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124,857,559 | {
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"DOI": "10.1080/10407782.2015.1090834",
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} | ABSTRACT Numerical investigations on the thermal and hydraulic characteristics of pulsating laminar flow in a three-dimensional helical microchannel heat sink (HMCHS) model are performed using Al2O3-water-based nanofluid. The simulation is performed in the laminar regime for Reynolds number ranging from 6 to 25. The two-phase mixture model with modified effective thermal conductivity and viscosity equations is employed to solve the problem numerically. The detailed results for thermal and flow fields are reported for the effects of amplitude (1–3), frequency (5–20 rad/s), and nanoparticle concentration (1%–3%). The results indicate that the heat transfer performance improves significantly for sinusoidal velocity inlet conditions compared with steady flow conditions. | 2022-12-13T19:26:27.222Z |
16,344,606 | {
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"DOI": "10.1596/27585",
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"url": "http://pdfs.semanticscholar.org/8085/47594773fc6b3188dd1f452f5317734d0266.pdf"
} | This report is the final product of a follow-up study undertaken after the completion of the comparative analysis of organization and performance of cotton sectors in Sub-Saharan Africa, a study published by the World Bank in 2008. The objective of this complementary study is to assess the advantages and disadvantages of the main available technologies to separate the lint from the raw cotton, roller ginning and saw ginning, and carry out an economic analysis of the respective benefits of these two technologies for cotton producing countries of Sub-Saharan Africa. The study shows that the choice of ginning technology is an important factor of performance and is in turn influenced by the cotton sector structure. The type of ginning technology also has an impact on lint quality, and, as roller ginning is less damaging to the fiber than saw ginning, it can generate a price premium. The overall economic advantage of roller gins vs. saw gins appears to be significant in the Sub-Saharan African context, and likely to increase in the future as the demand for quality is becoming more and more stringent. Thus, although there are technical and organizational issues to address in order to fully capture the benefits of the technology, the introduction of roller ginning is likely to improve the competitiveness of African cotton and facilitate the transition towards more competitive cotton sectors. | 2022-12-19T09:36:43.890Z |
93,609,117 | {
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"DOI": "10.1021/JP001041K",
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} | The C2H5• + O2 reaction, central to ethane oxidation and thus of fundamental importance to hydrocarbon combustion chemistry, has been examined in detail via highly sophisticated electronic structure methods. The geometries, energies, and harmonic vibrational frequencies of the reactants, transition states, intermediates, and products for the reaction of the ethyl radical (X 2A‘) with O2 (X 3 , a 1Δg) have been investigated using the CCSD and CCSD(T) ab initio methods with basis sets ranging in quality from double-zeta plus polarization (DZP) to triple-zeta plus double polarization with f functions (TZ2Pf). Five mechanisms (M1−M5) involving the ground-state reactants are introduced within the context of previous experimental and theoretical studies. In this work, each mechanism is systematically explored, giving the following overall 0 K activation energies with respect to ground-state reactants, Ea(0 K), at our best level of theory: (M1) direct hydrogen abstraction from the ethyl radical by O2 to give e... | 2022-12-20T15:52:54.933Z |
20,846,763 | {
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"DOI": "10.2174/138920101705160303163947",
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} | In Biotechnology, the expression of recombinant proteins is a constantly growing field and different hosts are used for this purpose. Some valuable proteins cannot be produced using traditional systems. Insects from the order Lepidoptera infected with recombinant baculovirus have appeared as a good choice to express high levels of proteins, especially those with post-translational modifications. Lepidopteran insects, which are extensively distributed in the world, can be used as small protein factories, the new biofactories. Species like Bombyx mori (silkworm) have been analyzed in Asian countries to produce a great number of recombinant proteins for use in basic and applied science and industry. Many proteins expressed in this larva have been commercialized. Several recombinant proteins produced in silkworms have already been commercialized. On the other hand, species like Spodoptera frugiperda, Heliothis virescens, Rachiplusia nu, Helicoverpa zea and Trichoplusia ni are widely distributed in both the occidental world and Europe. The expression of recombinant proteins in larvae has the advantage of its low cost in comparison with insect cell cultures. A wide variety of recombinant proteins, including enzymes, hormones and vaccines, have been efficiently expressed with intact biological activity. The expression of pharmaceutically proteins, using insect larvae or cocoons, has become very attractive. This review describes the use of insect larvae as an alternative to produce commercial recombinant proteins. | 2022-12-21T02:06:50.306Z |
39,937,517 | {
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"DOI": "10.1142/9789814355537_0042",
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} | Abstract : A depth-averaged 2-D model has been developed for simulating coastal barrier breaching processes. The model solves the generalized shallow water equations and the non-equilibrium sediment transport and bed change equations in a coupled fashion using an explicit finite volume method on a rectangular grid. It considers interactions among transient flow, strong sediment transport, and rapid bed change by including bed change and variable flow density in the flow continuity and momentum equations. The model adopts the HLL approximate Riemann solver to handle the mixed-regime flows near the breach and the wetting-drying problem. The developed model has been tested against a lab experiment of dike-break flow over movable bed and a field experiment of sea dike breaching. The simulation results demonstrate that the model is capable of calculating the initial development stage of coastal barrier breaching under supercritical flow. Future work will improve the model to include waves for more general application in the coastal context. | 2022-12-29T20:18:00.914Z |
3,715,184 | {
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"DOI": "10.1093/nar/gkw330",
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"license": "CCBYNC",
"status": "GOLD",
"url": "https://doi.org/10.1093/nar/gkw330"
} | Defining syntenic relationships among orthologous gene clusters is a frequent undertaking of biologists studying organismal evolution through comparative genomic approaches. With the increasing availability of genome data made possible through next-generation sequencing technology, there is a growing need for user-friendly tools capable of assessing synteny. Here we present SimpleSynteny, a new web-based platform capable of directly interrogating collinearity of local genomic neighbors across multiple species in a targeted manner. SimpleSynteny provides a pipeline for evaluating the synteny of a preselected set of gene targets across multiple organismal genomes. An emphasis has been placed on ease-of-use, and users are only required to submit FASTA files for their genomes and genes of interest. SimpleSynteny then guides the user through an iterative process of exploring and customizing genomes individually before combining them into a final high-resolution figure. Because the process is iterative, it allows the user to customize the organization of multiple contigs and incorporate knowledge from additional sources, rather than forcing complete dependence on the computational predictions. Additional tools are provided to help the user identify which contigs in a genome assembly contain gene targets and to optimize analyses of circular genomes. SimpleSynteny is freely available at: http://www.SimpleSynteny.com. | 2022-12-30T18:32:05.748Z |
55,427,748 | {
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"DOI": "10.5539/EP.V1N1P29",
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} | Cd, Cr, Cu, Fe, Ni, Pb, and Zn were measured in feathers from male and female White-chinned petrels Procelllaria aequinoctialis accidentally killed in longliners off Argentina in 2005. Cd, Pb, and Ni concentrations in adult feathers were below detection limits regardless of the birds' sex. Metal concentrations did not vary with sex for Cu, Fe and Zn in feathers of adult birds despite significant differences in body size between males and females. The Cu and Fe concentrations differed significantly between the type of feather within individual birds. The mean concentrations of metals determined here were within the range of concentrations reported in feather tissues of other related Procellariiformes species from different biogeographic areas. However, the concentrations of Cr were similar to those reported for other petrels from polluted areas of the North Pacific. Thus, it appears likely that levels of pollution in Patagonia may not be as negligible as previously thought for some trace metals. | 2022-10-14T00:32:53.441Z |
1,227,990 | {
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"DOI": "10.1145/1498765.1498802",
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} | In June 2005, a unIt of LexIs-nexIs dIscovered the theft of 310,000 customer records containing sensitive information such as customer names, addresses, social security numbers, and driver's license numbers. 5 This incident followed closely on the occasion of ChoicePoint's disclosure of the theft of personally identifiable information (PII) of hundreds of thousands of customers and Bank of America's declaration that it lost backup tapes containing information on 1.2 million customers. 16 Given the seriousness of the matter, firms are struggling with finding ways to best ensure the privacy of their customer's and employees' sensitive data. Regulatory systems, especially those in the U.S., have been very active in the past four years in trying to find ways to combat such problems; for example, in mid-2002, as many as 80 privacy laws were being considered by the U.S. Congress. Such highly publicized laws as HIPPA, Sarbanes-Oxley, and the Gra-ham-Leach-Bliley Act have profoundly changed the firm's responsibilities to protect the privacy of information of its key stakeholders. However, laws and technology alone cannot ensure the implementation of safe privacy policies ; Vijayan 13 discusses a number of difficulties in applying new technologies and inventing new business practices to monitor and ensure privacy compliance, respecting stakeholder privacy choices, and overseeing the privacy practices of business suppliers, partners, and vendors. Therefore, privacy is viewed by many organizations as a vital management issue , shaped by a complex environmental factors emanating from economic, political, social and technological factors. Recently, a number of firms and public sector entities began to address the issue of privacy in a more radical way through the creation of a new corporate wide job function—that of chief privacy officer (CPO). A number of academic and practitioners attribute the emergence of this position to a public awareness of privacy. 10 The position of the CPO is a relatively new one; the first CPO being hired in 1999. 1 Given the novelty of this position, it can be expected that one finds most of the CPO literature to be prescriptive in nature. Some describe the key functions of the CPO, and others look into the required capabilities and competencies of the position. To the best of our knowledge , no study has investigated the level of concentration of CPOs in specific industries; such as, why some organizations decide to create a CPO position while others, decide against it. This study addresses the CPO concentration … | 2022-11-14T15:12:09.014Z |
128,470,836 | {
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"DOI": "10.1130/G25106A.1",
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} | Earthworms of the family Lumbricidae, which includes many common species, produce and secrete up to millimeter-sized calcite granules, and the intricate fine-scale zoning of their constituent crystals is unique for a biomineral. Granule calcite is produced by crystallization of amorphous calcium carbonate (ACC) that initially precipitates within the earthworm calciferous glands, then forms protogranules by accretion on quartz grain cores. Crystallization of ACC is mediated by migrating fluid films and is largely complete within 24 h of ACC production and before granules leave the earthworm. Variations in the density of defects formed as a byproduct of trace element incorporation during calcite crystal growth have generated zoning that can be resolved by cathodoluminescence imaging at ultraviolet to blue wavelengths and using the novel technique of scanning electron microscope charge contrast imaging. Mapping of calcite crystal orientations by electron backscatter diffraction reveals an approximate radial fabric to the granules that reflects crystal growth from internal nucleation sites toward their margins. The survival within granules of ACC inclusions for months after they enter soils indicates that they crystallize only within the earthworm and in the presence of fluids containing biochemical catalysts. The earthworm probably promotes crystallization of ACC in order to prevent remobilization of the calcium carbonate by dissolution. Calcite granules vividly illustrate the role of transient precursors in biomineralization, but the underlying question of why earthworms produce granules in volumes sufficient to have a measurable impact on soil carbon cycling remains to be answered. | 2022-12-13T09:03:47.751Z |
126,238,636 | {
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"DOI": "10.1175/BAMS-D-16-0133.1",
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} | AbstractTropical cyclone (TC) track forecasts of operational numerical weather prediction (NWP) models have been compared and verified by the Japan Meteorological Agency (JMA) under an intercomparison project of the Working Group on Numerical Experimentation (WGNE) since 1991. This intercomparison has promoted validation of the global models in the tropics and subtropics. The results have demonstrated a steady increase in the global models’ ability to predict TC positions over the past quarter century.The intercomparison study started from verification for TCs in the western North Pacific basin with three global models. Up to the present date, the verification has been extended to all ocean basins where TCs regularly occur, and 12 global models participated in the project. In recent years, the project has been extended to include verification of intensity forecasts and forecasts by regional models.This intercomparison project has seen a significant improvement in TC track forecasts, both globally and in e... | 2022-12-15T09:22:58.801Z |
1,130,270 | {
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"DOI": "10.1097/00001756-200212200-00006",
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} | This study aimed to test mechanisms underlying impairments in balance control in children with cerebral palsy. We hypothesized that balance loss during large/fast perturbations could be due to reduced contraction of agonist muscles, delay in muscle contraction or simultaneous contraction of antagonist muscles, reducing the efficiency of the agonist burst. Electromyograms were recorded as children recovered from balance threats of varying magnitudes/velocities. In typically developing children muscle response magnitudes increased with larger/faster perturbations, while in children with cerebral palsy they did not. There was no difference in muscle onset latency or antagonist co-contraction between groups. Thus the primary constraint on balance recovery in these children is insufficient levels of contraction of agonist postural muscles. | 2022-12-18T21:01:21.774Z |
83,742,921 | {
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"DOI": "10.1515/mamm.2003.67.1.109",
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} | Les relations phylogenetiques de plusieurs sous-especes d'Ovis ammon ont ete analysees en comparant les sequences d'ADN de la D-loop. Cinq sous-especes probables d'O. ammon (dalai-lamae, darwini, hodgsoni, sairensis et adametzi) ont ete echantillonnees de quatre provinces de Chine: Xinjiang, Qinghai, Gansu et Xizang (Tibet), et deux (servertzovi et nigrimontana) d'Ouzbekistan. Les argalis analyses representent la plupart des sous-especes actuellement reconnues d'argalis. L'analyse des sequences de mtDNA a revele la haute variabilite intraspecifique (7.7%), et specifique (2.4 a 11.5%). L'analyse en parcimonie a indique une premiere divergence de nigrimontana d'Ouzbekistan, suivie par severtzovi d'Ouzbekistan. La dispersion des argalis dans la Chine a engendre trois clades, ce qui suggere que les argalis seraient originaires de l'ouest de l'Asie et qu'ils se seraient disperses rapidement a travers les montagnes d'Asie centrale vers le sud-est. Entre les argalis chinois, l'analyse de mtDNA place la sous espece dalai-lamae plus pres d'hodgsoni que de darwini. Severtzovi et nigrimontana sont deux sous-especes genetiquement distinctes, separees genetiquement des argalis chinois. | 2022-12-18T09:41:26.193Z |
