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245,298,770 | {
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"DOI": "10.1080/08995605.2021.1994329",
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} | ABSTRACT US military Veterans are at greater risk for suicide than those who have never served in the US military. Recent federal calls include the need to investigate military-specific suicide risk and protective factors among military-affiliated populations. To date, no study has examined the link between military identity, self-stigma, and suicide risk. The current study used a nationally representative sample of post-Vietnam US military Veterans (N = 1,461) in order to determine relationships between military identity, self-stigma, and suicide risk. Idealism (OR = 0.86) with less odds of elevated suicide risk, whereas individualism (OR = 1.15) and military self-stigma (OR = 1.39) were associated with increased odds of elevated suicide risk. Military self-stigma was found to mediate the relationship between military identity components and suicide risk. Implications for conceptualization of military Veteran identity, suicide prevention, and future research are discussed. | 2022-12-11T03:19:53.653Z |
155,890,888 | {
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"ArXiv": null,
"DOI": "10.2139/ssrn.2478601",
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} | In the last decade the monetary policy from Romania was deeply changed. The inflation decreased considerably in comparison with the 1990s. From a few years National Bank of Romania adopted the inflation targeting strategy that implied a careful use of the monetary instruments. The success of the Central Bank depends greatly on understanding the monetary transmission mechanism. Using the VAR methodology, we analyze in this article the particularities of the monetary transmission mechanism in Romania. | 2022-02-09T01:05:17.431Z |
49,330,181 | {
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"ArXiv": null,
"DOI": "10.1117/12.528394",
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} | An enhanced version of the fast inter-prediction mode decision and variable block size motion estimation scheme for the H.264 video encoder is proposed in this work. In particular, we focus on the rate estimation model and thresholds for early termination. They are adaptively updated to enhance the coding speed and the rate-distortion performance. More details about the threshold setting and the mode decision processes are also provided. The improved algorithm can achieve a speed-up factor ranging from 70 to 150 times as compared to the full-search algorithm. | 2022-02-11T23:07:58.595Z |
250,859,290 | {
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"DOI": "10.1088/0953-8984/16/23/022",
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} | The effect of Sr chemical pressure on superconductivity was investigated in Hg2(Ba1−ySry)2YCu2O8−δ. The samples were synthesized at high pressure and high temperature from y = 0.0 to full substitution, y = 1.0. These Sr substituted compounds are superconducting, without Ca doping on the Y site, and show a Tc increasing with Sr, reaching 42 K for y = 1.0. A detailed neutron powder diffraction study compares the structural changes induced by this chemical Sr/Ba substitution and the mechanical pressure effects in the Hg-2212 system. It shows the strong decrease of the three Ba/Sr–O distances and consequently the shrinkage of Cu–O 1in−plane and Cu–O 2apical bonds. These structural changes, by affecting the charge transfer which occurs between the charge reservoir and the superconducting block, are responsible of the Tc enhancement with Sr content. | 2022-07-31T09:22:05.428Z |
136,584,864 | {
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"DOI": "10.1557/JMR.2001.0016",
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} | The structure and dielectric properties of Bi 2 O 3 –ZnO–Nb 2 O 5 -based ceramics with pyrochlore–fluorite biphase structure were investigated. Mixed-sintered ceramics were prepared by two precalcined constituents in the system of x [Bi 1.5 Zn 0.5 (Zn 0.5 Nb 1.5 )O 7 ]−(1 − x )Bi 3/4 Nb 1/4 O 7/4 (0.05 ≤ x ≤ 0.35), where Bi 1.5 Zn 0.5 (Zn 0.5 Nb 1.5 )O 7 is a cubic pyrochlore (α) and Bi 3/4 Nb 1/4 O 7/4 is a defect cubic fluorite (F). The phase composition of the mixed-sintered ceramics were characterized as a biphasic structure with a distorted pyrochlore (β) and a fluorite (F) coexisting. The phase ratio of β pyrochlore and F fluorite is related to the chemical composition x. The dielectric properties of the ceramics gradually change with their structure. | 2022-08-21T02:51:39.185Z |
97,276,355 | {
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"DOI": "10.1021/J100464A021",
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} | The master equation is formulated and solved analytically for a ladder-climbing model of the dissociation of a diatomic molecule diluted in a heat bath. The dissociation rate is explicitly related to the normal modes of relaxation of the internal degrees of freedom of the molecule giving, in closed form, an expression for the pseudo-second-order dissociation rate in terms of the energy-level structure and collisional transition probabilities. This form of the rate constant shows clearly the criteria for the occurrence of ''bottleneck'' and ''network'' effects. The dissociation of H/sub 2/ in Ar is studied in detail between 2000 and 6000/sup 0/K. The principal qualitative conclusions in respect of the rate of dissociation are that (a) nonequilibrium effects are significant even at 2000/sup 0/K; (b) rotation enhances the reaction rate, although it is only at very high temperatures (above 6000/sup 0/K) that rotational energy contributes equally with vibrational energy in causing dissociation; (c) the presence of tunneling gives only a very modest enhancement in the rate. The relative contributions to the Arrhenius temperature coefficient of the rate of the following theoretical constructs are delineated. A parallel set of calculations on the dissociation of D/sub 2/ in Ar also gives results in goodmore » agreement with experiment. The principal determinants of the kinetic isotope effect are the differences between H/sub 2/ and D/sub 2/ in the internal relaxation rates and in the energy-level densities. 7 figures, 83 references, 7 tables.« less | 2022-09-07T18:14:59.195Z |
225,100,337 | {
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"DOI": "10.1099/ijsem.0.004526",
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"url": "https://doi.org/10.1099/ijsem.0.004526"
} | Two Gram-stain-negative, aerobic, non-motile bacteria, designated KMS-5T and CYK-10T, were isolated from freshwater environments. 16S rRNA gene sequence similarity results indicated that these two novel strains belong to the family Rhodobacteraceae. Strain KMS-5T is closely related to species within the genus Tabrizicola (96.1-96.8 % sequence similarity) and Cypionkella (96.5-97.0 %). Strain CYK-10T is closest to Rhodobacter thermarum YIM 73036T with 96.6 % sequence similarity. Phylogenetic analyses based on 16S rRNA gene sequences and an up-to-date bacterial core gene set showed that strain KMS-5T is affiliated with species in the genus Tabrizicola and strain CYK-10T is placed in a distinct clade with Rhodobacter blasticus ATCC 33485T, Rhodobacter thermarum YIM 73036T and Rhodobacter flagellatus SYSU G03088T. These two strains shared common chemotaxonomic features comprising Q-10 as the major quinone, phosphatidylethanolamine, phosphatidylglycerol and phosphatidylcholine as the principal polar lipids, and C18 : 1 ω7c as the main fatty acid. The average nucleotide identity, average amino acid identity and digital DNA-DNA hybridization values between these two novel isolates and their closest relatives were below the cut-off values of 95-96, 90 and 70 %, respectively, used for species demarcation. The obtained polyphasic taxonomic data suggested that strain KMS-5T represents a novel species within the genus Tabrizicola, for which the name Tabrizicola oligotrophica sp. nov. is proposed with KMS-5T (=BCRC 81196T=LMG 31337T) as the type strain, and strain CYK-10T should represent a novel species of the genus Rhodobacter, for which the name Rhodobacter tardus sp. nov. is proposed with CYK-10T (=BCRC 81191T=LMG 31336T) as the type strain. | 2022-12-09T00:18:33.882Z |
34,016,735 | {
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"DOI": "10.1109/78.80859",
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} | The use of pitch predictors in linear predictive coding systems is an efficient way to represent periodicity in the speech signal. Typically, the predictor is described by one parameter representing the delay in samples and 1 to 3 predictor coefficients can provide interpolation for periodicities that are not a multiple of the sampling interval and allow for a frequency-dependent gain. The authors describe a first-order pitch predictor whose delay is specified as an integer number of samples plus a fraction of a sample at the current sampling frequency. This realization has a better performance than conventional multiple coefficient predictors and leads to more efficient coding of the predictor parameters. > | 2022-12-12T05:08:40.135Z |
5,641,756 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1002/mus.20844",
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"url": "https://epublications.marquette.edu/cgi/viewcontent.cgi?article=1017&context=exsci_fac"
} | The magnitude of failure in voluntary drive after fatiguing contractions of different intensities in men and women is not known. The purpose of this study was to compare the time to task failure and voluntary activation of men and women for a sustained isometric contraction performed at a low and high intensity with the elbow flexor muscles. Nine men and nine women sustained an isometric contraction at 20% and 80% of maximal voluntary contraction (MVC) force until task failure during separate sessions. The men had a shorter time to failure than women for the 20% but not the 80% MVC task. Voluntary activation was reduced to similar levels for the men and women at the end of the fatiguing contractions but was reduced less after the 80% MVC task than the 20% MVC contraction. Twitch amplitude was reduced similarly at task failure for both sexes and to similar levels at termination of the 20% and 80% MVC tasks. The rate of change in mean arterial pressure was the main predictor of time to failure for the low‐force sustained contraction. These results suggest that women experienced greater muscle perfusion, less peripheral fatigue, and a longer time to task failure than men during the low‐force fatiguing contraction. However, the low‐force task induced greater central fatigue than the high‐force contraction for both men and women. Thus, low‐force, long‐duration fatiguing contractions can be used in rehabilitation to induce significant fatigue within the central nervous system and potentially greater neural adaptations in men and women. Muscle Nerve, 2007 | 2022-12-16T11:18:27.703Z |
21,047,052 | {
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"ArXiv": null,
"DOI": "10.1677/ERC-07-0154",
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} | Arginine vasopressin (AVP), a vasoactive peptide hormone that binds to three G-protein coupled receptors (V1R, V2R, and V3R), has long been known to activate V1R and elicit mitogenesis in several cell types, including adrenal glomerulosa cells. However, in the mouse Y1 adrenocortical malignant cell line, AVP triggers not only a canonical mitogenic response but also novel RhoA-GTP-dependent mechanisms which downregulate cyclin D1, irreversibly inhibiting K-ras oncogene-driven proliferation. In Y1 cells, AVP blocks cyclin D1 expression, induces senescence-associated beta-galactosidase (SAbeta-Gal) and inhibits proliferation. However, ectopic expression of cyclin D1 renders Y1 cells resistant to both SAbeta-Gal induction and proliferation inhibition by AVP. In addition, ectopic expression of the dominant negative RhoAN19 mutant blocks RhoA activation, yielding Y1 cell sub-lines which are no longer susceptible to cyclin D1 downregulation, SAbeta-Gal induction, or proliferation inhibition by AVP. Furthermore, inhibiting RhoA with C3 exoenzyme protects Y1 cells from AVP proliferation inhibition and SAbeta-Gal induction. On the other hand, AVP treatment does not activate caspases 3 and 7, and the caspase inhibitor Ac-DEVD-CMK does not protect Y1 cells from proliferation inhibition by AVP, implying that AVP does not trigger apoptosis. These results underline a pivotal survival activity of cyclin D1 that protects K-ras oncogene-dependent malignant cells from senescence. | 2022-12-18T16:54:58.769Z |
204,820,910 | {
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"ArXiv": null,
"DOI": "10.1109/SIPROCESS.2019.8868387",
"MAG": "2980317737",
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} | Physically unclonable functions are lightweight, secure primitives based on inherent variance of integrated circuits. Its security of resistance against machine learning attract more attention. Many improved APUF structures reduce stability while improving resistance to machine learning attack. In this paper, we propose a novel racing arbiter physically unclonable function (R-APUF) which has resistance against machine learning attack while keep an acceptable reliability. The proposed R-APUF’s path consists of several cascaded sub-chains based on MAX (MIN) operation, which return a MAX (MIN) delay of multi-channel. Software simulation and FPGA implementation are applied to evaluate the performance of the proposed PUF. Evolution strategy used to predict 4-channel 2-stage R-APUF maintain 75% prediction accuracy, while this structure keeps a 94.737% reliability closed to normal APUF. | 2022-11-26T07:56:31.553Z |
187,749,600 | {
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"ArXiv": null,
"DOI": "10.2991/cssdre-18.2018.3",
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"license": "CCBYNC",
"status": "GOLD",
"url": "https://download.atlantis-press.com/article/25896308.pdf"
} | This article proves that one of the main conditions of overcoming technological inferiority and modernization of the Russian economy is vigorous innovative activity since many branches of production have considerably exhausted both intensive and extensive possibilities of development. To reinforce innovative activity there must be innovative potential of regions. Innovative potential of regions is a key factor to achieving economic growth and improving quality of life of the population. The article suggests methodology of integral evaluation of innovative potential of the regions which allows to estimate the innovative development level of territories and to carry out interregional comparisons. | 2022-01-27T09:59:25.833Z |
114,133,661 | {
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"ArXiv": null,
"DOI": "10.1177/2041419616648579",
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} | This article presents numerical simulations of tsunami waves that are generated using different experimental techniques in laboratory tests. Comparisons of the numerical predictions of the tsunami wave shapes with different experimental measurements of the wave shapes have been carried out, and a good agreement was obtained. Four different laboratory techniques to create tsunami waves were examined: a sudden release of a water column, a horizontal or vertical motion of a piston, and a rotation of a rigid plate. Comparison of waves of the same height that are formed by these four different methods shows that the horizontal piston motion produces the shortest wave, and the vertical piston motion produces the longest wave. The wave produced by a plate rotation is similar to the wave caused by the “water column release,” but it is slightly longer. It was found that different techniques produce different wave characteristics; therefore, selection of the proper laboratory technique requires some considerations including a comparison with the required real tsunami wave that should be simulated. It should be emphasized that this research aims at simulating the tsunami waves that are produced by different common laboratory techniques; however, it refrains from assessing the adequacy of any of this techniques to properly represent a real specific tsunami wave. Further to developing the computational procedures for tsunami wave simulations, this article extends the numerical study to examine the interaction of a tsunami wave with a rigid wall and investigate the dynamic pressure distribution on the wall surface. It was found that the peak pressure of a tsunami wave acting on a rigid wall that is produced by the horizontal piston has the lowest magnitude (among the waves of the same height, caused by these four techniques), while the pressure due to a rotational plate has the highest magnitude. | 2022-02-10T01:50:28.195Z |
245,262,919 | {
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"ArXiv": null,
"DOI": "10.1097/MD.0000000000028234",
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} | Abstract Background: The relationship between platelet-associated parameters and psoriasis has been controversial. The purpose of our meta-analysis was to assess whether platelet count, platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet distribution width (PDW) are associated with psoriasis. Methods: We performed a thorough documentation retrieval via PubMed, EMBASE, and Web of Science until June 2021. Pooled standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated using a random-effects model. Results: Overall, 22 studies involving 1749 patients with psoriasis and 1538 healthy controls were selected for the meta-analysis. The outcomes showed that platelet count presented non-significant differences between psoriatic patients and normal individuals (SMD = 0.12, 95% CI = −0.07 to 0.32, P = .210), while PLR (SMD = 0.28, 95% CI = 0.03–0.53, P = .031), MPV (SMD = 0.55, 95% CI = 0.30–0.79, P < .001), and PDW (SMD = 0.29, 95% CI = 0.03–0.55, P = .027) were remarkably greater in the psoriatic patients than in the healthy individuals, and similar results were found in subgroup analyses. The analytical results of susceptibility revealed that the outcomes were robust, and no evidence of substantial publication bias was identified. Conclusion: Patients with psoriasis present significantly higher PLR, MPV, and PDW than healthy individuals, suggesting that psoriasis is accompanied by low-grade systemic inflammation and platelet activation. | 2022-05-21T21:22:45.477Z |
