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0.473271 | 40a44f15f24440489180089157c2fd0e | Classification performance of AI-bRNN in different brain regions and cell types.a Schematic drawing of the cerebellar Bergmann glia and the imaging timeline before and after capsaicin or vehicle injection. b Estimated pain values of capsaicin-injected animals. The estimated pain values were based on the Ca2+ activity of Bergmann glial cells in the cerebellum of the capsaicin group (n = 7 mice) and the saline group (n = 14 mice). The data from the baseline non-pain condition (before the capsaicin injection) were pooled with the data from the saline-injected animals. c The classification performance for the capsaicin-induced pain condition based on the cerebellum Bergmann glia signals. Scatter plots indicate individual data. Bars indicate the mean ± SEM; *P < 0.05 compared to the matched control group (Mann–Whitney U test). | PMC9385425 | 12276_2022_828_Fig3_HTML.jpg |
0.4335 | 4c218af168464835835b22820bbf9ef8 | AI-bRNN can classify another somatosensation, itch.a A schematic drawing of the Ca2+ imaging schedule for S1 neurons in the chloroquine-induced itch conditions. b, c Estimated itch values of the chloroquine-injected animals based on the Ca2+ activity of S1 neurons. The data from the baseline non-itch condition (before chloroquine injection) were pooled with the data from the saline-injected animals. Saline (10 μl, s.c.) group (n = 24 mice); chloroquine (100 μg/10 μl, s.c.) group (n = 10 mice); formalin (5%, s.c.) group (n = 11 mice) d The classification performance for chloroquine-induced itch conditions based on the S1 neurons. Points on the scatter plots indicate individual data. Bars indicate the mean ± SEM; ***P < 0.001, **P < 0.01 compared to the matched control group (Mann–Whitney U test). | PMC9385425 | 12276_2022_828_Fig4_HTML.jpg |
0.456214 | b931e4bf2aef4ae68ab9643e645c860a | Wearable adjunct ozone and topical antibiotic therapy system. (a) Ozone and antibiotic adjunct therapy can be used as an alternative treatment for skin and soft tissue infections that do not respond to traditional therapies. Ozone provides antimicrobial properties and enables antibiotic to enter cell and disrupt cell functions, such as protein production. (b)The system utilizes gaseous ozone and gas permeable and drug-eluting nanofiber mat for treating developing wounds in the following process: (i) All-in-one wound patch with drug-eluting nanofiber mesh and gas permeable membrane is applied to skin wound. (ii) NFs begin to dissolve and release the topical antibiotics. (iii) Ozone is applied to the system for full treatment duration as topical antibiotics are completely released from NFs. Ozone and antibiotics work together to eliminate infection. (iv) Once the wound has healed, the wound patch is removed from the area. Combination of ozone and antibiotic treatment can treat antibiotic resistance infections and prevent development of new infections, leading to faster healing times. | PMC9385669 | 41598_2022_17495_Fig1_HTML.jpg |
0.488396 | 84b39e85237b4c5b8beaff067528d443 | Portable adjunct ozone and topical antibiotic therapy system. (a) Ozone wound treatment system designed to administer adjunct ozone and antibiotic therapy topically to dermal wounds. System comprised of portable ozone generation system with microblower for ozone delivery and a porous mesh of drug-eluting PVA nanofibers for antibiotic delivery. Portable rechargeable system is fitted to custom housing and utilizes onboard low-power electronics for. (b) Relationship of concentration of ozone created by portable system to the mass generation rate. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig2_HTML.jpg |
0.405325 | 40806924171244a8881f7c42ceeb284e | Properties of electrospun NF mat. Microscope image of (a,e) ozone delivery patch surface and (b,f) after coating with linezolid containing NFs, (c,g) and after coating with vancomycin containing NFs, (d,h) after the dissolution of the NFs. Images were taken using optical microscope (a–d) and SEM (e–h). (i) Histogram displaying frequency of pore size within vancomycin and linezolid spun fiber mats. (j) Contact angle measurement of dressing at various stages of treatment. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig3_HTML.jpg |
0.455451 | 90441e5d3e534080967cbb9b6adaa804 | Porosity characterization of ozone dressing with and without drug eluting NFs coating. (a) Internal flow resistance at varying flowrates for dressing at different stages of application. (b) Comparison of internal flow resistance at 25 mL/min. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig4_HTML.jpg |
