json
dict | jpg
imagewidth (px) 49
4.1k
| __key__
stringlengths 6
6
| __url__
stringclasses 29
values |
|---|---|---|---|
{
"caption": "(a) Photographs of select whale and artiodactyl skulls, highlighting the region with observed lateral palatal foramina. (b) Close up photographs highlighting the morphology of the lateral palatal foramina. White brackets surround lateral palatal foramina and their associated sulci. Teeth or their corresponding alveoli are labeled as Incisors (I), premolars (P), or molars (M). (c) Generalized phylogenetic tree illustrating the relationships of the taxa pictured above.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259611-3-41598_2022_15684_Fig4_HTML.jpg"
} | 009300 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Performance of endoscopic lumbar sympathectomy. (a) The patient was lying down in supine position during the surgical procedure under general anesthesia. Three trocars were inserted on the lateral abdominal wall between the rib cage and hip bone. (b) A probe of laser doppler flowmetry was attached on the center of each sole of the patient by a holder using double-sided adhesive tape.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259612-0-41598_2022_14778_Fig1_HTML.jpg"
} | 009301 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Fluorescence confocal microscopy of proteinosomes.a Dual colour fluorescence confocal images of proteinosomes containing template DNA (protein conjugate labelled with fluorescein isothiocyanate (FITC) and DNA complex labelled with carboxy-X-rhodamine (ROX), b Zoom in of single proteinosome from: (i) Dual colour fluorescence, (ii) Single colour fluorescence channel, DNA labelled with ROX, (iii) protein conjugate labelled with FITC. All scale bars are 25 μm. c Fluorescent confocal microscopy images of photobleaching experiments, output frames for dual fluorescence confocal images of DNA-biotin-streptavidin complex labelled with ROX and protein conjugate labelled with FITC at t = 0 s (before bleaching), t = 160 s (after bleaching) and t = 680 s (after bleaching). Dotted rectangles show the region of photobleaching. All scale bars are 25 μm. Data are representative from at least 10 repeats. d Characterisation of the permeability of DNA (i) and PEN enzymes (ii) into proteinosomes. d (i) Bright-field image (t = 0 s) used to locate proteinosomes at t = 0 s. Output frames from Fluorescence Recovery after Photobleaching (FRAP) experiments of (i) single-stranded DNA (labelled with DY530) at t = 0 s (before photobleaching), t = 8.4 s (immediately after photobleaching) and t = 30 s (after recovery). Representation from two repeats. Scale bars are 20 μm. (ii) Polymerase enzyme tagged with FITC. Output frames at t = 0 s (before photobleaching), t = 0.4 s and t = 6.8 s and t = 600 s (after recovery). Scale bar is 20 μm. Dotted circle indicates bleached spot and the non-dotted circles show backgrounds used for normalisation from a single experiment. e FRAP analysis of (i) single-stranded DNA (ii) polymerase. Source data are provided in the source data file.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259615-3-41467_2022_31471_Fig2_HTML.jpg"
} | 009302 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Overview of G. bimaculatus blastoderm formation and evidence that nuclei move actively, rather than being moved passively by flowing cytoplasm.a Time points from the embryonic syncytial development of G. bimaculatus, displayed as \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$$z$$\\end{document}z-projections of 3D stacks. Micrographs are from an H2B-EGFP transgenic G. bimaculatus embryo live-imaged using a lightsheet microscope over eight hours of development at 28.5 °C, capturing nuclear divisions and movements throughout the syncytial embryo. The nuclei (n) arrange into a single layer, after which cellularization occurs and the embryonic rudiment forms. Embryos are oriented laterally with ventral to the bottom and anterior to the left. Anterior is to the left in all subsequent figures. Embryonic stage (ES) and egg stage (EgS) are indicated for each time point33. b Nuclei were tracked to produce a 3D + T dataset of nuclear lineages. All nuclear tracks are displayed for an example embryo, with the lineage descended from a single nucleus highlighted. Color scale represents time; n = number of nuclei. Black arrowhead highlights nuclei that move in a highly directed manner toward the anterior pole. c Example time points from a 3D + T dataset of a transgenic G. bimaculatus embryo with nuclei and cytoplasm fluorescently marked (further details in Methods). Left column shows the nucleus channel, and the right column shows the cytoplasm channel, with the energid cytoplasm highlighted in magenta and the nucleus highlighted in cyan. White arrowheads mark two putative yolk granules that remain in place as the nucleus moves past them. d Pairwise correlations between the instantaneous movement vectors of pairs of non-sister nuclei. White line indicates median, box indicates 25th−75th percentiles, whiskers show range. Source data are provided as a Source Data file.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259616-4-41467_2022_31212_Fig1_HTML.jpg"
} | 009303 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Impact of sampling patterns on the reconstruction performance of the magnitude images. (a) CL = 23 \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$${\\sigma }_{y}$$\\end{document}σy = 0, (b) CL = 7 \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$${\\sigma }_{y}$$\\end{document}σy = 0.10, (c) CL = 7 \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$${\\sigma }_{y}$$\\end{document}σy = 0.15 and (d) CL = 7 \\documentclass[12pt]{minimal}\n\t\t\t\t\\usepackage{amsmath}\n\t\t\t\t\\usepackage{wasysym} \n\t\t\t\t\\usepackage{amsfonts} \n\t\t\t\t\\usepackage{amssymb} \n\t\t\t\t\\usepackage{amsbsy}\n\t\t\t\t\\usepackage{mathrsfs}\n\t\t\t\t\\usepackage{upgreek}\n\t\t\t\t\\setlength{\\oddsidemargin}{-69pt}\n\t\t\t\t\\begin{document}$${\\sigma }_{y}$$\\end{document}σy = 0.20. Acceleration rate = 5. Although the model succeeded in fully removing local artifacts in the background, red arrows show examples of local artifacts still present inside the ROIs.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259619-1-41598_2022_14039_Fig4_HTML.jpg"
} | 009304 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOM expression in the olfactory epithelium. Confocal micrographs at high magnification of coronal sections of the olfactory epithelium of WT (a–c), Triple KO (d–f), and Stoml3 KO (g–i) mice, double-stained with anti-STOM (red) and anti-OMP (green) antibodies. In WT mice, STOM mainly localizes in the knob/ciliary region of the OSNs while in the cell body it is detected in puncta (a–c). STOM staining is not present in triple KO mice, confirming the specificity of the signal observed in WT (d–f). In Stoml3 KO mice, STOM is absent in the ciliary layer, and in some OSNs it remains trapped in their dendrites and knobs (g–i). Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-0-41598_2022_15572_Fig3_HTML.jpg"
} | 009305 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOM expression in the olfactory bulb. Confocal micrographs of coronal sections of the OB of WT (a–c), triple KO (d–f), and Stoml3 KO (g–i) mice, double-stained with anti-STOM (red) and anti-OMP (in green) antibodies. In WT mice, STOM is not detected in the OB. Triple KO (d–f) mice do not display any staining with anti-STOM antibodies. In contrast, in Stoml3 KO mice, STOM strongly mis-localizes in the glomeruli (g–i). Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-1-41598_2022_15572_Fig4_HTML.jpg"
} | 009306 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Stomatin-domain protein localization in olfactory areas of the nasal cavity. Confocal micrographs at low magnification of coronal sections of the OE of WT mice immuno-stained with antibodies (red) against STOM (a), STOML1 (b), STOML2 (c), and STOML3 (d). The same sections were double-stained with anti-OMP antibodies (e–h, green). At low magnification, STOML2 is mainly visible around the axon bundles of the OSNs, while STOML1 is detected in the cartilage of the nasal septum. STOM and STOML3 predominantly localize in the apical part of the OE along the interface with the lumen of the nasal cavity. Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-2-41598_2022_15572_Fig2_HTML.jpg"
