prognosis/cardio-docs-qa · Datasets at Hugging Face

How many different int ensity categories are used for the purpose of his guideline?

3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many different int ensity categories are used for the purpose of his guideline?. ### Response: 3.

What is the per centage r eduction in lo w-density lipopr otein cholest erol they produce?

• low int ensity if t he reduction is 20% to 30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the per centage r eduction in lo w-density lipopr otein cholest erol they produce?. ### Response: • low int ensity if t he reduction is 20% to 30%.

What is low int ensity if the reduction is 20% to 30%?

medium int ensity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is low int ensity if the reduction is 20% to 30%?. ### Response: medium int ensity.

What is a high int ensity if t he reduction is abo ve 40%?

medium int ensity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a high int ensity if t he reduction is abo ve 40%?. ### Response: medium int ensity.

What is an appendix A for?

fur ther details

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an appendix A for?. ### Response: fur ther details.

What is a risk assessment and r eduction, including lipid modification?

Cardiovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a risk assessment and r eduction, including lipid modification?. ### Response: Cardiovascular disease.

What is the name of the book that discusses cardiovascular disease?

NICE 2023

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the name of the book that discusses cardiovascular disease?. ### Response: NICE 2023.

What is the last updat ed 10 F ebruar y 2023Page 6of 40?

Notice of right s

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the last updat ed 10 F ebruar y 2023Page 6of 40?. ### Response: Notice of right s.

How long after cath-eter ablation is stroke driven by discontinuation of oral anticoagulation?

3 months

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How long after cath-eter ablation is stroke driven by discontinuation of oral anticoagulation?. ### Response: 3 months.

What is the DOI for 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?

10.1161/CIR.0000000000000923 e178CLINICAL STATEMENTS AND GUIDELINESOtto

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the DOI for 2020 ACC/AHA Guideline for the Management of Valvular Heart Disease?. ### Response: 10.1161/CIR.0000000000000923 e178CLINICAL STATEMENTS AND GUIDELINESOtto.

What is driven chiefly by discontinuation of oral anticoagulation?

stroke

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is driven chiefly by discontinuation of oral anticoagulation?. ### Response: stroke.

Both US and European guideline statements on catheter ablation rec-ommend what?

anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Both US and European guideline statements on catheter ablation rec-ommend what?. ### Response: anticoagulation.

What should patients who have had surgical abla-tion be managed with?

at least 3 months of anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should patients who have had surgical abla-tion be managed with?. ### Response: at least 3 months of anticoagulation.

Who should be managed with at least 3 months of anticoagulation?

patients who have had surgical abla-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who should be managed with at least 3 months of anticoagulation?. ### Response: patients who have had surgical abla-tion.

What should be based on evaluation of arrhythmia recurrence in the context of their CHA2DS2-VASc score?

Subsequent anticoagulation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What should be based on evaluation of arrhythmia recurrence in the context of their CHA2DS2-VASc score?. ### Response: Subsequent anticoagulation.

What would be the preferred method of anticoagulation for the first 3 months?

VKA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What would be the preferred method of anticoagulation for the first 3 months?. ### Response: VKA.

What is a higher incidence of early AF in all patients after LA appendage occlusion/exclusion?

dem-onstrated

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a higher incidence of early AF in all patients after LA appendage occlusion/exclusion?. ### Response: dem-onstrated.

What has been dem-onstrated in patients after LA appendage occlusion/exclusion?

A higher incidence of early AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has been dem-onstrated in patients after LA appendage occlusion/exclusion?. ### Response: A higher incidence of early AF.

What is not recommended in patients with-out preexisting AF?

pre-emptive LA appendage occlusion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is not recommended in patients with-out preexisting AF?. ### Response: pre-emptive LA appendage occlusion.

No stroke benefit has been observed in this group of patients with no preemptive history of what?

AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: No stroke benefit has been observed in this group of patients with no preemptive history of what?. ### Response: AF.

