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56,395,319 | {
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} | Essential oils of the fruits of three cultivars of Amomum subulatum (Family-Zingiberaceae), such as varlangy, seremna and sawney were isolated. Antioxidant potential was determined using 1,1-diphenyl2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) scavenging and FeCl3-reducing models and the presence of 1,8-Cineole was quantified using the developed high performance thin layer chromatography (HPTLC) method. In the DPPH scavenging model, the IC50 value of the essential oil of the seremna, varlangy and sawney were found to be 172.3, 216.9 and 274.3 μg/ml, respectively, while in the ABTS scavenging model, the IC50 value of the seremna, varlangy and sawney were found to be 27.96, 31.34 and 32.49 μg/ml respectively. The antioxidant power of the FeCl3 reducing model, the absorbance value of the essential oil of the seremna was found comparatively higher than the essential oils of varlangy and sawney. The content of 1,8-cineole was determined by the developed HPTLC densitometric method, and the value of the percentage (mean ± SD, % w/w) content of the essential oils of the seremna, varlangy and sawney were found to be 69.59 ± 1.45%, 48.78 ± 3.21 and 47.84 ± 1.76 respectively. The highest antioxidant value of seremna cultivar may be due to the presence of high content of 1, 8-cineole. The HPTLC method, therefore confirms that monoterpene 1,8-cineole is the main antioxidant compound present in the fruits of A. subulatum. | 2022-10-28T09:15:32.248Z |
201,218,915 | {
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"DOI": "10.4271/2019-24-0026",
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"url": "https://repository.kaust.edu.sa/bitstream/10754/663831/1/19ICENA-0282%20v6-revised-final.pdf"
} | This study examined the octane boosting effects of γ-valerolactone, a fuel derived from lignocellulosic biomass, under Homogeneous Charge Compression Ignition (HCCI) combustion mode. The experiments were performed in a Cooperative Fuel Research (CFR) engine under four sets of conditions defined by the combinations of intake temperatures and rotation speed. Octane boosting effects were rated with FACE (Fuel for Advanced Combustion Engine) J gasoline as a base fuel. Due to the non-miscibility of γ-valerolactone into FACE J, a new approach was proposed in which the octane boosting effect of a mixture comprised up of two-third γ-valerolactone and one-third ethanol was investigated. To evaluate the effect of γ-valerolactone, the octane boosting effect of pure ethanol into FACE J was also investigated such that comparison can be drawn. Further attempts were made to extract the octane boosting effects of pure γ-valerolactone. For convenience, both volumetric and molar approaches were considered to rationalize the experimental results. The results showed that γ-valerolactone is a good octane booster, and that it possesses higher octane enhancement potential than ethanol for a low volume fraction in FACE J. In contrary, opposite trends were observed for the higher volume fractions of γ-valerolactone. Finally, the assessment of the blending octane number for pure γ-valerolactone revealed nonlinear octane boosting effects. | 2022-09-04T13:47:14.949Z |
25,820,135 | {
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"DOI": "10.1021/jp3039187",
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} | Molecular dynamics simulations are used to investigate heterogeneous ice nucleation in model systems where an electric field acts on water molecules within 10-20 Å of a surface. Two different water models (the six-site and TIP4P/Ice models) are considered, and in both cases, it is shown that a surface field can serve as a very effective ice nucleation catalyst in supercooled water. Ice with a ferroelectric cubic structure nucleates near the surface, and dipole disordered cubic ice grows outward from the surface layer. We examine the influences of temperature and two important field parameters, the field strength and distance from the surface over which it acts, on the ice nucleation process. For the six-site model, the highest temperature where we observe field-induced ice nucleation is 280 K, and for TIP4P/Ice 270 K (note that the estimated normal freezing points of the six-site and TIP4P/Ice models are ∼289 and ∼270 K, respectively). The minimum electric field strength required to nucleate ice depends a little on how far the field extends from the surface. If it extends 20 Å, then a field strength of 1.5 × 10(9) V/m is effective for both models. If the field extent is 10 Å, then stronger fields are required (2.5 × 10(9) V/m for TIP4P/Ice and 3.5 × 10(9) V/m for the six-site model). Our results demonstrate that fields of realistic strength, that act only over a narrow surface region, can effectively nucleate ice at temperatures not far below the freezing point. This further supports the possibility that local electric fields can be a significant factor influencing heterogeneous ice nucleation in physical situations. We would expect this to be especially relevant for ice nuclei with very rough surfaces where one would expect local fields of varying strength and direction. | 2022-12-19T12:23:56.514Z |
154,809,212 | {
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"DOI": "10.2139/ssrn.1883821",
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"url": "https://scholarship.law.upenn.edu/cgi/viewcontent.cgi?article=1377&context=faculty_scholarship"
} | The Leahy-Smith America Invents Act, the most significant patent law reform effort in two generations, has a dark side: It seems likely to decrease the patenting behavior of small inventors, a category which occupies special significance in American innovation history. In this paper we empirically predict the effects of the major change in the law: a shift in the patent priority rules from the United States’ traditional “first-to-invent” system to the predominant “first-to-file” system. While there has been some theoretical work on this topic, we use the Canadian experience with a similar change as a natural experiment to shed the first empirical light on the question.Our analysis uses a difference-in-difference framework to estimate the impact of the Canadian law change on small inventors. Using data on all patents granted by the Canadian Intellectual Property Office and the US Patent and Trademark Office, we find a significant drop in the fraction of patents granted to small inventors in Canada coincident with the implementation of first-to-file. We also find no measurable changes in patent quality and perform several additional analyses to rule out alternative explanations. While the net welfare impact that can be expected from a shift to first-to-file is unclear, our results do reveal that, contrary to the conventional wisdom, the March 2013 implementation of a first-to-file rule in the U.S. is likely to result in reduced patenting behavior by individual inventors. | 2022-12-28T23:18:24.925Z |
96,471,598 | {
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"DOI": "10.1111/J.1468-0270.1986.TB01763.X",
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} | Mr Roy Hattersley has called for the establishment of a national investment bank to secure funds for economic growth in Britain. Forrest Capie, of the City University Business School, and G.R. Steele, Lecfurer in Economics of the University of Lancaster, examine, in two complementary articles, the practical obstacles, logical inconsistencies and objectionable morality of Mr Hattersley's proposal. | 2022-02-10T14:25:56.246Z |
251,707,709 | {
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"DOI": "10.1364/oe.464449",
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"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.1364/oe.464449"
} | A new simulation model for light transmission of broad-spectrum artificial light in case 1 water is introduced in this paper. The model simulates spectrum changes of fishing lamps due to absorption and scattering of seawater. According to underwater spectrum changes, this model restores the light field generated by fishing lamps and demonstrates the distribution of visual stimuli to marine organisms. The accuracy of the transmission model is verified by comparing it with experimental data. In addition, by comparing the simulation results of light transmission models of different fishing lamps in seawater of various fishing grounds, we investigate why current light-emitting diode (LED) lights are not as effective as metal halide (MH) lamps for light fishing. Lastly, suggestions for future optimization of LED fishing lamps in terms of light distribution design and spectrum configuration are provided. | 2022-10-16T07:26:52.862Z |
132,697,453 | {
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"DOI": "10.1108/S2042-1443(2010)0000003018",
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} | The chapter discusses the effects of climate change on tourism development in Estonia, Latvia, and Lithuania by combining these countries into a single Eastern Baltic Sea Region. The chapter explores the current situation and investigates the trends that will affect the economic development if the present climate conditions are situated in historical context. The first part discusses how destinations can be better managed if they are informed by the scholarship on ecological modernization and updated by a coevolutionary approach to climate change. This discussion proceeds with an analysis of the impact climate change has on tourism following different scenarios of current and future climate conditions. The development of tourism in the Baltic countries is then assessed with references to sustainable development. Overall the chapter demonstrates how destinations can cope with the changing preferences of tourists even in the face of highly unpredictable climatic developments. | 2022-12-11T05:50:34.248Z |
145,158,282 | {
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"ArXiv": null,
"DOI": "10.1515/1944-2866.1162",
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} | This article looks at how patients with pancreatic cancer use the Internet, and considers its potential negative effects for people with a life threatening illness. We designed a qualitative study using semi-structured interviews collected by maximum variation sampling. Respondents were recruited from all over the UK in 2009/10. We interviewed 32 people with pancreatic cancer and eight relatives/carers of people who had recently died of pancreatic cancer. In contrast to a similar study we undertook in 2004, we found that the people interviewed in 2009/10 talked about using the Internet for health information as if it were a routine and unremarkable part of life. Patients gave few examples of harm from using the Internet, or of damage caused to their relationships with health professionals. We also found that patients and family carers were using a strategy to handle alarming information found online, with patients asking partners and family to filter what they found. In conclusion, concerns about serious negative effects of using the Internet for health information may be ill-founded, even when the Internet is used by patients with serious life threatening illness. Clinicians may worry that people will find unwanted or contradictory information, but it is probably counter-productive to try to steer people away from the web. Similarly, policy makers have focused on regulating the factual content of information on the web, but we found that it was the consequences of stumbling on factually correct, yet unwelcome, information that concerned the patients and their families in this study. Good practice guidelines and quality markers for health information may need to pay more attention to website design and user routing as well as factual content. © 2012 Policy Studies Organization. | 2022-12-20T04:17:45.362Z |
28,555,896 | {
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"ArXiv": null,
"DOI": "10.1079/PNS19690007",
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} | 35 malnourished-looking baby, who has been affected in the last few weeks of pregnancy only, and the short relatively well-proportioned baby with rubella syndrome whose growth was retarded in the first trimester. The long thin baby has a relatively normal number of thin cells whereas the rubella baby has a low cell population in organs throughout his body. l‘hese two situations are not, however, mutually exclusive so that a baby whose growth has been retarded for months rather than weeks may present some reduction in cell population in addition to a reduced cell size. In any individual case the infant’s potential for physical and mental development is likely to be limited by the extent to which the cell population of different organs has been permanently depleted. Nutrition of the foetus and the newly born | 2022-12-21T10:21:04.855Z |
129,761,655 | {
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"DOI": "10.1029/95JB00757",
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} | Elastic waves velocities were measured in the laboratory on homogeneous limestones in three different frequency ranges with varying water saturations (Sw). Measurements at frequencies of approximately 1 kHz were obtained using large (1-m length) resonant bars. The conventional pulse transmission technique was used to measure the samples at 50 kHz and 500 kHz. In order to study the influence of the fluid distribution we used two different saturation methods: drying and depressurization. Using a computerized tomography scan to image fluid distribution, we found that during depressurization, saturation was highly homogeneous at the millimetric scale at all saturations. In contrast, during the drying, heterogeneous saturation was observed at high water saturation levels. Results from elastic wave propagation show that compressional and extensional velocities are sensitive to the saturation technique at high water saturation level. Furthermore, the dependence of velocity upon saturation technique is frequency dependent, and dispersion is greatest at high saturations. We attribute this behavior to a scale effect that varies with the size of heterogeneities of the rock and with the wavelength. In addition to global and local flow mechanisms it seems necessary to include a “path dispersion” effect to explain the amount of velocity dispersion observed. For shear waves the experimental results show little variation of the velocity with frequency and very little with fluid distribution. | 2022-12-29T21:26:29.989Z |
121,683,172 | {
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"DOI": "10.1070/SM2011v202n11ABEH004200",
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} | On the Engel group a nilpotent sub-Riemannian problem is considered, a 4-dimensional optimal control problem with a 2-dimensional linear control and an integral cost functional. It arises as a nilpotent approximation to nonholonomic systems with 2-dimensional control in a 4-dimensional space (for example, a system describing the navigation of a mobile robot with trailer). A parametrization of extremal trajectories by Jacobi functions is obtained. A discrete symmetry group and its fixed points, which are Maxwell points, are described. An estimate for the cut time (the time of the loss of optimality) on extremal trajectories is derived on this basis. Bibliography: 25 titles. | 2022-12-31T18:46:55.209Z |
219,040,398 | {
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"DOI": "10.25192/ISSN.1982-0496.RDFD.V25I11506",
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} | O presente estudo tem por objetivo analisar a cidadania e o desenvolvimento do meio rural brasileiro a partir da elaboracao de politicas publicas direcionadas para este setor, especialmente aquelas elaboradas para a agricultura familiar. A cidadania no meio rural pode ser visualizada a partir da acao comunicativa orientada para o consenso mutuo, realizada no mundo da vida do agricultor familiar, isto e, em sua unidade de producao, sendo possivel verificar o inicio da criacao de politicas publicas voltadas para o meio rural, havendo, portanto, uma estreita ligacao entre as nocoes de desenvolvimento rural e cidadania. Para a obtencao dos objetivos pretendidos, o presente estudo necessitou realizar uma conexao com o pensamento do filosofo Jurgen Habermas, utilizando seus conceitos e nocoes sobre o agir comunicativo voltado para o entendimento mutuo, bem como sua ideia de mundo da vida. Ao final, a pesquisa denota a importância das politicas publicas direcionadas para a agricultura familiar para a efetivacao do desenvolvimento e da cidadania do meio rural brasileiro, os quais sao concretizados quando da elaboracao de politicas publicas emancipatorias e nao meramente politicas publicas de subordinacao, na medida em que sao formuladas, pensadas e aplicadas a partir do consenso mutuo entre os atores sociais rurais promotores do real desenvolvimento, qual seja, o agricultor familiar. | 2022-01-27T11:38:21.511Z |
125,744,755 | {
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"DOI": "10.2312/GFZ.B103-11036",
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} | The magnetic field of the Earth varies in space and time. Geomagnetism as research area that aims to describe and understand the sources of these variations is supported by two pillars: first, regular high-precision measurements in the global network of magnetic observatories and repeat stations are necessary to register the field and its variations at all. Second, mathematical methods are required in order to extract magnetic field models from this large data set. Methods applied to data offer insights in the mechanisms generating the magnetic field.