} | 009307 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOML1 is expressed in the cell body of olfactory sensory neurons. Confocal micrographs at high magnification of coronal sections of the olfactory epithelium of WT (a–c), triple KO (d–f), and Stoml3 KO (g–i) mice, double-stained with anti-STOML1 (red) and anti-OMP (green) antibodies. In WT mice, STOML1 localizes in the cell body of the OSNs (a–c) and same pattern is observed in Stoml3 KO (g–i). STOML1 is not detected in triple KO mice (d–f Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-3-41598_2022_15572_Fig5_HTML.jpg"
} | 009308 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOML2 is expressed in olfactory sensory neurons, basal stem cells and ensheathing cells. Confocal micrographs at high magnification of coronal sections of the OE of WT (a–c), triple KO (g–i) and Stoml3 KO (j–l) mice, double-stained with anti-STOML2 (red) and anti-OMP (green) antibodies. In all the three mice models, STOML2 has a punctate pattern spread throughout the OE. STOML2 is detected in the soma of the OSNs, although it is almost absent in the ciliary layer. STOML2 signal also is observed in the most basal region of the OE where locate the basal stem cells. (d–f) Higher magnification of OSN axon bundles shows the localization of STOML2 in ensheathing cells. Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-4-41598_2022_15572_Fig6_HTML.jpg"
} | 009309 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOM and STOML3 co-localize with the endosomal marker Rab11. Single optical plane confocal micrographs of coronal sections of the OE of WT and Stoml3 KO mice stained with antibodies against STOM (a and d, red) or STOML3 (g and j, red). The same slices were double-stained with anti-Rab11 (b, e, h, and k, green). As described before, STOM and STOML3 mainly localize in the cilia (see insets) and in puncta in the cell body of OSNs. Rab11 is scattered throughout the OE, although it looks particularly enriched apically in the knobs of OSNs (b, e, h, and k) where both STOM (a, d, c and f) and STOML3 (g, j, i and l) localize. Nuclei were stained with DAPI (blue). Insets scale bar 10 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-5-41598_2022_15572_Fig9_HTML.jpg"
} | 009310 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STOML2 is expressed in ensheathing cells but not in olfactory sensory neuron axons. Confocal micrographs of coronal sections of the OB of WT (a–c), Triple KO (g-i), and Stoml3 KO (j-l) mice double-stained with anti-STOML2 (red) and anti-OMP (green) antibodies. In all three mice models, STOML2 has a uniform and strong expression in the external nerve layer of the OB while is weakly present in more internal layers including the glomeruli. (d-f) Higher magnification of OSN axon bundles shows the localization of STOML2 in ensheathing cells. Nuclei were stained with DAPI (blue).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259621-8-41598_2022_15572_Fig7_HTML.jpg"
} | 009311 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "TEM analysis for MgNPs using essential oil of C. flexuosus from different altitudes of (a) MgS1, (b) MgS2, and (c) MgS3.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259627-0-41598_2022_14984_Fig4_HTML.jpg"
} | 009312 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Qualitative analysis of the generalisation capability of CDL vs CIP. (a) On the left, a sample raw image from the dataset of fluorescent microscopy images (microscopy channels one and two are displayed as red and green channels of the RGB image). On the right, the corresponding (weak) mask is produced with the conventional image processing (CIP) pipeline. The different types of errors are shown in the legend. (b) Examples comparing CIP and CNN based segmentation (CDL) on previously unseen data. Top row: part of original HTS image, middle row: CIP Segmentation, bottom row: CDL segmentation. Errors of the segmentation are highlighted by black arrows. Note the improvements the CNN learned over the CIP which was used to generate training data.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259641-2-41598_2022_15623_Fig2_HTML.jpg"
} | 009313 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Localization of β-catenin, active β-catenin and ERK2 expression in hsa-miR-143-3p transfected cells in 3D RAFT. Representative confocal images of transfected primary limbal epithelial cells grown on 3D RAFT TEs immunostained for (a) β-catenin, (b) active- β-catenin and (c) ERK2. The nuclei were stained with DAPI (blue) and protein expression with Alexa Fluor 555 (red). Compared to the control and mimic transfected cells, the expression of β-catenin, active-β-catenin and ERK2 were higher in inhibitor transfected cells along with strong nuclear translocation. The relative protein expression values based on fluorescent intensity are provided in Fig. S5. Scale bar 50 µm. Nuclear localization of active-β-catenin and ERK2 indicates the activation of Wnt-β-catenin and MAPK signaling respectively.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259643-0-41598_2022_15263_Fig6_HTML.jpg"
} | 009314 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Localization of protein expression in hsa-miR-143-3p transfected cells. Representative confocal images of transfected limbal primary culture cells immunostained for DVL3, KRAS, MAPK1, MAPK14, β-catenin, Active β-catenin, AXIN2, ABCG2, p63⍺ and Cx43. Nuclei were stained with DAPI (Blue) and the protein expression with Alexa Fluor 555 (green) except for ABCG2 with Alexa Fluor 488 (red). Scale bar 50 µm. The detailed split channel images along with their relative fluorescent intensity are provided in Fig. S3.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259643-3-41598_2022_15263_Fig3_HTML.jpg"
} | 009315 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Effects of defective regulation of the cellular c-di-AMP level on P. gingivalis cell envelope, the immunoreactivity of LPS, and gingipain activities.A Cells were stained with osmium tetroxide and uranyl acetate and imaged by transmission electron microscopy. Cells of ∆cdaR mutant displayed a significant shape and cell envelope heterogeneity represented by rod- and round-shaped cells with fully or partially intact cell envelopes that are overloaded with OMVs varying in shape and size (1); cells with an intact monolayer of membrane encompassing agglomerated cytoplasmic materials (2) or entirely void round-shaped structures with an intact monolayer of the membrane (3), cells displaying bare peptidoglycan layers (4). B ELISA assays of cell lysates using anti-P. gingivalis LPS monoclonal antibody. The graph represents the mean ± SE of the immunoreactivity of cell lysates (three biological replicates). The standard curve is presented in Supplementary Fig. 10. C Gingipain-dependent proteolytic activities of P. gingivalis strains cells. Graphs represent the mean ± SE (three biological replicates) of the activity of arginine (BAPNA) and lysine (ALPNA) gingipains which were analyzed with a Student’s t test (**P < 0.01; ***P < 0.001; ****P < 0.0001). Scatter plots in Supplementary Fig. 9 display the data distribution. Sup cell-free supernatant, BAPNA N-α-benzoyl-l-arginine-p-nitroanilide, ALPNA N-α-acetyl-l-lysine-p-nitroanilide.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259658-1-41522_2022_316_Fig5_HTML.jpg"
} | 009316 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Bacterial cells morphology observed with scanning electron microscopic evaluation. (A) Control group with normal morphology (round cells with bright surface and without any apparent cell lysis) (10,000×). (B) Biofilm sample treated with 0.075 C, with abnormal morphology (flattened and shrunken cells with rough surface and with some lysed cells marked with white arrows) (8000×). (C) Biofilm sample treated with 0.25 C, with more abnormal bacterial cell morphology (flattened and shrunken cells with rough surface and more lysed cells marked with white arrows) (9500×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259664-5-41598_2022_15666_Fig6_HTML.jpg"
