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{ "id": "cmpl-2ee3c78c59314d67af191e3e6b3c5423", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study where pioglitazone and losartan were used to treat atherosclerosis in a murine model of chronic kidney disease.', 'Both pioglitazone and losartan reduced atherosclerosis individually, but the combination of both drugs had a more significant effect, reducing atherosclerosis by 55.7%.', 'The context mentions that the combination treatment increased the macrophage area in plaques and led to more apoptotic cells.', 'It also specifies that the macrophages in the combination treatment group had more alternatively activated, anti-inflammatory M2 phenotypes.', 'The in vitro experiments showed that pioglitazone, alone and in combination with losartan, was more effective in reducing cytokine production and promoting an anti-inflammatory phenotype.', 'The answer accurately reflects these findings by stating that the combination of pioglitazone and losartan is more effective in reducing atherosclerosis and that this benefit is associated with mitigation in macrophage cytokine production, enhanced apoptosis, and a shift toward an anti-inflammatory phenotype.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 767, "total_tokens": 998, "completion_tokens": 231 } }

{ "id": "cmpl-69eda363473a4961ac35fd0f61103563", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that the analgesic efficacy of parecoxib sodium 20 to 100 mg was similar to that of ketorolac 30 mg.', 'The context also mentions that parecoxib sodium 50 and 100 mg had a significantly longer duration of analgesia than ketorolac 30 mg.', 'The answer correctly reflects that parecoxib sodium at doses of 50 and 100 mg is as effective as ketorolac 30 mg and has a longer duration of action.', 'The answer also notes that parecoxib sodium appears to be safe and well tolerated, which is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 576, "total_tokens": 719, "completion_tokens": 143 } }

{ "id": "cmpl-47b3cef80a16449a8bbb90a7c548b2a7", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context mentions that hepatotoxicity and skin necrosis are rare but serious adverse reactions of coumarin anticoagulants.', 'A retrospective analysis at the department revealed eight cases of phenprocoumon-induced hepatotoxicity, including three cases of (sub-) acute liver failure.', 'The context specifies that liver injury was predominantly of a hepatitic type, with mild portal to moderate active lobular hepatitis observed in non-fatal cases and massive confluent liver cell necroses in cases of (sub-) acute liver failure.', 'The context also provides data from the German Federal Institute for Drugs and Medical Devices, showing that 2% of possible phenprocoumon-related adverse reactions presented with hepatitis and 0.2% with liver failure.', 'The answer accurately reflects the information in the context by stating that phenprocoumon-induced liver disease is uncommon but can cause (sub-) acute liver failure.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 496, "total_tokens": 692, "completion_tokens": 196 } }

{ "id": "cmpl-3e6cbff877d04fe38fddfa17b3543112", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that elevated BNP levels are associated with increased odds of cerebral infarction, particularly in patients without angiographic vasospasm.', 'The multivariable model shows that the top quartile of BNP levels (≥ 276 pg/ml) are associated with an increased odds of cerebral infarction (OR 4.2, P = 0.009).', 'The stratified analysis indicates that the association between BNP and infarction is strongest in patients without angiographic vasospasm (OR 7.8, P = 0.006).', 'The answer accurately reflects these findings by stating that elevated BNP levels are strongly and independently associated with cerebral infarction, especially in patients without angiographic vasospasm.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 575, "total_tokens": 742, "completion_tokens": 167 } }

{ "id": "cmpl-ea705b4da5d34765be63c964bed4b358", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context mentions that the study aimed to validate the prognostic value of serum CRP levels and the STATE score in cirrhotic patients with HCC treated by transarterial embolization.', 'The context provides specific data showing that patients with CRP <1mg/dl had better overall survival compared to those with CRP >1mg/dl (20 months vs. 8 months, P=0.00186).', 'The context also states that patients with a STATE score <18 had a significantly shorter median overall survival compared to those with a STATE score ≥18 (6.73 months vs. 22.23 months, P=0.0002).', 'In multivariate analysis, a STATE score <18 was independently associated with increased mortality (HR: 2.06, CI95%: 1.28-3.34, P=0.0031).', 'These findings support the conclusion that both CRP levels and the STATE score can predict overall survival in these patients.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 567, "total_tokens": 789, "completion_tokens": 222 } }

{ "id": "cmpl-52ea9de954974426b9094b47319044f2", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context discusses the role of cAMP and phosphodiesterases (PDEs) in cardiac hypertrophy.', 'It mentions that inhibition of PDE3 and PDE4 induces hypertrophy, while inhibition of PDE2 is antihypertrophic.', 'The context specifically states that increasing cAMP levels via PDE2 inhibition is antihypertrophic and involves the generation of a local pool of cAMP.', 'The answer correctly summarizes that PDE2 inhibition can inhibit cardiac hypertrophy and highlights the therapeutic potential of this finding.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 527, "total_tokens": 650, "completion_tokens": 123 } }

{ "id": "cmpl-e205f564020e4d209242db65ddad734d", "object": "chat.completion", "created": 1719619525, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study investigating the regulation of t-PA gene expression and secretion in human astrocytes.', 'The study found that treatment with retinoids (RA) and/or the PKC activator PMA induced a time-dependent increase in t-PA mRNA and protein levels in astrocytes.', 'The combined treatment of RA and PMA resulted in a 10-fold increase in t-PA levels.', 'The study also observed increased storage of t-PA in intracellular granular structures and demonstrated regulated release of t-PA in response to forskolin and histamine.', 'The ANSWER accurately reflects these findings by stating that RA and PKC activation induce a strong up-regulation of t-PA expression and increased intracellular storage, and that regulated release of t-PA can be induced.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 539, "total_tokens": 715, "completion_tokens": 176 } }

{ "id": "cmpl-30635602c1bc4570a5a1502cb38d3e43", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where acetylcholine-induced contraction in pulmonary venous smooth muscle (PVSM) was investigated.', 'The experiment involved measuring the effects of PKC inhibition on acetylcholine dose-response and the expression and localization of various PKC isoforms.', 'The results showed that acetylcholine caused contraction, which was attenuated by PKC inhibition.', 'Specifically, PKC-alpha was expressed in PVSM cells and was found in the cytoplasm in unstimulated cells.', 'Acetylcholine activation induced translocation of PKC-alpha from the cytoplasm to the membrane, which was blocked by the muscarinic receptor antagonist atropine.', 'The other PKC isoforms did not show this translocation response to acetylcholine.', 'The answer correctly summarizes these findings by stating that acetylcholine activates PKC-alpha in PVSM, leading to its translocation and contraction.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 669, "total_tokens": 871, "completion_tokens": 202 } }

{ "id": "cmpl-dbae09a072374ed2b452af35f125d95b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study aimed at determining an optimal cut-off point for the 13C-glucose breath test (13C-GBT) for diagnosing metabolic syndrome (MS) in adolescents.', 'The study involved 136 adolescents and measured the adjusted cumulative percentage of oxidized dose (A% OD) at 180 min after administering the 13C-GBT.', 'The results showed significant differences in A% OD between healthy subjects and those with MS, indicating the test can differentiate between these groups.', 'An optimal cut-off point for A% OD was established, with a sensitivity of 81.5% and a specificity of 66.7%, which suggests the test has reasonable diagnostic accuracy.', 'Based on these findings, the answer stating that the 13C-glucose breath test could be a valid screening method to identify MS in adolescents is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 613, "total_tokens": 802, "completion_tokens": 189 } }

{ "id": "cmpl-ecc52c6f0185420685f893cac2e7f545", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The QUESTION asks whether proteomic analysis reveals molecular biological details in varioliform gastritis without Helicobacter pylori infection.', 'The CONTEXT describes a study that used proteomic analysis to identify differentially expressed proteins in varioliform gastritis compared to normal mucosa.', 'The CONTEXT mentions that 21 proteins were identified, with 11 upregulated and 10 downregulated in varioliform gastritis.', 'Specifically, the CONTEXT highlights the upregulation of TXNDC5 and downregulation of PEBP1 in varioliform gastritis, which were validated by Western blotting and RT-PCR.', 'The ANSWER states that there are changes in protein expression in varioliform gastritis and mentions the specific examples of PEBP1 downregulation and TXNDC5 upregulation.', 'The ANSWER is faithful to the CONTEXT because it accurately reflects the findings of the study described in the CONTEXT, which used proteomic analysis to identify molecular changes in varioliform gastritis.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 567, "total_tokens": 786, "completion_tokens": 219 } }

{ "id": "cmpl-fb56190f4ff642c092faf7249220bdd2", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes the echo enhancement artifact in 3D imaging of the uterus and its potential to be mistaken for the anatomic midcoronal plane by an inexperienced operator.', 'The context mentions that this artifact may have important clinical implications and suggests a technologic modification to help identify it.', 'The answer states that physicians should be aware of this artifact and review the anatomic plane before making a clinical diagnosis, which aligns with the context.', 'The answer also mentions a suggested technologic modification, which is consistent with the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 414, "total_tokens": 533, "completion_tokens": 119 } }

{ "id": "cmpl-ecf4fe0fe5be46b8bbc223f21fe726c0", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that serum CXCL12 levels were significantly higher in aSAH patients compared to controls.', 'The context mentions that CXCL12 levels were independently associated with WFNS scores and modified Fisher scores, which assess hemorrhagic severity.', 'The context specifies that CXCL12 levels predicted 6-month mortality and 6-month unfavorable outcome with high accuracy (area under curves of 0.815 and 0.809 respectively).', 'The context provides odds ratios for 6-month mortality and 6-month unfavorable outcome, indicating a strong association between elevated CXCL12 levels and poor outcomes.', 'The context concludes that CXCL12 levels were related independently to 6-month mortality and 6-month unfavorable outcome, suggesting its potential as a prognostic predictive biomarker.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 644, "total_tokens": 813, "completion_tokens": 169 } }

{ "id": "cmpl-819d853de05649d391c93562db074341", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides evidence that fat-free mass index (FFMI) is positively associated with caloric and macronutrient intake.', 'The context also mentions that fat mass index (FMI) is positively associated with caloric and macronutrient intake, but to a lesser degree than FFMI.', 'The context indicates that both FFMI and FMI are negatively associated with carbohydrate intake and positively associated with fat intake.', 'The context states that total energy expenditure (EE) predicts caloric and macronutrient intake.', 'The answer correctly summarizes that FFMI and FMI predict food and macronutrient intake, with FFMI having a greater influence.', 'The answer also accurately reflects the context by noting that FFM and FM may have opposing effects on energy homeostasis.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 658, "total_tokens": 830, "completion_tokens": 172 } }

