prognosis/cardio-docs-qa · Datasets at Hugging Face

Recommendation from previous CPG that has been removed based on review of the evidence Not reviewed Not changed Recommandation that was carried forward to the updated CPG but for which the evidence has not been reviewed?

Amended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Recommendation from previous CPG that has been removed based on review of the evidence Not reviewed Not changed Recommandation that was carried forward to the updated CPG but for which the evidence has not been reviewed?. ### Response: Amended.

What has not been reviewed Amended Recommendation from previous CPG that has been carried forward to the updated CPG where the evidence hasn't been reviewed and a minor amendment has been made What has been removed because it was deemed out of date?

the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has not been reviewed Amended Recommendation from previous CPG that has been carried forward to the updated CPG where the evidence hasn't been reviewed and a minor amendment has been made What has been removed because it was deemed out of date?. ### Response: the evidence.

What was removed because it was out of scope for the updated CPG?

Recommendation from previous CPG

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was removed because it was out of scope for the updated CPG?. ### Response: Recommendation from previous CPG.

What was adapted from the NICE guideline manual?

recommendation categories

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was adapted from the NICE guideline manual?. ### Response: recommendation categories.

What is NICE: National Institute for Health and Care Excellence?

clinical practice guideline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is NICE: National Institute for Health and Care Excellence?. ### Response: clinical practice guideline.

What were recommendations first categorized by whether or not they were based on an updated review of?

the evidence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations first categorized by whether or not they were based on an updated review of?. ### Response: the evidence.

What were recommendations categorized as if evidence had been reviewed?

“New -added,” “New -replaced,” “Not changed,” “Amended,” or “Deleted.”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations categorized as if evidence had been reviewed?. ### Response: “New -added,” “New -replaced,” “Not changed,” “Amended,” or “Deleted.”.

What were original recommendations that were not in the 2014 VA/DoD Dyslipidemia CPG?

“Reviewed, New- added”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were original recommendations that were not in the 2014 VA/DoD Dyslipidemia CPG?. ### Response: “Reviewed, New- added”.

What were recommendations carried forward from the previous version of the CPG?

unchanged

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations carried forward from the previous version of the CPG?. ### Response: unchanged.

How were recommendations modified to align with the updated review of evidence?

“Reviewed, New -replaced

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were recommendations modified to align with the updated review of evidence?. ### Response: “Reviewed, New -replaced.

What was carried forward from the previous version of the CPG unchanged?

Recommendations categorized as “Reviewed, Not changed”

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was carried forward from the previous version of the CPG unchanged?. ### Response: Recommendations categorized as “Reviewed, Not changed”.

What were recommendations carried forward to the updated CPG with a review of the evidence?

Amended

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What were recommendations carried forward to the updated CPG with a review of the evidence?. ### Response: Amended.

What is the risk of embolic stroke in patients with anterior MI and left ventricular thrombus?

increased

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of embolic stroke in patients with anterior MI and left ventricular thrombus?. ### Response: increased.

What affects 6% to 15% of patients with anterior MI?

left ventric-ular thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What affects 6% to 15% of patients with anterior MI?. ### Response: left ventric-ular thrombus.

What is the name of the article that was downloaded from http://ahajournals.org on April 28, 2023?

gestive heart failure. Importantly, the risk of embolic stroke is increased in patients with anterior MI and left ventricular thrombus. Contemporary studies have found that left ventric-ular thrombus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the article that was downloaded from http://ahajournals.org on April 28, 2023?. ### Response: gestive heart failure. Importantly, the risk of embolic stroke is increased in patients with anterior MI and left ventricular thrombus. Contemporary studies have found that left ventric-ular thrombus.

How many RCTs examined the effect of ACEI CCBversus CCB in patients with CKD without DM?

25

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs examined the effect of ACEI CCBversus CCB in patients with CKD without DM?. ### Response: 25.

What is Supplementary Table 25?

RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is Supplementary Table 25?. ### Response: RCTs.

RCTs examining the effect of ACE CCBversus CCB in patients with CKD without DM?