32,254,046 | {
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"DOI": "10.1093/INTIMM/12.11.1539",
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} | Dendritic cells (DC) are key components of innate and adaptive immune responses. The identity of endogenous signals that activate DC is a crucial and unresolved question. We report here that heat shock proteins (HSP), the most abundant and conserved mammalian molecules, constitute such an internal signal. Necrotic but not apoptotic cell death leads to release of HSP gp96, calreticulin, hsp90 and hsp70. HSP stimulate macrophages to secrete cytokines, and induce expression of antigen-presenting and co-stimulatory molecules on the DC. The HSP gp96 and hsp70 act differentially, and each induces some but not all molecules. HSP interact with these antigen-presenting cells through the highly conserved NF-kappa B pathway. As HSP are intracellular, abundant and soluble, their presence in the extra-cellular milieu and the consequent activation of antigen-presenting cells (APC) constitutes an excellent mechanism for response to cell death. As HSP are conserved from bacteria to mammals, the ability of HSP to activate APC provides a unified mechanism for response to internal and external stimuli. | 2023-01-01T17:28:38.989Z |
221,798,077 | {
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"DOI": "10.1089/hs.2020.0062",
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} | In Morocco, as in many countries, COVID-19 spread nationwide causing a public health emergency. Strict quarantine measures implemented as a result of the pandemic have disrupted many aspects of people's lives, triggering psychological distress. A total of 256 participants were recruited through a convenience sample. Data were collected through snowball sampling, an assessment of distress symptoms using the Brief Symptoms Inventory, and an assessment of leisure-time physical activity using the Godin-Shephard Leisure-Time Physical Activity Questionnaire. Bivariate and multivariate analyses were performed. Significant changes in paranoid ideation (z = -2.45, P = .01) and interpersonal sensitivity (z = -2.01, P = .04) dimensions were noted between those who were and those who were not authorized to leave their homes during quarantine. Similarly, for physical activity, significant changes in depression (z = -2.15, P = .03), anxiety (z = -2.13, P = .03), interpersonal sensitivity (z = -1.95, P = .05), and somatization (z = -2.11, P = .03) were reported among the insufficiently active group compared with the more physically active group. From multiple regression analysis, variables correlated with general distress were type of quarantine, gender, age, education level, chronic disease, and smoking (R2 = .80). With some variables, leisure-time physical activity domains appeared to be associated only with interpersonal sensitivity and somatization. Having to leave one's home during the outbreak was linked to distress, especially symptoms like suspiciousness, hostility, fearful thoughts of losing autonomy, and feelings of inadequacy, uneasiness, and discomfort during interpersonal interactions. Individuals who were moderately or sufficiently active physically reported less psychological distress. | 2022-12-29T18:15:35.699Z |
117,935,536 | {
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"DOI": "10.1017/CBO9780511755590",
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} | Differential geometry plays an increasingly important role in modern theoretical physics and applied mathematics. This textbook gives an introduction to geometrical topics useful in theoretical physics and applied mathematics, including manifolds, tensor fields, differential forms, connections, symplectic geometry, actions of Lie groups, bundles and spinors. Having written it in an informal style, the author gives a strong emphasis on developing the understanding of the general theory through more than 1000 simple exercises, with complete solutions or detailed hints. The book will prepare readers for studying modern treatments of Lagrangian and Hamiltonian mechanics, electromagnetism, gauge fields, relativity and gravitation. Differential Geometry and Lie Groups for Physicists is well suited for courses in physics, mathematics and engineering for advanced undergraduate or graduate students, and can also be used for active self-study. The required mathematical background knowledge does not go beyond the level of standard introductory undergraduate mathematics courses. | 2022-12-30T00:37:31.027Z |
219,116,183 | {
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"DOI": "10.33153/iicacs.v2i1.20",
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"url": "https://conference.isi-ska.ac.id/index.php/iicacs/article/download/20/17"
} | Sundanese script is a system for writing Sundanese. The traditional writing system in Sundanese began in the 14th century until the 19th century. Sundanese script is related to cosmology that developed in Sundanese society. This research will review the role of technology in transforming local values by comparing the Ancient Sundanese Script and the Modern Sundanese Script through ATUMICS method. The result of this study shows that there is a simplification happening when transforming the Ancient Sundanese Script to the Modern ones. However, the Sundanese cosmology embodied within the Sundanese script is not lost. Thus, the transformation of tradition could become one of the options in preserving local traditional values while adapting it into the current world. | 2022-09-08T20:56:22.850Z |
73,785,293 | {
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"DOI": "10.6557/GJTa.199203_9(1).0004",
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} | According to past epidemiological. investigation, more than 90% of adults in Taiwan had type A viral hepatitis. However, a decline in the positive rate of anti-HAV in adults was also found in recent years. Therefore, HAV infection is still a problem in our area. Type B viral hepatitis is endemic to Taiwan with a HBV carrier rate of 15-20%. The main purpose of this study is to discover whether or not the clinical and biochemical pictures are different when the HBs Ag carriers superinfect with an acute type A viral hepatitis. Sixty-one cases with acute type A viral hepatitis were analyzed from 1981 to 1990 at Tri-Service General Hospital. The diagnostic criteria of acute type A viral hepatitis were confirmed by positive 1gM-anti-HA V. There were 35 males and 26 females, aged from 4 to 73 years old. The peak age ranged from 16 to 25 years. Among these 61 cases, 50 cases (81.9%) were HBs Ag negative, 11 cases (18.1%) were HBs Ag positive, an incidence similiar to that in the general population of Taiwan. Their clinical and biochemical pictures were identical with the HBs Ag negative patients except for a significant elevation of AST, ALT, and total bilirubin in HBs Ag non-carriers (P＜0.01 and ＜0.05). This indicates that HBs Ag negative patients had more severe damage of liver cells but their hepatic recovery is rather faster than those of HBs Ag positive patients. No evidence of continued inflammation or chronic hepatitis was demonstrated in the follow-up study. | 2022-02-11T08:39:13.518Z |
40,235,919 | {
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"DOI": "10.1001/JAMA.1979.03300120027018",
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} | In a series of 14,077 hospitalized medical patients receiving antibiotics, superinfection developed in 95 (0.7%) during drug therapy. The majority were yeast and fungal infections, and serious infections occurred with a frequency of less than one per 1,000 patients treated. Concurrent immunosuppression and impaired renal function increased the risk of new infections. | 2022-09-11T05:39:36.348Z |
205,367,095 | {
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"DOI": "10.1096/fj.10-169995",
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"url": "https://europepmc.org/articles/pmc3058710"
} | Throughout spermatogenesis, the Sertoli cell blood‐testis barrier (BTB) is strictly regulated by cytokines, which mediate its timely restructuring, thereby allowing spermatocytes to enter the adluminal compartment of the seminiferous epithelium for development into spermatozoa. The aim herein was to investigate whether germ cells play a role in BTB restructuring via the action of interleukin‐lo (IL‐1α) since germ cells are known to control Sertoli cell production of this cytokine, and if yes, how these effects are mediated. When Sertoli cells were isolated from Sprague‐Dawley rats and plated at high density, IL‐1α (100 pg/ml) was shown to “open” the Sertoli cell barrier when its integrity was assessed by transepithelial electrical resistance measurements. Further investigation of Sertoli cells treated with IL‐1α revealed striking changes in the cellular distribution of actin filaments when compared to untreated cells. These effects at the Sertoli cell barrier were mediated, in part, by epidermal growth factor receptor pathway substrate 8 (Eps8; an actin bundling and barbed‐end capping protein) and actin‐related protein 3 (Arp3; a component of the actin nucleation machinery). As important, an increase in the kinetics of occludin internalization but a decrease in its rate of degradation was noted following IL‐1α treatment. These results indicate that IL‐1α is a critical regulator of BTB dynamics.—Lie, P. P. Y., Cheng, C. Y., Mruk, D. D. Interleukin‐lα is a regulator of the blood‐testis barrier. FASEB J. 25, 1244–1253 (20ll) (2011). www.fasebj.org | 2022-12-21T10:23:50.536Z |
6,205,232 | {
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} | 1. MOTIVATION AND SUMMARY Traditional Database Management Systems (DBMS) software is built on the concept of persistent data sets, that are stored reliably in stable storage and queried/updated several times throughout their lifetime. For several emerging application domains, however, data arrives and needs to be processed on a continuous ( ) basis, without the benefit of several passes over a static, persistent data image. Such continuous data streams arise naturally, for example, in the network installations of large Telecom and Internet service providers where detailed usage information (Call-Detail-Records (CDRs), SNMP/RMON packet-flow data, etc.) from different parts of the underlying network needs to be continuously collected and analyzed for interesting trends. Other applications that generate rapid, continuous and large volumes of stream data include transactions in retail chains, ATM and credit card operations in banks, financial tickers, Web server log records, etc. In most such applications, the data stream is actually accumulated and archived in the DBMS of a (perhaps, off-site) data warehouse, often making access to the archived data prohibitively expensive. Further, the ability to make decisions and infer interesting patterns on-line (i.e., as the data stream arrives) is crucial for several mission-critical tasks that can have significant dollar value for a large corporation (e.g., telecom fraud detection). As a result, recent years have witnessed an increasing interest in designing data-processing algorithms that work over continuous data streams, i.e., algorithms that provide results to user queries while looking at the relevant data items only once and in a fixed order (determined by the stream-arrival pattern). Two key parameters for query processing over continuous datastreams are (1) the amount of memory made available to the online algorithm, and (2) the per-item processing time required by the query processor. The former constitutes an important constraint on the design of stream processing algorithms, since in a typical streaming environment, only limited memory resources are available to the query-processing algorithms. In these situations, we need algorithms that can summarize the data stream(s) involved in a concise, but reasonably accurate, synopsis that can be stored in the allotted (small) amount of memory and can be used to provide approximate answers to user queries along with some reasonable guarantees on the quality of the approximation. Such approx- | 2022-12-24T20:50:06.338Z |
97,702,116 | {
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"DOI": "10.3769/RADIOISOTOPES.59.441",
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} | 反強磁性層と強磁性層の積層界面に働く交換結合力は，強磁性層の磁化曲線に，交換バイアスと呼ばれるシフトを生じさせる。新しい材料であるMnIr/CoFe積層膜は，薄い膜厚でも大きい交換バイアスを発生することができるため，磁気記録デバイス用として注目されている。筆者らは，この積層膜の磁気構造を，SPring-8におけるX線共鳴磁気反射率測定及び，日本原子力研究開発機構(JAEA)の中性子施設JRR-3における偏極中性子反射率測定により調べた。これらの測定からは，界面でのスピンの固着成分と回転成分の元素選択的な評価と，強磁性層の磁化ベクトルの回転角が得られた。これらの実験結果から，MnIr/CoFe交換結合膜中でのスピンの分布と，交換バイアスとの関係を議論する。 | 2022-06-20T08:19:37.684Z |
96,360,195 | {
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"DOI": "10.1039/C39850000030",
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} | Flash photolysis of Cr(CO)6 in H2-saturated cyclohexane Solution leads to the formation of Cr(CO)5(H2) as a relatively stable transient (k= 2.5 s–1 at room temperature); Cr(CO)5(H2) is identified by kinetic i.r. spectroscopy, including D2 isotpe effects. | 2022-09-15T06:39:41.793Z |
20,025,074 | {
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"DOI": "10.1111/j.1537-2995.2012.03935.x",
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} | The American Red Cross began preferentially distributing plasma from male donors in 2007 and subsequently observed an 80% decrease in reported cases of transfusion‐related acute lung injury (TRALI) after plasma transfusion. Plasma distributions from male donors now exceed 99% for groups A, B, and O, but only approximately 60% for group AB. We evaluated the ongoing risk of TRALI and the ABO blood group of involved plasma donors. | 2022-12-19T07:53:45.089Z |
145,359,710 | {
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"DOI": "10.1080/00263200500521370",
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} | Although there has not yet appeared an internationally recognized definition, the concept of ‘minority’ has traditionally been associated with those objective elements of citizenship, common ethno-cultural and linguistic heritage, and of subjective elements including having a sense of communal solidarity and willingness to preserve group-specific particularities. In other words, minority peoples have indicated those sections of national citizens who manifested ethno-cultural, linguistic and religious distinctions in respect of the mainstream identity category of the country’s majority population. Accordingly, the legal–political status of minority peoples in modern conditions has been based on two sources of citizenship and ethno-cultural distinctions. Individual equality and non-discrimination have constituted the foundational basis of the principle of citizenship which has inherently been associated with the principle of formal or universal equality that indicated a certain form of legal– political status having nothing to do with peoples’ particularities. Whether they belonged to majority or minority sections of the population, individual citizens have been subjected, in principle, to the same civil and political rights and freedoms. In so doing, however, citizenship practices have tended to abstract individuals from their ethno-cultural circumstances. Beyond doubt, legal equality is the sine qua non of citizenship status, but legal equality in itself is not sufficient to guarantee achievement of genuine equality, particularly in those social circumstances where population displayed ethno-cultural diversity. It is because of this that treating essentially different groups in an identical fashion, that is, treating minority groups in the same manner as the majority, has equally tended to violate principles of both equality and non-discrimination. Putting the matter differently, the principle of citizenship equality in culturally diverse societies calls for accommodating both similar and distinct circumstances of peoples. Having pointed out the fact that a theory and practice of equality ‘grounded in human uniformity is both philosophically incoherent and morally problematic’, Parekh suggested that ‘human beings are at once both natural and cultural beings’, that is ‘they are both similar and different . . .We cannot ground equality in human uniformity’, because, ‘while granting them equality at the level of their shared human nature, we deny it at the equally important cultural level’. For Parekh, only when we break the traditional equation of equality with similarity, the principle of equality would ‘require us to take into account both their similarities and differences’. Middle Eastern Studies, Vol. 42, No. 3, 447 – 468, May 2006 | 2022-12-24T20:27:10.057Z |
158,940,254 | {
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"url": "https://doisrpska.nub.rs/index.php/socioloskidiskurs/article/download/4457/4279"