This thesis covers both subjects. In a first part, following the description of the state of the art in observatory instrumentation, I explain in detail two instruments that have the potential to streamline the classical procedures: The Geomagnetic AUtomated SyStem GAUSS paves the way to automated absolute measurements, up to now only possible manually. The newly developed DI3 technique improves and simplifies the standard manual measurements significantly and thus reduces the requirements placed on observers.
The second part deals with the mathematical tools available for geomagnetic field modelling. I focus on harmonic splines that can be derived from the classical approach of spherical harmonics. These base functions are interpolatory and have a localised shape while satisfying Laplaces equation. Hence, they are applicable to fit data regionally or globally.
The harmonic splines are used with a data set made of repeat station and observatory measurements from Southern Africa. This region is of special interest because the field intensity is very low and and both spatial and temporal field gradients exist. Subdivided into an analysis of ancient (years 1961-2001) and recent (2005-2009) data, two continuous regional field models SAMS and X-SAMS are derived. From the analysis of the field models, a better understanding of the field behaviour is gained.
Finally, the harmonic splines are used in a case study on globally distributed secular variation data. Rotating the data set in a system of coordinates aligned with the dipole axis and modelling it with the harmonic splines reveals the external origin of observed fast variations. | 2022-01-27T18:09:09.008Z |
165,955,598 | {
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"DOI": "10.4000/books.septentrion.48656",
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"url": "https://doi.org/10.4000/books.septentrion.48656"
} | Resumen – En la abundante producción historiográfica dedicada a Gregorio Magno, no se ha profundizado suficientemente en el estudio de los oficiales militares que desem� peñan sus funciones durante su pontificado, y esto resulta sorprendente dada la impor� tancia del ejército en una Italia gravemente amenazada por el peligro longobardo. Los datos que pueden extraerse del Registrum nos permiten discernir diversos aspectos de la administración bizantina en la Península italiana, en particular de la organización y las funciones de los mandos militares en tiempos de Gregorio. A través de su epistolario, podemos establecer una prosopografía específica que hace posible esbozar una imagen acerca de la composición de los oficiales del Imperio : su origen étnico, su distribución y las diversas funciones que desarrollan, sean estrictamente bélicas, o bien policiales, civiles e incluso religiosas. | 2022-02-08T19:43:09.790Z |
41,092,015 | {
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"DOI": "10.1097/00075197-200309000-00012",
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} | Purpose of reviewThe provision of nutrition to patients with advanced digestive cancer, especially those with obstruction, has been an issue discussed by physicians, administrators and patients themselves. There is no real consensus about this topic, perhaps because of the fact that this discussion involves medical, emotional, ethical, economical and legal considerations that are not easily encompassed by any single decision. On the other hand, the quality of life or survival of these patients must be thoroughly evaluated because one of the basic tenets of medicine has always been ‘primum non nocere’ (‘above all, do not harm’). Quality of life itself is a complicated concept because it has no specific definition and varies with each individual and depends upon his/her actual living reality, past experiences, future hopes, dreams and even ambitions. Recent findingsRecent studies have presented controversial results when evaluating the benefits of providing nutritional therapy to patients with advanced digestive cancer with obstruction. Therefore, decision-making should be addressed on an individual basis, but at the same time should be based on defined protocols within each institution. A key factor to be considered is communication among all those involved in the process; most important is the role of the patient and his/her family, who should be able to communicate their feelings, concerns and ethical principles. SummaryNutritional therapy in advanced digestive cancer is an instrument that should be evaluated as an extra tool that may offer improved quality of life to those with obstruction, despite the associated increased costs. However, in this delicate matter, our decisions should not be driven by increased pressure by medical system administrators to limit financial expenditure. | 2022-09-03T12:41:40.395Z |
621,564 | {
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} | This is an editorial commentary in response to the Anderson and Spiers (2014), “Alone in Eden: Care Aides’ Perceptions of Consistent Assignments,” published by the Western Journal of Nursing Research on February 11, 2014. We respect the authors for sharing the research completed in the five nursing homes discussed in this article in relationship to the care aides and consistent assignments. Our intention with this commentary is to provide additional information based on research and the experiences of the authors of this commentary. There have been many articles written regarding the need for the paradigm shift to consistent assignments and how to accomplish this change within the medical model of care in a long-term care setting. This shift did not necessarily require a new model of care, but rather a shift in the philosophy of care and who was deemed as important to that philosophy of care. The Eden Alternative is a principle-based philosophy of care that shifts people and organizations away from the medical model of care, putting the person receiving services in the center of the care philosophy. This article was intended to focus on the experiences of certain nursing home employees related to The Eden Alternative philosophy of care. Studies have shown when Culture Change is embraced in the long-term care setting; people living in these settings have a better quality of life (Elliot, n.d.; | 2022-09-10T12:35:50.036Z |
46,830,848 | {
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"DOI": "10.1159/000207411",
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} | The erythroid and granulocytic repopulating ability of rat bone marrow has been measured after daily administration of three alkylating agents: dimethylmyleran, busulphan and cyclophosphamide. Three different patterns of response were observed. The results emphasize the variability of the response of haemopoietic tissue to repeated administration of different cytotoxic drugs and provide further evidence that erythroid and granulocytic repopulating assays measure different populations of precursor cells. | 2022-09-14T05:48:50.054Z |
250,508,363 | {
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"DOI": "10.1109/gol53975.2022.9820165",
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} | There is rising adoption of traceability solutions in blockchain-based applications. Blockchain appropriately meets supply chain using traceable distributed records. We integrate a bibliometric study (869 articles) and a lexicometric study (135 articles) analyzing knowledge paths and communities based on previous research to guide its development. The bibliometrics illustrates the holistic evolution with co-citation analysis: influential researchers and countries, discipline composition, knowledge development trends, and emerging frontiers. The lexicometric identifies the concept structure of epistemic communities with a textual approach. From the knowledge graphs, we found that blockchain traceability research began in 2016 and emerged a surge from 2019. There are three chronological phases: 2016-2017 technological embryonic stage, 2018-2019 emerging establishment stage, 2020-Now ecological optimization stage. Blockchain traceability interconnects with IoT for intelligent tracking. It mainly applies in food and agriculture supply chain nowadays, waiting for further large-scale application in automobile manufacture and carbon emission. Blockchain and supply chain mutually transform as sensemaking theory. Traceability solutions have been popularized in business scenarios. | 2022-09-28T11:54:35.676Z |
239,850,284 | {
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"DOI": "10.1017/S1431927621012940",
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} | Abstract Laser-assisted atom probe tomography (APT) is a relatively new, powerful technique for sub-nanometric mineral and biomineral analysis. However, the laser-assisted APT analysis of highly anisotropic and chemically diverse minerals, such as phyllosilicates, may prove especially challenging due to the complex interaction between the crystal structure and the laser pulse upon applying a high electric field. Micas are a representative group of nonswelling clay minerals of relevance to a number of scientific and technological fields. In this study, a Mg-rich biotite was analyzed by APT to generate preliminary data on nonisotropic minerals and to investigate the effect of the crystallographic orientation on mica chemical composition and structure estimation. The difference in results obtained for specimens extracted from the (001) and (hk0) mica surfaces indicate the importance of both experimental parameters and the crystallography. Anisotropy of mica has a strong influence on the physicochemical properties of the mineral during field evaporation and the interpretation of APT data. The promising results obtained in the present study open the way to future innovative APT applications on mica and clay minerals and contribute to the general discussion on the challenges for the analysis of geomaterials by atom probe tomography. | 2022-10-28T00:56:22.689Z |
240,548,392 | {
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"DOI": "10.30742/JISA.V21I1.1345",
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} | Komoditas holtikultura yang mempunyai nilai ekonomi dan harga jual tinggi adalah Cabai rawit (Capsicum frutescens L). Menurut para ahli, komoditas holtikultura pada komoditi cabai rawit memiliki tingkat kebutuhan yang tinggi seperti sebagai bumbu masakan, industry makanan dan obat-obatan. Semua itu meningkat juga oleh kenaikan tingkat permintaan yang komoditi cabai rawit pernah mengalami harga jual yang fluktuasi paling tinggi di Indonesia. Maka dari itu Indonesia harus mengembangkan produksi dan produktivitas cabai rawit agar semakin meningkat. Tujuan penelitian ini adalah (1) Menganalisis faktor-faktor yang mempengaruhi produksi cabai rawit di Indonesia, (2) Menganalisis faktor-faktor yang mempengaruhi produktivitas cabai rawit di Indonesia.Data yang digunakan adalah data sekunder dan sumber data diperoleh melalui Basis Data dan Kementrian Pertanian. Metode analisis yang digunakan adalah metode Analisis regresi linier berganda. Hasil uji hipotesis Pada uji R square faktor produksi 81,6% dan uji F sebesar 13,292. Secara parsial (Uji t) menunjukkan pengaruh signifikan antara luas lahan dan penting terhadap produksi cabai rawit di Indonesia, dan tidak ada pengaruh signiftikan antara ekspor dan konsumsi terhadap produksi cabai rawit di Indonesia. Selanjutnya faktor produktivitas pada uji R square sebesar 69,4% dan ujia F sebesar 10.224. Dalam pengujian secara parsial (Uji t) menunjukkan adanya pengaruh yang signifikan terhadap lahan terhadap produktivitas cabai rawit di Indonesia.Metode analisis yang digunakan adalah metode Analisis regresi linier berganda. Hasil uji hipotesis Pada uji R square faktor produksi 81,6% dan uji F sebesar 13,292. Secara parsial (Uji t) menunjukkan pengaruh signifikan antara luas lahan dan penting terhadap produksi cabai rawit di Indonesia, dan tidak ada pengaruh signiftikan antara ekspor dan konsumsi terhadap produksi cabai rawit di Indonesia. Selanjutnya faktor produktivitas pada uji R square sebesar 69,4% dan ujia F sebesar 10.224. Dalam pengujian secara parsial (Uji t) menunjukkan adanya pengaruh yang signifikan luas lahan terhadap produktivitas cabai rawit di Indonesia. Metode analisis yang digunakan adalah metode Analisis regresi linier berganda. Hasil uji hipotesis Pada uji R square faktor produksi 81,6% dan uji F sebesar 13,292. Secara parsial (Uji t) menunjukkan pengaruh signifikan antara luas lahan dan penting terhadap produksi cabai rawit di Indonesia, dan tidak ada pengaruh signiftikan antara ekspor dan konsumsi terhadap produksi cabai rawit di Indonesia. Selanjutnya faktor produktivitas pada uji R square sebesar 69,4% dan ujia F sebesar 10.224. Dalam pengujian secara parsial (Uji t) menunjukkan adanya pengaruh yang signifikan luas lahan terhadap produktivitas cabai rawit di Indonesia. Secara parsial (Uji t) menunjukkan pengaruh signifikan antara luas lahan dan penting terhadap produksi cabai rawit di Indonesia, dan tidak ada pengaruh signiftikan antara ekspor dan konsumsi terhadap produksi cabai rawit di Indonesia. Selanjutnya faktor produktivitas pada uji R square sebesar 69,4% dan ujia F sebesar 10.224. Dalam pengujian secara parsial (Uji t) menunjukkan adanya pengaruh yang signifikan luas lahan terhadap produktivitas cabai rawit di Indonesia. Secara parsial (Uji t) menunjukkan pengaruh signifikan antara luas lahan dan penting terhadap produksi cabai rawit di Indonesia, dan tidak ada pengaruh signiftikan antara ekspor dan konsumsi terhadap produksi cabai rawit di Indonesia. Selanjutnya faktor produktivitas pada uji R square sebesar 69,4% dan ujia F sebesar 10.224. Dalam pengujian secara parsial (Uji t) menunjukkan adanya pengaruh yang signifikan luas lahan terhadap produktivitas cabai rawit di Indonesia.Kata Kunci: Produksi, pengaruh, Produkstivitas, Impor, Ekspor, regresi linier berganda | 2022-11-06T16:56:15.995Z |
243,246,148 | {
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} | <jats:sec sec-type="headline">
<jats:title content-type="abstract-subheading">Headline</jats:title>
<jats:p>LIBYA: UN's dialogue outcome could trigger clashes</jats:p>
</jats:sec> | 2022-01-24T18:58:58.473Z |
57,794,740 | {
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} | A new proposed model has been implemented to guarantee the required voice quality based on the available network resources. Although, the proposed model is so simple from the routers side, it is somehow complex from the host side due to the input analyzing process. On the other hand, the QBone (quality of service backbone) model moves the complexity to the router side. Practically, the QBone model does not face any success because most of the users are not willing to pay much money to have voice sessions across the Internet. So, the proposed model not only guarantees the voice quality but also saves the network resources (up to 74% of the consumed bandwidth). | 2022-02-11T17:46:07.762Z |
196,775,095 | {
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"DOI": "10.1002/CHIN.201432161",
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} | Triphenylphosphine-promoted isomerization of the title compounds (I) results in formation of a mixture of 5-oxohexenoates (II) and (III) while DABCO as promotor gives lactones (V) as products. | 2022-06-23T19:21:18.614Z |
133,577,054 | {
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} | This research is dedicated to issues, related to determining the legal principles of management in the sphere of water protection, use and rehabilitation of water resources. It considers the legislative acts, determining competences of the related state authorities . The research provides recommendations on improving appropriate legislation. | 2022-12-30T01:01:57.162Z |