What group of patients have no preemptive history of AF.15?

No stroke benefit has been observed in this group

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What group of patients have no preemptive history of AF.15?. ### Response: No stroke benefit has been observed in this group.

What is recommended for Diagnosis in Patients With VHD Undergoing Noncardiac Surgery?

COR LOE Recommendation1 C-EO1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is recommended for Diagnosis in Patients With VHD Undergoing Noncardiac Surgery?. ### Response: COR LOE Recommendation1 C-EO1.

In patients with clinical suspected moderate or greater degrees of what?

valvular stenosis or regurgitation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: In patients with clinical suspected moderate or greater degrees of what?. ### Response: valvular stenosis or regurgitation.

Preoperative echocardiography is recommended for patients with what type of stenosis or regurgitation?

valvular

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Preoperative echocardiography is recommended for patients with what type of stenosis or regurgitation?. ### Response: valvular.

What is the type of evaluation of patients with VHD who are undergoing noncardiac surgery dependent on?

the type

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the type of evaluation of patients with VHD who are undergoing noncardiac surgery dependent on?. ### Response: the type.

What indicates atrial fibrillation?

AF

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates atrial fibrillation?. ### Response: AF.

What indicates valvular heart disease?

VHD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What indicates valvular heart disease?. ### Response: VHD.

Who were recruited within the community?

those who were recruited within the community. For the outcome all -cause mortality

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Who were recruited within the community?. ### Response: those who were recruited within the community. For the outcome all -cause mortality.

How many studies were included for the outcome all -cause mortality?

1

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were included for the outcome all -cause mortality?. ### Response: 1.

What was the quality of the evidence?

very low

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the quality of the evidence?. ### Response: very low.

What did the outcome all-cause hospitalisations contain?

the same study

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the outcome all-cause hospitalisations contain?. ### Response: the same study.

What did a single study rated as very low quality show for the outcome QoL?

a clinically important improvement in QoL using both the MLWHF and KCCQ HRQoL scales

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a single study rated as very low quality show for the outcome QoL?. ### Response: a clinically important improvement in QoL using both the MLWHF and KCCQ HRQoL scales.

How many studies were rated as very low quality?

n=50

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many studies were rated as very low quality?. ### Response: n=50.

What scales showed a clinically important improvement in QoL?

MLWHF and KCCQ HRQoL

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What scales showed a clinically important improvement in QoL?. ### Response: MLWHF and KCCQ HRQoL.

What does smoking cessation reduce in mortality in smokers?

15% over 14 years

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does smoking cessation reduce in mortality in smokers?. ### Response: 15% over 14 years.

What is the definition of a body mass index 30 kg/m2?

obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the definition of a body mass index 30 kg/m2?. ### Response: obesity.

How much of the adult US population is obese?

≈30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the adult US population is obese?. ### Response: ≈30%.

How much of the adult US population falls into this category in recent years?

≈30%

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much of the adult US population falls into this category in recent years?. ### Response: ≈30%.

What is the positive rela-tionship between obesity and BP well documented?

39–

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the positive rela-tionship between obesity and BP well documented?. ### Response: 39–.

How much more likely are obese adults to be hypertensive compared with nonobese adults?

≈3 times

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How much more likely are obese adults to be hypertensive compared with nonobese adults?. ### Response: ≈3 times.

What may explain >60% of hypertension in adults?

increased adiposity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may explain >60% of hypertension in adults?. ### Response: increased adiposity.

What is considered a major risk factor for poor BP control in hypertensive patients?

obesity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is considered a major risk factor for poor BP control in hypertensive patients?. ### Response: obesity.

What is RAAS?

renin-angiotensin-aldosterone system

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is RAAS?. ### Response: renin-angiotensin-aldosterone system.

There is no acceptable guideline on the antihypertensive drug of choice for the management of hypertension among obese patients?

3

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There is no acceptable guideline on the antihypertensive drug of choice for the management of hypertension among obese patients?. ### Response: 3.