} | Death is an infallible part of the human life, and what makes human different from all other beings is fact that he knows that he is going to die. Knowing this, human beings are spending their whole life knowing that the day of their end is going to come. It is clear that death has its biological part, also as a huge event in the existence of all life forms, including human, death has its philosophical point of view, and finally, unlike some may disagree, death itself is a huge social phenomena as well, and as such, the social influence of death deserves close attention and its own part in the social science studies. This paper analyzes the presence of the death in human culture, including institutions, rituals and beliefs following the discourse of late Zygmunt Bauman who left huge influence on this field of study. Since the earliest forms of communities, humans are trying to overcome the death, the state of “after-life” and some form of immortality of the being is something that is common to all religions and beliefs ever known to mankind, which stands as a evidence that the final void of non-existence know to us as death is something that always presented horror in the mind of the humans. | 2022-02-08T23:28:39.978Z |
149,624,189 | {
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"DOI": "10.1177/1097184X18775468",
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} | Expansion of global production in the automotive industry has made America’s local plants increasingly racially varied but also more financially pressured. However, research on global firms under financial pressure that focuses on the workplace dynamics of managers and production workers of different races and nationalities remains limited. This article examines the organizational processes of masculinity enactment of three groups of men—Japanese managers, American managers, and American production workers—in a financially pressured Japanese auto-parts company. It describes how Japanese managers rationalized account manipulation as a profit recovery scheme and American workers validated this approach as being self-sacrificing and representative of heroic leadership; white American managers asserted their authority over engineers, women, and Japanese men by using intimidation and emasculation; and a production worker displayed his compensated masculinity by forcing his team to engage in hiding defective products. This article discusses the implications of these acts and their legitimization of unethical behaviors with the goal of increasing corporate profits from the perspectives of masculinities and of management. | 2022-02-09T04:16:44.191Z |
242,102,201 | {
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"DOI": "10.12660/rbfin.v15n2.2017.67390",
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"url": "https://doi.org/10.12660/rbfin.v15n2.2017.67390"
} | The present study analyses the effect of trade volume on market
analysts’ purchase and sell recommendation choices. The research analyses
7,293 consensus recommendations regarding Brazilian listed companies for the
period 2008-2014. Sample data includes firms’ fundamentalist
characteristics, as total assets, return, net income and dividends, with the
objective to identify the factors taken under account by analysts for their
recommendation evaluations. Applying unbalanced panel data regression
strategy, we find that analysts prefer to recommend shares with higher
observed trading volume, and the shares with more favourable evaluations are
those with higher observed trading volume, which is agreeing with
theoretical expectations. Other significative covariates for recommendations
are the earnings before interests and taxes – EBIT, return per share, return
of assets – ROA, paid dividends, and the price/equity ratio. | 2022-02-25T00:33:10.951Z |
10,428,675 | {
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"DOI": "10.1109/MTITS.2015.7223286",
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} | An intelligent device system for the automatic notification of traffic code violations is proposed. Then an analysis of the demand potentially interested in the new system is conducted based on both random utility and neural networks models. | 2022-05-28T14:25:22.458Z |
10,416,202 | {
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"DOI": "10.1111/j.1600-0609.2005.00563.x",
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} | Abstract: We present a case of intracellular vitamin B12 deficiency presenting with confusion, subacute combined degeneration of the cord, megaloblastic anaemia and intrinsic factor antibodies in the serum. Diagnosis was delayed by a normal serum B12 level and was confirmed by a grossly elevated serum homocysteine. There was a dramatic response to steroids. The patient was heterozygous for the transcobalamin (TC) II polymorphism 776C→G. This case demonstrates the importance of functional assessment of intracellular B12 activity (e.g. serum homocysteine) in excluding B12 deficiency, the role of steroids in pernicious anaemia and a possible clinical correlation of a TCII polymorphism. | 2022-07-27T01:47:20.921Z |
43,537,809 | {
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"DOI": "10.1111/j.1464-5491.1985.tb00594.x",
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} | The feasibility and effects of changeover from traditional to modern methods of diabetic management in insulin‐dependent diabetics (IDDs) are described. Patients were asked to switch from urine testing to home blood glucose monitoring, from carbohydrate restricted to high carbohydrate‐high fibre diets and from one to two injections of insulin per day with the help of a diabetic education sister. Most patients (81%) changed immediately to blood glucose monitoring and after 6 months none wanted to go back to urine tests and 58% changed to a high fibre diet. Subjects in the ‘monitoring’ group had a significant improvement in HbA1 (mean ± S.E.M. 14.1 ± 0.4% to 11.4 ± 0.5% and 11.8 ± 0.5% at 4 and 8 months, respectively, p<0.01), without any increase in frequency of hypoglycaemia, whereas the rest showed no change. No subject was hospitalized for hyperglycaemia. In conclusion, these newer management techniques can be successful in the majority of IDDs. They are easy to apply, highly acceptable and effective. | 2022-09-01T18:53:40.497Z |
238,775,417 | {
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"DOI": "10.1055/a-1467-0665",
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"url": "http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1467-0665.pdf"
} | Schon mehrfach war an dieser Stelle von Fortschritten in der Informationstechnik die Rede, bei denen es um die Resultate der Anwendung künstlicher (d. h. im Computer simulierter) neuronaler Netzwerke auf reale Probleme ging. Diese Arbeiten sind zuweilen spektakulär und werden nicht zuletzt deswegen in den bedeutendsten wissenschaftlichen Fachblättern publiziert. Vor einem halben Jahrzehnt beispielsweise hatte ein solches Netzwerk an Beispielen gelernt, das komplexeste Brettspiel der Welt – Go mit seinen 10171 möglichen Kombinationen1 – zu spielen. Es war also kein Programm geschrieben worden, das Go spielen konnte; vielmehr lernte ein Computer, der künstliche Neuronen und Synapsen simulierte (man nannte das System Alpha-Go), durch das Nachspielen publizierter Go-Partien dieses Spiel und gewann danach vier von fünf Spielen gegen Lee Sedol, den damals weltbesten Go-Spieler, wie das Fachblatt Nature berichtete [26]. Nur eineinhalb Jahre später erschien – ebenfalls in Nature – eine Arbeit zu einem neueren neuronalen Netzwerk (genannt Alpha-Go zero), das gleichsam bei „Null“ mit dem Lernen begonnen hatte (daher der Name) und von Anfang an nur gegen sich selbst spielte. Innerhalb von 3 Tagen durchlief es 3000 Jahre Go-Geschichte (d. h. entdeckte beispielsweise Eröffnungen und Endspiele, für deren Entdeckung die Go-spielenden Menschen 3 Jahrtausende gebraucht hatten) und spielte dann 37 Tage weiter gegen sich selbst auf eine Weise, die für Go-Experten immer unverständlicher wurde, d. h. von ihnen nicht mehr nachvollzogen werden konnte. Danach ließ man Alpha-Go zero 100-mal gegen Alpha-Go (also dasjenige neuronale Netzwerk, das zuvor den weltbesten Spieler besiegt hatte) spielen, wobei Alpha-Go zero 100 Mal gewann [26]. Seither versuchen die weltbesten Go-Spieler, von Alpha-Go zero zu lernen, wie man dieses Spiel besser spielt. Spiele waren jedoch nur der Anfang. Ebenfalls im Jahr 2017 wurde – wieder in Nature – publiziert, dass ein mit entsprechend trainierten neuronalen Netzwerken im Internet verbundenes Smartphone Hautkrebs so gut diagnostizieren kann wie ein Dermatologe. Neuronale Netzwerke finden mittlerweile neue Synthesewege in der Chemie, haben das Problem der Faltung von Eiweißkörpern, völlig neue Erkenntnisse in der Radiologie und vieles mehr an Problemen | 2022-09-30T00:30:27.037Z |
154,040,024 | {
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"DOI": "10.1080/15022250903119546",
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} | Abstract In recent years, events and festivals have been increasingly seen as a good way of developing the regions and the tourism in localities in eastern Finland. In order to be able to produce comparable information on the different impacts of events in Finland, and to gain continuity to event research, a pilot version of a Finnish Event Evaluation Tool (FEET) was created in 2007. The article presents the development of FEET which was piloted in 12 events. The tool is based on former impacts research. It concentrates on evaluating socio‐cultural impacts of events in parallel with economic impacts. Innovative in FEET is the possibility of collecting comparable information from several stakeholder groups at the same time. | 2022-12-09T11:18:19.797Z |
101,245,593 | {
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"DOI": "10.1021/IE404148J",
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} | To cope with computational challenges on dynamic optimization problems with discontinuous control profiles, a methodology combining the adaptive pseudospectral method with the structure detection procedure is presented. First, the adaptive pseudospectral method, which divides time intervals based on an estimation of approximation error, is utilized to obtain potential sequence and type of arcs composed of discontinuous control profiles. Second, the derived information is exploited by the structure detection procedure to reformulate the original nonsmooth problem as a multistage problem (MSP), where adjacent arcs with the same input type are merged into one to remove unnecessary LGR points for the final approximation. Additionally, a stop criterion by monitoring variations of the Hamiltonian function at discrete points is proposed to estimate whether the computed solution satisfies the necessary conditions of optimality in the sense of Pontryagin’s Minimum Principle. The efficiency of the proposed method i... | 2022-12-11T10:50:38.509Z |
188,690,408 | {
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} | espanolObjetivo. Determinar la prevalencia y los factores asociados a publicar articulos cientifi cos en medicos residentes de Peru. Sujetos y metodos. Estudio transversal analitico usando los datos obtenidos por la Encuesta Nacional para Medicos Residentes 2016 (ENMERE-2016), realizada virtualmente durante junio de 2016. Poblacion: los medicos que realizan su residencia en alguna universidad de Peru. Muestra: los residentes que voluntariamente participaron en la ENMERE-2016. Desenlace de interes: autorreporte de haber publicado al menos un articulo cientifi co. Se recogieron variables sociodemograficas, de la universidad, de la sede, de la residencia, de la percepcion del residente y de sintomas depresivos. Para evaluar los factores asociados a haber publicado algun articulo cientifi co se calcularon razones de prevalen crudas ajustadas con sus intervalos de confi anza al 95%. Resultados. Se analizaron datos de 1.062 residentes (42,2% de sexo femenino), de los cuales 118 (11,1%) publicaron algun articulo cientifi co durante la residencia. En el analisis ajustado, cursar los anos superiores de la residencia, haber realizado alguna rotacion externa fuera del pais y tener una puntuacion mas alta en la opinion global del proceso de formacion fueron variables directamente asociadas con haber publicado algun articulo cientifico, en tanto que el sexo femenino, tener mas de 35 anos y presentar sintomas depresivos fueron variables inversamente asociadas a dicho desenlace. Conclusion. Aproximadamente uno de cada 10 residentes publico algun articulo cientifi co durante la residencia. Esto fue menos prevalente en las mujeres, en los residentes de mayor edad, en quienes cursaban anos inferiores de la residencia, en quienes no realizaron ninguna rotacion fuera del pais, en quienes tuvieron una peor opinion del proceso de formacion y en quienes presentaban sintomas depresivos EnglishAim. To determine the prevalence and the factors associated with the publication of scientifi c articles in medical residents of Peru. Subjects and methods. Cross-sectional analytical study using the data obtained by the National Survey for Resident Physicians 2016 (ENMERE-2016), carried out virtually during June 2016. Population: physicians who live in a university in Peru. Sample: residents who voluntarily participated in ENMERE-2016. Outcome of interest: have published at least one scientifi c article. Sociodemographic variables were collected, from the university, from the headquarters, from the residence, from the resident’s perception, and from depressive symptoms. To evaluate the factors associated with having published a scientifi c article, crude and adjusted prevalence ratios were calculated with their 95% confi dence intervals. Results. Data from 1062 residents (42.2% female) were analyzed, of which 118 (11.1%) published some scientifi c paper during the resident. In the adjusted analysis, to study the superior years of residency, to have performed some external rotation outside the country and to have a higher score in the overall opinion of the training process were variables directly associated with having published some scientifi c article. While the female sex, being over 35 years old and presenting with depressive symptoms were variables inversely associated with this outcome. Conclusion. Approximately one in ten residents published a scientifi c article during the residency. This was less prevalent in women, in older residents, in those who were in lower years of residence, in those who did not perform any rotation outside the country, in those who had a worse opinion of the training process, and in those with depressive symptoms. | 2022-12-18T07:38:10.050Z |
42,084,698 | {
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"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/anae.13078"
} | Having inserted a size-4 Visionary LAD (Marshall Airway Products Ltd., Bath, UK) laryngeal mask airway (LMA), we found its lack of flexibility prevented dental surgical access without causing pressure damage to the lower lip. Substitution for a size-3 King LAD (King Systems, Noblesville, IN, USA) resolved this problem. Postoperative examination of the Visionary LMA revealed double the coil count of the King LAD LMA (1 coil.mm 1 vs 0.5 coil.mm , respectively), presumably accounting for the greater turgidity of the former (Fig. 1). Anaesthetists are reminded that visually similar devices can have markedly different properties. T. Knight S. Webster G. M. Haslam Cheltenham General Hospital, Cheltenham, UK Email: [email protected] No external funding and no competing interests declared. | 2022-12-18T22:48:08.102Z |
18,006,773 | {
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"DOI": "10.1074/mcp.M600066-MCP200",
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} | Mapping of in vivo protein phosphorylation sites in photosynthetic membranes of the green alga Chlamydomonas reinhardtii revealed that the major environmentally dependent changes in phosphorylation are clustered at the interface between the photosystem II (PSII) core and its light-harvesting antennae (LHCII). The photosynthetic membranes that were isolated form the algal cells exposed to four distinct environmental conditions affecting photosynthesis: (i) dark aerobic, corresponding to photosynthetic State 1; (ii) dark under nitrogen atmosphere, corresponding to photosynthetic State 2; (iii) moderate light; and (iv) high light. The surface-exposed phosphorylated peptides were cleaved from the membrane by trypsin, methyl-esterified, enriched by immobilized metal affinity chromatography, and sequenced by nanospray-quadrupole time-of-flight mass spectrometry. A total of 19 in vivo phosphorylation sites were mapped in the proteins corresponding to 15 genes in C. reinhardtii. Amino-terminal acetylation of seven proteins was concomitantly determined. Sequenced amino termini of six mature LHCII proteins differed from the predicted ones. The State 1-to-State 2 transition induced phosphorylation of the PSII core components D2 and PsbR and quadruple phosphorylation of a minor LHCII antennae subunit, CP29, as well as phosphorylation of constituents of a major LHCII complex, Lhcbm1 and Lhcbm10. Exposure of the algal cells to either moderate or high light caused additional phosphorylation of the D1 and CP43 proteins of the PSII core. The high light treatment led to specific hyperphosphorylation of CP29 at seven distinct residues, phosphorylation of another minor LHCII constituent, CP26, at a single threonine, and double phosphorylation of additional subunits of a major LHCII complex including Lhcbm4, Lhcbm6, Lhcbm9, and Lhcbm11. Environmentally induced protein phosphorylation at the interface of PSII core and the associated antenna proteins, particularly multiple differential phosphorylations of CP29 linker protein, suggests the mechanisms for control of photosynthetic state transitions and for LHCII uncoupling from PSII under high light stress to allow thermal energy dissipation. | 2022-12-22T16:19:10.993Z |
