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vllm-4739102fb0ee41fe9f39e6234c0a4f2b | 17624643 | {
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"content": "{\"REASONING\": ['The context states that vitamin D deficiency has been associated with the metabolic syndrome in general.', 'The study mentioned in the context specifically investigated this association in morbidly obese patients.', 'The results showed that vitamin D deficiency was more prevalent in morbidly obese patients with the metabolic syndrome compared to those without (60.9% vs. 33.3%, P = 0.023).', 'There was an association between the prevalence of the metabolic syndrome and serum concentrations of 25-hydroxyvitamin D (P = 0.038).', 'Additionally, the context mentions that serum high-density lipoprotein cholesterol concentrations were lower and triglycerides levels were higher in the vitamin D-deficient group, which are indicators of the metabolic syndrome.', 'Therefore, the answer stating that vitamin D deficiency is associated with the metabolic syndrome in morbidly obese patients is supported by the context.'], \"SCORE\": PASS}"
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vllm-8a71804788d94d45931e4691f5837007 | 20810157 | {
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"content": "{\"REASONING\": ['The context provides detailed information about the analysis of nasal polyps from both Belgian and Chinese patients.', 'It mentions that nasal polyps are often associated with asthma and that the study aimed to identify mucosal factors associated with asthma comorbidity.', 'The context specifies that IL-5 and IgE antibodies to Staphylococcus aureus enterotoxins were identified as key factors in the inflammatory patterns of nasal polyps.', 'It states that the presence of IL-5 and enterotoxin IgE in tissue samples was associated with increased total IgE and eosinophil cationic protein concentrations, which significantly predicted asthma.', 'The context also confirms that these findings were consistent across both Belgian and Chinese patient groups, indicating that the association is not limited to a specific ethnicity.', 'Therefore, the answer accurately reflects the information provided in the context, stating that the presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma.'], \"SCORE\": PASS}"
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vllm-ab09195f02be4bac84db186a7011c963 | 18616665 | {
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"content": "{\"REASONING\": ['The context describes experiments that investigated voluntary ethanol (EtOH) intake in adolescent and adult rats using a modified sucrose-fading paradigm.', 'The context specifies that adolescent rats consumed more EtOH than adults at higher concentrations (10% and 20%) but not at lower concentrations (2% and 5%).', 'The context also mentions that adolescent rats voluntarily consumed more EtOH than adults when maintained at 5% sucrose-10% EtOH (5S/10E) and initially presented with 5S/10E and 5S/20E EtOH concentrations.', 'The answer states that adolescent rats consume more EtOH relative to adults, which is consistent with the findings in the context.', 'The answer also notes that these results were observed using sweetened EtOH solutions in a limited access paradigm, which aligns with the context.'], \"SCORE\": PASS}"
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vllm-fc6a94a5df1b49c9938020116952741b | 22349088 | {
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"content": "{\"REASONING\": ['The CONTEXT provides data on the performance of different models in predicting CHD risk.', 'The AUC values for the models are: ACRS (0.748), ACRS+9p21 (0.751), ACRS+CIMT-P (0.763), and ACRS+CIMT-P+9p21 (0.766).', 'The addition of 9p21 to ACRS only slightly improves the AUC (0.748 to 0.751).', 'The addition of CIMT-P to ACRS improves the AUC more significantly (0.748 to 0.763).', 'The combination of CIMT-P and 9p21 with ACRS further improves the AUC but only minimally (0.763 to 0.766).', 'The ANSWER states that adding 9p21 allele information to CIMT-P minimally improves CHD risk prediction, which aligns with the small increase in AUC from 0.763 to 0.766.'], \"SCORE\": PASS}"
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vllm-7b501f6ebf6f4b8f818f27cdd8a66769 | 11509232 | {
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"content": "{\"REASONING\": ['The context explains that JNK signaling is initially active in both the amnioserosa and the leading edge of the epidermis.', 'It is downregulated in the amnioserosa but not in the leading edge prior to dorsal closure.', 'The downregulation of JNK signaling in the amnioserosa is essential for proper dorsal closure, as persistent JNK activity in the amnioserosa leads to defective focal complexes and failure of dorsal closure.', 'The answer correctly states that downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo.'], \"SCORE\": PASS}"
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vllm-c37563d4596d404fac7899f429ba85fe | 19674198 | {
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"content": "{\"REASONING\": ['The QUESTION asks specifically about the frequency of matrix metalloproteinase-26 (MMP-26) in squamous cell carcinomas (SCCs) of immunosuppressed compared to immunocompetent patients.', 'The CONTEXT provides detailed information about the study comparing MMP and TIMP expression profiles in SCCs of immunosuppressed (IS) and immunocompetent (IC) patients.', 'The CONTEXT states that among all MMPs studied, only MMP-26 showed significantly more intense staining in cancer cells of the post-transplant group (IS) compared to the IC group, with a p-value of 0.01.', 'The ANSWER concludes that MMP-26 may contribute to the more aggressive behavior of SCCs in OTRs, which aligns with the CONTEXT indicating higher MMP-26 expression in IS patients.', 'The ANSWER also mentions MMP-9, which is not directly relevant to the QUESTION about MMP-26 frequency. However, the CONTEXT does mention MMP-9 expression in stromal macrophages and neutrophils, but this does not affect the conclusion about MMP-26.'], \"SCORE\": PASS}"
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vllm-4426c24bc84b4678b57a9c67c4292522 | 17615154 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context describes the investigation of nucleoside analogues against various bacteria and the characterization of deoxyribonucleoside kinases (dNKs) from different bacterial species.', 'It mentions the susceptibility of different bacteria to specific nucleoside analogues and the role of dNKs in activating these analogues.', 'The context provides specific examples of dNKs from Salmonella enterica and Bacillus cereus, showing their ability to phosphorylate and activate certain nucleoside analogues.', 'The context supports the idea that dNKs activate nucleoside analogues in a species-specific manner, as it highlights the specific interactions between dNKs from different species and particular nucleoside analogues.', \"The answer accurately reflects the information in the context, stating that bacterial dNKs efficiently activate nucleoside analogues in a species-specific manner and suggesting their potential as antibiotics.\"], \"SCORE\": PASS}"
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vllm-b6c60973b4d044f49b51517ba76fada1 | 20712895 | {
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"content": "{\"REASONING\": ['The context describes the identification and characterization of zebrafish Kv3.3 channels and their functional properties.', 'It mentions that mutations in human Kv3.3 cause spinocerebellar ataxia type 13 (SCA13) and that analogous mutations were introduced into zebrafish Kv3.3 channels to assess their functional effects.', 'The context provides specific details about the effects of two mutations (R335H and F363L) on zebrafish Kv3.3 channel function, which are similar to the effects of corresponding mutations in human Kv3.3 channels.', 'The context concludes that zebrafish Kv3.3 channels exhibit strong functional and structural homology with mammalian Kv3.3 channels, suggesting that zebrafish can be a useful model system for studying SCA13.', 'The answer accurately reflects the information in the context by stating that the functional effects of SCA13 mutations are well conserved between human and zebrafish Kv3.3 channels and that zebrafish will be a useful model system for studying SCA13.'], \"SCORE\": PASS}"
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vllm-f931a6e17c23483aa49c620d12ca2afb | 20846423 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that investigated the feasibility of using liver transcriptomics to assess the effects of DHEA treatment in bovines.', 'The study involved comparing gene expression profiles between DHEA-treated and control animals, and it was found that there were significant differences in gene expression profiles between the groups.', 'The study also used Gene Set Enrichment Analysis (GSEA) to validate the results and found that certain gene sets were significantly enriched in DHEA-treated animals.', 'The ANSWER states that the study showed that genomic biomarkers can be used to screen for (pro)hormone abuse, but it also highlights the need for better insight into genomic variability in the control population.', 'The ANSWER is faithful to the CONTEXT because it accurately reflects the findings and conclusions presented in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-1593747876b9404492e609cda4cd552d | 27142280 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context explains that postural control requires multiple inputs and that age-related reduction in foot-sole somatosensation reduces postural sway complexity.', 'It mentions that sub-sensory vibrations applied to the foot soles reduce the speed and magnitude of sway and improve mobility in older adults.', 'The hypothesis is that these vibration-induced improvements are associated with an increase in postural sway complexity.', 'The study results show that foot sole vibrations at 70 and 85% of sensory threshold increased mediolateral sway complexity during both eyes-open and eyes-closed standing.', 'These vibration-induced increases in complexity correlated with improvements in the timed up-and-go (TUG) test of mobility.', 'Therefore, the answer stating that sub-sensory foot sole vibrations augment the physiologic complexity of postural control is supported by the context.'], \"SCORE\": PASS}"
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vllm-784c612e3e1447209ae28c8c9deb2d56 | 12028447 | {
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"content": "{\"REASONING\": ['The context describes a process where proximal tubular cells play a role in promoting fibrogenesis.', 'It mentions that abnormal protein uptake by proximal tubular cells leads to the accumulation of myofibroblasts and the expression of TGF-beta1, which is a key mediator of fibrogenesis.', 'The context also notes that TGF-beta1 mRNA appears in proximal tubular cells and infiltrating cells over time, indicating a role for TGF-beta1 in the fibrogenic process.', 'The answer summarizes this by stating that profibrogenic signaling from proximal tubular cells is implicated in progressive tubulointerstitial injury, which aligns with the details provided in the context.'], \"SCORE\": PASS}"
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vllm-a9781df52b284d479d8c153af449ec70 | 16530322 | {
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"content": "{\"REASONING\": ['The context states that current staging for renal cancer does not directly rely on tumor size.', 'The study examined the increment in accuracy related to the inclusion of pathologically determined tumor size in predicting nodal metastases, distant metastases, and cancer-specific survival.', 'Tumor size was a statistically significant predictor of all outcomes in both univariate and multivariate models.', 'The addition of tumor size to the models increased predictive accuracy by 3.7% to 0.8% for either 1997 or 2002 TNM categories.', 'The answer correctly summarizes that tumor size is a significant predictor and may warrant inclusion in future TNM revisions, improving the accuracy of predictions.'], \"SCORE\": PASS}"