þCCBversus ACEI in patients with CKD without DM [continuous outcomes].Supplementary Table 26 . RCTs examining the effect of ACEI þCCBversus CCB in patients with CKD without DM [categorical outcomes].Supplementary Table 27

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RCTs examining the effect of ACE CCBversus CCB in patients with CKD without DM?. ### Response: þCCBversus ACEI in patients with CKD without DM [continuous outcomes].Supplementary Table 26 . RCTs examining the effect of ACEI þCCBversus CCB in patients with CKD without DM [categorical outcomes].Supplementary Table 27.

How many RCTs examined the effect of b-blockerversus CCB in patients with CKD without DM?

Supplementary Table 31

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many RCTs examined the effect of b-blockerversus CCB in patients with CKD without DM?. ### Response: Supplementary Table 31.

b-blockerversus CCB in patients with CKD without DM [continuous outcomes]?

central-actingagent

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: b-blockerversus CCB in patients with CKD without DM [continuous outcomes]?. ### Response: central-actingagent.

RCTs examining the effect of central-actingagent versus what?

CCB

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: RCTs examining the effect of central-actingagent versus what?. ### Response: CCB.

What is the general population comparing ACEI diuretic versus placebo?

RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the general population comparing ACEI diuretic versus placebo?. ### Response: RCTs.

CKD with DM subgroups [categoricaloutcomes]?

ACEI þdiuretic versus placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: CKD with DM subgroups [categoricaloutcomes]?. ### Response: ACEI þdiuretic versus placebo.

General population RCTs comparing ACEIdiuretic versus placebo in what group?

CKD with DM

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: General population RCTs comparing ACEIdiuretic versus placebo in what group?. ### Response: CKD with DM.

How many general population RCTs comparing CCBversus active control in CKD subgroups with and without DM?

36

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many general population RCTs comparing CCBversus active control in CKD subgroups with and without DM?. ### Response: 36.

How many Kidney International Supplements (2012) 2, 357–362chapter 3?

362

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many Kidney International Supplements (2012) 2, 357–362chapter 3?. ### Response: 362.

What is the 2017 High Blood Pressure Clinical Practice Guideline e101 S10.1-7?

Whelton et al

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the 2017 High Blood Pressure Clinical Practice Guideline e101 S10.1-7?. ### Response: Whelton et al.

What is a prevalence of hypertension, awareness, treatment and control in the Hispanic Community Health Study/Study of Latinos?

Prevalence

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a prevalence of hypertension, awareness, treatment and control in the Hispanic Community Health Study/Study of Latinos?. ### Response: Prevalence.

What is APOL1 risk variants, race, and progression of chronic kidney disease?

eGFR decline

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is APOL1 risk variants, race, and progression of chronic kidney disease?. ### Response: eGFR decline.

What is the status of cardio-vascular disease and stroke in Hispanics/Latinos in the United States?

a science advisory from the American Heart Association

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the status of cardio-vascular disease and stroke in Hispanics/Latinos in the United States?. ### Response: a science advisory from the American Heart Association.

What gene variants associate with hypertension-attributed nephropa-thy and the rate of kidney function decline in African Americans?

Apolipoprotein L1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gene variants associate with hypertension-attributed nephropa-thy and the rate of kidney function decline in African Americans?. ### Response: Apolipoprotein L1.

What gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial?

Apolipoprotein L1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial?. ### Response: Apolipoprotein L1.

In what year did Kidney Int. 2013:83:114–20?

2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In what year did Kidney Int. 2013:83:114–20?. ### Response: 2013.

What is the race, APOL1 gene variant?

chronic kidney disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the race, APOL1 gene variant?. ### Response: chronic kidney disease.

What does race, APOL1 risk, and eGFR decline in the general population do?

Grams ME, Rebholz CM, Chen Y , et al. Race, APOL1 risk, and eGFR decline in the general population. J Am Soc Nephrol. 2016;27:2842–50.10.1.1. Racial and Ethnic Differences in Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does race, APOL1 risk, and eGFR decline in the general population do?. ### Response: Grams ME, Rebholz CM, Chen Y , et al. Race, APOL1 risk, and eGFR decline in the general population. J Am Soc Nephrol. 2016;27:2842–50.10.1.1. Racial and Ethnic Differences in Treatment.

What is the J Am Soc Nephrol. 2016;27:2842–50.10.1.1?

Racial and Ethnic Differences in Treatment

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the J Am Soc Nephrol. 2016;27:2842–50.10.1.1?. ### Response: Racial and Ethnic Differences in Treatment.

How are high-risk hypertensive patients randomly assigned to calcium channel blocker?