22,104,613 | {
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"DOI": "10.1103/PhysRevE.65.046417",
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} | A statistical multistream description of quantum plasmas is formulated, using the Wigner-Poisson system as dynamical equations. A linear stability analysis of this system is carried out, and it is shown that a Landau-like damping of plane wave perturbations occurs due to the broadening of the background Wigner function that arises as a consequence of statistical variations of the wave function phase. The Landau-like damping is shown to suppress instabilities of the one- and two-stream type. | 2022-12-26T05:32:52.671Z |
122,096,399 | {
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} | The density of zeros of polynomial solutions of ordinary differential equations of the fourth order with coefficients depending only on the independent variable is analyzed. The first four moments of such a density are given directly in terms of the coefficients which characterize the differential operator. Application to the nonclassical orthogonal polynomials corresponding to the names Krall–Legendre, Krall–Laguerre, and Krall–Jacobi is done. Global asymptotic properties of the zeros of these polynomials are also obtained. | 2022-09-13T17:07:49.879Z |
141,254,619 | {
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} | music education historical contexts and perspectives What to say and what to do when mostly your friends love reading? Are you the one that don't have such hobby? So, it's important for you to start having that hobby. You know, reading is not the force. We're sure that reading will lead you to join in better concept of life. Reading will be a positive activity to do every time. And do you know our friends become fans of music education historical contexts and perspectives as the best book to read? Yeah, it's neither an obligation nor order. It is the referred book that will not make you feel disappointed. | 2022-09-14T19:29:52.144Z |
235,296,263 | {
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"url": "https://www.mdpi.com/1999-4923/13/6/776/pdf?version=1622455307"
} | DN203368 ((E)-3-[1-(4-[4-isopropylpiperazine-1-yl]phenyl) 3-methyl-2-phenylbut-1-en-1-yl] phenol) is a 4-hydroxy tamoxifen analog that is a dual inverse agonist of estrogen-related receptor β/γ (ERRβ/γ). ERRγ is an orphan nuclear receptor that plays an important role in development and homeostasis and holds potential as a novel therapeutic target in metabolic diseases such as diabetes mellitus, obesity, and cancer. ERRβ is also one of the orphan nuclear receptors critical for many biological processes, such as development. We investigated the in vitro metabolism of DN203368 by conventional and metabolomic approaches using high-resolution mass spectrometry. The compound (100 μM) was incubated with rat and human liver microsomes in the presence of NADPH. In the metabolomic approach, the m/z value and retention time information obtained from the sample and heat-inactivated control group were statistically evaluated using principal component analysis and orthogonal partial least-squares discriminant analysis. Significant features responsible for group separation were then identified using tandem mass spectra. Seven metabolites of DN203368 were identified in rat liver microsomes and the metabolic pathways include hydroxylation (M1-3), N-oxidation (M4), N-deisopropylation (M5), N,N-dealkylation (M6), and oxidation and dehydrogenation (M7). Only five metabolites (M2, M3, and M5-M7) were detected in human liver microsomes. In the conventional approach using extracted ion monitoring for values of mass increase or decrease by known metabolic reactions, only five metabolites (M1-M5) were found in rat liver microsomes, whereas three metabolites (M2, M3, and M5) were found in human liver microsomes. This study revealed that nontargeted metabolomics combined with high-resolution mass spectrometry and multivariate analysis could be a more efficient tool for drug metabolite identification than the conventional approach. These results might also be useful for understanding the pharmacokinetics and metabolism of DN203368 in animals and humans. | 2022-10-21T00:42:56.013Z |
254,325,443 | {
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"url": "https://recima21.com.br/index.php/recima21/article/download/2411/1734"
} | O presente trabalho tem por objetivo realizar um estudo sobre o concreto para a construção de fundações, observando a possibilidade de uso de alguns métodos de dosagem, conceituados nesta pesquisa; além de conceituar concreto e fundação; identificar qual dosagem correta de concreto para que a fundação seja segura e durável; conhecer as normas regulamentadoras como a NBR 6118 e 6122, que definem qual a dosagem de concreto ideal para que se resulte numa fundação de qualidade e segura. Para realizar este trabalho, foi realizada uma pesquisa bibliográfica, por meio de artigos acadêmicos, sites, normas regulamentadoras e livros. Por meio da pesquisa, foi possível entender como é relevante definir a dosagem de concreto para a construção da fundação de uma edificação, pois, se a dosagem for incorreta, a edificação, além de não se tornar segura, pode apresentar manifestações patológicas que reduzem sua durabilidade. Com isso, compreende-se que analisar a dosagem de concreto, no processo de construção de uma edificação, é importante, principalmente na etapa de construção das fundações, pois estas são responsáveis pela estrutura da edificação, tornando-a mais segura e durável. | 2022-12-10T09:09:26.004Z |
120,347,608 | {
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} | This paper describes a simple, low cost technique for producing a micro-oxygen sensor based on indicator chemistry, and results obtained using this device to monitor dissolved oxygen concentration are reported. The technology is based on the use of submicron optical fiber tips which have a fluorescent chemical reagent immobilized on their tip surface. Fiber tips were formed by drawing single-mode optical fiber in a fusion splicer. Sol-gel films doped with a fluorescent, oxygen sensitive chemical indicator were then deposited on the surface of the fiber tip using dip-coating techniques. The sensors that we have developed using these coating technologies are reversible and have response times of a few tenths of a second. | 2022-12-17T21:55:06.485Z |
617,817 | {
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} | In order to early diagnosis and treatment of knee abnormalities, in this study an automated diagnosis system using wearable EMG and goniometer sensors is proposed. Eight different classification techniques are investigated with a set of time-domain features. The experiments are conducted with 22 subjects' data and the best accuracy of 97.17% is achieved based on the Bagged Decision Trees classifier. We have also evaluated the classifications quality with Fixed-size Overlapping Sliding Window (FOSW) segmentation technique where SVM and Bagged Decision Trees classifiers could obtain the accuracy of 100% in distinguishing healthy subjects from people with knee abnormality. | 2022-12-21T02:31:16.031Z |
123,438,978 | {
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} | The effect of the Quasi-Biennial Oscillation (QBO) and the El Nino Southern Oscillation (ENSO) on the 11-year solar cycle modulation of the winter-mean North Atlantic Oscillation (NAO) is examined through analysis of observational data from 1958 to 2000. It is found that the solar cycle modulation of the NAO is more strongly enhanced in the westerly phase of the 50-hPa QBO wind and the cold phase of ENSO, although separation of these effects is statistically difficult. On these phases, the signal of the winter-mean NAO extends more to the upper stratosphere and summer-AO reappears more strongly in high solar years, whereas the signal is weaker throughout in low solar years. | 2022-12-29T14:45:23.004Z |
109,071,410 | {
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} | We describe an experimental investigation of the waveforms of free and forced oscillations of electrical and mechanical systems. Computer control of data-taking facilitates accurate measurements and the study of transients when the sine wave is switched on. | 2022-02-10T06:39:41.537Z |
248,400,227 | {
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} | Soil pollution by the contaminants of emerging concern (CECs) or emerging contaminants deserves attention worldwide because of their toxic health effects and the need for developing regulatory guidelines. Though the global soil burden by certain CECs is in several metric tons, the source-tracking of these contaminants in soil environments is difficult due to heterogeneity of the medium and complexities associated with the interactive mechanisms. Most CECs have higher affinities towards solid matrices for adsorption. The CECs alter not only soil functionalities but also those of plants and animals. Their toxicities are at nmol to μmol levels in cell cultures and test animals. These contaminants have a higher propensity in accumulating mostly in root-based food crops, threatening human health. Poor understanding on the fate of certain CECs in anaerobic environments and their transfer pathways in the food web limits the development of effective bioremediation strategies and restoration of the contaminated soils and endorsement of global regulatory efforts. Despite their proven toxicities to the biotic components, there are no environmental laws or guidelines for certain CECs. Moreover, the information available on the impact of soil pollution with CECs on human health is fragmentary. Therefore, we provide here a comprehensive account on five significantly important CECs, viz., (i) PFAS, (ii) micro/nanoplastics, (iii) additives (biphenyls, phthalates), (iv) novel flame retardants, and (v) nanoparticles. The emphasis is on (a) degree of soil burden of CECs and the consequences, (b) endocrine disruption and immunotoxicity, (c) genotoxicity and carcinogenicity, and (d) soil health guidelines. | 2022-11-18T18:03:44.134Z |
102,493,619 | {
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} | An algorithm for minimizing roundoff noise in extended state-space (e-state) realizations of recursive digital filters, where the order of the e-state equation is 2, is developed. It is shown that previous efforts to minimize roundoff noise in e-state structures have not provided a global minimum. The algorithm presented applies an unconstrained transformation matrix to an arbitrary starting state-space structure to produce an intermediate structure. A second matrix transforms the intermediate structure to e-state form. A conjugate-gradient optimization scheme is used to determine the coefficients of the first matrix that minimize the roundoff noise gain of the e-state structure produced by the second transformation. A numerical example illustrates that orders-of-magnitude improvement over previous results can be achieved with this approach.<<ETX>> | 2022-12-21T02:02:16.417Z |
171,727,431 | {
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} | Ce numero des Cahiers Robinson reunit un ensemble d’articles sur les relations entre la Bible (l’Ancien et le Nouveau Testament) et la litterature de jeunesse. L’etude des rapports entre la litterature et les Ecritures ne date pas d’aujourd’hui — en Europe la Bible irrigue depuis toujours la litterature, pour laquelle elle represente un hypotexte fondamental, ou, comme l’affirmait Northrop Frye, le Grand Code — et elle s’est doublee de l’etude des mythes et des figures bibliques et leurs meta... | 2022-01-27T18:27:26.565Z |
238,853,243 | {
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} | <jats:p>In this paper, we consider a nonhomogeneous differential operator equation of first order <jats:inline-formula>
<math xmlns="http://www.w3.org/1998/Math/MathML" id="M1">
<msup>
<mrow>
<mi>u</mi>
</mrow>
<mrow>
<mo>′</mo>
</mrow>
</msup>
<mfenced open="(" close=")" separators="|">
<mrow>
<mi>t</mi>
</mrow>
</mfenced>
<mo>+</mo>
<mi>A</mi>
<mi>u</mi>
<mfenced open="(" close=")" separators="|">
<mrow>
<mi>t</mi>
</mrow>
</mfenced>
<mo>=</mo>
<mi>f</mi>
<mfenced open="(" close=")" separators="|">
<mrow>
<mi>t</mi>
</mrow>
</mfenced>
</math>
</jats:inline-formula>. The coefficient operator <jats:inline-formula>
<math xmlns="http://www.w3.org/1998/Math/MathML" id="M2">
<mi>A</mi>
</math>
</jats:inline-formula> is linear unbounded and self-adjoint in a Hilbert space. We assume that the operator does not have a fixed sign. We associate to this equation the initial or final conditions <jats:inline-formula>
<math xmlns="http://www.w3.org/1998/Math/MathML" id="M3">
<mi>u</mi>
<mfenced open="(" close=")" separators="|">
<mrow>
<mn>0</mn>
</mrow>
</mfenced>
<mo>=</mo>
<mi mathvariant="normal">Φ</mi>
<mtext> or </mtext>
<mi>u</mi>
<mfenced open="(" close=")" separators="|">
<mrow>
<mi>T</mi>
</mrow>
</mfenced>
<mo>=</mo>
<mi mathvariant="normal">Φ</mi>
</math>
</jats:inline-formula>. We note that the Cauchy problem is severely ill-posed in the sense that the solution if it exists does not depend continuously on the given data. Using a quasi-boundary value method, we obtain an approximate nonlocal problem depending on a small parameter. We show that regularized problem is well-posed and has a strongly solution. Finally, some convergence results are provided.</jats:p> | 2022-06-03T22:03:17.867Z |
84,454,782 | {
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} | The literature suggests that chemical communication by primer and releaser pheromones may be extensive within the helminths. Although our detailed knowledge of these events is sparse, the number of reports indicates that a chemical mediation of developmental, reproductive, and behavioral processes may be mandatory in trematodes, turbellarians, and cestodes. Accordingly, this review presents a summary of our current status. | 2022-09-14T14:05:14.150Z |
252,325,748 | {
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"url": "https://tapchinghiencuuyhoc.vn/index.php/tcncyh/article/download/1003/692"
} | Nghiên cứu nhằm mô tả thực trạng sử dụng truyền thông mạng xã hội (MXH) của người bệnh trong chăm sóc sức khoẻ răng miệng ở một số cơ sở khám chữa bệnh tại Hà Nội năm 2021 - 2022. Nghiên cứu mô tả cắt ngang trên 474 người bệnh đã từng sử dụng dịch vụ chăm sóc răng miệng tại Hà Nội trong thời gian từ tháng 05/2021 đến tháng 03/2022. Kết quả cho thấy tất cả người bệnh đều có tài khoản mạng xã hội, trong đó nền tảng phổ biến để tìm kiếm dịch vụ nha khoa là Facebook (79,9%), Zalo 8,2%. Các dịch vụ nha khoa thường tìm kiếm qua mạng xã hội chiếm tỉ lệ cao là niềng răng 40,7%; lấy cao răng, hàn răng sâu 29,1%; chữa răng 24,5%. Một số yếu tố chính liên quan đến việc lựa chọn nha sĩ hay phòng khám qua mạng xã hội là trình độ của nha sĩ (53,6%); các đánh giá tích cực (45,6%); hình ảnh trước và sau điều trị 44,7%; cơ sở vật chất trang thiết bị 32,9%; giới thiệu từ bạn bè/người thân 29,3%. Kết quả nghiên cứu đã góp phần làm sáng tỏ hơn vai trò của các nền tảng xã hội trong mối quan hệ và tương tác giữa người bệnh và bác sỹ răng hàm mặt. | 2022-10-21T00:41:53.476Z |
246,865,839 | {
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} | 1 Department of Urology, La Croix du Sud Clinic, 52 chemin de Ribaute, 31130, Quint Fonsegrives, France; 2 Unit of Functional Explorations, Tenon Hospital, Pierre and Marie Curie University, Paris, France; 3 Department of Urology, Hospital, Angoulême, France; 4 Department of Urology, La Croix du Sud Clinic, 52 chemin de Ribaute, 31130, Quint Fonsegrives, France; 5 Department of Urology, Tenon Hospital, Pierre and Marie Curie University, Paris, France; 6 Department of Urology, Saint-Louis Hospital, Denis Diderot University, Paris, France. | 2022-12-05T14:53:07.351Z |
14,619,632 | {
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} | In this paper, a new approach in the theory of nonlinear ill-posed problems is applied to the statement of one-dimensional inverse scattering problems. The first problem is the problem of reflectometry subsurface analysis of one-dimensional permittivity inhomogeneities. The second is the problem of the synthesis of multilayer dielectric structures with a desired reflection spectrum. | 2022-12-15T19:54:05.380Z |
4,537,997 | {