120,465,966 | {
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"DOI": "10.1088/0256-307X/25/2/051",
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} | We investigate the Kerr nonlinearity of a V-type three-level atomic system where the upper two states decay outside to another state and hence spontaneous generated coherence may exist. It is shown that dark state and hence perfect transparency present under certain conditions. Meanwhile, the Kerr nonlinearity can be controlled by manipulation of the decay rates and the splitting of the two excited states. Therefore, enhanced Kerr nonlinearity without absorption can be obtained under proper parameters. | 2022-07-09T02:57:10.180Z |
190,036,958 | {
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"ArXiv": null,
"DOI": "10.14746/pst.2011.25.16",
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"license": "CCBYNCND",
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"url": "https://pressto.amu.edu.pl/index.php/pst/article/download/4116/4183"
} | The article deals with the issue of television broadcast of religious events and in particular of the accompanying commentary. The case study pertains to the broadcast of the Eucharistic procession during the feast of Corpus Christi in TVP Polonia on June 23, 2011. Analysis of the media message showed that the task of the commentator and producer of the programme should consist in bringing out the rich variety of dimensions of the presented religious event. In the case of the Eucharistic procession those dimensions are first of all cultic, christocentric, sanctifying and history of salvation, and secondly the public and semeiological dimensions of the cultic act. Since the programme of the new evangelization asserts that the Church strives to introduce the issue of the proclamation of the Kingdom of God to the modern world also through mass media, it seems that the postulate of such a television broadcast which would show the true identity of the Christian community is valid and timely. | 2022-09-16T03:16:23.861Z |
252,777,063 | {
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"ArXiv": null,
"DOI": "10.53391/mmnsa.2022.015",
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},
"license": "CCBY",
"status": "HYBRID",
"url": "https://mmnsa.org/index.php/mmnsa/article/download/36/31"
} | The aim of the paper is to study a cancer model based on anti-angiogenic therapy and radiotherapy. A set-valued analysis is carried out to control the tumor and carrying capacity of the vasculature, so in order to reverse tumor growth and augment tumor repair. The viability technique is used on an augmented model to solve the control problem. Obtained control is a selection of set-valued map of regulation and reduces tumor volume to around zero. A numerical simulation scheme with graphical representations and biological interpretations are given. | 2022-10-21T00:30:54.612Z |
252,772,087 | {
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"DOI": "10.53625/ijss.v2i2.3068",
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"url": "https://bajangjournal.com/index.php/IJSS/article/download/3068/2203"
} | HIV continues to be a major global public health problem. A person infected with HIV will experience a gradual decline in immunity and will develop AIDS. The highest rates of HIV-infected cases were reported in the age groups of 25-49 years and 20-24 years. However, there is a surprising fact about the 15-19 year old group which is a group of teenagers. The risk of HIV infection in teenagers is caused by several factors. One of these factors is the level of knowledge. Teenager knowledge about free sex and HIV/AIDS transmission is still low. Based on data obtained from the P2P Division report of the Batam City Health Office, HIV cases has decreased compared to 2020 as many as 541 cases to 484 cases in 2021 with the largest distribution of cases in the Lubuk Baja District area with 245 HIV sufferers. The Covid-19 pandemic has hampered efforts to control disease, including controlling HIV/AIDS, especially in Batam City, including educational activities related to HIV/AIDS, which have stalled due to restrictions on mobility. The purpose of this study was to determine the relationship between the level of knowledge of teenagers about HIV/AIDS with HIV/AIDS preventive behavior during the Covid-19 pandemic at SMAS Kartini, Batam City. This type of correlation research with cross sectional approach. Data were obtained from distributing questionnaires to students of SMA Kartini City, Batam aged 15-18 years, totaling 74 samples. The results showed that 36 respondents with good knowledge had good behavior in preventing HIV/AIDS transmission, 35 respondents (97.2%) and 1 respondent (2.8%). There are 29 respondents with sufficient knowledge, namely 28 respondents (96.5%) who behave well in preventing HIV/AIDS transmission and 1 respondent (3.5%). Lack of knowledge of 9 respondents, namely those who behave well in preventing the transmission of HIV/AIDS. There is no significant relationship between the level of knowledge and prevention behavior (p=1,000). In conclusion, there is no relationship between the level of knowledge of teenagers about HIV/AIDS with HIV/AIDS prevention behavior during the COVID-19 pandemic at SMAS Kartini, Batam City, in the 2021-2022 academic year. | 2022-10-14T00:54:14.881Z |
44,134,344 | {
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"DOI": "10.1093/femspd/fty015",
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"url": "https://academic.oup.com/femspd/article-pdf/76/4/fty015/25008841/fty015.pdf"
} | Abstract Menstrual toxic shock syndrome is associated with vaginal colonization by Staphylococcus aureus strains that encode toxic shock syndrome toxin 1 (tst+). Interestingly, a small proportion of women are colonized by S. aureus tst+ but do not have symptoms of toxic shock syndrome. Here we sought to determine if differences in the species composition of vaginal bacterial communities reflect a differential risk of colonization by S. aureus capable of producing toxic shock syndrome toxin 1 (TSST‐1). The composition of vaginal communities of women that were or were not colonized with S. aureus tst+ were compared based on terminal restriction fragment length polymorphism (T‐RFLP) profiles and sequences of cloned 16S rRNA genes. There were no detectable differences in community composition or species rank abundance between communities of women vaginally colonized with S. aureus tst+ as compared to those that were not. Phylogenetic analysis of cloned 16S rRNA gene sequences showed that the predominant members of communities of women colonized with S. aureus tst+ were indistinguishable from those of other healthy women. The data suggest that the numerically dominant members of vaginal communities do not preclude colonization and proliferation of S. aureus tst+ within indigenous microbial communities of the vagina. | 2022-11-18T00:40:30.650Z |
136,205,003 | {
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"DOI": "10.1002/APP.45212",
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} | Processing strategies were developed to manufacture poly(lactic acid) (PLA) blown films without melt strength enhancers (MSEs). The effects of processing temperature on PLA's melt properties (shear and elongational viscosities), PLA grades, and other processing conditions [ratio of take-up roller to extruder's rotational screw speeds or processing speed ratio (PSR) and internal air pressures] on film's blow-up ratio were examined. Experimental results indicate that extrusion-blown amorphous and semicrystalline PLA films can be successfully manufactured without MSEs by controlling melt rheology through processing temperature and other extrusion processing conditions. PLA processed at lower extrusion temperature had higher melt viscosities, which favored the formation of stable films depending on the PSR and internal air pressure used. Inappropriate control of PSR and internal air pressure led to unstable films with various processing defects such as melt sag, bubble dancing, or draw resonance, irrespective of the lower extrusion processing temperature. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45212. | 2022-12-03T21:02:31.571Z |
46,722,074 | {
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"DOI": "10.1002/bjs.4691",
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} | Abdominal aortic aneurysm (AAA) repair is associated with a systemic inflammatory response. This inflammatory response probably arises as a result of an ischaemia–reperfusion injury to the legs and gastrointestinal tract. In this study the relative contributions of these areas to the inflammatory response were assessed during elective AAA repair. | 2022-09-05T11:12:24.504Z |
36,145,269 | {
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"DOI": "10.1088/0953-8984/24/16/164208",
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"url": "https://europepmc.org/articles/pmc3324287?pdf=render"
} | The recently demonstrated functionality of an aqueous quadrupole micro- or nano-trap opens a new avenue for applications of Paul traps, like confinement of a charged biomolecule which requires a water environment for its chemical stability. Besides the strong viscosity forces, the motion of a charged particle in the aqueous trap is subject to dielectrophoretic and electrophoretic forces. In this study, we describe the general conditions for stability of a charged particle in an aqueous quadrupole trap. We find that for typical micro-trap parameters, the effects of both dielectrophoresis and electrophoresis significantly influence the trap stability. In particular, an aqueous quadrupole trap could play the role of a synthetic virtual nanopore for the third generation of DNA sequencing technology. | 2022-12-17T20:54:13.483Z |
214,787,129 | {
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"DOI": "10.3390/polym12040779",
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"PubMedCentral": "7240670"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4360/12/4/779/pdf?version=1586100900"
} | High-internal-phase emulsion-templated macroporous polymers (polyHIPEs) have attracted much interest, but their surface functionalization remains a primary concern. Thus, competitive surface functionalization via physical self-assembly of macrosurfactants was reviewed. Dendritic and diblock-copolymer macrosurfactants were tested, and the former appeared to be more topologically competitive in terms of solubility, viscosity, and versatility. In particular, hyperbranched polyethyleneimine (PEI) was transformed into dendritic PEI macrosurfactants through click-like N-alkylation with epoxy compounds. Free-standing PEI macrosurfactants were used as molecular nanocapsules for charge-selective guest encapsulation and robustly dictated the surface of a macroporous polymer through the HIPE technique, in which the macroporous polymer could act as a well-recoverable adsorbent. Metal nanoparticle-loaded PEI macrosurfactants could similarly lead to polyHIPE, whose surface was dictated by its catalytic component. Unlike conventional Pickering stabilizer, PEI macrosurfactant-based metal nanocomposite resulted in open-cellular polyHIPE, rendering the catalytic sites well accessible. The active amino groups on the polyHIPE could also be transformed into functional groups of aminopolycarboxylic acids, which could efficiently eliminate trace and heavy metal species in water. | 2022-12-23T01:53:09.147Z |
214,096,784 | {
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"DOI": "10.24919/2308-4634.2019.182240",
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} | The leading line of materials presented in the article is vectorized to reveal and substantiate the coexistence and synthesis of modern and traditional, innovative and enduring, integrated and substantive as actual, conceptual and inalienable concepts in the discourse on the globalization processes taking place in the present world, in particular on the concepts of transition of all mankind to a fundamentally new post-industrial civilization in general and the planetary society in particular. In the specified way, under a particular angle of view and aspects of scientific vision, the essential and functional contexts of folk art as a special field of cultural and creative progress of Ukrainians are highlighted. Through the prism of the analysis of its cognitive, developmental and educational potentials, their place and role in the field of the formation of erudite, competent, versatile personality capable of penetrating into the modern society, to meet its demands, interests and norms of the present dynamic life is determined. Putting the subject of research into the rank of actual and effective components of moderation of modern artistic education, the author argues that moving forward, opening the new, giving preference to a modern, innovative, globalized modelling of the content and forms of the present life, should not neglect the achievements of the past, the traditions generated by him and customs of material, spiritual, general cultural nature, since without them the present and future loses its meaningful meaning. In the justification, the above emphasis is placed on the fact that the development of students as young generations, on the true bases of domestic art, must necessarily include the study of “folk” branch. It is about understanding of one’s national background, knowledge of the origins, ways of development and general features of artistic creation of folk artists, penetration of the principles of perception of the world, ideas and concepts of artistic expression of the real and the imaginary. All this is so significant that without that, even the simplest algorithm for the acquisition of artistic education will be destroyed and the process of learning, upbringing and development in this area will become unproductive. It follows that these vectors and the content of artistic and aesthetic education, based on the idea of the revival of national culture, artistic traditions, achievements, are indisputably popular, relevant and extremely important and significant both for the younger generations in particular and for society as a whole. | 2022-01-27T08:19:26.173Z |
19,335,268 | {
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} | For the past sixteen years I have been working in the field of geriatrics and gerontology. During that time I have discovered a number of basic p i n ciples of how to work successfully with older patients. What I know I have not learned from textbooks, but from the real experts on aging, older people themselves. I would like to share these principles with you in the hope of facilitating your work with older patients. I am also offering these principles as a tribute to all older persons who, in my opinion, constitute a group of elite survivors and pioneers, laboring at the last great frontier: confronting their own aging experience. I have been trained as a psychiatrist. But in that training I was not given one whit of information about geriatric psychiatry, that is psychiatry as it applies to older patients. The field literally did not exist. If I helped to create that field, then I am pleased. But I have gained far more than I have contributed. Moreover, I continue to learn, the ultimate reward for the academician. While speaking as a psychiatrist, I feel that the principles that I will discuss apply to the helping professions generally: to all medical specialties, especially internal medicine, psychiatry, and family medicine, but also to the allied health and the social service professions. In fact, it would be foolish to think that older people would want to teach anything that was of value to psychiatrists only. These, then are the principles that I would like to share with you. | 2022-09-11T06:17:18.903Z |
136,486,169 | {
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} | Spatial light modulator controlled resonant feedback random lasing is a promising method for the authentication of tamper evident seals. We report preliminary results of random lasing in Rhodamine 6G dye-doped polyurethane with dispersed ZrO2 nanoparticles. | 2022-09-11T23:22:46.500Z |
78,033,299 | {
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} | Betamethasone dipropionate, 0 05%, in a propylene glycol ointment vehicle (Diprolene Ointment(R)) was administered to forty-seven patients with resistant psoriasis or other resistant steroid-responsive dermatoses in a 2-week open study. The efficacy and tolerance of this new topical corticosteroid preparation were evaluated. Response was rapid, as illustrated by the sharp decrease in the severity of signs and symptoms. All patients improved. Lesions cleared in 25.5% of cases (twelve patients), showed marked improvement in 66% (thirty-one patients) and showed moderate improvement in 8.5% (four patients). Six patients developed folliculitis which did not necessitate discontinuation of Diprolene therapy. No changes in adrenal function were detected. | 2022-09-08T23:55:02.868Z |
146,809,821 | {
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患者因腰背阵发性钝痛1个月就诊，检查显示骨密度升高，未治疗。入院前5d症状加重，无明显胃肠道症状，进一步检查确诊为胃癌（印戒细胞癌）。提示临床中对腰背疼痛伴骨密度升高的患者应提防恶性肿瘤骨转移的可能。.
