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The early Queen logo resembled the coat of arms of what country?
United Kingdom
45,152
When did more commercial streets become built in Nanjing?
In the past 20 years
17,092
Kathmandu resulted from the merger of what two settlements?
Dakshin Koligram
87,358
What century saw the end of the Middle Ages?
15th
23,253
In attempting to take back control, George III and George IV opposed which church movement?
Catholic Emancipation
62,445
Who brought Christian missionaries to Hawaii?
traders
36,339
What shows God is not omnipotent if he creates a stone that he cannot lift?
there is something that he cannot do
63,405
How many are believed to have been uprooted by this unrest ?
It displaced more than 52,000 people
47,600
What amount of Swazi Christians are Roman Catholic?
20%
80,365
What thus is the level of economic incentive and benefit?
minimal
87,239
Where were idioms and vocabulary imported from?
source languages
80,484
What causes Schwannomatosis ?
What causes schwannomatosis? Some cases of schwannomatosis are caused by changes (mutations) in the SMARCB1 or LZTR1 genes. SMARCB1 and LZTR1 are tumor suppressor genes, which means that they encode a protein that stops cells from growing and dividing too rapidly or in an uncontrolled way. Mutations in these genes result in abnormal proteins that are unable to carry out their normal roles. This contributes to the development of the many different types of tumors found in schwannomatosis. When schwannomatosis is caused by a mutation in SMARCB1 or LZTR1, the affected person is typically born with one mutated copy of the gene in each cell and is, therefore, genetically predisposed to develop the tumors associated with the condition. For a tumor to form, two copies of the gene must be altered. The mutation in the second copy of the gene is considered a somatic mutation because it occurs during a person's lifetime and is not inherited. In affected people without a mutation in SMARCB1 or LZTR1, the underlying cause of the condition is unknown.
113,040
Who was the English politician who appeased Germany with the take over of Czechoslovakia
Chamberlain
53,477
What are the treatments for Melnick-Needles syndrome ?
These resources address the diagnosis or management of Melnick-Needles syndrome: - Gene Review: Gene Review: Otopalatodigital Spectrum Disorders - Genetic Testing Registry: Melnick-Needles syndrome These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
106,690
Which street is much wider from Avenue C to First Avenue?
20th Street
21,523
Where did Islamic influence in Tibet come from?
Persia
60,320
What caused the decrease in commerce and production in the 14th century?
demographic crisis
49,211
What was previously located at the present location of Forest Hill Park?
Forest Hill Amusement Park
78,884
Which Atlantic City neighborhood became particularly impoverished in the mid-to-late 20th century?
the "Inlet"
25,155
What is the lowland area of Tennessee between the Tennessee River and Mississippi River called?
Tennessee Bottoms
69,684
Who does the Kindlifresserbrunnen scare?
disobedient children.
17,268
How many mens' rhythmic gymnasts were in Japan in 2002?
1000
28,053
What part of the name is always capitalized?
the genus
46,449
What to do for Primary Biliary Cirrhosis ?
- Primary biliary cirrhosis is a chronic disease that causes the small bile ducts in the liver to become inflamed and damaged and ultimately disappear. - When chronic inflammation damages the bile ducts, bile and toxic wastes build up in the liver, damaging liver tissue. This damage to the liver tissue can lead to cirrhosis. - The causes of primary biliary cirrhosis are unknown. Most research suggests it is an autoimmune disease. - Primary biliary cirrhosis is more common in people who have a parent or siblingparticularly an identical twinwith the disease. - The first and most common symptoms of primary biliary cirrhosis are fatigue, itching, and dry eyes and mouth. Some people may have jaundice, a condition that causes the skin and whites of the eyes to turn yellow. Health care providers diagnose up to 60 percent of people with primary biliary cirrhosis before symptoms begin. - Most complications of primary biliary cirrhosis are related to cirrhosis and start after primary biliary cirrhosis progresses to cirrhosis. - A health care provider may use the following tests to diagnose primary biliary cirrhosis: - a medical and family history - a physical exam - blood tests - imaging tests - a liver biopsy - Health care providers prescribe ursodiol (Actigall, Urso) to treat primary biliary cirrhosis. Early treatment with this medication reduces the likelihood of needing a liver transplant and improves survival. - A health care provider may consider a liver transplant when cirrhosis leads to liver failure or treatment for complications is ineffective.
