prognosis/cardio-docs-qa · Datasets at Hugging Face

Outcomes can be what?

intermediate- term or acute outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Outcomes can be what?. ### Response: intermediate- term or acute outcomes.

What was a sub-stantial part of the study?

The ability to use outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a sub-stantial part of the study?. ### Response: The ability to use outcomes.

What was the ability to use outcomes as opposed to processes of care?

performance measures

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the ability to use outcomes as opposed to processes of care?. ### Response: performance measures.

What was a sub-stantial part of the discussion by the writing group?

The ability to use outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was a sub-stantial part of the discussion by the writing group?. ### Response: The ability to use outcomes.

What weighed substantially in the decisions on which performance measures to put forth?

consideration of feasibility of measurement and harmonization with existing performance measures from other organizations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What weighed substantially in the decisions on which performance measures to put forth?. ### Response: consideration of feasibility of measurement and harmonization with existing performance measures from other organizations.

What is the primary source for review of potential performance measures?

Literature Review

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the primary source for review of potential performance measures?. ### Response: Literature Review.

What is associated with improved postoperative outcomes in patients undergoing coronary artery bypass grafting?

Preoperative aspirin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with improved postoperative outcomes in patients undergoing coronary artery bypass grafting?. ### Response: Preoperative aspirin therapy.

What is the doi: 10.1161/CIRCULATIONAHA.104.522805.

Circulation. 2005;112(suppl):I286–I292

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the doi: 10.1161/CIRCULATIONAHA.104.522805.. ### Response: Circulation. 2005;112(suppl):I286–I292.

What is the acronym for the American College of Cardiology Foundation?

American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the American College of Cardiology Foundation?. ### Response: American Heart Association Task Force on Practice Guidelines.

What does the acronym ACCF/AHA focus on in 2012?

the guideline for the management of patients with unstable angina/non-ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does the acronym ACCF/AHA focus on in 2012?. ### Response: the guideline for the management of patients with unstable angina/non-ST-elevation myocardial infarction.

What did the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines replace?

2011 focused update

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines replace?. ### Response: 2011 focused update.

What is the name of the group that updated the 2007 guideline and replaced the 2011 focused update?

American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the group that updated the 2007 guideline and replaced the 2011 focused update?. ### Response: American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

What is the name of the person who was a part of Casey DE Jr.?

O’Gara

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was a part of Casey DE Jr.?. ### Response: O’Gara.

What is another name for Fesmire FM?

Franklin BA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Fesmire FM?. ### Response: Franklin BA.

Who is a member of the family that is based in Newby LK?

Ornato JP

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is a member of the family that is based in Newby LK?. ### Response: Ornato JP.

Where is Tracy CM?

American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Tracy CM?. ### Response: American College of Cardiology Foundation.

What is the 2013 ACCF/AHA guideline for the management of ST-elevation?

a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2013 ACCF/AHA guideline for the management of ST-elevation?. ### Response: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

What is the name of the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?

Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction?. ### Response: Task Force on Practice Guidelines.

What is a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?

2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines?. ### Response: 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction.

Circulation 2013;127:e362–e425.

Foundation/American Heart Association Task Force on Practice Guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation 2013;127:e362–e425.. ### Response: Foundation/American Heart Association Task Force on Practice Guidelines.

What did Harlan BJ, DeMots H, Calvin L, Rösch J. fail to improve after coronary-artery bypass: a controlled, randomized study?

patency of grafts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did Harlan BJ, DeMots H, Calvin L, Rösch J. fail to improve after coronary-artery bypass: a controlled, randomized study?. ### Response: patency of grafts.

What did failure of antiplatelet and anticoagulant therapy improve?

patency of grafts

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did failure of antiplatelet and anticoagulant therapy improve?. ### Response: patency of grafts.

What is the effect of antithrombotic therapy on patency rates of saphenous vein coronary artery bypass grafts?

improved postoperative outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of antithrombotic therapy on patency rates of saphenous vein coronary artery bypass grafts?. ### Response: improved postoperative outcomes.

What was the name of the 1982 issue of J Thorac Cardiovasc Surg?

N Engl J Med.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the 1982 issue of J Thorac Cardiovasc Surg?. ### Response: N Engl J Med..

What is the effect of anti-platelet therapy on saphenous vein coronary artery bypass graft patency?

improved postoperative outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the effect of anti-platelet therapy on saphenous vein coronary artery bypass graft patency?. ### Response: improved postoperative outcomes.

Circulation. 1983;68(pt 2):II218–II221.