{ "id": "cmpl-10f6740ad160474cafaca9d4d289e61c", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study where rabbits were fed a high-fat (HF) diet with and without DHEA supplementation.', 'The study observed that rabbits fed a HF diet showed various negative effects such as oxidative stress, inflammation, and cardiac impairment.', 'The CONTEXT specifically mentions that DHEA supplementation partially reduced oxidative stress, the inflammatory state, cardiac necrosis, and counteracted the shift of MHC isoforms and cardiac functionality.', 'The ANSWER states that DHEA supplementation had a beneficial effect, restoring oxidative balance, lowering lipid levels and inflammation, and preventing cellular and functional alterations of cardiac tissue.', 'The ANSWER also correctly notes that DHEA did not affect high plasma glucose levels or insulin resistance, which is consistent with the CONTEXT.', 'Therefore, the ANSWER accurately reflects the findings described in the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 525, "total_tokens": 703, "completion_tokens": 178 } }

{ "id": "cmpl-2e3ef0a6e68649ffb2e7ce7d6f7ef6e7", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context indicates that class I HDACs are promising targets for pancreatic cancer treatment, as evidenced by the effects of MGCD0103, a class I-selective HDACI.', 'The context also mentions that class IIa-selective HDACI (MC1568) and HDAC6-selective inhibitor (Tubastatin A) showed minimal effects when used alone, but they enhanced the effects of MGCD0103 when combined.', 'The context does not support the claim that classes I and II HDACs are equally effective as therapeutic targets. It suggests that class I HDACs are more effective and that combining class I with class II or HDAC6 inhibitors may be beneficial.', 'The answer incorrectly suggests that both classes I and II HDACs are equally potential therapeutic targets, which is not supported by the context.'], \"SCORE\": FAIL}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 649, "total_tokens": 831, "completion_tokens": 182 } }

{ "id": "cmpl-148332b46cab487b94e7d0e53bfd7d83", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigates the ameliorating potential of Withania somnifera root extract (WRE) against lead-induced augmentation of adrenergic response in rat portal vein.', 'The study included both in-vitro and in-vivo experiments, with in-vivo studies involving three groups of rats: a control group, a group exposed to lead, and a group exposed to both lead and WRE.', 'The results showed that WRE treatment significantly reduced elevated blood noradrenaline levels and restored noradrenaline levels in the brain of lead-exposed animals, making them comparable to the control group.', 'The context also mentions that the contractile effect of lead on the portal vein was significantly potentiated but antagonized by WRE, indicating that WRE reversed the lead-induced augmentation of adrenergic response.', 'The answer accurately reflects these findings by stating that WRE reversed the lead-induced augmentation of alpha 1-adrenoceptors mediated response, possibly by regulating catecholamine release from nerve endings, and suggests that WRE may be useful in therapeutic management of lead-induced hypertension.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 535, "total_tokens": 774, "completion_tokens": 239 } }

{ "id": "cmpl-ddf71abbed9d440493b17b1bad47991c", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that IL-33 mRNA expression was significantly higher in patients with asthma compared to healthy individuals.', 'It mentions a positive correlation between IL-33 mRNA expression and the level of FeNO, which is a marker of eosinophilic airway inflammation.', 'The context also notes that IL-33 expression was unrelated to loss of epithelial integrity but correlated with an increased expression of TLR2 and TLR4, which are involved in innate immune activation.', 'Additionally, the context specifies that IL-33 expression correlated with allergy to house dust mites (HDMs).', 'The answer accurately reflects these points by stating that IL-33 mRNA expression in bronchial mucosa is related to innate immune activation and allergic sensitization to HDM, rather than epithelial damage, and correlates with FeNO.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 672, "total_tokens": 851, "completion_tokens": 179 } }

{ "id": "cmpl-e94a3b70bc274c62843f63616d5cdd01", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study that investigated the effects of unilateral incisor disocclusion on the mandibular condylar cartilage in rats.', 'The study found no significant differences in cartilage thickness after 7 days of unilateral incisor disocclusion.', 'However, the study did find significant increases in the numbers of immunopositive cells for markers such as BrdU, TGF-beta1, ALP, and OCN, which indicate increased mitotic activity and accelerated chondrocytes maturation.', 'The ANSWER correctly states that unilateral incisor disocclusion affects the mandibular condylar cartilage at the cellular level by increasing mitotic activity and accelerating chondrocytes maturation.', \"The ANSWER also accurately notes that chondrocytes maturation appears more accelerated on the side opposite to incisor disocclusion, which is supported by the CONTEXT's mention of osteocalcin being highly expressed on the side opposite to incisor disocclusion.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 592, "total_tokens": 808, "completion_tokens": 216 } }

{ "id": "cmpl-832dd64144eb40b4986e9a64e17f3b65", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that uses derivatives of the human antibody F8 to target endometriotic lesions in a syngeneic mouse model.', 'The F8 antibody is shown to selectively accumulate in endometriotic lesions after intravenous administration.', 'Therapy experiments were conducted using F8-based immunocytokines, including F8-interleukin-10 (IL10) and F8-IL2.', 'The results indicate that the average lesion size in the F8-IL10 treatment group was significantly reduced compared to the saline control group and the F8-IL2 group.', 'Therefore, the answer stating that the antibody-mediated targeted delivery of interleukin-10 (IL10) inhibits endometriosis in a syngeneic mouse model is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 616, "total_tokens": 795, "completion_tokens": 179 } }

{ "id": "cmpl-d5cd84d8ee9d4e4393fe526050b6e657", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes an experimental study investigating the effects of resveratrol on human lens epithelial cells (LEC) apoptosis mediated by high glucose-induced oxidative injury.', 'The study found that high glucose concentrations and prolonged durations increased apoptosis, ROS, and MDA levels, while decreasing anti-apoptotic protein Bcl-2 and increasing pro-apoptotic protein Bax.', 'The addition of resveratrol to high glucose medium decreased apoptotic cells, increased anti-apoptotic protein Bcl-2, and decreased pro-apoptotic protein Bax, ROS, and MDA levels.', 'Resveratrol also increased MnSOD expression and inhibited iNOS and NF-κB activation.', 'The ANSWER states that resveratrol alleviates oxidative injury from high glucose-induced LEC and suggests that the mechanism involves inhibiting iNOS-mediated oxidative damage through NF-κB inhibition.', 'This is consistent with the findings in the CONTEXT, making the ANSWER faithful to the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 1295, "total_tokens": 1511, "completion_tokens": 216 } }

{ "id": "cmpl-da72e2f4903944d8afa4e9b68810b42d", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study that examined the predictors of long-term stroke recurrence.', 'The study found that dementia diagnosed three months after stroke onset is an independent risk factor for long-term stroke recurrence, with a relative risk (RR) of 2.71.', 'The ANSWER states that dementia significantly increases the risk of long-term stroke recurrence, which aligns with the findings presented in the CONTEXT.', 'The ANSWER also mentions that cardiac disease and sex are additional independent predictors of recurrence, which is consistent with the CONTEXT.', 'The CONTEXT provides specific statistical data supporting the increased risk associated with dementia, cardiac disease, and sex, which the ANSWER summarizes accurately.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 595, "total_tokens": 743, "completion_tokens": 148 } }

{ "id": "cmpl-24394348e38f46e89b60f2aae7037389", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context mentions that subjects with obesity had autonomic nervous abnormalities.', 'The study investigated autonomic nervous modulation in subjects with obesity and its association with indices of obesity, including waist circumference.', 'The context specifies that waist circumference and waist-to-hip ratio correlated significantly with heart rate variability measures in Asian subjects with obesity, whereas body mass index did not.', 'The answer correctly interprets that abdominal obesity (measured by waist circumference and waist-to-hip ratio) is related to autonomic nervous derangement, rather than general obesity (measured by body mass index).', 'The answer also correctly notes that this relationship may partially account for the higher risk of mortality and morbidity in subjects with obesity.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 426, "total_tokens": 579, "completion_tokens": 153 } }

{ "id": "cmpl-24fd577527504531bee3bf5e19ed1c68", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes experiments that investigated the role of AKT and ERK in CXCR4-dependent proliferation of pancreatic cancer cells.', 'It mentions that CXCL12, the ligand for CXCR4, increased phosphorylation of AKT in certain cell lines and phosphorylated ERK1/2 in an oscillatory pattern in all cell lines.', 'The context also states that inhibitors for AKT and ERK signaling (LY294002 and UO126, respectively) abrogated CXCL12-induced proliferation in various cell lines, indicating that both AKT and ERK signaling pathways are involved.', 'The answer accurately reflects the findings from the context, stating that CXCR4-induced proliferation is mediated by both AKT and ERK signaling in both murine and human pancreatic cancer cells.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 528, "total_tokens": 699, "completion_tokens": 171 } }

{ "id": "cmpl-1888965841f34f849a7f6739fb8b0bd3", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that evaluates the role of miR-1, miR-199a*, and MACC1 in controlling MET expression in human colon cancer samples.', 'It is mentioned that miR-1 was downregulated in 84.6% of the tumors and that this decrease significantly correlated with MET overexpression, particularly in metastatic tumors.', 'The context specifically states that concurrent MACC1 upregulation and miR-1 downregulation are required to elicit the highest increase of MET expression.', 'The answer accurately reflects these findings by stating that concomitant downregulation of miR-1 and increase of MACC1 can contribute to MET overexpression and metastatic behavior of colon cancer cells.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 533, "total_tokens": 694, "completion_tokens": 161 } }

{ "id": "cmpl-d7e683a2db964614823c8226bd1d8680", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study on the effects of PTEN loss of function in oligodendrocytes on remyelination.', 'The study found that during development, there was dramatic hypermyelination, but following white matter injury, there was no detectable improvement in remyelination.', 'The study also observed progressive myelin sheath abnormalities and massive axon degeneration in mutant animals.', 'The answer correctly summarizes that PTEN function in oligodendrocytes is required to regulate myelin thickness and preserve axon integrity.', 'The answer also accurately states that PTEN is dispensable during myelin repair, and its inactivation confers no detectable benefit.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 590, "total_tokens": 742, "completion_tokens": 152 } }