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vllm-616905afc68d4084ab801764c0990f29 | 24763164 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study that included eight studies on the effectiveness of fluoride toothpaste in children under seven.', 'The study found significant caries reduction at the surface, tooth, and individual levels when standard fluoride toothpastes were compared to placebo or no intervention.', 'The results showed a prevented fraction (PF) of 31% at the surface level, 16% at the tooth level, and a relative risk (RR) of 0.86 at the individual level, indicating a significant reduction in caries.', 'The ANSWER states that standard fluoride toothpastes are effective in reducing dental caries in the primary teeth of preschool children and recommends their use for this age group.', 'The ANSWER is consistent with the findings presented in the CONTEXT, making it faithful to the CONTEXT.'], \"SCORE\": PASS}"
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vllm-51762eba4bef425cb22ed1f2d66dee25 | 11164124 | {
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"content": "{\"REASONING\": ['The context describes a study that analyzed the impact of lifestyle interventions on self-reported dietary intakes of sodium and potassium.', 'The study found that mean self-reported sodium intakes were biased lower among participants assigned to the combined weight loss and sodium reduction intervention, but were unaffected by the other interventions.', 'The context also mentions that the repeatability of self-report measures increased slightly over time, particularly among participants assigned to sodium interventions.', 'Additionally, errors in self-reported sodium and potassium intakes were correlated before the intervention but became uncorrelated among individuals assigned to sodium restriction interventions.', 'The answer states that lifestyle interventions may influence not only diet intake but also the measurement of diet intake, which aligns with the findings in the context.'], \"SCORE\": PASS}"
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vllm-2b71e9225f154c88a16e61814a944b8b | 22590653 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context describes how the CNGRC motif is an APN ligand that targets tumor vasculature.', 'It explains that modifying human plasminogen kringle 5 (hPK5) by adding a CNGRC motif (NGR-hPK5) improved its antiangiogenic activity and tumor-targeting ability compared to wild-type hPK5.', 'NGR-hPK5 showed stronger inhibitory effects on endothelial cells and a higher localization to tumor tissues than wild-type hPK5.', 'The modified NGR-hPK5 effectively inhibited the growth of mouse Lewis lung carcinoma and human colorectal adenocarcinoma cells in tumor-bearing mice.', 'Therefore, the answer stating that the addition of the NGR sequence improved the ability of hPK5 to inhibit angiogenesis and tumor growth is supported by the context.'], \"SCORE\": PASS}"
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vllm-5e4a7993657940eabf087659d78656cf | 11546720 | {
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"content": "{\"REASONING\": ['The context describes an experiment where isolated rat hearts were subjected to ischemic preconditioning with and without thiopentone.', 'The results showed that ischemic preconditioning improved myocardial function and reduced cellular injury compared to the control group.', 'The administration of thiopentone did not alter the improvement in myocardial function or the reduction in cellular injury caused by ischemic preconditioning.', 'Therefore, the context indicates that thiopentone does not block the cardioprotective effects of ischemic preconditioning in isolated rat hearts.', \"The answer 'no' correctly reflects the findings in the context, making it faithful to the context provided.\"], \"SCORE\": PASS}"
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vllm-065ee5c909dc4ea59dcbc7d76b46ecf2 | 26477894 | {
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"content": "{\"REASONING\": ['The context describes the development of a computer simulation called iHome, which uses data from 60 Australian aged care homes, 900+ clients, and 700+ aged care staff.', 'The context mentions that Bayesian analysis of simulated trial data will determine the influence of different iHome characteristics on care service quality and client outcomes.', 'The context provides interim results indicating that a person-centered aged care home and care/lifestyle services can produce positive outcomes for aged care clients in the simulated environment.', 'The answer states that computer modeling with randomized-controlled trial data informs the development of person-centered aged care homes and that further testing will define essential characteristics of such a care home.', 'The answer is consistent with the context, which describes the use of computer simulation and analysis of trial data to inform the development of person-centered aged care homes.'], \"SCORE\": PASS}"
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vllm-3820b21480b54400b65dd84f5fb27d92 | 25589556 | {
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"content": "{\"REASONING\": ['The context discusses the role of HDL particle size in ABCA1-mediated macrophage cellular cholesterol export.', 'It mentions that ABCA1 is the major mediator of macrophage cholesterol efflux to HDL, particularly to small, dense HDL subfractions (HDL3b and HDL3c).', 'The answer states that small, dense HDL subfractions are the most efficient mediators of cholesterol efflux and that ABCA1 mediates cholesterol efflux to these subfractions.', 'The answer also suggests that HDL-directed therapies should target increasing the concentrations or the cholesterol efflux capacity of small, dense HDL species in vivo, which aligns with the context.', 'Therefore, the answer is faithful to the context as it accurately reflects the information provided about the critical role of HDL particle size, specifically small, dense subfractions, in ABCA1-mediated cholesterol export.'], \"SCORE\": PASS}"
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vllm-5facca27fe0f4f10bde3cb09ebe1be56 | 10632523 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that examines the production of CC-chemokines by human mononuclear cells and bone-derived cells in response to stimulation by periodontal pathogens P. gingivalis and A. actinomycetemcomitans.', 'The study found that these pathogens induce the production of specific CC-chemokines such as MIP-1alpha, MCP-1, and RANTES in different cell types.', 'The ANSWER states that periodontal pathogens stimulate CC-chemokine production and explains that different cell types respond differently to the same stimulus, leading to tissue-specific recruitment of leukocytes.', 'This explanation is consistent with the findings in the CONTEXT, making the ANSWER faithful to the CONTEXT.'], \"SCORE\": PASS}"
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vllm-d14e2e1b37f34f18a2399ef9a57dcfae | 27539026 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The CONTEXT discusses a study that investigates the effects of reading on a self-luminous tablet versus a physical book on sleep after daytime bright light exposure.', 'The study found no differences in sleep parameters and pre-sleep saliva melatonin levels between the tablet reading and physical book reading conditions.', 'The ANSWER states that bright light exposure during daytime has previously been shown to abolish the inhibitory effects of evening light stimulus on melatonin secretion.', 'The ANSWER suggests that exposure to bright light during the day may help combat sleep disturbances associated with the evening use of electronic devices emitting blue light.', 'However, the CONTEXT does not provide evidence or mention that daytime bright light exposure abolishes the inhibitory effects of evening light stimulus on melatonin secretion.', 'The CONTEXT only mentions that there were no differences in sleep parameters between the tablet and physical book reading conditions, but it does not link this to the effects of daytime bright light exposure.', 'Therefore, the ANSWER introduces information not supported by the CONTEXT and is not faithful to the CONTEXT.'], \"SCORE\": FAIL}"
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vllm-0465743a75444af48e23e1f99ea3982c | 12567340 | {
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"model": "llama-3-70b",
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"content": "{\"REASONING\": ['The context describes a study comparing the analgesic quality of femoral block versus intra-articular injection of local anesthetic after ACL reconstruction.', 'The study included 80 patients divided into two groups: one receiving a femoral block and the other receiving an intra-articular injection.', 'The context provides specific metrics showing that the femoral group had better outcomes: higher analgesic duration, lower morphine use, and lower VAS scores compared to the intra-articular group.', 'The answer accurately reflects these findings by stating that femoral nerve block provides better analgesia and a significant morphine-sparing effect compared to intra-articular injection.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study that investigates the changes in the radial artery (RA) when used as a coronary artery bypass conduit.', 'The study found that the RA grafts in the coronary circulation had a significantly larger mean diameter compared to the native RA and ITA grafts.', 'The context also notes that the RA coronary grafts showed a reduction in the thickness of the medial layer and a less well-defined muscular component, with interposition of elastic tissue.', 'This morphological change is consistent with a transformation from a muscular to an elastomuscular artery.', 'The context further mentions that the RA coronary grafts exhibited moderate constriction in response to serotonin, which is different from the strong spastic reaction observed in the native RA.', 'These findings support the conclusion that implantation in the coronary circulation leads to morphofunctional changes in the RA, transforming it from a muscular to an elastomuscular artery.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study where chronic hepatitis C patients who achieved an immediate virological response (IVR) were treated with a 12-week course of PEG-IFN alpha2a monotherapy.', 'The study results showed that 35 out of 38 patients (92.1%) achieved a sustained virological response (SVR), indicating that the treatment was highly effective for these patients.', 'The context specifies that the treatment was effective for patients with low pretreatment HCV RNA load and who exhibited IVR, which aligns with the question about predicting the success of short-term peg-interferon monotherapy based on immediate virological response.', \"The answer states that short-term PEG-IFN alpha2a monotherapy is highly effective for chronic hepatitis C patients who have low pretreatment HCV RNA load and exhibit IVR, which directly reflects the findings presented in the context.\"], \"SCORE\": PASS}"
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vllm-c582d6728de149e9bfc74767c5a3e25c | 24798308 | {