0.475852 | bac9200771644bbc9fcad261ccb8355f | Dissolution characterization of drug eluting NFs. (a) Dissolution rate of NF fabricated with partially hydrolyzed and fully hydrolyzed PVA. (b) Dissolution over time of partially hydrolyzed NFs infused with drug mimicking dies (Red for vancomycin and Blue for linezolid). (c) Proportion of material dissolved by critical time of 10 min (< 3% total treatment duration) for NFs in liquid and gel media. (d) Comparison of time needed to achieve critical dissolution of blue dye (linezolid) NFs in buffer solution with different pH levels. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig5_HTML.jpg |
0.427614 | 03a1a36fa4774f8c8f56229626479caf | Antimicrobial efficacy and cell viability under continuous exposure to differing levels of ozone (2–8 mg/h). Antimicrobial effect against (a) P. aeruginosa and (b) E. coli bacteria cultures in PBS over the course of 8 h. (c) Cell viability of human fibroblasts treated with 6 h of ozone at 2–8 mg/h at 37 °C. Viability was measured 1 day, 3 days, and 7 days after treatment ended. (d) Live/Dead staining of human fibroblast cells exposed to varying levels of ozone therapy 1 day and 7 days after treatment. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig6_HTML.jpg |
0.404199 | eddc3495c4b841ea8ed77a0275b1044b | Antibacterial efficacy against bacteria cultures in TSB media and cell viability results of adjunct ozone and antibiotic therapy test in vitro at 37 °C. (a) Results for ozone + linezolid and ozone + vancomycin adjunct therapy on P. aeruginosa. (b) Antibacterial results of ozone + linezolid and ozone + vancomycin adjunct therapy on E. coli. Ozone was applied at 4 mg/h for 6 h. Linezolid and vancomycin were applied in solution at 200 μg/mL. (c) Viability of human fibroblast cells exposed to 6 h of ozone, ozone + vancomycin, and ozone + linezolid treatment measured 1 day, 3 days and 7 days after treatment ended. (d) Live/Dead staining of human fibroblasts 1 day and 7 days after treatment ended. Error bars denote standard deviation. | PMC9385669 | 41598_2022_17495_Fig7_HTML.jpg |
0.436997 | 35694d0a5eae44d3919c361b1e694cdb | Different stages of developing Be my Voice application. | PMC9386513 | fpsyt-13-954602-g0001.jpg |
0.401677 | 23871f0029a94810a70c32cf59ffc6bd | Vaginal atresia in case of Mayer-Rokitansky-Kuster-Hauser syndrome. Transrectal exam reveals complete vaginal absence. Megalourethra is a consequence of urethral coitus. | PMC9386626 | gr1.jpg |
0.438636 | 7bec95379dca4b2bba3c4c3b3c8dfdb9 | a) Design of introital flaps; b) Anastomosis of the flaps with the neovagina to create wide introitus. | PMC9386626 | gr2.jpg |
0.414013 | 4a5dbb794c7f490f95460632ec58a032 | a) Dilated urethral orifice with duplicated vagina due to longitudinal vaginal septum; b) Longitudinal septum separated vaginal cavity in two parts with stenotic introitus; c) Resection of the vaginal septum enables joining of two separated parts of the vagina; d) Normal vaginal cavity is achieved at the end of resection and reconstruction. | PMC9386626 | gr3.jpg |
0.399101 | 6dabb224cab4494c8fdfc6f3f7575baf | APIM Associations between Sexual Arousal, Relationship Quality and Sexual Satisfaction. Note: Solid lines depict actor effects. Dotted lines depict partner effects. An * denotes significant effects (P < .05). The percentages represent the variance explained in each outcome variable. For ease of interpretation, residual terms and correlations between IVs and between DVs are not included in the figure. | PMC9386639 | gr1.jpg |
0.448707 | 4e2f815619204c769484574199484665 | A flow diagram depicting prospective participants and respondents to the RESPPONSE study, August 2020 - March 2021. | PMC9387116 | gr1.jpg |
0.426201 | b148295747bd48f1936070e56e57fa82 | Plot depicting the number of surveys returned over the study time (upper plot) and the significant non-linear relationship of average intention to receive COVID-19 vaccine and time, with shaded area indicating the 95 % CI around the estimates of vaccine intentions. The dashed vertical line indicates Nov 17th, 2020, which signifies the time around which the information regarding development and approval of the mRNA vaccines was released in Canada. | PMC9387116 | gr2.jpg |
0.497501 | ea6768067d304f9c92e1235edc8c15bd | Plot depicting the change in COVID-19 vaccine intention (%) pre-and post-Nov 17, 2020, by retrospective categorization of reported perceived value of vaccines, stratified by seasonal influenza (flu) vaccine intentions. Error bars indicate 95 % CI. | PMC9387116 | gr3.jpg |
0.438055 | 5c827c6ec2ad42d8b9d6582fd8a55860 | 2D structures of top four selected phytochemicals along with the reference drug. | PMC9387841 | pone.0269739.g001.jpg |