Clinical events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are high-risk hypertensive patients randomly assigned to calcium channel blocker?. ### Response: Clinical events.

How were high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor?

Clinical events

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor?. ### Response: Clinical events.

What did the trial to prevent heart attack do?

Major outcomes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the trial to prevent heart attack do?. ### Response: Major outcomes.

How were ALLHAT find-ings revisited?

in the context of subsequent analyses, other trials, and meta-analyses

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How were ALLHAT find-ings revisited?. ### Response: in the context of subsequent analyses, other trials, and meta-analyses.

What is the name of the drug that is used to treat hypertensive black and nonblack patients?

chlorthalidone

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug that is used to treat hypertensive black and nonblack patients?. ### Response: chlorthalidone.

What are the names of the drugs that are used in the treatment of hypertension?

chlorthalidone, amlodip-ine, and lisinopril

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the names of the drugs that are used in the treatment of hypertension?. ### Response: chlorthalidone, amlodip-ine, and lisinopril.

How many people were treated with chlorthalidone, amlodipine, and lisinopril?

black and nonblack patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many people were treated with chlorthalidone, amlodipine, and lisinopril?. ### Response: black and nonblack patients.

What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?

ALLHAT

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the acronym for the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial?. ### Response: ALLHAT.

Who is the ALLHAT Officers and Coordinators for?

ALLHAT Collaborative Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the ALLHAT Officers and Coordinators for?. ### Response: ALLHAT Collaborative Research Group.

Who is the Coordinator for the ALLHAT Collaborative Research Group?

ALLHAT Officers

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who is the Coordinator for the ALLHAT Collaborative Research Group?. ### Response: ALLHAT Officers.

What is the name of the research group that conducted a randomized trial of intensive versus standard blood pressure control?

SPRINT Research Group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the research group that conducted a randomized trial of intensive versus standard blood pressure control?. ### Response: SPRINT Research Group.

What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 125 of 127 112.

Page 125 of 127 112. Silverman MG, Ference BA, Im K, et al. Association between lowering LDL -C an d cardiovascular risk reduction among different therapeutic interventions: A systematic review and meta -analysis. JAMA. Sep 27 2016; 316(12):1289 -1297. PMID: 27673306. 113

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the VA/DoD Clinical Practice Guideline for the Management of Dyslipidemia for Cardiovascular Risk Reduction June 2020 Page 125 of 127 112.. ### Response: Page 125 of 127 112. Silverman MG, Ference BA, Im K, et al. Association between lowering LDL -C an d cardiovascular risk reduction among different therapeutic interventions: A systematic review and meta -analysis. JAMA. Sep 27 2016; 316(12):1289 -1297. PMID: 27673306. 113.

What does lowering LDL -C and cardiovascular risk reduction among different therapeutic interventions do?

reduce primary medication nonadherence to cardiovascular medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lowering LDL -C and cardiovascular risk reduction among different therapeutic interventions do?. ### Response: reduce primary medication nonadherence to cardiovascular medications.

What does lower intensified target LDL -c level of statin therapy result in?

higher risk of incident diabetes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does lower intensified target LDL -c level of statin therapy result in?. ### Response: higher risk of incident diabetes.

What is a higher risk of incident diabetes?

Lower intensified target LDL -c level of statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a higher risk of incident diabetes?. ### Response: Lower intensified target LDL -c level of statin therapy.

What does a higher risk of incident diabetes result in?

Lower intensified target LDL -c level of statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does a higher risk of incident diabetes result in?. ### Response: Lower intensified target LDL -c level of statin therapy.

What is the PMID for this meta -analysis?

25122464

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for this meta -analysis?. ### Response: 25122464.

When did a cohort study of patients discontinue statins?

Apr 2 2013

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did a cohort study of patients discontinue statins?. ### Response: Apr 2 2013.

What is the name of the study that looked at statin prescriptions after adverse reactions and patient outcomes?

A cohort study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the study that looked at statin prescriptions after adverse reactions and patient outcomes?. ### Response: A cohort study.

What was the PMID of Zhang H, Plutzky J, Shubina M, Turchin A?

28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID of Zhang H, Plutzky J, Shubina M, Turchin A?. ### Response: 28779871.

What did the Cleveland Clinic experience with statin intolerance do?