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"content": "{\"REASONING\": ['The context describes a study evaluating the immune response to sequential GalT-KO and allogeneic skin grafts.', 'It mentions that rejection of primary GalT-KO skin grafts did not lead to sensitization to alloantigens nor acceleration of rejection of allogeneic skin grafts.', 'Similarly, presensitization with allogeneic skin did not lead to accelerated rejection of xenogeneic skin.', 'These findings suggest that there is no cross-sensitization between GalT-KO and allogeneic skin grafts, allowing for serial grafting.', 'The answer correctly interprets these findings, stating that GalT-KO skin grafts could be used as an early treatment without precluding subsequent use of allografts, and that serial grafting could provide extended temporary burn wound coverage.'], \"SCORE\": PASS}"
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vllm-36efa472e0184469b5c8c9501f89127a | 19738375 | {
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"content": "{\"REASONING\": ['The CONTEXT provides data on the relationship between the number of stroke physicians (SPs) and the management of IV rt-PA in hospitals.', 'The study found that having three or more SPs was associated with a lower likelihood of discontinuing IV rt-PA (odds ratio = 0.37) and a higher likelihood of starting IV rt-PA (odds ratio = 6.19).', 'The ANSWER states that the number of SPs available may contribute to the management of rt-PA hospitals, which aligns with the findings in the CONTEXT.', 'Therefore, the ANSWER is faithful to the CONTEXT given the QUESTION.'], \"SCORE\": PASS}"
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vllm-dec83183a0054c5d8142cfceed8c865f | 18067970 | {
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"content": "{\"REASONING\": ['The CONTEXT specifies that the study examined the phenotypes of AMD patients with the CFH Y402H variant.', 'The study compared AMD phenotypes between carriers and noncarriers of the CFH Y402H variant.', 'Out of 34 phenotypic features analyzed, only peripheral reticular pigmentary change (PRPC) was significantly associated with the CFH Y402H variant.', 'The ANSWER correctly states that the CFH Y402H polymorphism is associated with PRPC.', 'The ANSWER also appropriately suggests that AMD grading methods should consider incorporating peripheral retinal changes, which aligns with the CONTEXT.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context indicates that neoadjuvant docetaxel is effective in treating large locally advanced breast cancers, with an objective response rate of 75%.', 'The context also states that overall survival at 24 months was significantly better in patients who achieved a clinical response (85% vs. 51%, p = 0.008).', 'The context mentions that apoptosis was induced in clinical responders (p = 0.002), indicating that docetaxel induces apoptosis as a mechanism of action.', 'Therefore, the answer accurately reflects the information provided in the context, stating that neoadjuvant single agent docetaxel is effective and that clinical response is associated with improved survival, and that docetaxel acts by inducing apoptosis.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The CONTEXT discusses the distinction between fibrillary glomerulonephritis (FGN) and immunotactoid (microtubular) glomerulopathy (IT/MTGN) based on ultrastructural organization and associated immunologic features.', 'The CONTEXT provides details on the clinical and immunological differences between FGN and IT/MTGN, including the presence of monotypic deposits, monoclonal gammopathy, and lymphoproliferative disease in IT/MTGN, which are absent in FGN.', 'The ANSWER acknowledges the importance of identifying ultrastructural patterns in these nephropathies and mentions GN with organized microtubular monoclonal deposits (GOMMID), which is related to immunotactoid (microtubular) GN.', 'The ANSWER is faithful to the CONTEXT because it aligns with the discussion on the distinct immunologic features and the significance of ultrastructural patterns in distinguishing between FGN and IT/MTGN.'], \"SCORE\": PASS}"
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vllm-da425f8a6e2a4db998ecea03c9676f9b | 24449823 | {
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"content": "{\"REASONING\": ['The QUESTION asks whether TGF-β-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12.', 'The CONTEXT provides detailed information on how TGF-β induces malat1 expression, which in turn promotes epithelial-mesenchymal transition (EMT) and metastasis in bladder cancer cells.', 'The CONTEXT specifically mentions that malat1 is associated with suz12, leading to decreased E-cadherin expression and increased N-cadherin and fibronectin expression, which are indicative of EMT and metastasis.', 'The CONTEXT also states that targeted inhibition of malat1 or suz12 suppresses the migratory and invasive properties induced by TGF-β and inhibits tumor metastasis in animal models.', 'The ANSWER summarizes these findings by stating that malat1 is an important mediator of TGF-β-induced EMT and suggests that malat1 inhibition may be a promising therapeutic option for suppressing bladder cancer progression.', 'Therefore, the ANSWER is faithful to the CONTEXT as it accurately reflects the key findings and implications discussed in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-b93009c72561403ebfdcf9ca49a0071d | 25481622 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study comparing brain responses to rewards in women remitted from anorexia nervosa (RAN) and healthy comparison women (CW) during hunger and satiety.', 'The study found that in CW, hunger increased activation in reward salience circuitry, while satiety increased activation in cognitive control circuitry.', 'In contrast, the RAN group did not show differences in brain response to rewards during hunger and satiety.', 'The ANSWER states that women remitted from AN did not increase activation of reward valuation circuitry when hungry and showed elevated response in cognitive control circuitry, which aligns with the findings in the CONTEXT.', 'The ANSWER also explains that decreased sensitivity to hunger\\'s motivational drive may contribute to food restriction in AN, which is consistent with the CONTEXT.'], \"SCORE\": PASS}"
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vllm-f8908bbbd6d24447ab5c9778a5e77276 | 15922431 | {
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"content": "{\"REASONING\": ['The CONTEXT provides data from a study on the willingness of men to participate in prostate cancer screening with or without digital rectal examination (DRE).', 'The study found that only 78% of men would participate in screening that included both DRE and PSA, compared to 100% participation in PSA-alone screening.', 'The results showed that PSA-alone screening would detect 27 more cancers and perform 560 fewer negative biopsies compared to PSA plus DRE-based screening.', 'The ANSWER accurately reflects these findings by stating that DRE is a significant barrier to participation and that PSA-alone screening detects more cancers with fewer negative biopsies.'], \"SCORE\": PASS}"
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vllm-0f0446680a864be8ba48d22ea87e67d6 | 23929663 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses the behavior of various autoantibodies in patients with autoimmune hepatitis (AIH) and their association with disease activity and remission.', 'It specifically mentions that ASMA and AAA are significantly associated with biochemical and histological features of disease activity after treatment.', 'The ANSWER states that ASMA and AAA are indirect markers of histological and biochemical activity of AIH, which aligns with the findings in the CONTEXT.', \"The CONTEXT also notes that the autoantibody profile does not markedly vary in the course of AIH, except for ANA, which is consistent with the ANSWER's statement about the persistence of high titers of ASMA and/or AAA being associated with disease activity.\"], \"SCORE\": PASS}"
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vllm-b883e3b35a894cbaa00d3dbe78f947cf | 23800339 | {
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"content": "{\"REASONING\": ['The context describes a study where vaccinated rhesus macaques were exposed to live SHIV challenges and showed significant increases in anti-gp140 Ab titers despite no detectable viremia.', 'The context mentions that anti-Env Ab responses were boosted and altered by the live-virus challenges, leading to the induction of Abs targeting neo-antigens presented by the challenge virus.', 'The answer accurately reflects the findings in the context, stating that anti-Env Ab responses were altered by the live SHIV challenges in the absence of viremia.', \"The answer's mention of 'multiple, live SHIV challenges' and 'no detectable viral loads' directly aligns with the details provided in the context.\"], \"SCORE\": PASS}"
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vllm-198ea43366424c1cb6e0fa013e8340b0 | 9672182 | {
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"content": "{\"REASONING\": ['The context describes hyperplastic foci as hypercellular areas that resemble early hepatocellular carcinoma or adenomatous hyperplasia.', 'It mentions that hyperplastic foci were found in a significant proportion of patients with hepatocellular carcinoma, particularly in those with multiple nodules.', 'The context states that the incidence of hyperplastic foci showed a significant positive correlation with the multiplicity of hepatocellular carcinoma nodules.', 'Immunohistochemical analysis indicated that hyperplastic foci were composed of proliferative hepatocytes similar to adenomatous hyperplasia and early hepatocellular carcinoma.', 'Based on these points, the answer that hyperplastic foci reflect the risk of multicentric hepatocarcinogenesis is supported by the context.'], \"SCORE\": PASS}"
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vllm-0250aead20424bff9b390210d6f014a3 | 20014210 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses a study that tested the predictive value of a restrictive mitral inflow pattern on echocardiography for appropriate ICD therapy in patients who received ICDs for primary prevention.', 'The study found that a restrictive pattern was present in 40.7% of the patients and that appropriate ICD therapy occurred in 11.5% of subjects with a restrictive pattern and 18.4% with a nonrestrictive pattern.', 'The study concluded that the presence of a restrictive pattern was not significant in predicting the time to first ICD therapy.', 'The ANSWER states that severe diastolic dysfunction (which is equivalent to a restrictive mitral inflow pattern) was not helpful in targeting the use of ICDs to those at highest risk, which aligns with the findings in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-c07baef4630c484a8d7b92bc3521faf8 | 9586902 | {
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"content": "{\"REASONING\": ['The context discusses the role of various cytokines, including IL-12, in ovarian cancer.', 'It mentions that high ascitic-fluid concentrations of IL-12 are associated with poor disease-free and overall survival in univariate analyses.', 'The multivariate Cox regression analysis shows that ascitic-fluid IL-12 levels retain independent prognostic significance, along with other factors.', 'The answer states that high ascitic-fluid IL-12 levels are associated with disease progression, which aligns with the context\\'s findings on poor survival outcomes.', 'Therefore, the answer is faithful to the context provided.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes a study examining the effect of TGF-beta3 on myometrial and leiomyoma cells.', 'It mentions that TGF-beta3 stimulation leads to increased production of ECM proteins (collagen 1A1, fibronectin 1, and connective tissue growth factor) in both cell types.', 'The context also notes that TGF-beta3 decreases the production of genes involved in matrix resorption (matrix metalloproteinase 2 and -11).', 'The answer states that TGF-beta3 induces a molecular phenotype in myometrial cells similar to leiomyoma cells, with elevated ECM-related genes and decreased ECM degradation-related genes.', 'This accurately reflects the findings described in the context, making the answer faithful to the context.'], \"SCORE\": PASS}"