0.432406 | 5da013240f4b45a295e8a80c063e1b71 | Docked scutellarin & Gentiopicroside/Endothlien-1 with ET-1; side chains atoms of Asn 158, Lys 161, Lys 97 making hydrogen bonds.Docked poses of compound highlighting the most active residues of protein’s binding pocket as shown above. | PMC9387841 | pone.0269739.g002.jpg |
0.507341 | f491e3a3be834c38bed03b95630736fe | Docked Citicoline & Oxalyldiaminopropionic acid with ET-1; side chains atoms of Lys161, Lys97 making hydrogen bonds.Docked pose of compounds highlighting the most active residues of protein’s binding pocket is shown above. | PMC9387841 | pone.0269739.g003.jpg |
0.391251 | eb90f91190be4114be30a277b0a55a55 | Reference drug docking complex along interacting residues. | PMC9387841 | pone.0269739.g004.jpg |
0.414715 | b1fb450fd8884ee49f4c1e2d2bdfc052 | Detail representation of root mean square deviation plots of protein ligand complex. | PMC9387841 | pone.0269739.g005.jpg |
0.436123 | 998ec6f6e93b44cea1e04bedf75f869d | Root mean square fluctuation of docked complexes plots over 100ns. | PMC9387841 | pone.0269739.g006.jpg |
0.372131 | fd56f81a0d3b4e57b251eb5b2496fab2 | The SASA plots of docked complexes over 100 ns MD simulation and the time frame evolution of 100ns against the radius of gyration (Rg) (E & F) (G & H). | PMC9387841 | pone.0269739.g007.jpg |
0.41975 | 7e9d416a7a704b17a980eee3b0179e0c | During 100-ns MD simulation, Endothlien-1 interacts with the compounds as a protein-ligand complex. | PMC9387841 | pone.0269739.g008.jpg |
0.476902 | 8ac034b862c34f01917ad885d9a51205 | Risk of bias summary. | PMC9388284 | CMMI2022-3739463.001.jpg |
0.43874 | 21b1ebde400143438ec3447eb2e81891 | Risk of bias graph. | PMC9388284 | CMMI2022-3739463.002.jpg |
0.464289 | 388995ad34fd4e5e88fe9d040c24f2bc | Search strategy and final included and excluded studies. | PMC9388284 | CMMI2022-3739463.003.jpg |
0.456782 | 0b29860753e941c2bb9c53093d3d23fd | Funnel plot of all-cause mortality. | PMC9388284 | CMMI2022-3739463.004.jpg |
0.452363 | 71651ee995134a6885b5323d0fc8e1a7 | Funnel plot of stroke. | PMC9388284 | CMMI2022-3739463.005.jpg |
0.414032 | a76bb81eb8ee41aaac6358299c721612 | Funnel plot of major cardiovascular events. | PMC9388284 | CMMI2022-3739463.006.jpg |
0.438501 | e76de940929a42569924033b7b85129b | Schematics of the steady state method for T2 and RF field estimation—its design and verification. Starting from simulations, through assessment of the estimation algorithm, via a 3D head-shaped brain-like phantom, to human imaging. Left—a design of a steady-state configuration based on Bloch simulations that provides θ(T2,α) for specific φinc, which was thereafter utilized to generate T2 and α in the 2D space (θ1, θ2). The new space allows to extract T2 and α from θ1 and θ2. Center—the estimation algorithm was assessed via simulations and brain-like phantom measurements. In these measurements, a realistic signal \documentclass[12pt]{minimal}
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\begin{document}$$\angle S$$\end{document}∠S, from which the T2 and α (or B1 distribution) were estimated. Right—human imaging at 7 T MRI provided high-resolution whole-brain T2 maps, while coping with the B1 distribution. | PMC9388657 | 41598_2022_17607_Fig1_HTML.jpg |
0.449029 | da7a8af854854723a3125dc37fd6f72d | The phase of the steady-state signal as a function of T2 and the flip angle. (a) θ(T2, α, T1) dependence (Bloch simulation results) for a representative small φinc (φinc = 2°). The dependence on T2, α, and T1 is shown in 1D plots and in 2D. (b) T2 and α distributions in the new (θ1, θ2) 2D space. Two examples are shown: Top—(φinc1 = 2°, αscan1) with (φinc2 = 2°, αscan2 = 2αscan1). Bottom—(φinc1 = 3°, αscan1) with (φinc2 = 1.5°, αscan2 = 2αscan1). In each case, α (θ1, θ2) and T2 (θ1, θ2) are shown with the equi-T2 and equi-α lines. | PMC9388657 | 41598_2022_17607_Fig2_HTML.jpg |
0.401015 | 6e019de3063d43639ae22bec02d4b927 | Assessment of estimation bias and variability in phantoms. (a) Comparison of the T2 obtained with the phase-based method and SE–SE in agar tubes. Top—a central slice of the T2 maps and magnitude images. Bottom—estimated T2 for each tube as a function of T2 with SE–SE; aslope = 1.01, relative deviation error = 0.5%. The average standard deviation was 0.5 ms for the phase-based method, and 0.7 ms for SE–SE. (b–d) Comparisons using a 3D-head-shaped brain-like phantom. (b) T2 and α maps estimated by the phase-based method. (c) T2 map estimated with SE–SE. And (d) α map estimated using the vendor’s RF field mapping scan. Two main cross-sections are shown for all cases, Sagittal and Axial. For comparison, the average T2 and standard deviation was calculated in the same region of interest (marked by a blue contour for the phase-based method and a red contour for SE–SE). The average deviation between the α maps of the phase-based method and of the vendor’s RF mapping was calculated to be 0.56° for the Sagittal plane and 0.84° for the Axial plane. | PMC9388657 | 41598_2022_17607_Fig3_HTML.jpg |
