according to the risk score, and the y-axis represented values of the risk score for each patient). (B) Scatter plot of survival status and risk score (the x-axis represented the LIHC patients arranged according to the risk score, and the y-axis represented the survival time of each patient). (C) Heatmap of the expression profile of the 9 m7G-related lncRNAs. (D) KM curves displayed the OS of LIHC patients between high- and low-risk groups. (E) ROC curves of the risk model of 1, 3, and 5 years for OS.
PMC9354608
fgene-13-906496-g005.jpg
0.463534
e4319626be124793a15ae2f543957e0b
Kaplan–Meier survival analysis stratified by age, gender, tumor grade, and stage between the high- and low-risk groups in the entire set. (A) Patients with age <65. (B) Patients with male gender. (C) Patients with tumor grade 1-2. (D) Patients with tumor stage Ⅰ–Ⅱ. (E) Patients with age ≥65. (F) Patients with female gender. (G) Patients with tumor grade 3-4. (H) Patients with tumor stage Ⅲ–Ⅳ.
PMC9354608
fgene-13-906496-g006.jpg
0.425997
07dd4b47abb144c9943b9465f38edf03
Assessment of the independent prognostic factors and construction of a prognostic nomogram in the entire LIHC set. (A) Univariate Cox regression analysis of the clinical characteristics and risk score with the OS. (B) Multivariate Cox regression analysis of the clinical characteristics and risk score with the OS. (D) Nomogram predicting the probability of 1-, 2-, and 3-year OS. (C) ROC curves of the clinical characteristics and risk score. (E) Calibration plot of the nomogram predicting the probability of the 1-, 2-, and 3-year OS.
PMC9354608
fgene-13-906496-g007.jpg
0.436801
d130eda1af894d4692757c4607b0e6be
Evaluation of the tumor immune landscape and immunotherapy response based on the m7G-related lncRNA model in the entire LIHC set. (A,B) Waterfall plot displayed top 20 mutation genes’ information in the two risk groups. (C) KM survival analysis of OS stratified by tumor mutation burden and the m7G-related lncRNA model. (G) TIDE prediction difference between two risk score subgroups. (D) Significant KEGG pathways enriched in high-risk patients. (E) Difference in tumor infiltration immune cells based on ssGSEA scores between two risk groups. (F) Difference in immune-related functions based on ssGSEA scores between two risk score subgroups. (H) Expression of immune checkpoint blockade-related genes between the two risk groups.
PMC9354608
fgene-13-906496-g008.jpg
0.44692
509b3c7ae9df43358fc54e9ffce3c306
Ten years of spherical equivalent values on the pseudophakic and fellow phakic eyes in the four groups divided by age.(A) Group I had the steepest yearly change in spherical equivalent in the pseudophakic eyes among the four age groups at -1.11 D (R2 = 0.954), followed by group II at -0.91 D (R2 = 0.979), group III at -0.42 D (R2 = 0.975), and group IV at -0.20 D (R2 = 0.674) (P < 0.001). (B) No significant difference was shown in yearly SE changes in the phakic eyes among the age groups (-0.39 D in group I; -0.52 D in group II; -0.29 D in group III; and -0.14 D in group IV, P = 0.502).
PMC9355217
pone.0272369.g001.jpg
0.459794
3260a99bf02e42569f7819200005ef79
Approved anticancer drugs in China and the USA from 2012 to 2021. Note: The vertical ordinate is the number of approved anticancer drugs. The green line represents the quantitative changes of listed drugs in China while the blue one represents the changes in the USA.
PMC9355250
fonc-12-930846-g001.jpg
0.478499
2279d67a9bf9412a9ac05e1d9374f96c
The Venn diagram and the latest progress of listed anticancer drugs in China and the USA. Note: In the upper Venn diagram, the orange circle indicates listed drugs in the USA while the blue one indicates marketed products in China. The overlapping region indicates the products listed in both countries. The horizontal bars underneath described the research progress of drugs that have not been approved in the two countries from 2012 to 2021. Out of 45 anticancer drugs only approved in China in this period, 15 were approved in the United States before 2012.