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vllm-e8ce30d0a5044da2908486fd2da80560 | 12704355 | {
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"content": "{\"REASONING\": ['The context describes a study that is specifically designed to assess the efficacy and safety of fexofenadine in children with seasonal allergic rhinitis.', 'The study is a randomized, double-blind, placebo-controlled trial involving 935 children aged 6-11 years.', 'The results show that fexofenadine was significantly superior to placebo in reducing symptoms, with a P-value of less than 0.0001.', 'Individual symptom scores, including nasal congestion, showed statistically significant improvement with fexofenadine compared to placebo.', 'There was no significant difference in adverse events between fexofenadine and placebo, indicating that fexofenadine was well-tolerated.', 'The answer accurately reflects the findings of the study, confirming the efficacy and safety of fexofenadine in children with seasonal allergic rhinitis.'], \"SCORE\": PASS}"
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vllm-74499ae78cba4c61af812d21bc208921 | 27647397 | {
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"content": "{\"REASONING\": ['The context describes a study on intratumor heterogeneity in esophageal squamous cell carcinoma (ESCC) using whole-exome sequencing and array-based comparative genomic hybridization.', 'The study involved profiling mutations and copy number changes from 11 regions within 2 cases of ESCC and from metastatic lymph nodes.', 'The results showed significant heterogeneity among different regions within the same tumor, with less than 25% similarity in mutations and less than 20% similarity in gene copy number alterations.', 'Phylogenetic analysis suggested the coexistence of multiple genomic heterogeneous clones within a primary ESCC, and that metastatic subclones may evolve from primary non-metastatic parental clones.', 'The context explicitly states that a single-region sampling cannot reflect the architecture of the genomic landscape of mutations in ESCC tumors.', 'Therefore, the answer that sequence analysis of whole-genome exons in multiple regions can provide strong evidence for genomic heterogeneity in ESCC is faithful to the context.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context indicates that both 30 and 60 minutes of supraceliac aortic cross-clamping (SC AXC) result in the activation of fibrinolytic pathways.', 'The context specifies that tissue plasminogen activator antigen increases during clamping and 5 minutes after clamping for both 30 and 60 minutes of SC AXC.', 'However, the context also notes that tissue plasminogen activator activity increases only in the 60-minute SC AXC group during clamping, 5 minutes, and 30 minutes after unclamping, compared to both control groups.', 'The answer correctly states that while both 30 and 60 minutes of SC AXC lead to activation of fibrinolytic pathways, only 60 minutes of SC AXC induces a fibrinolytic state.', 'Therefore, the answer is faithful to the context as it accurately reflects the findings regarding the duration of SC AXC and its association with the activation of fibrinolytic pathways.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context describes that endotoxin tolerance, heat shock (HS), and heat shock factor 1 (HSF-1) all lead to the down-regulation of innate immunity.', 'It is hypothesized that HSF-1 induces competitive inhibition of nuclear factor-kappaB (NF-kappaB)-induced signal transduction in both endotoxin tolerance and HS.', 'The context mentions that HSF-1 reaches maximum expression 60 to 90 minutes after HS and that endotoxin tolerance, HS, and exposure to HSF-1 inhibit NF-kappaB nuclear binding.', 'The answer states that HSF-1 inhibits NF-kappaB nuclear binding during endotoxin tolerance and HS, which aligns with the information provided in the context.'], \"SCORE\": PASS}"
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vllm-dc6db29d94894b349c76b96edcb8dc39 | 25930174 | {
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vllm-2528ca41d6e94dc9aa546fbf54a6730e | 26747087 | {
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"content": "{\"REASONING\": ['The context indicates that both HDAC5 and HDAC6 were highly expressed in melanoma cells and had low expression levels in normal skin cells.', 'The study found that knocking down either HDAC5 or HDAC6 in A375 cells demonstrated that both contributed to the proliferation and metastasis of melanoma cells.', 'The context does not mention that HDAC5 and HDAC6 were required through different signaling pathways.', 'The answer incorrectly adds the detail about different signaling pathways, which is not supported by the provided context.'], \"SCORE\": FAIL}"
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vllm-9b421b18bcce44588eb4838d34239351 | 24868224 | {
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vllm-e972fbfa67514d7bac6cf3a358fda70e | 22576962 | {
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"content": "{\"REASONING\": ['The context describes a study that investigated the molecular mechanisms responsible for the difference in hypertrophic differentiation between human articular cartilage and growth plate cartilage.', 'The study found that Gremlin 1, Frizzled-related protein (FRP), and Dkk-1 are enriched in articular cartilage and act as inhibitors of hypertrophic differentiation.', 'Pathway analysis showed decreased Wnt signaling in articular cartilage compared to growth plate cartilage, which is partly due to the increased expression of these three proteins.', 'Supplementation of Gremlin 1, FRP, and Dkk-1 diminished terminal hypertrophic differentiation in experimental models.', 'The context also mentions a significant genetic association between a single-nucleotide polymorphism in the GREM1 gene and a reduced risk of radiographic hip OA.', 'Based on these findings, the answer correctly identifies Gremlin 1, FRP, and Dkk-1 as key regulators of human articular cartilage homeostasis and suggests their potential role in therapeutic interventions for OA.'], \"SCORE\": PASS}"
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vllm-630e98da06364d21b0789d10604416af | 10210641 | {
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"content": "{\"REASONING\": ['The context describes an experiment where postnatal booster injections were given to mice after in utero stem cell transplantation.', 'The results showed a significant increase in donor cell engraftment in the postnatally boosted animals compared to the control animals.', 'The answer accurately reflects the findings from the context, stating that postnatal booster injections increase donor cell engraftment.', 'The answer also correctly interprets the hypothesis and suggests that postnatal booster injections may be a viable therapeutic strategy, which is consistent with the context.'], \"SCORE\": PASS}"
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vllm-c7456fe7c5b04df5afb802675fdb7148 | 26683568 | {
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"content": "{\"REASONING\": ['The CONTEXT states that the long-term analysis of the KOOS assessment shows no significant association between the time of day of surgery and the level of surgeon experience.', 'The CONTEXT also mentions that there was no difference in complication rates between the time of day of surgery and the level of surgeon experience.', 'The ANSWER correctly reflects these findings by stating that complication rates and KOOS outcome after surgery were not influenced by time of day of surgery and experience level of the surgeon.', 'The CONTEXT does note an increased risk for longer hospital stays in certain scenarios, but this is not directly related to the long-term outcome or complication rates, which is what the QUESTION is asking about.'], \"SCORE\": PASS}"
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vllm-e20eb08dda3d4e798d1bca5e72fcb03b | 8466068 | {
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"content": "{\"REASONING\": ['The context describes a study where insulin was administered to patients during the anhepatic stage of liver transplantation.', 'The study found that in the treatment group, serum potassium concentrations decreased significantly within 15 minutes and 60 minutes after insulin administration, compared to the control group.', 'The context provides specific data showing the decrease in potassium concentrations in the treatment group, indicating that insulin was effective in decreasing serum potassium levels.', 'The answer accurately reflects the findings of the study, stating that insulin rapidly decreases serum potassium concentration, even in the absence of the liver.'], \"SCORE\": PASS}"
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vllm-a7f15fa0480646b598a8a959325b8a5b | 15572021 | {
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"content": "{\"REASONING\": ['The context mentions that there were statistically significant correlations between general knowledge about risk factors for CHD and compliance to certain lifestyle changes.', 'These lifestyle changes include weight, physical activity, stress management, diet, attainment of lipid level goals, and the likelihood of taking prescribed blood pressure-lowering drugs.', 'The context also notes that general knowledge of risk factors had no correlation to blood glucose or blood pressure levels nor on smoking habits or treatment patterns for prescribed lipid- and blood glucose-lowering drugs.', 'The answer states that knowledge correlates to patient behavior with respect to some risk factors, which aligns with the context that specifies certain areas where knowledge had a significant impact.', 'Therefore, the answer is faithful to the context as it accurately reflects the findings mentioned.'], \"SCORE\": PASS}"
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vllm-d569ccddf62d46a789abb46d15077144 | 11724198 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study on indicators nurses use to decide whether to test healthy full-term newborns for total serum bilirubin.', 'The study found that the presence of jaundice and feeding frequency are predictive variables for nurse-driven total serum bilirubin testing.', 'The odds ratio (OR) for the presence of jaundice is 31.95, indicating a strong association with the decision to test.', 'The OR for feeding frequency is 0.28, indicating that nurses who assess feeding frequency are less likely to order bilirubin testing.', 'The ANSWER accurately reflects these findings by stating that the presence of jaundice and feeding frequency are indicators used by nurses and that nurses who assess feeding frequency are less likely to order the test.', \"The ANSWER also mentions that newborns are overtested for bilirubin, which is supported by the CONTEXT's statement that 91% of newborns tested for bilirubin were tested unnecessarily.\"], \"SCORE\": PASS}"
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vllm-f9dfaa927b0d468ea69ea79e1ed8320b | 26814527 | {