120,324
What to do for What I need to know about Crohn's Disease ?
Your health care provider may start you on a special diet, so you get extra nutrition and calories. High-calorie liquid supplements are often used to give you the extra calories and right amount of vitamins and minerals to keep you healthy. During acute phases of the disease, you may need to receive intravenous nutrition to give the intestine a rest. No foods are known to cause injury or inflammation to the intestine. But foods such as hot spices, alcohol, greasy foods, and milk products may make diarrhea and cramping worse. You should eat a healthy diet and avoid foods that make symptoms worse. Your health care provider may refer you to a dietitian to help you with meal planning.
88,972
What trees are typically found in the dryer portions?
oak
67,322
On what date was a state funeral held for Napoleon?
15 December 1840
39,207
What did Lodygin change his name to after moving to the USA?
Alexander de Lodyguine
40,842
For what length of time can a dead lower limb stay attached to a tree?
years
22,657
Who was the last pope to be crowned?
Paul VI
50,432
What showed that aircraft could be a significant contribution to the battlefield?
World War I
32,178
Is trird rail system being used exclusively with AC or DC ?
DC distribution
72,094
What school serves as the largest employer of New Haven?
Yale University
44,155
what research (or clinical trials) is being done for Dystonias ?
The National Institute of Neurological Disorders and Stroke (NINDS) conducts research related to dystonia in its laboratories at the National Institutes of Health (NIH) and also supports additional dystonia research through grants to major research institutions across the country. Scientists at other NIH Institutes (National institute on Deafness and Other Communications Disorders, National Eye Institute, and Eunice Kennnedy Shriver National Institute on Child Health and Human Development) also support research that may benefit individuals with dystonia. Investigators believe that the dystonias result from an abnormality in an area of the brain called the basal ganglia, where some of the messages that initiate muscle contractions are processed. Scientists at the NINDS laboratories have conducted detailed investigations of the pattern of muscle activity in persons with dystonias. Studies using EEG analysis and neuroimaging are probing brain activity. The search for the gene or genes responsible for some forms of dominantly inherited dystonias continues.
87,884
Who was elected in 1946 as the first representative?
Barthélémy Boganda
62,725
What has Ric Flair accomplished?
multiple world heavyweight championship reigns spanning over three decades
43,063
Other than Protestantism, what are the other two divisions of Christianity?
Roman Catholicism and Eastern Orthodoxy
84,504
Who used Gothic details in construction of Tom Tower, Oxford?
Christopher Wren
49,579
What group is briging ligands most common in?
group 13
14,603
Which two types of antibiotics target the cell wall?
penicillins and cephalosporins
1,330
What causes Dry Mouth ?
Dry mouth can cause several problems, including difficulty tasting, chewing, swallowing, and speaking. Swallowing may be especially difficult for those with too little saliva. For example, people with dry mouth may be unable to swallow dry food at all unless they also drink fluids with food. They also need to take small bites of food and be very aware of chewing and swallowing so they don't choke. Dry mouth may also increase the chance of developing dental decay as well as oral fungal infections such as thrush, which causes painful white patches in the mouth.
91,174
What are the symptoms of Diabetic Retinopathy ?