{ "id": "cmpl-41e5c182011949359ec199df199ca948", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT discusses the reproductive health and family planning needs of HIV-infected women in Sub-Saharan Africa.', 'It mentions that most HIV-infected women in this region bear children and have a high unmet need for contraception.', 'The CONTEXT also highlights the importance of access to prevention of mother-to-child transmission (PMTCT) services, skilled birth attendants, and quality post-partum care.', 'It notes that providers may lack resources and training to provide these services.', 'The CONTEXT suggests that integrating HIV and PMTCT services with family planning and reproductive health services is crucial to improve reproductive outcomes.', 'The ANSWER summarizes these points by stating that HIV-infected women in Sub-Saharan Africa have various needs related to reproductive health, including access to family planning information and options, high-quality pregnancy care, and trained providers.', 'The ANSWER also emphasizes the importance of integrated services to maximize resources and improve reproductive outcomes, which aligns with the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 506, "total_tokens": 709, "completion_tokens": 203 } }

{ "id": "cmpl-d3d25ce09c504b69b2755ed494a5ba94", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study investigating the relationship between osteoporosis and local blood supply to bones in ovariectomized mice.', 'The study found significant reductions in bone mineral density, biomechanical parameters, number of microvessels, and expression of VEGF in the tibial metaphysis of ovariectomized mice.', 'The context explicitly states that the bone microarchitecture was also disrupted in these mice.', 'The answer correctly summarizes that reduced local blood supply to the tibial metaphysis may be associated with ovariectomy-induced osteoporosis, which is supported by the findings in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 433, "total_tokens": 572, "completion_tokens": 139 } }

{ "id": "cmpl-79bebd9161bc4764941a92a73ca7da2d", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where human ARPE-19 cells were infected with human cytomegalovirus (HCMV) and treated with nicotine.', 'The results showed that HCMV infection decreased NF-kappaB levels, but nicotine treatment reduced this decrease, although it did not completely abolish it.', 'The answer correctly states that nicotine treatment dampened the downregulation of NF-kappaB in HCMV-infected ARPE-19 cells.', 'The conclusion that nicotine can serve as a cofactor to stimulate productive, lytic replication of HCMV is supported by the context, which indicates that nicotine counteracts the dampening effect of HCMV infection on NF-kappaB, making the cells more permissive for HCMV replication.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 440, "total_tokens": 607, "completion_tokens": 167 } }

{ "id": "cmpl-d1e3fbac37264b5eb2fedd4f67a1659b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study that assessed the impact of hyponatremia on admission on long-term mortality in patients with acute myocardial infarction (AMI).', 'The study found that hyponatremia was present in 18.5% of patients on admission and was significantly associated with long-term mortality, with an 83% higher risk in the age- and sex-adjusted analysis.', 'After further adjustment for various prognostic factors, hyponatremia remained a strong predictor for higher long-term mortality with a hazard ratio of 1.61.', 'The ANSWER accurately reflects the findings of the study by stating that patients with incident AMI and hyponatremia on admission showed a significantly higher risk of long-term mortality than patients without.', 'The ANSWER also correctly mentions that this strong predictive value was independent of several prognostic factors, which is supported by the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 635, "total_tokens": 836, "completion_tokens": 201 } }

{ "id": "cmpl-749ebc9f86464e40914573d6c5c1fa0b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study investigating DNA hypermethylation in plasma DNA samples from prostate cancer patients and benign prostate hyperplasia (BPH) cases.', 'The study involved 36 prostate cancer patients and 27 BPH cases, with 11 prostate cancer patients showing positive results for methylation changes in the GSTP1 gene promoter region.', 'The context mentions that 25 of the 27 BPH cases showed negative results, indicating no methylation changes in the CpG islands.', 'The answer states that hypermethylation of the CpG islands in the GSTP1 gene promoter region can be a potential plasma DNA biomarker for detecting prostate carcinoma, which aligns with the findings in the context.', 'The answer also notes the need for a larger sample size to validate the protocol, which is a reasonable conclusion based on the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 451, "total_tokens": 632, "completion_tokens": 181 } }

{ "id": "cmpl-e659cf57bfb74535b048451f81e948e7", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study that examined the expression of IL-22R1 in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).', 'The study found that IL-22R1 mRNA was expressed in 100% of controls and CRSsNP, but only in 55% of patients with recalcitrant CRSwNP.', 'The levels of IL-22R1 were significantly lower in recalcitrant CRSwNP compared to controls and CRSsNP.', 'The ANSWER states that chronic rhinosinusitis with nasal polyps is associated with decreased expression of mucosal interleukin 22 receptor, which aligns with the findings in the CONTEXT.', 'The ANSWER also mentions that failure of medical and surgical therapy in CRSwNP is associated with significantly decreased expression of IL-22R1, which is supported by the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 584, "total_tokens": 776, "completion_tokens": 192 } }

{ "id": "cmpl-ac426ab0c96a4c0c80e94eed28d83d44", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigated the effects of prostanoid receptor agonists on IgE-mediated histamine release from cultured human mast cells.', 'It specifically mentions that PGE2, an EP receptor agonist, produced concentration-related potentiation of IgE-mediated histamine release.', 'The context also states that sulprostone, an EP1/EP3 agonist, and SC-46275, a selective EP3 agonist, caused a significant increase in histamine release.', 'The answer correctly summarizes that PGE2 potentiates IgE-mediated histamine release via EP3 and/or EP1 receptors, which is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 587, "total_tokens": 732, "completion_tokens": 145 } }

{ "id": "cmpl-a7f8c6010a644b8ab9b4605bab53b5fa", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides data on the accuracy of ICU length of stay predictions made by physicians at patient admission.', 'The study found that physicians accurately predicted ICU length of stay in only 52.7% of admissions.', 'The agreement between predicted and actual ICU length of stay was poor, with a Kappa value of 0.22.', 'Predictions of ICU length of stay longer than 5 days were significantly less accurate than those of shorter durations.', 'Based on these findings, the ANSWER stating that ICU length of stay prediction is inaccurate and should not be made at admission is consistent with the data provided in the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 467, "total_tokens": 605, "completion_tokens": 138 } }

{ "id": "cmpl-5807432fae174efd8d0acba6f9059790", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT lists the factors independently associated with 30-day mortality after supratentorial ICH, which include previous antiplatelet use.', 'The ANSWER states that previous antiplatelet therapy is an independent predictor of 30-day mortality, which aligns with the information provided in the CONTEXT.', 'The CONTEXT also mentions that the study analyzed various parameters, including current antiplatelet treatment, and used logistic regression to identify independent predictors.', 'The ANSWER correctly identifies previous antiplatelet use as one of the independent predictors of 30-day mortality, which is supported by the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 512, "total_tokens": 643, "completion_tokens": 131 } }

{ "id": "cmpl-cdce863c46294bf69fb0cd230228a77b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where rats with Klebsiella pneumoniae pneumonia were treated with inhaled nitric oxide (NO) under different oxygen levels.', 'The results showed that inhaled NO reduced lung inflammation and improved bacterial clearance regardless of oxygen levels.', 'However, the context also indicates that high oxygen levels enhanced recruitment of alveolar neutrophils and pulmonary MPO activity, which are associated with increased inflammation.', 'The combination of inhaled NO with low oxygen levels (PLONO) alleviated lung inflammation similar to the PNO group, suggesting that lower oxygen levels may optimize the anti-inflammatory effects of inhaled NO.', 'The answer correctly summarizes that the beneficial effects of inhaled NO in anti-inflammation are optimized when combined with lower levels of oxygen, which aligns with the findings in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 655, "total_tokens": 832, "completion_tokens": 177 } }

{ "id": "cmpl-27dd4a5545b24b038883ac3ed5ad98d1", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that Myc-Max genomic occupancy measured by ChIP-Seq is largely, although not completely, independent of sequence specificity.', 'The answer claims that the genomic occupancy of Myc cannot be explained by its intrinsic DNA specificity, which is a stronger statement than what the context provides.', 'The context indicates that sequence specificity does play some role, although it is not the predominant factor, whereas the answer suggests it plays no role in explaining genomic occupancy.', 'Therefore, the answer is not faithful to the context because it overstates the independence of Myc-Max genomic occupancy from sequence specificity.'], \"SCORE\": FAIL}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 515, "total_tokens": 648, "completion_tokens": 133 } }

{ "id": "cmpl-ddace398a1554a70a71679207885228f", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that video electroencephalography monitoring (VEM) is the gold standard for differentiating between epileptic and non-epileptic seizures.', 'The study mentioned in the context showed that VEM revealed a diagnosis in 80% of cases, with epilepsy being diagnosed in 38% and rejected in 43% of cases.', 'The context also notes that among patients referred for antiepileptic drug treatment, 29% did not have epilepsy, indicating that VEM helps in identifying those without epilepsy.', 'The answer correctly summarizes that VEM is effective in differentiating between epileptic and non-epileptic seizures and supports its use for making correct diagnoses and avoiding unnecessary treatment.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 479, "total_tokens": 635, "completion_tokens": 156 } }

{ "id": "cmpl-651e12e1ad3b41319744b245b06f1466", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study where nonresponders to previous hepatitis C virus (HCV) therapy were treated with peginterferon and ribavirin, and then with the addition of SAMe.', 'The study results showed that the second phase slope of viral decline was improved with SAMe, indicating better early viral kinetics.', 'The context also mentions that the induction of interferon-stimulated genes (ISGs) in peripheral blood mononuclear cells (PBMCs) was significantly greater during the course where SAMe was added.', 'The answer accurately reflects these findings by stating that SAMe improves early viral kinetics and increases ISG induction in nonresponders to previous therapy.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 619, "total_tokens": 769, "completion_tokens": 150 } }

{ "id": "cmpl-87c6fe69ca8d4ae8a873538803443b65", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides detailed information from a retrospective analysis of a prospectively collected database.', 'The study found that serum albumin level is a significant predictor of peritonitis, with a rate ratio of 0.79 per 1-g/dL increase in albumin level.', 'Patients with an initial serum albumin level less than 2.9 g/dL had a significantly higher peritonitis rate compared to those with an initial serum albumin level of 2.9 g/dL or greater.', 'The multivariate analysis also identified albumin level as a predictor of peritonitis with a rate ratio of 0.74.', 'The answer accurately reflects the findings from the context, stating that hypoalbuminemia at the start of PD therapy is an independent predictor of subsequent peritonitis.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 715, "total_tokens": 890, "completion_tokens": 175 } }