24,445,464 | {
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} | A method for controlling microsphere particle size by regulating the ratio of polymer to solvent concentration and volume fraction, for an emulsion-solvent removal type of microencapsulation system, has been investigated. Viscosity of the external phase was kept constant by using light mineral oil in all experiments. Viscosity of the polymer solution, the internal phase, was modified by changing the ratio of the polymer to solvent concentration. Microspheres were obtained by adding the internal phase to the external phase and stirring the mixture for 30 min. A non-solvent was then added to the system to harden the polymer and recover the microspheres. Polymer concentration was modified by adding extra solvent to the mineral oil, just before the addition of the internal phase and also by adding extra solvent to the polymer phase. Similar, but not identical, results were obtained in both of these systems. A plot of particle size versus polymer to the solvent ratio resulted in sigmoidal curves. The term solvent means the solvent available to the polymer after mixing with mineral oil. A separate curve was obtained for each polymer concentration used in the experiments. When the internal phase volume fraction was incorporated as a variable in the plot of particle size, the three sigmoidal curves merged into a single curve, irrespective of the polymer concentration. The equation developed for controlling the particle size, as a function of polymer and solvent concentration and phase volume ratio, also was tested in systems that contained tartrazine as a model drug. Dissolution experiments were carried out and dissolution rate was correlated to particle size. Microspheres size was controlled by polymer and solvent concentration and phase volume ratio. | 2022-02-12T18:40:40.371Z |
207,005,197 | {
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} | Sulfur detection. Antek Instruments, Inc., introduces the Model 8040 Sulfur-Specific HPLC Detector (HPLCSCD) capable of quantitating unknown compounds without using the unknown as a reference. Its equimolar response allows sulfur detection using any readily available sulfur standard. The 8040 is ideal for thermally labile samples or those too viscous for injection into a GC detector. It also easily configures to supercritical fluid chromatography. 120 | 2022-07-01T02:46:33.065Z |
144,500,762 | {
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} | DIRECTIONS: Read the following three passages from "Teaching Story." After carefully reading each passage, select the best answer for each multiple-choice item. You have 15 minutes to complete the test. Your performance will assess your understanding of what it means to be a teacher.Passage ICharlie. Such a happy-sad kid. He came for the first three days of school, but this is the first time I've seen him in two weeks. He's escorted by a security guard, 15 minutes late. Opening the door, I say, "Hey, hey Charlie! Glad to see you back."He turns to look at me, his eyebrows raised in surprise or confrontation-I've only seen him a few times, so I'm unsure. My gut, though, suggests he's astonished that I'm greeting him, that I'm happy to see him, that I don't immediately harass him for arriving tardy or missing class. I grin and earn a slight smile back that fails to reach his eyes and, in that moment, while I'm sidestepping to let him pass, take in the fact that his honeyed eyes swim in a tide of bloodshot white. He shuffles over to his seat and pops in his earbuds beneath an over-sized, red hoodie. Tuned in? Tuned out? I don't know.It's been just a few moments, but it's been enough: One student has climbed onto the table in the center of the room. He reclines inappropriately on his side like a lingerie model and twirls an eyelash curler around an index finger, blinking at me slowly. Deliberately. As most of the rest of the class hoots and takes pictures, placing bets on my response, I appreciate that today a flowered headband festoons his hair. I've watched him cut, pin, comb, curl, dye, and cry over that hair. His attempts to control it always fail. It will be what it is. I watch one more bleached-out tendril of frizz escape its plastic, half-moon prison and, without missing a beat, I open my book and say, "Oh, Jon, get down before you hurt yourself.""Awwww!" responds most of the class, hoping for a larger reaction. "Incidentally, your eyes really POP today."And they do. That eyelash curler has worked wonders.And that did it. The class starts to really lose it.I'm certain Snapchat, Twitter, Facebook, and whatever other media students access on their handheld space machines crash under the tsunami of posts.Jon bows and, singing all the s's together fluidly in "Thanksss Mssss. LeSsssage," he leaps off the table. Off the stage. He gifts his headband for a handshake, his eyelash curler for a hug, and his throne on the table for a seat in his desk. Jon shines. He is Sally Fields and the class likes him. They really like him. Their deluge of applause and laughter crescendos and crests.As I try to call the students' attention back together for a discussion about our whole-class book, I see Charlie put his head down. Now I also see that he doesn't have the backpack I got him, or any of the other supplies a fellow teacher and I scrounged around for.1.The point of view from which this passage is told is best described as that ofa. an uncaring, unreflective, lazy union thug.b. a student teacher describing a mentor teacher who "succeeds" with "at risk" kids.c. a teacher reflecting on the challenges of helping a student she barely knows.d. an expert, tenured teacher looking back at just a few reasons why she's feeling an overwhelming sense of failure in the teaching profession.2. The most reasonable conclusion to make from the fact that Charlie's "honeyed eyes swim in a tide of bloodshot white" is that hea. is high.b. didn't get enough sleep last night.c. suffers from allergies.d. was crying.3. It can be reasonably inferred that which of the following steps should next be taken?a. Ignore Charlie and continue on with the class.b. Check in to see if Charlie needs to go to the nurse and tell him you're glad to see him again.c. Ask Charlie what happened to the stuff you got him. … | 2022-07-10T19:59:21.863Z |
8,277,674 | {
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} | The external eye can be considered a passive dust sampler. Foreign material deposited in the conjunctival cul-de-sac becomes enclosed by mucous fibrils. The fibrils adhere to the conjunctival mucous thread. Hence, by removing the mucus, one can study, eg, man-made mineral fibers deposited in the eye. In this study a simple method for this purpose has been developed, and the sampling characteristics of the eye for nonrespirable fibers is described. The numbers of nonrespirable fibers accumulated in the eyes correlated with the total dust exposure dose (correlation coefficient r = 0.92) and with the nonrespirable fiber exposure dose (r = 0.82). There was no correlation between the airborne fiber concentration and the number of fibers in the mucous thread alone. | 2022-09-09T23:45:43.586Z |
9,988,195 | {
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} | By a topological semiring we mean a Hausdorff space S together with two continuous associative operations on S such that one (called multiplication) distributes across the other (called addition). That is, we insist that x(y-{-z)=xy-\-xz and (x-\-y)z = xz-\-yz for all x, y, and z in 5. Note that, in contrast to the purely algebraic situation, we do not postulate the existence of an additive identity which is a multiplicative zero. In this note we point out a rather weak multiplicative condition under which each additive subgroup of a compact semiring is totally disconnected. We also give several corollaries and examples. Following the notation current in topological semigroups we let •f^[ + ](e) represent the maximal additive subgroup containing an additive idempotent e. Similarly H[-](f) will denote the maximal multiplicative group of a multiplicative idempotent /. The minimal closed additive or multiplicative semigroup containing x is denoted by r[+](x) or T[](x) respectively. By £[+] or £[• ] we mean the collection of additive or multiplicative idempotents. Finally A * represents the topological closure of A. For references on the properties of these sets the reader may see [l]. | 2022-09-12T23:31:12.416Z |
114,789,622 | {
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} | A modified route to synthesize graphene flakes is proposed using the Chemical Vapor Deposition (CVD) technique, by using copper substrates as supports. The carbon source used was ethanol, the synthesis temperature was 950°C and the pressure was controlled along the whole process. In this CVD synthesis process the incorporation of the carbon source was produced at low pressure and 950°C inducing the appearance of a plasma blue flash inside the quartz tube. Apparently, the presence of this plasma blue flash is required for obtaining graphene flakes. The synthesized graphene was characterized by different techniques, showing the presence of non-oxidized graphene with high purity. | 2022-12-12T23:00:40.252Z |
136,886,273 | {
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} | Lasers are currently limited in their ability to remove hard tissue. Furthermore, many laser systems, such as the long pulse infrared lasers used to ablate bone or hard dental tissue, also generate unacceptable heat levels and cause collateral tissue damage. Ultrashort pulse lasers, however, are highly efficient, quiet, and relatively free of charge. With recent developments now allowing operation at high pulse repetition rates, ultrashort pulse systems can yield significant material volume removal which can potentially match or even exceed conventional technology while still maintaining the minimal collateral damage characteristics. In this paper, the interaction characteristics of two pulse regimes with enamel and dentin: 350 fs pulse ablation of hard dental tissues is compared to the interaction with one nanosecond pulses. Ablation rates were characterized and surface morphology, and structure were evaluated using a scanning electron microscope. | 2022-12-16T14:21:21.032Z |
85,986,757 | {
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} | Abstract Two previously unknown male treehoppers of Cladonota (Lecythifera) bulbosa Flynn and C. (L.) hoffmanni (Peláez) from Mexico are described, compared, and illustrated. | 2022-02-10T22:47:36.159Z |
78,310,736 | {
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} | Non-Hodgkin's lymphomas (NHLs) embody a diverse group of malignancies that originate from the lymphoid system. NHL often exhibit in an extranodal pattern, pertaining to the head and neck region. Intraoral sites are much less frequent, accounting for approximately 3.5% of all oral malignancies. Although the exact cause of NHL still remains inconspicuous, however, research has focused on some factors that may contribute to the development of lymphoma, including genetic factors, impaired immune system and viruses, such as HIV or EBV. Clinically, the bony lesion may present as localized or diffuse swelling, with low-grade pain, sweating, unexplained weight loss, fever, etc. Radiographically, these lesions resemble osteomyelitis or other malignancies creating a diagnostic dilemma. Microscopically, diffused lymphomas consist of large tumor cells with large nuclei that are more than twice the size of lymphocytes which may either exhibit centroblastic or immunoblastic features. Here, we report a rare case of NHL affecting the jaws of a 60-year-old male patient. | 2022-02-11T04:51:44.748Z |
247,629,796 | {
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} | A 62yearold man presented to hospital complaining of 3 days of abdominal discomfort on a background of a monthlong history of fatigue and fevers. He was a past smoker of 12 years and did not use illicit drugs. His medical history was otherwise unremarkable. His abdominal discomfort was epigastric, constant, nonradiating and unaffected by food. There was no associated change in bowel habit. In the emergency department, he was afebrile (37.2°C) but looked unwell. His heart rate was 30 beats per minute, blood pressure was 105/65 mmHg, heart sounds were normal without audible murmurs, and peripheral examination was unremarkable. Jugular venous pressure was normal. He was tender in the epigastrium without guarding or rebound tenderness. Murphy sign was negative. The liver edge was palpable but not tender or pulsatile. Electrocardiography showed complete heart block (Box 1). | 2022-05-01T05:02:50.898Z |
142,112,700 | {
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} | Colonizer and colonized, we all inhabit these death-scarred landscapes. We are here by hope, and we are here by violence. Deborah Bird Rase (1999) The bunya pine has a special meaning for Queenslanders, being endemic to the Bunya Mountains and Blackall Ranges in the South-East corner of the state, with a small stand in North Queensland. The bunya holds particular significance for local Indigenous peoples. They are bound to the tree through custodial rights and obligations and systems of traditional environmental knowledge that incorporate ‘classification …empirical observations of the local environment… [and] self-management that governs resource use’, built up through generations of interaction with the bunya forests. Indigenous groups celebrated their spiritual links to the bunya pine in large seasonal gatherings where they feasted on its edible nuts and performed ceremonies, adjudicated disputes and traded goods. The bunya's majestic height, striking unique silhouette, dark green foliage, unique botanical features and Indigenous associations held a fascination for colonial artists, natural scientists, entrepreneurs and gardeners. Over the years they assumed custodianship of the bunya pine, assimilating it into Western scientific, economic, legal, horticultural, environmental and symbolic systems, which replaced Indigenous custodial rights, obligations and knowledge. The spectacular bunya gatherings were mythologised in colonial writings as mystical, primeval ceremonies and barbaric rituals. Despite ‘fierce and actively hostile tribal resistance’ to colonisation of their lands, Indigenous groups were progressively driven out of the bunya forests. Empty landscapes left by the retreating forests – victims of timber felling and land clearing – came to symbolise the vanishing ceremonies and dwindling Aboriginal populations of South-East Queensland. While surviving Indigenous groups were swept into centralised reserves and settlements from the late nineteenth century, so too the bunya trees were cordoned off in 1908, for their own protection, in Queensland's second national park at the Bunya Mountains, where they stood ‘like the spirits of the departed original Queenslanders, mourning over the days which are forever gone’. | 2022-09-06T18:51:17.582Z |
183,111,077 | {
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} | The aim of this study was to examine whether low vitamin D levels correlate with disease activity in multiple sclerosis (MS). Subjects were participants from Turku, Finland, in the PRISMS Study of interferon beta-1a; 15 patients had received either of the two drug dosages, and 8 had received placebo. From serum specimens that had been drawn every 3 months and at time of relapse, up to 64 weeks, the authors measured serum 25-hydroxyvitamin D (S-25[OH]D), parathyroid hormone, and calcium levels and performed several other clinical chemistry assays in the 23 patients with MS and in 23 healthy laboratory workers (controls).