Why do investigators consider ACE inhibitors the drugs of choice?

their capacity to increase insulin sensitivity and thus reduce the risk of diabetes mellitus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do investigators consider ACE inhibitors the drugs of choice?. ### Response: their capacity to increase insulin sensitivity and thus reduce the risk of diabetes mellitus.

What does thiazide diuretics do in obesity-related hypertension?

lowering BP and improving cardiovascular out-comes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does thiazide diuretics do in obesity-related hypertension?. ### Response: lowering BP and improving cardiovascular out-comes.

What is the capacity of adequate BP control in obesity related hypertension?

lifestyle interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the capacity of adequate BP control in obesity related hypertension?. ### Response: lifestyle interventions.

Which drugs are associated with increased risk of diabetes mellitus?

thiazide diuretics

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Which drugs are associated with increased risk of diabetes mellitus?. ### Response: thiazide diuretics.

What is the efficacy of thiazide diuretics in lowering BP and improving cardiovascular out-comes in obese hypertensive patients?

well established

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the efficacy of thiazide diuretics in lowering BP and improving cardiovascular out-comes in obese hypertensive patients?. ### Response: well established.

-Blockers also have adverse effects on glucose metabolism but have led to significant improvement in what?

BP in obese

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: -Blockers also have adverse effects on glucose metabolism but have led to significant improvement in what?. ### Response: BP in obese.

What do -blockers decrease in obese patients?

renin activity

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do -blockers decrease in obese patients?. ### Response: renin activity.

What are renin activity and cardiac output often elevated in?

obese patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are renin activity and cardiac output often elevated in?. ### Response: obese patients.

Why is enthusiasm for the use of a blocker dampened by their negative profile on stroke outcomes?

placebo and other antihypertensive drug classes

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is enthusiasm for the use of a blocker dampened by their negative profile on stroke outcomes?. ### Response: placebo and other antihypertensive drug classes.

What are antihypertensive drug classes?

placebo

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are antihypertensive drug classes?. ### Response: placebo.

What is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control?

49There is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control among obese hypertensive patients

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control?. ### Response: 49There is abundant evidence in support of the effectiveness of lifestyle interventions in improving BP control among obese hypertensive patients.

What do adults need to do to lose weight?

identi-fying

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do adults need to do to lose weight?. ### Response: identi-fying.

What is the AHA/ACC guidelines docu-ment on?

lifestyle management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the AHA/ACC guidelines docu-ment on?. ### Response: lifestyle management.

What do AHA/ACC guidelines docu-ment on?

lifestyle management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What do AHA/ACC guidelines docu-ment on?. ### Response: lifestyle management.

What are the two main topics of the guidelines?

matching treatment benefits with risk profiles, diets for weight loss, lifestyle

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are the two main topics of the guidelines?. ### Response: matching treatment benefits with risk profiles, diets for weight loss, lifestyle.

What did the AHA publish in 2002?

“Unique Features of Infective Endocarditis in Childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did the AHA publish in 2002?. ### Response: “Unique Features of Infective Endocarditis in Childhood.

What was the focus of the 2002 AHA Scientific Statement?

Infective Endocarditis in Childhood

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the focus of the 2002 AHA Scientific Statement?. ### Response: Infective Endocarditis in Childhood.

When did other AHA reports focus on new recommendations for treatment of IE in adults?

20052

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did other AHA reports focus on new recommendations for treatment of IE in adults?. ### Response: 20052.

When did AHA report on major changes regarding IE prevention?

20073

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: When did AHA report on major changes regarding IE prevention?. ### Response: 20073.

What does this document update?

outpatient management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What does this document update?. ### Response: outpatient management.

How does IE affect infants and children?

specific atten-tion

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How does IE affect infants and children?. ### Response: specific atten-tion.