{ "id": "cmpl-1d650b2c665343308a1d8667b6df7160", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides data on the responses of skin sympathetic nerve activity (SSNA) and skin blood flow during whole-body heating in both chronic heart failure (CHF) patients and healthy subjects.', 'The CONTEXT states that whole-body heat stress evoked similar SSNA activation in CHF patients (Δ891±110 U/min) and the control subjects (Δ787±84 U/min; P=0.66).', 'The CONTEXT also mentions that the elevation in forearm cutaneous vascular conductance was significantly lower in CHF patients compared to healthy control subjects.', 'The ANSWER correctly interprets that the SSNA activation during whole-body heat stress is not attenuated in CHF patients, as the data shows similar SSNA responses in both groups.', 'The ANSWER also correctly concludes that the attenuated skin vasodilator response in CHF patients is not due to a reduction in total activity of sympathetic outflow to skin, as the SSNA activation is similar in both groups.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 506, "total_tokens": 717, "completion_tokens": 211 } }

{ "id": "cmpl-0d8ab11cddc5453cae3908e579fa524e", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides detailed information on the study conducted to investigate the influence of language of publication on the methodological quality of reports of physiotherapy trials.', 'The study found that overall methodological quality was better for English reports than for reports written in other languages, with a specific beta value (β = 0.15) indicating a small influence.', 'The CONTEXT mentions that the magnitude of the influence is small, which aligns with the ANSWER stating that the influence is small.', 'The ANSWER accurately reflects the findings from the CONTEXT, indicating that language of publication is associated with methodological quality and that this influence is small.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 517, "total_tokens": 657, "completion_tokens": 140 } }

{ "id": "cmpl-73dcccec39f048b5bfabf9bfcc376373", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT indicates that secondary hyperalgesia in individuals with mild or moderate knee osteoarthritis (KOA) remains unclear.', 'The study measured pressure pain thresholds (PPT) in individuals with mild or moderate KOA and compared them to those with no osteoarthritis.', 'The study found that KOA groups (both unilateral and bilateral) reported lower PPT compared to the control group in most areas, indicating hyperalgesia.', 'The CONTEXT does not explicitly state that secondary hyperalgesia occurs regardless of unilateral or bilateral involvement, only that hyperalgesia was observed.', 'The ANSWER asserts that secondary hyperalgesia occurs regardless of unilateral or bilateral involvement, which is not directly supported by the CONTEXT.'], \"SCORE\": FAIL}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 570, "total_tokens": 732, "completion_tokens": 162 } }

{ "id": "cmpl-1084ac02f0444afba2f0a05457c39f7a", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigates the effect of growth factors (IGF-1 and bFGF) on the migration of human skeletal myoblasts.', 'It mentions that these growth factors can enhance cell migration by increasing their endogenous proteolytic activity, which helps cells migrate through the extracellular matrix.', 'The context provides evidence that IGF-1 and bFGF increased the expression of matrix metalloproteinase-9 and focused fibrinolytic system activity at the cell membrane, indicating enhanced proteolytic activity.', 'Both in vitro and in vivo experiments showed that bFGF and IGF-1 improved the migration of human myoblasts.', 'The use of specific inhibitors (BB94 or amiloride) confirmed the involvement of proteinases in the enhanced migration in vivo.', 'The answer accurately reflects the findings from the context, stating that IGF-1 or bFGF coinjection increased proteolytic activities and migratory capacity of human myoblasts.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 565, "total_tokens": 781, "completion_tokens": 216 } }

{ "id": "cmpl-d2e60602093b48ea9d4acc4c4dc82b8e", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides data on the incidence of peptic ulcer disease (PUD) and its complications over a specific period (2000-2008).', 'The CONTEXT states that the mean annual incidence of all peptic ulcers decreased significantly from 121/100,000 in 2000-2002 to 79/100,000 in 2006-2008, with an incidence rate ratio of 0.62, indicating a marked decrease.', 'The CONTEXT also mentions that the overall rate of severe complications of PUD was reduced, supporting the claim that complication rates have decreased.', 'The ANSWER correctly summarizes these points by stating that both the incidence and complication rates have markedly decreased during the study period.', 'The additional information in the ANSWER about recurrent peptic ulcer disease being associated with polypharmacy is also supported by the CONTEXT, which mentions that the use of several drugs was associated with an increased risk for recurrence.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 544, "total_tokens": 746, "completion_tokens": 202 } }

{ "id": "cmpl-3d8c19cdfd234faf973c03b061c93ce0", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that screened six candidate genes, including TBX5, for mutations in patients with early-onset atrial fibrillation (AF) of Chinese descent and controls.', 'The study identified four missense TBX5 mutations in patients with early-onset AF, which were found to increase the expression of atrial natriuretic peptide (ANP) and connexin-40 (CX40) in rat atrial myocytes.', 'The context also mentions that overexpression of one of these mutations (p.R355C) developed an atrial arrhythmia suggestive of paroxysmal AF in a zebrafish model.', 'To replicate these findings, the study screened TBX5 in early-onset AF cases from the Massachusetts General Hospital AF study and identified a novel TBX5 deletion (ΔAsp118, p.D118del).', 'No TBX5 mutations were identified in control subjects, suggesting that TBX5 mutations are associated with early-onset AF.', 'The answer states that TBX5 mutations contribute to early-onset AF and provides evidence from the study, including the identification of mutations and their functional effects, to support this claim.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 559, "total_tokens": 813, "completion_tokens": 254 } }

{ "id": "cmpl-428b52242cf84e18b21d6660e66ccfe8", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study using a murine model to test the hypothesis that recipient inflammation affects immunization to transfused red blood cells.', 'In the study, transfusion of mHEL RBCs into uninflamed mice resulted in weak immunogenicity, similar to human responses.', 'However, when recipient mice were treated with poly(I:C) to induce inflammation, there was a significant increase in both the frequency and magnitude of alloimmunization to the mHEL antigen.', 'The answer accurately reflects these findings by stating that recipient inflammation significantly enhances humoral immunization to transfused alloantigens.', 'The answer also correctly suggests that the inflammatory status of human transfusion recipients may regulate the immunogenicity of transfused RBCs, which is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 553, "total_tokens": 723, "completion_tokens": 170 } }

{ "id": "cmpl-3b426c8096a4417b96ada3551c180505", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigates the role of γ-secretase in choroidal neovascularization (CNV) and its association with oxidative stress and proinflammatory cytokines.', 'The study found that upregulation of γ-secretase and its catalytic subunit PS1 suppressed in vitro and in vivo angiogenesis, which is associated with a reduction in superoxide generation and proinflammatory factors.', 'The context specifically mentions that PS1 overexpression reduced proinflammatory factors and microglial activation in eyes with CNV compared to controls.', 'The answer correctly summarizes that γ-secretase inhibition is associated with a reduction in superoxide and proinflammatory cytokines during CNV, which aligns with the findings presented in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 575, "total_tokens": 738, "completion_tokens": 163 } }

{ "id": "cmpl-facf9dbaeb7c442e8b777e063118e37a", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where RPE cells were exposed to high glucose levels under normoxic conditions.', 'The results showed that HIF-1α levels increased with higher glucose exposure, indicating its induction and stabilization.', 'Real-time RT-PCR and ELISA results indicated elevated production of HIF-1α-induced VEGF in RPE cells.', 'Immunofluorescence and chromatin immunoprecipitation analyses suggested that ChREBP translocated to the nucleus and associated with the HIF-1α gene promoter under high glucose conditions.', 'These findings imply that ChREBP acts as a glucose sensor to up-regulate HIF-1α expression in RPE cells.', 'The answer accurately summarizes these findings by stating that high glucose activates ChREBP-mediated HIF-1α and VEGF expression in human RPE cells under normoxia.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 752, "total_tokens": 943, "completion_tokens": 191 } }

{ "id": "cmpl-58e5de4b078349428e5b2e4ec4274c2b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT states that accurate calculations of testicular volume standard deviation (SD) scores are not currently available.', 'The CONTEXT mentions that LMS-smoothed age-reference charts for testicular volume were constructed, but it does not confirm that these charts allow for the calculation of SD scores.', 'The ANSWER claims that the new reference charts do allow for the calculation of SD scores, which contradicts the CONTEXT.', 'Therefore, the ANSWER is not faithful to the CONTEXT.'], \"SCORE\": FAIL}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 465, "total_tokens": 573, "completion_tokens": 108 } }

{ "id": "cmpl-8848008c7ca64553aff20a128a12e849", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT states that the reduced expression of podocin significantly correlated with the degree of proteinuria (p = 0.032).', 'The ANSWER correctly reflects this finding by stating that the reduction of glomerular podocin expression in MCD and FSGS is related to the amount of proteinuria.', \"The CONTEXT also mentions that no correlation with age, gender, and serum creatinine level was observed, which is not addressed in the ANSWER but does not contradict the information provided about proteinuria.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 641, "total_tokens": 759, "completion_tokens": 118 } }

{ "id": "cmpl-8856a8b723e24f18bac49ccef872f14e", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an investigation into whether hyaluronan (HA)-CD44 promotes cisplatin resistance and phospholipase C (PLC)-mediated Ca2+ signaling in head and neck squamous cell carcinoma (HNSCC).', 'The study involved measuring tumor cell growth and Ca2+ mobilization in the presence or absence of HA, anti-CD44 antibody, and inhibitors of the PLC-mediated Ca2+ signaling pathway.', 'The results showed that HA reduced the ability of cisplatin to cause cell death, suggesting HA promotes CD44-dependent cisplatin resistance.', 'Fluorescence spectrophotometry demonstrated that HA promotes CD44-dependent Ca2+ mobilization in HNSCC.', 'The presence of PLC and inositol-1,4,5-triphosphate receptor inhibitors eliminated HA-mediated Ca2+ mobilization and cisplatin resistance.', 'The answer accurately reflects these findings by stating that HA-CD44 signaling influences cisplatin sensitivity and that HA-CD44 promotion of PLC-mediated Ca2+ signaling plays a role in cisplatin resistance.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 567, "total_tokens": 803, "completion_tokens": 236 } }