} | 009317 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "p63 silencing in combination with Hand2/Myocardin enhances human cardiac reprogramming. (A) Cardiomyocyte and fibroblast marker gene expression assessed by qRT‐PCR (n = 3, ***p < 0.001, **p < 0.01, *p < 0.05), shNT short hairpin non-targeting. (B) Representative flow cytometry plots for cardiac troponin T positive (cTnT +) human cardiac fibroblasts 2 weeks after their treatment with shp63 with or without Hand2/Myocardin (H/M) versus GMT) with or without shp63. (C) Quantification of the percentage of cTnT+ cells treated as indicated, as assessed by flow cytometry (n = 3; ***p < 0.001). (D,E) Representative immunofluorescence staining for 4ʹ,6‐diamidino‐2‐phenylindole (DAPI) (blue), GFP (green), and (red) cardiomyocyte markers cTnT (D) and α‐actinin (E) after 2 weeks. Scale bar = 100 μm. (F,G) Representative high magnification images of immunofluorescence staining for cTnT (F) and α-actinin (G) after 4 weeks of shp63+ H/M transduction demonstrating sarcomeric structures, most clearly visible in α-actinin labeled cells. Scale bar: 25 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259667-2-41598_2022_15559_Fig2_HTML.jpg"
} | 009318 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Functional efficacy of human cardiac fibroblast reprograming after co-culture with neonatal rat cardiomyocytes. Adult human cardiac fibroblasts were treated with lentivirus expressing GMT (left), shp63 in combination with Hand2/Myocardin (middle) or p63-TID+ Hand2/Myocardin (right). One week after initial transduction, these human cardiac fibroblasts were co-cultured with (untreated) neonatal rat cardiomyocytes (negative for GFP [green fluorescent protein]). (A) Representative immunofluorescence demonstrating (green) GFP expression by human cardiac fibroblasts treated with GMT (left), shp63+ H/M (middle) or p63-TID+ H/M (right) after 4 weeks in co-culture with (non-transduced) neonatal rat cardiomyocytes. Bar = 100 μm. (B) Representative peaks from GFP+ human cardiac fibroblasts treated with GMT, shp63+ H/M and p63-TID+ H/M after 4 weeks of co-culture, reflecting contraction (top row) and Ca2+ transients (bottom row). Contractility parameters were not observed in cells treated with GMT alone. Bar = 1 s.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259667-3-41598_2022_15559_Fig5_HTML.jpg"
} | 009319 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Disordered and plaque-like PAS appear with aging along with conversion to covered or “closed” PAS types in APP/PS1 mice.In old (13 months) mice, pial distribution is irregular at the brain surface and around penetrating arterioles (a), resulting in PAS without any pial coverage, i.e., Type 0 (b), and PAS with thickened, superficial plaque-like coverage, i.e., Type D (c), in addition to usual type PAS (i.e., Type a–c). The anatomy of Type 0 and Type D PAS are depicted in schematics shown in (d) and (e), respectively. PAS types observed in old and APP/PS1 mice are illustrated in (f) and (g). The overall distribution of PAS types at the cerebral cortical brain surface of old mice is summarized in (h). The overall distribution of PAS types at the cerebral cortical brain surface of APP/PS1 mice is summarized in (i). Note diminishment of type 0 and absence of type C PAS in APP/PS1 mice. Old: n = 139 vessels from 3 mice; APP/PS1: n = 141 vessels from 3 mice. Cyan/CY5, MeX04; blue, lectin; green/FITC, ERTR7. Scale bars = a 50 μm; b, c 10 μm; f, g 20 µm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259669-0-41467_2022_31257_Fig7_HTML.jpg"
} | 009320 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "CSF tracer undergoes differential macrophagic processing within distinct PAS types.At sites of arteriolar penetration (a), the intimal pia and epipia merge and distinct patterns of tracer deposition are observed around ensheathed vessels (i.e., Type A-D PAS), with free tracer passage, stagnation of the tracer bolus (open arrow) and/or cellular sequestration of tracer (solid arrows) noted. Cross and oblique PAS sections (b, lower panel) depict tracer-positive cells studding the ERTR7-positive PAS cell network. As demonstrated in the oblique section and lower panel representing an enlargement of the boxed area, the TxRd tracer positive cells represent ED1-positive macrophages. ED1-positive cells are shown within Type B PAS of young, old, and APP/PS1 mice (c) and the distribution of tracer among ED1-positive macrophages in type A–D PAS of young mice is shown in (d). The number of ED1-expressing cells is variable among PAS types, being prominent in type D PAS (e) and correlating strongly with ERTR7 density (f); n = 107 vessels. Two-way ANOVA with Tukey’s multiple comparisons test in D. Simple linear regression with 95% CI in E, F; P values in legend refer to testing between slopes. Moreover, the depths of ED1-positive macrophages in PAS correlate strongly with pial (i.e., ERTR7) depth (g). The distribution of tracer among ED1-positive macrophages in type A–D PAS is quantified in (h). Two-way ANOVA with Tukey’s multiple comparisons test in (h). a–g Red/Texas Red, TxRd; green/FITC, ERTR7; white/CY5, ED1; blue, DAPI; Scale bars = (a, upper panel) 30 μm; (a, lower panels, b upper panel, c, g) 10 μm; (b, lower panel) 5 µm. Young: n = 87 vessels from 3 mice; Old: n = 71 vessels from 3 mice; APP/PS1: n = 66 vessels from 3 mice. Data are presented as mean ± SEM. Source data are provided as a Source Data file.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259669-3-41467_2022_31257_Fig9_HTML.jpg"
} | 009321 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The pia is not a barrier to CSF tracer transport (size 66 kDa), irrespective of periarteriolar space (PAS) type.a A CSF tracer (bovine serum albumin conjugated to Texas Red, TxRd-BSA; 66 kDa) was injected into the cisterna magna of live ketamine–xylazine anesthetized mice. After dura had been removed, the pial surface and CSF tracer movement patterns were imaged through a cranial window using two-photon (2P) laser scanning microscopy. b Second harmonic generation (SHG) was used to visualize the collagen fibers in the inner arachnoid and pia. c SHG imaging of an arteriole in the subarachnoid space (SAS), with an orthogonal reconstruction in the XZ plane (top panel), showing the inner arachnoid overlying the vessel surrounded by epipia coursing within the SAS on top the intimal pial layer. d SHG imaging of a penetrating arteriole (PA) showing how the epipia coalesces with the intimal pia as it dives down into cerebral cortex. Bottom right: YZ orthogonal view of the PA entering cortex. e Representative images of each PAS type surrounding penetrating arterioles at −20, −30, −40 µm below the cortical surface: Type A (top panel), Type B (middle panel), Type C (bottom panel). f CSF tracer in the surface perivascular spaces (PVS) is surrounded by the inner arachnoid superiorly, the intimal pia inferiorly, the fusion of the inner arachnoid/intimal pia laterally, and the epipia of the accompanying artery medially. This space coincides with the SAS of the surrounding leptomeningeal arterioles. g CSF tracer enters penetrating PAS and traverses across the merged epipial and intimal pial membranes. h Distribution of PAS by type (n = 42 PVS from 8 mice). i Area (µm2) of tracer coverage in the PVS as a function of depth from the brain surface. One-way ANOVA with Tukey’s post hoc for multiple comparisons, P = 0.4257, ns: not significant. j Probability of observing CSF tracer influx at varying depths of PAS type at 60 min after injection. Log-rank (Mantel–Cox) test, P = 0.7952, ns. k Time to tracer influx after the start of the intracisternal tracer injection in minutes (min). One-way ANOVA, P = 0.6399, ns. Scale bars = b–d, f, g 20 µm. Data are presented as mean ± SEM. Source data are provided as a Source Data file.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259669-5-41467_2022_31257_Fig5_HTML.jpg"