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"content": "{\"REASONING\": ['The CONTEXT indicates that brain injury was the most likely cause of death in all hourly intervals, but hemorrhage was as or more important than brain injury as the cause of death during the first 3 hours and up to 6 hours.', 'The ANSWER states that hemorrhage is more prevalent than brain injury in early trauma deaths, which is not fully supported by the CONTEXT. The CONTEXT only mentions that hemorrhage was as or more important than brain injury during specific time intervals, not overall.', 'The CONTEXT also notes that no deaths were attributable to hemorrhage after 12 hours, which is not reflected in the ANSWER.', 'Therefore, the ANSWER does not accurately represent the detailed information provided in the CONTEXT.'], \"SCORE\": FAIL}"
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vllm-ffa84cf3e0ff4577b582bfa25cbc28db | 26670667 | {
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"content": "{\"REASONING\": ['The context states that inflammatory cytokines can induce both apoptosis and autophagy in MSCs.', 'It is mentioned that inhibiting autophagy in MSCs increases the survival rate of septic mice, implying that autophagy promotes apoptosis.', 'The context explicitly states that autophagy promotes apoptosis of MSCs during application to septic mice.', 'Further study showed that autophagy aggravates tumor necrosis factor alpha plus interferon gamma-induced apoptosis of MSCs.', 'The mechanism involves autophagy inhibiting the pro-survival gene Bcl-2, leading to increased apoptosis.', 'Therefore, the answer that autophagy promotes apoptosis of MSCs in an inflammatory microenvironment is supported by the context.'], \"SCORE\": PASS}"
},
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vllm-6c6a1764b3f041898144870b48501f02 | 15839968 | {
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"content": "{\"REASONING\": ['The context describes a study comparing outcomes between patients who had a contrast study prior to ileostomy closure and those who did not.', 'The study included patients with a straight colorectal/coloanal anastomosis that could be examined clinically and had a smooth postoperative course with no evidence of pelvic sepsis.', 'The results showed no cases of pelvic sepsis after ileostomy reversal in any patient, regardless of whether they had a contrast study or not.', 'The answer states that a radiological examination of the anastomosis prior to ileostomy closure appears unnecessary in patients with a clinically examinable anastomosis and a smooth postoperative course, which aligns with the findings in the context.'], \"SCORE\": PASS}"
},
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vllm-47b999c1778d4c4bb8f1c3c3766169d2 | 20731863 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study on the genetic differentiation of Atlantic molly populations in the Cueva del Azufre system before and after a catastrophic flood event.', 'The study found that habitat type, not geographic distance, was the major predictor of genetic differentiation, and each habitat type harbored a genetically distinct population both before and after the flood.', 'The CONTEXT mentions a weak signal of individual dislocation among ecologically divergent habitat types, but significant dislocation within the same habitat type.', 'The ANSWER states that locally adapted fish populations maintain small-scale genetic differentiation despite the perturbation by the flood event, which aligns with the CONTEXT findings that genetic differentiation was maintained across different habitat types.', 'The ANSWER also mentions strong natural selection against migrants, which is supported by the CONTEXT indicating a weak signal of individual dislocation among ecologically different habitat types.'], \"SCORE\": PASS}"
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vllm-1d7ba079c23c4c6c85ccccef8f68727f | 20602543 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context states that elevated NLR is linked with worse survival in many malignancies, but its association with pancreatic cancer (PC) remains unclear.', 'The study reviewed 95 patients with advanced PC and found that elevated pretreatment NLR (> 5) was an independent prognostic factor for overall survival (OS).', 'The median OS for patients with elevated NLR was 2.4 months compared to 7.7 months for those with normal NLR, indicating a significant difference (p < 0.001).', 'Based on these findings, the answer that elevated NLR is a predictor of shorter survival in patients with advanced PC is supported by the context.'], \"SCORE\": PASS}"
},
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vllm-2107c633530a4b49945b3b1d21462a10 | 12665491 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context describes increased expression of Mac-1 (CD11b/CD18) in association with neointimal hyperplasia after coronary interventions.', 'It mentions that the role of Mac-1 in restenosis is incompletely defined, but the study aimed to clarify this by determining if coronary stenting induced Mac-1 activation.', 'The study found significant increases in CD11b expression and 8B2 binding (indicating Mac-1 activation) in patients undergoing coronary stenting, particularly in those with subsequent restenosis.', 'Multiple regression analysis showed that late lumen loss was independently correlated with CD11b and 8B2 increases, with Mac-1 activation being the most powerful predictor of late lumen loss.', 'The answer accurately reflects these findings by stating that coronary stenting produced upregulation and early activation of Mac-1, which is associated with late lumen loss and restenosis.'], \"SCORE\": PASS}"
},
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vllm-7d868021e69a4610af72a1ee5074586e | 17932889 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context describes a study that tested the effectiveness of pimecrolimus and dual pimecrolimus-paclitaxel eluting stents in a porcine model.', 'The study had two phases: the first phase tested pimecrolimus-eluting stents and the second phase tested dual pimecrolimus-paclitaxel eluting stents.', 'In the first phase, it was found that neointimal proliferation was significantly less in the pimecrolimus fast release group compared to the bare metal controls.', 'In the second phase, neointimal proliferation was significantly less in the dual drug group compared to the bare metal controls.', 'The answer correctly states that pimecrolimus inhibits neointimal proliferation and that the dual drug eluting stent concept was established, showing both safety and efficacy.'], \"SCORE\": PASS}"
},
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vllm-abe8b919675849a190d2109501623470 | 25886616 | {
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"created": 1719619525,
"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context describes EVI1 as a transcription factor that regulates various cellular processes and contributes to the aggressiveness of certain malignancies.', 'It mentions that the study aimed to identify novel EVI1 target genes in human myeloid cells.', 'The context specifically identifies MS4A3 as the most strongly repressed gene in response to EVI1 induction.', 'It confirms that EVI1 regulates MS4A3 through direct binding to a promoter proximal region using reporter gene assays and chromatin immunoprecipitation.', 'The context also states that re-expression of MS4A3 in an EVI1 overexpressing cell line counteracted the tumor-promoting effect of EVI1 by increasing apoptosis.', 'Therefore, the answer that EVI1 promotes tumor growth via transcriptional repression of MS4A3 is supported by the context.'], \"SCORE\": PASS}"
},
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vllm-669d74b4f48945ceb2cfeaf0efcda587 | 24836459 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The CONTEXT indicates that CDX1 restricts trophoblast cell invasiveness and reduces MMP-9 expression.', 'The CONTEXT also states that CDX1 does not affect PI3K/AKT signaling in HTR-8/SVneo trophoblast cells.', 'The ANSWER correctly states that CDX1 restricts the invasion of HTR-8/SVneo trophoblast cells by inhibiting MMP-9 expression.', 'However, the ANSWER contradicts the CONTEXT by saying that CDX1 functions in concert with PI3K/AKT signaling to regulate trophoblast invasion, which is not supported by the CONTEXT.'], \"SCORE\": FAIL}"
},
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],
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vllm-d3e9e9405a9a4d7b9af1ea6193d4639c | 20179671 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT describes the effects of Ob-X on adipose tissue growth in obese mice.', 'It mentions that Ob-X inhibited angiogenesis and MMP activity, leading to significant reductions in body weight gain and adipose tissue mass.', 'The CONTEXT also specifies that the mass of both visceral and subcutaneous fat was reduced, and the size of adipocytes was significantly reduced in Ob-X-treated mice.', 'Additionally, the CONTEXT notes that Ob-X treatment decreased blood vessel density and MMP activity in visceral adipose tissues and altered the mRNA levels of angiogenic factors and MMPs.', 'The ANSWER accurately reflects these findings by stating that Ob-X reduces adipose tissue mass and suggests that this reduction is related to the inhibition of angiogenesis, which is consistent with the CONTEXT.'], \"SCORE\": PASS}"
},
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"finish_reason": "stop",
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vllm-074e66d62a6e4160b4b2dbc867f16fcc | 22238509 | {
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"content": "{\"REASONING\": ['The context describes a study where oxaliplatin (OXA) was encapsulated in chitosan vesicles (CSO-SA micelles) to target both cancer stem-like cells (CSLCs) and bulk cancer cells in colorectal cancer (CRC).', 'The study found that CSO-SA/OXA micelles showed excellent internalization ability, increasing OXA accumulation in CRC cells and tissues.', 'The micelles increased the cytotoxicity of OXA against bulk cancer cells and reversed chemoresistance in CSLC subpopulations in vitro.', 'In vivo, intravenous administration of CSO-SA/OXA micelles effectively suppressed tumor growth and reduced CD133+/CD24+ cell populations (putative CRC CSLC markers) compared to free OXA treatment.', 'The results suggest that CSO-SA/OXA micelles are effective in eliminating both CSLCs and bulk cancer cells, supporting the answer that they can eradicate CSLCs and may be a new option for CRC therapy.'], \"SCORE\": PASS}"
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vllm-8dcee942b1a34ce6b867fd783071729d | 24637128 | {
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"content": "{\"REASONING\": ['The context discusses the relationship between olfactory dysfunction and cardiovascular dysautonomia in early-stage Parkinson\\'s disease (PD) patients.', 'It mentions that olfactory dysfunction is considered to precede motor symptoms in PD, while the timing of cardiovascular dysautonomia is not well understood.', 'The study evaluated the relationship between olfactory dysfunction and various cardiovascular autonomic tests, finding correlations between olfactory scores and certain cardiovascular metrics.', 'The context provides specific statistical results showing correlations between olfactory scores and cardiovascular measures, such as blood pressure responses to norepinephrine and dobutamine infusions, cardiac MIBG uptake, and pressure recovery time during the Valsalva maneuver.', 'The answer summarizes these findings by stating that both the cardiovascular sympathetic system and the olfactory system are impaired in the early stage of PD, suggesting concurrent degeneration during the premotor phase.'], \"SCORE\": PASS}"
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vllm-31f094184ebe40f393a0a3dba08045f4 | 27287412 | {