0.424548 | fae0e80ff758444d997edf95a2ef2495 | Comparison of T2 maps extracted with (a) 4-scans, (b) single pair with (φinc1, αscan1) and (c) single pair with (φinc2, αscan2). (d) For each case a plot for a line shown in the Sagittal and Axial scans. The images show 3D-head shaped phantom (left) and human imaging (right). The human axial plane image in (a) shows the regions that were examined and summarized in Table 1. | PMC9388657 | 41598_2022_17607_Fig4_HTML.jpg |
0.408611 | 488c85e9b6234634866685fce2f8b07d | Human imaging—T2 from the phase-based method or SE–SE, and α from the phase-based method or the vendor’s scan. (a) SE–SE Sagittal magnitude image at TE = 30 ms and the estimated T2 maps in three main cross-sections. (b) An α map using the vendor’s pulse sequence. (c) Sagittal magnitude image with φinc = 3 and α = 15°, as well as the estimated T2 and α maps in three main cross-sections. α map shown here was smoothed by a 3 × 3 filter to reduce the effect of local CSF signal. Orange arrows point to the cerebellum and brainstem regions suffering from low flip angles due to B1 inhomogeneity; their inner structure is much more pronounced—and clearly visible—in the phase-based T2 images. Purple arrows point to a region in the CSF that resulted in a low magnitude signal. | PMC9388657 | 41598_2022_17607_Fig5_HTML.jpg |
0.484268 | 031683a4747143c2bb996466ad7e4fab | Comparison of T2 estimation between the phase-based method and SE–SE. The plot shows the ratio T2 phase-based-method/T2 SE–SE per volunteer, both for WM and for GM. The error bars depict the relative deviation error [see Eq. (1)]. | PMC9388657 | 41598_2022_17607_Fig6_HTML.jpg |
0.422052 | 90a4d54436e94fe0956bea073673d89e | Human whole-brain T2 maps with a 0.85 mm isotropic voxel. (a) without denoising, (b) with denoising, based on DnCNN model for Gaussian noise removal. Arrows point to the cerebellum region, which especially benefits from denoising. Top row, Sagittal and Coronal planes. Bottom two rows, six slices of the Axial plane, at 10 mm intervals. | PMC9388657 | 41598_2022_17607_Fig7_HTML.jpg |
0.537058 | c3c015c190434a958554c245e21c849a | Graph showing recurrence-free survival of different surgical methods. | PMC9389190 | gr1.jpg |
0.461532 | 08556904d5554db9abaf2b87ee9f3f71 | Graph showing risk function of recurrence from different surgical methods. | PMC9389190 | gr2.jpg |
0.418478 | f1fa6713b84a4d55acb7b38ae962857f | The time-dependent ROC curve analysis with 1 year. | PMC9389190 | gr3.jpg |
0.485297 | 73ed56d27d18405aa72ba62f94b9f36e | Graphical demonstration of the preparation of a cut-off syringeLeft: cutting the tip of the 1cc syringe to allow the proper intake of a sediment plug (the red line indicates where to make the cut); right: the finished look of the cut-off syringe. | PMC9389416 | gr1.jpg |
0.487164 | 6b1cb2971c40400db16ad7e894063d9f | The stratified zonation of topmost sediment inhabited by cable bacteria | PMC9389416 | gr2.jpg |
0.419459 | de15c203025943bda6bb13c19ea42fb3 | Light microscope images of the cable bacteria filaments enriched in autoclaved intertidal sediments originally collected from Yaquina Bay, OR | PMC9389416 | gr3.jpg |
0.465251 | 86e46f65b8b4445e816c2c0ff71b8e3e | Images of the enriched cable bacteria filaments captured by a scanning electron microscope (Helios 650 Ultra Resolution Dual Beam)Left: a bundle of the extracted filaments; right: tangled cable bacteria filaments within the bundle exhibiting the typical morphological features (indicated on the topmost filament, yellow arrows: the longitudinal ridges, and red arrows: the cartwheel-like cell-cell junctions). | PMC9389416 | gr4.jpg |
0.430983 | c7a43f293f58439fa3f5f229ff2d9280 | Graphical presentation of patient position variation during the Endoscopic full-thickness resection. | PMC9389534 | fonc-12-985257-g001.jpg |
0.400873 | 6b08b19cb2924f01861898474d0f8b1e | Orbital MRI showed local edema of the right optic nerve. | PMC9389570 | omac086f1.jpg |
0.413834 | a2492fe30477455bbed29c667f70f6cc | Intracranial MRA showed the right cavernous sinus’s blood vessels were thickened and confusion. | PMC9389570 | omac086f2.jpg |