} | 009322 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The epipia attenuates and loosens around small-to-medium leptomeningeal arteries, forming the epipial space.Schematic (a) and routine sections (b–d) demonstrate the relationships of pial cells on leptomeningeal, i.e., subarachnoid space (SAS) arteries and penetrating arterioles. Medium-sized SAS arteries at the brain surface demonstrate attenuation and loosening of the epipia layer, creating an epipial space (e), whereas smaller SAS arteries and penetrating arterioles demonstrate further thinning and coalescence of pial layers with the vessel walls, with occasional envelopment of the arteriolar smooth muscle cell layer (f, g). Analysis of epipial sheath thickness, expressed as a percentage (%) of vessel area, is shown according to vessel size (h) and brain region (i); Pearson correlation coefficient; n = 86 vessels. Likewise, analysis of epipial fenestration, expressed as a percentage (%) of total vessels, is shown according to brain region (j) and vessel size (k); one-way ANOVA with Tukey’s multiple comparisons test; n = 122 vessels. A medium-sized artery in ventral mouse brain (l, the same vessel shown in e), is depicted at higher magnification and demonstrates the loosened epipial sleeve composed of interlinking pial cells that partially enclose the epipial space (asterisks). Features of the epipial space are highlighted by immunohistochemistry (l, right-hand side), and are shown to advantage in ultrastructural images (m). Enlargements of boxed micrograph areas demonstrate the intra-adventitial space, in which scattered collagen fibrils are appreciated (arrows). Analysis of epipial space areas are shown relative to vessel size (n); Pearson correlation coefficient; n = 115 vessels from 6 mice. Analysis of epipial space areas are shown relative to brain region (o); one-way ANOVA with Tukey’s multiple comparisons test; n = 115 vessels from 6 mice. (b–d, L left) H&E; (e–g, L right) red/CY3, SMA; green/FITC, ERTR7; blue, DAPI; m transmission electron micrographs, with scale bars as indicated (asterisks represent the epipial space); scale bars = (b) 100 μm; c–e 20 μm; f, g 10 μm. Source data are provided as a Source Data file. TEM data are representative of 50 vessels from 3 mice.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259669-6-41467_2022_31257_Fig2_HTML.jpg"
} | 009323 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Influx of CSF tracer is delayed, but not restricted across “covered” Type A and Type B PAS.Distribution of an immunofluorescent tracer (Texas Red conjugated to bovine serum albumin, TxRd; mw 66 kDa) was evaluated in mice sacrificed at 15 versus 30 min following slow intracisternal infusion (a), and revealed heterogeneous spatiotemporal deposition patterns as shown in right-hand images that represent the boxed areas. Enlargement of the small box at lower right panel in a illustrates tracer passage into a Type B PAS (b). Enlarged inset depicts pooling of tracer in PAS, creating a scalloped appearance around smooth muscle cells (b, inset). Cross-sectional images from axial sections (labeled 1–3) of another Type B PAS is shown in the middle panel and the anatomic relationships are summarized in axial schematics on right-hand side. Triple labeling of a Type B penetrating arteriole (shown in longitudinal section) depicts TxRd tracer signal around the ERTR7-labeled pial cell elements (c). Volumetric lightsheet image of a tissue-cleared (CLARITY) specimen further demonstrates variable penetration of the tracer (d). Examples of tracer-positive PAS are shown (e) and distributions are quantified in different brain regions at 15 min (f, h) and 30 min (g, i) post-infusion; n = 57 vessels from 6 mice. j At 30 min post-infusion, tracer was mostly found around large diameter arteries; n = 141 vessels from 6 mice. Red/Texas Red, TxRd; green/FITC, ERTR7; white/CY5, SMA; blue, DAPI or lectin; scale bars = a 500 μm; b–e 10 μm. Source data are provided as a Source Data file.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259669-7-41467_2022_31257_Fig4_HTML.jpg"
} | 009324 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "RNAscope in situ hybridization indicates that most of the endopiriform nucleus (EPN) cells are VGLUT1 (Slc17a7) positive and ~ 60% of these cells co-express Oxtr, with a small population of GABAergic Oxtr+ cells. Some neurons that express Oxtr mRNA (red) co-express mRNA for the GABAergic markers (black arrows), Gad1 (A, blue) or Gad2 (B, blue). However, most Oxtr expressing cells were negative for these markers (white arrows). Most of the Oxtr expressing neurons in EPN co-express the markers for VGLUT1 (Slc17a7) (C, E, blue, black arrows) with only a few that expressed only Oxtr (C, F, white arrows). Expression of the marker for VGLUT2 (Slc17a6) (D, blue) was low in EPN but some co-expression with Oxtr was detected (black arrows). The percentage of Oxtr expressing EPN neurons that co-express one of the other markers studied here is shown in E, while the percent of EPN neurons that express one of the other markers that co-express Oxtr is shown in F.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259672-2-41598_2022_15390_Fig2_HTML.jpg"
} | 009325 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "OXTR-EGFP expressing neurons in the endopiriform nucleus (EPN). During initial electrophysiological recordings, biocytin was added to the intracellular solution and injected into the recorded cell. Post-labelling of these cells (A) revealed anatomical location of neurons recorded from during electrophysiological experiments. Endogenous expression in the OXTR-EGFP mouse tissue slice (300 µm) shows dense OXTR-EGFP expression in the EPN (B). The combined image (C) shows that the location of the cell recorded from was the OXTR-EGFP rich EPN.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259672-4-41598_2022_15390_Fig3_HTML.jpg"
} | 009326 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Space correction technique with kinesio taping.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259681-0-41598_2022_14154_Fig2_HTML.jpg"
} | 009327 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Paravertebral inhibition technique with kinesio taping.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259681-2-41598_2022_14154_Fig1_HTML.jpg"
} | 009328 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Artifacts are heterogeneous, and range in shapes and sizes. A UMAP projection of all artifacts from the seven cell lines dataset. The inputs to the UMAP are the pixels of each patch that contains an artifact and the outputs are the first two features in the UMAP embeddings of each patch. We then used these two features respectively as ‘x’ and ‘y’ values to plot the corresponding input patch in 2D space.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259686-0-41598_2022_14703_Fig2_HTML.jpg"
} | 009329 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Visual impact of artifacts on nuclei segmentation. Two pairs of brightfield images with corresponding nuclei segmentation (in dark red) overlaid. Zoomed-in purple circles represent examples of artifact-free areas and artifactual areas (light red). White contours: artifact borders; yellow-ish white contours: nucleus ground truth borders; arrows and text: guides to corresponding regions and elements.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259686-4-41598_2022_14703_Fig4_HTML.jpg"
} | 009330 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Mitochondrial network analysis.A Representative images maximal z-stack projections of mitochondrial networks stained with MitoTracker CMXRos. B Mitochondiral networks assessed after thresholding using the particle analysis tool. C Mitochondrial network analysis of skeletonised images using the MiNA plugin. *p < 0.05, **P < 0.01, ***p < 0.005. N = 20. Scale bar 25 µm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259687-3-41431_2022_1102_Fig4_HTML.jpg"
} | 009331 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "TEM cross-section image of VO2 thin films deposited onto silica substrates at temperatures of (a) 400 °C (VT400) and (b) 700 °C (VT700); (b,e) corresponding HRTEM and SAED patterns; (c,f) EDS chemical mapping obtained during cross-sectional HAADF-STEM analysis of different types of atoms(V, O, and Si).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259692-0-41598_2022_15439_Fig2_HTML.jpg"
} | 009332 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Top-view SEM images of the VO2 thin film deposited: VT400 [(a)], and VT700 [(b)].",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259692-6-41598_2022_15439_Fig1_HTML.jpg"
} | 009333 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Detection of H2S-releasing enzymes in mouse testis: (a) immunofluorescence of testis sections. Acrosomal development stages of spermatids were recognized using PNA (200×). Individual stages of acrosomal biogenesis, representing the Golgi, cap, and acrosomal (Acr) stages, are emphasized (1000×). Scale bar 100 µm. (b) Cystathionine β-synthase (CBS), cystathionine γ-lyase (CTH) and 3-mercaptopyruvate sulfurtransferase (MPST) were detected by Western blot. (c) The comparison of prepubertal (young) and adult males was performed. (d) Colorimetric detection of H2S production in testes, which increased after the addition of pyridoxal-5′-phosphate (PxP) and l-cysteine.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259693-4-41598_2022_15360_Fig3_HTML.jpg"