The authors state that half … | 2022-02-08T12:30:40.811Z |
49,408,130 | {
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} | The remanufacturability is directly determined by the current quality of used parts, and it is highly necessary to accurately predict the remanufacturability of used parts. Based on this, a prediction approach to remanufacturability evaluation of used parts based on extension synthesize evaluation is presented, and domain partition in extension is applied to divide the remanufacturability levels of used parts into reusable level, repairable level, remanufacturable level, and recyclable level according to the damage degree and remanufacturing process. Taken quality characteristics of used parts as prediction indexes, mapping relationship between quality characteristics and remanufacturability levels of used parts by correlation functions. On the basis, matter elements model of remanufacturability levels of used parts is created, and the relevancy between quality characteristics of used parts and remanufacturability levels is determined. Finally, the guide rail of a used TPX6113 boring machine is taken as an example, whose quality characteristics are analyzed to determine its remanufacturability levels by the proposed method. The analytic results coincide very well with the engineering practice in the company of used machine tool remanufacturing. | 2022-02-11T23:03:24.931Z |
243,828,270 | {
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} | The present study was conducted on diversity, distribution, indigenous uses and conservation of economically important Plants in Kalatop-Khajjiar Wildlife Sanctuary, Chamba district, Himachal Pradesh during 2013–2016 which has not been explored so far. A total of 361 economically important species (33 trees, 70 shrubs, 249 herbs and 9 ferns) belonging to 254 genera and 99 families have been recorded. These species are used for medicinal (229 spp.), edible (78 spp.), fodder (15 spp.), fuel (53 spp.), timber (09 spp.), religious (20 spp.) and other species for various other purposes. Of the total species, 150 are native, 211 non - native, 73 near endemic and 01 endemic. These species are distributed between 1870 – 2750m, amsl. Due to habitat degradation, over exploitation and changing environmental conditions, the populations of most of the species are facing threats. Therefore, frequent monitoring of populations of these species in relation to climate change and education and awareness among the local inhabitants and Forest Department Officials are suggested. (NTFPs). | 2022-01-24T21:59:47.585Z |
12,335,743 | {
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} | We experimentally report that the novel “chess board” like 1-D grating structure with optimal period of 800 nm can dramatically increases the J<sub>SC</sub> from 33.7 mA/cm<sup>2</sup> to 38.9 mA/cm<sup>2</sup> compared to the reference solar cell. | 2022-09-07T01:36:24.802Z |
55,891,266 | {
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"url": "https://smartech.gatech.edu/bitstream/1853/33309/1/2009_API_001.pdf"
} | A procedure is described for evaluating particle pinches to be used in interpreting particle diffusion coefficients from measured density and temperature profiles in the edge pedestal of tokamak plasmas. Application to the interpretation of two DIII-D [J. Luxon, Nucl. Fusion 42, 614 (2002)]. discharges yields new information about particle pinches and particle diffusion coefficient profiles in the edge pedestal. | 2022-09-10T08:36:28.541Z |
138,964,593 | {
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} | Short time anneal (STA) experiments were performed in a specially designed system which uses either a bank of Tungsten-Halogen lamps or a moving Mercury arc lamp as the light source. Both STA results were compared with conventional furnace anneal. The Mercury arc lamp anneal is found to be a critical process but optimization for wafer damage free conditions can be achieved. The anneals result in general in a better profile control which is most outspoken for shallow Boron implants while the electrical activation is comparable for all elements to that obtained with Tungsten-Halogen or furnace anneal. | 2022-09-15T00:16:49.748Z |
234,006,192 | {
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} | The quality of health services in health centers and hospitals is strongly influenced by the quality of physical facilities, the types of personnel available, medicines and medical devices, and the process of service delivery. Services are formed based on the principle of Service Quality, namely speed starting from the registration waiting time. According to the 2016 Ministry of Health, the outpatient waiting time of less than 60 minutes can increase customer / patient satisfaction above 90%. Objective to determine the relationship between registration waiting time and patient satisfaction at the outpatient registration site at the Kedaung Barat Public Health Center, Tangerang Regency, 2020. Research design: included an analytical survey with a cross sectional approach. Samples were taken using the Stanley Lameshow formula with unknown proportions, and the total sample size was 196 respondents. Sampling using accidental sampling technique. This study used univariate and bivariate analysis with Chi Square test. Results based on univariate analysis of 196 people, the majority of the waiting time for fast registration was 79.6%, the patients were satisfied by 69.9%. The results of the bivariate analysis with the chi square test found that there was a relationship between registration waiting time and patient satisfaction (p value 0.000) and the closeness value of 2 variables OR = 29.693. Conclusion: from the relationship between waiting time and satisfaction, it is known that fast waiting times have a 30 times chance of making patients feel satisfied. Suggestion for health workers are expected to have commitment and time discipline in providing services according to a predetermined schedule, guidelines and competencies that are owned consistently and in a structured manner | 2022-09-23T00:58:15.398Z |
227,218,186 | {
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"DOI": "10.2478/ast-2020-0014",
"MAG": "3112475533",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://sciendo.com/pdf/10.2478/ast-2020-0014"
} | Abstract Access to potable water is a major problem confronting most developing nations particularly with the overwhelming health burden posed by polluted water and its sources. In this review, studies on the level of contamination of drinking water sources in different geopolitical zones in Nigeria were assessed. The anthropogenic activities eliciting the pollutions were extensively discussed. Overall, the level of Nigeria preparedness in meeting the sustainable development goal number 6 (SDG no 6: to ensure availability and sustainable management of water and sanitation for all) was evaluated. Cogent methods that could enhance the achievement of SDG no. 6 were suggested. From our analysis of published literature, pre- and post- SDG implementation in Nigeria, it is clear that no significant progress has been made in providing potable water for all in Nigeria. All implementing partners must therefore rejig the process to ensure the availability of potable water, in order to achieve the sustainable development goal six. | 2022-11-26T19:25:49.182Z |
210,042,016 | {
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"DOI": "10.1104/pp.19.01445",
"MAG": "2997021279",
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"status": "HYBRID",
"url": "https://academic.oup.com/plphys/article-pdf/182/1/10/38123372/plphys_v182_1_10.pdf"
} | When rays of light enter a plant cell, they find their way to the chlorophyll pigments located in the chloroplast. Chlorophyll molecules are embedded in the light reaction complexes PSI and PSII, which capture and store the energy needed for carbon fixation in the Calvin cycle. In an ideal situation | 2022-12-03T04:44:38.149Z |
84,469,027 | {
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"DOI": "10.1111/J.1440-6055.1979.TB00854.X",
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} | Canonical variate analysis and the generalized distance D2 statistic are useful ways of analyzing within and between variation in species. Little attempt has been made previously to quantify and assess the variation in calyptrate Diptera other than in descriptive terms. In this study, the variation was assessed for 11 species of muscoid Diptera and populations of the five calliphorid species were analyzed in greater detail. Nine morphometric characters of the wing were used. Most of the variance (93%) fell in the first three canonical variates for the species comparison, and emphasised shape attributes, although size was important. In particular, the position of vein R1, humeral vein h, and the discal cell suggested that the sarcophagid flies formed an intermediate group between the calliphorid and muscid flies examined. Size components were more important than shape components within species, and these differences between populations could not be related to a geographic cline. | 2022-12-19T21:34:21.216Z |
12,661,645 | {
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"DOI": "10.1021/OL051629F",
"MAG": "2118301960",
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} | [reaction: see text] An enantioselective gram-scale synthesis of a key dihydroindolizine intermediate for the preparation of myrmicarin alkaloids is described. Key transformations in this convergent approach include a stereospecific palladium-catalyzed N-vinylation of a pyrrole with a vinyl triflate, a copper-catalyzed enantioselective conjugate reduction of a beta-pyrrolyl enoate, and a regioselective Friedel-Crafts reaction. The synthesis of optically active and isomerically pure samples of (4aR)-myrmicarins 215A, 215B, and 217 in addition to their respective C4a-epimers is presented. | 2022-12-23T02:06:26.438Z |
19,189,135 | {
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"DOI": "10.1136/bmj.d7504",
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"status": "HYBRID",
"url": "https://www.bmj.com/content/343/bmj.d7504.full.pdf"
} | Objective To ascertain whether use of the term “obs stable” with respect to the nursing observations is so liberal as to render it meaningless. Design Retrospective study. Setting Three teaching hospitals in London, United Kingdom. Methods We searched progress notes for the current admission of 46 inpatients for entries containing the phrases “obs stable” and “observations stable,” and reviewed the nursing observations recorded during the 24 hour period preceding each entry containing at least one phrase. We calculated the frequency of abnormalities and of persistent abnormalities (defined as occurring in every observation) observed during these 24 hour periods, and the range of observation values over a 24 hour period if at least two observations had been recorded. Results We found at least one entry in 36 (78%) progress notes (95% confidence interval 66% to 90%). Observations in the 24 hours preceding an entry included at least one abnormality for 113 (71%) of 159 cases and at least one persistent abnormality for 31 (19%). The most frequently occurring abnormalities were tachypnoea (respiratory rate ≥20 breaths/min) and hypotension (systolic blood pressure <100 mm Hg). An abnormality occurred in the observations immediately preceding an entry in 42% of cases. Mean ranges of observations over 24 hours were within the limits of normal diurnal variation, although we found that some instances of greater than normal variability were described as “stable.” Conclusions The expression “obs stable” does not reliably indicate normal observations or variations in observations within physiological limits. Doctors should avoid using the expression altogether or clarify it with further information. | 2022-01-27T13:49:35.289Z |
217,693,747 | {
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"DOI": "10.36833/LKL.2017.005",
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} | V Europskych krajinach v posledných rokoch pribuda deti, ktore pred zaskolenim hovoria viac ako len jedným jazykom. Zaroveň vsak casto tieto deti neovladaju jazyk krajiny, v ktorej žiju na dostatocnej urovni. Horsia uroveň znalosti jazyka, v ktorom budu vzdelavane, može veľmi pripominať na prvý pohľad symptomy deti s diagnozou specificky narusený vývin reci alebo naruseneho vývinu reci. Kvoli prekrývaniu znakov v jazykovom obraze viacjazycných deti sa preto stava, že v ramci diagnostiky dochadza k mylnemu nespravnemu diagnostickemu zaveru takýchto deti. Casto su tieto deti oznacene ako deti so specificky naruseným vývinom reci. Aj vzhľadom k tejto aktualnej situacii vznikol jedinecný europsky projekt zastresený europskou výskumnou organizaciou (ESF). Hlavným cieľom v ramci projektu bolo pokusiť sa zjednotiť diagnosticke kriteria v ramci logopedickej a psychologickej diagnostiky bilingvalnych deti so specificky naruseným vývinom reci, a zaroveň sa pokusiť navrhnuť take diagnosticke nastroje, ktore by pomohli senzitivnejsie posudiť jazykovu uroveň bilingvalnych deti. V jednotlivých pracovných skupinach vznikli ulohy na hodnotenie narativ, verbalno-akustickej pamate, slovnej zasoby ako i exekutivnych funkcii. Zaroveň v ramci projektu vznikol navrh dotaznika na posudenie recoveho prostredia bilingvalnych rodin. Zo zaveru projektu jednoznacne vyplýva, že bilingvalne deti so specificky naruseným vývinom reci, budu mať minimalne deficity v obidvoch jazykoch. Rovnako zo zaveru výskumneho projektu vyplýva, že fenomen bilingvalnosti stav deti s naruseným vývinom reci nezhorsuje, neznasobuje ich jazykove deficity v porovnani s monolingvalnymi deťmi s tou istou diagnozou. | 2022-04-01T01:14:59.562Z |
161,838,256 | {
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"DOI": "10.26694/equador.v2i2.1486",
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"status": "BRONZE",
"url": "https://revistas.ufpi.br/index.php/equador/article/download/1486/1160"
} | Os problemas agrários no Piauí, assim como no Brasil, são frutos de realidades construídas ao longo da história, em que o Estado é [ra] considerado o principal responsável pelas realidades encontradas. Tal fato impõe como necessidade para as discussões a respeito da estrutura fundiária do interior piauiense, analisar como o governo tem atuado criando politicas públicas para amenizar os problemas de acesso a terra. Para isso, buscou-se nesse trabalho compreender o processo de surgimento do Assentamento Olho D’agua, situado na cidade de Socorro doPiauí, localizada no sudeste do Estado. Bem como entender como tem se dado a ação dos pequenos produtores sem terra nos territórios onde os movimentos decaráter sócioterritorial como o MST não atuam. Outro fator evidenciado napesquisa refere - se à produção, que em decorrência de resultados nulos emvirtude da seca e da baixa qualidade do solo, ocasiona a existência de assentados trabalhando como arrendatários nas áreas de vazante das terras mais próximas. | 2022-04-22T05:04:47.153Z |
225,183,672 | {
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"DOI": "10.22161/jhed.2.5.5",
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"status": "GOLD",
"url": "https://www.theshillonga.com/index.php/jhed/article/download/125/80"