0.417158 | d41856c27d6046f99c29d464bc7bc0a9 | Selective right internal carotid arteriogram (positive view) showed a small fistula between dural CCF and peritoneal pituitary artery, and the sinus drainage was through the lower sinus rock. | PMC9389570 | omac086f3.jpg |
0.459134 | 27f38b8f079c435b80900b5e6f4e1f04 | Bilateral cavernous sinus was visualized in the middle arterial period. | PMC9389570 | omac086f4.jpg |
0.442108 | afbdd30e7e2a4dacb380bf08921637ec | Chest X-ray demonstrating bullae in bilateral upper lobes | PMC9390301 | LI-39-374-g001.jpg |
0.413054 | 25449dc9ab9f44509da0979b82294924 | CT scan demonstrating giant bullae with compression of the lung parenchyma | PMC9390301 | LI-39-374-g002.jpg |
0.532148 | 676a9e129455489a86eae0b97ac11a76 | Conceptual framework of the mediation models for the present study.Indirect effect = ab, direct effect = c, total effect = ab + c. | PMC9390893 | pone.0273329.g001.jpg |
0.469397 | 73b05bdf86ec477e9056ea9452e3412b | Flow chart (RK, remifentanil–ketamine; PK, propofol–ketamine; min, minute). | PMC9391731 | gr1.jpg |
0.49841 | 1e2c4a2bdb56477385d100cee730ce97 | SBP during the procedure. For both study groups, changes to SBP during the procedure were found to be statistically significant (p = 0.01 for SBP; repeated measurement analysis). RK, remifentanil–ketamine; PK, propofol–ketamine; min, minute. | PMC9391731 | gr2.jpg |
0.483246 | 30e9e4d7bc0f4c509ba332f6d06815d8 | DBP during the procedure. For both study groups, changes to DBP during the procedure were found to be statistically significant (p = 0.006 for DBP; repeated measurement analysis). RK, remifentanil–ketamine; PK, propofol–ketamine; min, minute. | PMC9391731 | gr3.jpg |
0.424799 | 239839996b104ae18b425db07b2a5799 | HR during the procedure. For both study groups, changes to HR during the procedure were found to be statistically significant (p = 0.027, repeated measurement analysis). RK, remifentanil–ketamine; PK, propofol–ketamine; min, minute. | PMC9391731 | gr4.jpg |
0.399184 | ec97232fb78d4ba1889c56be8ffc8dab | Monetary Incentive Delay Task used in the Adolescent Brain and Cognitive Development (ABCD) Study (53). Adapted from Knutson et al. (50). | PMC9393480 | fpsyt-13-886848-g001.jpg |
0.501804 | 4bd54dc07d31402aa4f3b538fbfcd063 | Depiction of location of ROIs used in analyzes including bilateral pars opercularis (red), pars triangularis (green), pars orbitalis (yellow), and nucleus accumbens (aqua). | PMC9393480 | fpsyt-13-886848-g002.jpg |
0.411616 | 6517ead2f1954453b93348708558eacf | Data cleaning steps for Hypothesis 1 resulting in a subsample of n = 7409. | PMC9393480 | fpsyt-13-886848-g003.jpg |
0.437711 | 955aae9a148c4b138bd931b292fee632 | Support Vector Machine (SVM) results for Hypothesis 1. (A) Graph depicting accuracy vs. cost for model selection. (B) Receiver Operating Characteristic (ROC) Curve. (C) Importance scores for each feature. | PMC9393480 | fpsyt-13-886848-g004.jpg |
0.423805 | 1210024bec954df1b9db61ae7ee56c77 | Support Vector Machine (SVM) results for Hypothesis 3. (A) Graph depicting accuracy vs. cost for model selection. (B) Receiver Operating Characteristic (ROC) Curve. (C) Importance scores for each feature. | PMC9393480 | fpsyt-13-886848-g005.jpg |
0.418592 | 314bf3eb00d147669f886befdca1dfd2 | a and b-diversity indices of the microbiota in breast milk samples from the control group (B-Con, n = 9), CXM-treated group (B-CXM, n = 13), and CXM + CFX-treated group (B-CXM + CFX, n = 3). A Observed OTUs of the microbiota in breast milk samples; B cloud plot of the Chao1 estimator regarding the microbial community richness in breast milk samples; C cloud plot of the Shannon index regarding the microbial community diversity in breast milk samples; D multiple samples PCoA analysis regarding the difference in the microbial community composition in breast milk samples. Red circles represent samples of the B-Con group; purple squares represent samples of the B-CXM group; green triangles represent samples of the B-CXM + CFX group. Each box plot represents the median, interquartile range, minimum, and maximum values. *The data are statistically significantly different from the B-Con group (p < 0.05) | PMC9395442 | 431_2022_4516_Fig1_HTML.jpg |
0.408002 | c3dd9c3bbc8c4ad790119525f4a5d1bc | Comparison of the microbiota in breast milk samples from the B-Con group (n = 9), B-CXM group (n = 13), and B-CXM + CFX group (n = 3). A and B Microbial community bar plot of the microbiota in breast milk samples at the phylum and genus levels; C and D Kruskal–Wallis rank-sum test of the microbiota abundance in breast milk samples at the phylum and genus levels; E LEfSe analysis cladogram of distinct bacteria in breast milk samples at the phylum level; F LDA score of distinct bacteria in breast milk samples at the genus level; G microbial community heatmap regarding the microbiota abundance in breast milk samples. Red cells indicate increased; blue cells indicate decreased | PMC9395442 | 431_2022_4516_Fig2_HTML.jpg |