| 2022-12-11T22:22:31.424Z |
43,234,199 | {
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} | A case in which there was a shunt between systemic veins and the left heart in superior vena cava syndrome due to lung cancer is reported. Superior vena cava syndrome developed one and a half years after right upper lobectomy with combined resection of thoracic wall. Radionuclide venography from the right antecubital vein showed immediate visualization of the left ventricle and aorta, before the right atrium and right ventricle were seen. In the superior vena cava syndrome due to a malignant tumor, this rare pathway as well as usual collaterals should be considered. | 2022-12-20T18:51:19.510Z |
171,211,206 | {
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} | Este trabalho investigou a integracao de um modulo educacional com base em atividades de modelagem computacional no estudo de um topico especifico de Ciencias: o Oscilador Harmonico Simples (OHS). O estudo consistiu do planejamento, implementacao, teste e avaliacao do modulo educacional. Os instrumentos de coleta de dados foram divididos em duas partes: as atividades de modelagem e a planilha de avaliacao do modulo educacional. O teste foi realizado com professores de Fisica do Ensino Medio cursando pos-graduacao na Universidade Federal do Espirito Santo. Os dados da avaliacao do modulo educacional demonstraram a adequacao ao objetivo a que se propos, sendo que, foram sugeridas modificacoes que foram implementadas para utilizacao futura. Por outro lado, os resultados das atividades de modelagem mostraram que os professores puderam confrontar o entendimento previo sobre os conceitos abordados com os resultados da simulacao e, em alguns casos, reforcar as concepcoes e em outros evolui-las ao conhecimento cientifico. | 2022-02-08T16:55:59.817Z |
169,897,092 | {
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"DOI": "10.1596/1813-9450-8482",
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} | This paper proposes a theory of urban land use with endogenous property rights. Socially heterogeneous households compete for where to live in the city and choose the type of property rights they purchase from a land administration which collects fees in inequitable ways. The model generates predictions regarding sorting and spatial patterns of informality consistent with developing country cities. It also highlights non-trivial effects of land administration reforms in the presence of pecuniary externalities, possibly explaining why elites may have an interest in maintaining inequitable land administrations that insulate them from competition for land from the rest of the population. | 2022-08-24T13:07:42.353Z |
68,874,868 | {
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"DOI": "10.4324/9780203891094",
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} | A New Breed of Dictionary for the Human Service Worker in the 21st Century. McPheeters, A Definition of Human Services. The Father of Human Services. McPheeters, Early Steps in Human Services Education. Human Services Terms A to Z. Resources. Statistical Tests Used in Research Parametric Tests Nonparametric Tests Major Psychoeducational Diagnostic Tools Sources for Obtaining Ethical Guidelines and Other Pertinent Information Popular Description Medicines for Psychiatric Conditions Natural Remedies for Mental Health Common Prescription Medicines for General Medical Conditions | 2022-09-13T20:47:32.039Z |
222,353,694 | {
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} | Objectives: This study aimed to assess the association of the quality scores of hotline psychological intervention and the reduction of subsequent suicidal acts among high suicidal risk callers. Methods: High-risk callers at a national crisis hotline service in China were recruited and prospectively followed for up to 3 months after receiving a hotline psychological intervention. The quality of the intervention was evaluated by supervisors who listened to the tape-recorded calls using the Counseling Skills Rating Scale for Psychological Support Hotlines, which assessed three counseling domains: process, attitude and communication skill. The primary outcome was the occurrence of suicidal acts during the follow-up period. Secondary outcomes were before versus after changes during the intake intervention call in hopefulness, psychological stress and suicide intention reported by the callers. Results: Over the 3-month follow-up, 45 of 778 high-risk callers reported 61 suicide attempts, and 3 other callers died by suicide. Subsequent suicidal act was significantly more common in callers classified as being at higher risk during the intake call. Higher scores on the quality of suicidality assessing of the Counseling Skills Rating Scale for Psychological Support Hotlines were associated with reduced risk of suicidal acts during follow-up (hazard ratio = 0.38, 95% confidence interval = [0.18, 0.85]). Higher scores on the communication skill domain were associated with increases in hopefulness (β = 0.09) after the intervention, and higher scores on the counseling process domain (β = −0.12) and higher suicidal risk scores (β = −0.12) were associated with decreased suicide intention after intervention. Conclusion: Several characteristics of a hotline intervention for suicide prevention were associated with decreased risk of suicidal acts during follow-up. Intervention skill training for hotline operators should emphasize these specific counseling skills. | 2022-11-29T07:15:16.437Z |
233,839,867 | {
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"DOI": "10.1088/1742-6596/1802/4/042084",
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"url": "https://doi.org/10.1088/1742-6596/1802/4/042084"
} | Requirement demonstrating is an important link of C4ISR construction. The paper design a requirement demonstrating architecture framework of C4ISR based on the research on DOD2.0. The paper describe how to design capability requirement view, information requirementview, services requirement view, systems requirement view, project requirement view and standards requirement view emphatically. Project viewpoints have great significance in the field of C4ISR requirement demonstrating. | 2022-12-16T15:47:34.262Z |
223,597,284 | {
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"DOI": "10.47310/IAJAPN.2020.V01I01.002",
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} | Background: Nurse‟s knowledge regarding medication error can affect by many factors such as personal cause (stress, exhaustion), predisposing factor (long working shift, busy environmental setting), lack of experience and knowledge about medication error. Objective: The aim of this study is to assess nurses‟ knowledge regarding medication error. Methods: A descriptivecorrelation study was conducted.108 nurses were recruited conveniently. Two sample t-test, analysis of variance analysis (ANOVA) and correlation were used to analyze the data by SPSS version 23. Result: The result showed that mean knowledge score regarding medication error was 18.74 (±4.75) out of 30 total score, which indicated moderate knowledge level. There were significant relationships between nurses‟ knowledge regarding medication error with age (p =.005), service experience (p =.039), monthly income (p =.000) and level of education (p = .000). Nurses who were in more service experience, held B.Sc. in nursing and who were in high monthly income, they have moderate level of knowledge score regarding medication error. It also showed that, nurses who were in less service experience, held diploma in nursing and who were in low monthly income, they have low level of knowledge score regarding medication error. Conclusion: The knowledge is the matters toward safe administration of medication and most of the nurses strongly agree to continue education program for prevention of medication error. Intensive regular retraining programs should be held aiming to improve nurses‟ pharmacological information, encourage to report medication errors, hospital should provide continuing education to reduce medication error especially; younger and diploma degree nurses and hospital managers should respond to errors in a positive ethical and logical manner in order to enhance patient safety. | 2022-12-25T22:58:53.603Z |
244,142,213 | {
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"DOI": "10.1109/icrito51393.2021.9596464",
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} | Agriculture crop prediction is a challenging and interesting problem domain for the computer community. The computer machine helps to improve the productivity of the crop with such predication. This paper illustrates a research model which provides the predications of the wheat crop in the Rajasthan region of India. This paper uses feedforward neural network models to accomplish the task of predication for the wheat crop. These models are trained with three different feedforward neural network architectures namely multi-layer perception feedforward generalized regression and radial basis neural network. There is feature scaling method was used for normalization of large previous year's crop detail data which has been obtained by agriculture department of Rajasthan government. The simulation results indicate the better prediction with 97.75% accuracy found by the feedforward neural network model trained with backpropagation learning rule in comparison to Generalized regression neural network and Radial basis neural network. | 2022-12-26T19:05:03.037Z |
208,862,885 | {
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"DOI": "10.3760/CMA.J.ISSN.0254-5098.2004.03.038",
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} | 随着我国经济发展,医疗事业进步,一些医疗单位放疗科使用医用加速器替代60Co远距离治疗机(简称60Co治疗机).笔者单位拟装备VARIAN2100医用加速器,最大加速电压10 MV.如果在医用加速器初级X射线(有用射线束)方向装置一个射线挡束块(Beam Stop Block)(也可以将加速器配重改装成挡束块),挡束块由计算机实现自动连锁控制,能随着加速器大臂同步旋转,时刻保持对初级X射线的屏蔽.使用电子束照射时,能自动缩回到机腹内,避免电子束在挡束块中产生的次级韧致辐射,从而解决医用加速器安装60Co机房的辐射屏蔽防护问题. | 2022-02-08T03:49:50.840Z |
54,449,273 | {
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"DOI": "10.1109/ICMMT.2018.8563549",
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} | In this paper, a graphene reflective metasurface for generating spin-controlled vortex waves is proposed in the terahertz domain. By patterning the graphene cells into the phase distribution of corresponding topological modes, the proposed graphene metasurface is capable of generating a vortex beam carrying orbital angular momentum (OAM). More importantly, taking advantages of the Pancharatnam-Berry (PB) phase method, a spin-controlled OAM beam can be achieved in the reflective orientation. Compared with line-polarized OAM, the proposed spin-controlled beams can provide one more degree of freedom for THz wireless communication. Numerical simulations results demonstrate the spin vortex waves with various topological modes can be flexibly achieved by this graphene metasurface, which paves a way to generate spin OAM vortex waves for communication systems in terahertz. | 2022-02-11T21:05:09.972Z |
104,838,174 | {
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"DOI": "10.1063/1.5043106",
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"url": "https://aip.scitation.org/doi/pdf/10.1063/1.5043106"
} | The ambient pressure temperature dependence of the magnetization (M) in P1-xSrxCoO3 series (x = 0.4, 0.5, 0.55 and 0.6) indicates the onset of ferromagnetic ordering at high temperatures (TC = 214-226K) and a step-like anomaly at lower temperatures (TS = 69-120 K). In this report we present the pressure dependence of magnetization and zero-field thermal expansion studies for a representative sample x = 0.4. The step-like anomaly in M(T) around TS = 69 K is accompanied by a pronounced peak in thermal expansion coefficient. The application of hydrostatic pressure of P = 1.16 GPa increases TS by 15 K, which is much larger than the increase of the ferromagnetic Curie temperature (ΔTC = 4 K) under the same pressure. The anomalous increase of TS under pressure is attributed to the occurrence of magnetization rotation at a temperature higher than TS = 69 K triggered by the stabilization of low temperature tetragonal phase at the expense of high temperature orthorhombic phase.The ambient pressure temperature dependence of the magnetization (M) in P1-xSrxCoO3 series (x = 0.4, 0.5, 0.55 and 0.6) indicates the onset of ferromagnetic ordering at high temperatures (TC = 214-226K) and a step-like anomaly at lower temperatures (TS = 69-120 K). In this report we present the pressure dependence of magnetization and zero-field thermal expansion studies for a representative sample x = 0.4. The step-like anomaly in M(T) around TS = 69 K is accompanied by a pronounced peak in thermal expansion coefficient. The application of hydrostatic pressure of P = 1.16 GPa increases TS by 15 K, which is much larger than the increase of the ferromagnetic Curie temperature (ΔTC = 4 K) under the same pressure. The anomalous increase of TS under pressure is attributed to the occurrence of magnetization rotation at a temperature higher than TS = 69 K triggered by the stabilization of low temperature tetragonal phase at the expense of high temperature orthorhombic phase. | 2022-08-20T18:07:21.693Z |
204,998,924 | {
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"DOI": "10.1111/cga.12259",