} | Considering the expansion of Dialectology in Brazil, which, in the 19th century, presented the first clues with the Viscount of Pedra Branca’s publication about the Brazilian Portuguese language compared to the European Portuguese spoken in Portugal, this paper presents the stages of development of the studies carried out since then and lists not only the periods that preceded Brazilian Geolinguistics, but the research that culminated with the publication of States Linguistic Atlases, the publication of the Linguistic Atlas of Brazil in 2014, idealized fifty years before, and the presentation of other documents already completed or designed, thus contemplating the entire Brazil length and completing the fourth phase of Geolinguistic studies. Twelve atlases were published in this phase, whose pioneering role was for Bahia speech, in 1963, and advanced in the work related to Minas Gerais (1977), Paraiba (1977). 1984), Sergipe (1987 and 2002), Parana (1994), The Southern Region (2002), Para (2004), Ceara (2009), Goias (2015), Pernambuco (2016) and Amapa (2017). However, in recent years, researches of linguistic varieties in traditional communities, such as Indigenous, Fishermen and Quilombolas, as are named the descendants and remaining of communities formed by enslaved fugitives, has drawn the attention of researchers and the elaboration of linguistic atlases involving these culturally differentiated people speeches already signals the fifth phase of Geolinguistic studies in the country. Thus, it is intended to present a description of the works, their methodological constitution and a brief overview of the products of these works, which cataloged, at the time of their conclusion, presented specific linguistic marks of the speech of each state and informants’ profiles that allowed the verification of sociocultural interferences. | 2022-06-07T15:22:35.461Z |
140,571,580 | {
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"DOI": "10.9753/ICCE.V33.MANAGEMENT.77",
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} | The ability to predict the imminent arrival of coastal storm risks is a valuable tool for civil protection agencies in order to prepare themselves and, if needs be, execute the appropriate hazard-reduction measures. In this study we present a prototype Early Warning System (EWS) for coastal storm risk on the Emilia-Romagna coastline in Northern Italy. This EWS is run by executing a chain of numerical models (SWAN, ROMS and XBeach) daily, with the final output transformed into a format suitable for decision making by end-users. The storm impact indicator selected for this site is the Safe Corridor Width (SCW), which is a measure of how much dry beach width is available for safe passage by beach users. A three-day time-series of the predicted SCW is generated daily by the prototype EWS. If the minimum SCW exceeds a certain threshold, a warning is issued to end-users via an automated email service. All available prediction information is also updated daily on-line. Over the one year that the EWS has been operating (June 2011 until June 2012), 13 “code red” and 16 “code orange” warnings have been issued, with the remaining 305 predictions indicating low hazard in terms of the SCW. The reliability of the predictions from the perspective of the end-user has meant that the EWS is currently being expanded to include the entire Emilia-Romagna coastline. | 2022-09-09T11:12:47.937Z |
157,734,195 | {
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"DOI": "10.5771/0506-7286-1987-1-110",
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"url": "https://doi.org/10.5771/0506-7286-1987-1-110"
} | Paul Sieghart now brings together for the first time in one volume all the substantive international law of human rights. He first introduces the subject and then considers, one by one, the approximately forty rights, with full cross references. | 2022-12-14T18:07:29.556Z |
54,794,318 | {
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"DOI": "10.2478/acve-2014-0038",
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"status": "GOLD",
"url": "https://content.sciendo.com/downloadpdf/journals/acve/64/4/article-p397.pdf"
} | Abstract Myofibroblasts, cells sharing characteristics with fibroblasts and smooth muscle cells, may have a very heterogeneous origin. The myofibroblasts may be derived from a variety of sources including resident mesenchymal cells, epithelial to mesenchymal transition, as well as from circulating fibroblast-like cells called fibrocytes that are derived from bone-marrow stem cells, or derived from bone marrow precursors. In normal conditions, fibroblastic cells exhibit a low extracellular matrix production ability. After tissue injury, they become activated by cytokines locally released from inflammatory and resident cells to migrate into the damaged tissue and to synthesize extracellular matrix components. The investigation of cytoskeletal and cell surface markers showed a certain degree of heterogeneity of these cells. The reason for this is that markers these cells express to a large extent depend on the type of animal, age and stage of development of fibrosis. A better knowledge of the molecular mechanisms involved in the appearance of differentiated myofibroblasts in different pathological situations will be useful for understanding the development of fibrosis, its prevention and therapy | 2022-12-23T02:19:57.571Z |
13,774,215 | {
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"DOI": "10.1021/JACS.6B06936",
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} | Protein synthesis (translation) is central to cellular function and antibiotic development. Interestingly, the key chemical step of translation, peptide bond formation, is among the slower enzymatic reactions. The reason for this remains controversial because of reliance on studies using highly modified, severely minimized, or unreactive substrate analogues. Here, we investigated this problem by fast kinetics using full-length aminoacyl-tRNA substrates with atomic substitutions that activated the ester electrophile. While trifluoro substitution of hydrogens in nonconserved positions of the peptidyl-site substrate dramatically increased the ester reactivity in solution assays, a large hastening of the combined rates of ribosomal accommodation and peptidyl transfer was observed only with a slowly reacting aminoacyl-site nucleophile, proline. With a fast-reacting A-site nucleophile, phenylalanine, effects did not correlate at all with electrophilicities. As effects were observed using the same, natural, aminoacyl-tRNA at the A site and all rates of accommodation/peptidyl transfer were pH dependent, we concluded that rate limitation was not by A-site accommodation but rather by peptidyl transfer and a hitherto unexpected step at the P site. This new slow step, which we term P-site accommodation, has implications for the activation or inhibition of ribosome function in vitro and in vivo. | 2022-12-26T05:15:48.942Z |
15,356,119 | {
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"DOI": "10.1090/S0002-9939-04-07339-3",
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} | In this paper we prove a cancellation law in the category (1) of partially ordered sets and (2) of To spaces, the respective conditions on the common factor being that it have (1) an irreducible bottom element and (2) an irreducible bottom element in its specialization order. | 2022-12-30T00:29:54.187Z |
163,869,699 | {
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"DOI": "10.7767/OMZ.1989.44.JG.313",
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} | mermusik erklang das Klaviertrio e-moll, op. 102, gespielt von Alfons Kontarsky, Paul Roczek und Heidi Litschauer, sowie die von der tragischen letzten Schaffenskrise überschattete Violinsonate c-moll, op. 139, durch Martin Mumelter und Siegfried Mauser. Ein differenziertes Bild von Max Reger als Orgelkomponist bot das Konzert von Heribert Metzger an der Orgel des Leopold-Mozart-Saales, in dem neben Trios und Choralvorspielen auch die selten gespielte Erstfassung der Fantasie und Fuge d-moll, op. 135 b, erklang. War in diesem Konzert mit der Fantasie und Fuge über B-A-C-H, op. 46, der intensive Bach-Bezug Regers bereits angeklungen, so wurde dieser Aspekt durch die umjubelte Aufführung der Variationen und Fuge über ein Thema von Bach für Klavier, op. 81, durch Alfons Kontarsky bekräftigt, eines Werks, das jedem Solistenkonzert in seinen technischen wie gestalterischen Herausforderungen zur Ehre gereichen würde. Randaspekten des Regerschen Werkes war das letzte Konzert gewidmet: dem Solowerk mit der zweiten Suite für Violoncello solo d-moll, op. 131 c (Johanna Picker), sowie drei Stücken aus „Träume am Kamin" op. 143, in ihrer Brahms-Nähe von Siegfried Mauser am Klavier hervorgehoben. | 2022-01-24T18:26:50.258Z |
125,217,755 | {
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} | Vortex tube is the device that separates pressurized fluid into hot and cold fluid streams simultaneously. The scientific community has done extensive experimental and theoretical studies since invention of vortex tube to augment the performance of the tube by varying geometrical and operational parameters; the paper deals with parametric review of all such work. The review takes into account effect of almost 14 parameters on performance of vortex tube. It includes developments in tube geometry like L/D ratio, number of nozzles; hot end valve angle and cold orifice diameter etc. are discussed along with different fluids and operational parameters like CMF and stagnation point etc. The focus of most of the theoretical and experimental studies was to investigate mechanism of thermal separation and geometry optimization. The main objective of this review is to discuss efforts made in order to enhance the refrigeration effect so that, missing links could help for future research. | 2022-12-07T21:24:14.161Z |
1,206,810 | {
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"DOI": "10.1039/c005387m",
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} | The risk of nanoparticles (NPs) to organisms and the environment has become more noticeable alongside their rapid applications in many fields. The release of Cd(2+) from CdTe-based NPs (CdTe-NPs), an important class of engineered nanomaterials, is one of the possible factors responsible for the cytotoxicity of these NPs. Based on the same CdTe core, CdTe/CdS, CdTe/ZnS and CdTe/SiO(2) NPs were synthesized and their Cd(2+) release rates were carefully studied based on dialysis using inductively coupled plasma mass spectrometry (ICPMS). Results obtained indicated that the Cd(2+) release rates of the CdTe-NPs decreased in the order CdTe (8.78 ng mL(-1) mg(-1) h(-1)) > CdTe/CdS (2.63) > CdTe/SiO(2) (0.89) > CdTe/ZnS (0.72). Phaeodactylum tricornutum was used as a model diatom for evaluating the cytotoxicity of the CdTe-NPs. Results obtained from the CdTe-NPs exposure experiments together with ICPMS and fluorescence microscopy studies suggested that the cytotoxicity of the CdTe-NPs increased along with the increase in their Cd(2+) release rates. Effective coating materials such as ZnS and SiO(2) for the CdTe core significantly reduced the cytotoxicity of CdTe. | 2022-12-17T08:53:48.869Z |
95,143,508 | {
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} | Aquacobalamin (vitamin B12a) formally contains a diamagnetic Co(III) ion encapsulated in the small macrocyclic cavity of the corrin ring. Since the ligand substitution reactions, which proceed through a dissociative interchange mechanism, are fast, the usual inertness of d6 Co(III) has been modified; this points to the ability of the corrin ring to perturb the properties of the metal ion. This phenomenon is explored further in the present work by replacing the H atom at C10 by an electron withdrawing NO group in 10-nitrosoaquacobalamin. This compound, 10-nitrosoaquacobalamin, is characterised by NMR and UV–vis spectroscopy, and by FAB-MS. The pKa of coordinated H2O is determined to be 10.71 ± 0.04 (25 °C, I
= 2.2 mol dm−3, NaClO4), ΔH
= 120 ± 11 kJ mol−1 and ΔS
= 198 ±
38 J K−1 mol−1 (the pKa of B12a itself is 8.09). The strongly electron-withdrawing NO group deactivates the metal ion towards ligand substitution, and neither 1.2 mol dm−3 pyridine nor 0.7 mol dm−3 N3− result in displacement of coordinated H2O; either the reactions are very slow (no observable change in 72 hours) or log K has been decreased by at least 1 and 4 orders of magnitude for coordination of these two ligands, respectively. Hence, the electronic structure of the corrin ring can directly influence the axial ligand binding properties of the metal ion. We demonstrate by studying the temperature-dependence of the kinetics of the substitution of I− in iodocobalamin by imidazole, N3− and S2O32− that, despite the considerable steric barrier of the corrin's
peripheral substituents, the nucleophilic participation of the incoming ligand is retained even when changing H2O to I−, which increases the size of the departing ligand. | 2022-12-18T09:51:22.769Z |
247,720,269 | {
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} | The hepatic diaphragmatic surface is usually smooth and featureless. Although the existing literature mentions grooves or fissures on the diaphragmatic surface, there is no consensus regarding its causative factors. During routine dissection, the authors found a liver with a broad accessory fissure on the anterior surface of the anatomical right lobe. An enlarged hepatic area was observed on the left side of this accessory fissure. The undersurface of the right hemidiaphragm had a diaphragmatic band that extended into the hepatic fissure. The morphometry of the accessory fissure was studied. Retrospective magnetic resonance imaging showed that the middle hepatic vein was to the immediate right of the accessory fissure. Histological examination was done to confirm the presence of muscle tissue in the hypertrophied diaphragmatic band. As the need for surgeries and transplantations of the liver rises, there is a need to understand the hepatic macroscopic anatomy and its radiological correlation. | 2022-12-20T07:41:29.964Z |
11,978,160 | {
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} | Smartphone reminder applications (apps) have the potential to help people with memory impairment after acquired brain injury (ABI) to perform everyday tasks. Issues impacting the uptake of reminder apps for this group are still poorly understood. To address this, three focus groups were held with people with memory impairments after ABI and ABI caregivers (N=12). These involved a discussion about perceptions of, and attitudes towards, reminder apps combined with usability reflections during a user-centred design session (Keep Lose Change) after a walkthrough of an existing reminder app -- Google Calendar. Framework analysis revealed six key themes that impact uptake of reminder apps; Perceived Need, Social Acceptability, Experience/Expectation, Desired Content and Functions, Cognitive Accessibility and Sensory/Motor Accessibility. Analysis of themes revealed issues that should be considered by designers and researchers when developing and testing reminding software for people with memory impairment following ABI. | 2022-12-20T02:13:33.867Z |
188,779,220 | {
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} | با توجه به جایگاه و اهمیت ژئوتوریسم در توسعه مناطق، در پژوهش حاضر20 ژئوسایت از دو شهرستان واقع در شرق استان کردستان (شهرستان های قروه و بیجار) انتخاب شده و مورد ارزیابی قرار گرفته اند. این تحقیق از نوع کاربردی و بر مبنای روش های توصیفی- تحلیلی و نرم افزاری استوار است. ب همنظور ارزیابی ژئوسای ت ها از دو روش کامنسکو و فاسیلاس استفاده شده است. به این ترتیب که پس از ارزیابی با استفاده از معیارها و زیر معیارهای هر کدام از رو شها، بر اساس امتیازات بدس تآمده ژئوسایت های منطقه رتبه بندی شده اند. پس از ارزیابی ژئوسایت ها نقشه پهنه بندی مناطق مستعد توسعه ژئوتوریسم نیز تهیه شده است. برای این منظور از 9 پارامتر (چشم انداز، کاربری اراضی، ارتفاع، شیب، فاصله از راه ارتباطی، فاصله از سایت های فرهنگی، فاصله از رودخانه های فصلی و دائمی، فرسایش و فاصله از ژئوسایت ها) استفاده شده و پهنه بندی از طریق مدل تلفیقی فازی وANPانجام شده است.