PMC9355250
fonc-12-930846-g002.jpg
0.508458
c77290ee9d6649f0b128752426cf067c
Listing time lag of anticancer drugs between China and the USA from 2012 to 2021. Note: The horizontal axis indicates the approval time of anticancer drugs in the USA, and the vertical axis indicates the approved time lag between China and the USA. Each red star represents one product approved in the two countries. The blue line shows a change tendency of the median time lag from 2012 to 2021.
PMC9355250
fonc-12-930846-g003.jpg
0.454518
76a23cc747b949b68ea84a5c01eab705
Target distribution of new cancer drugs in China and the USA from 2012 to 2021.
PMC9355250
fonc-12-930846-g004.jpg
0.466112
12a4320b2d7742f7a4114368581ee8a5
Cancer site distribution of approved new cancer drugs in China and the USA from 2012 to 2021. Note: MCC, Merkel cell carcinoma. BPDCN, blastic plasmacytoid dendritic cell neoplasm. TGCT, tenosynovial giant cell tumor.
PMC9355250
fonc-12-930846-g005.jpg
0.40425
e717b4c42536488294719fcaf8464f36
Dose-volume histograms comparison for BM structures From left to right, SOC (blue) and LS (red) dose volume histograms for the Wp-BM, Ls-BM, Il-BM and Lp-BM respectively, in both prostate and prostate bed plans. The solid line represents the median and the colored spread is the interquartile range. Abbreviations: SOC = standard-of-care, LS = lymphocyte-sparing, BM = bone marrow, Ls = lumbosacral spine, Il = ilium, Lp = low pelvis, Wp = whole pelvis.
PMC9356260
gr1.jpg
0.49732
5314eda7a99b4de387b63289828809e0
Dosimetric parameters comparisons for bone marrow volumesAbbreviations: SOC = standard-of-care, LS = lymphocyte-sparing, BM = bone marrow, Ls = lumbosacral spine, Il = ilium, Lp = low pelvis, Wp = whole pelvis.
PMC9356260
gr2.jpg
0.440584
afa536f106c1432f819740f834b353b1
The effect of nitrogen fertilizer rate on total plant dry weight in plants that were not inoculated with Fusarium oxysporum f.sp. cubense (A), disease severity in inoculated plants (B) and dry weight in inoculated plants (C). For regression model statistics see Table 1. Points have been jittered in the x dimension to avoid overplotting.
PMC9356348
fpls-13-907819-g0001.jpg
0.487778
0542a136aba64d84aa42e204ebc4a413
The effect of ammonium and nitrate fertilizer addition on the concentration of soil ammonium (A), nitrate (B), and pH (C) at the time of harvest.
PMC9356348
fpls-13-907819-g0002.jpg
0.515974
81f89f99003e4cd6a1d61d0317e4ef64
(A) The effect of nitrate and ammonium fertilizer addition on the δ15N of aboveground plant tissue, showing values for the original soil (dotted line) and fertilizer (large colored points for each fertilizer type and rate, red = ammonium, blue = nitrate). (B) δ13C of aboveground plant tissue. Points have been jittered in the x dimension to avoid overplotting.
PMC9356348
fpls-13-907819-g0003.jpg
0.469753
817e60f90d3540e59fdcd96facbf51b4
Fusarium oxysporum f.sp. cubense DNA concentration in banana rhizosphere soil in relation to nitrogen fertilizer form and (A) Internal disease severity of banana plants, (B) Nitrogen fertilizer rate, and (C) Soil pH.
PMC9356348
fpls-13-907819-g0004.jpg
0.442402
9a42a4634f5c467a9a90bafd872aff12
Bacterial alpha diversity (Shannon index) as affected by the rate and form of nitrogen fertiliser addition (A) and soil pH (B). Points in the left panel have been jittered in the x dimension to minimize overplotting.
PMC9356348
fpls-13-907819-g0005.jpg
0.442913
201748a309484c04bb15dd1b86078218
A redundancy plot of the fungal community with inoculation of Fusarium oxysporum f.sp. cubense (Y) or not (N) constrained by inoculation. Circles represent samples and crosses OTUs. The far-left cross represents the genus Fusarium, which exerts considerable influence on the significance of the treatment effect.