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} | To evaluate the association between the single nucleotide polymorphism (SNP) rs227493 in the MEOX2 gene and nonsyndromic cleft palate only, this research was conducted as a case–control study by comparing a nonsyndromic cleft palate only group with an independent, healthy, and unaffected control group who were both examined by specialists. Based on clinical examination and medical records, we analyzed a total of 570 DNA samples, including 277 cases and 293 controls, which were extracted from dry blood spot samples collected from both the Odonto and Maxillofacial Hospital in Ho Chi Minh City and Nguyen Dinh Chieu Hospital in Ben Tre province, respectively. The standard procedures of genotyping the specific SNP (rs2237493) for MEOX2 were performed on a StepOne Realtime PCR system with TaqMan SNP Genotyping Assays. Significant statistical differences were observed in allelic frequencies (allele T and allele G) between the non‐syndromic cleft palate only and control groups in female subjects, with an allelic odds ratio of 1.455 (95% confidence interval: 1.026–2.064) and P < 0.05. These study findings suggest that nonsyndromic isolated cleft palate might be influenced by variation of MEOX2, especially SNP rs2237493 in Vietnamese females. | 2022-10-14T13:28:58.329Z |
13,736,459 | {
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"DOI": "10.1177/0363546514543770",
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} | Background: Recent anatomic studies have confirmed the presence of a true ligament structure, the anterolateral ligament (ALL), in the anterolateral region of the knee. This structure is involved in the rotatory instability of the knee and might explain why some isolated reconstructions of the anterior cruciate ligament result in a residual pivot shift. Therefore, when considering the least invasive method for reconstruction of this structure, it is important to identify the corresponding bony landmarks on radiographic images. Purpose: To establish radiographic femoral and tibial landmarks for the ALL in frontal and lateral views. Study Design: Descriptive laboratory study. Methods: Ten unpaired cadaver knees were dissected. The attachments of the ALL were isolated and its anatomic parameters were quantified. Its origin and insertion were marked with a 2-mm-diameter metallic sphere, and radiographs were taken from frontal and lateral views. The obtained images were analyzed and the ALL parameters established. Results: The origin of the ALL in the lateral view was found at a point an average ± SD of 47.5% ± 4.3% from the anterior edge of the femoral condyle and about 3.7 ± 1.1 mm below the Blumensaat line. In the frontal view, the origin was about 15.8 ± 1.9 mm from the distal condyle line. The ALL insertion was an average of 53.2% ± 5.8% from the anterior edge of the lateral tibial plateau in the lateral view and 7.0 ± 0.5 mm below the lateral tibial plateau in the frontal view. In anatomic dissections, the origin of the ALL was 1.9 ± 1.4 mm anterior and 4.1 ± 1.1 mm distal to the lateral collateral ligament, and the insertion was 4.4 ± 0.8 mm below the lateral tibial plateau cartilage. Conclusion: The ALL origin on an absolute lateral radiograph of the knee is approximately 47% of the anterior-posterior size of the condyle and 3.7 mm caudal to the Blumensaat line. In a frontal radiograph, the ALL is 15.8 mm from the posterior bicondyle line. The ALL insertion is approximately 53.2% of the anterior-posterior size of the plateau in the lateral view and 7.0 mm below the articular line in the frontal view. Clinical Relevance: Knowledge of the anatomic landmarks of the ALL on radiography will permit minimally invasive surgical reconstruction with lower morbidity. | 2022-12-16T00:13:01.715Z |
97,972,896 | {
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"DOI": "10.1002/PRAC.19803220214",
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} | Studies on Sulphochlorination of Paraffins. VI. Studies on the Sulphochlorination of Individual Alkyl Chlorides
The products of sulphochlorination of individual C2–C7 alkyl chlorides were studied by means of 1H- and 13C-n.m.r. spectroscopy. Gaschromatographic determination of the isomers formed was possible after the reaction of the chloroalkane sulphochloride mixture with dimethyl amine in ether. In no case geminal chloroalkane sulphochlorides were formed. Vicinal chlorosulphochlorides are formed, but substitution in greater distance from the chlorine is preferred if possible. Thus higher alkyl chlorides yield only very little amounts of vicinal chloroalkane sulphochlorides. The relative rates of sulphochlorination of alkyl chlorides were determined by competitive reactions. | 2022-02-10T12:59:08.538Z |
97,391,516 | {
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"DOI": "10.1143/JJAP.11.931",
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} | A lithium chloride heated hygrometer is operated above the surface of a saturated solution of lithium chloride as well as above the water surface at various temperatures. On the curve representing the relation between the temperature and the electric resistance of the hygrometer, the break point is observed. The temperature of the break observed for the saturated solution agrees with the temperature of the solution. Corresponding temperature when used above the water surface is compared with published data of the water vapor pressure of the saturated solution vs. temperature, and also with published operating temperatures of practical hygrometers. It is concluded that the break corresponds to the phase transition between lithium chloride hydrate and the saturated solution formed on the hygrometer. | 2022-07-31T09:13:51.887Z |
78,703,491 | {
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} | A Bütterich, M Klein, H Hassel Coburg Universtity of Applied Sciences and Arts, Institute of Applied Health Sciences, Coburg, Germany Catholic University of Applied Sciences, Cologne, Germany Contact: [email protected] Background ,,That’s good! The rally by young and old‘‘, was the health program of the research project MACY, which was executed by the Coburg University of Applied Sciences and Arts and the Catholic University of Applied Sciences Cologne. Each region cooperated with three practice-partners. The aim was to improve the Health Literacy (HL) of people, aged 60 and over and adolescents between 11–14 years. Did the intergenerational HL-Intervention, amongst other things also promote a rising consumption of healthy food of the target groups (optimizing of the food consumptions with fruits/vegetables and drinks)? Methods In 11 multigeneration-spanning groups 87 elderly people and 92 adolescent participated in the intervention (22 meetings, of 90 minutes each) from January 2013 to July 2013. Nutrition was processed in 6 meetings. The questionnaire survey took place at three times of exhibition. The results refer to the prepost comparison. The data was analyzed with Wilcoxonand ttest. Results Older people and the adolescents improved their dietary habits. Both target groups increased their daily fruit consumption from 1 to 2 portions. The vegetable consumption didn’t changed. The older people decreased the consumption of sweets from 3 to less than 3 portions/week and the adolescents from 2 to 1 portion/day. Furthermore, the older people increased their daily amount of beverages from 6 to 8 glasses. From 86 % of the elderly people and 87 % of the adolescents the intergenerational cooperation was positively evaluated. Discussion The ,,That’s good!’’-rally was an effective intervention for the promotion of a healthy eating behavior of elderly people and adolescents. The sustainability of the project was ensured by the autonomous continuation of the rally and by the transfer in further facilities. Key messages The ,,That’s good!’’-rally was an effective intervention for the promotion of a healthy eating behavior of elderly people and adolescents The intergenerational HL-Intervention promoted, amongst other things a rising consumption of healthy food of the target groups 8th European Public Health Conference: Poster Walks 343 | 2022-08-06T07:03:35.699Z |
246,327,474 | {
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"DOI": "10.31713/ve120198",
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"status": "GOLD",
"url": "http://visnyk.nuwm.edu.ua/index.php/econ/article/download/ve120198/621"
} | У статті досліджено процес становлення централізації та державного управління в сфері охорони здоров’я, які стали основою сучасної медичної сфери в країнах Європи та в країнах, які розвивали свої соціально-економічні системи на європейських цінностях. Проведено огляд централізованих систем охорони здоров’я від первісного часу до середньовіччя. Визначено як основу європейської системи охорони здоров’я організацію медицини в прадавніх країнах Месопотамії, Єгипті, Греції, Римі та Китаї. | 2022-08-29T19:10:04.121Z |
109,217,332 | {
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"DOI": "10.1002/J.1538-7305.1972.TB02685.X",
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} | This paper discusses the scattering losses of dielectric slab waveguides that are caused by higher-order grating lobes of the sinusoidally distorted core-cladding interface. The results of this paper are used in a companion paper to evaluate the radiation losses of multimode guides with intentional mode coupling. An exact system of equations is derived for the amplitudes of all grating orders. This system is used to derive first- and second-order approximations that hold for small amplitudes of the sinusoidal interface distortion. The theory is used to derive formulas for the average power loss coefficient for first- and second-order scattering processes. | 2022-09-12T21:31:00.195Z |
63,908,024 | {
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"DOI": "10.14288/1.0300436",
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} | High-throughput next-generation DNA sequencing has evolved rapidly over the past 20 years. The Human Genome Project published its first draft of the human genome in 2000 at an enormous cost of 3 billion dollars, and was an international collaborative effort that spanned more than a decade. Subsequent technological innovations have decreased that cost by six orders of magnitude down to a thousand dollars, while throughput has increased by over 100 times to a current delivery of gigabase of data per run. In bioinformatics, significant efforts to capitalize on the new capacities have produced software for the identification of deviations from the reference sequence, including single nucleotide variants, short insertions/deletions, and more complex chromosomal characteristics such as copy number variations and translocations. Clinically, hospitals are starting to incorporate sequencing technology as part of exploratory projects to discover underlying causes of diseases with suspected genetic etiology, and to provide personalized clinical decision support based on patients’ genetic predispositions. As with any new large-scale data, a need has emerged for mechanisms to translate knowledge from computationally oriented informatics specialists to the clinically oriented users who interact with it. In the genomics field, the complexity of the data, combined with the gap in perspectives and skills between computational biologists and clinicians, present an unsolved grand challenge for bioinformaticians to translate patient genomic information to facilitate clinical decision-making. This doctoral thesis focuses on a comparative design analysis of clinical decision support systems and prototypes interacting with patient genomes under various sectors of healthcare to ultimately improve the treatment and well-being of patients. Through a combination of usability methodologies across multiple distinct clinical user groups, the thesis highlights reoccurring domain-specific challenges and introduces ways to overcome the roadblocks for translation of next-generation sequencing from research laboratory to a multidisciplinary hospital environment. To improve the interpretation efficiency of patient genomes and informed by the design analysis findings, a novel computational approach to prioritize exome variants ii based on automated appraisal of patient phenotypes is introduced. Finally, the thesis research incorporates applied genome analysis via clinical collaborations to inform interface design and enable mastery of genome analysis. | 2022-09-13T21:38:31.086Z |
248,628,352 | {
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} | Background
Re-irradiation for recurrent gliomas is a controversial treatment option with no clear standard dose or concurrent systemic therapy.
Methods
This series represents a single-institution retrospective review of patients treated with re-irradiation for recurrent high-grade glioma. After 2012, patients were commonly offered concurrent bevacizumab as a cytoprotective agent against radiation necrosis. Kaplan-Meier method was used to estimate overall survival and progression-free survival. Cox proportional hazards regression was used to identify factors associated with overall survival and progression-free survival.
Results
Between 2001 and 2021, 52 patients underwent re-irradiation for a diagnosis of recurrent high-grade glioma. 36 patients (69.2%) had a histologic diagnosis of glioblastoma at the time of re-irradiation. The median BED10 (biological equivalent dose 10 Gy) of re-irradiation was 53.1 Gy. Twenty-one patients (40.4%) received concurrent bevacizumab with re-irradiation. Median survival for the entire cohort and for glioblastoma at the time of recurrence patients was 6.7 months and 6.0 months, respectively. For patients with glioblastoma at the time of recurrence, completing re-irradiation (HR 0.03, P < .001), use of concurrent bevacizumab (HR 0.3, P = .009), and the BED10 (HR 0.9, P = .005) were predictive of overall survival. Nine patients developed grade 3-5 toxicity; of these, 2 received concurrent bevacizumab and 7 did not (P = .15).