نتایج حاصل از ارزیابی ها بیانگر این است که قلعه قمچقای، سراب قروه و چشمه تنگز باباگورگور داری بالاترین ارزش در بین ژئوسایت ها هستند. همچنین بر اساس نتایج بدست آمده از ارزیابی ها و پهنه بندی مناطق مستعد ژئوسایت، ژئوسایت هایی که دارای بالاترین پتانسیل جهت اهداف ژئوتوریستی هستند مشخص شده اند که علاوه بر قلعه قمچقای و سراب قروه، چشمه تنگز و کوه اژدهای باباگورگور، سراب و کوه نسار بیجار، غارگلستانه بیجار و کوه های بدر و پریشان در جنوب شهرستان قروه دارای بیشترین پتانسیل می باشند. | 2022-01-23T03:20:26.955Z |
98,768,025 | {
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} | Acetylesterase (AcE) of Sclerotinia libertiana was purified approximately 1170-fold, and proved homogeneous by electrophoresis, ultracentrifugation and chromatography. The purified AcE hydrolyzed various acetyl esters in the following order; vinyl acetate, tri-acetin, n-butyl acetate, p-nitrophenylacetate, diacetin, ethylene glycol diacetate, monoacetin, ethyl acetate, acetylcholine, methyl acetate. It also had apparently a slight activity on tannic acid, benzoylcholine, methyl butyrate and acetic anhydride.The mode of AcE reaction on these substrates could be divided into two types of group by Lineweaver-Burk plot, one forms the enzyme-substrate complex, ES, and the other, SES additionally combining substrate at a high substrate concentration.From the inhibition experiment by organic acids, it was suggested that the neighbouring carboxyl groups of the di-, or tribasic acid such as citric, cis-aconitic, succinic, and maleic acid have a significance on inhibition of the AcE. Also, choline esterase inhibito... | 2022-08-24T19:37:06.289Z |
213,621,376 | {
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} | Persecution according to the original meaning is a crime against humanity. Violations of human rights. Even some forms of persecution are classified as genocide. In its development, the use of the word perskusi in Indonesia in cases of coercion, ill-treatment, beatings and so on that occurred in the last three years is considered inappropriate and too excessive. Based on the pattern of criminal acts that occur what is referred to as persecution is actually an act of vigilante who in the criminal law system in Indonesia has been known as eigenrechting. Based on the pattern also, the most common criminal element in the act of vigilantism is entering someone else's house without permission, coercion, kidnapping, torture, and beatings. In the fiqh jinayah review, this crime is also classified into several categories of jarimah. The coercive and kidnapping crimes are classified as Jarimah Hirabah. Persecution and beatings belong to jarimah al-jurh. While entering someone else's house, it is Jarimah Ta'zir. | 2022-10-29T17:40:20.945Z |
31,844,386 | {
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} | 1 By using a specific sensitive stable-isotope dilution gas chromatography-mass spectrometry (GC-MS) assay, hydrazine was detected in the plasma of eight healthy male volunteer subjects taking isoniazid (300 mg daily) for 2 weeks. 2 Accumulation of hydrazine occurred in slow-acetylator phenotypes. 3 Hydrazine was also detected in the plasma of eight out of 14 hypertensive patients treated chronically with hydralazine (200 mg daily). 4 However, the concentrations of hydrazine observed were much lower than in the isoniazid study and were close to the limit of detection. 5 As hydrazine is hepatotoxic, mutagenic and carcinogenic in animals, its presence in human plasma has important toxicological implications. | 2022-12-23T21:31:19.406Z |
131,343,456 | {
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} | The uplift and denudation of the Colorado Plateau is important in reconstructing the geomorphic and tectonic evolution of western North America. A Late Cretaceous (64 ± 2 Ma) U‐Pb age for the Long Point limestone on the Coconino Plateau, which overlies a regional erosional surface developed on Permo‐Triassic formations, supports unroofing of the Coconino Plateau part of Grand Canyon by that time. U‐Pb analyses of three separate outcrops of this limestone gave ages of 64.0 ± 0.7, 60.5 ± 4.6, and 66.3 ± 3.9 Ma, which dates are older than a fossil‐based, early Eocene age. Samples of the Long Point limestone were dated using the isotope dilution isochron method on well‐preserved carbonates having high‐uranium and low‐lead concentrations. Our U‐Pb ages on the Long Point limestone place important constraints on the (1) time of tectonic uplift of the southwestern Colorado Plateau and Kaibab arch, (2) time of denudation of the Coconino Plateau, and (3) Late Cretaceous models of paleocanyon incision west of, or across, the Kaibab arch. We propose that the age of the Long Point limestone, interbedded within the Music Mountain Formation in the Long Point area, represents a period of regional aggradation and a time of drainage blockage northward and eastward across the Kaibab arch, with possible diversion of northward drainage on the Coconino Plateau westward around the arch via a Laramide paleo‐Grand Canyon. | 2022-12-30T00:35:28.825Z |
210,311,716 | {
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"DOI": "10.32628/CSEIT184514",
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} | This paper presents the various wind turbine technologies for energy management in buildings. Zero energy buildings are the buildings in which the total energy consumed by the whole building will be equal to the total energy that is produced or generated by those buildings using renewable sources of energy. The structure of building includes the wind turbines in its structure only so that the wind that is passing in the environment of the building can be used for energy generation purpose also for the building. This paper is emphasis on the zero energy buildings for development of the nation. Further, Building augmented wind turbines installed between two buildings are also discussed briefly in the manuscript. | 2022-02-08T03:32:20.168Z |
136,681,376 | {
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} | [82942-26-5]P
(N-benzylmethylaminopyridine polymer bound; N-methyl-N-(4-pyridyl)aminomethyl-polystyrene cross-linked with divinylbenzene; reagent used as recyclable catalyst for acylation reactions)
Form Supplied in: 2–4% cross-linked poly(styrene-co-divinylbenzene) as resin type; commercially available.
Analysis of Reagent Purity: typical loading 2.5–3.0 mmol N g−1 (dry).
Preparative Methods: several syntheses for typical polymeric forms of (dimethylamino)pyridine have been published: (i) Condensation reaction of laurylated poly(ethyleneimine) with 3-[N-methyl-N-(4-pyridyl)amino]propionic acid.1 (ii) Substitution reaction of polystyrene bearing (methylamino)methyl substituents with 4-chloropyridine.2 (iii) Copolymerization of 4-(N-methyl-N-para-vinylbenzylamino)pyridine, styrene and commercially available divinylbenzene (DVB).3 (iv) Chemical modification of halogenated bead polymers such as chloromethylstyrene copolymer with 4-(N-methylamino)pyridine.4 | 2022-02-09T10:59:45.281Z |
91,083,876 | {
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} | ABSTRACT The objectives of this research were carried out to determine exposure time of giant gouramy larvae in triiodothyronine (T 3 ) hormone solution on development, growth and survival rate. One-day old larvae were immersed in 0,1 ppm T 3 hormone solution for 0, 2, 4, 6, 8, 16, and 24 hours. Results showed that treated larvae developed faster than control larvae. At first, second, fifth, sixth and seventh week, larvae that immersed in T 3 hormon solution had total length longer than that of control. Treated larvae had average body weight heavier than that of control until seven weeks of experiment. Immersion of larvae for 16 hours gave the best result in term of length and average body weight. The best survival rate of larvae were obtained from 8 hours treatment. Key words : Giant gouramy larvae, triiodothyronine, exposure time, growth and survival rate. ABSTRAK Penelitian ini dilakukan untuk menentukan lama perendaman di dalam larutan hormon triiodotironin (T 3 ) terhadap perkembangan, pertumbuhan dan kelangsungan hidup larva ikan gurame. Larva ikan yang berumur satu hari direndam dalam larutan hormon triiodotironin 0,1 ppm dengan lama perendaman 0, 2, 4, 6, 8, 16, dan 24 jam. Perkembangan larva yang diberi perlakuan T 3 lebih cepat daripada perkembangan larva kontrol. Larva yang direndam dalam larutan hormon T 3 lebih panjang daripada kontrol pada minggu ke-5, 6 dan 7. Bobot rata-rata larva perlakuan lebih besar daripada bobot rata-rata kontrol dari minggu awal sampai minggu ke-7. Perendaman larva selama 16 jam memberikan hasil terbaik dari segi panjang total dan bobot rata-rata. Nilai kelangsungan hidup terbaik di akhir penelitian diperoleh pada perendaman selama 8 jam. Kata kunci : Larva gurame, triiodotironin, lama perendaman, pertumbuhan dan kelangsungan hidup. | 2022-02-10T18:30:48.033Z |
252,361,381 | {
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} | This study aims to explain the results of the test implementation of the Android-based Multi-History application as historical teaching material. Therefore, innovation is needed in history learning, one of which is through digital teaching materials. This research uses descriptive qualitative research methods. The background of this research is that digitalization in the field of education allows all activities to be carried out remotely (online), one of which is history learning. Educators find it difficult when required to use teaching materials/media that are all digital. The sophistication of technology has also resulted in a fast-paced exchange of information. As a result, many hoax news is unstoppable and smell of hate speech which results in the degradation of the tolerance attitude of the next generation. The product developed has gone through material validation, media validation, and product trials until it is considered worthy of being said to be teaching material and can be used as a solution from the use of teaching materials / digital media and as an effort to increase the tolerance attitude of students. The results showed that: (1) the Multi-History application is easy and practical in its use, (2) Suitable for use in any learning method because the material in the application is presented in the form of text, audio, and even audio-visual, (3) cheap and free students only need to install from the device for its operation, (4) the material is easy to understand and interesting because it is presented in digital form. | 2022-09-23T00:22:08.370Z |
119,688,882 | {
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"DOI": "10.1088/1464-4258/6/5/004",
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} | With an example of the Laguerre–Gaussian LG01 mode we show that the free-space evolution of a vortex light beam can be interpreted as the mechanical motion of a 'body' whose density is determined by the mass equivalent of the beam energy. As mechanical attributes, this 'body' possesses angular velocity and moment of inertia, in addition to the common orbital angular momentum. The beam 'body' is not rigid and its radial layers glide with respect to each other analogous to the motion occurring in fluid vortices. Absolute values of the layer velocities agree with the energy transfer rates following from the consideration of the Poynting vector distribution. | 2022-09-23T11:12:45.597Z |
71,700,209 | {
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"DOI": "10.5336/MEDSCI.2008-8613",
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} | ABS TRACT Objective: To in ves ti ga te whet her the cer vi cal mu cus in preg nants has an ti mic ro bi al activity in vit ro and to de ter mi ne its re la ti ons hip with prog no sis of preg nancy. Material and Met hods: Cervi cal mu cus samp les we re col lec ted from 50 wo men with sing le preg nancy du ring the first tri mes ter. Ste ri li zed Wart man pa pers we re so a ked in to mu cus samp les and dri ed un der ste ri le con di ti ons. Cul tu ring was per for med by disk dif fu si on met hod which uses Mil ler Hin ton me di um and Mac-Far land 0.5 so lu ti on pre pa red with Staph ylo coc cus au re us, Esc he ric hi a co li, Kleb si el la pne u mo ni a and Can di da albi cans. Po si ti ve or ne ga ti ve zo nes we re de ter mi ned by me a su ring the di a me ters of in hi bi ti on zo nes occur red fol lo wing 18 ho urs in cu ba ti on pe ri od. Prog no sis of preg nants with or wit ho ut an ti mic ro bi al ef fect of cer vi cal mu cus we re com pa red. Re sults: In 28 ca ses, it was de mons tra ted that cer vi cal mu cus had an ti mic ro bi al ef fects. Du ring the fol low-up pe ri od of 27 preg nants, 22 (81.5%) ga ve vi ab le birth in term, 3 (11.1%) had abor tus, and 1 (3.7%) had early mem bra ne rup tu re at 36th we ek of ges ta ti on. In 22 ca ses, cer vi cal mu cus sho wed no an ti mic ro bi al ef fect. 20 of the se fol lo wed-up and 14 (70.0%) parti ci pants ga ve vi ab le birth at term, 3 (15.0%) had abor tus, and 2 (10.0%) had pre term de li very. The re was no sta tis ti cally sig ni fi cant dif fe ren ce bet we en the two gro ups in terms of preg nancy prog no sis. Conclusion: Cer vi cal mu cus pre vents in fec ti ons from va gi na to up per ge ni tal or gans not only mec ha ni cally but al so by func ti o ning as a che mi cal bar ri er. In our study, it is es tab lis hed that presence or absence an ti mic ro bi al ef fect of mu cus do es not ha ve a sig ni fi cant im pact on the prog no sis of preg nancy. We think that stu di es with gre a ter num ber of par ti ci pants may gi ve dif fe rent re sults. | 2022-10-14T00:30:56.686Z |
85,747,420 | {
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"DOI": "10.5897/IJPPB2012.027",
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} | Information on different rangeland plants’ nutritive values at various growth stages is important in rangelands management. This information helps rangeland managers to choose proper grazing times to achieve higher animal performance without detrimental effects on the rangeland vegetations. Effects of various plant parts’ growth stages and vegetation types on reserve carbohydrates and forage quality indicators were investigated during 2009 and 2010. Plant samples were collected from natural rangelands in Iran with completely randomized block (CRB) design. The species included, two grass species (Secale montanum and Festuco ovina), two forbs (Lotus corniculatus and Sanguisorba minor) and two shrubs (Kochia prosterata and Salsolarigida). Aerial plant parts’ samples were oven-dried at 80°C for 24 h, then analyzed for soluble carbohydrates, crude protein (CP), acid detergent fiber (ADF), dry matter digestible (DMD) and metabolizable energy (ME). Results showed that plants at the seedling stage had more reserve carbohydrates and from the three vegetation types (grass, forbs, and shrub), forbs contained more soluble carbohydrates as compared to the other two (grasses and shrubs). Differences in soluble carbohydrate contents of different species at various growth stages in 2 years were statistically significant. The forage quality indicators (CP, ADF, DMD and ME) in different species, in various vegetation types, in the 2 years were statistically significant, except for the CP.
Key words: Phonological stage, forage quality, protein, fiber. | 2022-12-11T12:15:37.921Z |
35,307,576 | {
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"DOI": "10.1109/EPTC.2008.4763589",
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} | It is a well known fact that vibration is one of the most important loading condition in electronic systems. This study deals with dynamic analysis of a printed circuit board (PCB) with a component on it under vibratory loading. The objective of the study is to develop an analytical model for common PCB configurations and electronic components on them in order to predict dynamics of the assembly under vibratory loading, and thus to study the effects of component location. As an application, in this paper an analytical model of a simply supported PCB with a component is presented. The validity of the two degree of freedom analytical model is demonstrated by comparing numerical results for random vibration input with those of a finite element model. | 2022-09-15T08:17:35.718Z |
28,713,071 | {
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"DOI": "10.1111/j.1523-1739.2010.01640.x",
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"license": null,
"status": "CLOSED",
"url": null
} | Losses of biological diversity, or diversity of life at all
levels of biological organization, have crossed a boundary
beyond which they pose serious consequences for humanity (Rockstrom et al. 2009). Despite enormous effort by state and global actors to arrest declines in biological diversity, rates of deforestation in the tropics
remain high (Asner et al. 2009). Centralized state control
of forests and other ecosystems, in the form of national
parks and other protected areas, has been a dominant
conservation paradigm, and it has been fueled by neoliberal
approaches in international conservation (Brockington
et al. 2008). The protected-area approach has often resulted in adverse effects on the livelihoods of local people (Saberwal et al. 2001; Adams & Hutton 2007). Due
to the high spatial correlation between poverty and high
levels of biological diversity (Sachs et al. 2009), attempts have been made to link conservation of biological diversity with livelihoods and poverty alleviation (Adams et al.2004). Such efforts have had limited success due to a
lack of understanding of the linkages between poverty
and conservation and the absence of state support for
alternative approaches (Agrawal & Redford 2006; Lele
et al. 2010). Conservation projects in which increasing
income is assumed to decrease dependence on resources
(Brechin et al. 2002) treat poverty too simply (Sen 1999).