PMC9356348
fpls-13-907819-g0006.jpg
0.496611
868bf4d654a941ee98fe69d682a02345
Redundancy analysis of the proteomic output constrained by factors of inoculation, nitrogen form and nitrogen rate. Point colours indicates nitrogen rate and ellipses with text labels indicate combinations of inoculation (Y or N) with nitrogen form (Ammonium or Nitrate).
PMC9356348
fpls-13-907819-g0007.jpg
0.414498
8ce70a2ba60d450db2da1469ff2057bb
Log2 transformed expression rates of measured forms of pathogenesis related protein 1 (PR1), shown with gene locations, with treatments of inoculation with Fusarium oxysporum f.sp. cubense, nitrogen rate and form.
PMC9356348
fpls-13-907819-g0008.jpg
0.458846
e422fa433a394ecd9b5503854c5955d2
Risk factors for cerebral palsy [2, 7, 10].
PMC9356840
OMCL2022-2622310.001.jpg
0.379185
13e5de013929479089b197b46c781a15
Causes of cerebral palsy [2, 8, 11–13, 15].
PMC9356840
OMCL2022-2622310.002.jpg
0.452334
f1c18bdaca954ebc838b148c55addca0
Events leading to cerebral palsy [2, 8, 11–13, 15].
PMC9356840
OMCL2022-2622310.003.jpg
0.454676
5734514c566549ad967592d8542abb60
Different types of cerebral palsy [2, 14].
PMC9356840
OMCL2022-2622310.004.jpg
0.446273
2546601886094467869235b470846613
Comorbidities associated with cerebral palsy [11, 17–20].
PMC9356840
OMCL2022-2622310.005.jpg
0.490769
9e064ecbaaed4c43930928ef2e276f5b
Diagnostic criteria for detecting cerebral palsy [2, 13].
PMC9356840
OMCL2022-2622310.006.jpg
0.455419
b8ae103ee157401ab12fce62dcd6b906
Prevention and management of cerebral palsy [28, 30, 31].
PMC9356840
OMCL2022-2622310.007.jpg
0.406158
cf2a85d04d3445d0aad12d9bd4c6b5ef
Time-dependent AUC values of pN stage and LNR for the prediction of OS in the training set (a), the internal validation set (b) and the external validation set (c).
PMC9356966
10434_2022_11911_Fig1_HTML.jpg
0.463576
9c31c340e9324132a9227196673bc40e
LASSO Cox regression model construction. a LASSO coefficients of fourteen features; b Selection of tuning parameter (λ) for the LASSO model. c Nomogram for predicting 3- and 5-year OS in YBC patients.
PMC9356966
10434_2022_11911_Fig2_HTML.jpg
0.44227
2681cbc706d3422585d6d6886194f5d7
The calibration curves to predict 3- and 5-year OS in the training set (a), the internal validation set (b) and the external validation set (c). Time-dependent ROC curves comparing the use of the nomogram and AJCC TNM staging system to predict the 3- and 5- year OS for YBC patients in the training set (d,e), the internal validation set (f,g) and the external validation set (h,i), respectively.
PMC9356966
10434_2022_11911_Fig3_HTML.jpg
0.49948
a97af635483644d0b087940dc75d16e2
DCA curves of the nomogram and AJCC TNM staging system for predicting 3- and 5-year OS in the training set (a,b), the internal validation set (c,d) and the external validation set (e,f).
PMC9356966
10434_2022_11911_Fig4_HTML.jpg
0.453705
bf1a9925106641a09cad6c092357ce71
Kaplan-Meier curves of OS for risk stratification and defferent AJCC stages in the training set (a,b), the internal validation set (c,b) and the external validation set (e,f).
PMC9356966
10434_2022_11911_Fig5_HTML.jpg
0.422587
37b1ee054f854d74b23ecce7db158034
Resveratrol chemical structures (trans and cis forms) and its biological activities and toxic side effects. (A) Trans-resveratrol. (B) Cis-resveratrol. (C) Biological activities and toxic side effects of resveratrol.
PMC9357872
fphar-13-921003-g001.jpg
0.442006
0a7c8d0575024d59be8fccf00726d74e
Potential mechanisms of resveratrol in relieving knee osteoarthritis. There are many molecular mechanisms involved in the occurrence and development of knee osteoarthritis. Resveratrol plays multiple positive roles in knee osteoarthritis, reducing inflammatory activation, cell apoptosis, maintaining cartilage homeostasis and promoting autophagy through several signal pathways. (A) Anti-inflammatory effects. (B) Anti-apoptotic/proliferous effects. (C) Anti-catabolic/Pro-anabolic effects. (D) Autophagy-promoting effects. ↑: up-regulation. ↓: down-regulation.