Conclusion
High dose re-irradiation with concurrent bevacizumab is feasible in patients with recurrent gliomas. Concurrent bevacizumab and increasing radiation dose may improve survival in patients with recurrent glioblastoma. | 2022-09-23T07:23:58.314Z |
83,869,410 | {
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} | A figueira (Ficus carica L.) vem se tornando uma das mais importantes plantas frutiferas cultivadas no sul e sudeste do pais. A formacao de mudas em viveiros, em comparacao com a estaquia direta no campo, vem sendo cada vez mais utilizada. Objetivou-se com este trabalho estudar a influencia da forma de acondicionamento sob frio no estabelecimento e sobrevivencia de mudas de figueira, cv. Roxo de Valinhos. Propagadas por estaquia, mudas de um ano de idade foram preparadas durante o periodo de inverno (julho) e colocadas para conservacao em câmara fria com temperatura de 8°C, divididas em 11 tratamentos, com delineamento inteiramente casualizado, contendo tres repeticoes e 18 mudas por parcela. Os tratamentos consistiram na forma de acondicionamento utilizando-se jornal, saco plastico, areia, serragem, parafina e algumas combinacoes desses materiais. O tempo de permanencia em câmara fria foi de 120 dias. Nesse periodo, foram avaliados, na instalacao do experimento e a cada 30 dias, os teores endogenos de aminoacidos e proteinas. Apos esse periodo, as mudas foram plantadas diretamente no campo, em sulcos espacados em 1 m e 0,20 cm entre plantas com delineamento em blocos casualizados com tres repeticoes e 14 mudas por parcela. Foi avaliado o crescimento das brotacoes ate 8 meses do plantio e, no final, a porcentagem de estacas brotadas que foram consideradas como plantas estabelecidas. O indice de vingamento atingiu, em media, 97,09% nos melhores tratamentos. | 2022-11-11T07:59:13.811Z |
157,903,172 | {
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} | NAEA Convention New York City March 2001 Lowenfeld: An other Look I t has becomecommonplace forus to dismiss or diminish the workofour forebears in art education. We either follow them unquestioningly and by canonizing their work, reduce it to a set of static, scripted, regimented, pedagogical norms, or we simplyconsign it a place in art education history where it can either languish without offense or become the playground of contemporary revisionists.So has it been with the work ofVtktor Lowenfeld and much of the developmental theory he cared and wrote about | 2022-12-18T00:30:53.561Z |
124,498,345 | {
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} | We investigate the dynamics of a system coupled to an environment by averaged semiquantum method. The theory origins from the time-dependent variational principle (TDVP) formulation and contains nondiagonal matrix elements. So it can be applied to study dissipation, measurement, and decoherence problems in the model (H = hS+hE +hI). In the calculation, the influence of the environment govern by differential dynamical equation is incorporated through a mean field. We have performed averaged semiquantum method for a spin-boson model, which reproduce the results from stochastic Schrodinger equation method and Hierarchical approach quite accurately. The problems, dynamics in nonequilibrium environments, have also been studied by our method. | 2022-02-09T18:27:50.320Z |
94,802,969 | {
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} | Highly ordered nano crystallized Ag2Se nanowires of diameter 200 nm have been successfully prepared through direct chemical method using Anodic Alumina Membrane (AAM) as a template; AgNO3 as cation precursor agent and Na2SeSO3 as Se precursor, respectively at room temperature. The qualitative analysis of the EDAX spectrum of nanowires shows that the atomic composition of Ag and Se in synthesized nanowires is close to 2:1 stoichiometry. XRD spectrum confirms orthorhombic structure. UV-Vis absorption spectrum provides estimation of the optical band gap 1.41 eV of nanowires. | 2022-09-07T03:03:37.461Z |
7,461,311 | {
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} | An endogenous enzyme present in cell surface extracts of Streptococcus sanguis strain G9B degraded the major salivary adhesin of the organism. The enzyme showed optimal activity between 50 and 65 degrees C and was inactivated at higher temperatures. The activity at these unusually high temperatures seemed to be a consequence of release from the cell surface since intact whole G9B cells showed greater activity at 37 degrees C. The enzyme was not found in culture supernatants of G9B cells. The pH range for the enzyme was between 5 and 9. It was inhibited by iodoacetic acid, Hg2+, Cu2+, EDTA, SDS, and PMSF, but not by TLCK, TPCK, soybean trypsin inhibitor, cysteine, dithiothreitol, leupeptin, Ca2+, Mg2+ or saliva. The enzyme did not show any activity against human or rabbit IgG or human IgA. Enzyme activity was also found in S. sanguis strains Adh- (a spontaneously occurring non-adherent mutant of G9B), and M-5. | 2022-11-18T00:16:54.468Z |
218,954,456 | {
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"url": "https://pubs.geoscienceworld.org/gsa/gsabulletin/article-pdf/133/1-2/100/5206752/100.pdf"
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The San Diego Formation, Pico Formation, Careaga Sandstone, and Foxen Mudstone of southern California are thought to be late Pliocene to early Pleistocene; however, numerical ages have not been determined. Following assessment of diagenetic alteration via multiple methods including scanning electron microscopy (SEM), X-ray diffraction (XRD), and minor elemental concentrations, we attempted to use strontium isotope stratigraphy to assign numerical ages. Using aragonitic fossils, we obtained ages of 2.0–1.85 Ma for the Careaga Sandstone and 2.0–1.75 Ma for the uppermost Foxen Mudstone, consistent with biostratigraphic work suggesting a Gelasian age for the Careaga Sandstone. Isotope ratios for aragonitic and calcitic fossils from the Pico Formation were poorly constrained, with the exception of one bed yielding ages of 5.1–4.3 Ma. Isotope ratios from the San Diego Formation were also inconsistent within beds, with the exception of two isolated outcrops that yielded ages of 5.0–4.5 Ma and 4.5–2.8 Ma, respectively. The age estimates for the Pico and San Diego Formations are older than most ages inferred from biostratigraphy. Noting that some aragonitic specimens from the San Diego Formation yielded isotope ratios indicative of ages as old as 19.4 Ma, we propose that some outcrops have been affected by diagenesis caused by groundwater flow through proximal granitic rocks and input from detrital sediment. Although we recommend that strontium isotope results for the Pico and San Diego Formations be interpreted with caution, the ages of the uppermost Foxen Mudstone and Careaga Sandstone can be confidently placed within the early Pleistocene. | 2022-11-22T17:55:06.254Z |
22,755,817 | {
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"DOI": "10.1021/JF050293L",
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} | The sorption behavior of diuron, imidacloprid, and thiacloprid was investigated using 22 soils collected in triplicate from temperate environments in Australia and tropical environments in Australia and the Philippines. Within the temperate environment in Australia, the soils were selected from a range of land uses. The average KOC values (L/kg) for imidacloprid were 326, 322, and 336; for thiacloprid, the values were 915, 743, and 842; and for diuron, the values were 579, 536, and 618 for the Ord (tropical), Mt. Lofty (temperate), and Philippines (tropical) soils, respectively. For all soils, the sorption coefficients decreased in the following order: thiacloprid > diuron > imidacloprid. There were no significant differences in sorption behavior between the tropical soils from the Philippines and the temperate soils from Australia. Sorption was also not significantly related with soil characteristics, namely, organic carbon (OC) content, clay content, and pH, for any of the three chemicals studied. When the data were sorted into separate land uses, the sorption of all three chemicals was highly correlated (P < 0.001) with OC for the rice soils from the Philippines. Sorption coefficients for all three chemicals were highly correlated with OC in temperate, native soils only when one extreme value was removed. The relationships between sorption of all three chemicals and OC in temperate, pasture soils were best described by a polynomial. Sorption coefficients for imidacloprid and thiacloprid determined in the temperate pasture soils remained fairly consistent as the OC content increased from 3.3 to 5.3%, indicating that, although the total OC in the pasture soils was increasing, the component of OC involved with sorption of these two compounds may have been remaining constant. This study demonstrated that the origin of the soils (i.e., temperate vs tropical) had no significant effect on the sorption behavior, but in some cases, land use significantly affected the sorption behavior of the three pesticides studied. The impact of land use on the nature of soil OC will be further investigated by NMR analysis. | 2022-12-17T23:31:43.397Z |
244,847,928 | {
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"DOI": "10.1002/admi.202101493",
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} | Si sources involved in the growth of Au–SiOx nanostructures are investigated through the rapid thermal annealing of gold thin films on SiO2/Si substrates with various SiO2 layer thicknesses (3, 25, 100, 500 nm) in a reducing atmosphere. This method reveals three Si sources whose involvement depends on the thickness of the SiO2 layers, i.e., Si diffusion from the substrate, and SiO from SiO2 decomposition and from Si active oxidation. Increasing thicknesses of the SiO2 layer hampers the Si diffusion and the decomposition of regions of the SiO2 layer, which decreases the concentrations of discovered regions weakening the Si active oxidation. These discovered regions appear in systems with a SiO2 layer of 25 or 100 nm, while they are absent for a 500 nm layer. Furthermore, Au–SiOx nanostructures of different shapes form in each system. Both behaviors indicate that the influence and transport mechanisms of the different Si sources are largely dependent on the thicknesses of the SiO2 layers and that they control the evolution of the Au–SiOx nanostructures. A clear understanding of the relationship between these thicknesses and the possible Si sources and their roles in the evolution of the nanostructures makes the tailored fabrication of nanostructures possible. | 2022-12-16T20:19:34.960Z |
234,374,876 | {
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"url": "https://jurnal.staip.ac.id/index.php/hasanah/article/download/11/14"
} | Penelitian ini dilatar belakangi dengan adanya mutu pendidikan yang rendah di berbagai pendidikan, sehingga perlu diadakan Sistem Penjaminan Mutu Internal Mutu Layanan Pendidikan dapat meningkat. Tujuan penelitian ini untuk mengetahui standar, pemetaan mutu, peencanaan, pelaksanaan, evaluasi, strategi faktor penghambat dan pendukung penjaminan mutu di SD Darul Hikam 2 dan SDN 200 Lewipanjang Kota Bandung.Penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif.Teknik pengumpulan data mengunakan observasi peran serta, wawancara mendalam, dan dokumentasi. Data dianalisis melalui reduksi data, penyajian data, penarikan kesimpulan, dan uji keabsahan datanya dengan triangulasi. Hasil temuan penelitian ini bahwa kedua sekolah ini secara keseluruhan sudah mengimplementasikan sistem penjaminan mutu internal dalam meningkatkan mutu layanan pendidikan di sekolahnya masing-masih dengan hasil baik karena paling rendah berada pada rentang 5,06 dan itu artinya termasuk kategori menuju SNP 3 dengan perolehan bintang 3. | 2022-12-31T18:35:41.307Z |
113,103,178 | {
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"DOI": "10.5958/2249-7307.2015.00165.6",
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} | Today one of the most important damage that threatens the social new order in the bureaucratic and administrative is the issue of corruption and administrative chaos that in front of the office health is considered as one of the most basic concern of executive authorities. Administrative system in any society is the executive arm of the political system in that community and its true or false Performance can sustain the political system or put it away from legitimacy. The fundamental attention to the administrative system in each society and exact pathology (administrative corruption) can be a great help to the policy makers of that community in which with timely diagnosis, they think about required solutions. In this context, this study sought to examine the affecting organizational factors relationship on the administrative health in fiscal affairs of organization in South Khorasan. Due to the nature of this study and according to the intended purpose, this study in terms method is correlation type and from purpose view is a practical one. A questionnaire was used to collect data and obtained data were analyzed using SPSS software and statistical analysis methods. The validity of a questionnaire designed was approved by the expert opinions and professors in the relevant organization. Cranach's alpha of the questionnaire was 78/0 that confirmed its reliability. Finally, the relationship between determined organizational factors and health administrative was approved and the effectiveness of each of these factors was identified using regression methods. | 2022-02-10T02:42:43.964Z |
111,883,169 | {
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"DOI": "10.1080/13574809.2015.1030997",
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} | Matthew Heins (2015) deserves a great deal of credit for providing a fresh perspective on the controversy between NewUrbanism and Landscape Urbanism that has so far generated more heat than light. As with so many such controversies, both sides seem to take special pains to conceal how much they have in common. Heins rightly emphasizes that both New Urbanism and Landscape Urbanism concentrate on re-forming suburban sprawl as the key issue for contemporary urban design; both movements see code, regulations and standards as the principal means for operating on a regional scale; and he provides a useful and perceptive list of projects that could serve as ‘common ground’ for the two movements. Indeed, his argument could be taken even further, at least from the perspective of history. New Urbanism and Landscape Urbanism both derive ultimately from Frederick Law Olmsted’s vision of urban expansion channelled into coherently and landscaped suburbs surrounded by a still-agrarian landscape. This nineteenth-century orchestration of density and openness has recently been celebrated in the monumental volume Paradise Planned: The Garden Suburb and the Modern City by Robert A.M. Stern, David Fishman and Jacob Tilove (2013). As they show, the garden suburb vision was supported by rail and streetcar technology, which relied on a walkable density at stops and along the lines, with an open landscape preserved between the lines extending out into the countryside. At the end of the nineteenth and the beginning of the twentieth centuries this ideal received strong support from Ebenezer Howard and the Garden City movement, that similarly sought to re-form growth at the edge of the metropolis into dense, walkable garden cities or suburbs surrounded by a perpetual greenbelt but linked to each other and to a central city by efficient rail lines. One might argue that New Urbanism and Landscape Urbanism are in their separate ways both attempting to recover the unity of the nineteenth-century Olmsted/Garden Suburb vision for the twenty-first centurymetropolis, with New Urbanists emphasizing (following Howard) the creation of walkable, well-defined towns at the edge of the metropolis, and Landscape Urbanists taking up Olmsted’s vision of an ‘open edge’ to the metropolis defined by landscape. Moreover, both are struggling with the impact of the automobile that permitted filling-in the open space between transit lines with low-density development, thus destroying the careful orchestration of density and openness on which both the Olmsted and the Garden City traditions depended. | 2022-02-10T03:51:47.153Z |
121,750,415 | {
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"DOI": "10.1117/12.877167",
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} | We have solved the well known and important problem of particle degeneracy for particle filters. Our filter is roughly seven orders of magnitude faster than standard particle filters for the same estimation accuracy. The new filter is four orders of magnitude faster per particle, and it requires roughly three orders of magnitude fewer particles to achieve the same accuracy as a standard particle filter. Typically we beat the EKF or UKF accuracy by approximately two orders of magnitude for difficult nonlinear problems. | 2022-12-17T12:25:26.890Z |
7,746,310 | {
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"DOI": "10.4197/Eng.15-1.9",
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} | The finite moving horizon ( MH) is proposed for the suboptimal decentralized linear quadratic problems. The technique of MH is based on a finite stage solution of the Riccati difference equation. Numerical results show that MH technique has fast computability properties. The proposed technique is tested with a numerical example. | 2022-02-13T08:43:27.081Z |
179,112,153 | {
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"DOI": "10.20396/RFE.V5I2.8635403",
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} | O presente estudo teve como objetivo analisar as publicacoes referentes a tematica “corpo”, tendo em vista os artigos da Revista Brasileira Ciencias do Esporte (RBCE) e Revista Movimento, no periodo de 1990 a 2010. Foram identificados 42 artigos e houve predominância da autoria individual. Podemos perceber que os artigos tem privilegiado as discussoes voltadas para a area pedagogica e discussoes teoricas do corpo partindo de uma visao historico-cultural. Notamos que ha uma concentracao regional no que tange as questoes sobre corpo nas regioes Sudeste e Sul, o que expressa a necessidade de expandir tal discussao para demais regioes. | 2022-01-24T20:48:48.255Z |
234,722,472 | {
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"DOI": "10.35418/2526-4117/v2n1a3",
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"url": "http://fpbjournal.com/fpbj/index.php/fpbj/article/download/68/25/"
} | Estimates of genetic parameters and repeatability coefficients in peach breeding are scarce. In view of this, the present study was carried out to estimate genetic parameters for plant and fruit traits and repeatability coefficients for fruit traits in S2 peach genotypes grown in a subtropical environment. A total of 434 individuals from 55 full-sib families of five populations were used in the study. The following plant traits were evaluated: trunk diameter at 10 cm above soil level (TD10), trunk diameter at 130 cm above soil level (TD130), plant height (PH), rate of budding on mixed branches (RB), rate of blind nodes on mixed branches (RBN), fruit number (FN) and harvest time (HT). In the fruit, the following traits were measured: weight (FW), diameter (FD), length (FL), diameter/length ratio (FD/FL), percentage of red in the epidermis (PRE), apex prominence (AP), suture line prominence (SLP), total soluble solids content (TSS), total titratable acidity (TTA) and TSS/TTA ratio (TSS/TTA). Repeated measures were performed for FD, FL, FD/FL, PRE, AP and SLP. Statistical analyses were run through the mixed model methodology. Genetic variability was detected for all traits. Individual narrowsense heritability values of moderate to high magnitude were found for the plant traits and of low to moderate magnitude for the fruit traits. Repeatability coefficients of moderate to high magnitude were obtained for the fruit traits. Except for the SLP trait, the evaluation of six fruits per plant revealed coefficients of determination higher than 80%, indicating high accuracy. | 2022-05-31T02:11:55.468Z |