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} | Attention-deficit hyperactivity disorder (ADHD) is a common neuropsychiatric disorder that is often diagnosed during childhood, but has also increasingly been recognized to occur in adults. Importantly, up to 52% of children (including adolescents) and 87% of adults with ADHD also have a comorbid psychiatric disorder. The presence of a comorbid disorder has the potential to impact diagnosis and could affect treatment outcomes. Atomoxetine is a nonstimulant treatment for ADHD. Despite numerous published studies regarding efficacy of atomoxetine in the treatment of ADHD in patients with comorbid disorders, there is limited information about the impact of individual common comorbid disorders on the efficacy of atomoxetine for ADHD, especially with regard to adults. Moreover, a cumulative review and assessment of these studies has not been conducted. For this reason, we performed a literature review to find, identify, and cumulatively review clinical studies that examined the efficacy of atomoxetine in the treatment of patients with ADHD and comorbid psychiatric disorders. We found a total of 50 clinical studies (37 in children; 13 in adults) that examined the efficacy of atomoxetine in patients with ADHD and a comorbid disorder. The comorbidities that were studied in children or in adults included anxiety, depression, and substance use disorder. Overall, the presence of comorbidity did not adversely impact the efficacy of atomoxetine in treatment of ADHD symptoms in both patient populations. In the studies identified and assessed in this review, atomoxetine did not appear to exacerbate any of the comorbid conditions and could, therefore, be an important therapy choice for the treatment of ADHD in the presence of comorbid disorders. | 2022-12-20T00:30:18.478Z |
11,412,642 | {
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} | The fault-tolerance control in scale-free wireless sensor networks against cascading failure is analysed in this paper. Based on the node load redistribution and constant capacity of the scale-free wireless sensor networks, a new load distribution model is proposed under a single random node failure. By the probability generating function method, the relationships between the load and the largest connected component after cascading failures is given. The influence of the single random node failure load distribution parameters and topological parameters on the size of the cascading failure is analysed, and then the critical load value of the cascading failure in the power law load distribution is obtained. The scale of cascading failure is proportional to the degree distribution coefficient and power exponent, and it can be controlled by the critical load value. Once the network load parameter is beyond the critical load value, a random node failure will cause the whole network cascading failure. In this paper, the load redistribution rule is proposed, which can enhance the cascading failure critical load value fault-tolerance accuracy. Meanwhile, the degree distribution and the exponential correlation parameters can effectively compensate for the influence of the cascading failure and enhance the fault-tolerant ability in scale-free wireless sensor networks. | 2022-12-19T05:34:47.049Z |
46,357,753 | {
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} | Predictions of glucose concentrations throughout the physiological range are obtained in vitro using partial least squares regression analysis of mid-infrared transmission spectra. Concentrations as low as 30 mg/dL are predicted to clinical accuracy. | 2022-02-11T23:46:12.601Z |
125,453,477 | {
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} | AbstractMonte Carlo calculations are performed for a full-coverage spherical system consisting of a stainless steel first wall and a lead-beryllium neutron multiplier. All the calculations use the MORSE-CG code, employing the Los Alamos National Laboratory 30-group neutron cross-section set CLAW-IV in P3 approximation. For multiplier thicknesses varying from 3 to 22.5 cm, the ratio of neutrons leaking from the system with and without 1.5-cm-thick stainless steel decreases from 1.48 to 1.41 for lead and from 1.78 to 1.58 for beryllium. For a three-region system consisting of a first wall, multiplier, and a homogeneous mixture of water and natural lithium, the tritium breeding ratio for the stainless steel-beryllium-homogeneous (natural lithium + water) system is only ∼9% more than that of the stainless steel-lead-homogeneous (natural lithium + water) system. Recent measurements and calculations on neutron multiplication suggest a downward correction for Be(n,2n) and an upward correction for Pb(n,2n) in the... | 2022-07-27T02:10:21.638Z |
12,901,983 | {
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} | Can taxation provide a partial solution to malnutrition? Simon Nicholas Williams from the Feinberg School of Medicine, Northwestern University, considers the potential of ‘soda taxes’ and ‘fat taxes’ as public health policies, in both low and high income countries. | 2022-09-07T04:38:32.557Z |
31,944,108 | {
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} | Abstract Myringotomy is one of the most common procedures performed by ENT surgeons. Use of the tip of a hypodermic needle not only provides a neat and precise incision into the tympanic membrane, but is also a cheap and disposable means of doing so. Sterility is virtually guaranteed avoiding any possibility of cross contamination between consecutive patients. | 2022-09-10T17:57:24.037Z |
153,442,527 | {
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} | Abstract By Danish standards there exists an extensive literature on the agrarian reforms of the latter half of the eighteenth century, but this has shown only limited concern for the attitudes and reactions of the peasantry to reforms in agriculture and changes in the rural community. The patriotic and liberal historical writers of the 1840s regarded the agrarian reforms as a recent decisive turning point, which liberated the peasants from centuries of oppression and permitted their free and independent participation in the evolution of society during the nineteenth century. Later scholars stimulated by the centenary (in 1888) of the abolition of the stavnsband (adscription), accepted the same general view. All this and later work focused largely upon the motives underlying the reform legislation, the conflicts between the leading groups, mainly government, officials and landowners, and upon the wide-ranging debate on the reform in pamphlets and newspapers. Fridlev Skrubbeltrang's Husmand og Indersle (Co... | 2022-09-14T13:32:26.641Z |
124,033,970 | {
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} | In recent years the harmonic analysis of n-fold (n > 2) metaplectic coverings of GL 2 has played an increasingly important role in certain aspects of algebraic number theory. In large part this has been inspired by the pioneering work of Kubota (see [3] for example); as an application one could cite the solution by Heath-Brown and Patterson [3] to a question of Kummer's on the distribution of the arguments of cubic Gauss sums. In that paper, Eisenstein series on the 3-fold metaplectic cover of GL 2(A) play a crucial role. The object of this note is to point out that the theory of Eisenstein series can be made to work for a wide class of finite central coverings. Indeed, once the assumptions are made, the usual theory carries over readily, and one obtains a spectral decomposition of the appropriate L 2-space of functions; this is done in Section 2 of this paper. | 2022-12-15T15:14:50.374Z |
33,838,622 | {
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"url": "https://europepmc.org/articles/pmc4151980?pdf=render"
} | Wildlife consumption can be viewed as an ecosystem provisioning service (the production of a material good through ecological functioning) because of wildlife's ability to persist under sustainable levels of harvest. We used the case of wildlife harvest and consumption in northeastern Madagascar to identify the distribution of these services to local households and communities to further our understanding of local reliance on natural resources. We inferred these benefits from demand curves built with data on wildlife sales transactions. On average, the value of wildlife provisioning represented 57% of annual household cash income in local communities from the Makira Natural Park and Masoala National Park, and harvested areas produced an economic return of U.S.$0.42 ha−1· year−1. Variability in value of harvested wildlife was high among communities and households with an approximate 2 orders of magnitude difference in the proportional value of wildlife to household income. The imputed price of harvested wildlife and its consumption were strongly associated (p< 0.001), and increases in price led to reduced harvest for consumption. Heightened monitoring and enforcement of hunting could increase the costs of harvesting and thus elevate the price and reduce consumption of wildlife. Increased enforcement would therefore be beneficial to biodiversity conservation but could limit local people's food supply. Specifically, our results provide an estimate of the cost of offsetting economic losses to local populations from the enforcement of conservation policies. By explicitly estimating the welfare effects of consumed wildlife, our results may inform targeted interventions by public health and development specialists as they allocate sparse funds to support regions, households, or individuals most vulnerable to changes in access to wildlife. | 2022-12-23T02:18:48.242Z |
84,566,307 | {
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} | The results indicate that controlled environment evaluations of cultivar resistance to verticillium wilt of alfalfa were in agreement with the cultivars' reaction in the field following natural infection and that verticillium wilt causes substantial yield reduction in susceptible cultivars. It is estimated that alfalfa cultivars should possess levels of resistance comparable to that of the check cultivar Vertus to avoid yield losses due to verticillium wilt | 2022-01-27T15:28:35.287Z |
238,057,776 | {
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} | Detection of coronavirus disease 2019 (COVID-19) in early stage is indispensible for outcome improvement and interruption of transmission chain. Clear understanding of the nature of the diagnostic tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and their challenges, collecting the most diagnostically valuable specimen at the right time from the right anatomic site, and interpretation of their findings is important. This review scrutinizes current challenges and interpretation of reverse transcriptase polymerase chain reaction (RT-PCR), as the reference method, loop-mediated isothermal amplification (LAMP), antibody and antigen detection, typical lung imaging characteristics and prominent abnormal changes in laboratory findings of patients with proven COVID-19, and describes how the results may vary over time. Bronchoalveolar lavage fluid and sputum specimens demonstrate the highest positive rates (93% and 72%, respectively) in molecular diagnosis of COVID-19. Alternatively, repeated RT-PCR assays can be performed;as over time, it is an increase in the likelihood of the SARS-CoV-2 being present in the nasopharynx. Combining clinical evidence with results of chest computed tomography (CT) and RT-PCR can minimize the risk of diagnostic errors. Elevated levels of interleukin 6 (IL-6) and D-dimer are thought to be closely associated with the occurrence of severe COVID-19 in adults, and their combined detection can serve as early factors predicting the severity of COVID-19. Moreover, elevated acute phase proteins are associated with a poor outcome in COVID-19. Serological diagnosis also is an important tool to understand the extent of COVID-19 in the community, and to identify individuals, who are immune. Antibodies begin to increase from the second week of symptom onset. | 2022-02-07T20:38:15.779Z |
159,682,689 | {
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"url": "https://journals.openedition.org/etudesrurales/pdf/48"
} | Cet ouvrage est la publication des actes de rencontres qui se sont tenues a Riom en novembre 1996, organisees par la Federation des associations de musiques et danses traditionnelles (FAMDT) et l'Agence des musiques traditionnelles en Auvergne (AMTA), sous la coordination de Jose Dubreuil. L'objectif est de faire emerger toute la complexite des musiques populaires et de montrer quelles representations elles ont engendrees au cours de ce siecle. Le livre comporte quatre chapitres. Le pr... | 2022-05-29T22:38:41.727Z |
135,951,943 | {
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} | Civil and industrial buildings and structures have lately become more frequently exposed to dynamic impacts caused by emergencies. Such loads are random in nature and are characterized by high intensity and short duration of action. In this regard, protection of structures from these impacts comprises an important scientific and practical problem. One of the ways of possible improvement of structural resistance to dynamic loads of great intensity is the use of yielding supports. This article presents the results of research of reinforced concrete slabs placed on yielding supports. Yielding supports are presented in the form of deformable elements of ring cross-section, which are characterized by three phases of deformation: elastic, elastoplastic, and elastoplastic with hardening. The present research considers behavior of the slab in elastic phase, while behavior of supports is analyzed in elastoplastic and elastoplastic with hardening phases. Conducted studies allowed evaluating the influence of rigidit... | 2022-07-31T12:59:45.262Z |
151,612,910 | {
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"DOI": "10.21902/2525-9857/2016.V2I2.1240",
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} | In the globalized world, the demands of the consumer society influence working conditions. Taylorism, Fordism and Toyotism show the linkage of labor reality to productive flexibility. The precariousness of labor was exposed through the examination of the peculiarities of outsourcing, especially regarding fundamental rights and the environment of work. Finally, the legal feasibility of the subcontracting of the final activities of the enterprises was examined, whose release is object of a legislative proposal that intends to regulate the outsourcing institute in Brazil. Bibliographical and documentary research was used as methodology, having as parameters books, scientific articles and normative texts. | 2022-12-15T10:36:30.420Z |
206,652,011 | {
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} | Sugar rush Flying requires high levels of energy production, which causes muscular oxidative damage. Food-derived antioxidants can protect against such damage; however, nectar is devoid of these compounds. Levin et al. found that nectar-feeding hawkmoths fed high concentrations of sugar had lower levels of damage than unfed moths. Sugar-fed moths generated antioxidant compounds by shunting glucose through a pentose phosphate pathway. This mechanism may have allowed for the evolution of energy-intensive flying nectarivores. Science, this issue p. 733 Nectar-derived sugars protect nectar-eating insects from flight muscle oxidative damage. Nectar-feeding animals have among the highest recorded metabolic rates. High aerobic performance is linked to oxidative damage in muscles. Antioxidants in nectar are scarce to nonexistent. We propose that nectarivores use nectar sugar to mitigate the oxidative damage caused by the muscular demands of flight. We found that sugar-fed moths had lower oxidative damage to their flight muscle membranes than unfed moths. Using respirometry coupled with δ13C analyses, we showed that moths generate antioxidant potential by shunting nectar glucose to the pentose phosphate pathway (PPP), resulting in a reduction in oxidative damage to the flight muscles. We suggest that nectar feeding, the use of PPP, and intense exercise are causally linked and have allowed the evolution of powerful fliers that feed on nectar. | 2022-12-21T01:31:38.510Z |
18,911,479 | {
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"DOI": "10.1021/ac5007798",
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} | During the deep reactive ion etching process, the sidewalls of a silicon mold feature rough wavy structures, which can be transferred onto a polydimethylsiloxane (PDMS) microchannel through the soft lithography technique. In this article, we utilized the wavy structures of PDMS microchannel sidewalls to initiate and cavitate bubbles in the presence of acoustic waves. Through bubble cavitation, this acoustofluidic approach demonstrates fast, effective mixing in microfluidics. We characterized its performance by using viscous fluids such as poly(ethylene glycol) (PEG). When two PEG solutions with a resultant viscosity 54.9 times higher than that of water were used, the mixing efficiency was found to be 0.92, indicating excellent, homogeneous mixing. The acoustofluidic micromixer presented here has the advantages of simple fabrication, easy integration, and capability to mix high-viscosity fluids (Reynolds number: ∼0.01) in less than 100 ms. | 2022-12-19T18:10:52.848Z |
219,798,164 | {
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} | Objective
To analyze the correlation between clinical phenotypes and genotypes in 6 children with primary distal renal tubular acidosis (dRTA).