PMC9357872
fphar-13-921003-g002.jpg
0.449354
642762ed3a2a432e868b7fca8b43a69a
The new application of resveratrol in knee osteoarthritis. The schematic diagram illustrates the current clinical method of combining resveratrol with cartilage tissue engineering to treat knee osteoarthritis.
PMC9357872
fphar-13-921003-g003.jpg
0.509981
a16d4ddafe2348148d6e3a5ad39548f6
Trait greed and the difference between mixed and gain only pumping behavior for not exploded balloons (A) or all balloons (B). Note: Y-axis intercept = difference in average number of inflations of unexploded balloons (mixed - gain only BART) as criterion; X-axis intercept = trait greed as predictor. The shaded areas depict SEM
PMC9358376
12144_2022_3553_Fig1_HTML.jpg
0.456749
70ba7ab02cc74c31950b449c3c9c785a
Trait greed and the inflation behavior on unexploded balloons (gain only & mixed BART) (A & B) and all balloons (gain only & mixed BART) (C & D) as criterion. Note: The shaded areas depict SEM
PMC9358376
12144_2022_3553_Fig2_HTML.jpg
0.444595
2c75c9f0645b439ab50c1d6c41dca924
Cross-kingdom networks and bacteria-only networks in wild and domesticated rice seed microbiomes. (A,B) Bacteria-only co-occurrence network of wild and domesticated rice seed microbiomes. (C,D) Cross-kingdom (bacterial-fungal) co-occurrence network of wild and domesticated rice-seed microbiomes. Orange nodes are bacterial nodes. Purple nodes are fungal nodes. The size of the node is proportionate to betweenness centrality. Blue edges are co-occurrence network edges with positive correlation coefficients. Red edges are co-occurrence network edges with negative correlation coefficients. (E) Change of betweenness centrality of the same bacterial nodes in the bacteria-only network (x-axis) and bacterial-fungal network (y-axis). (F) Change in eigenvector centrality of the same bacterial nodes from a bacteria-only network (x-axis) to a bacterial-fungal network (y-axis). The dashed line is y = x. Solid lines (red and blue) are regression curves using locally weighted smoothing (loess) to wild and domesticated nodes, respectively. The grey area next to the regression curves indicates a 95% CI.
PMC9358436
fmicb-13-953300-g001.jpg
0.476354
2520b000203c43598f221d3d02e0cdeb
Robustness analysis and connectance, transitivity, modularity, and nestedness of cross-kingdom and bacteria-only networks in wild and domesticated rice seed microbiomes. (A) Robustness analysis by in silico extinction experiments. Nodes were deleted from the network in order of degree, betweenness centrality, and eigenvector centrality, and randomly. The size of the largest component (y-axis) was recorded after every extinction event until all vertices were removed. For robustness curves, the fraction of nodes extinct and the fraction of the largest component size (largest component size after the attack ÷ largest component size before any extinction) were plotted on the x- and y-axes, respectively. (B) Area under the robustness curves for each attack order and network. (C) Z-score normalized connectance, transitivity, and modularity. Z-score normalization of summary statistics was carried out using the mean and SD of random configuration models (with the curveball method). Because the connectance of the random model had a standard deviation of 0, Z-score normalization was done by dividing by the mean of the random model. (D,E) Visualization of nestedness in wild and domesticated cross-kingdom co-occurrence networks. Rows are bacterial species and columns are fungal species. A red pixel denotes a link between bacterial and fungal species. Only edges connecting bacterial and fungal species were used to create the bipartite network.