129,015,798 | {
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"DOI": "10.1080/17445647.2013.866911",
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"url": "https://www.tandfonline.com/doi/pdf/10.1080/17445647.2013.866911?needAccess=true"
} | The accompanying Main Map shows forest vulnerability zones calculated for the Czech Republic, covering a total area of almost 79,000 km2. Calculating forest vulnerability zones over such a large area requires a unique approach due to its complexity. The map includes additional information on forest areas and topography. The model of forest vulnerability zones (FVZ) constitutes an alternative to existing zones of forest health hazard caused by emissions. It was created based on subjective classification of existing incidence of damage in forests. Moreover, the model of forest vulnerability zones estimates the risk of forest health degradation caused by abiotic factors. | 2022-09-05T01:15:07.810Z |
4,602,156 | {
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} | Background:In the emergent setting, most paraesophageal hernia (PEH) repairs are done by laparotomy with adjunct gastropexy or gastrostomy tube (GT) placement. This adjunct to the repair can be performed expeditiously by a laparoscopic approach by utilizing T-fasteners. We present our case series of patients with PEHs and acute gastric volvulus that were managed with laparoscopy and how patient characteristics can influence the repair technique. Methods:Patients with high operative risk who underwent laparoscopic hiatal hernia repair with adjunct T-fastener gastropexy in the emergent setting between July 2014 and July 2016 were included in this study. Results:Thirteen patients underwent successful PEH repair and all were classified as urgent/emergent upon admission. In total, 30.7% were performed laparoscopically. The median patient age was 84 years. A laparoscopic GT or gastropexy was performed for fixation of the stomach. Crural closure by an anterior cruroplasty was performed in all patients. There were no mortalities. One patient required conversion of gastropexy into a GT given symptoms of dysphagia. Prolonged length of stay was related to postdischarge institutionalization. All patients remained free of obstructive symptoms. Conclusions:Laparoscopic PEH repair with adjunct gastropexy or GT placement should be considered in emergent cases for elderly patients with predominately obstructive symptoms. Laparoscopy for PEH repair is challenging and requires technical skills. T-fastener gastropexy or GT placement is safe, simple, and obviates the need for intracorporeal suturing. It also may be used to improve physician comfort with laparoscopy and to expedite the repair in this high-risk population. | 2022-09-11T23:31:08.599Z |
1,559,062 | {
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"DOI": "10.6028/jres.113.027",
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"url": "https://doi.org/10.6028/jres.113.027"
} | To detect the growth in lesions, it is necessary to ensure that the apparent changes in size are above the noise floor of the system. By introducing a fiducial reference, it may be possible to detect smaller changes in lesion size more reliably. We suspend three precision spheres with a precision structure built from pieces from a popular children’s building toy. We measure the distances between the centroids of the structures three ways; namely, with a high-precision mechanical method, micro computerized tomography, and medical computerized tomography. The three methods are in agreement, and also agree with the design values for the structure. It is also possible to pick a threshold so that the three spheres have their nominal volumes in the medical computerized tomography images. The use of volumetric measures allows the determination of lengths to much less than the voxel size using materials which have x-ray properties within the range of the human body. A suitable structure may be built with a very small parts cost. | 2022-10-07T00:49:10.047Z |
107,842,529 | {
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"DOI": "10.1201/b17395-170",
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},
"license": "CCBYNC",
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"url": "https://napier-repository.worktribe.com/file/174416/1/Winkler%20Springs%20%28p-y%20Curves%29%20For%20Liquefied%20Soil%20From%20Element%20Tests"
} | In practice, piles are most often modelled as "Beams on Non-Linear Winkler Foundation" (also known as "p-y spring" approach) where the soil is idealised as p-y springs. These p-y springs are obtained through semi-empirical approach using element test results of the soil. For liquefied soil, a reduction factor (often termed as p-multiplier approach) is applied on a standard p-y curve for the non-liquefied condition to obtain the p-y curve liquefied soil condition. This paper presents a methodology to obtain p-y curves for liquefied soil based on element testing of liquefied soil considering physically plausible mechanisms. Validation of the proposed p-y curves is carried out through the back analysis of physical model tests. | 2022-10-21T00:45:15.944Z |
95,213,538 | {
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"DOI": "10.1590/S0103-90161996000100006",
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} | The purpose of this work was to evaluate the effect of exchangeable sodium percentage and electrolite concentration of percolating water, on the hydraulic conductivity of a Noncalcic Brown Soil of the region of the River Salitre-Ba, Brazil. The experiment was conducted under laboratory conditions and consisted of the determination of the saturated hydraulic conductivity using leaching solutions with different electrolite concentrations. In addition, the eletrical conductivity of the percolate and sodium exchangeable concentration, were measured before and after percolation of the solution. Using Richards pressure-membrane apparatus, contents of sodium dislocated were measured at different tensions. A low correlation between the hydraulic conductivity and the exchangeable sodium percentage levels was found. Application of calcium sulfate solution presented a beneficial effect on the saturated hydraulic conductivity, except when irreversible processes of mineral dissolution occurred. This effect has been associated to pH or carbonate content in the percolating solution. | 2022-11-11T07:56:53.593Z |
9,157,456 | {
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"DOI": "10.4049/jimmunol.174.10.6299",
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"status": "BRONZE",
"url": "http://www.jimmunol.org/content/174/10/6299.full.pdf"
} | Neisseria meningitidis (meningococcus) is an important cause of meningitis and sepsis. Currently, there is no effective vaccine against serogroup B meningococcal infection. Host defense against neisseriae requires the complement system (C) as indicated by the fact that individuals deficient in properdin or late C components (C6-9) have an increased susceptibility to recurrent neisserial infections. Because the classical pathway (CP) is required to initiate efficient complement activation on neisseriae, meningococci should be able to evade it to cause disease. To test this hypothesis, we studied the interactions of meningococci with the major CP inhibitor C4b-binding protein (C4bp). We tested C4bp binding to wild-type group B meningococcus strain (H44/76) and to 11 isogenic mutants thereof that differed in capsule expression, lipo-oligosaccharide sialylation, and/or expression of either porin (Por) A or PorB3. All strains expressing PorA bound radiolabeled C4bp, whereas the strains lacking PorA bound significantly less C4bp. Increased binding was observed under hypotonic conditions. Deleting PorB3 did not influence C4bp binding, but the presence of polysialic acid capsule reduced C4bp binding by 50%. Bound C4bp remained functionally active in that it promoted the inactivation of C4b by factor I. PorA-expressing strains were also more resistant to C lysis than PorA-negative strains in a serum bactericidal assay. Binding of C4bp thus helps Neisseria meningitidis to escape CP complement activation. | 2022-12-13T10:08:41.769Z |
86,050,105 | {
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"DOI": "10.1080/11250003.2012.758784",
"MAG": "2156988140",
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} | Abstract Breeding success was investigated in a mixed colony of three species of Ardeidae (Black-crowned Night Heron, Nycticorax nycticorax; Little Egret, Egretta garzetta; and Cattle Egret, Bubulcus ibis) in the Karfestan colony, south Caspian Sea, during the 2006 breeding season. Black-crowned Night Herons occupied higher locations for nesting (4.39 ± 1.44 m) than both Little Egrets (3.07 ± 1 m) and Cattle Egrets (2.8 ± 0.84 m). Clutch size appeared to be independent of the height of the nest from the ground in all species. Mean breeding success was 0.82 ± 0.24, 0.80 ± 0.16 and 0.77 ± 0.17 in the Black-crowned Night Heron, Little Egret and Cattle Egret respectively. Overall breeding success did not vary significantly among the three species. Fledging success and overall breeding success were associated with nest height in the Black-crowned Night Heron, with a tendency for the higher nests to be more successful. Nest height was also correlated with fledging success in the Cattle Egret but had no effect on breeding success in the Little Egret. | 2022-12-14T22:49:02.605Z |
154,790,671 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.2307/1973585",
"MAG": "2093237345",
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} | International Issues Trade Theory and the Less Developed Countries, David Greenaway and Chris Milner Trade Strategies and Industrialization in LDCs, Colin Kirkpatrick Multinational Enterprises in LDCs, Mark Casson Robert Pearce Macroeconomic Problems Poverty, Inequality and Development, Arne Bigsten Inflation and Stabilisation Policy in LDCs, Colin Kirkpatrick and Frederick Nison Factor Markets in LDCs The Labour Market and Human Capital in LDCs, Albert Berry Technology Choice and Factor Proportions Problems in LDCs, Henry Bruton The Public Sector and Development Taxation and Development, Norman Gemmell Project Appraisal Techniques, Ivy Papps The Rural Sector Agriculture and Economic Development, Subrata Ghatak. | 2022-12-19T01:04:10.898Z |
195,857,956 | {
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"DOI": "10.1109/IAS.2000.880974",
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} | The paper deals with the identification of parameters of a two-axis linear synchronous reluctance motor (LSRM) dynamic model. The model parameters are identified by experiments performed on an LSRM using a controlled voltage source inverter. The current dependent direct- and quadrature axis inductances are identified by experiments and calculated by the finite element method. The calculated inductances are compared with the inductances identified by experiments. As the translation range of the tested LSRM is limited, the proposed parameter identification procedure has been verified indirectly through the comparison of simulation and experimental results in the case of kinematic control. Compared are the reference and the actual position, speed, current and voltage trajectories obtained by experiment and by simulation. The agreement of the results is good. | 2022-12-19T05:45:54.721Z |
250,894,759 | {
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"DOI": "10.1088/0953-8984/14/13/319",
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},
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} | We study the energy and intensity dependence of the dephasing time T2 of the polarization in CuCl inside an excitonic resonance by a femtosecond four-wave mixing technique at 5 K. We first compare results obtained on bulk material and on epitaxial films of different thicknesses for a backward-scattering configuration. This configuration is most sensitive to the region close to the surface of the samples. In bulk material, the coherence properties of the polarization are mainly limited by recombination processes and scattering with acoustic phonons while they are in addition influenced by scattering with impurities and/or imperfections in the epitaxial films. In these films, in a transmission configuration, the polarization dephases less rapidly than it appears in retrodiffusion, indicating the importance of surface recombination processes and of the polariton propagation. | 2022-12-19T15:15:58.880Z |
249,384,147 | {
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"DOI": "10.34067/kid.0001062022",
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},
"license": null,
"status": "GOLD",
"url": "https://kidney360.asnjournals.org/content/kidney360/3/8/1323.full.pdf"
} | Background
In patients without COVID-19, dysnatremia is associated with mortality. These relationships are not well established in patients with COVID-19. We tested the hypotheses that patients with COVID-19 were more likely to have dysnatremia than those without COVID-19 and that, among those with COVID-19, dysnatremia is associated with mortality.
Methods
We conducted a retrospective observational study of patients admitted to a tertiary care center in the Bronx, New York, during the COVID-19 surge from March 11 to April 26, 2020. Using multinomial logistic regression models, we compared the prevalence of hypernatremia (serum sodium ≥150 mEq/L) and hyponatremia (serum sodium <130 mEq/L) on admission between patients with and without COVID-19. Among patients with COVID-19, we used Cox proportional hazards models to examine the association of dysnatremia with mortality.
Results
Compared with those without COVID-19 (n=1265), patients with COVID-19 (n=3345) had a higher prevalence of hypernatremia (7% versus 4%, P<0.001) and hyponatremia (7% versus 6%, P=0.04). In adjusted models, COVID-19-positive patients had a higher likelihood of having hypernatremia (adjusted odds ratio=1.87, 95% CI, 1.3 to 2.57, P=0.001) compared with COVID-19-negative patients, whereas the association between hyponatremia and COVID-19 status was no longer significant (P=0.06). Among patients with COVID-19, 775 (23%) died after a median follow-up of 17 days (IQR 7-27 days). Among nonsurvivors, 15% had hypernatremia and 8% had hyponatremia on admission. Hypernatremia was associated with a higher risk of mortality (adjusted hazard ratio=1.28, 95% CI, 1.01 to 1.63, P=0.04) compared with patients with eunatremia.
Conclusions
In patients hospitalized during the spring 2020 COVID-19 surge, COVID-19 status was associated with hypernatremia on admission. Among patients with COVID-19, hypernatremia was associated with higher mortality. Hypernatremia may be a potential prognostic marker for mortality in COVID-19 patients. | 2022-12-21T14:11:22.911Z |
204,783,795 | {
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"ArXiv": null,
"DOI": "10.1063/1674-0068/cjcp1904065",
"MAG": "2999378226",
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} | We performed high-level ab initio calculations on electronic structure of NaK. The potential energy curves (PECs) of 10 Λ-S states correlated with the three lowest dissociation limits have been calculated. On the basis of the calculated PECs, the spectroscopic constants of the bound??-S states are obtained, which are in good agreement with experimental results. The maximum vibrational quantum numbers of the singlet ground state X1Σ+ and the triplet ground state a3Σ+ have been analyzed with the semiclassical scattering theory. Transition properties including transition dipole moments, Franck-Condon factors, and radiative lifetimes have been investigated. The research results indicate that such calculations can provide fairly reliable estimation of parameters for the ultracold alkali diatomic molecular experiment. | 2022-09-28T05:55:52.625Z |
9,506,123 | {
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"DOI": "10.1001/JAMA.1988.03720020027031",
"MAG": "2074780401",
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} | Twenty-one percent of 292 patients with untreated borderline hypertension (clinic diastolic blood pressures persistently between 90 and 104 mm Hg) were found to have normal daytime ambulatory pressures (defined from a population of normotensive subjects). These patients were defined as having "white coat" hypertension, and they were more likely to be female and younger, to weigh less, and to be more recently diagnosed than patients whose pressure was elevated both in the clinic and during ambulatory monitoring. Patients with white coat hypertension did not show a generalized increase of blood pressure lability, nor an exaggerated pressor response while at work. The phenomenon is more pronounced when blood pressure is measured by a physician than by a technician. In such patients, the pressor response may be relatively specific to the physician's office and lead to significant misclassification of hypertension. | 2022-12-26T19:11:55.549Z |
86,543,673 | {
"externalids": {
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"DOI": "10.1034/J.1600-0587.2001.240302.X",
"MAG": "2090728056",
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} | In most groups of organisms, the species richness decreases from the tropics to the poles. The mechanisms causing this latitudinal diversity gradient are still controversial. We present data from a comprehensive weighted meta-analysis on the strength of the latitudinal gradient in relation to body size. We sampled literature data on the correlation between species richness and latitude for a variety of organisms, ranging from trees to protozoa. In addition, own data on the presence of large-scale diversity patterns for diatoms were included, both for local and regional species richness. The strength of the latitudinal gradient was positively correlated to the size of the organisms. Strongest decreases of species richness to the poles was found for large organisms like trees and vertebrates, whereas meiofauna, protozoa and diatoms showed weak or no correlations between species richness and latitude. These results imply that latitudinal gradients are shaped by non-equilibrium (regional) processes and are persistent under conditions of dispersal limitation. | 2022-12-29T18:39:18.192Z |
12,402,832 | {
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"ArXiv": null,
"DOI": "10.1210/JC.2005-2679",
"MAG": "2117507851",
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"url": null
} | CONTEXT
Cannabinoid CB(1) receptor blockade decreases weight and hyperinsulinemia in obese animals and humans in a way greatly independent from food intake.