What is the impact of increased survival for children with congenital heart disease on the epidemiology of IE updated?

newer tools useful for diagnosis and treatment in the pediatric popula-tion are reviewed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the impact of increased survival for children with congenital heart disease on the epidemiology of IE updated?. ### Response: newer tools useful for diagnosis and treatment in the pediatric popula-tion are reviewed.

How are new tools useful for diagnosis and treatment in the pediatric popula-tion reviewed?

This review emphasizes changing manage-ment perspectives and discussion of new agents that have utility for treatment of resistant organisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How are new tools useful for diagnosis and treatment in the pediatric popula-tion reviewed?. ### Response: This review emphasizes changing manage-ment perspectives and discussion of new agents that have utility for treatment of resistant organisms.

What is the focus of this review?

changing manage-ment perspectives and discussion of new agents that have utility for treatment of resistant organisms

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the focus of this review?. ### Response: changing manage-ment perspectives and discussion of new agents that have utility for treatment of resistant organisms.

What is critical to the diagnosis and management of children with IE?

proper use of the diagnostic microbiology laboratory

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is critical to the diagnosis and management of children with IE?. ### Response: proper use of the diagnostic microbiology laboratory.

What has improved sensitivity and specificity for confirming the diagnosis of IE?

newer diag-nostic guidelines

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What has improved sensitivity and specificity for confirming the diagnosis of IE?. ### Response: newer diag-nostic guidelines.

Why is home intravenous therapy available?

improved infrastructure

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why is home intravenous therapy available?. ### Response: improved infrastructure.

What is an increasingly accepted approach for stable patients who are at low risk for complica-tions?

outpatient management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an increasingly accepted approach for stable patients who are at low risk for complica-tions?. ### Response: outpatient management.

What are stable patients who are at low risk for complica-tions?

outpatient management

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are stable patients who are at low risk for complica-tions?. ### Response: outpatient management.

Since the publication of the last AHA document on pediatric IE, what have the recommendations for prevention of IE been modified substantially?

pediatric cardiovascular concerns

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Since the publication of the last AHA document on pediatric IE, what have the recommendations for prevention of IE been modified substantially?. ### Response: pediatric cardiovascular concerns.

What are incorporated from the perspective of pediatric cardiovascular concerns?

the most current recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are incorporated from the perspective of pediatric cardiovascular concerns?. ### Response: the most current recommendations.

There are not likely to be any randomized con-trolled trials for treatment of what?

IE

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: There are not likely to be any randomized con-trolled trials for treatment of what?. ### Response: IE.

Many of the indications are based on what type of consensus?

consensus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Many of the indications are based on what type of consensus?. ### Response: consensus.

What are indications based on?

consensus

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are indications based on?. ### Response: consensus.

What was des-ignated as Class I indications?

interventions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was des-ignated as Class I indications?. ### Response: interventions.

Where the wording of treatments indicates a recommendation, what classification is used?

standard

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Where the wording of treatments indicates a recommendation, what classification is used?. ### Response: standard.

What classification system is used for recommendations?

ACC/AHA

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What classification system is used for recommendations?. ### Response: ACC/AHA.

What is the strength of the recommendation according to?

ACC/AHA classification system for recommendations

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the strength of the recommendation according to?. ### Response: ACC/AHA classification system for recommendations.

How often does IE occur in children?

less often

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How often does IE occur in children?. ### Response: less often.

How many pediatric admissions per year were there between 1972 and 1982?

1 in 1280

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pediatric admissions per year were there between 1972 and 1982?. ### Response: 1 in 1280.

What was the annual incidence rate in the United States between 2003 and 2010?

between approximately 0.05 and 0.12 cases per 1000 pediatric admissions

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What was the annual incidence rate in the United States between 2003 and 2010?. ### Response: between approximately 0.05 and 0.12 cases per 1000 pediatric admissions.

How many pediatric admissions were there between 2003 and 2010?

between approximately 0.05 and 0.12 cases per 1000

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: How many pediatric admissions were there between 2003 and 2010?. ### Response: between approximately 0.05 and 0.12 cases per 1000.