PMC9358436
fmicb-13-953300-g002.jpg
0.476853
3a1cd0ed754d4b5fbc2f90ca8a2d687a
Ecological interpretations of cross-kingdom co-occurrence networks. (Top) Cartoon illustrating ways to interpret individual negative and positive fungal-bacterial edges. Negative interactions include competition and predator–prey relationships, whereas positive interactions are cooperative, such as coexistence, facilitation, and mutualism. All positive and negative correlations are not cooperation and competition, respectively. (Middle) Dynamical modeling of co-occurrence networks using generalized Lotka-Volterra (gLV) and consumer-resource models. The cartoon depicts species dynamics related to the gLV and consumer-resource model, respectively (only for illustration purposes). These models can be used to supplement the network to elucidate the mechanism of the interactions. (Bottom) Effects of abiotic and biotic factors on cross-kingdom networks. To investigate cross-kingdom interactions in natural microbial communities, it is important to treat microbial interactions as variables dependent on the magnitude of stress, space, time (abiotic factors), and host (biotic factor). (Left) Stress gradient hypothesis—the relative importance of competitive vs. facilitative interactions varies along the environmental harshness gradient. Another consideration is the host effect (biotic factor). (Right) The host immune system mediates the interaction between the bacterial and fungal communities. The biotic factors influencing the microbial community can be affected by host plant pathogen susceptibility or resistance.
PMC9358436
fmicb-13-953300-g003.jpg
0.456987
70ab02ecc26d4a52bb70e5099a87d615
Incidence of CAPA in low, median, and high groups, designated by tertiles of mean daily dose of dexamethasone, which were measured from admission to CAPA diagnosis in CAPA group, and measured from admission to ICU discharge or death in non-CAPA group. (low: 0–3.48 mg/day, median: 3.48–7.21 mg/day, high: >7.21 mg/day)
PMC9359693
figs1_lrg.jpg
0.489332
04a0c7d894d24ef8a87f83fd1be9de73
Study flowchart. CAPA, COVID-19-associated pulmonary aspergillosis; ICU, intensive care unit; qPCR, quantitative polymerase chain reaction; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
PMC9359693
gr1_lrg.jpg
0.394152
dbc48c6ae1e0468486a2060bc24aefa0
Kaplan–Meier curves of (a) all patients (n = 72) (log-rank p = 0.024) and (b) the mechanically ventilated patients (log-rank p = 0.065) with and without CAPA. CAPA, COVID-19-associated pulmonary aspergillosis; ICU, intensive care unit.
PMC9359693
gr2_lrg.jpg
0.406812
12f35649e5414007910f0a9040109d6f
SARS-CoV-2 viral shedding time between the patients with and without CAPA. (a) The distribution of the SARS-CoV-2 viral shedding time is presented in dot plots (Mann–Whitney U test, p = 0.037). (b) Kaplan–Meier curves (log-rank p = 0.022). CAPA, COVID-19-associated pulmonary aspergillosis; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
PMC9359693
gr3_lrg.jpg
0.436477
3ef7080979fc4156b607ae0adea23507
Results for performance measures against the third set of scenarios (Scenarios 23 to 33).
PMC9359798
gr10_lrg.jpg
0.513335
4868e6b8c2d348b99ed347c48da027c4
EKMIH framework for NEPT.
PMC9359798
gr1_lrg.jpg
0.425678
7c572c4bf35b4af6bc652018e199f0ca
Pick-up locations and hospitals/clinics for patients.
PMC9359798
gr2_lrg.jpg
0.407431
612b74188bd74659a7f48707dbc1c8ca
WC and ERC for the SKMH framework.
PMC9359798
gr3_lrg.jpg
0.396589
690b3cf4c4c3479580098493274d199b
WC and ERC for the EKMIH framework.
PMC9359798
gr4_lrg.jpg
0.452151
8eb9acafe91448839b87c5c658883bb3
Impact of increase in maximum cluster size on the cost for instance B4.
PMC9359798
gr5_lrg.jpg
0.473843
577c1cdc4b6f4f0b8628a9fffb9aac5e
Impact of increase in maximum cluster size on the cost for instance C4.
PMC9359798
gr6_lrg.jpg
0.388278
1097b327a21e488cbfa04a2c780208a5
Impact of value of K on the cost.
PMC9359798
gr7_lrg.jpg
0.477105
1011b7df838445e3b5d7323c6a119665
Results for performance measures against the first set of scenarios (Scenarios 1 to 11).
PMC9359798
gr8_lrg.jpg
0.445079
a7918d8d2dae4f028253ce080d29cebc
Results for performance measures against the second set of scenarios (Scenarios 12 to 22).