OBJECTIVE
The objective of this study was to investigate the regulation and function of the endocannabinoid system in adipocytes and pancreatic beta-cells.
DESIGN, SETTING, AND PATIENTS
Mouse 3T3-F442A adipocytes and rat insulinoma RIN-m5F beta-cells, pancreas and fat from mice with diet-induced obesity, visceral and sc fat from patients with body mass index equal to or greater than 30 kg/m(2), and serum from normoglycemic and type 2 diabetes patients were studied.
MAIN OUTCOME MEASURE
Endocannabinoid enzyme and adipocyte protein expression, and endocannabinoid and insulin levels were measured.
RESULTS
Endocannabinoids are present in adipocytes with levels peaking before differentiation, and in RIN-m5F beta-cells, where they are under the negative control of insulin. Chronic treatment of adipocytes with insulin is accompanied by permanently elevated endocannabinoid signaling, whereas culturing of RIN-m5F beta-cells in high glucose transforms insulin down-regulation of endocannabinoid levels into up-regulation. Epididymal fat and pancreas from mice with diet-induced obesity contain higher endocannabinoid levels than lean mice. Patients with obesity or hyperglycemia caused by type 2 diabetes exhibit higher concentrations of endocannabinoids in visceral fat or serum, respectively, than the corresponding controls. CB(1) receptor stimulation increases lipid droplets and decreases adiponectin expression in adipocytes, and it increases intracellular calcium and insulin release in RIN-m5F beta-cells kept in high glucose.
CONCLUSIONS
Peripheral endocannabinoid overactivity might explain why CB(1) blockers cause weight-loss independent reduction of lipogenesis, of hypoadiponectinemia, and of hyperinsulinemia in obese animals and humans. | 2022-12-31T06:16:33.697Z |
229,461,444 | {
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"DOI": "10.1111/1748-5967.12488",
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} | Overwintering aggregations of Halyomorpha halys (Hemiptera: Pentatomidae) in human‐made structures cause nuisance problems and enable this pest to invade new countries. Therefore, understanding the overwintering aggregation behaviors of H. halys would serve as a basis to mitigate these pest problems. In this study, we induced adult H. halys to exhibit overwintering behaviors in laboratory conditions and assessed how this pest responded to a potential overwintering structure and settled in the structure over 24 hours. A potential overwintering micro‐habitat was provided to H. halys in reproductive diapause by establishing a 5‐mm gap between two acrylic panels facing each other. This experimental arena was kept in a cage at 11°C, 12:12 (L:D), and 30% relative humidity (RH). A total of 50 adults (sex ratio = 1:1) was released into the cage for each replication. First, more females than males crawled into the 5‐mm gap and settled in the experimental arena: the proportion of females having settled in the arena was 68.64 ± 3.03%. Second, when H. halys were settling in the arena, they did not significantly synchronize their dorsal or ventral side directions with other individuals. Third, H. halys tended to settle in the lower section of the experimental arena. Finally, 69.1 ± 3.9% of overwintering H. halys were found to settle solitarily, not touching other individuals in the experimental arena. Further studies are warranted to validate our results in semi‐field conditions in which more H. halys are released and monitored for longer times. | 2022-12-18T13:48:58.520Z |
245,387,282 | {
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"DOI": "10.3389/fphar.2021.769793",
"MAG": null,
"PubMedCentral": "8735858"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fphar.2021.769793/pdf"
} | Background and Aims: Surgery remains the major available strategy in inflammatory bowel disease (IBD) fibrotic strictures because no available drugs have sufficient prevention and treatment in this complication. This study aimed to evaluate the efficacy of the total flavone of Abelmoschus manihot L. Medic (TFA) on the development of colonic fibrosis in mice and its possible mechanism. Methods: The 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced chronic colonic inflammation-associated fibrosis mice were used to evaluate anti-fibrosis of TFA using macroscopic, histological, immunohistochemical analyses, ELISA, Masson staining, Verhoeff’s von Gieson staining, transcription-quantitative polymerase chain reaction, and immunoblot analysis. Results: Oral administration of TFA attenuated body weight loss, reduced colon length shortening, lowered the morphological damage index score, and notably ameliorated the inflammatory response. TFA downregulated proinflammatory cytokines IL-6, IL-17, TNF-α, IFN-γ productions, and increased the levels of anti-inflammatory cytokine IL-10 and TGF-β. The histological severity of the colonic fibrosis was also notably improved by the TFA treatment and associated with a significant reduction in the colonic expression of col1a2, col3a2, and hydroxyproline. TFA inhibits α-SMA, TGF-β, vimentin, TIMP-1 expression, increasing MMPs, thereby inhibiting activated intestinal mesenchymal cells and extracellular matrix (ECM) deposition. Conclusion: Together, we herein provide the evidence to support that TFA may restore the imbalance of Th17/Treg and decrease the generation of ECM. This may be a potential mechanism by which TFA protects the intestine under inflammatory conditions and acts as a therapeutic agent for the treatment of intestinal fibrosis in Crohn’s disease. | 2022-12-25T22:56:13.523Z |
161,249,232 | {
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"DOI": "10.21501/16920945.1231",
"MAG": "1566697925",
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},
"license": "CCBYNCND",
"status": "GOLD",
"url": "http://www.funlam.edu.co/revistas/index.php/poiesis/article/download/1231/1121"
} | Las comunidades son complejas, tienen un sistema social de raiz que se hace diferenciable en el seno de una sociedad, en el que se construyen situaciones, caracteristicas e intereses compartidos por sus miembros. Los actores de estos escenarios sociales desarrollan relaciones y lazos horizontales, se generan los vinculos interpersonales, la cohesion social y los sentidos de pertenencia. Lo que no entiendo, y me crea complejidad de comprension, es ?como se construyen esas percepciones sociales, esas actitudes, esas creencias y la forma tan enmaranada de interpretar esa realidad? | 2022-01-27T13:12:04.114Z |
54,171,858 | {
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"DOI": "10.1051/MATECCONF/20178703001",
"MAG": "2566922734",
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} | Bubble flow reactors (BFR) are commonly used for various industrial processes in the field of oil and gas production, pharmaceutical industries, biochemical and environmental engineering etc. The operation and performance of these reactors rely heavily on a range of hydrodynamic parameters; prominent among them are geometric configurations including gas injection geometry, operating conditions, mass transfer etc. A huge body of literature is available to describe the optimum design and performance of bubbly flow reactors with conventional bubble injection. Attempts were made to modify gas injection for improved efficiency of BFR's. However, here instead of modifying the geometry of the gas injection, an attempt has been made to generate swirl bubbles for gaining larger mass transfer between gas and liquid. Here an exceptionally well thought strategies have been used in our numerical simulations towards the design of swirl injection mechanism, whose paramount aspect is to inhibit the rotary liquid motion but facilitates the swirl movement for bubbles in nearly stationary liquid. Our comprehension here is that the swirl motion can strongly affect the performance of bubbly reactor by identifying the changes in hydrodynamic parameters as compared to the conventional bubbly flows. In order to achieve this bubbly flow, an experimental setup has been designed as well as computational fluid dynamic (CFD) code was used with to highlight a provision of swirl bubble injection by rotating the sparger plate. | 2022-02-11T21:15:46.717Z |
70,438,833 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.5694/j.1326-5377.1959.tb89286.x",
"MAG": "1743126302",
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},
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"status": "GREEN",
"url": "https://www.erudit.org/fr/revues/ri/1953-v8-n2-ri01200/1022958ar.pdf"
} | Rehabilitation in Industry. Edited by Donald A. Covait. M.D. “Modern Monographs in Industrial Medicine.” Editor‐in‐Chief, Anthony J. Lanza, M.D.; Consulting Editor, Richard H. Orr, M.D.; 1958. New York and London: Grune and Stratton, Inc. 8½“ × 5¼“, pp. 168, with many illustrations. Price: $6.00. | 2022-07-08T02:08:18.981Z |
237,899,013 | {
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"ArXiv": null,
"DOI": "10.52494/aqdl4117",
"MAG": "3182162591",
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},
"license": null,
"status": "BRONZE",
"url": "https://mjpharm.org/wp-content/uploads/2021/07/2021-Malaysian-Journal-of-Pharmacy-7-1-34-42.pdf"
} | Anti-peptic ulcer drugs (APUDs) such as proton pump inhibitors (PPI), H2 receptor antagonists (H2A), antacids are widely prescribed. This study is aimed to describe the utilisation pattern of APUDs based on WHO Defined Daily Dose (DDD) and identify most commonly used APUD in the selected hospital. A retrospective study was carried out in outpatient of the selected hospital for year 2017. Sample size was calculated using Raosoft. DDD of APUDs and direct drug cost were calculated. Data were collected through electronic medical record by retrieving patients’ registration number. Inclusion criteria were patients above 18 years old and APUDs prescribed for gastrointestinal related indications. A total of 160 prescriptions were randomly selected for data analysis. Based on the DDD calculated, Rabeprazole 20mg was most prescribed drug among PPI (n=33), while Maalox is most prescribed drug among the antacids (n=23). Based on the DDD calculated, Pantoprazole 20mg recorded highest rates per user per day about 1.26 DDD / user / day while antacids, Actal reported highest usage rate with 7.11 DDD / user / day. Besides, there are 5.4 days supplied per user for this drug. Dexlansoprazole 60mg is the most expensive drug among all the PPI listed in hospital formulary. It has 18.5 days supplied/user, which is the second shortest duration of treatment among all the other PPIs. In contrast, omeprazole 20mg is the lowest cost PPI but the duration supplied per user is longer resulting in higher total cost of therapy. In conclusion, PPIs were the most commonly prescribed. | 2022-09-08T20:58:34.261Z |
207,125,565 | {
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"ArXiv": null,
"DOI": "10.1021/ja802700z",
"MAG": "1978002986",
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} | The first enantioselective total synthesis of the rearranged Securinega alkaloid (-)-secu'amamine A is reported starting from D-proline as the source of absolute chirality. The synthesis requires 15 steps starting from D-proline-derived N-trityl aldehyde 11 and proceeds in approximately 9% overall yield. Key steps include a stereoselective conjugate addition of pyrrolidino enedione 19 to afford indolizidine 24 as the major product and cyclization/lactonization of diketoester 25 to produce tetracycle 26. In addition, 1H NMR NOE studies and X-ray analysis on the synthetic alkaloid have established that the indolizidine moiety is trans-fused. | 2022-09-15T03:26:36.766Z |
56,282,761 | {
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"DOI": "10.5194/ISPRS-ARCHIVES-XLI-B3-481-2016",
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"status": null,
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} | Abstract. The need for reliable systems for capturing precise detail in tunnels has increased as the number of tunnels (e.g., for cars and trucks, trains, subways, mining and other infrastructure) has increased and the age of these structures and, subsequent, deterioration has introduced structural degradations and eventual failures. Due to the hostile environments encountered in tunnels, mobile mapping systems are plagued with various problems such as loss of GNSS signals, drift of inertial measurements systems, low lighting conditions, dust and poor surface textures for feature identification and extraction. A tunnel mapping system using alternate sensors and algorithms that can deliver precise coordinates and feature attributes from surfaces along the entire tunnel path is presented. This system employs image bridging or visual odometry to estimate precise sensor positions and orientations. The fundamental concept is the use of image sequences to geometrically extend the control information in the absence of absolute positioning data sources. This is a non-trivial problem due to changes in scale, perceived resolution, image contrast and lack of salient features. The sensors employed include forward-looking high resolution digital frame cameras coupled with auxiliary light sources. In addition, a high frequency lidar system and a thermal imager are included to offer three dimensional point clouds of the tunnel walls along with thermal images for moisture detection. The mobile mapping system is equipped with an array of 16 cameras and light sources to capture the tunnel walls. Continuous images are produced using a semi-automated mosaicking process. Results of preliminary experimentation are presented to demonstrate the effectiveness of the system for the generation of seamless precise tunnel maps. | 2022-10-28T18:19:00.222Z |
237,795,486 | {
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"ArXiv": null,
"DOI": "10.3991/IJET.V16I13.22261",
"MAG": "3179566899",
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},
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} | Despite the massive number of enrollments in MOOC (Massive Open Online Course) platforms, dropout rates are very high. This problem can be due to several factors: Social, pedagogical, prior knowledge as well as a demotivation. To deal with this type of problems, we have designed an adaptive cMOOC (Connectivist MOOC) platform for each registered learner’s profile.
From the first human-machine interaction, the process adapts the learner's need according to a pre-established model. It is based on the processing of statistical data collected by correspondence analysis and regression algorithms. Each generated learner’s profile will provide an adaptive navigation and pedagogical activities. The intelligent system presented in this work will be able to classify learners according to their preferences and learning styles. | 2022-11-25T00:20:05.848Z |
73,437,005 | {
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"ArXiv": null,
"DOI": "10.1111/scd.12368",
"MAG": "2914468646",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc6402806?pdf=render"
} | OBJECTIVE
Dentinogenesis Imperfecta (DI) forms a group of dental abnormalities frequently found associated with Osteogenesis Imperfecta (OI), a hereditary disease characterized by bone fragility. The objectives of this study were to quantify the dental caries prevalence and experience among different OI-types in the sample population and quantify how much these values change for the subset with DI.