At first, you will see a few specks of blood, or spots, "floating" in your vision. If spots occur, see your eye care professional as soon as possible. You may need treatment before more serious bleeding or hemorrhaging occurs. Hemorrhages tend to happen more than once, often during sleep. Sometimes, the spots clear without treatment, and you will see better. However, bleeding can reoccur and cause severely blurred vision. You need to be examined by your eye care professional at the first sign of blurred vision, before more bleeding occurs. If left untreated, proliferative retinopathy can cause severe vision loss and even blindness. Also, the earlier you receive treatment, the more likely treatment will be effective.
118,274
Who introduced educative gymnastics in France?
Don Francisco Amorós y Ondeano
28,034
What is solar energy's yearly potential?
1,575–49,837 exajoules (EJ)
5,070
Which two areas were slowly Germanized during the 13th century?
Old-Prussian (north) and Polish (south) toponyms
67,461
What causes Dry Mouth ?
Dry mouth can cause several problems, including difficulty tasting, chewing, swallowing, and speaking. Swallowing may be especially difficult for those with too little saliva. For example, people with dry mouth may be unable to swallow dry food at all unless they also drink fluids with food. They also need to take small bites of food and be very aware of chewing and swallowing so they don't choke. Dry mouth may also increase the chance of developing dental decay as well as oral fungal infections such as thrush, which causes painful white patches in the mouth.
118,941
What classic area of study is now mostly reserved for academic consideration?
Philosophy
52,293
Who is at risk for Overweight and Obesity? ?
Overweight and obesity affect Americans of all ages, sexes, and racial/ethnic groups. This serious health problem has been growing over the last 30 years. Adults According to the National Health and Nutrition Examination Survey (NHANES) 20092010, almost 70 percent of Americans are overweight or obese. The survey also shows differences in overweight and obesity among racial/ethnic groups. In women, overweight and obesity are highest among non-Hispanic Black women (about 82percent), compared with about 76 percent for Hispanic women and 64 percent for non-Hispanic White women. In men, overweight and obesity are highest among Hispanic men (about 82percent), compared with about 74 percent for non-Hispanic White men and about 70 percent for non-Hispanic Black men. Children and Teens Children also have become heavier. In the past 30 years, obesity has tripled among school-aged children and teens. According to NHANES 20092010, about 1 in 6 American children ages 219 are obese. The survey also suggests that overweight and obesity are having a greater effect on minority groups, including Blacks and Hispanics.
91,693
What sort of techniques did the State Department conclude were still being employed by China?
coercive techniques
13,205
How long have railroads been important since in Montana
1880s
1,070
How many people are affected by spinal muscular atrophy ?
Spinal muscular atrophy affects 1 in 6,000 to 1 in 10,000 people.
105,897
Is DICER1 syndrome inherited ?
DICER1 syndrome is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to cause the disorder. It is important to note that people inherit an increased risk of tumors; many people who have mutations in the DICER1 gene do not develop abnormal growths.
107,629
Who did Bush feel was important to remove from power, after removing the Taliban from Kabul?
Saddam Hussein
65,887
How much of Houston's population is white?
51%
26,554
What is the general opinion of the difficulty level of Whitehead's work in philosophy?
generally considered to be among the most difficult to understand in all of the western canon
8,842
When did many former colonies' citizens begin immigrating into Britain?
after the Second World War
46,234
What was the title of the first book printed in France?
Epistolae
65,561
Where is the neural connection that is active during migration located?
between the eye and "Cluster N"
25,026
Bicycling magazine named Boston one of the worst cities in the US for what?
cycling
15,159
In a Hindu funeral, who is typically the main mourner?
first son
87,558
How many people are affected by congenital fibrosis of the extraocular muscles ?
CFEOM1 is the most common form of congenital fibrosis of the extraocular muscles, affecting at least 1 in 230,000 people. CFEOM1 and CFEOM3 have been reported worldwide, whereas CFEOM2 has been seen in only a few families of Turkish, Saudi Arabian, and Iranian descent. Tukel syndrome appears to be very rare; it has been diagnosed in only one large Turkish family.