14

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Circulation. 1983;68(pt 2):II218–II221.. ### Response: 14.

What is a benefit of perioperative dipyridamole and aspirin therapy on early postoperative vein-graft patency?

A platelet-inhibitor-drug trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a benefit of perioperative dipyridamole and aspirin therapy on early postoperative vein-graft patency?. ### Response: A platelet-inhibitor-drug trial.

What is the name of the clinical trial in coronary-artery bypass operations?

A platelet-inhibitor-drug trial

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the clinical trial in coronary-artery bypass operations?. ### Response: A platelet-inhibitor-drug trial.

What is the name of the person who was involved in the investigation of the case?

Chesebro JH

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the person who was involved in the investigation of the case?. ### Response: Chesebro JH.

What is another name for Elveback LR?

Clements

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another name for Elveback LR?. ### Response: Clements.

Who was involved with the investigation?

American College of Cardiology Foundation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who was involved with the investigation?. ### Response: American College of Cardiology Foundation.

What is the name of the author of The Birth of Pediatric Primary Hypertension?

Joshua Samuels

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the author of The Birth of Pediatric Primary Hypertension?. ### Response: Joshua Samuels.

When was Joshua Samuels a kid?

03/30/2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was Joshua Samuels a kid?. ### Response: 03/30/2023.

What type of tachycardia are beta blockers and calcium channel blockers used for?

focal atrial tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What type of tachycardia are beta blockers and calcium channel blockers used for?. ### Response: focal atrial tachycardia.

Where can you find the latest version of this article?

http://ahajournals.org

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where can you find the latest version of this article?. ### Response: http://ahajournals.org.

When was this article published?

April 23, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was this article published?. ### Response: April 23, 2023.

What is the name of the publication that was published in 2012?

kidney-international

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the publication that was published in 2012?. ### Response: kidney-international.

When was the last issue of the Kidney International Journal published?

2012

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the last issue of the Kidney International Journal published?. ### Response: 2012.

What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?

2019

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the ACC/AHA guideline on the Primary Prevention of Cardiovascular Disease?. ### Response: 2019.

What was the 10-year risk of “hard ASCVD”?

8.7%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the 10-year risk of “hard ASCVD”?. ### Response: 8.7%,.

How much was the risk of the expanded asCVD end-point that included coronary revascularization?

10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much was the risk of the expanded asCVD end-point that included coronary revascularization?. ### Response: 10%..

What percentage included coronary revascularization?

10%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage included coronary revascularization?. ### Response: 10%..

After 5.6 years, those assigned to rosuvastatin 10 mg per day showed significant absolute risk reduction in both co-primary end-points with an acceptable safety record?

S4.3-9

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: After 5.6 years, those assigned to rosuvastatin 10 mg per day showed significant absolute risk reduction in both co-primary end-points with an acceptable safety record?. ### Response: S4.3-9.

What was the median follow-up of 1.9 years?

those assigned to a high-intensity statin dose of rosuvastatin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median follow-up of 1.9 years?. ### Response: those assigned to a high-intensity statin dose of rosuvastatin.

What was the name of the RCT that evaluated rosuvastatin in a high-intensity statin dose?

JUPITER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the name of the RCT that evaluated rosuvastatin in a high-intensity statin dose?. ### Response: JUPITER.

What did the participants in the JUPITER RCT achieve in relation to LDL-C lowering and ASCVD?

greater reductions in ASCVD outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the participants in the JUPITER RCT achieve in relation to LDL-C lowering and ASCVD?. ### Response: greater reductions in ASCVD outcomes.

What is the net benefit of LDL-C-lowering therapy greater with greater reductions in?

ASCVD outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the net benefit of LDL-C-lowering therapy greater with greater reductions in?. ### Response: ASCVD outcomes.

What is reasonable to use a high-intensity statin to lower by 50%?

LDL-C

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is reasonable to use a high-intensity statin to lower by 50%?. ### Response: LDL-C.

What percentage of LDL-C is lower?

≥50%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of LDL-C is lower?. ### Response: ≥50%..

What is the 10-year risk of ASCVD?

≥20%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 10-year risk of ASCVD?. ### Response: ≥20%..

Who enrolled men 50 and women 60 years of age with high-sensitivity C-reactive pro-tein values?

JUPITER

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who enrolled men 50 and women 60 years of age with high-sensitivity C-reactive pro-tein values?. ### Response: JUPITER.

How many mg per day of rosuvastatin were participants randomly assigned to?

20

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many mg per day of rosuvastatin were participants randomly assigned to?. ### Response: 20.