{ "id": "cmpl-f3a45dc76db54567b1d862fe4d01f045", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT indicates that the primary end point of the study was a composite of rebleeding and death, and the main secondary end points were the individual components of the composite (death and rebleeding).', 'The study found that the primary end point was met by 30 of 78 patients in the placebo group and 22 of 69 in the simvastatin group, with a P-value of .423, indicating no significant difference in the composite end point.', 'The CONTEXT also states that rebleeding occurred in 28% of patients in the placebo group and 25% in the simvastatin group, with a P-value of .583, indicating no significant difference in rebleeding rates.', 'However, the study did find a significant difference in mortality, with 17 patients in the placebo group dying (22%) compared to 6 patients in the simvastatin group (9%), with a hazard ratio for adding simvastatin to therapy of 0.39 and a P-value of .030.', 'The ANSWER correctly states that the addition of simvastatin to standard therapy did not reduce rebleeding but was associated with a survival benefit for patients with Child-Pugh class A or B cirrhosis.', 'The ANSWER also mentions that survival was not the primary end point of the study, which is consistent with the CONTEXT.', 'The CONTEXT notes that simvastatin did not increase survival in patients with Child-Pugh class C cirrhosis, which is not mentioned in the ANSWER but does not affect the overall faithfulness of the ANSWER to the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 825, "total_tokens": 1167, "completion_tokens": 342 } }

{ "id": "cmpl-ffe951743bbf40dba08367eb332ab51b", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides detailed information about the study of TP53 mutations in low-risk MDS patients with del(5q).', 'The study found that TP53 mutations were present in 18% of patients and were associated with an increased risk of evolution to acute myeloid leukemia.', 'The CONTEXT mentions that mutations were detected at an early phase of the disease and were associated with a lower probability of a complete cytogenetic response to lenalidomide.', 'The ANSWER accurately reflects these findings by stating that TP53 mutations may occur early in the disease and are associated with an increased risk of leukemic evolution.', 'The ANSWER also correctly notes that TP53 mutations could not be predicted by common clinical features but were associated with p53 overexpression, which is supported by the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 564, "total_tokens": 737, "completion_tokens": 173 } }

{ "id": "cmpl-c11928d1139d41859986e991b2db010c", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes how selective depletion of T regulatory (Treg) cells leads to increased susceptibility to angiotensin II-induced abdominal aortic aneurysm and promotes aortic rupture in mice.', 'The context also mentions that Treg cell depletion is associated with increased immune cell activation and a blunted interleukin (IL)-10 anti-inflammatory response, suggesting an immunoinflammatory imbalance.', 'The context further states that Il-10(-/-) mice show increased susceptibility to angiotensin II-induced abdominal aortic aneurysm and aortic rupture and are insensitive to Treg cell depletion.', 'Finally, the context notes that reconstitution of Cd28(-/-) Treg-deficient mice with Treg cells restores a balance in the immunoinflammatory response, rescues the animals from increased susceptibility to aneurysm, and prevents aortic dissection.', 'These findings in the context support the answer that natural regulatory T cells (Treg cells) limit angiotensin II-induced aneurysm formation and rupture in mice, and suggest that therapies targeting Treg responses may be effective in treating aneurysmal disease.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 561, "total_tokens": 805, "completion_tokens": 244 } }

{ "id": "cmpl-33ab4980eb3b4ce3800b0535fc29f907", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT indicates that molecular analyses initially suggested recombination within and between assemblages, which would complicate the interpretation of multi-locus genotyping data.', 'However, further population genetic analyses on an extensive dataset of G. duodenalis isolates from humans and animals showed that recombination between isolates from different assemblages is very rare or absent.', 'The ANSWER correctly reflects this conclusion by stating that recombination between G. duodenalis assemblages is either very rare or absent.', \"The ANSWER also mentions the need for further investigation into recombination between genotypes from the same assemblage and genetic exchange between the nuclei of a single cyst, which aligns with the CONTEXT's suggestion of complexity in interpreting the data.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 468, "total_tokens": 632, "completion_tokens": 164 } }

{ "id": "cmpl-3f85f6c823884573a68a1bb0fd7cfe85", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that dexmedetomidine did not have an effect on the latency or amplitude of sensory evoked potentials greater than what was prespecified as clinically relevant.', 'Although the authors could not claim equivalence on the amplitude of transcranial motor evoked responses due to variability, recordings were made throughout the study in all patients, indicating that the potentials were maintainable.', 'The answer accurately reflects the findings from the context, stating that dexmedetomidine does not change somatosensory or motor evoked potential responses by any clinically significant amount.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 550, "total_tokens": 675, "completion_tokens": 125 } }

{ "id": "cmpl-5a03070a3ade4fe297ea5a12eb9d342f", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides data on the survival rates of hinged knee replacements and mentions that the 5-year survival rate was not dependent on the primary surgical indication.', 'The CONTEXT also notes that the commonest reasons for revision were infection, peri-prosthetic fracture, and aseptic loosening.', 'The CONTEXT reports substantial improvements in Oxford Knee Score and EQ5D index, indicating good functional outcomes.', 'The ANSWER states that mid-term survival following primary hinged total knee replacement is good irrespective of the indication for surgery, which aligns with the CONTEXT.', 'The ANSWER also mentions that hinged knee replacement can be considered a viable alternative to traditional designs, which is supported by the CONTEXT\\'s findings on survival rates and functional outcomes.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 591, "total_tokens": 753, "completion_tokens": 162 } }

{ "id": "cmpl-8f11df6468f743c69bba077ba04e3349", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes that 13-MTD induces apoptosis in human bladder cancer cells.', 'It mentions that 13-MTD down-regulates Bcl-2 and up-regulates Bax, leading to mitochondrial dysfunction and the release of cytochrome c, which is a key indicator of mitochondrial-mediated apoptosis.', 'The context also states that 13-MTD activates caspases, which are proteolytic enzymes involved in the execution phase of apoptosis.', 'The regulation of AKT and MAPK pathways is mentioned as part of the mechanism by which 13-MTD induces apoptosis.', 'The answer summarizes these points by stating that 13-MTD induces mitochondrial-mediated apoptosis through the regulation of the AKT and MAPK pathways, which is consistent with the context provided.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 538, "total_tokens": 704, "completion_tokens": 166 } }

{ "id": "cmpl-b583f7b21a0a43bb916a90d71bc0dcb2", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study evaluating the clinical effect and pathological characteristics of acellular allogeneic dermal matrix in repairing unstable burn scars.', 'The study included 19 cases of unstable burn scars treated with acellular allogeneic dermal matrix and autogenous split-thickness skin graft.', 'The results showed that all wounds healed by first intention, and the grafted skin had an excellent appearance, texture, and elasticity.', 'Pathological observations indicated that the epidermis and basal membrane of the skin grafts were similar to normal skin, with regularly arranged collagen fibers and few inflammatory cells.', 'The answer accurately reflects the findings from the context, stating that acellular allogeneic dermal matrix with autogenous split-thickness skin graft can effectively repair wounds after removing unstable burn scars, and the resulting skin structure is similar to normal skin.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 630, "total_tokens": 814, "completion_tokens": 184 } }

{ "id": "cmpl-09be1463c9cf47febb9644b5ab1f3501", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT discusses a study that explores the association of the GRIN2B gene with developmental dyslexia (DD) and related cognitive traits.', 'The study found significant associations between GRIN2B markers and the categorical diagnosis of DD, performance intelligence quotient, phonemic elision, and auditory short-term memory.', 'The ANSWER states that GRIN2B contributes to DD and deficits in DD, which aligns with the findings in the CONTEXT.', 'The ANSWER also mentions that GRIN2B influences DD as a categorical trait and its related quantitative phenotypes, which is consistent with the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 525, "total_tokens": 660, "completion_tokens": 135 } }

{ "id": "cmpl-0b95d98b98994de9aeaadbb7feb318d8", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes studies that investigated the binding patterns of various antibodies, including those from celiac patients and monoclonal tissue transglutaminase antibodies, on both rodent and primate tissues.', 'The context mentions that tissue transglutaminase antibody binding patterns were identical to those seen with celiac patient sera, and that there was complete overlapping when double-staining with patients\\' sera and tissue transglutaminase antibodies.', 'The context also states that tissue transglutaminase effectively absorbed reticulin-endomysial antibodies from celiac sera, and that patients\\' sera blocked the staining of the monoclonal tissue transglutaminase antibodies.', 'These findings support the conclusion that tissue transglutaminase is the target for celiac disease-specific autoantibodies in both rodent and primate tissues.', 'Therefore, the answer is faithful to the context provided.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 531, "total_tokens": 726, "completion_tokens": 195 } }

{ "id": "cmpl-7dad2bf99fb442cc8ddac37cc4694969", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context specifies that PAPC regulates the invagination of the ear placode in Xenopus, as demonstrated by loss of function experiments.', 'It mentions that PAPC signaling via RhoA and Wnt5a/Ror2 activity is involved in this process.', 'The context also notes that depletion of Wnt5a or Ror2 phenocopies the PAPC morphant phenotype, indicating their involvement in the same pathway.', 'The answer correctly summarizes that PAPC and the Wnt5a/Ror2 pathway control the invagination of the otic placode in Xenopus.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 588, "total_tokens": 724, "completion_tokens": 136 } }

{ "id": "cmpl-16925e9f8a934e6085d437160e877152", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study evaluating the association between prenatal alcohol exposure and conduct disorder in adolescents.', 'The study found that prenatal alcohol exposure is significantly associated with an increased rate of conduct disorder in the adolescents.', 'The effect was detected above an average exposure of one or more drinks per day in the first trimester.', 'The ANSWER states that prenatal alcohol use in the first trimester is a risk factor for conduct disorder in the exposed offspring, which aligns with the findings in the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 400, "total_tokens": 511, "completion_tokens": 111 } }

{ "id": "cmpl-aea07d218ba046fab8c9248841319ee5", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes the role of dSmyd4 in Drosophila, specifically its involvement in transcriptional repression and its expression in the mesoderm, particularly in the somatic musculature.', 'The context also mentions that muscle-specific RNAi against dSmyd4 leads to severe lethality and late pupal lethality, indicating its importance in muscle development or function.', 'The answer states that dSmyd4 is a muscle-specific transcriptional modulator involved in development, which aligns with the context provided.', 'The answer also mentions the conservation of Smyd protein function between vertebrates and invertebrates, which is supported by the context that discusses the role of Smyd proteins in vertebrates and the identification of a Smyd4 homologue in Drosophila.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 556, "total_tokens": 731, "completion_tokens": 175 } }