0.448789 | f068747616a04787be2542a14baf661e | a and b-diversity indices of the gut microbiota in fecal samples from the control group (F-Con, n = 9), CXM-treated group (F-CXM, n = 13), and CXM + CFX-treated group (F-CXM + CFX, n = 3). A Observed OTUs in the gut microbiota in fecal samples; B cloud plot of the Chao1 estimator regarding the gut microbial community richness in fecal samples; C cloud plot of the Shannon index regarding the gut microbial community diversity in fecal samples; D multiple-samples PCoA analysis regarding the difference in the microbial community composition in fecal samples. Red circles represent samples of the F-Con group; purple squares represent samples of the F-CXM group; green triangles represent samples of the F-CXM + CFX group. Each box plot represents the median, interquartile range, minimum, and maximum values. *The data are statistically significantly different from the F-Con group (p < 0.05) | PMC9395442 | 431_2022_4516_Fig3_HTML.jpg |
0.45049 | 22697f40b0e5462783012e5d13d8113d | Comparison of the gut microbiota in fecal samples from the F-Con group (n = 9), F-CXM group (n = 13), and F-CXM + CFX group (n = 3). A and B Microbial community bar plot of the gut microbiota in fecal samples at the phylum and genus levels; C and D Kruskal–Wallis rank-sum test of the gut microbiota abundance in fecal samples at the phylum and genus levels; E LEfSe analysis cladogram of distinct bacteria in fecal samples at the phylum level; F LDA score of distinct bacteria in fecal samples at the genus level; G microbial community heatmap regarding the gut microbiota abundance in fecal samples. Red cells indicate increased; blue cells indicate decreased | PMC9395442 | 431_2022_4516_Fig4_HTML.jpg |
0.431659 | fdef0526263d4d1abd17004f7f439ada | a and b-diversity indices of the gut microbiota in fecal samples from the CXM-treated group (F-CXM, n = 13) and CXM-treated group at the follow-up visits (F-CXM-FV, n = 5). A Observed OTUs in the gut microbiota in fecal samples; B cloud plot of the Chao1 estimator regarding the gut microbial community richness in fecal samples; C cloud plot of the Shannon index regarding the gut microbial community diversity in fecal samples; D multiple-samples PCoA analysis regarding the difference in the microbial community composition in fecal samples. Blue circles represent samples of the F-CXM group; yellow squares represent samples of the F-CXM-FV group. Each box plot represents the median, interquartile range, minimum, and maximum values. *The data are statistically significantly different from the F-CXM group (p < 0.05) | PMC9395442 | 431_2022_4516_Fig5_HTML.jpg |
0.495428 | a511c0a8197e4d10b226cb4b3bc5cae2 | Comparison of the gut microbiota in fecal samples from the F-CXM group (n = 13) and F-CXM-FV group (n = 5). A and B Microbial community bar plot of the gut microbiota in fecal samples at the phylum and genus levels; C and D Wilcoxon rank-sum test of the gut microbiota abundance in fecal samples at the phylum and genus levels; E LEfSe analysis cladogram of distinct bacteria in fecal samples at the phylum level; F LDA score of distinct bacteria in fecal samples at the genus level; G microbial community heatmap regarding the gut microbiota abundance in fecal samples. Red cells indicate increased; blue cells indicate decrease | PMC9395442 | 431_2022_4516_Fig6_HTML.jpg |
0.408493 | 5a26cfe706d746eabc7a11ba4f44484e | Heatmap regarding of the relative ARG abundance of the gut microbiota in fecal samples. A Relative ARG abundance of the gut microbiota in fecal samples from the F-Con group (n = 9), F-CXM group (n = 13), and F-CXM + CFX group (n = 3); B relative ARG abundance of the gut microbiota in fecal samples from the F-CXM group (n = 13) and F-CXM-FV group (n = 5). Red cells indicate increased; green cells indicate decreased | PMC9395442 | 431_2022_4516_Fig7_HTML.jpg |
0.42102 | e680c4776e4944ca9eb3ce91ec5ecf7a | Effect of pancreatin on jejunal transporter gene expression in piglets (* represents significant differences, p < 0.05). | PMC9395744 | fphys-13-906522-g001.jpg |
0.492198 | fc2c7b1af2274ce389125dedd3f4a851 | Morphology of duodenum (A), jejunum (B), and ileum (C) of piglets fed with control and 500 mg/kg pancreatin. | PMC9395744 | fphys-13-906522-g002.jpg |
0.441131 | 103795b8eb1c42ff8326e2ca065681e9 |
(A,B) Rarefaction Curve. (C-F) Box graph of group differences by four alpha diversity indices. (G) Principal Component Analysis. (H) Box graph of β-diversity based on Weighted Unifrac. | PMC9395744 | fphys-13-906522-g003.jpg |