Methods
The clinical data of 6 children confirmed as dRTA in Wuhan Children′s Hospital, Tongji Medical College, Huazhong University of Science & Technology from November 2017 to August 2019 were collected, and related auxiliary examination was performed to assess their growth and development.The venous whole blood was reserved for Trio whole exome sequencing, and full spectrum genetic disease accurate diagnosis cloud platform was applied to systematic data screening and analysis.The suspected mutations were checked by Sanger sequencing, and then the role of protein was predicted by software.
Results
Clinical manifestations, signs and auxiliary examination results of the 6 children accorded with the diagnostic criteria of dRTA, and the prominent characteristics was growth retardation.One case had knee valgus, one had osteoporosis, and the auxiliary examination results showed that both of them had alkaline urine, metabolic acidosis, and hypokalemia.Three children had nephrocalcinosis, and 2 children had nephrolithiasis.The parents of the 6 patients were all normal without phenotypes.Mutations in the SLC4A1 gene were identified in 4 patients, including 1 child with a reported homozygous autosomal recessive missense mutation(c.2102G>A, p.G701D), who had dRTA and hemolytic anemia, and 3 children with the reported de novo heterozygous autosomal dominant missense mutation(c.1766G>A, p.R589H, c.1765C>T, p.R589C), whose age at diagnosis was related to abnormal renal imaging.Compound heterozygous autosomal recessive mutations in the ATPV1B1 gene were identified in 1 patient, and they were novel heterozygous missense mutations (1153C>A, p.P385T and c. 806C>T, p.P269L). A novel homozygous autosomal recessive missense mutation was identified in 1 patient in the ATPV0A4 gene(c.1899C>A, p.Y633X, 208).
Conclusions
Mutations in SLC4A1, ATP6V1B1, ATP6V0A4 genes are identified as the main causes of the primary dRTA, and the phenotypes was related to the mutation features and genotypes.Genetic test should be conducted on patients suspected as dRTA for early molecular diagnosis, thereby improving clinical phenotypic screening and individualized treatment.
Key words:
Distal renal tubular acidosis; Genetic mutation; SLC4A1 gene; ATP6V1B1 gene; ATP6V0A4 gene | 2022-01-27T04:59:05.831Z |
170,134,305 | {
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"url": "http://revistas.uned.es/index.php/rif/article/download/5563/5307"
} | La obra de Merleau-Ponty ha sido conocida, principalmente, por sus esfuerzos para superar el dualismo antropologico que, en la historia de la filosofia, ha sido sistematizado como cuerpo-alma o espiritu-materia. Sin embargo, la lectura de los escritos posteriores a La estructura del comportamiento y a la Fenomenologia de la percepcion, en especial, la lectura de los Resumenes de curso dictados en el Colegio de Francia durante los anos 1952-1960, de los cuales en los ultimos anos han sido publicadas notas que ofrecen una ampliacion y precision del alcance de la tematica tratada por el autor, nos proporciona elementos para comprender que la preocupacion filosofica de Merleau-Ponty no se restringe solo al plano antropologico, sino que, a traves de esas busquedas, vuelve a plantear uno de los problemas centrales de la filosofia: la relacion entre la conviccion en la creencia en el mundo, esto es, “la fe perceptiva” y la creacion de objetos ideales que constituyen el mundo cultural. Esta problematica responde a la necesidad de mostrar que una de las tareas de la filosofia es comprender que el orden natural y el orden cultural pertenecen al mismo mundo. Lo sensible y lo inteligible no deben ser vistos como ordenes separados: en el paso de lo sensible a lo inteligible “hay doble referencia de mi vida al mundo mudo de la pasividad y al universo voluntariamente retomado por la palabra, la accion y el conocimiento, duplicidad que no es dualismo, puesto que (es) el mismo hombre el que ve y habla [...]”. En un curriculum que presenta ante la Sorbona con el nombre de Titulos y trabajos, el autor reconoce que el hom- | 2022-07-04T22:48:40.771Z |
234,223,859 | {
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"url": "https://doi.org/10.1088/1755-1315/625/1/012003"
} | The paper deals with issues related to the use of the concept of a “smart” city. It is concluded that the “smart” city concept is reviewed in the scientific literature and has practical achievements for large cities. The analysis of features of the Arctic zone of the Russian Federation in the context of innovative development is carried out. The analysis of the process of population distribution in the Arctic zone of the Russian Federation and its result - a network of settlements - is presented. The conclusion is made that the Arctic zone should be the place where, first of all, it is necessary to test the “smart” city concept, and the existing network of settlements and interrelation of various types of settlements in the Arctic zone should be used as the objects of using the technologies of the “smart” city concept and their applications. The technologies of the “smart” city concept, which can be used for different types of settlements in the Arctic zone, are determined. The methodological approach taken as the basis for this paper includes: a) an analytical review of literature, focused on the geographical, technological, and institutional characteristics and abilities to implement the concept of sustainable development of the AZRF on the basis of using information and communication technologies (ICT), robotics, and intelligent solutions in the projects of the “smart” city; b) conceptual construction of the real-world virtual cyberspace of the AZRF, or a complex of “socio-cyber-physical systems and intellectual space”, which could serve not only for the purposes of monitoring of the mentioned area but in the future could also become a flexible and multi-faceted tool for managing sustainable development of the AZRF. Keywords: Arctic zone of the Russian Federation, development drivers, real-virtual cyberspace, sustainable development, unmanned aerial vehicles. | 2022-10-05T13:30:59.308Z |
52,147,611 | {
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"DOI": "10.1109/ReCoSoC.2018.8449378",
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} | A heterogeneous architecture combines, within the same hardware, different kinds of processors, with the goal of delivering fast execution at lower energy budgets. Because energy is such an important parameter of the efficiency of these architectures, much effort has been put into the implementation of techniques to measure the power dissipated by programs that they run. Yet, a vast majority of publications reporting experimental results produced on heterogeneous architectures either resort to simulations or rely on hardware counters; physical measurements are rare. In this paper, we introduce an apparatus - hardware and software - that we have been using to measure energy consumption in Odroid-based big.LITTLE architectures running the Android execution environment. This infra-structure is affordable and reliable. To demonstrate its viability, we show how we can use it to build oracles, i.e., a map that assigns different parts of a program to the hardware configuration that minimizes its energy consumption. | 2022-11-15T07:30:24.194Z |
187,676,537 | {
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"DOI": "10.1115/GT2007-27579",
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} | Here we report on the application of non-axisymmetric endwall contouring to mitigate the endwall losses of one conventional- and two high-lift low-pressure turbine airfoil designs. The design methodology presented combines a gradient-based optimization algorithm with a three-dimensional CFD flow solver to systematically vary a free-form parameterization of the endwall. The ability of the CFD solver employed in this work to predict endwall loss modifications resulting from non-axisymmetric contouring is demonstrated with previously published data. Based on the validated trend accuracy of the solver for predicting the effects of endwall contouring, the magnitude of predicted viscous losses forms the objective function for the endwall design methodology. This system has subsequently been employed to optimize contours for the conventional-lift Pack B and high-lift Pack D-F and Pack D-A low-pressure turbine airfoil designs. Comparisons between the predicted and measured loss benefits associated with the contouring for Pack D-F design are shown to be in reasonable agreement. Additionally, the predictions and data demonstrate that the Pack D-F endwall contour is effective at reducing losses primarily associated with the passage vortex. However, some deficiencies in predictive capabilities demonstrate here highlight the need for a better understanding of the physics of endwall loss-generation and improved predictive capabilities. More detailed analysis of the contouring results for the Pack B design is presented in a companion paper (Knesevici et al. [1]).Copyright © 2007 by ASME | 2022-12-14T04:17:06.555Z |
84,643,659 | {
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"DOI": "10.1111/J.1439-0523.2007.01467.X",
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} | The crop cultivars targeted for drought prone areas need to combine drought tolerance and high yield. The present study was conducted to assess the performance of three selected pearl millet landraces, four exotic elite populations and their 12 crosses. They were evaluated for yield, yield components and a drought susceptibility index that was calculated using yield data from drought and non-drought environments. In the non-drought season, the exotic populations had significantly higher grain yield than landraces. However, in the severe drought season, the landraces produced significantly greater biomass, grain and stover yields than elite populations. There was a strong relation between panicle size and ability to produce panicles and delay in flowering under severe stress. The biomass and stover yield of crosses was significantly better than parental populations under both drought stress and near-optimum conditions. The elite populations were most sensitive to drought while crosses were as drought tolerant as landraces because they combined larger panicle size of exotics and lesser delay in flowering of landraces. The results indicated that it is possible to combine drought adaptation with high yield potential through hybridization between adapted landraces and elite genetic materials. | 2022-12-30T06:44:44.427Z |
169,243,535 | {
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} | tion does (the focusing on selected, concrete aspects of the field to the exclusion of the "big picture"). To be sure, this reduces ambiguity in the untrained beginner's mind, but, at the same time, it may substitute a small amount of specific knowledge for the over-all look. This overall look is, in the long run, less dangerous than a little learning. If Moser wished to focus this book on the specific techniques of survey research, then the book would have been strengthened immeasurably by a wider, more sophisticated bibliography. (His bibliography of 296 citations is extensive, but is almost solely concerned with facets of sampling and questionnaire construction.) A broader suggested bibliography might be helpful to students in terms of indicating the content of research. Such a reading list might include some basic social science textbooks as An Introduction to Projective Techniques (Anderson and Anderson, 1951); The Language of Social Research (Paul F. Lazarfeld and Morris Rosenberg, editors, 1955); Theory and Problems of Social Psychology (David Krech and Richard S. Crutchfield, 1948); and Social Psychology (Theodore M. Newcomb, 1950). DONALD L. KANTER Tatham-Laird, Inc. | 2022-02-08T17:56:25.247Z |
143,275,812 | {
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"DOI": "10.1080/03601271003608886",
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} | The aim of the present study was to assess the influence of word image vividness on the immediate and long-term recall (one-day interval) of words using either the rote repetition learning method or the keyword mnemonics method in a sample of adults aged 55 to 70 years. Subjects learned a list of concrete and abstract words using either rote repetition or keyword mnemonics. Individuals using keyword mnemonics recalled more concrete than abstract words both immediately after learning and after a one-day time interval. In contrast, subjects using the repetition method recalled more abstract than concrete words immediately after learning; however, no difference in the number of recalled concrete and abstract words were found after the one-day interval. These findings are discussed in the context of previous studies, and new lines of research are proposed. | 2022-09-06T20:44:34.968Z |
158,835,100 | {
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"DOI": "10.1177/104438948006100502",
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} | By drawing on experiences with women's and men's groups, the use of consciousness raising within many fields of practice is described and encouraged. Issues related to purpose and scope, process and content, and structure in the use of consciousness raising as a skill and a tool for social change are explicated. | 2022-09-14T10:04:41.365Z |
56,169,465 | {
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"DOI": "10.1155/2018/4567213",
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"license": "CCBY",
"status": "GOLD",
"url": "http://downloads.hindawi.com/journals/js/2018/4567213.pdf"
} | Vital signs monitoring is pivotal not only in clinical settings but also in home environments. Remote monitoring devices, systems, and services are emerging as tracking vital signs must be performed on a daily basis. Different types of sensors can be used to monitor breathing patterns and respiratory rate. However, the latter remains the least measured vital sign in several scenarios due to the intrusiveness of most adopted sensors. In this paper, we propose an inexpensive, off-the-shelf, and contactless measuring system for respiration signals taking as region of interest the pit of the neck. The system analyses video recorded by a single RGB camera and extracts the respiratory pattern from intensity variations of reflected light at the level of the collar bones and above the sternum. Breath-by-breath respiratory rate is then estimated from the processed breathing pattern. In addition, the effect of image resolution on monitoring breathing patterns and respiratory rate has been investigated. The proposed system was tested on twelve healthy volunteers (males and females) during quiet breathing at different sensor resolution (i.e., HD 720, PAL, WVGA, VGA, SVGA, and NTSC). Signals collected with the proposed system have been compared against a reference signal in both the frequency domain and time domain. By using the HD 720 resolution, frequency domain analysis showed perfect agreement between average breathing frequency values gathered by the proposed measuring system and reference instrument. An average mean absolute error (MAE) of 0.55 breaths/min was assessed in breath-by-breath monitoring in the time domain, while Bland-Altman showed a bias of −0.03 ± 1.78 breaths/min. Even in the case of lower camera resolution setting (i.e., NTSC), the system demonstrated good performances (MAE of 1.53 breaths/min, bias of −0.06 ± 2.08 breaths/min) for contactless monitoring of both breathing pattern and breath-by-breath respiratory rate over time. | 2022-12-30T18:09:09.748Z |