We propose that the process of conservation be reenvisioned
to include political empowerment to people,restitution of rights and human dignity, and building of local institutions. A human-rights-based approach increases
the role of local communities in conservation and the potential for democratic governance of natural resources. Using India as an example, we offer suggestions for developing decentralized mechanisms to restorerights to local communities. Our suggestions are applicable
to much of the developing world, where poverty
and centralized management of protected areas have not
curtailed losses of biological diversity and have alienated
local communities (Sodhi et al. 2006). We do not
assume that rights-based approaches will mitigate loss
of biological diversity, but suggest that efforts based
on local knowledge, institutions, and practices will empower local communities to better manage biological
diversity. | 2022-12-08T17:26:30.659Z |
143,811,612 | {
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"DOI": "10.1163/156920612X634492",
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} | Abstract In The Necessity of Art Ernst Fischer develops a Marxist aesthetics in the humanist tradition, arguing art’s necessity as both a vehicle of social criticism and as an essential element of humanity. These twin themes place Fischer’s work, then, at the centre of issues in Marxist aesthetics that have traditionally proved contentious: firstly, about the function of art, both under capitalism and universally; and about the relationship – causal or otherwise – between economic conditions and art. Fischer’s aesthetics overemphasises the humanising possibilities of great works of art to the neglect of an everyday aesthetics that argues the possibilities for aesthetic lives based on good work under communism. But he provides a theoretic start to effectively countering structuralist Marxism, and he was in his lifetime – as John Berger’s Introduction movingly conveys – a powerful opponent of the bureaucratisation of art under Zhdanov’s Socialist-Realist creed. | 2022-12-11T03:55:40.791Z |
255,144,434 | {
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"DOI": "10.32653/ch184975-992",
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"license": "CCBY",
"status": "GOLD",
"url": "https://caucasushistory.ru/2618-6772/article/download/975-992/1696"
} | The article deals with the study of Islamic consciousness in terms of the institution of zakat in its historical development and the prospects for its development in the modern historical process. Islamic spiritual leaders set the goal of implementing the ideas of the Islamic economy in countries and regions with a Muslim population and demonstrating the benefits of the Islamic economic model. This idea manifested itself rather strongly in the Volga region, in the North Caucasus, including Dagestan. There are ongoing processes of formation of Islamic economic thinking. The significance of the institute of zakat in the implementation of the Islamic economic model determines the relevancy of the study. This model claims to be competitive with the liberal model that dominates the modern world. The article shows the main provisions of the institute of zakat, determined by the fundamental Islamic sacred texts. The controversial issues of a legal nature are discussed, caused by external factors of a social nature. At the same time, we note that external factors are essential in changing the socially significant functions of zakat. The author concludes that the introduction of legal innovations in the institution of zakat did not affect its essential characteristics, defined by sacred texts. In determining the importance of zakat in the religious life of a modern Dagestan Muslim, the results of a sociological survey conducted by the author in 2021 have been used. The survey shows, firstly, that an ordinary Muslim does not have the necessary knowledge regarding zakat. In particular, under which circumstances and which property tax he is obliged to pay, designated as one of the pillars of Islam. Secondly, this tax is paid by an insignificant part of those who call themselves Muslims. The results of the survey lead to the conclusion that the institution of zakat, as the most important component of Islamic economic activity, is not sufficiently covered in the life of ordinary Muslims of Dagestan. | 2022-12-30T00:33:32.170Z |
199,589,535 | {
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"DOI": "10.1162/isal_a_00223",
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"license": "CCBY",
"status": "GREEN",
"url": "https://arts.units.it/bitstream/11368/2947152/6/cover%2bindex.pdf"
} | Soft robots allow for interesting morphological and behavioral designs because they exhibit more degrees of freedom than robots composed of rigid parts. In particular, voxel-based soft robots (VSRs)—aggregations of elastic cubic building blocks—have attracted the interest of Robotics and Artificial Life researchers. VSRs can be controlled by changing the volume of individual blocks: simple, yet effective controllers that do not exploit the feedback of the environment, have been automatically designed by means of Evolutionary Algorithms (EAs). In this work we explore the possibility of evolving sensing controllers in the form of artificial neural networks: we hence allow the robot to sense the environment in which it moves. Although the search space for a sensing controller is larger than its non-sensing counterpart, we show that effective sensing controllers can be evolved which realize interesting locomotion behaviors. We also experimentally investigate the impact of the VSR morphology on the effectiveness of the search and verify that the sensing controllers are indeed able to exploit their sensing ability for better solving the locomotion task. | 2022-09-15T07:26:59.311Z |
211,033,964 | {
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"DOI": "10.2147/OTT.S231125",
"MAG": "2997510327",
"PubMedCentral": "6942534"
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} | Background Osteosarcoma (OS) is one of the most difficult cancers to treat due to its resistance to chemotherapy. The essential role played by Mcl-1 in promoting chemoresistance has been observed in a variety of cancers, including OS, while the underlying mechanism remains unclear. Methods We investigated the expression of Mcl-1 in 42 paired OS specimens obtained before and after adjuvant chemotherapy, and its correlation with clinicopathological characteristics. Loss and gain of function studies were performed to analyze the effects of Mcl-1 modulations on the chemosensitivity, and the mechanism involved in the deregulation of Mcl-1 in OS cells. Results In OS specimens, the expression of Mcl-1 was significantly upregulated after chemotherapy, and high Mcl-1 expression was associated with poorer overall survival and an increased recurrence rate. Furthermore, we demonstrated that chemotherapy-driven increased Mcl-1 decreased chemosensitivity by promoting tumour proliferation and inhibiting DNA damage. Moreover, Mcl-1 was found to be a direct target of miR-375 in OS cells. The knockdown of Mcl-1 phenocopied miR-375 downregulation, and the overexpression of miR-375 rescued the effects of cisplatin-induced DNA damage mediated by Mcl-1. Conclusion Our data indicated that chemotherapy-driven increase in the expression of Mcl-1 plays a critical role in chemoresistance, and the intervention of the miR-375/Mcl-1 axis may offer a novel strategy to enhance chemosensitivity in OS treatment. | 2022-10-01T07:10:40.727Z |
247,369,017 | {
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"DOI": "10.1080/23802359.2022.2050472",
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"PubMedCentral": "8920384"
},
"license": "CCBY",
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"url": "https://www.tandfonline.com/doi/pdf/10.1080/23802359.2022.2050472?needAccess=true"
} | Abstract Indigofera stachyodes Lindl. is a traditional medicinal plant in southwestern China. In this study, we report the complete chloroplast genome sequence of I. stachyodes, using next-generation sequencing technology. The complete chloroplast genome of I. stachyodes was 158,039 bp in length with an overall GC content 35.80%, containing a large single-copy (LSC) region of 88,772 bp, a small single-copy (SSC) region of 18,733 bp, and a pair of inverted repeats (IRs) regions of 25,267 bp. In total, there are 128 genes (83 protein-coding genes (PCGs), eight ribosomal RNA (rRNA) genes, and 37 tRNA genes) in the whole chloroplast genome, including 113 unique genes (78 unique PCGs, 31 unique tRNAs, and four unique rRNAs). The phylogenetic analysis indicated that I. stachyodes formed a monophyletic clade with I. tinctoria and I. linifolia, showing that they have close relationship. The complete chloroplast genome of I. stachyodes provides valuable genomic information for the phylogeny, molecular identification and sustainable utilization of this species. | 2022-04-09T13:13:24.978Z |
108,844,659 | {
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} | The second part of this paper deals with the analysis of the 2D LDA measurements carried out within the high-speed multistage axial compressor CREATE. First the interactions correlations are quantified using the deterministic stresses introduced by Adamczyk. Secondly, a modal decomposition shows that the interactions are characterized by the presence of spatial harmonics (spinning lobes) given by a linear combination of the blades numbers. An original measurement of the rotating speed of the spinning lobes has been carried out allowing to identify almost all the spinning lobes in the first inter row region resulting from the R1-S1 interactions. For the first stage, where the influence of the downstream rows is low, the measured flow field is well reproduced by the model of Tyler and Sofrin. Spatial DFT of the flow field calculated for each time of the compressor time period show that there is a pulsation of the spatial harmonics with the period associated to the minimum elapsed time to recover the same relative positions of the rotor and stator rows.© 2004 ASME | 2022-12-05T00:43:19.049Z |
28,342,305 | {
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} | The angiotensin type 1 receptor (AT1R) is a seven transmembrane spanning G proteinYcoupled receptor mediating the actions of its endogenous ligand, angiotensin II, including arterial blood pressure control and salt-water balance. Overactivity of this angiotensin II-AT1R interaction results in hypertension and disorders of vascular remodeling. Activating anti-AT1R antibodies (AT1RAA) are nonYhuman leukocyte antigen subclasses IgG1 and IgG3 antibodies directly involved in the pathophysiology of autoimmune vascular diseases of pregnancy, preeclampsia, systemic sclerosis, and malignant hypertension (1). The AT1RAA also contribute to refractory vascular rejection after renal allograft transplantation (2) and rejection occurring 5 years after heart transplantation (1). Can the presence of AT1RAA also predict chronic graft-versus-host disease (cGvHD) after hematopoietic stem cell transplantation (HSCT)? In this issue of Transplantation, Chiron et al. (3) measured AT1RAA and their association with clinical symptoms and biological markers in a retrospective study of 45 HSCT patients with extensive cGvHD and 42 HSCT age-matched and sex-matched patients without cGvHD. The frequency of AT1RAA measured 39 months after HSCTwas significantly increased (odds ratio [OR], 3.4) in the cGvHD group (24.4%) compared with the non-cGvHD group (7.1%). This preliminary study therefore does raise a potential role and prognostic value of AT1RAA measurements in cGvHD, whereby these antibodies might act as agonists with AT1R to induce endothelial activation and increased proinflammatory and fibrotic responses in target organs (Fig. 1). However, in the cGvHD group, the positivity of AT1RAA was also associated with more likelihood of antinuclear antibodies (OR, 5.9), which might also indicate underlying increased autoimmunity. Nevertheless, a more severe global and organ-specific cGvHD scoring was present, and active skin or mucosal erosions were far more common and occurred sooner in the presence of AT1RAA (OR, 19.2). There was no difference between the number and the types of organs involved by the cGVHD in AT1RAAYpositive or AT1RAAYnegative individuals. Interestingly, despite the important role of angiotensin II in the control of blood pressure and kidney function, there were no differences in blood pressure or kidney function between groups. The AT1RAA were also present in 5% of healthy normal individuals, indicating a possible lack of specificity. However, it is likely that AT1RAA are produced by donor plasma cells, as immune reconstitution occurs from the donor origin after HSCT. In this regard, in seven patients with cGvHD and AT1RAA, only one tested positive for AT1RAA in the pretransplant period in the current study by Chiron et al. (3) This indicates that positivity of AT1RAA is likely to be associated with the de novo development of antibodies from donor plasma cells and the subsequent development of cGvHD. What is the emerging evidence for a broader role for AT1RAA in human disease? The AT1RAA activate AT1R in a similar way as angiotensin II, with activation of extracellular signal-regulated kinases (ERK) 1/2 kinase and increased expression of the transcription factors, activator protein-1 (AP-1) and nuclear factor-KQ and downstream | 2022-02-12T14:25:21.245Z |
132,954,228 | {
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"DOI": "10.29313/ethos.v0i0.1795",
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},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://ejournal.unisba.ac.id/index.php/ethos/article/download/1795/pdf"
} | Jumlah publikasi dari Indonesia sangat sedikit dibanding dengan negara tetangga seperti Malaysia dan Singapura. Padahal jumlah tenaga pendidik Indonesia sangat banyak dibanding dengan Negara tetangga. Hal ini disebabkan oleh beberapa faktor yang membuat minat menulis dari pendidik sangat rendah, diantaranya adalah ketidaktahuan dalam penggunaan perangkat lunak. Oleh karena itu kami tertarik untuk melakukan penelitian untuk mengkaji pengaruh penguasaaan perangkat lunak terhadap minat menulis dari tenaga pendidik. Dalam penelitian ini kami meneliti para pendidik Sekolah Dasar di daerah Cipayung Jakarta Timur. Penelitian ini menggunakan metode kuesioner kepada tenaga pendidik di daerah Cipayung Jakarta Timur. Hasil penelitian menunjukkan bahwa pengenalan dan pelatihan perangkat lunak kepada para tenaga pendidik dapat meningkatkan minat untuk penulisan karya ilmiah. Disamping itu perlu diadakan penyuluhan secara rutin dan berkesinambungan dalam hal publikasi bagi guru-guru SD sampai SMA untuk meningkatkan minat penulisan karya ilmiah. | 2022-06-03T08:32:21.063Z |
8,341,513 | {
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} | Our experts consider a hot topic of the day. | 2022-06-30T20:06:34.202Z |
249,622,102 | {
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"DOI": "10.1091/mbc.P22-03-1007",
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} | Relatively few studies have addressed how aging contributes to late-onset Alzheimer's disease (LOAD) development and the mechanisms remain largely unknown. Here the authors integrate gene expression data from ∼1000 brains, comparing normal aging with LOAD individuals across different brain regions and identify normal aging-specific and LOAD-specific gene expression signatures. They also identify a subgroup of normal-aging samples highly similar to LOAD, representing individuals with high risk for developing LOAD. This high-risk gene expression signature contains excellent candidates for future studies on the early molecular mechanisms of LOAD development. The systems biology approach used can and should be more widely applied to study other diseases using previously available databases. | 2022-08-24T16:10:46.102Z |
121,769,619 | {
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"DOI": "10.1063/1.3621806",
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} | As well as being amongst the most powerful objects in the Universe, Gamma Ray Bursts (GRBs) are plausible sources of the highest energy cosmic rays. Therefore GRBs are expected to be sources of high energy neutrinos. So far all searches have turned negative results, and the default models are being challenged. With the recent completion of the IceCube neutrino telescope, the question of whether GRBs are the sources of the highest energy cosmic rays will be thoroughly tested. A successful detection would enable new exciting methods to conduct astrophysical studies and complement electromagnetic observations. In this proceeedings, the prospects for positive detection with neutrino observatories will be surveyed with an emphasis on IceCube.The connection between long duration GRBs and core collapse supernovae, has led to the hypothesis that there is be a population, possibly a couple of orders of magnitudes larger than the GRB population, of so called choked GRBs. These choked GRBs are also predicted to be s... | 2022-09-04T10:39:12.722Z |
208,865,760 | {
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"DOI": "10.1103/PHYSREVLETT.95.061801",
"MAG": "2962783897",
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},
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} | We present a measurement of CP-violation parameters in the B0 -> KsKsKs decay based on a sample of 275 x 10^6 BBbar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB energy-asymmetric e+e- collider. One neutral B meson is fully reconstructed in the decay B0 -> KsKsKs, and the flavor of the accompanying B meson is identified from its decay products. CP-violation parameters are obtained from the asymmetry in the distributions of the proper-time interval between the two B decays: S = +1.26 +/- 0.68(stat) +/- 0.20(syst) and A = +0.54 +/- 0.34(stat) +/- 0.09(syst).