Treatment strategies

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the Cleveland Clinic experience with statin intolerance do?. ### Response: Treatment strategies.

What was the PMID for the study?

28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for the study?. ### Response: 28779871.

How did the study compare to placebo controlled trials?

Meta- analysis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How did the study compare to placebo controlled trials?. ### Response: Meta- analysis.

What is the prevalence of statin intolerance?

myalgia, myositis, myopathy, or myonecrosis

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the prevalence of statin intolerance?. ### Response: myalgia, myositis, myopathy, or myonecrosis.

What was the PMID of Law M, Rudnicka AR?

28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID of Law M, Rudnicka AR?. ### Response: 28779871.

When was the Am J Cardiol. Apr 17 2006;97(8A):52C -60C?

2006

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When was the Am J Cardiol. Apr 17 2006;97(8A):52C -60C?. ### Response: 2006.

What is the name of the drug used to treat veterans with statin-induced myopathy after vitamin D replenishment?

statin therapy

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the drug used to treat veterans with statin-induced myopathy after vitamin D replenishment?. ### Response: statin therapy.

What was the PMID for this study?

28738423

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the PMID for this study?. ### Response: 28738423.

How many days did it take for veterans to receive vitamin D?

120

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many days did it take for veterans to receive vitamin D?. ### Response: 120.

What can be safely resolved by vitamin d supplementation?

Statin intolerance

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be safely resolved by vitamin d supplementation?. ### Response: Statin intolerance.

What can statin intolerance due to myalgia, myositis, myopathy, or myonecrosis be resolved by?

vitamin d supplementation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can statin intolerance due to myalgia, myositis, myopathy, or myonecrosis be resolved by?. ### Response: vitamin d supplementation.

What is the PMID for Cochrane corner: Interventions to improve adherence to lipid lowering medication?

29440453

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for Cochrane corner: Interventions to improve adherence to lipid lowering medication?. ### Response: 29440453.

What does Pharmacy-based interventions reduce?

primary medication nonadherence to cardiovascular medications

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does Pharmacy-based interventions reduce?. ### Response: primary medication nonadherence to cardiovascular medications.

What is the PMID for Med Care?

25322157

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID for Med Care?. ### Response: 25322157.

How does information technology help improve adherence?

Improving adherence to cardiovascular disease medicat ions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does information technology help improve adherence?. ### Response: Improving adherence to cardiovascular disease medicat ions.

What does information technology help with?

Improving adherence to cardiovascular disease medicat ions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does information technology help with?. ### Response: Improving adherence to cardiovascular disease medicat ions.

What is the PMID of the National Center for Health Statistics?

28779871

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the PMID of the National Center for Health Statistics?. ### Response: 28779871.

Where is Hyattsville, MD: Centers for Disease Control?

Hyattsville

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is Hyattsville, MD: Centers for Disease Control?. ### Response: Hyattsville.

Where is the Centers for Disease Control and Prevention located?

Hyattsville, MD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where is the Centers for Disease Control and Prevention located?. ### Response: Hyattsville, MD.

What should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve?

Tachycardia

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve?. ### Response: Tachycardia.

What causes an increase in LA pressure?

Tachycardia should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What causes an increase in LA pressure?. ### Response: Tachycardia should be avoided because of the shortened diastolic LV filling time across the stenotic mitral valve.

What is the risk of elective noncardiac surgery in asymptomatic patients with significant rheumatic MS?

considerably higher

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of elective noncardiac surgery in asymptomatic patients with significant rheumatic MS?. ### Response: considerably higher.

What should be evaluated and treated as outlined in the rheumatic MS section?

stolic pressure >50 mm Hg, the risk of elective inter -mediate- to high-risk noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be evaluated and treated as outlined in the rheumatic MS section?. ### Response: stolic pressure >50 mm Hg, the risk of elective inter -mediate- to high-risk noncardiac surgery.

What are the overall hemodynamic goals in asymptomatic patients?

avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the overall hemodynamic goals in asymptomatic patients?. ### Response: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme.

What are the hemodynamic goals of elective noncardiac surgery?

avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the hemodynamic goals of elective noncardiac surgery?. ### Response: avoidance of both increased afterload and bradycardia by choosing the appropriate anesthetic scheme.

What are left-sided regurgitant lesions better tolerated than?

stenotic valvular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are left-sided regurgitant lesions better tolerated than?. ### Response: stenotic valvular disease.