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"content": "{\"REASONING\": ['The context describes a study that investigates the role of IL-6 secreted from CAFs in modulating chemoresistance in NSCLC cells.', 'It is mentioned that IL-6 significantly increased transforming growth factor-β1-induced epithelial-to-mesenchymal transition (EMT) changes in cancer cells.', 'The conditioned media from CAFs induced EMT and resistance to cisplatin in NSCLC cells through IL-6 signaling.', 'Immunohistochemical analysis showed that stromal IL-6 expression was correlated with EMT changes in cancer cells.', 'Therefore, the answer stating that IL-6 from CAFs enhanced EMT in NSCLC cells and may contribute to chemoresistance is consistent with the findings presented in the context.'], \"SCORE\": PASS}"
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"content": "{\"REASONING\": ['The context provides data on readmittance rates within 30 days, but it does not specifically focus on or support a seven-day observation period.', 'The context mentions that the median time until readmission for preventable cases is two and four and a half days, which suggests that a shorter observation period might be more relevant for patient safety.', 'The context does not provide a direct comparison or analysis of seven-day readmittance rates versus other time periods, making it unclear why a seven-day period is specifically recommended.', 'The answer extrapolates a specific recommendation (seven-day observation period) that is not directly supported by the data or analysis provided in the context.'], \"SCORE\": FAIL}"
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"content": "{\"REASONING\": ['The CONTEXT describes how the p65(RelA) homodimer binds to different DNA sequences, including asymmetric and pseudosymmetric sequences.', 'It mentions that the global positioning of the dimer on both DNA targets is roughly symmetric, but the hydrogen-bonding patterns at the protein-DNA interfaces differ significantly.', 'The CONTEXT also notes that one of the p65 monomers in complex with the asymmetric DNA binds to an extra base pair located immediately upstream of the 5\\'-GGAA-3\\' half site.', 'The ANSWER states that p65 exhibits the unique capability to specifically bind DNA targets of variable lengths from four to ten base pairs, which is not directly supported by the CONTEXT.', 'The ANSWER also mentions the role of the small protein segment Arg41-Ser42-Ala43 in flexibility in DNA-binding modes, which is not mentioned in the CONTEXT.', 'Therefore, the ANSWER does not accurately reflect the specific details provided in the CONTEXT about how p65 recognizes DNA targets.'], \"SCORE\": FAIL}"
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vllm-763da9446af645968520eccb8be0f785 | 16565759 | {
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"content": "{\"REASONING\": ['The context describes the isolation and culture of human limbal epithelial cells and the analysis of various markers to determine their characteristics.', 'The context mentions that the transcription levels of K3 and K12 in cultured cells were lower than in freshly isolated limbal cells or cells from the central cornea, indicating some changes in the cells during culture.', 'The context also notes that few cells were positive for K3 in primary or secondary cultures, and staining for K3 remained sparse even after airlifting, suggesting that the cells did not maintain strong characteristics of limbal stem or progenitor cells.', 'The context does show that the cells were able to proliferate and form multiple layers, and some markers like PCNA and p63 were expressed, but this does not necessarily mean that the cells maintained all characteristics of limbal progenitor cells.', 'Therefore, the answer stating that human limbal cells maintained characteristics similar to limbal stem or progenitor cells is not fully supported by the context.'], \"SCORE\": FAIL}"
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vllm-747b07c86a19437f8bbd0c1d8d71253d | 15564772 | {
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"content": "{\"REASONING\": ['The context describes the human histamine H1 receptor as constitutively active, leading to basal activation of NF-kappaB.', 'It mentions that certain H1 antihistamines, including desloratadine, inhibit basal NF-kappaB activity by stabilizing the H1 receptor in an inactive state, which is characteristic of inverse agonism.', 'The context provides specific data showing that desloratadine reduces basal NF-kappaB activity and blocks histamine-stimulated NF-kappaB activity, with a high rank order of potency.', 'The answer accurately reflects the information in the context by stating that desloratadine inhibits basal and histamine-stimulated NF-kappaB activity, consistent with its classification as an inverse agonist at the histamine H1 receptor.'], \"SCORE\": PASS}"
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vllm-ff52252479d34b7f81e80703720f7932 | 9672797 | {
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"content": "{\"REASONING\": ['The context describes the use of indocyanine green angiography in diagnosing central serous chorioretinopathy (CSC) and mentions its value in identifying transient choroidal hyperfluorescence, which is characteristic of CSC.', 'The context specifies that transient indocyanine green hyperfluorescence was seen in all eyes with CSC, both typical and chronic, and was seldom seen in occult choroidal neovascularization due to age-related macular degeneration.', 'The context also notes that most patients with chronic serous chorioretinopathy presented multizonal transient choroidal hyperfluorescence in both eyes on indocyanine green angiography.', 'The answer correctly states that transient choroidal hyperfluorescence is suggestive of chronic central serous chorioretinopathy in older patients presenting retinal pigmentary disease with fluorescein leakage of undetermined source.', 'The answer also mentions that chronic central serous chorioretinopathy is not uncommonly associated with classic choroidal neovascularization in the elderly, which is supported by the context that found four classic choroidal neovascular membranes in 12 eyes.'], \"SCORE\": PASS}"
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vllm-ababe42ea52e4bbcaaec0586a88c639d | 27122334 | {
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"content": "{\"REASONING\": ['The CONTEXT describes an experiment where different decontaminants (water, 75% ethanol, PEG400, and Diphoterine) were applied to phenol burn wounds in rats.', 'The CONTEXT states that the Diphoterine group had a significantly better effect and significantly lower degrees of skin and organ injuries compared to the water group.', 'The CONTEXT also mentions that the water group had the worst effect, the deepest wounds, and the most severe organ injuries.', 'The ANSWER correctly reflects that early decontamination with water has a poor effect and that Diphoterine can reduce the depth of phenol burns and the degrees of injuries of vital organs, and has a good effect of decontamination.'], \"SCORE\": PASS}"
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vllm-c38dd723d81f40259b0e3c4e27acbfa0 | 22545885 | {
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"content": "{\"REASONING\": ['The context provides a systematic review and meta-regression of various thresholds for intervention in isolated type II endoleak after EVAR.', 'The study analyzed 10 series with 231 patients and found that the majority (84.0%) had stable or shrinking sacs during follow-up, with no ruptures occurring.', 'Meta-regression showed no evidence that aggressive or selective strategies reduced sac expansion or improved sac regression compared to a conservative approach.', 'The answer accurately reflects the findings by stating that there is inadequate information to support any one threshold for intervention.', 'The answer also correctly notes the benign nature of isolated type II endoleak and the need for prospective data to devise an optimal management algorithm.'], \"SCORE\": PASS}"
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vllm-322cf22e595e462884ce0a9e58ce2b11 | 27249091 | {
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"content": "{\"REASONING\": ['The context provides data on the impact of childhood trauma on the psychopathological profile of patients with early psychosis, categorized by the age of exposure.', 'It states that patients with early trauma (before 12 years of age) showed consistently higher levels of positive, depressive, manic, and negative symptoms compared to nontrauma patients.', 'Patients with late trauma (from age 12 through 16 years) showed only more negative symptoms compared to nontrauma patients.', 'This information indicates that the age at which trauma is experienced modulates the psychopathological profile in patients with early psychosis.', 'The answer accurately reflects the findings in the context, suggesting that the age of exposure to trauma does influence the symptoms observed in these patients.'], \"SCORE\": PASS}"
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vllm-b65411b3876c49d0b460e12ed5f94888 | 25375979 | {
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"content": "{\"REASONING\": ['The context indicates that TNF-α increased cortisol and GH levels in healthy controls (CTR) but not in hypopituitary patients (HP).', 'The context also shows that TNF-α increased phenylalanine fluxes and urea flux in CTR more significantly than in HP, and elevated endogenous glucose production (EGP) in CTR compared to HP.', 'The context suggests that the metabolic response to TNF-α, including increases in urea and amino acid fluxes and EGP, is more pronounced in CTR than in HP, implying a role for intact pituitary function in this response.', 'Therefore, the answer stating that intact pituitary function is decisive for the catabolic response to TNF-α is supported by the context.'], \"SCORE\": PASS}"
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vllm-7d2988d7c0c34a33901c2cb0e7f24836 | 22095239 | {
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{
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"content": "{\"REASONING\": ['The context discusses a study examining whether common variation in oxidative phosphorylation (OxPhos) genes contributes to type 2 diabetes susceptibility or influences diabetes-related metabolic traits.', 'The study found some nominal associations between OxPhos gene variants and type 2 diabetes, but these associations did not remain robust after correction for multiple testing.', 'The context also mentions that none of the investigated variants negatively influenced surrogate markers of insulin sensitivity in non-diabetic participants, and only a few variants showed a weak negative influence on indices of glucose-stimulated insulin secretion.', 'The answer accurately reflects the findings from the context, stating that common variation in proximity to the examined OxPhos genes is not a major cause of insulin resistance or type 2 diabetes, while leaving open the possibility that such variants may influence beta cell function in non-diabetic individuals.'], \"SCORE\": PASS}"
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vllm-0357523592c349e8b16671f65fee038c | 11271094 | {
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"content": "{\"REASONING\": ['The context provides detailed information about a study on hypothermia patients admitted to the ICU.', 'The study involved 81 patients and analyzed various factors including the location where hypothermia occurred (indoors or outdoors).', 'The context mentions that stepwise logistic regression identified two variables predictive of death: illness severity at admission (SAPS II >= 40) and the location where hypothermia occurred (indoors versus outdoors).', 'This indicates that patients who developed hypothermia indoors had a worse outcome compared to those who developed it outdoors.', \"The answer states that patients found indoors were more severely affected and died more frequently than those found outdoors, which aligns with the findings presented in the context.\"], \"SCORE\": PASS}"