METHODS
To determine which clinical characteristics were associated with increased Caries Prevalence and Experience (CPE) in patients with OI, the adjusted DFT scores were used to account for frequent hypodontia, impacted teeth and retained teeth in OI population. For each variable measured, frequency distributions, means, proportions and standard deviations were generated. Groups means were analyzed by the unpaired t-test or ANOVA as appropriate. For multivariate analysis, subjects with caries experience of zero were compared with those with caries experience greater than zero using logistic regression.
RESULTS
The stepwise regression analysis while controlling for all other variables demonstrated the presence of DI (OR 2.43; CI 1.37-4.32; P = 0.002) as the significant independent predictor of CPE in the final model.
CONCLUSION
This study found no evidence that CPE of OI subjects differs between the types of OI. The presence of DI when controlled for other factors was found to be the significant predictor of CPE. | 2022-12-09T09:23:18.377Z |
1,585,884 | {
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICRE.2003.1232762",
"MAG": "2147858218",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
} | We report our experience of product-line development for a wide variety of e-Government applications based on multilayered frameworks. The key contributions include the modeling a variety of requirements for e-Government applications, software architecture for multiple product-lines framework anticipating the variety, scenario-and-event-based patterns for composing the frameworks and components, and the statistical evaluation of the experience. | 2022-12-11T10:40:59.223Z |
237,205,895 | {
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3465631.3465655",
"MAG": null,
"PubMedCentral": null
},
"license": null,
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"url": null
} | NOTICE OF RETRACTION: While investigating potential publication-related misconduct in connection with the ICIMTech 2021 Conference Proceedings, serious concerns were raised that cast doubt on the integrity of the peer-review process and all papers published in the Proceedings of this Conference. The integrity of the entire Conference has been called into question. As a result, of its investigation, ACM has decided to retract the Entire Conference Proceedings and all related papers from the ACM Digital Library. None of the papers from this Proceeding should be cited in the literature because of the questionable integrity of the peer review process for this Conference. | 2022-12-14T11:53:09.847Z |
33,610,217 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1159/000474420",
"MAG": "1464415450",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
} | OBJECTIVES
To review anatomical and histological findings in 105 vanishing testes.
METHODS
Records of 2,509 boys with 3,064 cryptorchid testes treated at our hospital between 1969 and 1995 were reviewed.
RESULTS
691 (23%) testes were clinically impalpable. Exploration in 691 impalpable testes revealed absent testis in 144 (21%). In 39 (27%) of the 144 absent testes, there was complete agenesis of testis along with the epididymis and vas deferens whereas 105 (73%) were associated with blind-ending cord structures-the vanishing testis. The site of blind-ending cord structures in 105 vanishing testes was intra-abdominal in 22 (21%), inguinal canal in 62 (59%), superficial inguinal ring in 19 (18%) and scrotum in 2 (2%). Histological information was available in 47 vanishing testes and revealed vas, epididymis, or both in 32 (68%), fibrous/vascular tissue in 11 (23%) and testicular cords in 4 (9%). Dystrophic calcification and/or haemosiderin were present in 7 (15%).
CONCLUSIONS
Our data show that the incidence of vanishing testis in boys with non-palpable testes is over twice the incidence of testicular agenesis. The most common site of blind-ending cord structures is distal to the internal inguinal ring. The finding of viable testicular tissue at the end of the attenuated cord structures in 4 of our patients, and also reported in other series, suggests that inguinal exploration should be carried out in all patients who on laparoscopy are found to have cord structures entering the internal ring. | 2022-12-16T06:55:48.946Z |
6,491,834 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1083/JCB.23.2.339",
"MAG": "2062480161",
"PubMedCentral": "2106531"
},
"license": null,
"status": null,
"url": null
} | The development of basal bodies and flagella in the water mold Allomyces arbusculus has been studied with the electron microscope. A small pre-existing centriole, about 160 mµ in length, was found in an inpocketing of the nuclear membrane in the vegetative hypha. Thus, formation of a basal body does not occur de novo. When the hyphal tip started to differentiate into gametangia, the centrioles were found to exist in pairs. One of the members of the pair then grew distally to more than three times its original length, whereas the other remained the same size. The larger centriole would correspond to the basal body of a future gamete. Gametogenesis was usually induced by transferring a "ripe" culture to distilled water. Shortly after this was done, a few vesicles were pinched off from the cell membrane of the gametangium and came in contact with the basal body. Apparently, they fused and formed a large primary vesicle. The flagellum then started to grow by invaginating into it. Flagellar fibers were evident from the very beginning. As the flagellum grew so did the vesicle by fusion with secondary vesicles, thus coming to form the flagellar sheath. The different stages of flagellar morphogenesis are described and the possible interrelationships with other processes are discussed. | 2022-12-19T07:13:41.684Z |
230,631,107 | {
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"DOI": "10.1093/oso/9780198866695.003.0007",
"MAG": "3111919729",
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} | The chapter contributes to the development of a pluralistic conception of moral philosophy consisting of a diversity of descriptive activities by exploring one example of how to combine an understanding of the particulars of moral life with the more general and abstract insights traditionally developed in moral philosophy, namely via moral philosophy’s engagement with literature. The chapter is motivated by the argument that the irreducible role of the particular in moral life raises a demand for moral philosophy to interact with other disciplines which may serve as sources of knowledge about the particularities of moral life. It is argued that engagement with literature offers us knowledge by acquaintance and possibilities of moral cultivation, and that literature can be a suitable partner for moral philosophy in three activities that differ from the development of moral theories: namely in the exploration, the critique, and the development of moral life. The last type of activity, where literature is a partner for moral philosophy in initiating forms of moral change, is given special attention, and it is shown that this is an integrated part of moral philosophy, even if it is currently underexplored. | 2022-01-27T01:57:06.229Z |
145,186,607 | {
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"ArXiv": null,
"DOI": "10.1080/00220973.1970.11011226",
"MAG": "2079149015",
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},
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} | Data from 484 students out of a Hawaiian high school graduating class of 643 were used in a study of post-high school destinations. of these 643 students, 360 were found to have selected academic destinations. They were going either to universities, a regional 2-year branch of the state university, 4-year colleges, junior colleges, or technical schools. A factor analysis of ten variables consisting of teachers’ ratings of school related behavior, verbal (V) and quantitative (Q) School and College Abilities Tests (SCAT) scores, and rank in graduating class (R) revealed two factors: “g” a general intellective factor (SCAT Q and V) and school skills (teachers’ ratings and R). In general the institutions of high academic quality attracted students who were significantly higher on the variables of both factors. Variation from this pattern of choice was discussed in terms of ego self-direction and social control as it affected mobility away from the island location. | 2022-02-09T06:36:12.090Z |
250,055,867 | {
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"ArXiv": null,
"DOI": "10.2173/bow-on.100165",
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},
"license": null,
"status": "BRONZE",
"url": "https://static.birdsoftheworld.org/on165_white-browed_shrike-babbler.pdf"
} | Voice has already been analyzed in Rheindt & Eaton (2009), and was part of the evidence to split this complex as four BSC species. If we score vocal differences based on the measurements of voice (Table 3 p36, based on 30 recordings over 8 races, which is quite low), by applying Tobias criteria, we get: * ripleyi: vs validirostris: score 2 based on longer intra-motif breaks, but score 0 vs two other groups. * annamensis: shorter intra-motif breaks vs. aeralatus, but as this is part of group 'Blyth's', comparison with overall group gives score 0. Score vs. ripleyi about 1 and vs. flaviscapis score 0. * flaviscapis vs. Blyth's group: score 0 Considering the limited number of samples, the wide variation of measurement results within recordings of the same race, and the minimal differences identified, the stated conclusions on vocal differences are rather weakly supported by data and, at least within the framework of quantification by application of Tobias criteria, vocal differences rather fall in the category 'minor'. | 2022-07-04T20:19:09.835Z |
95,369,312 | {
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"DOI": "10.1002/1522-2675(20011017)84:10<3057::AID-HLCA3057>3.0.CO;2-5",
"MAG": "2029179399",
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},
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} | At pH 2, the rate constant of hydrolysis of tris(tetraethylammonium) pentacyanoperoxynitritocobaltate(III) in H2O is 9.6×10−6 s−1. In the absence of any light, ONOO− is not replaced by H2O and isomerizes within the coordination sphere to NO3−. The novel complex [Co(CN)5NO3]3− released NO3− slowly, as detected by ion chromatography. At pH 6, no hydrolysis is observed. Direct photolysis, both at pH 2 and pH 6, of tris(tetraethylammonium) pentacyanoperoxynitritocobaltate(III) by irradiation (YAG laser) at 355 nm destroys the coordinated ONOO− and releases NO2., which hydrolyzes to NO3− and NO2−. We also measured the 59Co-NMR spectra of [Co(CN)5OONO]3− and [Co(CN)5H2O]2−; the chemical shifts correspond very well to those predicted and are in agreement with the expected contribution to the ligand field by H2O and ONOO−. | 2022-09-14T13:41:23.422Z |
22,408,120 | {
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"DOI": "10.1371/journal.pone.0134454",
"MAG": "1901521400",
"PubMedCentral": "4537301"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134454&type=printable"
} | Wikipedia has quickly become one of the most frequently accessed encyclopedic references, despite the ease with which content can be changed and the potential for ‘edit wars’ surrounding controversial topics. Little is known about how this potential for controversy affects the accuracy and stability of information on scientific topics, especially those with associated political controversy. Here we present an analysis of the Wikipedia edit histories for seven scientific articles and show that topics we consider politically but not scientifically “controversial” (such as evolution and global warming) experience more frequent edits with more words changed per day than pages we consider “noncontroversial” (such as the standard model in physics or heliocentrism). For example, over the period we analyzed, the global warming page was edited on average (geometric mean ±SD) 1.9±2.7 times resulting in 110.9±10.3 words changed per day, while the standard model in physics was only edited 0.2±1.4 times resulting in 9.4±5.0 words changed per day. The high rate of change observed in these pages makes it difficult for experts to monitor accuracy and contribute time-consuming corrections, to the possible detriment of scientific accuracy. As our society turns to Wikipedia as a primary source of scientific information, it is vital we read it critically and with the understanding that the content is dynamic and vulnerable to vandalism and other shenanigans. | 2022-12-19T04:19:25.686Z |
53,955,135 | {
"externalids": {
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"ArXiv": null,
"DOI": "10.1017/S0033822200045069",
"MAG": "2214163898",
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},
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"url": null
} | In this paper, we summarize the main chemical pretreatment protocols currently used for AMS radiocarbon dating at the Oxford Radiocarbon Accelerator Unit, updating the protocols last described by Hedges et al. (1989). | 2022-12-26T05:21:38.304Z |
228,948,691 | {
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32837/yuv.v0i4.1980",
"MAG": "3097618362",
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},
"license": null,
"status": "GOLD",
"url": "http://yuv.onua.edu.ua/index.php/yuv/article/download/1980/2075"
} | У науковій статті викладається ступінь та еволюція механізму інформаційної безпеки. З'ясовано, що термін «механізм інформаційної безпеки держави» базується на основі детермінантів і принципів безпеки.
Інформаційна безпека країни може розглядатися з позиції забезпечення захисту життєво важливих інтересів усіх громадян, суспільства й держави від внутрішніх і зовнішніх загроз.
Автор зазначає, що інформаційна безпека - це динамічний елемент економіки, який адаптується до вимог свого часу. Таким чином, розглядаючи поняття інформаційної безпеки, слід виходити з визначення рівноваги економічної системи та її подальшого сталого розвитку.
Також розглядається взаємодія засобів масової інформації та державних органів влади. Аналізується впровадження інформаційно-комунікаційних технологій як фактору подальшого розвитку інформаційних процесів та ефективнішого розвитку державних політико-правових інститутів. Розглянуто можливі варіанти підвищення ефективності інформаційного забезпечення державної політики. Показано, що інформаційне забезпечення державної політики з доступом громадян до відкритих державних ресурсів є одним зі складників національних інтересів України в інформаційній сфері.
Автор доходить висновку, що з метою вдосконалення нормативно-правового забезпечення механізму інформаційної безпеки держави доцільно: на законодавчому рівні виробити єдину термінологію, характерну для цієї сфери, у формі глосарію як обов'язкового нормативного варіанта для інших правових актів, що належать до інформаційної безпеки; внести категорію інформаційної безпеки держави в Єдиний державний реєстр нормативно-правових актів; уточнити положення Доктрини інформаційної безпеки України, визначивши, що об'єктом інформаційної безпеки є забезпечення права на інформацію, права на захист від небезпечної інформації, права на недоторканність приватного життя громадян. | 2022-12-30T00:14:01.686Z |
138,890,051 | {
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"DOI": "10.2474/TROL.11.376",
"MAG": "2342775252",
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},
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"url": null
} | Semi-solid lubricants, such as grease and gels, are mixtures of oil, thickeners, and gel agents. In this study, the concentration of the urea thickener and gel agent at the point of elastohydrodynamic lubrication (EHL) contact was investigated by in situ observation with a micro-Fourier transform infrared spectrometer (micro-FTIR). Micro-FTIR was used in conjunction with a ball-on-disk lubrication tester. The lubricant film was analyzed by micro-FTIR under dynamic conditions. Characteristic peaks correlating to the C-H stretching mode at 2850-3000 cm and the N-H stretching mode at 3000-3500 cm were found to originate from the oil and the urea thickener and gel agent, respectively. The concentration of the thickener and gel agent were estimated from these characteristic IR peaks. The results showed that the concentration of urea thickener and gel agent was increased drastically at the Hertzian contact region. Meanwhile, infrared spectra under hydrostatic pressure were obtained using a diamond-anvil cell. It was confirmed that the hydrogen bonding of the urea thickener and gel agent was stabilized under high-pressure conditions. | 2022-06-07T20:33:11.873Z |
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