We present a measurement of CP-violation parameters in the B0 -> KsKsKs decay based on a sample of 275 x 10^6 BBbar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB energy-asymmetric e+e- collider. One neutral B meson is fully reconstructed in the decay B0 -> KsKsKs, and the flavor of the accompanying B meson is identified from its decay products. CP-violation parameters are obtained from the asymmetry in the distributions of the proper-time interval between the two B decays: S = +1.26 +/- 0.68(stat) +/- 0.20(syst) and A = +0.54 +/- 0.34(stat) +/- 0.09(syst). | 2022-09-24T21:22:08.974Z |
171,448,025 | {
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"DOI": "10.3986/sms.v1i0.1868",
"MAG": "2751673603",
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},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://ojs.zrc-sazu.si/sms/article/download/1868/1615"
} | The author describes a complex of specific characteristics of South Slavic demonology which also appears in other Balkan notions about demons. | 2022-12-02T12:08:34.787Z |
253,461,464 | {
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"DOI": "10.1109/ISCAS48785.2022.9937417",
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} | This paper investigates direct and indirect learning methods to develop deep learning digital predistortion (DL-DPD) models and apply the models to improve the linearity of a power amplifier (PA). The two methods are applied to class-AB and class-$\mathrm{F}^{-1}$ PAs designed with gallium nitride (GaN) on silicon carbide (SiC) high electron mobility transistors (HEMTs). The simulation results show that both direct and indirect DL-DPD methods improve the linearity of the class-AB PA by about 12dB and the class-$\mathrm{F}^{-1}$ PA by 11 dB, while the indirect method offers marginally better performance. The paper shows the direct learning method leads to significant improvement of the DL-DPD method based over the memory polynomial. It also presents the advantages of a BiLSTM based on the neural network architecture to design direct/indirect DPDs. Finally, it demonstrates that the DL-DPD can improve the linearity of class-AB and class-$F^{-1}$ PAs without architectural changes. | 2022-11-18T14:34:05.184Z |
16,392,338 | {
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"DOI": "10.2174/1874440001206010103",
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"PubMedCentral": "3499734"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "http://benthamopen.com/contents/pdf/TONIJ/TONIJ-6-103.pdf"
} | Although human brain development continues throughout childhood and adolescence, it is a non-linear process both structurally and functionally. Here we review studies of brain development in healthy children from the viewpoint of structure and the perfusion of gray and white matter. Gray matter volume increases and then decreases with age, with the developmental time of the peak volume differing among brain regions in the first and second decades of life. On the other hand, white matter volume increase is mostly linear during those periods. As regards fractional anisotropy, most regions show an exponential trajectory with aging. In addition, cerebral blood flow and gray matter volume are proportional at similar developmental ages. Moreover, we show that several lifestyle choices, such as sleeping habits and breakfast staple, affect gray matter volume in healthy children. There are a number of uninvestigated important issues that require future study. | 2022-12-15T12:55:10.382Z |
121,959,830 | {
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"DOI": "10.1117/12.846037",
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} | We have tested an aluminum-coated Iris AO Micro-Electrical Mechanical System (MEMS) segmented Deformable Mirror (DM) for its behavior in the presence of high energy 532 nm laser light. The DM was subject to several tests in which the laser power and the duration of its incidence was varied. The DM experienced an irradiance of 94.5 W cm-2 at the maximum laser power of 2 W. A slight permanent reduction in the amount of bow in each segment was observed. This is most likely due to annealing. The mirror remained fully functional during and after the tests. Measurements of the mirror's temporal stability and position repeatability were performed before the laser test. We found a 1.28 nm rms variation in the bow of segments that is highly correlated over the 16 minute test. The mirror's ability to return to its initial position was within the 1.34 nm rms instrument noise. These results are encouraging for applications such as the laser uplink correction of the Visible Light Laser Guidestar Experiment (Villages) and future multi-Laser Guidestar systems (LGS). | 2022-12-19T09:57:28.401Z |
120,414,415 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.2514/6.1976-843",
"MAG": "1999202330",
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} | A class of highly inclined lunar orbits is discussed for which earth perturbations have significant influence on the orbit evolution and the usefulness of the orbit for scientific exploration. The theory of the long-term motion of particles under third-body and zonal harmonic perturbations is taken as a starting point for investigations of orbits with relatively long lifetimes and evolutionary patterns that enhance the effectiveness of the satellite as a lunar farside relay. An equilibrium solution in the doubly-averaged three-body problem with oblateness is identified and the results of some numerical integrations are presented. | 2022-12-25T21:34:59.029Z |
191,619,200 | {
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"DOI": "10.5553/Bw/016571942017071003004",
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} | textabstractDe term ‘tweedeordeverkiezing’ geeft aan dat sommige verkiezingen van minder
groot belang zijn voor burgers dan nationale verkiezingen. Dit artikel gaat na in
hoeverre dat geldt voor de Nederlandse gemeenteraadsverkiezingen. Het bouwt
voort op de literatuur over het tweedeordekarakter van lokale verkiezingen in
Nederland. De auteurs richten zich op de vraag in hoeverre Nederlandse gemeenteraadsverkiezingen
tweedeordeverkiezingen zijn door het stemmen bij de lokale en
nationale verkiezingen op verschillende manieren met elkaar te vergelijken. Ze vergelijken
vier aspecten van lokaal en nationaal stemmen: de opkomst, de achterliggende
factoren die opkomst verklaren, de factoren die een stem voor lokale partijen
verklaren, en het nationale of lokale karakter van stemmotieven bij de gemeenteraadsverkiezingen
in 2014. De resultaten geven geen eenduidig antwoord op de
vraag in hoeverre gemeenteraadsverkiezingen lokaal georienteerd zijn. De vier verschillende
invalshoeken leveren allemaal dubbelzinnige patronen op. Gemeenteraadsverkiezingen
hebben dus inderdaad deels een tweedeordekarakter, zoals eerder
betoogd en getoond. Toch mogen we de lokale affiniteit en politieke betrokkenheid
ook niet onderschatten. Dat een deel van de burgers zich wel interesseert in de
lokale politiek, in lokale partijen en in verkiezingsprogramma’s van lokale afdelingen
wijst wel degelijk op een lokale politieke dynamiek. | 2022-12-30T00:55:58.688Z |
141,222,600 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1002/HRDQ.3920090403",
"MAG": "2130435519",
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},
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"url": null
} | Results of this study help identify those who serve both vocational and psychosocial mentoring functions. Mentoring research has suggested that proteges are drawn to competent mentors (Olian, Carroll, Giannantonio, and Feren, 1988) but has not empirically examined which mentors serve both vocational (career-related) and psychosocial (personal development) functions. Serving in both capacities indicates the most intense mentoring (Kram, 1983). In this study, older mentors who have greater organization-based self-esteem (OBSE), who perceive the protege as competent, and who are influenced by their proteges reported serving more vocational and psychosocial mentoring functions. Proteges indicated that the matter of who initiates the relationship determines whether vocational and psychosocial functions are both served. | 2023-01-01T19:08:23.674Z |
46,961,635 | {
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"DOI": "10.1109/ICASE.2017.8374274",
"MAG": "2805857821",
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},
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} | Medical geography helps to quickly expose data base development, analyzing, modeling, mapping and visualization of data. Present study was aimed to provide data to public health authorities for allocation of resources and prevention of disease in high risk areas. Data related to diseased people was requested from District Health Office Rawalpindi for all the tehsils of Rawalpindi district on monthly basis from 2011–2015. Topographic map of the study area was purchased from Geological Survey of Pakistan where as health facilities locations were recorded using Trimble Nomad 900 receiver and also cross checked by importing it on Google EarthTM for accuracy assessment. Different geo-statistical tools were applied to check the pattern of disease using ArcGIS. Negative values of Moran' I statistic showed random distribution pattern in District Rawalpindi where as Anselin local Moran's I statistic identify the spatial outliers in data for Viral Hepatitis which were Rhc-Kotli Sattian and Bagga Shaikhan from 2011–2015 in Rawalpindi district. Getis-Ord Gi∗ statistic showed hot spots in Rawalpindi, Kotli Sattian and Muree tehsils. Centrographic statistics showed that spread of the disease is from South-West to North-East. This study proposed that there is a serious need to analyze the spatial outlier areas and hotspots to identify the causing agents and to take immediate steps for control of high outbreak of Viral Hepatitis. | 2022-02-11T23:18:02.864Z |
11,545,391 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.9790/0853-131234345",
"MAG": "1963995715",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.9790/0853-131234345"
} | Prospective study of 26 patients of proximal humeral fracture admitted in the Department of Orthopaedics between June 2011 to December 2013 whether treated by conservative or surgical method were included in the study. Patients were evaluated for functional result by using The Swanson Shoulder Score and Constant Scoring System (Modified). Final outcome as per Swanson's Shoulder score and modified Constant score was maximum in surgically managed group. With good success rate the indications of operative treatment must be adhered to. The successful results can be attributed to early surgery, good preoperative planning, minimal soft tissue dissection, stable reduction; supervised postoperative exercise and regular follow up. | 2022-06-26T04:58:57.149Z |
118,899,755 | {
"externalids": {
"ACL": null,
"ArXiv": "nucl-th/0605067",
"DOI": "10.1142/9789812706881_0003",
"MAG": "1998541052",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://arxiv.org/pdf/nucl-th/0605067"
} | The four-body bound state with two-body forces is formulated by the Three-Dimensional approach, which greatly simplifies the numerical calculations of few-body systems without performing the Partial Wave components. We have obtained the Yakubovsky equations directly as three dimensional integral equations. | 2022-09-21T19:37:12.503Z |
27,269,799 | {
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/CIRCULATIONAHA.113.006093",
"MAG": "2154860928",
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},
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"url": null
} | Chest compressions are rarely needed in newly born infants, with an estimated occurrence of 0.08% for near-term and term deliveries; however, the consequences of a hypoperfused state on the brain and other organ systems can be devastating.1 Newborns that require prolonged cardiac compressions with no signs of life beyond 10 minutes are at risk for exceptionally poor outcomes, with up to 83% mortality and 77% severe disability noted in survivors.2 Although initiation of therapeutic hypothermia appears to have some advantage for cardiopulmonary resuscitation (CPR) recipients who survive the delivery room,3 optimization of the hemodynamics of neonatal cardiac compressions during CPR remains critical.
Article see p 2495
The infrequent use of cardiac compressions for newborns in the delivery room has impeded the design and completion of rigorous investigations to determine the most effective neonatal cardiac compression methodologies.4 The unique physiology of the … | 2022-12-17T01:46:21.420Z |
123,788,659 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1017/S0305004100056358",
"MAG": "2164762736",
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},
"license": null,
"status": null,
"url": null
} | In our previous consideration in (1) of the constant-coefficient fifth-order differential equation: an attempt was made to identify (though not exhaustively) different sufficient conditions on a1,…,a5 for the instability of the trivial solution x = 0 of (1·1). It was our expectation that the conditions so identified could be generalized in some form or other to equations (1·1) in which a1,…,a5 were not necessarily constants, thereby giving rise to instability theorems for some non-linear fifth-order differential equations; and this turned out in fact to be so except only for the case: with R0 = R0(a1, a2, a3, a4) > 0 sufficiently large, about which we were unable at the time to derive any worthwhile generalization to any equation (1·1) in which a1, …,a5 are not all constants. | 2022-12-17T12:08:40.506Z |
4,390,314 | {
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/eurheartj/ehn363",
"MAG": "2154555604",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
} | AIMS
To evaluate the role of novel biomarkers in early detection of acute myocardial infarction (MI) in patients admitted with acute chest pain.
METHODS AND RESULTS
A prospective study of 664 patients presenting to two coronary care units with chest pain was conducted over 3 years from 2003. Patients were assessed on admission: clinical characteristics, ECG (electrocardiogram), renal function, cardiac troponin T (cTnT), heart fatty acid binding protein (H-FABP), glycogen phosphorylase-BB, NT-pro-brain natriuretic peptide, D-dimer, hsCRP (high sensitivity C-reactive protein), myeloperoxidase, matrix metalloproteinase-9, pregnancy associated plasma protein-A, soluble CD40 ligand. A > or = 12 h cTnT sample was also obtained. MI was defined as cTnT > or = 0.03 microg/L. In patients presenting <4 h of symptom onset, sensitivity of H-FABP for MI was significantly higher than admission cTnT (73 vs. 55%; P = 0.043). Specificity of H-FABP was 71%. None of the other biomarkers challenged cTnT. Combined use of H-FABP and cTnT (either one elevated initially) significantly improved the sensitivities of H-FABP or cTnT (85%; P < or = 0.004). This combined approach also improved the negative predictive value, negative likelihood ratio, and the risk ratio.
CONCLUSION
Assessment of H-FABP within the first 4 h of symptoms is superior to cTnT for detection of MI, and is a useful additional biomarker for patients with acute chest pain. | 2022-12-22T17:25:03.232Z |
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