PMC9359798
gr9_lrg.jpg
0.528809
8f9ff2720e8544b68a858f96d0204a7d
Evolution of the PFC I-PASS SCORE Program. Abbreviations: PFC, patient and family-centered; PFCRs, patient and family-centered rounds; SCORE, safer communication on rounds every time.
PMC9360201
mep_2374-8265.11267-g001.jpg
0.46783
c3601dd7832444bbbb98b274a1b86541
Patient and Family-Centered I-PASS Rounds: Do Every Time Process. Abbreviation: ACP, advanced care provider.
PMC9360201
mep_2374-8265.11267-g002.jpg
0.386009
1ffcdec8a08948ff8267b846b76f7cd9
9 year-old girl with right subtrochanteric fracture treated with triple ESINs. (A) AP view of femur before surgery. (B) AP view of femur after surgery. (C) Lateral view of femur after surgery. (D) AP view of femur at 6th month follow-up. (E) Lateral view of femur at 6th month follow-up. (F) AP view of femur after implant removal.
PMC9360405
fped-10-894262-g001.jpg
0.448615
7689f9426def41eabab7b7ed41eeb45c
10 year-old girl with right subtrochanteric fracture treated with locking plate. (A) AP view of femur before surgery. (B) AP view of femur after surgery. (C) Lateral view of femur after surgery. (D) AP view of femur at 6th month follow-up. (E) AP view of femur after implant removal. (F) Lateral view of femur after implant removal.
PMC9360405
fped-10-894262-g002.jpg
0.412695
457bc5440eb646789b7b05b63568774f
MRI T2/FLAIR images showing periventricular white matter hyperintensity along with hyperintensities in basal ganglia and thalamus
PMC9363804
ijccm-26-961-g001.jpg
0.413112
174004f9f26d45339fadee07e32ec4a6
Distribution ranges of five Takydromus lizard species and the locations of the populations sampled for behavioural, physiological and life-history responses to climate warming. Different colours in outlines indicate different species in the map and species photographs. (Online version in colour.)
PMC9363995
rspb20221074f01.jpg
0.444565
c933a5221dbc4f6794f3aae1d6ee005a
TSM for five grass lizard (Takydromus) species across latitudes. Red, blue and green spots indicate the TSM under current, 2050 and 2070 situations. The species are listed from temperate to tropical areas on the x-axis. Error bars represent s.d. Because of the same trends of future climate, we only show the results of the RCP 4.5 emission scenario in the text. (Online version in colour.)
PMC9363995
rspb20221074f02.jpg
0.416513
57fa1584ec4f4ca2a84b0c5116ae0dde
Fitness-related traits for five grass lizard (Takydromus) species across latitudes in the current climate (red dots), and predictions for 2050 (blue dots) and 2070 (green dots). (a) Activity time, (b) metabolic rate, (c) water loss, (d) incubation period and (e) time window for successful embryonic development. Error bars represent s.d. Because of the same trends of future climates, we only show the RCP 4.5 emission scenario results in the text. (Online version in colour.)
PMC9363995
rspb20221074f03.jpg
0.476277
2544e0f4da9e417c826378001caa7ba3
Spatial distribution and habitat suitability of five grass lizard (Takydromus) species in the current climate, and predictions for 2050 and 2070. The first two columns indicate the species distribution in China derived from spatial distribution maps (indicated by [70]). The third and fourth columns indicate the habitat suitability in 2050 and 2070 under climate warming from Hybrid-SDMs for each species. The colour indicates the suitability. The list of species on the y-axis indicates the latitudinal areas of the species. Because of the same trends of future climate, we only show the RCP 4.5 emission scenario results in text. (Online version in colour.)
PMC9363995
rspb20221074f04.jpg
0.423261
8a9ff4c682644733ba2f35567a15dd17
Change of habitat suitability (a) and per cent area (b) for five grass lizard (Takydromus) species across latitudes under current and 2050 and 2070 climate warming. Blue and green spots (a) and bars (b) indicate the traits of 2050 and 2070, respectively. Error bars in (a) represent s.d. Because of the same trends of future climate, we only show the RCP 4.5 emission scenario results in the text. (Online version in colour.)
PMC9363995
rspb20221074f05.jpg