244,957,372 | {
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"DOI": "10.23919/eecsi53397.2021.9624313",
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} | Autonomous vehicles need sensors to detect the surroundings of the vehicle, especially if there are obstructions that could harm the vehicle or the object itself. The goal is to avoid accidents by detecting as early as possible if there are obstacles. In this study, a series of ultrasonic sensors are used and placed in strategic positions around the vehicle. They are placed in front, in side and in rear of vehicle. When the sensor detects an object, each sensor provides information on the existence of the object in the form of a detection point. These points are still formed as detection points as the results of individual detection from each sensor. In order to integrate all the resulting points, it is necessary to establish a comprehensive detection pattern, to provide information about the safe distance of the vehicle from surrounding objects. The sensors are connected to a programmable microcontroller unit to monitor and control the transmitted signal and sensor detection results. The signal obtained by the microcontroller is fed to the computer unit through the serial port, which is then read using the Data Stream to be displayed on the monitor screen. With this method, the data will be reprocessed to display an integrated detection pattern from all sensors graphically. There are two kinds of graphical pattern formed, spider web pattern and bar pattern. | 2022-09-24T18:49:52.945Z |
247,380,458 | {
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"DOI": "10.3390/metabo12030236",
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},
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"status": "GOLD",
"url": "https://www.mdpi.com/2218-1989/12/3/236/pdf?version=1647582522"
} | Plant roots exude a wide variety of secondary metabolites able to attract and/or control a large diversity of microbial species. In return, among the root microbiota, some bacteria can promote plant development. Among these, Pseudomonas are known to produce a wide diversity of secondary metabolites that could have biological activity on the host plant and other soil microorganisms. We previously showed that wheat can interfere with Pseudomonas secondary metabolism production through its root metabolites. Interestingly, production of Pseudomonas bioactive metabolites, such as phloroglucinol, phenazines, pyrrolnitrin, or acyl homoserine lactones, are modified in the presence of wheat root extracts. A new cross metabolomic approach was then performed to evaluate if wheat metabolic interferences on Pseudomonas secondary metabolites production have consequences on wheat metabolome itself. Two different Pseudomonas strains were conditioned by wheat root extracts from two genotypes, leading to modification of bacterial secondary metabolites production. Bacterial cells were then inoculated on each wheat genotypes. Then, wheat root metabolomes were analyzed by untargeted metabolomic, and metabolites from the Adular genotype were characterized by molecular network. This allows us to evaluate if wheat differently recognizes the bacterial cells that have already been into contact with plants and highlights bioactive metabolites involved in wheat—Pseudomonas interaction. | 2022-12-12T19:53:13.673Z |
44,660,324 | {
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} | Purpose: To measure values for functional reach (FR) and lateral reach (LR) in school children with knee joint hypermobility (KJH), and to examine the correlation of anthropometric measures and KJH with FR and LR values. Methods: A total of 140 children aged 6 to 12 years with typical development (TD) and bilateral KJH of greater than 10° hyperextension participated. Three successive trials of FR and LR tests in standing position with feet shoulder width apart were performed, and the mean of the 3 trials was calculated. Analysis of variance and Bonferroni tests were used to analyze correlation and association of FR and LR values with KJH angle and anthropometric data, respectively, with a 95% confidence interval. Results: In school-aged children with TD, height and KJH contributed significantly to the FR values in both genders, whereas height contributed for LR values among girls alone. Conclusions: Height and KJH affect children's scores on the FR and LR tests of balance. | 2022-12-16T15:53:41.620Z |
40,530,581 | {
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"DOI": "10.1097/ACM.0000000000000486",
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} | Purpose Social judgment research suggests that rater unreliability in performance assessments arises from raters’ differing inferences about the performer and the underlying reasons for the performance observed. These varying social judgments are not entirely idiosyncratic but, rather, tend to partition into a finite number of distinct subgroups, suggesting some “signal” in the “noise” of interrater variability. The authors investigated the proportion of variance in Mini-CEX ratings attributable to such partitions of raters’ social judgments about residents. Method In 2012 and 2013, physicians reviewed video-recorded patient encounters for seven residents, completed a Mini-CEX, and described their social judgments of the residents. Additional participants sorted these descriptions, which were analyzed using latent partition analysis (LPA). The best-fitting set of partitions for each resident served as an independent variable in a one-way ANOVA to determine the proportion of variance explained in Mini-CEX ratings. Results Forty-eight physicians rated at least one resident (34 assessed all seven). The seven sets of social judgments were sorted by 14 participants. Across residents, 2 to 5 partitions (mode: 4) provided a good LPA fit, suggesting that subgroups of raters were making similar social judgments, while different causal explanations for each resident’s performance existed across subgroups. The partitions accounted for 9% to 57% of the variance in Mini-CEX ratings across residents (mean = 32%). Conclusions These findings suggest that multiple “signals” do exist within the “noise” of interrater variability in performance-based assessment. It may be valuable to understand and exploit these multiple signals rather than try to eliminate them. | 2022-12-15T14:21:24.965Z |
9,698,465 | {
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"DOI": "10.1289/EHP.981069",
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} | Quantitative examination of major pathways and routes of exposure to pesticides is essential for determining human risk. The current study was conducted in two apartments and examines the accumulation of the pesticide chlorpyrifos in childrens' toys after the time suggested for reentry after application. It has been established for the first time that a semivolatile pesticide will accumulate on and in toys and other sorbant surfaces in a home via a two-phase physical process that continues for at least 2 weeks postapplication. A summation of the above for a 3-6-year-old child yielded an estimated nondietary total dose of 208 microg/kg/day. Potential exposure from the inhalation pathway was negligible, while dermal and nondietary oral doses from playing with toys contributed to 39 and 61% of the total dose, respectively. If children with high frequency mouthing behavior are considered as candidates for acute exposure to chlorpyrifos residues, the estimated acute dose could be as high as 356 microg/kg/day. Routine reapplication of pesticides could lead to continued accumulation in toys and other sorbant surfaces, e.g., pillows, with large sorbant reservoirs, which can become a long-term source of exposure to a child. Estimates of a child's nondietary exposure to chlorpyrifos associated with toys and other sorbant surfaces for a period of 1 week following application appear to be of public health concern, and studies of actual childhood exposure from this pathway are warranted in the home environment. The above information should be used to determine if current procedures for postapplication reentry are sufficient and to evaluate the need for procedures to store frequently used household toys, pillows, and other sorbant objects during insecticidal application. | 2022-12-20T17:22:04.412Z |
96,718,530 | {
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"DOI": "10.1021/JA00171A030",
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} | In order to gain insight as to the structure(s) of the adduct formed in vivo between human hemoglobin and the anti-diol epoxide (anti-BPDE) of benzo(a)pyrene (BaP), a series of model compounds was synthesized to investigate the effect on the fluorescence line-narrowing (FLN) spectra of heteroatom substitution at C-10 in BaP tetrahydrotetrol analogues. Spectra taken at 4.2 K by vibronic laser excitation at both 356.9 and 363.4 nm revealed marked differences between BaP tetrahydrotetrols and synthetic thioether, amino, and ester adducts of anti-BPDE. Use of these same excitation wavelengths on intact human globin samples obtained from individual s environmentally exposed to ambient levels of BaP yielded vibronic FLN spectra that were virtually indistinguishable from those of a synthetic C-10 carboxylic ester derived from anti-BPDE. | 2022-09-07T02:17:29.590Z |
202,259,257 | {
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} | President Trump is often at odds with the conservative establishment over a range of issues, not least of which is foreign policy. Yet it remains unclear whether supporting “Trumpism” is commensurate with coherent foreign policy views that are distinct from conventionally conservative positions. We evaluate whether the foreign policy views of Trump’s supporters, both in the voting public and among activists, differ from those of other Republicans. We use the 2016 ANES to examine Republican primary voters and the new 2016 State Convention Delegate Study to assess Republican activists. In doing so, we reveal systematic differences in foreign policy preferences between Trump supporters and more establishment conservatives. We demonstrate that the status-threat model need not be confined to domestic politics. Indeed, it may be extended to explain foreign policy preferences on the political right, that of Trump’s supporters in the present case. In doing so, we also find evidence that status threat may well be the source of fracture in the Republican Party. | 2022-12-21T14:43:51.685Z |
168,948,879 | {
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"DOI": "10.26905/JKDP.V19I2.851",
"MAG": "2753454323",
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},
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} | One way to accelerate the growth of Islamic banks in Indonesia was by applying the policy of separation. The purpose of this study was to analyze the relationship between separation policy that had been implemented since 2008 with the operational efficiency of the Islamic banking industry in Indonesia. The method used was regression with dummy variables. The variables used in this study were a dummy variable separation, deposits, financing, assets, NPF, margin deposits of one month, and ROA. The result showed that separation policy had a relationship with the operational efficiency on Islamic banking industry in Indonesia. This result implied that separation policy should have been evaluated because it caused the industry to be less efficient when compared with the condition before the separation. | 2023-01-02T04:52:21.660Z |
154,357,983 | {
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"DOI": "10.5897/AJBM11.1392",
"MAG": "2137327623",
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} | From the perspective of energy efficiency, the paper analyzes the environmental regulations on efficiency of the thermal power industry in China’s 30 provinces in the year of 2004, including the autonomous regions and municipalities. Excluding the environmental effects and the statistical noise, the paper studies the relationship between the level of environmental regulations and the efficiency of China’s thermal power with non-regulations, weak-regulations and strong-regulations. The results demonstrate that environmental regulations can improve the efficiency of China’s thermal power as a whole. However, this theory is not suitable for every region. The study concludes three different developing modes: environmentally- friendly mode influenced by internal forces, weak environmentallyfriendly mode and environmentally-friendly mode created by external forces. The paper suggests three different regulations in correspondence to the three modes. | 2022-02-09T01:52:39.048Z |
118,279,940 | {
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"DOI": "10.1017/S1539299600017871",
"MAG": "1632729720",
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} | The details of the formation of the first objects, stars and galaxies and their subsequent evolution remain a cosmological unknown. Few observational probes of these processes exist. The Cosmic Infrared Background (CIB) originates from this era and measurements of its anisotropy can provide information to test models of both galaxy evolution and the growth of primordial structure. Such measurements should provide a sensitive probe of the large-scale variation in protogalaxy density at redshifts, z ~ 0.5-3, while optical galaxy surveys provide complementary information at z < 0.5 and Lyman alpha absorption forest studies and Cosmic Microwave Background measurements add information at higher redshifts. The Explorer of Diffuse Galactic Emission (EDGE) is a balloon-borne mission designed to measure the spatial fluctuations i'in the CIB from 200 //m to 1 mm on 6' to 3° scales with up to 2/zK sensitivity/resolution element on an Antarctic Long Duration Balloon (LDB) flight. EDGE will employ an array of Frequency Selective Bolometers (Kowitt et al., 1(996) to simultaneously measure spectral and spatial information with seven sky pixels each containing eight spectral bands. EDGE is designed to cover ~100 square degrees of the sky in a single ~10 day LDB flight to create a new observational constraint for large-scale structure formation theories. | 2022-06-13T10:25:52.358Z |
7,946,479 | {
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"DOI": "10.2196/resprot.3192",
"MAG": "2015692272",
"PubMedCentral": "3961749"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.2196/resprot.3192"