What is stenotic valvular disease?

Left-sided regurgitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is stenotic valvular disease?. ### Response: Left-sided regurgitant lesions.

Patients with significant MR undergoing noncardiac surgery had higher rates of postoperative HF and myocardial infarction than did controls without MR?

11

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with significant MR undergoing noncardiac surgery had higher rates of postoperative HF and myocardial infarction than did controls without MR?. ### Response: 11.

What combination of neuraxial local anesthetics and opioids produces a favor able systemic vasodilation for patients with regurgitant valve lesions?

4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What combination of neuraxial local anesthetics and opioids produces a favor able systemic vasodilation for patients with regurgitant valve lesions?. ### Response: 4.

What does general anesthesia lower systemic vas-cular resistance?

Patients with regur -gitant lesions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does general anesthesia lower systemic vas-cular resistance?. ### Response: Patients with regur -gitant lesions.

What should be maintained for patients with regurgitant valve lesions?

preload

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be maintained for patients with regurgitant valve lesions?. ### Response: preload.

Invasive hemodynamic and/or intraoperative TEE monitoring allows for what?

continuous optimization of LV filling pressures and LV function during and after the opera-tive procedure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Invasive hemodynamic and/or intraoperative TEE monitoring allows for what?. ### Response: continuous optimization of LV filling pressures and LV function during and after the opera-tive procedure.

What should patients be admitted to an intensive monitoring setting for up to 24 to 72 hours after the procedure?

Invasive hemodynamic and/or intraoperative TEE monitoring

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients be admitted to an intensive monitoring setting for up to 24 to 72 hours after the procedure?. ### Response: Invasive hemodynamic and/or intraoperative TEE monitoring.

In functional MR, attention to afterload control and fluid balance should be given what?

careful

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In functional MR, attention to afterload control and fluid balance should be given what?. ### Response: careful.

What is a common cause of hemody-namic instability in patients with severe AR?

increased volume on myocardial wall stress

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a common cause of hemody-namic instability in patients with severe AR?. ### Response: increased volume on myocardial wall stress.

What is another term for ischemic heart disease and hypertrophic cardiomyopathy?

under -lying heart disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is another term for ischemic heart disease and hypertrophic cardiomyopathy?. ### Response: under -lying heart disease.

What may the perioperative stress associated with noncardiac surgery lead to?

hypotension, arrhythmias, HF, or even death

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may the perioperative stress associated with noncardiac surgery lead to?. ### Response: hypotension, arrhythmias, HF, or even death.

Patients with sig-nificant AR had a higher in-hospital mortality rate and higher mor-bidity rate?

noncardiac surgery

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Patients with sig-nificant AR had a higher in-hospital mortality rate and higher mor-bidity rate?. ### Response: noncardiac surgery.

What is the morbidity rate of postoperative myocardial infarction, stroke, pulmonary edema, intubation >24 hours, and major arrhythmias than case-matched controls without AR?

higher mor -bidity rate

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the morbidity rate of postoperative myocardial infarction, stroke, pulmonary edema, intubation >24 hours, and major arrhythmias than case-matched controls without AR?. ### Response: higher mor -bidity rate.

What is elevated serum creatinine >2 mg/dL?

Decreased LV systolic function

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is elevated serum creatinine >2 mg/dL?. ### Response: Decreased LV systolic function.

What are the 2018 Cholesterol Clinical Practice Guidelines8?

LIMITATIONS AND KNOWLEDGE GAPS

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the 2018 Cholesterol Clinical Practice Guidelines8?. ### Response: LIMITATIONS AND KNOWLEDGE GAPS.

What are ACC/AHA guidelines based largely on?

the outcomes of RCTs

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are ACC/AHA guidelines based largely on?. ### Response: the outcomes of RCTs.

What do RCTs of cholesterol-lowering thera-pies have established?

greater reductions of LDL-C are accompanied by greater reductions in risk of ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do RCTs of cholesterol-lowering thera-pies have established?. ### Response: greater reductions of LDL-C are accompanied by greater reductions in risk of ASCVD.

What are greater reductions of LDL-C accompanied by?

greater reductions in risk of ASCVD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are greater reductions of LDL-C accompanied by?. ### Response: greater reductions in risk of ASCVD.