} | 009334 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Production of H2S, its enzymes and persulfidation (–(S)nH) in mouse spermatozoa. (a) Western blot detection of cystathionine β-synthase (CBS), cystathionine γ-lyase (CTH) and 3-mercaptopyruvate sulfurtransferase (MPST) in mouse spermatozoa during their maturation in the epididymis. (b–d) Immunocytochemistry of CBS, CTH and MPST. (e) Localization of H2S production by Sulfane Sulfur Probe 4 (SSP4) and (f) –(S)nH. Spermatozoa were magnified (1000×).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259693-5-41598_2022_15360_Fig4_HTML.jpg"
} | 009335 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "PET/CT performed for staging of alveolar echinococcosis in a 55-year old man (patient 02 in Table 3) showed mild metabolic activity [in maximum intensity reconstructions of PET (A) and fused PET/CT images (B)] at the margins of a round and hypodense lesions in the right liver lobe [as shown on axial contrast-enhanced CT images in (C)]. SUVmax was 4.7 in the echinococcosis manifestations, and 3.2 in non-infected liver tissue; SUVratio was 1.5. After 1000 days of benzimidazole therapy, levels of Em-18 antibodies became undetectable, but therapy was not yet stopped at the end of the present study period (in total after 1131 days of therapy).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259695-2-41598_2022_15641_Fig2_HTML.jpg"
} | 009336 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "PET/CT performed for staging of alveolar echinococcosis in a 37-year old woman (patient 23 in Table 3) showed intense metabolic activity [in maximum intensity reconstructions of PET (A) and fused PET/CT images (B)] in a hilar lesion infiltrating the pancreas (dilated pancreatic duct on axial contrast-enhanced CT images in (C). SUVmax was 11.1 in the echinococcosis manifestation, and 3.1 in non-infected liver tissue; SUVratio was 3.6. After 1458 days of benzimidazole therapy, levels of Em-18 antibodies became undetectable, but therapy was not yet stopped at the end of the present study period (in total after 1633 days of therapy).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259695-3-41598_2022_15641_Fig1_HTML.jpg"
} | 009337 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Clinical ascertainment and genetic analysis.A Pedigree of the family under study, summarising four generations and the consanguineous union of the parents of the two affected individuals (IV3 and IV5). Individuals recruited to the study are indicated by Roman numerals, and individuals whose DNA samples have been used for WES are marked with a star (*). B–G MR images of individual IV3 (B–D) aged 14 years, and his brother IV5 (E–G) aged 6 years. T2 axial images (B, C & E, F) demonstrating lack of hemispheric myelin visible through T2 hyperintensity (brightness indicated by white arrows). Prominence of cerebellar folia and vermian hypoplasia (C & F) indicates cerebellar volume loss. T1 sagittal images (D & G) demonstrate a thin corpus callosum (D, indicated by white arrowhead) and mild upper vermian volume loss. H Ideogram illustrating the shared homozygous regions of the two affected individuals in red, and a table summarising the significant homozygous regions in chromosome order. The largest homozygous region on chromosome 2 that contains MAL is marked by the red asterisk (*). I Segregation analysis of the MAL c.326 C > A p.(Ala109Asp) variant (indicated by red asterisk, *) within the family confirmed by Sanger sequencing. het heterozygous, ho homozygous.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259702-2-41431_2022_1050_Fig1_HTML.jpg"
} | 009338 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "STM height images of the macrocycles adsorbed on HOPG. a) Z,Z‐8T6A. b) E,E‐8T6A. c) 8T8A. d) E‐8T7A. Tunneling parameters: average tunneling current = 90–100 pA, bias voltage = 800–1100 mV (see Table S1 of the Supporting Information for details on the unit cell parameters).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259718-0-ADVS-9-2200557-g001.jpg"
} | 009339 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Layer morphology characterization using AFM and STM. a) AFM image of the functionalized SLG/SiO2 using the grafting ink (80 × 10−3 m NBD in DMSO) for 10 min. b) Amplified AFM image with a scratched area and line profile for layer height determination. c) STM image of the functionalized SLG/SiO2 using the grafting ink (80 × 10−3 m NBD) for 10 min. d) STM image of the functionalized SLG/Cu using the grafting ink (80 × 10−3 m NBD) for 10 min.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259721-0-ADVS-9-2105017-g002.jpg"
} | 009340 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "a) SEM images of 1,2,4‐HPB‐COF synthesized from different alcohols with different magnification. b,c) TEM images of 1,2,4‐HPB‐COF at different scale bars. d,e) TEM images of 1,3,5‐HPB‐COF at different scale bars.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259724-4-ADVS-9-2105517-g003.jpg"
} | 009341 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Structural and electronic characterization of P2 on Au(111). a) Chemical scheme illustrating the on‐surface synthesis of P2. b) Overview STM image of the deposition of a submonolayer coverage of 4Br4AzaPn precursor on Au(111) after annealing at 100 °C. V\nb = 1 V, I\nt = 25 pA, scale bar = 3 nm. c) HR‐STM image of P2. V\nb = 20 mV, I\nt = 5 pA, scale bar = 2 nm. d) nc‐AFM image of P2 showing the non‐planar twisted geometry. e) Laplace filtered nc‐AFM image confirming the formation of the pyrrolopyrrole bridge. f) Superposition of chemical scheme on (e). d–f) V\nb = 5 mV, scale bar = 5 Å. g) Scanning tunneling spectra acquired on the position depicted in (c) and on Au(111).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259725-4-ADVS-9-2200407-g004.jpg"
} | 009342 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "a) Detonation NDs produced by detonation of carbon‐containing explosives; diamond‐containing soot is collected from the bottom and the walls of the chamber. Left: Reproduced with permission.[\n\n62\n\n] Copyright 2012, Nature Publishing Group. Right: Reproduced with permission.[\n\n63\n\n] Copyright 2007, Wiley‐VCH. b) High‐resolution TEM image of pristine detonation NDs. Reproduced with permission.[\n\n63\n\n] Copyright 2007, Wiley‐VCH. c) NDs produced by the HPHT methods. Reproduced with permission.[\n\n55\n\n] Copyright 2015, American Vacuum Society. d) TEM image of HPHT NDs. Reproduced with permission.[\n\n64\n\n] Copyright 2014, Elsevier. e) Illustration of the GeI4‐mediated synthesis of nanodiamonds under mild HPHT conditions. Reproduced with permission.[\n\n40\n\n] Copyright 2020, Elsevier.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259730-9-ADVS-9-2200059-g003.jpg"
} | 009343 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Morphological changes of crab uropods during molting stages under a light microscope (A,B are shown at ×50 magnification; C–F at ×400 magnification). The observed physical characteristics of each stage are as follows: Pre-molt stage (A): a noticeably wider clear zone between the setal cones and the epidermis, and new setae are fully generated; post-molt stage (B): soft and delicate setae and dense connective tissue; Intermolt stage (C): setae harden and the absence of setal cones; (D) fully-spread epidermis; (E) a clear margin of epidermal tissue at the base of the setal cones; (F) a narrow zone between the setal cones and the epidermis; setal cones arise.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259733-6-41598_2022_14783_Fig1_HTML.jpg"
} | 009344 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Low pSer616 DRP-1 correlates with high MHC-I and indicates a better prognosis in cancer patients.A Representative immunofluorescence images for MHC-I and pSer616 DRP-1 of HNSCC, NSCLC, and melanoma patients with different postoperative survival time (MHC-I: green, pSer616 DRP-1: red). DAPI, nuclear staining. Scale bars, 10 μm. B, C Representative immunochemistry images and scores for MHC-I and pSer616 DRP-1 of HNSCC patients with different postoperative survival time. Magnification, ×200 and ×400 (mean ± s.e.m; p < 0.0001 for MHC-I and p = 0.0173 for pSer616 DRP-1; **p < 0.001 by two-tailed t-test). D Spearman order correlation analysis of MHC-I and pSer616 DRP-1 association in HNSCC, NSCLC, and melanoma based on IHC score (p < 0.0001 for HNSCC, NSCLC and Melanoma) E Kaplan–Meier survival curves for HNSCC, NSCLC, and melanoma patients are plotted for pSer616 DRP-1 and MHC-I expression. Survival differences were analyzed using log-rank test (p < 0.0001 for HNSCC, p = 0.0392, p = 0.0021 for NSCLC and p = 0.0076, p = 0.0138 for Melanoma).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259736-1-41467_2022_31417_Fig1_HTML.jpg"