} | Background Depression and alcohol misuse represent two of the major causes of disease burden in young adults. These conditions frequently co-occur and this co-occurrence is associated with increased risks and poorer outcomes than either disorder in isolation. Integrated treatments have been shown to be effective, however, there remains a significant gap between those in need of treatment and those receiving it, particularly in young people. The increased availability of Internet-based programs to complement health care presents a unique opportunity in the treatment of these conditions. Objective The objective of our study was to evaluate whether a brief, Internet-based, self-help intervention (the DEAL [DEpression-ALcohol] Project) can be effective in treating co-occurring depression and problematic alcohol use in young people (18-25 years old). Methods The evaluation will take the form of a randomized controlled trial (RCT), comparing the DEAL Project with an attention-control condition (HealthWatch). The RCT will consist of a four-week intervention phase and a 24-week follow-up. It will be entirely Internet-based and open Australia-wide to young people 18 to 25 years old. The primary outcomes will be change in depression symptoms and alcohol use at 5, 12, and 24 weeks post baseline. Secondary outcomes include change in general functioning and quality of life, anxiety/stress symptomatology, and a number of other depression/alcohol related outcomes. Process analysis will also measure engagement across the conditions. Results This study is currently ongoing with preliminary results expected in late 2014. Conclusions This study, to our knowledge, will be the first RCT of a Internet-based treatment for comorbid depression and problematic alcohol use in any age group. If successful, the program represents a novel and innovative approach to addressing the significant harms associated with these conditions and will be an invaluable resource to those not receiving help elsewhere. Trial Registration Australian New Zealand Clinical Trials Registry; ACTRN12613000033741; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363461 (Archived by WebCite at http://www.webcitation.org/6Mrg9VFX4). | 2022-08-20T10:33:53.446Z |
8,955,308 | {
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"DOI": "10.4103/sja.SJA_483_17",
"MAG": "2756984035",
"PubMedCentral": "5637451"
},
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} | An 89‐year‐old female presented with approximately a 30‐year history of progressively worsening dyspnea for the past 30 years and a history of paroxysmal nocturnal dyspnea and orthopnea for 3 days. She was admitted for stabilization and evaluation. There was no history suggestive of rheumatic fever. On examination, she had a heart rate of 120/min, blood pressure of 100/60 mmHg, jugular venous distension (8 cm above the angle of Louis), and pedal edema. The apex was in the 6th left intercostal space, 2 cm outside the midclavicular line. On auscultation, soft S1 and LVS3 were present. A Grade 4/6 pan‐systolic murmur radiating toward the axilla was heard. There was also a pan‐systolic murmur in the left 3rd parasternal region which increased during inspiration. Chest auscultation revealed bilateral basal crepitation. Abdominal examination revealed tender hepatomegaly (liver span: 18 cm). All peripheral pulses were bilaterally and equally palpable. Her family history included some cases of cardiopathy. The electrocardiogram showed sinusal rhythm with rectification of the ST segment in inferior and lateral facies, with a chest X‐ray showing the pulmonary area without any abnormalities and the cardiac area with a calcified area next to the region corresponding to the left cardiac appendage. Doppler echocardiography [Figures 1 and 2] revealed cardiac chambers with normal dimensions, systolic performance of the left ventricle preserved, and the discrete presence of mitral valve reflux. Of significance was the presence of a dilatation because of aneurysm in the posterior area of the left ventricle with an ostial communication between the aneurysm and this cardiac chamber. The flow register through this communication was not obtained because the position of the aneurysm in the mitral subannular plan was clear. In the following hemodynamic study, it was revealed a pressure gradient of 6 mmHg between the right branch and the left branch of the pulmonary artery. The coronary arteriography showed right coronary artery dominance without lesions; a long left anterior descending artery without stenosis; a short‐sized left circumflex coronary artery in the atrioventricular sulcus occluded at the beginning, which received collateral circulation from the right and left coronary arteries; and the angiocardiography showed an increase of the end‐systolic volume of the left ventricle, with diffuse hypokinesis. The mitral valve was competent, and passage of contrast from the mitral subvalvar region to a retrocardiac and calcified aneurysmatic formation could be observed. The aorta and the main pulmonary artery were normal, with a relative stenosis evident in the right A rare case of submitral left ventricular aneurysms Department of Anesthesiology, AIIMS, Patna, Bihar, India | 2022-08-23T23:32:37.522Z |
31,629,462 | {
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"DOI": "10.7205/MILMED-D-14-00567",
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} | PURPOSE
To determine whether the Uniformed Services University (USU) system of workplace performance assessment for students in the internal medicine clerkship at the USU continues to be a sensitive predictor of subsequent poor performance during internship, when compared with assessments in other USU third year clerkships.
METHOD
Utilizing Program Director survey results from 2007 through 2011 and U.S. Medical Licensing Examination (USMLE) Step 3 examination results as the outcomes of interest, we compared performance during internship for students who had less than passing performance in the internal medicine clerkship and required remediation, against students whose performance in the internal medicine clerkship was successful. We further analyzed internship ratings for students who received less than passing grades during the same time period on other third year clerkships such as general surgery, pediatrics, obstetrics and gynecology, family medicine, and psychiatry to evaluate whether poor performance on other individual clerkships were associated with future poor performance at the internship level. Results for this recent cohort of graduates were compared with previously published findings.
RESULTS
The overall survey response rate for this 5 year cohort was 81% (689/853). Students who received a less than passing grade in the internal medicine clerkship and required further remediation were 4.5 times more likely to be given poor ratings in the domain of medical expertise and 18.7 times more likely to demonstrate poor professionalism during internship. Further, students requiring internal medicine remediation were 8.5 times more likely to fail USMLE Step 3. No other individual clerkship showed any statistically significant associations with performance at the intern level. On the other hand, 40% of students who successfully remediated and did graduate were not identified during internship as having poor performance.
CONCLUSIONS
Unsuccessful clinical performance which requires remediation in the third year internal medicine clerkship at Uniformed Services University of the Health Sciences continues to be strongly associated with poor performance at the internship level. No significant associations existed between any of the other clerkships and poor performance during internship and Step 3 failure. The strength of this association with the internal medicine clerkship is most likely because of an increased level of sensitivity in detecting poor performance. | 2022-09-13T06:03:13.271Z |
116,555,203 | {
"externalids": {
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"DOI": "10.3989/GRAELLSIA.2016.V72.160",
"MAG": "2516869964",
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"url": null
} | We obtained the first records of Sciobia (Thilptoblemus) natalia in Europe after a single record from Algeciras (Spain), about one century ago. We found the species in Tarifa, Benelup-Casas Viejas and Alcala de los Gazules (Cadiz province) in plots with open land and herbaceous vegetation of wasteland, cattle states, edges of agricultural land, and hedgerows of pathways and local roads. The species may be common locally, in late spring. It may coexist with Sciobia (Thliptoblemus) caliendrum although the later presents a wider ecological spectrum whereas S. (T.) natalia prefers dense vegetation in more humid soils. Acoustic analyses indicate that the song of both species are very different, making field identification feasible. S. (T.) natalia may however easily go unnoticed among populations of the more conspicuous S. (T.) caliendrum . We discuss possible reasons why this species has gone unnoticed so far and factors that may pose at risk the maintenance of its populations. | 2022-09-16T02:29:51.339Z |
254,272,794 | {
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"DOI": "10.1093/bbb/zbac195",
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} | Thioflavin T, a cationic benzothiazole dye, is typically used to detect the amyloid fibrils. In this study, we analyzed the staining properties of B. subtilis cells using several fluorescent dyes, including Thioflavin T analogues, 2-(4'-Methylaminophenyl) benzothiazole (BTA-1), and 2-(4-aminophenyl) benzothiazole (APBT). Thioflavin T stained vegetative cells in the early log phase and outer layer structures of forespores and mature spores. The inner parts of forespores and heat-killed mature spores were also stained with Thioflavin T. Congo red, auramine O, and rhodamine B stained forespores and mature spores similar to Thioflavin T. In contrast, APBT and BTA-1 fluorescence was detected in the outer layers of vegetative cells, mother cells, forespores, and mature spores, indicating that they bind to the cell membrane and/or cell wall. The combination of the fluorescent dyes used in this study will help analyze morphogenetic processes during sporulation and the damage mechanisms of vegetative cells and spores. | 2022-12-10T03:03:04.579Z |
248,243,677 | {
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"DOI": "10.1145/3514262.3514330",
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} | Supply management plays an important role in the business. In our research, we make the introduction with research background in COVID-19, in the APPLE Inc. and large amount of data is constructed. Several methods are used during the task, for example, literature review, data analysis, quantitative analysis and comparative analysis. The research shows the current problems faced by electronic technology companies, which are instability of the supply chains, material shortage and regional policies, after which the research reasons for deep causes and provides feasible improvements of the company, which are production concentration, purchase limit strategy, online commodity physical models, price reduction, and comprehensive capital. | 2022-12-10T09:06:08.724Z |
109,779,016 | {
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"ArXiv": null,
"DOI": "10.1299/JMTL.2.43",
"MAG": "2000352381",
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} | This study seeks to design a lane keeping controller for motorcycles and to evaluate it by computer simulation with a four-degree-of-freedom model and a rider control model. We applied the optimal control theory to the lane keeping controller as a model-based control. By examining the computer simulation with the rider-in-the-loop system consisting of the motorcycle, the controller, and the rider control model, good lane following performance is achieved without interference between the control input and the rider's input. In addition, the virtual point regulator, which compensates the lateral displacement at the virtual point ahead of the vehicle, corresponds to not only the steering torque disturbance but also the lateral force disturbance by choosing the distance to the virtual point. | 2022-12-17T13:09:31.380Z |
97,381,417 | {
"externalids": {
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"DOI": "10.1111/J.1151-2916.1964.TB13814.X",
"MAG": "2143537833",
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} | The magnetic and dielectric properties of some ilmenite-hematite solid solutions are reported. These properties resemble those of the ferrites. Compositions possessing high electrical resistivities and low dielectric losses were prepared. The introduction of manganese into the system (1 - x)Ni1-vMnvTiO3+ xFe2O3 increases the room temperature magnetic moments and decreases the resistivities. | 2022-03-03T21:58:10.136Z |
165,196,224 | {
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"ArXiv": null,
"DOI": "10.3828/BHS.2018.57",
"MAG": "2896352716",
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} | Este articulo analiza los intercambios y contactos establecidos por diferentes artistas del movimiento de arte concreto con las practicas poeticas experimentales de los anos sesenta en el Estado espanol durante la dictadura franquista. En primer lugar, estudia las redes establecidas entre artistas, criticos de arte y poetas dentro de la peninsula y sus contactos con las redes poeticas internacionales. En segundo, analiza el marco teorico que criticos de arte (Angel Crespo, Pilar Gomez Bedate), poetas (Julio Campal, Ignacio Gomez de Liano) y artistas (Julio Plaza) utilizaron para establecer un territorio estetico comun. Despues, se estudian las estrategias plasticas compartidas entre la pintura y la poesia, mediante el analisis de diferentes obras de Julio Plaza, Jose Maria Iglesias y Elena Asins. Por ultimo, se analizan las relaciones entre arte e ideologia que se proyectaron desde estas practicas, a partir de un programa de corte social, emplazandolas en su contexto ideologico del tardofranquismo. | 2022-09-17T16:02:29.266Z |
154,900,845 | {
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"DOI": "10.1080/00036849500000057",
"MAG": "2067344940",
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} | Ordinary least squares (OLS) regression and data from the March 1990 Current Population Survey are used to estimate yearly earnings averages for white males, white females, black males and black females. In order to test for the possible existence or gender and/or race discrimination, earnings estimates are decomposed, using the tradional Oaxaca (1973) and Blinder (1973) methodology. In comparing these results with those from Carlson and Swartz (1988, using 1979 data), we find that overall and unexplained residual differences have declined quite substantially, but that they still favour white males. We then incorporate an extension of the traditional methodology (Jackson and Lindley, 1989) which allows for testing for the significance of enexplained residuals, and for jointly testing for the significance of residual effect components, the constant and coefficient effects. These results call into question the unambiguous conclusion that earnings differentials uniformly favour white males. Strong support is... | 2022-12-09T16:06:30.987Z |
232,046,204 | {
"externalids": {
"ACL": null,
"ArXiv": "2102.12983",
"DOI": "10.1051/0004-6361/202040145",
"MAG": "3135559607",
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},
"license": null,
"status": "BRONZE",
"url": "https://www.aanda.org/articles/aa/pdf/2021/04/aa40145-20.pdf"
} | eROSITA (extended ROentgen Survey with an Imaging Telescope Array) instrument onboard the Russian-German ‘Spectrum-Roentgen-Gamma’ (SRG) mission observed the Her X-1/HZ Her binary system in multiple scans over the source during the first and second SRG all-sky surveys. Both observations occurred during a low state of the X-ray source when the outer parts of the accretion disk blocked the neutron star from view. The orbital modulation of the X-ray flux was detected during the low states. We argue that the detected X-ray radiation results from scattering of the emission of the central source by three distinct regions: (a) an optically thin hot corona with temperature ~(2−4) × 106 K above the irradiated hemisphere of the optical star; (b) an optically thin hot halo above the accretion disk; and (c) the optically thick cold atmosphere of the optical star. The latter region effectively scatters photons with energies above 5–6 keV. | 2022-10-28T00:24:30.190Z |
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