{ "id": "cmpl-66a4129aa1b64152b6000550645f99ce", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where the effect of 8-OHDAPT, a 5-HT(1A) agonist, on the anti-cataleptic effect of L-DOPA in 6-hydroxydopamine (6-OHDA) lesioned rats was investigated.', 'The results showed that L-DOPA had an anti-cataleptic effect until day 15, which decreased by day 20.', 'Co-injection of 8-OHDAPT with L-DOPA improved the anti-cataleptic effect of L-DOPA at a specific dose (0.5 mg/kg).', 'The improvement in anti-cataleptic effect by 8-OHDAPT was abolished by NAN-190, a 5-HT(1A) receptor antagonist.', 'These findings suggest that activation of 5-HT(1A) receptors by 8-OHDAPT can improve the anti-cataleptic effect of L-DOPA in a 6-OHDA-induced rat model of Parkinson\\'s disease.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 708, "total_tokens": 935, "completion_tokens": 227 } }

{ "id": "cmpl-0c35f94c32994a428c8497e1b7985907", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context indicates that bilirubin (TB) levels are inversely associated with Ox-LDL levels in young obese individuals.', 'The multiple linear regression analysis shows that TB levels are significantly associated with Ox-LDL levels, with a standardized Beta of -0.164 and P < 0.01.', 'After removing TG and HDLc from the analysis, TB remained a significant predictor of Ox-LDL levels with a Beta of -0.202 and P = 0.002.', 'The negative Beta values for TB indicate that higher TB levels are associated with lower Ox-LDL levels, and vice versa.', 'Therefore, the answer correctly states that lower bilirubin levels may contribute to increased LDL oxidation, which is consistent with the findings in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 584, "total_tokens": 751, "completion_tokens": 167 } }

{ "id": "cmpl-1701a9e5bb5a4521aca0829070c30e86", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigated the role of Angptl2 in corneal hemangiogenesis and lymphangiogenesis using various methods such as real-time RT-PCR, immunohistochemistry, and immunofluorescent microscopic studies.', 'The study found that Angptl2 mRNA expression increased significantly in neovascularized corneas compared to normal corneas.', 'Angptl2 protein was strongly expressed in the corneal epithelium and stroma of vascularized corneas.', 'The regions showing hemangiogenesis and lymphangiogenesis were increased in K14-Angptl2 mice (which overexpress Angptl2) and reduced in Angptl2 knockout mice.', 'The number of F4/80-positive cells (macrophages) and the expressions of F4/80 and IL-1β were higher in K14-Angptl2 mice and lower in Angptl2 knockout mice.', 'Subconjunctival injection of Angptl2 siRNA significantly inhibited hemangiogenesis and lymphangiogenesis in the sutured corneas.', 'These findings suggest that Angptl2 plays a significant role in promoting corneal hemangiogenesis and lymphangiogenesis, likely through macrophage infiltration and IL-1β expression.', 'Therefore, the answer accurately reflects the findings and conclusions presented in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 633, "total_tokens": 923, "completion_tokens": 290 } }

{ "id": "cmpl-4800bd9a2c23400e82a857c351f1b8bd", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where adolescent rats were treated with olanzapine or a vehicle.', 'The experiment assessed the modulation of corticostriatal inputs onto medium spiny neurons in the adult ventral striatum.', 'The results showed that quinpirole, a D2/D3 agonist, enhanced cortically driven medium spiny neuron synaptic responses in vehicle-treated rats but reduced them in olanzapine-treated rats.', 'This suggests that olanzapine treatment during adolescence altered the D2 modulation of corticostriatal inputs in adulthood.', 'Therefore, the answer stating that olanzapine treatment leads to enduring changes in dopamine modulation of corticostriatal synaptic function is consistent with the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 524, "total_tokens": 684, "completion_tokens": 160 } }

{ "id": "cmpl-a619dd8b298041828c1df4e7a00277f1", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT mentions that habitual coffee intake has not been linked conclusively to long-term increases in basal BP, and findings are inconsistent by sex.', 'The study examined in the CONTEXT found significant interactions between coffee intake, baseline age, and length of follow-up for systolic BP (SBP) and pulse pressure in men, but not in women.', 'The ANSWER states that greater coffee intake in men is associated with steeper age-related increases in SBP and pulse pressure, which aligns with the findings in the CONTEXT.', 'The CONTEXT also notes a significant interaction of coffee intake and BMI (nonlinear) for SBP in men, which is reflected in the ANSWER mentioning overweight to obese men.', 'The ANSWER specifies that these effects are particularly notable beyond 70 years of age, which is consistent with the CONTEXT indicating a significant three-way interaction among coffee intake, baseline age, and length of follow-up.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 467, "total_tokens": 664, "completion_tokens": 197 } }

{ "id": "cmpl-bfebcc4475ae4ad0b4145f857c132ec1", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides data on the night-to-night variation in snoring severity and compares it to inter-subject variation.', 'The study found moderate reliability for the outcome measures with intraclass correlation coefficients of 0.78, 0.74, and 0.67, indicating some consistency but also significant variation.', 'The ANSWER states that one night studies are not reliable due to natural night-to-night variation, which aligns with the CONTEXT showing moderate reliability and significant variation.', 'The ANSWER also mentions that multi-night studies are recommended to reduce error, which is consistent with the CONTEXT where data was collected over four consecutive nights.', 'The CONTEXT also notes that there was no significant correlation between objective and subjective scores, which is mentioned in the ANSWER as well.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 509, "total_tokens": 676, "completion_tokens": 167 } }

{ "id": "cmpl-78ae0eaa236048dcba622d590d2ff9a5", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that GI-GVHD was identified pathologically in 11 patients, all of whom had pathological findings of GI-GVHD at the rectum.', 'It also mentions that eight patients had pathological findings of GI-GVHD at both the ileum and the rectum, and none had pathological findings of GI-GVHD at the ileum alone.', 'This information suggests that rectal biopsy is more reliable for diagnosing early GI-GVHD compared to ileal biopsy.', 'Therefore, the answer that a pathological evaluation of the rectum but not the ileum may be important and useful for the accurate diagnosis of early GI-GVHD is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 559, "total_tokens": 710, "completion_tokens": 151 } }

{ "id": "cmpl-21f6525325c74fcb9e6195908a621fbf", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes that multiple Ank proteins of O. tsutsugamushi specifically interacted with the SCF1 ubiquitin ligase complex and eukaryotic elongation factor 1 α (EF1α) in GST pull-down assays.', 'The CONTEXT also mentions that one Ank protein co-localized with these host targets and induced downregulation of EF1α potentially via enhanced ubiquitination.', 'The ANSWER states that multiple O. tsutsugamushi Ank proteins interact with the SCF1 ubiquitin ligase complex and EF1α, which is consistent with the findings described in the CONTEXT.', 'The ANSWER further suggests that this interaction could be a novel bacterial strategy for replication and/or pathogenesis, which is a reasonable inference based on the observed interactions and downregulation of EF1α.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 569, "total_tokens": 748, "completion_tokens": 179 } }

{ "id": "cmpl-52abcc52b5be423588a90940763432fd", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that activation of human T cells causes an induction of CB1 mRNA expression.', 'The context provides specific data showing an 8-fold increase in CB1 mRNA expression in primary human T cells and a 29-fold increase in Jurkat cells.', 'The context also mentions that CB2 transcription is not regulated upon T cell activation.', 'The answer correctly states that there is upregulation of CB1 in activated T cells, which aligns with the information provided in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 470, "total_tokens": 581, "completion_tokens": 111 } }

{ "id": "cmpl-c28ed5fef40841f39d40f2c89ce5cf36", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study investigating the effects of dexmedetomidine on ischaemia/reperfusion (I/R) damage in lung tissue and the oxidant/anti-oxidant system in diabetic rats.', 'The study included three groups: a diabetes control group, a diabetes plus ischaemia-reperfusion group, and a diabetes plus dexmedetomidine-ischaemia/reperfusion group.', 'The results showed that neutrophil infiltration/aggregation and lung injury scores were significantly higher in the group without dexmedetomidine compared to the group with dexmedetomidine.', 'Malondialdehyde (MDA) levels, which indicate lipid peroxidation, were significantly higher in the group without dexmedetomidine compared to the group with dexmedetomidine.', 'Catalase (CAT) activity, an anti-oxidant enzyme, was significantly higher in the group without dexmedetomidine compared to the group with dexmedetomidine.', 'These results suggest that dexmedetomidine had protective effects against lung damage caused by I/R in diabetic rats.', 'The answer accurately reflects the findings from the context, confirming that dexmedetomidine protects against post-myocardial ischaemia reperfusion lung damage in diabetic rats.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 752, "total_tokens": 1026, "completion_tokens": 274 } }

{ "id": "cmpl-c2af9101a0d7447e82fd1fc561cf0eb4", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigates whether the cell block method increases the diagnostic yield in exudative pleural effusions accompanying lung cancer.', 'The study included 40 patients and compared the diagnostic results of conventional smears and cell block methods.', 'In the benign group, the cell block method provided a diagnosis of malignancy in 4 additional patients, increasing the diagnostic yield by 10%.', 'In the malignant group, the cell block method enabled subtyping of lung cancer as adenocarcinoma in 35% of the patients.', 'The answer states that the cell block method combined with conventional smear increases the diagnostic yield, which is supported by the findings in the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 544, "total_tokens": 695, "completion_tokens": 151 } }

{ "id": "cmpl-b40838aa4ab34d3f898c9400679ffbd6", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides detailed information on the role of c-Met in melanoma biology and the effects of inhibiting c-Met using SU11274 and siRNA.', 'It mentions that c-Met is expressed in a high percentage of melanomas and that its inhibition leads to significant reductions in cell growth and induction of apoptosis.', 'The context also notes that SU11274 and siRNA induce differentiation proteins and a morphologically differentiated phenotype, indicating a potential therapeutic role.', 'The identification of c-Met mutations and the activation of c-Met in a subset of human melanomas further supports the potential of c-Met as a therapeutic target.', 'Therefore, the answer stating that c-Met is a potentially new therapeutic target for the treatment of human melanoma is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 593, "total_tokens": 763, "completion_tokens": 170 } }