What was the median LDL-C reduc-tion of rosuvastatin?

50%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the median LDL-C reduc-tion of rosuvastatin?. ### Response: 50%.

How long did it take for ASCVD risk to be reduced?

1.9 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long did it take for ASCVD risk to be reduced?. ### Response: 1.9 years.

What did the USPSTF systematic review of statin therapy show?

reduced risk of all-cause and cardio-vascular mortality and ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the USPSTF systematic review of statin therapy show?. ### Response: reduced risk of all-cause and cardio-vascular mortality and ASCVD events.

What did a review of statin therapy in primary prevention show reduced risk of?

all-cause and cardio-vascular mortality and ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a review of statin therapy in primary prevention show reduced risk of?. ### Response: all-cause and cardio-vascular mortality and ASCVD events.

What did the review show greater absolute benefits in those at greater base-line risk?

statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the review show greater absolute benefits in those at greater base-line risk?. ### Response: statin therapy.

What is the need for aggressive and safe risk reduction in the highest-risk groups?

follow-up LDL-C testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the need for aggressive and safe risk reduction in the highest-risk groups?. ### Response: follow-up LDL-C testing.

What is needed to determine adherence and adequacy of effect of the statin prescribed?

follow-up LDL-C testing

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is needed to determine adherence and adequacy of effect of the statin prescribed?. ### Response: follow-up LDL-C testing.

Most patients 40 to 75 years of age with diabe-tes are at intermediate or high risk?

ASCVD events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Most patients 40 to 75 years of age with diabe-tes are at intermediate or high risk?. ### Response: ASCVD events.

How many double-blind primary-prevention RCTs showed significant reductions in ASCVD events in large cohorts with diabetes in this age range?

Three of 4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many double-blind primary-prevention RCTs showed significant reductions in ASCVD events in large cohorts with diabetes in this age range?. ### Response: Three of 4.

What did a meta-analysis of these trials find associated with moderate-intensity statin therapy?

a risk reduction of 25%,

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a meta-analysis of these trials find associated with moderate-intensity statin therapy?. ### Response: a risk reduction of 25%,.

What was associated with a risk reduction of 25%,S4.3-13?

moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was associated with a risk reduction of 25%,S4.3-13?. ### Response: moderate-intensity statin therapy.

What is indicated for primary prevention in patients 40 to 75 years old?

moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for primary prevention in patients 40 to 75 years old?. ### Response: moderate-intensity statin therapy.

What is indicated for primary prevention in patients 40 to 75 years of age?

moderate-intensity statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is indicated for primary prevention in patients 40 to 75 years of age?. ### Response: moderate-intensity statin therapy.

What is the most common medical complication inaSAH?

Fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the most common medical complication inaSAH?. ### Response: Fever.

What has fever of noninfectious origin been associated with?

severity of injury, amount ofhemorrhage, and development of vasospasm

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has fever of noninfectious origin been associated with?. ### Response: severity of injury, amount ofhemorrhage, and development of vasospasm.

What has been associated with severity of injury, amount of hemorrhage, and development of vasospasm?

The presence of fever of noninfectious (central)origin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been associated with severity of injury, amount of hemorrhage, and development of vasospasm?. ### Response: The presence of fever of noninfectious (central)origin.

What may be a marker of a systemic inflammatory state triggered?

fever

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be a marker of a systemic inflammatory state triggered?. ### Response: fever.

When did Stroke June 2012 occur?

April 28, 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did Stroke June 2012 occur?. ### Response: April 28, 2023.

What should be administered preoperatively to patients undergoing CABG?

Non–enteric-coated aspirin

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be administered preoperatively to patients undergoing CABG?. ### Response: Non–enteric-coated aspirin.

How much aspirin should be given daily?

81 mg to 325 mg

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much aspirin should be given daily?. ### Response: 81 mg to 325 mg.

What is the Level of Evidence?

B)Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the Level of Evidence?. ### Response: B)Class IIb1.

What should be discontinued for at least 5 days before surgery in patients referred for elective CABG?

clopidogrel and ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 5 days before surgery in patients referred for elective CABG?. ### Response: clopidogrel and ticagrelor.

How long should clopidogrel and ticagrelor be discontinued before surgery?

5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel and ticagrelor be discontinued before surgery?. ### Response: 5 days.

When should prasugrel be discontinued?

7 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should prasugrel be discontinued?. ### Response: 7 days.

How long should clopidogrel and ticagrelor be discontinued in patients referred for urgent CABG?