0.475798 | 5f2165e9eda443b7bb80a2e37c84e428 |
(A) Venn diagram of the OTU analysis of intestinal microorganisms. (B) TOP 10 of the genus relative abundance histogram at the genus level. (C) TOP 10 of the species relative abundance histogram at the species level. (D) LDA effect size analysis. (E) PICRUSt functional annotation clustering heat map. | PMC9395744 | fphys-13-906522-g004.jpg |
0.421216 | cfc450e9d98d4ad19086c93860f4f824 | Flowchart of the children infected with SARS-CoV-2 included in the study cohort. Polymerase chain reaction (PCR). Period of the third wave: December 1, 2020–April 30, 2021. Period of the fourth wave: June 1, 2021–October 10 (the end of analysis) | PMC9395901 | 431_2022_4531_Fig1_HTML.jpg |
0.4456 | 02a139d213e24047a3f8a26a352bba9d | (A) Rate of febrile illness by age in the third and fourth waves. (B) Rate of respiratory systems by age among symptomatic children in the third and fourth wave | PMC9395901 | 431_2022_4531_Fig2_HTML.jpg |
0.437666 | dd13008ba1d249999ee5c39f73b73ec7 | The Australian national palliative care standards. Standard 1 pertains to the patient’s multi-faceted needs, and standard 2 involves consultative drafting of personalised care plans for patients [4]. Standard 3 addresses the needs of the patient’s carers/family, and standard 4 fine-tunes consultative planned care [4]. Standard 5 proffers smooth transitions and interdisciplinary care, and standard 6 tends to grief/loss support for families and carers [4]. Standards 7 and 8 pertain to priming palliative service environment and quality [4]. Standard 9 optimises staff qualifications, efficiency, training, and performance [4]. | PMC9397021 | nursrep-12-00058-g001.jpg |
0.447773 | bfa7f97259c84483bed36951f98ec1eb | Standardized coefficients of the relationships between perceived social support and child behavior problems across three time points. T1 = baseline; T2 = 6 months; T3 = 12 months; Dotted lines represent non-significant associations; *p < 0.05. | PMC9397722 | fresc-02-679974-g0001.jpg |
0.4213 | f2bf90bdebc340839226ab362b80fb81 | Standardized coefficients of the relationships between perceived social support and stress across three time points. T1 = baseline; T2 = 6 months; T3 = 12 months; Dotted lines represent non-significant associations; *p < 0.05. | PMC9397722 | fresc-02-679974-g0002.jpg |
0.474271 | f811f3358fb9441aa73f7ebf443e386e | Relatedness of whole genome alignment of 20 P. agardhii isolates from Sandusky Bay, Lake Erie.The top of the matrix is the average nucleotide identity (ANI) common between two isolates. The bottom of the matrix is the alignment percentage (AP) common between two isolates. The lowest AP value suggests a common genome core of 45%. | PMC9398003 | pone.0273454.g001.jpg |
0.444418 | 295daf5434e1443b87e40a329c3320ac | Whole genome phylogenetic tree based on (AP/ANI) reveals distinct grouping of P. agardhii isolates.Since the grouping is the same using either AP and ANI, only the tree generated using ANI and the UPGMA method is shown here. The bar represents the horizontal distance matrix used to scale the branch length as a function of substitutions per site. | PMC9398003 | pone.0273454.g002.jpg |
0.412382 | 377bbb3c33b646eeabd87971a6d57290 | Concatenated conserved gene phylogenetic tree of P. agardhii isolates.Tree generated by concatenating the alignments of all Sandusky Bay isolates alongside two P. agardhii and two P. rubescens reference sequences. Genes included in concatenation include ftsz, gyrB, ntcA, rpoB, and rpoC1. The bar represents the horizontal distance matrix used to scale the branch length as a function of substitutions per site. | PMC9398003 | pone.0273454.g003.jpg |
0.384225 | 3aade7e445274b559aa4ec0a1a3f09db | Alignments of unique secondary metabolite clusters as references for the relatedness of sequences between isolates.Reference sequence is highlighted in yellow and includes gene annotations for the clusters. Black segments in the non-highlighted sequences indicate points of difference, grey segments indicate similar regions, and the lines indicate regions of no coverage. A. Microcystin (mcy) cluster. B.Aeruginosin (aer) cluster. C. Anabaenapeptin (apn) cluster. D. Cyanopeptin (oci) cluster. E. Microviridin (mvd) cluster. F. Prenylagaramide cluster (pag). For which isolates were collapsed into each head sequence, see S4 Table. | PMC9398003 | pone.0273454.g004.jpg |