94,833
How many regional health administrations exist in Portugal?
Five
5,847
Who traded slaves into the Middle East?
Arabs
21,231
Where did Kanye first speak on his mother's death?
New Zealand
6,272
In Parliament, who was the leader of the monarchists?
Adolphe Thiers
33,104
How to diagnose Deep Vein Thrombosis ?
Your doctor will diagnose deep vein thrombosis (DVT) based on your medical history, a physical exam, and test results. He or she will identify your risk factors and rule out other causes of your symptoms. For some people, DVT might not be diagnosed until after they receive emergency treatment for pulmonary embolism (PE). Medical History To learn about your medical history, your doctor may ask about: Your overall health Any prescription medicines you're taking Any recent surgeries or injuries you've had Whether you've been treated for cancer Physical Exam Your doctor will check your legs for signs of DVT, such as swelling or redness. He or she also will check your blood pressure and your heart and lungs. Diagnostic Tests Your doctor may recommend tests to find out whether you have DVT. Common Tests The most common test for diagnosing deep vein blood clots is ultrasound. This test uses sound waves to create pictures of blood flowing through the arteries and veins in the affected leg. Your doctor also may recommend a D-dimer test or venography (ve-NOG-rah-fee). A D-dimer test measures a substance in the blood that's released when a blood clot dissolves. If the test shows high levels of the substance, you may have a deep vein blood clot. If your test results are normal and you have few risk factors, DVT isn't likely. Your doctor may suggest venography if an ultrasound doesn't provide a clear diagnosis. For venography, dye is injected into a vein in the affected leg. The dye makes the vein visible on an x-ray image. The x ray will show whether blood flow is slow in the vein, which may suggest a blood clot. Other Tests Other tests used to diagnose DVT include magnetic resonance imaging (MRI) and computed tomography (to-MOG-rah-fee), or CT, scanning. These tests create pictures of your organs and tissues. You may need blood tests to check whether you have an inherited blood clotting disorder that can cause DVT. This may be the case if you have repeated blood clots that are not related to another cause. Blood clots in an unusual location (such as the liver, kidney, or brain) also may suggest an inherited clotting disorder. If your doctor thinks that you have PE, he or she may recommend more tests, such as a lung ventilation perfusion scan (VQ scan). A lung VQ scan shows how well oxygen and blood are flowing to all areas of the lungs. For more information about diagnosing PE, go to the Health Topics Pulmonary Embolism article.
117,039
What is (are) Tetralogy of Fallot ?
Tetralogy of Fallot is a complex congenital heart defect characterized by a large ventricular septal defect (hole between the right and left ventricles), pulmonary stenosis (narrowing of the valve and artery that connect the heart with the lungs), an overriding aorta (the aorta - the artery that carries oxygen-rich blood to the body - is shifted over the right ventricle and ventricular septal defect, instead of coming out only from the left ventricle), and right ventricular hypertrophy (the muscle of the right ventricle is thicker than usual). Tetralogy of Fallot causes low oxygen levels in the blood, which can lead to cyanosis (a bluish-purple color to the skin). The cause of this condition is unknown. Treatment involves surgery to repair the heart defects. Sometimes more than one surgery is needed.
114,689
The Austro-Turkish war took place over what years?
1716–1718
67,629
When siblings act as peers, what positive effects are possible?
increase one another's sociability and feelings of self-worth
30,896
What system deemed non-Muslims subjects of the empire but unbound by Muslim law?
the millet system
67,805
Do you have information about CPR
Summary : When someone's blood flow or breathing stops, seconds count. Permanent brain damage or death can happen quickly. If you know how to perform cardiopulmonary resuscitation (CPR), you could save a life. CPR is an emergency procedure for a person whose heart has stopped or is no longer breathing. CPR can maintain circulation and breathing until emergency medical help arrives. Even if you haven't had training, you can do "hands-only" CPR for a teen or adult whose heart has stopped beating ("hands-only" CPR isn't recommended for children). "Hands-only" CPR uses chest compressions to keep blood circulating until emergency help arrives. If you've had training, you can use chest compressions, clear the airway, and do rescue breathing. Rescue breathing helps get oxygen to the lungs for a person who has stopped breathing. To keep your skills up, you should repeat the training every two years.