} | 009345 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Cell density profiles and two-dimensional distribution of neurons. Top (colored) line: two-dimensional averaged histograms of NeuN immunostained sections from regions of interest in control and probe disrupted cortical areas. Vertical plots show mean cell density as a function of cortical depth, while horizontal traces show mean cell density as function of electrode distance (or in control sections the edge of region of interest). Bottom (grayscale) line: Characteristic examples of NeuN sections for each experimental group.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259743-1-41598_2022_15367_Fig4_HTML.jpg"
} | 009346 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "SEM images of nano-sized Fe3O4 (a), biosilica (b), biosilica/Fe3O4 (c) and MBA nano-hybrid (d).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_5-PMC9259746-6-41598_2022_15844_Fig1_HTML.jpg"
} | 009347 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Subsequent chest X-ray after thoracostomy revealed a decreased left-sided pleural effusion, a decreased tracheal deviation, and an increased right lung field.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272902-0-cureus-0014-00000025853-i02.jpg"
} | 009348 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Initial chest X-ray revealed a large left-sided pleural effusion with significant rightward tracheal deviation and a diminished right lung field.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272902-1-cureus-0014-00000025853-i01.jpg"
} | 009349 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "X-ray chest in a single viewThe central line of the right internal jugular vein (IJV) as highlighted by an arrow is visible, with the tip protruding into the predicted location of the mid- superior vena cava (SVC). There is no evidence of pleural effusion or pneumothorax. Bilaterally, ill-defined patchy mild interstitial alveolar opacities are visible as highlighted by arrows.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272903-1-cureus-0014-00000025787-i02.jpg"
} | 009350 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Hair follicles are regenerated with icariin+PEG hydrogel treatment. (A) Masson staining of different groups on day 14. Red arrows indicate new hair follicles. Scale bar: 200 μm. (B) Representative immunofluorescence images of K17 expression on day 14 at the injured sites. Scale bar: 100 μm.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272914-0-fbioe-10-902894-g005.jpg"
} | 009351 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Icariin+PEG hydrogel promoted macrophage M2 polarization and reduced inflammation in the early stage of wound healing in vivo. (A) Representative immunofluorescence pictures of ARG1 expression on day 7 at the injured sites. Scale bar: 100 μm. (B) Quantification of ARG1-positive cells in different groups. (C,D) Protein expression level of CD206 and ARG1 as detected by western blotting on day 7 at injured sites. Quantification of the western blotting bands compared to that of the control group. (E) Expression levels of M2-related genes ARG1 and IL-10 of the three groups by RT-PCR. (F) Protein expression level of TNF-α as detected by western blotting on day 7 at the injured sites. Quantification of the western blotting bands compared to that of the control group. (G) Expression level of inflammation-related genes IL-6, IL-8, and TNF-α in different groups by RT-PCR. (H) Representative immunofluorescence pictures of iNOS expression on day 7 at injured sites. Scale bar: 100 μm. Quantification of iNOS-positive cells in different groups.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272914-3-fbioe-10-902894-g004.jpg"
} | 009352 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Icariin+PEG hydrogel promoted M2 polarization of macrophages and enhanced anti-inflammatory effects in vitro. (A) Morphological changes of THP-1 macrophages after icariin treatment for 48 h were observed under an optical microscope. Red arrows indicate elongated macrophages. (B) Representative pictures of THP-1 immunofluorescence staining with CD206 antibody after being co-cultured with the hydrogel for 48 h. Scale bar: 100 μm; scale bar of magnified pictures: 25 μm. (C) Western blot analysis of the CD206 protein expression level in macrophages treated with different dressings for 48 h. Quantification of the western blotting bands compared to that of the control group. (D) RT-PCR analysis of M2-related gene (ARG1, CD206, and IL-10) expression in macrophages. (E) RT-PCR analysis of M1-related gene (IL-6, IL-8, and TNF-α) expression in macrophages.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272914-8-fbioe-10-902894-g006.jpg"
} | 009353 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Effect of compound 12a on cells migration and healingefficacy of Caco-2 cells.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272924-14-IENZ_A_2085693_F0003_C.jpg"
} | 009354 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The expression level of TLR3, TLR4, TLR7, and TLR8 in the proteomics level.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272932-2-IANN_A_2095664_F0006_C.jpg"
} | 009355 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Intraoperative photograph demonstrating the defect and the infraclavicular incision, made 6–10 cm lateral to the sternoclavicular joint.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272936-0-ICRP_A_2094270_F0002_C.jpg"
} | 009356 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Intraoperative photograph demonstrating the pedicle, identified below the retracted clavicular and sternal heads of pectoralis major.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272936-1-ICRP_A_2094270_F0003_C.jpg"
} | 009357 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "(a) MDA-MB-231 cells were treated with 7Cc, sterile pipette tips were used to scratch evenly, the incubation was continued, and representative images were captured. (b) MDA-MB-231 cells were seeded onto chambers and incubated with 7Cc, stained with crystal violet, and representative images were photographed. (c) MDA-MB-231 cells were incubated with 7Cc, then fixed, washed and photographed with a fluorescence microscope. All data are represented as the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 vs the control group. Statistical analyses were carried out on GraphPad.Prism software under ordinary one-way ANOVA method and compared with a control group.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272937-4-IENZ_A_2096020_F0006_C.jpg"
} | 009358 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "MDA-MB-231 cells were incubated with 7Cc. Comet assay was used to evaluate DNA damage and photomicrographs were provided. Data are represented as mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 vs control group. Statistical analyses were carried out on GraphPad.Prism software under ordinary one-way ANOVA method and compared with a control group.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272937-5-IENZ_A_2096020_F0007_C.jpg"
} | 009359 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Light photomicrographs showing histopathological sections of (a) control untreated rat lung and (b) rat lung received an intratracheal suspension of TBN-NVS formulation (200X H & E).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272939-1-IDRD_A_2092236_F0007_C.jpg"
} | 009360 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Transmission electron micrograph of the optimized TBN-NVS formulation.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272939-2-IDRD_A_2092236_F0005_B.jpg"
} | 009361 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "TEM micrograph of PEI/PTA(5/5) (a), PEI/PTA(5/5)/BS 100(0.2 mM) (b), and PEI/PTA(5/5)/BS 100(1.0 mM) (c) suspension (Arrows in (c) indicates tiny particles.) (A). TEM micrograph of PEI/PTA(5/5) (a), PEI/PTA(5/5)/CPC(0.2 mM) (b), and PEI/PTA(5/5)/CPC(1.0 mM) (c) suspension (B). TEM micrograph of PEI/PTA(5/5) (a), PEI/PTA(5/5)/SLS(0.2 mM) (b), and PEI/PTA(5/5)/SLS(1.0 mM) (c) suspension (C).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272940-3-IDRD_A_2027571_F0003_B.jpg"