What is the reported hos-pitalization rates for IE?

vary considerably among published

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the reported hos-pitalization rates for IE?. ### Response: vary considerably among published.

What can be used to identify children who are at high risk of stroke and who benefit from transfusion therapy?

TCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What can be used to identify children who are at high risk of stroke and who benefit from transfusion therapy?. ### Response: TCD.

What remains the most extensively validated method for risk assessment?

TCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What remains the most extensively validated method for risk assessment?. ### Response: TCD.

What is an extensively validated method for risk assessment?

TCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is an extensively validated method for risk assessment?. ### Response: TCD.

What are some additional predictors that may come from incorporating?

anterior cerebral artery velocity, blood biomarkers, variations in several genes, and nocturnal oxygen saturation

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What are some additional predictors that may come from incorporating?. ### Response: anterior cerebral artery velocity, blood biomarkers, variations in several genes, and nocturnal oxygen saturation.

On the basis of STOP II, even those whose risk of stroke decreases with transfusion therapy decreases?

≈50% probability of reverting to high risk or having a stroke if transfusion therapy is discontinued

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: On the basis of STOP II, even those whose risk of stroke decreases with transfusion therapy decreases?. ### Response: ≈50% probability of reverting to high risk or having a stroke if transfusion therapy is discontinued.

What is the risk of stroke that decreases with transfusion therapy?

≈50% probability of reverting to high risk

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of stroke that decreases with transfusion therapy?. ### Response: ≈50% probability of reverting to high risk.

What is a 50% probability of reverting to high risk or having a stroke if transfusion is discontinued?

≈

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is a 50% probability of reverting to high risk or having a stroke if transfusion is discontinued?. ### Response: ≈.

Why do studies show the need for ongoing active treatment despite TCD normaliza-tion and the risk of iron toxicity with repeated transfusions?

Alternative methods of maintenance therapy that are safer than transfusion need to be developed

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Why do studies show the need for ongoing active treatment despite TCD normaliza-tion and the risk of iron toxicity with repeated transfusions?. ### Response: Alternative methods of maintenance therapy that are safer than transfusion need to be developed.

Predictive methods other than TCD (eg, MRI techniques) need to be systematically compared and combined with what?

TCD

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Predictive methods other than TCD (eg, MRI techniques) need to be systematically compared and combined with what?. ### Response: TCD.

What may be beneficial when red cell transfusions are downloaded from http://ahajournals.org by on April 28, 2023?

Hydroxyurea

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What may be beneficial when red cell transfusions are downloaded from http://ahajournals.org by on April 28, 2023?. ### Response: Hydroxyurea.

What is the risk of recurrence of hyper tensi ve disorders of pregnanc y and long-term c ardiovascular dise ase?

Risk o f recurr ence of hyper tensi ve disor ders of pregnanc y and long-term c ardiovascular dise ase Recommendations 1 .10.1 to 1.10.4

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What is the risk of recurrence of hyper tensi ve disorders of pregnanc y and long-term c ardiovascular dise ase?. ### Response: Risk o f recurr ence of hyper tensi ve disor ders of pregnanc y and long-term c ardiovascular dise ase Recommendations 1 .10.1 to 1.10.4.

Long-t erm f ollow-up studies of w omen who ha ve experienced h yper tensiv e disor ders during pr egnancy sho wed an incr eased risk of what?

long-t erm car diovascular disease

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: Long-t erm f ollow-up studies of w omen who ha ve experienced h yper tensiv e disor ders during pr egnancy sho wed an incr eased risk of what?. ### Response: long-t erm car diovascular disease.

What did a higher pr evalence of h yper tensiv e disor ders compare with women unaff ected with?

hyper tensiv e disor ders

Below is an instruction that describes a task. Write a response that appropriately completes the request. ### Instruction: What did a higher pr evalence of h yper tensiv e disor ders compare with women unaff ected with?. ### Response: hyper tensiv e disor ders.