{ "id": "cmpl-121e0657dff148729b6d891cd1c383f1", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study where participants took low-dose aspirin (ASA) and its effect on blood-ethanol concentrations was measured.', 'The study found that the maximum blood-ethanol concentration was distinctly lower in seven out of ten subjects after ASA treatment, and the time required to reach peak blood-ethanol levels was somewhat longer.', 'The context also mentions that the concentrations of paracetamol in plasma were lower when ethanol was ingested after ASA treatment, and the areas under the concentration-time curves were smaller.', 'The paracetamol absorption test is used to measure gastric emptying, and the results suggest that ASA treatment delayed gastric emptying.', 'Therefore, the answer accurately reflects the findings in the context, indicating that low-dose ASA decreases blood alcohol concentrations by delaying gastric emptying.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 555, "total_tokens": 731, "completion_tokens": 176 } }

{ "id": "cmpl-32dbf34898a34f64bf507eae4d3d8ec6", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study on the role of the chiA gene in the pathogenic effects of adherent invasive Escherichia coli (AIEC) in mice with colitis.', 'It specifically mentions that the chitin-binding domains encoded by the chiA gene mediate the adhesion of AIEC to intestinal epithelial cells (IECs).', 'The study found that AIEC with a deletion of the chiA gene (LF82-ΔchiA) had significantly less adhesion to IECs compared to the wild-type LF82.', 'Complementation of LF82-ΔchiA with the LF82 chiA gene increased adhesion, indicating that the chiA gene is responsible for this interaction.', 'The context also identifies specific polymorphisms in the chitin-binding domain of LF82 chiA that are required for interaction with IECs.', 'Furthermore, the context states that this interaction is mediated by an N-glycosylated asparagine in chitinase 3-like-1 on IECs.', 'Mice infected with LF82 or LF82-ΔchiA complemented with LF82 chiA developed more severe colitis, indicating that the chiA gene promotes the pathogenic effects of AIEC in mice with colitis.', 'The answer accurately reflects these findings by stating that the chitin-binding domain of chiA mediates the interaction between AIEC and IECs, leading to more severe colitis in mice.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 649, "total_tokens": 963, "completion_tokens": 314 } }

{ "id": "cmpl-222c3b46ff054e7aa3ebfddd4970cd17", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes an experiment where L-carnosine was tested for its effects on high-glucose-mediated matrix accumulation in human mesangial cells.', 'The study found that L-carnosine inhibited the deposition of collagen VI and fibronectin, which are markers of matrix accumulation.', 'TGF-β production was increased under high-glucose conditions but was normalized by the addition of L-carnosine.', 'The context also mentions that L-carnosine reduced TGF-β-mediated Smad2 phosphorylation, indicating an inhibitory effect on ALK5 signalling.', 'The answer accurately reflects these findings by stating that L-carnosine can modulate matrix accumulation by inhibiting TGF-β production and TGF-β-induced matrix accumulation via the ALK5 pathway.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 629, "total_tokens": 804, "completion_tokens": 175 } }

{ "id": "cmpl-ad9c9d7d2da042f499aeeda90a7c5672", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context mentions that cDNA microarrays were used to compare gene expression profiles between preeclamptic and normal placentas.', 'It is stated that many genes involved in cell cycle or apoptosis were more highly expressed in preeclamptic placentas than in normal placentas.', 'The answer correctly interprets that the expression of apoptosis-related genes was detected using DNA microarrays in preeclamptic placentas.', \"The answer also aligns with the context's suggestion that the change in expression of these genes might be involved in the pathogenesis of preeclampsia.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 399, "total_tokens": 534, "completion_tokens": 135 } }

{ "id": "cmpl-675e90e40f5344a3b76febdee3ebc8e6", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes the role of the heterotrimeric G protein complex in plant growth and response to salt stress.', 'It mentions that the complex is involved in controlling plant growth and cell proliferation, and that G proteins modulate plant growth under salt stress.', 'The context provides evidence from experiments with mutants (agb1-2 and rgs1-2) that show contrasting phenotypes, suggesting that G-proteins balance growth and death under salt stress.', 'The context also describes how site-directed changes in the Gα and Gβγ protein-protein interface conferred sodium tolerance, further supporting the role of G-protein signaling in salt stress response.', 'The answer accurately reflects the information in the context by stating that G-protein signaling plays a direct role in the plant growth response to salt stress and that G-proteins balance growth and death under these conditions.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 642, "total_tokens": 830, "completion_tokens": 188 } }

{ "id": "cmpl-620f5fa64b5741dc9a6078041ac636ca", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that assessed the diagnostic yield of capsule endoscopy (CE) in patients with severe obscure-overt gastrointestinal bleeding (OOGIB).', 'The study included 15 patients with severe ongoing bleeding who underwent CE after non-diagnostic standard upper and lower endoscopy.', 'CE revealed active bleeding in seven patients and signs of recent bleeding in four, with the etiology of bleeding correctly diagnosed in 11 patients (73.3%).', 'The findings from CE led to specific therapeutic measures in 11 patients (73.3%), with five managed conservatively, four endoscopically, and two surgically.', 'The context supports the conclusion that CE is useful in patients with severe OOGIB by providing positive findings in the majority of patients and having a significant impact on therapeutic procedures.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 549, "total_tokens": 726, "completion_tokens": 177 } }

{ "id": "cmpl-1798384bbd1c4e2ca4ed7c133f98f81f", "object": "chat.completion", "created": 1719619526, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context states that nitric oxide concentration and production in exhaled air were significantly higher in patients with severe cirrhosis compared to healthy controls.', 'The context provides specific data showing that nitric oxide concentration and production were higher in patients with cirrhosis (32.0 +/- 1.7 ppb and 9.2 +/- 1.3 nmol/min) compared to controls (8.9 +/- 1.0 ppb and 3.1 +/- 0.3 nmol/min).', 'The context mentions that increased nitric oxide production may contribute to pulmonary vasodilation in these patients.', 'The answer accurately reflects the information provided in the context by stating that endogenous pulmonary nitric oxide production measured from exhaled air is increased in patients with cirrhosis and liver failure, and that this increased production may contribute to cirrhosis-induced pulmonary vasodilation.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 525, "total_tokens": 719, "completion_tokens": 194 } }

{ "id": "cmpl-2d4aa1909bad4125ad94ab23ee2b0f70", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context discusses a study on how different modes of risk presentation affect risk perception among Singaporeans.', 'The study found that respondents presented with a percentage format (5%) were more likely to describe the risk as \"uncommon\" or \"rare\" compared to those presented with a frequency format (1 out of 20).', 'Although the willingness to accept the vaccine was higher for the percentage format group, this difference was not statistically significant.', 'The context does not specify that the findings are unique to highly educated people; it includes both healthcare professionals and university students in the sample.', 'Therefore, the answer extrapolates the findings to all people, including the highly educated, which is not supported by the context.'], \"SCORE\": FAIL}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 454, "total_tokens": 610, "completion_tokens": 156 } }

{ "id": "cmpl-46538e768d5443a2ab787ec49d96449c", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The study aimed to validate a molecular expression signature, including the cell cycle progression (CCP) score and molecular prognostic score (mPS), to identify stage I lung adenocarcinoma patients with a higher risk of cancer-specific death.', 'The CCP score was found to be a prognostic marker for 5-year lung cancer-specific mortality in multivariable analysis.', 'The mPS, which combines the CCP score and pathological stage, was also a significant prognostic marker for 5-year lung cancer-specific mortality.', 'The context provides evidence that both CCP score and mPS are independent prognostic markers for lung cancer-specific mortality.', \"The answer accurately reflects the findings of the study, stating that CCP score and mPS are validated as independent prognostic markers for lung cancer-specific mortality.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 599, "total_tokens": 776, "completion_tokens": 177 } }

{ "id": "cmpl-c349791481054aef9deed01f1dcd0c05", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study on multidrug-resistant Mycobacterium tuberculosis strains from the Lisbon metropolitan area, focusing on isoniazid and ethionamide resistance.', 'The study found that all strains showed high-level resistance to both isoniazid and ethionamide.', 'MIRU-VNTR typing revealed that 16 out of 17 strains belonged to the Lisboa family and had a specific mutation (C-15T) in the promoter region of the inhA gene.', 'Sequencing of the inhA gene also showed mutations in the structural region, leading to amino acid substitutions (S94A or I194T) in these strains.', 'The ANSWER states that high-level resistance to isoniazid and ethionamide in the Lisboa family is associated with inhA double mutations, which aligns with the findings in the CONTEXT.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 589, "total_tokens": 777, "completion_tokens": 188 } }

{ "id": "cmpl-23f95e9bd80d4917af715241ee77c9c8", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes the identification of calcyclin as a protein involved in the extracellular cation-sensing pathway in osteoblasts.', 'It mentions that calcyclin was found to mediate the response of MC3T3-E1 osteoblasts to extracellular cations.', 'The context also explains that calcyclin was identified using an expression-cloning strategy with a serum response element (SRE) luciferase reporter, which is directly related to the activation of SRE.', 'The answer summarizes these findings by stating that calcyclin is responsible for transferring the cation-sensing response and implicates calcyclin in the activation of SRE.', 'Therefore, the answer is faithful to the context provided.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 591, "total_tokens": 752, "completion_tokens": 161 } }

{ "id": "cmpl-5f1dddf73ae2432bad26ba4163247362", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context explains that FXR activation increases fecal cholesterol excretion and macrophage reverse cholesterol transport (RCT).', 'It also mentions that FXR activation inhibits intestinal cholesterol absorption and modulates bile acid composition.', 'The context specifies that FXR activation reduces the bile acid pool size and alters the composition by increasing the α/β-muricholic acid proportion and reducing taurocholic acid levels.', 'The answer correctly summarizes that FXR activation inhibits intestinal cholesterol absorption by modulating bile acid pool size and composition, leading to increased RCT.', \"The answer also aligns with the context's suggestion that targeting hepatic FXR and/or bile acids may be useful for boosting RCT and preventing atherosclerosis.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 495, "total_tokens": 655, "completion_tokens": 160 } }

{ "id": "cmpl-2b1fbe261b9144939faba96b677ebb64", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a study that investigates the association between serum D-dimer levels and 28-day mortality in ICU patients receiving CRRT.', 'The study enrolled 149 patients and observed the correlation between D-dimer levels and various parameters, including the APACHE II score.', 'The context mentions that the study analyzed the association between serum D-dimer levels before CRRT and 28-day mortality retrospectively.', 'Cox regression analysis was used to assess whether D-dimer could be an independent risk factor for mortality.', 'The context concludes that serum D-dimer could be a useful and easy prognostic variable for 28-day mortality in these patients.', \"Therefore, the answer 'yes' is faithful to the context as it accurately reflects the findings and conclusions presented in the study.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 411, "total_tokens": 581, "completion_tokens": 170 } }