0.484684 | 486852e9f0364c97ab3780fb43d305f4 | Oligotype phylogenetic tree, generated by the concatenation of the alignments for mcy, oci, aer, apn, mvd, and pag.The table relates presence and absence of specific secondary metabolite gene clusters to understand the relatedness of each isolate. The bar represents the horizontal distance matrix used to scale the branch length as a function of substitutions per site. | PMC9398003 | pone.0273454.g005.jpg |
0.433109 | aa7099ab57c24ba5a49787618a760c67 | Common and unique CRISPR-Cas systems found in P. agardhii isolates of Sandusky Bay. | PMC9398003 | pone.0273454.g006.jpg |
0.439712 | 8762f7fec87c4104913dddcc836caf16 | Nitrogen acquisition and storage genes found in P. agardhii.A. Sequence alignment of the nrtABCD cluster in reference NIES-204 and the P. agardhii isolates from Sandusky Bay. B. Sequence alignment of cyanophycin synthetase cphA1. C. Partial sequence alignment of cyanophycinase (cphB) and cyanophycin synthetase chpA2 operon. | PMC9398003 | pone.0273454.g007.jpg |
0.445892 | f3e43ba797b8430884fb1db60f3b762c |
(A) MRCP demonstrated that neoplasm was in the distal common bile duct. (B) Duodenoscopy showed that the biliary stent was filled and blocked by tumor tissue and bile mud. | PMC9399461 | fonc-12-890735-g001.jpg |
0.5039 | 8c1b969482134d4fa517795166c6700f | Curve of bilirubin change. | PMC9399461 | fonc-12-890735-g002.jpg |
0.524312 | 6d772949372c4b36820c80295433827f | A conceptual framework of CACBs’ brand value measured dimension. | PMC9399744 | fpsyg-13-933224-g001.jpg |
0.518123 | 38ef142b6f1c4e1281379539df4fd87d | Brand value dimension extraction process. | PMC9399744 | fpsyg-13-933224-g002.jpg |
0.450666 | 3db640e107f64de2b79a3b897441ee32 | SDS-PAEG gel showing the presence and location of the Acinetobacter baumannii’s OMPs. Lane A is the protein standards and lane B is the OMPs. OMPS, Outer membrane proteins. | PMC9400467 | RPS-17-360-g002.jpg |
0.421135 | ea09fb62a9d84f06820b7d16671f4cca | Zeta potential charts of (A) PLGA and (B) outer membrane proteins-PLGA. PLGA, Poly (lactic-co-glycolic acid). | PMC9400467 | RPS-17-360-g003.jpg |
0.457872 | dc338a4ea5044898acc9a3d77d7f7d8c | Atomic force microscope images of (A) PLGA and (B) OMP-PLGA. OMP-PLGA, Outer membrane proteins- poly (lactic-co-glycolic acid). | PMC9400467 | RPS-17-360-g004.jpg |
0.505105 | 23509b5370a74e11afae2ba637ca7962 | The structural analysis results of (A) PLGA and (B) OMP-PLGA by FTIR analysis. OMP-PLGA, Outer membrane proteins-poly (lactic-co-glycolic acid). | PMC9400467 | RPS-17-360-g005.jpg |
0.45744 | 973ffd516bb04adf9298cef77dd27f4d | In vitro release of OMPs from OMP-PLGA NPs. OMP-PLGA, Outer membrane proteins-poly (lactic-co- glycolic acid). | PMC9400467 | RPS-17-360-g006.jpg |
0.44955 | bc4287d0f5b4490bbaa83d3bb6db7df3 | Specific serum IgG titers against pure OMP and OMP-PLGA in three vaccination periods in the dilution 1/256: (mean level of antibody in 10 mice). *P < 0.05, **P < 0.01, and ***P < 0.001 indicate significant differences between groups. OMP-PLGA, Outer membrane proteins-poly (lactic-co-glycolic acid). | PMC9400467 | RPS-17-360-g007.jpg |
0.42824 | 39b959744325420398f4ee6063e3efa9 | The percent of opsonophagocytosis activity in various serum dilutions of experimental mice that were immunized with OMP and OMP-PLGA. There was a significant difference between the two groups in all serum dilutions but significant differences in % inhibition of opsonophagocytic killing activity between NS and PLGA recipient groups were not significant. ***P < 0.001 Indicates significant differences between defined groups. OMP-PLGA, Outer membrane proteins-poly (lactic-co-glycolic acid), NS, normal saline. | PMC9400467 | RPS-17-360-g008.jpg |
0.420155 | 64bb2a4f810843ffa8bef9c138fe6a3d | Level of protection against Acinetobacter baumannii infection in two groups receiving OMP-PLGA and OMP in the 1:100 dilution. ***P < 0.001 Indicates significant differences. OMP-PLGA, Outer membrane proteins-poly (lactic-co-glycolic acid). | PMC9400467 | RPS-17-360-g009.jpg |
0.467807 | 5b34f7cc67c440d0ac3efad8c198176a | Mechanism of particle-oil adsorption in coal flotation with kerosene (a) and sunflower oil (b). This figure is reproduced from ref. 25 with permission from Springer-Verlag GmbH Germany, Copyright 2009. | PMC9400654 | d2ra02861a-f1.jpg |
0.426183 | 6374857e205b4704986203d9d6c4cf0d | Interaction between mixture emulsion and low-rank coal. This figure is reproduced from ref. 71 with permission from Elsevier, Copyright 2020. | PMC9400654 | d2ra02861a-f10.jpg |
0.415348 | 5c8215528a774fc4a1c64827790dff4b | Working strategy of Triton X-100 in reverse flotation of low-rank coal. This figure is adopted from ref. 74 with permission from Elsevier, Copyright 2021. | PMC9400654 | d2ra02861a-f11.jpg |
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