92,375
Is leptin receptor deficiency inherited ?
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
109,064
What are the genetic changes related to familial exudative vitreoretinopathy ?
Mutations in the FZD4, LRP5, and NDP genes can cause familial exudative vitreoretinopathy. These genes provide instructions for making proteins that participate in a chemical signaling pathway that affects the way cells and tissues develop. In particular, the proteins produced from the FZD4, LRP5, and NDP genes appear to play critical roles in the specialization of retinal cells and the establishment of a blood supply to the retina and the inner ear. The LRP5 protein also helps regulate bone formation. Mutations in the FZD4, LRP5, or NDP gene disrupt chemical signaling during early development, which interferes with the formation of blood vessels at the edges of the retina. The resulting abnormal blood supply to this tissue leads to retinal damage and vision loss in some people with familial exudative vitreoretinopathy. The eye abnormalities associated with familial exudative vitreoretinopathy tend to be similar no matter which gene is altered. However, affected individuals with LRP5 gene mutations often have reduced bone mineral density in addition to vision loss. Mutations in the other genes responsible for familial exudative vitreoretinopathy do not appear to affect bone density. In some cases, the cause of familial exudative vitreoretinopathy is unknown. Researchers believe that mutations in several as-yet-unidentified genes are responsible for the disorder in these cases.
95,974
Who did Gaius Cassius and Marcus Brutus lead the conspiracy against?
Caesar
78,093
If a place has annual seasons, what are the growth rings on the trees there called?
annual rings
22,641
What are the treatments for Primary Sclerosing Cholangitis ?
Although researchers have studied many treatments, none has been shown to cure or slow the progress of PSC. Treatment of PSC aims to relieve symptoms and manage complications. Medical treatment may include various medications to relieve itching, antibiotics to treat infections, and vitamin supplements. Instruments passed through an endoscope during ERCP can help open blocked bile ducts. Liver transplantation may be an option if the liver begins to fail.
89,878
What were the men and women sent to the eastern front against their will called?
Malgré-nous
60,540
Along with Jama Korshel, who led the Supreme Revolutionary Council?
Salaad Gabeyre Kediye
23,029
When was the system of coroners first introduced?
1194
31,743
What needs to stay away from loopholes?
national anti-corruption initiatives
18,097
What are the symptoms of Chondrodysplasia, Grebe type ?
What are the signs and symptoms of Chondrodysplasia, Grebe type? The Human Phenotype Ontology provides the following list of signs and symptoms for Chondrodysplasia, Grebe type. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Abnormality of the metacarpal bones 90% Adactyly 90% Bowing of the long bones 90% Brachydactyly syndrome 90% Limitation of joint mobility 90% Micromelia 90% Short stature 90% Short toe 90% Skeletal dysplasia 90% Synostosis of carpal bones 90% Tarsal synostosis 90% Abnormality of the fibula 50% Abnormality of the tibia 50% Aplasia/Hypoplasia of the thumb 50% Postaxial hand polydactyly 50% Acromesomelia - Aplasia/Hypoplasia involving the metacarpal bones - Aplasia/Hypoplasia of metatarsal bones - Aplasia/Hypoplasia of the patella - Autosomal recessive inheritance - Death in infancy - Disproportionate short-limb short stature - Fibular hypoplasia - Flexion contracture - Hypoplasia of the radius - Hypoplasia of the ulna - Short digit - Short femur - Short foot - Short humerus - Short phalanx of finger - Short tibia - Stillbirth - Valgus foot deformity - Valgus hand deformity - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
112,200
Under whose reign did Nabatean culture begin to show Greek influence?