},
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vllm-50b7b6a758624ecba62d3fb9f11b3ff3 | 19247169 | {
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"content": "{\"REASONING\": ['The CONTEXT describes an in vitro biomechanical study comparing the stability provided by halo-vest and odontoid screw fixation for Type II dens fracture.', 'The study found that the combination of halo-vest and dens screw provided significant reductions in motion at C0/1 and C1/2, with the smallest average percentages of intact motion.', 'The ANSWER states that the reduction in C1/2 motion observed due to the halo-vest and dens screw combined is similar to previously reported immobilization provided by other fixation systems.', 'The CONTEXT does not provide any information about previous studies or comparisons to other fixation systems like polyaxial screw/rod or transarticular screw fixation combined with wiring.', 'Therefore, the ANSWER introduces information not present in the CONTEXT, making it NOT FAITHFUL.'], \"SCORE\": FAIL}"
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vllm-7e0c9047958f42a3ae283de37d95ae60 | 26248649 | {
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"model": "llama-3-70b",
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{
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"message": {
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"content": "{\"REASONING\": ['The context describes a study on miRNA expression profiles in clear cell renal cell carcinomas (ccRCC) and matched normal kidney tissues.', 'It specifically mentions that miR-200c was commonly downregulated in ccRCC specimens and cell lines, and its overexpression suppressed cell growth and induced cell-cycle arrest.', 'Bioinformatics identified cyclin-dependent kinase 2 (CDK2) as a potential target of miR-200c, which was validated using a luciferase reporter assay.', 'Mechanistic investigations revealed that miR-200c directly suppressed the expression of CDK2 in ccRCC cell lines and xenografts.', 'The context concludes that miR-200c plays an antioncogenic role in ccRCC by controlling cell growth and cell-cycle progression by downregulating CDK2.', 'The answer accurately reflects the findings from the context, stating that miR-200c exerts an antioncogenic function in renal cell carcinoma by controlling CDK2-dependent cell growth and cell-cycle progression.'], \"SCORE\": PASS}"
},
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vllm-b4b21cd5220e4b0f83f865c6b15b2c73 | 17082491 | {
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"model": "llama-3-70b",
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{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context discusses the role of Nox1 and Nox4 in maintaining the differentiated phenotype of vascular smooth muscle cells (VSMCs).', 'It mentions that Nox4 and differentiation marker genes were downregulated from passage 1 to passage 6 to 12, suggesting a link between Nox4 and differentiation.', 'Nox4 co-localized with differentiation markers in differentiated VSMCs and moved to focal adhesions in de-differentiated cells, indicating its involvement in maintaining differentiation.', 'siRNA against Nox4 reduced NADPH-driven superoxide production and downregulated differentiation markers, further supporting the importance of Nox4 in maintaining differentiation.', 'The context also notes that Nox1 depletion did not decrease these parameters, indicating that Nox4 is specifically required for maintaining the differentiated phenotype.', 'Therefore, the answer stating that Nox4-derived ROS are critical to the maintenance of the differentiated phenotype of VSMCs is supported by the context.'], \"SCORE\": PASS}"
},
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vllm-bc63e8b671954b33925e6e04e5ac447b | 19460157 | {
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"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context mentions that no clinical or laboratory tests are available to predict response to anti-TNF therapies, indicating a lack of existing predictive methods.', 'The context then describes a study that identified a 24-biomarker signature which enabled prediction of a positive clinical response to etanercept with specific positive and negative predictive values.', 'The answer states that a multi-parameter protein biomarker was identified for pretreatment classification and prediction of etanercept responders, which aligns with the context.', 'The answer also notes that further validation is needed, which is a reasonable extension based on the context.'], \"SCORE\": PASS}"
},
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"completion_tokens": 132
}
} | null |
vllm-09e82f2c8e0c446b9f0bdcc102ad6d45 | 15897483 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The CONTEXT provides data on gastric emptying times and ghrelin levels in both obese and lean subjects.', 'It states that gastric half-emptying time is significantly shorter in obese subjects compared to lean controls.', 'Ghrelin levels are significantly lower in obese subjects compared to lean subjects.', 'A negative correlation between gastric emptying and fasting ghrelin levels is observed only in lean subjects, not in obese subjects.', 'In lean subjects, ghrelin is the only significant independent determinant of gastric emptying, explaining 98% of the variance.', 'The ANSWER correctly summarizes that ghrelin does not influence gastric emptying in obese subjects, as this influence is lost in obesity.'], \"SCORE\": PASS}"
},
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vllm-75521d8b19c44aa88ab4bd5d1e257668 | 23193908 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context describes an experiment where simulated intubation forces were applied to cadaveric human larynges to assess the likelihood of arytenoid dislocation.', 'The experiment involved using an endotracheal tube tip probe (ETTP) and a non-slip probe (NSP) to apply increasing pressure to the arytenoid complexes.', 'The results showed that none of the trials disrupted the cricoarytenoid joint ligaments, and the joint never appeared to be dislocated, even when forces up to 5 kg were applied.', 'The mean maximal forces measured were 1.8 kg for the ETTP and 4.7 kg for the NSP, indicating that the forces required to cause dislocation were not achieved.', 'The answer accurately reflects the findings of the experiment, stating that arytenoid dislocation did not occur and that endotracheal tube insertion is unlikely to cause arytenoid dislocation.'], \"SCORE\": PASS}"
},
"logprobs": null,
"finish_reason": "stop",
"stop_reason": null
}
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"usage": {
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"completion_tokens": 204
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vllm-193f4d2a89ee4f638e8851b8720212c7 | 12359973 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
"role": "assistant",
"content": "{\"REASONING\": ['The context provides data from a study on prepubertal children that examines the relationship between birth weight and capillary recruitment, while considering blood pressure and insulin sensitivity.', 'The study found a significant positive association between birth weight and capillary recruitment.', 'It also found no significant association between birth weight and insulin sensitivity or systolic blood pressure.', 'The association between low birth weight and impaired capillary recruitment remained unchanged after adjusting for blood pressure and insulin sensitivity.', 'These findings support the hypothesis that the association between birth weight and capillary recruitment is independent of blood pressure and insulin sensitivity.', \"Therefore, the answer 'yes' is faithful to the context provided.\"], \"SCORE\": PASS}"
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vllm-b0e95b47e8db4c0289bd553bf786e89c | 25058883 | {
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"content": "{\"REASONING\": ['The context states that the study aimed to investigate risk factors for acute kidney injury (AKI) in patients with acute pancreatitis (AP).', 'The study found that hypertriglyceridemia was a risk factor for AKI in AP, with a specific odds ratio and confidence interval provided.', 'The context mentions that 42 patients developed AKI within the first 48 hours, indicating that the study focused on the early phase of AP.', 'The answer correctly identifies hypertriglyceridemia as an independent risk factor for AKI in the early phase of AP.', 'The additional information in the answer about obesity and mortality is consistent with the context, which provides mortality rates for different weight groups.', 'The hypothesis about pancreatic enzymes and triglyceride accumulation in the renal system is a plausible explanation based on the context and supports the answer.'], \"SCORE\": PASS}"
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vllm-3363918b44ca43089cc3605f4441caac | 21346095 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study examining the relationships between testosterone, estradiol, muscle mass, muscle strength, and physical performance in older men.', 'It mentions that appendicular skeletal mass (ASM) was positively associated with total testosterone, free testosterone, and total estradiol, but not with free estradiol.', 'After adjustments, both total testosterone and free testosterone were significantly associated with grip strength, narrow-walk speed, and the composite neuromuscular score.', 'Higher total estradiol was associated with lower grip strength after adjustments.', 'The ANSWER states that testosterone level was related to muscle mass, strength, and physical performance, and that total estradiol level, while related to muscle mass positively, affected muscle strength adversely in older men.', 'The ANSWER accurately reflects the findings presented in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-367478d1286146339d8db4089f38de34 | 23088972 | {
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"content": "{\"REASONING\": ['The CONTEXT provides detailed information about a study investigating the relationship between the eNOS4a/b polymorphism and clinical features of superficial bladder cancer.', 'The study found that the aa genotype was significantly more common in patients with superficial bladder cancer and that the aa plus ab genotype was associated with high-grade tumors and progression to muscle-invasive disease.', 'The CONTEXT also mentions that the aa plus ab genotype was a significant independent risk factor for recurrence after adjusting for various factors.', 'The ANSWER accurately reflects these findings by stating that a genotype containing the a allele may be a risk factor for bladder cancer and that patients with the aa plus ab genotype are more likely to experience tumor recurrence and progression.'], \"SCORE\": PASS}"
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vllm-2469f64a67ab4600876f084e8c535f97 | 26962854 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a study that investigates the changes in HDL-associated miRNAs, including miR-223, after diet-induced weight loss in overweight and obese males.', 'The study found that the high protein (HP) diet induced a significant decrease in HDL-associated miR-223 levels (p = 0.015).', 'The ANSWER correctly states that HDL-associated miR-223 levels are significantly decreased after HP diet-induced weight loss in overweight and obese males.', 'The ANSWER also mentions that this is the first study reporting changes in HDL-associated miRNA levels with diet-induced weight loss, which is consistent with the CONTEXT stating that the regulation of HDL-associated miRNAs after diet-induced weight loss has not been studied before.'], \"SCORE\": PASS}"