1 to 4 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should clopidogrel and ticagrelor be discontinued in patients referred for urgent CABG?. ### Response: 1 to 4 days.

What should be discontinued for at least 24 hours to reduce major bleeding?

clopidogrel and ticagrelor

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 24 hours to reduce major bleeding?. ### Response: clopidogrel and ticagrelor.

When should short acting intravenous GP IIb/IIIa inhibitors be discontinued?

2 to 4 hours before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should short acting intravenous GP IIb/IIIa inhibitors be discontinued?. ### Response: 2 to 4 hours before surgery.

What should be discontinued for at least 2 to 4 hours before surgery?

short-acting intrave-nous GP IIb/IIIa inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be discontinued for at least 2 to 4 hours before surgery?. ### Response: short-acting intrave-nous GP IIb/IIIa inhibitors.

How long should abciximab be discontinued?

12 hours

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long should abciximab be discontinued?. ### Response: 12 hours.

What is the level of evidence?

B)Class IIb1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the level of evidence?. ### Response: B)Class IIb1.

What is performed in 7% to 13% of patients hospitalized with NSTE-ACS?

CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is performed in 7% to 13% of patients hospitalized with NSTE-ACS?. ### Response: CABG.

How long after clopidogrel or ticagrelor has been discontinued is it reasonable to perform surgery?

less than 5 days

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after clopidogrel or ticagrelor has been discontinued is it reasonable to perform surgery?. ### Response: less than 5 days.

What percentage of NSTEMI patients undergo CABG?

one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of NSTEMI patients undergo CABG?. ### Response: one third.

What percentage of patients with NSTEMI undergo CABG within 48 hours of hospital admission?

Approximately one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What percentage of patients with NSTEMI undergo CABG within 48 hours of hospital admission?. ### Response: Approximately one third.

What was performed at a median time of 73 hours after admission in these patients?

CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was performed at a median time of 73 hours after admission in these patients?. ### Response: CABG.

How much is the in-hospital mortality in patients undergoing CABG?

3.7%.

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much is the in-hospital mortality in patients undergoing CABG?. ### Response: 3.7%..

What is the percentage of patients with NSTEMI undergoing CABG?

one third

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the percentage of patients with NSTEMI undergoing CABG?. ### Response: one third.

What is given in the 2011 CABG CPG?

Recommendations for management of patients treated with oral and intravenous antiplatelet agents

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is given in the 2011 CABG CPG?. ### Response: Recommendations for management of patients treated with oral and intravenous antiplatelet agents.

Preoperative aspirin reduces what?

operative morbidity and mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preoperative aspirin reduces what?. ### Response: operative morbidity and mortality.

How can CABG be performed safely?

aspirin therapy with only a modest increase in bleeding risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How can CABG be performed safely?. ### Response: aspirin therapy with only a modest increase in bleeding risk.

What can be performed safely in patients on aspirin therapy?

CABG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be performed safely in patients on aspirin therapy?. ### Response: CABG.

What is associated with an increase in post-CABG bleeding and the need for transfusion?

The use of P2Y12 inhibitors

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is associated with an increase in post-CABG bleeding and the need for transfusion?. ### Response: The use of P2Y12 inhibitors.

Clopidogrel and ticagrelor should be discontinued at least at least what?

5 days before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Clopidogrel and ticagrelor should be discontinued at least at least what?. ### Response: 5 days before surgery.

When should clopidogrel and ticagrelor be discontinued?

5 days before surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should clopidogrel and ticagrelor be discontinued?. ### Response: 5 days before surgery.

What should prasugrel be discontinued at least 7 days before surgery in patients referred for elective CABG?

clopidogrel

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should prasugrel be discontinued at least 7 days before surgery in patients referred for elective CABG?. ### Response: clopidogrel.

When should timing of CABG in patients with NSTE-ACS treated with a P2Y12 inhibitor330 reflect?

a balance of the potential increase in bleeding

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When should timing of CABG in patients with NSTE-ACS treated with a P2Y12 inhibitor330 reflect?. ### Response: a balance of the potential increase in bleeding.

What should inhibitor330 reflect a balance of the potential increase in bleeding against the potential benefits of not delaying surgery 5 to 7 days?

P2Y12

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should inhibitor330 reflect a balance of the potential increase in bleeding against the potential benefits of not delaying surgery 5 to 7 days?. ### Response: P2Y12.

What is increased when CABG is performed 24 hours after dis-continuation of clopidogrel?

The risk of major bleeding complications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is increased when CABG is performed 24 hours after dis-continuation of clopidogrel?. ### Response: The risk of major bleeding complications.