} | 009362 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "SNR efficiency in vivo. The values were obtained from simulations as well as estimated from experimental data, for different aspect factors. In central white matter and the corpus callosum, trends up to α = 5 are similar to simulations with T1 = 0.8 s, mimicking white matter. The SNR efficiency in brainstem and cerebellum is more similar to simulations with T1 = 1.6 s, mimicking gray matter. Generally, the SNR efficiency in white matter is overestimated by the simulations (black circles) compared with measurements (triangles). Note that SNR efficiency is above unity in all cases.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272945-1-nihms-1815196-f0006.jpg"
} | 009363 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Direct sampling and super-resolution reconstruction (SRR) for various aspect factors (α). Image were obtained in a healthy brain in vivo at b = 0 ms/μm2 and reconstructed at a resolution of 1.6 × 1.6 × 1.6 mm3. All images were reconstructed with moderate regularization and are thus matched in terms of effective resolution (σ = 0.47 voxels), meaning Gaussian smoothing was applied to the direct case. Due to different signal intervals, the maximum of the colormap is scaled separately for each image. Note that the overall image contrast changes with aspect factor due to T1 effects because a higher aspect factor allows a shorter TR. This results in a smaller signal difference between the white matter (T1 = 0.8 s) and the cerebrospinal fluid (T1 = 4.3 s).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272945-10-nihms-1815196-f0005.jpg"
} | 009364 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "In vivo illustration of the accuracy-related benefit of super-resolution reconstruction (SRR). The figure shows diffusion-weighted images from a SRR protocol (left) and direct acquisition (middle) with spherical encoding at b = 4 ms/μm2 in coronal and sagittal view at 1.6 × 1.6 × 1.6 mm3. As regularization in SRR slightly decreases spatial resolution, we also compare to a direct acquisition at 1.8 × 1.8 × 1.8 mm3 (right). A vastly higher contrast is observed with SRR compared with direct sampling at both the target resolution and the slightly reduced resolution. Quantitatively, this corresponds to an increase in the contrast ratio between the cerebellar cortex and white matter to 1.86 from 1.06 (middle) or 1.31 (right). Acquisition times are similar.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272945-6-nihms-1815196-f0007.jpg"
} | 009365 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Overview of acquired images. The left image shows a T2-weighted transversal slice across the pelvis from the turbo-spin–echo sequence. The right image shows cropped versions of the diffusion-weighted images, where the columns show different b-values and the rows different shapes of the b-tensor. The contrast obtained with linear tensor encoding (top row) and spherical tensor encoding (bottom row) is similar at low b-values, but starts to deviate at higher b-values. The b-values are reported in units of ms/μm2. LTE, linear tensor encoding; STE, spherical tensor encoding; T2w, T2-weighted",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272946-2-nihms-1815206-f0002.jpg"
} | 009366 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Examples of histology slices. The slices were obtained from selected cases with lowest and highest values of isotropic kurtosis (MKI) and anisotropic kurtosis (MKA). Top row shows examples of cancers having low MKI to the left (Gleason score = 4 + 4, peripheral zone [PZ]) and high MKI (Gleason score = 3 + 4, transitional zone [TZ]) to the right. The higher MKI seems to be related to a higher amount of stroma surrounding the ducts, which appears to add to the heterogeneity in diffusion coefficients. Bottom row shows examples of cancers having low MKA to the left (Gleason score = 4 + 4, TZ) and high MKA to the right (Gleason score = 3 + 4, TZ). High MKA appears to have a higher prevalence of elongated cellular structures. Scale bars = 100 μm",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272946-3-nihms-1815206-f0005.jpg"
} | 009367 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Sections reveal dilated lung alveolae, type II pneumocytes hyperplasia. intraalveolar hemorrahge, foamy macrophages, cellular or proteinaceous exudate accompanied by interstitial fibroblastic proliferation and fibrin deposition",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272948-0-cjim-13-303-g002.jpg"
} | 009368 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "CT scan showing bilateral ground glass opacity and bronchiectasis",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272948-1-cjim-13-303-g001.jpg"
} | 009369 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Serial imaging of case 1. The initial CT scan was normal (A). The on-admission CT scan taken after 8 days showed bilateral GGO with consolidative changes within (B). Ten days later, opacities increased in extension and density, with parenchymal band formation and several foci of target appearance (arrows) (C-D).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-0-cjim-13-270-g001.jpg"
} | 009370 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Chest CT scans of cases 8-10. (A) Case 8. CT scan shows a faint small center of denser opacity surrounded with a small area of GGO, which in turn is enclosed with a rim of consolidative opacity (arrowheads). (B) Case 9. Foci of target lesions indicated in both lungs are seen (arrowheads). (C, D) Case 10. Basal mixed density opacities with consolidation predominance containing air bronchogram are demonstrated. Multiple targetoid lesions are noted in both lungs (arrowheads). Arrow indicates two smaller target shaped lesions with some degrees of confluency",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-1-cjim-13-270-g006.jpg"
} | 009371 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Chest CT scans of cases 3-4. (A, B) case 3. CT scan shows several foci of target shaped lesions (arrows). Arrowhead shows parenchymal band indicating the later phases of COVID-19 induced pneumonia. (C, D)\ncase 4. On-admission Chest CT scan shows several foci of target appearance (arrows).",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-2-cjim-13-270-g003.jpg"
} | 009372 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Chest CT scans of cases 5-6.\n(A, B) case 5. A few foci of target appearance were visible in the right lower and right upper lobes (arrows). Several foci of vacuolar sign imply the later phases of COVID-19 pneumonia (arrowhead). (C, D) case 6. Initial chest CT scan depicts several foci of target appearance in both upper and lower lobes bilaterally and in lingula (arrows). Few parenchymal bands are visible in favor of later phases COVID-19 pneumonia",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-3-cjim-13-270-g004.jpg"
} | 009373 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Serial imaging of case 7. Initial CT scan (A, B) depicts rounded consolidative opacities (arrowheads). One week later, two foci of target appearance developed in the right upper lobe and superior segment of right lower lobe (arrows). Mild cardiomegaly and bilateral pleural effusion are also present",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-4-cjim-13-270-g005.jpg"
} | 009374 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Serial imaging of case 2. The on-admission chest CT scan (A-B) depicts diffuse GGO and small foci of poorly developed target appearances (arrows). The second CT scan five days later shows diffuse residual faint GGO (thick arrow), parenchymal subpleural bands (curved arrow), and consolidating changes in both lower lobes. A few bullae (arrowhead) are also developed in the periphery of almost all pulmonary lobes. A small focus of target appearance is also present (arrow)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272949-5-cjim-13-270-g002.jpg"
} | 009375 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "(A): Spiral chest CT scan, (B); Paranasal and periorbital sinus",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272951-0-cjim-13-277-g002.jpg"
} | 009376 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Magnetic resonance imaging findings after the intervention",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272951-1-cjim-13-277-g003.jpg"
} | 009377 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Cervical carotid angiography: (A) Left carotid angiography (lateral view) reveals the dissected part of proximal ICA. (B) Left-side post-stenting angiography (Lateral view). (C) Right carotid angiography (oblique view) shows the pseudo-aneurysm in cervical portion. (D) Right-side post-intervention angiography (lateral view)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272953-0-cjim-13-281-g001.jpg"