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vllm-6987e9f16663461dbf9009f9d07cee69 | 19751814 | {
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"content": "{\"REASONING\": ['The context describes the antispasmodic, antidiarrheal, bronchodilatory, and tracheo-relaxant activities of Artemisia vulgaris.', 'It mentions that the crude extract of Artemisia vulgaris (Av.Cr) caused concentration-dependent relaxation of jejunum spontaneous contractions and inhibited carbachol (CCh) and K(+)-induced contractions.', 'The context also states that Av.Cr shifted the Ca(2+) concentration-response curves to the right, similar to verapamil and dicyclomine, indicating calcium channel blockade.', 'Additionally, Av.Cr produced a rightward parallel shift in CCh-curves, followed by a non-parallel shift at higher concentrations with suppression of the maximum response, similar to dicyclomine, indicating muscarinic receptor blockade.', 'The context further mentions that Av.Cr exhibited protective effects against castor oil-induced diarrhea and CCh-mediated bronchoconstriction in rodents, and relaxed CCh and K(+)-induced contractions in trachea, shifting the CCh-curves to the right.', 'The answer summarizes these findings by stating that Artemisia vulgaris exhibits a combination of anticholinergic (muscarinic receptor blockade) and Ca(2+) antagonist mechanisms, which aligns with the context provided.'], \"SCORE\": PASS}"
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vllm-62fd2587cccd4ec3930d457f2e3a0e2e | 16314597 | {
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"content": "{\"REASONING\": ['The CONTEXT discusses a study comparing IEI and SFD subjects, finding that more than half of the IEI subjects met the criteria for SFD.', 'The CONTEXT mentions that IEI subjects shared symptoms and psychological features of somatization with the SFD group.', 'The CONTEXT also notes that IEI subjects who did not fulfill SFD criteria still had higher symptom scores, higher trait anxiety, and more pronounced somatic symptom attributions compared to nonsomatoform controls.', 'The CONTEXT concludes that psychological features were significantly associated with the burden of somatic symptoms in both SFD and IEI.', 'The ANSWER states that the similarity of IEI and SFD regarding symptoms and psychological features supports the hypothesis that IEI is a variant of SFD.', 'The ANSWER is faithful to the CONTEXT because it accurately reflects the findings and conclusions presented in the CONTEXT, which suggest a strong overlap between IEI and SFD.'], \"SCORE\": PASS}"
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vllm-198f2a8551eb4696ade7f73cd3219829 | 16368648 | {
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"content": "{\"REASONING\": ['The context indicates that higher basal levels of GRP94 protein are associated with lower sensitivity to X-ray irradiation in some cervical cancer cell lines, specifically HeLa and QG-U cells.', 'The context also mentions that reducing GRP94 protein levels in HeLa cells increased their sensitivity to X-ray irradiation, suggesting that GRP94 contributes to radio-resistance.', 'The answer accurately reflects these findings by stating that high basal protein levels of GRP94 are correlated with a modest decrease in sensitivity to X-ray cell death and suggests that GRP94 siRNA might be useful in reversing radio-resistance.', \"The context does not provide evidence that GRP94 siRNA would be effective in all cervical cancer cell lines, as it had little effect on X-ray sensitivity in Caski cells. The answer acknowledges this by specifying 'some cervical cancer cell lines' and 'modest decrease in sensitivity,' which aligns with the context's findings.\"], \"SCORE\": PASS}"
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vllm-b152f56f9f044243b1d522739517f4e4 | 26274822 | {
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"content": "{\"REASONING\": ['The CONTEXT describes how hypoxia and acidosis affect cellular metabolism and protein synthesis in vitro.', 'It mentions that acidosis suppresses overall ATP turnover and protein synthesis by 50%, while hypoxia suppresses protein synthesis but not total ATP production.', 'The CONTEXT also states that a dramatic decrease in ATP turnover and protein synthesis is observed when hypoxia and low pH are combined.', 'The ANSWER correctly summarizes that hypoxia and acidosis suppress overall metabolic rate and protein synthesis, especially when combined.', 'The ANSWER also highlights the importance of considering these factors in in vivo studies, which aligns with the CONTEXT.'], \"SCORE\": PASS}"
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vllm-f3ccc60ea5d8402c82ea9073956e598a | 25680823 | {
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"content": "{\"REASONING\": ['The context provides data from a study investigating the effect of prophylactic antibiotics (PRO) on the incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management (TTM).', 'The study found that PRO patients had a significantly lower incidence of pneumonia compared to no-PRO patients (12.6% vs. 54.9%, p < 0.001).', 'The context also mentions that PRO were independently associated with a lower incidence of pneumonia (OR 0.09, 95% CI 0.06-0.14, p < 0.001) as determined by backwards stepwise logistic regression.', 'The answer correctly states that prophylactic antibiotics were associated with a reduced incidence of pneumonia.', 'The context also notes that the incidence of good functional outcome was similar between PRO and no-PRO groups (41.1 vs. 36.6%, p = 0.19), which is accurately reflected in the answer stating that the rate of good functional outcome was similar.'], \"SCORE\": PASS}"
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vllm-440d7ec3edd141678405bb77fb9d156b | 10918163 | {
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"content": "{\"REASONING\": ['The context describes a study that assessed the expression of MIF protein and mRNA in lung adenocarcinomas and its relation to patient prognosis.', 'The study found that MIF protein was observed in the nuclei of tumor cells in 79.7% of patients and not in the nuclei of tumor cells in 20.3% of patients.', 'The prognosis was significantly worse for patients without nuclear MIF expression compared to those with MIF expression in the nuclei (P = 0.04).', 'This suggests that the intracellular distribution of MIF, specifically its presence in the nuclei of tumor cells, is associated with a better prognosis.', 'Therefore, the answer stating that intracellular MIF distribution predicts patient prognosis is supported by the findings in the context.'], \"SCORE\": PASS}"
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vllm-e92d2c7a5b704b469bd73701aafa9004 | 20872968 | {
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"content": "{\"REASONING\": ['The context describes an experiment where HCC cell lines (HepG2, Hep3B, MHCC97L) and a normal liver cell line (L02) were infected with SG600-IL24 and Ad.IL-24.', 'The results showed that SG600-IL24 highly expressed the MDA-7/IL-24 gene in infected cells.', 'SG600-IL24 suppressed the growth of HCC cell lines with inhibition rates ranging from 72% to 85%, promoted apoptosis with rates ranging from 43.39% to 78.36%, and blocked the cell cycle in the G2/M phase.', 'These effects were observed in HCC cell lines but not in the normal liver cell line L02, indicating selective targeting of HCC cells.', 'The context also mentions that these effects were p53-independent, meaning they did not rely on the p53 status of the cells.', 'The answer accurately reflects these findings by stating that SG600-IL24 can selectively suppress the proliferation and apoptosis of HCC cell lines in vitro but not normal liver cell lines, and that it can enhance antitumor activity in HCC cell lines compared to Ad.IL-24.'], \"SCORE\": PASS}"
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vllm-ca5bc508a76d471e954b00166e77765f | 25405654 | {
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"content": "{\"REASONING\": ['The context describes a pilot study conducted in three Chinese medical schools to determine the benefits of introducing internet-based teaching methods.', 'The study involved both Chinese and foreign medical students, with a total of 1539 students participating.', 'The results showed that both Chinese and foreign students were highly proficient in internet usage and had positive attitudes towards computerized teaching methods.', 'A significant majority (88.37%) of students owned a computer and frequently used the internet, indicating their comfort with technology.', 'The two classes that used virtual classrooms performed significantly better on examinations compared to classes without internet forums.', 'These points collectively support the conclusion that computerized teaching methods, including virtual classrooms, can be beneficial for both Chinese and foreign medical students.'], \"SCORE\": PASS}"
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vllm-628ec65b44b4476f9d55a7669b42af7d | 20224364 | {
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"content": "{\"REASONING\": ['The CONTEXT describes a multi-institutional randomized controlled trial that investigated the effectiveness of maximal sterile barrier precautions (MSBPs) in preventing catheter-related bloodstream infections (CRBSIs) in general surgical units.', 'The study compared MSBPs to standard sterile barrier precautions (SSBPs) and found no significant difference in the rates of CRBSIs between the two groups.', 'The ANSWER correctly states that the study could not demonstrate better prevention of CRBSIs by MSBP compared with SSBP.', 'The ANSWER also mentions that a larger randomized controlled trial or a meta-analysis is necessary to reach a conclusion on this issue, which aligns with the CONTEXT indicating that the current study was not sufficient to draw a definitive conclusion.'], \"SCORE\": PASS}"
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vllm-d22ff500f3294ee6b18197c3f6e7d97e | 17335599 | {
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"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The CONTEXT provides specific data on the performance of the isolated gamma probe technique for sentinel node penile carcinoma detection.', 'The CONTEXT mentions a sensibility rate of 25% and a false-negative rate of 42.8%, which are indicators of poor performance.', 'The ANSWER accurately reflects the low sensibility and high false-negative rate mentioned in the CONTEXT.', 'The ANSWER concludes that the isolated gamma probe technique is unreliable, which is supported by the poor performance metrics provided in the CONTEXT.'], \"SCORE\": PASS}"
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vllm-bd3f33b1cb5e43059c90c2fd97ad7629 | 9665051 | {
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"model": "llama-3-70b",
"choices": [
{
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"message": {
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"content": "{\"REASONING\": ['The context describes an experiment where microbubbles with anti-ICAM-1 antibodies were tested for their ability to bind to activated coronary artery endothelial cells (ECs).', 'The results showed a significant increase in adhesion of these microbubbles to activated ECs compared to normal ECs, indicating specific binding.', 'The answer accurately reflects the findings from the context, stating that the microbubbles with anti-ICAM-1 antibody on their shell specifically bind to activated ECs overexpressing ICAM-1.', \"The answer also mentions the potential for diagnostic ultrasound with targeted contrast agents to characterize cell phenotype in vivo, which is consistent with the context's discussion of the potential for in vivo detection of LAMs.\"], \"SCORE\": PASS}"
},
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