{ "id": "cmpl-068536ef700548d59d1be0e6b8d2a2a2", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides evidence that miR-181a is associated with liver metastasis and poor prognosis in colorectal cancer (CRC).', 'It is mentioned that miR-181a promotes cell motility, invasion, tumor growth, and liver metastasis, and that silencing its expression reduces migration and invasion.', 'The context specifically identifies WIF-1 as a direct and functional target of miR-181a.', 'The context also describes the tumor-promoting effects of miR-181a, including its role in epithelial-mesenchymal transition.', 'The answer accurately reflects these findings by stating that miR-181a promotes tumor growth and liver metastasis by targeting the tumor suppressor WIF-1.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 563, "total_tokens": 724, "completion_tokens": 161 } }

{ "id": "cmpl-c6b9e880a3e448ad9c252c5baa5d95d4", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context mentions that the study investigated the influence of cytokine gene polymorphisms, including TGFβ and IL10, on frequency, risk group, and prognosis in pediatric ALL patients.', 'The context provides specific findings about TGFβ and IL10, such as TGFβ high-producer-haplotypes being correlated with a high initial blast count and elevated in high-risk ALL patients, and IL10 high-producer-haplotypes being associated with a reduced relapse rate.', 'The context also notes that IL10 was positively correlated with initial blast count, while IFNγ production was negatively correlated.', 'The answer accurately reflects these findings by stating that gene polymorphisms of TGFβ and IL10 have an impact on prognosis and risk group in ALL.', 'The answer also correctly mentions that the reduced capacity to produce pro-inflammatory cytokines at diagnosis may serve as another important risk factor, which is supported by the context.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 540, "total_tokens": 742, "completion_tokens": 202 } }

{ "id": "cmpl-b0bac963498745a6b5e76fcfc3babe3d", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT discusses a study investigating the relationship between lifetime sport and leisure activity participation and bone material and structural properties in older men.', 'The study used various methods to assess bone density, quality, and strength, and participants were categorized based on their osteogenic index (OI) scores, which measure participation in weight-bearing activities.', 'Regression analysis showed that a greater lifetime and mid-adulthood OI was associated with greater mid-femur total and cortical area, cortical bone mineral content, and the polar moment of inertia, indicating better bone size and strength.', 'The CONTEXT also mentions that no significant relationships were detected with areal or volumetric BMD at any site.', 'The ANSWER accurately reflects these findings by stating that long-term participation in sport and leisure activities, as measured by the osteogenic index, is associated with greater bone size, quality, and strength, but not BMD, in older men.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 795, "total_tokens": 991, "completion_tokens": 196 } }

{ "id": "cmpl-5db9a81e0c984f56a0753d6da29baf17", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes that VMP1 expression and autophagy are activated in pancreas beta cells as a direct response to streptozotocin (STZ), which is used to induce experimental diabetes.', 'RT-PCR analysis shows early induction of VMP1 after STZ treatment, indicating that VMP1 expression is an early event.', 'Electron microscopy and LC3 expression/LC3-VMP1 co-localization confirm the presence of autophagy morphology, which is also an early response.', 'The context explicitly states that VMP1 expression and autophagy occur early in response to STZ treatment, leading to apoptotic cell death and reduction of beta cell pool later on.', \"Therefore, the answer 'yes' is faithful to the context as it accurately reflects the early cellular events described in the context.\"], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 461, "total_tokens": 641, "completion_tokens": 180 } }

{ "id": "cmpl-438bfeda56c446109babfa8902d00757", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes how lipoxin A4 (LXA4) suppresses the development of endometriosis.', 'It mentions that LXA4 inhibits the release of inflammatory factors and the phosphorylation of p38 MAPK in IL-1β-induced endometriotic stromal cells (ESCs), which is mediated by ALX receptors.', 'The context also details the anti-proliferative and anti-invasive effects of LXA4 on ESCs.', 'The answer accurately summarizes these points by stating that LXA4 exerts anti-inflammatory, anti-proliferative, and anti-invasive effects on endometriosis through a mechanism involving the down-regulation of p38 MAPK, which is mediated by ALX receptors.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 572, "total_tokens": 737, "completion_tokens": 165 } }

{ "id": "cmpl-2f3ea398628d4a21bcda6a22bda7c598", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT describes a study examining the effects of daily changes in the Shenzhen Stock Exchange Index on cardiovascular mortality in two cities in China.', 'The study found a delayed non-linear effect of stock index changes on cardiovascular mortality, where both increases and decreases in the stock index were associated with higher cardiovascular deaths.', 'Specific statistical data is provided for the cumulative relative risk of cardiovascular mortality in both cities, showing significant increases in mortality associated with large changes in the stock index.', 'The ANSWER accurately reflects the findings of the study by stating that large ups and downs in the daily stock index might be important predictors of cardiovascular mortality.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 460, "total_tokens": 596, "completion_tokens": 136 } }

{ "id": "cmpl-b6cb81ee56cb4381b095c83b9a1e8506", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context describes a genetic study on experimental colitis in mice, identifying two susceptibility loci: one on chromosome 9 (Tnbs1) and another on chromosome 11 (Tnbs2).', 'The context specifically mentions that Tnbs2 on chromosome 11 harbors the IL-12 p40 gene and that IL-12 is a central mediator for both experimental colitis and human Crohn\\'s disease.', 'The context also details that susceptible mice have a higher serum IL-12 response to lipopolysaccharide (LPS) and that the genetic region regulating this IL-12 response colocalizes with Tnbs2 on chromosome 11.', 'The answer states that experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responses, which aligns with the information provided in the context.', 'Therefore, the answer is faithful to the context given the question.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 534, "total_tokens": 742, "completion_tokens": 208 } }

{ "id": "cmpl-458f05ee294b42148a643e74ed270b6e", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides detailed information about a study investigating the prognostic value of galectin-3 (Gal-3) in chronic heart failure (CHF) patients treated with mineralocorticoid receptor antagonists (MRAs).', 'The study included 427 CHF patients, with 101 patients treated with MRAs (MRA-Plus) and 101 patients not treated with MRAs (MRA-Neg).', 'The primary endpoint was all-cause mortality over a 3-year follow-up period.', 'Gal-3 levels were measured at baseline, and the results showed similar median values in both groups (14.0 ng/mL in MRA-Neg and 14.4 ng/mL in MRA-Plus), with a P-value of 0.132 indicating no significant difference.', 'The hazard ratios (HR) for patients with Gal-3 ≤17.8 ng/mL and Gal-3 ≥17.8 ng/mL were calculated for both groups. The HR for patients with Gal-3 ≤17.8 ng/mL was 1 (reference group) in both groups, and the HR for patients with Gal-3 ≥17.8 ng/mL was 7.4 in MRA-Plus and 9.0 in MRA-Neg. The P-values for these HR comparisons were 0.509 and 0.539, respectively, indicating no significant difference.', 'Multivariate Cox proportional hazard analysis confirmed that MRA treatment and the interaction term between MRA treatment and Gal-3 >17.8 ng/mL were not factors associated with survival.', 'The answer states that MRA treatment did not impair the prognostic value of Gal-3 assessed with a 17.8 ng/mL cut off, which aligns with the findings in the context that the HR and survival times were similar between the MRA-Plus and MRA-Neg groups.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 704, "total_tokens": 1101, "completion_tokens": 397 } }

{ "id": "cmpl-b7f62ec7b59342bcaad6f02975f87322", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The context provides data from a large study examining the association between prior antithrombotic use and clinical outcomes in acute ischemic stroke patients.', 'The study found that patients who received antithrombotics before the stroke had better outcomes compared to those who did not, after adjusting for various factors.', 'Specifically, the adjusted odds ratios indicated lower in-hospital mortality and better functional outcomes (such as higher likelihood of being discharged home, having independent ambulatory status, and having a lower modified Rankin Scale score) for those who received antithrombotics prior to the stroke.', 'The answer accurately reflects these findings by stating that previous antithrombotic therapy was independently associated with improved clinical outcomes after acute ischemic stroke.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 515, "total_tokens": 677, "completion_tokens": 162 } }

{ "id": "cmpl-b635ee85656a4f3a9c2dbeba2878dbe0", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT indicates that patients with HFSR had improved progression-free/disease-free survival (PFS/DFS) and overall survival (OS) compared to those without HFSR.', 'The ANSWER states that HFSR is an independent clinical predictor of improved survival, which aligns with the CONTEXT.', 'The CONTEXT mentions that baseline characteristics, except for UICC stage, older age, and ECOG performance status, had no impact on survival, which is reflected in the ANSWER.', 'The CONTEXT also notes that patients with HFSR had a higher rate of all-grade gastrointestinal toxicity and fatigue, but no correlation with haematological toxicity, which is accurately represented in the ANSWER.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 773, "total_tokens": 927, "completion_tokens": 154 } }

{ "id": "cmpl-4ba17c72f92c47c4a8af1655a961344c", "object": "chat.completion", "created": 1719619527, "model": "llama-3-70b", "choices": [ { "index": 0, "message": { "role": "assistant", "content": "{\"REASONING\": ['The CONTEXT provides a detailed summary of the epidemiology and prevention of HFRS in China, including its history, prevalence, and research achievements.', 'The CONTEXT mentions that HFRS was first recognized in 1931 and has been prevalent in many parts of China since 1955, with a significant number of cases and deaths.', 'The CONTEXT highlights the development of vaccines and the identification of different types of HFRS, as well as the ongoing challenges and uncertainties in understanding the disease.', 'The ANSWER acknowledges the progress made by Chinese workers in the epidemiology and prevention of HFRS, which aligns with the CONTEXT.', 'The ANSWER also notes the need for reinforced control measures and the ongoing research priorities, which is consistent with the CONTEXT\\'s discussion of ongoing challenges and the need for further understanding.'], \"SCORE\": PASS}" }, "logprobs": null, "finish_reason": "stop", "stop_reason": null } ], "usage": { "prompt_tokens": 879, "total_tokens": 1057, "completion_tokens": 178 } }