} | 009378 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Imaging findings illuminated, ground-glass opacities in lung (each picture are numbered as the cases, respectively)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272959-0-cjim-13-284-g001.jpg"
} | 009379 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Kidney needle biopsy, (A) Hematoxylin and Eosin stain, (B) Masson's trichrome stain; MPGN like glomerular changes with obliterated small arteries consistent with thrombotic microangiopathy",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272963-0-cjim-13-299-g002.jpg"
} | 009380 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Brain MRI without gadolinium; Multiple acute infarction areas in left temporoparietal, right temporofrontal and right parietal cortex are seen",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272963-1-cjim-13-299-g001.jpg"
} | 009381 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Chest X-ray on Admission",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272965-0-cjim-13-289-g001.jpg"
} | 009382 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The pathology of the placenta that indicates vascular thrombosis",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272966-0-cjim-13-295-g002.jpg"
} | 009383 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The image of the placenta has been extracted",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272966-1-cjim-13-295-g003.jpg"
} | 009384 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Ultrasound images of the placenta showing damage and fragmentation",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272966-2-cjim-13-295-g001.jpg"
} | 009385 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Chest x-ray of the patient with COVID-19 infection",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272967-1-cjim-13-161-g002.jpg"
} | 009386 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Photograph of right posterior maxillary showing normal palatal bone tissue and alveolar ridge",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272968-0-cjim-13-307-g001.jpg"
} | 009387 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Cropped panoramic of the right maxillary sinus showing: the normal sinus without opacification",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272968-1-cjim-13-307-g006.jpg"
} | 009388 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Coronal view of CBCT showing complete opacification of right maxillary sinus with calcified particles (red arrows). Notice Invasion to lateral wall of middle turbinate and the right OMC was blocked. Also, there was noticeable of palatal bone erosion (blue arrow)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272968-2-cjim-13-307-g003.jpg"
} | 009389 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Axial view showing erosion of medial and posterolateral and anterior wall of right maxillary sinus in compared to intact and corticated left maxillary sinus walls (blue arrows)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272968-3-cjim-13-307-g004.jpg"
} | 009390 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Sagittal view showing erosion of inferior border of right orbit. Also notice to calcified particle. (Green arrows)",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272968-4-cjim-13-307-g005.jpg"
} | 009391 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "A, B: normal CXR and lung CT",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272969-0-cjim-13-254-g001.jpg"
} | 009392 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "A, B CXR and lung CT findings: ground-glass opacity in both lungs",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272969-1-cjim-13-254-g005.jpg"
} | 009393 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "CXR (A) and lung CT (B) showed bilateral airspace consolidation and ground-glass opacity",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272969-2-cjim-13-254-g002.jpg"
} | 009394 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "A, B CXR and lung CT findings: ground-glass opacity and consolidation in upper and lower lobes of left lung and right lower lobe",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272969-3-cjim-13-254-g003.jpg"
} | 009395 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "A, B CXR and lung CT findings: Multilober GGO and consolidation",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272969-4-cjim-13-254-g004.jpg"
} | 009396 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The region-dependency of CVR and impact of fluctuations in cardiorespiratory activity on brain hemodynamics. (a) CVR maps of two healthy subjects.46 Note the differences of the maps for the two subject, highlighting the significance of inter-subject variability of CVR. In both cases, the CVR is higher in cortical regions compared to interior parts of the brain. Subject 2 has a more pronounced CVR in the frontal and occipital lobes compared to the temporal regions. (b) Spatial heterogeneity of CVR and the influence of age.47 According to this study, the parietal lobe shows the strongest CVR, followed by the temporal, frontal and occipital lobes. Aging was shown to decrease the CVR in the temporal lobe in particular. (c) Age-related decline in CVR.48 Shown is the drop in CVR caused by aging (CVR averaged over the whole brain; 25±3 years versus 61±5 years). (d) The CVR and task-evoke hemodynamic changes depend on the individual resting PETCO2 level.49 Examples from two subjects. fMRI scanning was performed two times per subject; one time at individual resting PETCO2, the other at an isocapnic PETCO2 baseline at 40 mm Hg. Scanning at 40 mm Hg PETCO2 causes a reduction in CVR as well as a reduction in the amplitude of hemodynamic changes evoked by bilateral finger-tapping. This study highlights the importance how the baseline PETCO2 level is influencing neuroimaging results. (e) Correlation maps showing region-dependent influences of cardiorespiratory activity on brain hemodynamics.45 The correlations with cardiac pulsatility was determined with the RETROICOR method, HR and respiration influences with a scan-specific models. Note the large correlations of HR and respiration with hemodynamic fluctuations in the frontal and occipital lobes. Subfigures (a), (d) and (e) modified from Williams et al.,46 van Niftrik et al.,49 and Kassinopoulos and Mitsis.45 Subfigures (b) and (c) redrawn from Catchlove et al.47 and Miller et al.48",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272976-3-NPh-009-030801-g005.jpg"
} | 009397 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "Comparison between different techniques to remove confounding physiological factors in resting-state fNIRS measurements. Shown are the findings of Abdalmalak et al.99 They investigated the impact of applying different physiological interference reduction methods on detecting resting-state functional brain networks. Depicted are the functional brain networks determined using raw data, with short-channel regression, with short-channel and systemic physiology (HR, MAP, and PETCO2) regression, and with PCA-based regression. A whole-head fNIRS montage was used with 121 long-channels (SDS: 3 cm) and eight short-channels (SDS: 0.8 cm). (a) Group-averages and (b) single-subject variability (examples of three subjects; seed: auditory network). The single-subject analysis shows that there is a more distinct difference between the PCA-based regression and the short-channel and systemic physiology regression compared to the group-level analysis. The study shows the necessity and usefulness of the SPA-fNIRS to determine functional resting-state networks. Subfigures (a) and (b) modified from Abdalmalak et al.99",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272976-8-NPh-009-030801-g009.jpg"
} | 009398 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
|
{
"caption": "The resected segment of the ischaemic small bowel.",
"subfigure_path": "/datasets/PMC-15M/filtered_biomedica/filtered_v4/subfigures_final/subfig_0_filelist_commercial_batch_124_50-PMC9272985-1-cureus-0014-00000025704-i06.jpg"
} | 009399 | hf://datasets/vector-institute/open-pmc-18m@6109d453e9b8e2de3564869941b2e622faddd8d3/data_00028.tar |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.