Aretas III Philhellene
38,670
What are the symptoms of Ainhum ?
What are the signs and symptoms of Ainhum? The Human Phenotype Ontology provides the following list of signs and symptoms for Ainhum. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Amniotic constriction ring - Autosomal dominant inheritance - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
109,817
How many deaths were reported only in the Sichuan province?
68,636
3,442
Do you have information about Hormone Replacement Therapy
Summary : Menopause is the time in a woman's life when her period stops. It is a normal part of aging. In the years before and during menopause, the levels of female hormones can go up and down. This can cause symptoms such as hot flashes and vaginal dryness. Some women take hormone replacement therapy (HRT), also called menopausal hormone therapy, to relieve these symptoms. HRT may also protect against osteoporosis. However, HRT also has risks. It can increase your risk of breast cancer, heart disease, and stroke. Certain types of HRT have a higher risk, and each woman's own risks can vary depending upon her health history and lifestyle. You and your health care provider need to discuss the risks and benefits for you. If you do decide to take HRT, it should be the lowest dose that helps and for the shortest time needed. Taking hormones should be re-evaluated every six months. NIH: National Heart, Lung, and Blood Institute
117,756
What years did the Rinpungpa regime start and end?
1435–1565
2,316
When Napoleon reached Donauwörth, how much distance were the wings of the Grande Armée separated by?
75 miles (121 km)
39,124
What specifically how does Louis' Lunch cooks its' food?
1898 cast iron stoves using gridirons
44,203
What are the treatments for deoxyguanosine kinase deficiency ?
These resources address the diagnosis or management of deoxyguanosine kinase deficiency: - Gene Review: Gene Review: DGUOK-Related Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form - Genetic Testing Registry: Mitochondrial DNA-depletion syndrome 3, hepatocerebral - MedlinePlus Encyclopedia: Hypotonia These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
107,950
On January 25, 1918, what was the official name given to the Soviet state?
the Soviet Russian Republic
13,287
What is (are) Acinetobacter in Healthcare Settings ?
Acinetobacter [asz−in−ée−toe–back−ter] is a group of bacteria commonly found in soil and water. While there are many types or “species” of Acinetobacter and all can cause human disease, Acinetobacter baumannii [asz−in−ée−toe–back−ter boe-maa-nee-ie] accounts for about 80% of reported infections. Outbreaks of Acinetobacter infections typically occur in intensive care units and healthcare settings housing very ill patients. Acinetobacter infections rarely occur outside of healthcare settings.
87,827
What is the outlook for Hydromyelia ?
Surgery may permanently or temporarily relieve symptoms, but it can also cause a number of severe complications. In rare cases, hydromyelia may resolve on its own without any medical intervention.
115,731
What pharmaceutical company serves as a large employment provider for New Haven?
Alexion
44,068
What are the treatments for pulmonary arterial hypertension ?
These resources address the diagnosis or management of pulmonary arterial hypertension: - Gene Review: Gene Review: Heritable Pulmonary Arterial Hypertension - Genetic Testing Registry: Primary pulmonary hypertension - Genetic Testing Registry: Primary pulmonary hypertension 2 - Genetic Testing Registry: Primary pulmonary hypertension 3 - Genetic Testing Registry: Primary pulmonary hypertension 4 - MedlinePlus Encyclopedia: Pulmonary hypertension These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
107,015
What does Sperling claim did not have any control over Tibet?
China's intervening Ming dynasty
2,390
What does the Duchy of Lancaster operate as?
a property company
29,065
What does EYS stand for?
Expected years of schooling
11,022
How many additional actors were needed for the shoot in Mexico City?
1,500
3,168
What album did Kanye receive production credits on in 2001?
The Blueprint
5,970
What is the probability of molecule to have energy greater than or equal to E at the given temperature T?
e−E/kT
67,371